title: Characterization of a Drinking Water Distribution Pipeline Terminally Colonized by Naegleria fowleri.
abstract: Free-living amoebae, such as Naegleria fowleri, Acanthamoeba spp., and Vermamoeba spp., have been identified as organisms of concern due to their role as hosts for pathogenic bacteria and as agents of human disease. In particular, N. fowleri is known to cause the disease primary amoebic meningoencephalitis (PAM) and can be found in drinking water systems in many countries. Understanding the temporal dynamics in relation to environmental and biological factors is vital for developing management tools for mitigating the risks of PAM. Characterizing drinking water systems in Western Australia with a combination of physical, chemical and biological measurements over the course of a year showed a close association of N. fowleri with free chlorine and distance from treatment over the course of a year. This information can be used to help design optimal management strategies for the control of N. fowleri in drinking-water-distribution systems.
authors: CSIRO Land and Water , Black Mountain Laboratories, P.O. Box 1700, Canberra, ACT, 2601, Australia.
authors: Matthew J
authors: MJ
authors: Morgan
authors: CSIRO Land and Water , Centre for Environment and Life Sciences, Private Bag No. 5, Wembley, Western Australia 6913, Australia.|School of Pathology and Laboratory Medicine and Oceans Institute, University of Western Australia , 35 Stirling Highway, Crawley, Western Australia 6009, Australia.
authors: Samuel
authors: S
authors: Halstrom
authors: CSIRO Land and Water , Centre for Environment and Life Sciences, Private Bag No. 5, Wembley, Western Australia 6913, Australia.
authors: Jason T
authors: JT
authors: Wylie
authors: CSIRO Land and Water , Black Mountain Laboratories, P.O. Box 1700, Canberra, ACT, 2601, Australia.
authors: Tom
authors: T
authors: Walsh
authors: CSIRO Land and Water , Centre for Environment and Life Sciences, Private Bag No. 5, Wembley, Western Australia 6913, Australia.|School of Pathology and Laboratory Medicine and Oceans Institute, University of Western Australia , 35 Stirling Highway, Crawley, Western Australia 6009, Australia.
authors: Anna H
authors: AH
authors: Kaksonen
authors: School of Pathology and Laboratory Medicine and Oceans Institute, University of Western Australia , 35 Stirling Highway, Crawley, Western Australia 6009, Australia.
authors: David
authors: D
authors: Sutton
authors: Water Corporation of Western Australia , 629 Newcastle Street, Leederville, Western Australia 6007, Australia.
authors: Kalan
authors: K
authors: Braun
authors: CSIRO Land and Water , Centre for Environment and Life Sciences, Private Bag No. 5, Wembley, Western Australia 6913, Australia.
authors: Geoffrey J
authors: GJ
authors: Puzon
mesh_terms: D060766:Drinking Water / Q000469:parasitology*; D006801:Humans; D016848:Naegleria fowleri / Q000302:isolation & purification*; D012498:Sanitary Engineering / Q000379:methods*; D013997:Time Factors; D018508:Water Purification / Q000379:methods; D014904:Western Australia
chemical_list: D060766:Drinking Water