title: Graphene oxide for rapid determination of testosterone in the presence of cetyltrimethylammonium bromide in urine and blood plasma of athletes.
abstract: Electro-reduction behavior of testosterone at reduced graphene oxide/glassy carbon electrode (rGO/GCE) was studied. Cationic surfactant cetyltrimethylammonium bromide (CTAB) enhanced the reduction peak of testosterone. In borate buffer (pH5.4) CTAB-testosterone showed a reduction peak at -1.1 V (versus, Ag/AgCl). The increment of peak current obtained by deducting the reduction peak current of the CTAB-testosterone was rectilinear with testosterone concentration in the range of 2.0 to 210.0 nM, with a detection limit of 0.1 nM. The sensor was used for quantification of testosterone in biological fluids and drug.
authors.affiliation: Department of Ergonomics and Research Center for Health sciences, Hamedan University of Medical Sciences, Hamedan, Iran.
authors.forename: Rashid
authors.initials: R
authors.lastname: Heidarimoghadam
authors.affiliation: Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, Iran; Institute for Nanoscience and Nanotechnology, Sharif University of Technology, P.O. Box 14588-89694, Tehran, Iran.
authors.forename: Omid
authors.initials: O
authors.lastname: Akhavan
authors.affiliation: Department of Physics, Sharif University of Technology, P.O. Box 11155-9161, Tehran, Iran; Institute for Nanoscience and Nanotechnology, Sharif University of Technology, P.O. Box 14588-89694, Tehran, Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Ghaderi
authors.affiliation: National Research Center for Transgenic Mouse & Animal Biotechnology Division, National Institute of Genetic Engineering and Biotechnology, P.O. Box 14965-161, Tehran, Iran.
authors.forename: Ehsan
authors.initials: E
authors.lastname: Hashemi
authors.affiliation: Department of Chemistry, Hamedan Branch, Islamic Azad University, Hamedan, Iran.
authors.forename: Seyede Shima
authors.initials: SS
authors.lastname: Mortazavi
authors.affiliation: Department of Chemistry, Hamedan Branch, Islamic Azad University, Hamedan, Iran. Electronic address: a.farmany@usa.com.
authors.forename: Abbas
authors.initials: A
authors.lastname: Farmany
mesh_terms: D056352:Athletes; D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry*; D005260:Female; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D008297:Male; D012680:Sensitivity and Specificity; D013739:Testosterone / Q000097:blood* / Q000652:urine*
chemical_list: D002593:Cetrimonium Compounds; D013739:Testosterone; D006108:Graphite; D000077286:Cetrimonium
keywords: Biological fluids; Cetyltrimethylammonium bromide; Graphene; Testosterone