title: Effects of 12 weeks of combined training without caloric restriction on inflammatory markers in overweight girls.
abstract: The objective of the present study was to investigate the effects of combined training without caloric restriction on inflammatory markers in overweight girls. Thirty-three girls (13-17 years) were assigned into overweight training (n = 17) or overweight control (n = 16) groups. Additionally, a normal-weight group (n = 15) was used as control for the baseline values. The combined training programme consisted of six resistance exercises (three sets of 6-10 repetitions at 60-70% 1 RM) followed by 30 min of aerobic exercise (walking/running) at 50-80% VO2peak, performed in the same 60 min session, 3 days/weeks, for 12 weeks. Body composition, dietary intake, aerobic fitness (VO2peak), muscular strength (1 RM), glycaemia, insulinemia, lipid profile and inflammatory markers (C-reactive protein, interleukin-6, tumour necrosis factor-alpha, interleukin-10, leptin, resistin and adiponectin) were measured before and after intervention. There was a significant decrease in body fat (P < 0.01) and increase in fat-free mass (P < 0.01), VO2peak (P < 0.01), 1 RM for leg press (P < 0.01) and bench press (P < 0.01) in the overweight training group. Concomitantly, this group presented significant decreases in serum concentrations of C-reactive protein (P < 0.05) and leptin (P < 0.05), as well as in insulin resistance (P < 0.05) after the experimental period. In conclusion, 12 weeks of combined training without caloric restriction reduced inflammatory markers associated with obesity in overweight girls.
authors: a Department of Physical Education , State University of Maringa , Maringa , Brazil.
authors: Wendell Arthur
authors: WA
authors: Lopes
authors: b Department of Physical Education , University of Parana , Curitiba , Brazil.
authors: Neiva
authors: N
authors: Leite
authors: b Department of Physical Education , University of Parana , Curitiba , Brazil.
authors: Larissa Rosa
authors: LR
authors: da Silva
authors: c Faculty of Physical Education , State University of Campinas , Campinas , Brazil.
authors: Diego Trevisan
authors: DT
authors: Brunelli
authors: c Faculty of Physical Education , State University of Campinas , Campinas , Brazil.
authors: Arthur Fernandes
authors: AF
authors: Gáspari
authors: d Department of Nutrition , University of Parana , Curitiba , Brazil.
authors: Rosana Bento
authors: RB
authors: Radominski
authors: c Faculty of Physical Education , State University of Campinas , Campinas , Brazil.
authors: Mara Patrícia Traina
authors: MP
authors: Chacon-Mikahil
authors: c Faculty of Physical Education , State University of Campinas , Campinas , Brazil.
authors: Cláudia Regina
authors: CR
authors: Cavaglieri
mesh_terms: D054392:Adipokines / Q000097:blood; D000273:Adipose Tissue / Q000378:metabolism; D000293:Adolescent; D015415:Biomarkers; D001823:Body Composition; D001825:Body Fluid Compartments / Q000378:metabolism; D002097:C-Reactive Protein / Q000378:metabolism*; D031204:Caloric Restriction; D016207:Cytokines / Q000097:blood; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000517:prevention & control*; D018836:Inflammation Mediators / Q000097:blood; D007333:Insulin Resistance; D020738:Leptin / Q000097:blood*; D053580:Muscle Strength; D009765:Obesity / Q000150:complications* / Q000378:metabolism / Q000628:therapy; D050177:Overweight; D010101:Oxygen Consumption; D055070:Resistance Training
chemical_list: D054392:Adipokines; D015415:Biomarkers; D016207:Cytokines; D018836:Inflammation Mediators; D020738:Leptin; D002097:C-Reactive Protein
keywords: Obesity; adipokines; adolescents; cytokines; exercise; inflammation