title: Mannose-Binding Lectin Serum Levels in Patients With Candiduria.
abstract: BACKGROUND
  Candida species are normal mycoflora of human body which are capable to cause urinary tract infection (UTI). Mannose-binding lectin (MBL) is a kind of innate immune system and decreasing plasma levels of MBL may disrupt the natural immune response and increase susceptibility to infections.
  
  
  OBJECTIVE
  The aim of the present study was to assess MBL in the serum of patients with candiduria and compare them with control.
  
  
  METHODS
  The blood and urine samples were collected from 335 patients (hospitalized in Golestan hospital, Ahvaz) using standard methods and the growing colonies on CHROMagar were identified using routine diagnostic tests. MBL activity in the serum of 45 patients with candiduria and 45 controls was measured using Eastbiopharm enzyme-linked immunosorbent assay (ELISA) kit.
  
  
  RESULTS
  In this study, 45 (13.4 %) urine samples were positive for Candida species (17 males and 28 females). The most common isolated yeast was Candida albicans (34%), followed by C. glabrata (32.1%), C. tropicalis (9.4%), other Candida species (22.6%), and Rhodotorula species (1.9%). The mean serum levels of MBL were 0.85 ± 0.01 ng/mL and 1.02 ± 0.03 ng/mL among candiduric patients and controls, respectively, and there was no significant difference between the two groups (P = 0.6).
  
  
  CONCLUSIONS
  Our results showed that there was no significant relationship between MBL serum levels and candiduria.
authors: Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Maryam
authors: M
authors: Moslem
authors: Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran; Health Research Institute, Infectious and Tropical Diseases Research Centre, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Ali
authors: A
authors: Zarei Mahmoudabadi
authors: Department of Medical Mycology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Mahnaz
authors: M
authors: Fatahinia
authors: Department of Urology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran.
authors: Alireza
authors: A
authors: Kheradmand
keywords: Candida; Candiduria; Mannose-Binding Lectin