title: A photonic crystal hydrogel suspension array for the capture of blood cells from whole blood.
abstract: Diagnosing hematological disorders based on the separation and detection of cells in the patient's blood is a significant challenge. We have developed a novel barcode particle-based suspension array that can simultaneously capture and detect multiple types of blood cells. The barcode particles are polyacrylamide (PAAm) hydrogel inverse opal microcarriers with characteristic reflection peak codes that remain stable during cell capture on their surfaces. The hydrophilic PAAm hydrogel scaffolds of the barcode particles can entrap various plasma proteins to capture different cells in the blood, with little damage to captured cells.
authors.affiliation: State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing 210096, China. yjzhao@seu.edu.cn gu@seu.edu.cn.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.forename: Yunlang
authors.initials: Y
authors.lastname: Cai
authors.forename: Luoran
authors.initials: L
authors.lastname: Shang
authors.forename: Huan
authors.initials: H
authors.lastname: Wang
authors.forename: Yao
authors.initials: Y
authors.lastname: Cheng
authors.forename: Fei
authors.initials: F
authors.lastname: Rong
authors.forename: Zhongze
authors.initials: Z
authors.lastname: Gu
authors.forename: Yuanjin
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D001773:Blood Cells / Q000166:cytology* / Q000378:metabolism; D002469:Cell Separation / Q000379:methods*; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D055095:Optics and Photonics
chemical_list: D020100:Hydrogels