title: Fertility preservation for boys and adolescents facing sterilizing medical therapy.
abstract: Improvements in childhood cancer survival have allowed boys and their families to increasingly focus on quality of life after therapy, particularly their future ability to father children. Treatments should maintain comprehensive cancer care goals and consider the long-term quality of life of these children. While semen cryopreservation is a well-established method of fertility preservation for post-pubertal children, the use of cryopreserved pre-treatment testicular tissue represents a promising, yet experimental method of fertility preservation for prepubertal males facing sterilizing therapy. Healthcare providers should counsel families about the fertility risks of therapy, discuss or refer patients for standard fertility preservation options, and consider experimental approaches to fertility preservation while being mindful of the ethical questions these treatments raise.
authors.affiliation: 1 Department of Urology, University of California, San Francisco, CA, USA ; 2 Department of Urology, Cairo University, Egypt ; 3 Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA ; 4 Philip R. Lee Institute for Health Policy Studies, San Francisco, CA, USA.
authors.forename: Ahmed A
authors.initials: AA
authors.lastname: Hussein
authors.affiliation: 1 Department of Urology, University of California, San Francisco, CA, USA ; 2 Department of Urology, Cairo University, Egypt ; 3 Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA ; 4 Philip R. Lee Institute for Health Policy Studies, San Francisco, CA, USA.
authors.forename: Nam D
authors.initials: ND
authors.lastname: Tran
authors.affiliation: 1 Department of Urology, University of California, San Francisco, CA, USA ; 2 Department of Urology, Cairo University, Egypt ; 3 Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA ; 4 Philip R. Lee Institute for Health Policy Studies, San Francisco, CA, USA.
authors.forename: James F
authors.initials: JF
authors.lastname: Smith
keywords: Fertility preservation; boys; cancer; malignancy
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