title: Cells With Chromosomal Aberrations Trigger Neoplastic Transformations in Humans.
abstract: Human population cytogenetic studies have revealed that a majority of persons who are prone to developing malignant features possess chromatin bodies termed as marker dots (MDs) measuring nearly 2 to 3 microns. These MDs are seen emanating from certain specific chromosomes, which may be early indicators of neoplastic transformation within cells.
authors.forename: Hit Kishore
authors.initials: HK
authors.lastname: Goswami
mesh_terms: D055908:Bhopal Accidental Release; D001859:Bone Neoplasms / Q000235:genetics; D001943:Breast Neoplasms / Q000235:genetics; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D002843:Chromatin / Q000737:chemistry / Q000235:genetics*; D002869:Chromosome Aberrations / Q000139:chemically induced*; D003110:Colonic Neoplasms / Q000235:genetics; D005260:Female; D005819:Genetic Markers; D006801:Humans
chemical_list: D002843:Chromatin; D005819:Genetic Markers
keywords: MDs; early detection of malignancy by chromosomes; marker dots; specific chromosomal attenuation releases marker dots