title: Dietary Patterns and Their Relationship With Semen Quality.
abstract: Diet is a complex exposure variable, which calls for multiple approaches to examine the relationship between diet and disease risk. To address these issues, several authors have recently proposed studying overall dietary patterns by considering how foods and nutrients are consumed in combinations. The aim of the study was to investigate the associations between dietary patterns, semen quality parameters, and the level of reproductive hormones. The study population consisted of 336 men who attended the infertility clinic for diagnostic purposes and who had normal semen concentration of 20 to 300 mln/ml or slight oligozoospermia (semen concentration of 15-20 mln/ml). Participants were interviewed, and a semen sample was provided by them. Diet was assessed via food frequency questionnaire, and dietary patterns were identified by factor analysis. Men were classified into three groups according to scores of each dietary pattern: Western, Mixed, or Prudent. A positive association was observed between sperm concentration and Prudent dietary pattern, and level of testosterone and Prudent dietary pattern ( p = .05, p = .03, respectively). Additionally, Prudent dietary pattern was identified to decrease the DNA fragmentation index ( p = .05). The results were adjusted for sexual abstinence, age, smoking, past diseases, and alcohol consumption. Higher consumption of a Prudent dietary pattern was associated with higher sperm concentration and higher level of testosterone. Sperm chromatin structure was inversely related to higher consumption of a Prudent dietary pattern. Further research is needed to confirm these findings and extend these results to other populations.
authors.affiliation: 1 Nofer Institute of Occupational Medicine, Lodz, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Jurewicz
authors.affiliation: 2 Gameta Hospital, Rzgów, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Radwan
authors.affiliation: 1 Nofer Institute of Occupational Medicine, Lodz, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Sobala
authors.affiliation: 2 Gameta Hospital, Rzgów, Poland.
authors.forename: Paweł
authors.initials: P
authors.lastname: Radwan
authors.affiliation: 3 National Research Institute of Animal Production, Kraków-Balice, Poland.
authors.forename: Michał
authors.initials: M
authors.lastname: Bochenek
authors.affiliation: 1 Nofer Institute of Occupational Medicine, Lodz, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Hanke
mesh_terms: D002843:Chromatin / Q000737:chemistry; D003430:Cross-Sectional Studies; D004032:Diet; D006801:Humans; D008297:Male; D055101:Semen Analysis / Q000379:methods; D011795:Surveys and Questionnaires
chemical_list: D002843:Chromatin
keywords: dietary pattern; semen; sperm chromatin structure
references.citation: Syst Biol Reprod Med. 2014 Feb;60(1):43-51
references.pmid: 24074254
references.citation: Am J Clin Nutr. 1999 Feb;69(2):243-9
references.pmid: 9989687
references.citation: BMJ. 1997 Jul 5;315(7099):13-7
references.pmid: 9233319
references.citation: J Androl. 2002 Jan-Feb;23(1):25-43
references.pmid: 11780920
references.citation: Am J Physiol Renal Physiol. 2007 Aug;293(2):F594-600
references.pmid: 17537983
references.citation: Hum Reprod. 1999 Apr;14(4):1039-49
references.pmid: 10221239
references.citation: Hum Reprod. 2005 Apr;20(4):1006-12
references.pmid: 15665024
references.citation: Fertil Steril. 2010 Mar 1;93(4):1128-33
references.pmid: 19147135
references.citation: Curr Opin Lipidol. 2002 Feb;13(1):3-9
references.pmid: 11790957
references.citation: Am J Epidemiol. 1998 Jul 1 ;148(1):4-16
references.pmid: 9663397
references.citation: Am J Health Promot. 1996 Sep-Oct;11(1):42-52; discussion 52-3
references.pmid: 10163450
references.citation: Am J Clin Nutr. 2000 Oct;72(4):912-21
references.pmid: 11010931
references.citation: Fertil Steril. 2000 Mar;73(3):435-42
references.pmid: 10688992
references.citation: Am J Epidemiol. 1992 May 15;135(10 ):1114-26; discussion 1127-36
references.pmid: 1632423
references.citation: J Androl. 2004 Mar-Apr;25(2):293-302
references.pmid: 14760016
references.citation: J Androl. 2005 Jul-Aug;26(4):550-6
references.pmid: 15955895
references.citation: Hum Reprod. 2009 Jun;24(6):1304-12
references.pmid: 19228759
references.citation: Fertil Steril. 2009 Mar;91(3):812-8
references.pmid: 18314116
references.citation: Hum Reprod. 2007 Jun;22(6):1497-502
references.pmid: 17392290
references.citation: J Clin Endocrinol Metab. 2006 Sep;91(9):3324-8
references.pmid: 16787981
references.citation: Ann Intern Med. 1995 Dec 1;123(11):860-72
references.pmid: 7486470
references.citation: J Androl. 2007 Sep-Oct;28(5):638-43
references.pmid: 17522415
references.citation: Fertil Steril. 2006 Nov;86(5 Suppl 1):S202-9
references.pmid: 17055823
references.citation: Obstet Gynecol. 2007 Aug;110(2 Pt 1):378-84
references.pmid: 17666614
references.citation: Fertil Steril. 2011 Apr;95(5):1794-7
references.pmid: 21071027
references.citation: Hum Reprod. 2012 Oct;27(10):2899-907
references.pmid: 22888168
references.citation: Hum Reprod. 2008 Nov;23(11):2584-90
references.pmid: 18650557
references.citation: Hum Reprod. 2012 May;27(5):1466-74
references.pmid: 22416013
references.citation: Hum Reprod. 2008 May;23(5):1014-22
references.pmid: 18353905
references.citation: J Am Diet Assoc. 1996 Aug;96(8):785-91
references.pmid: 8683010
references.citation: Hum Reprod. 2007 Jun;22(6):1503-5
references.pmid: 17392289
references.citation: Hum Reprod. 2005 Nov;20(11):3192-7
references.pmid: 16037104