title: Psychosocial impact of mast cell disorders: Pilot investigation of a rare and understudied disease.
abstract: Mast cell disorders are rare, chronic diseases involving unpredictable physical symptoms ranging in severity, duration, and frequency. Almost two-thirds of participants with these disorders ( n = 180) experienced clinically meaningful depressive symptoms. Depressed mood was associated with somatic symptomatology, poorer quality of life, lower resilience, and indirectly with ways of coping. Newly developed measures for this population performed psychometrically well. There was no gender difference in depression but women reported greater use of several ways of coping, greater disease-related distress, poorer quality of life, and more symptoms. Results underscore the need for further research and development of effective psychosocial interventions for this population.
authors: 1 Stony Brook University, USA.
authors: Jennifer
authors: J
authors: Nicoloro-SantaBarbara
authors: 1 Stony Brook University, USA.
authors: Marci
authors: M
authors: Lobel
authors: 2 Harvard Medical School, USA.
authors: David
authors: D
authors: Wolfe
mesh_terms: D000223:Adaptation, Psychological; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003863:Depression / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008415:Mastocytosis / Q000523:psychology*; D008875:Middle Aged; D010865:Pilot Projects; D011788:Quality of Life / Q000523:psychology*; D035583:Rare Diseases; D013315:Stress, Psychological / Q000523:psychology*; D055815:Young Adult
keywords: chronic illness; coping; depression; quality of life; stress; symptoms