title: [CHANGING OF THE MORPHOMETRIC AND CYTOLOGICAL INDEXES OF THE SPLEEN IN THE CONDITION OF ACUTE BLOOD LOSS ON THE BACKGROUND OF STEM CELLS INSERTION].
abstract: The objective of the work was to study morphometric and cytological indexes of the spleen in mature and old laboratory animals after acute blood loss on the background of allogenic transplantation of placenta MMSC and GSC. The study proved that 5 days after acute blood loss on the background of stem cells transplantations to the mature animals there was a reduction of lymphoid follicles area due to reduction in thymus independent area. There were no immunosuppressive effects to the white pulp of the spleen in old animals. The increase of leucocytes' and erythrocytes' elements in red pulp in the mature animals was noted. In old animals, the increase of cells' density in red pulp is mainly due to increased number of erythroid cells.
authors: I Yu
authors: IY
authors: Maklakova
authors: A P
authors: AP
authors: Yastrebov
authors: D Yu
authors: DY
authors: Grebnev
mesh_terms: D000208:Acute Disease; D000818:Animals; D002452:Cell Count; D004195:Disease Models, Animal; D018380:Hematopoietic Stem Cell Transplantation; D006470:Hemorrhage / Q000473:pathology* / Q000628:therapy; D007108:Immune Tolerance; D008297:Male; D051379:Mice; D013154:Spleen / Q000276:immunology / Q000473:pathology*