title: An update on polysaccharide-based nanomaterials for antimicrobial applications.
abstract: Scientific community has made a lot of efforts to combat the infectious diseases using antimicrobial agents, but these are associated with problems of development of multi-drug resistance and their adverse side effects. To tackle these challenges, nanocarrier-based drug delivery system using polysaccharides has received enormous attention in the past few years. These antimicrobial agents can become more efficacious when adsorbed, entrapped, or linked to polysaccharides. In addition, these nanocarrier-based systems provide an increase in the surface area of the drug and are able to achieve the targeted drug delivery as well as used for the synthesis of packaging materials with improved mechanical strength, barrier, and antimicrobial properties. This review focuses on potential therapeutic applications of nanocarrier-based drug delivery systems using polysaccharides for antimicrobial applications.
authors.affiliation: Quality Control & Quality Assurance Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, , 180001, India.|CSIR-Academy of Scientific & Innovative Research, Govt. of India, New Delhi, India.
authors.forename: Divya
authors.initials: D
authors.lastname: Arora
authors.affiliation: Quality Control & Quality Assurance Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, , 180001, India.|CSIR-Academy of Scientific & Innovative Research, Govt. of India, New Delhi, India.
authors.forename: Nisha
authors.initials: N
authors.lastname: Sharma
authors.affiliation: Quality Control & Quality Assurance Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, , 180001, India.|CSIR-Academy of Scientific & Innovative Research, Govt. of India, New Delhi, India.
authors.forename: Vishal
authors.initials: V
authors.lastname: Sharma
authors.affiliation: Quality Control & Quality Assurance Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, , 180001, India.
authors.forename: Vidushi
authors.initials: V
authors.lastname: Abrol
authors.affiliation: Bioorganic Chemistry Division, CSIR-Indian Institute of Integrative Medicine, Jammu, , 180001, India.
authors.forename: Ravi
authors.initials: R
authors.lastname: Shankar
authors.affiliation: Quality Control & Quality Assurance Division, CSIR-Indian Institute of Integrative Medicine, Canal Road, Jammu, , 180001, India. sundeepjaglan@iiim.ac.in.|CSIR-Academy of Scientific & Innovative Research, Govt. of India, New Delhi, India. sundeepjaglan@iiim.ac.in.
authors.forename: Sundeep
authors.initials: S
authors.lastname: Jaglan
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D004337:Drug Carriers; D016503:Drug Delivery Systems; D049329:Nanostructures; D011134:Polysaccharides / Q000378:metabolism*
chemical_list: D000890:Anti-Infective Agents; D004337:Drug Carriers; D011134:Polysaccharides
keywords: Antimicrobial; Chitosan; Dextran; Hyaluronic acid; Nanoparticle; Polysaccharide