title: Model of human cardiovascular system with a loop of autonomic regulation of the mean arterial pressure.
abstract: A model of human cardiovascular system is proposed which describes the main heart rhythm, the regulation of heart function and blood vessels by the autonomic nervous system, baroreflex, and the formation of arterial blood pressure. The model takes into account the impact of respiration on these processes. It is shown that taking into account nonlinearity and introducing the autonomous loop of mean arterial blood pressure in the form of self-oscillating time-delay system allow to obtain the model signals whose statistical and spectral characteristics are qualitatively and quantitatively similar to those for experimental signals. The proposed model demonstrates the phenomenon of synchronization of mean arterial pressure regulatory system by the signal of respiration with the basic period close to 10 seconds, which is observed in the physiological experiments.
authors: Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia.
authors: Anatoly S
authors: AS
authors: Karavaev
authors: Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia.
authors: Yurii M
authors: YM
authors: Ishbulatov
authors: Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia.
authors: Vladimir I
authors: VI
authors: Ponomarenko
authors: Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia.
authors: Mikhail D
authors: MD
authors: Prokhorov
authors: Department of New Cardiological Informational Technologies, Research Institute of Cardiology, Saratov State Medical University n.a. V. I. Razumovsky, Saratov, Russia.
authors: Vladimir I
authors: VI
authors: Gridnev
authors: Saratov Branch of the Institute of Radio Engineering and Electronics of Russian Academy of Sciences, Saratov, Russia.
authors: Boris P
authors: BP
authors: Bezruchko
authors: Department of New Cardiological Informational Technologies, Research Institute of Cardiology, Saratov State Medical University n.a. V. I. Razumovsky, Saratov, Russia; Department of Surgical Treatment for Interactive Pathology, Bakulev Scientific Center for Cardiovascular Surgery, Moscow, Russia. Electronic address: kiselev@cardio-it.ru.
authors: Anton R
authors: AR
authors: Kiselev
mesh_terms: D062186:Arterial Pressure / Q000502:physiology*; D001341:Autonomic Nervous System / Q000502:physiology*; D017704:Baroreflex / Q000502:physiology*; D002320:Cardiovascular Physiological Phenomena; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D008962:Models, Theoretical
keywords: Arterial pressure; autonomic regulation; baroreflex; cardiovascular system