title: [DAILY INTRAESOPHAGEAL pH-MONITORING IN THE DIAGNOSIS OF THE SEVERITY OF ESOPHAGITIS WITH GASTROESOPHAGEAL REFLUX DISEASE].
abstract: OBJECTIVE
  To identify criteria of pH-grams to diagnose the severity of esophagitis and preneoplastic complications of GERD.
  
  
  METHODS
  63 patients aged from 18 to 70 with A, B, C degree of GERD, according to the Los Angeles classification and 15 patients with intestinal metaplasia of columnar epithelium and leukoplakia of the stratified squamous epithelium of the esophagogastric transition were examined. For daily intraesophageal pH-monitoring "Gastroscan-24", pH probes manufactured by ZAO NPP "Istok- system", Fryazino (Russia) were used. pH-grams were estimated according for indicators DeMeester. Endoscopy was performed by videoesofagogastroscopes of Evis Exera- system--160 and by the tools company "Olympus" (Japan).
  
  
  RESULTS
  5 options of pH-grams were selected, each of them may correspond to some degree of esophagitis, preneoplastic changes of the esophageal mucosa, esophageal and extraesophageal manifestations of GERD.
  
  
  CONCLUSIONS
  Daily pH-monitoring of the esophagus can serve as a screening for the severity of esophagitis, preneoplastic changes of esophagogastric transition, for addressing the need of morphological studies and differential diagnosis of extraesophageal manifestations of GERD.
authors.forename: O B
authors.initials: OB
authors.lastname: Dronova
authors.forename: A A
authors.initials: AA
authors.lastname: Tretyakov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016145:Endoscopy, Digestive System; D004942:Esophagitis, Peptic / Q000145:classification / Q000175:diagnosis / Q000378:metabolism / Q000473:pathology; D004947:Esophagus / Q000378:metabolism / Q000473:pathology; D005260:Female; D005764:Gastroesophageal Reflux / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism / Q000473:pathology; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008297:Male; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods*; D012720:Severity of Illness Index