title: [CHANGES OF THE HEMOSTASIS SYSTEM IN THE INJURED PERSONS IN FRACTURES OF LONG BONES OF THE LOWER EXTREMITIES].
abstract: The changes of hemostasis in the injured persons, in the lower extremities long bones fracture were analyzed. Complex dynamic investigation of the hemostasis system was conducted preoperatively in 76 injured persons, in whom long bones of the lower extremities fracture have occurred, and in 31--with injury of meniscus. Instrumental diagnostic method--a low-frequency piezoelectric thromboelastography--was applied for investigation of the blood coagulation system. The shift in a system of hemostasis towards hypercoagulation, fibrinolytic and the thrombine activity inhibition, the thrombocytes spontaneous aggregation intensity, duration of formation of a clot fibrinthrombocytic structure; the blood fibrinthrombocytic constanta enhancement, a summary index of the clot retraction and spontaneous lysis reduction were revealed in a hemostasis system before start of the treatment. The hemostasis system disorders in the injured persons may cause thrombohemorrhagic complications, what trusts a necessity for rational choice of preoperative methods of prophylaxis and intensive therapy in a system of hemostasis.
authors.forename: O O
authors.initials: OO
authors.lastname: Tarabrin
authors.forename: I S
authors.initials: IS
authors.lastname: Grichushenko
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001777:Blood Coagulation; D005260:Female; D005337:Fibrin / Q000378:metabolism*; D050723:Fractures, Bone / Q000097:blood* / Q000150:complications / Q000473:pathology; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply / Q000473:pathology; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation; D011300:Preoperative Care; D013916:Thrombelastography; D013917:Thrombin / Q000378:metabolism*; D013927:Thrombosis / Q000097:blood* / Q000150:complications / Q000473:pathology
chemical_list: D005337:Fibrin; D013917:Thrombin