title: Quantification of Right and Left Ventricular Function in Cardiac MR Imaging: Comparison of Semiautomatic and Manual Segmentation Algorithms.
abstract: The purpose of this study was to evaluate the performance of a semiautomatic segmentation method for the anatomical and functional assessment of both ventricles from cardiac cine magnetic resonance (MR) examinations, reducing user interaction to a "mouse-click". Fifty-two patients with cardiovascular diseases were examined using a 1.5-T MR imaging unit. Several parameters of both ventricles, such as end-diastolic volume (EDV), end-systolic volume (ESV) and ejection fraction (EF), were quantified by an experienced operator using the conventional method based on manually-defined contours, as the standard of reference; and a novel semiautomatic segmentation method based on edge detection, iterative thresholding and region growing techniques, for evaluation purposes. No statistically significant differences were found between the two measurement values obtained for each parameter (p > 0.05). Correlation to estimate right ventricular function was good (r > 0.8) and turned out to be excellent (r > 0.9) for the left ventricle (LV). Bland-Altman plots revealed acceptable limits of agreement between the two methods (95%). Our study findings indicate that the proposed technique allows a fast and accurate assessment of both ventricles. However, further improvements are needed to equal results achieved for the right ventricle (RV) using the conventional methodology.
authors.affiliation: Department of Radiology, University Hospital Complex of Santiago (CHUS), Santiago de Compostela, A Coruña 15706, Spain. miguel.souto@usc.es.|Department of Radiology, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña 15706, Spain. miguel.souto@usc.es.
authors.forename: Miguel
authors.initials: M
authors.lastname: Souto
authors.affiliation: Department of Radiology, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña 15706, Spain. lambertraul.masip@usc.es.
authors.forename: Lambert Raul
authors.initials: LR
authors.lastname: Masip
authors.affiliation: Department of Radiology, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña 15706, Spain. ixem.couto@gmail.com.
authors.forename: Miguel
authors.initials: M
authors.lastname: Couto
authors.affiliation: Department of Radiology, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña 15706, Spain.
authors.forename: Jorge Juan
authors.initials: JJ
authors.lastname: Suárez-Cuenca
authors.affiliation: Department of Cardiology, University Hospital Complex of Santiago (CHUS), Santiago de Compostela, A Coruña 15706, Spain. mariaamparo.martinez.monzonis@sergas.es.
authors.forename: Amparo
authors.initials: A
authors.lastname: Martínez
authors.affiliation: Department of Electronics and Computer Science, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña 15706, Spain. pablo.tahoces@usc.es.
authors.forename: Pablo G
authors.initials: PG
authors.lastname: Tahoces
authors.affiliation: Department of Radiology, University Hospital Complex of Santiago (CHUS), Santiago de Compostela, A Coruña 15706, Spain. jorgejuan.suarez@usc.es.|Department of Radiology, University of Santiago de Compostela (USC), Santiago de Compostela, A Coruña 15706, Spain. jorgejuan.suarez@usc.es.
authors.forename: Jose Martin
authors.initials: JM
authors.lastname: Carreira
authors.affiliation: Department of Radiology, Hôpital Nord/Centre Hospital Universitaire (CHU) Saint-Etienne, Université de Lyon, Saint-Etienne 42000, France. croisille@creatis.univ-lyon1.fr.
authors.forename: Pierre
authors.initials: P
authors.lastname: Croisille
keywords: cardiac cine magnetic resonance imaging (MRI); ejection fraction (EF); left ventricular function; right ventricular function; segmentation
references.citation: Eur Radiol. 2010 Dec;20(12):2844-52
references.pmid: 20640427
references.citation: Magn Reson Imaging. 1994;12(4):589-98
references.pmid: 8057763
references.citation: J Magn Reson Imaging. 2005 Feb;21(2):140-8
references.pmid: 15666401
references.citation: Int J Cardiovasc Imaging. 2008 Feb;24(2):185-91
references.pmid: 17597423
references.citation: Eur Heart J. 2006 Dec;27(23):2879-88
references.pmid: 17088316
references.citation: Lancet. 1986 Feb 8;1(8476):307-10
references.pmid: 2868172
references.citation: Int J Cardiovasc Imaging. 2011 Apr;27(4):563-9
references.pmid: 20886372
references.citation: J Cardiovasc Magn Reson. 2000;2(4):271-8
references.pmid: 11545126
references.citation: J Magn Reson Imaging. 2005 Jul;22(1):59-66
references.pmid: 15971180
references.citation: Med Image Anal. 2011 Apr;15(2):169-84
references.pmid: 21216179
references.citation: J Cardiovasc Magn Reson. 2011 Jan 20;13:9
references.pmid: 21251297
references.citation: J Cardiovasc Magn Reson. 2011 Aug 11;13:40
references.pmid: 21834992
references.citation: Heart. 1997 Aug;78(2):127-30
references.pmid: 9326984
references.citation: Radiologia. 2008 Jan-Feb;50(1):67-74
references.pmid: 18275792
references.citation: Eur Radiol. 2005 Sep;15(9):1987-93
references.pmid: 15776241
references.citation: J Am Coll Cardiol. 2006 Oct 3;48(7):1475-97
references.pmid: 17010819
references.citation: J Magn Reson Imaging. 2008 Apr;27(4):785-92
references.pmid: 18302202
references.citation: Int J Cardiovasc Imaging. 2009 Mar;25(3):263-70
references.pmid: 19048388
references.citation: J Magn Reson Imaging. 2008 Sep;28(3):626-36
references.pmid: 18777544
references.citation: Heart. 2006 Apr;92 Suppl 1:i2-13
references.pmid: 16543598
references.citation: Magn Reson Med. 2007 Mar;57(3):600-5
references.pmid: 17326180
references.citation: Eur Radiol. 2006 May;16(5):1117-23
references.pmid: 16372162
references.citation: J Cardiovasc Magn Reson. 2004;6(3):609-17
references.pmid: 15347125
references.citation: J Magn Reson Imaging. 2003 Mar;17(3):323-9
references.pmid: 12594722
references.citation: J Cardiovasc Magn Reson. 2005;7(5):775-82
references.pmid: 16353438
references.citation: Eur Radiol. 2008 May;18(5):939-46
references.pmid: 18292999
references.citation: Eur Radiol. 2010 Jun;20(6):1344-55
references.pmid: 20013275
references.citation: Eur Radiol. 2010 Oct;20(10):2341-7
references.pmid: 20532781