title: [SLEEP DISORDERED BREATHING AND EPILEPSY: RELATIONSHIPS AND THERAPEUTIC CONSIDERATIONS].
abstract: The importance of the sleep related breathing disorders (obstructive sleep apnea syndrome, central sleep apnea, and Cheyne-Stokes breathing) in the pathophysiology crebro- and cardiovascular disorders is well known. The relationship of sleep related breathing abnormalities and epilepsy is also important but underestimated in the daily practice. The relation is bidirectional. The breathing abnormalities in sleep may play important role in generating epileptic seizure, but the adverse effect of seizure and antiepileptic therapy (generation of apneas and hypopneas) may worsen the seizure control. The effect of new therapies (vagal nerve and deep brain stimulation) on the sleep architecture and sleep disordered breathing must be examined and discussed. Here we present a brief case of epileptic patient with deep brain stimulation therapy on sleep as well. The examination of the sleep related breathing abnormalities in epilepsy patient may help improve the effectiveness of antiepileptic therapy.
authors.forename: Béla
authors.initials: B
authors.lastname: Faludi
authors.forename: Beáta
authors.initials: B
authors.lastname: Bóné
authors.forename: Sámuel
authors.initials: S
authors.lastname: Komoly
authors.forename: József
authors.initials: J
authors.lastname: Janszky
mesh_terms: D000328:Adult; D000927:Anticonvulsants / Q000008:administration & dosage / Q000009:adverse effects; D001569:Benzodiazepines / Q000008:administration & dosage / Q000009:adverse effects; D002639:Cheyne-Stokes Respiration / Q000175:diagnosis* / Q000209:etiology / Q000503:physiopathology; D045422:Continuous Positive Airway Pressure; D003645:Death, Sudden / Q000209:etiology; D046690:Deep Brain Stimulation / Q000009:adverse effects*; D003937:Diagnosis, Differential; D004827:Epilepsy / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006801:Humans; D009290:Narcolepsy / Q000209:etiology; D017286:Polysomnography; D012148:Restless Legs Syndrome / Q000175:diagnosis* / Q000209:etiology; D012307:Risk Factors; D012640:Seizures / Q000150:complications / Q000175:diagnosis; D012890:Sleep / Q000187:drug effects; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000628:therapy; D012893:Sleep Wake Disorders / Q000209:etiology* / Q000503:physiopathology / Q000523:psychology; D012895:Sleep, REM / Q000187:drug effects
chemical_list: D000927:Anticonvulsants; D001569:Benzodiazepines