title: Severe rhabdomyolysis secondary to adenovirus infection: case report and literature review.
abstract: A 38-year-old male presented with renal failure in the setting of a flu-like illness. Urinalysis showed myoglobinuria and granular casts. His serum creatine phosphokinase was markedly elevated. He was diagnosed with rhabdomyolysis and was volume resuscitated with normal saline and bicarbonate-containing fluid. Workup included a respiratory viral panel which was positive for adenovirus. Other causes such as trauma, seizure, and intoxicants were excluded. He developed progressive renal failure necessitating hemodialysis. After ~ 4 weeks he recovered renal function and dialysis was discontinued. Viral-induced myopathy should be suspected in patients who present with rhabdomyolysis.
authors: Daniel
authors: D
authors: Tseytlin
authors: Sharon
authors: S
authors: Maynard
mesh_terms: D000258:Adenovirus Infections, Human / Q000175:diagnosis*; D000328:Adult; D003402:Creatine Kinase / Q000097:blood; D005440:Fluid Therapy / Q000379:methods; D006801:Humans; D006947:Hyperkalemia / Q000209:etiology; D054559:Hyperphosphatemia / Q000209:etiology; D006996:Hypocalcemia / Q000209:etiology; D008297:Male; D009212:Myoglobinuria / Q000652:urine; D006435:Renal Dialysis / Q000379:methods; D051437:Renal Insufficiency / Q000628:therapy / Q000821:virology*; D012141:Respiratory Tract Infections / Q000821:virology*; D012206:Rhabdomyolysis / Q000097:blood / Q000652:urine / Q000821:virology*
chemical_list: D003402:Creatine Kinase