title: Changes in the markers of cardiac damage in men following long-distance and ultra-long-distance running races.
abstract: BACKGROUND
  The aim of this study was to compare pre- and postcompetition markers of cardiac damage in ultraendurance athletes.
  
  
  METHODS
  All the subjects had blood samples collected before starting and immediately after completing the running race, in order to analyze CK, hs-CRP, cTnI, and NT-proBNP.
  
  
  RESULTS
  Before starting the marathon, there were no differences between the groups for all of the tests. CK was significantly higher after the 308 km ultra-marathon than after the marathon and the 100 km ultra-marathon (P<0.001). In cTnI, the value after the 100 km ultra-marathon was significantly higher than that after the marathon and 308 km ultra-marathon, respectively (P<0.05, P<0.01). NT-proBNP was significantly higher after the 100 km and 308 km ultra-marathons than after the marathon (P<0.01, P<0.01). Hs-CRP was significantly higher after the 308 km ultra-marathon than after the marathon and the 100 km ultra-marathon (P<0.001).
  
  
  CONCLUSIONS
  cTnI was expressed after marathon and the 100 km ultra-marathon, and NT-proBNP exceeding the upper reference limit (URL) was expressed in long-distance races such as the 100 km and 308 km ultra-marathons. The highest expression of cTnI and NT-proBNP exceeding the URL was in the 100 km ultra-marathon, which may be caused by a combination of the moderate intensity of the exercise and the long-running distance.
authors: Department of Sport and Leisure Studies, Far East University, Chungbuk, Korea - kyj1383@yahoo.com.
authors: Jin H
authors: JH
authors: Yoon
authors: Yongbum
authors: Y
authors: Park
authors: Jaeki
authors: J
authors: Ahn
authors: Kyung A
authors: KA
authors: Shin
authors: Young J
authors: YJ
authors: Kim
mesh_terms: D000328:Adult; D056352:Athletes; D015415:Biomarkers / Q000097:blood; D006801:Humans; D008297:Male; D020097:Natriuretic Peptide, Brain / Q000097:blood*; D010446:Peptide Fragments / Q000097:blood*; D012420:Running; D019210:Troponin I / Q000097:blood*
chemical_list: D015415:Biomarkers; D010446:Peptide Fragments; D019210:Troponin I; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain