title: Clostridium septicum Infection Associated with Necrotizing Pancreatitis, Transmural Gastric Necrosis, and Liquefaction of the Spleen.
abstract: Spontaneous infection with Clostridium septicum (C. septicum) is rare, but when isolated it is commonly associated with malignancy. We report a case of a 47-year-old man with infected pancreatic necrosis involving greater than 80% of the pancreas, transmural gastric necrosis, and liquefaction necrosis of the spleen. Initial cultures revealed C. septicum infection. He was managed with prompt aggressive surgical debridément, resection, appropriate broad spectrum antibiotics, and early enteral nutrition.
authors.affiliation: Department of General Surgery, Oregon Health and Science University, 3181 SW San Jackson Park Road, Portland, OR, 97239, USA. zhoum@ohsu.edu.
authors.forename: Minhao
authors.initials: M
authors.lastname: Zhou
authors.affiliation: Department of General Surgery, Oregon Health and Science University, Portland, OR, USA.
authors.forename: Robert G
authors.initials: RG
authors.lastname: Martindale
keywords: Clostridium septicum; Gastric necrosis; Malignancy; Necrotizing pancreatitis; Spleen necrosis