title: Arbitrary thresholds of natural variability and severity should not be used to diagnose chronic obstructive pulmonary disease.
authors.affiliation: Dipartimento di Medicina Interna e Specialità Mediche, Università di Genova, Genoa, Italy vito.brusasco@unige.it.
authors.forename: Vito
authors.initials: V
authors.lastname: Brusasco
authors.affiliation: Centro Medico Pneumologico Torino, Turin, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Pellegrino
authors.affiliation: Institute of Occupational and Environmental Medicine, University of Birmingham, Birmingham, UK.
authors.forename: Martin R
authors.initials: MR
authors.lastname: Miller
mesh_terms: D019468:Disease Management; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive; D011788:Quality of Life; D012129:Respiratory Function Tests / Q000379:methods*