title: Hydrophilic GO/Fe3O4/Au/PEG nanocomposites for highly selective enrichment of glycopeptides.
abstract: GO/Fe3O4/Au/PEG nanocomposites were synthesized via bonding gold nanoparticles on magnetic graphene oxide using polyethylenimine as the reducing and immobilizing reagent, followed by thiol-terminal polyethylene glycol immobilization. With the use of this nanocomposite, 255 glycopeptides, mapped to 127 different glycoproteins, were identified from human serum, demonstrating its great potential for glycosylation analysis.
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Bo
authors: B
authors: Jiang
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Qi
authors: Q
authors: Wu
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Nan
authors: N
authors: Deng
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Yuanbo
authors: Y
authors: Chen
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Lihua
authors: L
authors: Zhang
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Zhen
authors: Z
authors: Liang
authors: National Chromatographic R. & A. Center, Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Science, Dalian 116023, China. lihuazhang@dicp.ac.cn.
authors: Yukui
authors: Y
authors: Zhang
mesh_terms: D052203:Ferrosoferric Oxide / Q000737:chemistry; D006023:Glycoproteins / Q000097:blood* / Q000737:chemistry*; D006031:Glycosylation; D006046:Gold / Q000737:chemistry; D006108:Graphite / Q000737:chemistry; D006801:Humans; D053761:Nanocomposites / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry
chemical_list: D006023:Glycoproteins; D011092:Polyethylene Glycols; D006046:Gold; D006108:Graphite; C000595209:polyethylene glycol 1000; D052203:Ferrosoferric Oxide