title: [Medicine at the "edge of chaos". Life, entropy and complexity].
abstract: The aim of this paper is to help physicians and health professionals, who constantly seek to improve their knowledge for the benefit of the ill, to incorporate new conceptual and methodological tools to understand the complexity inherent to the field of medicine. This article contains notions that are unfamiliar to these professionals and are intended to foster reflection and learning. It poses the need to define life from a thermodynamic point of view, linking it closely to complex systems, nonlinear dynamics and chaotic behavior, as well as to redefine conventional physiological control mechanisms based on the concept of homeostasis, and to travel the path that starts with the search for extraterrestrial life up to exposing medicine "near the edge of chaos". Complexity transcends the biological aspects; it includes a subjective and symbolic/social dimension. Viewing disease as a heterogeneous and multi-causal phenomenon can give rise to new approaches for the sick.
authors.affiliation: Instituto de Investigaciones Médicas Alfredo Lanari, Universidad de Buenos Aires, Argentina. E-mail: eldevito@gmail.com.
authors.forename: Eduardo L
authors.initials: EL
authors.lastname: De Vito
mesh_terms: D019277:Entropy; D005118:Extraterrestrial Environment; D006706:Homeostasis; D006801:Humans; D019369:Life; D008511:Medicine; D017711:Nonlinear Dynamics
keywords: chaos theory; complexity; entropy; homeostasis; life