title: Evidence for improved outcome following use of hemostatic fibrin sealants in HPB surgery?
abstract: BACKGROUND
  The development of fibrin sealants has been progressing; they are now often applied as fibrinogen-coated collagen patches.
  
  
  METHODS
  The concept has been increasingly applied in hepato-pancreato-biliary surgery, for example, following liver resection, and to some extent also in pancreatic surgery, both in order to reinforce the pancreatic anastomosis at pancreaticoduodenectomy and to seal the pancreatic stump following distal pancreatectomy.
  
  
  CONCLUSIONS
  High quality evidence in the form of major prospective, randomized clinical studies is still lacking on in the field of HPB. There is also an the absence of proper cost-utility analyses.
authors.affiliation: Department of Surgery, Clinical Sciences Lund, Lund University, Lund University Hospital, 221 85, Lund, Sweden. roland.andersson@med.lu.se.
authors.forename: R
authors.initials: R
authors.lastname: Andersson
keywords: Fibrin sealants; Hepatobiliary surgery
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