title: The Prognosis of IVF in Poor Responders Depending on the Bologna Criteria: A Large Sample Retrospective Study from China.
abstract: OBJECTIVE
  To analyze the treatment outcomes of patients who accepted IVF/ICSI-ET, diagnosed POR according to Bologna criteria.
  
  
  METHODS
  Retrospective cohort study of one reproductive medical center, from 1st Jan., 2009, to 31st Dec., 2014. All patients fulfilled the Bologna criteria and accept IVF/ICSI-ET treatment with stimulation cycle. The main outcome measures were clinical pregnancy rate (CPR) and live birth rate (LBR).
  
  
  RESULTS
  There were 5770 eligible cycles included in this study. The incidence of POR was 10.3% (6286/62194). The overall CPR was 18.7%, IR was 11.6%, LBR/ET was 11.5%, and LBR/OPU was 8.3%. The cycle cancellation for no available oocyte or embryo was 4.9% and 18.6%, respectively. The subgroup of younger POR patients got highest CPR and LBR/ET, which decreased while increasing maternal age. Within three attempts, the patients got similar CPR and LBR.
  
  
  CONCLUSIONS
  In conclusion, our study supports the Bologna criteria that defined women with poor IVF outcomes. But those younger than 42 years old with the first 3 attempts of IVF could got acceptable CPR and LBR.
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Shuo
authors: S
authors: Yang
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Xinna
authors: X
authors: Chen
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Xiumei
authors: X
authors: Zhen
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Haiyan
authors: H
authors: Wang
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Caihong
authors: C
authors: Ma
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Rong
authors: R
authors: Li
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Ping
authors: P
authors: Liu
authors: Peking University Third Hospital, No. 49, North Huayuan Road, Haidian District, Beijing 100191, China.
authors: Jie
authors: J
authors: Qiao
mesh_terms: D000328:Adult; D000367:Age Factors; D001723:Birth Rate; D002681:China; D004624:Embryo Transfer; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D011247:Pregnancy; D012189:Retrospective Studies