title: A Rare Case of Intra-Endometrial Leiomyoma of Uterus Simulating Degenerated Submucosal Leiomyoma Accompanied by a Large Sertoli-Leydig Cell Tumor.
abstract: A 50-year-old peri-menopausal woman presented with hard palpable mass on her lower abdomen and anemia from heavy menstrual bleeding. Ultrasonography showed a 13×12 cm sized hypoechoic solid mass in pelvis and a 2.5×2 cm hypoechoic cystic mass in uterine endometrium. Abdomino-pelvic computed tomography revealed a hypodense pelvic mass without enhancement, suggesting a leiomyoma of intraligamentary type or sex cord tumor of right ovary with submucosal myoma of uterus. Laparoscopy revealed a large Sertoli-Leydig cell tumor of right ovary with a very rare entity of intra-endometrial uterine leiomyoma accompanied by adenomyosis. The final diagnosis of ovarian sex-cord tumor (Sertoli-Leydig cell), stage Ia with intra-endometrial leiomyoma with adenomyosis, was made. Considering the large size of the tumor and poorly differentiated nature, 6 cycles of chemotherapy with Taxol and Carboplatin regimen were administered. There is neither evidence of major complications nor recurrence during 20 months' follow-up.
authors: Department of Obstetrics and Gynecology, Ewha Womans University School of Medicine, Seoul, Korea.
authors: Kyungah
authors: K
authors: Jeong
authors: Department of Obstetrics and Gynecology, Ewha Womans University School of Medicine, Seoul, Korea. sarahmd@ewha.ac.kr.
authors: Sa Ra
authors: SR
authors: Lee
authors: Department of Pathology, Ewha Womans University School of Medicine, Seoul, Korea.
authors: Sanghui
authors: S
authors: Park
mesh_terms: D062788:Adenomyosis / Q000175:diagnosis* / Q000188:drug therapy; D016190:Carboplatin / Q000627:therapeutic use; D005260:Female; D006801:Humans; D010535:Laparoscopy; D007889:Leiomyoma / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D008595:Menorrhagia; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D017239:Paclitaxel / Q000627:therapeutic use; D018310:Sertoli-Leydig Cell Tumor / Q000175:diagnosis* / Q000188:drug therapy; D016896:Treatment Outcome; D014594:Uterine Neoplasms / Q000175:diagnosis* / Q000188:drug therapy
chemical_list: D016190:Carboplatin; D017239:Paclitaxel
keywords: Sertoli-Leydig cell tumor; heavy menstrual bleeding; intra-endometrial leiomyoma; submucosal myoma