title: Endoscopic Versus Microscopic Approach in Pituitary Surgery.
abstract: The objective of this study is to compare the efficacy and complications of endoscopic and microscopic transsphenoidal surgery in the treatment of pituitary adenomas. A total of 105 follow-up cases including 60 in endoscopic surgery and 45 in microscopic surgery were treated in our hospital between January 2012 and November 2014. The endoscopic approach had a higher rate of gross tumor removal (81.7% versus 62.2%, P < 0.05) as well as a lower rate of postoperative complications (18.3% versus 35.6%, P < 0.05) than that in the microscopic group. There was no significant difference in the rates of visual improvement and cerebrospinal fluid leak between endoscopic group and microscopic group (P > 0.05). The length of the operation was longer (175 ± 25 minutes versus 110 ± 17 minutes, P < 0.05) but the postoperative hospital stay was significantly shorter (5.1 ± 0.7 versus 7.8 ± 0.8 days, P < 0.05) for the endoscopic surgery group compared with microscopic surgery group. Endoscopic approach provides a wide surgical field and broad lateral vision making easier distinction of tumor tissue. The results of this study support the safety and short-term efficacy of endoscopic pituitary surgery.
authors: *Department of Neurosurgery, Ren Ji Hospital, School of Medicine, Shanghai Jiao Tong University †Department of Neurosurgery, Shanghai Tenth People's Hospital, Tongji University School of Medicine, Shanghai, China.
authors: Yang
authors: Y
authors: Gao
authors: Hui
authors: H
authors: Zheng
authors: Siyi
authors: S
authors: Xu
authors: Yan
authors: Y
authors: Zheng
authors: Yong
authors: Y
authors: Wang
authors: Jiyao
authors: J
authors: Jiang
authors: Chunlong
authors: C
authors: Zhong
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007016:Hypophysectomy / Q000379:methods*; D007902:Length of Stay; D008297:Male; D008866:Microsurgery / Q000379:methods*; D008875:Middle Aged; D061646:Operative Time; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology*; D016896:Treatment Outcome; D055815:Young Adult