title: [Peptide Regulation of Metabolic Processes under Hypercholesterinemia Conditions of an Organism].
abstract: The participation of short glyproline peptides in regulating the metabolic processes of the body has been established. Experimental hypercholesterolemia and the development of metabolic syndrome in rats was caused by including foods with excess animal fat and carbohydrates in the diet, which eventually led to increased levels of cholesterol, triglycerides, and the atherogenic lipoproteins; hypercoagulation; and increased blood sugar. It was noted that glyprolines with different structures possess a unique combined effect on fat and carbohydrate metabolism, normalizing the characteristics of the lipid profile and blood sugar and protecting the organisms of animals from increased blood clotting. The idea of peptide regulation of the hemostatic system and metabolism of fats and carbohydrates in the development of metabolic syndrome was formulated.
authors: L A
authors: LA
authors: Lyapina
authors: M E
authors: ME
authors: Grigor'eva
authors: T Yu
authors: TY
authors: Obergan
authors: T A
authors: TA
authors: Shubina
authors: L A
authors: LA
authors: Andreeva
authors: N F
authors: NF
authors: Myasoedov
mesh_terms: D000818:Animals; D001777:Blood Coagulation / Q000187:drug effects; D059305:Diet, High-Fat / Q000009:adverse effects; D004151:Dipeptides / Q000494:pharmacology*; D006937:Hypercholesterolemia / Q000209:etiology / Q000378:metabolism*; D050356:Lipid Metabolism / Q000187:drug effects*; D008297:Male; D051381:Rats
chemical_list: D004151:Dipeptides; C015248:glycylproline