title: [Physical activity and cancer: Update and literature review].
abstract: Physical activity is a key determinant of public health and contributes to decreasing the prevalence of many diseases. Cancer is the leading cause of death worldwide. Physical activity, accessible to the entire population, could prevent up to 25% of cancers, in addition to improving survival rates and quality of life in cancer patients. Physical activity acts via various mechanisms to slow or decrease tumor growth, including the production and bioavailability of sex hormones, insulin resistance and insulin secretion, and inflammation. In primary prevention, physical activity reduces breast cancer risk by 15-20% and colorectal cancer risk by 24%. All-cause mortality is reduced by 33% in cancer survivors who exercise. Health-related quality of life, fatigue and depression are enhanced by the practice of physical activity in cancer patients. In the general population, the global recommendations on physical activity for health, published by the World Health Organisation, are suggested as a means of primary prevention of cancer. In cancer patients, an adapted physical activity routine is promoted from the very beginning of patient care to decrease fatigue as well as improve tolerance and benefits of treatments.
authors.affiliation: Département de médecine interne, centre hospitalier universitaire de Sherbrooke, 3001, 12(e) avenue Nord, J1H 5N4 Sherbrooke, QC, Canada. Electronic address: alexandra.desnoyers@usherbrooke.ca.
authors.forename: A
authors.initials: A
authors.lastname: Desnoyers
authors.affiliation: Faculté des sciences de l'activité physique, université de Sherbrooke, 2500, boulevard de l'Université, J1K 2A1 Sherbrooke, QC, Canada.
authors.forename: E
authors.initials: E
authors.lastname: Riesco
authors.affiliation: Département de gériatrie, centre hospitalier universitaire de Sherbrooke, 3001, 12(e) avenue Nord, J1H 5N4 Sherbrooke, QC, Canada; Centre de recherche sur le vieillissement, centre hospitalier universitaire de Sherbrooke, 3001, 12(e) avenue Nord, J1H 5N4 Sherbrooke, QC, Canada.
authors.forename: T
authors.initials: T
authors.lastname: Fülöp
authors.affiliation: Département d'hémato-oncologie, centre hospitalier universitaire de Sherbrooke, 3001, 12(e) avenue Nord, J1H 5N4 Sherbrooke, QC, Canada; Centre de recherche, centre hospitalier universitaire de Sherbrooke, 3001, 12(e) avenue Nord, J1H 5N4 Sherbrooke, QC, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Pavic
mesh_terms: D015444:Exercise / Q000502:physiology*; D005221:Fatigue; D006304:Health Status; D006801:Humans; D009369:Neoplasms / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D057185:Sedentary Behavior; D017741:Survivors
keywords: Activité physique; Cancer; Exercise; Fatigue; Neoplasms; Prevention; Prévention; Quality of life; Qualité de vie