title: Microbes without Borders: Decompartmentalization of the Aging Gut.
abstract: The microbiota supports intestinal homeostasis in developing animals. With increased age, gut maintenance declines and microbes can stray from traditional zones, negatively impacting host health. In this issue of Cell Host & Microbe, Li et al. (2016) detail the mechanisms leading to the decline in intestinal health in aged flies.
authors: Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA.
authors: Erin S
authors: ES
authors: Keebaugh
authors: Department of Metabolism and Aging, The Scripps Research Institute, Jupiter, FL 33458, USA. Electronic address: wja@scripps.edu.
authors: William W
authors: WW
authors: Ja
mesh_terms: D000375:Aging; D000818:Animals; D041981:Gastrointestinal Tract; D006706:Homeostasis; D006801:Humans; D007422:Intestines; D064307:Microbiota