title: Synthesis of Pyrido-Fused Quinazolinone Derivatives via Copper-Catalyzed Domino Reaction.
abstract: A simple and efficient synthesis of 11H-pyrido[2,1-b]quinazolin-11-ones by Cu(OAc)2·H2O-catalyzed reaction of easily available substituted isatins and 2-bromopyridine derivatives has been developed. The reaction involves C-N/C-C bond cleavage and two C-N bond formations in a one-pot operation. This methodology is complementary to previously reported synthetic procedures, and two plausible reaction mechanisms are discussed.
authors: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors: Meilin
authors: M
authors: Liu
authors: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors: Miaomiao
authors: M
authors: Shu
authors: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors: Chaochao
authors: C
authors: Yao
authors: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors: Guodong
authors: G
authors: Yin
authors: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors: Dunjia
authors: D
authors: Wang
authors: Hubei Collaborative Innovation Center for Rare Metal Chemistry, Hubei Key Laboratory of Pollutant Analysis and Reuse Technology, Hubei Normal University , Huangshi 435002, People's Republic of China.
authors: Jinkun
authors: J
authors: Huang