title: Macular Thickness in Myopia: An OCT Study of Young Chinese Patients.
abstract: To investigate macular thickness (MT) in young myopic Chinese patients using Spectralis optical coherence tomography (OCT) and to assess its association with gender, axial length (AL), spherical equivalent (SE), and intraocular pressure (IOP).
  
  
  
  Included in this study were 133 myopic Chinese patients, aged 18-30 years. All underwent complete ophthalmic examinations and Spectralis OCT. Inner, central, and outer foveal regions of the macula were measured.
  
  
  
  The central fovea was the thinnest of the three macular regions (mean thickness, 250.1 ± 15.3 μm). Women had consistently thinner MTs than did men, except in the outer superior and inferior areas. Central foveal thickness (CFT) was positively correlated with AL and negatively correlated with SE. In the inner and outer regions, MT was positively correlated with SE. AL was negatively correlated with MT in all quadrants of the inner and outer sectors, but not the inner superior and outer nasal areas. No macular measurement was significantly correlated with age or IOP in either gender.
  
  
  
  Variables affecting MT should be considered when evaluating SD-OCT data in young myopic Chinese patients, with and without retinal diseases.
authors: a Department of Ophthalmology , Shanghai Jiaotong University Affiliated Sixth People's Hospital , Shanghai , China.
authors: Ming-Hui
authors: MH
authors: Zhao
authors: a Department of Ophthalmology , Shanghai Jiaotong University Affiliated Sixth People's Hospital , Shanghai , China.
authors: Qiang
authors: Q
authors: Wu
authors: a Department of Ophthalmology , Shanghai Jiaotong University Affiliated Sixth People's Hospital , Shanghai , China.
authors: Ping
authors: P
authors: Hu
authors: a Department of Ophthalmology , Shanghai Jiaotong University Affiliated Sixth People's Hospital , Shanghai , China.
authors: Li-Li
authors: LL
authors: Jia
mesh_terms: D000293:Adolescent; D000328:Adult; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007429:Intraocular Pressure; D008266:Macula Lutea / Q000473:pathology*; D008297:Male; D009216:Myopia / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult
keywords: Axial length; gender; myopia; optical coherence tomography; spherical equivalence refraction