title: When to ask male adolescents to provide semen sample for fertility preservation?
abstract: BACKGROUND
  Fertility preservation in adolescents undergoing sterilizing radiation and/or chemotherapy is the standard of care in oncology. The opportunity for patients to provide a semen sample by ejaculation is a critical issue in adolescent fertility preservation.
  
  
  METHODS
  Fifty males with no medical or sexual developmental abnormalities were evaluated. The subjects were screened for evidence of orgasmic, erectile, and ejaculatory dysfunction. A detailed sexual development history was obtained under an Institutional Review Board (IRB)-approved protocol.
  
  
  RESULTS
  Fifty males, aged 18-65 years (mean 39±16.03 years) volunteered to be part of this study. The mean reported age for the onset of puberty was 12.39 years (95% CI, 11.99-12.80 years), 13.59 years (95% CI, 13.05-14.12 years) for the first ejaculation, 12.56 years (95% CI, 11.80-13.32 years) for the start of masturbation, and 17.26 years (95% CI, 16.18-18.33 years) for the first experienced intercourse. Seventy-five percent of the cohort reached puberty by the age of 13.33, experienced masturbation by 14.5, first ejaculated by the age of 14.83, and had intercourse at age of 19.15 years. The first experienced ejaculation fell 1.5 years after the onset of puberty in 80% present of the cohort, and 84% starts masturbation 1.5 years after the onset of puberty. The mean response between the younger and the older subject was not statistical significance.
  
  
  CONCLUSIONS
  It is appropriate to consider a request for semen specimens by masturbation from teenagers at one year and six months after the onset of puberty; the onset age of puberty plus 1.5 years is an important predictor of ejaculation and sample collection for cryopreservation.
authors.affiliation: Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Ali A
authors.initials: AA
authors.lastname: Dabaja
authors.affiliation: Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Wosnitzer
authors.affiliation: Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Alexander
authors.initials: A
authors.lastname: Bolyakov
authors.affiliation: Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Peter N
authors.initials: PN
authors.lastname: Schlegel
authors.affiliation: Department of Urology and Reproductive Medicine, Weill Cornell Medical College, New York, NY 10065, USA.
authors.forename: Darius A
authors.initials: DA
authors.lastname: Paduch
keywords: Fertility preservation; adolescents; cancer management; ejaculation; masturbation; semen collection
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