title: Self-Exfoliated Guanidinium-Based Ionic Covalent Organic Nanosheets (iCONs).
abstract: Covalent organic nanosheets (CONs) have emerged as functional two-dimensional materials for versatile applications. Although π-π stacking between layers, hydrolytic instability, possible restacking prevents their exfoliation on to few thin layered CONs from crystalline porous polymers. We anticipated rational designing of a structure by intrinsic ionic linker could be the solution to produce self-exfoliated CONs without external stimuli. In an attempt to address this issue, we have synthesized three self-exfoliated guanidinium halide based ionic covalent organic nanosheets (iCONs) with antimicrobial property. Self-exfoliation phenomenon has been supported by molecular dynamics (MD) simulation as well. Intrinsic ionic guanidinium unit plays the pivotal role for both self-exfoliation and antibacterial property against both Gram-positive and Gram-negative bacteria. Using such iCONs, we have devised a mixed matrix membrane which could be useful for antimicrobial coatings with plausible medical benefits.
authors: Shouvik
authors: S
authors: Mitra
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Sharath
authors: S
authors: Kandambeth
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Bishnu P
authors: BP
authors: Biswal
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Abdul
authors: A
authors: Khayum M
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Chandan K
authors: CK
authors: Choudhury
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Mihir
authors: M
authors: Mehta
authors: Department of Chemistry, Indian Institute of Technology , Kanpur 208016, India.
authors: Gagandeep
authors: G
authors: Kaur
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Subhrashis
authors: S
authors: Banerjee
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Asmita
authors: A
authors: Prabhune
authors: Department of Chemistry, Indian Institute of Technology , Kanpur 208016, India.
authors: Sandeep
authors: S
authors: Verma
authors: Sudip
authors: S
authors: Roy
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Ulhas K
authors: UK
authors: Kharul
authors: Academy of Scientific and Innovative Research (AcSIR) , New Delhi 110020, India.
authors: Rahul
authors: R
authors: Banerjee
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry*; D019791:Guanidine / Q000737:chemistry*; D008958:Models, Molecular; D056004:Molecular Dynamics Simulation; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D000890:Anti-Infective Agents; D019791:Guanidine