title: Photo-activated CO-releasing molecules (PhotoCORMs) of robust sawhorse scaffolds [μ(2)-OOCR(1), η(1)-NH2CHR(2)(C = O] OCH3, Ru(I)2CO4].
abstract: A class of sawhorse-type ruthenium(i) complexes featuring a stable CORM sphere with diverse carboxylic and amino acid derivatives were synthesized and validated as lead structures for photo-activated CO-releasing molecules (PhotoCORMs). The CO release of these CORMs was triggered by 365 nm UV irradiation. Cell viability studies indicated that 3a and 3f were non-toxic both in the dark and in UV light, making them excellent lead structures for therapeutic CORMs.
authors.affiliation: Key Laboratory of Applied Surface and Colloid Chemistry, MOE, School of Chemistry and Chemical Engineering Shaanxi Normal University, Xi'an 710062, China. zwq@snnu.edu.cn.
authors.forename: Shuhong
authors.initials: S
authors.lastname: Yang
authors.forename: Mengjiao
authors.initials: M
authors.lastname: Chen
authors.forename: Lingling
authors.initials: L
authors.lastname: Zhou
authors.forename: Guofang
authors.initials: G
authors.lastname: Zhang
authors.forename: Ziwei
authors.initials: Z
authors.lastname: Gao
authors.forename: Weiqiang
authors.initials: W
authors.lastname: Zhang