title: Characteristics of Patients With Transitional Cell Carcinoma of the Urinary Bladder in Kermanshah Province, Iran.
abstract: BACKGROUND
  In Iran, bladder cancer is one of the most common malignancy sites among men, ranking as the fifth with age-specific incidence rate of about 11.2 per 100,000 males. It causes 8% of all malignancies in men and 3% of all malignancies in women.
  
  
  OBJECTIVE
  The aim of this study was to report the epidemiological, clinical, and pathological features of bladder cancer in Western Iran compared to other studies.
  
  
  METHODS
  This is a retrospective study between 2003 and 2014 when forty-four patients with bladder cancer referred to Hematology Clinic of Kermanshah, Kermanshah, Iran. Transitional cell carcinoma (TCC) was in 39 patients.
  
  
  RESULTS
  In the patients with TCC, the mean age in diagnosis for them was 65.43 years (± 11.64), range of age 42 to 88 years , thirty-three patients (84.6%) were male, and six patients (15.4%) were female. Of 39 patients with TCC, 16 patients (41%) had metastasis. 21 patients (53.8%) were smoker and 16 patients (41%) had muscle invasive. 35 patients (89.7%) were histological high grade and the rest of patients were low grade. In the TCC patients with increasing age, metastasis and muscle invasive increased.
  
  
  CONCLUSIONS
  The age presentation of TCC in West Iran was similar to other studies. Percentage of patients with high grade is more than other studies, and also the number of patients with bladder cancer has increased during last 4 years. For better results, studies must be conducted with more patients in this area, and other areas of Iran with checking of genetics, race and environmental factors.
authors: Department of Hematology and Medical Oncology, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.
authors: Mehrdad
authors: M
authors: Payandeh
authors: Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, IR Iran; Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.
authors: Masoud
authors: M
authors: Sadeghi
authors: Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, IR Iran; Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, IR Iran.
authors: Edris
authors: E
authors: Sadeghi
keywords: Bladder Cancer; Histological Grade; Transitional Cell Carcinoma