title: Familiar environments enhance object and spatial memory in both younger and older adults.
abstract: Recent evidence suggests that familiarity with an environment may protect against spatial memory decline for familiar objects in older adults. We investigated whether a familiar context also reduces age-related decline in spatial memory for novel objects. Twenty-four younger and 23 older participants viewed a virtual rendering of a local environment along two different routes, each through a well-known (West) or lesser-known (East) area within the environment. Older and younger participants reported being more familiar with one (i.e. West) area than the other. In each trial, participants were presented with one route and were instructed to learn ten novel objects and their locations along the route. Following learning, participants immediately completed five test blocks: an object recognition task, an egocentric spatial processing (direction judgement) task, an allocentric spatial processing (proximity judgement) task and two pen-and-paper tests to measure cognitive mapping abilities. First we found an age effect with worse performance by older than younger adults in all spatial tasks, particularly in allocentric spatial processing. However, our results suggested better memory for objects and directions, but not proximity judgements, when the task was associated with more familiar than unfamiliar contexts, in both age groups. There was no benefit of context when a separate young adult group (N = 24) was tested, who reported being equally familiar with both areas. These results suggest an important facilitatory role of context familiarity on object recognition, and in particular egocentric spatial memory, and have implications for enhancing spatial memory in older adults.
authors.affiliation: School of Psychology and Institute of Neuroscience, Lloyd Building, Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Niamh A
authors.initials: NA
authors.lastname: Merriman
authors.affiliation: Graphics, Vision and Visualisation Group, School of Computer Science and Statistics, Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Jan
authors.initials: J
authors.lastname: Ondřej
authors.affiliation: School of Psychology and Institute of Neuroscience, Lloyd Building, Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Eugenie
authors.initials: E
authors.lastname: Roudaia
authors.affiliation: Graphics, Vision and Visualisation Group, School of Computer Science and Statistics, Trinity College Dublin, Dublin 2, Ireland.
authors.forename: Carol
authors.initials: C
authors.lastname: O'Sullivan
authors.affiliation: School of Psychology and Institute of Neuroscience, Lloyd Building, Trinity College Dublin, Dublin 2, Ireland. fiona.newell@tcd.ie.
authors.forename: Fiona N
authors.initials: FN
authors.lastname: Newell
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000375:Aging / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D021641:Recognition, Psychology / Q000502:physiology*; D065853:Spatial Learning / Q000502:physiology*; D065852:Spatial Memory / Q000502:physiology*; D065854:Spatial Navigation / Q000502:physiology*; D055815:Young Adult
keywords: Ageing; Familiarity context effects; Recognition; Spatial navigation; Virtual reality
references.citation: Front Aging Neurosci. 2012 Nov 01;4:29
references.pmid: 23125833
references.citation: Behav Brain Res. 2010 May 1;209(1):49-58
references.pmid: 20085784
references.citation: J Neurosci. 2007 Jun 6;27(23):6141-9
references.pmid: 17553986
references.citation: Trends Neurosci. 2012 Apr;35(4):211-9
references.pmid: 22398180
references.citation: J Comp Neurol. 1994 Dec 22;350(4):497-533
references.pmid: 7890828
references.citation: Psychol Aging. 1997 Jun;12(2):372-5
references.pmid: 9189997
references.citation: J Exp Psychol Learn Mem Cogn. 2016 Feb;42(2):308-15
references.pmid: 26375782
references.citation: Neurobiol Aging. 2012 Jan;33(1):202.e15-22
references.pmid: 20832911
references.citation: Psychol Rev. 1996 Jul;103(3):403-28
references.pmid: 8759042
references.citation: J Cogn Neurosci. 2006 Apr;18(4):495-507
references.pmid: 16768356
references.citation: Neurobiol Aging. 2006 Jul;27(7):965-72
references.pmid: 15982787
references.citation: Philos Trans R Soc Lond B Biol Sci. 2013 Dec 23;369(1635):20120533
references.pmid: 24366141
references.citation: Cyberpsychol Behav. 2009 Aug;12(4):423-7
references.pmid: 19514820
references.citation: Hippocampus. 2004;14(2):180-92
references.pmid: 15098724
references.citation: Hippocampus. 2007;17(12):1241-51
references.pmid: 17853413
references.citation: Curr Opin Neurobiol. 1999 Dec;9(6):708-12
references.pmid: 10607650
references.citation: Cereb Cortex. 2007 Jul;17(7):1493-503
references.pmid: 16990438
references.citation: Cereb Cortex. 2004 Apr;14(4):364-75
references.pmid: 15028641
references.citation: J Gerontol B Psychol Sci Soc Sci. 2002 Mar;57(2):P101-15
references.pmid: 11867658
references.citation: J Int Neuropsychol Soc. 2005 Mar;11(2):144-51
references.pmid: 15962702
