title: Prevalence and clinical characteristics of psoriasis in spondyloarthritis: a descriptive analysis of 275 patients.
abstract: OBJECTIVE
  To assess the prevalence of psoriasis among a cohort of patients with spondyloarthritis (SpA), to describe the clinical characteristics of psoriasis and associations with other manifestations.
  
  
  METHODS
  This is a retrospective single-centre observational study. The patients were diagnosed with definite SpA (expert opinion), either axial or peripheral. Each patient underwent a direct interview by a physician. The data regarding history of psoriasis and its clinical characteristics were collected. Univariate and multivariate analyses of patients with versus without psoriasis were carried out.
  
  
  RESULTS
  In all, 275 SpA patients were assessed: mean disease duration 16.7±11.8 years, 61.4% were men, 69.1% were diagnosed as axial SpA and 17.8% as peripheral SpA. In all, 84 patients (30.5%) had present or past psoriasis. The prevalence of psoriasis was high whatever the clinical presentation. Psoriasis was present before or concomitantly to diagnosis of SpA in 59/84 patients (70.2%). The most common types of psoriasis were plaque (66.7% of patients with psoriasis) and scalp psoriasis (65.5%). Other localisations were not rare, including palmoplantar pustulosis (20.2%) or nail psoriasis (19.1%). Patients with versus without psoriasis differed only through a lower proportion of radiological sacroiliitis (57.5% vs. 81.3 %, p<0.001).
  
  
  CONCLUSIONS
  With a prevalence of 30.5%, i.e. ten times higher than in the general population, this study confirms that psoriasis is a frequent and early manifestation in SpA and that a systematic search for psoriasis (e.g. scalp) is relevant in SpA for clinical practice, whatever the clinical presentation of SpA.
authors: Descartes Univ., Medicine Faculty; APHP, Rheumatology B Dept., Cochin Hosp., Paris; & Sorbonne Univ., UPMC Univ Paris 06, GRC-08, Inst. P. Louis d'Epidémiologie et de Santé Publique, Paris; Pitié-Salpétrière Hosp., AP-HP, Rheumatology Dept., Paris, France.
authors: Fanny
authors: F
authors: Roure
authors: Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
authors: Muriel
authors: M
authors: Elhai
authors: Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
authors: Vincent
authors: V
authors: Burki
authors: Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
authors: Isabelle
authors: I
authors: Fabreguet
authors: Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
authors: Eugénie
authors: E
authors: Koumakis
authors: Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
authors: Judith
authors: J
authors: Payet
authors: Paris Descartes University, Medicine Faculty; APHP, Rheumatology B Department, Cochin Hospital, Paris, France.
authors: Maxime
authors: M
authors: Dougados
authors: Sorbonne Universités, UPMC Univ Paris 06, GRC-08, Institut Pierre Louis d'Epidémiologie et de Santé Publique, Paris; Pitié-Salpétrière Hospital, AP-HP, Rheumatology Department, Paris, France.
authors: Laure
authors: L
authors: Gossec
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D018450:Disease Progression; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010297:Paris / Q000453:epidemiology; D015995:Prevalence; D011379:Prognosis; D011565:Psoriasis / Q000175:diagnosis / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D025242:Spondylarthropathies / Q000175:diagnosis / Q000453:epidemiology*; D013997:Time Factors