title: First Characterization of CTX-M-15-Producing Escherichia coli Strains Belonging to Sequence Type (ST) 410, ST224, and ST1284 from Commercial Swine in South America.
abstract: We report for the first time the isolation of CTX-M-15-producingEscherichia colistrains belonging to sequence type (ST) 410, ST224, and ST1284 in commercial swine in Brazil. TheblaCTX-M-15gene was located on F-::A9::B1 and C1::A9::B1 IncF-type plasmids, surrounded by a new genetic context comprising the IS26insertion sequence truncated with the ISEcp1element upstream ofblaCTX-M-15 These results reveal that commercial swine have become a new reservoir of CTX-M-15-producing bacteria in South America.
authors.affiliation: Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
authors.forename: Ketrin C
authors.initials: KC
authors.lastname: Silva
authors.affiliation: Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
authors.forename: Marina
authors.initials: M
authors.lastname: Moreno
authors.affiliation: Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil.
authors.forename: Carlos
authors.initials: C
authors.lastname: Cabrera
authors.affiliation: Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.
authors.forename: Beny
authors.initials: B
authors.lastname: Spira
authors.affiliation: Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil.
authors.forename: Louise
authors.initials: L
authors.lastname: Cerdeira
authors.affiliation: Department of Microbiology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil Department of Clinical Analysis, School of Pharmacy, University of São Paulo, São Paulo, Brazil morenoam@usp.br lincopan@usp.br.
authors.forename: Nilton
authors.identifier: http://orcid.org/0000-0003-0161-5800
authors.initials: N
authors.lastname: Lincopan
authors.affiliation: Department of Preventive Medicine and Animal Health, School of Veterinary Medicine, University of São Paulo, São Paulo, Brazil morenoam@usp.br lincopan@usp.br.
authors.forename: Andrea M
authors.identifier: http://orcid.org/0000-0002-3290-566X
authors.initials: AM
authors.lastname: Moreno
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001938:Brazil / Q000453:epidemiology; D018550:Cephalosporin Resistance; D002511:Cephalosporins / Q000494:pharmacology; D004251:DNA Transposable Elements; D004926:Escherichia coli / Q000187:drug effects / Q000201:enzymology / Q000235:genetics* / Q000302:isolation & purification; D004927:Escherichia coli Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D015870:Gene Expression; D005838:Genotype; D008460:Meat / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D010957:Plasmids / Q000737:chemistry* / Q000378:metabolism; D013552:Swine; D013553:Swine Diseases / Q000453:epidemiology* / Q000382:microbiology; D001618:beta-Lactamases / Q000235:genetics* / Q000378:metabolism
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; D004251:DNA Transposable Elements; C053503:ceftiofur; C473109:beta-lactamase CTX-M-15; D001618:beta-Lactamases
references.citation: Appl Environ Microbiol. 2000 Oct;66(10):4555-8
references.pmid: 11010916
references.citation: J Antimicrob Chemother. 2014 Oct;69(10):2866-9
references.pmid: 24928853
references.citation: Foodborne Pathog Dis. 2009 Apr;6(3):297-304
references.pmid: 19272004
references.citation: Int J Antimicrob Agents. 2011 Apr;37(4):365-7
references.pmid: 21330111
references.citation: J Antimicrob Chemother. 2011 May;66(5):1005-12
references.pmid: 21393166
references.citation: Clin Microbiol Infect. 2011 Jul;17(7):1039-43
references.pmid: 21722255
references.citation: Clin Microbiol Infect. 2011 Aug;17(8):1279-82
references.pmid: 21595794
references.citation: J Antimicrob Chemother. 2011 Sep;66(9):2177
references.pmid: 21705363
references.citation: Foodborne Pathog Dis. 2011 Nov;8(11):1229-34
references.pmid: 21819210
references.citation: Antimicrob Agents Chemother. 2011 Dec;55(12):5493-9
references.pmid: 21930889
references.citation: Clin Microbiol Infect. 2012 Mar;18(3):268-81
references.pmid: 21793988
references.citation: J Antimicrob Chemother. 2012 Aug;67(8):2047-9
references.pmid: 22523317
references.citation: Curr Pharm Des. 2013;19(2):239-49
references.pmid: 22894614
references.citation: PLoS One. 2013;8(6):e66666
references.pmid: 23762496
references.citation: Antimicrob Agents Chemother. 2014;58(2):789-94
references.pmid: 24247146
references.citation: J Antimicrob Chemother. 2014 Oct;69(10):2658-68
references.pmid: 24920651
references.citation: J Microbiol Methods. 2005 Dec;63(3):219-28
references.pmid: 15935499