title: Vibrational spectroscopy of metal carbonyls for bio-imaging and -sensing.
abstract: Transition metal carbonyls exhibit strong CO absorptions in the 2200-1800 cm(-1) region, which is free of interference from other functional groups. This feature has led to their applications in bio-imaging and -sensing, in particular through mid-IR, Raman and more recently, surface-enhanced Raman spectroscopy (SERS). Their use in mid-IR quantitative sensing based on vibrational intensities, and chemical sensing based on frequency shifts and vibrational lifetimes, is reviewed. Their development for Raman sensing following the breakthrough in SERS highlights the potential of coupling metal carbonyls to plasmonic nanostructures as novel optical materials for SERS-based bio-imaging and -sensing.
authors: Division of Chemistry and Biological Chemistry, Nanyang Technological University, Singapore. chmlwk@ntu.edu.sg and Bio-Optical Imaging Group, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore. malini_olivo@sbic.a-star.edu.sg.
authors: Zhiyong
authors: Z
authors: Lam
authors: Department of Chemistry, National Taiwan University, Taiwan.
authors: Kien Voon
authors: KV
authors: Kong
authors: Bio-Optical Imaging Group, Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A*STAR), Singapore. malini_olivo@sbic.a-star.edu.sg and School of Physics, National University of Ireland, Galway, Ireland.
authors: Malini
authors: M
authors: Olivo
authors: Division of Chemistry and Biological Chemistry, Nanyang Technological University, Singapore. chmlwk@ntu.edu.sg.
authors: Weng Kee
authors: WK
authors: Leong
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D009942:Organometallic Compounds / Q000737:chemistry*; D013055:Spectrophotometry, Infrared / Q000379:methods*; D013059:Spectrum Analysis, Raman / Q000379:methods*; D014732:Vibration
chemical_list: D009942:Organometallic Compounds