title: Synthesis of multi-functionalized benzofurans through the condensation of ninhydrin and phenols using SSA as a recyclable heterogeneous acid catalyst.
abstract: A simple and efficient one-pot methodology has been developed for the synthesis of biologically important multi-functionalized 3-(2[Formula: see text]-hydroxyaryl)-2-(2[Formula: see text]-carboxyphenyl)benzofurans using silica sulfuric acid (SSA) as a heterogeneous acid catalyst in DMF medium. The significant advantages of this methodology are the use of SSA as a recyclable solid acid catalyst, operational simplicity, easy availability of the starting materials, and good yield of the products with high atom-economy.
authors.affiliation: Department of Chemistry, University of Calcutta, 92, A. P. C. Road, Kolkata, 700 009, India.
authors.forename: Ashis
authors.initials: A
authors.lastname: Kundu
authors.affiliation: Department of Chemistry, University of Calcutta, 92, A. P. C. Road, Kolkata, 700 009, India. animesh_in2001@yahoo.co.in.
authors.forename: Animesh
authors.initials: A
authors.lastname: Pramanik
mesh_terms: D001572:Benzofurans / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D015394:Molecular Structure; D009555:Ninhydrin / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D013464:Sulfuric Acids / Q000737:chemistry
chemical_list: D001572:Benzofurans; D010636:Phenols; D013464:Sulfuric Acids; D012822:Silicon Dioxide; D009555:Ninhydrin; C033158:sulfuric acid
keywords: Benzofurans; Condensation reaction; Ninhydrin; Phenols; Silica sulfuric acid
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