title: Sorafenib-induced Scrotal Eczema.
abstract: Sorafenib is an orally active, small-molecule multikinase inhibitor that blocks tumor cell proliferation and angiogenesis. Studies have shown that it is a highly potent, selective inhibitor of vascular endothelial growth factor receptors 2 and 3, platelet-derived growth factor-β, RAF, FLT-3, and c-Kit. This drug was recently approved for the treatment of metastatic renal cell carcinoma and hepatocellular carcinoma. We report a case of a patient treated with sorafenib for metastatic renal cell carcinoma who developed scrotal eczema.
authors.affiliation: Department of Urology, Hitit University Çorum Training and Research Hospital, Çorum, Turkey.
authors.forename: Selahattin
authors.initials: S
authors.lastname: Çalışkan
keywords: Hand-foot skin reaction; Scrotal eczema; Sorafenib
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