title: Effect of Tissue Adhesives on Seroma Incidence After Abdominoplasty: A Systematic Review and Meta-Analysis.
abstract: BACKGROUND
  Tissue adhesives (TAs) are widely utilized in abdominoplasty to reduce postoperative seroma. However, current literature regarding TAs in abdominoplasty is limited to small studies and the findings of single institutions.
  
  
  OBJECTIVE
  The authors reviewed the current literature regarding the effects of TAs on seroma formation and other endpoints following abdominoplasty, and summarized the types of TAs and application techniques that have been described to date.
  
  
  METHODS
  A systematic review of the Medline, Embase, Web of Science, and Cochrane databases was conducted to identify randomized controlled trials (RCTs) in which the numbers of patients who experienced seroma after abdominoplasty were indicated. The Cochrane Collaboration's tool for assessing risk of bias was applied.
  
  
  RESULTS
  Seven studies were included in a descriptive review, 5 of which were RCTs. Data from the 5 RCTs were pooled for a meta-analysis. Patients who received TAs following abdominoplasty had a similar incidence of seroma compared with patients who did not receive TAs. However, the total drainage volume was significantly lower for patients who received TAs.
  
  
  CONCLUSIONS
  There is a paucity of high-quality evidence to support the delivery of TAs to prevent seroma formation after abdominoplasty. Well-designed RCTs are needed to assess with confidence the overall effects of TAs in abdominoplasty.
  
  
  METHODS
  2 Therapeutic.
authors.affiliation: Drs Nasr and Sleilati are Assistant Professors, and Dr Jabbour and Elkhoury are Residents, Department of Plastic and Reconstructive Surgery, Hotel Dieu de France University Hospital, Beirut, Lebanon. Dr Mhawej is a Resident, Department of Otolaryngology, Hotel Dieu de France University Hospital, Beirut, Lebanon.
authors.forename: Marwan W
authors.initials: MW
authors.lastname: Nasr
authors.affiliation: Drs Nasr and Sleilati are Assistant Professors, and Dr Jabbour and Elkhoury are Residents, Department of Plastic and Reconstructive Surgery, Hotel Dieu de France University Hospital, Beirut, Lebanon. Dr Mhawej is a Resident, Department of Otolaryngology, Hotel Dieu de France University Hospital, Beirut, Lebanon.
authors.forename: Samer F
authors.initials: SF
authors.lastname: Jabbour
authors.affiliation: Drs Nasr and Sleilati are Assistant Professors, and Dr Jabbour and Elkhoury are Residents, Department of Plastic and Reconstructive Surgery, Hotel Dieu de France University Hospital, Beirut, Lebanon. Dr Mhawej is a Resident, Department of Otolaryngology, Hotel Dieu de France University Hospital, Beirut, Lebanon.
authors.forename: Rachad I
authors.initials: RI
authors.lastname: Mhawej
authors.affiliation: Drs Nasr and Sleilati are Assistant Professors, and Dr Jabbour and Elkhoury are Residents, Department of Plastic and Reconstructive Surgery, Hotel Dieu de France University Hospital, Beirut, Lebanon. Dr Mhawej is a Resident, Department of Otolaryngology, Hotel Dieu de France University Hospital, Beirut, Lebanon.
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Elkhoury
authors.affiliation: Drs Nasr and Sleilati are Assistant Professors, and Dr Jabbour and Elkhoury are Residents, Department of Plastic and Reconstructive Surgery, Hotel Dieu de France University Hospital, Beirut, Lebanon. Dr Mhawej is a Resident, Department of Otolaryngology, Hotel Dieu de France University Hospital, Beirut, Lebanon.
authors.forename: Fadi H
authors.initials: FH
authors.lastname: Sleilati
mesh_terms: D061645:Abdominoplasty / Q000009:adverse effects*; D000328:Adult; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D016017:Odds Ratio; D065840:Protective Factors; D018570:Risk Assessment; D012307:Risk Factors; D049291:Seroma / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control*; D014014:Tissue Adhesives / Q000009:adverse effects / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D014014:Tissue Adhesives