title: Primary T-cell lymphoblastic lymphoma in the middle ear.
abstract: T-cell lymphoblastic lymphoma (T-LBL) is a highly aggressive lymphoma characterized by precursor T-cell malignancy and lymphadenopathy or mediastinal involvement. We present the case of an 11-year-old boy with a diagnosis of middle ear T-LBL, which manifested as a headache, hearing loss and peripheral facial paralysis. The child was given intensive chemotherapy and had a complete response. To our knowledge, this is the first case reported in the literature of T-LBL originating in the middle ear. This case aims to help clinicians to be vigilant about the possibility of primary lesions at atypical sites in some special diseases.
authors: Department of Otolaryngology-Head and Neck Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors: Bo
authors: B
authors: Li
authors: Department of Otolaryngology-Head and Neck Surgery, West China Hospital of Sichuan University, Chengdu, China.
authors: Shixi
authors: S
authors: Liu
authors: Department of Otolaryngology-Head and Neck Surgery, West China Hospital of Sichuan University, Chengdu, China. Electronic address: yanghui1418@163.com.
authors: Hui
authors: H
authors: Yang
authors: Department of Pathology, West China Hospital of Sichuan University, Chengdu, China.
authors: Weiya
authors: W
authors: Wang
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D002648:Child; D004428:Ear Neoplasms / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D004432:Ear, Middle / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008279:Magnetic Resonance Imaging; D008297:Male; D054218:Precursor T-Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000970:Antineoplastic Agents
keywords: Childhood; Middle ear; T-cell lymphoblastic lymphoma