title: Progestin-based contraceptive on the same day as medical abortion.
abstract: OBJECTIVE
  To determine the success rate of medical abortion when a progestin-based contraceptive-either an etonogestrel implant or depot medroxyprogesterone acetate (DMPA) injection-is given on the same day as mifepristone for medical abortion.
  
  
  METHODS
  In a retrospective chart review, data were assessed for women aged 15-49years who underwent medical abortion (≤63days of pregnancy) at two hospitals in KwaZulu Natal, South Africa, between August 2013 and July 2014. The women were given oral mifepristone (200mg) and buccal misoprostol (800μg), and received an etonogestrel implant or DMPA injection on the same day as mifepristone. The primary outcome was the success rate of medical abortion. Comparative data were obtained through a PubMed search.
  
  
  RESULTS
  A total of 89 women were included. Complete termination was achieved in 87 (98%, 95% confidence interval 95%-100%) women. This success rate is similar to that reported in a previous systematic review of the rate of medical abortion success without progestin contraceptive administration (94.8%).
  
  
  CONCLUSIONS
  Administration of a progestin-based contraceptive such as an etonogestrel implant or DMPA injection on the same day as mifepristone for medical abortion did not alter the success rates.
authors: Department of Obstetrics and Gynecology, University of Illinois, Chicago, USA. Electronic address: jeanna.park@gmail.com.
authors: Jeanna
authors: J
authors: Park
authors: Department of Obstetrics and Gynecology, University of Illinois, Chicago, USA.
authors: Nuriya
authors: N
authors: Robinson
authors: Department of Obstetrics and Gynecology, Lower Umfolozi District War Memorial Hospital, Empangeni, South Africa.
authors: Ursula
authors: U
authors: Wessels
authors: Department of Obstetrics and Gynecology, Lower Umfolozi District War Memorial Hospital, Empangeni, South Africa.
authors: James
authors: J
authors: Turner
authors: Department of Obstetrics and Gynecology, University of Illinois, Chicago, USA; Department of Obstetrics and Gynecology, Center for Research on Women and Gender, Chicago, USA.
authors: Stacie
authors: S
authors: Geller
mesh_terms: D000028:Abortion, Induced / Q000706:statistics & numerical data*; D000293:Adolescent; D000328:Adult; D003271:Contraceptive Agents, Female / Q000008:administration & dosage*; D003274:Contraceptive Devices, Female / Q000706:statistics & numerical data*; D017135:Desogestrel / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D017258:Medroxyprogesterone Acetate / Q000008:administration & dosage; D008875:Middle Aged; D015735:Mifepristone / Q000008:administration & dosage; D016595:Misoprostol / Q000008:administration & dosage; D011247:Pregnancy; D011372:Progestins / Q000008:administration & dosage*; D012189:Retrospective Studies; D013019:South Africa; D013997:Time Factors; D055815:Young Adult
chemical_list: D003271:Contraceptive Agents, Female; D011372:Progestins; D016595:Misoprostol; C044815:etonogestrel; D015735:Mifepristone; D017135:Desogestrel; D017258:Medroxyprogesterone Acetate
keywords: Depot medroxyprogesterone acetate; Etonogestrel; Medical abortion