title: Self-reported symptoms of schizotypal and borderline personality disorder in patients with mood disorders.
abstract: BACKGROUND
  Distinguishing between symptoms of schizotypal (SPD) and borderline personality disorders (BPD) is often difficult due to their partial overlap and frequent co-occurrence. We investigated correlations in self-reported symptoms of SPD and BPD in questionnaires at the levels of both total scores and individual items, examining overlapping dimensions.
  
  
  METHODS
  Two questionnaires, the McLean Screening Instrument (MSI) for BPD and the Schizotypal Personality Questionnaire Brief (SPQ-B) for SPD, were filled in by patients with mood disorders (n=282) from specialized psychiatric care in a study of the Helsinki University Psychiatric Consortium. Correlation coefficients between total scores and individual items of the MSI and SPQ-B were estimated. Multivariate regression analysis (MRA) was conducted to examine the relationships between SPQ-B and MSI.
  
  
  RESULTS
  The Spearman's correlation between total scores of the MSI and SPQ-B was strong (rho=0.616, P<0.005). Items of MSI reflecting disrupted relatedness and affective dysregulation correlated moderately (rφ varied between 0.2 and 0.4, P<0.005) with items of SPQ. Items of MSI reflecting behavioural dysregulation correlated only weakly with items of SPQ. In MRA, depressive symptoms, sex and MSI were significant predictors of SPQ-B score, whereas symptoms of anxiety, age and SPQ-B were significant predictors of MSI score.
  
  
  CONCLUSIONS
  Items reflecting cognitive-perceptual distortions and affective symptoms of BPD appear to overlap with disorganized and cognitive-perceptual symptoms of SPD. Symptoms of depression may aggravate self-reported features of SPQ-B, and symptoms of anxiety features of MSI. Symptoms of behavioural dysregulation of BPD and interpersonal deficits of SPQ appear to be non-overlapping.
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: I
authors: I
authors: Baryshnikov
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland; Department of Social Services and Health Care, Helsinki, Finland.
authors: J
authors: J
authors: Suvisaari
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland; National Institute for Health and Welfare, Mental Health Unit, Mannerheimintie 166, 00271 Helsinki, Finland.
authors: K
authors: K
authors: Aaltonen
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: M
authors: M
authors: Koivisto
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: P
authors: P
authors: Näätänen
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: B
authors: B
authors: Karpov
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 590, 00029 Helsinki, Finland.
authors: T
authors: T
authors: Melartin
authors: Department of Social Services and Health Care, Helsinki, Finland.
authors: J
authors: J
authors: Oksanen
authors: City of Helsinki, Social Services and Healthcare, Helsinki, Finland; Aurora Hospital, P.O. Box 6800, 00099 Helsinki, Finland.
authors: K
authors: K
authors: Suominen
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: M
authors: M
authors: Heikkinen
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: T
authors: T
authors: Paunio
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland.
authors: G
authors: G
authors: Joffe
authors: Department of Psychiatry, University of Helsinki and Helsinki University Hospital, P.O. Box 22, (Välskärinkatu 12 A), 00014 Helsinki, Finland; National Institute for Health and Welfare, Mental Health Unit, Mannerheimintie 166, 00271 Helsinki, Finland. Electronic address: erkki.isometsa@hus.fi.
authors: E
authors: E
authors: Isometsä
mesh_terms: D000328:Adult; D001883:Borderline Personality Disorder / Q000175:diagnosis / Q000523:psychology; D003937:Diagnosis, Differential; D005260:Female; D005387:Finland / Q000453:epidemiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D019964:Mood Disorders / Q000453:epidemiology / Q000523:psychology; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics / Q000706:statistics & numerical data; D015203:Reproducibility of Results; D012569:Schizotypal Personality Disorder / Q000175:diagnosis / Q000523:psychology; D057566:Self Report; D012959:Socioeconomic Factors; D013223:Statistics as Topic; D011795:Surveys and Questionnaires; D014495:Universities
keywords: Borderline Personality Disorder; McLean Screening Instrument; Schizotypal Personality Disorder; Schizotypal Personality Questionnaire Brief