title: Methods to measure peripheral and central sensitization using quantitative sensory testing: A focus on individuals with low back pain.
abstract: Quantitative sensory testing can be used to assess peripheral and central sensitization; important factors that contribute to the individual's experience of pain and disability. Many studies use quantitative sensory testing in patients with low back pain to detect alterations in pain sensitivity, however, because investigators employ different protocols, interpretation of findings across studies can become problematic. The purpose of this article is to propose a standardized method of testing peripheral and central pain sensitization in patients with low back pain. Video clips are provided to demonstrate correct procedures for measuring the response to experimental pain using mechanical, thermal and pressure modalities. As nurse researchers and clinicians increase utilization of quantitative sensory testing to examine pain phenotypes, it is anticipated that more personalized methods for monitoring the trajectory of low back pain and response to treatment will improve outcomes for this patient population.
authors: Virginia Commonwealth University School of Nursing, Richmond, VA, USA 23298-0567. Electronic address: astarkweathe@vcu.edu.
authors: Angela R
authors: AR
authors: Starkweather
authors: Virginia Commonwealth University School of Nursing, Richmond, VA, USA 23298-0567.
authors: Amy
authors: A
authors: Heineman
authors: Virginia Commonwealth University School of Nursing, Richmond, VA, USA 23298-0567.
authors: Shannon
authors: S
authors: Storey
authors: Virginia Commonwealth University School of Nursing, Richmond, VA, USA 23298-0567.
authors: Gil
authors: G
authors: Rubia
authors: University of Florida College of Nursing, Gainesville, FL, USA 32610-0197.
authors: Debra E
authors: DE
authors: Lyon
authors: University of Maryland School of Nursing, Baltimore, MD, USA 21201.
authors: Joel
authors: J
authors: Greenspan
authors: University of Maryland School of Nursing, Baltimore, MD, USA 21201.
authors: Susan G
authors: SG
authors: Dorsey
mesh_terms: D059333:Central Nervous System Sensitization / Q000502:physiology*; D006801:Humans; D017116:Low Back Pain / Q000503:physiopathology*; D010525:Peripheral Nerves / Q000503:physiopathology*; D014741:Video Recording
keywords: Central sensitization; Chronic low back pain; Low back pain; Pain sensitization; Peripheral sensitization; Quantitative sensory testing