title: Overcoming Challenges With Statin Therapy.
authors.affiliation: Stroke Prevention & Atherosclerosis Research Centre, Robarts Research Institute, Western University, London, Ontario, Canada (D.S.) Division of Clinical Pharmacology, Department of Medicine, Western University, London, Ontario, Canada (D.S., G.K.D.).
authors.forename: J David
authors.initials: JD
authors.lastname: Spence
authors.affiliation: Division of Clinical Pharmacology, Department of Medicine, Western University, London, Ontario, Canada (D.S., G.K.D.).
authors.forename: George K
authors.initials: GK
authors.lastname: Dresser
mesh_terms: D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood / Q000209:etiology / Q000517:prevention & control*; D003920:Diabetes Mellitus / Q000139:chemically induced*; D004347:Drug Interactions; D057915:Drug Substitution; D050171:Dyslipidemias / Q000097:blood / Q000150:complications / Q000188:drug therapy*; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000009:adverse effects* / Q000493:pharmacokinetics; D007333:Insulin Resistance; D008055:Lipids / Q000097:blood*; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D009135:Muscular Diseases / Q000139:chemically induced*; D010597:Pharmacogenetics; D010818:Practice Patterns, Physicians'; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D008055:Lipids
keywords: Persistence; adverse effects; mitochondrial function; statins; ubiquinone
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