title: Medical Management of Pediatric Malignant Bowel Obstruction in a Patient with Burkitt's Lymphoma and Ataxia Telangiectasia Using Continuous Ambulatory Drug Delivery System.
abstract: Malignant bowel obstruction (MBO) is commonly seen in patients with advanced abdominal cancers. The incidence of pediatric MBO in a patient with Burkitt's lymphoma and ataxia telangiectasia is rare, with no published case reports till now. Conservative management of inoperable MBO results in relief of symptoms and improves quality of life. An 11-year-old boy with Burkitt's lymphoma and ataxia telangiectasia was referred to pediatric palliative care with MBO. The objective of this report is to demonstrate conservative management of pediatric MBO using continuous ambulatory drug delivery system. The patient was initiated on continuous ambulatory drug delivery (CADD) system for symptom relief. MBO was reversed with conservative management and the child was discharged on self-collapsible portable elastomeric continuous infusion pump under the supervision of a local family physician. The child remained comfortable at home for 4 weeks until his death. His parents were satisfied with the child's symptom control, quality of life, and were able to care for the child at home. In a resource-limited setting, managing patients at home using elastomeric continuous infusion pumps instead of expensive automated CADD is a practical pharmacoeconomic approach.
authors: Arunangshu
authors: A
authors: Ghoshal
authors: Naveen
authors: N
authors: Salins
authors: Anuja
authors: A
authors: Damani
authors: Jayita
authors: J
authors: Deodhar
authors: M A
authors: MA
authors: Muckaden
mesh_terms: D000553:Ambulatory Care; D001260:Ataxia Telangiectasia / Q000150:complications*; D002051:Burkitt Lymphoma / Q000150:complications*; D002648:Child; D016503:Drug Delivery Systems; D006801:Humans; D007415:Intestinal Obstruction / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D008297:Male; D010166:Palliative Care / Q000379:methods; D011788:Quality of Life
keywords: Ataxia telangiectasia; Burkitt's lymphoma; continuous ambulatory drug delivery system; palliative care; pediatric malignant bowel obstruction