title: Silver Oxide Based Nanoparticle Assisted Laser Desorption/Ionization Mass Spectrometry for the Detection of Low Molecular Weight Compounds.
abstract: A specific property of silver oxide-based nanoparticles permits the ionization of an analyte, giving rise to various applications of a smart analytical methodology. The nanoparticles (d=6.7 nm) contained an Ag2O core. The detection of several model componds (a nucleobase and two hair growth promoters) via the use of silver oxide nanoparticles is described. Adducts were produced between the target molecules and the two silver stable isotopes (Ag(107) and Ag(109)), resulting in the formation of specific signals as well as a protonated signal. Thus, it was possible to easily determine whether the given signals were correlated with the target molecule or not.
authors.affiliation: Department of Bioscience, Fukui Prefectural University.
authors.forename: Shu
authors.initials: S
authors.lastname: Taira
authors.affiliation: Biological Science Laboratories, KAO Corporation.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Taguchi
authors.affiliation: Biological Science Laboratories, KAO Corporation.
authors.forename: Reiko
authors.initials: R
authors.lastname: Fukuda
authors.affiliation: Department of Bioscience, Fukui Prefectural University.
authors.forename: Kohei
authors.initials: K
authors.lastname: Uematsu
authors.affiliation: Department of Physics, Graduate School of Engineering, Yokohama National University.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Ichiyanagi
authors.affiliation: Department of Molecular Biology and Chemistry, University of Fukui.
authors.forename: Yukie
authors.initials: Y
authors.lastname: Tanaka
authors.affiliation: Department of Molecular Biology and Chemistry, University of Fukui.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Fujii
authors.affiliation: Department of Bioscience, Fukui Prefectural University.
authors.forename: Hajime
authors.initials: H
authors.lastname: Katano
keywords: SALDI; hair growth promoters; nano-PALDI; nanoparticle; silver oxide
references.citation: Analyst. 2012 May 7;137(9):2006-10
references.pmid: 22337326
references.citation: J Am Soc Mass Spectrom. 2009 Oct;20(10):1925-32
references.pmid: 19682921
references.citation: Anal Chem. 2007 Feb 15;79(4):1626-33
references.pmid: 17297965
references.citation: Anal Sci. 2005 Aug;21(8):901-5
references.pmid: 16122158
references.citation: Biol Pharm Bull. 2008 Mar;31(3):449-53
references.pmid: 18310908
references.citation: Anal Chem. 2011 Feb 15;83(4):1370-4
references.pmid: 21261259
references.citation: Anal Chem. 2008 Oct 1;80(19):7524-33
references.pmid: 18778032
references.citation: J Nanosci Nanotechnol. 2009 Jan;9(1):169-76
references.pmid: 19441292
references.citation: Anal Chem. 2008 Jun 15;80(12):4761-6
references.pmid: 18476721
references.citation: J Am Soc Mass Spectrom. 2008 Sep;19(9):1343-6
references.pmid: 18640850
references.citation: Anal Chem. 2008 Sep 1;80(17):6796-9
references.pmid: 18671412
references.citation: Br J Dermatol. 2004 Feb;150(2):186-94
references.pmid: 14996087
references.citation: Analyst. 2013 Dec 7;138(23):7053-65
references.pmid: 24133675
references.citation: Rapid Commun Mass Spectrom. 2008 Sep;22(18):2863-72
references.pmid: 18720468