title: Densitometric evaluation might prevent failure of knee artroplasty for aseptic loosening. An 8-year observational controlled study.
abstract: OBJECTIVE
  To study the correlation between quantitative ultrasound (QUS) expressed as stiffness index (SI) and the risk of aseptic loosening of knee arthroplasty.
  
  
  METHODS
  An observational retrospective controlled study was performed on 85 female patients (mean age: 73.3 years) divided into 2 groups from January 2007 to March 2015 and carried out at the Orthopedic Rehabilitation Unit, Casa di Cura Eremo, Arco, Trento, Italy. Group A included 42 patients who had undergone a revision of knee prosthesis for aseptic-loosening, and group B included 43 age-matched patients who underwent primary replacement of the knee without following aseptic loosening. Patients in both groups were evaluated for SI with Achilles - QUS system at the same side of the surgery.
  
  
  RESULTS
  In group A, 20/42 patients (47.6%) had an SI T-score below -2.5. In group B, 14/43 (32.5%) patients had a SI T-score below -2.5. The difference between the 2 groups was statistically significant (p=0.015).
  
  
  CONCLUSIONS
  Stiffness index appears to be an important predictor of aseptic loosening of the knee prosthesis. Therefore, densitometric evaluation, including SI, may be recommended before surgical knee replacement.
authors.affiliation: Rheumatology and Rehabilitation Unit, Salvatore Maugeri Foundation IRCCS, Castel Goffredo, Mantua, Italy. E-mail. gianantonio.saviola@fsm.it.
authors.forename: Gianantonio
authors.initials: G
authors.lastname: Saviola
authors.forename: Irene
authors.initials: I
authors.lastname: Zaghini
authors.forename: Lul
authors.initials: L
authors.lastname: Abdi-Ali
authors.forename: Gregorio
authors.initials: G
authors.lastname: Ferlini
authors.forename: Silvano
authors.initials: S
authors.lastname: Sacco
authors.forename: Maurizio
authors.initials: M
authors.lastname: Rossini
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D016022:Case-Control Studies; D003720:Densitometry / Q000379:methods*; D005260:Female; D006801:Humans; D007558:Italy / Q000453:epidemiology; D007719:Knee Joint / Q000000981:diagnostic imaging; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000453:epidemiology*; D011475:Prosthesis Failure; D012086:Reoperation; D012189:Retrospective Studies; D018570:Risk Assessment; D014463:Ultrasonography
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