title: 2, 3-Dimethylmaleic anhydride (3, 4-Dimethyl-2, 5-furandione): A plant derived insecticidal molecule from Colocasia esculenta var. esculenta (L.) Schott.
abstract: The phasing out of methyl bromide as a fumigant, resistance problems with phosphine and other fumigants in stored product beetles, and serious concern with human health and environmental safety have triggered the search for alternative biofumigants of plant origin. Despite the identification of a large number of plants that show insecticidal activity, and the diversity of natural products with inherent eco-friendly nature, newer biofumigants of plant origin have eluded discovery. Using a bioassay driven protocol, we have now isolated a bioactive molecule from the root stock of Colocasia esculenta (L.) and characterized it as 2, 3-dimethylmaleic anhydride (3, 4-dimethyl-2, 5-furandione) based on various physico-chemical and spectroscopic techniques (IR, (1)H NMR, (13)C NMR and Mass). The molecule proved to be an efficient biofumigant which is highly toxic to insect pests for stored grains even at very low concentration, but has no adverse effect on seed germination. We finally address the potential for this molecule to become a, effective biofumigant.
authors.affiliation: Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
authors.forename: Yallappa
authors.initials: Y
authors.lastname: Rajashekar
authors.affiliation: Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
authors.forename: Ngaihlun
authors.initials: N
authors.lastname: Tonsing
authors.affiliation: Animal Resources Programme, Institute of Bioresources and Sustainable Development, Department of Biotechnology, Govt. of India, Takyelpat, Imphal-795001, Manipur, India.
authors.forename: Tourangbam
authors.initials: T
authors.lastname: Shantibala
authors.affiliation: Department of Spice &Flavour Science, Central Food Technological Research Institute, Mysore-570020, India.
authors.forename: Javagal R
authors.initials: JR
authors.lastname: Manjunath
mesh_terms: D000812:Anhydrides / Q000737:chemistry* / Q000494:pharmacology; D000818:Animals; D001517:Coleoptera / Q000187:drug effects; D031060:Colocasia / Q000737:chemistry*; D005663:Furans / Q000737:chemistry* / Q000494:pharmacology; D018525:Germination / Q000187:drug effects; D015394:Molecular Structure; D010575:Pesticides / Q000737:chemistry* / Q000494:pharmacology; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology; D018517:Plant Roots / Q000737:chemistry
chemical_list: D000812:Anhydrides; D005663:Furans; D010575:Pesticides; D010936:Plant Extracts
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