references.citation: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2010;17(4):385-405
references.pmid: 19851899
references.citation: Neurobiol Aging. 2001 Sep-Oct;22(5):787-96
references.pmid: 11705638
references.citation: Psychol Rev. 1948 Jul;55(4):189-208
references.pmid: 18870876
references.citation: Trends Cogn Sci. 2007 Dec;11(12):520-7
references.pmid: 18024143
references.citation: Memory. 2009 Feb;17(2):125-43
references.pmid: 18608980
references.citation: Neurobiol Learn Mem. 1996 Jan;65(1):65-72
references.pmid: 8673408
references.citation: Neuropsychol Rev. 2009 Dec;19(4):478-89
references.pmid: 19936933
references.citation: Nat Neurosci. 2004 Jun;7(6):673-7
references.pmid: 15146191
references.citation: Cogn Psychol. 1982 Oct;14(4):560-89
references.pmid: 7140211
references.citation: J Am Geriatr Soc. 2005 Apr;53(4):695-9
references.pmid: 15817019
references.citation: Psychol Aging. 1991 Mar;6(1):10-8
references.pmid: 2029357
references.citation: Mem Cognit. 2007 Jul;35(5):910-24
references.pmid: 17910176
references.citation: Neuroimage. 2010 Nov 1;53(2):725-35
references.pmid: 20603219
references.citation: Hippocampus. 2012 Apr;22(4):842-52
references.pmid: 21584904
references.citation: Science. 1998 May 8;280(5365):921-4
references.pmid: 9572740
references.citation: Neuron. 2003 Mar 6;37(5):877-88
references.pmid: 12628177
references.citation: Annu Rev Psychol. 2009;60:173-96
references.pmid: 19035823
references.citation: Exp Aging Res. 1983 Fall;9(3):169-73
references.pmid: 6641777
references.citation: J Neurosci. 2013 Apr 3;33(14):6012-7
references.pmid: 23554482
references.citation: Cognition. 2007 Aug;104(2):231-53
references.pmid: 16879816
references.citation: Exp Brain Res. 2011 Jan;208(1):61-71
references.pmid: 20972774
references.citation: Neuropsychologia. 1996 Oct;34(10):993-1001
references.pmid: 8843066
references.citation: Aging Clin Exp Res. 2013 May;25(2):203-9
references.pmid: 23739906
references.citation: J Neurophysiol. 2007 May;97(5):3670-83
references.pmid: 17376855
references.citation: Proc Natl Acad Sci U S A. 2000 Apr 11;97(8):4398-403
references.pmid: 10716738
references.citation: J Exp Psychol Learn Mem Cogn. 2014 Mar;40(2):459-75
references.pmid: 24219084
references.citation: AJNR Am J Neuroradiol. 2003 Oct;24(9):1849-56
references.pmid: 14561615
references.citation: Neuroimage. 2010 Jun;51(2):501-11
references.pmid: 20298790
references.citation: J Neurosci. 2003 Jul 2;23(13):5945-52
references.pmid: 12843299
references.citation: J Exp Psychol Gen. 1998 Dec;127(4):398-415
references.pmid: 9857494
references.citation: Front Aging Neurosci. 2012 Sep 13;4:25
references.pmid: 22993506
references.citation: Cereb Cortex. 2014 Apr;24(4):883-97
references.pmid: 23211209
references.citation: J Environ Psychol. 2010 Dec;30(4-2):565-573
references.pmid: 21151353
references.citation: J Cogn Neurosci. 2005 Jan;17(1):73-83
references.pmid: 15701240
references.citation: Neurology. 2008 Sep 16;71(12):888-95
references.pmid: 18794491
references.citation: J Neurosci. 2005 Mar 30;25(13):3333-40
references.pmid: 15800188
references.citation: Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2013;20(3):298-319
references.pmid: 22901081
references.citation: Behav Processes. 2001 Mar 13;53(1-2):75-85
references.pmid: 11254994
references.citation: Psychol Aging. 2011 Sep;26(3):671-7
references.pmid: 21443351
references.citation: Disabil Rehabil. 2013 Aug;35(16):1371-9
references.pmid: 23244232
references.citation: J Neurosci. 2011 May 18;31(20):7441-9
references.pmid: 21593327
references.citation: Exp Aging Res. 1989 Autumn-Winter;15(3-4):181-7
references.pmid: 2638637
references.citation: Behav Brain Res. 2009 Jan 23;196(2):187-91
references.pmid: 18817815
references.citation: Hippocampus. 2013 Nov;23(11):1005-14
references.pmid: 23929534
references.citation: Neurobiol Aging. 2012 Mar;33(3):620.e9-620.e22
references.pmid: 21497950
references.citation: Neuroimage. 2004 Aug;22(4):1503-14
references.pmid: 15275907
references.citation: Behav Neurosci. 2002 Oct;116(5):851-9
references.pmid: 12369805
references.citation: Brain Res. 2011 Sep 2;1410:112-9
references.pmid: 21803342
references.citation: Hippocampus. 2007;17(9):873-89
references.pmid: 17604348
references.citation: Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):2157-62
references.pmid: 12578977
references.citation: Cereb Cortex. 2003 Dec;13(12):1344-51
references.pmid: 14615299
references.citation: Neuroimage. 2015 Aug 15;117:141-50
references.pmid: 26003855
references.citation: Psychol Rev. 2007 Apr;114(2):340-75
references.pmid: 17500630
references.citation: Nature. 1998 Apr 9;392(6676):598-601
references.pmid: 9560155
references.citation: Int J Geriatr Psychiatry. 2009 Feb;24(2):197-201
references.pmid: 18850670
references.citation: Cogn Process. 2015 Sep;16 Suppl 1:313-7
references.pmid: 26224272
references.citation: J Neurosci. 2009 Jun 3;29(22):7208-19
references.pmid: 19494143
references.citation: Curr Biol. 2014 Jun 16;24(12 ):1331-1340
references.pmid: 24909328
references.citation: Front Aging Neurosci. 2012 May 21;4:7
references.pmid: 22661944