title: [Confocal microscopy for the diagnostics of fungal keratitis].
abstract: Fungal keratitis is a rare but very serious eye disease in industrial nations with a frequency of 1-5 % of all forms of keratitis from microbial causes. We present two patients with keratitis of primary unknown cause. Using confocal microscopy fungal filaments could be identified that partially showed a parallel configuration (like "railway tracks"). Thus, the correct diagnosis can often be made and suitable therapy can be non-invasively initiated even before the results of in vitro cultivation (fungal culture), polymerase chain reaction (PCR) and histological investigations are available.
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Straße 100, Gebäude 22, 66424, Homburg/Saar, Deutschland. loay.daas@uks.eu.
authors.forename: L
authors.initials: L
authors.lastname: Daas
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Straße 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Viestenz
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Straße 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Bischoff
authors.affiliation: Institut für Pathologie, Universitätsklinikum des Saarlandes UKS, Homburg/Saar, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Hasenfus
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Straße 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Seitz
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D015821:Eye Infections, Fungal / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000473:pathology*; D006801:Humans; D007634:Keratitis / Q000000981:diagnostic imaging* / Q000382:microbiology / Q000473:pathology*; D008297:Male; D018613:Microscopy, Confocal / Q000379:methods*; D008875:Middle Aged
keywords: Fungi; Histology; Hyperreflective lines; In vitro cultivation; Polymerase chain reaction
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