title: ¹⁸F-FDG PET/CT for Staging and Restaging of Breast Cancer.
abstract: Many studies have pointed out the role of (18)F-FDG PET/CT (or (18)F-FDG PET) in patients with clinical stage III or II breast cancer. (18)F-FDG PET/CT might advantageously replace other staging procedures, such as bone scanning and possibly contrast-enhanced CT of the thorax or abdomen-pelvis. We discuss the findings, locoregional or distant, that can be expected in different categories of breast cancer and their impact on prognosis and management. We also discuss the role of (18)F-FDG PET/CT in restaging and how (18)F-FDG PET/CT compares with conventional techniques in restaging for patients with suspected disease recurrence. We conclude with some recommendations for clinical practice and future research.
authors.affiliation: Department of Nuclear Medicine, Saint-Louis Hospital, Paris, France dgroheux@yahoo.fr.
authors.forename: David
authors.initials: D
authors.lastname: Groheux
authors.affiliation: Department of Nuclear Medicine, Centre GF Leclerc, Dijon, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Cochet
authors.affiliation: Department of Nuclear Medicine, Centre GF Leclerc, Dijon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Humbert
authors.affiliation: Department of Nuclear Medicine, Institut Curie, Paris, France.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Alberini
authors.affiliation: Department of Nuclear Medicine, University of Bordeaux, Hôpital Haut-Lévêque CHU, Bordeaux, France; and.
authors.forename: Elif
authors.initials: E
authors.lastname: Hindié
authors.affiliation: Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: David
authors.initials: D
authors.lastname: Mankoff
mesh_terms: D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D064847:Multimodal Imaging; D009367:Neoplasm Staging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D011379:Prognosis; D019275:Radiopharmaceuticals; D014057:Tomography, X-Ray Computed
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: 18F-FDG PET/CT; breast cancer; prognosis; restaging; staging