title: Covalent functionalization of single-walled carbon nanotubes with polytyrosine: Characterization and analytical applications for the sensitive quantification of polyphenols.
abstract: This work reports the synthesis and characterization of single-walled carbon nanotubes (SWCNT) covalently functionalized with polytyrosine (Polytyr); the critical analysis of the experimental conditions to obtain the efficient dispersion of the modified carbon nanotubes; and the analytical performance of glassy carbon electrodes (GCE) modified with the dispersion (GCE/SWCNT-Polytyr) for the highly sensitive quantification of polyphenols. Under the optimal conditions, the calibration plot for the amperometric response of gallic acid (GA) shows a linear range between 5.0 × 10(-7) and 1.7 × 10(-4) M, with a sensitivity of (518 ± 5) m AM(-1) cm(-2), and a detection limit of 8.8 nM. The proposed sensor was successfully used for the determination of total polyphenolic content in tea extracts.
authors: INFIQC, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Ciudad Universitaria, 5000 Córdoba, Argentina.
authors: Marcos
authors: M
authors: Eguílaz
authors: INFIQC, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Ciudad Universitaria, 5000 Córdoba, Argentina.
authors: Alejandro
authors: A
authors: Gutiérrez
authors: INFIQC, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Ciudad Universitaria, 5000 Córdoba, Argentina.
authors: Fabiana
authors: F
authors: Gutierrez
authors: Grupo de nanoestructuras de carbono y Nanotecnología, Departamento de Nanotecnología, Instituto de Carboquímica (CSIC), 50018 Zaragoza, Spain.
authors: Jose Miguel
authors: JM
authors: González-Domínguez
authors: Grupo de nanoestructuras de carbono y Nanotecnología, Departamento de Nanotecnología, Instituto de Carboquímica (CSIC), 50018 Zaragoza, Spain.
authors: Alejandro
authors: A
authors: Ansón-Casaos
authors: Grupo de nanoestructuras de carbono y Nanotecnología, Departamento de Nanotecnología, Instituto de Carboquímica (CSIC), 50018 Zaragoza, Spain.
authors: Javier
authors: J
authors: Hernández-Ferrer
authors: INFIQC, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Ciudad Universitaria, 5000 Córdoba, Argentina.
authors: Nancy F
authors: NF
authors: Ferreyra
authors: Grupo de nanoestructuras de carbono y Nanotecnología, Departamento de Nanotecnología, Instituto de Carboquímica (CSIC), 50018 Zaragoza, Spain. Electronic address: mtmartinez@icb.csic.es.
authors: María T
authors: MT
authors: Martínez
authors: INFIQC, Departamento de Fisicoquímica, Facultad de Ciencias Químicas, Ciudad Universitaria, 5000 Córdoba, Argentina. Electronic address: grivas@fcq.unc.edu.ar.
authors: Gustavo
authors: G
authors: Rivas
mesh_terms: D004566:Electrodes; D005707:Gallic Acid / Q000737:chemistry; D015394:Molecular Structure; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010455:Peptides / Q000737:chemistry*; D059808:Polyphenols / Q000032:analysis*
chemical_list: D037742:Nanotubes, Carbon; D010455:Peptides; D059808:Polyphenols; C017663:polytyrosine; D005707:Gallic Acid
keywords: Covalent functionalization; Gallic acid; Polytyrosine; Single-walled carbon nanotubes