title: [Advances in the mechanism of mesenchymal stem cells in promoting wound healing].
abstract: Mesenchymal stem cells possess the ability of self-renewal and multiple differentiation potential, thus exert immunomodulatory effect during tissue repair. Mesenchymal stem cells can stimulate angiogenesis and promote tissue repair through transdifferentiation and secreting a variety of growth factors and cytokines. This review outlines the advances in the mechanism of mesenchymal stem cells in promoting wound healing, including alleviation of inflammatory response, induction of angiogenesis, and promotion of migration of mesenchymal stem cells to the site of tissue injury.
authors.affiliation: Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Zhu
authors.affiliation: Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China.
authors.forename: Haobo
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Burns and Plastic Surgery, the Third People's Hospital of Wuxi City, Wuxi 214041, China; Email: luguozhong@hotmail.com.
authors.forename: Guozhong
authors.initials: G
authors.lastname: Lyu
mesh_terms: D002454:Cell Differentiation; D054338:Cell Transdifferentiation; D045164:Mesenchymal Stem Cell Transplantation / Q000379:methods; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism / Q000502:physiology*; D012867:Skin / Q000166:cytology / Q000378:metabolism; D014945:Wound Healing / Q000502:physiology*