title: Congenital Blaschkoid Angiolymphoid Hyperplasia With Eosinophilia of the Anogenital Region.
abstract: Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon, idiopathic vascular disorder. It manifests as dermal or subcutaneous red to brown papules or nodules, most commonly on the head and neck; other less common sites include the trunk, extremities, genitalia, lips, and oral mucosa. Although ALHE is a benign disease, lesions are often persistent and difficult to eradicate. ALHE occurs more frequently in Asian young and middle-aged women. Histologically, it is characterized by a florid vascular proliferation with hobnail epithelioid endothelial cells surrounding by lymphocytic and eosinophilic infiltrate. Here, we reported congenital ALHE in a 2-year-old girl. Unilateral lesions had a blaschkoid segmental distribution in the anogenital region and were successfully treated with the Nd:YAG laser.
authors: *Department of Dermatology, Tianjin Children's Hospital, Tianjin, China; †Department of Dermatology, Tianjin Medical University General Hospital, Tianjin, China; ‡Ackerman Academy of Dermatopathology, New York, NY; and §Department of Clinical Laboratory, Tianjin Medical University General Hospital, Tianjin, China.
authors: Hai-Hui
authors: HH
authors: Su
authors: Shi-Jun
authors: SJ
authors: Shan
authors: Dirk M
authors: DM
authors: Elston
authors: Ying
authors: Y
authors: Guo
authors: Jian-Long
authors: JL
authors: Men
mesh_terms: D001003:Anal Canal / Q000473:pathology; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000151:congenital* / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D005836:Genitalia, Female / Q000473:pathology; D006801:Humans; D053844:Lasers, Solid-State