title: Complete genome sequence of Streptomyces reticuli, an efficient degrader of crystalline cellulose.
abstract: We report the complete, GC-rich genome sequence of the melanin producer Streptomyces reticuli Tü 45 (S. reticuli) that targets and degrades highly crystalline cellulose by the concerted action of a range of biochemically characterized proteins. It consists of a linear 8.3 Mb chromosome, a linear 0.8 Mb megaplasmid, a linear 94 kb plasmid and a circular 76 kb plasmid. Noteworthy, the megaplasmid is the second largest known Streptomyces plasmid. Preliminary analysis reveals, among others, 43 predicted gene clusters for the synthesis of secondary metabolites and 456 predicted genes for binding and degradation of cellulose, other polysaccharides and carbohydrate-containing compounds.
authors: Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
authors: Daniel
authors: D
authors: Wibberg
authors: Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
authors: Arwa
authors: A
authors: Al-Dilaimi
authors: Center for Biotechnology, Bielefeld University, Bielefeld, Germany.
authors: Tobias
authors: T
authors: Busche
authors: Applied Genetics of Microorganisms, Department of Biology and Chemistry, University of Osnabrueck, Osnabrueck, Germany.
authors: Ina
authors: I
authors: Wedderhoff
authors: Applied Genetics of Microorganisms, Department of Biology and Chemistry, University of Osnabrueck, Osnabrueck, Germany.
authors: Hildgund
authors: H
authors: Schrempf
authors: Center for Biotechnology, Bielefeld University, Bielefeld, Germany. Electronic address: joern@cebitec.uni-bielefeld.de.
authors: Jörn
authors: J
authors: Kalinowski
authors: Applied Genetics of Microorganisms, Department of Biology and Chemistry, University of Osnabrueck, Osnabrueck, Germany. Electronic address: ortiz@biologie.uni-osnabrueck.de.
authors: Darío
authors: D
authors: Ortiz de Orué Lucana
mesh_terms: D002482:Cellulose / Q000378:metabolism; D016680:Genome, Bacterial / Q000235:genetics*; D013302:Streptomyces / Q000235:genetics*
chemical_list: D002482:Cellulose
keywords: Cellulases; Polysaccharide-binding proteins; Secondary metabolites; Streptomycetes