title: Naive versus Primed: It's Now Three-Dimensional.
abstract: We are only beginning to understand the higher-order chromatin structure of pluripotent stem cells and its relevance to cell fate. Three recent studies used different approaches to reconstruct the 3D chromatin landscape of naive and primed pluripotent cells, unveiling common features as well as differences between these two states.
authors: Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
authors: Zong
authors: Z
authors: Wei
authors: The Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of USC, University of Southern California, Los Angeles, CA 90042, USA. Electronic address: wangelu@usc.edu.
authors: Wange
authors: W
authors: Lu
mesh_terms: D002454:Cell Differentiation; D002843:Chromatin; D053595:Embryonic Stem Cells; D039904:Pluripotent Stem Cells
chemical_list: D002843:Chromatin