title: A Review of Autologous Islet Transplantation.
abstract: Autologous islet transplantation after total or semitotal pancreatectomy aims to preserve insulin secretory function and prevent the onset of diabetes. The major indication for pancreatectomy is chronic pancreatitis with severe abdominal pain, a benign pancreatic tumor, and trauma. The metabolic outcome of autologous islet transplantation is better than that of allogeneic transplantation and depends on the number of transplanted islets. Achieving islet isolation from a fibrous or damaged pancreas is one of the biggest challenges of autologous islet transplantation; a major complication is portal vein thrombosis after crude islet infusion. However, the incidence of portal vein thrombosis has decreased as islet preparation techniques have improved over time.
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Michihiro
authors: M
authors: Maruyama
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Takashi
authors: T
authors: Kenmochi
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Naotake
authors: N
authors: Akutsu
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Kazunori
authors: K
authors: Otsuki
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Taihei
authors: T
authors: Ito
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Ikuko
authors: I
authors: Matsumoto
authors: Department of Surgery, NHO Chiba-East National Hospital , Chiba City, Chiba , Japan.
authors: Takehide
authors: T
authors: Asano
keywords: Autologous transplantation; Islet; Total pancreatectomy