title: Keratinizing desquamative squamous metaplasia in the kidney of a patient with complex spinal cord injury.
abstract: BACKGROUND
  Keratinizing desquamative squamous metaplasia (KDSM) of the upper urinary tract was previously thought, but never proven, to represent a premalignant condition. However, no clear guidelines exist regarding the long-term management and follow up once this rare diagnosis has been made.
  
  
  RESULTS
  Patients with spinal cord injury often develop a range of risk factors for malignancy of the urinary tract. We present the first reported case of KDSM in the kidney of a 44-year-old man with spinal cord injury whose complex urological history includes previous augmentation cystoplasty, recurrent calculi, infections and indwelling catheters.
  
  
  CONCLUSIONS
  Recent literature has suggested a move away from the previous mainstay of treatment with radical surgery towards nephron-sparing endoscopic and radiological surveillance. This case highlights the complexity of preserving renal function in a spinal cord injured patient with KDSM of the kidney.
authors: a Salisbury District Hospital, NHS Foundation Trust , Salisbury , UK.
authors: Jack
authors: J
authors: Coode-Bate
authors: a Salisbury District Hospital, NHS Foundation Trust , Salisbury , UK.
authors: Melissa Clare
authors: MC
authors: Davies
authors: a Salisbury District Hospital, NHS Foundation Trust , Salisbury , UK.
authors: Ian
authors: I
authors: Cook
mesh_terms: D000015:Abnormalities, Multiple / Q000175:diagnosis*; D000328:Adult; D006130:Growth Disorders / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007668:Kidney / Q000473:pathology*; D008297:Male; D008679:Metaplasia; D012868:Skin Abnormalities / Q000150:complications / Q000175:diagnosis*; D013119:Spinal Cord Injuries / Q000150:complications* / Q000175:diagnosis; D014551:Urinary Tract / Q000002:abnormalities*
keywords: Keratinizing desquamative squamous metaplasia; Kidney; Spinal cord injury