title: Maternal Affective Illness in the Perinatal Period and Child Development: Findings on Developmental Timing, Mechanisms, and Intervention.
abstract: Maternal mental illness is one of the most reliable risks for clinically significant child adjustment difficulties. The research literature in this area is very large and broad and dates back decades. In this review, we consider recent research findings on maternal mental illness and child development by focusing particularly on affective illness the perinatal period. We do this because maternal affective illness in the perinatal period is common; recent evidence suggests that pre- and postpartum maternal depression may have lasting effects on child behavioral and somatic health; research in the perinatal period raises acute and compelling questions about mechanisms of transmission and effect; and perinatal-focused interventions may offer distinct advantages for benefitting mother and child and gaining insights into developmental mechanisms. Throughout the review, we attend to the increasing integration of psychological and biological models and the trans-disciplinary approach now required for clinical investigation.
authors.affiliation: Department of Psychiatry, Wynne Center for Family Research, University of Rochester Medical Center, 300 Crittenden Blvd, Rochester, NY, 14642, USA. Tom_OConnor@URMC.Rochester.edu.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: O'Connor
authors.affiliation: Department of Psychiatry, Columbia University Medical Center, 622 West 168th Street, Suite 1540, New York, NY, 10032, USA. CEM31@CUMC.Columbia.edu.|Obstetrics and Gynecology, Columbia University Medical Center, 622 West 168th Street, Suite 1540, New York, NY, 10032, USA. CEM31@CUMC.Columbia.edu.
authors.forename: Catherine
authors.initials: C
authors.lastname: Monk
authors.affiliation: Department of Psychology, University of Rochester, Meliora Hall, Rochester, NY, 14642, USA. ABurke@UR.Rochester.edu.
authors.forename: Anne S
authors.initials: AS
authors.lastname: Burke
mesh_terms: D002648:Child; D002657:Child Development / Q000502:physiology*; D019052:Depression, Postpartum / Q000523:psychology*; D005260:Female; D006801:Humans; D019964:Mood Disorders / Q000523:psychology*; D009034:Mother-Child Relations; D009035:Mothers / Q000523:psychology*; D011247:Pregnancy
keywords: Child development; Developmental programming; Mood disorder; Perinatal
references.citation: J Am Acad Child Adolesc Psychiatry. 2011 May;50(5):460-70
references.pmid: 21515195
references.citation: J Am Acad Child Adolesc Psychiatry. 2010 Jul;49(7):699-707
references.pmid: 20610139
references.citation: Cochrane Database Syst Rev. 2013 Feb 28;(2):CD001134
references.pmid: 23450532
references.citation: Dev Psychopathol. 2007 Spring;19(2):585-602
references.pmid: 17459185
references.citation: J Am Acad Child Adolesc Psychiatry. 2008 Apr;47(4):379-89
references.pmid: 18388766
references.citation: Ann N Y Acad Sci. 2006 Dec;1094:287-91
references.pmid: 17347363
references.citation: Am J Obstet Gynecol. 1967 Jun 1;98 (3):320-35
references.pmid: 5621450
references.citation: PLoS One. 2012;7(3):e33422
references.pmid: 22461893
references.citation: Child Dev. 2004 Jul-Aug;75(4):1085-97
references.pmid: 15260866
references.citation: Early Hum Dev. 1996 Feb 23;44(2):139-51
references.pmid: 8745426
references.citation: Best Pract Res Clin Obstet Gynaecol. 2014 Jan;28(1):61-70
references.pmid: 24269903
references.citation: J Psychosom Obstet Gynaecol. 2010 Jun;31(2):70-82
references.pmid: 20236029
references.citation: Int J Obes Relat Metab Disord. 2001 Aug;25(8):1175-82
references.pmid: 11477502
references.citation: J Child Psychol Psychiatry. 2001 Jul;42(5):623-36
references.pmid: 11464967
references.citation: Dev Psychopathol. 2014 Nov;26(4 Pt 2):1255-66
references.pmid: 25422959
references.citation: Psychoneuroendocrinology. 2013 Sep;38(9):1630-8
references.pmid: 23433748
references.citation: Dev Psychopathol. 2014 May;26(2):393-403
references.pmid: 24621564
references.citation: Obstet Gynecol. 2014 Apr;123(4):857-67
references.pmid: 24785615
references.citation: J Dev Behav Pediatr. 2003 Feb;24(1):32-8
references.pmid: 12584483
references.citation: Dev Psychobiol. 2007 Jul;49(5):474-84
references.pmid: 17577231
references.citation: J Child Psychol Psychiatry. 2014;55(2):99-111
references.pmid: 24127722
references.citation: Child Dev. 2010 Jan-Feb;81(1):115-30
references.pmid: 20331657
references.citation: Dev Psychobiol. 2011 Apr;53(3):221-33
references.pmid: 21400485
references.citation: Psychoneuroendocrinology. 2012 Jun;37(6):818-26
references.pmid: 22001010
references.citation: Biol Psychol. 2008 Jan;77(1):11-9
references.pmid: 17919804
references.citation: Obstet Gynecol. 2011 Aug;118(2 Pt 1):305-12
references.pmid: 21775846
references.citation: Obstet Gynecol. 2005 Nov;106(5 Pt 1):1071-83
references.pmid: 16260528
references.citation: Cochrane Database Syst Rev. 2004 Oct 18;(4):CD001134
references.pmid: 15495008
references.citation: CNS Spectr. 2015 Feb;20(1):48-59
references.pmid: 25263255
references.citation: Br Med J (Clin Res Ed). 1986 May 3;292(6529):1165-7
references.pmid: 3085767
references.citation: PLoS One. 2014 Apr 16;9(4):e94594
references.pmid: 24740157
references.citation: Psychol Med. 2014 Aug;44(11):2309-22
references.pmid: 24495551
references.citation: Science. 2013 Jun 7;340(6137):1215-7
references.pmid: 23599265
references.citation: Child Dev. 2007 Nov-Dec;78(6):1788-98
references.pmid: 17988321
references.citation: Pediatrics. 2012 May;129(5):e1121-8
references.pmid: 22492772
references.citation: Gen Hosp Psychiatry. 2004 Jul-Aug;26(4):289-95
references.pmid: 15234824
references.citation: Psychol Rev. 1999 Jul;106(3):458-90
references.pmid: 10467895
references.citation: Brain Behav Immun. 2013 Aug;32:21-8
references.pmid: 23439080
references.citation: Early Hum Dev. 2012 Jul;88(7):539-46
references.pmid: 22264436
references.citation: Biol Psychiatry. 2010 Jun 1;67(11):1026-32
references.pmid: 20188350
references.citation: Ann N Y Acad Sci. 1999;897:66-75
references.pmid: 10676436