title: Elaboration of ammonio methacrylate copolymer based spongy cationic particles via double emulsion solvent evaporation process.
abstract: The aim of present work is to investigate systematic study of the preparation of biodegradable particles via double emulsion solvent evaporation technique. The used formation is based on cationic ammonium methacrylate copolymer Eudragit® RS 100, without the use of any stabilizer. The effect of process parameters like ultra turrax® stirring speed and stirring time, ultrasonication time, polymer amount, and volume of outer aqueous phases on the colloidal properties of particles was investigated. All prepared dispersions were characterized in terms of size, size distribution, and electrokinetic properties, and surface morphology was investigated.
authors.affiliation: University of Lyon, UMR 5007, LAGEP- CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France.
authors.forename: Nadiah
authors.initials: N
authors.lastname: Zafar
authors.affiliation: University of Lyon, UMR 5007, LAGEP- CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France.
authors.forename: Ahmad
authors.initials: A
authors.lastname: Bitar
authors.affiliation: University of Lyon, UMR 5007, LAGEP- CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France.
authors.forename: Jean Pierre
authors.initials: JP
authors.lastname: Valour
authors.affiliation: University of Lyon, UMR 5007, LAGEP- CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France.
authors.forename: Hatem
authors.initials: H
authors.lastname: Fessi
authors.affiliation: University of Lyon, UMR 5007, LAGEP- CPE, 43 bd 11 Novembre 1918, F-69622 Villeurbanne, France. Electronic address: elaissari@lagep.univ-lyon1.fr.
authors.forename: Abdelhamid
authors.initials: A
authors.lastname: Elaissari
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D064751:Ammonium Compounds / Q000737:chemistry*; D063566:Biodegradable Plastics / Q000138:chemical synthesis / Q000737:chemistry; D008689:Methacrylates / Q000737:chemistry*
chemical_list: D000180:Acrylic Resins; D064751:Ammonium Compounds; D063566:Biodegradable Plastics; D008689:Methacrylates; C008384:methacrylic acid; C050528:Eudragit RS
keywords: Biodegradable polymer; Double emulsion–diffusion solvent evaporation; Formulation parameters; Ultrasonication