title: [Metastatic bronchial carcinoid tumors].
abstract: Bronchial carcinoids are uncommon pulmonary neoplasms and represent 1 to 2 % of all lung tumors. In early stage of disease, the mainstay and only curative treatment is surgery. Bronchial carcinoids are generally regarded as low-grade carcinomas and metastatic dissemination is unusual. The management of the metastatic stage is not currently standardized due to a lack of relevant studies. As bronchial carcinoids and in particular their metastatic forms are rare, we apply treatment strategies that have been evaluated in gastrointestinal and pancreatic neuroendocrine tumors. However, bronchial carcinoids have their own characteristic. A specific therapeutic feature of these metastatic tumors is that they require a dual approach: both anti-secretory for the carcinoid syndrome, and anti-tumoral.
authors.affiliation: Service de pneumologie aiguë spécialisée et cancérologie thoracique, centre hospitalier Lyon-Sud, hospices civils de Lyon, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France; Université Lyon 1, 69100 Villeurbanne, France. Electronic address: karima.bk@hotmail.fr.
authors.forename: K
authors.initials: K
authors.lastname: Bouledrak
authors.affiliation: Université Lyon 1, 69100 Villeurbanne, France; Fédération des spécialités digestives, hôpital Édouard-Herriot, hospices civils de Lyon, 69003 Lyon, France; Inserm, UMR 1052 CNRS UMR 5286, 69008 Lyon cedex, France.
authors.forename: T
authors.initials: T
authors.lastname: Walter
authors.affiliation: Service de pneumologie aiguë spécialisée et cancérologie thoracique, centre hospitalier Lyon-Sud, hospices civils de Lyon, 165, chemin du Grand-Revoyet, 69495 Pierre-Bénite, France; Université Lyon 1, 69100 Villeurbanne, France.
authors.forename: P J
authors.initials: PJ
authors.lastname: Souquet
authors.affiliation: Université Lyon 1, 69100 Villeurbanne, France; Fédération des spécialités digestives, hôpital Édouard-Herriot, hospices civils de Lyon, 69003 Lyon, France; Inserm, UMR 1052 CNRS UMR 5286, 69008 Lyon cedex, France.
authors.forename: C
authors.initials: C
authors.lastname: Lombard-Bohas
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis / Q000097:blood; D001984:Bronchial Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D002276:Carcinoid Tumor / Q000453:epidemiology / Q000473:pathology / Q000628:therapy; D003952:Diagnostic Imaging / Q000379:methods; D006801:Humans; D009362:Neoplasm Metastasis
chemical_list: D014408:Biomarkers, Tumor
keywords: Anatomopathologie; Anatomopathology; Bronchial carcinoids; Carcinoid syndrome; Carcinoïdes bronchiques; Chemotherapy; Chimiothérapie; Metastatic stage; Stade métastatique; Syndrome carcinoïde; Traitements; Treatment