title: Pituitary pars intermedia dysfunction (equine Cushing's disease) in a Thoroughbred stallion: a single report.
abstract: Equine pituitary pars intermedia dysfunction (PPID) generally occurs in older horses showing hirsutism, delayed molting, weight loss, polydipsia, polyuria, laminitis, and reproductive disorders (in broodmares), but there have been no reports on stallions. This report presents a case of a 21-year-old Thoroughbred stallion that developed hirsutism and experienced delayed molting. There were no abnormal findings for semen quality or the stallion's sexual desire. The horse was diagnosed with PPID based on dexamethasone suppression test and plasma levels of adrenocorticotropic hormone. It was then medicated with pergolide mesylate. Since the horse died due to humerus fracture, an autopsy was conducted, and pituitary adenoma was confirmed. No pathological findings were defined in the testicles; therefore, reproductive activity might not have been impaired.
authors: Kyushu Stallion Station, The Japan Bloodhorse Breeders' Association, Kagoshima 899-8313, Japan.
authors: Takashi
authors: T
authors: Hatazoe
authors: Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan.
authors: Hiroaki
authors: H
authors: Kawaguchi
authors: Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan.
authors: Seiji
authors: S
authors: Hobo
authors: Joint Faculty of Veterinary Medicine, Kagoshima University, Kagoshima 890-0065, Japan.
authors: Kazuhiro
authors: K
authors: Misumi
keywords: Thoroughbred; hirsutism; pituitary pars intermedia dysfunction; stallion