title: [Physicochemical incompatibilities of injectable drugs].
abstract: The physicochemical interactions of injectable drugs administered through a Y-site injection port are little known phenomena, poorly documented but very frequent. Physicochemical incompatibility is defined as a chemical reaction between two injectable drugs which come into contact with each other. This chemical reaction may be visible on a macroscopic level or completely invisible. The risks of these interactions are not harmless, ranging from inefficacy to the toxicity of the newly-formed compounds.
authors: Hôpital d'instruction des Armées Legouest, 27, avenue de Plantières, 57070 Metz, France. Electronic address: christelle.merlin@santarm.fr.
authors: Christelle
authors: C
authors: Hofmann
authors: Hôpital d'instruction des Armées Legouest, 27, avenue de Plantières, 57070 Metz, France.
authors: Médéric
authors: M
authors: Rouault
authors: Hôpital d'instruction des Armées Legouest, 27, avenue de Plantières, 57070 Metz, France.
authors: Jérémy
authors: J
authors: Cailleteau
mesh_terms: D004347:Drug Interactions; D006801:Humans; D007267:Injections
keywords: catheter; cathéter; dilution; drug interaction; incompatibilité physicochimique; injectable drug; interaction médicamenteuse; médicament injectable; perfusion; physicochemical incompatibility