title: High Seroprevalence of Toxoplasma gondii Antibody in HIV/AIDS Individuals from North of Iran.
abstract: BACKGROUND
  Toxoplasmosis in immunocompetent people is generally asymptomatic but in immunocompromised patients including HIV/AIDS, cancer patients, and organ transplant recipients, etc. it can lead to serious pathological problems. The objective of current study was to determine the seroprevalence of T. gondii IgG and IgM antibodies in HIV/AIDS patients using ELISA technique in Mazandaran Province, northern Iran.
  
  
  METHODS
  Overall, 82 serum samples (61 males and 21 females) were collected from HIV/AIDS patients in Mazandaran Provinces, in 2013. Sera were surveyed employing ELISA assay. Data were analyzed using Chi-Square or Fisher exact test. In addition, before sampling a questionnaire was filled out for each subject.
  
  
  RESULTS
  Overall seroprevalence of examined sera was 96.3% for IgG antibody but none of the sera shown IgM antibody against T. gondii. The seroprevalence of toxoplasmosis in males and females was 96.7% and 95.2%, respectively. An antibody titer of >1 IU/ml was considered as positive. Furthermore, none of the included variables statistically was significant.
  
  
  CONCLUSIONS
  Seroprevalence of chronic (latent) toxoplasmosis in HIV/AIDS patients in Mazandaran Province is high compared to toxoplasmosis in general population. Consequently, the risk of acquiring Toxoplasma encephalitis in examined seropositive HIV/AIDS patients of Toxoplasma is high.
authors.affiliation: Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Mohammad Taghi
authors.initials: MT
authors.lastname: Rahimi
authors.affiliation: Amol Faculty of Paramedics, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Seif Ali
authors.initials: SA
authors.lastname: Mahdavi
authors.affiliation: Amol Faculty of Paramedics, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Behzad
authors.initials: B
authors.lastname: Javadian
authors.affiliation: Amol Faculty of Nursing and Midwifery, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Rozita
authors.initials: R
authors.lastname: Rezaei
authors.affiliation: Health Sciences Research Center, School of Health, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Moosazadeh
authors.affiliation: Health Center Province, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Mehri
authors.initials: M
authors.lastname: Khademlou
authors.affiliation: Health Center Province, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Seyed Hosein
authors.initials: SH
authors.lastname: Seyedpour
authors.affiliation: Dep. of Medical Parasitology and Mycology, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
authors.forename: Abolghasem
authors.initials: A
authors.lastname: Syadatpanah
keywords: HIV/AIDS; Iran; Seroprevalence; Toxoplasma gondii
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