title: The Approach to Pseudomonas aeruginosa in Cystic Fibrosis.
abstract: There is a high prevalence of Pseudomonas aeruginosa in patients with cystic fibrosis and clear epidemiologic links between chronic infection and morbidity and mortality exist. Prevention and early identification of infection are critical, and stand to improve with the advent of new vaccines and laboratory methods. Once the organism is identified, a variety of treatment options are available. Aggressive use of antipseudomonal antibiotics is the standard of care for acute pulmonary exacerbations in cystic fibrosis, and providers must take into account specific patient characteristics when making treatment decisions related to antibiotic selection, route and duration of administration, and site of care.
authors: Department of Internal Medicine, Yale School of Medicine, 333 Cedar Street, PO Box 208086, New Haven, CT 06520-8086, USA; Department of Pediatrics, Yale School of Medicine, 333 Cedar Street, PO Box 208084, New Haven, CT 06520-8084, USA. Electronic address: jaideep.talwalkar@yale.edu.
authors: Jaideep S
authors: JS
authors: Talwalkar
authors: Department of Medical Sciences, Frank H Netter MD School of Medicine, Quinnipiac University, 275 Mount Carmel Avenue, Hamden, CT 06518, USA; Division of Infectious Diseases and Immunology, Connecticut Children's Medical Center, 282 Washington Street, Suite 2L, Hartford, CT 06106, USA.
authors: Thomas S
authors: TS
authors: Murray
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002908:Chronic Disease; D003550:Cystic Fibrosis / Q000150:complications / Q000453:epidemiology / Q000382:microbiology; D014943:Global Health; D006801:Humans; D009017:Morbidity / Q000639:trends; D011552:Pseudomonas Infections / Q000150:complications / Q000453:epidemiology / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000302:isolation & purification*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Cystic fibrosis; Eradication; Inhaled antibiotics; Pseudomonas aeruginosa; Pulmonary exacerbation