title: A nucleotide insertion in Exon 2 is responsible for a new HLA-DRB1 null allele, HLA-DRB1*14:166N.
abstract: DRB1*14 is identical to DRB1*14:54:01 except for a single nucleotide insertion of A in position 175 in Exon 2.
authors.affiliation: IME Foundation at Polyclinic of Tor Vergata, Laboratory of Immunogenetics and Transplant Biology, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Testi
authors.affiliation: IME Foundation at Polyclinic of Tor Vergata, Laboratory of Immunogenetics and Transplant Biology, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Troiano
authors.affiliation: IME Foundation at Polyclinic of Tor Vergata, Laboratory of Immunogenetics and Transplant Biology, Rome, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Paladini
authors.affiliation: IME Foundation at Polyclinic of Tor Vergata, Laboratory of Immunogenetics and Transplant Biology, Rome, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Di Luzio
authors.affiliation: IME Foundation at Polyclinic of Tor Vergata, Laboratory of Immunogenetics and Transplant Biology, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Andreani
mesh_terms: D000483:Alleles; D001483:Base Sequence; D018389:Codon, Nonsense; D005091:Exons; D016368:Frameshift Mutation; D015870:Gene Expression; D056426:Genetic Loci; D059811:HLA-DRB1 Chains / Q000235:genetics* / Q000276:immunology; D018380:Hematopoietic Stem Cell Transplantation; D006412:Hematopoietic Stem Cells / Q000166:cytology / Q000276:immunology*; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D016415:Sequence Alignment; D017422:Sequence Analysis, DNA; D061349:Unrelated Donors
chemical_list: D018389:Codon, Nonsense; D059811:HLA-DRB1 Chains
keywords: HLA‐DRB1*14:166N; null allele; sequence‐based typing