title: Rate of progression of total, upper, and lower visual field defects in patients with open-angle glaucoma and high myopia.
abstract: OBJECTIVE
  We evaluated the rate of progression of total, upper, and lower visual field defects in patients with treated primary open-angle glaucoma (POAG) with high myopia (HM).
  
  
  METHODS
  Seventy eyes of 70 POAG patients with HM [≤-8 diopters (D)] were examined. The mean deviation (MD) slope and the upper and lower total deviation (upper TD, lower TD) slopes of the Humphrey Field Analyzer were calculated in patients with high-tension glaucoma (HTG) (>21 mmHg) versus normal-tension glaucoma (NTG) (≤21 mmHg). The mean age of all the patients (29 eyes with HTG and 41 eyes with NTG) was 48.5 ± 9.6 years. The MD slope, and upper and lower TD slopes of the HM group were compared to those of the non-HM group (NHM) (>-8 D) selected from 544 eyes in 325 age-matched POAG patients. In all, 70 eyes with HM and NHM were examined.
  
  
  RESULTS
  The mean MD slope was -0.33 ± 0.33 dB/year in the HM, and -0.38 ± 0.49 dB/year in the NHM. There were no statistical differences between the HM and NHM (p = 0.9565). In the comparison of HTG versus NTG patients in both groups, the MD slope, and upper and lower TD slopes were similar.
  
  
  CONCLUSIONS
  The rate of progression of total, upper, and lower visual field defects was similar among patients with HM and NHM. Although HM is a risk factor for the onset of glaucoma, HM may not be a risk factor for progression of visual field defects as assessed by the progression rate under treatment.
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan. takaiko0706@gmail.com.
authors.forename: Takaiko
authors.initials: T
authors.lastname: Yoshino
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan.
authors.forename: Takeo
authors.initials: T
authors.lastname: Fukuchi
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Togano
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Sakaue
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan.
authors.forename: Masaaki
authors.initials: M
authors.lastname: Seki
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Tanaka
authors.affiliation: Division of Ophthalmology and Visual Science, Graduate School of Medical and Dental Science, Niigata University, 1-757 Asahimachi-dori Niigata, Niigata, 951-8510, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Ueda
mesh_terms: D000328:Adult; D018450:Disease Progression; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D057066:Low Tension Glaucoma / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D047728:Myopia, Degenerative / Q000175:diagnosis* / Q000503:physiopathology; D012189:Retrospective Studies; D012307:Risk Factors; D014065:Tonometry, Ocular; D014786:Vision Disorders / Q000175:diagnosis* / Q000503:physiopathology; D058609:Visual Field Tests; D014794:Visual Fields / Q000502:physiology*
keywords: High myopia; Mean deviation slope; Primary open-angle glaucoma; Progressive rate; Total deviation slope
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