title: Tubulocystic oncocytoma of the kidney: a case study and review of literature with focus on implications for differential diagnosis.
abstract: Renal oncocytoma (RO) can rarely present with a multilocular or tubulocystic growth pattern that may cause significant diagnostic difficulties with a variety of cystic renal cell carcinomas (RCC). Distinguishing these RO variants from their many RCC mimickers is critical because of its typical benign clinical course. Herein, we report a case of RO with extensive tubulocystic architectures on a 42-year-old female patient and discuss the clinicopathologic characterizations of this unusual RO variant with an emphasis on the wide spectrum of differential diagnoses of a variety of primary or secondary renal tumors that are featuring of both oncocytic cell changes and tubulocystic growth patterns.
authors.affiliation: Department of Urology, Zhejiang Provincial People's HospitalHangzhou 310014, Zhejiang, PR China; Department of Pathology, Zhejiang Provincial People's HospitalHangzhou 310014, Zhejiang, PR China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: Department of Pathology, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, PR China.
authors.forename: Jie
authors.initials: J
authors.lastname: Ma
authors.affiliation: Department of Radiology, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, PR China.
authors.forename: Cui-Yun
authors.initials: CY
authors.lastname: Wu
authors.affiliation: Department of Urology, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, PR China.
authors.forename: Da-Hong
authors.initials: DH
authors.lastname: Zhang
authors.affiliation: Department of Pathology, Zhejiang Provincial People's Hospital Hangzhou 310014, Zhejiang, PR China.
authors.forename: Ming
authors.initials: M
authors.lastname: Zhao
mesh_terms: D018249:Adenoma, Oxyphilic / Q000473:pathology*; D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D033162:Incidental Findings; D007680:Kidney Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Renal tumor; differential diagnosis; oncocytoma; tubulocystic carcinoma
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