title: Cortical Plasticity in the Setting of Brain Tumors.
abstract: Cortical reorganization of function due to the growth of an adjacent brain tumor has clearly been demonstrated in a number of surgically proven cases. Such cases demonstrate the unmistakable implications for the neurosurgical treatment of brain tumors, as the cortical function may not reside where one may initially suspect based solely on the anatomical magnetic resonance imaging (MRI). Consequently, preoperative localization of eloquent areas adjacent to a brain tumor is necessary, as this may demonstrate unexpected organization, which may affect the neurosurgical approach to the lesion. However, in interpreting functional MRI studies, the interpreting physician must be cognizant of artifacts, which may limit the accuracy of functional MRI in the setting of brain tumors.
authors: *Functional MRI Laboratory †Department of Radiology ‡Brain Tumor Canter §Department of Medical Physics, Memorial Sloan-Kettering Cancer Center, New York ¶Department of Psychology, Cornell University, Ithaca, NY.
authors: Ryan A
authors: RA
authors: Fisicaro
authors: Ethan
authors: E
authors: Jost
authors: Katharina
authors: K
authors: Shaw
authors: Nicole Petrovich
authors: NP
authors: Brennan
authors: Kyung K
authors: KK
authors: Peck
authors: Andrei I
authors: AI
authors: Holodny
mesh_terms: D001931:Brain Mapping / Q000379:methods; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery*; D002540:Cerebral Cortex / Q000503:physiopathology* / Q000601:surgery; D004558:Electric Stimulation / Q000379:methods*; D006801:Humans; D064795:Intraoperative Neurophysiological Monitoring / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009473:Neuronal Plasticity; D011300:Preoperative Care / Q000379:methods