title: Clinical Diagnosis and Management of Breast Cancer.
abstract: The diagnosis and management of breast cancer are undergoing a paradigm shift from a one-size-fits-all approach to an era of personalized medicine. Sophisticated diagnostics, including molecular imaging and genomic expression profiles, enable improved tumor characterization. These diagnostics, combined with newer surgical techniques and radiation therapies, result in a collaborative multidisciplinary approach to minimizing recurrence and reducing treatment-associated morbidity. This article reviews the diagnosis and treatment of breast cancer, including screening, staging, and multidisciplinary management.
authors.affiliation: Breast Imaging Division, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania elizabeth.mcdonald@uphs.upenn.edu.
authors.forename: Elizabeth S
authors.initials: ES
authors.lastname: McDonald
authors.affiliation: Division of Hematology/Oncology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Clark
authors.affiliation: Department of Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Julia
authors.initials: J
authors.lastname: Tchou
authors.affiliation: Department of Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; and.
authors.forename: Paul
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Department of Radiation Oncology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Gary M
authors.initials: GM
authors.lastname: Freedman
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000628:therapy*; D019468:Disease Management; D005260:Female; D006801:Humans; D058990:Molecular Targeted Therapy / Q000639:trends*; D009364:Neoplasm Recurrence, Local; D057285:Precision Medicine
chemical_list: D000970:Antineoplastic Agents
keywords: breast cancer diagnosis; breast cancer imaging; breast cancer management; pathology; precision medicine; radiation; targeted therapy