title: Comparison of CT and contrast-enhanced ultrasound findings in hepatic angiomyolipoma with pathological correlations.
abstract: OBJECTIVE
  To compare imaging findings of CT and contrast-enhanced US (CEUS) in hepatic angiomyolipoma (HAML) and investigate their pathological correlations.
  
  
  METHODS
  Imaging findings and preoperative diagnosis of CT and CEUS were retrospectively compared head to head in 46 patients with 54 histologically proven HAMLs. Correlations between imaging features and preoperative diagnosis with pathological types of HAMLs were analyzed.
  
  
  RESULTS
  Fat was detected in 100% of lipomatous type, 84.6% of mixed type, and 7.1% of myomatous type (p = 0.000) of HAML at unenhanced CT. Well-defined hyper-echogenicity was displayed in 100% of lipomatous type, 88.5% of mixed type, 50% of myomatous type, and 66.7% of angiomatous type of HAMLs at unenhanced US. More arterial hyper-enhancement was noted on CEUS (100%) than on CT (73.1%) in mixed type (p = 0.015) and in lipomatous type (90.9% vs. 9.1%, p = 0.000) of HAMLs. Washout was present in more HAMLs on CT than on CEUS (42.6% vs. 18.5%, p = 0.007). Correct preoperative diagnosis was suggested in more HAMLs of myomatous type on CEUS than on CT (42.9% vs. 0%, p = 0.016) but showed no difference in other types of HAMLs.
  
  
  CONCLUSIONS
  There are considerable discrepancies between CT and CEUS findings of HAMLs, and the imaging appearance and preoperative diagnosis of HAMLs on CT and CEUS are significantly affected by pathological types of HAMLs.
authors: Department of Ultrasound, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China. raylee7991@163.com.|Department of Hepato-biliary-Pancreatic Surgery, Southwest Hospital Affiliated to Third Military Medical University, No.30, Gaotangyan Street, Shapingba, Chongqing, 400038, People's Republic of China. raylee7991@163.com.
authors: Rui
authors: R
authors: Li
authors: Department of Ultrasound, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: Chun-Lin
authors: CL
authors: Tang
authors: Department of Radiology, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: Ping
authors: P
authors: Cai
authors: Department of Hepato-biliary-Pancreatic Surgery, Southwest Hospital Affiliated to Third Military Medical University, No.30, Gaotangyan Street, Shapingba, Chongqing, 400038, People's Republic of China.
authors: Kuan-sheng
authors: KS
authors: Ma
authors: Department of Ultrasound, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: Xiao-Hang
authors: XH
authors: Zhang
authors: Department of Radiology, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: Shi-Yi
authors: SY
authors: Ding
authors: Department of Ultrasound, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: Yi
authors: Y
authors: Zhang
authors: Department of Pathology, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: De-Yu
authors: DY
authors: Guo
authors: Department of Pathology, Southwest Hospital Affiliated to Third Military Medical University, Chongqing, People's Republic of China.
authors: Xiao-Chu
authors: XC
authors: Yan
mesh_terms: D000328:Adult; D000368:Aged; D018207:Angiomyolipoma / Q000000981:diagnostic imaging* / Q000473:pathology; D003287:Contrast Media; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed; D014463:Ultrasonography
chemical_list: D003287:Contrast Media
keywords: Computed tomography; Contrast media; Contrast-enhanced ultrasound; Hepatic angiomyolipoma; Pathology