title: [Subcutaneous immunoglobulin. Treatment in chronic inflammatory demyelinating polyradiculo-neuropathy].
abstract: Chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) is an acquired disease that may affect nerve roots and peripheral nerves. Despite its low incidence, diagnosis is particularly important because there are different effective treatments. Human immunoglobulin is one of the mainstays of the treatment. Although there are few studies up to date, subcutaneous immunoglobulin (IgSC) has been proposed as an alternative to intravenous administration with similar efficacy. We present three cases with definite CIDP, classified according to the European Federation of Neurological Societies / Peripheral Nerve, Society (EFNS /PNS) criteria in which was used SCIgG as a treatment after success with the intravenous route. The Overall Neuropathy Limitations Scale (ONLS) was used to estimate the changes in the muscular strength before and after treatment.
authors.affiliation: Instituto de Investigaciones Neurológicas Raúl Carrea (FLENI), Buenos Aires, Argentina. E-mail: mnogues@fleni.org.ar.
authors.forename: Martín A
authors.initials: MA
authors.lastname: Nogués
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Varela
authors.forename: Gisela
authors.initials: G
authors.lastname: Seminario
authors.forename: María C
authors.initials: MC
authors.lastname: Insúa
authors.forename: Liliana
authors.initials: L
authors.lastname: Bezrodnik
mesh_terms: D000328:Adult; D000368:Aged; D006801:Humans; D007136:Immunoglobulins / Q000008:administration & dosage / Q000627:therapeutic use*; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D007279:Injections, Subcutaneous; D008279:Magnetic Resonance Imaging; D008297:Male; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome
chemical_list: D007136:Immunoglobulins; D016756:Immunoglobulins, Intravenous
keywords: chronic inflammatory polyradiculoneuropathy; disability; subcutaneous immunoglobulin