title: Technological developments for small-scale downstream processing of cell therapies.
abstract: Despite considerable regulatory and clinical hurdles, the development and use of cell-based therapies are gaining momentum. As more of these therapies move toward commercial approval and larger-scale distribution, associated manufacturing and processing technologies are being advanced. Modern technologies directed at downstream processing seek to distribute such therapies from the manufacturing site to the patient more efficiently and reliably. Novel small-scale downstream solutions boost the transformation of cell therapies from abstraction to reality.
authors: RepliCel, Life Sciences, Inc., Vancouver, British Columbia, Canada.
authors: R Lee
authors: RL
authors: Buckler
authors: BioCision, LLC, San Rafael, CA, USA.
authors: Eric J
authors: EJ
authors: Kunkel
authors: BioCision, LLC, San Rafael, CA, USA. Electronic address: maria@biocision.com.
authors: Maria L
authors: ML
authors: Thompson
authors: BioCision, LLC, San Rafael, CA, USA.
authors: Rolf O
authors: RO
authors: Ehrhardt
mesh_terms: D061249:Batch Cell Culture Techniques / Q000639:trends; D019149:Bioreactors; D064987:Cell- and Tissue-Based Therapy / Q000295:instrumentation / Q000379:methods* / Q000592:standards / Q000639:trends*; D015925:Cryopreservation / Q000379:methods; D003584:Cytological Techniques / Q000295:instrumentation / Q000379:methods; D006801:Humans; D055616:Microtechnology / Q000295:instrumentation / Q000379:methods* / Q000592:standards; D013048:Specimen Handling / Q000379:methods / Q000639:trends