title: A bioluminescent sensor for highly selective and sensitive detection of human carboxylesterase 1 in complex biological samples.
abstract: A highly selective and sensitive bioluminescent sensor (DME) for human carboxylesterase 1 (hCE1) has been developed and well characterized. DME could be used for real-time monitoring of hCE1 activities in complex biological samples and for bio-imaging of endogenous hCE1 in living cells.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn ylingdicp@gmail.com.
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Wang
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn ylingdicp@gmail.com.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Jin
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn ylingdicp@gmail.com.
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Zou
authors.affiliation: Dalian Medical University, Dalian, 116044, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Hou
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn ylingdicp@gmail.com.
authors.forename: Xia
authors.initials: X
authors.lastname: Lv
authors.affiliation: Dalian Medical University, Dalian, 116044, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Lei
authors.affiliation: Cancer Institute, The Second Hospital of Dalian Medical University, Dalian, China.
authors.forename: Hai-Ling
authors.initials: HL
authors.lastname: Cheng
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn ylingdicp@gmail.com.
authors.forename: Guang-Bo
authors.initials: GB
authors.lastname: Ge
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn ylingdicp@gmail.com.
authors.forename: Ling
authors.initials: L
authors.lastname: Yang
mesh_terms: D002265:Carboxylic Ester Hydrolases / Q000378:metabolism*; D057230:Limit of Detection; D049449:Luminescence
chemical_list: D002265:Carboxylic Ester Hydrolases