title: Radionuclide Imaging Applications in Cardiomyopathies and Heart Failure.
abstract: Multiple epidemiological factors including population aging and improved survival after acute coronary syndromes have contributed to a heart failure (HF) prevalence in the USA in epidemic proportions. In the absence of transplantation, HF remains a progressive disease with poor prognosis. The structural and functional abnormalities of the myocardium in HF can be assessed by various radionuclide imaging techniques. Radionuclide imaging may be uniquely suited to address several important clinical questions in HF such as identifying etiology and guiding the selection of patients for coronary revascularization. Newer approaches such as autonomic innervation imaging, phase analysis for synchrony assessment, and other molecular imaging techniques continue to expand the applications of radionuclide imaging in HF. In this manuscript, we review established and evolving applications of radionuclide imaging for the diagnosis, risk stratification, and management of HF.
authors: Heart and Vascular Institute, University of Pittsburgh Medical Center, A-429 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA, 15213, USA.
authors: Matthew E
authors: ME
authors: Harinstein
authors: Heart and Vascular Institute, University of Pittsburgh Medical Center, A-429 Scaife Hall, 200 Lothrop Street, Pittsburgh, PA, 15213, USA. somanp@upmc.edu.
authors: Prem
authors: P
authors: Soman
mesh_terms: D009202:Cardiomyopathies / Q000000981:diagnostic imaging* / Q000628:therapy; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D016027:Heart Transplantation; D006353:Heart-Assist Devices; D006801:Humans; D055414:Myocardial Perfusion Imaging / Q000379:methods; D009204:Myocardial Revascularization / Q000379:methods; D018579:Patient Selection; D018570:Risk Assessment / Q000379:methods
keywords: Cardiomyopathy; Ejection fraction; Heart failure; Myocardial perfusion imaging; Nuclear cardiology; Radionuclide imaging