title: Epidemiological survey of mucus extravasation phenomenon at an oral pathology referral center during a 43 year period.
abstract: BACKGROUND
  Mucoceles are common benign pseudocystic lesions of the oral cavity; their main etiological factors are trauma and ductal obstruction. Two histological patterns are found: mucus retention phenomenon (MRP) and mucus extravasation phenomenon (MEP). Mucus extravasation phenomenon is the more common histological subtype and it mainly affects the lower lip. The knowledge of its main clinical features and management is important to assist health professionals in clinical practice.
  
  
  OBJECTIVE
  This study aimed to determine the relative frequency and distribution of oral mucoceles in an oral pathology reference center.
  
  
  METHODS
  Cross-sectional historical study that analyzed all cases pathologically diagnosed as mucus extravasation phenomenon by the department of anatomic pathology of an oral pathology referral center from June of 1970 to May of 2014, considering the clinical characteristics of the lesion and those relating to the patient. SPSS v. 20.0 software for Windows was used for descriptive analysis.
  
  
  RESULTS
  During 43 years, 719 cases of mucus extravasation phenomenon (54.7% men and 45.3% women) were registered, with the lower lip as the most commonly affected site (n=484; 67.3%). The average age of patients was 20.8 years (SD±14.4) with a peak occurrence in the second decade of life. Most professionals had oral mucocele/ranula (n=606; 84.3%) as the initial clinical impression.
  
  
  CONCLUSIONS
  Mucus extravasation phenomenon is a lesion that primarily affects young patients, affecting mainly the lower lip, and is commonly found in oral diagnostic services.
authors.affiliation: Universidade Federal do Ceará (UFC), Fortaleza, CE, Brazil.
authors.forename: Thâmara Manoela Marinho
authors.initials: TM
authors.lastname: Bezerra
authors.affiliation: Universidade Federal de Campina Grande (UFCG), Campina Grande, PB, Brasil.
authors.forename: Bárbara Vanessa de Brito
authors.initials: BV
authors.lastname: Monteiro
authors.affiliation: Universidade Federal da Bahia (UFBA), Salvador, BA, Brazil.
authors.forename: Águida Cristina Gomes
authors.initials: ÁC
authors.lastname: Henriques
authors.affiliation: Universidade de Pernambuco (UPE), Arcoverde, PE, Brazil.
authors.forename: Marianne
authors.initials: M
authors.lastname: de Vasconcelos Carvalho
authors.affiliation: Universidade Estadual da Paraíba (UEPB), Campina Grande, PB, Brazil.
authors.forename: Cassiano Francisco Weege
authors.initials: CF
authors.lastname: Nonaka
authors.affiliation: Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN, Brazil. Electronic address: mccmiguel@hotmail.com.
authors.forename: Márcia Cristina
authors.initials: MC
authors.lastname: da Costa Miguel
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D009078:Mucocele / Q000453:epidemiology*; D009093:Mucus / Q000378:metabolism; D011159:Population Surveillance; D012189:Retrospective Studies; D012466:Salivary Gland Diseases / Q000453:epidemiology*; D013997:Time Factors; D055815:Young Adult
keywords: Glândulas salivares menores; Minor salivary glands; Mucocele; Ranula
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