title: Colorimetric detection of bisphenol A based on unmodified aptamer and cationic polymer aggregated gold nanoparticles.
abstract: In this study, a colorimetric method was exploited to detect bisphenol A (BPA) based on BPA-specific aptamer and cationic polymer-induced aggregation of gold nanoparticles (AuNPs). The principle of this assay is very classical. The aggregation of AuNPs was induced by the concentration of cationic polymer, which is controlled by specific recognition of aptamer with BPA and the reaction of aptamer and cationic polymer forming "duplex" structure. This method enables colorimetric detection of BPA with selectivity and a detection limit of 1.50 nM. In addition, this colorimetric method was successfully used to determine spiked BPA in tap water and river water samples.
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
authors.forename: Dongwei
authors.initials: D
authors.lastname: Zhang
authors.affiliation: School of Agriculture and Biology and Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, and Bor S. Luh Food Safety Research Center, Shanghai Jiao Tong University, Shanghai 200240, China; Department of Management, Shanghai Sanda College, Shanghai 201209, China.
authors.forename: Jiayi
authors.initials: J
authors.lastname: Yang
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Ye
authors.affiliation: School of Agriculture and Biology and Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, and Bor S. Luh Food Safety Research Center, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Lurong
authors.initials: L
authors.lastname: Xu
authors.affiliation: School of Agriculture and Biology and Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, and Bor S. Luh Food Safety Research Center, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Hanchu
authors.initials: H
authors.lastname: Xu
authors.affiliation: School of Agriculture and Biology and Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, and Bor S. Luh Food Safety Research Center, Shanghai Jiao Tong University, Shanghai 200240, China.
authors.forename: Shenshan
authors.initials: S
authors.lastname: Zhan
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China.
authors.forename: Bing
authors.initials: B
authors.lastname: Xia
authors.affiliation: School of Chemical and Environmental Engineering, Shanghai Institute of Technology, Shanghai 201418, China; School of Agriculture and Biology and Key Laboratory of Urban Agriculture (South), Ministry of Agriculture, and Bor S. Luh Food Safety Research Center, Shanghai Jiao Tong University, Shanghai 200240, China. Electronic address: zjuwlm@163.com.
authors.forename: Lumei
authors.initials: L
authors.lastname: Wang
mesh_terms: D052157:Aptamers, Nucleotide / Q000737:chemistry*; D001559:Benzhydryl Compounds / Q000032:analysis*; D002412:Cations / Q000737:chemistry; D003124:Colorimetry; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D010636:Phenols / Q000032:analysis*; D011108:Polymers / Q000737:chemistry*; D000098826:Bisphenol A Compounds
chemical_list: D052157:Aptamers, Nucleotide; D001559:Benzhydryl Compounds; D002412:Cations; D006046:Gold; D010636:Phenols; D011108:Polymers; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Biosensor; Bisphenol A; Cationic polymer; Colorimetry; Gold nanoparticles