title: Optical coherence tomography angiography characteristics of polypoidal choroidal vasculopathy.
abstract: To analyse the morphological characteristics of polypoidal choroidal vasculopathy (PCV) on optical coherence tomography angiography (OCT-A).
  
  
  
  Prospective study with consecutive patients affected with PCV were included. All patients underwent a complete ophthalmological examination including fundus photography, fluorescein angiography, indocyanine green angiography, spectral-domain OCT and OCT-A.
  
  
  
  Twelve eyes of 12 patients (mean age 72.6±10.5 years; 4 men and 8 women) were included for analysis. In all eyes (12/12) the segmentation of the choriocapillaris layer on OCT-A revealed the branching vascular network (BVN) as a hyperflow lesion. OCT-A segmentation of the choriocapillaris layer in correspondence of the polypoidal lesion showed in 3/12 eyes (25%) a hyperflow round structure, surrounded by a hypointense halo, and in 9/12 eyes (75%) a hypoflow round structure.
  
  
  
  The OCT-A is a non-invasive imaging modality allowing the visualisation of different structures in PCV. The BVN is constantly clearly detected. The hypoflow round structure appearance of the polyp in OCT-A, is probably due to an unusual blood flow inside the polypoidal lesions, contrasting with the BVN. Further improvement in OCT-A knowledge will provide information on the specificity of the different intensity characteristics in PCV.
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Mayer
authors.initials: M
authors.lastname: Srour
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Querques
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Oudy
authors.initials: O
authors.lastname: Semoun
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Ala
authors.initials: A
authors.lastname: El Ameen
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Miere
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Sikorav
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Olivia
authors.initials: O
authors.lastname: Zambrowski
authors.affiliation: Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université de Paris Est Créteil, Créteil, France.
authors.forename: Eric H
authors.initials: EH
authors.lastname: Souied
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply / Q000000981:diagnostic imaging*; D020256:Choroidal Neovascularization / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008297:Male; D008875:Middle Aged; D011127:Polyps / Q000175:diagnosis* / Q000503:physiopathology; D011446:Prospective Studies; D012039:Regional Blood Flow; D012171:Retinal Vessels / Q000000981:diagnostic imaging* / Q000503:physiopathology; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence / Q000379:methods*
keywords: Imaging; Neovascularisation; Retina