title: Microbiology: Social Suicide for a Good Cause.
abstract: Extracellular DNA is an important component of the biofilm matrix. Now, Pseudomonas aeruginosa is shown to control autolysis through the production of HQNO, a quorum-sensing-regulated respiratory poison. Thus, HQNO-driven autolysis links programmed cell death with quorum sensing and biofilm formation.
authors.affiliation: Pulmonary and Critical Care Medicine and, University of Pittsburgh, Pittsburgh, PA, USA.
authors.forename: Anna C
authors.initials: AC
authors.lastname: Zemke
authors.affiliation: Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: jbomb@pitt.edu.
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Bomberger
mesh_terms: D006801:Humans; D018441:Biofilms; D011550:Pseudomonas aeruginosa; D053038:Quorum Sensing