title: [Asbestos and respiratory diseases].
abstract: Previous occupational asbestos exposure (more rarely environmental or domestic exposure) may induce various pleural and/or pulmonary, benign or malignant diseases, sometimes with a very long latency for malignant mesothelioma (MM). Asbestos has been widely extracted and used in Western countries and in emerging or developing countries, resulting in a peak of MM incidence in France around 2020 and likely in a world pandemic of asbestos-induced diseases. These patients have mostly benign respiratory diseases (pleural plugs) but may also be diagnosed with lung cancer or malignant pleural mesothelioma, and have a global poor outcome. New therapeutic tools (targeted therapies, immunotherapy…) with first promising results are developed. However, it is crucial to obtain a full ban of asbestos use worldwide, and to do a regular follow-up of asbestos-exposed subjects, mostly if they are already diagnosed with benign respiratory diseases. Finally, new cancers (larynx and ovary) were recently added to the list of asbestos-induced tumors.
authors.affiliation: CHU de Lille, institut Pasteur de Lille, université de Lille, pneumologie et oncologie thoracique, CIIL, Inserm U1019, 59000 Lille, France. Electronic address: arnaud.scherpereel@chru-lille.fr.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Scherpereel
mesh_terms: D001194:Asbestos / Q000009:adverse effects*; D001195:Asbestosis / Q000209:etiology; D005355:Fibrosis / Q000209:etiology; D006801:Humans; D008175:Lung Neoplasms / Q000139:chemically induced; D008654:Mesothelioma / Q000139:chemically induced; D000086002:Mesothelioma, Malignant; D010994:Pleura / Q000473:pathology; D012120:Respiration Disorders / Q000139:chemically induced*
chemical_list: D001194:Asbestos