title: Metastasis of breast cancer to renal cancer: report of a rare case.
abstract: Tumor-to-tumor metastasis (TTM) is a rare phenomenon. We present a case of an invasive ductal carcinoma (IDC) of the breast metastasizing to a clear cell renal cell carcinoma (RCC). Breast cancer (BC) metastasis to the RCC is rarely reported, especially in resected kidney tumor. In several cases reported, IDC was the exclusively histologic type of BC metastasized to RCC. It seems that the different molecular type of IDC doesn't affect the metastatic tendencies to RCC. TTM was an indicator of diffuse disease. For any patient with a history of breast cancer, especially with multi-organs metastasis, resection of kidney tumor should be carefully considered.
authors.affiliation: Department of Breast Disease Centre, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences People's Republic of China, Shandong, China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Huo
authors.affiliation: Department of Pathology, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences People's Republic of China, Shandong, China.
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Breast Disease Centre, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences People's Republic of China, Shandong, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Yu
authors.affiliation: Department of Breast Disease Centre, Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences People's Republic of China, Shandong, China.
authors.forename: Wenshu
authors.initials: W
authors.lastname: Zuo
authors.affiliation: Department of Endocrinology, Laiyang Central Hospital Changshan Road, Laiyang, Shandong Province, People's Republic of China, Shandong, China.
authors.forename: Yanfang
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D001943:Breast Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D018270:Carcinoma, Ductal, Breast / Q000737:chemistry / Q000556:secondary* / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000737:chemistry / Q000473:pathology*; D059186:Chemoradiotherapy, Adjuvant; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000737:chemistry / Q000473:pathology* / Q000556:secondary; D015411:Mastectomy, Modified Radical; D009378:Neoplasms, Multiple Primary / Q000737:chemistry / Q000473:pathology* / Q000601:surgery; D009392:Nephrectomy; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor
keywords: Breast cancer; renal cell carcinoma; tumor-to-tumor metastasis
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