title: Opportunistic Screening of Vitamin B12 Deficiency in IT Professionals Presenting for Routine Health Check-up.
abstract: BACKGROUND
  Vitamin B12 deficiency is mainly diagnosed in symptomatic patients. However, the deficiency may also be prevalent in asymptomatic patients. Our aim was to study the prevalence of Vit B12 deficiency in IT professionals (Information Technology Professionals from Software industry) who presented for routine health screening and to correlate the deficiency to various parameters.
  
  
  METHODS
  This was single centre, observational study comprising of 84 IT professionals. The data was collected in structured format. The study was designed to identify prevalence of Vit B12 deficiency and correlate to other factors such as type of diet, income level & regular use of medication (such as Antacid & Metformin).
  
  
  RESULTS
  Total 28 individuals were found to be deficient (33.34%). Prevalence of Vit B12 deficiency amongst Vegetarian and non vegetarian diet adhering subjects was 47.5% and 20.45% respectively. B12 deficiency was also prevalent in high income age group. Further chronic intake of PPI (Proton pump inhibitor) and Metformin was associated with prevalence of 37.5% and 33.34% in the present study.
  
  
  CONCLUSIONS
  During health screening of IT Professionals, significant prevalence of Vit B12 deficiency was noted across all income groups & non vegetarian diet consuming subjects also. There is significant correlation between Vit B12 deficiency with chronic use of PPI and Metformin.
authors.affiliation: Associate Professor, Department of Medicine, SKN Medical College , Narhe, Sinhgad Road, Pune, India .
authors.forename: Jitendra Rajendra
authors.initials: JR
authors.lastname: Ingole
authors.affiliation: Associate Professor, Department of Medicine, SKN Medical College , Narhe, Sinhgad Road, Pune, India .
authors.forename: Rishi Devilal
authors.initials: RD
authors.lastname: Patel
authors.affiliation: Assistant Professor, Department of Obstetric and Gynecology, SKN Medical College , Narhe, Sinhgad Road, Pune, India .
authors.forename: Sonali Jitendra
authors.initials: SJ
authors.lastname: Ingole
authors.affiliation: Associate Professor, Department of PSM, SKN Medical College , Narhe, Sinhgad Road, Pune, India .
authors.forename: Harshal Tukaram
authors.initials: HT
authors.lastname: Pandave
keywords: Asymptomatic patients; Proton pump inhibitor; Serum Vitamin
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