title: Assessment of Predictive Response Factors to Intragastric Balloon Therapy for the Treatment of Obesity.
abstract: BACKGROUND
  Obesity is a worldwide epidemic that is difficult to control with non-invasive treatments, which usually present poor results. In this context, the intragastric balloon (IGB) is an important tool that presents a mean body weight loss (BWL) estimated at approximately 12%, although individual responses are highly variable.
  
  
  OBJECTIVE
  This study assesses whether there are factors that can predict responses to IGB therapy either before or early after placement of the device.
  
  
  METHODS
  A total of 50 obese patients underwent insertion of IGB placed endoscopically, and patients were monitored for 6 months. The evaluated predictive factors involved general characteristics and psychological, social, and dyspeptic aspects, and the preliminary results obtained in the first month after balloon placement.
  
  
  RESULTS
  The mean weight loss was 11.5%, and 48% of the participants presented BWL >10%. Among the factors analyzed before IGB placement, only advanced age (P = .04) and higher scores obtained in the social relationships domain of a shorter version of the World Health Organization's Quality of Life questionnaire (P = .02) were significant. Analysis of the factors evaluated after IGB placement revealed that the BWL amounts observed in week 2 (P = .001) and week 4 (P < .001) and the intensity of dyspeptic symptoms in week 2 (P < .001) were positive predictive factors.
  
  
  CONCLUSIONS
  The assessment of predictive factors may help to manage patients with IGB.
authors: 1 Postgraduate Programme in Endocrinology, Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Eduardo
authors: E
authors: Madeira
authors: 1 Postgraduate Programme in Endocrinology, Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Miguel
authors: M
authors: Madeira
authors: 1 Postgraduate Programme in Endocrinology, Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Erika Paniago
authors: EP
authors: Guedes
authors: 2 Postgraduate Programme in Medical Sciences, State University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Thiago Thomaz
authors: TT
authors: Mafort
authors: 1 Postgraduate Programme in Endocrinology, Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Leonardo Vieira
authors: LV
authors: Neto
authors: 3 Endocrinology Department, The Capriglione Luiz State Institute of Diabetes and Endocrinology , Rio de Janeiro, Brazil .
authors: Rodrigo
authors: R
authors: de Oliveira Moreira
authors: 2 Postgraduate Programme in Medical Sciences, State University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Paulo Roberto Alves
authors: PR
authors: de Pinho
authors: 2 Postgraduate Programme in Medical Sciences, State University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Agnaldo José
authors: AJ
authors: Lopes
authors: 1 Postgraduate Programme in Endocrinology, Federal University of Rio de Janeiro , Rio de Janeiro, Brazil .
authors: Maria Lucia Fleiuss
authors: ML
authors: Farias
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D015905:Gastric Balloon; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D015431:Weight Loss