title: [GENETIC AND EPIGENETIC DETERMINANTS OF ALZHEIMER'S DISEASE].
abstract: Alzheimer's disease (AD) is one of the most important economic, medical and social problems in modern society. Numerous studies have highlighted the role of genetic and epigenetic factors in this disease. Increased risk of AD is associated with certain polymorphic variants of the APOE gene, as well as some other, less affecting genes. In the review, recent studies demonstrating the role of genetic and epigenetic factors in the etiology and pathogenesis of AD are discussed.
authors: Ye V
authors: YV
authors: Dyukov
authors: N Yu
authors: NY
authors: Bachinskaya
authors: V A
authors: VA
authors: Cholin
authors: A K
authors: AK
authors: Kolyada
authors: A M
authors: AM
authors: Vaiserman
mesh_terms: D000375:Aging / Q000235:genetics*; D000544:Alzheimer Disease / Q000235:genetics*; D057890:Epigenomics / Q000379:methods*; D020022:Genetic Predisposition to Disease; D006801:Humans