title: Thyroid Cancer Epidemiology in Iran: a Time Trend Study.
abstract: BACKGROUND
  Considering the rising incidence of thyroid cancer worldwide, the aim of our study was to investigate the temporal trends in the incidence of this cancer in a large population of Iranian patients.
  
  
  METHODS
  We used the Iran Cancer Data System (ICDS) Registry to assess the thyroid cancer trend from 2004 to 2010 with regard to different genders, age groups, and morphologies. To do this we analyzed the data of 10,913 new cases of thyroid cancer that occurred during these years.
  
  
  RESULTS
  The incidence rate (per one year) of thyroid cancer was 2.20 per 100,000 persons between 2004 and 2010 in Iran. Papillary thyroid cancer was the most common histology type, with an annual rate of 0.29 in Iran. The highest rate of prevalence in thyroid cancer was observed at the age of 45 years at the time of diagnosis. We found a female-to-male ratio of 2 in Iran. A significant decrease was detected in the trend of thyroid cancer in children <19y, which was not correlated to the trend of older patients.
  
  
  CONCLUSIONS
  As expected, the trend of thyroid cancer increased over the 7 years, primarily contributed by papillary thyroid cancer. A rising pattern of incidence was seen in all the age groups except patients aged under 19 years.
authors.affiliation: Department of Otolaryngology, Head and Neck Surgery, Shahid Beheshti University of Medical Sciences, Tehran, Iran E-mail : dr.rozitajafari57@yahoo.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Safavi
authors.forename: Fereidoun
authors.initials: F
authors.lastname: Azizi
authors.forename: Rozita
authors.initials: R
authors.lastname: Jafari
authors.forename: Samira
authors.initials: S
authors.lastname: Chaibakhsh
authors.forename: Amir Ali
authors.initials: AA
authors.lastname: Safavi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000453:epidemiology* / Q000473:pathology; D002291:Carcinoma, Papillary; D002648:Child; D005260:Female; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012042:Registries; D000077273:Thyroid Cancer, Papillary; D013961:Thyroid Gland / Q000473:pathology; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000473:pathology; D055815:Young Adult