title: Can We Be Less Radical with Surgery for Early Cervical Cancer?
abstract: Although a rare cancer in the developed world due to the success of cervical screening programmes, cervical cancer remains one of the most common cancers diagnosed in women under the age of 35 years old. Radical hysterectomy and more recently radical trachelectomy have been highly effective in curing the majority of women with early stage disease. Many, however, are left with long-term 'survivorship' issues including bowel, bladder and sexual dysfunction. In view of these chronic co-morbidities, many clinicians now consider whether a less radical approach to surgery may be an option for some women. This review focuses on the current evidence for the safety of conservative surgery for early stage cervical cancer with regard to cure rates in comparison to standard management, as well as any improvement in short and long-term morbidity associated with a more conservative approach.
authors.affiliation: Department of Gynaecological Oncology, G18, Sheffield Teaching Hospital NHS Foundation Trust, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK. madeleine.macdonald@sth.nhs.uk.
authors.forename: Madeleine C
authors.initials: MC
authors.lastname: Macdonald
authors.affiliation: Department of Gynaecological Oncology, G18, Sheffield Teaching Hospital NHS Foundation Trust, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, UK. John.Tidy@sth.nhs.uk.
authors.forename: John A
authors.initials: JA
authors.lastname: Tidy
mesh_terms: D001294:Attitude to Health; D005260:Female; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D008197:Lymph Node Excision; D020360:Neoadjuvant Therapy; D002583:Uterine Cervical Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*
keywords: Cervical cancer; Hysterectomy; Lymphadenopathy; Morbidity; Outcome; Radical; Simple; Stage 1; Surgery
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