title: Acquired reactive perforating collagenosis and pseudoporphyric bullous dermatosis in a hemodialysis patient.
abstract: Hemodialysis patients present with a broad spectrum of specific and nonspecific skin disorders, which rarely coexist. We report an exceptional case of a hemodialysis patient that developed acquired reactive perforating collagenosis and pseudoporphyric bullous dermatosis on the basis of common skin disorders which include hyperpigmentation, pruritus, xerosis cutis, and Linsday's nails. Interestingly, our patient presented with two unusual but distinctive cutaneous dermopathies on the background of other commonly seen skin alterations. The patient was successfully treated with allopurinol and N-acetylcysteine. Avoidance of potentially triggering factors such as alcohol, sunlight exposure and certain medication was recommended. Thus, increasing clinical awareness, assiduous investigation and early treatment of skin disorders are required to improve the prognosis and quality of life in this patient population.
authors.affiliation: Department of Nephrology, General Hospital of Pella, Edessa, Greece.
authors.forename: Nikos
authors.initials: N
authors.lastname: Sabanis
authors.affiliation: Department of General Practice and Family Medicine, General Hospital of Pella, Edessa, Greece.
authors.forename: Eleni
authors.initials: E
authors.lastname: Paschou
authors.affiliation: Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Eleni
authors.initials: E
authors.lastname: Gavriilaki
authors.affiliation: Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Asterios
authors.initials: A
authors.lastname: Kalaitzoglou
authors.affiliation: Department of General Surgery, General Hospital of Pella, Edessa, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Papanikolaou
authors.affiliation: Department of Nephrology, General Hospital of Pella, Edessa, Greece.
authors.forename: Sotiris
authors.initials: S
authors.lastname: Vasileiou
authors.affiliation: Department of Pathology, General Hospital Hippokrateion, Thessaloniki, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Amplianitis
keywords: Hemodialysis; acquired reactive perforating collagenosis; pseudoporphyria cutanea tarda; skin disorders