title: Spindle cell oncocytoma of adenohypophysis: Report of a case and immunohistochemical review of literature.
abstract: We present a case of spindle cell oncocytoma (SCO) of the adenohypophysis in a 70-year-old Vietnamese male. The patient was admitted to Cho Ray Hospital after suffering from headache and visual disturbance for 6 months. Clinicians detected a 60×55×45 mm(3) mass located in the suprasellar-sellar region. Histopathologically, the resected tumor was composed of spindle cells with oncocytic appearance. Immunohistochemical examination revealed expression of anti-mitochondria antibody (AMA), vimentin, thyroid transcription factor 1 (TTF-1), epithelial membrane antigen (EMA) and galectin-3. These histologic and immunohistochemical findings are suggestive of SCO.
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan; Department of Pathology, Cho Ray Hospital, Ho Chi Minh City, Viet Nam.
authors.forename: Huy Gia
authors.initials: HG
authors.lastname: Vuong
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Tetsuo
authors.initials: T
authors.lastname: Kondo
authors.affiliation: Department of Pathology, Cho Ray Hospital, Ho Chi Minh City, Viet Nam.
authors.forename: Thong Minh
authors.initials: TM
authors.lastname: Tran
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Oishi
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Tadao
authors.initials: T
authors.lastname: Nakazawa
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Kunio
authors.initials: K
authors.lastname: Mochizuki
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Inoue
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Kazunari
authors.initials: K
authors.lastname: Kasai
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Ippei
authors.initials: I
authors.lastname: Tahara
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan.
authors.forename: Wang
authors.initials: W
authors.lastname: Jieying
authors.affiliation: Department of Pathology, University of Yamanashi, Yamanashi, Japan. Electronic address: rkatoh@yamanashi.ac.jp.
authors.forename: Ryohei
authors.initials: R
authors.lastname: Katoh
mesh_terms: D018249:Adenoma, Oxyphilic / Q000473:pathology*; D000368:Aged; D014408:Biomarkers, Tumor / Q000032:analysis; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D010903:Pituitary Gland, Anterior / Q000473:pathology; D010911:Pituitary Neoplasms / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Immunohistochemistry; Mitochondria; Sellar neoplasms; Spindle cell oncocytoma