title: Transformation of ALK rearrangement-positive adenocarcinoma to small-cell lung cancer in association with acquired resistance to alectinib.
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama.
authors.forename: N
authors.initials: N
authors.lastname: Takegawa
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama hayashi_h@dotd.med.kindai.ac.jp.
authors.forename: H
authors.initials: H
authors.lastname: Hayashi
authors.affiliation: Department of Pathology, Kishiwada City Hospital, Kishiwada, Japan.
authors.forename: N
authors.initials: N
authors.lastname: Iizuka
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama.
authors.forename: T
authors.initials: T
authors.lastname: Takahama
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama.
authors.forename: H
authors.initials: H
authors.lastname: Ueda
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama.
authors.forename: K
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama.
authors.forename: M
authors.initials: M
authors.lastname: Takeda
authors.affiliation: Department of Medical Oncology, Kinki University Faculty of Medicine, Osaka-Sayama.
authors.forename: K
authors.initials: K
authors.lastname: Nakagawa
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D000328:Adult; D000077548:Anaplastic Lymphoma Kinase; D002227:Carbazoles / Q000494:pharmacology / Q000627:therapeutic use*; D002471:Cell Transformation, Neoplastic / Q000187:drug effects / Q000235:genetics / Q000473:pathology; D018450:Disease Progression; D019008:Drug Resistance, Neoplasm / Q000187:drug effects* / Q000235:genetics; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology; D010880:Piperidines / Q000494:pharmacology / Q000627:therapeutic use*; D047428:Protein Kinase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D020794:Receptor Protein-Tyrosine Kinases / Q000235:genetics; D055752:Small Cell Lung Carcinoma / Q000188:drug therapy* / Q000235:genetics / Q000473:pathology
chemical_list: D002227:Carbazoles; D010880:Piperidines; D047428:Protein Kinase Inhibitors; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases; C582670:alectinib