title: Risk factors for pulmonary hypertension in patients receiving maintenance peritoneal dialysis.
abstract: We investigated the risk factors for pulmonary hypertension (PH) in patients receiving maintenance peritoneal dialysis (MPD). A group of 180 end-stage renal disease patients (124 men and 56 women; mean age: 56.43±8.36) were enrolled in our study, which was conducted between January 2009 and June 2014. All of the patients received MPD treatment in the Dialysis Center of the Second Affiliated Hospital of Soochow University. Clinical data, laboratory indices, and echocardiographic data from these patients were collected, and follow-ups were scheduled bi-monthly. The incidence and relevant risk factors of PH were analyzed. The differences in measurement data were compared by t-test and enumeration data were compared with the χ2 test. Among the 180 patients receiving MPD, 60 were diagnosed with PH. The remaining 120 were regarded as the non-PH group. Significant differences were observed in the clinical data, laboratory indices, and echocardiographic data between the PH and non-PH patients (all P<0.05). Furthermore, hypertensive nephropathy patients on MPD showed a significantly higher incidence of PH compared with non-hypertensive nephropathy patients (P<0.05). Logistic regression analysis showed that the proportion of internal arteriovenous fistula, C-reactive protein levels, and ejection fraction were the highest risk factors for PH in patients receiving MPD. Our study shows that there is a high incidence of PH in patients receiving MPD and hypertensive nephropathy patients have an increased susceptibility to PH.
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: Y
authors: Y
authors: Zeng
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: D D
authors: DD
authors: Yang
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: S
authors: S
authors: Feng
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: H Y
authors: HY
authors: Shen
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: Z
authors: Z
authors: Wang
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: S
authors: S
authors: Jiang
authors: Department of Nephrology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: Y B
authors: YB
authors: Shi
authors: Department of Hematology, The Second Affiliated Hospital of Soochow University, Suzhou, China.
authors: J X
authors: JX
authors: Fu
mesh_terms: D000368:Aged; D001164:Arteriovenous Fistula / Q000150:complications*; D002097:C-Reactive Protein / Q000032:analysis; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000453:epidemiology / Q000209:etiology*; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000150:complications / Q000628:therapy; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010530:Peritoneal Dialysis / Q000009:adverse effects*; D010758:Phosphorus / Q000097:blood; D011446:Prospective Studies; D012307:Risk Factors
chemical_list: D020097:Natriuretic Peptide, Brain; D010758:Phosphorus; D002097:C-Reactive Protein