title: Advances in the treatment of testicular cancer.
abstract: Germ cell tumors (GCT) are relatively uncommon, accounting for only 1% of male malignancies in the United States. It has become an important oncological disease for several reasons. It is the most common malignancy in young men 15-35 years old. GCTs are among a unique numbers of neoplasms where biochemical markers play a critical role. Finally, it is a model of curable cancer. In this review we discuss cancer epidemiology, genetics, and therapeutic principles. Recent advances in the management of stage I GCT and controversies in the management of post chemotherapy residual mass are presented.
authors.affiliation: 1 Department of Urology, Rabin Medical Centre Beilinson Campus, Petah Tiqwa, Israel ; 2 Sackler Medical School, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
authors.forename: Yaron
authors.initials: Y
authors.lastname: Ehrlich
authors.affiliation: 1 Department of Urology, Rabin Medical Centre Beilinson Campus, Petah Tiqwa, Israel ; 2 Sackler Medical School, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
authors.forename: David
authors.initials: D
authors.lastname: Margel
authors.affiliation: 1 Department of Urology, Rabin Medical Centre Beilinson Campus, Petah Tiqwa, Israel ; 2 Sackler Medical School, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
authors.forename: Marc Alan
authors.initials: MA
authors.lastname: Lubin
authors.affiliation: 1 Department of Urology, Rabin Medical Centre Beilinson Campus, Petah Tiqwa, Israel ; 2 Sackler Medical School, Tel Aviv University, P.O. Box 39040, Tel Aviv 69978, Israel.
authors.forename: Jack
authors.initials: J
authors.lastname: Baniel
keywords: Neoplasms germ cell tumor; chemotherapy; chemotherapy adjuvant; incidence; lymph node excision; neoplasm staging; orchiectomy; patient selection; treatment outcome
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