title: Stakeholder attitudes and needs regarding cell-free fetal DNA testing.
abstract: OBJECTIVE
  To explore stakeholder views on cell-free DNA testing and highlight findings important for successful implementation and the provision of best practice in counseling.
  
  
  RESULTS
  Noninvasive tests based on the analysis of cell-free fetal DNA are now widely available in clinical practice and applications are expanding rapidly. It is essential that stakeholder views are considered in order to identify and address any ethical and social issues. We provide an overview of stakeholder viewpoints and then focus on the key issues of informed decision making, test uptake, service delivery and information sources.
  
  
  CONCLUSIONS
  Stakeholders are positive about the introduction of cell-free fetal DNA testing into clinical practice. They describe both practical and psychological benefits arising from tests that are safe and can potentially be performed earlier in pregnancy. Key concerns, which include the potential for these tests to have a negative impact on informed decision making and increased societal pressure to have testing, can be addressed through careful parent-directed counseling. As applications for these tests expand it is increasingly important to develop innovative approaches to facilitate good understanding for parents who are offered noninvasive prenatal testing.
authors: aNorth East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Foundation Trust bGenetics and Genomic Medicine, UCL Institute of Child Health, London, UK.
authors: Melissa
authors: M
authors: Hill
authors: Celine
authors: C
authors: Lewis
authors: Lyn S
authors: LS
authors: Chitty
mesh_terms: D001294:Attitude to Health; D003376:Counseling; D004273:DNA, Neoplasm / Q000097:blood*; D003657:Decision Making; D003695:Delivery of Health Care; D005260:Female; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D010290:Parents; D010817:Physician-Patient Relations; D011247:Pregnancy; D011296:Prenatal Diagnosis
chemical_list: D004273:DNA, Neoplasm