title: Severe symptomatic intracranial internal carotid artery stenosis treated with intracranial stenting: a single center study with 58 patients.
abstract: OBJECTIVE
  We aimed to investigate the safety and effectiveness of intracranial stenting in a population with severe (≥ 70%) symptomatic intracranial internal carotid artery (ICA) atherosclerotic stenosis.
  
  
  METHODS
  Fifty-eight patients with severe intracranial ICA atherosclerotic stenosis were prospectively enrolled. The baseline data, cerebral angiography, success rate, perioperative complications, clinical and imaging follow-up were prospectively analyzed.
  
  
  RESULTS
  All patients had successful intracranial stenting (100%), and the mean degree of stenosis was improved from 84.3% ± 7.5% to 23.5% ± 5.1% after the stent procedure. During the 30-day perioperative period, only one patient (1.7%) had ischemic stroke. Seven patients (12.1%) had headache and dysphoria. Thirty-six patients (62.1%) had clinical follow-up for 6-68 months after stenting. Five female patients (13.9%) had ipsilateral stroke including one death, but no disabling stroke, while three other patients (8.3%) had ipsilateral temporary ischemic attack (TIA). The recurrent stroke rate was higher in patients presenting with stroke (4/17, 23.5%) than in patients presenting with TIA (1/19, 5.3%), with no statistical significance (P = 0.33). Thirteen patients (22.4%) had imaging follow-up of 5-12 months following stenting, five of whom (38.5%) had in-stent restenosis.
  
  
  CONCLUSIONS
  Intracranial stenting for patients with intracranial ICA atherosclerotic stenosis has a low perioperative stroke rate and decent outcome on long-term follow-up, despite a relatively high in-stent restenosis rate.
authors.affiliation: Stroke Center, Henan Provincial People's Hospital, Zhengzhou University, Henan, China. litianxiaod@163.com.
authors.forename: Zi-Liang
authors.initials: ZL
authors.lastname: Wang
authors.forename: Bu-Lang
authors.initials: BL
authors.lastname: Gao
authors.forename: Tian-Xiao
authors.initials: TX
authors.lastname: Li
authors.forename: Dong-Yang
authors.initials: DY
authors.lastname: Cai
authors.forename: Liang-Fu
authors.initials: LF
authors.lastname: Zhu
authors.forename: Jiang-Yu
authors.initials: JY
authors.lastname: Xue
authors.forename: Wei-Xing
authors.initials: WX
authors.lastname: Bai
authors.forename: Zhao-Shuo
authors.initials: ZS
authors.lastname: Li
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002343:Carotid Artery, Internal / Q000473:pathology / Q000601:surgery*; D016893:Carotid Stenosis / Q000473:pathology / Q000601:surgery*; D002533:Cerebral Angiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome; D055815:Young Adult
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