title: Neurotrophic keratitis after transscleral diode laser cyclophotocoagulation.
abstract: OBJECTIVE
  To study the relationship between treatment with diode laser transscleral cyclophotocoagulation and development a neurotrophic keratitis due to the damage of the sensitive corneal innervation.
  
  
  METHODS
  A study was conducted on 5 eyes of 5 patients who were treated with diode laser transscleral cyclophotocoagulation and soon developed neurotrophic ulcers. Personal characteristics of the patients were collected, as well as refraction and risk factors for corneal hypoesthesia, and the parameters of the laser used in the surgery.
  
  
  RESULTS
  It was found that the 5 patients had predisposing factors of corneal hypoesthesia prior to surgery (chronic use of topical beta blockers, surgery with corneal incisions, diabetes mellitus, or corneal dystrophies); however none had developed neurotrophic keratitis until the cyclophotocoagulation was performed. It also showed that 4 of them were highly myopic, and they all were treated with high laser parameters (with an average of 2880 mW for 3s at an average surface of 275°), triggering neurotrophic ulcers between 10 and 35 days after surgery.
  
  
  CONCLUSIONS
  Neurotrophic keratitis is a rare complication that can occur after diode laser transscleral cyclophotocoagulation, secondary to the damage of the long ciliary nerves. The emergence of this disorder can be triggered by the existence of previous risk factors, including high myopia, thus it is important to respect the recommended treatment parameters to prevent the development of this disorder.
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España; Institut Universitari Barraquer, Universidad Autónoma de Barcelona, Barcelona, España. Electronic address: afdezvega@gmail.com.
authors.forename: Á
authors.initials: Á
authors.lastname: Fernández-Vega González
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España; Institut Universitari Barraquer, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: R I
authors.initials: RI
authors.lastname: Barraquer Compte
authors.affiliation: Institut Universitari Barraquer, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: A L
authors.initials: AL
authors.lastname: Cárcamo Martínez
authors.affiliation: Institut Universitari Barraquer, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: M
authors.initials: M
authors.lastname: Torrico Delgadillo
authors.affiliation: Centro de Oftalmología Barraquer, Barcelona, España; Institut Universitari Barraquer, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: M F
authors.initials: MF
authors.lastname: de la Paz
mesh_terms: D000328:Adult; D000368:Aged; D003315:Cornea / Q000294:innervation; D003318:Corneal Opacity / Q000209:etiology; D003320:Corneal Ulcer / Q000209:etiology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000601:surgery; D006801:Humans; D017075:Laser Coagulation / Q000009:adverse effects* / Q000295:instrumentation / Q000379:methods; D054023:Lasers, Semiconductor; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000009:adverse effects; D009882:Ophthalmic Nerve / Q000293:injuries* / Q000528:radiation effects; D011183:Postoperative Complications / Q000209:etiology*; D011832:Radiation Injuries / Q000209:etiology*; D012189:Retrospective Studies
keywords: Ciclofotocoagulación transescleral; Neurotrophic corneal ulcer; Neurotrophic keratitis; Queratitis neurotrófica; Transscleral cyclophotocoagulation; Úlcera corneal neurotrófica