title: Comparison of Bioavailability and Biotransformation of Inorganic and Organic Arsenic to Two Marine Fish.
abstract: Dietary uptake could be the primary route of arsenic (As) bioaccumulation in marine fish, but the bioavailability of inorganic and organic As remains elusive. In this study, we investigated the trophic transfer and bioavailability of As in herbivorous rabbitfish Siganus fuscescens and carnivorous seabass Lateolabrax japonicus. Rabbitfish were fed with one artificial diet or three macroalgae, whereas seabass were fed with one artificial diet, one polychaete, or two bivalves for 28 days. The six spiked fresh prey diets contained different proportions of inorganic As [As(III) and As(V)] and organic As compounds [methylarsenate (MMA), dimethylarsenate (DMA), and arsenobetaine (AsB)], and the spiked artificial diet mainly contained As(III) or As(V). We demonstrated that the trophic transfer factors (TTF) of As in both fish were negatively correlated with the concentrations of inorganic As in the diets, while there was no relationship between TTF and the AsB concentrations in the diets. Positive correlation was observed between the accumulated As concentrations and the AsB concentrations in both fish, suggesting that organic As compounds (AsB) were more trophically available than inorganic As. Furthermore, the biotransformation ability of seabass was higher than that in rabbitfish, which resulted in higher As accumulation in seabass than in rabbitfish. Our study demonstrated that different prey with different inorganic/organic As proportions resulted in diverse bioaccumulation of total As in different marine fish.
authors.affiliation: Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou 510301, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Division of Life Science, State Key Laboratory of Marine Pollution, Hong Kong University of Science and Technology (HKUST) , Clearwater Bay, Kowloon, Hong Kong China.
authors.forename: Wen-Xiong
authors.initials: WX
authors.lastname: Wang
authors.affiliation: Key Laboratory of Tropical Marine Bio-resources and Ecology, Guangdong Provincial Key Laboratory of Applied Marine Biology, South China Sea Institute of Oceanology, Chinese Academy of Sciences , Guangzhou 510301, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001151:Arsenic / Q000378:metabolism*; D001492:Bass / Q000378:metabolism*; D001682:Biological Availability; D001711:Biotransformation; D004032:Diet; D007287:Inorganic Chemicals / Q000378:metabolism*; D009928:Organ Specificity; D009930:Organic Chemicals / Q000378:metabolism*; D010473:Perciformes / Q000378:metabolism*
chemical_list: D007287:Inorganic Chemicals; D009930:Organic Chemicals; D001151:Arsenic