title: Synthesis and Anti-Platelet Activity of Thiosulfonate Derivatives Containing a Quinone Moiety.
abstract: Thiosulfonate derivatives based on quinones were synthesized for studying "structure-activity relationship" compounds with an acylated and a free amino-group. Anti-platelet activity of the synthesized compounds was determined and the influence of substituents on the activity of the derivatives was assessed.
authors.affiliation: Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera Str. 12, 79013, Lviv, Ukraine.
authors.forename: Khrystyna
authors.initials: K
authors.lastname: Bolibrukh
authors.affiliation: Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera Str. 12, 79013, Lviv, Ukraine.
authors.forename: Svyatoslav
authors.initials: S
authors.lastname: Polovkovych
authors.affiliation: Laboratoire de Pharmaco-Chimie Radicalaire, Institut de Chimie Radicalaire ICR, Faculté de Pharmacie, Aix-Marseille Univ, CNRS, UMR 7273, Bd J. Moulin 27, 13385, Marseille Cedex 05, France.
authors.forename: Omar
authors.initials: O
authors.lastname: Khoumeri
authors.affiliation: Educational and Scientific centre "Institute of Biology", Taras Shevchenko National University of Kyiv, Volodymyrska Str. 64/13, 01601, Kyiv, Ukraine.
authors.forename: Tetyana
authors.initials: T
authors.lastname: Halenova
authors.affiliation: Educational and Scientific centre "Institute of Biology", Taras Shevchenko National University of Kyiv, Volodymyrska Str. 64/13, 01601, Kyiv, Ukraine.
authors.forename: Irina
authors.initials: I
authors.lastname: Nikolaeva
authors.affiliation: Educational and Scientific centre "Institute of Biology", Taras Shevchenko National University of Kyiv, Volodymyrska Str. 64/13, 01601, Kyiv, Ukraine.
authors.forename: Olexiy
authors.initials: O
authors.lastname: Savchuk
authors.affiliation: Laboratoire de Pharmaco-Chimie Radicalaire, Institut de Chimie Radicalaire ICR, Faculté de Pharmacie, Aix-Marseille Univ, CNRS, UMR 7273, Bd J. Moulin 27, 13385, Marseille Cedex 05, France.
authors.forename: Thierry
authors.initials: T
authors.lastname: Terme
authors.affiliation: Laboratoire de Pharmaco-Chimie Radicalaire, Institut de Chimie Radicalaire ICR, Faculté de Pharmacie, Aix-Marseille Univ, CNRS, UMR 7273, Bd J. Moulin 27, 13385, Marseille Cedex 05, France.
authors.forename: Patrice
authors.initials: P
authors.lastname: Vanelle
authors.affiliation: Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera Str. 12, 79013, Lviv, Ukraine.
authors.forename: Vira
authors.initials: V
authors.lastname: Lubenets
authors.affiliation: Department of Technology of Biologically Active Substances, Pharmacy and Biotechnology, Lviv Polytechnic National University, Bandera Str. 12, 79013, Lviv, Ukraine.
authors.forename: Volodymyr
authors.initials: V
authors.lastname: Novikov
keywords: Anti-platelet activity; Quinone; Thiosulfonate
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