title: Maximum inspiratory pressure and rapid shallow breathing index as predictors of successful ventilator weaning.
abstract: [Purpose] To investigate the predictive value of maximum inspiratory pressure (MIP) and the rapid shallow breathing index (RSBI) in a ventilator weaning protocol and to evaluate the differences between clinical and surgical patients in the intensive care unit. [Subjects and Methods] Patients aged ≥15 years who underwent orotracheal intubation for mechanical ventilation and who met the criteria of the weaning protocol were included in the study. Receiver operating characteristic (ROC) curves were calculated for the analysis of each index. [Results] Logistic regression analysis was also performed. MIP showed greater sensitivity and specificity [area under the curve (AUC): 0.95 vs. 0.89] and likelihood ratios (LR) (positive(+): 20.85 vs. 9.45; negative(-): 0.07 vs. 0.17) than RSBI in the overall sample (OS) as well as in clinical patients (CP) (AUC: 0.99 vs. 0.90; LR+: 24.66 vs. 7.22; LR-: 0.01 vs. 0.15) and surgical patients (SP) (AUC: 0.99 vs. 0.87; LR+: 9.33 vs. 5.86; LR-: 0.07 vs. 0.14). The logistic regression analysis revealed that both parameters were significantly associated with the weaning success. The MIP showed greater accuracy than the RSBI (OS: 0.93 vs. 0.85; CP: 0.98 vs. 0.87; SP: 0.93 vs. 0.87). [Conclusion] Both parameters are good predictors of successful ventilator weaning.
authors.affiliation: Post Graduation Science Rehabilitation, Nove de Julho University, Brazil.
authors.forename: Umilson Dos Santos
authors.initials: Udos S
authors.lastname: Bien
authors.affiliation: Pulmonary Rehabilitation Center, Federal University of São Paulo, Brazil.
authors.forename: Gerson Fonseca
authors.initials: GF
authors.lastname: Souza
authors.affiliation: Mandaqui Hospital, Brazil.
authors.forename: Elisangela Siqueira
authors.initials: ES
authors.lastname: Campos
authors.affiliation: Post Graduation Science Rehabilitation, Nove de Julho University, Brazil.
authors.forename: Etiene
authors.initials: E
authors.lastname: Farah de Carvalho
authors.affiliation: Post Graduation Science Rehabilitation, Nove de Julho University, Brazil.
authors.forename: Matheus Guedes
authors.initials: MG
authors.lastname: Fernandes
authors.affiliation: Mandaqui Hospital, Brazil.
authors.forename: Ilka
authors.initials: I
authors.lastname: Santoro
authors.affiliation: Post Graduation Science Rehabilitation, Nove de Julho University, Brazil.
authors.forename: Dirceu
authors.initials: D
authors.lastname: Costa
authors.affiliation: Department of Physical Therapy and Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois, USA.
authors.forename: Ross
authors.initials: R
authors.lastname: Arena
authors.affiliation: Post Graduation Science Rehabilitation, Nove de Julho University, Brazil.
authors.forename: Luciana Maria Malosá
authors.initials: LM
authors.lastname: Sampaio
keywords: Mechanical ventilation; Physiological predictor indices; Ventilator weaning
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