title: The novel voltammetric method for determination of hesperetin based on a sensitive electrochemical sensor.
abstract: A highly sensitive voltammetric sensor, based on reduced graphene oxide on SWCNTs modified glassy carbon electrode (GCE), was constructed and used for sensitive detection of hesperetin. The electrochemical behavior of hesperetin at this sensor was investigated systematically and a novel voltammetric method for determination of hesperetin was proposed. The redox characters of hesperetin was discussed in detail and a reasonable reaction mechanism was proposed also. As the analytical method, the response currents were linear relationship with the hesperetin concentrations in the range of 5.0 × 10(-8) to 3.0 × 10(-6) mol L-(1), with a detection limit of 2.0 × 10(-8) mol L(-1) (S/N=3). The method was also applied successfully to detect hesperetin in biological samples and Chinese herbal medicine Flos buddlejae with satisfactory results.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Junjun
authors.initials: J
authors.lastname: Wu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China; Department of Environmental Engineering and Chemistry, Luoyang Institute of Science and Technology, Luoyang 471023, PR China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Qinqin
authors.initials: Q
authors.lastname: Wang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China.
authors.forename: Lina
authors.initials: L
authors.lastname: Zou
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, PR China. Electronic address: yebx@zzu.edu.cn.
authors.forename: Baoxian
authors.initials: B
authors.lastname: Ye
mesh_terms: D002138:Calibration; D004563:Electrochemistry / Q000295:instrumentation / Q000379:methods*; D004566:Electrodes; D005898:Glass / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D006569:Hesperidin / Q000032:analysis* / Q000737:chemistry / Q000652:urine; D006801:Humans; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D037742:Nanotubes, Carbon / Q000737:chemistry; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D015203:Reproducibility of Results; D013997:Time Factors
chemical_list: D037742:Nanotubes, Carbon; D010087:Oxides; D006108:Graphite; D006569:Hesperidin; C013015:hesperetin
keywords: Hesperetin; Reduced graphene oxide; SWCNTs