title: Expression of Sox genes in tooth development.
abstract: Members of the Sox gene family play roles in many biological processes including organogenesis. We carried out comparative in situ hybridization analysis of seventeen sox genes (Sox1-14, 17, 18, 21) during murine odontogenesis from the epithelial thickening to the cytodifferentiation stages. Localized expression of five Sox genes (Sox6, 9, 13, 14 and 21) was observed in tooth bud epithelium. Sox13 showed restricted expression in the primary enamel knots. At the early bell stage, three Sox genes (Sox8, 11, 17 and 21) were expressed in pre-ameloblasts, whereas two others (Sox5 and 18) showed expression in odontoblasts. Sox genes thus showed a dynamic spatio-temporal expression during tooth development.
authors: Division of Oral Anatomy, Department of Oral Biological Science, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
authors: Katsushige
authors: K
authors: Kawasaki
authors: Maiko
authors: M
authors: Kawasaki
authors: Momoko
authors: M
authors: Watanabe
authors: Erik
authors: E
authors: Idrus
authors: Takahiro
authors: T
authors: Nagai
authors: Shelly
authors: S
authors: Oommen
authors: Takeyasu
authors: T
authors: Maeda
authors: Nobuko
authors: N
authors: Hagiwara
authors: Jianwen
authors: J
authors: Que
authors: Paul T
authors: PT
authors: Sharpe
authors: Atsushi
authors: A
authors: Ohazama
mesh_terms: D000818:Animals; D004622:Embryo, Mammalian / Q000166:cytology / Q000378:metabolism*; D018507:Gene Expression Regulation, Developmental; D017403:In Situ Hybridization; D051379:Mice; D008822:Mice, Transgenic; D009805:Odontogenesis / Q000502:physiology*; D055755:SOXD Transcription Factors / Q000502:physiology*; D014083:Tooth Germ / Q000166:cytology / Q000378:metabolism*
chemical_list: D055755:SOXD Transcription Factors; C095939:Sox6 protein, mouse