title: HPV Involvement in Head and Neck Cancers: Comprehensive Assessment of Biomarkers in 3680 Patients.
abstract: BACKGROUND
  We conducted a large international study to estimate fractions of head and neck cancers (HNCs) attributable to human papillomavirus (HPV-AFs) using six HPV-related biomarkers of viral detection, transcription, and cellular transformation.
  
  
  METHODS
  Formalin-fixed, paraffin-embedded cancer tissues of the oral cavity (OC), pharynx, and larynx were collected from pathology archives in 29 countries. All samples were subject to histopathological evaluation, DNA quality control, and HPV-DNA detection. Samples containing HPV-DNA were further subject to HPV E6*I mRNA detection and to p16(INK4a), pRb, p53, and Cyclin D1 immunohistochemistry. Final estimates of HPV-AFs were based on HPV-DNA, HPV E6*I mRNA, and/or p16(INK4a) results.
  
  
  RESULTS
  A total of 3680 samples yielded valid results: 1374 pharyngeal, 1264 OC, and 1042 laryngeal cancers. HPV-AF estimates based on positivity for HPV-DNA, and for either HPV E6*I mRNA or p16(INK4a), were 22.4%, 4.4%, and 3.5% for cancers of the oropharynx, OC, and larynx, respectively, and 18.5%, 3.0%, and 1.5% when requiring simultaneous positivity for all three markers. HPV16 was largely the most common type. Estimates of HPV-AF in the oropharynx were highest in South America, Central and Eastern Europe, and Northern Europe, and lowest in Southern Europe. Women showed higher HPV-AFs than men for cancers of the oropharynx in Europe and for the larynx in Central-South America.
  
