title: Double homozygous mutations (R275W and M432V) in the ParkinGene associated with late-onset Parkinson's disease.
authors: Division of Neurology, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
authors: Jonathan
authors: J
authors: Carr
authors: Centre for Applied Neurogenetics, Djavad Mowafhagian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
authors: Ilaria
authors: I
authors: Guella
authors: Centre for Applied Neurogenetics, Djavad Mowafhagian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
authors: Chelsea
authors: C
authors: Szu-Tu
authors: Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
authors: Sihaam
authors: S
authors: Boolay
authors: Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
authors: Brigitte
authors: B
authors: Glanzmann
authors: Centre for Applied Neurogenetics, Djavad Mowafhagian Centre for Brain Health, Department of Medical Genetics, University of British Columbia, Vancouver, British Columbia, Canada.
authors: Matthew J
authors: MJ
authors: Farrer
authors: Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.
authors: Soraya
authors: S
authors: Bardien
mesh_terms: D000368:Aged; D005260:Female; D020022:Genetic Predisposition to Disease; D006720:Homozygote; D006801:Humans; D000067562:Late Onset Disorders / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009154:Mutation / Q000235:genetics*; D010300:Parkinson Disease / Q000235:genetics*; D010375:Pedigree; D044767:Ubiquitin-Protein Ligases / Q000235:genetics*
chemical_list: D044767:Ubiquitin-Protein Ligases; C111567:parkin protein