title: Vertigo by Breast Cancer Metastasis 33 Years after Treatment.
abstract: A 76-year-old woman complained of vertigo for two years. She manifested left deafness, loss of caloric response, and right-beaten nystagmus. An imaging study revealed a tumorous lesion located from the clivus to the left temporal bone with inner ear destruction. A tumor biopsy was performed endonasally and the patient was diagnosed with adenocarcinoma mimicking breast cancer. She had undergone surgery for breast cancer 33 years previously, and the current biopsy specimen showed identical pathology. Breast cancer may metastasize to the skull base; however, metastasis 33 years after surgery is very rare.
authors.affiliation: Department of Otolaryngology, Tokyo Medical and Dental University, Japan.
authors.forename: Atsunobu
authors.initials: A
authors.lastname: Tsunoda
authors.forename: Yoji
authors.initials: Y
authors.lastname: Tanaka
authors.forename: Takanobu
authors.initials: T
authors.lastname: Sato
authors.forename: Susumu
authors.initials: S
authors.lastname: Kirimura
authors.forename: Ken
authors.initials: K
authors.lastname: Kitamura
mesh_terms: D000230:Adenocarcinoma / Q000150:complications / Q000556:secondary* / Q000628:therapy; D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000627:therapeutic use; D001706:Biopsy; D001943:Breast Neoplasms / Q000150:complications / Q000473:pathology* / Q000628:therapy; D005260:Female; D006801:Humans; D009759:Nystagmus, Pathologic / Q000209:etiology* / Q000473:pathology; D012074:Remission Induction; D012888:Skull Neoplasms / Q000150:complications / Q000556:secondary* / Q000628:therapy; D013629:Tamoxifen / Q000627:therapeutic use; D013701:Temporal Bone / Q000473:pathology*; D016896:Treatment Outcome; D014717:Vertigo / Q000209:etiology* / Q000473:pathology
chemical_list: D018931:Antineoplastic Agents, Hormonal; D013629:Tamoxifen