title: Four hepatosplenic T-cell lymphoma cases of Japanese patients.
abstract: Hepatosplenic T-cell lymphoma (HSTCL), a rare type of γδ T-cell lymphoma, is characterized by hepatosplenomegaly and cytopenias. It is associated with immunodeficiency and its age of onset is reportedly between the 20s and 30s. We herein report 4 Japanese HSTCL cases. Three of them, including an elderly case that was 74 years of age, were not at adolescence. No cases had a history of immunodeficiency. All other disease phenotypes were similar to the typical HSTCL cases. These findings suggest that there are a certain proportion of HSTCL patients who presented after middle age.
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Hidetsugu
authors: H
authors: Kawai
authors: Department of Laboratory Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Hiromichi
authors: H
authors: Matsushita
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Ken
authors: K
authors: Ohmachi
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Minoru
authors: M
authors: Kojima
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Shinichiro
authors: S
authors: Machida
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Yoshiaki
authors: Y
authors: Ogawa
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Hiroshi
authors: H
authors: Kawada
authors: Department of Pathology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Naoya
authors: N
authors: Nakamura
authors: Department of Hematology/Oncology, Tokai University School of Medicine, Isehara, Kanagawa, Japan.
authors: Kiyoshi
authors: K
authors: Ando
keywords: Elderly patients; Hepatosplenic T-cell lymphoma; Immunodeficiency