title: Molecular Classification of Breast Cancer.
abstract: This article reviews the conceptual and practical implications of the intrinsic subtype classification of breast cancers and the limitations of this approach. It presents the most extensively validated gene expression assays proposed as predictors of clinical outcome and discusses their potential clinical utility and limitations.
authors.affiliation: Division of Medical Oncology, Fred Hutchinson Cancer Research Center, University of Washington, 825 Eastlake Avenue East, G3630, Seattle, WA 98109-1023, USA.
authors.forename: Robin L
authors.initials: RL
authors.lastname: Jones
authors.affiliation: Division of Molecular Pathology, Institute of Cancer Research, 15 Cotswold Road, Sutton SM2 5NG, United Kingdom.
authors.forename: Anastasia
authors.initials: A
authors.lastname: Constantinidou
authors.affiliation: Department of Pathology, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10065, United States. Electronic address: jsreis@hotmail.com.
authors.forename: Jorge S
authors.initials: JS
authors.lastname: Reis-Filho