title: The MOGE(S) classification : A TNM-like classification for cardiomyopathies.
abstract: Cardiomyopathy is a disease of the heart muscle resulting from genetic defects, cardiac myocyte injury, or infiltration of the myocardium. Cardiomyopathies are traditionally defined as dilated, restrictive, and hypertrophic cardiomyopathy. Today, the genetic basis of most diseases has been clearly defined and has influenced the approach to familial diseases such as cardiomyopathies. Traditional definitions of cardiomyopathies, such as those by the American Heart Association and the European Society of Cardiology, do not consider the genetic basis of cardiomyopathies. In 2013, the World Heart Federation added the genetic basis of cardiomyopathies and proposed a descriptive genotype-phenotype nosology system termed "MOGE(S)." The MOGE(S) system resembles the TNM classification system for malignancy, and therefore it can be useful for the diagnosis, management, and treatment of cardiomyopathies in a similar manner to cancer management.
authors.affiliation: Cardiology, Atatürk Pulmonary Disease and Thorax Surgery Research Hospital, Ankara, Turkey. ekremsahan@hotmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Şahan
authors.affiliation: Cardiology, Turkiye Yuksek Ihtısas Training and Research Hospital, Ankara, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Şahan
authors.affiliation: Cardiology, Atatürk Pulmonary Disease and Thorax Surgery Research Hospital, Ankara, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Karamanlıoğlu
authors.affiliation: Cardiology, Ercis State Hospital, Van, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Gul
authors.affiliation: Cardiology, Turkiye Yuksek Ihtısas Training and Research Hospital, Ankara, Turkey.
authors.forename: O
authors.initials: O
authors.lastname: Tufekcioğlu
mesh_terms: D002309:Cardiology / Q000592:standards*; D009202:Cardiomyopathies / Q000145:classification* / Q000175:diagnosis / Q000235:genetics*; D005819:Genetic Markers / Q000235:genetics*; D006801:Humans; D038801:International Classification of Diseases
chemical_list: D005819:Genetic Markers
keywords: Cardiomyopathy; Classification; Genetics; MOGES; Myocardium
references.citation: Circulation. 2006 Apr 11;113(14):1807-16
references.pmid: 16567565
references.citation: Neuromuscul Disord. 2008 Jan;18(1):34-44
references.pmid: 17897828
references.citation: Acta Neuropathol. 2009 Mar;117(3):293-307
references.pmid: 19151983
references.citation: Europace. 2000 Jan;2(1):4-14
references.pmid: 11225594
references.citation: Biochem J. 2011 May 15;436(1):113-21
references.pmid: 21361873
references.citation: Eur Heart J. 2008 Jan;29(2):270-6
references.pmid: 17916581
references.citation: J Am Coll Cardiol. 2011 Aug 23;58(9):925-34
references.pmid: 21851881
references.citation: J Am Coll Cardiol. 2008 Oct 7;52(15):1250-60
references.pmid: 18926329
references.citation: Br Heart J. 1972 Jun;34(6):545-52
references.pmid: 4402697
references.citation: Eur J Pediatr. 2014 Feb;173(2):239-42
references.pmid: 23989969
references.citation: Acta Neuropathol. 2013 Jan;125(1):47-75
references.pmid: 23143191
references.citation: Herz. 2009 Feb;34(1):55-62
references.pmid: 19214409
references.citation: J Am Coll Cardiol. 2012 Jan 31;59(5):493-500
references.pmid: 22281253
references.citation: Glob Heart. 2013 Dec;8(4):355-82
references.pmid: 25690638
references.citation: Curr Opin Rheumatol. 1996 Nov;8(6):528-38
references.pmid: 9018456
references.citation: Semin Pediatr Neurol. 2002 Jun;9(2):100-7
references.pmid: 12138994
references.citation: Br Heart J. 1980 Dec;44(6):672-3
references.pmid: 7459150
references.citation: Circulation. 2013 Jan 1;127(1):126-40
references.pmid: 23283857
references.citation: Neuromuscul Disord. 2013 Jan;23(1):4-14
references.pmid: 23116935
references.citation: Circulation. 1956 Feb;13(2):217-23
references.pmid: 13356381
references.citation: Lancet. 1957 Dec 14;273(7007):1179-84
references.pmid: 13492602
references.citation: Orphanet J Rare Dis. 2013 Feb 14;8:26
references.pmid: 23406536
references.citation: J Electrocardiol. 2005 Oct;38(4 Suppl):81-7
references.pmid: 16226080