title: Use of minimal invasive extracorporeal circulation in cardiac surgery: principles, definitions and potential benefits. A position paper from the Minimal invasive Extra-Corporeal Technologies international Society (MiECTiS).
abstract: Minimal invasive extracorporeal circulation (MiECC) systems have initiated important efforts within science and technology to further improve the biocompatibility of cardiopulmonary bypass components to minimize the adverse effects and improve end-organ protection. The Minimal invasive Extra-Corporeal Technologies international Society was founded to create an international forum for the exchange of ideas on clinical application and research of minimal invasive extracorporeal circulation technology. The present work is a consensus document developed to standardize the terminology and the definition of minimal invasive extracorporeal circulation technology as well as to provide recommendations for the clinical practice. The goal of this manuscript is to promote the use of MiECC systems into clinical practice as a multidisciplinary strategy involving cardiac surgeons, anaesthesiologists and perfusionists.
authors.affiliation: Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
authors.forename: Kyriakos
authors.initials: K
authors.lastname: Anastasiadis
authors.affiliation: Department of Anesthesiology and Perioperative Medicine, University of Western Ontario, London, Canada.
authors.forename: John
authors.initials: J
authors.lastname: Murkin
authors.affiliation: Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
authors.forename: Polychronis
authors.initials: P
authors.lastname: Antonitsis
authors.affiliation: Department of Cardiothoracic Surgery, MediClin Heart Centre Coswig, Coswig, Germany.
authors.forename: Adrian
authors.initials: A
authors.lastname: Bauer
authors.affiliation: Department of Anaesthesia and Intensive Care, Policlinico S. Donato, Milan, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Ranucci
authors.affiliation: Department of Cardiovascular Surgery, University of Bern, Bern, Switzerland.
authors.forename: Erich
authors.initials: E
authors.lastname: Gygax
authors.affiliation: Department of Cardiothoracic Surgery, MediClin Heart Centre Coswig, Coswig, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Schaarschmidt
authors.affiliation: University Pierre and Marie Curie (Paris 06), Paris, France.
authors.forename: Yves
authors.initials: Y
authors.lastname: Fromes
authors.affiliation: Department of Cardiac Surgery, Regensburg, Germany.
authors.forename: Alois
authors.initials: A
authors.lastname: Philipp
authors.affiliation: Department of Anesthesiology and Pain Therapy, University of Bern, Bern, Switzerland.
authors.forename: Balthasar
authors.initials: B
authors.lastname: Eberle
authors.affiliation: Department of Cardiothoracic Surgery, Hammersmith Hospital, London, UK.
authors.forename: Prakash
authors.initials: P
authors.lastname: Punjabi
authors.affiliation: Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
authors.forename: Helena
authors.initials: H
authors.lastname: Argiriadou
authors.affiliation: Department of Cardiovascular Surgery, University of Bern, Bern, Switzerland.
authors.forename: Alexander
authors.initials: A
authors.lastname: Kadner
authors.affiliation: Department of Cardiovascular Surgery, University of Bern, Bern, Switzerland.
authors.forename: Hansjoerg
authors.initials: H
authors.lastname: Jenni
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, Ulm University, Ulm, Germany.
authors.forename: Guenter
authors.initials: G
authors.lastname: Albrecht
authors.affiliation: Department of Cardiothoracic Surgery, Amsterdam Medical Center, Amsterdam, Netherlands.
authors.forename: Wim
authors.initials: W
authors.lastname: van Boven
authors.affiliation: Department of Cardiothoracic and Vascular Surgery, Ulm University, Ulm, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Liebold
authors.affiliation: Heart Centre, University Hospital Ghent, Gent, Belgium.
authors.forename: Fillip
authors.initials: F
authors.lastname: de Somer
authors.affiliation: Department of Cardiothoracic Surgery, MediClin Heart Centre Coswig, Coswig, Germany.
authors.forename: Harald
authors.initials: H
authors.lastname: Hausmann
authors.affiliation: Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Deliopoulos
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Braunschweig, Germany.
authors.forename: Aschraf
authors.initials: A
authors.lastname: El-Essawi
authors.affiliation: Department of Adult Cardiac Surgery, Mater Dei Hospital, Bari, Italy.
authors.forename: Valerio
authors.initials: V
authors.lastname: Mazzei
authors.affiliation: Department of Cardiac Surgery, Oulu University Hospital, Oulu, Finland.
authors.forename: Fausto
authors.initials: F
authors.lastname: Biancari
authors.affiliation: Department of Surgery, Sidra Medical & Research Centre, Doha, Qatar.
authors.forename: Adam
authors.initials: A
authors.lastname: Fernandez
authors.affiliation: Department of Cardiothoracic Surgery, Maastricht University Medical Centre, Maastricht, Netherlands.
authors.forename: Patrick
authors.initials: P
authors.lastname: Weerwind
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Hospital of the Rhine University Bochum, Bad Oeynhausen, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Puehler
authors.affiliation: University Health Network, Toronto, Canada.
