title: Positive effects of egg-derived phospholipids in patients with metabolic syndrome.
abstract: OBJECTIVE
  Patients with metabolic syndrome (MBS) have an increased risk of all-cause mortality, especially from cardiovascular disease. Egg phospholipids (PL) have been shown to exert a positive impact on cholesterol metabolism and inflammation; eggs are an important source of PL. Our study examined potential effects of egg-yolk-derived PL in non-diabetic patients with MBS.
  
  
  METHODS
  The study group consisted of 40 patients with MBS diagnosed according to IDF criteria and divided into an experimental group receiving the PL preparation (n-6: n-3 fatty acids ratio: 1.79) and the comparison group receiving an olive oil preparation, for one month (2012/2013year). The studied dosage was 45ml (15ml 3 times per day). It was a randomized, double blinded study.
  
  
  RESULTS
  The waist to hip ratio, GGTP levels, plasma platelet concentrations and flow mediated vasodilation of brachial artery (FMD) significantly improved in the experimental group. A significant decrease in daytime ABPM blood pressure was noticed in both groups.
  
  
  CONCLUSIONS
  A phospholipid-enriched diet caused a significant improvement of endothelial vasodilatory function and a significant decrease in waist to hip ratio. A significant decrease in daytime systolic blood pressure were observed in both the phospholipid-enriched and oil-olive group.
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland; Division of Angiology, Wroclaw Medical University, Wroclaw, Poland. Electronic address: cathcor@poczta.onet.pl.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Skórkowska-Telichowska
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Kosińska
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
authors.forename: Monika
authors.initials: M
authors.lastname: Chwojnicka
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
authors.forename: Dominika
authors.initials: D
authors.lastname: Tuchendler
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Tabin
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland.
authors.forename: Renata
authors.initials: R
authors.lastname: Tuchendler
authors.affiliation: Department of Animal Products Technology and Quality Management, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Bobak
authors.affiliation: Department of Animal Products Technology and Quality Management, Wroclaw University of Environmental and Life Sciences, Wroclaw, Poland.
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Trziszka
authors.affiliation: Department of Internal Medicine, 4th Military Hospital, Wroclaw, Poland; Division of Angiology, Wroclaw Medical University, Wroclaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Szuba
mesh_terms: D000818:Animals; D002645:Chickens; D003710:Demography; D004531:Eggs; D005227:Fatty Acids / Q000032:analysis; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000188:drug therapy*; D008875:Middle Aged; D000069463:Olive Oil / Q000737:chemistry; D010743:Phospholipids / Q000627:therapeutic use*
chemical_list: D005227:Fatty Acids; D000069463:Olive Oil; D010743:Phospholipids
keywords: Civilization diseases; Dietary pattern; Flow mediated dilatation; Nutrition; Olive oil