title: A new dimeric anthraquinone from endophytic Talaromyces sp. YE3016.
abstract: A new unsymmetrical dimeric anthraquinone, 3-demethyl-3-(2-hydroxypropyl)-skyrin (1) was isolated from the solid-state fermentation extract of an endophytic fungal strain Talaromyces sp. YE 3016, together with five known compounds, skyrin (2), oxyskyrin (3), emodin (4), 1,3,6-trihydroxy-8-methyl-anthraquinone (5) and ergosterol (6). The structure of the new compound was elucidated on the basis of spectroscopic analysis. Compounds 1-3 exhibited moderate cytotoxic activities against MCF-7 cell line.
authors.affiliation: a Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan Institute of Microbiology , Yunnan University , Kunming , P.R. China.
authors.forename: Xiao-Song
authors.initials: XS
authors.lastname: Xie
authors.affiliation: a Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan Institute of Microbiology , Yunnan University , Kunming , P.R. China.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Fang
authors.affiliation: b School of Chemical Science and Technology , Yunnan University , Kunming , P.R. China.
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
authors.affiliation: a Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan Institute of Microbiology , Yunnan University , Kunming , P.R. China.
authors.forename: Shou-Peng
authors.initials: SP
authors.lastname: Zhang
authors.affiliation: a Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan Institute of Microbiology , Yunnan University , Kunming , P.R. China.
authors.forename: Hong-Xia
authors.initials: HX
authors.lastname: Wei
authors.affiliation: a Key Laboratory for Microbial Resources of the Ministry of Education, Yunnan Institute of Microbiology , Yunnan University , Kunming , P.R. China.
authors.forename: Shao-Hua
authors.initials: SH
authors.lastname: Wu
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000737:chemistry / Q000302:isolation & purification; D005285:Fermentation; D006801:Humans; D061986:MCF-7 Cells; D032901:Talaromyces / Q000378:metabolism*
chemical_list: D000880:Anthraquinones; D000970:Antineoplastic Agents; C009274:skyrin
keywords: Talaromyces sp; dimeric anthraquinone; endophytic fungi; skyrin