title: [Analyze the factors influencing multi-electrode synchronous radiofrequency ablation via switching controller in ex vivo bovine liver].
abstract: OBJECTIVE
  To investigate the effects of different electrode exposed end and different ablated time on lesion size of Cool-tip multi-electrode synchronous radiofrequency ablation via switching controller in ex vivo bovine liver.
  
  
  METHODS
  Twelve combinations of different electrode exposed end (2 cm, 3 cm and 4 cm) were used, and different ablated time (12, 16, 20 and 24 mins) was as experimental parameter. Ablated lesions in longitudinal diameter, transverse diameter and volume were measured. Analyze the factors influencing the lesion size with ANOVA or t test.
  
  
  RESULTS
  The ablated lesions with 3 cm exposed end electrodes were more stable and the spheroidal rate is more close to 1. When ablated 24 mins with 4 cm exposed end electrodes, the longitudinal diameter, transverse diameter and volume were (7.66±0.21), (6.50±0.34) cm and (172±12) cm3, respectively. When the ablated time was constant, the lesions increased with the exposed end length of the electrodes increased. All the data among groups was statistically significant (P<0.01) unless the transverse diameters between 3 and 4 cm exposed end electrode. When the exposed end length of electrodes was constant, the lesions increased with the ablated time increased as a whole. But there was no significant difference in most of the adjacent groups. Only the longitudinal diameters and volumes of 4 cm exposed end electrodes between 20 and 24 min were statistically significant (P<0.05).
  
  
  CONCLUSIONS
  Within the experimental range, the lesion size ablated by Cool-tip multi-electrode synchronous radiofrequency ablation via switching controller increased with the electrode exposed end and ablated time increased. The spheroidal rate of the ablated lesions with 3 cm exposed end is more close to 1.
authors.affiliation: Department of Imaging and Interventional Radiology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in Southern China, Guangzhou 510060, China.
authors.forename: Yanyang
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yangkui
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Email: huangjh@sysucc.org.cn.
authors.forename: Jinhua
authors.initials: J
authors.lastname: Huang
authors.forename: Fei
authors.initials: F
authors.lastname: Gao
authors.forename: Xiongying
authors.initials: X
authors.lastname: Jiang
authors.forename: Tianqi
authors.initials: T
authors.lastname: Zhang
authors.forename: Senmiao
authors.initials: S
authors.lastname: Huang
mesh_terms: D000818:Animals; D017115:Catheter Ablation; D002417:Cattle; D004566:Electrodes; D008099:Liver