title: Assessment of nasal mucociliary activity in patients with Behçet's disease.
abstract: OBJECTIVE
  To investigate nasal mucociliary clearance in patients with Behçet's disease.
  
  
  METHODS
  Thirty patients with Behçet's disease, diagnosed on the basis of criteria defined by the International Study Group for Behçet's Disease, and 30 healthy individuals were recruited. In both groups, individuals with conditions that could affect nasal mucociliary clearance were excluded. Nasal mucociliary clearance time was evaluated using saccharin tests. The time between placement of a saccharin tablet and the tasting of the saccharin was measured and recorded as the saccharin clearance time.
  
  
  RESULTS
  The mean nasal mucociliary clearance time was significantly longer in the Behçet's disease patients than in the control subjects (p < 0.001). Furthermore, there was a positive correlation between Behçet's disease duration and nasal mucociliary clearance time (p < 0.001, r = 0.882).
  
  
  CONCLUSIONS
  The results suggest that nasal mucociliary clearance time is longer in Behçet's disease patients than in control subjects, and is positively correlated with disease duration.
authors: Department of ORL,Dumlupinar University,Kutahya,Turkey.
authors: I
authors: I
authors: Ozbay
authors: Department of ORL,Dumlupinar University,Kutahya,Turkey.
authors: C
authors: C
authors: Kucur
authors: Department of Physical Therapy and Rehabilitation,Dumlupinar University,Kutahya,Turkey.
authors: F
authors: F
authors: Temİzturk
authors: Department of Physical Therapy and Rehabilitation,Dumlupinar University,Kutahya,Turkey.
authors: Y
authors: Y
authors: Ozkan
authors: Department of Internal Medicine,Dumlupinar University,Kutahya,Turkey.
authors: C
authors: C
authors: Kahraman
authors: Department of ORL,Dumlupinar University,Kutahya,Turkey.
authors: F
authors: F
authors: Oghan
mesh_terms: D000328:Adult; D000368:Aged; D001528:Behcet Syndrome / Q000503:physiopathology*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D009079:Mucociliary Clearance / Q000502:physiology*; D009297:Nasal Mucosa / Q000503:physiopathology*; D012439:Saccharin; D013997:Time Factors; D055815:Young Adult
chemical_list: D012439:Saccharin
keywords: Behçet Disease; Nasal Mucosa; Saccharin