title: State of diagnostic quandary solved by modern technology: a rare case of Madelung's disease.
abstract: Madelung's disease is a neglected metabolic disease characterised by generalised multiple fatty tissue deposits. A 64-year-old Caucasian woman presented with generalised weakness and symptomatic hypoglycaemia with altered mental status. Physical examination showed very distinct physical characteristics with multiple lumps distributed over the upper body. Her neurological symptoms were solved by giving intravenous glucose and optimisation of medical treatment. Even though she had unique characteristics of Madelung's disease, many physicians, on several occasions, failed to recognise her 'hidden diagnosis'. This diagnostic uncertainty was able to be solved by searching the Internet for similar clinical features and images. This case demonstrates characteristics and unique features of a rare disease that can be seen in a female patient even though it is mostly found in males.
authors: Department of Internal Medicine, Brooklyn Hospital Center, Brooklyn, New York, USA.
authors: Htoo
authors: H
authors: Kyaw
authors: Department of Internal Medicine, Brooklyn Hospital Center, Brooklyn, New York, USA.
authors: Michael
authors: M
authors: Grillo
authors: Department of Internal Medicine, Brooklyn Hospital Center, Brooklyn, New York, USA.
authors: Aung Naing
authors: AN
authors: Lin
authors: Department of Internal Medicine, Brooklyn Hospital Center, Brooklyn, New York, USA.
authors: David A
authors: DA
authors: Kapp
mesh_terms: D000273:Adipose Tissue / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D007003:Hypoglycemia / Q000209:etiology; D008069:Lipomatosis, Multiple Symmetrical / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D008875:Middle Aged; D018908:Muscle Weakness / Q000209:etiology; D013131:Spine / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed