title: Classifying Germline Sequence Variants in the Era of Next-Generation Sequencing.
authors: Associate Professor of Laboratory Medicine and Pathology, Co-director, Personalized Genomics Laboratory and Clinical Genome Sequencing Laboratory, Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; baudhuin.linnea@mayo.edu.
authors: Linnea M
authors: LM
authors: Baudhuin
authors: Associate Director, Laboratory for Molecular Medicine at Partners HealthCare/Personalized Medicine, Cambridge, MA, Associate Professor of Pathology, Harvard Medical School/Massachusetts General Hospital, Boston, MA;
authors: Birgit H
authors: BH
authors: Funke
authors: Senior Director, Molecular Laboratory, Emory Genetics Laboratory, Decatur, GA;
authors: Lora H
authors: LH
authors: Bean
authors: Associate Director, UCLA Molecular Diagnostics Laboratories, Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA;
authors: Joshua L
authors: JL
authors: Deignan
authors: Director, Molecular Diagnostics and Biochemical Genetics, Division of Laboratory Medicine, Children's National Medical Center, Washington, DC;
authors: Sean
authors: S
authors: Hofherr
authors: Medical Director, Claritas Genomics, Cambridge, MA, Medical Geneticist, Division of Genetics and Genomics, Boston Children's Hospital, Associate Professor of Pediatrics, Harvard Medical School, Boston, MA;
authors: David T
authors: DT
authors: Miller
authors: Director, Integrated Genetics, Laboratory Corporation of America® Holdings, Westborough, MA;
authors: Narasimhan
authors: N
authors: Nagan
authors: Director, Division of Genomic Diagnostics, The Children's Hospital of Philadelphia, Philadelphia, PA, Assistant Professor of Clinical Pathology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;
authors: Avni
authors: A
authors: Santani
authors: Director, Molecular Genetics Laboratory, Department of Pathology and Laboratory Medicine, Children's Mercy, Kansas City, MO.
authors: Carol
authors: C
authors: Saunders
mesh_terms: D005787:Gene Frequency; D014644:Genetic Variation; D018095:Germ-Line Mutation / Q000235:genetics*; D059014:High-Throughput Nucleotide Sequencing / Q000639:trends*; D006801:Humans