title: Variants near the HLA complex group 22 gene (HCG22) confer increased susceptibility to late-onset asthma in Japanese populations.
authors.affiliation: Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Yatagai
authors.affiliation: Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.
authors.forename: Tomomitsu
authors.initials: T
authors.lastname: Hirota
authors.affiliation: Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan. Electronic address: t-saka@md.tsukuba.ac.jp.
authors.forename: Tohru
authors.initials: T
authors.lastname: Sakamoto
authors.affiliation: Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: Hideyasu
authors.initials: H
authors.lastname: Yamada
authors.affiliation: Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: Hironori
authors.initials: H
authors.lastname: Masuko
authors.affiliation: Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: Yoshiko
authors.initials: Y
authors.lastname: Kaneko
authors.affiliation: Tsukuba Medical Center, Ibaraki, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Iijima
authors.affiliation: Tsukuba Medical Center, Ibaraki, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Naito
authors.affiliation: Department of Medical Genetics, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: Emiko
authors.initials: E
authors.lastname: Noguchi
authors.affiliation: Laboratory for Respiratory and Allergic Diseases, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.
authors.forename: Mayumi
authors.initials: M
authors.lastname: Tamari
authors.affiliation: Deputy Director, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.
authors.forename: Michiaki
authors.initials: M
authors.lastname: Kubo
authors.affiliation: Laboratory for Statistical Analysis, Center for Integrative Medical Sciences, Institute of Physical and Chemical Research (RIKEN), Kanagawa, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.affiliation: First Department of Medicine, School of Medicine, Hokkaido University, Hokkaido, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Konno
authors.affiliation: First Department of Medicine, School of Medicine, Hokkaido University, Hokkaido, Japan.
authors.forename: Hironi
authors.initials: H
authors.lastname: Makita
authors.affiliation: First Department of Medicine, School of Medicine, Hokkaido University, Hokkaido, Japan.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Nishimura
authors.affiliation: Department of Pathophysiology and Host Defense, Research Institute of Tuberculosis/JATA, Tokyo, Japan.
authors.forename: Minako
authors.initials: M
authors.lastname: Hijikata
authors.affiliation: Department of Pathophysiology and Host Defense, Research Institute of Tuberculosis/JATA, Tokyo, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Keicho
authors.affiliation: Department of Respiratory Medicine, Toho University School of Medicine, Tokyo, Japan.
authors.forename: Sakae
authors.initials: S
authors.lastname: Homma
authors.affiliation: Department of Respiratory Medicine, Tenri Hospital, Nara, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Taguchi
authors.affiliation: Department of Pulmonary Medicine and Oncology, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
authors.forename: Arata
authors.initials: A
authors.lastname: Azuma
authors.affiliation: Fukujuji Hospital, Tokyo, Japan.
authors.forename: Shoji
authors.initials: S
authors.lastname: Kudoh
authors.affiliation: Department of Pulmonary Medicine, Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Hizawa
mesh_terms: D000328:Adult; D017668:Age of Onset; D000483:Alleles; D001249:Asthma / Q000453:epidemiology* / Q000208:ethnology / Q000235:genetics* / Q000276:immunology; D005260:Female; D015870:Gene Expression; D005787:Gene Frequency; D018740:Genetic Heterogeneity; D056426:Genetic Loci; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D006680:HLA Antigens / Q000235:genetics / Q000276:immunology; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009077:Mucins / Q000235:genetics / Q000276:immunology; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide
chemical_list: D006680:HLA Antigens; C000627544:MUC22 protein, human; D009077:Mucins