title: Antibacterial Activity of Excretions-Secretions from Chrysomya megacephala Against Escherichia coli.
abstract: BACKGROUND
  The blowfly, Chrysomya megacephala, is distributed worldwide. Previous studies found maggot excretions-secretions from other blowfly species inhibited pro-inflammatory response and antimicrobial activity.
  
  
  OBJECTIVE
  This study aimed to test the bactericidal activity of excretions-secretions from C. megacephala larvae.
  
  
  METHODS
  A total of 1,500 3-day-old larvae were used to collect excretions-secretions (ES) modified by the Barnes method. The bactericidal activity ofthe excretions-secretions was test by Pseudomonas aeruginosa, Staphylococcus aureus, and Escherichia coli using suitable liquid culture assay. Scanning electron microscope (SEM) was used to investigate the morphological change ofthe bacteria.
  
  
  RESULTS
  E. coli were significantly inhibited by excretions-secretions from C. megacephala larvae. P. aeruginosa and S. aureus were not found to inhibit growth.
  
  
  CONCLUSIONS
  The excretions-secretions from C. megacephala larvae may have a medical property for the inhibition of bacterial growth.
authors.forename: Tarinee
authors.initials: T
authors.lastname: Chaiwong
authors.forename: Thunyakarn
authors.initials: T
authors.lastname: Srivoramas
authors.forename: Plalakorn
authors.initials: P
authors.lastname: Sebsumran
authors.forename: Marutpong
authors.initials: M
authors.lastname: Panya
authors.forename: Surasak
authors.initials: S
authors.lastname: Wanram
authors.forename: Pawana
authors.initials: P
authors.lastname: Panomket
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D004175:Diptera / Q000737:chemistry* / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects*; D007814:Larva / Q000737:chemistry; D011550:Pseudomonas aeruginosa / Q000187:drug effects*; D013211:Staphylococcus aureus / Q000187:drug effects*
chemical_list: D000900:Anti-Bacterial Agents