title: Total hip replacement in osteoarthritis: the role of bone metabolism and its complications.
abstract: Osteoarthritis is one of the most common joint disorder. For treatment of hip symptomatic osteoarthritis, when conservative medical therapy has failed, total hip arthroplasty (THA) is a successful orthopaedic procedures that reduces pain and improves function and quality of life. Incidence of osteoarthritis is constantly increasing with raising life expectancy. This aging process also has led to an increasing number of patients with osteoporosis who need hip replacement for osteoarthritis. Osteoporosis have 3 major potential complications in total hip arthroplasty: perioperative fracture, an increased risk of periprosthetic fracture, and late aseptic loosening. The purpose of the present study was to examine the effects of osteoporosis on total hip replacement procedure outcome and highlight the importance of adequate study of calcium-phosphorus metabolism in patient candidate for hip surgery, and the need to start a suitable therapy to recover the bone mass before surgery. Bone quality of the hip joint has become an important risk factor limiting the durability of THA.
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Vanna
authors.initials: V
authors.lastname: Bottai
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Dell'Osso
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Celli
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Bugelli
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Niki
authors.initials: N
authors.lastname: Cazzella
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Cei
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Giulio
authors.initials: G
authors.lastname: Guido
authors.affiliation: II Orthopaedic and Traumatologic Clinic, University of Pisa, Pisa, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Giannotti
keywords: bone metabolism; perioperative and periprosthetic fracture; total hip replacement
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