title: A patient with Factor V Leiden and a related pulmonary embolism.
abstract: Venous thromboembolism (VTE) is a complication associated with the hypercoaguable state produced in patients with Factor V Leiden deficiency. Clinically, patients can present with pleuritic chest pain, dyspnea, tachycardia, and unilateral leg swelling, warmth, erythema, and pain. Treatment with heparin is urgent, and patients should continue an anticoagulation drug regimen at home.
authors.affiliation: Janet Downs practices emergency medicine at Genesis Healthcare in Zanesville, Ohio. William A. Childers, Jr., is director of the PA program at West Liberty (W.Va.) University. The authors have disclosed no potential conflicts of interest, financial or otherwise.
authors.forename: Janet
authors.initials: J
authors.lastname: Downs
authors.forename: William A
authors.initials: WA
authors.lastname: Childers
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002637:Chest Pain / Q000235:genetics*; D005165:Factor V / Q000235:genetics*; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000235:genetics*
chemical_list: D000925:Anticoagulants; C095381:factor V Leiden; D005165:Factor V; D006493:Heparin