title: Radiation Toxicity to the Cardiovascular System.
abstract: Radiation therapy is an important component of cancer treatment, and today, it is applied to approximately 50% of malignancies, including valvular, myocardial, pericardial, coronary or peripheral vascular disease, and arrhythmias. An increased clinical suspicion and knowledge of those mechanisms is important to initiate appropriate screening for the optimal diagnosis and treatment. As the number of cancer survivors has been steadily increasing over the last decades, cardio-oncology, an evolving subspecialty of cardiology, will soon play a pivotal role in raising awareness of the increased cardiovascular risk and formulate strategies to optimally manage patients in this unique population.
authors.affiliation: CMH Heart and Vascular Institute, 1500 N Oakland Rd, Bolivar, MO, 65613, USA. c.marmagiolis@gmail.com.|University of Missouri, Columbia, MO, USA. c.marmagiolis@gmail.com.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Marmagkiolis
authors.affiliation: Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. wfinch@mednet.ucla.edu.
authors.forename: William
authors.initials: W
authors.lastname: Finch
authors.affiliation: Wayne State University, 42 W Warren Ave, Detroit, MI, 48202, USA. despina1023@gmail.com.
authors.forename: Despina
authors.initials: D
authors.lastname: Tsitlakidou
authors.affiliation: Kansas City University of Medicine and Biosciences, 1750 Independence Ave, Kansas City, MO, 64106, USA. tjosephs@kcumb.edu.
authors.forename: Tyler
authors.initials: T
authors.lastname: Josephs
authors.affiliation: MD Anderson Cancer Center, University of Texas, Houston, TX, USA. ciliescu@mdanderson.org.
authors.forename: Cezar
authors.initials: C
authors.lastname: Iliescu
authors.affiliation: CMH Heart and Vascular Institute, 1500 N Oakland Rd, Bolivar, MO, 65613, USA. bestjo@citizensmemorial.com.
authors.forename: John F
authors.initials: JF
authors.lastname: Best
authors.affiliation: Division of Cardiology, Department of Medicine, University of California at Los Angeles, Los Angeles, CA, USA. datsunian@gmail.com.
authors.forename: Eric H
authors.initials: EH
authors.lastname: Yang
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy; D002318:Cardiovascular Diseases / Q000209:etiology*; D002319:Cardiovascular System / Q000528:radiation effects*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy; D006801:Humans; D009369:Neoplasms / Q000401:mortality / Q000532:radiotherapy*; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects*; D017741:Survivors
keywords: Radiation-induced cardiovascular toxicity; Valvular pericardial heart disease
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