title: [Hypertrophic cardiomyopathy with midventricular obstruction of the left ventricle (MVO)--case report].
abstract: A 76-year old woman with a history of stage 3 arterial hypertension, paroxysmal atrial fibrillation, hypercholesterolemia and type 2 diabetes mellitus. Ventricular tachycardia was the first clinical manifestation of the disease. Echocardiography revealed hypertrophic cardiomyopathy with a high intraventricular gradient of 47 mmHg and midventricular obstruction at the level of the papillary muscles (the lumen of the left ventricle was 1-2 mm during systole). No ventricular aneurysm was found but the ventricle was elongated and dilated in the periapical part where systolic function was decreased but synchronized in time. Coronary angiograms showed no narrowing of coronary arteries. A single-chamber cardioverter-defibrillator (ICD, implantable cardioverter-defibrillator) was implanted to prevent sudden cardiac death. Modified-release metoprolol and amiodarone were administered in antiarrhythmic therapy. This case represents a rare kind of hypertrophic cardiomyopathy in an elderly woman which is characterized by midventricular obstruction.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Pizoń
authors.forename: Marek
authors.initials: M
authors.lastname: Rajzer
authors.forename: Wiktoria
authors.initials: W
authors.lastname: Wojciechowska
authors.forename: Marek
authors.initials: M
authors.lastname: Jastrzebski
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Olszanecka
authors.forename: Marta
authors.initials: M
authors.lastname: Rojek
authors.forename: Artur
authors.initials: A
authors.lastname: Jurczyszyn
authors.forename: Danuta
authors.initials: D
authors.lastname: Czarnecka
mesh_terms: D000368:Aged; D000638:Amiodarone / Q000627:therapeutic use*; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis* / Q000628:therapy*; D017147:Defibrillators, Implantable; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D008790:Metoprolol / Q000627:therapeutic use*; D016896:Treatment Outcome; D014463:Ultrasonography; D014694:Ventricular Outflow Obstruction / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D008790:Metoprolol; D000638:Amiodarone