title: Electrophysiological Indicators of the Age-Related Deterioration in the Sensitivity to Auditory Duration Deviance.
abstract: The present study investigates age-related changes in duration discrimination in millisecond time domain. We tested young (N = 20, mean age = 24.5, SD = 2.97) and elderly (N = 20, mean age = 65.2, SD = 2.94) subjects using the mismatch negativity (MMN) paradigm. White-noise bursts of two different durations (50 and 10 ms) were presented in two oddball blocks. In one block (Increment Condition), the repetitive sequence of 10 ms standards was interspersed by occasional 50 ms deviants. In the Decrement Condition, the roles of the two stimuli were reversed. We analyzed the P1-N1 complex, MMN and P3a and found the effect of age for all these components. Moreover, the impact of stimulus presentation condition (increment/decrement) was observed for MMN and P3a. Our results confirmed the previous evidence for deteriorated duration discrimination in elderly people. Additionally, we found that this effect may be influenced by procedural factors.
authors.affiliation: Laboratory of Neuropsychology, Nencki Institute of Experimental BiologyWarsaw, Poland; University of Social Sciences and HumanitiesWarsaw, Poland.
authors.forename: Kamila
authors.initials: K
authors.lastname: Nowak
authors.affiliation: Laboratory of Neuropsychology, Nencki Institute of Experimental Biology Warsaw, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Oron
authors.affiliation: Laboratory of Neuropsychology, Nencki Institute of Experimental BiologyWarsaw, Poland; University of Social Sciences and HumanitiesWarsaw, Poland.
authors.forename: Aneta
authors.initials: A
authors.lastname: Szymaszek
authors.affiliation: Center of Functionally Integrative Neuroscience (CFIN), Aarhus University/Aarhus University HospitalAarhus, Denmark; Cognitive Brain Research Unit, Cognitive Science, Institute of Behavioural Sciences, University of HelsinkiHelsinki, Finland.
authors.forename: Miika
authors.initials: M
authors.lastname: Leminen
authors.affiliation: Center of Functionally Integrative Neuroscience (CFIN), Aarhus University/Aarhus University HospitalAarhus, Denmark; Cognitive Brain Research Unit, Cognitive Science, Institute of Behavioural Sciences, University of HelsinkiHelsinki, Finland; Department of Psychology, University of TartuTartu, Estonia.
authors.forename: Risto
authors.initials: R
authors.lastname: Näätänen
authors.affiliation: Laboratory of Neuropsychology, Nencki Institute of Experimental BiologyWarsaw, Poland; University of Social Sciences and HumanitiesWarsaw, Poland.
authors.forename: Elzbieta
authors.initials: E
authors.lastname: Szelag
keywords: P3a; aging; duration discrimination; mismatch negativity (MMN); temporal information processing
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