title: Angioedema-Urticaria Due to Acitretin.
abstract: Acitretin is a synthetic oral retinoid that has been used for a number of dermatological diseases. Several side effects of acitretin have been reported such as teratogenicity, cheilitis, xerosis, dyslipidemia, and photosensitivity. Many drugs, mainly antibiotics and nonsteroidal anti-inflammatory drugs, can cause angioedema-urticaria. We present the case of angioedema-urticaria due to acitretin, confirmed by oral provocation test, in a 61-year-old man with psoriasis. To the best of our knowledge, only 1 case of angioedema due to oral acitretin has been reported in the literature so far. We report this case to draw attention that acitretin may cause angioedema-urticaria and to inform patients about this risk besides other side effects due to acitretin.
authors.affiliation: Department of Dermatology, Faculty of Medicine, Sakarya University, Sakarya, Turkey.
authors.forename: Berna
authors.initials: B
authors.lastname: Solak
authors.forename: Nurcan
authors.initials: N
authors.lastname: Metin
authors.forename: Mustafa Teoman
authors.initials: MT
authors.lastname: Erdem
mesh_terms: D017255:Acitretin / Q000009:adverse effects* / Q000627:therapeutic use; D000799:Angioedema / Q000139:chemically induced*; D006801:Humans; D007641:Keratolytic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy; D014581:Urticaria / Q000139:chemically induced*
chemical_list: D007641:Keratolytic Agents; D017255:Acitretin