title: Psychological interventions to improve psychological well-being in people with dementia or mild cognitive impairment: systematic review and meta-analysis protocol.
abstract: BACKGROUND
  Dementia and mild cognitive impairment are associated with an increased risk of depression, anxiety, psychological distress and poor mental health-related quality of life. However, there is a lack of research examining the evidence base for psychological interventions targeting general psychological well-being within this population. Furthermore, there is little research relating to the design of randomised controlled trials examining psychological interventions for dementia and mild cognitive impairment, such as effective recruitment techniques, trial eligibility and appropriate comparators.
  
  
  METHODS
  Systematic review of electronic databases (CINAHL; EMBASE; PsychInfo; MEDLINE; ASSIA and CENTRAL), supplemented by expert contact, reference and citation checking, and grey literature searches. Published and unpublished studies will be eligible for inclusion with no limitations placed on year of publication. Primary outcomes of interest will be standardised measurements of depression, anxiety, psychological distress or mental health-related quality of life. Eligibility and randomisation proportions will be calculated as secondary outcomes. If data permits, meta-analytical techniques will examine: (1) overall effectiveness of psychological interventions for people with dementia or mild cognitive impairment in relation to outcomes of depression, anxiety, psychological distress or mental health-related quality of life; (2) clinical and methodological moderators associated with effectiveness; (3) proportions eligible, recruited and randomised.
  
  
  BACKGROUND
  Ethical approval is not required for the present systematic review. Results will inform the design of a feasibility study examining a new psychological intervention for people with dementia and depression, with dissemination through publication in peer-reviewed journals and presentations at relevant conferences.
  
  
  BACKGROUND
  CRD42015025177.
authors.affiliation: Clinical Education Development and Research (CEDAR) Group, Psychology: College of Life and Environmental Sciences, University of Exeter, Exeter, UK Mental Health Research Group, University of Exeter Medical School, University of Exeter, Exeter, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Farrand
authors.affiliation: NIHR PenCLAHRC, Health Statistics Group, University of Exeter Medical School, University of Exeter, Exeter, UK.
authors.forename: Justin
authors.initials: J
authors.lastname: Matthews
authors.affiliation: Mental Health Research Group, University of Exeter Medical School, University of Exeter, Exeter, UK.
authors.forename: Chris
authors.initials: C
authors.lastname: Dickens
authors.affiliation: Clinical Education Development and Research (CEDAR) Group, Psychology: College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
authors.forename: Martin
authors.initials: M
authors.lastname: Anderson
authors.affiliation: Clinical Education Development and Research (CEDAR) Group, Psychology: College of Life and Environmental Sciences, University of Exeter, Exeter, UK.
authors.forename: Joanne
authors.initials: J
authors.lastname: Woodford
mesh_terms: D001007:Anxiety / Q000209:etiology / Q000628:therapy*; D002985:Clinical Protocols; D060825:Cognitive Dysfunction / Q000523:psychology*; D003704:Dementia / Q000523:psychology*; D003863:Depression / Q000209:etiology / Q000628:therapy*; D006801:Humans; D008603:Mental Health; D011613:Psychotherapy / Q000379:methods*; D011788:Quality of Life; D000078202:Systematic Reviews as Topic; D015201:Meta-Analysis as Topic
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