title: An Efficient Four-Step Approach Toward Fused Triazino[1,6-a] Quinazolines.
abstract: Herein, we describe a simple, four-step process for the preparation of 1,2,3-triazino[1,6- a]quinazolin-13-ones. This method involves ring-opening, quinazoline-forming condensation, reduction, diazotization accompanied by rapid intramolecular cyclization in the last step afforded the desired products with structurally complex heterocyclic core in excellent to high yields.
authors.forename: Mohammad Hosein
authors.initials: MH
authors.lastname: Sayahi
authors.forename: Shirin
authors.initials: S
authors.lastname: Baghersaei
authors.forename: Fereshteh
authors.initials: F
authors.lastname: Goli
authors.forename: Setareh
authors.initials: S
authors.lastname: Moghimi
authors.forename: Mohammad
authors.initials: M
authors.lastname: Mahdavi
authors.forename: Loghman
authors.initials: L
authors.lastname: Firoozpour
authors.forename: Abbas
authors.initials: A
authors.lastname: Shafiee
authors.affiliation: Department of Medicinal Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences Research Center, Tehran University of Medical Sciences, Tehran, Iran. aforoumadi@yahoo.com.
authors.forename: Alireza
authors.initials: A
authors.lastname: Foroumadi
mesh_terms: D003500:Cyclization; D015394:Molecular Structure; D011799:Quinazolines / Q000138:chemical synthesis* / Q000737:chemistry; D014227:Triazines / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D011799:Quinazolines; D014227:Triazines