title: Giant Cell Tumour of Soft Tissue in Neck: An Uncommon Tumour in an Uncommon Location.
abstract: Giant cell tumour of soft tissue is an extremely rare tumour. It is thought to be the soft tissue counterpart of giant cell tumours of the bone due to its histological and immunohistochemical resemblances. Almost 80% of these tumours occur in upper and lower extremities; neck is a very rare location. Here we describe a case of primary soft tissue giant cell tumour in right submandibular region. A 35-year-old male patient presented with a swelling in right submandibular area. FNAC suggested a benign soft tissue neoplasm, comprising of spindle cells and multinucleated giant cells. Histopathology of resected specimen showed spindle cell tumour with intricately mixed giant cells, consistent with a primary giant cell tumour of soft tissue. Giant cells were CD 68 positive. Giant cell tumour of soft tissue is benign tumour, though very rarely can show features of malignancy. We present this case for its rarity and morphological overlap with other soft tissue neoplasms containing giant cells.
authors.affiliation: Junior Resident III, Department of Pathology, N:L Ratan Sircar, Medical College & Hospital , Kolkata, India .
authors.forename: Abhishek
authors.initials: A
authors.lastname: Bandyopadhyay
authors.affiliation: Demonstrator, Department of Pathology, N:L Ratan Sircar, Medical College & Hospital , Kolkata, India .
authors.forename: Binny
authors.initials: B
authors.lastname: Khandakar
authors.affiliation: Demonstrator, Department of Pathology, N:L Ratan Sircar, Medical College & Hospital , Kolkata, India .
authors.forename: Sripurna
authors.initials: S
authors.lastname: Medda
authors.affiliation: Demonstrator, Department of Pathology, N:L Ratan Sircar, Medical College & Hospital , Kolkata, India .
authors.forename: Soumit
authors.initials: S
authors.lastname: Dey
authors.affiliation: Professor, Department of Pathology, Malda Medical College, Hospital , Malda, India .
authors.forename: Prabir Chandra
authors.initials: PC
authors.lastname: Paul
keywords: CD68; GCT-ST; Head-Neck; Spindle Cells
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