title: Clinical prospective evaluation of zirconia-based three-unit posterior fixed dental prostheses: Up-to ten-year results.
abstract: OBJECTIVE
  Only a few studies exist, which assess the clinical long-term behavior of all-ceramic FDPs in the posterior region. The aim of the present prospective clinical study was to evaluate the clinical performance of posterior three-unit FDPs manufactured from Y-TZP after a service period up to 10 years.
  
  
  METHODS
  55 patients received 59 three-unit FDPs in the posterior region of the maxilla or mandible. Abutment teeth were prepared and full-arch impressions were taken. Definitive casts were fabricated and optically scanned. Frameworks were fabricated with computer-aided design (CAD) and manufacturing (CAM) technology. Y-TZP frameworks were veneered and adhesively luted to the abutment teeth. Baseline and follow-up examinations (service time: ≥ 48 months) were recorded by applying modified United States Public Health Services (USPHS) rating criteria. Cumulative survival rate was analyzed with Kaplan-Meier. Percentage of biological and technical complication was calculated.
  
  
  RESULTS
  Fifty-three patients with 57 FDPs attended the last follow-up visit and a mean observation period of the remaining was 6.3 ± 1.9 years was calculated. Biological complications occurred in 17.5%, technical complications in 28% of the FDPs. The 10-year cumulative survival rate amounted 85.0%. Three FDPs failed to survive, two due to a root fracture of the abutment tooth and one due to secondary caries.
  
  
  CONCLUSIONS
  Three-unit FDPs made from Y-TZP, veneered with ceramic offer a treatment option with a high rate of chipping. However, the manufacturing processes nowadays are modified in order to avoid this complication.
  
  
  CONCLUSIONS
  The results of the present investigation suggest that three-unit Y-TZP posterior FDPs may are a possible treatment option. However, a high rate of chipping can be expected.
authors: Clinic of Preventive Dentistry, Periodontology and Cariology, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland. Electronic address: alexis.ioannidis@zzm.uzh.ch.
authors: Alexis
authors: A
authors: Ioannidis
authors: Clinic of Preventive Dentistry, Periodontology and Cariology, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, 8032 Zurich, Switzerland. Electronic address: andreas.bindl@zzm.uzh.ch.
authors: Andreas
authors: A
authors: Bindl
mesh_terms: D000328:Adult; D000368:Aged; D002516:Ceramics / Q000737:chemistry*; D003731:Dental Caries / Q000628:therapy; D018772:Dental Marginal Adaptation; D003776:Dental Porcelain / Q000627:therapeutic use*; D019232:Dental Restoration Failure / Q000706:statistics & numerical data*; D019554:Dental Restoration Wear; D003801:Dental Veneers; D003779:Denture Design; D003830:Denture, Partial, Fixed; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014082:Tooth Fractures / Q000628:therapy; D016896:Treatment Outcome; D015040:Zirconium / Q000737:chemistry*
chemical_list: D003776:Dental Porcelain; D015040:Zirconium; C028541:zirconium oxide
keywords: All-ceramic restorations; CAD/CAM; Clinical trials; Fixed dental prostheses; Zirconia