title: Early Morphokinetic Monitoring of Embryos after Intracytoplasmic Sperm Injection with Fresh Ejaculate Sperm in Nonmosaic Klinefelter Syndrome: A Different Presentation.
abstract: The patient was diagnosed with nonmosaic 47, XXY Klinefelter Syndrome with the AZF deletion absent and SRY+. The nonmosaic 47, XXY karyotype was confirmed on a skin biopsy chromosomal analysis. Using only ejaculate motile sperms, 11 oocytes underwent ICSI and were placed rapidly in a time lapse (Embryoscope ©) with a specific culture dish. Biopsies were performed on six embryos on the 3rd day, and numerical chromosomal abnormalities were observed using the FISH test before transfer. PGS results were normal in only two embryos with normal morphokinetics in the Embryoscope. For clinical confirmation of pregnancy, ultrasonographic examination was performed during the 7th week of pregnancy, and two gestational sacs and fetal heart beat were observed.
authors: Department of Obstetrics and Gynecology, Novafertil IVF Center, Meram Yeni Yol No. 75, Meram, 42090 Konya, Turkey.
authors: Ali Sami
authors: AS
authors: Gurbuz
authors: Department of Urology, Novafertil IVF Center and Konya Hospital, Meram Yeni Yol No. 75, Meram, 42090 Konya, Turkey.
authors: Ahmet
authors: A
authors: Salvarci
authors: Medicana Konya IVF Center, Medicana Konya Feritpaşa Mah., Gurz Sok. No. 1, Selçuklu, 42060 Konya, Turkey.
authors: Necati
authors: N
authors: Ozcimen
authors: Department of Medical Genetic, Meram Tip Faculty, Necmettin Erbakan Universıty, Yunus Emre Mah., Meram, 42060 Konya, Turkey.
authors: Ayse Gul
authors: AG
authors: Zamani