title: [Successful treatment for cryptococcal meningoencephalitis complicated by cerebral salt-wasting syndrome in a patient with chronic lymphocytic leukemia: A clinical case].
abstract: Cryptococcus neoformans is a common agent of fungal meningoencephalitis in immunocompromised patients. Cerebral salt-wasting syndrome is one of the rare causes of severe hyponatremia in patients with CNS diseases. The paper describes the first clinical case of a patient, whose onset of chronic lymphocytic leukemia was complicated by cryptococcal meningoencephalitis presenting with mental disorders and severe electrolytic imbalance. Antifungal treatment with amphotericin B and fluconazole could alleviate an infectious process and metabolic disturbances.
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia; Acad. I.P. Pavlov First Saint Petersburg State Medical University, Ministry of Health of Russia, Saint Petersburg, Russia.
authors.forename: V G
authors.initials: VG
authors.lastname: Potapenko
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: I B
authors.initials: IB
authors.lastname: Konovalenko
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: Е V
authors.initials: ЕV
authors.lastname: Oksema
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: L N
authors.initials: LN
authors.lastname: Filippova
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: E N
authors.initials: EN
authors.lastname: Dulaeva
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: N А
authors.initials: NА
authors.lastname: Derevyannykh
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: А I
authors.initials: АI
authors.lastname: Krasnoruzhsky
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Klimovich
authors.affiliation: P.N. Kashkin Research Institute of Medical Mycology, I.I. Mechnikov North-Western State Medical University, Ministry of Health of Russia, Saint-Petersburg, Russian.
authors.forename: N N
authors.initials: NN
authors.lastname: Klimko
authors.affiliation: City Clinical Hospital Thirty-One, Saint Petersburg, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Medvedeva
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use*; D015897:Comorbidity; D015725:Fluconazole / Q000627:therapeutic use; D006801:Humans; D007010:Hyponatremia / Q000453:epidemiology; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000453:epidemiology; D008297:Male; D016919:Meningitis, Cryptococcal / Q000188:drug therapy* / Q000453:epidemiology; D013577:Syndrome
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B; D015725:Fluconazole