title: A Case of Sepsis in a 92-Year-Old Korean Woman Caused by Aerococcus urinae and Identified by Sequencing the 16S Ribosomal RNA Gene.
abstract: Aerococcus urinae is an uncommon pathogen that was first identified in 1992. Herein, we report a case of bloodstream infection caused by A. urinae, which occurred in a 92-year-old Korean female patient with an underlying urologic infection who had altered consciousness. The blood culture yielded positive results for A. urinae; however, identifying A. urinae was challenging. Ultimately, we used 16S ribosomal RNA (rRNA) gene sequencing to identify the organism. The patient recovered after being treated with ertapenem and meropenem. To our knowledge, this is the first report of a case of A. urinae sepsis in South Korea.
authors: Department of Laboratory Medicine, Graduate School, Kyung Hee University, Seoul, South Korea and Department of Laboratory Medicine, School of Medicine, Kyung Hee University and Kyung Hee University Hospital at Gangdong, Seoul, South Korea.
authors: Min Young
authors: MY
authors: Lee
authors: Department of Laboratory Medicine, School of Medicine, Kyung Hee University and Kyung Hee University Hospital at Gangdong, Seoul, South Korea meikim96@hanmail.net.
authors: Myeong Hee
authors: MH
authors: Kim
authors: Department of Laboratory Medicine, School of Medicine, Kyung Hee University and Kyung Hee University Hospital at Gangdong, Seoul, South Korea.
authors: Woo In
authors: WI
authors: Lee
authors: Department of Laboratory Medicine, School of Medicine, Kyung Hee University and Kyung Hee University Hospital at Gangdong, Seoul, South Korea.
authors: So Young
authors: SY
authors: Kang
authors: Department of Laboratory Medicine, School of Medicine, Kyung Hee University and Kyung Hee University Hospital at Gangdong, Seoul, South Korea.
authors: You La
authors: YL
authors: Jeon
mesh_terms: D056570:Aerococcus / Q000235:genetics*; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000077727:Ertapenem; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D000077731:Meropenem; D012336:RNA, Ribosomal, 16S / Q000032:analysis*; D012074:Remission Induction; D018805:Sepsis / Q000175:diagnosis* / Q000188:drug therapy; D017423:Sequence Analysis, RNA; D013845:Thienamycins / Q000627:therapeutic use; D014552:Urinary Tract Infections / Q000175:diagnosis*; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D012336:RNA, Ribosomal, 16S; D013845:Thienamycins; D047090:beta-Lactams; D000077731:Meropenem; D000077727:Ertapenem
keywords: 16s rRNA sequencing; Aerococcus urinae, sepsis; Kocuria rosea; urinary tract infections