title: Analytical evaluation of the epoc® point-of-care blood analysis system in cardiopulmonary bypass patients.
abstract: OBJECTIVE
  The aim of this study was to evaluate the analytical performance of the new epoc® point-of-care blood analysis system in cardiopulmonary bypass patients.
  
  
  METHODS
  The precision study was conducted on 3 epoc® blood analysis systems using 5 levels of quality control materials twice per day for 5days. The blood specimen was collected in blood gas syringes from 40 cardiac perfusion patients for the comparison study on epoc® (all 3meters), Instrumentation Laboratory GEM4000, Abbott iSTAT, Nova CCX, and Roche Accu-Chek Inform II and Performa glucose meters.
  
  
  RESULTS
  The epoc® blood analysis systems demonstrated clinically acceptable precision for all analytes (from 0.07%, 0.07%, and 0.13% for pH7.6, 7.4, and 7.0 levels; to 3.87%, 3.74%, and 7.56% for pO2 197, 103, and 56mmHg levels). Comparison studies yielded a correlation coefficient R from 0.9201 (sodium) to 0.9969 (pO2) with the GEM4000; from 0.9071 (sodium) to 0.9965 (potassium) with the iSTAT; from 0.8793 (sodium) to 0.9957 (pO2) with the CCX, and 0.9850 and 0.9904 with Roche Inform II and Performa meters respectively. Average biases for all analytes were within the total allowable error limits.
  
  
  CONCLUSIONS
  The epoc® blood analysis system is acceptable for point-of-care testing in the cardiovascular surgery setting.
authors: Department of Laboratory Medicine, Dr. Everett Chalmers Regional Hospital, Horizon Health Network, Fredericton, NB, Canada; Faculty of Medicine, University College Cork, Cork, Ireland.
authors: Jianing
authors: J
authors: Chen
authors: Department of Laboratory Medicine, Saint John Regional Hospital, Horizon Health Network, Saint John, NB, Canada.
authors: Monique
authors: M
authors: Gorman
authors: Division of Cardiac Perfusion, Saint John Regional Hospital, Horizon Health Network, Saint John, NB, Canada.
authors: Bill
authors: B
authors: O'Reilly
authors: Department of Laboratory Medicine, Dr. Everett Chalmers Regional Hospital, Horizon Health Network, Fredericton, NB, Canada; Department of Pathology, Dalhousie University, Halifax, NS, Canada. Electronic address: yu.chen@horizonNB.ca.
authors: Yu
authors: Y
authors: Chen
mesh_terms: D001784:Blood Gas Analysis / Q000379:methods*; D001786:Blood Glucose / Q000032:analysis*; D015190:Blood Glucose Self-Monitoring / Q000379:methods; D002315:Cardiopulmonary Bypass; D006403:Hematologic Tests; D006801:Humans; D019095:Point-of-Care Systems / Q000592:standards*; D000067716:Point-of-Care Testing / Q000592:standards*; D011785:Quality Assurance, Health Care; D011786:Quality Control
chemical_list: D001786:Blood Glucose
keywords: Blood gas analysis; Cardiac surgery; Comparison study; Method evaluation; Point-of-care testing; epoc®