title: [Application of Rainbow Trout CYP1 Gene Expression Patterns in Gill and Liver for Haihe River Bio-monitoring].
abstract: CYP1 subfamily genes in gills and liver of rainbow trout as biomarkers were studied to establish methods for quantitative mRNA expression analysis of these genes and to determine their expression pattern. Fish caged in various waters in the Haihe River (Tianjin) were analyzed. The mRNA expression patterns observed in Machangjian River and estuary site of Haihe River were markedly similar but at different levels, reflecting that those sites shared the similar pollution components but with different local pollution load. CYP1C1 and 1C3 were only induced at Gegu site and estuary site of Haihe River, indicating different types of CYP1 agonists in Machangjian River. Response patterns of multiple CYP1 genes in gills and liver could be applied in the monitoring strategy. The response patterns of CYP1 genes could be used for better understanding the relationship between complex mixtures of pollutants and biological response of organisms in aquatic environments.
authors: Kai
authors: K
authors: Gao
authors: Pei
authors: P
authors: Yan
authors: Cui-ling
authors: CL
authors: Tan
authors: Yan-he
authors: YH
authors: Luo
authors: Jing
authors: J
authors: Sun
authors: Maria E
authors: ME
authors: Jönsson
authors: Ingvar
authors: I
authors: Brandt
authors: Yun-ping
authors: YP
authors: Tang
mesh_terms: D000818:Animals; D001189:Aryl Hydrocarbon Hydroxylases / Q000235:genetics / Q000378:metabolism*; D002681:China; D004784:Environmental Monitoring; D063366:Estuaries; D029941:Fish Proteins / Q000235:genetics / Q000378:metabolism*; D005880:Gills / Q000201:enzymology; D008099:Liver / Q000201:enzymology; D017686:Oncorhynchus mykiss / Q000235:genetics* / Q000378:metabolism; D045483:Rivers; D014876:Water Pollution
chemical_list: D029941:Fish Proteins; D001189:Aryl Hydrocarbon Hydroxylases