title: [Takayasu arteritis].
abstract: Takayasu arteritis is a chronic inflammatory vasculitis of unknown origin affecting large vessels, predominantly the aorta and its main branches. Vessel inflammation leads to wall thickening, fibrosis, and stenosis. The lesions are often asymptomatic leading to limb numbness, transient ischemic attack, cardiovascular event and renovascular hypertension. Treatment is based on corticosteroids, immunosuppressant and biologics if necessary. Endovascular treatment and open-surgery can be useful for end-organ ischemia relief.
authors.affiliation: Pôle cardiovasculaire rénal et métabolique, service de médecine vasculaire, hôpital européen Georges-Pompidou, hôpitaux universitaires Paris Ouest, université Paris Descartes, AP-HP, 20, rue Leblanc, 75015 Paris, France; Centre national de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, 75015 Paris, France; Inserm U970 PARCC, université Paris Descartes, Sorbonne Paris Cité, 75015 Paris, France. Electronic address: tristan.mirault@aphp.fr.
authors.forename: T
authors.initials: T
authors.lastname: Mirault
authors.affiliation: Pôle cardiovasculaire rénal et métabolique, service de médecine vasculaire, hôpital européen Georges-Pompidou, hôpitaux universitaires Paris Ouest, université Paris Descartes, AP-HP, 20, rue Leblanc, 75015 Paris, France; Centre national de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, 75015 Paris, France; Inserm U970 PARCC, université Paris Descartes, Sorbonne Paris Cité, 75015 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Messas
mesh_terms: D001011:Aorta / Q000473:pathology; D001025:Aortitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D003251:Constriction, Pathologic / Q000175:diagnosis / Q000209:etiology; D018450:Disease Progression; D005260:Female; D006801:Humans; D006978:Hypertension, Renovascular / Q000175:diagnosis / Q000209:etiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000628:therapy; D013625:Takayasu Arteritis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000473:pathology / Q000628:therapy
keywords: Aortite; Aortitis; Maladie de Takayasu; Takayasu arteritis