title: Elevated 68Ga Prostate-Specific Membrane Antigen Activity in Metastatic Non-Small Cell Lung Cancer.
abstract: A 71-year-old man with a background of treated stage IIIB non-small cell lung cancer was referred for Ga prostate-specific membrane antigen (PSMA) PET/CT for staging of prostate cancer. In addition to the PSMA uptake in the known prostate malignancy, the study also demonstrated increased PSMA uptake in an enlarging left lower lobe lung mass with diffusely increased PSMA uptake in an enlarged thyroid gland and bilateral enlarged supraclavicular lymph nodes. Fine-needle aspiration biopsy of the thyroid gland and a left supraclavicular lymph node demonstrated metastatic adenocarcinoma from a primary lung cancer.
authors.affiliation: From the *Department of Nuclear Medicine and PET, Nepean Hospital, Penrith; †Sydney Medical School Nepean, University of Sydney, and ‡Department of Oncology, Nepean Hospital, Penrith, New South Wales, Australia.
authors.forename: Deepa
authors.initials: D
authors.lastname: Shetty
authors.forename: Han
authors.initials: H
authors.lastname: Loh
authors.forename: Chuong
authors.initials: C
authors.lastname: Bui
authors.forename: Robert
authors.initials: R
authors.lastname: Mansberg
authors.forename: Amanda
authors.initials: A
authors.lastname: Stevanovic
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging / Q000556:secondary*; D000368:Aged; D002289:Carcinoma, Non-Small-Cell Lung / Q000378:metabolism / Q000473:pathology*; D004492:Edetic Acid / Q000031:analogs & derivatives; D005709:Gallium Isotopes; D005710:Gallium Radioisotopes; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008207:Lymphatic Metastasis; D008297:Male; D009842:Oligopeptides; D009942:Organometallic Compounds / Q000378:metabolism; D049268:Positron-Emission Tomography; D017430:Prostate-Specific Antigen / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary*; D014057:Tomography, X-Ray Computed
chemical_list: D005709:Gallium Isotopes; D005710:Gallium Radioisotopes; D009842:Oligopeptides; D009942:Organometallic Compounds; C000718244:gallium 68 PSMA-11; D004492:Edetic Acid; D017430:Prostate-Specific Antigen