title: Impact of laparoscopic cystectomy of endometriotic and non-endometriotic cysts on ovarian volume, antral follicle count (AFC) and ovarian doppler velocimetry.
abstract: OBJECTIVE
  To evaluate the effect on ovarian reserve and blood flow of unilateral laparoscopic stripping of endometriotic versus non-endometriotic cysts.
  
  
  METHODS
  Prospective observational study.
  
  
  METHODS
  Tertiary university gynecology unit.
  
  
  METHODS
  During the study period, 71 subjects underwent the first laparoscopic surgery for removal of a monolateral benign ovarian cyst.
  
  
  METHODS
  Trans-vaginal ultrasound scans of the pelvis about six months after surgery.
  
  
  METHODS
  Ovarian volume, Antral Follicle Count (AFC) and Resistance Index (RI) of ovarian artery of the operated and the contralateral ovary.
  
  
  RESULTS
  Among 71 cysts, 39.4% were endometriotic and 60.6% non-endometriotic benign cysts. All the procedures were performed by the same experienced surgeons with a standardized technique. No major complications were reported during surgery. The mean (±SD) age and BMI of women were 31.0 ± 6.8 years and 24.2 ± 3.3 kg/m(2), respectively. Mean diameter of the removed cysts was smaller for endometriotic than non-endometriotic cysts (4.35 ± 1.77 cm versus 6.33 ± 3.71 cm, p = 0.046). In comparison to non-operated, volume of the operated ovary was significantly lower and with a reduced AFC, with no difference between endometriotic and non-endometriotic cysts (-2.41 ± 2.35 versus -2.00 ± 2.23 cm(3), p = 0.496) (-3.45 ± 3.07 versus -2.43 ± 1.95, p = 0.11). Ovarian artery RI was higher in the operated ovary with no difference between endometriotic and non-endometriotic cysts (0.19 ± 0.14 versus 0.14 ± 0.10, p = 0.455). The difference in ovarian volume (r = 0.178), AFC (r = 0.094) and RI (r = 0.079) between operated and non-operated ovary was not dependent on the diameter of the removed cyst.
  
  
  CONCLUSIONS
  Ovarian surgery is associated with a decline of ovarian reserve, independently on the histological type and the diameter of the removed cyst.
authors: a Department of Obstetrics , Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero Universitaria Policlinico of Modena , Modena , Italy and.
authors: Angelo
authors: A
authors: Cagnacci
authors: a Department of Obstetrics , Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero Universitaria Policlinico of Modena , Modena , Italy and.
authors: Manuela
authors: M
authors: Bellafronte
authors: a Department of Obstetrics , Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero Universitaria Policlinico of Modena , Modena , Italy and.
authors: Anjeza
authors: A
authors: Xholli
authors: a Department of Obstetrics , Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero Universitaria Policlinico of Modena , Modena , Italy and.
authors: Federica
authors: F
authors: Palma
authors: a Department of Obstetrics , Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero Universitaria Policlinico of Modena , Modena , Italy and.
authors: Maria Maddalena
authors: MM
authors: Carbone
authors: b Department of Obstetrics and Gynecology , University Federico II , Naples , Italy.
authors: Costantino
authors: C
authors: Di Carlo
authors: a Department of Obstetrics , Gynecology and Pediatrics, Obstetrics and Gynecology Unit, Azienda Ospedaliero Universitaria Policlinico of Modena , Modena , Italy and.
authors: Giovanni
authors: G
authors: Grandi
mesh_terms: D000328:Adult; D004715:Endometriosis / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D010535:Laparoscopy; D010048:Ovarian Cysts / Q000209:etiology / Q000601:surgery*; D065851:Ovarian Reserve; D010053:Ovary / Q000098:blood supply* / Q000000981:diagnostic imaging; D011446:Prospective Studies; D018608:Ultrasonography, Doppler
keywords: Antral follicle count; benign ovarian cyst; endometrioma; endometriosis; ovarian reserve; ovarian volume; stripping; teratoma