title: Predictive Validity of the Premie-Neuro at 3 Months' Adjusted Age and 2 Years' Chronological Age.
abstract: BACKGROUND
  It is difficult to predict which preterm babies are most at risk for poor neurodevelopmental outcomes. A quick, highly predictive assessment tool would aid neonatal clinicians in making decisions about follow-up care.
  
  
  OBJECTIVE
  The purpose of this study was to determine whether performance on the Premie-Neuro in the neonatal intensive care unit predicted neurodevelopmental outcomes at 3 months' adjusted age and 24 months' chronological age.
  
  
  METHODS
  Thirty-four preterm infants were administered the Premie-Neuro in the neonatal intensive care unit. Infants were assessed using the Infanib and Alberta Infant Motor Scales at 3 months' adjusted age, and using the Bayley Scales of Infant and Toddler Development, Third edition (Bayley-III) at 24 months' chronological age. Scores were analyzed to determine whether Premie-Neuro performance at less than 37 weeks postmenstrual age was predictive of neurodevelopmental outcomes at 3 months' adjusted age and 24 months' chronological age.
  
  
  RESULTS
  Premie-Neuro raw scores were predictive of outcomes at 3 months' adjusted age and 24 months' chronological age. Premie-Neuro classifications were not predictive of Infanib and Alberta Infant Motor Scale classifications at 3 months' adjusted age but were predictive of Bayley-III classification at 24 months' chronological age.
  
  
  CONCLUSIONS
  Premie-Neuro raw scores may be used by the clinician to identify infants at risk for neurodevelopmental delays. Premie-Neuro classifications should be interpreted cautiously.
  
  
  CONCLUSIONS
  More research is needed to determine whether the Premie-Neuro may be used as an adjunct to clinical assessment to identify infants who are most at risk for developmental delay.
authors.affiliation: Department of Physical Therapy Education, Rockhurst University, Kansas City, Missouri (Dr Gagnon); Center for Child Health and Development, University of Kansas Medical Center, Kansas City (Dr Cannon); and Neonatal Intensive Care Services, Sunflower Neonatology Associates, Overland Park Regional Medical Center, Overland Park, Kansas (Dr Weatherstone).
authors.forename: Kendra
authors.initials: K
authors.lastname: Gagnon
authors.forename: Susan
authors.initials: S
authors.lastname: Cannon
authors.forename: Kathleen B
authors.initials: KB
authors.lastname: Weatherstone
mesh_terms: D000359:Aftercare; D002657:Child Development; D002675:Child, Preschool; D002658:Developmental Disabilities / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D008137:Longitudinal Studies; D008297:Male; D009048:Motor Skills; D065886:Neurodevelopmental Disorders / Q000175:diagnosis / Q000453:epidemiology; D009460:Neurologic Examination / Q000379:methods*; D015203:Reproducibility of Results; D018570:Risk Assessment