title: A history of the DNA repair and mutagenesis field: The discovery of base excision repair.
abstract: This article reviews the early history of the discovery of an DNA repair pathway designated as base excision repair (BER), since in contrast to the enzyme-catalyzed removal of damaged bases from DNA as nucleotides [called nucleotide excision repair (NER)], BER involves the removal of damaged or inappropriate bases, such as the presence of uracil instead of thymine, from DNA as free bases.
authors: Department of Pathology, University of Texas, Southwestern Medical Center at Dallas, Dallas, TX 75390, United States.
authors: Errol C
authors: EC
authors: Friedberg
mesh_terms: D001419:Bacteria / Q000378:metabolism; D001671:Biochemistry / Q000266:history*; D004247:DNA / Q000266:history / Q000378:metabolism; D004260:DNA Repair; D045643:DNA Repair Enzymes; D056890:Eukaryota / Q000378:metabolism; D049673:History, 20th Century; D049674:History, 21st Century; D016296:Mutagenesis; D009613:Nobel Prize
chemical_list: D004247:DNA; D045643:DNA Repair Enzymes