title: Coexistence of splenic hemangioma and vascular malformation of the vertebrae.
abstract: BACKGROUND
  Cavernous hemangioma is an encapsulated mass of dilated, endothelial lined vascular channels filled with slowly flowing blood. Cavernous hemangioma of the spleen is a rare condition with less than 100 reports so far. Hemangioma of the vertebral is a benign vascular legion around one or two vertebrae. These are usually asymptomatic and discovered incidentally. In this study we reported an extreme rare case of splenic hemangioma coexistence with vascular malformation of the vertebrae. To our knowledge this is the first report of coexistence of splenic hemangioma and hemangioma of the vertebra.
  
  
  METHODS
  A 20-year-old iranian male with splenomegaly, abdominal pain, diarrhea and pancytopenia who was first highly suspicious for malignancy referred to our center for evaluation of the diagnostic workup. After full examination we detected a very rare case with a giant, solitary cavernous hemangioma of the spleen and multiple hemangiomas in his vertebrae. Histopathology of the spleen showed a large cavernous hemangioma occupying almost the entire spleen with large areas of infarction necrosis with multiple hemangiomas of the vertebrae.
  
  
  CONCLUSIONS
  It is extremely rare to have a splenic hemangioma concurrent with vertebra hemangioma and this is clinically very important to consider splenic hemangioma in differential diagnosis of splenomegaly for a better therapeutic management in related patients.
authors: AJA Cancer Research Center (ACRC), AJA University of Medical Sciences, Tehran, Iran. Jalaeikhoo@gmail.com.
authors: Hasan
authors: H
authors: Jalaeikhoo
authors: AJA Trauma and Surgery Research Center, AJA University of Medical Sciences, Tehran, Iran. mehdi.ariana2010@gmail.com.
authors: Mehdi
authors: M
authors: Ariana
authors: Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. kashfihossein@yahoo.com.
authors: Seyed Mohammad Hossein
authors: SM
authors: Kashfi
authors: Gastroenterology and Liver Diseases Research Center, Research Institute for Gastroenterology and Liver Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. azimzadeh.pedram@gmail.com.
authors: Pedram
authors: P
authors: Azimzadeh
authors: AJA Cancer Research Center (ACRC), AJA University of Medical Sciences, Tehran, Iran. DoctorNarimani@gmail.com.
authors: Ahmad
authors: A
authors: Narimani
authors: AJA Cancer Research Center (ACRC), AJA University of Medical Sciences, Tehran, Iran. Mdadpay@yahoo.com.
authors: Masoomeh
authors: M
authors: Dadpay
authors: Hematology and Oncology Research Center, Vali Asr Hospital, Tehran University of Medical Science, Tehran, Iran. mkeyhani@hotmail.com.
authors: Manouchehr
authors: M
authors: Keyhani
mesh_terms: D006391:Hemangioma / Q000150:complications*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013131:Spine / Q000098:blood supply* / Q000473:pathology; D013154:Spleen / Q000473:pathology; D013160:Splenic Neoplasms / Q000150:complications* / Q000473:pathology; D054079:Vascular Malformations / Q000150:complications*; D055815:Young Adult