title: Magnetically separable and recyclable Fe3O4-polydopamine hybrid hollow microsphere for highly efficient peroxidase mimetic catalysts.
abstract: Magnetic Fe3O4-polydopamine (PDA) hybrid hollow microspheres, in which Fe3O4 nanoparticles were firmly incorporated in the cross-linked PDA shell, have been prepared through the formation of core/shell PS/Fe3O4-PDA composites based on template-induced covalent assembly method, followed by core removal in a tetrahydrofuran solution. The morphology, composition, thermal property and magnetic property of the magnetic hybrid hollow microspheres were characterized by SEM, TEM, FT-IR, XRD, TGA, and vibrating sample magnetometer, respectively. Results revealed that the magnetic hybrid hollow microspheres had about 380 nm of inner diameter and about 30 nm of shell thickness, and 13.6 emu g(-1) of magnetization saturation. More importantly, the Fe3O4-PDA hybrid hollow microspheres exhibited intrinsic peroxidase-like activity, as they could quickly catalyze the oxidation of typical substrates 3,3',5,5'-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide. Compared with PDA/Fe3O4 composites where Fe3O4 nanoparticles were loaded on the surface of PDA microspheres, the stability of Fe3O4-PDA hybrid hollow microspheres was greatly improved. As-prepared magnetic hollow microspheres might open up a new application field in biodetection, biocatalysis, and environmental monitoring.
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China.
authors: Shujun
authors: S
authors: Liu
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China. Electronic address: jwfu@zzu.edu.cn.
authors: Jianwei
authors: J
authors: Fu
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China.
authors: Minghuan
authors: M
authors: Wang
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China.
authors: Ya
authors: Y
authors: Yan
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China.
authors: Qianqian
authors: Q
authors: Xin
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China.
authors: Lu
authors: L
authors: Cai
authors: School of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450052, PR China. Electronic address: qunxu@zzu.edu.cn.
authors: Qun
authors: Q
authors: Xu
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D002384:Catalysis; D007211:Indoles / Q000737:chemistry*; D060328:Magnetic Phenomena; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D008863:Microspheres; D015394:Molecular Structure; D010316:Particle Size; D010544:Peroxidases / Q000378:metabolism*; D011108:Polymers / Q000737:chemistry*; D016062:Porosity; D013499:Surface Properties
chemical_list: D007211:Indoles; D058185:Magnetite Nanoparticles; D011108:Polymers; C568283:polydopamine; D010544:Peroxidases
keywords: Catalyst; Fe(3)O(4); Hollow microspheres; Incorporated; Peroxidase-like; Polydopamine; Stability