title: Robot-assisted partial nephrectomy in 95 consecutive patients: Oncological and functional outcomes at 3 years of follow-up.
abstract: BACKGROUND
  We present the oncological and functional results from a series of 43 patients with renal tumours, treated consecutively with robot-assisted partial nephrectomy (RPN).
  
  
  METHODS
  Between 2010 and 2014, we performed 95 RPNs. To assess the results, we included only those patients (n=43) who had a minimum follow-up of 2 years. A descriptive analysis was conducted of the demographic characteristics and perioperative variables. We employed Kaplan-Meier curves to assess overall survival, cancer-specific survival and recurrence-free survival.
  
  
  RESULTS
  The patients' mean age was 53.1±13.5 years. The mean preoperative tumour size was 3.7±2.3cm. The mean surgical time was 102.2±37.1min. The mean ischemia time was 21.27±7.74minutes, with a median intraoperative bleeding volume of 150mL (IQR, 87.5-425). There was a 7% rate of postoperative complications (Clavien≥III). There was no mortality. The average Fürhman grade was 2.5±0.56. There were no positive surgical margins or local recurrences. The median follow-up was 38±8 months, with an overal survival, recurrence-free survival and cancer-specific survival of 100% at 3 years of follow-up. The recurrence-free survival was 92,3% at 48 months of follow-up. The mean preoperative glomerular filtration rate was 91.04±28.17mL/min/1.73m(2), and the postoperative rate was 89.9±27.69mL/min/1.73m(2), with a nonsignificant reduction (P=.74).
  
  
  CONCLUSIONS
  The functional and oncological results of our series confirm the safety and efficacy of RPN. RPN offers optimal preservation of renal function and oncological control in the medium term.
authors.affiliation: Unidad de Urología y Centro de Cirugía Robótica, Clínica INDISA; Facultad de Medicina, Universidad Andrés Bello. Electronic address: octavio.castillo@indisa.cl.
authors.forename: O A
authors.initials: OA
authors.lastname: Castillo
authors.affiliation: Unidad de Urología y Centro de Cirugía Robótica, Clínica INDISA.
authors.forename: A
authors.initials: A
authors.lastname: Rodríguez-Carlin
authors.affiliation: Unidad de Urología y Centro de Cirugía Robótica, Clínica INDISA.
authors.forename: V
authors.initials: V
authors.lastname: Borgna
mesh_terms: D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D020127:Recovery of Function; D012189:Retrospective Studies; D065287:Robotic Surgical Procedures; D013997:Time Factors; D016896:Treatment Outcome
keywords: Carcinoma de células renales; Cirugía conservadora de nefronas; Conservative nephron surgery; Nefrectomía parcial robótica; Oncological results; Renal cell carcinomas; Resultados oncológicos; Robot-assisted partial nephrectomy