title: Discriminating Properties of Alkali Metal Ions Towards the Constituents of Proteins and Nucleic Acids. Conclusions from Gas-Phase and Theoretical Studies.
abstract: Quantitative insight into the structures and thermodynamics of alkali metal cations interacting with biological molecules can be obtained from studies in the gas phase combined with theoretical work. In this chapter, the fundamentals of the experimental and theoretical techniques are first summarized and results for such work on complexes of alkali metal cations with amino acids, small peptides, and nucleobases are reviewed. Periodic trends in how these interactions vary as the alkali metal cations get heavier are highlighted.
authors: Department of Chemistry, Wayne State University, Detroit, MI, 48202, USA. mrodgers@chem.wayne.edu.
authors: Mary T
authors: MT
authors: Rodgers
authors: Department of Chemistry, University of Utah, Salt Lake City, UT, 84112, USA. armentrout@chem.utah.edu.
authors: Peter B
authors: PB
authors: Armentrout
mesh_terms: D000596:Amino Acids / Q000737:chemistry; D002412:Cations / Q000737:chemistry; D003198:Computer Simulation; D008672:Metals, Alkali / Q000737:chemistry*; D008956:Models, Chemical; D009696:Nucleic Acids / Q000737:chemistry*; D011506:Proteins / Q000737:chemistry*; D013816:Thermodynamics
chemical_list: D000596:Amino Acids; D002412:Cations; D008672:Metals, Alkali; D009696:Nucleic Acids; D011506:Proteins
keywords: Amino acids; Collision-induced dissociation; Infrared multiple photon dissociation; Nucleobases; Peptides