title: Subchronic exposure to static magnetic field differently affects zinc and copper content in murine organs.
abstract: OBJECTIVE
  Static magnetic fields (SMF) have been widely used in research, medicine and industry. Since zinc and copper play an important role in biological systems, we studied the effects of the subchronic continuous SMF exposure on their distribution in murine tissues.
  
  
  METHODS
  For 30 days, mice were exposed to inhomogeneous, vertical, downward or upward oriented SMF of 1 mT averaged intensity with spatial gradient in vertical direction.
  
  
  RESULTS
  SMF decreased the amount of copper and zinc in liver. In brain, zinc levels were increased and copper levels were decreased. In spleen, zinc content was reduced, while copper amount remained unchanged.
  
  
  CONCLUSIONS
  Subchronic exposure to SMF differently affected copper and zinc content in examined organs, and the changes were more pronounced for the downward oriented field. The outcome could be attributed to the protective, rather than the harmful effect of SMF.
authors: a Department of Pathological Physiology, School of Medicine , University of Belgrade , Belgrade , Serbia;
authors: Silvio R
authors: SR
authors: De Luka
authors: b Institute of Physics , University of Belgrade , Zemun-Belgrade , Serbia;
authors: Andjelija Ž
authors: AŽ
authors: Ilić
authors: c Institute of Meat Hygiene and Technology , Belgrade , Serbia.
authors: Saša
authors: S
authors: Janković
authors: a Department of Pathological Physiology, School of Medicine , University of Belgrade , Belgrade , Serbia;
authors: Drago M
authors: DM
authors: Djordjevich
authors: b Institute of Physics , University of Belgrade , Zemun-Belgrade , Serbia;
authors: Saša
authors: S
authors: Ćirković
authors: a Department of Pathological Physiology, School of Medicine , University of Belgrade , Belgrade , Serbia;
authors: Ivan D
authors: ID
authors: Milovanovich
authors: c Institute of Meat Hygiene and Technology , Belgrade , Serbia.
authors: Srdjan
authors: S
authors: Stefanović
authors: c Institute of Meat Hygiene and Technology , Belgrade , Serbia.
authors: Slavica
authors: S
authors: Vesković-Moračanin
authors: b Institute of Physics , University of Belgrade , Zemun-Belgrade , Serbia;
authors: Jasna L
authors: JL
authors: Ristić-Djurović
authors: a Department of Pathological Physiology, School of Medicine , University of Belgrade , Belgrade , Serbia;
authors: Alexander M
authors: AM
authors: Trbovich
mesh_terms: D000818:Animals; D003300:Copper / Q000378:metabolism*; D004307:Dose-Response Relationship, Radiation; D060526:Magnetic Fields; D008297:Male; D051379:Mice; D009928:Organ Specificity / Q000502:physiology / Q000528:radiation effects; D011829:Radiation Dosage; D014018:Tissue Distribution; D014781:Viscera / Q000502:physiology* / Q000528:radiation effects*; D014916:Whole-Body Irradiation / Q000379:methods*; D015032:Zinc / Q000378:metabolism*
chemical_list: D003300:Copper; D015032:Zinc
keywords: Inhomogeneous SMF of different orientation; brain; copper; liver; spleen; zinc