title: A Rare Nasopharyngeal Teratoma Arising From the Vomer.
abstract: Teratomas are rare germ cell neoplasms derived from the 3 germinal layers (ectoderm, mesoderm, and endoderm). Nasopharyngeal teratoma is a very rare teratoma arising anywhere from the oronasal cavity, regarded as an expanding, avity filling lesion, with a high mortality rate because of severe airway obstruction, especially in the neonatal period and make up only 2% of all teratomas. The authors present a case of an infant girl with a single, finger-like, hairy teratoma arising from the vomer and protruding from the mouth with bilateral complete cleft palate, cleft lip, and cleft alveolus. Complete intraoral resection of the teratoma and cleft lip repair was conducted simultaneously. Reconstruction of the cleft palate was performed at a later stage. Recurrence occurred 9 months after surgery and extended complete surgical excision was performed after recurrence, with no recurrence observed again to date. Histopathologic examination confirmed the diagnosis of congenital mature teratoma.
authors: *Department of Cleft Lip and Palate Surgery, West China College of Stomatology, Sichuan University, Chengdu, China †Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH.
authors: Xiaoxiao
authors: X
authors: Pang
authors: Hyuk-Jae
authors: HJ
authors: Kwon
authors: Bing
authors: B
authors: Shi
authors: Chenghao
authors: C
authors: Li
mesh_terms: D000539:Alveolar Process / Q000002:abnormalities; D002971:Cleft Lip / Q000175:diagnosis; D002972:Cleft Palate / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007223:Infant; D009303:Nasopharyngeal Neoplasms / Q000151:congenital*; D009364:Neoplasm Recurrence, Local / Q000473:pathology; D013724:Teratoma / Q000151:congenital*; D055172:Vomer / Q000473:pathology*