title: ABO blood group mismatched hematopoietic stem cell transplantation.
abstract: Apart from solid organ transplantations, use of ABO-blood group mismatched (ABO-mismatched) donors is acceptable in hematopoietic stem cell transplantation (HSCT) patients. About 20-40% of allogeneic HSCT recipients will receive grafts from ABO-mismatched donors. ABO incompatible HSCT procedures are associated with immediate and late consequences, including but not restricted to acute or delayed hemolytic reactions, delayed red blood cell recovery, pure red cell aplasia and graft-versus-host disease. This review summarizes the current knowledge about consequences of ABO-mismatched HSCT in terms of associated complications and will evaluate its impact on important outcome parameters of HSCT.
authors.affiliation: Pediatric Hematology and Oncology, Ankara Keçiören Training and Research Hospital, Ankara, Turkey. Electronic address: sibelakp@yahoo.com.
authors.forename: Sibel Akpınar
authors.initials: SA
authors.lastname: Tekgündüz
authors.affiliation: Pediatric Hematology and Bone Marrow Transplantation Units, Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital, Ankara, Turkey; Apheresis and Blood Bank Units, Ankara Child Health and Diseases Hematology Oncology Training and Research Hospital, Ankara, Turkey.
authors.forename: Namık
authors.initials: N
authors.lastname: Özbek
mesh_terms: D000017:ABO Blood-Group System / Q000378:metabolism*; D001787:Blood Group Incompatibility / Q000150:complications*; D001803:Blood Transfusion; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans
chemical_list: D000017:ABO Blood-Group System
keywords: ABO mismatch; Allogeneic hematopoietic stem cell transplantation; Engrafment; Transfusion; Transplantation complications