title: Sensitive Detection of Aromatic Hydrophobic Compounds in Water and Perfluorooctane Sulfonate in Human Serum by Surface-Assisted Laser Desorption/Ionization Mass Spectrometry (SALDI-MS) with Amine Functionalized Graphene-Coated Cobalt Nanoparticles.
abstract: In this article, we describe the application of surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) with the use of amine functionalized graphene-coated cobalt nanoparticles (CoC-NH2 nanoparticles) to analyse aromatic hydrophobic compounds that are known environmental contaminants, including polycyclic aromatic hydrocarbons (PAHs) and pentachlorophenol (PCP). Our results demonstrated that SALDI-MS can detect PCP, anthracene, and pyrene in water. In particular, the CoC-NH2 nanoparticles proved to be an efficient means of capturing PCP in water because of the high adsorption capacity of the nanoparticles for PCP, which resulted in a detectability of 100 ppt. Furthermore, the CoC-NH2 nanoparticles also functioned as an adsorbent for solid-phase extraction of perfluorooctane sulfonate (PFOS) from human serum, displaying good performance with a detectability of 10 ppb by SALDI-MS.
authors.affiliation: Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Nakai
authors.affiliation: Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University.
authors.forename: Hideya
authors.initials: H
authors.lastname: Kawasaki
authors.affiliation: Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University; Osaka City Institute of Public Health and Environmental Sciences.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yamamoto
authors.affiliation: Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University.
authors.forename: Ryuichi
authors.initials: R
authors.lastname: Arakawa
authors.affiliation: Department of Chemistry and Applied Biosciences ETH Zurich.
authors.forename: Robert N
authors.initials: RN
authors.lastname: Grass
authors.affiliation: Department of Chemistry and Applied Biosciences ETH Zurich.
authors.forename: Wendelin J
authors.initials: WJ
authors.lastname: Stark
keywords: SALDI; graphene; magnetic nanoparticles; pentachlorophenol (PCP); polycyclic aromatic hydrocarbons (PAHs); polyfluorinated compounds (PFCs)
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