title: [Effective pain relief of post-herpetic neuralgia with capsaicin patch].
abstract: Topical 8% capsaicin is a recently approved treatment for post-herpetic neuralgia (PHN). Capsaicin works by causing extensive depolarization of nociceptive epidermal transient receptor potential cation channel V1-positive C-fibers leading to defunctionalization. In this case story a 51-year-old male patient, who was suffering from severe PHN pain and associated allodynia, experienced drastic pain relief upon treatment with topical 8% capsaicin. Pain associated with the patch application could be successfully alleviated by pretreatment with topical lidocaine/prilocaine 2.5% and/or oral tramadol. Topical 8% capsaicin should be considered as a feasible treatment option for PHN.
authors: Hjalte Holm
authors: HH
authors: Andersen
authors: Carsten
authors: C
authors: Sand
authors: jelberling@dadlnet.dk.
authors: Jesper
authors: J
authors: Elberling
mesh_terms: D002211:Capsaicin / Q000008:administration & dosage* / Q000494:pharmacology; D006801:Humans; D008297:Male; D008875:Middle Aged; D051474:Neuralgia, Postherpetic / Q000188:drug therapy*; D010147:Pain Measurement; D018689:Sensory System Agents / Q000008:administration & dosage* / Q000494:pharmacology; D057968:Transdermal Patch
chemical_list: D018689:Sensory System Agents; D002211:Capsaicin