title: A facile three-step total synthesis of tanshinone I.
abstract: A facile synthetic approach for total synthesis of tanshinone I has been accomplished. The key precursor is a novel compound, epoxy phenanthraquinone. And this synthesis of tanshinone I is achieved in only three simple stages, which include Diels-Alder reaction, Δ(2)-Weitz-Scheffer-type epoxidation, and Feist-Bénary reaction from commercially available styrene.
authors.affiliation: a Department of Chemistry , University of Science and Technology Beijing , Beijing 100083 , China.
authors.forename: Han-Rui
authors.initials: HR
authors.lastname: Yang
authors.affiliation: a Department of Chemistry , University of Science and Technology Beijing , Beijing 100083 , China.
authors.forename: Jie-Jie
authors.initials: JJ
authors.lastname: Wang
authors.affiliation: a Department of Chemistry , University of Science and Technology Beijing , Beijing 100083 , China.
authors.forename: Peng-Peng
authors.initials: PP
authors.lastname: Shao
authors.affiliation: a Department of Chemistry , University of Science and Technology Beijing , Beijing 100083 , China.
authors.forename: Si-Yi
authors.initials: SY
authors.lastname: Yuan
authors.affiliation: a Department of Chemistry , University of Science and Technology Beijing , Beijing 100083 , China.
authors.forename: Xu-Qin
authors.initials: XQ
authors.lastname: Li
mesh_terms: D045784:Abietanes / Q000138:chemical synthesis* / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D027544:Salvia / Q000737:chemistry; D013237:Stereoisomerism; D020058:Styrene / Q000737:chemistry*
chemical_list: D045784:Abietanes; C021751:tanshinone; D020058:Styrene
keywords: Diels–Alder reaction; Feist–Bénary reaction; Tanshinone I; peroxidation; total synthesis