title: Light source design for spectral tuning in biomedical imaging.
abstract: We propose an architecture with a remote phosphor-based modular and compact light-emitting diode (LED) light source in a noncontact dermoscope prototype for skin cancer screening. The spectrum and color temperature of the output light can easily and significantly be changed depending on spectral absorption characteristics of the tissues being imaged. The new system has several advantages compared to state-of-the-art phosphor converted ultrabright white LEDs, used in a wide range of medical imaging devices, which have a fixed spectrum and color temperature at a given operating point. In particular, the system can more easily be adapted to the requirements originating from different tissues in the human body, which have wavelength-dependent absorption and reflectivity. This leads to improved contrast for different kinds of imaged tissue components. The concept of such a lighting architecture can be vastly utilized in many other medical imaging devices including endoscopic systems.
authors.affiliation: Leibniz University Hannover , Hannover Centre for Optical Technologies, Nienburger Strasse 17, Hannover 30167, Germany.
authors.forename: Chandrajit
authors.initials: C
authors.lastname: Basu
authors.affiliation: Leibniz University Hannover , Hannover Centre for Optical Technologies, Nienburger Strasse 17, Hannover 30167, Germany.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Schlangen
authors.affiliation: Leibniz University Hannover , Hannover Centre for Optical Technologies, Nienburger Strasse 17, Hannover 30167, Germany.
authors.forename: Merve
authors.initials: M
authors.lastname: Meinhardt-Wollweber
authors.affiliation: Leibniz University Hannover , Hannover Centre for Optical Technologies, Nienburger Strasse 17, Hannover 30167, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Roth
keywords: biomedical imaging; contrast enhancement; digital dermoscopy; remote-phosphor system; skin-cancer screening
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