title: Margins for cervical and vulvar cancer.
abstract: Surgery is the primary treatment for vulvar cancer as well as early-stage carcinoma of the cervix. This article reviews the significance of margin status after surgery on overall survival, need for further surgical intervention, and role for possible adjuvant therapy. It summarizes the abundant literature on margin status in vulvar cancer and highlights the need for further investigation on the prognostic significance of margins in cervical cancer. In addition, it reviews other important operative considerations.
authors: Division of Gynecologic Oncology, Winship Cancer Institute, Atlanta, Georgia.|Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
authors: Namita
authors: N
authors: Khanna
authors: Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
authors: Lisa A
authors: LA
authors: Rauh
authors: Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
authors: Mark P
authors: MP
authors: Lachiewicz
authors: Division of Gynecologic Oncology, Winship Cancer Institute, Atlanta, Georgia.|Department of Gynecology and Obstetrics, Emory University School of Medicine, Atlanta, Georgia.
authors: Ira R
authors: IR
authors: Horowitz
mesh_terms: D017024:Chemotherapy, Adjuvant; D018572:Disease-Free Survival; D004598:Electrosurgery; D005260:Female; D059247:Fertility Preservation; D005629:Frozen Sections; D006801:Humans; D007044:Hysterectomy / Q000379:methods* / Q000592:standards*; D007432:Intraoperative Period; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D009367:Neoplasm Staging; D018365:Neoplasm, Residual / Q000517:prevention & control; D059351:Organ Sparing Treatments / Q000379:methods / Q000592:standards; D011237:Predictive Value of Tests; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D015996:Survival Rate; D000069339:Trachelectomy / Q000592:standards; D014481:United States / Q000453:epidemiology; D002583:Uterine Cervical Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery*; D014846:Vulvar Neoplasms / Q000453:epidemiology / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery*
keywords: cervical neoplasms; vulvar neoplasms