title: Effect of elasticity on wall shear stress inside cerebral aneurysm at anterior cerebral artery.
abstract: BACKGROUND
  Many numerical studies have been published with respect to about flow structures around cerebral aneurysm assuming to be rigid. Furthermore, there is little experimental research concerning aneurysm with elastic wall. Wall shear stress in elastic wall comparing with rigid wall should be clarified in experimental approach and verified in CFD.
  
  
  OBJECTIVE
  We have experimentally realized elastic aneurysm model accompanying with wall deformation. Wall shear stress was examined for both rigid and elastic aneurysm models in pulsatile flow.
  
  
  METHODS
  Effect of elasticity on wall shear stress inside aneurysm induced at the apex of anterior cerebral artery was experimentally examined by particle image velocimetry in vitro. In order to adjust the wall deformation, the pressure adjustment chamber was specially equipped outside the aneurysm wall.
  
  
  RESULTS
  Effect of elasticity on wall shear stress was noticed on the comparison with that of rigidity. Wall elasticity reduced the peak magnitude, the spatial and temporal averaged wall shear stress comparing with those of wall rigidity experimentally. These reductions were endorsed by fluid-structure interaction simulation.
  
  
  CONCLUSIONS
  Elastic wall comparing with rigid wall would reduce the peak magnitude, the spatial and temporal averaged wall shear stress acting on vascular wall.
authors.affiliation: Graduate School of Engineering, Chiba University, Chiba, Japan.
authors.forename: Lijian
authors.initials: L
authors.lastname: Xu
authors.affiliation: Graduate School of Engineering, Chiba University, Chiba, Japan.
authors.forename: Michiko
authors.initials: M
authors.lastname: Sugawara
authors.affiliation: Graduate School of Engineering, Chiba University, Chiba, Japan.
authors.forename: Gaku
authors.initials: G
authors.lastname: Tanaka
authors.affiliation: Institute of Fluid Science, Tohoku University, Miyagi, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Ohta
authors.affiliation: Graduate School of Engineering, Chiba University, Chiba, Japan.
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
authors.affiliation: Graduate School of Engineering, Chiba University, Chiba, Japan.
authors.forename: Ryuhei
authors.initials: R
authors.lastname: Yamaguchi
mesh_terms: D020771:Anterior Cerebral Artery / Q000503:physiopathology*; D001783:Blood Flow Velocity; D003198:Computer Simulation; D004548:Elasticity / Q000502:physiology*; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology*; D008955:Models, Cardiovascular; D013314:Stress, Mechanical
keywords: CFD; Cerebral aneurysm; PIV; elasticity; hemodynamics; wall shear stress