title: Fall of the Optical Wall: Freedom from the Tyranny of the Microscope Improves Glioma Risk Stratification.
abstract: A recent study uses an integrated genomic approach to identify biologically defined subgroups of adult diffuse glioma. These results further lay the foundation for a pathological classification scheme for gliomas that incorporates both histology and molecular biomarkers, which appears far more robust than the current scheme, based solely on morphology.
authors: Division of Haematology/Oncology, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada.
authors: Vijay
authors: V
authors: Ramaswamy
authors: Division of Neurosurgery, Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. Electronic address: mdtaylor@sickkids.ca.
authors: Michael D
authors: MD
authors: Taylor
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D001932:Brain Neoplasms / Q000145:classification / Q000378:metabolism / Q000473:pathology*; D005910:Glioma / Q000145:classification / Q000378:metabolism / Q000473:pathology*; D006801:Humans
chemical_list: D014408:Biomarkers, Tumor