title: Silver-Mediated Intermolecular 1,2-Alkylarylation of Styrenes with α-Carbonyl Alkyl Bromides and Indoles.
abstract: A new iron-facilitated silver-mediated radical 1,2-alkylarylation of styrenes with α-carbonyl alkyl bromides and indoles is described, and two new C-C bonds were generated in a single step through a sequence of intermolecular C(sp(3)-Br functionalization and C(sp(2))-H functionalization across the alkenes. This method provides an efficient access to alkylated indoles with broad substrate scope and excellent selectivity.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
authors.forename: Xuan-Hui
authors.initials: XH
authors.lastname: Ouyang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
authors.forename: Ren-Jie
authors.initials: RJ
authors.lastname: Song
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. jhli@hnu.edu.cn.|State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, 730000, China. jhli@hnu.edu.cn.
authors.forename: Jin-Heng
authors.identifier: http://orcid.org/0000-0001-7215-7152
authors.initials: JH
authors.lastname: Li
keywords: C−H functionalization; alkenes; heterocycles; iron; silver