title: Accuracy of intra-operative frozen section in the diagnosis of female genital tract neoplasms.
abstract: OBJECTIVE
  To evaluate the accuracy of intra-operative frozen section in the diagnosis of various pelvic neoplasms, including ovarian tumours.
  
  
  METHODS
  The retrospective study was conducted at Shifa International Hospital and comprised records of all patients with lesions of female genital tract who underwent frozen section between January 2010 and December 2012. Comparison was made with the final diagnosis after histopathology was performed on examining permanent paraffin sections.
  
  
  RESULTS
  The mean age of the 54 patients was 43.70+/-14.8 years (range: 19-75 years). The frozen section was accurate in 51(92.6%) cases. It had a moderately high sensitivity of 75%, high specificity of 97.6%, high positive predictive value of 90% and high negative predictive value of 93.2%. Lack of agreement was found in cases of ovarian tumours of the mucinous and borderline variety.
  
  
  CONCLUSIONS
  Frozen section showed a considerable level of accuracy when dealing with suspected pelvic neoplasms.
authors.affiliation: Department of Histopathology, Shifa international Hospital, Islamabad.
authors.forename: Asna Haroon
authors.initials: AH
authors.lastname: Khan
authors.affiliation: Department of Histopathology, Shifa International Hospital, Islamabad.
authors.forename: Nadira
authors.initials: N
authors.lastname: Mamoon
authors.affiliation: Department of Histopathology, Shifa International Hospital, Islamabad.
authors.forename: Mariam
authors.initials: M
authors.lastname: Usman
authors.affiliation: Shifa College of Medicine, Islamabad.
authors.forename: Umme Salma
authors.initials: US
authors.lastname: Laleka
authors.affiliation: Services Institute of Medical Sciences, Services Hospital, Lahore.
authors.forename: Bilal
authors.initials: B
authors.lastname: Malik
mesh_terms: D000328:Adult; D005260:Female; D005629:Frozen Sections / Q000379:methods*; D005833:Genital Neoplasms, Female / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010386:Pelvic Neoplasms / Q000473:pathology*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D013048:Specimen Handling / Q000379:methods
keywords: Frozen section, Ovarian neoplasm, Paraffin, Diagnosis.