title: Effect of Induced Pluripotent Stem Cell Technology in Blood Banking.
abstract: Population aging has imposed cost-effective alternatives to blood donations. Artificial blood is still at the preliminary stages of development, and the need for viable cells seems unsurmountable. Because large numbers of viable cells must be promptly available for clinical use, stem cell technologies, expansion, and banking represent ideal tools to ensure a regular supply. Provided key donors can be identified, induced pluripotent stem cell (iPSC) technology could pave the way to a new era in transfusion medicine, just as it is already doing in many other fields of medicine. The present review summarizes the current state of research on iPSC technology in the field of blood banking, highlighting hurdles, and promises.
authors.affiliation: North-Western Tuscany Blood Bank, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Focosi
authors.affiliation: Retrovirus Center and Virology Section, Department of Translational Research, University of Pisa, Pisa, Italy Virology Unit, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy mauro.pistello@med.unipi.it.
authors.forename: Mauro
authors.initials: M
authors.lastname: Pistello
mesh_terms: D001771:Blood Banks; D001802:Blood Substitutes; D004912:Erythrocytes; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D014019:Tissue Donors
chemical_list: D001802:Blood Substitutes
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