title: Cutaneous Melanoma, Hodgkin's Lymphoma and non-Hodgkin's Lymphoma: Common Risk Factors?
abstract: An epidemiological cross-sectional study was conducted to evaluate the association between cutaneous melanoma, Hodgkin's lymphoma and non-Hodgkin's lymphoma in 40 European countries.
  
  
  
  Incidence rates were obtained from the database of the International Agency for Research of Cancer (IARC). We analyzed age-adjusted and gender-stratified incidence rates for cutaneous melanoma, Hodgkin's lymphoma and non-Hodgkin's lymphoma in 40 European countries. All European countries included had registration systems that fulfilled the quality criteria of IARC. Normal distribution of the variables was examined using Kolmorov-Smirnov test before calculating their correlations using Pearson's Correlation test.
  
  
  
  In males, positive correlations were found between cutaneous melanoma, Hodgkin's lymphoma (r=0.14, p=0.38), and non-Hodgkin's lymphoma (r=0.64, p<0.001). In females, negative correlation was found between cutaneous melanoma and Hodgkin's lymphoma (r=0.28, p=0.08), however, positive correlation was found between cutaneous melanoma and non-Hodgkin's lymphoma (r=0.72, p<0.001).
  
  
  
  Our findings raise the hypothesis about common risk factors for cutaneous melanoma and non-Hodgkin's lymphoma. New epidemiological and genetic studies are needed to identify possible common risk factors.
authors: Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Cordoba, Spain.|Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors: Mohamed Farouk
authors: MF
authors: Allam
authors: Dermatology Department, Alto Guadalquivir Hospital, Andújar (Jaén), Spain.
authors: Pablo Fernández-Crehuet
authors: PF
authors: Serrano
authors: Dermatology Department, Alto Guadalquivir Hospital, Andújar (Jaén), Spain.
authors: José Luis Fernández-Crehuet
authors: JL
authors: Serrano
authors: Department of Community, Environmental and Occupational Medicine, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
authors: Khaled Mahmoud
authors: KM
authors: Abd Elaziz
authors: Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Cordoba, Spain.
authors: Amparo Serrano
authors: AS
authors: Del Castillo
authors: Department of Preventive Medicine and Public Health, Faculty of Medicine, University of Cordoba, Cordoba, Spain.
authors: Rafael Fernández-Crehuet
authors: RF
authors: Navajas
mesh_terms: D003430:Cross-Sectional Studies; D005060:Europe / Q000453:epidemiology; D005260:Female; D006689:Hodgkin Disease / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D015994:Incidence; D008228:Lymphoma, Non-Hodgkin / Q000453:epidemiology* / Q000209:etiology*; D008297:Male; D008545:Melanoma / Q000453:epidemiology* / Q000209:etiology*; D012307:Risk Factors; D012878:Skin Neoplasms; D000096142:Cutaneous Malignant Melanoma
keywords: Hodgkin's lymphoma; ecological; epidemiology; melanoma; non-Hodgkin's lymphoma