title: Post-Gastric Bypass Hypoglycemia.
abstract: Obesity is a major public health problem worldwide. Obesity-related illnesses, such as coronary heart disease, type 2 diabetes, hypertension, dyslipidemia, stroke, sleep apnea, and several forms of cancer (endometrial, breast, and colon), contribute to a significant number of deaths in the USA. Bariatric surgery, including the Roux-en-Y gastric bypass (RYGB) procedure, has demonstrated significant improvements in obesity and obesity-related co-morbidities and is becoming more popular as the number of obese individuals rises. Despite the reported benefits of bariatric surgery, there are potential complications that physicians need to be aware of as the number of patients undergoing these procedures continues to increase. One challenging and potentially life-threatening complication that to date is not well understood is post-RYGB surgery hypoglycemia (PGBH). In this review, we will present the definition, historical perspective, diagnostic approach, currently available treatment options, and anecdotal assessment and treatment algorithm for this disorder.
authors: Division of Endocrinology, Diabetes, and Metabolism, University of Pittsburgh Medical Center (UPMC), 200 Lothrop Avenue, Pittsburgh, PA, 15225, USA. chevon.rariy@gmail.com.|University of Pittsburgh School of Medicine, 200 Lothrop Avenue, Pittsburgh, PA, 15225, USA. chevon.rariy@gmail.com.
authors: Chevon M
authors: CM
authors: Rariy
authors: Division of Endocrinology, Diabetes, and Metabolism, University of Pittsburgh Medical Center (UPMC), 200 Lothrop Avenue, Pittsburgh, PA, 15225, USA. rometoda@upmc.edu.|University of Pittsburgh School of Medicine, 200 Lothrop Avenue, Pittsburgh, PA, 15225, USA. rometoda@upmc.edu.
authors: David
authors: D
authors: Rometo
authors: Division of Endocrinology, Diabetes, and Metabolism, University of Pittsburgh Medical Center (UPMC), 200 Lothrop Avenue, Pittsburgh, PA, 15225, USA. mtk7@pitt.edu.|University of Pittsburgh School of Medicine, 200 Lothrop Avenue, Pittsburgh, PA, 15225, USA. mtk7@pitt.edu.
authors: Mary
authors: M
authors: Korytkowski
mesh_terms: D015390:Gastric Bypass / Q000009:adverse effects; D052216:Glucagon-Like Peptide 1 / Q000378:metabolism; D006801:Humans; D006973:Hypertension / Q000150:complications; D007003:Hypoglycemia / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology; D054795:Incretins / Q000378:metabolism; D009765:Obesity / Q000150:complications
chemical_list: D054795:Incretins; D052216:Glucagon-Like Peptide 1
keywords: Bariatric surgery; Gastric bypass; Glucagon-like peptide-1; Hypoglycemia; Incretins; Nesidioblastosis; Obesity