title: Sweet Syndrome: A Review and Update.
abstract: Sweet syndrome is the most representative entity of febrile neutrophilic dermatoses. It typically presents in patients with pirexya, neutrophilia, painful tender erytomatous papules, nodules and plaques often distributed asymmetrically. Frequent sites include the face, neck and upper extremities. Affected sites show a characteristical neutrophilic infiltrate in the upper dermis. Its etiology remains elucidated, but it seems that can be mediated by a hypersensitivity reaction in which cytokines, followed by infiltration of neutrophils, may be involved. Systemic corticosteroids are the first-line of treatment in most cases. We present a concise review of the pathogenesis, classification, diagnosis and treatment update of this entity.
authors.affiliation: Department of Dermatology, "Dr. José E. González" University Hospital of the School of Medicine of the "Universidad Autónoma de Nuevo León", Monterrey, Mexico.
authors.forename: C D
authors.initials: CD
authors.lastname: Villarreal-Villarreal
authors.affiliation: Department of Dermatology, "Dr. José E. González" University Hospital of the School of Medicine of the "Universidad Autónoma de Nuevo León", Monterrey, Mexico.
authors.forename: J
authors.initials: J
authors.lastname: Ocampo-Candiani
authors.affiliation: Department of Dermatology, "Dr. José E. González" University Hospital of the School of Medicine of the "Universidad Autónoma de Nuevo León", Monterrey, Mexico. Electronic address: dravillarrealmtz@yahoo.com.mx.
authors.forename: A
authors.initials: A
authors.lastname: Villarreal-Martínez
mesh_terms: D000465:Algorithms; D006801:Humans; D016463:Sweet Syndrome / Q000175:diagnosis / Q000628:therapy
keywords: Dermatosis neutrofílicas; Drug-induced Sweet's syndrome; Malignancy-associated Sweet's syndrome; Neutrophilic dermatoses; Sweet syndrome; Síndrome de Sweet; Síndrome de Sweet asociado a malignidad; Síndrome de Sweet inducido por medicamentos