title: Primary Squamous Cell Carcinoma of Trachea Arising 4 Years After Radioiodine Treatment of Papillary Carcinoma of Thyroid.
abstract: Primary squamous cell carcinoma (SCC) of the trachea is rare. Here, we presented a rare case of primary SCC of the trachea arising 4 years after radioiodine (RAI) treatment of papillary carcinoma of the thyroid. In this case, concomitant uptake of I-RAI and F-FDG was demonstrated in the thyroidal mass with tracheal invasion, which mimicked mixed well-differentiated and dedifferentiated thyroid carcinoma. The diagnosis of SCC of the trachea was made only after tracheal biopsy. This case illustrates that FDG-avid thyroid bed lesion, in the presence of thyroid carcinoma, may not necessarily be related to the thyroid pathology.
authors.affiliation: From the Department of Nuclear Medicine, National Cancer Institute, Putrajaya, Malaysia.
authors.forename: Teik Hin
authors.initials: TH
authors.lastname: Tan
authors.forename: Boon Nang
authors.initials: BN
authors.lastname: Lee
mesh_terms: D002277:Carcinoma / Q000532:radiotherapy*; D002291:Carcinoma, Papillary; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging*; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals / Q000627:therapeutic use; D000077273:Thyroid Cancer, Papillary; D013964:Thyroid Neoplasms / Q000532:radiotherapy*; D014134:Tracheal Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D007457:Iodine Radioisotopes; D019275:Radiopharmaceuticals