title: DianaHealth.com, an On-Line Database Containing Appraisals of the Clinical Value and Appropriateness of Healthcare Interventions: Database Development and Retrospective Analysis.
abstract: OBJECTIVE
  To describe the development of a novel on-line database aimed to serve as a source of information concerning healthcare interventions appraised for their clinical value and appropriateness by several initiatives worldwide, and to present a retrospective analysis of the appraisals already included in the database.
  
  
  RESULTS
  Database development and a retrospective analysis. The database DianaHealth.com is already on-line and it is regularly updated, independent, open access and available in English and Spanish. Initiatives are identified in medical news, in article references, and by contacting experts in the field. We include appraisals in the form of clinical recommendations, expert analyses, conclusions from systematic reviews, and original research that label any health care intervention as low-value or inappropriate. We obtain the information necessary to classify the appraisals according to type of intervention, specialties involved, publication year, authoring initiative, and key words. The database is accessible through a search engine which retrieves a list of appraisals and a link to the website where they were published. DianaHealth.com also provides a brief description of the initiatives and a section where users can report new appraisals or suggest new initiatives. From January 2014 to July 2015, the on-line database included 2940 appraisals from 22 initiatives: eleven campaigns gathering clinical recommendations from scientific societies, five sets of conclusions from literature review, three sets of recommendations from guidelines, two collections of articles on low clinical value in medical journals, and an initiative of our own.
  
  
  CONCLUSIONS
  We have developed an open access on-line database of appraisals about healthcare interventions considered of low clinical value or inappropriate. DianaHealth.com could help physicians and other stakeholders make better decisions concerning patient care and healthcare systems sustainability. Future efforts should be focused on assessing the impact of these appraisals in the clinical practice.
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Xavier
authors: X
authors: Bonfill
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|Facultad de Ciencias de la Salud Eugenio Espejo, Universidad Tecnológica Equinoccial, Quito, Ecuador.|Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.
authors: Dimelza
authors: D
authors: Osorio
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Ivan
authors: I
authors: Solà
authors: CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Unidad de Epidemiología Clínica y Soporte Metodológico, UICEC de BioCruces-SCReN, Barakaldo, Spain.
authors: Jose Ignacio
authors: JI
authors: Pijoan
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.
authors: Valentina
authors: V
authors: Balasso
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Maria Jesús
authors: MJ
authors: Quintana
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Teresa
authors: T
authors: Puig
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Ignasi
authors: I
authors: Bolibar
authors: Clinical Epidemiology and Public Health, Institute of Biomedical Research (IIB Sant Pau)-Iberoamerican Cochrane Centre, Barcelona, Spain.|CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Facultat de Medicina, Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: Gerard
authors: G
authors: Urrútia
authors: CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Unidad de Bioestadística Clínica, Hospital Universitario Ramón y Cajal, IRYCIS, Madrid, Spain.
authors: Javier
authors: J
authors: Zamora
authors: CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Unidad de Epidemiología Clínica, Hospital Universitario Donostia, BioDonostia, San Sebastian, Spain.
authors: José Ignacio
authors: JI
authors: Emparanza
authors: CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Unidad de Investigación Clínica, Hospital Universitario 12 de Octubre, Madrid, Spain.
authors: Agustín
authors: A
authors: Gómez de la Cámara
authors: CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.|Departmento de Cardiología, Hospital Universitari Vall d'Hebron, Barcelona, Spain.|Vall d'Hebron Institut de Recerca (VHIR), Barcelona, Spain.
authors: Ignacio
authors: I
authors: Ferreira-González
mesh_terms: D016208:Databases, Factual; D003657:Decision Making; D003695:Delivery of Health Care; D006296:Health Services; D006801:Humans; D012189:Retrospective Studies; D064878:Web Browser