title: Malignant tumors of the temporal bone - our experience.
abstract: BACKGROUND
  Malignant tumors of the temporal bone are rare, with an estimated incidence of about 0.8-1.0 per 1,000,000 inhabitants per year. The vast majority of these tumors are squamous cell carcinomas and their treatment is eminently surgical.
  
  
  OBJECTIVE
  This study is an attempt at systematizing the forms of clinical presentation, the therapeutic possibilities, and oncological outcomes of patients with malignant tumors of the temporal bone in a tertiary hospital in Portugal.
  
  
  METHODS
  The authors present a retrospective study of temporal bone tumors treated and followed during otorhinolaryngology consultations between 2004 and 2014. A review of the literature is also included.
  
  
  RESULTS
  Of the 18 patients included in the study, 16 had a primary tumor of the temporal bone, in most cases with squamous cell carcinoma histology. Of these, 13 patients were treated with curative intent that always included the surgical approach. Disease persistence was observed in one patient and local recurrence in five patients, on average 36.8 months after the initial treatment.
  
  
  CONCLUSIONS
  The anatomical complexity of the temporal bone and the close associations with vital structures make it difficult to perform tumor resection with margins of safety and thus, tumor relapses are almost always local. A high level of suspicion is crucial for early diagnosis, and stringent and prolonged follow-up after treatment is essential for diagnosis and timely treatment of recurrances.
authors.affiliation: Centro Hospitalar do Porto, Porto, Portugal. Electronic address: anacostapsilva@gmail.com.
authors.forename: Ana Pereira
authors.initials: AP
authors.lastname: da Silva
authors.affiliation: Instituto Português Oncologia, Porto, Portugal.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Breda
authors.affiliation: Instituto Português Oncologia, Porto, Portugal.
authors.forename: Eurico
authors.initials: E
authors.lastname: Monteiro
mesh_terms: D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D012189:Retrospective Studies; D012888:Skull Neoplasms / Q000175:diagnosis* / Q000601:surgery; D013701:Temporal Bone
keywords: Carcinoma; Osso temporal; Surgical treatment; Temporal bone; Tratamento cirúrgico
references.citation: Curr Opin Otolaryngol Head Neck Surg. 2003 Apr;11(2):107-11
references.pmid: 14515088
references.citation: Neurosurg Clin N Am. 2013 Jan;24(1):97-110
references.pmid: 23174361
references.citation: Otolaryngol Head Neck Surg. 1999 Jul;121(1):62-5
references.pmid: 10388880
references.citation: Acta Otolaryngol. 2010 Aug;130(8):913-6
references.pmid: 20524790
references.citation: Acta Otorhinolaryngol Ital. 2014 Apr;34(2):129-37
references.pmid: 24843224
references.citation: Otolaryngol Head Neck Surg. 2000 Jun;122(6):882-6
references.pmid: 10828803
references.citation: Skull Base. 2010 Nov;20(6):409-14
references.pmid: 21772797
references.citation: Expert Rev Anticancer Ther. 2005 Apr;5(2):391-7
references.pmid: 15877533
references.citation: J Surg Oncol. 2014 Sep;110(4):383-92
references.pmid: 24962035
references.citation: Laryngoscope. 2010 Jun;120(6):1144-51
references.pmid: 20513031
references.citation: J Laryngol Otol. 1992 Oct;106(10):908-10
references.pmid: 1474316
references.citation: J Laryngol Otol. 1993 Aug;107(8):697-702
references.pmid: 8409719
references.citation: Arch Otolaryngol Head Neck Surg. 2001 Jul;127(7):803-7
references.pmid: 11448354
references.citation: Head Neck. 2012 Sep;34(9):1231-9
references.pmid: 21953902
references.citation: J Laryngol Otol. 1999 Nov;113(11):1004-7
references.pmid: 10696381
references.citation: Otolaryngol Clin North Am. 2001 Dec;34(6):1197-218, x
references.pmid: 11728941
references.citation: Laryngoscope. 1983 Jan;93(1):87-105
references.pmid: 6337311
references.citation: Laryngoscope. 2014 May;124(5):1192-8
references.pmid: 24108656
references.citation: Acta Otolaryngol. 2003 Apr;123(3):367-71
references.pmid: 12737292
references.citation: Laryngoscope. 2012 Feb;122(2):393-400
references.pmid: 22252464
references.citation: Acta Otolaryngol. 2004 Dec;124(10):1117-23
references.pmid: 15768802
references.citation: Am J Otol. 2000 Jul;21(4):582-8
references.pmid: 10912706
references.citation: Laryngoscope. 2013 Jan;123(1):244-8
references.pmid: 23008138
references.citation: Laryngoscope. 1990 Oct;100(10 Pt 1):1047-51
references.pmid: 2215034