title: Evaluation of BEBIG HDR (60)Co system for non-invasive image-guided breast brachytherapy.
abstract: OBJECTIVE
  HDR (60)Co system has recently been developed and utilized for brachytherapy in many countries outside of the U.S. as an alternative to (192)Ir. In addition, the AccuBoost(®) technique has been demonstrated to be a successful non-invasive image-guided breast brachytherapy treatment option. The goal of this project is to evaluate the possibility of utilizing the BEBIG HDR (60)Co system for AccuBoost treatment. These evaluations are performed with Monte Carlo (MC) simulation technique.
  
  
  METHODS
  In this project, the MC calculated dose distributions from HDR (60)Co for various breast sizes have been compared with the simulated data using an HDR (192)Ir source. These calculations were performed using the MCNP5 code. The initial calculations were made with the same applicator dimensions as the ones used with the HDR (192)Ir system (referred here after as standard applicator). The activity of the (60)Co source was selected such that the dose at the center of the breast would be the same as the values from the (192)Ir source. Then, the applicator wall-thickness for the HDR (60)Co system was increased to diminish skin dose to levels received when using the HDR (192)Ir system. With this geometry, dose values to the chest wall and the skin were evaluated. Finally, the impact of a conical attenuator with the modified applicator for the HDR (60)Co system was analyzed.
  
  
  RESULTS
  These investigations demonstrated that loading the (60)Co sources inside the thick-walled applicators created similar dose distributions to those of the (192)Ir source in the standard applicators. However, dose to the chest wall and breast skin with (60)Co source was reduced using the thick-walled applicators relative to the standard applicators. The applicators with conical attenuator reduced the skin dose for both source types.
  
  
  CONCLUSIONS
  The AccuBoost treatment can be performed with the (60)Co source and thick-wall applicators instead of (192)Ir with standard applicators.
authors.affiliation: Radiation Medicine Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Zehtabian
authors.affiliation: Radiation Medicine Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran; Radiation Research Center, Shiraz University, Shiraz, Iran.
authors.forename: Sedigheh
authors.initials: S
authors.lastname: Sina
authors.affiliation: Department of Radiation Oncology, Tufts University School of Medicine, Boston, USA.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Rivard
authors.affiliation: Radiation Medicine Department, School of Mechanical Engineering, Shiraz University, Shiraz, Iran; Comprehensive Cancer Centers of Nevada, Las Vegas, USA.
authors.forename: Ali S
authors.initials: AS
authors.lastname: Meigooni
keywords: AccuBoost; HDR; brachytherapy; breast cancer
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