title: Chitosan based biocomposite scaffolds for bone tissue engineering.
abstract: The clinical demand for scaffolds and the diversity of available polymers provide freedom in the fabrication of scaffolds to achieve successful progress in bone tissue engineering (BTE). Chitosan (CS) has drawn much of the attention in recent years for its use as graft material either as alone or in a combination with other materials in BTE. The scaffolds should possess a number of properties like porosity, biocompatibility, water retention, protein adsorption, mechanical strength, biomineralization and biodegradability suited for BTE applications. In this review, CS and its properties, and the role of CS along with other polymeric and ceramic materials as scaffolds for bone tissue repair applications are highlighted.
authors: Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur, Tamil Nadu, India.
authors: S
authors: S
authors: Saravanan
authors: Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur, Tamil Nadu, India.
authors: R S
authors: RS
authors: Leena
authors: Department of Biotechnology, School of Bioengineering, SRM University, Kattankulathur, Tamil Nadu, India. Electronic address: selvamurugan.n@ktr.srmuniv.ac.in.
authors: N
authors: N
authors: Selvamurugan
mesh_terms: D000818:Animals; D001861:Bone Regeneration; D018786:Bone Substitutes / Q000737:chemistry*; D001842:Bone and Bones / Q000503:physiopathology; D002113:Calcification, Physiologic; D048271:Chitosan / Q000737:chemistry*; D006801:Humans; D055595:Mechanical Phenomena; D016062:Porosity; D044968:Regenerative Medicine; D023822:Tissue Engineering
chemical_list: D018786:Bone Substitutes; D048271:Chitosan
keywords: Biodegradability; Bone tissue engineering; Chitosan; Protein adsorption; Scaffold