title: Magnetic solid phase extraction using ionic liquid-coated core-shell magnetic nanoparticles followed by high-performance liquid chromatography for determination of Rhodamine B in food samples.
abstract: Three hydrophobic ionic liquids (ILs) (1-butyl-3-methylimidazole hexafluorophosphate ([BMIM]PF6), 1-hexyl-3-methyl-imidazole hexafluoro-phosphate ([HMIM]PF6), and 1-octyl-3-methylimidazole hexafluorophosphate ([OMIM]PF6)) were used to coat Fe3O4@SiO2 nanoparticles (NPs) with core-shell structures to prepare magnetic solid phase extraction (MSPE) agents (Fe3O4@SiO2@IL). A novel method of MSPE coupled with high-performance liquid chromatography for the separation/analysis of Rhodamine B was then established. The results showed that Rhodamine B was adsorbed rapidly on Fe3O4@SiO2@[OMIM]PF6 and was released using ethanol. Under optimal conditions, the pre-concentration factor for the proposed method was 25. The linear range, limit of detection (LOD), correlation coefficient (R), and relative standard deviation (RSD) were found to be 0.50-150.00 μgL(-1), 0.08 μgL(-1), 0.9999, and 0.51% (n=3, c=10.00 μgL(-1)), respectively. The Fe3O4@SiO2 NPs could be re-used up to 10 times. The method was successfully applied to the determination of Rhodamine B in food samples.
authors.affiliation: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, PR China.
authors.forename: Jieping
authors.initials: J
authors.lastname: Chen
authors.affiliation: College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, PR China. Electronic address: xszhu@yzu.edu.cn.
authors.forename: Xiashi
authors.initials: X
authors.lastname: Zhu
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D052578:Ionic Liquids / Q000737:chemistry*; D008280:Magnetics / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D012235:Rhodamines / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D052578:Ionic Liquids; D058185:Magnetite Nanoparticles; D012235:Rhodamines; D012822:Silicon Dioxide; C029773:rhodamine B
keywords: 1-Bromohexane (PubChem CID: 8101); 1-Bromooctane (PubChem CID: 8140); Ethanol (PubChem CID: 702); FeCl(3) (PubChem CID: 24380); High-performance liquid chromatography; Ionic liquid-loaded magnetic nanoparticle; Magnetic solid phase extraction; Methanol (PubChem CID: 887); Methylene chloride (PubChem CID: 6344); N-Butyl bromide (PubChem CID: 74236); Potassium hexafluorophosphate (PubChem CID: 23688904); Rhodamine B; Rhodamine B (PubChem CID: 6694); Tetraethyl orthosilicate (PubChem CID: 6517)