title: Visual Assay of Total Iron in Human Serum with Bathophenanthrolin Disulfonate-accommodated MCM-41.
abstract: A simple visual method for determining the total iron in human serum is proposed based on color development in the nanospace of mesoporous silica MCM-41 and a chromogenic ligand bathophenathroline disulfonate (BPS). Observing the color intensity of a complex between iron(II) and BPS devloped on the MCM-41 material by the naked eye enabled us to quntify iron(II) with a detection limit of 0.5 μM. The BPS-loaded MCM-41 was successfully applied for quantifying the total iron in human serum.
authors: Department of Chemistry, College of Humanities and Sciences, Nihon University.
authors: Misato
authors: M
authors: Sakamoto
authors: Keita
authors: K
authors: Hizawa
authors: Manabu
authors: M
authors: Hosaka
authors: Masao
authors: M
authors: Sugawara
mesh_terms: D000327:Adsorption; D000328:Adult; D002138:Calibration; D003116:Color; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007501:Iron / Q000097:blood*; D057230:Limit of Detection; D008055:Lipids / Q000737:chemistry; D008297:Male; D010618:Phenanthrolines / Q000737:chemistry*; D011437:Propylamines / Q000737:chemistry; D012709:Serum Albumin / Q000737:chemistry; D012821:Silanes / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry*
chemical_list: D008055:Lipids; C509968:MCM-41; D010618:Phenanthrolines; D011437:Propylamines; D012709:Serum Albumin; D012821:Silanes; C088294:3-aminopropyltrimethoxysilane; C017049:bathophenanthroline disulfonic acid; D012822:Silicon Dioxide; D007501:Iron