title: Pregnancy During Recovery from Hematopoietic Stem Cell Transplant for Mycosis Fungoides.
abstract: We report a case of spontaneous pregnancy with subsequent full-term live birth following hematopoietic stem cell transplantation (HSCT) for mycosis fungoides in a 24-year-old nulligravida with 4 years of prior infertility due to primary ovarian insufficiency. Four months post-transplant, the patient was found to be 10 weeks pregnant. Her pregnancy was complicated by first trimester fetal exposure to mycophenolate mofetil (pregnancy category D), delayed-onset acute gastrointestinal graft-versus-host disease, and multiple systemic infections. This report highlights the importance of discussing potential fertility outcomes in patients undergoing HSCT, including the necessity for adequate contraception post-transplant, even in the setting of previous infertility.
authors.affiliation: 1 University of California , San Diego School of Medicine, La Jolla, California.
authors.forename: Zena C
authors.initials: ZC
authors.lastname: Kharsa
authors.affiliation: 2 Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Stanford University Medical Center , Stanford, California.
authors.forename: Stephanie L F
authors.initials: SL
authors.lastname: Gustin
authors.affiliation: 2 Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, Stanford University Medical Center , Stanford, California.|3 Stanford Fertility and Reproductive Medicine Center , Palo Alto, California.
authors.forename: Lynn M
authors.initials: LM
authors.lastname: Westphal
keywords: infertility; lymphoma; oncofertility; stem cell transplant