title: [Study on the molecular epidemiology of bacterial infection in patients in cardiac surgical intensive care unit].
abstract: OBJECTIVE
  To investigate the molecular epidemiology of acinetobacter baumannii and pseudomonas aeruginosa isolated from clinical specimens from patients on mechanical ventilation.
  
  
  METHODS
  From October to December, 2012, acinetobacter baumannii and pseudomonas aeruginosa strains were isolated from patients on mechanical ventilation. Antibiotic susceptibility data of all strains was collected. Homology of the strains was analyzed by the methods of pulsed field gel electrophoresis (PFGE) genotype, meanwhile, the clinical data was also analyzed.
  
  
  RESULTS
  Of the 15 pathogens isolated from patients on mechanical ventilation, 7 acinetobacter baumannii strains had different genotypes, indicating specific clustering in a specific location, so acinetobacter baumannii should be a scattered infection or colonized strains. Parts of 8 pseudomonas aeruginosa strains came from the same clone and confirm the existence of cross-infection of nosocomial infections.
  
  
  CONCLUSIONS
  The result shows that nosocomial infection outbreak doesn't occur, there is a small range of cross-infection of pseudomonas aeruginosa.
authors.affiliation: Institute of Clinical Pharmacology, Peking University First Hospital, Beijing 100034, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Gao
authors.affiliation: Email: lyzx5857@163.com.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Lü
authors.forename: Lanqing
authors.initials: L
authors.lastname: Cui
authors.forename: Liying
authors.initials: L
authors.lastname: Sun
mesh_terms: D040981:Acinetobacter baumannii; D001424:Bacterial Infections / Q000453:epidemiology*; D003422:Critical Care; D003428:Cross Infection; D016521:Electrophoresis, Gel, Pulsed-Field; D005838:Genotype; D006801:Humans; D007362:Intensive Care Units; D017720:Molecular Epidemiology; D011550:Pseudomonas aeruginosa