authors.forename: Cyril
authors.initials: C
authors.lastname: Serrick
authors.affiliation: St Antonius Hospital, Nieuwegein, Netherlands.
authors.forename: Frans
authors.initials: F
authors.lastname: Waanders
authors.affiliation: Department of Cardiovascular Surgery, Medline Hospitals, Adana, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Gunaydin
authors.affiliation: Department of Cardiothoracic Surgery, Wessex Cardiac Centre, University Hospital Southampton, Hampshire, UK.
authors.forename: Sunil
authors.initials: S
authors.lastname: Ohri
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, University Hospital of the Rhine University Bochum, Bad Oeynhausen, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Gummert
authors.affiliation: Department of Cardiothoracic Surgery, Hammersmith Hospital, London, UK Department of Cardiac Surgery, Bristol Heart Institute, Bristol, UK.
authors.forename: Gianni
authors.initials: G
authors.lastname: Angelini
authors.affiliation: Department of Cardiothoracic Surgery, German Heart Centre, Berlin, Germany.
authors.forename: Volkmar
authors.initials: V
authors.lastname: Falk
authors.affiliation: Department of Cardiovascular Surgery, University of Bern, Bern, Switzerland thierry.carrel@insel.ch.
authors.forename: Thierry
authors.initials: T
authors.lastname: Carrel
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods*; D032921:Consensus; D005112:Extracorporeal Circulation / Q000706:statistics & numerical data*; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000706:statistics & numerical data*; D012955:Societies, Medical
keywords: Cardiopulmonary bypass; Complications; Extracorporeal circulation; Minimally invasive extracorporeal circulation; Modular systems; Systemic inflammation reaction syndrome
references.citation: ASAIO J. 2009 Nov-Dec;55(6):602-7
references.pmid: 19783907
references.citation: Ann Thorac Surg. 2007 Nov;84(5):1515-20; discussion 1521
references.pmid: 17954055
references.citation: ASAIO J. 2009 Jan-Feb;55(1):58-62
references.pmid: 19092669
references.citation: J Artif Organs. 2007;10(2):92-5
references.pmid: 17574511
references.citation: Perfusion. 2010 Jul;25(4):197-203
references.pmid: 20515982
references.citation: ASAIO J. 2013 May-Jun;59(3):269-74
references.pmid: 23644614
references.citation: Ann Thorac Surg. 2011 Mar;91(3):944-82
references.pmid: 21353044
references.citation: J Extra Corpor Technol. 2010 Mar;42(1):30-9
references.pmid: 20437789
references.citation: Ann Thorac Surg. 1995 Aug;60(2):365-71
references.pmid: 7646097
references.citation: Artif Organs. 2004 Dec;28(12):1082-8
references.pmid: 15554936
references.citation: Anesth Analg. 2014 Jan;118(1):21-68
references.pmid: 24356157
references.citation: BMJ. 2012 Sep 11;345:e5798
references.pmid: 22968722
references.citation: Ann Thorac Surg. 2009 Jul;88(1):40-5; discussion 45-6
references.pmid: 19559186
references.citation: Eur J Cardiothorac Surg. 2014 Jul;46(1):152
references.pmid: 24047711
references.citation: Mol Cell Biochem. 2014 Oct;395(1-2):167-75
references.pmid: 24934242
references.citation: J Thorac Cardiovasc Surg. 2006 Feb;131(2):268-76
references.pmid: 16434253
references.citation: J Cardiothorac Surg. 2014 Aug 28;9:143
references.pmid: 25185963
references.citation: J Cardiothorac Surg. 2013 Apr 02;8:59
references.pmid: 23547910
references.citation: Ann Thorac Surg. 2009 Aug;88(2):529-35
references.pmid: 19632407
references.citation: Artif Organs. 2010 Jan;34(1):3-12
references.pmid: 19839992
references.citation: Interact Cardiovasc Thorac Surg. 2012 Nov;15(5):834-9
references.pmid: 22914806
references.citation: Eur J Cardiothorac Surg. 2013 Jun;43(6):1081-3
references.pmid: 23543201
references.citation: Int J Cardiol. 2013 Apr 5;164(2):158-69
references.pmid: 22325958
references.citation: Ann Thorac Surg. 2009 Jan;87(1):36-44; discussion 44-5
references.pmid: 19101265
references.citation: J Thorac Cardiovasc Surg. 2010 May;139(5):1162-9
references.pmid: 19775708
references.citation: Anesth Analg. 2007 Jan;104(1):51-8
references.pmid: 17179242
references.citation: Int J Cardiol. 2013 Oct 15;168(6):5336-43
references.pmid: 23992927
