title: Characterization of SXT/R391 Integrative and Conjugative Elements in Proteus mirabilis Isolates from Food-Producing Animals in China.
abstract: SXT/R391 integrative and conjugative elements (ICEs) were detected in 8 out of 125 Proteus mirabilis isolates from food-producing animals in China. Whole-genome sequencing revealed that seven ICEs were identical to ICEPmiJpn1, carrying the cephalosporinase gene blaCMY-2. Another one, designated ICEPmiChn1, carried five resistance genes. All eight ICEs could be transferred to Escherichia coli via conjugation. The results highlight the idea that animal farms are important reservoir of the SXT/R391 ICE-containing P. mirabilis.
authors.affiliation: College of Life Science, Sichuan University, Chengdu, People's Republic of China Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China.
authors.forename: Chang-Wei
authors.initials: CW
authors.lastname: Lei
authors.affiliation: College of Life Science, Sichuan University, Chengdu, People's Republic of China Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China.
authors.forename: An-Yun
authors.initials: AY
authors.lastname: Zhang
authors.affiliation: College of Life Science, Sichuan University, Chengdu, People's Republic of China Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China whongning@163.com.
authors.forename: Hong-Ning
authors.initials: HN
authors.lastname: Wang
authors.affiliation: College of Life Science, Sichuan University, Chengdu, People's Republic of China Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China.
authors.forename: Bi-Hui
authors.initials: BH
authors.lastname: Liu
authors.affiliation: College of Life Science, Sichuan University, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China.
authors.forename: Li-Qin
authors.initials: LQ
authors.lastname: Yang
authors.affiliation: College of Life Science, Sichuan University, Chengdu, People's Republic of China Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, Chengdu, People's Republic of China Key Laboratory of Bio-resources and Eco-environment, Ministry of Education, Chengdu, People's Republic of China 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern China, Chengdu, People's Republic of China.
authors.forename: Yong-Qiang
authors.initials: YQ
authors.lastname: Yang
mesh_terms: D000818:Animals; D001426:Bacterial Proteins / Q000235:genetics; D001483:Base Sequence; D002645:Chickens; D002681:China; D003227:Conjugation, Genetic / Q000235:genetics; D004251:DNA Transposable Elements / Q000235:genetics*; D004269:DNA, Bacterial / Q000235:genetics; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D000072480:Farms; D016678:Genome; D008826:Microbial Sensitivity Tests; D011201:Poultry Diseases / Q000382:microbiology; D011513:Proteus mirabilis / Q000235:genetics* / Q000302:isolation & purification*; D017422:Sequence Analysis, DNA; D013552:Swine; D013553:Swine Diseases / Q000382:microbiology; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D001426:Bacterial Proteins; D004251:DNA Transposable Elements; D004269:DNA, Bacterial; C103022:beta-lactamase CMY-2; D001618:beta-Lactamases
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