title: Comparison of thermal and mechanical quantitative sensory testing in client-owned dogs with chronic naturally occurring pain and normal dogs.
abstract: Detecting dogs with central sensitization (CS) secondary to chronic pain is hampered by the current inability to measure this condition. The current study aimed to use quantitative sensory testing (QST) to measure (CS) in normal dogs and dogs with painful degenerative joint disease (DJD). It was hypothesized that QST would differ between these two groups of animals. Mechanical and thermal sensory thresholds obtained in animals with DJD-associated pain on two time points 28 days apart were compared with those of normal dogs. Values of sensory thresholds in DJD dogs obtained 28 days after the first evaluation were significantly lower than the results on the first day of evaluation but no differences were found when these results were compared with those of normal dogs. In conclusion, whether QST is different between dogs with chronic pain and normal dogs needs further investigation using a larger group of animals and age, weight and sex matched groups.
authors.affiliation: Comparative Pain Research Laboratory (CPRL), Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, 27606, USA; Faculté de médecine vétérinaire, Université de Montréal, 3200 Rue Sicotte, Saint-Hyacinthe, QC J2S 2M2, Canada.
authors.forename: Mila
authors.initials: M
authors.lastname: Freire
authors.affiliation: Comparative Pain Research Laboratory (CPRL), Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, 27606, USA.
authors.forename: David
authors.initials: D
authors.lastname: Knazovicky
authors.affiliation: Comparative Pain Research Laboratory (CPRL), Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, 27606, USA.
authors.forename: Beth
authors.initials: B
authors.lastname: Case
authors.affiliation: Comparative Pain Research Laboratory (CPRL), Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, 27606, USA.
authors.forename: Andrea
authors.initials: A
authors.lastname: Thomson
authors.affiliation: Comparative Pain Research Laboratory (CPRL), Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, 27606, USA; Center for Comparative Medicine and Translational Research. Department of Clinical Sciences, College of Veterinary Medicine, NC State University, Raleigh, NC, 27606 USA; Center for Pain Research and Innovation, UNC School of Dentistry, Chapel Hill, NC USA. Electronic address: duncan_lascelles@ncsu.edu.
authors.forename: B Duncan X
authors.initials: BD
authors.lastname: Lascelles
mesh_terms: D000818:Animals; D059333:Central Nervous System Sensitization; D004283:Dog Diseases / Q000503:physiopathology*; D004285:Dogs; D010003:Osteoarthritis / Q000503:physiopathology / Q000662:veterinary*; D010146:Pain / Q000503:physiopathology / Q000662:veterinary*; D012684:Sensory Thresholds
keywords: Canine; Central Sensitization; Chronic pain; Mechanical sensory threshold; Thermal sensory threshold