title: Potential Applications of Using 68Ga-Evans Blue PET/CT in the Evaluation of Lymphatic Disorder: Preliminary Observations.
abstract: OBJECTIVE
  Potentials of 68Ga-NEB as a PET tracer in the evaluation of a variety of lymphatic drainage disorders were analyzed.
  
  
  METHODS
  68Ga-NEB was injected subcutaneously, and the PET/CT images were acquired in 13 patients with different suspected lymphatic drainage abnormality. The 68Ga-NEB PET/CT findings were compared with Tc-SC lymphoscintigraphy.
  
  
  RESULTS
  68Ga-NEB activity could be clearly observed in the lymphatic route on the PET/CT images from all the patients. In 5 (38.5%) of 13 patients tested, 68Ga-NEB PET/CT provided more information than the Tc-SC lymphoscintigraphy.
  
  
  CONCLUSIONS
  68Ga-NEB PET/CT can be used as an alternative of Tc-SC lymphoscintigraphy in the evaluation of lymphatic disorders, which enables fast results and might be more accurate than the conventional Tc-SC lymphoscintigraphy.
authors: From the *Department of Nuclear Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College; †Department of Nuclear Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing, People's Republic of China; and ‡Laboratory of Molecular Imaging and Nanomedicine, National Institute of Biomedical Imaging and Bioengineering, National Institutes of Health, Bethesda, MD.
authors: Wei
authors: W
authors: Zhang
authors: Peilin
authors: P
authors: Wu
authors: Fang
authors: F
authors: Li
authors: Guansheng
authors: G
authors: Tong
authors: Xiaoyuan
authors: X
authors: Chen
authors: Zhaohui
authors: Z
authors: Zhu
mesh_terms: D000293:Adolescent; D000328:Adult; D056831:Coordination Complexes; D005260:Female; D006801:Humans; D042601:Lymphatic Vessels / Q000000981:diagnostic imaging; D008209:Lymphedema / Q000000981:diagnostic imaging*; D061305:Lymphoscintigraphy; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D013667:Technetium; D014057:Tomography, X-Ray Computed
chemical_list: C000603981:68Ga-1,4,7-triazacyclononane-N,N',N''-triacetic acid; D056831:Coordination Complexes; D019275:Radiopharmaceuticals; D013667:Technetium