title: Comparative study of inorganic elements determined in whole blood from Dmd(mdx)/J mice strain by EDXRF and NAA analytical techniques.
abstract: Several diseases can be diagnosed observing the variation of specific elements concentration in body fluids. In this study the concentration of inorganic elements in blood samples of dystrophic (Dmd(mdx)/J) and C57BL/6J (control group) mice strain were determined. The results obtained from Energy Dispersive X-ray Fluorescence (EDXRF) were compared with Neutron Activation Analysis (NAA) technique. Both analytical techniques showed to be appropriate and complementary offering a new contribution for veterinary medicine as well as detailed knowledge of this pathology.
authors.affiliation: Instituto de Pesquisas Energéticas e Nucleares, IPEN - CNEN/SP, Centro de Química e Meio Ambiente, CQMA, Av. Professor Lineu Prestes 2242, 05508-000 São Paulo, SP, Brasil. Electronic address: marcelo.redigolo@usp.br.
authors.forename: M M
authors.initials: MM
authors.lastname: Redígolo
authors.affiliation: Instituto de Pesquisas Energéticas e Nucleares, IPEN - CNEN/SP, Centro de Química e Meio Ambiente, CQMA, Av. Professor Lineu Prestes 2242, 05508-000 São Paulo, SP, Brasil. Electronic address: imsato@ipen.br.
authors.forename: I M
authors.initials: IM
authors.lastname: Sato
authors.affiliation: Instituto de Pesquisas Energéticas e Nucleares, IPEN - CNEN/SP, Centro do Reator de Pesquisa - CRPq, Av. Professor Lineu Prestes 2242, 05508-000 São Paulo, SP, Brasil. Electronic address: metairon@live.com.
authors.forename: S
authors.initials: S
authors.lastname: Metairon
authors.affiliation: Instituto de Pesquisas Energéticas e Nucleares, IPEN - CNEN/SP, Centro do Reator de Pesquisa - CRPq, Av. Professor Lineu Prestes 2242, 05508-000 São Paulo, SP, Brasil. Electronic address: czamboni@ipen.br.
authors.forename: C B
authors.initials: CB
authors.lastname: Zamboni
mesh_terms: D000818:Animals; D001774:Blood Chemical Analysis / Q000379:methods*; D004195:Disease Models, Animal; D004602:Elements; D005260:Female; D007287:Inorganic Chemicals / Q000097:blood*; D008297:Male; D051379:Mice; D008810:Mice, Inbred C57BL; D018101:Mice, Inbred mdx; D020388:Muscular Dystrophy, Duchenne / Q000097:blood; D009501:Neutron Activation Analysis / Q000379:methods*; D013052:Spectrometry, X-Ray Emission / Q000379:methods*
chemical_list: D004602:Elements; D007287:Inorganic Chemicals
keywords: Animal model; DMD; Energy Dispersive X-ray Fluorescence; Neutron Activation Analysis; Whole blood