title: Study of Effectiveness and Safety of Percutaneous Balloon Mitral Valvulotomy for Treatment of Pregnant Patients with Severe Mitral Stenosis.
abstract: BACKGROUND
  In pregnant women mitral stenosis is the commonest cardiac valvular lesion. When it is present in majorly severe condition it leads to maternal and fetal morbidity and mortality. In mitral stenosis pregnancy can lead to development of heart failure.
  
  
  OBJECTIVE
  To evaluate the safety and efficacy of balloon mitral valvulotomy (BMV) in pregnant females with severe mitral stenosis.
  
  
  METHODS
  A total of 30 pregnant patients who underwent BMV were included in the study from July 2011 to November 2013. Clinical follow-up during pregnancy was done every 3 months until delivery and after delivery. The mean follow up time after BMV was 6.72±0.56 months.
  
  
  RESULTS
  From the 30 pregnant females 14 (46.67%) and 16 (53.3%) patients underwent BMV during the third and second trimester of pregnancy respectively. The mean mitral valve area was 0.85+0.16 cm(2) before BMV that increased to 1.60+0.27 cm(2) (p<0.0001) immediately after BMV. Peak and mean diastolic gradients had decreased significantly within 48 hours after the procedure (p<0.001) but remained very much unchanged at 6.72 month period of follow-up. Two patients had an increase in mitral regurgitation by 2 grades.
  
  
  CONCLUSIONS
  During pregnancy BMV technique is safe and effective in patients with severe mitral stenosis. This results in marked symptomatic relief along with long term maternal and fetal outcomes.
authors.affiliation: Associate Professor, Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC) , Ahmedabad, India .
authors.forename: Hasit Sureshbhai
authors.initials: HS
authors.lastname: Joshi
authors.affiliation: Associate Professor, Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC) , Ahmedabad, India .
authors.forename: Jagjeet Kishanrao
authors.initials: JK
authors.lastname: Deshmukh
authors.affiliation: Head of Department, Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC) , Ahmedabad, India .
authors.forename: Jayesh Somabhai
authors.initials: JS
authors.lastname: Prajapati
authors.affiliation: Associate Professor, Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC) , Ahmedabad, India .
authors.forename: Sibasis Shahsikant
authors.initials: SS
authors.lastname: Sahoo
authors.affiliation: DM Resident, Department of Cardiology, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC) , Ahmedabad, India .
authors.forename: Pooja Maheshbhai
authors.initials: PM
authors.lastname: Vyas
authors.affiliation: Research Fellow, Department of Research, U. N. Mehta Institute of Cardiology and Research Centre (UNMICRC) , Ahmedabad, India .
authors.forename: Iva Vipul
authors.initials: IV
authors.lastname: Patel
keywords: Cardiac abnormalities; Cardiac valvular; Morbidity and mortality
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