title: Site-Selective Intermolecular Oxidative C-3 Alkenylation of 7-Azaindoles at Room Temperature.
abstract: A previously unexplored palladium-catalyzed C-3 selective alkenylation of 7-azaindoles, performed in the presence of Pd(OAc)2 as the catalyst, PPh3 as the ligand, Cu(OTf)2 as an oxidative cocatalyst, and molecular oxygen (O2) as the terminal oxidant at room temperature, has been reported. This direct alkenylation strategy offers a new approach in functionalizing pharmaceutically important 7-azaindoles.
authors: Academy of Scientific and Innovative Research (AcSIR), Jammu-Campus, Jammu-180001, India.|Medicinal Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Jammu-180001, India.
authors: Prakash
authors: P
authors: Kannaboina
authors: Academy of Scientific and Innovative Research (AcSIR), Jammu-Campus, Jammu-180001, India.|Medicinal Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Jammu-180001, India.
authors: K Anil
authors: KA
authors: Kumar
authors: Medicinal Chemistry Division, Indian Institute of Integrative Medicine (CSIR), Jammu-180001, India.
authors: Parthasarathi
authors: P
authors: Das