title: Pain-related behavior was not observed in dairy cattle in the days after liver biopsy, regardless of whether NSAIDs were administered.
abstract: For liver biopsy in cattle, it is routine practice to only provide local anesthesia (LA) to the skin and muscle layers, with visceral tissues remaining unanesthetized. Cattle being biopsied may therefore benefit from additional analgesia. This study aimed to determine if non-steroidal anti-inflammatory drugs would decrease post-biopsy pain in cattle. Twenty-four dairy cows were allocated into four treatment groups: biopsy under LA only; biopsy under LA with ketoprofen; biopsy under LA with meloxicam; and a sham-biopsied control group. Behavior was observed for 4h immediately following biopsy, and for 2h each day for the first three days after biopsy. No significant differences in behavior were found between any treatment groups on any day. This suggests that any post-biopsy pain present was not of enough significance to alter the cows' normal behavior patterns. Without identifying post-biopsy pain, it is not possible to determine what effect NSAID analgesia may have had on alleviating it.
authors: Animal Welfare Science and Bioethics Centre, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: lorelle.barrett@research.uwa.edu.au.
authors: Lorelle A
authors: LA
authors: Barrett
authors: Animal Welfare Science and Bioethics Centre, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: N.J.Beausoleil@massey.ac.nz.
authors: Ngaio J
authors: NJ
authors: Beausoleil
authors: Hopkirk Research Institute, Massey University, Palmerston North 4474, New Zealand. Electronic address: J.Benschop@massey.ac.nz.
authors: Jackie
authors: J
authors: Benschop
authors: Animal Welfare Science and Bioethics Centre, Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Private Bag 11 222, Palmerston North 4442, New Zealand. Electronic address: K.J.Stafford@massey.ac.nz.
authors: Kevin J
authors: KJ
authors: Stafford
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage*; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D001706:Biopsy / Q000662:veterinary*; D002417:Cattle; D005260:Female; D007660:Ketoprofen / Q000008:administration & dosage*; D008099:Liver / Q000601:surgery; D000077239:Meloxicam; D059408:Pain Management / Q000662:veterinary*; D011343:Procaine / Q000008:administration & dosage*; D011897:Random Allocation; D013843:Thiazines / Q000008:administration & dosage*; D013844:Thiazoles / Q000008:administration & dosage*
chemical_list: D000779:Anesthetics, Local; D000894:Anti-Inflammatory Agents, Non-Steroidal; D013843:Thiazines; D013844:Thiazoles; D011343:Procaine; D007660:Ketoprofen; D000077239:Meloxicam
keywords: Analgesia; Behavior; Cattle; Liver biopsy; Pain