title: Amine-bis(phenolate) Iron(III)-Catalyzed Formal Hydroamination of Olefins.
abstract: A practical synthesis of highly functionalized amines by the formal hydroamination reaction of alkenes with nitroarenes catalyzed by an air stable amine-bis(phenolate) iron(III) complex is reported. The reaction uses an easily handled silane, low catalyst loadings, and mild reaction conditions. A wide range of substrates are transformed with synthetically useful yields (21 examples).
authors: School of Chemistry, Joseph Black Building, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, United Kingdom.
authors: Kailong
authors: K
authors: Zhu
authors: School of Chemistry, Joseph Black Building, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, United Kingdom. michael.shaver@ed.ac.uk.
authors: Michael P
authors: MP
authors: Shaver
authors: School of Chemistry, Joseph Black Building, University of Edinburgh, David Brewster Road, Edinburgh, EH9 3FJ, United Kingdom. stephen.thomas@ed.ac.uk.
authors: Stephen P
authors: SP
authors: Thomas
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000586:Amination; D000588:Amines / Q000138:chemical synthesis* / Q000737:chemistry*; D002384:Catalysis; D005290:Ferric Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010636:Phenols / Q000737:chemistry*
chemical_list: D000475:Alkenes; D000588:Amines; D005290:Ferric Compounds; D010636:Phenols
keywords: amine-bis(phenolate); hydroamination; iron; radicals; silanes