title: Fine-needle aspiration cytology of ovarian steroid cell tumor: A rare case report.
abstract: Steroid cell tumors (SCTs) of the ovary are a rare subgroup of sex cord tumors that account for less than 0.1% of all ovarian tumors. These tumors can produce steroids, especially testosterone, which produces symptoms such as hirsutism, amenorrhea/oligomenorrhea, and male patterned voice. For evaluation of the androgen excess, testosterone and dehydroepiandrosterone sulfate (DHEA-S) are the first laboratory tests to be measured. Abdominal ultrasound and magnetic resonance imaging (MRI) are useful radiologic imaging techniques. Although SCTs are generally benign, the risk of malignant transformation is always present. Surgical excision of tumor is the most important and hallmark treatment. The present case signifies the early preoperative diagnosis of a virilizing SCT, based on cytological features and its careful correlation with clinicopathological and radiological findings.
authors.affiliation: Department of Pathology, Government Medical College, Kota, Rajasthan, India.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Agrawal
authors.affiliation: Department of Pathology, Government Medical College, Kota, Rajasthan, India.
authors.forename: Harsh
authors.initials: H
authors.lastname: Vardhan
authors.affiliation: Department of Radio Diagnosis, Government Medical College, Kota, Rajasthan, India.
authors.forename: Singh
authors.initials: S
authors.lastname: Khokhar
authors.affiliation: Department of Pathology, Government Medical College, Kota, Rajasthan, India.
authors.forename: Naresh
authors.initials: N
authors.lastname: Rai
authors.affiliation: Department of Pathology, Government Medical College, Kota, Rajasthan, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Saxena
authors.affiliation: Department of Pathology, Government Medical College, Kota, Rajasthan, India.
authors.forename: Shahida
authors.initials: S
authors.lastname: Riyaz
keywords: Androgen; cytology; ovary; sex cord; steroid cell tumor (SCT)
references.citation: Cancer. 1967 Nov;20(11):1953-62
references.pmid: 4294036
references.citation: Clin Endocrinol (Oxf). 2011 Aug;75(2):160-4
references.pmid: 21521309
references.citation: J Clin Endocrinol Metab. 2008 Apr;93(4):1105-20
references.pmid: 18252793
references.citation: Am J Surg Pathol. 1987 Nov;11(11):835-45
references.pmid: 2823622
references.citation: Eur J Radiol. 1998 Feb;26(3):269-73
references.pmid: 9587754
references.citation: South Med J. 2000 Dec;93(12):1201-4
references.pmid: 11142457
references.citation: J Natl Med Assoc. 1976 Jan;68(1):34-8
references.pmid: 176416