title: Mobile genetic elements: in silico, in vitro, in vivo.
abstract: Mobile genetic elements (MGEs), also called transposable elements (TEs), represent universal components of most genomes and are intimately involved in nearly all aspects of genome organization, function and evolution. However, there is currently a gap between the fast pace of TE discovery in silico, driven by the exponential growth of comparative genomic studies, and a limited number of experimental models amenable to more traditional in vitro and in vivo studies of structural, mechanistic and regulatory properties of diverse MGEs. Experimental and computational scientists came together to bridge this gap at a recent conference, 'Mobile Genetic Elements: in silico, in vitro, in vivo', held at the Marine Biological Laboratory (MBL) in Woods Hole, MA, USA.
authors.affiliation: Josephine Bay Paul Center for Comparative Molecular Biology and Evolution, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA, 02543, USA.
authors.forename: Irina R
authors.initials: IR
authors.lastname: Arkhipova
authors.affiliation: Department of Biochemistry and Molecular Biology, The University of Chicago, 929 E. 57th Street, Chicago, IL, 60637, USA.
authors.forename: Phoebe A
authors.initials: PA
authors.lastname: Rice
mesh_terms: D019295:Computational Biology; D003226:Congresses as Topic; D004251:DNA Transposable Elements; D030541:Databases, Genetic; D004720:Endonucleases; D005786:Gene Expression Regulation; D023281:Genomics; D047668:Inteins; D007438:Introns; D019895:Transposases
chemical_list: D004251:DNA Transposable Elements; D019895:Transposases; D004720:Endonucleases
keywords: bioinformatics; genomics; retrotransposons; transposable elements; transposition
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