title: Molecular Characteristics of Influenza Virus Type B Lineages Circulating in Poland.
abstract: From the time of the Hong Kong pandemic of 1968-1969, vaccines against influenza are trivalent, containing two subtypes of influenza type A: A/H1N1/ and A/H3N2/, and influenza type B. In 1980, circulation of the new Yamagata and Victoria lineages of influenza B virus was noted. Since both lineages have continued to circulate, the second lineage of influenza B was included into the trivalent vaccine as of the 2013/2014 epidemic season. In Poland, co-circulation of influenza type A and B has been registered over many seasons, although type A has predominated. According to the ACIP recommendations, quadrivalent vaccines against influenza are administered in some continents due to circulation of the B-Yamagata and B-Victoria lineages. Currently, only trivalent vaccines against influenza are available in Poland. The aim of the present research was to determine which of the two influenza type B lineages, or possibly both, would be isolated in Poland. The study was conducted with the use of RT-PCR. Generally, in the 2014/2015 epidemic season in Poland, circulation of type B virus was confirmed in 34 % of influenza cases. A total of 89 specimens of influenza B were tested, including co-infections of influenza B with influenza A subtypes: A/H1N1/pdm09 and A/H3N2/. The findings were that only lineage B-Yamagata circulates in the Polish population. Therefore, vaccines available on the Polish market do not require the introduction of a fourth component.
authors.affiliation: Department of Influenza Research, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland. karolina.bed88@gmail.com.
authors.forename: K
authors.initials: K
authors.lastname: Bednarska
authors.affiliation: Department of Influenza Research, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.
authors.forename: E
authors.initials: E
authors.lastname: Hallmann-Szelińska
authors.affiliation: Department of Influenza Research, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Kondratiuk
authors.affiliation: Centre of Monitoring and Analyses of Population Health Status, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.
authors.forename: D
authors.initials: D
authors.lastname: Rabczenko
authors.affiliation: Department of Influenza Research, National Influenza Center, National Institute of Public Health - National Institute of Hygiene, 24 Chocimska St., 00-791, Warsaw, Poland.
authors.forename: L B
authors.initials: LB
authors.lastname: Brydak
mesh_terms: D000818:Animals; D004285:Dogs; D058872:Epidemics; D005838:Genotype; D006385:Hemagglutination Inhibition Tests; D006801:Humans; D009981:Influenza B virus / Q000235:genetics*; D007251:Influenza, Human / Q000453:epidemiology / Q000821:virology*; D061985:Madin Darby Canine Kidney Cells; D011044:Poland / Q000453:epidemiology; D012367:RNA, Viral / Q000032:analysis*; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D012367:RNA, Viral
keywords: Epidemic season; Influenza vaccine; Influenza virus; Lineages; Quadrivalent vaccine; Trivalent vaccine