title: Corneal elevation in a large number of myopic Chinese patients.
abstract: OBJECTIVE
  To establish a normative database for corneal elevation in Chinese myopic patients who underwent refractive surgery, and analyze the association of corneal elevation with sex, age, and ocular parameters.
  
  
  METHODS
  A total of 3000 eyes in 1500 patients were evaluated with the Pentacam. Anterior and posterior elevations were measured at the apex and thinnest point. Normative thresholds were defined according to the Tukey method. Univariate and multivariate analyses were performed to assess the association of corneal elevation with sex, age, and ocular parameters.
  
  
  RESULTS
  Normal upper limits for corneal elevation in adult Chinese were 4.95μm, 5.25μm, 6.2μm, and 11.0μm at the anterior apex, anterior thinnest point, posterior apex, and posterior thinnest point, respectively. Thinner corneal pachymetry at the apex and greater anterior corneal astigmatism tended to show greater anterior corneal elevation values. Younger age, greater anterior corneal astigmatism, lower anterior and posterior keratometry, and shallower anterior chamber depth resulted in greater posterior corneal elevation values.
  
  
  CONCLUSIONS
  Locally derived thresholds may offer higher sensitivity and specificity when screening eyes for myopic refractive surgery, and keratoconic and post-orthokeratology eyes. Anterior and posterior corneal elevation at the apex and thinnest point were associated significantly with anterior corneal astigmatism, showing a positive correlation.
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China; Department of Ophthalmology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.
authors: Jinglu
authors: J
authors: Ying
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
authors: Qinmei
authors: Q
authors: Wang
authors: Department of Ophthalmology, University of Arizona, Tucson, AV, United States.
authors: Michael W
authors: MW
authors: Belin
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
authors: Ting
authors: T
authors: Wan
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
authors: Shishi
authors: S
authors: Lin
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
authors: Yifan
authors: Y
authors: Feng
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China.
authors: Rongrong
authors: R
authors: Gao
authors: School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, China. Electronic address: vip999vip@163.com.
authors: Jinhai
authors: J
authors: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D001251:Astigmatism / Q000175:diagnosis* / Q000453:epidemiology* / Q000601:surgery; D002681:China / Q000453:epidemiology; D015897:Comorbidity; D063171:Corneal Pachymetry / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000175:diagnosis* / Q000453:epidemiology* / Q000601:surgery; D015995:Prevalence; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D055815:Young Adult
keywords: Corneal elevation; Myopia; Normative database; Scheimpflug imaging