title: Bilateral orbital myeloid sarcoma preceding acute myeloid leukemia in an adult: a case report and review of the literature.
abstract: BACKGROUND
  Acute myeloid leukemia is typically a disease of the older population and presents mostly in the fifth decade of life. Myeloid sarcoma is a rare initial presentation of acute myeloid leukemia. Previously it has only been documented in children and younger patients.
  
  
  METHODS
  We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old Caucasian man, with rearrangement of chromosome 11q23 involving the MLL gene.
  
  
  CONCLUSIONS
  We present an unusual case of retro-orbital myeloid sarcoma as an initial presentation of acute myeloid leukemia in a 43-year-old man, with rearrangement of chromosome 11q23 involving the MLL gene.
authors: Internal Medicine Department, Texas Tech University Health Sciences Center at the Permian Basin, 800 W. 4th Street, Odessa, TX, 79763, USA. Jesus.vera@ttuhsc.edu.
authors: Jesus
authors: J
authors: Vera-Aguilera
authors: Internal Medicine Department, Texas Tech University Health Sciences Center at the Permian Basin, 800 W. 4th Street, Odessa, TX, 79763, USA. Osama.mukarram@ttuhsc.edu.
authors: Osama
authors: O
authors: Mukarram
authors: Internal Medicine Department, Texas Tech University Health Sciences Center at the Permian Basin, 800 W. 4th Street, Odessa, TX, 79763, USA. prathibha.nutalapati@ttuhsc.edu.
authors: Prathibha
authors: P
authors: Nutalapati
authors: Internal Medicine Department, Texas Tech University Health Sciences Center at the Permian Basin, 800 W. 4th Street, Odessa, TX, 79763, USA. Mary.mok@ttuhsc.edu.
authors: Mary
authors: M
authors: Mok
authors: Internal Medicine Department, Texas Tech University Health Sciences Center at the Permian Basin, 800 W. 4th Street, Odessa, TX, 79763, USA. Anushi.bulumulle@ttuhsc.edu.
authors: Anushi
authors: A
authors: Bulumulle
authors: Departamento de Biología Celular y Tisular, Facultad de Medicina, Universidad Nacional Autónoma de México, México City, México. Anushi.bulumulle@ttuhsc.edu.
authors: Carlos
authors: C
authors: Vera-Aguilera
mesh_terms: D000328:Adult; D002880:Chromosomes, Human, Pair 11; D017809:Fatal Outcome; D015321:Gene Rearrangement; D011495:Histone-Lysine N-Methyltransferase / Q000235:genetics*; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000175:diagnosis* / Q000235:genetics; D008297:Male; D051788:Myeloid-Lymphoid Leukemia Protein / Q000235:genetics*; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000235:genetics; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000235:genetics
chemical_list: C497422:KMT2A protein, human; D051788:Myeloid-Lymphoid Leukemia Protein; D011495:Histone-Lysine N-Methyltransferase