title: Transplant related ocular surface disorders: Advanced techniques for ocular surface rehabilitation after ocular complications secondary to hematopoietic stem cell transplantation.
abstract: HSCT has been linked to the development of an assortment of ocular surface complications with the potential to lead to permanent visual impairment if left untreated or if not treated early in the course of disease. Strategies for therapy include maintenance of lubrication and tear preservation, prevention of evaporation, decreasing inflammation, and providing epithelial support. The ultimate aim of treatment is to prevent permanent ocular sequelae through prompt ophthalmology consultation and the use of advanced techniques for ocular surface rehabilitation. We describe several rehabilitation options of ocular surface complications occurring secondarily during the post-HSCT course.
authors: Section of Ophthalmology, Department of Surgery, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
authors: Erin D
authors: http://orcid.org/0000-0002-3951-1700
authors: ED
authors: Stahl
authors: School of Medicine, University of Missouri - Kansas City, Kansas City, MO, USA.
authors: Faheem
authors: F
authors: Mahomed
authors: School of Medicine, University of Missouri - Kansas City, Kansas City, MO, USA.
authors: Amneet K
authors: AK
authors: Hans
authors: Section of Hematology/Oncology/BMT, Department of Pediatrics, Children's Mercy Hospitals and Clinics, Kansas City, MO, USA.
authors: Jignesh D
authors: JD
authors: Dalal
mesh_terms: D000287:Administration, Topical; D000293:Adolescent; D000650:Amnion / Q000378:metabolism; D000755:Anemia, Sickle Cell / Q000628:therapy; D000900:Anti-Bacterial Agents / Q000008:administration & dosage; D002648:Child; D005128:Eye Diseases / Q000209:etiology* / Q000517:prevention & control / Q000534:rehabilitation*; D006086:Graft vs Host Disease / Q000209:etiology; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects* / Q000379:methods; D006801:Humans; D007249:Inflammation; D065346:Lubricant Eye Drops; D008297:Male; D009885:Ophthalmology / Q000379:methods; D012590:Sclera / Q000473:pathology; D013256:Steroids / Q000008:administration & dosage; D013997:Time Factors; D014180:Transplantation / Q000379:methods*; D019737:Transplants
chemical_list: D000900:Anti-Bacterial Agents; D065346:Lubricant Eye Drops; D013256:Steroids
keywords: bone marrow transplantation; complications; graft-vs-host disease; ocular