title: Actin puts the squeeze on Drosophila glue secretion.
abstract: An actin filament coat promotes cargo expulsion from large exocytosing vesicles, but the mechanisms of coat formation and force generation have been poorly characterized. Elegant imaging studies of the Drosophila melanogaster salivary gland now reveal how actin and myosin are recruited, and show that myosin II forms a contractile 'cage' that facilitates exocytosis.
authors.affiliation: Institute for Integrative Biology of the Cell, Bât. 34, Avenue de la Terrasse, 9198 Gif sur Yvette cedex, France
authors.forename: Christien J
authors.initials: CJ
authors.lastname: Merrifield
mesh_terms: D000205:Actomyosin / Q000378:metabolism*; D000818:Animals; D002352:Carrier Proteins / Q000378:metabolism*; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000378:metabolism*; D005089:Exocytosis; D005967:Glue Proteins, Drosophila / Q000378:metabolism*; D008565:Membrane Proteins / Q000378:metabolism*; D012469:Salivary Glands / Q000378:metabolism*; D022142:Secretory Vesicles / Q000378:metabolism*
chemical_list: D002352:Carrier Proteins; D029721:Drosophila Proteins; D005967:Glue Proteins, Drosophila; D008565:Membrane Proteins; D000205:Actomyosin
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