title: Plasmacytoma-like Posttransplant Lymphoproliferative Disorder in a Pediatric Heart Transplant Recipient.
abstract: Posttransplant lymphoproliferative disorder (PTLD) is a diversely manifesting group of lymphoid or plasmacytic proliferations found in solid organ and bone marrow transplant recipients. PTLD occurs as a result of immunosuppression and is often driven by the Epstein Barr virus. Although most commonly of B-cell origin, similar to B-cell lymphomas, PTLD can rarely present as a plasmacytic process, resembling multiple myeloma. Although more common in adults, 8 cases of plasmacytoma-like PTLD have been reported in pediatric renal and combined small bowel-liver transplant recipients. Here, we present a rare report of a plasmacytoma-like PTLD case in a pediatric heart transplant recipient.
authors: *Department of Pediatrics, Division of Hematology-Oncology ‡Department of Pediatrics, Division of Cardiology, University of Virginia Children's Hospital, Charlottesville, VA †Department of Laboratory Medicine, University of California, San Francisco, CA §Department of Pediatrics, Division of Cardiology, Children's Hospital at Montefiore, Bronx, NY ∥Department of Pediatrics, Division of Hematology-Oncology, Children's Hospital of the King's Daughters, Norfolk, VA.
authors: Sara Rhodes
authors: SR
authors: Proctor Short
authors: Steven L
authors: SL
authors: Cook
authors: Andrew S
authors: AS
authors: Kim
authors: Jacqueline M
authors: JM
authors: Lamour
authors: Eric J
authors: EJ
authors: Lowe
authors: William C
authors: WC
authors: Petersen
mesh_terms: D001021:Aortic Valve / Q000002:abnormalities; D000082882:Bicuspid Aortic Valve Disease; D002311:Cardiomyopathy, Dilated / Q000209:etiology / Q000601:surgery; D002675:Child, Preschool; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006330:Heart Defects, Congenital / Q000150:complications; D016027:Heart Transplantation / Q000009:adverse effects*; D006349:Heart Valve Diseases / Q000150:complications / Q000151:congenital; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008232:Lymphoproliferative Disorders / Q000276:immunology*; D010954:Plasmacytoma / Q000276:immunology*
chemical_list: D007166:Immunosuppressive Agents