title: Ag-Incorporated FHA Coating on Pure Mg: Degradation and in Vitro Antibacterial Properties.
abstract: Fluoridated hydroxyapatite (FHA) coating can help retard the degradation of magnesium, and possess good biocompatibility. However, the antibacterial property of FHA is very limited. In this work, we aimed to incorporate silver into FHA structure to fabricate biocompatible and antibacterial coatings with enhanced anticorrosion property. The results showed that the Ag-FHA coating prepared by electrochemical deposition and subsequent immersion in AgNO3 solution was superior to the Ag-FHA coating prepared by coelectrodeposition in terms of crystal structure, surface morphology and corrosion resistance. The release of Ag(+) ion causing high antiplanktonic bacterial rate and excellent antiadherence property to MRSA. Meanwhile, good cell compatibility of MC3T3-E1 including cell viability, cell adhesion, and cell morphology was achieved under the controlled degradation. The balance of degradation and antimicrobial property of Ag-incorporated FHA coating made it an alternative in the application of surface modification for biodegradable Mg.
authors: State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University , Shanghai 200240, China.
authors: Changli
authors: C
authors: Zhao
authors: The Sixth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai 200233, China.
authors: Peng
authors: P
authors: Hou
authors: State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University , Shanghai 200240, China.
authors: Jiahua
authors: J
authors: Ni
authors: The Sixth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai 200233, China.
authors: Pei
authors: P
authors: Han
authors: The Sixth People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine , Shanghai 200233, China.
authors: Yimin
authors: Y
authors: Chai
authors: State Key Laboratory of Metal Matrix Composites, School of Materials Science and Engineering, Shanghai Jiao Tong University , Shanghai 200240, China.
authors: Xiaonong
authors: X
authors: Zhang
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D001419:Bacteria / Q000187:drug effects; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology; D002448:Cell Adhesion / Q000187:drug effects; D020099:Coated Materials, Biocompatible / Q000494:pharmacology; D003343:Corrosion; D006882:Hydroxyapatites / Q000737:chemistry* / Q000494:pharmacology; D008274:Magnesium / Q000378:metabolism; D012834:Silver / Q000737:chemistry; D013499:Surface Properties
chemical_list: D000900:Anti-Bacterial Agents; D001672:Biocompatible Materials; D020099:Coated Materials, Biocompatible; D006882:Hydroxyapatites; D012834:Silver; C028869:fluor-hydroxylapatite; D008274:Magnesium
keywords: FHA coating; antibacterial properties; degradation; magnesium; silver