title: A Q-backpropagated time delay neural network for diagnosing severity of gait disturbances in Parkinson's disease.
abstract: Parkinson's disease (PD) is a movement disorder that affects the patient's nervous system and health-care applications mostly uses wearable sensors to collect these data. Since these sensors generate time stamped data, analyzing gait disturbances in PD becomes challenging task. The objective of this paper is to develop an effective clinical decision-making system (CDMS) that aids the physician in diagnosing the severity of gait disturbances in PD affected patients. This paper presents a Q-backpropagated time delay neural network (Q-BTDNN) classifier that builds a temporal classification model, which performs the task of classification and prediction in CDMS. The proposed Q-learning induced backpropagation (Q-BP) training algorithm trains the Q-BTDNN by generating a reinforced error signal. The network's weights are adjusted through backpropagating the generated error signal. For experimentation, the proposed work uses a PD gait database, which contains gait measures collected through wearable sensors from three different PD research studies. The experimental result proves the efficiency of Q-BP in terms of its improved classification accuracy of 91.49%, 92.19% and 90.91% with three datasets accordingly compared to other neural network training algorithms.
authors: Ramanujan Computing Centre, Anna University, Chennai 600025, India.
authors: Y
authors: Y
authors: Nancy Jane
authors: Ramanujan Computing Centre, Anna University, Chennai 600025, India. Electronic address: nehemiah@annauniv.edu.
authors: H
authors: H
authors: Khanna Nehemiah
authors: Department of Information Science and Technology, Anna University, Chennai 600025, India.
authors: Kannan
authors: K
authors: Arputharaj
mesh_terms: D000465:Algorithms; D005260:Female; D020233:Gait Disorders, Neurologic / Q000175:diagnosis*; D006801:Humans; D000069550:Machine Learning; D008297:Male; D008490:Medical Informatics; D016571:Neural Networks, Computer; D010300:Parkinson Disease / Q000503:physiopathology*
keywords: Backpropagation; Clinical decision-making system; Gait; Parkinson’s disease; Q-learning; Time delay neural network