title: Practical Synthesis of Pachastrissamine (Jaspine B), 2-epi-Pachastrissamine, and the 2-epi-Pyrrolidine Analogue.
abstract: The practical syntheses of pachastrissamine (jaspine B), 2-epi-pachastrissamine, and the 2-epimer of the pyrrolidine analogue were accomplished via the stereoselective reduction of an allylketone derived from commercially available diethyl D-tartrate and the cross-metathesis of an allyltetrahydrofuran or allypyrrolidine with 1-tridecene as key steps.
authors.affiliation: Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Fujiwara
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.forename: Wenqi
authors.initials: W
authors.lastname: Niu
authors.forename: Kazuki
authors.initials: K
authors.lastname: Hashimoto
authors.forename: Hisanori
authors.initials: H
authors.lastname: Nambu
authors.forename: Takayuki
authors.initials: T
authors.lastname: Yakura
mesh_terms: D008968:Molecular Conformation; D011759:Pyrrolidines / Q000138:chemical synthesis* / Q000737:chemistry; D013110:Sphingosine / Q000031:analogs & derivatives* / Q000138:chemical synthesis / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D011759:Pyrrolidines; C468594:pachastrissamine; D013110:Sphingosine