references.citation: J Cardiothorac Vasc Anesth. 2013 Oct;27(5):859-64
references.pmid: 23791499
references.citation: J Cardiothorac Vasc Anesth. 2013 Oct;27(5):865-75
references.pmid: 23706643
references.citation: ASAIO J. 2007 Jan-Feb;53(1):32-5
references.pmid: 17237646
references.citation: Ann Thorac Surg. 2005 Dec;80(6):2213-20
references.pmid: 16305874
references.citation: Eur J Cardiothorac Surg. 2002 Oct;22(4):527-33
references.pmid: 12297167
references.citation: Eur J Cardiothorac Surg. 2009 Nov;36(5):844-8
references.pmid: 19695898
references.citation: Crit Care. 2011 Aug 10;15(4):R192
references.pmid: 21831302
references.citation: Perfusion. 2015 Apr;30(3):195-200
references.pmid: 25564510
references.citation: Am Heart J. 2006 Jan;151(1):198
references.pmid: 16368318
references.citation: Ann Thorac Surg. 2005 Jul;80(1):238-43
references.pmid: 15975373
references.citation: Anesthesiology. 2011 Jan;114(1):12-3
references.pmid: 21178667
references.citation: Perfusion. 2010 May;25(3):133-7; discussion 138-9
references.pmid: 20442203
references.citation: Perfusion. 2011 Nov;26(6):470-8
references.pmid: 21859789
references.citation: Ann Thorac Surg. 2005 Dec;80(6):2326-32
references.pmid: 16305899
references.citation: Ann Thorac Surg. 2001 Nov;72(5):S1838-44
references.pmid: 11722118
references.citation: Ann Thorac Surg. 2015 Jan;99(1):115-22
references.pmid: 25440276
references.citation: Ann Thorac Surg. 2009 Mar;87(3):766-72
references.pmid: 19231386
references.citation: Perfusion. 2007 Jul;22(4):245-50
references.pmid: 18181512
references.citation: J Thorac Cardiovasc Surg. 2009 Jan;137(1):65-9
references.pmid: 19154905
references.citation: Eur J Cardiothorac Surg. 2014 Jan;45(1):69-74
references.pmid: 23666376
references.citation: Thorac Cardiovasc Surg. 2010 Jun;58(4):204-9
references.pmid: 20514574
references.citation: J Cardiothorac Vasc Anesth. 2013 Oct;27(5):972-82
references.pmid: 23623887
references.citation: Perfusion. 2015 Jul;30(5):389-94
references.pmid: 25143413
references.citation: Interact Cardiovasc Thorac Surg. 2009 Nov;9(5):832-6
references.pmid: 19671581
references.citation: Perfusion. 2013 Sep;28(5):412-8
references.pmid: 23625867
references.citation: Perfusion. 2010 Mar;25(2):65-70
references.pmid: 20179173
references.citation: J Cardiothorac Vasc Anesth. 2013 Aug;27(4 Suppl):S20-34
references.pmid: 23910533
references.citation: Ann Thorac Surg. 1995 Jun;59(6):1549-55
references.pmid: 7771838
references.citation: Anesth Analg. 2015 Apr;120(4):749-69
references.pmid: 25790208
references.citation: J Thorac Cardiovasc Surg. 1995 Jul;110(1):46-54
references.pmid: 7609568
references.citation: Eur J Echocardiogr. 2010 Aug;11(7):557-76
references.pmid: 20688767
references.citation: Heart Surg Forum. 2010 Apr;13(2):E116-23
references.pmid: 20444674
references.citation: Heart. 2009 Jun;95(12):964-9
references.pmid: 19342377
references.citation: J Thorac Cardiovasc Surg. 1983 Dec;86(6):845-57
references.pmid: 6606084
references.citation: Interact Cardiovasc Thorac Surg. 2009 Nov;9(5):797-801
references.pmid: 19661117
references.citation: Ann Thorac Surg. 2007 May;83(5):1760-6
references.pmid: 17462395
references.citation: Interact Cardiovasc Thorac Surg. 2015 Jan;20(1):68-73
references.pmid: 25323401
references.citation: Perfusion. 2013 Jan;28(1):47-53
references.pmid: 22907954
references.citation: Eur J Cardiothorac Surg. 2008 Nov;34(5):969-75
references.pmid: 18824368
references.citation: Interact Cardiovasc Thorac Surg. 2014 Oct;19(4):541-2
references.pmid: 25536672
references.citation: Perfusion. 2009 May;24(3):153-62
references.pmid: 19755462
references.citation: Heart. 2011 Jul;97(13):1082-8
references.pmid: 21357641
references.citation: Anaesthesia. 2011 Jun;66(6):488-92
references.pmid: 21501130
references.citation: Eur J Anaesthesiol. 2013 Nov;30(11):685-94
references.pmid: 24036568
references.citation: J Thorac Cardiovasc Surg. 2012 Sep;144(3):677-83
references.pmid: 22698563
references.citation: Interact Cardiovasc Thorac Surg. 2010 Dec;11(6):754-7
references.pmid: 20847068
references.citation: Ann Thorac Surg. 1993 Feb;55(2):552-9
references.pmid: 8431082