title: Learning and Memory Recoveries in a Young Girl Treated with Growth Hormone and Neurorehabilitation.
abstract: Background-To describe the results obtained after treating a non growth hormone-deficient 10-year-old girl who suffered asphyxia during delivery, resulting in important cognitive deficits, with growth hormone (GH) and neurorehabilitation. Methods-GH was administered (mg/day) at doses of 0.5 over three months followed by 0.9, every two weeks over three months, and then alternating 1.2 three days/week and 0.3 two days/week. Neurorehabilitation consisted of daily sessions of neurostimulation, speech therapy, occupational therapy and auditive stimulation. Treatment lasted nine months. Results-Scores obtained in all the areas treated showed that, at discharge, the patient clearly increased her cognitive abilities, memory and language competence index; her intelligence quotient score increased from 51 to 80, and the index of functional independence measure reached a value of 120 over 126 (maximal value). Conclusions-This case suggests that GH administration may play a role in improving cognitive deficits during neurorehabilitation in children with brain damage suffered during delivery. This agrees with the known effects of GH on cognition.
authors.affiliation: Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain. jesus.devesa@usc.es.|Department of Physiology, School of Medicine, University of Santiago de Compostela, Santiago de Compostela 15710, Spain. jesus.devesa@usc.es.
authors.forename: Jesús
authors.initials: J
authors.lastname: Devesa
authors.affiliation: Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain. hortpeque@hotmail.com.
authors.forename: Hortensia
authors.initials: H
authors.lastname: Lema
authors.affiliation: Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain. evazasm@gmail.com.
authors.forename: Eva
authors.initials: E
authors.lastname: Zas
authors.affiliation: Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain. borjamunin@gmail.com.
authors.forename: Borja
authors.initials: B
authors.lastname: Munín
authors.affiliation: Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain. taboada_pernas@hotmail.com.
authors.forename: Pilar
authors.initials: P
authors.lastname: Taboada
authors.affiliation: Medical Centre Foltra, Travesía de Montouto 24, Teo 15886, Spain. pdevesap@foltra.org.
authors.forename: Pablo
authors.initials: P
authors.lastname: Devesa
keywords: brain plasticity; cognitive functions; growth hormone; memory; natal asphyxia; neurorehabilitation
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