title: [Randomised clinical trial to compare two tracheotomy care methods in an Intensive Care Unit].
abstract: BACKGROUND
  Tracheotomy is a common technique in Intensive Care Units (ICU). It is known that nursing care during and after that procedure is directly related to its success, by reducing the possible complications to a minimum, such as the stoma infection, and contributing to a favourable outcome in critical patients.
  
  
  OBJECTIVE
  To compare the use of polyhexanide (PLX) versus saline+povidone iodine (PY) as antiseptics and infection incidence in tracheostomies performed in Intensive Care Units.
  
  
  METHODS
  A 2-year, experimental, randomised, open-label trial carried out in a multidiscipline ICU with 32 beds. The study was approved by the Research Ethics Committee of Principality of Asturias.
  
  
  RESULTS
  The overall infection rate observed for every hundred patients was 1.34 (95% CI; 0.81-2.01), with 1.46 when using PLX and 1.21 for PY (P=.685).
  
  
  CONCLUSIONS
  In spite of the experimental treatment (PLX) was shown to be effective in other types of wounds in our study. No significant differences were found between this technique and the standard one. Since there is no national registry of tracheotomy- associated infections, it is not possible to know whether the rate observed is within the usual parameters.
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: C
authors.initials: C
authors.lastname: Fernández-García
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: A
authors.initials: A
authors.lastname: Alonso-Rodríguez
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: A
authors.initials: A
authors.lastname: Wensell-Fernández
authors.affiliation: Unidad de Apoyo a la Investigación, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: P
authors.initials: P
authors.lastname: Martínez-Camblor
authors.affiliation: Servicio de Medicina Preventiva y Salud Pública, Hospital Universitario Central de Asturias, Oviedo, Asturias, España. Electronic address: belen.sumi@gmail.com.
authors.forename: M B
authors.initials: MB
authors.lastname: Suárez-Mier
authors.affiliation: Federación de Asociaciones de Mayores del Principado de Asturias (FAMPA), Oviedo, Asturias, España.
authors.forename: J
authors.initials: J
authors.lastname: Arenas Fernández
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: B
authors.initials: B
authors.lastname: Linares Gutiérrez
authors.affiliation: Unidad de Cuidados Intensivos, Hospital Universitario Central de Asturias, Oviedo, Asturias, España.
authors.forename: N
authors.initials: N
authors.lastname: Clavero Ballester
mesh_terms: D000891:Anti-Infective Agents, Local / Q000627:therapeutic use; D006801:Humans; D007362:Intensive Care Units; D011206:Povidone-Iodine / Q000627:therapeutic use; D013530:Surgical Wound Infection / Q000188:drug therapy; D014140:Tracheotomy / Q000379:methods*
chemical_list: D000891:Anti-Infective Agents, Local; D011206:Povidone-Iodine
keywords: Biguanidas; Biguanides; Cuidados intensivos; Infección de herida operatoria; Intensive care; Povidona yodada; Povidone-iodine; Surgical wound infection; Tracheotomy; Traqueotomía