title: Pulmonary Sequestration: A 29 Patient Case Series and Review.
abstract: BACKGROUND
  Pulmonary sequestration also known as bronchopulmonary sequestration is a rare disease, with very few case series reviewed in literature. In this study, we review the demographics, presentation, imaging and treatment of pulmonary sequestration in 29 patients from our institution, and provide comparison data from previously published series with an overview of the disease history.
  
  
  METHODS
  Records reviewed for all patients evaluated and treated in our institution with a pathological proven diagnosis of pulmonary sequestration from January 2004 through December 2013. Collected data included demographics, clinical presentation, diagnostic imaging, location of the lesion, type of sequestration, and subsequent treatment.
  
  
  RESULTS
  Of the 29 patients reviewed 8 (28%) were children 0-2 years, 1 adolescent age 17, and 20 (69%) adults 21-70 years with a mean age of 42 among adults. Systemic arterial supply to the sequestered segment was demonstrated with computed tomographic angiography (CTA) in 25 patients (86%). In 19 patients (66%), the sequestered segment was located in the left lower lobe, and 16 (55%) were intralobar.
  
  
  CONCLUSIONS
  Diagnostic delays of pulmonary sequestration were common among the adult population as the presenting symptoms often mimicked other common pulmonary diseases, such as pneumonia and asthma. These findings were consistent among previously published series. CTA was the preferred imaging modality for preoperative planning with high sensitivity and specificity in identifying the lesion.
authors.affiliation: Fellow, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA .
authors.forename: Basheer
authors.initials: B
authors.lastname: Tashtoush
authors.affiliation: Research Fellow, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA .
authors.forename: Roya
authors.initials: R
authors.lastname: Memarpour
authors.affiliation: Fellow, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA .
authors.forename: Jose
authors.initials: J
authors.lastname: Gonzalez
authors.affiliation: Fellow, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA .
authors.forename: James Benjamin
authors.initials: JB
authors.lastname: Gleason
authors.affiliation: Attending Physician, Department of Pulmonary and Critical Care Medicine, Cleveland Clinic , Florida, 2950 Cleveland Clinic Blvd. 33331, Weston, Florida, USA .
authors.forename: Anas
authors.initials: A
authors.lastname: Hadeh
keywords: Bronchopulmonary malformations; Computed tomographic angiography; Congenital lung diseases; Intralobar and extralobar sequestration
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