  
  CONCLUSIONS
  HPV contribution to HNCs is substantial but highly heterogeneous by cancer site, region, and sex. This study, the largest exploring HPV attribution in HNCs, confirms the important role of HPVs in oropharyngeal cancer and drastically downplays the previously reported involvement of HPVs in the other HNCs.
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Xavier
authors.initials: X
authors.lastname: Castellsagué
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Laia
authors.initials: L
authors.lastname: Alemany
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Miquel
authors.initials: M
authors.lastname: Quer
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Gordana
authors.initials: G
authors.lastname: Halec
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Beatriz
authors.initials: B
authors.lastname: Quirós
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Sara
authors.initials: S
authors.lastname: Tous
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Omar
authors.initials: O
authors.lastname: Clavero
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Llúcia
authors.initials: L
authors.lastname: Alòs
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Thorsten
authors.initials: T
authors.lastname: Biegner
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Tomasz
authors.initials: T
authors.lastname: Szafarowski
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Maria
authors.initials: M
authors.lastname: Alejo
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Dana
authors.initials: D
authors.lastname: Holzinger
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Enrique
authors.initials: E
authors.lastname: Cadena
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Edith
authors.initials: E
authors.lastname: Claros
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Gillian
authors.initials: G
authors.lastname: Hall
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Jan
authors.initials: J
authors.lastname: Laco
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Mario
authors.initials: M
authors.lastname: Poljak
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Maria
authors.initials: M
authors.lastname: Benevolo
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Elena
authors.initials: E
authors.lastname: Kasamatsu
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Hisham
authors.initials: H
authors.lastname: Mehanna
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Cathy
authors.initials: C
authors.lastname: Ndiaye
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Núria
authors.initials: N
authors.lastname: Guimerà
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Belen
authors.initials: B
authors.lastname: Lloveras
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Xavier
authors.initials: X
authors.lastname: León
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Juan C
authors.initials: JC
authors.lastname: Ruiz-Cabezas
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Isabel
authors.initials: I
authors.lastname: Alvarado-Cabrero
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Chang-Suk
authors.initials: CS
authors.lastname: Kang
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Jin-Kyoung
authors.initials: JK
authors.lastname: Oh
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Marcial
authors.initials: M
authors.lastname: Garcia-Rojo
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Ermina
authors.initials: E
authors.lastname: Iljazovic
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Oluseyi F
authors.initials: OF
authors.lastname: Ajayi
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Flora
authors.initials: F
authors.lastname: Duarte
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Ashrafun
authors.initials: A
authors.lastname: Nessa
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Leopoldo
authors.initials: L
authors.lastname: Tinoco
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Marco A
authors.initials: MA
authors.lastname: Duran-Padilla
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Edyta C
authors.initials: EC
authors.lastname: Pirog
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Halina
authors.initials: H
authors.lastname: Viarheichyk
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Hesler
authors.initials: H
authors.lastname: Morales
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Valérie
authors.initials: V
authors.lastname: Costes
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Ana
authors.initials: A
authors.lastname: Félix
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Maria Julieta V
authors.initials: MJ
authors.lastname: Germar
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Marisa
authors.initials: M
authors.lastname: Mena
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Arzu
authors.initials: A
authors.lastname: Ruacan
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Asha
authors.initials: A
authors.lastname: Jain
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Ravi
authors.initials: R
authors.lastname: Mehrotra
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Marc T
authors.initials: MT
authors.lastname: Goodman
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Luis Estuardo
authors.initials: LE
authors.lastname: Lombardi
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Annabelle
authors.initials: A
authors.lastname: Ferrera
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Sani
authors.initials: S
authors.lastname: Malami
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Estela I
authors.initials: EI
authors.lastname: Albanesi
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Pablo
authors.initials: P
authors.lastname: Dabed
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Carla
authors.initials: C
authors.lastname: Molina
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Rubén
authors.initials: R
authors.lastname: López-Revilla
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Václav
authors.initials: V
authors.lastname: Mandys
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Manuel E
authors.initials: ME
authors.lastname: González
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Julio
authors.initials: J
authors.lastname: Velasco
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Ignacio G
authors.initials: IG
authors.lastname: Bravo
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Wim
authors.initials: W
authors.lastname: Quint
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Michael
authors.initials: M
authors.lastname: Pawlita
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Nubia
authors.initials: N
authors.lastname: Muñoz
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: Silvia
authors.initials: S
authors.lastname: de Sanjosé
authors.affiliation: Cancer Epidemiology Research Program, Catalan Institute of Oncology (ICO), IDIBELL, L'Hospitalet de Llobregat, Catalonia, Spain (XC, LAle, BQ, ST, OC, MM, IGB, SdS, FXB); CIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain (XC, LAle, SdS); Hospital Sant Pau, Barcelona, Spain (MQ, XL); German Cancer Research Center (DKFZ), Heidelberg, Germany (GHale, DH, MPa); Hospital Clínic, University of Barcelona, Spain (LAlò); Department of Pathology, University Hospital Tuebingen, Tuebingen, Germany (TB); Department of Otorhinolaryngology, Faculty of Medicine and Dentistry, Warsaw Medical University, Czerniakowski Hospital, Warsaw, Poland (TS); Hospital General de l'Hospitalet, L'Hospitalet de Llobregat, Barcelona, Spain (MA); Instituto Nacional de Cancerología, Bogotá, Colombia (ECa, NM); Universidad Nacional de Colombia, Bogotá, Colombia (ECa); Insituto Oncológico del Oriente Boliviano (IOOB), Laboratorio Privado de Patología Oncos, Santa Cruz, Bolivia (ECl); Manchester Royal Infirmary, Manchester, UK (GHall); The Fingerland Department of Pathology, Charles University Faculty of Medicine and University Hospital, Hradec Kralove, Czech Republic (JL); University of Ljubljana, Faculty of Medicine, Institute of Microbiology and Immunology, Ljubljana, Slovenia (MPo); Regina Elena National Cancer Institute, Rome, Italy (MB); Instituto de Investigaciones en Ciencias de la Salud, Universidad Nacional de Asunción, Asunción, Paraguay (EK); Institute of Head and Neck Studies and Education, University of Birmingham, Birmingham, UK (HMe); Department of Social and Preventive Medicine, Université de Montréal, Montreal, Canada (CN); DDL Diagnostic Laboratory, Rijswijk, the Netherlands (NG, WQ); Pathology Department, Hospital del Mar IMIM, Universitat Pompeu Fabra, Barcelona, Spain (BL); Laboratorio Clínico y Molecular, Hospital SOLCA, Guayaquil, Ecuador (JCRC); Hospital de Oncología Centro Médico Nacional Siglo XXI, IMSS Mexico, D.F., Mexico (IAC); Yeouido St. Mary's
authors.forename: F
authors.initials: F
authors.lastname: Xavier Bosch
mesh_terms: D000328:Adult; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis*; D002294:Carcinoma, Squamous Cell / Q000737:chemistry* / Q000821:virology*; D003430:Cross-Sectional Studies; D019938:Cyclin D1 / Q000032:analysis; D019941:Cyclin-Dependent Kinase Inhibitor p16 / Q000032:analysis; D004279:DNA, Viral / Q000302:isolation & purification; D005260:Female; D005838:Genotype; D006258:Head and Neck Neoplasms / Q000821:virology; D052162:Human papillomavirus 16 / Q000302:isolation & purification; D006801:Humans; D007150:Immunohistochemistry; D007391:International Cooperation; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000737:chemistry* / Q000821:virology*; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000150:complications* / Q000821:virology; D011237:Predictive Value of Tests; D055273:Salivary Proline-Rich Proteins / Q000032:analysis; D016159:Tumor Suppressor Protein p53 / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; C530104:CCND1 protein, human; D019941:Cyclin-Dependent Kinase Inhibitor p16; D004279:DNA, Viral; D055273:Salivary Proline-Rich Proteins; D016159:Tumor Suppressor Protein p53; D019938:Cyclin D1