title: Assessment of Growth of Infants Fed an Amino Acid-Based Formula.
abstract: OBJECTIVE
  This study's primary aim was to compare the growth (daily weight gain) of infants consuming a new (Test) amino acid-based formula (AAF) or a commercially available AAF (Control).
  
  
  METHODS
  Healthy infants were randomized to Test or Control from 14 to 112 days of age. Anthropometric measurements were taken at 14, 28, 56, 84, and 112 days of age. Tolerance records were completed prior to each visit. Serum albumin and plasma amino acids were ascertained in a subset of infants at 84 days of age.
  
  
  RESULTS
  A total of 119 subjects completed the study per protocol. Mean daily weight gains were 27.26 ± 4.92 g/day for Control and 27.42 ± 6.37 g/day for Test (P = 0.8812). There were no significant differences between groups in formula intake, adverse events, flatulence, spit-up/vomiting, mood, or sleep. Albumin and plasma amino acids were within normal limits for both groups.
  
  
  CONCLUSIONS
  Infants fed the new AAF had similar daily weight gains as infants fed a commercially available AAF.
authors: Division Chief, Division of Pediatric Gastroenterology, Department of Pediatrics, Le Bonheur Children's Hospital, Memphis, TN, USA.; Professor, Department of Pediatrics, The University of Tennessee Health Science Center, Memphis, TN, USA.
authors: Mark
authors: M
authors: Corkins
authors: Nestlé Nutrition, Florham Park, NJ, USA.
authors: Laura A
authors: LA
authors: Czerkies
authors: Nestlé Nutrition, Florham Park, NJ, USA.
authors: Heidi M
authors: HM
authors: Storm
authors: Professor and Department Chair, Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA.
authors: Shumei
authors: S
authors: Sun
authors: Nestlé Nutrition, Vevey, Switzerland.
authors: José M
authors: JM
authors: Saavedra
keywords: amino acid-based formula; growth; infant formula