title: Tooth loss and metabolic syndrome in middle-aged Japanese adults.
abstract: Metabolic syndrome is associated with periodontal disease and dental caries; however, little attention has been given to the association between metabolic syndrome and tooth loss, which is the endpoint of these two diseases. This study examined this association in middle-aged adults over a 5-year period.
  
  
  
  A retrospective study was performed in 2107 participants (1718 males and 389 females) aged 35-60 years who underwent annual dental check-ups, to evaluate tooth loss and metabolic components, including obesity, elevated triglycerides, blood pressure, fasting glucose, and reduced high-density lipoprotein. Logistic regression analysis was performed to evaluate the association between metabolic syndrome (≥3 components) at the baseline examination and tooth loss.
  
  
  
  Over a 5-year period, 10.8% of the participants lost at least one tooth. Compared to those with no metabolic components, participants with ≥3 components had an increased risk of tooth loss (odds ratio = 1.54; 95% confidence interval: 1.01-2.37), adjusting for age, gender, dental caries experience, attachment loss, oral hygiene status, number of teeth, tooth brushing frequency, smoking, and occupational status.
  
  
  
  Metabolic syndrome was associated with the incidence of tooth loss among middle-aged adults.
authors: Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan.
authors: Michiko
authors: M
authors: Furuta
authors: Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan.
authors: An
authors: A
authors: Liu
authors: Heisei Yokohama Hospital, Yokohama, Japan.
authors: Takashi
authors: T
authors: Shinagawa
authors: Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan.
authors: Kenji
authors: K
authors: Takeuchi
authors: Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan.
authors: Toru
authors: T
authors: Takeshita
authors: Department of Preventive Dentistry and Dental Public Health, School of Dentistry, Aichi-Gakuin University, Nagoya, Japan.
authors: Yoshihiro
authors: Y
authors: Shimazaki
authors: Section of Preventive and Public Health Dentistry, Division of Oral Health, Growth and Development, Kyushu University Faculty of Dental Science, Fukuoka, Japan.
authors: Yoshihisa
authors: Y
authors: Yamashita
mesh_terms: D000328:Adult; D003731:Dental Caries; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome; D008875:Middle Aged; D010510:Periodontal Diseases; D012189:Retrospective Studies; D016388:Tooth Loss
keywords: dental caries; metabolic syndrome; middle aged; periodontal disease; tooth loss