title: [Association between sleep duration and stroke in adults].
abstract: OBJECTIVE
  To explore the association between sleep duration and stroke in adults.
  
  
  METHODS
  Baseline data of 57 704 subjects who were aged 30-79 years and enrolled into China Kadoorie Biobank (CKB) study from Tongxiang county, Zhejiang province were analyzed. Multiple logistic regression analysis was conducted to investigate the putative association between sleep duration and stroke after adjusting for potential confounders.
  
  
  RESULTS
  The mean age of the subjects was (53.15 ± 10.20) years in males and (51.72 ± .69) years in females, respectively. There were 14.43% of males and 15.30% of females reporting sleep durations ≤ 6 hours per day and 5.39% of males and 5.95% of females reporting long duration of sleep (≥ 10 hours per day). The prevalence of stroke was 0.92% in males compared with 0.44% in females. The prevalence of stroke showed a U-shaped distribution with sleep duration. Compared with 7 hours sleep duration per day, long sleep duration (≥ 10 hours per day) was associated with stroke. The odds ratios (OR) were 2.11 (95%CI: 1.32-3.37) for males and 2.13 (95%CI: 1.24-3.65) for females after adjusting for age, socioeconomic status, health behaviors and health status. No statistical significant association was found between short sleep duration and stroke. Meanwhile, frequent sleep snoring was found to be associated with stroke in females (OR=1.63, 95% CI: 1.11-2.40).
  
  
  CONCLUSIONS
  Longer sleep duration was found to be associated with higher risk of stroke in both males and females. Frequent sleep snoring would increase the risk of stroke in females.
authors: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors: Haibin
authors: H
authors: Wu
authors: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors: Hao
authors: H
authors: Wang
authors: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors: Ruying
authors: R
authors: Hu
authors: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors: Jieming
authors: J
authors: Zhong
authors: Tongxiang County Center for Disease Control and Prevention.
authors: Yijian
authors: Y
authors: Qian
authors: Tongxiang County Center for Disease Control and Prevention.
authors: Chunmei
authors: C
authors: Wang
authors: Tongxiang County Center for Disease Control and Prevention.
authors: Kaixu
authors: K
authors: Xie
authors: Tongxiang County Center for Disease Control and Prevention.
authors: Lingli
authors: L
authors: Chen
authors: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors: Weiwei
authors: W
authors: Gong
authors: Chinese Academy of Medical Sciences.
authors: Yu
authors: Y
authors: Guo
authors: Provincial Center for Disease Control and Prevention, Hangzhou 310051, China; Email: myu@cdc.zj.cn.
authors: Min
authors: M
authors: Yu
authors: University of Oxford, UK.
authors: Zhengming
authors: Z
authors: Chen
authors: Chinese Academy of Medical Sciences; School of Public Health, Peking University; Email: lmlee@pumc.edu.cn.
authors: Liming
authors: L
authors: Li
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012890:Sleep; D012913:Snoring; D020521:Stroke / Q000453:epidemiology*; D013997:Time Factors