title: [Waist circumference as a marker for screening nonalcoholic fatty liver disease in obese adolescents].
abstract: OBJECTIVE
  To assess the relationship between the degree of waist circumference (WC) and nonalcoholic fatty liver disease (NAFLD) in obese adolescents of both genders, analyzed according to quartiles of WC.
  
  
  METHODS
  Cross-sectional study that involved 247 obese adolescents aged 12-19 years. Mean values of the nutritional parameters and serum analyses were compared with the groups using the independent t-test. Pearson correlation coefficient was used to determine the relationship of the parameters studied. Chi-square test for trend was used to determine the relationship between the prevalence of the NAFLD and WC quartile by gender.
  
  
  RESULTS
  NAFLD were presented in 60% of the study participants. Obese adolescents in the 3rd and 4th quartiles of WC presented higher prevalence of NAFLD when compared with that in the 1st quartile in both genders. The NAFLD patients had significantly higher values for body weight, BMI (body mass index), BAZ-score (BMI-for-age z-scores), total fat (% and kg), WC, visceral fat, insulin, insulin resistance index (HOMA-IR), aspartate aminotransferase and alanine aminotransferase, when compared with non-NAFLD obese adolescents.
  
  
  CONCLUSIONS
  The results presented here suggest that an increase in WC can reliably predict the risk of NAFLD in obese adolescents. This is a low cost and easy-to-use tool that can help in screening in adolescents.
authors.affiliation: Universidade Federal de Alagoas (Ufal), Maceió, AL, Brasil. Electronic address: anagrotticlemente@gmail.com.
authors.forename: Ana Paula Grotti
authors.initials: AP
authors.lastname: Clemente
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Bárbara Dal Molin
authors.initials: BD
authors.lastname: Netto
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Joana Pereira
authors.initials: JP
authors.lastname: de Carvalho-Ferreira
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Raquel Munhoz
authors.initials: RM
authors.lastname: da Silveira Campos
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Aline
authors.initials: A
authors.lastname: de Piano Ganen
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Lian
authors.initials: L
authors.lastname: Tock
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Marco Túlio
authors.initials: MT
authors.lastname: de Mello
authors.affiliation: Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-Unifesp), São Paulo, SP, Brasil.
authors.forename: Ana Raimunda
authors.initials: AR
authors.lastname: Dâmaso
mesh_terms: D000293:Adolescent; D000410:Alanine Transaminase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D006801:Humans; D007333:Insulin Resistance; D065626:Non-alcoholic Fatty Liver Disease / Q000097:blood / Q000175:diagnosis*; D009752:Nutritional Status; D063766:Pediatric Obesity / Q000097:blood / Q000150:complications*; D055105:Waist Circumference; D055815:Young Adult
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase
keywords: Abdominal fat; Adolescentes; Adolescents; Alanina aminotransferase; Alanine aminotransferase; Aspartate aminotransferase; Aspartato aminotransferase; Gordura abdominal
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