title: Haemosporidian Parasites of Antelopes and Other Vertebrates from Gabon, Central Africa.
abstract: Re-examination, using molecular tools, of the diversity of haemosporidian parasites (among which the agents of human malaria are the best known) has generally led to rearrangements of traditional classifications. In this study, we explored the diversity of haemosporidian parasites infecting vertebrate species (particularly mammals, birds and reptiles) living in the forests of Gabon (Central Africa), by analyzing a collection of 492 bushmeat samples. We found that samples from five mammalian species (four duiker and one pangolin species), one bird and one turtle species were infected by haemosporidian parasites. In duikers (from which most of the infected specimens were obtained), we demonstrated the existence of at least two distinct parasite lineages related to Polychromophilus species (i.e., bat haemosporidian parasites) and to sauropsid Plasmodium (from birds and lizards). Molecular screening of sylvatic mosquitoes captured during a longitudinal survey revealed the presence of these haemosporidian parasite lineages also in several Anopheles species, suggesting a potential role in their transmission. Our results show that, differently from what was previously thought, several independent clades of haemosporidian parasites (family Plasmodiidae) infect mammals and are transmitted by anopheline mosquitoes.
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.|Laboratory of Evolutionary Biology, Ecology and Management of Ecosystems, Faculty of Sciences and Techniques, Cheikh Anta Diop University of Dakar, Dakar, Senegal.
authors: Larson
authors: L
authors: Boundenga
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.|Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.|Institut de Recherche en Ecologie Tropicale, Libreville, Gabon.
authors: Boris
authors: B
authors: Makanga
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.
authors: Benjamin
authors: B
authors: Ollomo
authors: Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Aude
authors: A
authors: Gilabert
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.|Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Virginie
authors: V
authors: Rougeron
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.
authors: Bertrand
authors: B
authors: Mve-Ondo
authors: Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Céline
authors: C
authors: Arnathau
authors: Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Patrick
authors: P
authors: Durand
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.
authors: Nancy Diamella
authors: ND
authors: Moukodoum
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.
authors: Alain-Prince
authors: AP
authors: Okouga
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.
authors: Lucresse
authors: L
authors: Delicat-Loembet
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.
authors: Lauriane
authors: L
authors: Yacka-Mouele
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.|Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Nil
authors: N
authors: Rahola
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.|Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Eric
authors: E
authors: Leroy
authors: Laboratory of Evolutionary Biology, Ecology and Management of Ecosystems, Faculty of Sciences and Techniques, Cheikh Anta Diop University of Dakar, Dakar, Senegal.
authors: Cheikh Tidiane
authors: CT
authors: Ba
authors: Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Francois
authors: F
authors: Renaud
authors: Centre International de Recherches Médicales de Franceville (CIRMF), Franceville, Gabon BP 769 Franceville, Gabon.|Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Franck
authors: F
authors: Prugnolle
authors: Laboratoire MIVEGEC, UMR 224-5290 IRD-CNRS-UM, Centre IRD de Montpellier, 34295 Montpellier, France.
authors: Christophe
authors: C
authors: Paupy
mesh_terms: D000818:Animals; D000852:Anopheles / Q000235:genetics / Q000469:parasitology; D000866:Antelopes / Q000469:parasitology*; D045303:Cytochromes b / Q000235:genetics; D005260:Female; D005681:Gabon / Q000453:epidemiology; D014644:Genetic Variation; D016787:Haemosporida / Q000235:genetics; D007303:Insect Vectors / Q000235:genetics / Q000469:parasitology; D058889:Molecular Typing; D011529:Protozoan Infections, Animal / Q000453:epidemiology / Q000469:parasitology*; D015800:Protozoan Proteins / Q000235:genetics
chemical_list: D015800:Protozoan Proteins; D045303:Cytochromes b