title: A Concise History of Asperger Syndrome: The Short Reign of a Troublesome Diagnosis.
abstract: First described in 1944 by Hans Asperger (1944), it was not before 1994 that Asperger Syndrome (AS) was included in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders, only to disappear in the Manual's fifth edition in 2013. During its brief existence as a diagnostic entity, AS aroused immense interest and controversy. Similar to patients with autism, AS patients show deficits in social interaction, inappropriate communication skills, and interest restriction, but also display a rich variety of subtle clinical characteristics that for many distinguish AS from autism. However, difficulties operationalising diagnostic criteria and differentiating AS from autism ultimately led to its merging into the unifying category of Autistic Spectrum Disorders. Here we briefly review the short history of this fascinating condition.
authors.affiliation: Department of Psychiatry and Mental Health, Nova Medical School/Faculdade de Ciências Médicas - Universidade Nova de LisboaLisbon, Portugal; Neuropsychiatry Unit, Champalimaud Clinical Centre, Fundação ChampalimaudLisbon, Portugal; Centro de Apoio ao Desenvolvimento Infantil - CADINCascais, Portugal; Department of Psychiatry and Mental Health, Centro Hospitalar de Lisboa OcidentalLisbon, Portugal.
authors.forename: J B
authors.initials: JB
authors.lastname: Barahona-Corrêa
authors.affiliation: Department of Physiology, Nova Medical School/Faculdade de Ciências Médicas - Universidade Nova de Lisboa Lisbon, Portugal.
authors.forename: Carlos N
authors.initials: CN
authors.lastname: Filipe
keywords: Asperger Syndrome; DSM-5; autism spectrum disorders; nosology; psychopathology
references.citation: J Autism Dev Disord. 2013 Jul;43(7):1692-700
references.pmid: 23143130
references.citation: J Child Psychol Psychiatry. 2004 Mar;45(3):421-34
references.pmid: 15055363
references.citation: J Autism Dev Disord. 2002 Aug;32(4):321-331
references.pmid: 12199137
references.citation: J Autism Dev Disord. 1989 Jun;19(2):213-25
references.pmid: 2745389
references.citation: BMC Med. 2013 Jul 31;11:175
references.pmid: 23902729
references.citation: J Child Psychol Psychiatry. 2001 Feb;42(2):227-40
references.pmid: 11280419
references.citation: J Neurosci. 2007 Oct 24;27(43):11725-35
references.pmid: 17959814
references.citation: Am J Psychiatry. 2012 Oct;169(10):1056-64
references.pmid: 23032385
references.citation: J Autism Dev Disord. 2005 Apr;35(2):145-58
references.pmid: 15909401
references.citation: J Psychiatry Neurosci. 2011 Nov;36(6):412-21
references.pmid: 21406158
references.citation: Autism Res. 2009 Oct;2(5):246-57
references.pmid: 19885834
references.citation: J Autism Dev Disord. 1998 Dec;28(6):527-33
references.pmid: 9932239
references.citation: J Am Acad Child Adolesc Psychiatry. 2012 Apr;51(4):368-83
references.pmid: 22449643
references.citation: Am J Psychiatry. 2006 Jul;163(7):1252-63
references.pmid: 16816232
references.citation: Acta Paedopsychiatr. 1968;35(4):100-36
references.pmid: 4880460
references.citation: Braz J Psychiatry. 2003 Jun;25(2):103-9
references.pmid: 12975708
references.citation: Can J Psychiatry. 2000 Oct;45(8):731-8
references.pmid: 11086556
references.citation: Arch Gen Psychiatry. 2004 Mar;61(3):291-8
references.pmid: 14993117
references.citation: Neuropharmacology. 2013 May;68:202-9
references.pmid: 22727823
references.citation: J Child Psychol Psychiatry. 2008 Dec;49(12):1287-95
references.pmid: 18673405
references.citation: J Am Acad Child Adolesc Psychiatry. 2012 Jan;51(1):28-40.e3
references.pmid: 22176937
references.citation: J Autism Dev Disord. 2010 Mar;40(3):300-16
references.pmid: 19924522
references.citation: J Autism Dev Disord. 2000 Apr;30(2):169-74
references.pmid: 10832782
references.citation: J Child Neurol. 2010 Dec;25(12):1462-7
references.pmid: 20413799
references.citation: J Child Psychol Psychiatry. 1997 Feb;38(2):247-51
references.pmid: 9232470
references.citation: Am J Psychiatry. 2010 Nov;167(11):1357-63
references.pmid: 20686188
references.citation: Res Dev Disabil. 2011 Mar-Apr;32(2):768-73
references.pmid: 21208775
references.citation: Psychol Med. 2010 Jul;40(7):1171-81
references.pmid: 19891805
references.citation: J Autism Dev Disord. 2006 Nov;36(8):1065-76
references.pmid: 16865549
references.citation: Psychol Med. 1981 Feb;11(1):115-29
references.pmid: 7208735
references.citation: Psychol Med. 2009 Nov;39(11):1885-93
references.pmid: 19356262
references.citation: J Autism Dev Disord. 2008 Apr;38(4):782-7
references.pmid: 17879152
references.citation: J Child Psychol Psychiatry. 1998 Sep;39(6):893-902
references.pmid: 9758197
references.citation: J Soc Work Disabil Rehabil. 2014;13(3):247-60
references.pmid: 24816184
references.citation: Arch Gen Psychiatry. 2011 Apr;68(4):409-18
references.pmid: 21464365
references.citation: Eur Child Adolesc Psychiatry. 2006 Aug;15(5):256-64
references.pmid: 16554961
references.citation: Brain Cogn. 2006 Jun;61(1):1-4
references.pmid: 16563588
references.citation: J Autism Dev Disord. 2014 Jul;44(7):1577-96
references.pmid: 24362849
references.citation: J Autism Dev Disord. 2005 Apr;35(2):221-34
references.pmid: 15909408
references.citation: J Neural Transm (Vienna). 2014 Sep;121(9):1129-44
references.pmid: 25059455
references.citation: J Abnorm Child Psychol. 2001 Jun;29(3):263-71
references.pmid: 11411788
references.citation: J Autism Dev Disord. 2013 Dec;43(12):2914-42
references.pmid: 23644916
references.citation: J Autism Dev Disord. 2003 Feb;33(1):3-13
references.pmid: 12708575