title: Enantiopure Ferrocene-Based Planar-Chiral Iridacycles: Stereospecific Control of Iridium-Centred Chirality.
abstract: Reaction of [IrCp*Cl2 ]2 with ferrocenylimines (Fc=NAr, Ar=Ph, p-MeOC6 H4 ) results in ferrocene C-H activation and the diastereoselective synthesis of half-sandwich iridacycles of relative configuration Sp *,RIr *. Extension to (S)-2-ferrocenyl-4-(1-methylethyl)oxazoline gave highly diastereoselective control over the new elements of planar chirality and metal-based pseudo-tetrahedral chirality, to give both neutral and cationic half-sandwich iridacycles of absolute configuration Sc ,Sp ,RIr . Substitution reactions proceed with retention of configuration, with the planar chirality controlling the metal-centred chirality through an iron-iridium interaction in the coordinatively unsaturated cationic intermediate.
authors.affiliation: School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
authors.forename: Ross A
authors.initials: RA
authors.lastname: Arthurs
authors.affiliation: School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.|Department of Chemistry, Karakoram International University, University Road, Gilgit-, 15100, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ismail
authors.affiliation: School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
authors.forename: Christopher C
authors.initials: CC
authors.lastname: Prior
authors.affiliation: School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK.
authors.forename: Vasily S
authors.initials: VS
authors.lastname: Oganesyan
authors.affiliation: EPSRC National Crystallography Service, School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.
authors.forename: Peter N
authors.initials: PN
authors.lastname: Horton
authors.affiliation: EPSRC National Crystallography Service, School of Chemistry, University of Southampton, Highfield, Southampton, SO17 1BJ, UK.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Coles
authors.affiliation: School of Chemistry, University of East Anglia, Norwich Research Park, Norwich, NR4 7TJ, UK. Chris.Richards@uea.ac.uk.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Richards
keywords: chirality; enantioselectivity; ferrocene; iridacycle; stereoselectivity