title: Risk factors for retinal detachment following cataract surgery: the impact of posterior capsular rupture.
abstract: To investigate risk factors for retinal detachment (RD) after cataract surgery, particularly posterior capsular rupture (PCR) with or without vitreous loss.
  
  
  
  Single centre electronic medical record database study of 18 065 consecutive first eye cataract operations performed between 2005 and 2014. Survival analysis was performed with Kaplan-Meier curves and a Cox proportional hazard regression analysis to calculate HRs with respect to RD.
  
  
  
  The RD rate at 3 months and 7 years was 0.067% and 0.30%, respectively, with a median time to RD of 15 months (mean: 18 months, range: 0-84 months). Men had a higher RD risk (HR 2.00; 95% CI 1.03 to 3.88; p=0.03) in the univariate model. Patients <60 years and those >80 years had an HR of 5.12 (95% CI 2.60 to 10.07; p<0.001) and 0.16 (95% CI 0.38 to 0.69; p=0.01), respectively, compared with patients 60-80 years of age. Eyes longer than 25 mm had an HR of 3.98 (95% CI 1.93 to 8.20; p<0.001) compared with eyes 23-25 mm. PCR occurred in 400 (2.2%) eyes. The HR for RD was 12.83 (95% CI 5.62 to 29.30; p<0.001) for PCR with vitreous loss. There were no RD events in eyes with PCR without vitreous loss.
  
  
  
  The risk for RD after cataract surgery is higher in younger patients and eyes with longer axial length or PCR with vitreous loss during surgery.
authors: Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
authors: Vasileios
authors: V
authors: Petousis
authors: Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
authors: Ahmed A
authors: AA
authors: Sallam
authors: Vitreoretinal Unit, Bristol Eye Hospital, Bristol, UK.
authors: Richard J
authors: RJ
authors: Haynes
authors: Department of Ophthalmology, Oxford Radcliffe Hospitals NHS Foundation Trust, Oxford, UK.
authors: C K
authors: CK
authors: Patel
authors: Department of Ophthalmology, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK.
authors: Ajai K
authors: AK
authors: Tyagi
authors: Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
authors: James N
authors: JN
authors: Kirkpatrick
authors: Department of Ophthalmology, Gloucestershire Hospitals NHS Foundation Trust, Cheltenham, UK.
authors: Robert L
authors: RL
authors: Johnston
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction / Q000009:adverse effects*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007903:Lens Capsule, Crystalline; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012163:Retinal Detachment / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012422:Rupture, Spontaneous; D016019:Survival Analysis; D013997:Time Factors; D006113:United Kingdom / Q000453:epidemiology
keywords: Lens and zonules; Retina; Treatment Surgery; Vitreous