title: Gene Regulation: Stable Noise.
abstract: Transcriptional regulation is noisy, yet despite this variability, embryonic development reproducibly generates form and function. Recent work demonstrates that patterns of transcriptional activity in embryos are stably inherited through mitosis. These observations have implications for how accuracy arises in development.
authors.affiliation: MRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK. Electronic address: j.chubb@ucl.ac.uk.
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Chubb
mesh_terms: D047108:Embryonic Development / Q000235:genetics; D005786:Gene Expression Regulation; D018507:Gene Expression Regulation, Developmental; D009622:Noise; D011506:Proteins / Q000378:metabolism; D015533:Transcriptional Activation
chemical_list: D011506:Proteins