title: Clinical Approach to Diagnosis and Management of Ovarian, Fallopian Tube, and Peritoneal Carcinoma.
abstract: Ovarian, fallopian tube and peritoneal carcinomas make up the deadliest group of malignancies of the female genital tract. Ovarian carcinoma is the second most common malignancy of the female reproductive tract in developed countries and the sixth most common cancer diagnosed in women in the United States. While signs and symptoms of ovarian carcinoma related to the mass-effect of advanced disease are relatively common, no reliable signs or symptoms are seen in patients with early ovarian carcinoma. The diagnosis can only be made by surgical removal and pathologic evaluation of a suspicious mass. The authors present an overview of the disease and discussions of genetic predisposition, prevention, screening, and diagnosis of ovarian, fallopian tube and primary peritoneal carcinomas. Details on staging procedures as well as surgical and chemotherapeutic techniques are outlined for the various stages of disease.
authors.affiliation: The Women's Institute for Gynecologic Cancer & Special Pelvic Surgery, 755 Memorial Parkway, Phillipsburg, NJ 08865, USA. Electronic address: dsilver@upthevolume.org.
authors.forename: David F
authors.initials: DF
authors.lastname: Silver
authors.affiliation: Gynecologic Service, Department of Surgery, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA.
authors.forename: Dennis S
authors.initials: DS
authors.lastname: Chi
authors.affiliation: The Women's Institute for Gynecologic Cancer & Special Pelvic Surgery, 755 Memorial Parkway, Phillipsburg, NJ 08865, USA.
authors.forename: Nadim
authors.initials: N
authors.lastname: Bou-Zgheib
keywords: Chemotherapy; Cytoreductive surgery; Epidemiology; Fallopian tube cancer; Genetic screening; Ovarian cancer; Primary peritoneal cancer; Staging procedures