title: Three-Dimensional Volumetric Assessment of the Effect of Decompression on Large Mandibular Odontogenic Cystic Lesions.
abstract: OBJECTIVE
  The primary approach to treating large cystic lesions is controversial. The aims of the present study were to assess the effects of decompression before enucleation for the treatment of large cystic lesions and to compare the rate of decrease of keratocystic odontogenic tumor, ameloblastoma, and dentigerous cyst at specific times (preoperatively and at 6 months).
  
  
  METHODS
  The study included 40 patients (mean age, 31.22 ± 8.78 yr) with large mandibular lesions (>3 cm). Decompression was used to release intraluminal pressure and decrease the volume of the lesion. Three-dimensional computed tomography was applied to all patients at the diagnosis stage and at 6 months after decompression. Volumetric analysis was performed using software designed for 3-dimensional measurement of volumes. Other variables, such as age, gender, and rate of decrease, were recorded.
  
  
  RESULTS
  There were important differences in rates of decrease between preoperative and 6-month lesion volumes. Statistical analyses showed no significant differences among groups for age, gender, and histologic lesion type (P > .05).
  
  
  CONCLUSIONS
  Decompression of large cystic lesions could be useful for surgical interventions without complications.
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Afyon Kocatepe University, Afyonkarahisar, Turkey. Electronic address: dt_asutay@hotmail.com.
authors.forename: Fatih
authors.initials: F
authors.lastname: Asutay
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Atalay
authors.affiliation: Assistant Professor, Department of Anatomy, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Ozan
authors.initials: O
authors.lastname: Turamanlar
authors.affiliation: Researcher, Department of Anatomy, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Erdal
authors.initials: E
authors.lastname: Horata
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Yeditepe University, İstanbul, Turkey.
authors.forename: Muammer Çağrı
authors.initials: MÇ
authors.lastname: Burdurlu
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D019299:Decompression, Surgical / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009807:Odontogenic Cysts / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed; D055815:Young Adult