title: Correlation of Clinicohaematological Parameters in Paediatric Dengue: A Retrospective Study.
abstract: Dengue is one of the arthropod-borne (arbo) viral diseases transmitted by female mosquito Aedes aegypti. Dengue fever has a wide spectrum of clinical presentation ranging from flu-like illness to severe complicated stage of dengue hemorrhagic fever leading to mortality. This was a retrospective study conducted in a tertiary care hospital in Coastal Karnataka, South India, to know the correlation between the clinical presentation and haematological parameters in the paediatric cases presented with dengue symptoms. A total of 163 paediatric cases who presented fever and dengue-like illness were included in the study. Of which, 69 were confirmed dengue patients. Critical analysis showed that there was a significant difference in the haematological parameters like total leucocyte count, percent differential leucocyte count, and platelets count, in the erythrocyte sedimentation rate (P < 0.05 to 0.0001). Additionally, when compared to nondengue patients, even the liver function and renal function parameters were significantly deranged (P < 0.05 to 0.0001). Stratification based on NS1, IgG, and IgM showed significant alterations in the haematological, hepatic, and renal parameters. With respect to the treatment a small percentage of patients, that is, 8% (4 patients), required platelet transfusion as their counts went below 20,000/μL. Two patients succumbed to their illness while three required ICU stay.
authors.affiliation: Department of Microbiology, Father Muller Medical College, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Ramakrishna
authors.initials: R
authors.lastname: Pai Jakribettu
authors.affiliation: Department of Microbiology, Father Muller Medical College, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Rekha
authors.initials: R
authors.lastname: Boloor
authors.affiliation: Father Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Andrew
authors.initials: A
authors.lastname: Thaliath
authors.affiliation: Father Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Sharanya
authors.initials: S
authors.lastname: Yesudasan George
authors.affiliation: Father Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Thomas
authors.initials: T
authors.lastname: George
authors.affiliation: Father Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Manoj
authors.initials: M
authors.lastname: Ponadka Rai
authors.affiliation: Father Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Umran
authors.initials: U
authors.lastname: Rafique Sheikh
authors.affiliation: Department of Paediatrics, Father Muller Medical College, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Kadke Shreedhara
authors.initials: KS
authors.lastname: Avabratha
authors.affiliation: Father Muller Research Centre, Kankanady, Mangalore, Karnataka 575002, India.
authors.forename: Manjeshwar Shrinath
authors.initials: MS
authors.lastname: Baliga
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