title: Benign Diseases of the Bladder.
abstract: Benign diseases of the bladder often present diagnostic challenges to practicing pathologists due to their diverse nature and ability to mimic a variety of epithelial or mesenchymal neoplasms. Categories of benign bladder disease include infectious cystitis, noninfectious cystitis, reactive proliferative processes, and benign processes that secondarily involve the bladder. An understanding of the key clinical and morphologic features of these lesions and the useful ancillary techniques specific for these entities is critical to the correct diagnosis of these lesions. This article reviews the key features of these benign bladder diseases and highlights methods to distinguish these lesions from other benign and malignant processes involving the bladder.
authors.affiliation: Department of Anatomic Pathology, The Cleveland Clinic, 9500 Euclid Avenue, Desk L25, Cleveland, OH 44195, USA.
authors.forename: Joshua F
authors.initials: JF
authors.lastname: Coleman
authors.affiliation: Department of Anatomic Pathology, Glickman Urological and Kidney Institute, Taussig Cancer Institute, The Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, The Cleveland Clinic, 9500 Euclid Avenue, Desk L25, Cleveland, OH 44195, USA. Electronic address: hanseld@ccf.org.
authors.forename: Donna E
authors.initials: DE
authors.lastname: Hansel
keywords: Amyloidosis; Benign bladder diseases; Bladder; Bladder pathology; Cystitis cystica; Cystitis glandularis; Ectopic prostatic tissue; Endometriosis; Eosinophilic cystitis; Fungal cystitis; Granulomatous cystitis; Histology; Infection; Inflammation; Interstitial cystitis; Malakoplakia; Mimickers; Nephrogenic adenoma; Pathology; Polyomavirus infection; Polypoid cystitis; Reactive response; Therapy-induced cystitis; Von Brunn's nests