title: Genomic Information may Inhibit Weight-Related Behavior Change Inclinations Among Individuals in a Fear State.
abstract: As evidence mounts regarding associations between genetics and body weight, it is essential to understand how to communicate this information, and factors like emotion that could moderate the effectiveness of messages.
  
  
  
  We assessed influences of emotion on reactions to weight-related genomic information in a virtual clinical setting.
  
  
  
  An online representative US sample of overweight women was randomized to receive an emotion induction (anger, fear, or neutral) paired with information about genomic or behavioral influences on weight in an interaction with a virtual doctor.
  
  
  
  Receiving genomic information led to reduced attributions of lifestyle causes for weight and behavioral intentions, but only among individuals in a fear state.
  
  
  
  The current study is among the first to reinforce the concern that discussing genomic underpinnings of overweight could undercut health behavior, and highlights the importance of identifying factors like emotion that influence interpretation of genomic information. Clinicaltrials.gov NCT01888913.
authors: Social and Behavioral Research Branch, National Human Genome Research Institute, NIH, 31 Center Drive, B1B36, Bethesda, MD, 20892, USA. perskys@mail.nih.gov.
authors: Susan
authors: S
authors: Persky
authors: Basic Biobehavioral and Psychological Sciences Branch, Behavioral Research Program, National Cancer Institute, Rockville, MD, USA.
authors: Rebecca A
authors: RA
authors: Ferrer
authors: Behavioral Research Program, National Cancer Institute, Rockville, MD, USA.
authors: William M P
authors: WM
authors: Klein
mesh_terms: D001835:Body Weight; D004644:Emotions; D005260:Female; D023281:Genomics; D015438:Health Behavior; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008875:Middle Aged; D050177:Overweight / Q000523:psychology*
keywords: Genomics; Health-care communication; Obesity; Weight management