title: The European Hematology Association Roadmap for European Hematology Research: a consensus document.
abstract: The European Hematology Association (EHA) Roadmap for European Hematology Research highlights major achievements in diagnosis and treatment of blood disorders and identifies the greatest unmet clinical and scientific needs in those areas to enable better funded, more focused European hematology research. Initiated by the EHA, around 300 experts contributed to the consensus document, which will help European policy makers, research funders, research organizations, researchers, and patient groups make better informed decisions on hematology research. It also aims to raise public awareness of the burden of blood disorders on European society, which purely in economic terms is estimated at €23 billion per year, a level of cost that is not matched in current European hematology research funding. In recent decades, hematology research has improved our fundamental understanding of the biology of blood disorders, and has improved diagnostics and treatments, sometimes in revolutionary ways. This progress highlights the potential of focused basic research programs such as this EHA Roadmap.The EHA Roadmap identifies nine 'sections' in hematology: normal hematopoiesis, malignant lymphoid and myeloid diseases, anemias and related diseases, platelet disorders, blood coagulation and hemostatic disorders, transfusion medicine, infections in hematology, and hematopoietic stem cell transplantation. These sections span 60 smaller groups of diseases or disorders.The EHA Roadmap identifies priorities and needs across the field of hematology, including those to develop targeted therapies based on genomic profiling and chemical biology, to eradicate minimal residual malignant disease, and to develop cellular immunotherapies, combination treatments, gene therapies, hematopoietic stem cell treatments, and treatments that are better tolerated by elderly patients.
authors.affiliation: Universität zu Köln, Cologne, Germany a.engert@uni-koeln.de.
authors.forename: Andreas
authors.initials: A
authors.lastname: Engert
authors.affiliation: IRCCS Policlinico San Matteo Foundation, Pavia, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Balduini
authors.affiliation: Leids Universitair Medisch Centrum, Leiden, the Netherlands.
authors.forename: Anneke
authors.initials: A
authors.lastname: Brand
authors.affiliation: Université Claude Bernard, Lyon, France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Coiffier
authors.affiliation: Hôpitaux Universitaires Henri Mondor, Créteil, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Cordonnier
authors.affiliation: Universitätsklinikum Ulm, Germany.
authors.forename: Hartmut
authors.initials: H
authors.lastname: Döhner
authors.affiliation: European Hematology Association, The Hague, the Netherlands.
authors.forename: Thom Duyvené
authors.initials: TD
authors.lastname: de Wit
authors.affiliation: Medizinische Universität Wien, Vienna, Austria.
authors.forename: Sabine
authors.initials: S
authors.lastname: Eichinger
authors.affiliation: Leids Universitair Medisch Centrum, Leiden, the Netherlands.
authors.forename: Willem
authors.initials: W
authors.lastname: Fibbe
authors.affiliation: Cambridge Institute for Medical Research, United Kingdom.
authors.forename: Tony
authors.initials: T
authors.lastname: Green
authors.affiliation: European Hematology Association, The Hague, the Netherlands.
authors.forename: Fleur
authors.initials: F
authors.lastname: de Haas
authors.affiliation: Università Federico II di Napoli, Italy.
authors.forename: Achille
authors.initials: A
authors.lastname: Iolascon
authors.affiliation: Université Pierre et Marie Curie, Paris, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Jaffredo
authors.affiliation: Ospedale San Bortolo, Vicenza, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Rodeghiero
authors.affiliation: Hospices Civils de Lyon/Université de Lyon, Pierre-Bénite, France.
authors.forename: Gilles
authors.initials: G
authors.lastname: Salles
authors.affiliation: Universitair Medisch Centrum Groningen, the Netherlands.
authors.forename: Jan Jacob
authors.initials: JJ
authors.lastname: Schuringa
mesh_terms: D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000627:therapeutic use; D001777:Blood Coagulation / Q000187:drug effects; D003131:Combined Modality Therapy / Q000191:economics / Q000379:methods*; D005060:Europe; D020869:Gene Expression Profiling; D015316:Genetic Therapy / Q000191:economics / Q000379:methods*; D015894:Genome, Human; D006299:Health Services for the Aged / Q000600:supply & distribution; D006402:Hematologic Diseases / Q000175:diagnosis* / Q000191:economics / Q000473:pathology / Q000628:therapy*; D006405:Hematology / Q000191:economics / Q000379:methods*; D006410:Hematopoiesis / Q000187:drug effects / Q000235:genetics; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods; D006801:Humans; D058990:Molecular Targeted Therapy / Q000191:economics / Q000379:methods*
chemical_list: D000970:Antineoplastic Agents
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