title: Effects of verbenalin on prostatitis mouse model.
abstract: The aim of this study was to observe the treatment characteristics of verbenalin on a prostatitis mouse model. Give Xiaozhiling injection in the prostate locally to make a prostatitis mouse model. High, medium and low doses of verbenalin were each given to different mouse groups. The amount of water was determined in 14th, 28th. The number of white cells and lecithin corpuscle density in prostatic fluid were determined. Morphological changes in the prostate, testis, epididymis and kidney were detected. Compared with the model control group, the mice treated with high, medium and low doses of verbenalin had significantly increased amounts of water, and prostate white blood cell count and prostate volume density (Vv) were decreased significantly, the density of lecithin corpuscle score increased, and pathologic prostatitis changes were significantly reduced. Pathological change in the testis was significantly reduced and the change in the epididymis was obviously reduced. The thymic cortex thickness and the number of lymphocytes increased significantly and could reduce the renal pathological changes in potential. Verbenalin has a good therapeutic effect on the prostatitis mouse model.
authors: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China.
authors: Mingsan
authors: M
authors: Miao
authors: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China.
authors: Lin
authors: L
authors: Guo
authors: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China.
authors: Xiaoli
authors: X
authors: Yan
authors: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China.
authors: Tan
authors: T
authors: Wang
authors: Henan University of Traditional Chinese Medicine, Zhengzhou 450008, Henan Province, China.
authors: Zuming
authors: Z
authors: Li
keywords: Mouse model; Prostatitis; Verbenalin