title: Long-Term Epidemiology of Streptococcus pneumoniae Serogroup 6 in a Region of Southern Europe with Special Reference to Serotype 6E.
abstract: Streptococcus pneumoniae serotype 6E has recently been described, but its long-term epidemiology is not well known. From 1981-2013, 704 serogroup 6 clinical isolates were obtained in Gipuzkoa, Basque Country, Spain. All invasive and one in four non-invasive isolates were included. Overall, 75, 97, 51 and 45 serotypes 6A, 6B, 6C and 6E isolates, respectively, were detected. No serotype 6D isolates were identified. The prevalence of serotypes 6E and 6B, but not that of serotypes 6A and 6C, declined after the introduction of pneumococcal conjugate vaccines. Serotype 6E isolates showed the highest resistance rate. Most serotype 6E isolates were ST90.
authors: Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain.|Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.
authors: José M
authors: JM
authors: Marimón
authors: Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.
authors: María
authors: M
authors: Ercibengoa
authors: Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.
authors: Esther
authors: E
authors: Tamayo
authors: Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain.
authors: Marta
authors: M
authors: Alonso
authors: Microbiology Department, Hospital Universitario Donostia-Instituto Biodonostia, San Sebastián, Spain.|Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián, Spain.|Faculty of Medicine, University of the Basque Country, UPV/EHU, San Sebastián, Spain.
authors: Emilio
authors: E
authors: Pérez-Trallero
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005060:Europe; D005260:Female; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D022242:Pneumococcal Vaccines; D015995:Prevalence; D012189:Retrospective Studies; D065288:Serogroup; D012703:Serotyping; D013030:Spain; D013296:Streptococcus pneumoniae / Q000145:classification*; D055815:Young Adult
chemical_list: D022242:Pneumococcal Vaccines