title: Surface characterization and in vivo evaluation of laser sintered and machined implants followed by resorbable-blasting media process: A study in sheep.
abstract: BACKGROUND
  This study aimed to compare the histomorphometric and histological bone response to laser-sintered implants followed by resorbable-blasting media (RBM) process relative to standard machined/RBM surface treated implants.
  
  
  METHODS
  Six male sheep (n=6) received 2 Ti-6Al-4V implants (1 per surface) in each side of the mandible for 6 weeks in vivo. The histomorphometric parameters bone-implant contact (BIC) and bone area fraction occupancy (BAFO) were evaluated.
  
  
  RESULTS
  Optical interferometry revealed higher Sa and Sq values for the laser-sintered/RBM surface in relation to standard/RBM implants. No significant differences in BIC were observed between the two groups (p>0.2), but significantly higher BAFO was observed for standard/RBM implants (p<0.01).
  
  
  CONCLUSIONS
  The present study demonstrated that both surfaces were biocompatible and osseoconductive, and the combination of laser sintering and RBM has no advantage over the standard machined implants with subsequent RBM.
authors.affiliation: 345 E 24th Street, 10010, Biomaterials and Biomimetics, New York University, New York, NY, USA, rh1694@@nyu.edu.
authors.forename: Michelle
authors.initials: M
authors.lastname: Bowers
authors.forename: Daniel
authors.initials: D
authors.lastname: Yoo
authors.forename: Charles
authors.initials: C
authors.lastname: Marin
authors.forename: Luiz
authors.initials: L
authors.lastname: Gil
authors.forename: Nour
authors.initials: N
authors.lastname: Shabaka
authors.forename: Matt
authors.initials: M
authors.lastname: Goldstein
authors.forename: Malvin
authors.initials: M
authors.lastname: Janal
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
authors.forename: Ronaldo
authors.initials: R
authors.lastname: Hirata
authors.forename: Estevam
authors.initials: E
authors.lastname: Bonfante
authors.forename: Paulo
authors.initials: P
authors.lastname: Coelho
mesh_terms: D000818:Animals; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D007834:Lasers; D008297:Male; D016348:Osseointegration; D012756:Sheep; D013499:Surface Properties
chemical_list: D015921:Dental Implants
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