title: Vertebral Hemangiomas and Their Correlation With Other Pathologies.
abstract: METHODS
  This cross-sectional study was carried out on 196 adults (98 men and 98 women), aged between 18 and 91 years.
  
  
  OBJECTIVE
  To examine whether vertebral hemangiomas (VHs) are associated with other spinal pathologies, metabolic diseases, cardiovascular diseases, cancer and past trauma, to shed light on their possible pathophysiology.
  
  
  BACKGROUND
  VHs are the most common form of benign tumors in the spine. Their association with spinal and systemic pathologies has not yet been systematically studied.
  
  
  METHODS
  Clinical data were gathered from full spine CT scans and medical records.
  
  
  RESULTS
  VHs were significantly associated with disc lesions (P = 0.004), past trauma (P = 0.037), diabetes (χ = 5.179, P = 0.023), cardio-vascular diseases (χ = 8.625, P = 0.003), and cancer (χ = 5.820, P = 0.016), but not with obesity. Only medium-large size VHs were significantly associated with osteoporosis (χ = 6.695, P = 0.010).
  
  
  CONCLUSIONS
  The pattern of diseases related to VHs suggests a common cause for VH, namely, a disruption of vascular flow in the microvessels (accompanied by endothelium damage) within the vertebral body, eventually resulting in hypervascularization.
  
  
  METHODS
  4.
authors.affiliation: *Department of Anatomy and Anthropology, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel †Department of Radiology, Carmel Medical Center, Haifa, Israel ‡Department of Physical Therapy, Zefat Academic College, Zefat, Israel.
authors.forename: Viviane
authors.initials: V
authors.lastname: Slon
authors.forename: Nathan
authors.initials: N
authors.lastname: Peled
authors.forename: Janan
authors.initials: J
authors.lastname: Abbas
authors.forename: Dan
authors.initials: D
authors.lastname: Stein
authors.forename: Haim
authors.initials: H
authors.lastname: Cohen
authors.forename: Israel
authors.initials: I
authors.lastname: Hershkovitz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001416:Back Pain / Q000150:complications / Q000453:epidemiology; D003430:Cross-Sectional Studies; D048909:Diabetes Complications / Q000453:epidemiology; D005260:Female; D006391:Hemangioma / Q000150:complications* / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000150:complications / Q000453:epidemiology; D013125:Spinal Neoplasms / Q000150:complications* / Q000453:epidemiology*; D055815:Young Adult