title: CRISPR-Cas Gatekeeper: Slow on the Uptake but Gets the Job Done.
abstract: Microbial CRISPR-Cas acts as a defense, but also as a gatekeeper controlling the flow of new genes into microbial genomes. In a recent Cell paper, Jiang et al. (2016) uncover the functional importance of transcription-dependent RNA targeting in type III-A CRISPR-Cas antiviral defense and provide insight into the co-evolution of virus-host symbioses.
authors: Department of Microbiology, University of Illinois at Urbana-Champaign. Electronic address: rwhitaker@life.illinois.edu.
authors: Rachel J
authors: RJ
authors: Whitaker
authors: Department of Microbiology, University of Illinois at Urbana-Champaign.
authors: Carin K
authors: CK
authors: Vanderpool
mesh_terms: D064113:CRISPR-Cas Systems; D020871:RNA Stability; D013204:Staphylococcus Phages / Q000235:genetics*; D013212:Staphylococcus epidermidis / Q000276:immunology*