title: Innate immune signaling in CLL.
abstract: In this issue of Blood, Wagner et al describe a complex signaling model that explains the mechanism of action of a long-known prognostic marker in chronic lymphocytic leukemia (CLL) and integrates its function with the innate immune system and B-cell receptor signaling.
authors.affiliation: MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER.
authors.forename: Marcela V
authors.initials: MV
authors.lastname: Maus
mesh_terms: D056704:Adaptive Immunity; D006801:Humans; D007113:Immunity, Innate; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000276:immunology*; D051746:ZAP-70 Protein-Tyrosine Kinase / Q000276:immunology*
chemical_list: D051746:ZAP-70 Protein-Tyrosine Kinase