title: Value, but high costs in post-deposition data curation.
abstract: Discoverability of sequence data in primary data archives is proportional to the richness of contextual information associated with the data. Here, we describe an exercise in the improvement of contextual information surrounding sample records associated with metagenomics sequence reads available in the European Nucleotide Archive. We outline the annotation process and summarize findings of this effort aimed at increasing usability of publicly available environmental data. Furthermore, we emphasize the benefits of such an exercise and detail its costs. We conclude that such a third party annotation approach is expensive and has value as an element of curation, but should form only part of a more sustainable submitter-driven approach. Database URL: http://www.ebi.ac.uk/ena.
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK petra@ebi.ac.uk.
authors: Petra
authors: P
authors: ten Hoopen
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors: Clara
authors: C
authors: Amid
authors: Alfred-Wegener-Institut Helmholtz-Zentrum für Polar-und Meeresforschung, Am Handelshafen 12, Bremerhaven 27570, Germany.
authors: Pier Luigi
authors: PL
authors: Buttigieg
authors: Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, Heraklion, Crete, P.O. Box 2214 71003, Greece.
authors: Evangelos
authors: E
authors: Pafilis
authors: Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, Heraklion, Crete, P.O. Box 2214 71003, Greece.
authors: Panos
authors: P
authors: Bravakos
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors: Ana M
authors: AM
authors: Cerdeño-Tárraga
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors: Richard
authors: R
authors: Gibson
authors: CSIRO Marine and Atmospheric Research, Castray Esplanade, Hobart TAS 7001, Australia.
authors: Tim
authors: T
authors: Kahlke
authors: Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, Heraklion, Crete, P.O. Box 2214 71003, Greece.
authors: Aglaia
authors: A
authors: Legaki
authors: Pondicherry University, Brookshabad Campus, Andaman and Nicobar Islands, Port Blair 744112, India.
authors: Kada
authors: K
authors: Narayana Murthy
authors: Institute of Marine Biology, Biotechnology and Aquaculture, Hellenic Centre for Marine Research, Heraklion, Crete, P.O. Box 2214 71003, Greece.
authors: Gabriella
authors: G
authors: Papastefanou
authors: Max Planck Institute for Marine Microbial Ecology, Microbial Genomics and Bioinformatics Group, Celsiusstr. 1, Bremen 28359, Germany.
authors: Emiliano
authors: E
authors: Pereira
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors: Marc
authors: M
authors: Rossello
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors: Ana
authors: A
authors: Luisa Toribio
authors: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, UK.
authors: Guy
authors: G
authors: Cochrane
mesh_terms: D019295:Computational Biology / Q000191:economics*; D003625:Data Collection; D030561:Databases, Nucleic Acid / Q000191:economics*; D017753:Ecosystem; D005060:Europe; D005843:Geography; D006801:Humans; D056186:Metagenomics; D064307:Microbiota; D058977:Molecular Sequence Annotation; D012660:Semantics; D017421:Sequence Analysis