title: Argonaute and Argonaute-Bound Small RNAs in Stem Cells.
abstract: Small RNAs are essential for a variety of cellular functions. Argonaute (AGO) proteins are associated with all of the different classes of small RNAs, and are indispensable in small RNA-mediated regulatory pathways. AGO proteins have been identified in various types of stem cells in diverse species from plants and animals. This review article highlights recent progress on how AGO proteins and AGO-bound small RNAs regulate the self-renewal and differentiation of distinct stem cell types, including pluripotent, germline, somatic, and cancer stem cells.
authors: Medical College, Hubei University of Arts and Science, Xiangyang 441053, Hubei, China. zhailihong@webmail.hzau.edu.cn.
authors: Lihong
authors: L
authors: Zhai
authors: Xiangyang Oral Hospital, Xiangyang 441003, Hubei, China. tobenumberone@yeah.net.
authors: Lin
authors: L
authors: Wang
authors: Medical College, Hubei University of Arts and Science, Xiangyang 441053, Hubei, China. tengfeng1217@webmail.hzau.cn.
authors: Feng
authors: F
authors: Teng
authors: Medical College, Hubei University of Arts and Science, Xiangyang 441053, Hubei, China. lanting_zhou@yeah.net.
authors: Lanting
authors: L
authors: Zhou
authors: Medical College, Hubei University of Arts and Science, Xiangyang 441053, Hubei, China. starking521@webmail.hzau.edu.cn.
authors: Wenjing
authors: W
authors: Zhang
authors: Medical College, Hubei University of Arts and Science, Xiangyang 441053, Hubei, China. xiaojuan@bjmu.edu.cn.
authors: Juan
authors: J
authors: Xiao
authors: Department of Neurosurgery, Medical School, the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Ying.Liu@uth.tmc.edu.|Center for Stem Cell and Regenerative Medicine, the Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases, University of Texas Health Science Center at Houston, Houston, TX 77030, USA. Ying.Liu@uth.tmc.edu.
authors: Ying
authors: Y
authors: Liu
authors: Department of Biochemistry and Molecular Medicine, School of Medicine, University of California, Davis, CA 95817, USA. wbdeng@ucdavis.edu.|Institute for Pediatric Regenerative Medicine, Shriners Hospitals for Children, Sacramento, CA 95817, USA. wbdeng@ucdavis.edu.
authors: Wenbin
authors: W
authors: Deng
mesh_terms: D000818:Animals; D060565:Argonaute Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D002352:Carrier Proteins / Q000378:metabolism; D005786:Gene Expression Regulation; D006801:Humans; D005810:Multigene Family; D011485:Protein Binding; D054730:Protein Interaction Domains and Motifs; D058727:RNA, Small Untranslated / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism*; D013234:Stem Cells / Q000378:metabolism*
chemical_list: D060565:Argonaute Proteins; D002352:Carrier Proteins; D058727:RNA, Small Untranslated
keywords: Argonaute; Piwi; small RNAs; stem cells