title: Sedentary lifestyle in middle-aged women is associated with severe menopausal symptoms and obesity.
abstract: The aim of the study was to evaluate the association between sedentary lifestyle and the severity of menopausal symptoms and obesity in middle-aged women.
  
  
  
  The Menopause Rating Scale, the Goldberg Anxiety and Depression Scale, and the Athens Insomnia Scale were administered to 6,079 Latin American women aged 40 to 59 years. Sedentary lifestyle was defined as fewer than three weekly, 30-minute periods of physical activity.
  
  
  
  Sedentary women had more severe menopausal symptoms (total Menopause Rating Scale score: 9.57 ± 6.71 vs 8.01 ± 6.27 points, P < 0.0001) and more depressive symptoms (Goldberg), anxiety (Goldberg), and insomnia (Athens Scale) compared with non-sedentary women. They also had greater mean waist circumference (86.2 ± 12.3 vs 84.3 ± 1.8 cm, P < 0.0001) and a higher prevalence of obesity (20.9% vs 14.3%, P < 0.0001). Logistic regression analysis showed that both obesity (odds ratio [OR] 1.52; 95% CI, 1.32-1.76) and severe menopausal symptoms (OR 1.28; 95% CI, 1.06-1.53), including insomnia and depressive mood, were positively associated with a sedentary lifestyle. Having a stable partner (OR 0.85; 95% CI, 0.76-0.96), using hormone therapy (OR 0.75; 95% CI, 0.64-0.87) and having a higher educational level (OR 0.66; 95% CI, 0.60-0.74) were negatively related to sedentary lifestyle.
  
  
  
  There was a high prevalence of sedentary lifestyle in this middle-aged Latin American female sample which was associated with more severe menopausal symptoms and obesity.
authors.affiliation: 1Universidad de Chile, Santiago de Chile, Chile 2Clínica AVANSALUD, Santiago de Chile, Chile 3Universidad Católica de Santiago de Guayaquil, Hospital Enrique C. Sotomayor, Guayaquil, Ecuador 4Instituto Nacional de Salud, Lima, Perú 5Universidad Nacional de Cuyo, Mendoza, Argentina 6Hospital de Clínicas, Buenos Aires, Argentina 7Universidad de Panamá, Panamá 8Clínica SOLCA, Machala, Ecuador 9Universidad de Ciencias Aplicadas y Ambientales, Bogotá, Colombia 10Universidad Andina del Cusco, Cusco, Perú 11UDIME, Santa Cruz de la Sierra, Bolivia 12Universidad de Cartagena, Cartagena de Indias, Colombia 13Facultad de Medicina CLAEH, Punta del Este, Uruguay 14Universidad Nacional de Rosario, Rosario, Argentina 15Atención Médica Integral para la Mujer, Naucalpan, México 16Universidad del Valle, Cali, Colombia 17Instituto de Endocrinología, Cochabamba, Bolivia 18Universidad Diego Portales, Santiago, Chile 19Universidad Central del Ecuador, Quito, Ecuador 20Universidad de Guadalajara, Gaudalajara, México 21Universidad Nacional de Asunción, Asunción, Paraguay 22Hospital Metropolitano de Santiago, Santiago de los Caballeros, República Dominicana 23Universidad El Bosque, Bogotá, Colombia.
authors.forename: Juan E
authors.initials: JE
authors.lastname: Blümel
authors.forename: Juan
authors.initials: J
authors.lastname: Fica
authors.forename: Peter
authors.initials: P
authors.lastname: Chedraui
authors.forename: Edward
authors.initials: E
authors.lastname: Mezones-Holguín
authors.forename: María C
authors.initials: MC
authors.lastname: Zuñiga
authors.forename: Silvina
authors.initials: S
authors.lastname: Witis
authors.forename: María S
authors.initials: MS
authors.lastname: Vallejo
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Tserotas
authors.forename: Hugo
authors.initials: H
authors.lastname: Sánchez
authors.forename: William
authors.initials: W
authors.lastname: Onatra
authors.forename: Eliana
authors.initials: E
authors.lastname: Ojeda
authors.forename: Desireé
authors.initials: D
authors.lastname: Mostajo
authors.forename: Alvaro
authors.initials: A
authors.lastname: Monterrosa
authors.forename: Selva
authors.initials: S
authors.lastname: Lima
authors.forename: Mabel
authors.initials: M
authors.lastname: Martino
authors.forename: José A
authors.initials: JA
authors.lastname: Hernández-Bueno
authors.forename: Gustavo
authors.initials: G
authors.lastname: Gómez
authors.forename: María T
authors.initials: MT
authors.lastname: Espinoza
authors.forename: Daniel
authors.initials: D
authors.lastname: Flores
authors.forename: Andrés
authors.initials: A
authors.lastname: Calle
authors.forename: Luz M
authors.initials: LM
authors.lastname: Bravo
authors.forename: Zully
authors.initials: Z
authors.lastname: Benítez
authors.forename: Ascanio
authors.initials: A
authors.lastname: Bencosme
authors.forename: Germán
authors.initials: G
authors.lastname: Barón
authors.forename: Sócrates
authors.initials: S
authors.lastname: Aedo
mesh_terms: D000328:Adult; D001007:Anxiety / Q000208:ethnology / Q000209:etiology; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology / Q000208:ethnology; D005260:Female; D019584:Hot Flashes / Q000453:epidemiology / Q000208:ethnology; D006801:Humans; D007843:Latin America / Q000453:epidemiology / Q000208:ethnology; D008593:Menopause / Q000208:ethnology* / Q000523:psychology; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology / Q000208:ethnology*; D015995:Prevalence; D057185:Sedentary Behavior / Q000208:ethnology*; D012720:Severity of Illness Index; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology / Q000208:ethnology