title: [DIAGNOSTIC VALUE OF COMBINED USE OF COMBINED METHOD OF ENZYME IMMUNOASSAY AND POLYMERASE CHAIN REACTION TO DETECT OF INTRAUTERINE FETAL INFECTION BY PARVOVIRUS B19].
abstract: The combined method of diagnosis parvovirus infection during pregnancy by maternal serum enzyme immunoassay and deoxyribonucleic acid isolation parvovirus B19 polymerase chain reaction in amnniotic fluid and fetal cord blood newborns, can diagnose vertical transmission and anticipate a negative effect on the fetus parvovirus. Lack of maternal IgM antibodies in serum due to parvovirus seroconversion during pregnancy does not exclude the persistence of the virus in the fetus. To analyze the diagnostic value of the method for determining the LHP parvovirus B19 DNA in the amniotic fluid, umbilical cord blood of newborns to determine vertical transmission of parvovirus infection when infected mothers B19 during pregnancy.
authors.forename: N P
authors.initials: NP
authors.lastname: Bondarenko
authors.forename: V P
authors.initials: VP
authors.lastname: Lakatosh
authors.forename: P V
authors.initials: PV
authors.lastname: Lakatosh
authors.forename: O B
authors.initials: OB
authors.lastname: Malanchuk
authors.forename: I V
authors.initials: IV
authors.lastname: Poladich
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000737:chemistry; D000914:Antibodies, Viral / Q000096:biosynthesis*; D004279:DNA, Viral / Q000032:analysis* / Q000235:genetics; D005260:Female; D005312:Fetal Blood / Q000737:chemistry; D005315:Fetal Diseases / Q000175:diagnosis* / Q000276:immunology / Q000401:mortality; D005333:Fetus; D006801:Humans; D007124:Immunoenzyme Techniques; D007075:Immunoglobulin M / Q000096:biosynthesis; D007231:Infant, Newborn; D018445:Infectious Disease Transmission, Vertical; D010322:Parvoviridae Infections / Q000175:diagnosis* / Q000276:immunology / Q000401:mortality / Q000635:transmission; D016732:Parvovirus B19, Human / Q000235:genetics / Q000276:immunology; D016133:Polymerase Chain Reaction; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis* / Q000276:immunology / Q000821:virology; D000069078:Seroconversion; D016019:Survival Analysis
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral; D007075:Immunoglobulin M