title: Leptomeningeal metastasis in solid tumors with a special focus on lung cancer.
abstract: Leptomeningeal metastasis is a common problem in advanced solid tumor malignancies. A significant number of patients have underlying lung cancer. With the advent of better therapies, the management of leptomeningeal metastasis is gained more importance to improve survival and quality of live. This review article focuses on the epidemiology, clinical features, diagnostics and the recent management strategies directed towards leotomeningela metastasis from solid tumor, esp lung cancer.
authors: A
authors: A
authors: Joshi
authors: J
authors: J
authors: Ghosh
authors: Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: V
authors: V
authors: Noronha
authors: P M
authors: PM
authors: Parikh
authors: K
authors: K
authors: Prabhash
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000627:therapeutic use*; D000068258:Bevacizumab / Q000008:administration & dosage; D001943:Breast Neoplasms / Q000473:pathology*; D003561:Cytarabine / Q000008:administration & dosage; D066246:ErbB Receptors / Q000235:genetics; D006801:Humans; D007276:Injections, Intraventricular; D007278:Injections, Spinal / Q000009:adverse effects; D008175:Lung Neoplasms / Q000235:genetics / Q000473:pathology*; D008577:Meningeal Neoplasms / Q000175:diagnosis / Q000453:epidemiology / Q000235:genetics / Q000556:secondary* / Q000628:therapy*; D008727:Methotrexate / Q000008:administration & dosage; D011379:Prognosis; D000068878:Trastuzumab / Q000008:administration & dosage
chemical_list: D003561:Cytarabine; D000068258:Bevacizumab; D066246:ErbB Receptors; D000068878:Trastuzumab; D008727:Methotrexate