title: pH-Responsive Fe(III)-Gallic Acid Nanoparticles for In Vivo Photoacoustic-Imaging-Guided Photothermal Therapy.
abstract: pH-responsive biocompatible Fe(III)-gallic acid nanoparticles with strong near-infrared absorbance are very stable in mild acidic conditions, but easily decomposed in neutral conditions, which enables the nanoparticles to be stable in a tumor and easily metabolized in other organs, thus providing a safe nanoplatform for in vivo photoacoustic imaging/photothermal therapy theranostic applications.
authors: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, China.|Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, China.
authors: Jianfeng
authors: J
authors: Zeng
authors: The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
authors: Ming
authors: M
authors: Cheng
authors: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, China.|Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, China.
authors: Yong
authors: Y
authors: Wang
authors: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, China.|Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, China.
authors: Ling
authors: L
authors: Wen
authors: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, China.|Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, China.
authors: Ling
authors: L
authors: Chen
authors: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, China.|Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, China.|Institute for Superconducting & Electronic Materials, The University of Wollongong, NSW, 2500, Australia.
authors: Zhen
authors: Z
authors: Li
authors: The Second Affiliated Hospital of Soochow University, Suzhou, 215004, China.
authors: Yongyou
authors: Y
authors: Wu
authors: Institute of Chemistry, Chinese Academy of Sciences, Beijing National Laboratory for Molecular Sciences (BNLMS), Beijing, 100190, China.
authors: Mingyuan
authors: M
authors: Gao
authors: Center for Molecular Imaging and Nuclear Medicine, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Suzhou, 215123, China.|Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou, 215123, China.
authors: Zhifang
authors: Z
authors: Chai
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D002470:Cell Survival; D003952:Diagnostic Imaging; D005707:Gallic Acid / Q000737:chemistry*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D006979:Hyperthermia, Induced; D007501:Iron / Q000737:chemistry*; D008807:Mice, Inbred BALB C; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D061088:Photoacoustic Techniques / Q000379:methods*; D010789:Phototherapy; D014018:Tissue Distribution
chemical_list: D005707:Gallic Acid; D007501:Iron
keywords: metal complex nanoparticles; pH-sensitive nanoparticles; photoacoustic imaging; photothermal therapy