title: Multimodality Imaging Strategies for the Assessment of Aortic Stenosis: Viewpoint of the Heart Valve Clinic International Database (HAVEC) Group.
abstract: Aortic stenosis is the most frequent valvular heart disease. In aortic stenosis, therapeutic decision essentially depends on symptomatic status, stenosis severity, and status of left ventricular systolic function. Surgical aortic valve replacement or transcatheter aortic valve implantation is the sole effective therapy in symptomatic patients with severe aortic stenosis, whereas the management of asymptomatic patients remains controversial and is mainly based on individual risk stratification. Imaging is fundamental for the initial diagnostic work-up, follow-up, and selection of the optimal timing and type of intervention. The present review provides specific recommendations for utilization of multimodality imaging to optimize risk stratification and therapeutic decision-making processes in aortic stenosis.
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Raluca
authors: R
authors: Dulgheru
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Philippe
authors: P
authors: Pibarot
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Partho P
authors: PP
authors: Sengupta
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Luc A
authors: LA
authors: Piérard
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Raphael
authors: R
authors: Rosenhek
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Julien
authors: J
authors: Magne
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Erwan
authors: E
authors: Donal
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Anne
authors: A
authors: Bernard
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Khalil
authors: K
authors: Fattouch
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Bernard
authors: B
authors: Cosyns
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Mani
authors: M
authors: Vannan
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.).
authors: Linda
authors: L
authors: Gillam
authors: From the University of Liège Hospital, GIGA Cardiovascular Sciences, Departments of Cardiology, Heart Valve Clinic, CHU Sart Tilman, Liège, Belgium (R.D., L.A.P., P.L.); Quebec Heart and Lung Institute, Department of Medicine, Quebec City, Quebec, Canada (P.P.); Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, Cardiology Department, New York, NY (P.P.S.); Department of Cardiology, Medical University of Vienna, Vienna, Austria (R.R.); CHU Limoges, Hôpital Dupuytren, Pôle Coeur-Poumon-Rein, Cardiology Department, Limoges, France (J.M.); CIC-IT U 804, CHU Rennes, Université Rennes 1, Cardiology Department, CHU RENNES, Rennes, France (E.D.); CHU Tours, France et Université de Tours, Cardiology Department, Tours, France (A.B.); Gruppo Villa Maria Care and Research, Anthea Hospital, Cardiology Department, Italy (K.F., P.L.); Cardiology, Centrum voor Hart en Vaatziekten, UZ Brussel, Belgium (B.C.); Piedmont Heart Institute, Cardiology Department, Atlanta, GA (M.V.); and Department of Cardiovascular Medicine, Morristown Medical Center, Morristown, NJ (L.G.). plancellotti@chu.ulg.ac.be.
authors: Patrizio
authors: P
authors: Lancellotti
mesh_terms: D000465:Algorithms; D001024:Aortic Valve Stenosis / Q000145:classification / Q000175:diagnosis* / Q000628:therapy; D015415:Biomarkers; D006801:Humans; D064847:Multimodal Imaging; D017410:Practice Guidelines as Topic; D011379:Prognosis; D018570:Risk Assessment
chemical_list: D015415:Biomarkers
keywords: aortic valve stenosis; biomarkers; echocardiography, Doppler; guideline; prognosis; standards