title: Reduced germinal center follicular helper T cells but normal follicular regulatory T cells in the tonsils of a patient with a mutation in the PI3KR1 gene.
authors.affiliation: Diabetes Research Institute, San Raffaele Hospital IRCCS, Milan, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Di Fonte
authors.affiliation: Pediatrics Clinic, Institute for Molecular Medicine A. Novicelli, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Baronio
authors.affiliation: Pediatrics Clinic, Institute for Molecular Medicine A. Novicelli, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Plebani
authors.affiliation: Pediatrics Clinic, Institute for Molecular Medicine A. Novicelli, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy.
authors.forename: Vassilios
authors.initials: V
authors.lastname: Lougaris
authors.affiliation: Diabetes Research Institute, San Raffaele Hospital IRCCS, Milan, Italy. Electronic address: fousteri.georgia@hsr.it.
authors.forename: Georgia
authors.initials: G
authors.lastname: Fousteri
mesh_terms: D058543:Class Ia Phosphatidylinositol 3-Kinase; D018858:Germinal Center / Q000276:immunology*; D006801:Humans; D009154:Mutation; D014066:Palatine Tonsil / Q000276:immunology*; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics* / Q000276:immunology*; D006377:T-Lymphocytes, Helper-Inducer / Q000276:immunology*; D050378:T-Lymphocytes, Regulatory / Q000276:immunology
chemical_list: D058543:Class Ia Phosphatidylinositol 3-Kinase; D019869:Phosphatidylinositol 3-Kinases; C588001:PIK3R1 protein, human
keywords: Germinal Centers; Hyper-IgM syndrome; PI3KR1; T follicular helper cells; T follicular regulatory cells; Tonsil