title: Giant solitary fibrous tumour of the pleura. Case report and review of the literature.
abstract: BACKGROUND
  Solitary fibrous tumours of the pleura (SFTP) are rare tumours. They are mostly benign. Only around 12% of them are malign ant. In the initial stage they are mostly asymptomatic and by growing they cause chest pain, irritating cough and dyspnoea on account of the pressure created on the surrounding structures. Rare giant tumours have compression symptoms on the mediastinal structures. The condition requires tiered diagnostic radiology. Preoperative biopsy is not successful in most cases. The therapy of choice is radical surgical tumour removal. Malignant or non-radically removed benign solitary fibrous tumours of the pleura additionally require neoadjuvant therapy.
  
  
  METHODS
  A 68-year old patient was hospitalized for giant solitary fibrous tumour of the pleura in the right pleural cavity. With its expansive growth the tumour caused the shift of the mediastinum by compressing the lower vena cava, right cardiac auricle as well as the intermediate and lower lobe bronchus. Due to cardiac inflow obstruction and right lung collapse, the patient's life was endangered with signs of cardio-respiratory failure. After preoperative diagnostic radiology, the tumour was surgically removed. Postoperatively, the patient's condition improved. No disease recurrence was diagnosed after a year.
  
  
  CONCLUSIONS
  Giant solitary fibrous tumour of the pleura may cause serious and life-threatening conditions by causing compression of the pleural cavity with its expansive growth. Early diagnosis of the condition enables less aggressive as well as video-assisted thoracic surgery in patients with significantly better state of health. Large tumour surgeries in cardio-respiratory affected patients are highly risk-associated procedures.
authors.affiliation: Department of Thoracic Surgery, Division of Surgery, University Medical Centre Maribor, Slovenia.
authors.forename: Anton
authors.initials: A
authors.lastname: Crnjac
authors.affiliation: Department of Thoracic Surgery, Division of Surgery, University Medical Centre Maribor, Slovenia.
authors.forename: Bojan
authors.initials: B
authors.lastname: Veingerl
authors.affiliation: Department of Thoracic Surgery, Division of Surgery, University Medical Centre Maribor, Slovenia.
authors.forename: Damjan
authors.initials: D
authors.lastname: Vidovic
authors.affiliation: Department of Pathology, University Medical Centre Maribor, Slovenia.
authors.forename: Rajko
authors.initials: R
authors.lastname: Kavalar
authors.affiliation: Department of Thoracic Surgery, Division of Surgery, University Medical Centre Maribor, Slovenia.
authors.forename: Aljaz
authors.initials: A
authors.lastname: Hojski
keywords: expansive growth; mediastinum shift; solitary fibrous tumour of the pleura; surgical treatment
references.citation: Eur J Cardiothorac Surg. 2012 Mar;41(3):587-97
references.pmid: 22345180
references.citation: Eur J Cardiothorac Surg. 2014 Jun;45(6):1108-10
references.pmid: 24078101
references.citation: Wien Klin Wochenschr. 2001;113 Suppl 3:18-20
references.pmid: 15503615
references.citation: Am J Surg Pathol. 1989 Aug;13(8):640-58
references.pmid: 2665534
references.citation: Thorac Cardiovasc Surg. 2008 Aug;56(5):287-90
references.pmid: 18615376
references.citation: Ann Thorac Surg. 2002 Jul;74(1):285-93
references.pmid: 12118790
references.citation: Eur J Cardiothorac Surg. 1998 Nov;14(5):453-9
references.pmid: 9860200
references.citation: AJR Am J Roentgenol. 1985 Feb;144(2):275-80
references.pmid: 3871270
references.citation: Am J Surg Pathol. 1994 Aug;18(8):814-20
references.pmid: 7518652
references.citation: Radiographics. 1992 Nov;12 (6):1191-201
references.pmid: 1439021
references.citation: J Comput Assist Tomogr. 1997 Jan-Feb;21(1):115-20
references.pmid: 9022782
references.citation: Histopathology. 1993 Mar;22(3):282-4
references.pmid: 8495961
references.citation: Clin Lung Cancer. 2005 Nov;7(3):197-201
references.pmid: 16354315
references.citation: J Cardiothorac Surg. 2011 Sep 29;6:122
references.pmid: 21958732
references.citation: Eur J Cardiothorac Surg. 2001 Feb;19(2):185-9
references.pmid: 11167110
references.citation: Virchows Arch. 2005 Jun;446(6):646-52
references.pmid: 15909170
references.citation: J Thorac Cardiovasc Surg. 2000 Jan;119(1):185-7
references.pmid: 10612786
references.citation: Radiol Oncol. 2010 Jun;44(2):92-6
references.pmid: 22933897
references.citation: Radiographics. 1998 Mar-Apr;18(2):523-5
references.pmid: 9536495
references.citation: J Cardiovasc Surg (Torino). 2000 Oct;41(5):781-4
references.pmid: 11149649
references.citation: Cancer Control. 2006 Oct;13(4):264-9
references.pmid: 17075563
references.citation: Radiol Oncol. 2012 Jun;46(2):136-44
references.pmid: 23077450
references.citation: AJR Am J Roentgenol. 2011 Mar;196(3):487-95
references.pmid: 21343490
references.citation: Ann Thorac Surg. 2005 Jan;79(1):303-7
references.pmid: 15620963
references.citation: Chest. 2000 Mar;117(3):897-900
references.pmid: 10713024
references.citation: J Laryngol Otol. 1993 Mar;107(3):252-6
references.pmid: 8509708
references.citation: Eur J Cardiothorac Surg. 1998 Aug;14 (2):211-3
references.pmid: 9755010
references.citation: Cancer. 2011 Nov 1;117(21):4939-47
references.pmid: 21480200
references.citation: AJR Am J Roentgenol. 2000 Sep;175(3):872; 875-6
references.pmid: 10954488
references.citation: Wien Klin Wochenschr. 2004;116 Suppl 2:28-32
references.pmid: 15506307
references.citation: Eur J Cardiothorac Surg. 2002 Jun;21(6):1087-93
references.pmid: 12048090
references.citation: Chest. 1997 Nov 5;112(5):1424-8
references.pmid: 9367487
references.citation: Curr Treat Options Oncol. 2000 Oct;1(4):293-8
references.pmid: 12057154