title: Extensive molluscum contagiosum virus infection in a young adult receiving fingolimod.
abstract: Fingolimod-related viral infections have been described on several occasions since its introduction in 2010. We hereby add a report on an otherwise immunocompetent, 18-year old Caucasian man with relapsing-remitting multiple sclerosis who developed a protracted and extensive molluscum contagiosum (MC) virus infection shortly after being started on fingolimod. Wide-spread cutaneous MC infections in adult patients are considered indicative of underlying immunosuppression. Neurologists prescribing fingolimod ought to be aware of a possibly increased risk of MC, but also need to know about its relative benignity, lack of extra-cutaneous complications, and adequate treatment options.
authors: Department of Dermatology, Venerology and Allergology, University Hospital of Würzburg, Würzburg, Germany Behle_V@ukw.de.
authors: Valeria
authors: V
authors: Behle
authors: Department of Dermatology, Venerology and Allergology, University Hospital of Würzburg, Würzburg, Germany.
authors: Marion
authors: M
authors: Wobser
authors: Department of Dermatology, Venerology and Allergology, University Hospital of Würzburg, Würzburg, Germany.
authors: Matthias
authors: M
authors: Goebeler
authors: Department of Dermatology, Venerology and Allergology, University Hospital of Würzburg, Würzburg, Germany.
authors: Johanna
authors: J
authors: Stoevesandt
mesh_terms: D000293:Adolescent; D001706:Biopsy; D000068876:Fingolimod Hydrochloride / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D008297:Male; D008976:Molluscum Contagiosum / Q000139:chemically induced* / Q000175:diagnosis / Q000276:immunology / Q000821:virology; D008977:Molluscum contagiosum virus / Q000276:immunology*; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology; D009894:Opportunistic Infections / Q000139:chemically induced* / Q000175:diagnosis / Q000276:immunology / Q000821:virology; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents; D000068876:Fingolimod Hydrochloride
keywords: Fingolimod; immunosuppression; molluscum contagiosum; poxvirus