title: Patients Presenting with Advanced Human Immunodeficiency Virus Disease: Epidemiological Features by Age Group.
abstract: We explored factors influencing presentation with advanced human immunodeficiency virus (HIV) disease by age group. Data were derived from a city-wide cross-sectional survey of 759 HIV-infected adults living in Seoul, Korea. The significance of each observed factor was assessed via multivariate logistic regression. Of subjects aged 20-34 years, lower educational level had a positive influence on presentation with advanced HIV disease (adjusted odds ratio [aOR], 2.43; 95% confidence interval [CI], 1.36-4.34); those recently diagnosed with HIV were more likely to be presented with advanced HIV disease (aOR, 3.17; 95% CI, 0.99-10.2). Of the subjects aged 35-49 years, those w ith advanced HIV disease were more likely to have been diagnosed during health check-ups (aOR, 2.91; 95% CI, 1.15-7.32) or via clinical manifestations (aOR, 3.61; 95% CI, 1.39-9.36). Of the subjects aged ≥ 50 years, presentation with advanced HIV disease was significantly more common in older subjects (aOR per increment of 5 years, 2.06; 95% CI, 1.32-3.23) and less common among individuals diagnosed with HIV in 2000-2006 (aOR, 0.18; 95% CI, 0.04-0.83). In conclusion, a lower educational level in younger subjects and more advanced age in older subjects positively influence the presentation of advanced HIV disease.
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Cho Ryok
authors.identifier: 0000-0002-9212-8292
authors.initials: CR
authors.lastname: Kang
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Division of Infectious Diseases, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea.
authors.forename: Ji Hwan
authors.identifier: 0000-0002-7628-1182
authors.initials: JH
authors.lastname: Bang
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Department of Epidemiology, Seoul National University Graduate School of Public Health, Seoul, Korea.
authors.forename: Sung-Il
authors.identifier: 0000-0003-4085-1494
authors.initials: SI
authors.lastname: Cho
authors.affiliation: Division of Life & Health, Seoul Metropolitan Government, Seoul, Korea.
authors.forename: Kui Nam
authors.identifier: 0000-0001-5110-2179
authors.initials: KN
authors.lastname: Kim
authors.affiliation: Division of Life & Health, Seoul Metropolitan Government, Seoul, Korea.
authors.forename: Hee-Jin
authors.identifier: 0000-0002-8748-8146
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Bo Yeong
authors.identifier: 0000-0001-9336-8098
authors.initials: BY
authors.lastname: Ryu
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Soo Kyung
authors.identifier: 0000-0003-3767-1994
authors.initials: SK
authors.lastname: Cho
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Department of Epidemiology, Seoul National University Graduate School of Public Health, Seoul, Korea.
authors.forename: Young Hwa
authors.identifier: 0000-0003-2073-993X
authors.initials: YH
authors.lastname: Lee
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Myoung-Don
authors.identifier: 0000-0002-2344-7695
authors.initials: MD
authors.lastname: Oh
authors.affiliation: Seoul Center for Infectious Disease Control, Seoul, Korea.; Department of Family Medicine, Seoul National University College of Medicine, Seoul, Korea.
authors.forename: Jong-Koo
authors.identifier: 0000-0003-4833-1178
authors.initials: JK
authors.lastname: Lee
mesh_terms: D000328:Adult; D000367:Age Factors; D018791:CD4 Lymphocyte Count; D003430:Cross-Sectional Studies; D003710:Demography; D005260:Female; D015658:HIV Infections / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D056910:Republic of Korea / Q000453:epidemiology; D055815:Young Adult
keywords: Acquired Immune Deficiency Syndrome; Early Detection; HIV; Late Presentation; Low Education; Old Age; Seoul Metropolitan City
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