title: Impact of Prostate Cancer Diagnosis on Noncancer Hospitalizations Among Elderly Medicare Beneficiaries With Incident Prostate Cancer.
abstract: The purpose of this study was to analyze the impact of cancer diagnosis on noncancer hospitalizations (NCHs) by comparing these hospitalizations between the precancer and postcancer periods in a cohort of fee-for-service Medicare beneficiaries with incident prostate cancer.
  
  
  
  A population-based retrospective cohort study was conducted using the SEER-Medicare linked database for 2000 through 2010. The study cohort consisted of 57,489 elderly men (aged ≥ 67 years) with incident prostate cancer. NCHs were identified in 6 periods (t1-t6) before and after the incidence of prostate cancer. Each period consisted of 120 days. For each period, NCHs were defined as inpatient admissions with primary diagnosis codes not related to prostate cancer, prostate cancer-related procedures, or bowel, sexual, and urinary dysfunction. Bivariate and multivariate comparisons on rates of NCHs between the precancer and postcancer periods accounted for the repeated measures design.
  
  
  
  The rate of NCHs was higher during the postcancer period (5.1%) compared with the precancer period (3.2%). In both unadjusted and adjusted models, elderly men were 37% (odds ratio [OR], 1.37; 95% CI, 1.32, 1.41) and 38% (adjusted OR, 1.38; 95% CI, 1.33, 1.46) more likely to have any NCHs during the postcancer period compared with the precancer period.
  
  
  
  Elderly men with prostate cancer had a significant increase in the risk of NCHs after the diagnosis of prostate cancer. This study highlights the need to design interventions for reducing the excess NCHs after prostate cancer diagnosis among elderly men.
authors: Department of Pharmaceutical Systems and Policy, School of Pharmacy, School of Medicine, West Virginia University, Morgantown, West Virginia
authors: Amit D
authors: AD
authors: Raval
authors: Department of Pharmaceutical Systems and Policy, School of Pharmacy, School of Medicine, West Virginia University, Morgantown, West Virginia
authors: Suresh
authors: S
authors: Madhavan
authors: Department of Radiation Oncology, School of Medicine, West Virginia University, Morgantown, West Virginia
authors: Malcolm D
authors: MD
authors: Mattes
authors: Department of Urology, School of Medicine, West Virginia University, Morgantown, West Virginia
authors: Mohamad
authors: M
authors: Salkini
authors: Department of Pharmaceutical Systems and Policy, School of Pharmacy, School of Medicine, West Virginia University, Morgantown, West Virginia
authors: Usha
authors: U
authors: Sambamoorthi
mesh_terms: D000368:Aged; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D008297:Male; D006278:Medicare; D016017:Odds Ratio; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D012189:Retrospective Studies; D018426:SEER Program; D014481:United States