title: Hierarchical porous microspheres of the Co3O4@graphene with enhanced electrocatalytic performance for electrochemical biosensors.
abstract: The integration of organic and inorganic building blocks into hierarchical porous architectures makes potentially desirable electrocatalytic materials in many electrochemical applications due to their combination of attractive qualities of dissimilar components and well-constructed charge transfer pathways. Herein, we demonstrate the preparation of the hierarchical porous Co3O4@graphene (Co3O4@G) microspheres by one-step hydrothermal method to achieve high electrocatalytic performance for enzyme-free biosensor applications. The obtained Co3O4@G microspheres are consisted of the interconnected networks of Co3O4and graphene sheets, and thus provide large accessible active sites through porous structure, while graphene sheets offer continuous electron pathways for efficient electrocatalytic reaction of Co3O4. These structural merits with synergy effect of Co3O4and graphene lead to a high performance of enzyme-free detection for glucose: high sensitivity, good selectivity, and remarkable stability.
authors: Department of Nano Bio Research, National NanoFab Center (NNFC), Daejeon 305-806, Republic of Korea.
authors: MinHo
authors: M
authors: Yang
authors: Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.
authors: Jae-Min
authors: JM
authors: Jeong
authors: Department of Nano Bio Research, National NanoFab Center (NNFC), Daejeon 305-806, Republic of Korea.
authors: Kyoung G
authors: KG
authors: Lee
authors: Department of Chemical & Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon 305-701, Republic of Korea.
authors: Do Hyun
authors: DH
authors: Kim
authors: Department of Nano Bio Research, National NanoFab Center (NNFC), Daejeon 305-806, Republic of Korea. Electronic address: sjlee@nnfc.re.kr.
authors: Seok Jae
authors: SJ
authors: Lee
authors: Department of Chemical Engineering, Kangwon National University, Samcheok 245-711, Republic of Korea. Electronic address: bgchoi@kangwon.ac.kr.
authors: Bong Gill
authors: BG
authors: Choi
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation; D001786:Blood Glucose / Q000032:analysis*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D056656:Lab-On-A-Chip Devices; D057230:Limit of Detection; D008863:Microspheres; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry*; D016062:Porosity
chemical_list: D001786:Blood Glucose; D010087:Oxides; D003035:Cobalt; D006108:Graphite; C060728:cobalt oxide
keywords: Electrochemical biosensor; Graphene; Metal oxide; Nanocomposite