title: Placental Mesenchymal Dysplasia.
abstract: Placental mesenchymal dysplasia is a rare, incompletely understood placental stromal lesion, characterized by placentomegaly and striking ectasia and tortuosity of chorionic plate and stem villous vessels. Its prenatal ultrasonographic and gross pathologic features resemble those of a partial mole, but the fetus is typically normal and the placenta has a diploid, chromosomal complement. We discuss the pathologic features and current understanding of the etiopathogenesis of this condition, the supportive immunohistochemical and confirmatory molecular genetic studies important in its diagnosis, and its implications for pregnancy and infant outcomes.
authors.affiliation: Pathology, The University of Alabama at Birmingham, 619 19th Street South, NP 3547, Birmingham, AL 35249-7331, USA; Obstetrics and Gynecology, The University of Alabama at Birmingham, 619 19th Street South, NP 3547, Birmingham, AL 35249-7331, USA. Electronic address: onafp@uab.edu.
authors.forename: Ona Marie
authors.initials: OM
authors.lastname: Faye-Petersen
authors.affiliation: Department of Laboratories, The University of Washington, Seattle Children's Hospital & Regional Medical Center, A6901, 4800 Sand Point Way, NE, Seattle, WA 98105, USA.
authors.forename: Raj P
authors.initials: RP
authors.lastname: Kapur