title: ANTIGENIC AND GENETIC CHARACTERIZATION OF INFLUENZA B VIRUSES IN 2012 FROM SLUMS, DHAKA, BANGLADESH.
abstract: Nasal and throat swab samples were collected from 400 subjects with influenza-like illness during June to September, 2012 from two heavily crowded slums, Rayerbazar and Hazaribagh, situated southeast of Dhaka, Bangladesh. Forty-one samples were positive for influenza B virus using quantitative RT-PCR, but no influenza A virus was detected. Antigenic characterization revealed that the influenza B viruses were of Yamagata and Victoria lineages, which was confirmed from genetic analysis of hemagglutinin (HA) and neuraminidase (NA) genes. Co-circulation of influenza B viruses of both Yamagata and Victoria lineages in the slums of Dhaka indicates that introduction of a tetravalent vaccine formulation that includes both of these influenza B virus lineages would be more effective in this population.
authors: Mohammad Ariful
authors: MA
authors: Islam
authors: Nazneen
authors: N
authors: Sultana
authors: Firoz
authors: F
authors: Ahmed
authors: M Majibur
authors: MM
authors: Rahman
authors: Sabita Rezwana
authors: SR
authors: Rahman
mesh_terms: D000956:Antigens, Viral; D001459:Bangladesh / Q000453:epidemiology; D002675:Child, Preschool; D005260:Female; D019267:Hemagglutinin Glycoproteins, Influenza Virus / Q000235:genetics*; D006801:Humans; D009981:Influenza B virus / Q000235:genetics* / Q000276:immunology; D007251:Influenza, Human / Q000453:epidemiology / Q000821:virology*; D008297:Male; D009439:Neuraminidase / Q000235:genetics*; D009666:Nose / Q000821:virology; D010614:Pharynx / Q000821:virology; D011204:Poverty Areas; D012367:RNA, Viral / Q000235:genetics*; D020133:Reverse Transcriptase Polymerase Chain Reaction
chemical_list: D000956:Antigens, Viral; D019267:Hemagglutinin Glycoproteins, Influenza Virus; D012367:RNA, Viral; D009439:Neuraminidase