title: Associations of Inter- and Intraday Temperature Change With Mortality.
abstract: In this study we evaluated the association between temperature variation and mortality and compared it with the contribution due to mean daily temperature in 6 cities with different climates. Quasi-Poisson time series regression models were applied to estimate the associations (relative risk and 95% confidence interval) of mean daily temperature (99th and 1st percentiles, with temperature of minimum mortality as the reference category), interday temperature variation (difference between the mean temperatures of 2 neighboring days) and intraday temperature variation (diurnal temperature range (DTR)) (referred to as median variation) with mortality in 6 cities: London, United Kingdom; Madrid, Spain; Stockholm, Sweden; New York, New York; Miami, Florida; and Houston, Texas (date range, 1985-2010). All cities showed a substantial increase in mortality risk associated with mean daily temperature, with relative risks reaching 1.428 (95% confidence interval (CI): 1.329, 1.533) for heat in Madrid and 1.467 (95% CI: 1.385, 1.555) for cold in London. Inconsistent results for inter-/intraday change were obtained, except for some evidence of protective associations on hot and cold days (relative risk (RR) = 0.977 (95% CI: 0.955, 0.999) and RR = 0.981 (95% CI: 0.971, 0.991), respectively) in Madrid and on cold days in Stockholm (RR = 0.989, 95% CI: 0.980, 0.998). Our results indicate that the association between mortality and temperature variation is generally minimal compared with mean daily temperatures, although further research on intraday changes is needed.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Vicedo-Cabrera
authors.forename: Bertil
authors.initials: B
authors.lastname: Forsberg
authors.forename: Aurelio
authors.initials: A
authors.lastname: Tobias
authors.forename: Antonella
authors.initials: A
authors.lastname: Zanobetti
authors.forename: Joel
authors.initials: J
authors.lastname: Schwartz
authors.forename: Ben
authors.initials: B
authors.lastname: Armstrong
authors.forename: Antonio
authors.initials: A
authors.lastname: Gasparrini
mesh_terms: D002947:Cities / Q000706:statistics & numerical data*; D005060:Europe; D006801:Humans; D009026:Mortality; D012044:Regression Analysis; D013696:Temperature; D014481:United States
keywords: ambient temperature; diurnal temperature range; mortality; temperature variation
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