title: A new epidioxy-tetracyclic triterpenoid from Poria cocos Wolf.
abstract: A new epidioxy-tetracyclic triterpenoid, 3-(2-hydroxyacetoxy)-5α, 8α-peroxydehydrotumulosic acid (10), along with nine known compounds were isolated from Poria cocos Wolf (Polyporaceae). Their structures were determined by extensive spectroscopic analyses and comparison with literature data. The cytotoxicity of these compounds against human cancer cell lines MNK-45 was evaluated by MTT method.
authors.affiliation: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , People's Republic of China.|b State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process , Lianyungang , People's Republic of China.
authors.forename: Shiping
authors.initials: S
authors.lastname: Li
authors.affiliation: c Key Laboratory of Separation Science for Analytical Chemistry , Dalian Institute of Chemical Physics, Chinese Academy of Sciences , Dalian , People's Republic of China.
authors.forename: Zhixin
authors.initials: Z
authors.lastname: Wang
authors.affiliation: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , People's Republic of China.|b State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process , Lianyungang , People's Republic of China.
authors.forename: Rui
authors.initials: R
authors.lastname: Gu
authors.affiliation: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , People's Republic of China.|b State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process , Lianyungang , People's Republic of China.
authors.forename: Yiwu
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , People's Republic of China.|b State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process , Lianyungang , People's Republic of China.
authors.forename: Wenzhe
authors.initials: W
authors.lastname: Huang
authors.affiliation: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , People's Republic of China.|b State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process , Lianyungang , People's Republic of China.
authors.forename: Zhenzhong
authors.initials: Z
authors.lastname: Wang
authors.affiliation: a Jiangsu Kanion Pharmaceutical Co. Ltd. , Lianyungang , People's Republic of China.|b State Key Laboratory of New-tech for Chinese Medicine Pharmaceutical Process , Lianyungang , People's Republic of China.
authors.forename: Wei
authors.initials: W
authors.lastname: Xiao
mesh_terms: D045744:Cell Line, Tumor; D006801:Humans; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000070660:Wolfiporia / Q000737:chemistry*
chemical_list: D014315:Triterpenes
keywords: Polyporaceae; Poria cocos Wolf; cytotoxicity; epidioxy-tetracyclic triterpenoid