title: Management of chronic pruritus with a UV filtering topical cream.
abstract: Chronic pruritus is a common dermatological condition affecting 10-13% of the general population. UVB phototherapy has been demonstrated to be effective in relieving the symptoms of pruritus. However, phototherapy is rarely administered because the treatment is time-consuming and expensive, when compared to other topical drugs. In previous works, it has been reported that a topical cream, which selectively filters solar UVB can be used as a convenient alternative to traditional phototherapy. Here, we report the results of a pilot study aimed at assessing the effectiveness of the cream for treating pruritus. Seven patients with pruritus symptoms were included in the study. After 3 months of treatment (3 sessions per week), all patients noted improvement in pruritus symptoms. These preliminary results demonstrate that the novel topical cream could provide a convenient, low cost treatment for chronic pruritus patients.
authors: Department of Dermatology and Venereology, University of Rome "G.Marconi", Rome, Italy.
authors: Matteo
authors: M
authors: Zanardelli
authors: Department of Dermatology and Venereology, University of Rome "G.Marconi", Rome, Italy.
authors: Maja
authors: M
authors: Kovacevic
authors: Applied Biology, Irvine, California, USA.
authors: John
authors: J
authors: McCoy
authors: Applied Biology, Irvine, California, USA.
authors: Xingang
authors: X
authors: Wang
authors: Department of Dermatology and Venereology, University of Rome "G.Marconi", Rome, Italy.|Applied Biology, Irvine, California, USA.
authors: Andy
authors: A
authors: Goren
authors: Department of Dermatology and Venereology, University of Rome "G.Marconi", Rome, Italy.
authors: Torello
authors: T
authors: Lotti
mesh_terms: D000279:Administration, Cutaneous; D000328:Adult; D002908:Chronic Disease; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D010865:Pilot Projects; D011537:Pruritus / Q000473:pathology / Q000628:therapy*; D063465:Skin Cream; D016896:Treatment Outcome; D014467:Ultraviolet Therapy / Q000379:methods*
keywords: atopic dermatitis; eczema; phototherapy; pruritus