title: Unusual Presentation of Epstein-Barr Virus-Positive Diffuse Large B-Cell Non-Hodgkin Lymphoma of the Elderly.
abstract: This report describes the case of a 76-year-old woman diagnosed with Epstein-Barr virus-positive diffuse large B-cell non-Hodgkin lymphoma of the elderly. She had an unusual presentation of the disease with widespread skeletal muscle, masticatory muscle, and parotid gland involvement and the development of interesting erythematous lesions in the neck during chemotherapy. One month after completion of chemotherapy, positron-emission tomography (PET) showed features of persistent lymphoma, but a repeat PET scan a month later showed no active disease. This case reiterates 2 important points: first, to consider lymphoma a differential diagnosis in masticatory muscle enlargement and second, to question false positivity when interpreting post-treatment PET scan results, especially in the absence of clinical disease.
authors: Senior House Officer, Department of Oral and Maxillofacial Surgery, Royal Cornwall Hospital, Truro, UK. Electronic address: bosunhong@gmail.com.
authors: Bosun
authors: B
authors: Hong
authors: Medical Student, University of Birmingham, Birmingham; Trust Grade, Department of Oral and Maxillofacial Surgery, Queens Medical Centre, Nottingham; Locum Staff Grade, Department of Oral and Maxillofacial Surgery, Northampton General Hospital, Northampton, UK.
authors: Vahe
authors: V
authors: Petrosyan
authors: Consultant Hematologist, Department of Hematology, Royal Cornwall Hospital, Truro, UK.
authors: Anton R
authors: AR
authors: Kruger
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D020031:Epstein-Barr Virus Infections / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008410:Masticatory Muscles / Q000473:pathology; D018482:Muscle, Skeletal / Q000473:pathology; D010306:Parotid Gland / Q000473:pathology; D049268:Positron-Emission Tomography