title: Does the preference of peripheral versus central venous access in peripheral blood stem cell collection/yield change stem cell kinetics in autologous stem cell transplantation?
abstract: Central venous access is often used during apheresis procedure in stem cell collection. The aim of the present study was to evaluate whether central or peripheral venous access has an effect on stem cell yield and the kinetics of the procedure and the product in patients undergoing ASCT after high dose therapy. A total of 327 patients were retrospectively reviewed. The use of peripheral venous access for stem cell yield was significantly more frequent in males compared to females (p = 0.005). Total volume of the product was significantly lower in central venous access group (p = 0.046). As being a less invasive procedure, peripheral venous access can be used for stem cell yield in eligible selected patients.
authors.affiliation: Department of Hematology, Faculty of Medicine, Pamukkale University, Denizli, Turkey. Electronic address: mhdogu@yahoo.com.
authors.forename: Mehmet Hilmi
authors.initials: MH
authors.lastname: Dogu
authors.affiliation: Hematology and Stem Cell Transplantation Clinic, Ankara Oncology Education and Research Hospital, Ankara, Turkey.
authors.forename: Ali Hakan
authors.initials: AH
authors.lastname: Kaya
authors.affiliation: Department of Hematology, Faculty of Medicine, İnönü University, Malatya, Turkey.
authors.forename: Ilhami
authors.initials: I
authors.lastname: Berber
authors.affiliation: Department of Hematology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.
authors.forename: İsmail
authors.initials: İ
authors.lastname: Sari
authors.affiliation: Hematology and Stem Cell Transplantation Clinic, Ankara Oncology Education and Research Hospital, Ankara, Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Tekgündüz
authors.affiliation: Department of Hematology, Faculty of Medicine, İnönü University, Malatya, Turkey.
authors.forename: Mehmet Ali
authors.initials: MA
authors.lastname: Erkurt
authors.affiliation: Hematology and Stem Cell Transplantation Clinic, Ankara Oncology Education and Research Hospital, Ankara, Turkey.
authors.forename: Dicle
authors.initials: D
authors.lastname: Iskender
authors.affiliation: Hematology and Stem Cell Transplantation Clinic, Ankara Oncology Education and Research Hospital, Ankara, Turkey.
authors.forename: Ömur
authors.initials: Ö
authors.lastname: Kayıkçı
authors.affiliation: Department of Hematology, Faculty of Medicine, İnönü University, Malatya, Turkey.
authors.forename: Irfan
authors.initials: I
authors.lastname: Kuku
authors.affiliation: Department of Hematology, Faculty of Medicine, İnönü University, Malatya, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Kaya
authors.affiliation: Department of Hematology, Faculty of Medicine, Pamukkale University, Denizli, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Keskin
authors.affiliation: Medical Faculty, Department of Internal Medicine, Division of Hematology, Yıldırım Beyazıt University, Ankara, Turkey.
authors.forename: Fevzi
authors.initials: F
authors.lastname: Altuntaş
mesh_terms: D001800:Blood Specimen Collection / Q000379:methods*; D002755:Choice Behavior; D003710:Demography; D005260:Female; D006801:Humans; D007700:Kinetics; D008297:Male; D008875:Middle Aged; D036102:Peripheral Blood Stem Cell Transplantation; D000072916:Peripheral Blood Stem Cells / Q000166:cytology*; D014182:Transplantation, Autologous
keywords: Apheresis; Autologous stem cell transplantation; Mobilization