title: Long-Term Outcomes of Patients with Acute Cholecystitis after Successful Percutaneous Cholecystostomy Treatment and the Risk Factors for Recurrence: A Decade Experience at a Single Center.
abstract: BACKGROUND
  Percutaneous cholecystostomy tube (PCT) has been effectively used for the treatment of acute cholecystitis (AC) for patients unsuitable for early cholecystectomy. This retrospective study investigated the recurrence rate after successful PCT treatment and factors associated with recurrence.
  
  
  METHODS
  We reviewed patients treated with PCT for AC from October 2004 through December 2013. Patients with successful PCT treatment were those who were free from persistent PCT drainage. We used multivariable logistic regression analysis sequentially to identify factors associated with each outcome.
  
  
  RESULTS
  The study included 184 patients (mean age: 70.1 years). The average duration for parenteral antibiotics was 14.4 days and 20.0 days for PCT drainage. The one-year recurrence rate was 9.2% (17/184) with most recurrences occurring within two months (6.5%, 12/184) of the procedure. Complicated cholecystitis (odds ratio [OR]: 4.67; 95% confidence interval [CI]: 1.44-15.70; P = 0.01) and PCT drainage duration >32 days (OR: 4.92; 95% CI: 1.03-23.53; P = 0.05) positively correlated with one-year recurrence; parenteral antibiotics duration >10 days (OR: 0.21; 95% CI: 0.05-0.68; P = 0.01) was inversely associated with one-year recurrence.
  
  
  CONCLUSIONS
  The recurrence rate was low for patients after successful PCT treatment. Predictors for recurrence included the severity of initial AC and subsequently provided treatments.
authors.affiliation: Department of Emergency Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Chih-Hung
authors.initials: CH
authors.lastname: Wang
authors.affiliation: Department of Emergency Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Cheng-Yi
authors.initials: CY
authors.lastname: Wu
authors.affiliation: Department of Medical Imaging, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Justin Cheng-Ta
authors.initials: JC
authors.lastname: Yang
authors.affiliation: National Taiwan University Hospital, Hsin-Chu Branch and National Taiwan University, Hsinchu City, Taiwan.
authors.forename: Wan-Ching
authors.initials: WC
authors.lastname: Lien
authors.affiliation: Department of Internal Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Hsiu-Po
authors.initials: HP
authors.lastname: Wang
authors.affiliation: Department of Medical Imaging, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Kao-Lang
authors.initials: KL
authors.lastname: Liu
authors.affiliation: Department of Surgery, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Yao-Ming
authors.initials: YM
authors.lastname: Wu
authors.affiliation: Department of Emergency Medicine, National Taiwan University and National Taiwan University Hospital, Taipei, Taiwan.
authors.forename: Shyr-Chyr
authors.initials: SC
authors.lastname: Chen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D041881:Cholecystitis, Acute / Q000453:epidemiology / Q000473:pathology* / Q000601:surgery*; D002767:Cholecystostomy; D005260:Female; D005704:Gallbladder / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D016896:Treatment Outcome
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