title: [Value of pulse oximetry for diagnosing obstructive sleep apnea-hypopnea syndrome and evaluation of the effect of the continuous positive airway pressure therapy].
abstract: OBJECTIVE
  To explore the value of pulse oximetry for diagnosing obstructive sleep apnea hypopnea syndrome (OSAHS) and evaluation of the effect of the continuous positive airway pressure (CPAP) therapy.
  
  
  METHODS
  From January 2013 to March 2014, 244 OSAHS patients admitted to department of respiratory and critical care medicine of the first affiliated hospital of Fujian Medical University and department of respiratory and critical care medicine of People's Hospital of Peking University were recruited. According to apnea-hypopnea index (AHI), all patients were divided into mild, moderate and severe groups. The differences in pulse-associated indicators [nocturnal pulse elevation index (NPEI), namely counts of heart rate (HR) variation >6 bpm/h, average HR and standard deviation of HR] were compared among three groups before and after CPAP therapy. Spearman correlation analysis between pulse-associated indicators and AHI was performed to explore the optimal indicator. Receiver operating characteristic (ROC) curve were conducted and sensitivity and specificity were obtained.
  
  
  RESULTS
  NPEI after CPAP treatment were significantly lower than before among all the three groups (mild group 15.4±12.4 vs 19.4±13.3, moderate group 15.4±9.1 vs 24.1±11.9, severe group 21.9±14.8 vs 48.8±20.3, all P<0.05); there were significant correlations of AHI with average HR, standard deviation of HR and NPEI (r=0.334, 0.337 and 0.660, respectively) (all P<0.05); ROC curve showed a NPEI of 30beat per hour had a sensitivity of 68.0% and a specificity of 73.0% in diagnosing OSAHS.
  
  
  CONCLUSIONS
  Nocturnal oximetry could be a useful tool for screening OSAHS in clinical practice, and the NPEI can evaluate the efficacy of the CPAP therapy.
authors.affiliation: Department of Respiratory and Critical Care Medicine, the First Affiliated Hospital of Fujian Medical University; Fujian Provincial Sleep-disordered Breathing Clinic Center; Laboratory of Respiratory Disease of Fujian Medical University; Fuzhou 350005, China.
authors.forename: Biying
authors.initials: B
authors.lastname: Wang
authors.forename: Fang
authors.initials: F
authors.lastname: Han
authors.forename: Qinghua
authors.initials: Q
authors.lastname: Li
authors.forename: Xiao
authors.initials: X
authors.lastname: Chen
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Pei
authors.initials: P
authors.lastname: An
authors.forename: Long
authors.initials: L
authors.lastname: Zhao
authors.forename: Xueli
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Email: cgp3542@163.com.
authors.forename: Gongping
authors.initials: G
authors.lastname: Chen
mesh_terms: D045422:Continuous Positive Airway Pressure; D006339:Heart Rate; D006801:Humans; D010092:Oximetry; D017286:Polysomnography; D020181:Sleep Apnea, Obstructive