title: Novel small molecule inhibitors of the OLIG2 transcription factor: promising new therapeutics for glioblastoma.
authors: Curtana Pharmaceuticals, 1624 Headway Circle, Austin, TX 78754, USA.
authors: Gordon
authors: G
authors: Alton
authors: John Wayne Cancer Institute, Santa Monica, CA 90404, USA.
authors: Santosh
authors: S
authors: Kesari
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D051792:Basic Helix-Loop-Helix Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D055808:Drug Discovery; D005909:Glioblastoma / Q000188:drug therapy / Q000378:metabolism*; D006801:Humans; D058990:Molecular Targeted Therapy; D009419:Nerve Tissue Proteins / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism*; D000076104:Oligodendrocyte Transcription Factor 2
chemical_list: D000970:Antineoplastic Agents; D051792:Basic Helix-Loop-Helix Proteins; D009419:Nerve Tissue Proteins; D000076104:Oligodendrocyte Transcription Factor 2; C405708:OLIG2 protein, human
keywords: OLIG2; cancer stem cell; glioblastoma; pharmacophore; transcription factor; tumor progenitor