title: Burn unit care of Stevens Johnson syndrome/toxic epidermal necrolysis: A survey.
abstract: Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a systemic disease that can be associated with debilitating acute and chronic complications across multiple organ systems. As patients with acute SJS/TEN are often treated in a burn intensive care unit (BICU), we surveyed burn centers across the United States to determine their approach to the care of these patients. The goal of our study was to identify best practices and possible variations in the care of patients with acute SJS/TEN. We demonstrate that the method of diagnosis, use of systemic therapies, and involvement of subspecialists varied significantly between burn centers. Beyond supportive care provided to every patient, our data highlights a lack of standardization in the acute care of patients with SJS/TEN. A comprehensive guideline for the care of patients with acute SJS/TEN is indicated.
authors.affiliation: University of Michigan Medical School, 1125 Freesia Street, Ann Arbor, MI 48105, USA. Electronic address: hgle@med.umich.edu.
authors.forename: Hong-Gam
authors.initials: HG
authors.lastname: Le
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA. Electronic address: Hajirah_Saeed@meei.harvard.edu.
authors.forename: Hajirah
authors.initials: H
authors.lastname: Saeed
authors.affiliation: Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, 300 Longwood Ave, Boston, MA 02115, USA. Electronic address: Jason.Mantagos@childrens.harvard.edu.
authors.forename: Iason S
authors.initials: IS
authors.lastname: Mantagos
authors.affiliation: Department of Obstetrics and Gynecology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: Caroline.Mitchell@mgh.harvard.edu.
authors.forename: Caroline M
authors.initials: CM
authors.lastname: Mitchell
authors.affiliation: Division of Burns, Department of Surgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: JGoverman@mgh.harvard.edu.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Goverman
authors.affiliation: Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, 243 Charles Street, Boston, MA 02114, USA. Electronic address: James_Chodosh@meei.harvard.edu.
authors.forename: James
authors.initials: J
authors.lastname: Chodosh
mesh_terms: D000208:Acute Disease; D000328:Adult; D002053:Burn Units; D002648:Child; D019033:Delivery of Health Care, Integrated / Q000592:standards*; D005260:Female; D054625:Healthcare Disparities; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D010353:Patient Education as Topic / Q000592:standards; D013262:Stevens-Johnson Syndrome / Q000175:diagnosis / Q000628:therapy*; D014481:United States
keywords: Burn intensive care unit; Stevens-Johnson syndrome; Survey; Toxic epidermal necrolysis