title: Improving interfacial adhesion with epoxy matrix using hybridized carbon nanofibers containing calcium phosphate nanoparticles for bone repairing.
abstract: Hybridized carbon nanofibers containing calcium phosphate nanoparticles (CNF/CaP) were investigated as osteocompatible nanofillers for epoxy resin. The CNF/CaP was produced by electrospinning mixture solution of polyacrylonitrile and CaP precursor sol-gel, followed by preoxidation and carbonization. The continuous and long CNF/CaP was ultrasonically chopped, mixed into epoxy resin and thermo-cured. Compared to pure CNFs with similar ultrasonication treatment, the shortened CNF/CaP reinforced composites demonstrated significant enhancement in flexural properties of epoxy composites, benefiting from the improved interfacial adhesion between CNF/CaP and resin matrix. The resulting composites also displayed good biocompatibility and sustained calcium ion release, which categorized them as promising materials for bone repairing.
authors.affiliation: State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors.forename: Xukang
authors.initials: X
authors.lastname: Gao
authors.affiliation: State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors.forename: Jinle
authors.initials: J
authors.lastname: Lan
authors.affiliation: State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Jia
authors.affiliation: State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, PR China. Electronic address: caiqing@mail.buct.edu.cn.
authors.forename: Qing
authors.initials: Q
authors.lastname: Cai
authors.affiliation: State Key Laboratory of Organic-Inorganic Composites, Beijing Laboratory of Biomedical Materials, Beijing University of Chemical Technology, Beijing 100029, PR China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Yang
mesh_terms: D000818:Animals; D018786:Bone Substitutes / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry*; D002460:Cell Line; D008422:Materials Testing; D051379:Mice; D057139:Nanofibers / Q000737:chemistry*
chemical_list: D018786:Bone Substitutes; D002130:Calcium Phosphates; D002244:Carbon; C020243:calcium phosphate
keywords: Bone repairing; Calcium phosphate; Carbon nanofibers; Nanocomposites