title: Cranial irradiation significantly reduces beta amyloid plaques in the brain and improves cognition in a murine model of Alzheimer's Disease (AD).
authors.affiliation: Department of Radiation Oncology, William Beaumont Hospital, 3811 W. Thirteen Mile Rd, 105-RI, Royal Oak, MI 48073, USA. Electronic address: brian.marples@beaumont.edu.
authors.forename: Brian
authors.initials: B
authors.lastname: Marples
authors.affiliation: Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, USA.
authors.forename: Mackenzie
authors.initials: M
authors.lastname: McGee
authors.affiliation: Department of Psychology, Wayne State University, Detroit, USA.
authors.forename: Sean
authors.initials: S
authors.lastname: Callan
authors.affiliation: Department of Psychology, Wayne State University, Detroit, USA.
authors.forename: Scott E
authors.initials: SE
authors.lastname: Bowen
authors.affiliation: Beaumont BioBank and Erb Family Core Molecular Laboratories, William Beaumont Hospital, USA.
authors.forename: Bryan J
authors.initials: BJ
authors.lastname: Thibodeau
authors.affiliation: Beaumont Neurosurgery, William Beaumont Hospital and Michigan Head and Spine Institute, USA.
authors.forename: Daniel B
authors.initials: DB
authors.lastname: Michael
authors.affiliation: Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, USA.
authors.forename: George D
authors.initials: GD
authors.lastname: Wilson
authors.affiliation: Division of Geriatric Medicine, William Beaumont Hospital and Department of Internal Medicine, Oakland University-William Beaumont School of Medicine, Detroit, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Maddens
authors.affiliation: Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, USA.
authors.forename: James
authors.initials: J
authors.lastname: Fontanesi
authors.affiliation: Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, USA.
authors.forename: Alvaro A
authors.initials: AA
authors.lastname: Martinez
mesh_terms: D000544:Alzheimer Disease; D000818:Animals; D001921:Brain; D003071:Cognition; D016371:Cranial Irradiation; D004195:Disease Models, Animal; D051379:Mice; D008822:Mice, Transgenic; D058225:Plaque, Amyloid