title: A case of giant fetal intracranial capillary hemangioma cured with propranolol.
abstract: Fetal brain tumors are rare. This report describes a giant posterior fossa capillary hemangioma treated with 3 mg/kg/day of propranolol for 6 months. Total regression was confirmed at 1 year, and no additional tumors were observed during the subsequent 2 years. No side effects relating to the use of this drug were detected; thus, the authors believe that propranolol may be useful for treating all intracranial capillary hemangiomas.
authors.affiliation: Department of Neurosurgery, Federal University of São Paulo; and.
authors.forename: Sergio
authors.initials: S
authors.lastname: Cavalheiro
authors.affiliation: Department of Plastic Surgery, Hospital A.C. Camargo, São Paulo, São Paulo, Brazil.
authors.forename: Heloisa Galvão do Amaral
authors.initials: HG
authors.lastname: Campos
authors.affiliation: Department of Neurosurgery, Federal University of São Paulo; and.
authors.forename: Marcos Devanir
authors.initials: MD
authors.lastname: Silva da Costa
mesh_terms: D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000503:physiopathology; D018324:Hemangioma, Capillary / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D006801:Humans; D011247:Pregnancy; D011433:Propranolol / Q000627:therapeutic use*; D055815:Young Adult
chemical_list: D000319:Adrenergic beta-Antagonists; D011433:Propranolol
keywords: MAPK = mitogen-activated protein kinase; US = ultrasonography; apoptosis; capillary hemangioma; fetal brain tumor; hydrocephalus; posterior fossa tumor; propranolol; vascular disorders