title: [Aseptic cutaneous breast abscesses associated with ulcerative colitis].
abstract: BACKGROUND
  Inflammatory bowel diseases are associated with a broad range of cutaneous lesions. Herein we report the first case of aseptic skin abscesses associated with ulcerative colitis.
  
  
  METHODS
  Since March 2008, a 40-year-old woman presented with bilateral mammary abscesses, relapsing despite repeated antibiotic treatment. She was followed for ulcerative colitis diagnosed in 2011 by means of a rectal biopsy. Despite four surgical procedures, there was no improvement in her mammary abscesses and bilateral mastectomy was then proposed because of the persistent symptoms. Her general state of health remained stable. Clinically, there were bilateral inflammatory nodes with fistulae and pus. These lesions were extremely painful. Mild inflammatory syndrome was noted, but the immunological tests revealed nothing of note. Bacteriological, parasitological and mycological tests on biopsy specimens were negative. Histological examination of a surgical biopsy revealed lymphoplasmacytic infiltration of the dermis and subcutis with altered polymorphonuclear cells and epithelioid granuloma. The CT-scan showed no other remote lesions. The final diagnosis was cutaneous aseptic abscess syndrome associated with ulcerative colitis. Colchicine 1mg/day was initiated and resulted in regression of the skin lesions, with complete remission at one year of follow-up.
  
  
  CONCLUSIONS
  Aseptic abscess syndrome must be considered in the event of recurrent aseptic cutaneous abscesses which may be associated with inflammatory bowel disease. Surgery should be avoided and treatment should be based on suitable drug therapy.
authors: Service de dermatologie, hôpital Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France.
authors: C
authors: C
authors: Sallé de Chou
authors: Université Paris Est Créteil (UPEC), faculté de médecine, 8, rue du Général-Sarrail, 94000 Créteil, France.
authors: N
authors: N
authors: Ortonne
authors: Inserm, centre d'investigation clinique 006, 94010 Créteil cedex, France.
authors: M
authors: M
authors: Hivelin
authors: Service de dermatologie, hôpital Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France.
authors: P
authors: P
authors: Wolkenstein
authors: Service de dermatologie, hôpital Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France; Université Paris Est Créteil (UPEC), faculté de médecine, 8, rue du Général-Sarrail, 94000 Créteil, France; Inserm, centre d'investigation clinique 006, 94010 Créteil cedex, France.
authors: O
authors: O
authors: Chosidow
authors: Service de dermatologie, hôpital Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil cedex, France. Electronic address: laurence.allanore@hmn.aphp.fr.
authors: L
authors: L
authors: Valeyrie-Allanore
mesh_terms: D000038:Abscess / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D000328:Adult; D001941:Breast Diseases / Q000209:etiology* / Q000473:pathology / Q000601:surgery; D003093:Colitis, Ulcerative / Q000150:complications*; D005260:Female; D006099:Granuloma / Q000473:pathology; D006801:Humans; D008264:Macrophages / Q000473:pathology; D008408:Mastectomy
keywords: Abcès aseptiques; Aseptic skin abscesses; Breast; Dermatose neutrophilique; Neutrophilic dermatosis; Rectocolite hémorragique; Seins; Ulcerative colitis