title: Simultaneous Quantification of Iodine and Other Elements in Infant Formula by ICP-MS Following an Acid Digestion with Nitric Acid and Hydrogen Peroxide.
abstract: A method for quantifying iodine in infant formula is described. Nitric acid and hydrogen peroxide converted iodine into iodate in microwave-assisted digestion and prevented iodine volatilization and memory effects. Acetic acid as a carbon source was added to both the sample and standard solutions as a countermeasure against carbon charge transfer to iodine and the addition of acetic acid helped to enhance the sensitivity. The instrument limit of quantification was 0.1 ng mL(-1) and the relative standard deviation was less than 3%. The spike recoveries were between 94.8 and 106%. Good agreement with the values obtained using the tetramethylammonium hydroxide method was obtained for infant formula sold in several countries. This method permitted the simultaneous determination of iodine and 12 other important elements (Na, Mg, P, K, Ca, Cr, Mn, Fe, Cu, Zn, Se and Mo) in infant formula.
authors: Analytical Research Center, Morinaga Milk Industry Co., Ltd.
authors: Koji
authors: K
authors: Fujisaki
authors: Hiroshi
authors: H
authors: Matsumoto
authors: Yukiko
authors: Y
authors: Shimokawa
authors: Kenji
authors: K
authors: Kiyotaki
mesh_terms: D019342:Acetic Acid / Q000032:analysis*; D002244:Carbon / Q000737:chemistry; D005504:Food Analysis; D006861:Hydrogen Peroxide / Q000737:chemistry*; D041943:Infant Formula / Q000737:chemistry*; D007455:Iodine / Q000737:chemistry*; D007477:Ions; D057230:Limit of Detection; D013058:Mass Spectrometry; D008872:Microwaves; D017942:Nitric Acid / Q000737:chemistry*; D000644:Quaternary Ammonium Compounds / Q000737:chemistry; D015203:Reproducibility of Results; D013691:Tellurium / Q000737:chemistry; D014131:Trace Elements / Q000032:analysis
chemical_list: D007477:Ions; D000644:Quaternary Ammonium Compounds; D014131:Trace Elements; D017942:Nitric Acid; D002244:Carbon; D007455:Iodine; D006861:Hydrogen Peroxide; C027917:tetramethylammonium; D013691:Tellurium; D019342:Acetic Acid