title: Non-typeable Haemophilus influenzae purulent pericarditis in a child with cystic fibrosis.
abstract: Early airway colonization and infection with Haemophilus influenzae in children with cystic fibrosis (CF) is common. Although the pathogenicity of non-typeable H. influenzae (NTHi) in patients with CF is controversial, this organism can cause both upper and lower respiratory tract infections. Extra-pulmonary disease, however, is rare. Purulent pericarditis is a suppurative complication of bacterial infection of the pericardial space that can arise as a result of direct extension from an adjacent infection. We describe a case of purulent pericarditis due to NTHi in a young child with CF that developed as a complication of inadequately treated bronchopneumonia.
authors: Divisions of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Kevin J
authors: KJ
authors: Downes
authors: Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Kamal
authors: K
authors: Abulebda
authors: Division of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Christopher
authors: C
authors: Siracusa
authors: Division of Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Ryan
authors: R
authors: Moore
authors: Divisions of Infectious Diseases, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Mary A
authors: MA
authors: Staat
authors: Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.
authors: Sue E
authors: SE
authors: Poynter
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications* / Q000175:diagnosis; D006192:Haemophilus Infections / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D010493:Pericarditis / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D013902:Radiography, Thoracic
chemical_list: D000900:Anti-Bacterial Agents
keywords: cystic fibrosis; non-typeable Haemophilus influenzae; pericarditis