title: Ocular vestibular evoked myogenic potentials to vertex low frequency vibration as a diagnostic test for superior canal dehiscence.
abstract: OBJECTIVE
  To explore ocular vestibular evoked myogenic potentials (oVEMP) to low-frequency vertex vibration (125 Hz) as a diagnostic test for superior canal dehiscence (SCD) syndrome.
  
  
  METHODS
  The oVEMP using 125 Hz single cycle bone-conducted vertex vibration were tested in 15 patients with unilateral superior canal dehiscence (SCD) syndrome, 15 healthy controls and in 20 patients with unilateral vestibular loss due to vestibular neuritis. Amplitude, amplitude asymmetry ratio, latency and interaural latency difference were parameters of interest.
  
  
  RESULTS
  The oVEMP amplitude was significantly larger in SCD patients when affected sides (53 μVolts) were compared to non-affected (17.2 μVolts) or compared to healthy controls (13.6 μVolts). Amplitude larger than 33.8 μVolts separates effectively the SCD ears from the healthy ones with sensitivity of 87% and specificity of 93%. The other three parameters showed an overlap between affected SCD ears and non-affected as well as between SCD ears and those in the two control groups.
  
  
  CONCLUSIONS
  oVEMP amplitude distinguishes SCD ears from healthy ones using low-frequency vibration stimuli at vertex.
  
  
  CONCLUSIONS
  Amplitude analysis of oVEMP evoked by low-frequency vertex bone vibration stimulation is an additional indicator of SCD syndrome and might serve for diagnosing SCD patients with coexistent conductive middle ear problems.
authors.affiliation: Deparment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden. Electronic address: luca.verrecchia@ki.se.
authors.forename: Luca
authors.initials: L
authors.lastname: Verrecchia
authors.affiliation: Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Magnus
authors.initials: M
authors.lastname: Westin
authors.affiliation: Deparment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Maoli
authors.initials: M
authors.lastname: Duan
authors.affiliation: Deparment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden; Department of Audiology and Neurotology, Karolinska University Hospital, Stockholm, Sweden.
authors.forename: Krister
authors.initials: K
authors.lastname: Brantberg
mesh_terms: D000161:Acoustic Stimulation / Q000379:methods; D000328:Adult; D003955:Diagnostic Tests, Routine / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012665:Semicircular Canals / Q000502:physiology*; D015837:Vestibular Diseases / Q000175:diagnosis* / Q000503:physiopathology; D058585:Vestibular Evoked Myogenic Potentials / Q000502:physiology*; D014724:Vestibular Function Tests / Q000379:methods*; D014722:Vestibule, Labyrinth / Q000502:physiology*; D014732:Vibration; D055815:Young Adult
keywords: BC vibration; Ocular VEMP; SCD; Semicircular canal dehiscence; VEMP; Vertex