title: CENTRAL NERVOUS SYSTEM LIGNOCAINE TOXICITY IN AN INFANT FOLLOWING VENTRICULO-PERITONEAL SHUNT AND SPINA BIFIDA REPAIR: A CASE REPORT.
abstract: A 3.7 kg one-month-old male infant with Spina Bifida Cystica with Hydrocephalus had Ventriculo-Peritoneal (VP) Shunting and repair of the Spina Bifida Cystica done. Lignocaine with Adrenaline 1:100,000 was infiltrated intra-operatively to reduce blood loss. Overenthusiastic infiltration, an oversight, led to Lignocaine toxicity. In Pediatrics, prior calculation of maximum dosage, based on child's weight, and use of dilute solutions for multiple sites could have prevented this.
authors: N
authors: N
authors: Kituu
authors: W O G
authors: WO
authors: Mugenya
authors: P W
authors: PW
authors: Kituyi
mesh_terms: D000779:Anesthetics, Local / Q000008:administration & dosage / Q000009:adverse effects*; D000927:Anticonvulsants / Q000008:administration & dosage; D003975:Diazepam / Q000008:administration & dosage; D006801:Humans; D006849:Hydrocephalus / Q000601:surgery*; D007223:Infant; D007430:Intraoperative Care; D008012:Lidocaine / Q000008:administration & dosage / Q000009:adverse effects*; D008297:Male; D009207:Myoclonus / Q000139:chemically induced* / Q000628:therapy; D010102:Oxygen Inhalation Therapy / Q000379:methods; D016137:Spina Bifida Cystica / Q000601:surgery*; D016896:Treatment Outcome; D017287:Ventriculoperitoneal Shunt / Q000009:adverse effects
chemical_list: D000779:Anesthetics, Local; D000927:Anticonvulsants; D008012:Lidocaine; D003975:Diazepam