title: Interpersonal interactions and empathy modulate perception of threat and defensive responses.
abstract: The defensive peripersonal space (DPPS) is a vital "safety margin" surrounding the body. When a threatening stimulus is delivered inside the DPPS, subcortical defensive responses like the hand-blink reflex (HBR) are adjusted depending on the perceived threat content. In three experiments, we explored whether and how defensive responses are affected by the interpersonal interaction within the DPPS of the face. In Experiment 1, we found that the HBR is enhanced when the threat is brought close to the face not only by one's own stimulated hand, but also by another person's hand, although to a significantly lesser extent. In Experiments 2 and 3, we found that the HBR is also enhanced when the hand of the participant enters the DPPS of another individual, either in egocentric or in allocentric perspective. This enhancement is larger in participants with strong empathic tendency when the other individual is in a third person perspective. These results indicate that interpersonal interactions shape perception of threat and defensive responses. These effects are particularly evident in individuals with greater tendency to having empathic concern to other people.
authors.affiliation: Department of Neuroscience, Physiology and Pharmacology, University College London (UCL),United Kingdom.|SAMBA (SpAtial, Motor &Bodily Awareness) Research Group, Department of Psychology, University of Turin, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Fossataro
authors.affiliation: Department of Neuroscience, Physiology and Pharmacology, University College London (UCL),United Kingdom.
authors.forename: C F
authors.initials: CF
authors.lastname: Sambo
authors.affiliation: SAMBA (SpAtial, Motor &Bodily Awareness) Research Group, Department of Psychology, University of Turin, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Garbarini
authors.affiliation: Department of Neuroscience, Physiology and Pharmacology, University College London (UCL),United Kingdom.
authors.forename: G D
authors.initials: GD
authors.lastname: Iannetti
mesh_terms: D000328:Adult; D001767:Blinking / Q000502:physiology*; D003674:Defense Mechanisms; D004645:Empathy / Q000502:physiology*; D005145:Face / Q000502:physiology; D005260:Female; D006225:Hand / Q000502:physiology; D006801:Humans; D007398:Interpersonal Relations; D008297:Male; D013028:Space Perception; D055815:Young Adult
references.citation: J Neurophysiol. 2012 Feb;107(3):880-9
references.pmid: 22090460
references.citation: Nat Neurosci. 2005 Jul;8(7):955-60
references.pmid: 15937484
references.citation: Neuroimage. 2008 Apr 15;40(3):1419-28
references.pmid: 18291679
references.citation: Curr Biol. 2011 Feb 8;21(3):249-53
references.pmid: 21256015
references.citation: Magn Reson Imaging. 2008 Sep;26(7):1041-54
references.pmid: 18479877
references.citation: J Neurophysiol. 2006 Jan;95(1):205-14
references.pmid: 16162829
references.citation: J Neurosci. 2013 Aug 28;33(35):14225-30
references.pmid: 23986256
references.citation: Soc Neurosci. 2008;3(3-4):250-60
references.pmid: 18792859
references.citation: Neuroimage. 2003 Nov;20(3):1540-51
references.pmid: 14642466
references.citation: Annu Rev Psychol. 2008;59:279-300
references.pmid: 17550343
references.citation: Psychol Sci. 2010 Sep;21(9):1202-7
references.pmid: 20679523
references.citation: J Neurophysiol. 2003 Nov;90(5):3317-29
references.pmid: 12801896
references.citation: Proc Natl Acad Sci U S A. 2011 Jun 28;108 Suppl 2:10910-7
references.pmid: 21690372
references.citation: Neuroscientist. 2014 Apr;20(2):122-35
references.pmid: 24334708
references.citation: Neuropsychologia. 2006;44(13):2621-35
references.pmid: 17128446
references.citation: Science. 2004 Feb 20;303(5661):1157-62
references.pmid: 14976305
references.citation: Curr Biol. 2013 Mar 4;23(5):406-11
references.pmid: 23394831
references.citation: Trends Cogn Sci. 2013 Aug;17(8):371-8
references.pmid: 23796880
references.citation: J Neurophysiol. 1996 Jul;76(1):141-57
references.pmid: 8836215
references.citation: J Neurosci. 2012 Sep 12;32(37):12921-7
references.pmid: 22973016
references.citation: J Neurophysiol. 2016 Jan 1;115(1):218-25
references.pmid: 26510762
references.citation: Neuropsychologia. 2014 Mar;55:128-36
references.pmid: 23988295
references.citation: Proc Natl Acad Sci U S A. 2011 Apr 12;108(15):6270-5
references.pmid: 21444827
references.citation: J Cogn Neurosci. 2010 Jan;22(1):83-96
references.pmid: 19199418