title: Building the Frequency Profile of the Core Promoter Element Patterns in the Three ChromHMM Promoter States at 200bp Intervals: A Statistical Perspective.
abstract: Recently, the Encyclopedia of DNA Elements (ENCODE) Analysis Working Group converted data from ChIP-seq analyses from the Broad Histone track into 15 corresponding chromatic maps that label sequences with different kinds of histone modifications in promoter regions. Here, we publish a frequency profile of the three ChromHMM promoter states, at 200-bp intervals, with particular reference to the existence of sequence patterns of promoter elements, GC-richness, and transcription starting sites. Through detailed and diligent analysis of promoter regions, researchers will be able to uncover new and significant information about transcription initiation and gene function.
authors: Bioinformatics Laboratory, School of Engineering, Ewha Womans University, Seoul 03760, Korea.; Human Language Technology Program, Department of Linguistics, University of Arizona, Tucson, AZ 85721, USA.
authors: Heather
authors: H
authors: Lent
authors: Bioinformatics Laboratory, School of Engineering, Ewha Womans University, Seoul 03760, Korea.
authors: Kyung-Eun
authors: KE
authors: Lee
authors: Bioinformatics Laboratory, School of Engineering, Ewha Womans University, Seoul 03760, Korea.
authors: Hyun-Seok
authors: HS
authors: Park
keywords: chromatin state; epigenetics; epigenomics; genetic promoter regions