title: Pre-surgical regional blocks in orthognathic surgery: prospective study evaluating their influence on the intraoperative use of anaesthetics and blood pressure control.
abstract: In orthognathic surgery, maxillary (CNV2) and mandibular (CNV3) divisions of the trigeminal nerve can be blocked successfully prior to surgery. In this study, it was hypothesized that regional blocks (nerve block over a particular region: bilateral CNV2 and CNV3 divisions of the trigeminal nerve) would decrease the total requirement for intraoperative anaesthetic agents and facilitate the process of hypotensive anaesthesia. Local anaesthesia containing 1/100,000 epinephrine and 10ml 0.5% levobupivacaine was injected into the planned incisions in 50 patients. Twenty-five patients (group A) underwent orthognathic surgery without regional blocks and another 25 patients (group B) underwent surgery with regional blocks. The anaesthetic protocol was the same in both groups and administered by a single anaesthesiologist. The mean arterial pressure was recorded at several points throughout the operation, as well as all the medications used. The blood loss and the amounts of medications administered were lower in group B than in group A. In patients receiving regional blocks, the amounts of fentanyl and nicardipine required were significantly lower. The use of pre-emptive anaesthesia in orthognathic surgery may reduce the overall amounts of medications required for hypotensive anaesthesia, facilitate the intraoperative control of blood pressure, and decrease intraoperative blood loss.
authors.affiliation: Craniofacial Centre, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Craniofacial Research Centre, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Y A
authors.initials: YA
authors.lastname: Chen
authors.affiliation: Craniofacial Centre, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Craniofacial Research Centre, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: C M
authors.initials: CM
authors.lastname: Rivera-Serrano
authors.affiliation: Department of Anaesthesiology, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: C
authors.initials: C
authors.lastname: Chen
authors.affiliation: Craniofacial Centre, Chang Gung Memorial Hospital, Taoyuan, Taiwan; Craniofacial Research Centre, Chang Gung Memorial Hospital, Linkou, Taiwan. Electronic address: uraychen@cgmh.org.tw.
authors.forename: Y R
authors.initials: YR
authors.lastname: Chen
mesh_terms: D000328:Adult; D000766:Anesthesia, Dental; D000777:Anesthetics; D001794:Blood Pressure; D002045:Bupivacaine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D004837:Epinephrine / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D000077554:Levobupivacaine; D008297:Male; D009407:Nerve Block / Q000379:methods*; D057909:Orthognathic Surgery; D011446:Prospective Studies; D014276:Trigeminal Nerve
chemical_list: D000777:Anesthetics; D000077554:Levobupivacaine; D002045:Bupivacaine; D004837:Epinephrine
keywords: orthognathic surgery; pre-emptive analgesia; regional block