title: Acoustic particle palpation for measuring tissue elasticity.
abstract: We propose acoustic particle palpation-the use of sound to press a population of acoustic particles against an interface-as a method for measuring the qualitative and quantitative mechanical properties of materials. We tested the feasibility of this method by emitting ultrasound pulses across a tunnel of an elastic material filled with microbubbles. Ultrasound stimulated the microbubble cloud to move in the direction of wave propagation, press against the distal surface, and cause deformations relevant for elasticity measurements. Shear waves propagated away from the palpation site with a velocity that was used to estimate the material's Young's modulus.
authors: Hasan
authors: H
authors: Koruk
authors: Noninvasive Surgery and Biopsy Laboratory, Department of Bioengineering, Imperial College London , London SW7 2AZ, United Kingdom.
authors: Ahmed
authors: A
authors: El Ghamrawy
authors: Noninvasive Surgery and Biopsy Laboratory, Department of Bioengineering, Imperial College London , London SW7 2AZ, United Kingdom.
authors: Antonios N
authors: 0000-0002-8891-1495
authors: AN
authors: Pouliopoulos
authors: Noninvasive Surgery and Biopsy Laboratory, Department of Bioengineering, Imperial College London , London SW7 2AZ, United Kingdom.
authors: James J
authors: 0000-0002-4850-8204
authors: JJ
authors: Choi