title: Compromised salivary parameters of children with juvenile idiopathic arthritis.
abstract: OBJECTIVE
  To evaluate the salivary parameters of individuals with juvenile idiopathic arthritis (JIA) and determine if there is a correlation with the simplified oral hygiene index (OHI-S).
  
  
  METHODS
  Stimulated whole saliva was collected from children, aged 6 to 12 years, with JIA (n = 36) and compared with saliva from a control group (CG) composed of healthy children matched by demographic characteristics (n = 36). Salivary parameters evaluated were amylase and peroxidase activities, calcium, phosphate, and total sialic acid concentration. Data were compared by two-tailed Student's t test, and salivary parameters were evaluated for correlations with OHI-S by Spearman's correlation.
  
  
  RESULTS
  The JIA group had a statistically significant reduction in all salivary parameters: α-amylase (20%) (CG, 9.84 ± 4.23; JIA 4.80 ± 3.10) and peroxidase (55%) (CG, 35.05 ± 14.97; JIA, 15.78 ± 6.44) activities, total sialic acid (25%) (CG, 0.024 ± 0.01; JIA, 0.010 ± 0.04), calcium (13%) (CG, 6.26 ± 2.26; JIA, 5.44 ± 2.26) and phosphate (50%) (CG, 10.88 ± 1.49; JIA, 5.45 ± 0.88) concentration compared with the CG (P ≤ .05). There were no significant correlations between the salivary parameters and OHI-S in either group.
  
  
  CONCLUSIONS
  JIA patients showed a reduction of different salivary parameters involved in maintaining oral health.
authors: Department of Pediatric Dentistry at the University Cruzeiro do Sul, São Paulo, SP, Brazil.
authors: Bruna
authors: B
authors: de Oliveira Perestrelo
authors: Centro Universitário de Volta Redonda (UniFoa), Volta Redonda, RJ, Brazil.
authors: Alice Rodrigues
authors: AR
authors: Feres de Melo
authors: Department of Pediatric Dentistry at the University Cruzeiro do Sul, São Paulo, SP, Brazil.
authors: Giselle Rodrigues
authors: GR
authors: de Sant'Anna
authors: Department of Pediatric Dentistry at the University Cruzeiro do Sul, São Paulo, SP, Brazil. Electronic address: marianafl@hotmail.com.
authors: Mariana Ferreira
authors: MF
authors: Leite
mesh_terms: D001171:Arthritis, Juvenile / Q000150:complications*; D001938:Brazil; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009911:Oral Hygiene Index; D012463:Saliva / Q000737:chemistry*