title: [Infection post Excimer Laser Corneal Refractive Surgery].
abstract: OBJECTIVE
  To report the cases with severe infection post excimer laser refractive surgery.
  
  
  METHODS
  This study involved 6 eyes of 4 women (mean age 38 years, range : 27-51 years) who underwent excimer laser corneal refractive surgery.
  
  
  RESULTS
  In all 4 cases, the respective primary causative organisms of the infection were quinolone-resistant methicillin-sensitive Staphylococcus aureus, quinolone-resistant methicillin-resistant Staphylococcus aureus, yeast type fungus, and in 1 case, penicillin-resistant Streptococcus pneumoniae. We initiated topical antibiotics or intensive antifungal treatment, yet due to severe inflammation and ophthalmalgia, analgesic drugs were needed. An average hospitalization period was 38.5 days (range : 22-77 days), and the best spectacle-corrected visual acuity was 0.5 or more than 0.5 post discharge.
  
  
  CONCLUSIONS
  In the treatment of severe corneal infection post refractive surgery, it is important to identify the primary causative organism. If the response to the initial treatment is poor, such patients should immediately be referred to a special clinic to obtain a better visual outcome.
authors.forename: Osamu
authors.initials: O
authors.lastname: Hieda
authors.forename: Chie
authors.initials: C
authors.lastname: Sotozono
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakamura
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kinoshita
mesh_terms: D000328:Adult; D001251:Astigmatism / Q000503:physiopathology / Q000601:surgery*; D015818:Eye Infections, Bacterial / Q000382:microbiology*; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000009:adverse effects; D054018:Lasers, Excimer / Q000009:adverse effects*; D055624:Methicillin-Resistant Staphylococcus aureus; D008875:Middle Aged; D013203:Staphylococcal Infections / Q000382:microbiology*; D014792:Visual Acuity