title: Primary angiosarcoma of the breast.
abstract: Primary angiosarcoma (AS) of the breast is a rare neoplasia that is not related to radiation exposure. It represents less than 0.05% of all malignant breast tumors. This lesion is characterized by aggressive patterns and poor prognosis and by the absence of typical features at radiologic examination. Currently there are not evidence-based guidelines regarding surgical and adjuvant treatment for this tumor even though wide surgical resection followed by chemo- radiotherapy appears to improve both disease free survival and overall survival. The aim of this study was to analyze the available series of AS patients suggesting the most reliable treatment options for this rare neoplasia.
authors: Department of Senology, Asur Marche Area Vasta 1, Santa Maria della Misericordia, Via Comandino 70, Urbino, Italy. Electronic address: Daniele.bordoni@sanita.marche.it.
authors: Daniele
authors: D
authors: Bordoni
authors: Department of Plastic and Reconstructive Surgery, University of Ancona, Via Conca 71, Ancona, Italy. Electronic address: Elisa.bolletta.md@gmail.com.
authors: Elisa
authors: E
authors: Bolletta
authors: Breast Surgery Unit, IRCCS-Arcispedale Santa Maria Nuova, Viale Risorgimento 80, 42123 Reggio Emilia, Italy. Electronic address: giuseppe.falco@asmn.re.it.
authors: Giuseppe
authors: G
authors: Falco
authors: Department of Plastic Surgery, Hand Surgery and Microsurgery, San Gerardo Hospital, Monza, Milano, Italy. Electronic address: p.cadenelli@hotmail.it.
authors: Pierfrancesco
authors: P
authors: Cadenelli
authors: Department of Clinical Medicine and Surgery. University of Naples "Federico II", Naples, Italy. Electronic address: nicolarocco2003@gmail.com.
authors: Nicola
authors: N
authors: Rocco
authors: Department of Plastic and Reconstructive Surgery, The Talpiot Medical Leadership Program, Sheba Medical Center, Israel. Electronic address: arieltessonemd@me.com.
authors: Ariel
authors: A
authors: Tessone
authors: Department of Oncology, Asur Marche Area Vasta 1, Santa Maria della Misericordia, Via Comandino 70, Urbino, Italy. Electronic address: guarino@sanita.marche.it.
authors: Stefania
authors: S
authors: Guarino
authors: Department of Gastroenterology, Endocrinology and Surgery, AO "Federico II", Naples, Italy. Electronic address: antonello.accurso@unina.it.
authors: Antonello
authors: A
authors: Accurso
authors: Department of Clinical Medicine and Surgery. University of Naples "Federico II", Naples, Italy. Electronic address: bramato@unina.it.
authors: Bruno
authors: B
authors: Amato
authors: Department of Senology, Asur Marche Area Vasta 1, Santa Maria della Misericordia, Via Comandino 70, Urbino, Italy. Electronic address: Daniele.bordoni@sanita.marche.it.
authors: Cesare
authors: C
authors: Magalotti
keywords: Angiosarcoma; Breast cancer; Breast sarcomas