title: A new pretest probability score for diagnosis of lower limb deep vein thrombosis in unselected population of outpatients and inpatients.
abstract: Objective To develop a new pretest probability score for deep vein thrombosis (DVT) in unselected population of outpatients and inpatients. Methods The new score was developed using independent factors from 500 patients clinically suspected of leg DVT. The new score was validated in a second group of 315 patients. Results The score consists of four components: unilateral leg pain, confinement to bed, calf enlargement >3 cm compared with the other side, and previous venous thromboembolism. A score ≥2 indicated a high probability while a score <2 indicated low probability. The sensitivity and specificity of the new score were 71.60% and 79.49%, respectively. The area under the receiver operating characteristic curve for the new score was 0.79. The combination of a new score <2 and D-dimer level <500 µg/L had a negative predictive value of 96.43%. Conclusions Our new score was valid in an unselected population of outpatients and inpatients.
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Nuttawut
authors: N
authors: Sermsathanasawadi
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Trakarn
authors: T
authors: Chaivanit
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Pinyo
authors: P
authors: Suparatchatpun
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Khamin
authors: K
authors: Chinsakchai
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Chumpol
authors: C
authors: Wongwanit
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Chanean
authors: C
authors: Ruangsetakit
authors: Division of Vascular Surgery, Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors: Pramook
authors: P
authors: Mutirangura
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007297:Inpatients; D035002:Lower Extremity; D008297:Male; D010045:Outpatients; D011446:Prospective Studies; D020246:Venous Thrombosis / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology
keywords: D-dimer; Probability score; deep vein thrombosis; inpatients; outpatients