title: Effect of low-intensity therapeutic ultrasound on wound healing in rats subjected to third-degree burns.
abstract: OBJECTIVE
  To determine the effectiveness of low-intensity therapeutic ultrasound (LITUS) on wound healing in rats with third-degree burns.
  
  
  METHODS
  Twenty rats were divided into the Control Group that comprised four rats without third-degree burns that did not undergo LITUS, the Burned Group (BG), comprising eight rats with third-degree burns that did not undergo LITUS, and the Burned with Treatment Group (BTG), comprising eight rats with third-degree burns that were administered LITUS. LITUS began 24 h after injury and involved daily applications for 8 min at 0.1 W/cm2 for 14 days.
  
  
  RESULTS
  The BTG lost less weight than the BG (Q=2.75; p<0.05). No visible differences were apparent among the groups' lesions on day 4. By the end of treatment, wound healing was more evident in the BTG. No statistically significant differences were found between the BG and the BTG in relation to the parameters measured using the histological changes in burn wound healing scoring system.
  
  
  CONCLUSIONS
  The LITUS protocol applied to the animals with third-degree burns accelerated the formation of fibrin-leukocyte crusts and significantly reduced weight loss. However, burn wound healing was not accelerated.
authors: Universidade Federal de São Paulo, Brazil.
authors: Rayanne Lisboa
authors: RL
authors: Mesquita
authors: Universidade do Estado do Pará, Brazil.
authors: Pedro Iuri Castro da
authors: PI
authors: Silva
authors: UEPA, Belem, PA, Brazil.
authors: Simone Haru Sawaki de
authors: SH
authors: Melo e Silva
authors: Hospital Universitário João de Barros Barreto, UEPA, Belem, PA, Brazil.
authors: Kathlen Oliveira De
authors: KO
authors: Oliveira
authors: Universidade Federal do Rio de Janeiro, Brazil.
authors: Aldo José
authors: AJ
authors: Fontes-Pereira
authors: UEPA, Belem, PA, Brazil.
authors: Jofre Jacob da Silva
authors: JJ
authors: Freitas
authors: UFRJ, Rio de Janeiro, RJ, Brazil.
authors: Wagner Coelho De Albuquerque
authors: WC
authors: Pereira
authors: UEPA, Belem, PA, Brazil.
authors: Katia Simone
authors: KS
authors: Kietzer
mesh_terms: D000818:Animals; D002056:Burns / Q000145:classification / Q000473:pathology / Q000628:therapy*; D003238:Connective Tissue / Q000293:injuries*; D005337:Fibrin / Q000378:metabolism; D006358:Hot Temperature / Q000009:adverse effects; D008297:Male; D017208:Rats, Wistar; D062326:Re-Epithelialization; D000069453:Ultrasonic Waves; D015431:Weight Loss; D014945:Wound Healing
chemical_list: D005337:Fibrin