title: Current Status of Minimally Invasive Surgery for Rectal Cancer.
abstract: Recent randomized controlled data have shown possible limitations to laparoscopic treatment of rectal cancer. The retrospective data, used as the basis for designing the trials, and which showed no problems with the technique, are discussed. The design of the randomized trials is discussed relative to the future meta-analysis of the recent data. The implications of the current findings on practice are discussed as surgeons try to adjust their practice to the new findings. The possible next steps for clinical and research innovations are put into perspective as new technology is considered to compensate for newly identified limitations in the laparoscopic treatment of rectal cancer.
authors.affiliation: Department of Surgery, Baylor University Medical Center, Dallas, TX, USA. james.fleshman@bswhealth.org.|Texas A&M University, College Station, TX, USA. james.fleshman@bswhealth.org.
authors.forename: James
authors.initials: J
authors.lastname: Fleshman
mesh_terms: D006801:Humans; D010535:Laparoscopy; D019060:Minimally Invasive Surgical Procedures; D012004:Rectal Neoplasms / Q000601:surgery*; D065287:Robotic Surgical Procedures
keywords: Laparoscopy; Rectal cancer; Robotics; Total mesorectal excision
references.citation: N Engl J Med. 2004 May 13;350(20):2050-9
references.pmid: 15141043
references.citation: Arch Surg. 1997 Jan;132(1):41-4; discussion 45
references.pmid: 9006551
references.citation: Dis Colon Rectum. 2002 Dec;45(12):1648-54
references.pmid: 12473889
references.citation: Dis Colon Rectum. 2003 Aug;46(8):1047-53
references.pmid: 12907898
references.citation: Surg Endosc. 2013 Dec;27(12):4469-77
references.pmid: 24057070
references.citation: Ann Surg. 2010 Feb;251(2):249-53
references.pmid: 20040854
references.citation: Surg Endosc. 2013 Nov;27(11):4157-63
references.pmid: 23708725
references.citation: Dis Colon Rectum. 2011 Jan;54(1):6-14
references.pmid: 21160307
references.citation: Surg Endosc. 2001 Aug;15(8):827-32
references.pmid: 11443444
references.citation: J Gastrointest Surg. 2009 Feb;13(2):275-81
references.pmid: 18941844
references.citation: Cancer Treat Rev. 2008 Oct;34(6):498-504
references.pmid: 18468803
references.citation: Cochrane Database Syst Rev. 2006 Oct 18;(4):CD005200
references.pmid: 17054246
references.citation: Recent Results Cancer Res. 2005;165:167-79
references.pmid: 15865031
references.citation: Medicine (Baltimore). 2015 Mar;94(11):e522
references.pmid: 25789947
references.citation: Ann Surg. 2005 Jul;242(1):83-91
references.pmid: 15973105
references.citation: Surg Endosc. 2010 Jul;24(7):1765
references.pmid: 20054571
references.citation: Dis Colon Rectum. 2011 Sep;54(9):1076-81
references.pmid: 21825886
references.citation: J Surg Oncol. 2014 Dec;110(8):989-96
references.pmid: 25292364
references.citation: J Clin Oncol. 2007 Jul 20;25(21):3061-8
references.pmid: 17634484
references.citation: World J Gastroenterol. 2004 Apr 15;10(8):1167-70
references.pmid: 15069719
references.citation: Cochrane Database Syst Rev. 2014 Apr 15;(4):CD005200
references.pmid: 24737031
references.citation: Ann Surg. 2008 Nov;248(5):746-50
references.pmid: 18948801
references.citation: J Gastrointest Surg. 2015 Mar;19(3):516-26
references.pmid: 25394387
references.citation: J Natl Cancer Inst. 2014 Dec 19;107(1):362
references.pmid: 25527640
references.citation: Surg Endosc. 2003 Oct;17(10):1530-5
references.pmid: 12874687
references.citation: Colorectal Dis. 2014 May;16(5):382-9
references.pmid: 24373345
references.citation: Br J Surg. 2005 Feb;92(2):225-9
references.pmid: 15609382
references.citation: Surg Endosc. 2002 Jan;16(1):7-13
references.pmid: 11961595
references.citation: Ann Surg. 2003 Mar;237(3):335-42
references.pmid: 12616116
references.citation: Surg Endosc. 2000 Jan;14(1):67-70
references.pmid: 10653240
references.citation: Clin Colon Rectal Surg. 2015 Sep;28(3):131-4
references.pmid: 26491403
references.citation: Int J Colorectal Dis. 2012 Feb;27(2):233-41
references.pmid: 21912876
references.citation: J Am Coll Surg. 2015 Aug;221(2):415-23
references.pmid: 26206640
references.citation: Br J Surg. 2003 Apr;90(4):445-51
references.pmid: 12673746
references.citation: Eur J Surg Oncol. 2014 Sep;40(9):1072-9
references.pmid: 24646748
references.citation: Lancet Oncol. 2014 Jun;15(7):767-74
references.pmid: 24837215
references.citation: JAMA. 2015 Oct 6;314(13):1356-63
references.pmid: 26441180
references.citation: Surg Endosc. 2007 Oct;21(10):1870-4
references.pmid: 17705068
references.citation: Ann Surg. 2015 Dec;262(6):1040-5
references.pmid: 25405559
references.citation: Surg Endosc. 2005 Nov;19(11):1468-74
references.pmid: 16222464
references.citation: Ann Surg. 2008 Jul;248(1):1-7
references.pmid: 18580199
references.citation: Surg Endosc. 2002 Jun;16(6):989-95
references.pmid: 12163970
references.citation: N Engl J Med. 2015 Apr 2;372(14):1324-32
references.pmid: 25830422
references.citation: Surg Innov. 2015 Aug;22(4):368-75
references.pmid: 25377216
references.citation: Am J Surg. 2013 Oct;206(4):509-17
references.pmid: 23809672
references.citation: Semin Surg Oncol. 2000 Dec;19(4):396-403
references.pmid: 11241922
references.citation: JAMA. 2015 Oct 6;314(13):1346-55
references.pmid: 26441179
references.citation: World J Surg. 1996 Mar-Apr;20(3):277-81; discussion 282
references.pmid: 8661831
references.citation: Surg Endosc. 1997 May;11(5):449-55
references.pmid: 9153173
references.citation: Dis Colon Rectum. 1999 Jul;42(7):930-9
references.pmid: 10411441
references.citation: Cochrane Database Syst Rev. 2008 Apr 16;(2):CD003432
references.pmid: 18425886
references.citation: Ann Surg Oncol. 2006 Mar;13(3):413-24
references.pmid: 16450220
references.citation: Surg Endosc. 2004 Feb;18(2):281-9
references.pmid: 14691716
references.citation: Arch Surg. 2007 Mar;142(3):298-303
references.pmid: 17372057