title: Organic base-catalysed solvent-tuned chemoselective carbotrifluoromethylation and oxytrifluoromethylation of unactivated alkenes.
abstract: An unprecedented and efficient organic base-catalysed highly chemoselective carbo- and oxytrifluoromethylation of unactivated alkenes with Togni's reagent was developed. The switchable chemoselectivity was tuned by simply changing the organic base catalyst and solvent. Mechanistic studies indicated that a radical cyclization pathway for carbotrifluoromethylation in DMSO and a carbocation pathway for oxytrifluoromethylation in DCE were probably involved.
authors: Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055, China. liuxy3@sustc.edu.cn.
authors: Ning-Yuan
authors: NY
authors: Yang
authors: Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055, China. liuxy3@sustc.edu.cn.
authors: Zhong-Liang
authors: ZL
authors: Li
authors: Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055, China. liuxy3@sustc.edu.cn.
authors: Liu
authors: L
authors: Ye
authors: Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055, China. liuxy3@sustc.edu.cn.
authors: Bin
authors: B
authors: Tan
authors: Department of Chemistry, South University of Science and Technology of China, Shenzhen, 518055, China. liuxy3@sustc.edu.cn.
authors: Xin-Yuan
authors: XY
authors: Liu