title: Development of a Mock Extracorporeal Membrane Oxygenation Circuit to Assess Recirculation.
abstract: A limitation of veno-venous extracorporeal membrane oxygenation (VV-ECMO) is the recirculating of newly oxygenated blood back to the VV-ECMO circuit. We compared cannulation strategies for combating recirculation utilizing a mock circulation loop (MCL) with ultrasonic flow probes and pressure transducers ensuring that the MCL was run at physiological hemodynamic parameters. Mean recirculation percentages were lower (ANOVA, F = 14.25; p = 0.0001) with the Wang-Zwische dual lumen cannula (4.00 ± 1.77, n = 7) than both the femoro-jugular (15.23 ± 7.00, n = 8) and the femoro-femoral cannulation configurations (13.49 ± 1.44, n = 8).
authors.affiliation: From the *Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia; †Victor Chang Cardiac Research Institute, Darlinghurst, New South Wales, Australia; and ‡St Vincent's Hospital Heart and Lung Transplant Unit, Sydney, New South Wales, Australia.
authors.forename: Ishanth Devinda
authors.initials: ID
authors.lastname: Jayewardene
authors.forename: Ashleigh
authors.initials: A
authors.lastname: Xie
authors.forename: Arjun
authors.initials: A
authors.lastname: Iyer
authors.forename: Roger
authors.initials: R
authors.lastname: Pye
authors.forename: Kumud
authors.initials: K
authors.lastname: Dhital
mesh_terms: D001775:Blood Circulation; D002404:Catheterization / Q000379:methods; D015199:Extracorporeal Membrane Oxygenation; D006439:Hemodynamics; D006801:Humans; D014465:Ultrasonics