title: TBX5 and NuRD Divide the Heart.
abstract: In this issue of Developmental Cell, Waldron et al. (2016) identify an interaction between a master regulator of heart development, TBX5, and the NuRD complex and describe how mutations affecting the interaction may contribute to congenital heart disease. Furthermore, these interactions may have contributed to the evolution of cardiac septation.
authors: Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: cboogerd@ucsd.edu.
authors: Cornelis J
authors: CJ
authors: Boogerd
authors: Skaggs School of Pharmacy and Pharmaceutical Sciences, Departments of Pharmacology and Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: syevans@ucsd.edu.
authors: Sylvia M
authors: SM
authors: Evans
mesh_terms: D000818:Animals; D042002:Chromatin Assembly and Disassembly / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental / Q000235:genetics*; D006321:Heart / Q000196:embryology*; D006801:Humans; D009206:Myocardium / Q000378:metabolism*; D020825:T-Box Domain Proteins / Q000235:genetics*
chemical_list: D020825:T-Box Domain Proteins