title: [MODERN APPROACHES TO THE DIAGNOSIS AND TREATMENT OF CHEMOTHERAPY TOXICITY IN PATIENTS WITH BREAST CANCER].
abstract: The use of modern chemotherapy (CT) allowed to achieve significant progress in the treatment of many malignant tumors that were previously considered fatal. Improving the efficiency of the treatment was achieved by the intensification of chemotherapy. However, intensification of chemotherapy regimes provoked increase in the number of side effects of anticancer therapy,which often lead to a decrease in the intensity of the selected mode, the additional financial costs of treating the complications and the formation of the negative attitude of the patient to treatment. Thus, the side effects of chemotherapy are the actual problem of modern oncology. The purpose of this literature review was to investigate the frequency, symptoms and ways to prevent and treat various types of toxicity of chemotherapy.
authors.forename: L A
authors.initials: LA
authors.lastname: Syvak
authors.forename: H O
authors.initials: HO
authors.lastname: Hubareva
authors.forename: K S
authors.initials: KS
authors.lastname: Filonenko
authors.forename: N M
authors.initials: NM
authors.lastname: Majdanevych
authors.forename: O M
authors.initials: OM
authors.lastname: Aleksyk
authors.forename: S A
authors.initials: SA
authors.lastname: Lyalkin
authors.forename: M J
authors.initials: MJ
authors.lastname: Klimanov
authors.forename: A V
authors.initials: AV
authors.lastname: Askolskyi
authors.forename: N V
authors.initials: NV
authors.lastname: Kasap
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols; D001943:Breast Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D005260:Female; D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D009503:Neutropenia / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism; D020011:Protective Agents / Q000627:therapeutic use*; D011985:Receptors, Serotonin / Q000378:metabolism; D012702:Serotonin Antagonists / Q000627:therapeutic use; D014839:Vomiting / Q000139:chemically induced / Q000175:diagnosis / Q000188:drug therapy* / Q000378:metabolism
chemical_list: D000970:Antineoplastic Agents; D020011:Protective Agents; D011985:Receptors, Serotonin; D012702:Serotonin Antagonists