title: Negotiating excess treatment costs in a clinical research trial: the good, the bad and the innovative.
abstract: Barriers to recovering the excess treatment costs associated with health research from local organisations in the United Kingdom can increase research costs, delay completion of high- quality studies and risk disenfranchising health trusts and patients from participation. The authors demonstrate how the process for recovering excess treatment costs at a local National Health Service (NHS) trust level in a multicentre study was inconsistent and resulted in excess effort and cost to the research budget. An innovative example of how an organisation acting as a broker between commissioners and researchers facilitated a more timely excess treatment cost agreement is highlighted.
  
  
  BACKGROUND
  Current Controlled Trials ISRCTN68798818, registered on 18 February 2014.
authors: School of Health and Related Research, University of Sheffield, 107 Innovation Centre, 217, Portobello, Sheffield, S1 4DP, UK. r.l.palmer@sheffield.ac.uk.
authors: Rebecca
authors: R
authors: Palmer
authors: School of Health and Related Research, University of Sheffield, 107 Innovation Centre, 217, Portobello, Sheffield, S1 4DP, UK. madeleine.harrison@sheffield.ac.uk.
authors: Madeleine
authors: M
authors: Harrison
authors: School of Health and Related Research, University of Sheffield, 107 Innovation Centre, 217, Portobello, Sheffield, S1 4DP, UK. e.a.cross@sheffield.ac.uk.
authors: Elizabeth
authors: E
authors: Cross
authors: School of Health and Related Research, University of Sheffield, 107 Innovation Centre, 217, Portobello, Sheffield, S1 4DP, UK. p.m.enderby@sheffield.ac.uk.
authors: Pam
authors: P
authors: Enderby
mesh_terms: D035843:Biomedical Research / Q000191:economics*; D002986:Clinical Trials as Topic / Q000191:economics*; D017048:Health Care Costs; D006801:Humans