title: Register cardiac fiber orientations from 3D DTI volume to 2D ultrasound image of rat hearts.
abstract: Two-dimensional (2D) ultrasound or echocardiography is one of the most widely used examinations for the diagnosis of cardiac diseases. However, it only supplies the geometric and structural information of the myocardium. In order to supply more detailed microstructure information of the myocardium, this paper proposes a registration method to map cardiac fiber orientations from three-dimensional (3D) magnetic resonance diffusion tensor imaging (MR-DTI) volume to the 2D ultrasound image. It utilizes a 2D/3D intensity based registration procedure including rigid, log-demons, and affine transformations to search the best similar slice from the template volume. After registration, the cardiac fiber orientations are mapped to the 2D ultrasound image via fiber relocations and reorientations. This method was validated by six images of rat heartsex vivo. The evaluation results indicated that the final Dice similarity coefficient (DSC) achieved more than 90% after geometric registrations; and the inclination angle errors (IAE) between the mapped fiber orientations and the gold standards were less than 15 degree. This method may provide a practical tool for cardiologists to examine cardiac fiber orientations on ultrasound images and have the potential to supply additional information for diagnosis of cardiac diseases.
authors: Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA.
authors: Xulei
authors: X
authors: Qin
authors: Yerkes National Primate Research Center, Emory University, Atlanta, GA.
authors: Silun
authors: S
authors: Wang
authors: Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA.
authors: Ming
authors: M
authors: Shen
authors: Yerkes National Primate Research Center, Emory University, Atlanta, GA.
authors: Xiaodong
authors: X
authors: Zhang
authors: Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA; Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA.
authors: Stamatios
authors: S
authors: Lerakis
authors: Department of Pediatrics, Emory University, Atlanta, GA.
authors: Mary B
authors: MB
authors: Wagner
authors: Department of Radiology and Imaging Sciences, Emory University, Atlanta, GA; Department of Biomedical Engineering, Emory University and Georgia Institute of Technology, Atlanta, GA.
authors: Baowei
authors: B
authors: Fei
keywords: 2D/3D registration, echocardiography; Cardiac fiber orientation; magnetic resonance diffusion tensor imaging (MR-DTI); ultrasound imaging