title: Evaluation of structural and functional properties of chitosan-chlorogenic acid complexes.
abstract: The objectives of the present study were to first synthesize chitosan-chlorogenic acid (CA) covalent complex and then compare structural and functional properties between chitosan-CA covalent complex and physical complex. First, chitosan-CA covalent complex was synthesized and its total phenolic content was as high as 276.5 ± 6.2 mg/g. Then structural and functional properties of chitosan-CA covalent and physical complexes were analyzed. The covalent reaction induced formation of both amide and ester bonds in chitosan. Data of X-ray diffraction (XRD) and scanning electron microscopy (SEM) indicated that the complexations of CA changed crystallinity and morphology of chitosan, and covalent complexation induced a larger change of physical structure than physical complexation. In terms of functional properties, chitosan-CA covalent complex exhibited better thermal stability than physical complex in terms of antioxidant activity, and the viscosity of chitosan was significantly increased by covalent modification.
authors.affiliation: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food from Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, People's Republic of China.
authors.forename: Zihao
authors.initials: Z
authors.lastname: Wei
authors.affiliation: Beijing Advanced Innovation Center for Food Nutrition and Human Health, Beijing Laboratory for Food Quality and Safety, Beijing Key Laboratory of Functional Food from Plant Resources, College of Food Science & Nutritional Engineering, China Agricultural University, Beijing 100083, People's Republic of China. Electronic address: gyxcau@126.com.
authors.forename: Yanxiang
authors.initials: Y
authors.lastname: Gao
mesh_terms: D048271:Chitosan / Q000737:chemistry*; D002726:Chlorogenic Acid / Q000138:chemical synthesis / Q000737:chemistry*; D004355:Drug Stability; D016166:Free Radical Scavengers / Q000138:chemical synthesis / Q000737:chemistry; D012212:Rheology; D013696:Temperature
chemical_list: D016166:Free Radical Scavengers; D002726:Chlorogenic Acid; D048271:Chitosan
keywords: Chitosan; Chlorogenic acid; Chlorogenic acid (PubChem CID: 1794427); Cinnamic acid (PubChem CID: 444539); Covalent complex; Gallic acid (PubChem CID: 370)