title: Changes of volatile sulphur compounds during therapy of a case series of patients with chronic periodontitis and halitosis.
abstract: OBJECTIVE
  To assess the effect of different stages of intervention on volatile sulphur compounds (VSCs) of periodontitis patients with halitosis, before and after non-surgical periodontal therapy.
  
  
  METHODS
  This clinical trial included 18 adults with chronic periodontitis and halitosis. After initial examination, patients received oral hygiene (OH) instructions and tongue cleaner. One week later, non-surgical periodontal therapy was completed within 48 h. Measurements were at baseline, 1 week after OH, 1 and 6 weeks post therapy. These included simplified plaque index (sPlI), probing pocket depth (PPD), bleeding on probing (BoP), Winkel Tongue Coating Index (WTCI), organoleptic scores (OLSs) of nose and mouth air and VSCs.
  
  
  RESULTS
  sPlI, BoP, WTCI, OLS of the mouth air and VSCs showed significant differences (p < 0.05), even after 1 week of OH. A further significant decrease was determined 1 week after non-surgical therapy for WTCI, OLS (nose and mouth air) and methyl mercaptan concentration. A significant decrease, 6 weeks post therapy, was observed for sPlI, BoP, WTCI, PPD, OLS of the nose and mouth air and VSCs (p < 0.05).
  
  
  CONCLUSIONS
  Oral hygiene and tongue cleaning improve the OLSs of the mouth air and reduce VSCs. Periodontal therapy further improves the OLSs and reduces the concentration of VSCs.
authors.affiliation: Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Avraam
authors.initials: A
authors.lastname: Iatropoulos
authors.affiliation: Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Vasileios
authors.initials: V
authors.lastname: Panis
authors.affiliation: Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Eirini
authors.initials: E
authors.lastname: Mela
authors.affiliation: Department of Oral Diagnosis & Radiology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Theodoros
authors.initials: T
authors.lastname: Stefaniotis
authors.affiliation: Department of Periodontology, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: Phoebus N
authors.initials: PN
authors.lastname: Madianos
authors.affiliation: Department of Preventive and Community Dentistry, School of Dentistry, National and Kapodistrian University of Athens, Athens, Greece.
authors.forename: William
authors.initials: W
authors.lastname: Papaioannou
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D055113:Chronic Periodontitis / Q000188:drug therapy*; D003774:Dental Plaque Index; D005260:Female; D006209:Halitosis / Q000188:drug therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D013457:Sulfur Compounds / Q000627:therapeutic use*; D014059:Tongue
chemical_list: D013457:Sulfur Compounds
keywords: halitosis; non-surgical therapy; periodontitis; volatile sulphur compounds