title: Point-of-care diagnostics for niche applications.
abstract: Point-of-care or point-of-use diagnostics are analytical devices that provide clinically relevant information without the need for a core clinical laboratory. In this review we define point-of-care diagnostics as portable versions of assays performed in a traditional clinical chemistry laboratory. This review discusses five areas relevant to human and animal health where increased attention could produce significant impact: veterinary medicine, space travel, sports medicine, emergency medicine, and operating room efficiency. For each of these areas, clinical need, available commercial products, and ongoing research into new devices are highlighted.
authors.affiliation: Joint Department of Biomedical Engineering, University of North Carolina - Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Cummins
authors.affiliation: Joint Department of Biomedical Engineering, University of North Carolina - Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA.
authors.forename: Frances S
authors.initials: FS
authors.lastname: Ligler
authors.affiliation: Joint Department of Biomedical Engineering, University of North Carolina - Chapel Hill and North Carolina State University, Raleigh, NC, 27695, USA. Electronic address: gmwalker@ncsu.edu.
authors.forename: Glenn M
authors.initials: GM
authors.lastname: Walker
mesh_terms: D000818:Animals; D004636:Emergency Service, Hospital / Q000458:organization & administration; D006801:Humans; D009873:Operating Rooms / Q000458:organization & administration; D019095:Point-of-Care Systems / Q000706:statistics & numerical data* / Q000639:trends; D013026:Space Flight; D013178:Sports Medicine; D014730:Veterinary Medicine
keywords: Diagnostics; Emergency care; Operating room; Point-of-care; Space travel; Sports medicine; Veterinary
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