title: Canine and feline retinal lymphoma: a retrospective review of 12 cases.
abstract: This retrospective study identified 12 cases (6 canine and 6 feline) of ocular lymphoma with extensive retinal involvement and relative sparing of other ocular tissues. Our objectives were to describe the morphologic and immunohistochemical features of retinal lymphoma, assess the degree of correlation to the human counterpart, assign subtypes based on the veterinary-adapted WHO classification system, and promote accurate reporting of retinal involvement in cases of intraocular lymphoma. Our findings suggest that a distinct retinal tropism is quite rare, representing approximately 1% of all cases of canine and feline ocular lymphoma. No breed or sex predispositions were identified. The mean age of the affected animal was 7 years (range 4-10) and 11 years (range 6-19) for dogs and cats, respectively. Nine cases (5 canine and 4 feline) were classified as diffuse large B-cell lymphoma (DLBCL) subtype. The remaining cases were classified as peripheral T-cell lymphoma (PTCL).
authors: Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors: Jennifer L
authors: JL
authors: Malmberg
authors: Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors: Teresa
authors: T
authors: Garcia
authors: Department of Pathobiological Sciences, University of Wisconsin School of Veterinary Medicine, Madison, WI, USA.
authors: Richard R
authors: RR
authors: Dubielzig
authors: Department of Microbiology, Immunology, and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
authors: E J
authors: EJ
authors: Ehrhart
mesh_terms: D000818:Animals; D002371:Cat Diseases / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D002415:Cats; D004283:Dog Diseases / Q000145:classification / Q000175:diagnosis / Q000473:pathology*; D004285:Dogs; D005260:Female; D008223:Lymphoma / Q000145:classification / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D016411:Lymphoma, T-Cell, Peripheral / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary; D008297:Male; D019572:Retinal Neoplasms / Q000145:classification / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D012189:Retrospective Studies
keywords: canine; feline; ocular neoplasia; retinal lymphoma