title: Discordant Transient Extreme Hyperleukocytosis in Dichorionic Diamniotic Twins: The Role of the Sex?
abstract: Although a leukemoid reaction is a well-recognized phenomenon in the neonatal intensive care unit, transient extreme hyperleukocytosis in premature infants is rare. The exact mechanism is still unclear and several hypotheses are documented in the literature. In this case report, we describe 2 dichorionic diamniotic premature twins, of whom the 2 girls had extreme hyperleukocytosis, whereas their siblings did not, emphasizing the potentially important role of the sex in this phenomena.
authors: Department of Neonatology, Isala, Zwolle, The Netherlands.
authors: Merel
authors: M
authors: Boesveld
authors: Marieke A C
authors: MA
authors: Hemels
mesh_terms: D000305:Adrenal Cortex Hormones / Q000008:administration & dosage; D002821:Chorioamnionitis; D005260:Female; D006801:Humans; D062071:Infant, Extremely Premature / Q000097:blood*; D007231:Infant, Newborn; D007964:Leukocytosis / Q000097:blood*; D008297:Male; D011247:Pregnancy; D047928:Premature Birth / Q000097:blood; D012727:Sex Characteristics; D014429:Twins, Dizygotic
chemical_list: D000305:Adrenal Cortex Hormones