title: The biopolymer sugarcane as filling material of critical defects in rats.
abstract: OBJECTIVE
  To evaluate the effects of particulate (granule-shaped) SCB on bone repair relating it to its biocompatibility and bone neoformation.
  
  
  METHODS
  Thirty Wistar rats were submitted to a one 7-mm-diameter defect and divided equally into three experimental groups, with two different postoperative times of evaluation, 90 and 120 days. Each calvaria defect was filled up with clot (control group), particulated autogenous bone or granulated SCB. Five animals of each group were assessed at 90 and 120 days after surgery. In these two periods, histological and histometric analysis were obtained.
  
  
  RESULTS
  The clot group showed a bone resorption trend while the autogenous bone group a bone repair trend. However in the SCB group, the critical defect filled up only with fibrous connective tissue and presented none bone neoformation.
  
  
  CONCLUSIONS
  The sugarcane biopolymer when used in critical size defects was a biocompatible material and proved to be a good material to fill bone cavities, keeping them as uniform areas filled with soft tissue and avoiding the tissue shrinkage.
authors: Universidade de Pernambuco, Recife, PE, Brazil.
authors: Taciana Cavalcanti de
authors: TC
authors: Abreu
authors: Department of Surgery, UFPE, Recife, PE, Brazil.
authors: Rodrigo Pontes de
authors: RP
authors: Lima
authors: Department of Surgery, Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors: Veridiana Sales Barbosa de
authors: VS
authors: Souza
authors: Department of Anatomy, UFPE, Recife, PE, Brazil.
authors: Olavio
authors: O
authors: Campos Júnior
authors: Department of Surgery, UFPE, Recife, PE, Brazil.
authors: Amanda Vasconcelos de
authors: AV
authors: Albuquerque
authors: Department of Surgery, UFPE, Recife, PE, Brazil.
authors: José Lamartine de Andrade
authors: JL
authors: Aguiar
authors: Pernambuco College of Dentistry, UPE, Recife, PE, Brazil.
authors: Emanuel Sávio de Souza
authors: ES
authors: Andrade
authors: Pernambuco College of Dentistry, UPE, Recife, PE, Brazil.
authors: Belmiro Cavalcanti do Egito
authors: BC
authors: Vasconcelos
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000627:therapeutic use*; D001704:Biopolymers / Q000008:administration & dosage / Q000627:therapeutic use; D001861:Bone Regeneration / Q000187:drug effects; D018786:Bone Substitutes; D016025:Bone Transplantation / Q000379:methods*; D008297:Male; D010012:Osteogenesis / Q000187:drug effects*; D017208:Rats, Wistar; D031786:Saccharum / Q000737:chemistry*; D012886:Skull / Q000293:injuries* / Q000473:pathology / Q000601:surgery; D013997:Time Factors
chemical_list: D001672:Biocompatible Materials; D001704:Biopolymers; D018786:Bone Substitutes