title: Hepatocellular carcinoma in nonalcoholic fatty liver disease mimicking benign hemangioma: two case reports and literature review.
abstract: OBJECTIVE
  To study the clinical features of nonalcoholic fatty liver disease (NAFLD)-associated hepatocellular carcinoma (HCC).
  
  
  METHODS
  The clinical manifestations, imaging features, pathological subtypes and treatment outcome of two cases with NAFLD-associated HCC were analyzed.
  
  
  RESULTS
  In these two cases, both were young, obese male patients, with contrast enhanced CT scan of hemangioma-like features. They had undergone surgical resection and both were reported as well-differentiated HCC pathologically. They were followed-up respectively up to 46 and 36 months post-operatively with no evidence of recurrence or metastasis.
  
  
  CONCLUSIONS
  NAFLD-associated HCC has different radiological presentations from typical HCC. Incidental finding of any liver occupying lesions in NAFLD patients should raise immediate clinical attention.
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Haidong
authors.initials: H
authors.lastname: Tan
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Li
authors.initials: L
authors.lastname: Xu
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Shuang
authors.initials: S
authors.lastname: Si
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Yongliang
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Liguo
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Wenying
authors.initials: W
authors.lastname: Zhou
authors.affiliation: Department of Hepatopancreatobiliary Surgery, China-Japan Friendship Hospital Beijing 100029, P. R. China.
authors.forename: Zhiying
authors.initials: Z
authors.lastname: Yang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D006528:Carcinoma, Hepatocellular / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D002454:Cell Differentiation; D003937:Diagnosis, Differential; D006391:Hemangioma / Q000473:pathology*; D006498:Hepatectomy; D006801:Humans; D008113:Liver Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D008297:Male; D065626:Non-alcoholic Fatty Liver Disease / Q000473:pathology* / Q000601:surgery; D011237:Predictive Value of Tests; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor
keywords: Non-alcoholic fatty liver disease (NAFLD); Nonalcoholic steatohepatitis (NASH); hepatocellular carcinoma (HCC)
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