title: Three-Dimensional Kinematic Analysis of Prehension Movements in Young Children with Autism Spectrum Disorder: New Insights on Motor Impairment.
abstract: The study was aimed at better clarifying whether action execution impairment in autism depends mainly on disruptions either in feedforward mechanisms or in feedback-based control processes supporting motor execution. To this purpose, we analyzed prehension movement kinematics in 4- and 5-year-old children with autism and in peers with typical development. Statistical analysis showed that the kinematics of the grasp component was spared in autism, whereas early kinematics of the reach component was atypical. We discussed this evidence as suggesting impairment in the feedforward processes involved in action execution, whereas impairment in feedback-based control processes remained unclear. We proposed that certain motor abilities are available in autism, and children may use them differently as a function of motor context complexity.
authors: Child Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, Via Don Luigi Monza 20, 23842, Bosisio Parini, Lecco, Italy. cristina.campione@bp.lnf.it.
authors: Giovanna Cristina
authors: http://orcid.org/0000-0003-0410-5400
authors: GC
authors: Campione
authors: Bioingineering Lab, Scientific Institute, IRCCS Eugenio Medea, Via Don Luigi Monza 20, 23842, Bosisio Parini, Lecco, Italy.|Department of Electronics Information and Bioengineering (DEIB), Politecnico di Milano, Via Ponzio 34, 20133, Milan, Italy.
authors: Caterina
authors: C
authors: Piazza
authors: Child Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, Via Don Luigi Monza 20, 23842, Bosisio Parini, Lecco, Italy.
authors: Laura
authors: L
authors: Villa
authors: Child Psychopathology Unit, Scientific Institute, IRCCS Eugenio Medea, Via Don Luigi Monza 20, 23842, Bosisio Parini, Lecco, Italy.
authors: Massimo
authors: M
authors: Molteni
mesh_terms: D000067877:Autism Spectrum Disorder / Q000503:physiopathology*; D001696:Biomechanical Phenomena / Q000502:physiology; D002675:Child, Preschool; D025461:Feedback, Physiological / Q000502:physiology; D005260:Female; D018737:Hand Strength / Q000502:physiology*; D006801:Humans; D008297:Male; D009068:Movement / Q000502:physiology*; D011597:Psychomotor Performance / Q000502:physiology
keywords: Autism-spectrum-disorder; Feedforward; Grasping; Kinematics; Reaching; Sensory-control-feedback