title: Anatomical and clinical aspects of Klinefelter's syndrome.
abstract: Klinefelter's syndrome, the most common sex disorder associated with chromosomal aberrations, is characterized by a plethora of clinical features. Parameters for diagnosis of the syndrome are constantly expanding as new anatomical and hormonal abnormalities are noted, yet Klinefelter's remains underdiagnosed and underreported. This review outlines the key anatomical characteristics associated with the syndrome, which are currently used for clinical diagnosis, or may provide means for improving diagnosis in the future. Clin. Anat. 29:606-619, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Anatomy, University of Otago, Dunedin, 9016, New Zealand.
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Bird
authors.affiliation: Department of Anatomy, University of Otago, Dunedin, 9016, New Zealand.
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Hurren
mesh_terms: D004700:Endocrine System Diseases / Q000209:etiology; D005298:Fertility; D006801:Humans; D007713:Klinefelter Syndrome / Q000150:complications / Q000175:diagnosis / Q000473:pathology* / Q000523:psychology; D008403:Mass Screening; D009140:Musculoskeletal Diseases / Q000209:etiology; D011296:Prenatal Diagnosis; D012727:Sex Characteristics
keywords: Klinefelter's syndrome; anatomy; gonads; polyploidy; sex characteristics; sex chromosome disorders