title: Green organocatalytic α-hydroxylation of ketones.
abstract: An efficient and green method for the α-hydroxylation of substituted ketones has been developed. This method includes the in situ conversion of various ketones into the corresponding silyl enol ethers and their oxidation to the corresponding α-hydroxy ketones. Two protocols have been established leading either to protected α-hydroxy carbonyls or free α-hydroxy ketones. Both procedures are easy to follow and lead to good to high yields for a variety of ketones.
authors: Laboratory of Organic Chemistry, Department of Chemistry, National and Kapodestrian University of Athens, Panepistimiopolis, Athens 15771, Greece. ckokotos@chem.uoa.gr.
authors: Errika
authors: E
authors: Voutyritsa
authors: Alexis
authors: A
authors: Theodorou
authors: Christoforos G
authors: CG
authors: Kokotos