title: Impact of Auditory Context on Executed Motor Actions.
abstract: The auditory and motor systems are strongly coupled, as is evident in the specifically tight motor synchronization that occurs in response to regularly occurring auditory cues compared with cues of other modalities. Timing of rhythmic action is known to rely on multiple neural centers including the cerebellum and the basal-ganglia which have access to both motor cortical and spinal circuitries. To date, however, there is little information on the motor mechanisms that operate during preparation and execution of rhythmic vs. non-rhythmic movements. We measured acceleration profile and muscle activity while subjects performed tapping movements in response to auditory cues. We found that when tapping at random intervals there was a higher variability of both acceleration profile and muscle activity during motor preparation compared to rhythmic tapping. However, the specific rhythmic context (cued, self-paced, or syncopation) did not affect the motor parameters of the executed taps. Finally, during entrainment we found a gradual as opposed to episodic change in low-level motor parameters (i.e., preparatory muscle activity) that was strongly correlated with changes in high-level parameters (i.e., shift in the reaction time to negative asynchrony). These findings suggest that motor entrainment involves not only adjusting the timing of movement but also modifying parameters that are related to its production. These changes in motor output were insensitive to the specifics of the rhythmic cue: although it took subjects different times to become entrained to different types of rhythmic cues, the motor actions produced once entrainment was obtained were indistinguishable. These findings suggest that motor entrainment involves not only adjusting the timing of movement but also modifying parameters related to its production. The reduced variability of muscle activity during the preparatory period could be one mechanism used by the motor system to enhance the accuracy of motor timing.
authors.affiliation: Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, Edmond and Lily Safra Center for Brain Research, The Hebrew University Jerusalem, Israel.
authors.forename: Michal
authors.initials: M
authors.lastname: Yoles-Frenkel
authors.affiliation: Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, Edmond and Lily Safra Center for Brain Research, The Hebrew University Jerusalem, Israel.
authors.forename: Maayan
authors.initials: M
authors.lastname: Avron
authors.affiliation: Department of Medical Neurobiology, Institute of Medical Research Israel-Canada, Edmond and Lily Safra Center for Brain Research, The Hebrew University Jerusalem, Israel.
authors.forename: Yifat
authors.initials: Y
authors.lastname: Prut
keywords: EMG; auditory–motor interactions; muscle activity; rhythmic movements; tapping
references.citation: Nat Neurosci. 2013 Dec;16(12):1888-95
references.pmid: 24141310
references.citation: Nat Rev Neurosci. 2005 Oct;6(10):755-65
references.pmid: 16163383
references.citation: Neurosci Lett. 2002 Nov 8;332(3):205-9
references.pmid: 12399015
references.citation: J Neurosci. 1982 Sep;2(9):1329-45
references.pmid: 7119878
references.citation: J Neurophysiol. 2009 Dec;102(6):3191-202
references.pmid: 19812296
references.citation: Annu Rev Neurosci. 2013 Jul 8;36:313-36
references.pmid: 23725000
references.citation: Phys Ther. 1982 Feb;62(2):161-8
references.pmid: 7058221
references.citation: Int Rev Neurobiol. 1997;41:555-73
references.pmid: 9378608
references.citation: Brain Cogn. 2002 Feb;48(1):66-79
references.pmid: 11812033
references.citation: Network. 2003 Nov;14(4):747-63
references.pmid: 14653501
references.citation: Curr Opin Neurobiol. 2010 Dec;20(6):696-703
references.pmid: 20926287
references.citation: Ann N Y Acad Sci. 2003 Nov;999:364-73
references.pmid: 14681157
references.citation: Proc Biol Sci. 1999 Apr 22;266(1421):853-7
references.pmid: 10343408
references.citation: Exp Brain Res. 2004 May;156(1):111-7
references.pmid: 15007587
references.citation: Exp Brain Res. 2001 Feb;136(3):331-9
references.pmid: 11243475
references.citation: J Physiol Paris. 2015 Feb-Jun;109(1-3):104-17
references.pmid: 25636373
references.citation: Percept Psychophys. 1995 Apr;57(3):305-17
references.pmid: 7770322
references.citation: Curr Opin Neurobiol. 2004 Apr;14(2):225-32
references.pmid: 15082329
references.citation: J Neurophysiol. 2011 Apr;105(4):1722-31
references.pmid: 21273324
references.citation: Acta Neurobiol Exp (Wars). 2004;64(3):415-26
references.pmid: 15283483
references.citation: Acta Psychol (Amst). 1967;27:204-12
references.pmid: 6062212
references.citation: J Neurophysiol. 2007 Jul;98(1):145-52
references.pmid: 17460103
references.citation: Psychon Bull Rev. 2005 Dec;12(6):969-92
references.pmid: 16615317
references.citation: Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19156-61
references.pmid: 19850874
references.citation: Exp Brain Res. 2004 Nov;159(1):129-34
references.pmid: 15365663
references.citation: Brain Res Brain Res Rev. 1995 Nov;21(3):301-14
references.pmid: 8806018
references.citation: Hum Brain Mapp. 2002 Dec;17 (4):214-29
references.pmid: 12395389
references.citation: Nature. 1999 Oct 7;401(6753):590-4
references.pmid: 10524626
references.citation: Parkinsonism Relat Disord. 2004 Mar;10(3):143-8
references.pmid: 15036168
references.citation: Science. 1977 Oct 21;198(4314):317-9
references.pmid: 410103
references.citation: Science. 1996 Dec 6;274(5293):1724-6
references.pmid: 8939866
references.citation: Ann N Y Acad Sci. 2002 Dec;978:302-17
references.pmid: 12582062
references.citation: Exp Brain Res. 1996 Jun;110(1):117-30
references.pmid: 8817263
references.citation: IEEE Eng Med Biol Mag. 1999 Mar-Apr;18(2):101-8
references.pmid: 10101675