title: Negative Tuberculin Skin Test and Prediction of Reversion of QuantiFERON Interferon Gamma Release Assay in US Healthcare Workers.
abstract: QuantiFERON tuberculosis tests (QFT) reverted in (612) 77% of 1,094 low-risk healthcare workers (HCW) testing less than 1.16 IU/mL. Of HCW testing greater than 1.1 IU/mL, 33 (59%) of 56 with negative tuberculin skin tests (TST) reverted vs 8 (6%) of 125 with positive TSTs. Retesting low-risk QFT-positive and TST-negative HCW is prudent.
authors.affiliation: 1Occupational Health Service,Veterans Affairs Health Care System,Palo Alto,California.
authors.forename: Wendy
authors.initials: W
authors.lastname: Thanassi
authors.affiliation: 4War Related Illness and Injury Study Center and Mental Illness Research Education and Clinical Center,Department of Veterans Affairs,Palo Alto,California.
authors.forename: Art
authors.initials: A
authors.lastname: Noda
authors.affiliation: 4War Related Illness and Injury Study Center and Mental Illness Research Education and Clinical Center,Department of Veterans Affairs,Palo Alto,California.
authors.forename: Beatriz
authors.initials: B
authors.lastname: Hernandez
authors.affiliation: 4War Related Illness and Injury Study Center and Mental Illness Research Education and Clinical Center,Department of Veterans Affairs,Palo Alto,California.
authors.forename: Leah
authors.initials: L
authors.lastname: Friedman
authors.affiliation: 6Johns Hopkins University School of Medicine,Baltimore,Maryland.
authors.forename: Susan
authors.initials: S
authors.lastname: Dorman
authors.affiliation: 4War Related Illness and Injury Study Center and Mental Illness Research Education and Clinical Center,Department of Veterans Affairs,Palo Alto,California.
authors.forename: Jerome
authors.initials: J
authors.lastname: Yesavage
mesh_terms: D000328:Adult; D015331:Cohort Studies; D006282:Health Personnel / Q000706:statistics & numerical data*; D006801:Humans; D059425:Interferon-gamma Release Tests / Q000592:standards*; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D012372:ROC Curve; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis*; D014481:United States; D055815:Young Adult