title: Mean platelet volume in patients with retinal artery occlusion.
abstract: OBJECTIVE
  The aim of this study was to investigate the mean platelet volume (MPV) of patients with retinal artery occlusion (RAO).
  
  
  METHODS
  Thirty-seven patients diagnosed with RAO and 32 control subjects were included in this retrospective study. Retinal artery occlusion was diagnosed on the basis of clinical examination and fundus fluorescein angiography. All participants underwent complete ocular examination, and MPV, hematocrit, hemoglobin, and platelet counts were recorded. RAO patient data were compared with those of the control subjects.
  
  
  RESULTS
  Patients with RAO had significantly higher MPV values (7.96 ± 1.2 fL) compared with control subjects (7.33 ± 0.7 fL, p<0.001). No significant difference was found with regard to platelet count between the RAO group and the control group (262 ± 70.1 × 109/L and 251 ± 56.6 × 109/L, respectively, p=0.50). MPV was an independent predictor of RAO [odds ratio (OR)=0.50; 95% confidence interval (CI)=0.28-0.89; p=0.019).
  
  
  CONCLUSIONS
  Our results demonstrated that MPV values were significantly higher in patients with RAO, suggesting that larger platelets may contribute to the pathogenesis of the RAOs.
authors: Departments of Ophthalmology, School of Medicine, Dicle University, Diyarbakir, Turkey.
authors: Muhammed
authors: M
authors: Şahin
authors: Departments of Ophthalmology, School of Medicine, Dicle University, Diyarbakir, Turkey.
authors: Alparslan
authors: A
authors: Şahin
authors: Departments of Ophthalmology, School of Medicine, Dicle University, Diyarbakir, Turkey.
authors: Harun
authors: H
authors: Yüksel
authors: Departments of Ophthalmology, School of Medicine, Dicle University, Diyarbakir, Turkey.
authors: Fatih Mehmet
authors: FM
authors: Türkcü
authors: Departments of Ophthalmology, School of Medicine, Dicle University, Diyarbakir, Turkey.
authors: Adnan
authors: A
authors: Yıldırım
mesh_terms: D000328:Adult; D000368:Aged; D001772:Blood Cell Count; D016022:Case-Control Studies; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D012016:Reference Values; D015356:Retinal Artery Occlusion / Q000097:blood*; D012189:Retrospective Studies; D012307:Risk Factors; D018709:Statistics, Nonparametric