title: [Meta-analysis on risk factors of multidrug resistant tuberculosis in China].
abstract: OBJECTIVE
  To synthetically evaluate the risk factors of multidrug resistant tuberculosis (MDR-TB) in China.
  
  
  METHODS
  Chinese databases (CNKI, Wanfang, SinoMed and VIP) and English database (PubMed) were used to collect studies on risk factors for MDR-TB from 1990 to 2013. Meanwhile, relevant studies were manually retrieved. According to the inclusion and exclusion criteria, studies were screened, data were extracted and quality assessed. A Meta-analysis was performed by using Stata 11.0 software.
  
  
  RESULTS
  Twenty five studies on the risk factors of MDR-TB were synthetically and quantitatively analyzed. The results of Meta-analysis showed that factors as: being Han ethnic group, history of tuberculosis treatment, pulmonary cavity, floating population, TB case contact history, regular medication, living in rural areas, and poor economy were associated with the incidence of MDR-TB, the pooled OR values were 3.12 (95%CI: 1.16-8.40) , 5.27 (95% CI:3.60-7.72) , 1.39 (95%CI:1.03-1.87) , 1.69 (95%CI: 1.07-2.68) , 4.34 (95%CI: 1.91-9.86) , 0.23 (95% CI: 0.16-0.35) , 1.86 (95% CI: 1.59-2.18) and 1.62 (95% CI: 1.34-1.96) , respectively.
  
  
  CONCLUSIONS
  Factors as: being Han ethnic group, history of tuberculosis treatment, pulmonary cavity, floating population, TB case contact history, living in rural areas and poor economy were considered to be at risk of MDR-TB while regular medication might be a protective factor to MDR-TB.
authors: Department of Epidemiology and Bio statistics, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors: Xiaonan
authors: X
authors: Cai
authors: Department of Epidemiology and Bio statistics, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors: Dandan
authors: D
authors: Zhang
authors: Wuhan Center for Disease Control and Prevention.
authors: Yaqiong
authors: Y
authors: Yan
authors: Department of Epidemiology and Bio statistics, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors: Dixin
authors: D
authors: Tan
authors: Department of Epidemiology and Bio statistics, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Email: xuyihua_6@hotmail.com.
authors: Yihua
authors: Y
authors: Xu
mesh_terms: D002681:China / Q000453:epidemiology; D006801:Humans; D012307:Risk Factors; D018088:Tuberculosis, Multidrug-Resistant / Q000453:epidemiology*