title: Antithrombotic therapy in peripheral artery disease.
abstract: Antiplatelet agents are recommended for the reduction of major adverse cardiovascular events among all patients with symptomatic peripheral artery disease. However, the optimal antiplatelet regimen and duration of therapy in peripheral artery disease (PAD) remains unclear, largely due to limited and conflicting data in this patient population. This article reviews current data on antithrombotic therapy in PAD and discusses the implications of this data for current practice and future research.
authors.affiliation: VA Eastern Colorado Healthcare System and Division of Cardiology, University of Colorado, Denver, CO, USA.
authors.forename: T Raymond
authors.initials: TR
authors.lastname: Foley
authors.affiliation: VA Eastern Colorado Healthcare System and Division of Cardiology, University of Colorado, Denver, CO, USA.
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Waldo
authors.affiliation: VA Eastern Colorado Healthcare System and Division of Cardiology, University of Colorado, Denver, CO, USA ehrin.armstrong@gmail.com.
authors.forename: Ehrin J
authors.initials: EJ
authors.lastname: Armstrong
mesh_terms: D000925:Anticoagulants / Q000009:adverse effects / Q000627:therapeutic use*; D001777:Blood Coagulation / Q000187:drug effects; D016638:Critical Illness; D004359:Drug Therapy, Combination; D005343:Fibrinolytic Agents / Q000009:adverse effects / Q000627:therapeutic use*; D006470:Hemorrhage / Q000139:chemically induced; D006801:Humans; D007383:Intermittent Claudication / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D007511:Ischemia / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D058729:Peripheral Arterial Disease / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000401:mortality; D010974:Platelet Aggregation / Q000187:drug effects; D010975:Platelet Aggregation Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants; D005343:Fibrinolytic Agents; D010975:Platelet Aggregation Inhibitors
keywords: anticoagulants; arterial occlusive diseases; critical limb ischemia; intermittent claudication; peripheral artery disease; platelet aggregation inhibitors