title: The expanding landscape of diffusion-weighted MRI in prostate cancer.
abstract: The added value of diffusion-weighted magnetic resonance imaging (DW-MRI) for the detection, localization, and staging of primary prostate cancer has been extensively reported in original studies and meta-analyses. More recently, DW-MRI and related techniques have been used to noninvasively assess prostate cancer aggressiveness and estimate its biological behavior. The present article aims to summarize the potential applications of DW-MRI for noninvasive optimization of pretherapeutic risk assessment, patient management decisions, and evaluation of treatment response.
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
authors.forename: Andreas G
authors.initials: AG
authors.lastname: Wibmer
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
authors.forename: Evis
authors.initials: E
authors.lastname: Sala
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA.
authors.forename: Hedvig
authors.initials: H
authors.lastname: Hricak
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10065, USA. vargasah@mskcc.org.
authors.forename: Hebert Alberto
authors.initials: HA
authors.lastname: Vargas
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D003287:Contrast Media; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D018570:Risk Assessment
chemical_list: D014408:Biomarkers, Tumor; D003287:Contrast Media
keywords: Diffusion-weighted imaging; Magnetic resonance imaging; Prognostic biomarker; Prostate cancer; Risk-assessment; Treatment response
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