title: Management of Root Resorption Using Chemical Agents: A Review.
abstract: Root resorption (RR) is defined as the loss of dental hard tissues because of clastic activity inside or outside of tooth the root. In the permanent dentition, RR is a pathologic event; if untreated, it might result in the premature loss of the affected tooth. Several hypotheses have been suggested as the mechanisms of root resorption such as absence of the remnants of Hertwig's epithelial root sheath (HERS) and the absence of some intrinsic factors in cementum and predentin such as amelogenin or osteoprotegerin (OPG). It seems that a barrier is formed by the less-calcified intermediate cementum or the cementodentin junction that prevents external RR. There are several chemical strategies to manage root resorption. The purpose of this paper was to review several chemical agents to manage RR such as tetracycline, sodium hypochlorite, acids (citric acid, phosphoric acid, ascorbic acid and hydrochloric acid), acetazolamide, calcitonin, alendronate, fluoride, Ledermix and Emdogain.
authors: Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Shaheed Beheshti University of Medical Sciences, and Iranian National Elite Foundation, Tehran, Iran.
authors: Zahed
authors: Z
authors: Mohammadi
authors: Department of Pediatric Dentistry, Faculty of Dentistry, Hacettepe University, Ankara, Turkey.
authors: Zafer
authors: Z
authors: C Cehreli
authors: Private Practitioner, Hamedan, Iran.
authors: Sousan
authors: S
authors: Shalavi
authors: Department of Periodontology, Endodontology, Pharmacology and Microbiology, Dental School, University of Brescia, Italy.
authors: Luciano
authors: L
authors: Giardino
authors: Department of Odontostomatological and Maxillofacial Sciences, Federico II University of Naples, Italy.
authors: Flavio
authors: F
authors: Palazzi
authors: Iranian Center for Endodontic Research, Research Institute of Dental Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors: Saeed
authors: S
authors: Asgary
keywords: Alendronate; Calcitonin; Citric Acid; Emdogain; Fluoride; Osteoclast; Root Resorption; Tetracycline