title: The intersection of nonalcoholic fatty liver disease and obesity.
abstract: Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide and recently emerged as the most rapidly increasing indication for liver transplant. Although obesity is a risk factor for NAFLD, overlap between these two entities is incompletely understood. We highlight recent insights into the pathogenesis of human NAFLD in relation to obesity and discuss advances in the diagnosis and treatment of NAFLD.
authors.affiliation: Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Woo Baidal
authors.affiliation: Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University Medical Center, New York, NY 10032, USA. jl3553@cumc.columbia.edu.
authors.forename: Joel E
authors.initials: JE
authors.lastname: Lavine
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism; D017667:Adipocytes / Q000166:cytology; D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D015992:Body Mass Index; D004032:Diet; D018450:Disease Progression; D005355:Fibrosis / Q000378:metabolism; D022781:Hepatocytes / Q000166:cytology; D006801:Humans; D007249:Inflammation; D007333:Insulin Resistance; D008099:Liver / Q000378:metabolism; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications* / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D009765:Obesity / Q000150:complications* / Q000378:metabolism; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000378:metabolism; D012307:Risk Factors; D015431:Weight Loss
chemical_list: D015415:Biomarkers; D017382:Reactive Oxygen Species; D000255:Adenosine Triphosphate