title: Serum Basic Fibroblastic Growth Factor Levels in Children with Infantile Hemangioma.
abstract: OBJECTIVE
  To determine serum levels of basic fibroblastic growth factor (b-FGF) in hemangioma patients under 2 y of age.
  
  
  METHODS
  The study group consisted of 43 children with infantile hemangioma and b-FGF levels were analyzed using ELISA.
  
  
  RESULTS
  The serum b-FGF levels were higher in hemangioma patients than in healthy control individuals (p 0.01). There were no differences between the lesion size, number of lesions, patient age and serum b-FGF levels.
  
  
  CONCLUSIONS
  Thus, b-FGF is an important growth factor that plays a central role in hemangioma, but determining b-FGF serum levels was not helpful in distinguishing between patients who require treatment and those who do not.
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey. g_oktay4910@yahoo.com.
authors.forename: Hikmet Gulsah
authors.initials: HG
authors.lastname: Tanyildiz
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Emel Cabi
authors.initials: EC
authors.lastname: Unal
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Hafize
authors.initials: H
authors.lastname: Gokce
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Gulsan
authors.initials: G
authors.lastname: Yavuz
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Nurdan
authors.initials: N
authors.lastname: Tacyildiz
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Handan
authors.initials: H
authors.lastname: Dincaslan
authors.affiliation: Division of Pediatric Hematology/Oncology, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Ceyda
authors.initials: C
authors.lastname: Gurman
authors.affiliation: Division of Biostatistics, Cebeci Medical Faculty Ankara, Ankara University, Ankara, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Biyikli
mesh_terms: D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D016222:Fibroblast Growth Factor 2 / Q000097:blood*; D018324:Hemangioma, Capillary / Q000175:diagnosis* / Q000628:therapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D010347:Patient Care Planning
chemical_list: D016222:Fibroblast Growth Factor 2
keywords: Children; Hemangioma; Serum basic fibroblastic growth factor
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