title: [Epigenetics in transgenerational responses to environmental impacts: from facts and gaps].
abstract: The existence of non-genetic and non-cultural mechanisms that transfer information on the memory of parental exposures to various environments, determining the reactivity of the following generations to their environments during their life, are of growing interest. Yet fundamental questions remain about the nature, the roles and relative importance of epigenetic marks and processes, non-coding RNAs, or other mechanisms, and their persistence over generations. A model incorporating the various transmission systems, their cross-talks and windows of susceptibility to the environment as a function of sex/gender of parent and offspring, has yet to be built.
authors: Inra, UMR1198, biologie du développement et reproduction, Domaine de Vilvert, Bâtiment 230, F-78350 Jouy-en-Josas, France.
authors: Claudine
authors: C
authors: Junien
authors: Inra, UMR1198, biologie du développement et reproduction, Domaine de Vilvert, Bâtiment 230, F-78350 Jouy-en-Josas, France.
authors: Polina
authors: P
authors: Panchenko
authors: Inra, UMR1198, biologie du développement et reproduction, Domaine de Vilvert, Bâtiment 230, F-78350 Jouy-en-Josas, France.
authors: Sara
authors: S
authors: Fneich
authors: Institut Carmen, Inserm U1060, Oullins, France.
authors: Luciano
authors: L
authors: Pirola
authors: Institut Carmen, Inserm U1060, Oullins, France.
authors: Sabrina
authors: S
authors: Chriett
authors: Inra, UMR 1280, université de Nantes, Institut des maladies de l'appareil digestif, F-44000 Nantes, France.
authors: Valérie
authors: V
authors: Amarger
authors: Inra, UMR 1280, université de Nantes, Institut des maladies de l'appareil digestif, F-44000 Nantes, France.
authors: Bertrand
authors: B
authors: Kaeffer
authors: Inra, UMR 1280, université de Nantes, Institut des maladies de l'appareil digestif, F-44000 Nantes, France.
authors: Patricia
authors: P
authors: Parnet
authors: Inserm UMR1037, Centre de recherches en cancérologie de Toulouse, Université de Toulouse III Paul Sabatier, F-31037 Toulouse, France.
authors: Jérome
authors: J
authors: Torrisani
authors: Inra, UMR 1280, université de Nantes, Institut des maladies de l'appareil digestif, F-44000 Nantes, France.
authors: Francisco
authors: F
authors: Bolaños Jimenez
authors: Inra, UMR1198, biologie du développement et reproduction, Domaine de Vilvert, Bâtiment 230, F-78350 Jouy-en-Josas, France.
authors: Hélène
authors: H
authors: Jammes
authors: Inra, UMR1198, biologie du développement et reproduction, Domaine de Vilvert, Bâtiment 230, F-78350 Jouy-en-Josas, France.
authors: Anne
authors: A
authors: Gabory
mesh_terms: D019175:DNA Methylation / Q000502:physiology; D004198:Disease Susceptibility / Q000209:etiology; D004777:Environment; D044127:Epigenesis, Genetic / Q000502:physiology*; D005191:Family Characteristics; D005260:Female; D059647:Gene-Environment Interaction; D006801:Humans; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000209:etiology* / Q000235:genetics; D022661:RNA, Untranslated / Q000502:physiology
chemical_list: D022661:RNA, Untranslated