title: Copper-Catalyzed Aerobic C-H Trifluoromethylation of Phenanthrolines.
abstract: Direct C-H trifluoromethylation of heterocycles is a valuable transformation. In particular, nonprecious metal-catalyzed C-H trifluoromethylation processes, which do not proceed through CF3radical species, have been less developed. In this cluster report, a new copper-catalyzed aerobic C-H trifluoromethylation of phenanthrolines is described. This transformation affords trifluoromethylated phenanthrolines that have not been synthesized and preliminary mechanistic studies suggest that the CF3group transfer may occur through cooperative activation.
authors: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors: Cheng-Liang
authors: CL
authors: Zhu
authors: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors: Yong-Qiang
authors: YQ
authors: Zhang
authors: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors: Yong-An
authors: YA
authors: Yuan
authors: Department of Chemistry, Georgia State University, 100 Piedmont Avenue SE, Atlanta, GA 30303, USA.
authors: Hao
authors: H
authors: Xu
keywords: copper; fluorine; heterocycles; oxidation; oxygen