title: Evaluation of maternal and perinatal outcomes among overweight women who experienced stillbirth.
abstract: OBJECTIVE
  To investigate associations between overweight and adverse clinical outcomes among women who experienced stillbirth.
  
  
  METHODS
  234 pregnant women (stillbirth group, n = 115; live birth group, n = 119) were included in this retrospective case-control study. Recorded risk factors were age, gravidity, parity, gestational weeks, fetal birth weight, gestational diabetes mellitus (GDM), preeclampsia (PE), intrauterine growth restriction (IUGR), levels of prenatal test markers (alpha-fetoprotein (AFP), pregnancy-associated plasma protein, human chorionic gonadotropin (β-hCG) and E3) and body mass index (BMI).
  
  
  RESULTS
  Statistically significant differences were observed between the groups in terms of birth weight, IUGR, GDM, PE, AFP level, β-hCG level, maternal E3 level and BMI (p < 0.05). Subgroup analyses revealed that 34 and 81 patients in the stillbirth group were of normal weight and overweight, respectively, fetal birth weight, IUGR, GDM, PE, AFP level, β-hCG level and E3 level differed significantly between these subgroups and the live birth group (p < 0.05).
  
  
  CONCLUSIONS
  Women who experience stillbirth tend to be more overweight than those who experience live birth. Additionally, IUGR, GDM and PE are more common among overweight women. Therefore, overweight women should be encouraged to lose weight before pregnancy. If they become pregnant without losing weight, they should be followed up closely to avoid adverse perinatal outcomes.
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Mehmet
authors: M
authors: Çınar
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Hakan
authors: H
authors: Timur
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Rıfat Taner
authors: RT
authors: Aksoy
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Ali İrfan
authors: Aİ
authors: Güzel
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Aytekin
authors: A
authors: Tokmak
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Rahime
authors: R
authors: Bedir Fındık
authors: a Department of Obstetrics and Gynecology , Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey.
authors: Dilek
authors: D
authors: Uygur
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000378:metabolism; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008875:Middle Aged; D050177:Overweight / Q000150:complications* / Q000378:metabolism; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology / Q000378:metabolism; D012189:Retrospective Studies; D012307:Risk Factors; D050497:Stillbirth; D055815:Young Adult
chemical_list: D015415:Biomarkers
keywords: Obesity; overweight pregnancy; prenatal test markers; stillbirth