title: Bleomycin sclerotherapy for lymphatic malformation after unsuccessful surgical excision: case report.
abstract: Lymphatic malformations (LMs) are benign cystic masses resulting from the abnormal development of lymphatic channels. Lymphatic malformations occur primarily in the head and neck region. Surgical excision of lymphatic malformation is followed by high rate of recurrence and a high risk of complications. Bleomycin is an established antineoplastic drug. It can be used as a sclerosing agent in vascular anomalies. We present a child who was unsuccessfully treated with four surgical resections, with peripheral palsy of facial nerve as complication. The lymphatic malformation was successfully treated in our institution with intralesional administration of bleomycin.
authors.affiliation: Department of Plastic and Reconstructive Surgery and Burns.
authors.forename: A
authors.initials: A
authors.lastname: Vlahovic
authors.affiliation: Department of Radiology, Institute for Mother and Child Health Care of Republic Serbia, New Belgrade, Serbia;
authors.forename: A
authors.initials: A
authors.lastname: Gazikalovic
authors.affiliation: Center for Diagnostic Imaging, Oncology Institute of Sremska Kamenica.
authors.forename: O
authors.initials: O
authors.lastname: Adjic
mesh_terms: D001761:Bleomycin / Q000627:therapeutic use*; D002648:Child; D006801:Humans; D044148:Lymphatic Abnormalities / Q000188:drug therapy* / Q000601:surgery; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D015911:Sclerotherapy; D016896:Treatment Outcome
chemical_list: D012597:Sclerosing Solutions; D001761:Bleomycin
keywords: Bleomycin; Lymphatic malformation; Sclerotherapy
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