title: Clinical evaluations of mineralized collagen in the extraction sites preservation.
abstract: The purpose of this study was to explore the different effects between biomimetic mineralized collagen (MC) and ordinary physically blended hydroxyapatite/collagen (HA/Col) composite in evaluating new bone formation and regenerated bone height in human extraction sockets. Thirty-four patients who cannot retain teeth caused by trauma or decay were randomly selected from Department of Stomatology of Dongzhimen Hospital from December 2013 to December 2014. The patients were randomly divided into two groups. After the operation of tooth extraction, 17 patients were implanted with biomimetic MC (MC group), and other 17 patients were implanted with ordinary physically blended nHA/Col composite (nHA/Col group). X-ray positioning projection by auto-photographing was taken to test the distance between the lowest position and the neighboring CEJm-CEJd immediately, 1 month and 3 months after the operation. The height of new bone formation of the MC group was significantly higher than the nHA/Col group. Biomimetic MC showed better clinical outcomes in the bone formation for extraction site preservation and would have broad application prospect in the field of oral and maxillofacial surgeries.
authors.affiliation: Department of Stomatology, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China;; Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China;
authors.forename: Lu
authors.initials: L
authors.lastname: Feng
authors.affiliation: Second Outpatient Department, General Hospital of Beijing Military Region, Beijing 100125, China;
authors.forename: Liang
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Beijing Allgens Medical Science and Technology Co., Ltd., Beijing 100176, China;
authors.forename: Yun
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Beijing Allgens Medical Science and Technology Co., Ltd., Beijing 100176, China;
authors.forename: Tian-Xi
authors.initials: TX
authors.lastname: Song
authors.affiliation: Beijing Allgens Medical Science and Technology Co., Ltd., Beijing 100176, China;; State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.
authors.forename: Zhi-Ye
authors.initials: ZY
authors.lastname: Qiu
authors.affiliation: State Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing 100084, China.
authors.forename: Xiu-Mei
authors.initials: XM
authors.lastname: Wang
authors.affiliation: Beijing Stomatological Hospital, Capital Medical University, Beijing 100050, China;
authors.forename: Bao-Sheng
authors.initials: BS
authors.lastname: Tan
keywords: biomimetic; bone formation height; extraction site preservation; mineralized collagen
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