title: [STRESS- AND GERO PROTECTIVE PROPERTIES OF 20-HYDROXYECDYSONE AND ITS DERIVATIVES].
abstract: The long-term stress protective effects have been revealed among newly synthesized 9α-hydroxy-5α-ecdysteroids via a short-term heat stress tests (housefly Musca domestica). An increase as well as a reduce of protective effects for synthesized compounds have been demonstrated in comparison with the reference ecdysteroid 20-hydroxyecdysone, which obtained from the juice of Serratula coronata. The interdependence between stress- and geroprotective properties of the test models with their genotypic features and the structure of ecdvsteroids has been established.
authors: R G
authors: RG
authors: Savchenko
authors: S A
authors: SA
authors: Kostyleva
authors: V N
authors: VN
authors: Odinokov
authors: T T
authors: TT
authors: Akhmetkireeva
authors: G V
authors: GV
authors: Benkovskaya
mesh_terms: D000375:Aging / Q000187:drug effects*; D000818:Animals; D004195:Disease Models, Animal; D004441:Ecdysterone / Q000494:pharmacology*; D018882:Heat Stress Disorders / Q000517:prevention & control*; D006793:Houseflies
chemical_list: D004441:Ecdysterone