title: Utilization of computer-aided detection system in diagnosing unilateral maxillary sinusitis on panoramic radiographs.
abstract: OBJECTIVE
  It is unclear whether computer-aided detection (CAD) systems for panoramic radiography can help inexperienced dentists to diagnose maxillary sinusitis. The aim of this study was to clarify whether a CAD system for panoramic radiography can contribute to improved diagnostic performance for maxillary sinusitis by inexperienced dentists.
  
  
  METHODS
  The panoramic radiographs of 49 patients with maxillary sinusitis and 49 patients with healthy sinuses were evaluated in this study. The diagnostic performance of the CAD system was determined. 12 inexperienced dentists and 4 expert oral and maxillofacial radiologists observed the total of 98 panoramic radiographs and judged the presence or absence of maxillary sinusitis, under conditions with and without the support of the CAD system. The receiver operating characteristic curves of the two groups were compared.
  
  
  RESULTS
  The CAD system provided sensitivity of 77.6%, specificity of 69.4% and accuracy of 73.5%. The diagnostic performance of the inexperienced dentists increased with the support of the CAD system. When the inexperienced dentists diagnosed maxillary sinusitis with CAD support, the area under the curve (AUC) was significantly higher than that without CAD support. When the focus was only on panoramic radiographs in which CAD support led to a correct diagnosis, the AUC of the inexperienced dentists increased to an equivalent level to that of the experienced radiologists.
  
  
  CONCLUSIONS
  The CAD system supported the inexperienced dentists in diagnosing maxillary sinusitis on the panoramic radiographs. If the accuracy of the CAD system can be increased, the benefits of CAD support will be further enhanced.
authors.affiliation: 1 Department of Oral and Maxillofacial Radiology, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
authors.forename: Yasufumi
authors.initials: Y
authors.lastname: Ohashi
authors.affiliation: 1 Department of Oral and Maxillofacial Radiology, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Ariji
authors.affiliation: 2 Department of Oral Radiology, Asahi University School of Dentistry, Mizuho, Japan.
authors.forename: Akitoshi
authors.initials: A
authors.lastname: Katsumata
authors.affiliation: 3 Department of Intelligent Image Information, Graduate School of Medicine, Gifu University, Gifu, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Fujita
authors.affiliation: 1 Department of Oral and Maxillofacial Radiology, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
authors.forename: Miwa
authors.initials: M
authors.lastname: Nakayama
authors.affiliation: 1 Department of Oral and Maxillofacial Radiology, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
authors.forename: Motoki
authors.initials: M
authors.lastname: Fukuda
authors.affiliation: 1 Department of Oral and Maxillofacial Radiology, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
authors.forename: Michihito
authors.initials: M
authors.lastname: Nozawa
authors.affiliation: 1 Department of Oral and Maxillofacial Radiology, Aichi-Gakuin University School of Dentistry, Nagoya, Japan.
authors.forename: Eiichiro
authors.initials: E
authors.lastname: Ariji
mesh_terms: D000328:Adult; D019540:Area Under Curve; D016022:Case-Control Studies; D002983:Clinical Competence / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging; D015523:Maxillary Sinusitis / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012372:ROC Curve; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000706:statistics & numerical data*; D011862:Radiography, Panoramic / Q000706:statistics & numerical data*; D012680:Sensitivity and Specificity
keywords: computer-aided detection; maxillary sinusitis; panoramic radiography
references.citation: Eur Arch Otorhinolaryngol. 2016 Sep;273(9):2629-35
references.pmid: 26345241
references.citation: AJR Am J Roentgenol. 2004 Dec;183(6):1755-60
references.pmid: 15547223
references.citation: Dentomaxillofac Radiol. 1994 Aug;23(3):149-53
references.pmid: 7835515
references.citation: Med Mycol. 2009;47 Suppl 1:S324-30
references.pmid: 19330659
references.citation: Dentomaxillofac Radiol. 1993 May;22(2):86-92
references.pmid: 8375560
references.citation: Dentomaxillofac Radiol. 1990 Feb;19(1):13-7
references.pmid: 2387471
references.citation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1998 Apr;85(4):479-84
references.pmid: 9574961
references.citation: Med Phys. 2000 Jan;27(1):47-55
references.pmid: 10659737
references.citation: J Craniomaxillofac Surg. 2015 Oct;43(8):1522-9
references.pmid: 26319958
references.citation: Case Rep Otolaryngol. 2014;2014:478092
references.pmid: 25057422
references.citation: Int J Tuberc Lung Dis. 2013 Dec;17(12):1613-20
references.pmid: 24200278
references.citation: J Craniomaxillofac Surg. 2013 Dec;41(8):808-15
references.pmid: 23515071
references.citation: Oral Dis. 2015 Apr;21(3):335-41
references.pmid: 25135460
references.citation: Oncol Lett. 2014 Dec;8(6):2637-2641
references.pmid: 25360173
references.citation: Dentomaxillofac Radiol. 2007 Jan;36(1):28-33
references.pmid: 17329585
references.citation: Nihon Jibiinkoka Gakkai Kaiho. 2015 Jun;118(6):728-35
references.pmid: 26567387
references.citation: Chin Med Sci J. 2007 Sep;22(3):139-43
references.pmid: 17966160
references.citation: Insights Imaging. 2015 Feb;6(1):1-16
references.pmid: 25575868
references.citation: Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2004 Aug;98(2):223-31
references.pmid: 15316549
references.citation: Comput Med Imaging Graph. 2003 Nov-Dec;27(6):497-502
references.pmid: 14575784