title: [Treatment of castration-resistant prostate cancer: Evidence-based clinical practice].
abstract: OBJECTIVE
  To introduce the framework of evidence-based practice with a case of castration-resistant prostate cancer (CRPC) as an example.
  
  
  METHODS
  A clinical question was formulated according the clinical scenario. A systematic search was conducted for the published literature in the databases of PubMed, EMBASE, Cochrane Library, Clinical Trial Registries, and Web of Knowledge up to Dec 2014. The identified literature was reviewed for quality appraisal before the evidence was applied to clinical practice.
  
  
  RESULTS
  The treatment was effective and the patient achieved disease remission.
  
  
  CONCLUSIONS
  Evidence-based practice should be integrated with clinical scenario, current evidence, and patients' willingness, and follow a systematic framework.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Rui-xian
authors.initials: RX
authors.lastname: Peng
authors.forename: Guo-wei
authors.initials: GW
authors.lastname: Shi
authors.forename: Shi-yao
authors.initials: SY
authors.lastname: Chen
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ding
authors.forename: Jia-yang
authors.initials: JY
authors.lastname: He
mesh_terms: D019317:Evidence-Based Medicine; D006801:Humans; D008297:Male; D009919:Orchiectomy; D064129:Prostatic Neoplasms, Castration-Resistant / Q000628:therapy*