title: Low Temperature Plasma Causes Double-Strand Break DNA Damage in Primary Epithelial Cells Cultured from a Human Prostate Tumour.
abstract: Research in the new field of plasma medicine continues to demonstrate the efficacy of low temperature plasmas for numerous biomedical applications. Responses such as reduction in cell viability and cell death for cancer therapy, cell proliferation for wound healing, and bacterial inactivation have been observed as a result of plasma treatment. In this study we applied low temperature plasma to prostate cancer primary cells and tissue to inflict irreparable DNA damage.
authors.affiliation: University of York, Departments of Physics and Biology, Heslington, York, YO10 5DD, UK.
authors.forename: Adam M
authors.initials: AM
authors.lastname: Hirst
authors.affiliation: University of York, Departments of Physics and Biology, Heslington, York, YO10 5DD, UK.
authors.forename: Fiona M
authors.initials: FM
authors.lastname: Frame
authors.affiliation: University of York, Departments of Physics and Biology, Heslington, York, YO10 5DD, UK.
authors.forename: Norman J
authors.initials: NJ
authors.lastname: Maitland
authors.affiliation: University of York, Departments of Physics and Biology, Heslington, York, YO10 5DD, UK.
authors.forename: Deborah
authors.initials: D
authors.lastname: O'Connell
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references.pmid: 16322242
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references.pmid: 21296855