title: OESOPHAGEAL CANDIDIASIS IN AN IMMUNOCOMPETENT ADULT, AN ADVERSE EFFECT OF ANTIBIOTIC THERAPY FOLLOWING CARDIAC SURGERY, CASE REPORT AND REVIEW OF LITERATURE.
abstract: Dysphagia following cardiac surgery is a frequently encountered problem, being most commonly due to the sternotomy incision and/or prolonged intubation. Oesophageal candidiasis is an increasing problem that is usually associated with immunosuppression or immunodeficiency. We report a 59 years age, immunocompetent lady whom had developed dysphagia and odynophagia following open cardiac surgery and long term course of antibiotics. Diagnosis of Candida oesophagitis was established after radiological, endoscopic and microbiological evidence, and successful treatment with combined topical and systemic antifungal therapy was achieved. Possibility of immunodeficiency was excluded. We believe that this lady developed oesophageal candidiasis due to a long-term course of broad spectrum antibiotics. We discuss the various diagnostic modalities and treatment options.
authors: Cardiothoracic Department, ElShaab Teaching Hospital, Khartoum, Sudan.
authors: M E
authors: ME
authors: Ahmed
authors: M S
authors: MS
authors: Elfeil
authors: I A
authors: IA
authors: Ali
authors: M I
authors: MI
authors: Abdelrahim
authors: A A
authors: AA
authors: Tamim
authors: M K
authors: MK
authors: Khalid
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000009:adverse effects*; D000935:Antifungal Agents / Q000627:therapeutic use*; D002180:Candidiasis, Oral / Q000150:complications* / Q000188:drug therapy; D003680:Deglutition Disorders / Q000382:microbiology*; D004106:Dilatation / Q000379:methods; D004359:Drug Therapy, Combination; D004941:Esophagitis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008875:Middle Aged; D009761:Nystatin / Q000627:therapeutic use; D013903:Thoracic Surgery; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D009761:Nystatin; D000666:Amphotericin B