title: Smoking increases the risk of early meniscus repair failure.
abstract: OBJECTIVE
  The goal of this study is to determine whether patients who smoke cigarettes at the time of surgery are at significantly increased risk of early meniscus repair failure relative to non-smokers.
  
  
  METHODS
  Retrospective chart review identified 64 current smokers within a series of 444 consecutive patients who underwent meniscus repair during a 7 years period. Fifty-two of these 64 smokers were available for follow-up and were matched by age, sex, and ACL status with non-smokers from the same cohort. Records of these 104 patients with a total of 120 meniscus repairs were reviewed to identify meniscus repair failure (defined as repeat surgery on the index meniscus) during the median 13-month (range: 3-79 months) follow-up period.
  
  
  RESULTS
  The smoking and non-smoking groups were similar in age, sex, ACL status, BMI, meniscus repair technique, and meniscus involved. Meniscus repair failure occurred in 19 of the 112 menisci in 104 patients, for an overall failure risk of 17 %. Of the 19 failures, 14 occurred in 79 repaired medial menisci (18 % failure risk) and 5 occurred in 33 repaired lateral menisci (15 % failure risk). Meniscus repair failure occurred in significantly more smokers (15 failures in 56 menisci in 52 patients -27 % failure risk) than non-smokers (4 failures in 56 menisci in 52 patients -7 % failure risk) (p = 0.0076).
  
  
  CONCLUSIONS
  Smoking is associated with significantly increased risk of early meniscus repair failure as defined by the incidence of repeat surgery on the index meniscus.
  
  
  METHODS
  III.
authors.affiliation: College of Medicine, The Ohio State University, Columbus, OH, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Blackwell
authors.affiliation: Division of Physical Therapy, School of Health and Rehabilitation Sciences, The Ohio State University, Columbus, OH, USA.
authors.forename: Laura C
authors.initials: LC
authors.lastname: Schmitt
authors.affiliation: OSU Sports Medicine, Sports Health and Performance Institute, The Ohio State University, Columbus, OH, USA.|Department of Orthopaedics, The Ohio State University, 2050 Kenny Rd, Columbus, OH, 43214, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Flanigan
authors.affiliation: OSU Sports Medicine, Sports Health and Performance Institute, The Ohio State University, Columbus, OH, USA. robert.magnussen@gmail.com.|Department of Orthopaedics, The Ohio State University, 2050 Kenny Rd, Columbus, OH, 43214, USA. robert.magnussen@gmail.com.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Magnussen
mesh_terms: D000328:Adult; D019645:Arthroplasty, Replacement, Knee; D001182:Arthroscopy / Q000379:methods; D005260:Female; D006801:Humans; D007718:Knee Injuries / Q000601:surgery; D008297:Male; D008485:Medical Audit; D008592:Menisci, Tibial / Q000601:surgery*; D012086:Reoperation; D012189:Retrospective Studies; D012306:Risk; D012907:Smoking / Q000009:adverse effects*; D000070600:Tibial Meniscus Injuries; D055815:Young Adult
keywords: Meniscus repair; Repeat surgery; Smoking
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