title: A novel non-enzymatic glucose sensor based on Pt3Ru1 alloy nanoparticles with high density of surface defects.
abstract: A novel non-enzymatic glucose sensor based on a glassy carbon electrode modified with Pt3Ru1 alloy nanoparticles (Pt3Ru1/GCE) was fabricated. Pt3Ru1 alloy nanoparticles were prepared by a reverse microemulsion method at room temperature. The X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDS) demonstrate that Pt3Ru1 nanoparticles are disordered alloy with face central cubic (fcc) structure and the atom ratio of Pt and Ru is 3:1. The high-resolution transmission electron microscopy (HRTEM) images show that Pt3Ru1 alloy nanoparticles were aggregated with a high density of surface defects. Furthermore, the sensor properties of Pt3Ru1/GCE were investigated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and chronoamperometry (CA) in 0.01 M PBS (pH 7.4). The results indicate that the proposed sensor exhibits a wide linear range of 5 × 10(-7)M to 10(-2)M (R(2)=0.9988) with a low detection limit of 0.3 μM for glucose. Moreover, the sensor demonstrates good sensitivity, stability, reproducibility, and better anti-interference performance toward ascorbic acid (AA), uric acid (UA), and fructose (Fru).
authors.affiliation: Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China.
authors.forename: Jiangwei
authors.initials: J
authors.lastname: Yang
authors.affiliation: Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China. Electronic address: lxyi@tjcu.edu.cn.
authors.forename: Xinyi
authors.initials: X
authors.lastname: Liang
authors.affiliation: College of Materials Science and Engineering, Tianjin University, Tianjin 300072, PR China.
authors.forename: Lan
authors.initials: L
authors.lastname: Cui
authors.affiliation: Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Liu
authors.affiliation: Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China.
authors.forename: Junbo
authors.initials: J
authors.lastname: Xie
authors.affiliation: Tianjin Key Laboratory of Food and Biotechnology, Department of Applied Chemistry, College of Science, Tianjin University of Commerce, Tianjin 300134, PR China.
authors.forename: Weixing
authors.initials: W
authors.lastname: Liu
mesh_terms: D001205:Ascorbic Acid / Q000737:chemistry; D015374:Biosensing Techniques; D002244:Carbon / Q000737:chemistry; D058266:Dielectric Spectroscopy; D055664:Electrochemical Techniques; D005632:Fructose / Q000737:chemistry; D005947:Glucose / Q000737:chemistry / Q000302:isolation & purification*; D057230:Limit of Detection; D053758:Nanoparticles / Q000737:chemistry*; D010984:Platinum / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry; D014527:Uric Acid / Q000737:chemistry
chemical_list: D014527:Uric Acid; D005632:Fructose; D010984:Platinum; D002244:Carbon; D012428:Ruthenium; D005947:Glucose; D001205:Ascorbic Acid
keywords: Glucose; Non-enzymatic sensor; Pt(3)Ru(1) alloy nanoparticles; Surface defect