title: Stationary facial nerve paresis after surgery for recurrent parotid pleomorphic adenoma: a follow-up study of 219 cases in Denmark in the period 1985-2012.
abstract: The purpose was to assess degree of permanent facial nerve dysfunction after surgery for recurrent pleomorphic adenoma (RPA) of the parotid gland, including variables that might influence re-operation outcomes. Nationwide retrospective longitudinal cohort study including a questionnaire survey of patients undergoing surgery for RPA. Of 219 living patients, 198 (92 %) responded and 127 (63 %) reported no facial dysfunction. Statistically significant associations were found between number of surgeries and permanent facial nerve dysfunction of all degrees (OR 1.43, 95 % CI 1.16-1.78, p = 0.001). A not significant tendency for females to be associated with worse outcome was found (p = 0.073). Risks of different degrees of paresis after the second-fourth surgeries were found (OR 1.86-2.19, p < 0.05). Our study demonstrates a significant correlation between number of surgeries for RPA of the parotid and severity of facial nerve paresis. This is important when informing and planning treatment of these patients.
authors: Department of Otolaryngology, Head and Neck Surgery 2073, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark. andersnoehr@gmail.com.
authors: Anders
authors: http://orcid.org/0000-0001-6316-9303
authors: A
authors: Nøhr
authors: Department of Otolaryngology, Head and Neck Surgery 2073, Rigshospitalet, University Hospital of Copenhagen, Blegdamsvej 9, 2100, Copenhagen Ø, Denmark.|Department of Otorhinolaryngology and Maxillofacial Surgery, Køge University Hospital, Lykkebækvej 1, 4600, Køge, Denmark.|Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, 2200, Copenhagen, Denmark.
authors: Simon
authors: S
authors: Andreasen
authors: Department of Pathology, Rigshospitalet, Blegdamsvej 9, 2100, Copenhagen, Denmark.
authors: Marianne Hamilton
authors: MH
authors: Therkildsen
authors: Department of Otorhinolaryngology and Maxillofacial Surgery, Køge University Hospital, Lykkebækvej 1, 4600, Køge, Denmark.|Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3b, 2200, Copenhagen, Denmark.
authors: Preben
authors: P
authors: Homøe
mesh_terms: D008949:Adenoma, Pleomorphic / Q000473:pathology / Q000601:surgery; D000328:Adult; D000368:Aged; D003718:Denmark / Q000453:epidemiology; D005154:Facial Nerve / Q000503:physiopathology*; D005158:Facial Paralysis / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery; D010306:Parotid Gland / Q000473:pathology / Q000601:surgery; D010307:Parotid Neoplasms / Q000473:pathology / Q000601:surgery; D011183:Postoperative Complications / Q000453:epidemiology / Q000503:physiopathology; D012086:Reoperation / Q000009:adverse effects / Q000379:methods / Q000706:statistics & numerical data; D012189:Retrospective Studies; D012468:Salivary Gland Neoplasms / Q000473:pathology / Q000601:surgery
keywords: Facial nerve paresis; Morbidity; Pleomorphic adenoma; Recurrence; Surgery