title: Magnetic resonance parkinsonism index in progressive supranuclear palsy and vascular parkinsonism.
abstract: To investigate accuracy of the magnetic resonance parkinsonism index (MRPI) in differentiating progressive supranuclear palsy (PSP) from vascular parkinsonism (VP). We retrospectively analyzed radiological data of 12 PSP patients and 17 VP patients group-matched by age and sex who performed a standardized brain magnetic resonance imaging (MRI). Analysis of selected structures morphometry was performed to all study subjects and the MRPI was calculated for each selected patient. MRI midbrain area as well as superior cerebellar peduncle width were significantly lower in PSP patients compared to VP subjects. MRPI was significantly larger in PSP patients compared to VP subjects. MRPI value ≥13 distinguished the two groups with a sensitivity of 100 % (95 % CI 69.9-100) and a specificity of 100 % (95 % CI 77.1-100). MRPI may represent an accurate tool in differentiating PSP from VP.
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Mostile
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Alessandra
authors.initials: A
authors.lastname: Nicoletti
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Calogero Edoardo
authors.initials: CE
authors.lastname: Cicero
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Cavallaro
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Bruno
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Dibilio
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Antonina
authors.initials: A
authors.lastname: Luca
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Giorgia
authors.initials: G
authors.lastname: Sciacca
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Loredana
authors.initials: L
authors.lastname: Raciti
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Donatella
authors.initials: D
authors.lastname: Contrafatto
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy.
authors.forename: Ignazio
authors.initials: I
authors.lastname: Chiaramonte
authors.affiliation: Sezione di Neuroscienze, Dipartimento GF Ingrassia, Università degli Studi di Catania, Via S. Sofia 78, 95123, Catania, Italy. m.zappia@unict.it.
authors.forename: Mario
authors.initials: M
authors.lastname: Zappia
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D020734:Parkinsonian Disorders / Q000000981:diagnostic imaging*; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012720:Severity of Illness Index; D013494:Supranuclear Palsy, Progressive / Q000000981:diagnostic imaging*
keywords: Magnetic resonance imaging morphometry; Magnetic resonance parkinsonism index; Progressive supranuclear palsy; Vascular parkinsonism
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