title: Effects of diet containing flaxseed flour (Linum usitatissimum) on body adiposity and bone health in young male rats.
abstract: Flaxseed flour has been described as an excellent alpha-linolenic acid source. This study was designed to evaluate the effects of flaxseed flour on body adiposity and bone health in rats fed a flaxseed flour diet during lactation until 90 days. At birth, male Wistar rats were randomly assigned to control (C) and experimental (FF) groups, whose dams were treated with a control or flaxseed flour diet, respectively, during lactation. At 21 days, pups were weaned and fed a control and experimental diet until 90 days. Food intake, body mass and length were evaluated during a 21-90 day period. At 90 days, composition by dual-energy X-ray absorptiometry, serum hormonal profile, intra-abdominal fat mass, and lumbar vertebra and femur analyses was determined. Differences were deemed significant at p < 0.05. The FF group displayed the following (P < 0.05): a higher total lean mass (+7%), a lower total (-16%) and intra-abdominal (-24%) fat mass, a smaller adipocyte area (-30%), a higher femoral mass (+5%), bone mineral density (+5%) and radiodensity (+20%), and a higher maximum force (+10%) and breaking strength (+11%). The flaxseed flour diet displayed functional properties related to body growth maintenance associated with a lower risk of developing metabolic alterations, obesity and bone fragility.
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Carlos Alberto Soares
authors.initials: CA
authors.lastname: da Costa
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Paula Cristina Alves
authors.initials: PC
authors.lastname: da Silva
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Danielle Cavalcante
authors.initials: DC
authors.lastname: Ribeiro
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Aline D'Avila
authors.initials: AD
authors.lastname: Pereira
authors.affiliation: Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Aline de Sousa
authors.initials: Ade S
authors.lastname: dos Santos
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Maíra Duque Coutinho
authors.initials: MD
authors.lastname: de Abreu
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Letícia Rozeno
authors.initials: LR
authors.lastname: Pessoa
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Bianca Ferolla da Camara
authors.initials: BF
authors.lastname: Boueri
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Carolina Ribeiro
authors.initials: CR
authors.lastname: Pessanha
authors.affiliation: Physiological Sciences, Institute of Biology Roberto Alcantara Gomes, State University of Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Celly Cristina Alves
authors.initials: CC
authors.lastname: do Nascimento-Saba
authors.affiliation: Analytical Laboratory of Restorative Biomaterials, Dental School, Fluminense Federal University, Niteroi, RJ, Brazil.
authors.forename: Eduardo Moreira
authors.initials: EM
authors.lastname: da Silva
authors.affiliation: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niteroi, RJ, Brazil. nutcarlos@hotmail.com.
authors.forename: Gilson Teles
authors.initials: GT
authors.lastname: Boaventura
mesh_terms: D050153:Abdominal Fat / Q000378:metabolism; D015502:Absorptiometry, Photon; D050154:Adiposity; D000818:Animals; D015519:Bone Density; D001842:Bone and Bones / Q000737:chemistry* / Q000378:metabolism; D005260:Female; D019597:Flax / Q000737:chemistry / Q000378:metabolism*; D005433:Flour / Q000032:analysis*; D008297:Male; D051381:Rats; D017208:Rats, Wistar