title: Linezolid and dexamethasone experience in a serious case of listeria rhombencephalitis.
abstract: Listeria rhombencephalitis is a rare cause of brain stem encephalitis. We report a case with a history of immunosupressive therapy due to Takayasu's arteritis that was treated with corticosteroids and linezolid for Listeria rhombencephalitis. A 63-year-old woman was admitted to the hospital with fever, headache, nausea, and vomiting. The patient's body temperature was 38°C, and she had a stiff neck. Listeria monocytogenes was isolated from the cerebrospinal fluid (CSF), and penicillin G and gentamicin treatment was initiated. Linezolid and dexamethasone were added. Due to hematuria and thrombocytopenia, the linezolid was discontinued. In immunocompromised patients with CNS infections, Listeria rhombencephalitis should be suspected. Linezolid can be used in combination with dexamethasone.
authors: Ankara Numune Education and Research Hospital, Intensive Care Clinic, Turkey.
authors: Pakize Ö
authors: PÖ
authors: Yılmaz
authors: Ankara Numune Education and Research Hospital, Intensive Care Clinic, Turkey. Electronic address: mutlunm@gmail.com.
authors: Nevzat M
authors: NM
authors: Mutlu
authors: Ankara Numune Education and Research Hospital, Infectious Diseases and Clinical Microbiology Clinic, Turkey.
authors: Ahmet
authors: A
authors: Sertçelik
authors: Ankara Numune Education and Research Hospital, Infectious Diseases and Clinical Microbiology Clinic, Turkey.
authors: Aliye
authors: A
authors: Baştuğ
authors: Ankara Numune Education and Research Hospital, Intensive Care Clinic, Turkey.
authors: Cihangir
authors: C
authors: Doğu
authors: Ankara Numune Education and Research Hospital, Infectious Diseases and Clinical Microbiology Clinic, Turkey.
authors: Sümeyye
authors: S
authors: Kışlak
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D020806:Central Nervous System Bacterial Infections / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D003907:Dexamethasone / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D000069544:Infectious Encephalitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D000069349:Linezolid / Q000627:therapeutic use*; D008089:Listeria monocytogenes; D008088:Listeriosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D008279:Magnetic Resonance Imaging; D012249:Rhombencephalon / Q000000981:diagnostic imaging
chemical_list: D000900:Anti-Bacterial Agents; D003907:Dexamethasone; D000069349:Linezolid
keywords: Dexamethasone; Linezolid; Listeria rhombencephalitis