title: [TREATMENT OF EXTREMELY PREMATURE NEWBORN INFANT WITH INO. CLINICAL CASE].
abstract: Prolonged inhaled nitric oxide (iNO) from birth in preterm neonates with BPD improves endogenous surfactant function as well as lung growth, angiogenesis, and alveologenesis. As a result there is a reduction in the frequency of the "new" form of BPD in neonates under 28 weeks of gestation and birth weight under 1000 gr. Delivery of inhaled nitric oxide is a new method of prevention of chronic lung disease. According to a large number of randomized trials iNO in premature neonates reduces pulmonary morbidity and leads to a reduction of the mortality in this population of patients. This new therapy does not have serious side effects. We represent a clinical case of extremely premature newborn infant with BPD treated with iNO.
authors: P
authors: P
authors: Radulova
authors: B
authors: B
authors: Slancheva
authors: R
authors: R
authors: Marinov
mesh_terms: D000280:Administration, Inhalation; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D001997:Bronchopulmonary Dysplasia / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D062071:Infant, Extremely Premature / Q000502:physiology; D007231:Infant, Newborn; D007235:Infant, Premature, Diseases / Q000628:therapy*; D008168:Lung / Q000187:drug effects / Q000473:pathology; D008297:Male; D009569:Nitric Oxide / Q000627:therapeutic use*
chemical_list: D001993:Bronchodilator Agents; D009569:Nitric Oxide