title: Resolution of diarrhea in an immunocompromised patient with chronic norovirus gastroenteritis correlates with constitution of specific antibody blockade titer.
abstract: Norovirus gastroenteritis in immunocompromised hosts can result in a serious and prolonged diarrheal illness. We present a case of chronic norovirus disease during rituximab-bendamustine chemotherapy for non-Hodgkin's lymphoma. We show for the first time a correlation between norovirus strain-specific antibody blockade titers and symptom improvement in an immunocompromised host.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Westchester Medical Center, Valhalla, NY, USA. Bettina.Knoll@wmchealth.org.
authors.forename: Bettina M
authors.initials: BM
authors.lastname: Knoll
authors.affiliation: Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
authors.forename: Lisa C
authors.initials: LC
authors.lastname: Lindesmith
authors.affiliation: Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
authors.forename: Boyd L
authors.initials: BL
authors.lastname: Yount
authors.affiliation: Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.
authors.forename: Ralph S
authors.initials: RS
authors.lastname: Baric
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Francisco M
authors.initials: FM
authors.lastname: Marty
mesh_terms: D000914:Antibodies, Viral / Q000097:blood; D017250:Caliciviridae Infections; D003967:Diarrhea; D005260:Female; D005759:Gastroenteritis; D006801:Humans; D016867:Immunocompromised Host; D008875:Middle Aged; D029322:Norovirus
chemical_list: D000914:Antibodies, Viral
keywords: Immunocompromised host; Norovirus; Strain-specific antibody blockade titers
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