title: Placental involvement by non-Hodgkin lymphoma in a Crohn disease patient on long-term thiopurine therapy.
abstract: We report the first published case of aggressive diffuse large B-cell (non-Hodgkin) lymphoma in a 35-year-old pregnant woman who had Crohn disease and was taking long-term thiopurine therapy: the patient developed placental insufficiency, and there was intrauterine fetal death.
authors.affiliation: Gastroenterology and Hepatology Unit.
authors.forename: G
authors.initials: G
authors.lastname: Chen
authors.affiliation: Department of Clinical Haematology.
authors.forename: P
authors.initials: P
authors.lastname: Crispin
authors.affiliation: Departmemt of Anatomical Pathology, ACT Pathology.
authors.forename: M
authors.initials: M
authors.lastname: Cherian
authors.affiliation: Departmemt of Anatomical Pathology, ACT Pathology.|Australian National University Medical School.
authors.forename: J E
authors.initials: JE
authors.lastname: Dahlstrom
authors.affiliation: Fetal Medicine Unit, Centenary Hospital for Women and Children, Canberra Hospital, Canberra, New South Wales, Australia.
authors.forename: F F
authors.initials: FF
authors.lastname: Sethna
authors.affiliation: Gastroenterology and Hepatology Unit.
authors.forename: G
authors.initials: G
authors.lastname: Kaye
authors.affiliation: Gastroenterology and Hepatology Unit.|Australian National University Medical School.
authors.forename: P
authors.initials: P
authors.lastname: Pavli
authors.affiliation: Gastroenterology and Hepatology Unit.|Australian National University Medical School.
authors.forename: K
authors.initials: K
authors.lastname: Subramaniam
mesh_terms: D000328:Adult; D001379:Azathioprine / Q000008:administration & dosage / Q000009:adverse effects*; D003424:Crohn Disease / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis*; D005260:Female; D005313:Fetal Death / Q000209:etiology; D006801:Humans; D008228:Lymphoma, Non-Hodgkin / Q000139:chemically induced / Q000150:complications / Q000175:diagnosis*; D010920:Placenta; D010927:Placental Insufficiency / Q000139:chemically induced / Q000175:diagnosis*; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000139:chemically induced / Q000175:diagnosis*
chemical_list: D001379:Azathioprine
keywords: Crohn disease; non-Hodgkin lymphoma; placental insufficiency; thiopurines