title: Impact of an Information Leaflet on Knowledge of Hepatocellular Carcinoma and Hepatitis B among Chinese Youth.
abstract: BACKGROUND
  To assess the effect of an information leaflet on the level of Chinese youth's knowledge about hepatitis B and hepatocellular carcinoma (HCC), the most common type of primary liver cancer (PLC).
  
  
  METHODS
  A total of 500 students, from two universities in the Chaoshan area of China, were randomly divided into an intervention group of 280 participants and a control group of 220. Baseline knowledge of HCC and hepatitis B was evaluated by questionnaire interview. Subsequently, only the intervention group was given an information leaflet of HCC and hepatitis B. Three months later, the two groups were contacted for a second interview. Changes in knowledge from baseline of HCC and hepatitis B were compared between the two groups.
  
  
  RESULTS
  There was no statistically significant difference in mean PRE-questionnaire scores between the intervention and control groups. However, the mean POST-questionnaire score was significantly higher in the intervention group after the intervention. The leaflet had the greatest effect on the participants' questionnaire score, and raised their level of knowledge about HCC and hepatitis B.
  
  
  CONCLUSIONS
  The information leaflet intervention is significantly effective in improving the knowledge of HCC and hepatitis B among the youth.
authors.affiliation: Shantou University Medical College, Shantou, Guangdong, China E-mail : walch_jay@126.com.
authors.forename: Jun-Jie
authors.initials: JJ
authors.lastname: Ouyang
authors.forename: Wen-Jing
authors.initials: WJ
authors.lastname: He
authors.forename: Kai-Xin
authors.initials: KX
authors.lastname: Zheng
authors.forename: Geng-Zhen
authors.initials: GZ
authors.lastname: Chen
mesh_terms: D000293:Adolescent; D000328:Adult; D044466:Asian People; D006528:Carcinoma, Hepatocellular / Q000517:prevention & control*; D016022:Case-Control Studies; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006509:Hepatitis B / Q000517:prevention & control*; D006801:Humans; D008113:Liver Neoplasms / Q000517:prevention & control*; D008297:Male; D012307:Risk Factors; D013334:Students; D011795:Surveys and Questionnaires; D014495:Universities; D055815:Young Adult