title: [CORRECTION OF HEMOSTASIS WITH BLOOD PRODUCTS IN THE SURGICAL TREATMENT OF CONGENITAL HEART DISEASE IN INFANTS AND YOUNG CHILDREN].
abstract: The article deals with the safety and efficiency of recombinant activated factor VII (Coagil VII, Russia) and prothrombin complex concentrate (protromplex-600, Baxter Austria) in the neonatal and pediatric cardiac surgery. The study included 56 children aged from 7 days to 5.5 years underwent surgery with cardiopulmonary bypass for congenital heart defects repair. Clinical and laboratory evidences suggest that Coagil VII and protromplex-600 effective for bleeding stop. The drugs have no negative impact on hemodynamics. We did not identify allergic reactions and thrombosis associated with the introduction of drugs in the pen operative period.
authors: M M
authors: MM
authors: Rybka
authors: N N
authors: NN
authors: Samsonova
authors: L G
authors: LG
authors: Klimovich
authors: E A
authors: EA
authors: Rogalskaya
authors: D Ya
authors: DY
authors: Khichagov
authors: F E
authors: FE
authors: Tataryan
mesh_terms: D006348:Cardiac Surgical Procedures / Q000379:methods*; D002675:Child, Preschool; D003029:Coagulants / Q000008:administration & dosage / Q000627:therapeutic use*; D004338:Drug Combinations; D005112:Extracorporeal Circulation; D005164:Factor IX / Q000008:administration & dosage / Q000627:therapeutic use*; D005167:Factor VII / Q000008:administration & dosage / Q000627:therapeutic use*; D015942:Factor VIIa / Q000008:administration & dosage / Q000627:therapeutic use*; D005170:Factor X / Q000008:administration & dosage / Q000627:therapeutic use*; D006330:Heart Defects, Congenital / Q000097:blood / Q000601:surgery*; D006488:Hemostasis, Surgical / Q000379:methods*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D011516:Prothrombin / Q000008:administration & dosage / Q000627:therapeutic use*; D016896:Treatment Outcome
chemical_list: D003029:Coagulants; D004338:Drug Combinations; C525441:factor IX, factor VII, factor X, prothrombin drug combination; D005167:Factor VII; D011516:Prothrombin; D005164:Factor IX; D005170:Factor X; D015942:Factor VIIa