title: Trends in Age of First-Ever Stroke Following Increased Incidence and Life Expectancy in a Low-Income Chinese Population.
abstract: OBJECTIVE
  We investigated secular trends in the age of stroke onset and stroke incidence in a low-income population in rural China.
  
  
  METHODS
  The study population was recruited from a population-based stroke surveillance study conducted in a township in Tianjin, China, from 1992 to 2014. The trends in mean age and incidence of first-ever stroke were assessed by sex and stroke subtype. Risk factor surveys were conducted in the same population in both 1991 and 2011.
  
  
  RESULTS
  A total of 1053 patients experienced first-ever stroke from 1992 to 2014. The mean age of stroke onset in men significantly decreased by 0.28 years annually overall, by 0.56 years for intracerebral hemorrhage, and by 0.22 years for ischemic stroke (P<0.05). However, a similar trend was not observed in women. The age-standardized first-ever stroke incidence in the same population significantly increased across sex and stroke subtypes, increased by 6.3% overall, 5.5% for men, 7.9% for women, 4.6% for intracerebral hemorrhage, and 7.3% for ischemic stroke (P<0.05) during 1992 to 2014. Concurrently, the prevalence of hypertension, diabetes mellitus, obesity, current smoking, and alcohol consumption increased significantly in young and middle-aged adults from 1991 to 2011.
  
  
  CONCLUSIONS
  The age of stroke onset tends to be younger among low-income population in China after the dramatic increased incidence of stroke during the gradual extension of life expectancy of population in China. These findings suggested that stroke burden will continue to increase in the long time, unless the risk factors in low-income populations are effectively controlled.
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Jinghua
authors: J
authors: Wang
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Lingling
authors: L
authors: Bai
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Min
authors: M
authors: Shi
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Li
authors: L
authors: Yang
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Zhongping
authors: Z
authors: An
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Bin
authors: B
authors: Li
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Wenjuan
authors: W
authors: Zhao
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Hongfei
authors: H
authors: Gu
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Changqing
authors: C
authors: Zhan
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.).
authors: Jun
authors: J
authors: Tu
authors: From the Department of Epidemiology, Tianjin Neurological Institute, Tianjin, China (J.W., L.B., M.S., J.T., X.N.); Department of Neurology, Tianjin Medical University General Hospital, Tianjin, China (J.W., L.B., M.S., L.Y., J.T., X.N.); Department of Neurology, Tianjin Huanhu Hospital, Tianjin, China (Z.A., W.Z.); Department of Neurology, Tianjin Haibin People's Hospital, Tianjin, China (B.L., H.G.); and Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, China (C.Z.). xjn0906@gmail.com.
authors: Xianjia
authors: X
authors: Ning
mesh_terms: D000367:Age Factors; D017668:Age of Onset; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000453:epidemiology*; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D008017:Life Expectancy; D008297:Male; D008875:Middle Aged; D011203:Poverty; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D020521:Stroke / Q000453:epidemiology*
keywords: age; epidemiology; incidence; stroke; trend