title: Non-alkaloid constituents of Vinca major.
abstract: The present study was designed to investigate the non-alkaloid compounds from the leaves and stems of Vinca major cultivated in Yunnan Province, China. The compounds were isolated using chromatographic techniques. The structures were elucidated by 1D- and 2D-NMR spectroscopic methods in combination with UV, IR, and MS analyses. The 1, 1-diphenyl-2-picrylhydrazyl (DPPH)-scavenging activity of Compounds 1-7 were evaluated. One new iridoid glycoside (compound 1), together with 11 known compounds, were isolated from Vinca major. Compounds 1, 5, and 6 showed moderate DPPH-scavenging activity, with IC50 values being 70.6, 32.8, and 62.2 μmol·L(-1), respectively. In conclusion, compound 1 is a newly identified iridoid glycoside with moderate antioxidant activity.
authors: Yunnan Institute of Food Safety, Kunming University of Science and Technology, Kunming, 650500, China; State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Gui-Guang
authors: GG
authors: Cheng
authors: Yunnan Institute of Food Safety, Kunming University of Science and Technology, Kunming, 650500, China.
authors: Hai-Yun
authors: HY
authors: Zhao
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Lu
authors: L
authors: Liu
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Yun-Li
authors: YL
authors: Zhao
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Chang-Wei
authors: CW
authors: Song
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Ji
authors: J
authors: Gu
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China.
authors: Wei-Bang
authors: WB
authors: Sun
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address: liuyaping@mail.kib.ac.cn.
authors: Ya-Ping
authors: YP
authors: Liu
authors: State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, China. Electronic address: xdluo@mail.kib.ac.cn.
authors: Xiao-Dong
authors: XD
authors: Luo
mesh_terms: D000975:Antioxidants / Q000494:pharmacology; D057889:Iridoid Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D018515:Plant Leaves / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D031053:Vinca / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D057889:Iridoid Glycosides
keywords: Antioxidant; Iridoid glycoside; Vinca major; Vinmaside A