title: Recurrence of ANCA-associated vasculitis in a patient with kidney trasplant.
abstract: Renal disease secondary to vasculitis associated with anti-neutrophil cytoplasmic antibodies (ANCA) can lead to chronic renal disease requiring renal replacement therapy. In these patients, kidney transplantation offers excellent long-term rates of allograft and patient survival; consequently, they can be trasplanted when the clinical disease activity has remitted. However, the risk of disease relapses in the renal allograft remains, although at lower rates due to modern immunosuppressive regimens. We describe the case of a male patient with extracapillary glomerulonephritis type III C-ANCA (+) who developed a recurrence in the renal allograft 8 years after transplantation. Intensive immunosupression with plasmapheresis controlled the disease.
authors: Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, España. Electronic address: Gcosmes@usal.es.
authors: Pedro
authors: P
authors: García Cosmes
authors: Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, España.
authors: Pilar
authors: P
authors: Fraile Gómez
authors: Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, España.
authors: Kamil
authors: K
authors: Lewczuk
authors: Servicio de Anatomía Patológica, Hospital Universitario de Salamanca, Salamanca, España.
authors: Marta
authors: M
authors: Rodríguez González
authors: Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, España.
authors: Elena
authors: E
authors: Ruiz Ferreras
authors: Servicio de Nefrología, Hospital Universitario de Salamanca, Salamanca, España.
authors: Guadalupe
authors: G
authors: Tabernero Fernández
mesh_terms: D056648:Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; D019268:Antibodies, Antineutrophil Cytoplasmic; D006801:Humans; D007668:Kidney; D007676:Kidney Failure, Chronic; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D012008:Recurrence; D014657:Vasculitis
chemical_list: D019268:Antibodies, Antineutrophil Cytoplasmic
keywords: Anti-neutrophil cytoplasmic antibodies-associated vasculitis; Kidney transplantation; Recidiva.; Relapse; Trasplante renal; Vasculitis asociada a anticuerpos anticitoplasma de neutrófilos