title: Particle size distribution of aerosols sprayed from household hand-pump sprays containing fluorine-based and silicone-based compounds.
abstract: Japan has published safety guideline on waterproof aerosol sprays. Furthermore, the Aerosol Industry Association of Japan has adopted voluntary regulations on waterproof aerosol sprays. Aerosol particles of diameter less than 10 µm are considered as "fine particles". In order to avoid acute lung injury, this size fraction should account for less than 0.6% of the sprayed aerosol particles. In contrast, the particle size distribution of aerosols released by hand-pump sprays containing fluorine-based or silicone-based compounds have not been investigated in Japan. Thus, the present study investigated the aerosol particle size distribution of 16 household hand-pump sprays. In 4 samples, the ratio of fine particles in aerosols exceeded 0.6%. This study confirmed that several hand-pump sprays available in the Japanese market can spray fine particles. Since the hand-pump sprays use water as a solvent and their ingredients may be more hydrophilic than those of aerosol sprays, the concepts related to the safety of aerosol-sprays do not apply to the hand pump sprays. Therefore, it may be required for the hand-pump spray to develop a suitable method for evaluating the toxicity and to establish the safety guideline.
authors.forename: Tsuyoshi
authors.initials: T
authors.lastname: Kawakami
authors.forename: Kazuo
authors.initials: K
authors.lastname: Isama
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ikarashi
mesh_terms: D055371:Acute Lung Injury / Q000139:chemically induced; D000336:Aerosols; D017611:Fluorine Compounds / Q000737:chemistry* / Q000633:toxicity; D006795:Household Products / Q000633:toxicity; D007564:Japan; D010316:Particle Size; D017655:Silicon Compounds / Q000737:chemistry* / Q000633:toxicity
chemical_list: D000336:Aerosols; D017611:Fluorine Compounds; D017655:Silicon Compounds