title: Serum heart type fatty acid binding protein levels are not changed in hyperthyroidism.
abstract: BACKGROUND
  Heart type fatty acid binding protein (H-FABP) is a small protein and released into the circulation when myocardial damage has occurred. Previous studies have demonstrated that H-FABP is closely associated with cardiac and some endocrinologic disorders including prediabetes, metabolic syndrome, and acromegaly. Hyperthyroism is a well-known disorder associated with cardiovascular diseases. We aimed to investigate the effect of hyperthyrodism on H-FABP levels.
  
  
  METHODS
  Forty six patients with hyperthyroidism with no known history of coronary artery disease and 40 healthy controls are involved in the study. Serum H-FABP levels are measured using sandwich enzyme-linked immunosorbent assay.
  
  
  RESULTS
  There was no significant difference between serum H-FABP levels of patients with hyperthyroidism and controls (871±66 pg/mL, and 816±66 pg/mL, respectively P=0.56). There was no significant correlation between H-FABP, free triiodothyronine (fT3), free thyroxine (fT4), and thyroid stimulating hormone (TSH) levels in patients and controls.
  
  
  CONCLUSIONS
  Serum H-FABP levels are not altered in patients with hyperthyroidism.
authors: Department of Endocrinology and Metabolism, Diskapi Teaching and Research Hospital, Ankara, Turkey - mustafaozbek10@hotmail.com.
authors: Mustafa
authors: M
authors: Ozbek
authors: Askin
authors: A
authors: Gungunes
authors: Mustafa
authors: M
authors: Sahin
authors: Zeynep
authors: Z
authors: Ginis
authors: Bekir
authors: B
authors: Ucan
authors: Muyesser
authors: M
authors: Sayki
authors: Esra
authors: E
authors: Tutal
authors: Erman
authors: E
authors: Cakal
authors: Serife M
authors: SM
authors: Kuşkonmaz
authors: Mehmet A
authors: MA
authors: Öztürk
authors: Tuncay
authors: T
authors: Delibasi
mesh_terms: D000328:Adult; D004797:Enzyme-Linked Immunosorbent Assay; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins / Q000097:blood*; D005260:Female; D006801:Humans; D006980:Hyperthyroidism / Q000097:blood*; D008297:Male; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood; D014284:Triiodothyronine / Q000097:blood
chemical_list: C493408:FABP3 protein, human; D000074026:Fatty Acid Binding Protein 3; D050556:Fatty Acid-Binding Proteins; D014284:Triiodothyronine; D013972:Thyrotropin; D013974:Thyroxine