title: Presurgical Mapping of the Language Network Using Resting-state Functional Connectivity.
abstract: Resting-state functional magnetic resonance imaging (resting-state fMRI) is a tool for investigating the functional networks that arise during the resting state of the brain. Recent advances of the resting-state fMRI analysis suggest its feasibility for evaluating language function. The most common clinical application is for presurgical mapping of cortex for a brain tumor or for resective epilespy surgery. In this article, we review the techniques and presurgical applications of resting-state fMRI analysis for language evaluation, and discuss the use in the clinical setting, focusing on planning for neurosurgery.
authors: *Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown †Institute for Medical Engineering and Science, Harvard-MIT Division of Health Sciences, Technology Massachusetts Institute of Technology, Cambridge, MA.
authors: Naoaki
authors: N
authors: Tanaka
authors: Steven M
authors: SM
authors: Stufflebeam
mesh_terms: D002540:Cerebral Cortex / Q000503:physiopathology* / Q000601:surgery; D063132:Connectome / Q000379:methods; D004558:Electric Stimulation / Q000379:methods*; D004827:Epilepsy / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D064795:Intraoperative Neurophysiological Monitoring / Q000379:methods; D007802:Language; D008279:Magnetic Resonance Imaging / Q000379:methods*; D011300:Preoperative Care / Q000379:methods; D012146:Rest