title: Contact lens fitting in a patient with Alport syndrome and posterior polymorphous corneal dystrophy: a case report.
abstract: Alport Syndrome is a hereditary disease that is caused by a gene mutation and affects the production of collagen in basement membranes; this condition causes hemorrhagic nephritis associated with deafness and ocular changes. The X-linked form of this disease is the most common and mainly affects males. Typical ocular findings are dot-and-fleck retinopathy, anterior lenticonus, and posterior polymorphous corneal dystrophy. Some cases involving polymorphous corneal dystrophy and corneal ectasia have been previously described. Here we present a case report of a 33-year-old female with Alport syndrome, posterior polymorphous corneal dystrophy, and irregular astigmatism, whose visual acuity improved with a rigid gas permeable contact lens.
authors: Setor de Lentes de Contato e Refração, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors: Juliana Maria da Silva
authors: JM
authors: Rosa
authors: Setor de Lentes de Contato e Refração, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors: Marcelo Vicente de
authors: MV
authors: Andrade Sobrinho
authors: Setor de Lentes de Contato e Refração, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
authors: César
authors: C
authors: Lipener
mesh_terms: D000328:Adult; D002387:Cataract Extraction; D003261:Contact Lenses; D003317:Corneal Dystrophies, Hereditary / Q000503:physiopathology* / Q000534:rehabilitation*; D019781:Corneal Topography; D005260:Female; D006801:Humans; D009394:Nephritis, Hereditary / Q000503:physiopathology*; D017755:Prosthesis Fitting; D016896:Treatment Outcome; D014792:Visual Acuity