title: [Perinatal asphyxia and acute renal insufficiency in Ouagadougou].
abstract: OBJECTIVE
  This study aimed to analyze acute renal failure in perinatal asphyxia (PNA) of term newborns in a sub-Saharan urban health center.
  
  
  METHODS
  The study was prospective, conducted from 1st June to 30th November 2013 on term newborns hospitalized at the centre hospitalier universitaire pédiatrique Charles-de-Gaulle for PNA. Renal insufficiency (RI) was defined by a serum creatinine greater than or equal to 90 μmol/L.
  
  
  RESULTS
  Eighty-five PNA cases were included, or 19.8% of newborns hospitalized in the study period. The sex ratio was 2.1. Thirty-eight newborns (44.7%) had RI. Their creatinine averaged 153.8±96.6 μmol/L. Twenty-six of 38 (68.4%) had brain damage in Sarnat stage 2 and 12 (31.6%) stage 3. Twelve newborns with RI (31.6%) had seizures. Transfontanellar echography revealed an abnormality in 30 cases (78.9%) of RI. Of the 38 newborns with renal failure, albuminuria was found in 21 cases (65.2%) and leukocyturia in 28 cases (73.7%). Renal function improved in 86.1% of cases. Newborns with initially normal serum creatinine had no RI during hospitalization. Six newborns (7.1%) died.
  
  
  CONCLUSIONS
  This study showed that acute RI is common during PNA most particularly in newborns with severe neurological impairment. In our context, earlier support for women in labor could help prevent PNA and therefore newborn acute RI.
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Services de néphrologie et d'hémodialyse, centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso. Electronic address: coulibalygerard@hotmail.fr.
authors: G
authors: G
authors: Coulibaly
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: S O
authors: SO
authors: Ouédraogo-Yugbaré
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: F
authors: F
authors: Kouéta
authors: Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: L S
authors: LS
authors: Yao
authors: Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: H
authors: H
authors: Savadogo
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: L
authors: L
authors: Dao
authors: Service de néonatalogie, Fédération de pédiatrie, CHU, 49933 Angers cedex 9, France.
authors: B
authors: B
authors: Leboucher
authors: Service de néphrologie pédiatrique, Fédération de pédiatrie, CHU, 49933 Angers cedex 9, France.
authors: G
authors: G
authors: Champion
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Service de pédiatrie, centre hospitalier universitaire Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors: L
authors: L
authors: Kam
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: R
authors: R
authors: Ouédraogo
authors: Unité de formation et de recherche en sciences de la santé, Ouagadougou, Burkina Faso; Service de pédiatrie médicale, centre hospitalier universitaire pédiatrique Charles-de-Gaulle, Ouagadougou, Burkina Faso.
authors: D
authors: D
authors: Yé
mesh_terms: D058186:Acute Kidney Injury / Q000453:epidemiology / Q000209:etiology*; D001238:Asphyxia Neonatorum / Q000150:complications*; D002050:Burkina Faso; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007677:Kidney Function Tests; D008297:Male; D011446:Prospective Studies