title: Molecular Pathology of Ovarian Carcinomas.
abstract: This content presents a review of molecular pathology of ovarian cancer. The authors present key molecular features for high-grade and low-grade serous carcinomas, endometrioid carcinomas, clear cell carcinomas, and mucinous carcinomas. Cell lineage, mutation and gene expression, pathway alterations, risk factors, prognostic markers, and treatment targets are discussed.
authors.affiliation: Department of Pathology, University of Calgary and Calgary Laboratory Services, Foothills Medical Centre, 1403 29 ST NW, Calgary, Alberta, Canada T2N 2T9. Electronic address: Martin.Kobel@cls.ab.ca.
authors.forename: Martin
authors.initials: M
authors.lastname: Köbel
authors.affiliation: Faculty of Medicine, Department of Pathology and Laboratory Medicine, University of British Columbia, BC Cancer Agency, #3427-600 West 10th Avenue, Vancouver, British Columbia V5Z 4E6, Canada.
authors.forename: David
authors.initials: D
authors.lastname: Huntsman
keywords: Cell of origin; Molecular pathology; Molecular therapeutic targets; Ovarian cancer; Prognostic markers