title: Factors Affecting Survival in Patients with Colorectal Cancer in Shiraz, Iran.
abstract: BACKGROUND
  Colorectal cancer (CRC) is the third most common cancer in the world, and the fourth in Iran in both genders. The aim of this study was to find predictive factors for CRC survival.
  
  
  METHODS
  Medical records of 570 patients referred to the radiotherapy oncology department of Shiraz Namazi hospital from 2005 to 2010 were retrospectively analysed. Data were collected by reviewing medical records, and by telephone interviews with patients. Survival analysis was performed using the Cox's regression model with survival probability estimated with Kaplan-Meier curve. The log-rank test was used to compare survival between strata. Data was analyzed with Stata 12.
  
  
  RESULTS
  The five-year survival rate and the mean survival time after cancer diagnosis were 58.5% and 67±1.4 months. On multivariate analysis, age of diagnosis, disease stage and primary tumor site, lymphovascular invasion and type of treatment (in colon cancer) were significant factors for survival.
  
  
  CONCLUSIONS
  Age of diagnosis and type of treatment (adjuvant therapy in patients with colon cancer) were two modifiable factors related to survival of CRC patients. Therefore earlier diagnosis might help increase survival.
authors.affiliation: Department of Epidemiology and Biostatistics, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran E-mail : n_khanjani@kmu.ac.ir.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Zare-Bandamiri
authors.forename: Narges
authors.initials: N
authors.lastname: Khanjani
authors.forename: Yunes
authors.initials: Y
authors.lastname: Jahani
authors.forename: Mohammad
authors.initials: M
authors.lastname: Mohammadianpanah
mesh_terms: D015179:Colorectal Neoplasms / Q000401:mortality* / Q000473:pathology*; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D006801:Humans; D007492:Iran; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods; D011379:Prognosis; D012189:Retrospective Studies; D015996:Survival Rate