title: [Treatment of corneal endothelial disorders by DMEK and UT-DSAEK. Indications, complications, results and follow-up].
abstract: Various techniques for posterior lamellar keratoplasty have been established for the clinical routine and continuously improved during the last 15 years so that an extremely rapid recovery of vision is possible due to very thin transplants. Descemet membrane endothelial keratoplasty (DMEK) is the method of choice for simple corneal endothelial diseases and has already been applied in complex conditions of the anterior segment. The learning curve for DMEK is comparatively long and the risk of complications in complex anterior segment pathologies is higher than in Descemet's stripping automated endothelial keratoplasty (DSAEK); however, DMEK results in better visual outcome and less graft rejections than DSAEK. The latest evolution in posterior lamellar transplant surgery is ultrathin DSAEK (UT-DSAEK), where the grafted lamella is much thinner than in conventional DSAEK. Currently available data suggest that the resulting visual acuity after UT-DSAEK is close to the visual acuity seen after DMEK; however, studies comparing the results after DMEK and UT-DSAEK are so far lacking. Whether the transplantation of these very thin DSAEK grafts also results in endothelial cell densities and graft rejection rates comparable to DMEK has to be proven.
authors: Zentrum für Augenheilkunde, Universität zu Köln, Kerpenerstr. 62, 50937, Köln, Deutschland. bjoern.bachmann@uk-koeln.de.
authors: B
authors: B
authors: Bachmann
authors: Zentrum für Augenheilkunde, Universität zu Köln, Kerpenerstr. 62, 50937, Köln, Deutschland.
authors: F
authors: F
authors: Schaub
authors: Zentrum für Augenheilkunde, Universität zu Köln, Kerpenerstr. 62, 50937, Köln, Deutschland.
authors: C
authors: C
authors: Cursiefen
mesh_terms: D003316:Corneal Diseases / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D019317:Evidence-Based Medicine; D005500:Follow-Up Studies; D006801:Humans; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D020858:Tissue and Organ Harvesting / Q000379:methods*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D014792:Visual Acuity
keywords: Fuchs’ endothelial dystrophy; Ophthalmic surgeon; Posterior lamellar keratoplasty; Transplant; Visual acuity