title: Prevalence rate and clinical characteristics of esophageal ectopic sebaceous glands in asymptomatic health screen examinees.
abstract: Ectopic sebaceous glands in the esophagus have rarely been reported and, thus, represent an obscure medical condition. The aim of this study is to identify the prevalence rate and clinical characteristics of this lesion in an asymptomatic population. We prospectively enrolled health screen examinees who underwent esophagogastroduodenoscopy for gastric cancer screening. An esophageal biopsy was performed in the cases in which esophageal ectopic sebaceous glands were suspected. The general characteristics of the examinees were analyzed based on their medical records. A total of 9989 examinees were enrolled, and five examinees were diagnosed with esophageal ectopic sebaceous glands between December 2012 and June 2014. The endoscopic findings of the esophageal ectopic sebaceous glands indicated multiple yellowish patches or papules, which varied in size. The histopathological findings indicated several lobulated sebaceous glands in the squamous epithelium with inflammatory infiltration. The follow-up endoscopic findings indicated that there was no grossly discernible change. In conclusion, esophageal ectopic sebaceous glands are present in 0.05% of asymptomatic subjects. This lesion is thought to be benign and is not related to clinical symptoms. Therefore, esophageal ectopic sebaceous glands do not require further treatment or follow-up, which makes endoscopists free from active efforts for differential diagnosis with other malignant diseases.
authors.affiliation: Department of Family Medicine, Health Promotion Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Areum
authors.initials: A
authors.lastname: Park
authors.affiliation: Department of Gastroenterology Digestive Disease Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Jung-Hyun
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Pathology, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Ayoung
authors.initials: A
authors.lastname: Park
authors.affiliation: Department of Family Medicine, Health Promotion Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Young-Hwan
authors.initials: YH
authors.lastname: Jung
authors.affiliation: Department of Gastroenterology Digestive Disease Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Hyung-Jun
authors.initials: HJ
authors.lastname: Chu
authors.affiliation: Department of Gastroenterology Digestive Disease Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Sang-Su
authors.initials: SS
authors.lastname: Bae
authors.affiliation: Department of Gastroenterology Digestive Disease Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Jeong-Kwon
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Health Promotion Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Won-Yong
authors.initials: WY
authors.lastname: Kim
authors.affiliation: Department of Gastroenterology Digestive Disease Center, Hong Ik Hospital, Seoul, South Korea.
authors.forename: Byung-Kook
authors.initials: BK
authors.lastname: Kim
mesh_terms: D000328:Adult; D058070:Asymptomatic Diseases; D002828:Choristoma / Q000453:epidemiology* / Q000473:pathology; D016145:Endoscopy, Digestive System; D004935:Esophageal Diseases / Q000453:epidemiology* / Q000473:pathology; D004938:Esophageal Neoplasms / Q000453:epidemiology; D004941:Esophagitis / Q000453:epidemiology; D004947:Esophagus / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010212:Papilloma / Q000453:epidemiology; D011127:Polyps / Q000453:epidemiology; D015995:Prevalence; D011446:Prospective Studies; D056910:Republic of Korea / Q000453:epidemiology; D012627:Sebaceous Glands
keywords: endoscopy; esophagus; sebaceous glands