title: Association Between Metabolic Control and Lipid Parameters in Indian Children with Type 1 Diabetes.
abstract: OBJECTIVE
  To compare lipid parameters between diabetics and controls and to study association between metabolic control and lipid profile.
  
  
  METHODS
  Lipid profile and HbA1c were measured (n=80, 39 boys) in diabetic children [age 10.7(3.4) y] and 54 controls, tests repeated after 1 year (in 45 diabetics).
  
  
  RESULTS
  Diabetic children had higher mean (SD) LDL-C [95.3(27.7) vs 84.5(26.4) mg/dL], lower HDL-C [48.2 (13.1) vs 53.1(11.9) mg/dl]. Moderate physical activity (P=0.014) protected against high LDL-C levels. HbA1c (P=0.00) predicted total and LDL-C levels. At 1year, 63% showed reduced LDL-C with improving HbA1c; 72% showed increased LDL-C with deteriorated HbA1c.
  
  
  CONCLUSIONS
  Improving metabolic control is cardinal to reduce cardiometabolic risk; physical activity is beneficial.
authors: Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, Pune, Maharashtra, India. Correspondence to: Dr Anuradha Khadilkar, Hirabai Cowasji Jehangir Medical Research Institute, Jehangir Hospital, 32 Sassoon Road, Pune.411 001, India. anuradhavkhadilkar@gmail.com.
authors: Lavanya
authors: L
authors: Parthasarathy
authors: Shashi
authors: S
authors: Chiplonkar
authors: Vaman
authors: V
authors: Khadilkar
authors: Anuradha
authors: A
authors: Khadilkar
mesh_terms: D000293:Adolescent; D002318:Cardiovascular Diseases / Q000150:complications / Q000453:epidemiology; D016022:Case-Control Studies; D002648:Child; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000150:complications / Q000453:epidemiology / Q000378:metabolism; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008055:Lipids / Q000097:blood*; D008297:Male; D009043:Motor Activity; D012307:Risk Factors
chemical_list: D008055:Lipids