title: Deep eutectic solvents in countercurrent and centrifugal partition chromatography.
abstract: Deep eutectic solvents (DESs) were evaluated as solvents in centrifugal partition chromatography, a liquid-liquid chromatography separation technology. To this end, the partition coefficients of ten natural compounds of different hydrophobicity were determined in non-aqueous biphasic systems containing DES. The influence of the composition of DESs and the presence of water in the biphasic system on the partition coefficient were also examined. In addition, several process relevant physical properties of the biphasic system, such as the density and viscosity of the phases, were measured. A mixture of three to four hydrophobic compounds was successfully separated in a centrifugal partition extractor using a heptane/ethanol/DES biphasic system.
authors.affiliation: Biothermodynamics, TUM School of Life and Food Sciences Weihenstephan, Technische Universität München, 85354 Freising, Germany.
authors.forename: Simon
authors.initials: S
authors.lastname: Roehrer
authors.affiliation: Biothermodynamics, TUM School of Life and Food Sciences Weihenstephan, Technische Universität München, 85354 Freising, Germany.
authors.forename: Franziska
authors.initials: F
authors.lastname: Bezold
authors.affiliation: Chair of Separation Science and Technology, Friedrich Alexander University Erlangen-Nuremberg, 91058 Erlangen, Germany.
authors.forename: Eva Marra
authors.initials: EM
authors.lastname: García
authors.affiliation: Biothermodynamics, TUM School of Life and Food Sciences Weihenstephan, Technische Universität München, 85354 Freising, Germany; Chair of Separation Science and Technology, Friedrich Alexander University Erlangen-Nuremberg, 91058 Erlangen, Germany. Electronic address: mirjana.minceva@tum.de.
authors.forename: Mirjana
authors.initials: M
authors.lastname: Minceva
mesh_terms: D002853:Chromatography, Liquid / Q000379:methods*; D003377:Countercurrent Distribution / Q000379:methods*; D057927:Hydrophobic and Hydrophilic Interactions; D012997:Solvents / Q000737:chemistry*; D014783:Viscosity
chemical_list: D012997:Solvents
keywords: Centrifugal partition chromatography; Centrifugal partition extractor; Countercurrent chromatography; Deep eutectic solvents; Non-aqueous biphasic liquid systems