title: Failure to decolonize mupirocin and linezolid resistant MRSA from a patient with necrotizing soft tissue infection.
abstract: Colonization with methicillin resistant Staphylococcus aureus (MRSA) is considered to be a major risk factor for skin and soft tissue infections. We present a case of a patient suffering from necrotizing soft tissue infection and exposed to multiple antibiotics and developed colonization with linezolid resistant MRSA (LRMRSA). He could not be decolonized despite prolonged conventional or modified MRSA decolonization protocols.
authors.affiliation: Department of Clinical Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India. Electronic address: sumit_rai@yahoo.com.
authors.forename: Sumit
authors.initials: S
authors.lastname: Rai
authors.affiliation: Department of Clinical Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Mayuri
authors.initials: M
authors.lastname: Rani
authors.affiliation: Department of Clinical Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Debapriya D
authors.initials: DD
authors.lastname: Choudhury
authors.affiliation: Department of Clinical Microbiology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Narendra P
authors.initials: NP
authors.lastname: Singh
authors.affiliation: Department of Surgery, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Department of Clinical Microbiology and Infectious Diseases, Chacha Nehru Bal Chikitsalaya, Geeta Colony, Delhi, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Manchanda
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D006801:Humans; D007194:India; D000069349:Linezolid / Q000627:therapeutic use*; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D008875:Middle Aged; D016712:Mupirocin / Q000627:therapeutic use*; D018461:Soft Tissue Infections / Q000188:drug therapy / Q000382:microbiology*; D013207:Staphylococcal Skin Infections / Q000188:drug therapy / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents; D016712:Mupirocin; D000069349:Linezolid
keywords: Decontamination; G2576U mutation; Linezolid resistant MRSA