title: Consolidating and Exploring Antibiotic Resistance Gene Data Resources.
abstract: The unrestricted use of antibiotics has resulted in rapid acquisition of antibiotic resistance (AR) and spread of multidrug-resistant (MDR) bacterial pathogens. With the advent of next-generation sequencing technologies and their application in understanding MDR pathogen dynamics, it has become imperative to unify AR gene data resources for easy accessibility for researchers. However, due to the absence of a centralized platform for AR gene resources, availability, consistency, and accuracy of information vary considerably across different databases. In this article, we explore existing AR gene data resources in order to make them more visible to the clinical microbiology community, to identify their limitations, and to propose potential solutions.
authors.affiliation: Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium.
authors.forename: Basil Britto
authors.initials: BB
authors.lastname: Xavier
authors.affiliation: Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium.
authors.forename: Anupam J
authors.initials: AJ
authors.lastname: Das
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, United Kingdom.
authors.forename: Guy
authors.initials: G
authors.lastname: Cochrane
authors.affiliation: Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium.
authors.forename: Sandra
authors.initials: S
authors.lastname: De Ganck
authors.affiliation: Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium Laboratory of Molecular Pathology, Cell Biology and Histology, Faculty of Medicine and Health Sciences, Universiteit Antwerpen, Antwerp, Belgium.
authors.forename: Samir
authors.initials: S
authors.lastname: Kumar-Singh
authors.affiliation: National Food Institute, Technical University of Denmark, Lyngby, Denmark.
authors.forename: Frank Møller
authors.initials: FM
authors.lastname: Aarestrup
authors.affiliation: Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium.
authors.forename: Herman
authors.initials: H
authors.lastname: Goossens
authors.affiliation: Laboratory of Medical Microbiology, Vaccine & Infectious Disease Institute, Universiteit Antwerpen, Antwerp, Belgium surbhi.malhotra@uantwerpen.be.
authors.forename: Surbhi
authors.initials: S
authors.lastname: Malhotra-Kumar
mesh_terms: D000818:Animals; D019295:Computational Biology / Q000379:methods; D030541:Databases, Genetic; D024881:Drug Resistance, Bacterial; D005798:Genes, Bacterial; D006801:Humans; D008826:Microbial Sensitivity Tests / Q000379:methods
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