title: Patterns of Drug Use and Drug-related Hospital Admissions in HIV-Positive and -Negative Gay and Bisexual Men.
abstract: We aimed to compare rates of illicit drug-related hospitalisations in HIV-negative (HIV-ve) (n = 1325) and HIV-positive (HIV+ve) (n = 557) gay and bisexual men (GBM) with rates seen in the general male population and to examine the association between self-reported illicit drug use and drug-related hospitalisation. Participants were asked how often they used a range of illicit drugs in the previous 6 months at annual interviews. Drug-related hospital admissions were defined as hospital admissions for mental or behavioural disorders due to illicit drug use (ICD 10: F11-16, F18, F19), drug poisoning (T40-T45, T50) or toxic effect of gases (T53, T59, T65). Drug-related hospitalisations were 4.8 times higher in the HIV-ve cohort [SIR 4.75 (95 % CI 3.30-6.91)] and 3.5 times higher in the HIV+ve cohort [SIR 3.51 (1.92-5.88)] compared with the general population. Periods of weekly drug use [IRR 1.86 (1.01-3.46)], poly-drug use [IRR 2.17 (1.07-4.38)] and cannabis use [low use-IRR 1.95 (1.01-3.77), high use-IRR 2.58 (1.29-5.16)] were associated with drug-related hospitalisation in both cohorts, as was being a consistently high meth/amphetamine user throughout follow-up [IRR 3.24 (1.07-9.83)] and being an inconsistent or consistent injecting drug user throughout follow-up [IRR 3.94 (1.61-9.66), IRR 4.43(1.04-18.76), respectively]. Other risk factors for drug-related hospitalisation indicated the likelihood of comorbid drug and mental health issues in GBM hospitalised for drug use.
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia. cmoore@kirby.unsw.edu.au.
authors.forename: Cecilia L
authors.initials: CL
authors.lastname: Moore
authors.affiliation: School of Public Health and Community Medicine, University of New South Wales, Sydney, Australia.
authors.forename: Heather F
authors.initials: HF
authors.lastname: Gidding
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: Fengyi
authors.initials: F
authors.lastname: Jin
authors.affiliation: Centre for Social Research in Health, University of New South Wales, Sydney, Australia.
authors.forename: Limin
authors.initials: L
authors.lastname: Mao
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: Kathy
authors.initials: K
authors.lastname: Petoumenos
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: Iryna B
authors.initials: IB
authors.lastname: Zablotska
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: I Mary
authors.initials: IM
authors.lastname: Poynten
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.|Australian Research Centre in Sex, Health and Society, La Trobe University, Melbourne, Australia.
authors.forename: Garrett
authors.initials: G
authors.lastname: Prestage
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: Matthew G
authors.initials: MG
authors.lastname: Law
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: Andrew E
authors.initials: AE
authors.lastname: Grulich
authors.affiliation: The Kirby Institute, University of New South Wales, Wallace Wurth Building, Sydney, NSW, 2052, Australia.
authors.forename: Janaki
authors.initials: J
authors.lastname: Amin
mesh_terms: D000328:Adult; D001315:Australia / Q000453:epidemiology; D001727:Bisexuality / Q000706:statistics & numerical data*; D015331:Cohort Studies; D015897:Comorbidity; D015658:HIV Infections / Q000453:epidemiology / Q000523:psychology*; D018023:HIV Seronegativity; D006679:HIV Seropositivity / Q000453:epidemiology*; D018451:Homosexuality, Male / Q000706:statistics & numerical data*; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D013287:Illicit Drugs; D008297:Male; D008694:Methamphetamine; D008875:Middle Aged; D012307:Risk Factors; D000072339:Sexual and Gender Minorities; D019966:Substance-Related Disorders / Q000453:epidemiology* / Q000523:psychology; D011795:Surveys and Questionnaires
chemical_list: D013287:Illicit Drugs; D008694:Methamphetamine
keywords: Bisexual; Gay; Homosexual; Hospital admission; Illicit drug use; Male
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