title: [Intracellular and extracellular functions of phosphorus compound in the body].
abstract: Phosphorus, as a phosphate is a component of bone, cellular membrane, and also high-energy phosphate compounds, and nucleic acids. Also phosphate acts as a buffer to maintain the pH and is concerned with functional regulation of several proteins and intracellular signaling through the phosphorylation/dephosphorylation. Thus phosphorus plays a variety of important roles intracellular and extracellular component. A disorder of phosphate homeostasis results bone disorder and general metabolic dysfunction of all body tissues and organs.
authors.affiliation: Department of Molecular Nutrition, Institute of Biomedical Sciences，Tokushima University Graduate School, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Segawa
authors.affiliation: Department of Molecular Nutrition, Institute of Biomedical Sciences，Tokushima University Graduate School, Japan.
authors.forename: Ai
authors.initials: A
authors.lastname: Hanazaki
authors.affiliation: Department of Molecular Nutrition, Institute of Biomedical Sciences，Tokushima University Graduate School, Japan.
authors.forename: Ken-ichi
authors.initials: K
authors.lastname: Miyamoto
mesh_terms: D000818:Animals; D001847:Bone Diseases / Q000209:etiology; D001842:Bone and Bones / Q000378:metabolism; D002021:Buffers; D002462:Cell Membrane / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008659:Metabolic Diseases / Q000209:etiology; D009696:Nucleic Acids / Q000378:metabolism; D010710:Phosphates / Q000378:metabolism / Q000502:physiology*; D010766:Phosphorylation; D011506:Proteins / Q000502:physiology; D012463:Saliva; D015398:Signal Transduction / Q000502:physiology
chemical_list: D002021:Buffers; D009696:Nucleic Acids; D010710:Phosphates; D011506:Proteins