title: The Complete Genome of Brucella Suis 019 Provides Insights on Cross-Species Infection.
abstract: Brucella species are the most important zoonotic pathogens worldwide and cause considerable harm to humans and animals. In this study, we presented the complete genome of B. suis 019 isolated from sheep (ovine) with epididymitis. B. suis 019 has a rough phenotype and can infect sheep, rhesus monkeys and possibly humans. The comparative genome analysis demonstrated that B. suis 019 is closest to the vaccine strain B. suis bv. 1 str. S2. Further analysis associated the rsh gene to the pathogenicity of B. suis 019, and the WbkA gene to the rough phenotype of B. suis 019. The 019 complete genome data was deposited in the GenBank database with ID PRJNA308608.
authors.affiliation: College of Medicine, Shihezi University, Xinjiang 832000, China. a201511281@126.com.|Co-Innovation Center for Zoonotic Infectious Diseases in the western region, Shihezi University, Xinjiang 832000, China. a201511281@126.com.
authors.forename: Yuanzhi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. b201511281@126.com.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.affiliation: College of Life Sciences, Nankai University, Tianjin 300071, China. c201511281@126.com.
authors.forename: Xin
authors.initials: X
authors.lastname: Chen
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. zhanghui@shzu.edu.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: College of Medicine, Shihezi University, Xinjiang 832000, China. d201511281@126.com.|Co-Innovation Center for Zoonotic Infectious Diseases in the western region, Shihezi University, Xinjiang 832000, China. d201511281@126.com.
authors.forename: Fei
authors.initials: F
authors.lastname: Guo
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. e201511281@126.com.
authors.forename: Ke
authors.initials: K
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. f201511281@126.com.
authors.forename: Hanping
authors.initials: H
authors.lastname: Feng
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. g201511281@126.com.
authors.forename: Wenyi
authors.initials: W
authors.lastname: Gu
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. h201511281@126.com.
authors.forename: Changxin
authors.initials: C
authors.lastname: Wu
authors.affiliation: College of Life Sciences, Shihezi University, Xinjiang 832000, China. i201511281@126.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Ma
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. j201511281@126.com.
authors.forename: Tiansen
authors.initials: T
authors.lastname: Li
authors.affiliation: College of Animal Science and Technology, Shihezi University, Xinjiang 832000, China. chenchuangfu@shzu.edu.cn.
authors.forename: Chuangfu
authors.initials: C
authors.lastname: Chen
authors.affiliation: College of Life Sciences, Nankai University, Tianjin 300071, China. gao_shan@mail.nankai.edu.cn.
authors.forename: Shan
authors.initials: S
authors.lastname: Gao
keywords: B. suis 019; Brucella; comparative genomics; complete genome; cross species
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