title: Mast cell differentiation: still open questions?
abstract: In this issue of Blood, Dahlin et al report on a minor circulating human mast cell (MC) progenitor cell population (lineage-negative [Lin−]/CD34hi/CD117int/hi/high-affinity immunoglobulin E receptor-positive [FcεRI+]), with an immature MC-like appearance, which is present in the peripheral blood (PB) of healthy individuals and of asthma subjects well controlled by treatment or with reduced lung function.
authors.affiliation: ECOLE NORMALE SUPERIEURE DE CACHAN.
authors.forename: Michel
authors.identifier: http://orcid.org/0000-0001-6714-7478
authors.initials: M
authors.lastname: Arock
mesh_terms: D018952:Antigens, CD34 / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008407:Mast Cells / Q000166:cytology*; D019009:Proto-Oncogene Proteins c-kit / Q000032:analysis*; D017455:Receptors, IgE / Q000032:analysis*; D013234:Stem Cells / Q000166:cytology*
chemical_list: D018952:Antigens, CD34; D017455:Receptors, IgE; D019009:Proto-Oncogene Proteins c-kit