title: [Area specific differences in lung function indices and prevalence of airflow obstruction in adults: findings from people in 10 areas in China].
abstract: OBJECTIVE
  To describe the area specific differences in lung function indices and prevalence of airflow obstruction (AFO) in adults found by China Kadoorie Biobank (CKB) study, involving 512 495 adults, in 10 areas in China.
  
  
  METHODS
  The detailed information on lung function indices (FEV, and FVC) and prevalence of AFO (diagnosed according to GOLD and LLN criteria) of subjects aged 30-79 years were analyzed, those with abnormal lung function indices at baseline survey were excluded.
  
  
  RESULTS
  The FEV1 and FVC among males (2.66 L, 3.16 L) were higher than those among females (1.99 L, 2.35 L). The FEV1 and FVC were highest in Henan and Harbin. The prevalence of AFO diaonosed according to GOLD criteria was 5.13% in males, higher than that in females (3.75%). The prevalence of AFO was higher in rural area than in urban area (males: 6.32% vs. 3.47%; females: 4.26% vs. 2.97%). The prevalence of AFO was highest in Sichuan (13.34% in males, 10.70% in females), followed by that in Suzhou, Henan and Hunan. The prevalence of AFO diagnosed according to LLN criteria (6.93% in males, 6.29% in females) was higher than that diagnosed according to GOLD criteria, but the area specific difference was similar.
  
  
  CONCLUSIONS
  The lung function indices and the prevalence of AFO in adults varied greatly among the 10 areas covered by CKB study.
authors: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors: Fengling
authors: F
authors: Lan
authors: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors: Jun
authors: J
authors: Lyu
authors: Chinese Academy of Medical Sciences.
authors: Yu
authors: Y
authors: Guo
authors: Chinese Academy of Medical Sciences.
authors: Zheng
authors: Z
authors: Bian
authors: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors: Canqing
authors: C
authors: Yu
authors: Chinese Academy of Medical Sciences.
authors: Huiyan
authors: H
authors: Zhou
authors: Chinese Academy of Medical Sciences.
authors: Yunlong
authors: Y
authors: Tan
authors: Chinese Academy of Medical Sciences.
authors: Pei
authors: P
authors: Pei
authors: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China; Email: caoweihua60@163.com.
authors: Weihua
authors: W
authors: Cao
authors: National Center for Food Safety Risk Assessment of China.
authors: Junshi
authors: J
authors: Chen
authors: Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU), Nuffield Department of Population Health, University of Oxford, UK.
authors: Zhengming
authors: Z
authors: Chen
authors: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China; Chinese Academy of Medical Sciences.
authors: Liming
authors: L
authors: Li
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008173:Lung Diseases, Obstructive / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012129:Respiratory Function Tests; D011795:Surveys and Questionnaires