title: High-sensitivity infrared attenuated total reflectance sensors for in situ multicomponent detection of volatile organic compounds in water.
abstract: In situ detection of volatile organic compounds (VOCs) in aqueous environments is imperative for ensuring the quality and safety of water supplies, yet it remains a challenging analytical task. We present a high-sensitivity method for in situ analysis of multicomponent VOCs at low concentrations based on the use of infrared attenuated total reflection (IR-ATR) spectroscopy. This protocol uses a unique ATR waveguide, which comprises a planar silver halide (AgCl(x)Br(1-x)) fiber with cylindrical extensions at both ends to increase the number of internal reflections, and a polymer coating that traps VOCs and excludes water molecules. Depending on the type of VOC and measurement scenario, IR spectra with specific frequency windows, scan times and spectral resolutions are obtained, from which concentration information is derived. This protocol allows simultaneous detection of multiple VOCs at concentrations around 10 p.p.b., and it enables accurate quantification via a single measurement within 5 min without the need for sample collection or sample pretreatment. This IR-ATR sensor technology will be useful for other applications; we have included a procedure for the analysis of protein conformation changes in Supplementary Methods as an example.
authors.affiliation: Chinese Academy of Sciences (CAS) Key Laboratory of Urban Pollutant Conversion, Department of Chemistry, University of Science and Technology of China, Hefei, China.|Jiangsu Key Laboratory of Chemical Pollution Control and Resources Reuse, School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing, China.
authors.forename: Rui
authors.initials: R
authors.lastname: Lu
authors.affiliation: Chinese Academy of Sciences (CAS) Key Laboratory of Urban Pollutant Conversion, Department of Chemistry, University of Science and Technology of China, Hefei, China.
authors.forename: Wen-Wei
authors.initials: WW
authors.lastname: Li
authors.affiliation: Institute of Analytical and Bioanalytical Chemistry, University of Ulm, Ulm, Germany.
authors.forename: Boris
authors.identifier: http://orcid.org/0000-0002-5583-7962
authors.initials: B
authors.lastname: Mizaikoff
authors.affiliation: School of Physics, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Abraham
authors.initials: A
authors.lastname: Katzir
authors.affiliation: Department of Applied Physics, Ariel University Center of Samaria, Ariel, Israel.
authors.forename: Yosef
authors.initials: Y
authors.lastname: Raichlin
authors.affiliation: Chinese Academy of Sciences (CAS) Key Laboratory of Urban Pollutant Conversion, Department of Chemistry, University of Science and Technology of China, Hefei, China.
authors.forename: Guo-Ping
authors.initials: GP
authors.lastname: Sheng
authors.affiliation: Chinese Academy of Sciences (CAS) Key Laboratory of Urban Pollutant Conversion, Department of Chemistry, University of Science and Technology of China, Hefei, China.
authors.forename: Han-Qing
authors.initials: HQ
authors.lastname: Yu
mesh_terms: D002623:Chemistry Techniques, Analytical; D013055:Spectrophotometry, Infrared / Q000379:methods*; D055549:Volatile Organic Compounds / Q000032:analysis*; D014867:Water / Q000737:chemistry*
chemical_list: D055549:Volatile Organic Compounds; D014867:Water
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