title: Submicron magnetic core conducting polypyrrole polymer shell: Preparation and characterization.
abstract: Magnetic particles are of great interest in various biomedical applications, such as, sample preparation, in vitro biomedical diagnosis, and both in vivo diagnosis and therapy. For in vitro applications and especially in labs-on-a-chip, microfluidics, microsystems, or biosensors, the needed magnetic dispersion should answer various criteria, for instance, submicron size in order to avoid a rapid sedimentation rate, fast separations under an applied magnetic field, and appreciable colloidal stability (stable dispersion under shearing process). Then, the aim of this work was to prepare highly magnetic particles with a magnetic core and conducting polymer shell particles in order to be used not only as a carrier, but also for the in vitro detection step. The prepared magnetic seed dispersions were functionalized using pyrrole and pyrrole-2-carboxylic acid. The obtained core-shell particles were characterized in terms of particle size, size distribution, magnetization properties, FTIR analysis, surface morphology, chemical composition, and finally, the conducting property of those particles were evaluated by cyclic voltammetry. The obtained functional submicron highly magnetic particles are found to be conducting material bearing function carboxylic group on the surface. These promising conducting magnetic particles can be used for both transport and lab-on-a-chip detection.
authors.affiliation: University of Lyon, F-69622, Lyon, France, University Lyon-1, Villeurbanne, CNRS, UMR-5007, LAGEP-CPE, 43 Bd 11 Novembre 1918, F-69622 Villeurbanne, France; State University of Maringá, Department of Chemistry, Av. Colombo, 5790, CEP 87020-900 Maringá, Paraná, Brazil.
authors.forename: Ernandes Taveira
authors.initials: ET
authors.lastname: Tenório-Neto
authors.affiliation: Institut des Sciences Analytiques (ISA), Université Lyon, Université Claude Bernard Lyon-1, UMR-5180, 5 Rue de la Doua, F-69100 Villeurbanne, France.
authors.forename: Abdoullatif
authors.initials: A
authors.lastname: Baraket
authors.affiliation: Universiapolis, International University of Agadir, Technopole Agadir, Bab El Madina, 80000 Agadir, Morocco.
authors.forename: Dounia
authors.initials: D
authors.lastname: Kabbaj
authors.affiliation: Institut des Sciences Analytiques (ISA), Université Lyon, Université Claude Bernard Lyon-1, UMR-5180, 5 Rue de la Doua, F-69100 Villeurbanne, France.
authors.forename: Nadia
authors.initials: N
authors.lastname: Zine
authors.affiliation: Institut des Sciences Analytiques (ISA), Université Lyon, Université Claude Bernard Lyon-1, UMR-5180, 5 Rue de la Doua, F-69100 Villeurbanne, France.
authors.forename: Abdelhamid
authors.initials: A
authors.lastname: Errachid
authors.affiliation: University of Lyon, F-69622, Lyon, France, University Lyon-1, Villeurbanne, CNRS, UMR-5007, LAGEP-CPE, 43 Bd 11 Novembre 1918, F-69622 Villeurbanne, France.
authors.forename: Hatem
authors.initials: H
authors.lastname: Fessi
authors.affiliation: State University of Maringá, Department of Chemistry, Av. Colombo, 5790, CEP 87020-900 Maringá, Paraná, Brazil.
authors.forename: Marcos Hiroiuqui
authors.initials: MH
authors.lastname: Kunita
authors.affiliation: University of Lyon, F-69622, Lyon, France, University Lyon-1, Villeurbanne, CNRS, UMR-5007, LAGEP-CPE, 43 Bd 11 Novembre 1918, F-69622 Villeurbanne, France. Electronic address: Elaissari@lagep.univ-lyon1.fr.
authors.forename: Abdelhamid
authors.initials: A
authors.lastname: Elaissari
mesh_terms: D055664:Electrochemical Techniques; D008280:Magnetics; D046529:Microscopy, Electron, Transmission; D053758:Nanoparticles / Q000737:chemistry; D010316:Particle Size; D011108:Polymers / Q000737:chemistry*; D011392:Proline / Q000031:analogs & derivatives / Q000737:chemistry; D011758:Pyrroles / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties
chemical_list: D011108:Polymers; D011758:Pyrroles; C067635:polypyrrole; C002986:2-pyrrolecarboxylic acid; D011392:Proline
keywords: Encapsulation; Functionalization; Magnetic emulsion; Magnetic latex particles; Seed polymerization