title: [Synthetic evaluation of precancerous lesions and early esophageal cancers after endoscopic submucosal dissection].
abstract: OBJECTIVE
  To evaluate the safety and prognosis for patients with early esophageal cancer and precancerous lesions after endoscopic submucosal dissection (ESD).
  
  
  METHODS
  A total of 89 patients were admitted to the Department of internal medicine in the First People's Hospital of Anqing from August 2008 to August 2011. All patients were treated with ESD at the early stage of esophageal cancer and precancerous lesions. The patients' laboratory data and relevant medical history were collected. The postoperative complications and long-term effects of ESD were analyzed.
  
  
  RESULTS
  Eighty-nine patients were followed up with 100% response rate. Among 89 cases, 16 were early esophageal cancer, 38 were high-grade esophageal neoplasia and 35 were low-grade esophageal neoplasia. The one-time whole piece resection rate, complete resection rate and curative resection rate was 93.3% (84/89), 92.1% (82/89) and 92.1% (82/89), respectively. Two cases suffered intraoperative perforation with a rate of 2.2% and these 2 patients performed the intraoperative endoscopic repair; one case suffered the postoperative delayed bleeding with a rate of 1.1% and the patient underwent the conservative treatment; three cases suffered the esophageal stenosis with a rate of 3.4%. All patients were followed-up for 10-58 (36.3±21.2) months. In this period, one case recurred after ESD for 3 years with a rate of 1.1%; two cases were dead. The three-year survival rate was 97.8%.
  
  
  CONCLUSIONS
  The early esophageal cancer and precancerous lesions can be treated with ESD. The method is safe and the prognosis is good.
authors.affiliation: Department of Gastroenterology, The First People's Hospital of Anqing, Anqing Anhui 246003, China.
authors.forename: Ansheng
authors.initials: A
authors.lastname: Ling
authors.affiliation: Department of Gastroenterology, The First People's Hospital of Anqing, Anqing Anhui 246003, China.
authors.forename: Fanglai
authors.initials: F
authors.lastname: Zhu
authors.affiliation: Department of Gastroenterology, The First People's Hospital of Anqing, Anqing Anhui 246003, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Wu
authors.affiliation: Department of Gastroenterology, The First People's Hospital of Anqing, Anqing Anhui 246003, China.
authors.forename: Chongwen
authors.initials: C
authors.lastname: Fang
authors.affiliation: Department of Gastroenterology, The First People's Hospital of Anqing, Anqing Anhui 246003, China.
authors.forename: Fuliu
authors.initials: F
authors.lastname: Cao
mesh_terms: D004210:Dissection; D004724:Endoscopy / Q000009:adverse effects*; D004938:Esophageal Neoplasms / Q000601:surgery*; D004939:Esophageal Perforation; D004940:Esophageal Stenosis; D006801:Humans; D011183:Postoperative Complications; D019106:Postoperative Hemorrhage; D011379:Prognosis