title: A mitochondrial outer membrane-localized protein encoded by White spot syndrome virus.
abstract: White spot syndrome virus (WSSV) is a devastating pathogen of crustaceans that causes huge losses to global shrimp farming. In this study, a mitochondrial outer membrane protein encoded by WSSV, termed as wsv152, was identified. Bioinformatics analysis showed that wsv152 shared no similarity with any known proteins. Real-time RT-PCR revealed that wsv152 was initially transcribed at 6 h post WSSV infection. Fluorescent microscopy demonstrated that the wsv152-GFP fusion protein was present in the mitochondrion. Western blot further suggested that wsv152 was specifically localized on the outer membrane of mitochondria. To our knowledge, this is the first report of a mitochondrion-localized protein encoded by WSSV.
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China.
authors.forename: Muting
authors.initials: M
authors.lastname: Yan
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Liu
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China.|School of Marine Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
authors.forename: Qianhui
authors.initials: Q
authors.lastname: Liang
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China.
authors.forename: Jianhui
authors.initials: J
authors.lastname: He
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China.
authors.forename: Shaoping
authors.initials: S
authors.lastname: Weng
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China. lsshjg@mail.sysu.edu.cn.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China. lsshjg@mail.sysu.edu.cn.|School of Marine Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China. lsshjg@mail.sysu.edu.cn.
authors.forename: Jianguo
authors.initials: J
authors.lastname: He
authors.affiliation: State Key Laboratory for Biocontrol/MOE Key Laboratory of Aquatic Product Safety, School of Life Sciences, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China. xuxpeng@mail.sysu.edu.cn.|Institute of Aquatic Economic Animals and Guangdong Provice/Key Laboratory for Aquatic Economic Animals, Sun Yat-sen University, Guangzhou, People's Republic of China. xuxpeng@mail.sysu.edu.cn.
authors.forename: Xiaopeng
authors.initials: X
authors.lastname: Xu
mesh_terms: D000595:Amino Acid Sequence; D001483:Base Sequence; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism*; D016366:Open Reading Frames; D021381:Protein Transport; D014759:Viral Envelope Proteins / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D046848:White spot syndrome virus 1 / Q000235:genetics*
chemical_list: D008565:Membrane Proteins; D014759:Viral Envelope Proteins
keywords: Mitochondria; Mitochondrial outer membrane protein; WSSV; wsv152
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