title: Outcome following Resection of Biliary Cystadenoma: A Single Centre Experience and Literature Review.
abstract: Background. Biliary cystadenomas (BCAs) are rare, benign, potentially malignant cystic lesions of the liver, accounting for less than 5% of cystic liver tumours. We report the outcome following resection of biliary cystadenoma from a single tertiary centre. Methods. Data of patients who had resection of BCA between January 1993 and July 2014 were obtained from liver surgical database. Patient demographics, clinicopathological characteristics, operative data, and postoperative outcome were analysed. Results. 29 patients had surgery for BCA. Male : female ratio was 1 : 28. Clinical presentation was abdominal pain (74%), jaundice (20%), abdominal mass (14%), and deranged liver function tests (3%). Cyst characteristics included septations (48%), wall thickening (31%), wall irregularity (38%), papillary projections (10%), and mural nodule (3%). Surgical procedures included atypical liver resection (52%), left hemihepatectomy (34%), right hemihepatectomy (10%), and left lateral segmentectomy (3%). Median length of stay was 7 (IQ 6.5-8.5) days. Two patients developed postoperative bile leak. No patients had malignancy on final histology. Median follow-up was 13 (IQ 6.5-15.7) years. One patient developed delayed biliary stricture and one died of cholangiocarcinoma 11 years later. Conclusion. Biliary cystadenomas can be resected safely with significantly low morbidity. Malignant transformation and recurrence are rare. Complete surgical resection provides a cure.
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: M
authors.initials: M
authors.lastname: Pitchaimuthu
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: G
authors.initials: G
authors.lastname: Aidoo-Micah
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: C
authors.initials: C
authors.lastname: Coldham
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: R
authors.initials: R
authors.lastname: Sutcliffe
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: J K
authors.initials: JK
authors.lastname: Roberts
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: P
authors.initials: P
authors.lastname: Muiesan
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: J
authors.initials: J
authors.lastname: Isaac
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: D
authors.initials: D
authors.lastname: Mirza
authors.affiliation: Liver and HPB Unit, Queen Elizabeth Hospital, University Hospitals Birmingham NHS Foundation Trust, Birmingham B15 2TH, UK.
authors.forename: R
authors.initials: R
authors.lastname: Marudanayagam
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