title: [Effectiveness of the outpatient treatment of the community-acquired pneumonia: systematic review and meta-analysis].
abstract: BACKGROUND
  Community-acquired pneumonia is an important cause of mortality and morbidity worldwide. Therefore, our aim was to assess the efficacy and safety of outpatient treatment of community-acquired pneumonia.
  
  
  METHODS
  We systematically reviewed randomized clinical trials evaluating efficacy and safety of outpatient treatment (OPT) compared with inpatient treatment (IPT) of community-acquired pneumonia in patients without added co-morbidity. Relative Risk (RR) and 95 % confidence interval (95 % CI) were calculated.
  
  
  RESULTS
  From 4088 reviewed articles, two articles were included for meta-analysis, including 2324 patients. One study was conducted in adults, and the other was carried out in pediatric patients. Treatment setting was not significantly associated with treatment failure (RR 0.84 [95% CI 0.68, 1.02]). Death occurred in 6 of 2324 with no difference between the two groups (RR 0.56 [95 % CI 0.12-2.61]). Finally, no differences were seen in hospital readmission between groups (RR 0.82 [95 % CI 0.52-1.30]).
  
  
  CONCLUSIONS
  Evidence shows that treatment setting of community-acquired pneumonia is not statistically associated with treatment failure or mortality.
authors.affiliation: Facultad de Estudios Superiores Zaragoza, Universidad Nacional Autónoma de México, Distrito Federal, México. rivasrodolfo@gmail.com.
authors.forename: Osvaldo Daniel
authors.initials: OD
authors.lastname: Castelán-Martínez
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Hernández-Carbajal
authors.forename: Carlos Eduardo
authors.initials: CE
authors.lastname: Contreras-García
authors.forename: Nancy Guadalupe
authors.initials: NG
authors.lastname: Ojeda-Luna
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Rivas-Ruiz
mesh_terms: D000553:Ambulatory Care; D017714:Community-Acquired Infections / Q000401:mortality / Q000628:therapy; D006801:Humans; D011014:Pneumonia / Q000401:mortality / Q000628:therapy*; D016896:Treatment Outcome
keywords: Meta-analysis as topic; Non-professional home care; Pneumonia; Systematic review