title: Comparison of Fecal Microbiota between German Holstein Dairy Cows with and without Left-Sided Displacement of the Abomasum.
abstract: One of the most common diseases in high-performance German Holstein dairy cows is left-sided displacement of the abomasum (LDA). Hypomotility of the abomasum is detrimental during the pathogenesis of LDA. It is known that improper interactions between the gut microbiota and the enteric nervous system contribute to dysfunctions of gastrointestinal motility. Therefore, we hypothesized that the gut microbial composition will be different between German Holstein dairy cows with and without LDA. We used 16S rRNA gene analysis to evaluate whether there are any differences in bacterial composition between German Holstein dairy cows with and without LDA. Even though our data are limited to being used to correlate compositional changes with corresponding functional aspects in the pathogenesis of LDA, results from this study show that the fecal microbial compositions of German Holstein dairy cows with LDA shifted and were less diverse than those in normal cows. In particular,Spirochaeteswere absent in cows with LDA.
authors: College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
authors: Eun-Sik
authors: ES
authors: Song
authors: College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
authors: Sang Il
authors: SI
authors: Jung
authors: College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
authors: Hyung-Jin
authors: HJ
authors: Park
authors: College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
authors: Kyoung-Won
authors: KW
authors: Seo
authors: College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea.
authors: Jeong-Hoon
authors: JH
authors: Son
authors: Department of Animal Resource and Science, Dankook University, Cheonan, South Korea.
authors: Sanghyun
authors: S
authors: Hong
authors: Department of Animal Resource and Science, Dankook University, Cheonan, South Korea.
authors: Minkyung
authors: M
authors: Shim
authors: Department of Animal Resource and Science, Dankook University, Cheonan, South Korea hbkim@dankook.ac.kr songkh@cnu.ac.kr.
authors: Hyeun Bum
authors: HB
authors: Kim
authors: College of Veterinary Medicine, Chungnam National University, Daejeon, South Korea hbkim@dankook.ac.kr songkh@cnu.ac.kr.
authors: Kun-Ho
authors: KH
authors: Song
mesh_terms: D000018:Abomasum / Q000473:pathology*; D000818:Animals; D001419:Bacteria / Q000145:classification* / Q000235:genetics*; D058448:Biota; D002417:Cattle; D016000:Cluster Analysis; D004275:DNA, Ribosomal / Q000737:chemistry / Q000235:genetics; D005243:Feces / Q000382:microbiology*; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D017422:Sequence Analysis, DNA; D013272:Stomach Diseases / Q000662:veterinary*
chemical_list: D004275:DNA, Ribosomal; D012336:RNA, Ribosomal, 16S