title: Synthetic musk in seafood products from south Europe using a quick, easy, cheap, effective, rugged and safe extraction method.
abstract: This study aims at developing a method for the determination of 9 synthetic musk compounds in seafood products by combining the quick, easy, cheap, effective, rugged, and safe (QuEChERS) method and determination by gas chromatography mass spectrometry (GC-EI-MS). Method detection limits (MDL) ranging between 0.001 and 1.94 ng g(-1) were obtained. The linearity is higher than 0.9899 in the range MDL - 100 ng g(-1) with precision below 18% and recoveries between 46% and 120% were obtained. The method was applied to quantify musk compounds in seafood products from the European southwest coast (oysters, mussels, salmon organs, glass eels). Galaxolide and Tonalide exhibited the highest concentration levels ranging between MDL - 96.4 ng g(-1) and MDL - 6.85 ng g(-1), respectively. Contamination levels observed for the two nitro musks (musk xylene and musk ketone) are significantly lower ranging between MDL - 0.6 ng g(-1) and MDL - 0.09 ng g(-1), respectively. Analysis of different organs of salmons showed higher concentrations in liver and gonad than in muscle tissues.
authors.affiliation: National Health Institute Doctor Ricardo Jorge, (INSA), Av. Padre Cruz, 1649-016 Lisbon, Portugal.
authors.forename: M
authors.initials: M
authors.lastname: Saraiva
authors.affiliation: Laboratoire de Chimie Analytique Bio-inorganique et Environnement (LCABIE), Institut Pluridisciplinaire de Recherche sur l'Environnement et les Matériaux (IPREM), CNRS UMR 5254, Université de Pau et des Pays de l'Adour, Hélioparc Pau Pyrénées, 2, av. P. Angot, 64053 Pau Cedex 9, France.
authors.forename: J
authors.initials: J
authors.lastname: Cavalheiro
authors.affiliation: Laboratoire de Chimie Analytique Bio-inorganique et Environnement (LCABIE), Institut Pluridisciplinaire de Recherche sur l'Environnement et les Matériaux (IPREM), CNRS UMR 5254, Université de Pau et des Pays de l'Adour, Hélioparc Pau Pyrénées, 2, av. P. Angot, 64053 Pau Cedex 9, France.
authors.forename: L
authors.initials: L
authors.lastname: Lanceleur
authors.affiliation: Laboratoire de Chimie Analytique Bio-inorganique et Environnement (LCABIE), Institut Pluridisciplinaire de Recherche sur l'Environnement et les Matériaux (IPREM), CNRS UMR 5254, Université de Pau et des Pays de l'Adour, Hélioparc Pau Pyrénées, 2, av. P. Angot, 64053 Pau Cedex 9, France. Electronic address: mathilde.monperrus@univ-pau.fr.
authors.forename: M
authors.initials: M
authors.lastname: Monperrus
mesh_terms: D000818:Animals; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D057230:Limit of Detection; D017747:Seafood / Q000032:analysis*; D014992:Xylenes / Q000302:isolation & purification*
chemical_list: D014992:Xylenes; C031447:musk xylene; C031448:musk ketone
keywords: Biological samples; Coastal environment; Environmental monitoring; LVI-GC–MS; Polycyclic musks; QuEChERS