title: Pathogenesis of Taenia solium taeniasis and cysticercosis.
abstract: Taenia solium infections (taeniasis/cysticercosis) are a major scourge to most developing countries. Neurocysticercosis, the infection of the human nervous system by the cystic larvae of this parasite, has a protean array of clinical manifestations varying from entirely asymptomatic infections to aggressive, lethal courses. The diversity of clinical manifestations reflects a series of contributing factors which include the number, size and location of the invading parasites, and particularly the inflammatory response of the host. This manuscript reviews the different presentations of T. solium infections in the human host with a focus on the mechanisms or processes responsible for their clinical expression.
authors.affiliation: Cysticercosis Unit, Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.
authors.forename: I
authors.initials: I
authors.lastname: Gonzales
authors.affiliation: Department of Microbiology and Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
authors.forename: J T
authors.initials: JT
authors.lastname: Rivera
authors.affiliation: Cysticercosis Unit, Department of Transmissible Diseases, Instituto Nacional de Ciencias Neurológicas, Lima, Peru.|Department of Microbiology and Center for Global Health, Universidad Peruana Cayetano Heredia, Lima, Peru.
authors.forename: H H
authors.initials: HH
authors.lastname: Garcia
mesh_terms: D000818:Animals; D003552:Cysticercus / Q000472:pathogenicity*; D006801:Humans; D009420:Nervous System / Q000469:parasitology*; D020019:Neurocysticercosis / Q000469:parasitology / Q000473:pathology*; D041201:Taenia solium / Q000472:pathogenicity*; D013622:Taeniasis / Q000469:parasitology / Q000473:pathology*
keywords: Peru; Taenia solium; cysticercosis; epilepsy; neurocysticercosis