title: Suture materials - Current and emerging trends.
abstract: Surgical sutures are used to facilitate closure and healing of surgical- or trauma-induced wounds by upholding tissues together to facilitate healing process. There is a wide range of suture materials for medical purpose and the main types include absorbable and nonabsorbable. Recently, there is a growth in the development of classes of suture materials based on their properties and capabilities to improve tissue approximation and wound closure. This review outlines and discusses the current and emerging trends in suture technology including knotless barbed sutures, antimicrobial sutures, bio-active sutures such as drug-eluting and stem cells seeded sutures, and smart sutures including elastic, and electronic sutures. These newer strategies expand the versatility of sutures from being used as just a physical entity approximating opposing tissues to a more biologically active component enabling delivery of drugs and cells to the desired site with immense application potential in both therapeutics and diagnostics. © 2016 Wiley Periodicals, Inc. J Biomed Mater Res Part A: 104A: 1544-1559, 2016.
authors: Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.
authors: Christopher
authors: C
authors: Dennis
authors: GROW Research Laboratory, Narayana Nethralaya Foundation, Bangalore, Karnataka, 560099, India.
authors: Swaminathan
authors: S
authors: Sethu
authors: Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.|School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, 632014, India.
authors: Sunita
authors: S
authors: Nayak
authors: Surface Engineering Division, CSIR - National Aerospace Laboratories, Bangalore, Karnataka, 560017, India.
authors: Loganathan
authors: L
authors: Mohan
authors: Biomechanical and Tissue Engineering Labs, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Australia.
authors: Yosry Yos
authors: YY
authors: Morsi
authors: Centre for Biomaterials Science and Technology, School of Mechanical and Building Sciences, VIT University, Vellore, Tamil Nadu, 632014, India.
authors: Geetha
authors: G
authors: Manivasagam
mesh_terms: D000818:Animals; D000890:Anti-Infective Agents / Q000494:pharmacology; D001672:Biocompatible Materials / Q000494:pharmacology*; D006801:Humans; D004364:Pharmaceutical Preparations; D013234:Stem Cells / Q000166:cytology; D013536:Suture Techniques / Q000639:trends*; D013537:Sutures
chemical_list: D000890:Anti-Infective Agents; D001672:Biocompatible Materials; D004364:Pharmaceutical Preparations
keywords: antimicrobial sutures; barbed sutures; drug-eluting sutures; smart sutures; sutures