title: Retrospective study of 289 odontogenic tumors in a Brazilian population.
abstract: BACKGROUND
  Odontogenic tumors (OTs) are considered important among oral lesions because of their clinicopathological heterogeneity, and variable biological behavior. This paper aims to determine the frequency and distribution of OTs, over a period of 10 years, at a public university in Northeastern Brazil and compare this data with previous reports.
  
  
  METHODS
  We reviewed all cases of OTs from oral pathology laboratory of University of Pernambuco (UPE), from 2004 to 2014. Diagnoses were re-evaluated and the tumors were classified according to the latest (2005) World Health Organization Classification of Tumors. In addition, we searched in the English-language literature retrospective studies on OTs that used the same classification.
  
  
  RESULTS
  Within the total of 6028 oral biopsies, 289 (4.79%) were OTs. Of these, 287 (99.3%) were benign and 2 (0.7%) were malignant. The overall incidence was 31.1/million. Mandible-maxilla ratio was 2.5:1 and mean age 35 years. Keratocystic odontogenic tumor (KCOT) (34.6%) was the most frequent lesion, followed by ameloblastoma (AMB) (32.9%) and odontoma (ODO) (11.4%).
  
  
  CONCLUSIONS
  OTs are uncommon neoplasms with geographic variation. Our clinicopathological features are according to literature. In the present study, KCOT was the most frequent one, showing that the new classification of OTs altered the distribution of these lesions and possibly made KCOT the most common OT observed in diagnostic services worldwide.
authors.affiliation: Department of Dentistry, Postgraduate Program in Oral Pathology, Federal University of Rio Grande do Norte (UFRN), Av. Salgado Filho, 1787, Lagoa Nova - Natal/RN CEP: 59056-000, leorikp@gmail.com.
authors.forename: L-P
authors.initials: LP
authors.lastname: da Silva
authors.forename: M-S
authors.initials: MS
authors.lastname: Serpa
authors.forename: J-R
authors.initials: JR
authors.lastname: Tenório
authors.forename: G-J-F
authors.initials: GJ
authors.lastname: do Nascimento
authors.forename: E-S
authors.initials: ES
authors.lastname: de Souza-Andrade
authors.forename: A-P
authors.initials: AP
authors.lastname: Veras-Sobral
mesh_terms: D000328:Adult; D000564:Ameloblastoma / Q000175:diagnosis / Q000473:pathology*; D001938:Brazil; D005260:Female; D006801:Humans; D008297:Male; D009808:Odontogenic Tumors / Q000175:diagnosis / Q000473:pathology*; D009810:Odontoma / Q000175:diagnosis / Q000473:pathology*; D012189:Retrospective Studies
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