title: New oral anticoagulants - a guide for ENT surgeons.
abstract: BACKGROUND
  New oral anticoagulants have been developed to overcome the perceived disadvantages of more traditional anticoagulants such as heparin and warfarin, and their use amongst ENT patients have been increasing.
  
  
  OBJECTIVE
  This review article aims to discuss the mechanism of action of new oral anticoagulants, when they should be used and a protocol for their use, in both the bleeding patient and in the peri-operative setting.
  
  
  CONCLUSIONS
  It is important that ENT surgeons are aware of the use of new oral anticoagulants, and have a departmental- and trust-based policy on their use and reversal in bleeding and surgical patients.
authors.affiliation: ENT Department,John Radcliffe Hospital,Oxford,UK.
authors.forename: S
authors.initials: S
authors.lastname: Kumar
authors.affiliation: ENT Department,Wexham Park Hospital,Slough,UK.
authors.forename: R
authors.initials: R
authors.lastname: Moorthy
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D006470:Hemorrhage / Q000188:drug therapy*; D006801:Humans; D013517:Otorhinolaryngologic Surgical Procedures / Q000592:standards*; D017410:Practice Guidelines as Topic
chemical_list: D000925:Anticoagulants
keywords: Antithrombins; Factor Xa Inhibitors; Hemorrhage