title: Bilateral Reduction Mammaplasty as an Oncoplastic Technique for the Management of Early-Stage Breast Cancer in Women with Macromastia.
abstract: OBJECTIVE
  Lumpectomy may result in contour deformities or breast asymmetry in women with breast cancer and macromastia. This study investigates the use of bilateral reduction mammaplasty, with the tumor and margins included within the reduction specimen.
  
  
  METHODS
  Twenty-four patients who underwent lumpectomy with immediate bilateral reduction mammaplasty for unilateral breast cancer were included. Patient medical records were reviewed for demographic, oncological, and surgical characteristics.
  
  
  RESULTS
  Mean patient age was 57 years, and mean body mass index was 32.2 kg/m(2). Mean tumor size was 1.7 cm. All tumor margins were free of neoplastic involvement. No difference was noted between the ipsilateral and contralateral resection weights (P = .81). Adjuvant radiation therapy was delivered to 21 patients (88%). There were no significant differences in postoperative total (P = .36), major (P = .44), or minor (P = .71) complications between the tumor and nontumor sides. Only 1 patient required additional revision surgery following the initial lumpectomy with bilateral reduction mammaplasty.
  
  
  CONCLUSIONS
  Lumpectomy with bilateral reduction mammaplasty did not compromise surgical margins. Lumpectomy with bilateral reduction mammaplasty may allow for adequate surgical treatment of breast cancer while avoiding significant breast asymmetry in women with macromastia.
authors.affiliation: Section of Plastic Surgery and Reconstructive Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor.
authors.forename: Russell E
authors.initials: RE
authors.lastname: Ettinger
authors.affiliation: Section of Plastic Surgery and Reconstructive Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor.
authors.forename: Shailesh
authors.initials: S
authors.lastname: Agarwal
authors.affiliation: Center for Plastic & Reconstructive Surgery, St Joseph Mercy Hospital, Ypsilanti, Mich.
authors.forename: Paul H
authors.initials: PH
authors.lastname: Izenberg
authors.affiliation: Center for Plastic & Reconstructive Surgery, St Joseph Mercy Hospital, Ypsilanti, Mich.
authors.forename: Richard J
authors.initials: RJ
authors.lastname: Beil
authors.affiliation: Center for Plastic & Reconstructive Surgery, St Joseph Mercy Hospital, Ypsilanti, Mich.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Sherick
keywords: breast cancer; breast reconstruction; lumpectomy; oncoplastic; reduction mammaplasty
references.citation: Aesthetic Plast Surg. 2007 Jan-Feb;31(1):94-100
references.pmid: 17205249
references.citation: Ann Surg. 2008 Aug;248(2):154-62
references.pmid: 18650623
references.citation: Am J Surg. 2004 May;187(5):647-50; discussion 650-1
references.pmid: 15135684
references.citation: Ann Plast Surg. 2012 Sep;69(3):250-5
references.pmid: 21862918
references.citation: Plast Reconstr Surg. 2006 Jan;117(1):1-11; discussion 12-4
references.pmid: 16404237
references.citation: Plast Reconstr Surg. 2008 Dec;122(6):1631-47
references.pmid: 19050516
references.citation: N Engl J Med. 2002 Oct 17;347(16):1233-41
references.pmid: 12393820
references.citation: Surg Oncol. 2010 Dec;19(4):e95-e102
references.pmid: 19716288
references.citation: Ann Plast Surg. 2007 Sep;59(3):235-42
references.pmid: 17721207
references.citation: Plast Reconstr Surg. 2009 Jul;124(1):9-17
references.pmid: 19568039
references.citation: Plast Reconstr Surg. 2003 Mar;111(3):1102-9
references.pmid: 12621180
references.citation: Ann Surg Oncol. 2010 Oct;17 Suppl 3:242-4
references.pmid: 20853040
references.citation: Radiother Oncol. 1994 Nov;33(2):106-12
references.pmid: 7708953
references.citation: CA Cancer J Clin. 2002 Sep-Oct;52(5):277-300
references.pmid: 12363326
references.citation: Am J Surg. 2001 Mar;181(3):215-20
references.pmid: 11376574
references.citation: Ann Plast Surg. 2015 Oct;75(4):370-5
references.pmid: 24691307
references.citation: Plast Reconstr Surg. 2015 Jun;135(6):963e-971e
references.pmid: 26017612
references.citation: Int J Radiat Oncol Biol Phys. 1983 Dec;9(12):1807-13
references.pmid: 6662749