title: Novel Insights Into the Mechanisms Regulating Pro-Atrial Natriuretic Peptide Cleavage in the Heart and Blood Pressure Regulation: Proprotein Convertase Subtilisin/Kexin 6 Is the Corin Activating Enzyme.
authors.affiliation: From the Department of Clinical and Molecular Medicine, School of Medicine and Psychology, University Sapienza of Rome, Ospedale S. Andrea, Rome; and IRCCS Neuromed, Angio-Cardio-Neurology Department, Pozzilli, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Volpe
authors.affiliation: From the Department of Clinical and Molecular Medicine, School of Medicine and Psychology, University Sapienza of Rome, Ospedale S. Andrea, Rome; and IRCCS Neuromed, Angio-Cardio-Neurology Department, Pozzilli, Italy.
authors.forename: Speranza
authors.initials: S
authors.lastname: Rubattu
mesh_terms: D000818:Animals; D009320:Atrial Natriuretic Factor / Q000378:metabolism*; D001794:Blood Pressure; D002460:Cell Line; D004789:Enzyme Activation; D006801:Humans; D006973:Hypertension / Q000201:enzymology* / Q000235:genetics / Q000503:physiopathology; D051379:Mice; D018345:Mice, Knockout; D009206:Myocardium / Q000201:enzymology*; D043484:Proprotein Convertases / Q000172:deficiency / Q000235:genetics / Q000378:metabolism*; D011498:Protein Precursors / Q000378:metabolism*; D012697:Serine Endopeptidases / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction; D014162:Transfection
chemical_list: D011498:Protein Precursors; D009320:Atrial Natriuretic Factor; C119812:CORIN protein, human; C485617:Corin protein, mouse; C080654:PCSK6 protein, human; C513086:Pcsk6 protein, mouse; D043484:Proprotein Convertases; D012697:Serine Endopeptidases