title: [EXTRACORPOREAL BLOOD CORRECTION METHODS AND THEIR IMPACT ON PRODUCTS OF MICROBIAL METABOLISM IN PATIENTS WITH SEPSIS].
abstract: Sepsis is a disease with a high death-rate and is accompanied by profound metabolic disturbances. Interference of microbe metabolic products with biochemical processes in human organism is present in case of severe infection. But there is little information about integration of microbe and human metabolism in septic patients. We evaluated an indol level in healthy individuals and septic patients. It was revealed that septic patients have higher indol levels. Hemoperfusion through "Ovosorb" sorbing agent allows to decrease indol concentration to normal levels. Application of hemosorbtion in combination with magnetic blood processing allows achieving faster and more effective indol removal.
authors: R E
authors: RE
authors: Yakubchevich
authors: V A
authors: VA
authors: Predko
authors: V V
authors: VV
authors: Spas
authors: S A
authors: SA
authors: Savostianik
mesh_terms: D018806:APACHE; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006464:Hemoperfusion / Q000379:methods*; D006801:Humans; D007211:Indoles / Q000097:blood*; D053208:Kaplan-Meier Estimate; D055909:Magnetic Field Therapy / Q000379:methods*; D008875:Middle Aged; D010059:Ovomucin / Q000008:administration & dosage*; D018805:Sepsis / Q000097:blood / Q000382:microbiology* / Q000401:mortality / Q000628:therapy*; D055815:Young Adult
chemical_list: D007211:Indoles; C073841:Ovosorb; D010059:Ovomucin; C030374:indole