title: Malperfusion syndromes in aortic dissections.
abstract: Aortic dissection remains a challenging clinical scenario, especially when complicated by peripheral malperfusion. Improvements in medical imaging have furthered understanding of the pathophysiology of malperfusion events in association with aortic dissection, including the elucidation of different mechanisms of branch vessel obstruction. Despite these advances, malperfusion syndrome remains a deadly entity with significant mortality. This review presents the latest knowledge regarding the pathogenesis of aortic dissection complicated by malperfusion syndrome, and discusses the diagnostic and therapeutic guidelines for management of this vicious entity.
authors: Johns Hopkins Hospital, Department of Surgery, Baltimore, MD, USA.
authors: Todd C
authors: TC
authors: Crawford
authors: Johns Hopkins Hospital, Department of Surgery, Baltimore, MD, USA rbeauli1@jhmi.edu.
authors: Robert J
authors: RJ
authors: Beaulieu
authors: Johns Hopkins Hospital, Department of Surgery, Baltimore, MD, USA.
authors: Bryan A
authors: BA
authors: Ehlert
authors: Johns Hopkins Hospital, Center for Vascular Medicine, Baltimore, MD, USA.
authors: Elizabeth V
authors: EV
authors: Ratchford
authors: Johns Hopkins Hospital, Department of Surgery, Baltimore, MD, USA.
authors: James H
authors: JH
authors: Black
mesh_terms: D000784:Aortic Dissection / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D000818:Animals; D001014:Aortic Aneurysm / Q000150:complications* / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000628:therapy; D001027:Aortography; D001807:Blood Vessel Prosthesis; D019917:Blood Vessel Prosthesis Implantation / Q000295:instrumentation; D057510:Endovascular Procedures / Q000295:instrumentation; D006439:Hemodynamics; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D012039:Regional Blood Flow; D015607:Stents; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color; D014654:Vascular Patency
keywords: aortic diseases; minimally invasive; practice guidelines; stents; surgical procedures