title: Evaluation of the Anterior Segment Parameters of the Patients with Scleroderma.
abstract: OBJECTIVE
  To evaluate corneal parameters of scleroderma (SC) patients by Pentacam-HR.
  
  
  METHODS
  Twenty-two eyes of 22 SC patients and 33 eyes of 33 control subjects were enrolled. All participants underwent Pentacam (Pentacam-HR, Oculus, Germany) evaluation. Both SC and control groups were divided into two subgroups as dry eye (DE) (Schirmer test with topical anesthesia (STA) ˂5 mm) and without DE (STA ˃5 mm).
  
  
  RESULTS
  Pachymetric measurements and mean corneal volume (CV) were significantly lower in the SC group than in the control group (p<0.001). Pachymetric measurements and CV of SC patients with DE were significantly lower than all the other subgroups. Control subgroups with or without DE were similar in pachymetric measurements and CV.
  
  
  CONCLUSIONS
  The results suggest that SC patients have thinner corneas compared with control subjects. Additionally, coexistence of DE seems to have an additional impact in the thinning of cornea in SC patients.
authors.affiliation: a School of Medicine, Department of Ophthalmology , Dicle University , Diyarbakir , Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Şahin
authors.affiliation: a School of Medicine, Department of Ophthalmology , Dicle University , Diyarbakir , Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Yüksel
authors.affiliation: a School of Medicine, Department of Ophthalmology , Dicle University , Diyarbakir , Turkey.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Şahin
authors.affiliation: a School of Medicine, Department of Ophthalmology , Dicle University , Diyarbakir , Turkey.
authors.forename: Abdullah Kürşat
authors.initials: AK
authors.lastname: Cingü
authors.affiliation: a School of Medicine, Department of Ophthalmology , Dicle University , Diyarbakir , Turkey.
authors.forename: Fatih Mehmet
authors.initials: FM
authors.lastname: Türkcü
authors.affiliation: b Department of Immunology , Dicle University , Diyarbakir , Turkey.
authors.forename: Savaş
authors.initials: S
authors.lastname: Kaya
authors.affiliation: c Department of Physical Medicine and Rehabilitation , Dicle University , Diyarbakir , Turkey.
authors.forename: Levent
authors.initials: L
authors.lastname: Yazmalar
authors.affiliation: c Department of Physical Medicine and Rehabilitation , Dicle University , Diyarbakir , Turkey.
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Batmaz
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000473:pathology; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000175:diagnosis*; D063171:Corneal Pachymetry; D003941:Diagnostic Techniques, Ophthalmological; D015352:Dry Eye Syndromes / Q000175:diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010781:Photography / Q000379:methods; D012594:Scleroderma, Localized / Q000175:diagnosis*
keywords: Corneal thickness; Scheimpflug imaging; corneal volume; dry eye; inflammatory diseases; scleroderma