title: Pregnancy-Associated "Cutaneous Type" Pemphigus Vulgaris.
abstract: The development of pemphigus, including pemphigus vulgaris (PV) and pemphigus foliaceus, during pregnancy is rare. PV manifests with mucosal and/or cutaneous erosions with flaccid bullae that are histologically characterized by suprabasilar acantholysis. In contrast, pemphigus foliaceus manifests with cutaneous-only involvement and superficial epidermal acantholysis. Enzyme-linked immunosorbent assay specific for autoantibodies against desmoglein 1 and desmoglein 3 aids in the diagnosis and differentiation between pemphigus subtypes. High-dose systemic corticosteroids are first-line agents in management of PV, yet their potential long-term use raises complex management issues associated with pregnancy and fetal risk. Here we report a rare case of cutaneous-limited PV in association with pregnancy.
authors.affiliation: Dermatologist in the Department of Dermatology at the Roseville Medical Center in CA. rangelj@alumni.ucsf.edu.
authors.forename: Javier
authors.initials: J
authors.lastname: Rangel
mesh_terms: D000279:Administration, Cutaneous; D005260:Female; D006801:Humans; D008875:Middle Aged; D010392:Pemphigus / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*; D011247:Pregnancy; D016896:Treatment Outcome
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