title: Image fusion and navigation platforms for percutaneous image-guided interventions.
abstract: Image-guided interventional procedures, particularly image guided biopsy and ablation, serve an important role in the care of the oncology patient. The need for tumor genomic and proteomic profiling, early tumor response assessment and confirmation of early recurrence are common scenarios that may necessitate successful biopsies of targets, including those that are small, anatomically unfavorable or inconspicuous. As image-guided ablation is increasingly incorporated into interventional oncology practice, similar obstacles are posed for the ablation of technically challenging tumor targets. Navigation tools, including image fusion and device tracking, can enable abdominal interventionalists to more accurately target challenging biopsy and ablation targets. Image fusion technologies enable multimodality fusion and real-time co-displays of US, CT, MRI, and PET/CT data, with navigational technologies including electromagnetic tracking, robotic, cone beam CT, optical, and laser guidance of interventional devices. Image fusion and navigational platform technology is reviewed in this article, including the results of studies implementing their use for interventional procedures. Pre-clinical and clinical experiences to date suggest these technologies have the potential to reduce procedure risk, time, and radiation dose to both the patient and the operator, with a valuable role to play for complex image-guided interventions.
authors.affiliation: Department of Diagnostic and Interventional Imaging, University of Texas Medical Center at Houston, 6431 Fannin Street, 2.130B, Houston, TX, 77030, USA.
authors.forename: Manoj
authors.initials: M
authors.lastname: Rajagopal
authors.affiliation: Section of Abdominal Imaging, Department of Diagnostic Radiology, University of Texas MD Anderson Cancer Center, 1400 Pressler St., Unit 1473, Pickens Tower, FCT 15.6074, Houston, TX, 77030-4009, USA. avenkatesan@mdanderson.org.
authors.forename: Aradhana M
authors.initials: AM
authors.lastname: Venkatesan
mesh_terms: D000818:Animals; D017115:Catheter Ablation / Q000379:methods*; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods*; D009369:Neoplasms / Q000473:pathology* / Q000601:surgery*; D015641:Radiography, Interventional / Q000379:methods*; D025321:Surgery, Computer-Assisted / Q000379:methods*
keywords: Electromagnetic (EM) tracking; Image-guided interventions; Navigation; Needle biopsy; Tumor ablation