title: Steroid-Responsive Encephalopathy, Dropped Head Syndrome, and Hypertension in a Toddler: Is There a Clue?
abstract: BACKGROUND
  Paraneoplastic manifestations may provide an early clue to underlying malignancies in children.
  
  
  METHODS
  We describe a 3-year-old girl with an unusual neurological paraneoplastic syndrome of steroid-responsive encephalopathy and dropped head syndrome associated with paraspinal neuroblastoma.
  
  
  RESULTS
  Cranial neuroimaging, metabolic screen, and thyroid functions were normal. Abdominal imaging identified a paraspinal neuroblastoma. Encephalopathy and neck extensor weakness responded to pulse corticosteroids followed by tumor resection.
  
  
  CONCLUSIONS
  This is a unique child with paraneoplastic steroid-responsive encephalopathy and dropped head syndrome in association with neuroblastoma.
authors: Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors: Arushi Gahlot
authors: AG
authors: Saini
authors: Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors: Jitendra Kumar
authors: JK
authors: Sahu
authors: Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors: Saptharishi Lalgudi
authors: SL
authors: Ganeshan
authors: Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors: Kushaljit Singh
authors: KS
authors: Sodhi
authors: Department of Pediatric Surgery, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
authors: Katragadda Laxmi Narayan
authors: KL
authors: Rao
authors: Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India. Electronic address: doctorpratibhasinghi@gmail.com.
authors: Pratibha
authors: P
authors: Singhi
mesh_terms: D001927:Brain Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002675:Child, Preschool; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D009135:Muscular Diseases / Q000150:complications / Q000000981:diagnostic imaging / Q000188:drug therapy*; D013256:Steroids / Q000627:therapeutic use*; D015898:Tomography Scanners, X-Ray Computed
chemical_list: D013256:Steroids
keywords: cardiomyopathy; dropped head syndrome; encephalopathy; neuroblastoma; paraneoplastic