title: Hyperintense perilesional edema in the brain on T1-weighted images: Cavernous malformation or metastatic melanoma? Three case reports and literature review.
abstract: Hyperintense perilesional edema in brain masses on T1-weighted images (T1WI) is an unusual radiological finding. We report three cases showing this particular type of edema, one representing cerebral hemorrhagic cavernous malformation (CCM, cavernoma) and the other two, metastases of melanoma. The association between this sign and cavernoma was recently recognized. On the other hand, in melanotic lesions, the relationship with T1WI-hyperintense perilesional edema has not yet been described. Despite being an infrequent sign, it can considerably narrow the differential diagnosis, which gives it a high value for clinical practice. Moreover, given the high prevalence of the entities that manifest this imaging feature, it can be occasionally noticed.
authors.affiliation: Clinique de Neuroradiologie, Erasme University Hospital, Cliniques Universitaires de Bruxelles, ULB, Belgium Nicolae.Sarbu@erasme.ulb.ac.be.
authors.forename: Nicolae
authors.initials: N
authors.lastname: Sarbu
authors.affiliation: Neuroradiology Department, Hospital Clínic Barcelona, University of Barcelona, Spain.
authors.forename: Teresa
authors.initials: T
authors.lastname: Pujol
authors.affiliation: Neuroradiology Department, Hospital Clínic Barcelona, University of Barcelona, Spain.
authors.forename: Laura
authors.initials: L
authors.lastname: Oleaga
mesh_terms: D000328:Adult; D001929:Brain Edema / Q000209:etiology / Q000473:pathology*; D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000556:secondary*; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D020786:Hemangioma, Cavernous, Central Nervous System / Q000150:complications / Q000473:pathology*; D006801:Humans; D008297:Male; D008545:Melanoma / Q000150:complications / Q000473:pathology* / Q000556:secondary*; D055815:Young Adult
keywords: Cerebral cavernous malformation; cavernoma; hyperintense edema on T1; melanoma
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