title: Synthesis of novel ICIE16/BSG and ICIE16/BSG-NITRI bioglasses and description of ionic release kinetics upon immersion in SBF fluid: Effect of nitridation.
abstract: A novel bioactive glass scaffold ICIE16/BSG has been prepared from a mixture of two different melt-derived glasses: a silicate bioglass (ICIE16) and a borosilicate bioglass (BSG). Combined processing techniques (gel casting and foam replication) were used to form three-dimensional, interconnected porous monolith scaffolds (Orgaz et al., 2016) [1]. They were then nitrided with a hot ammonia flow as described in (Aleixandre et al., 1973) [3] and (Nieto, 1984) [4] to synthesize the ICIE16/BSG-NITRI bioglass (Orgaz et al., 2016) [1]. Herein we present a flow chart summarizing the forming process, plus images of the resulting scaffold after sintering and drying. Bioactivity was characterized in vitro by immersion in simulated body fluid (SBF) for up to seven days. Data of ionic release kinetics upon SBF immersion are presented.
authors: Instituto de Cerámica y Vidrio, Consejo Superior de Investigaciones Científicas (ICV-CSIC), c/Kelsen no. 5, 28049 Madrid, Spain.
authors: Felipe
authors: F
authors: Orgaz
authors: Universidad de Málaga, Departamento de Anatomía y Medicina Legal, Facultad de Medicina, Campus de Teatinos, 29071 Málaga, Spain; Centro de Investigación Biomédica en Red, Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, c/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, Spain.
authors: Daniel
authors: D
authors: Amat
authors: Instituto de Cerámica y Vidrio, Consejo Superior de Investigaciones Científicas (ICV-CSIC), c/Kelsen no. 5, 28049 Madrid, Spain.
authors: Olga
authors: O
authors: Szycht
authors: Instituto de Cerámica y Vidrio, Consejo Superior de Investigaciones Científicas (ICV-CSIC), c/Kelsen no. 5, 28049 Madrid, Spain.
authors: Aleksandra
authors: A
authors: Dzika
authors: Instituto de Cerámica y Vidrio, Consejo Superior de Investigaciones Científicas (ICV-CSIC), c/Kelsen no. 5, 28049 Madrid, Spain.
authors: Flora
authors: F
authors: Barba
authors: Universidad de Málaga & IBIMA, Departamento de Biología Celular, Genética y Fisiología, Facultad de Ciencias, Campus de Teatinos, 29071 Málaga, Spain; Centro de Investigación Biomédica en Red, Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, c/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, Spain; BIONAND-Universidad de Málaga, c/Severo Ochoa 35, Campanillas, 29590 Málaga, Spain.
authors: José
authors: J
authors: Becerra
authors: Centro de Investigación Biomédica en Red, Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Instituto de Salud Carlos III, c/Monforte de Lemos 3-5, Pabellón 11, Planta 0, 28029 Madrid, Spain; BIONAND-Universidad de Málaga, c/Severo Ochoa 35, Campanillas, 29590 Málaga, Spain; Universidad de Málaga & IBIMA, Departamento de Biología Celular, Genética y Fisiología, Facultad de Ciencias, Campus de Teatinos, 29071 Málaga, Spain.
authors: Leonor
authors: L
authors: Santos-Ruiz
keywords: Bioglass; Biomaterial resorption; Biomaterials; Bone repair; Degradability; Simulated body fluid