title: A Chronic Respiratory Pasteurella multocida Infection Is Well-Controlled by Long-Term Macrolide Therapy.
abstract: A 57-year-old woman with severe bronchiectasis frequently received antibiotics, including penicillin, for acute exacerbations due to Pasteurella multocida. Although the bacteria showed a decrease in antibiotic susceptibility, her symptoms and X-ray findings became stable, and severe exacerbations were not observed for the last few years after a low-dose erythromycin treatment was started. The development of a respiratory infection with Pasteurella multocida is relatively uncommon, but it can be controlled by immunomodulation which is associated with long-term macrolide therapy.
authors.affiliation: Division of Infection Control and Prevention, Osaka University Hospital, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Seki
authors.forename: Tomomi
authors.initials: T
authors.lastname: Sakata
authors.forename: Masahiro
authors.initials: M
authors.lastname: Toyokawa
authors.forename: Isao
authors.initials: I
authors.lastname: Nishi
authors.forename: Kazunori
authors.initials: K
authors.lastname: Tomono
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001987:Bronchiectasis / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D002908:Chronic Disease; D003371:Cough / Q000382:microbiology; D004334:Drug Administration Schedule; D004917:Erythromycin / Q000008:administration & dosage / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D018942:Macrolides / Q000008:administration & dosage / Q000627:therapeutic use*; D008875:Middle Aged; D010326:Pasteurella Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D016979:Pasteurella multocida / Q000187:drug effects*; D012141:Respiratory Tract Infections / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D018942:Macrolides; D004917:Erythromycin