title: Iridium(I) N-Heterocyclic Carbene (NHC)/Phosphine Catalysts for Mild and Chemoselective Hydrogenation Processes.
abstract: The directed chemoselective hydrogenation of olefins has been established by using iridium(I) catalysts, which feature a tuned NHC/phosphine ligand combination. This selective reduction process has been demonstrated in a wide array of solvents, including more environmentally acceptable media, also allowing further refinement of hydrogenation selectivity.
authors: Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, Scotland, G1 1XL, UK. w.kerr@strath.ac.uk.
authors: William J
authors: http://orcid.org/0000-0002-1332-785X
authors: WJ
authors: Kerr
authors: Department of Pure and Applied Chemistry, WestCHEM, University of Strathclyde, 295 Cathedral Street, Glasgow, Scotland, G1 1XL, UK.
authors: Richard J
authors: RJ
authors: Mudd
authors: GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage, England, SG1 2NY, UK.
authors: Jack A
authors: JA
authors: Brown
keywords: chemoselectivity; homogeneous catalysis; hydrogenation; iridium; reduction