title: Crosslinked dendronized polyols as a general approach to brighter and more stable fluorophores.
abstract: Fluorescent, aqueous-soluble, crosslinked dendronized polyols (CDPs) are obtained through a sequential process involving ring-opening metathesis polymerization (ROMP), intra-chain ring-closing metathesis (RCM), and hydrolysis. This general strategy improves the quantum yields (QYs), brightness, and photostability of five common fluorophores whose emission wavelengths cover 150 nm. Additionally, the availability of the polymeric fluorophore to the cytosomes opens the door to applications in bioimaging and intracellular delivery.
authors: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. sczimmer@illinois.edu.
authors: Ying
authors: Y
authors: Li
authors: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. sczimmer@illinois.edu.
authors: Yugang
authors: Y
authors: Bai
authors: Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
authors: Nan
authors: N
authors: Zheng
authors: Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
authors: Yang
authors: Y
authors: Liu
authors: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. sczimmer@illinois.edu.
authors: Gretchen A
authors: GA
authors: Vincil
authors: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. sczimmer@illinois.edu.
authors: Benjamin J
authors: BJ
authors: Pedretti
authors: Department of Materials Science and Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.
authors: Jianjun
authors: J
authors: Cheng
authors: Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA. sczimmer@illinois.edu.
authors: Steven C
authors: SC
authors: Zimmerman