title: Beneficial effects of silver foam dressing on healing of wounds with ulcers and infection control of burn patients.
abstract: OBJECTIVE
  To assess the beneficial effects of silver foam dressing on the healing of wounds with ulcers and infection control of burn patients.
  
  
  METHODS
  Eighty-four second-degree burn patients were selected and divided into a study group and a control group (n=42). After disinfection and cleaning, wound beds of the study group were covered with silver-containing soft-silicone foam dressing, and wound surfaces of the control group were wiped with 1% silver sulfadiazine cream (60 g/100 cm(2)). The two groups were checked weekly to observe wound healing progress and adverse reactions of the skin around wounds. Wound secretions were collected and subjected to bacterial culture. Related indices were recorded and quantified.
  
  
  RESULTS
  Thirty seven cases of the study group (88.1%) and 36 cases of the control group (85.7%) recovered to normal, and 3 (7.1%) and 2 cases (4.8%) in the two groups failed to recover. The recovery rates of the two groups were similar (P>0.05), but unrecovered patients in the study group had significantly higher proportions of repaired wounds (P<0.05). Wounds of the study group were healed significantly more rapidly than those of the control group (22.3±3.1 vs. 25.1±4.4, P<0.05). The study group had significantly higher proportions of repaired wounds from Day 7 to Day 21 (P<0.05), but the difference became less obvious with extended time to Day 28. The bacterial culture-positive (exceeding 10(5) organisms per gram of tissue) rates of both groups significantly reduced after treatment (Day 7 for the study group and Day 14 for the control group), and the rate of the study group was significantly lower at last (P<0.05). The study and control groups were observed 134 and 149 person-times respectively, with the normal wound-surrounding skin rates of 96.3% (129/134) and 88.6% (132/149) (P>0.05 except for on Day 14). Except for on Day 28, the study group had significantly lower pain scores than those of the control group (P<0.05), especially on Day 7 and Day 14 (P<0.01). From Day 7 to Day 28, the study group was significantly less prone to burning sensation than the control group (P<0.05), but both groups felt anxious during dressing change (P>0.05). Dressing of the study group was changed significantly more easily (P<0.05), but the fixing outcomes were similar (P>0.05).
  
  
  CONCLUSIONS
  Silver foam dressing rapidly, easily and safely resisted wound bacteria, promoted wound healing and shortened recovery time, effectively relieving the pain of patients.
authors: Bo Yang, Department of Burn and Plastic Surgery, The Fourth People's Hospital of Jinan City, Jinan 250031, China.
authors: Bo
authors: B
authors: Yang
authors: Xudong Wang, Department of Burn and Plastic Surgery, Zaozhuang Municipal Hospital, Zaozhuang 277102, China.
authors: Xudong
authors: X
authors: Wang
authors: Zhonghua Li, Department of Burn and Plastic Surgery, The Fourth People's Hospital of Jinan City, Jinan 250031, China.
authors: Zhonghua
authors: Z
authors: Li
authors: Qi Qu, Department of Burn and Plastic Surgery, The Fourth People's Hospital of Jinan City, Jinan 250031, China.
authors: Qi
authors: Q
authors: Qu
authors: Yan Qiu, Department of Hematology, Qilu Hospital of Shandong University, Jinan 250031, China.
authors: Yan
authors: Y
authors: Qiu
keywords: Second-degree burn; Silver foam dressing; Ulcer; Wound infection