title: Gaq signaling is required for the maintenance of MLL-AF9-induced acute myeloid leukemia.
authors: Cancer and Stem Cell Biology Group, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
authors: J R
authors: JR
authors: Lynch
authors: Cancer and Stem Cell Biology Group, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
authors: H
authors: H
authors: Yi
authors: Acute Leukemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.|Department of Haematology, SA Pathology and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors: D A
authors: DA
authors: Casolari
authors: Cancer and Stem Cell Biology Group, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
authors: F
authors: F
authors: Voli
authors: Cancer and Stem Cell Biology Group, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
authors: E
authors: 0000-0003-4323-2904
authors: E
authors: Gonzales-Aloy
authors: Leukaemia and Stem Cell Biology Group, Department of Haematological Medicine, King's College London, Denmark Hill, London, UK.
authors: T K
authors: TK
authors: Fung
authors: Kids Cancer Alliance, Translational Cancer Research Centre for Kids, Cancer Institute New South Wales, Sydney, NSW, Australia.
authors: B
authors: B
authors: Liu
authors: Acute Leukemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.|Department of Genetics and Molecular Pathology, SA Pathology, Adelaide, South Australia, Australia.
authors: A
authors: A
authors: Brown
authors: Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.|Centre for Childhood Cancer Research, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors: T
authors: T
authors: Liu
authors: Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.
authors: M
authors: M
authors: Haber
authors: Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.|Centre for Childhood Cancer Research, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors: M D
authors: MD
authors: Norris
authors: Acute Leukemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.|Department of Haematology, SA Pathology and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors: I D
authors: ID
authors: Lewis
authors: Leukaemia and Stem Cell Biology Group, Department of Haematological Medicine, King's College London, Denmark Hill, London, UK.
authors: C W E
authors: CW
authors: So
authors: Acute Leukemia Laboratory, Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, South Australia, Australia.|Department of Haematology, SA Pathology and Royal Adelaide Hospital, Adelaide, South Australia, Australia.
authors: R J
authors: RJ
authors: D'Andrea
authors: Cancer and Stem Cell Biology Group, Children's Cancer Institute, Lowy Cancer Research Centre, University of New South Wales, Sydney, NSW, Australia.|Centre for Childhood Cancer Research, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors: J Y
authors: JY
authors: Wang
mesh_terms: D000818:Animals; D043802:GTP-Binding Protein alpha Subunits, Gq-G11 / Q000378:metabolism*; D064593:Heterografts; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics / Q000378:metabolism* / Q000473:pathology; D051379:Mice; D051788:Myeloid-Lymphoid Leukemia Protein / Q000235:genetics*; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D015398:Signal Transduction / Q000502:physiology; D014407:Tumor Cells, Cultured
chemical_list: C554061:GNAQ protein, human; C474558:MLL-AF9 fusion protein, human; D015514:Oncogene Proteins, Fusion; D051788:Myeloid-Lymphoid Leukemia Protein; D043802:GTP-Binding Protein alpha Subunits, Gq-G11