title: Multiphoton Ionization Time-of-Flight Mass Spectrometry for the Detection of Bioactive Lignan.
abstract: Multiphoton ionization time-of-flight mass spectrometry (MPI-TOFMS) combined with a pulsed laser for sample vaporization was developed for the detection of a low-volatile compound in a solution. A solution containing Taiwanin A ((3E,4E)-3,4-bis(1,3-benzodioxol-5-ylmethylene)dihydro-2(3H)-furanone), which is a lignan that has an anticancer effect, was employed in the present study. Consequently, Taiwanin A could be detected by irradiating a laser pulse for vaporization to an inlet nozzle, rather than by heating. Therefore, the present method could be effective for detecting compounds with lower volatilities in a liquid sample.
authors: Department of Materials Science and Engineering, Graduate School of Engineering, University of Fukui.
authors: Tomohiro
authors: T
authors: Uchimura
authors: Goro
authors: G
authors: Tokumoto
authors: Onon
authors: O
authors: Batnyam
authors: Chih-Wei
authors: CW
authors: Chou
authors: Satoshi
authors: S
authors: Fujita
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry; D005663:Furans / Q000032:analysis* / Q000737:chemistry*; D006358:Hot Temperature; D007834:Lasers; D008024:Ligands; D017705:Lignans / Q000032:analysis* / Q000737:chemistry*; D017785:Photons; D012996:Solutions; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*; D014835:Volatilization
chemical_list: D000970:Antineoplastic Agents; D005663:Furans; D008024:Ligands; D017705:Lignans; D012996:Solutions; C419332:taiwanin A