title: Drug eluting biliary stents to decrease stent failure rates: A review of the literature.
abstract: Biliary stenting is clinically effective in relieving both malignant and non-malignant obstructions. However, there are high failure rates associated with tumor ingrowth and epithelial overgrowth as well as internally from biofilm development and subsequent clogging. Within the last decade, the use of prophylactic drug eluting stents as a means to reduce stent failure has been investigated. In this review we provide an overview of the current research on drug eluting biliary stents. While there is limited human trial data regarding the clinical benefit of drug eluting biliary stents in preventing stent obstruction, recent research suggests promise regarding their safety and potential efficacy.
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Joseph
authors.initials: J
authors.lastname: Shatzel
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Jisoo
authors.initials: J
authors.lastname: Kim
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Kartik
authors.initials: K
authors.lastname: Sampath
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Sharjeel
authors.initials: S
authors.lastname: Syed
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Saad
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Zilla H
authors.initials: ZH
authors.lastname: Hussain
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Kabir
authors.initials: K
authors.lastname: Mody
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: J Marc
authors.initials: JM
authors.lastname: Pipas
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Stuart
authors.initials: S
authors.lastname: Gordon
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Timothy
authors.initials: T
authors.lastname: Gardner
authors.affiliation: Joseph Shatzel, J Marc Pipas, Section of Hematology-Oncology, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, United States.
authors.forename: Richard I
authors.initials: RI
authors.lastname: Rothstein
keywords: Bile ducts; Cholangiocarcinoma; Endoscopy; Pancreas
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