title: Sulfonamide-directed gold-catalyzed [2+2+2]-cycloadditions of nitriles with two discrete ynamides to construct 2,4-diaminopyridine cores.
abstract: Gold-catalyzed [2+2+2]-cycloadditions of two discrete ynamides and one nitrile afford 2,4-diaminopyridine derivatives that are not readily prepared from typical low-valent-metal catalysts. Our mechanistic analysis reveals that the reaction chemoselectivity is controlled by the types of sulfonamides of ynamides.
authors.affiliation: Department of Chemistry, National Tsing-Hua University, 101, Sec. 2, Kuang-Fu Rd, Hsinchu, 30043, Taiwan, Republic of China. rsliu@mx.nthu.edu.tw.
authors.forename: Yu-Ling
authors.initials: YL
authors.lastname: Chen
authors.affiliation: Department of Chemistry, National Tsing-Hua University, 101, Sec. 2, Kuang-Fu Rd, Hsinchu, 30043, Taiwan, Republic of China. rsliu@mx.nthu.edu.tw.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Sharma
authors.affiliation: Department of Chemistry, National Tsing-Hua University, 101, Sec. 2, Kuang-Fu Rd, Hsinchu, 30043, Taiwan, Republic of China. rsliu@mx.nthu.edu.tw.
authors.forename: Rai-Shung
authors.initials: RS
authors.lastname: Liu