title: Myxoid Neoplasms.
abstract: Myxoid tumors of soft tissue constitute a heterogeneous group of neoplasms characterized by the presence of a myxoid stromal matrix, which appears on H&E as an amorphous material and may be confused with edema. Superficial myxoid lesions in general are benign and deep ones are malignant. Grossly, they have a variable gelatinous quality and overlapping histologic features that may present diagnostic difficulties for pathologists. Most are sporadic neoplasms, with only a small percentage arising in patients with hereditary disorders. Discussed are key features of classic myxoid lesions, histologic features, characteristic clinical presentations, immunohistochemical patterns, cytogenetic analysis, and differential diagnosis.
authors.affiliation: Department of Pathology, St John Hospital and Medical Center, 22101 Moross Road, CCB-SB, Detroit, MI 48236, USA.
authors.forename: Muhammad I
authors.initials: MI
authors.lastname: Zulfiqar
authors.affiliation: Department of Pathology, St John Hospital and Medical Center, 22101 Moross Road, CCB-SB, Detroit, MI 48236, USA.
authors.forename: Umer N
authors.initials: UN
authors.lastname: Sheikh
authors.affiliation: Department of Pathology, The Johns Hopkins Medical Institutions, 401 North Broadway, Weinberg 2242, Baltimore, MD 21231-2410, USA.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Montgomery