title: The cellulose synthase companion proteins act non-redundantly with CELLULOSE SYNTHASE INTERACTING1/POM2 and CELLULOSE SYNTHASE 6.
abstract: Cellulose is a cell wall constituent that is essential for plant growth and development, and an important raw material for a range of industrial applications. Cellulose is synthesized at the plasma membrane by massive cellulose synthase (CesA) complexes that track along cortical microtubules in elongating cells of Arabidopsis through the activity of the protein CELLULOSE SYNTHASE INTERACTING1 (CSI1). In a recent study we identified another family of proteins that also are associated with the CesA complex and microtubules, and that we named COMPANIONS OF CELLULOSE SYNTHASE (CC). The CC proteins protect the cellulose synthesising capacity of Arabidopsis seedlings during exposure to adverse environmental conditions by enhancing microtubule dynamics. In this paper we provide cell biology and genetic evidence that the CSI1 and the CC proteins fulfil distinct functions during cellulose synthesis. We also show that the CC proteins are necessary to aid cellulose synthesis when components of the CesA complex are impaired. These data indicate that the CC proteins have a broad role in aiding cellulose synthesis during environmental changes and when core complex components are non-functional.
authors.affiliation: a Max-Planck-Institute of Molecular Plant Physiology , Am Muehlenberg 1, Potsdam , Germany.|b Targenomix, Am Muehlenberg 11, Potsdam , Germany.
authors.forename: Anne
authors.initials: A
authors.lastname: Endler
authors.affiliation: c School of Biosciences, University of Melbourne , Parkville, Melbourne , Australia.
authors.forename: Rene
authors.initials: R
authors.lastname: Schneider
authors.affiliation: c School of Biosciences, University of Melbourne , Parkville, Melbourne , Australia.
authors.forename: Christopher
authors.initials: C
authors.lastname: Kesten
authors.affiliation: c School of Biosciences, University of Melbourne , Parkville, Melbourne , Australia.|d ARC Center of Excellence in Plant Cell Walls, School of Biosciences, University of Melbourne , Parkville , Victoria , Australia.
authors.forename: Edwin R
authors.initials: ER
authors.lastname: Lampugnani
authors.affiliation: c School of Biosciences, University of Melbourne , Parkville, Melbourne , Australia.|d ARC Center of Excellence in Plant Cell Walls, School of Biosciences, University of Melbourne , Parkville , Victoria , Australia.
authors.forename: Staffan
authors.initials: S
authors.lastname: Persson
mesh_terms: D017360:Arabidopsis / Q000378:metabolism*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism*; D005964:Glucosyltransferases / Q000378:metabolism*; D008870:Microtubules / Q000378:metabolism; D009154:Mutation / Q000235:genetics
chemical_list: D029681:Arabidopsis Proteins; C551801:CSI1 protein, Arabidopsis; D002352:Carrier Proteins; D005964:Glucosyltransferases; C457769:PRC1 protein, Arabidopsis; C478648:cellulose synthase
keywords: Abiotic stress; Arabidopsis; cellulose; microtubules; plant cell walls
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