title: Mania following ketamine abuse.
abstract: Ketamine, a noncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor, has multiple clinical uses. On the other hand, ketamine abuse or recreational use has been gaining increasing attention. Induction of mania and psychotic symptoms has been reported in a patient receiving IV ketamine therapy for reflex sympathetic dystrophy. We here report a 26 year-old man who abused ketamine by inhalation for 12 months and developed manic-like symptoms after ketamine use. This case suggests a possible relationship between manic symptoms and ketamine abuse. To the best of our knowledge, this may be the first report regarding mania after recreational use of ketamine.
authors: Department of Psychiatry, China Medical University Hospital, Taichung, Taiwan.
authors: Yuan-Yuan
authors: YY
authors: Lu
authors: Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan; Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung, Taiwan.
authors: Chieh-Hsin
authors: CH
authors: Lin
authors: Department of Psychiatry, China Medical University Hospital, Taichung, Taiwan; Graduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan; Center for Drug Abuse and Addiction, China Medical University Hospital, Taichung, Taiwan.
authors: Hsien-Yuan
authors: HY
authors: Lane
keywords: antidepressant; bipolar; ketamine; mania