title: Transcellular route as the most probable explanation for the presence of plasminogen in mammal׳s milk.
abstract: Paracellular and transcellular route of passage of several milk metabolites, albumin, lactic acid dehydrogenase and plasminogen from the systemic circulation to milk is considered. The shortcoming of prevalence views considering paracellular leakage as the most probable explanation is highlighted. A detailed discussion explaining why transcellular route is the most probable explanation for the presence of plasminogen in milk is presented.
authors.affiliation: Nissim Silanikove, Agricultural Research Organisation, Institute of Animal Science, Biology of Lactation Laboratory, PO Box 6, Bet Dagan 50250, Israel. Electronic address: nsilanik@agri.huji.ac.il.
authors.forename: Nissim
authors.initials: N
authors.lastname: Silanikove
mesh_terms: D000818:Animals; D008322:Mammals; D008892:Milk / Q000378:metabolism*; D008894:Milk Proteins / Q000378:metabolism*; D010958:Plasminogen / Q000378:metabolism*
chemical_list: D008894:Milk Proteins; D010958:Plasminogen
keywords: Milk; Paracellular transcellular; Plasmin; Plasminogen