title: Effects of differences in age and body height on normal values of central motor conduction time determined by F-waves.
abstract: To investigate the effect on central motor conduction time (CMCT) based on the relationship between age and height in normal subjects.
  
  
  
  Retrospective study.
  
  
  
  One hundred and ninety nine normal subjects (107 men and 92 women; mean age 39.0 ± 16.4 years; mean height 164.5 ± 8.8 cm) participated in the study. The approximate ages of subjects were as follows: 82 (20-29 years old), 32 (30-39 years old), 32 (40-49 years old), 28 (50-59 years old), and 25 (≧60 years old). The heights of 9, 49, 79, 53, and 9 subjects were <150 cm, 150-160 cm, 160-170 cm, 170-180 cm, and >180 cm, respectively. CMCT- abductor digiti minimi (ADM) and abductor hallucis (AH) were calculated by subtracting the peripheral motor conduction time (PMCT) from the onset latency of motor evoked potentials (MEPs) evoked by transcranial magnetic stimulation. PMCT was calculated from the latencies of the compound muscle action potentials (CMAPs) and F-waves as follows: (latency of CMAPs + latency of F-waves -1)/2.
  
  
  
  CMCT-ADM and CMCT-AH.
  
  
  
  The normative values were 5.2 ± 0.8 ms and 11.8 ± 1.3 ms for CMCT-ADM and CMCT-AH, respectively. CMCT-ADM was not significantly correlated with age (P = 0.196) and body height (P = 0.158). CMCT-AH had significantly positive, linear correlations with age and body height (CMCT-AH = 0.014 × age + 10.971, P = 0.011, R = 0.179 and CMCT-AH = 0.026 × body height + 7.158, P = 0.010, R = 0.182).
  
  
  
  We suggest normative values of 3.2-7.2 ms in CMCT-ADM for subjects exerting slight effort on ADM regardless age and body height. CMCT-AH had significantly positive, linear correlations with age and body height.
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Yasuaki
authors.initials: Y
authors.lastname: Imajo
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Kanchiku
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Suzuki
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Yoshida
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Funaba
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Nishida
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Fujimoto
authors.affiliation: a Department of Orthopaedic Surgery , Yamaguchi University Graduate School of Medicine Yamaguchi , Japan.
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Taguchi
mesh_terms: D000328:Adult; D000367:Age Factors; D001827:Body Height; D002490:Central Nervous System / Q000254:growth & development / Q000502:physiology*; D019054:Evoked Potentials, Motor; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000254:growth & development / Q000502:physiology; D011930:Reaction Time; D050781:Transcranial Magnetic Stimulation
keywords: Age; Body height; Central motor conduction time; F-wave; Normative values
references.citation: Clin Neurophysiol. 2013 Jun;124(6):1055-67
references.pmid: 23485367
references.citation: Clin Neurophysiol. 2006 Jul;117(7):1467-73
references.pmid: 16753333
references.citation: Muscle Nerve. 1998 Sep;21(9):1220-3
references.pmid: 9703453
references.citation: Spine (Phila Pa 1976). 1997 Mar 15;22(6):636-40
references.pmid: 9089936
references.citation: J Bone Joint Surg Am. 1990 Sep;72(8):1178-84
references.pmid: 2398088
references.citation: Electroencephalogr Clin Neurophysiol. 1991 Jun;81(3):195-201
references.pmid: 1710968
references.citation: Eur Spine J. 2011 Feb;20(2):240-6
references.pmid: 21197553
references.citation: Econ Hum Biol. 2007 Jul;5(2):340-9
references.pmid: 17412655
references.citation: J Neurol Neurosurg Psychiatry. 1999 Apr;66(4):456-64
references.pmid: 10201416
references.citation: Lancet. 1986 Jun 7;1(8493):1325-6
references.pmid: 2872449
references.citation: Pediatr Res. 2013 Mar;73(3):371-7
references.pmid: 23222908
references.citation: Neurology. 1979 Jan;29(1):38-44
references.pmid: 570675
references.citation: J Neurol Sci. 1992 Oct;112(1-2):113-25
references.pmid: 1469421
references.citation: Clin Neurophysiol. 2006 Mar;117(3):623-7
references.pmid: 16442342
references.citation: Neurology. 1987 Mar;37(3):529-32
references.pmid: 3822153
references.citation: Muscle Nerve. 1990 Nov;13(11):995-1011
references.pmid: 2233862
references.citation: Acta Neuropathol. 1994;88(2):137-42
references.pmid: 7985494
references.citation: Muscle Nerve. 1990 Dec;13(12):1125-32
references.pmid: 2266986
references.citation: Neurosurg Focus. 2013 Jul;35(1):E10
references.pmid: 23815246
references.citation: J Neurol Neurosurg Psychiatry. 1966 Feb;29(1):40-4
references.pmid: 5910577
references.citation: Electroencephalogr Clin Neurophysiol. 1994 Aug;91(2):79-92
references.pmid: 7519144
references.citation: Spine (Phila Pa 1976). 2015 Feb 1;40(3):E161-7
references.pmid: 25384053
references.citation: J Orthop Sci. 2015 Jan;20(1):38-54
references.pmid: 25477013
references.citation: Clin Neurophysiol. 2001 Jun;112(6):1035-40
references.pmid: 11377262
references.citation: Spine (Phila Pa 1976). 2010 Dec 15;35(26):E1593-8
references.pmid: 21116217
references.citation: Intern Med. 1992 Sep;31(9):1084-7
references.pmid: 1421713
references.citation: Muscle Nerve. 2012 Dec;46(6):932-6
references.pmid: 23018984