title: Low vascularity predicts favourable outcomes in leiomyoma patients treated with uterine artery embolization.
abstract: OBJECTIVE
  To investigate the clinical factors predicting outcomes of leiomyoma treated with uterine artery embolization (UAE).
  
  
  METHODS
  A total of 183 uterine leiomyoma patients undergoing UAE were retrospectively analyzed. Patient age, characteristics of vascular supply in magnetic resonance imaging (MRI)/digital subtraction angiography (DSA), number, size and location of leiomyoma were recorded. Leiomyoma regrowth, new leiomyoma appearance and recurrence of any previously reported symptoms were carefully monitored over a mean follow-up of 30 months (median 32 months, range 12-80). Potential recurrence risk factors were analyzed by univariate and multivariate cox regression analysis.
  
  
  RESULTS
  Twenty-three recurrences were recorded. The difference in the vascularity classification systems between MRI and DSA was not statistically significant (P = 0.059). High vascularity in MRI, high vascularity in DSA and multiple leiomyoma showed a significant risk of recurrence using univariate and multivariate analysis (P = 0.004, P < 0.001 and P = 0.023, respectively). The other factors were not significantly associated with leiomyoma recurrence (P > 0.05).
  
  
  CONCLUSIONS
  Low vascularity and solitary leiomyoma indicated favourable outcomes in patients treated with UAE.
  
  
  CONCLUSIONS
  • Low vascularity and solitary mass predicted favourable outcomes in UAE-treated patients. • MRI might provide information on vascularity in leiomyoma before UAE. • Variations in vascular supply, age, size, location were not associated with recurrence.
authors.affiliation: Department of Gynecology, The Second Affiliated Hospital, Zhejiang University, Hangzhou, 310009, People's Republic of China.|Department of Obstetrics and Gynecology, Nan fang Hospital of the Southern Medical University, Guangzhou, 510515, People's Republic of China.
authors.forename: Yixin
authors.initials: Y
authors.lastname: Tang
authors.affiliation: Department of Obstetrics and Gynecology, Nan fang Hospital of the Southern Medical University, Guangzhou, 510515, People's Republic of China.
authors.forename: Chunlin
authors.initials: C
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, Nan fang Hospital of the Southern Medical University, Guangzhou, 510515, People's Republic of China.
authors.forename: Hui
authors.initials: H
authors.lastname: Duan
authors.affiliation: Department of Obstetrics and Gynecology, Guangzhou First Municipal People's Hospital, No. 1, Pan Fu Road, Guangzhou, 510180, People's Republic of China.
authors.forename: Ben
authors.initials: B
authors.lastname: Ma
authors.affiliation: Department of Obstetrics and Gynecology, Nan fang Hospital of the Southern Medical University, Guangzhou, 510515, People's Republic of China. lpivy1@126.com.
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
mesh_terms: D000328:Adult; D015901:Angiography, Digital Subtraction / Q000379:methods; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*; D018810:Magnetic Resonance Angiography / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome; D055357:Uterine Artery Embolization / Q000379:methods*; D014594:Uterine Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology / Q000628:therapy*
keywords: Embolization; Leiomyoma; Prognosis; Recurrence; Vascularity
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