title: Renal Leiomyosarcoma. A Report of Two Cases.
abstract: BACKGROUND
  Leiomyosarcoma represents a rather uncommon malignancy, and reports of cases characterized by a renal genesis are particularly rare.
  
  
  METHODS
  We describe 2 cases of leiomyosarcoma of the kidney, in a 63-year-old woman and in a 53-year-old man, respectively. Both tumors share a common immunohistochemical profile with a strong positivity for smooth muscle actin, a focal positivity for desmin, and negativity for cytokeratins and other markers.
  
  
  CONCLUSIONS
  We provide a comparison between our findings and the data available in the literature, and we note an interesting relatively long survival in our patients (10 months for the first case and 20 months for the second case).
authors: Gabriele
authors: G
authors: Gaggero
authors: Bruno
authors: B
authors: Spina
authors: Francesca
authors: F
authors: Sarocchi
authors: Gian Luigi
authors: GL
authors: Ravetti
authors: Carlo
authors: C
authors: Toncini
authors: Giulio Fraternali
authors: GF
authors: Orcioni
authors: Carlo
authors: C
authors: Greco
authors: António
authors: A
authors: Lopez-Beltran
mesh_terms: D005260:Female; D006801:Humans; D007150:Immunohistochemistry / Q000379:methods; D007633:Keratins / Q000378:metabolism; D007680:Kidney Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology*; D007890:Leiomyosarcoma / Q000175:diagnosis / Q000401:mortality / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012983:Soft Tissue Neoplasms / Q000473:pathology
chemical_list: D007633:Keratins