title: Three-dimensional modeling of flow and deformation in idealized mild and moderate arterial vessels.
abstract: Three-dimensional numerical calculations of mild and moderate stenosed blood vessels have been performed. Large eddy simulation through a dynamic subgrid scale Smagorinsky model is applied to model the transitional and turbulent pulsatile flow. For the compliant stenosed model, fluid-structure interaction is realized through a two-way coupling between the fluid flow and the deforming vessel through the change in the external diameter due to the increment of circumferential pressure via a novel moving boundary approach. Model predictions compare very well against measured and numerical data for the centerline velocities, thickness of the flow separation zones and radial wall displacements.
authors: a School of Mechanical and Manufacturing Engineering , University of New South Wales , Sydney , Australia.
authors: Xi
authors: X
authors: Gu
authors: a School of Mechanical and Manufacturing Engineering , University of New South Wales , Sydney , Australia.|b Australian Nuclear Science and Technology Organisation (ANSTO) , Kirrawee DC , NSW 2232 , Australia.
authors: Guan Heng
authors: GH
authors: Yeoh
authors: a School of Mechanical and Manufacturing Engineering , University of New South Wales , Sydney , Australia.
authors: Victoria
authors: V
authors: Timchenko
mesh_terms: D000465:Algorithms; D001158:Arteries / Q000503:physiopathology*; D001783:Blood Flow Velocity; D003198:Computer Simulation; D023921:Coronary Stenosis / Q000503:physiopathology; D018056:Hemorheology / Q000502:physiology*; D006801:Humans; D021621:Imaging, Three-Dimensional; D008955:Models, Cardiovascular; D009716:Numerical Analysis, Computer-Assisted; D013314:Stress, Mechanical
keywords: Pulsatile flow; large eddy simulation; mild stenosis; moderate stenosis; transition to turbulence