title: [The application progress of three-dimensional cell culture technology in ophthalmology].
abstract: Three-dimensional cell culture technology is a kind of technology that cultures the cells in a three-dimensional cultivation by using a kind of scaffold materials in vitro. Its advantage is that the vivo microenvironment simulating degrees of the three-dimensional culture technology is higher than that of the two-dimensional planar cell culture model, and the controllability is also higher than the animal experiment. In recent years, with the development of tissue engineering technology, a varietiy of the stent of biological materials also a fast development, which provided a favorable platform for three-dimensional cell culture technology. In ophthalmology, three-dimensional cell culture has been applied to the cornea, retina and the visual system development and other optic tumor researches. The objective of this paper is to making a review the application status of the three-dimensional cell culture technology in the basic research and clinical treatment in ophthalmology.
authors: Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Hospital and Institute, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China.
authors: Yun
authors: Y
authors: Zhao
authors: Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Hospital and Institute, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China.
authors: Lei
authors: L
authors: Zhang
authors: Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Eye Hospital and Institute, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China; Email: zhaohongeye@126.com.
authors: Hong
authors: H
authors: Zhao
mesh_terms: D000818:Animals; D018929:Cell Culture Techniques / Q000379:methods*; D003315:Cornea; D006801:Humans; D009885:Ophthalmology; D012160:Retina; D023822:Tissue Engineering; D054457:Tissue Scaffolds; D014785:Vision, Ocular