title: Invasive Haemophilus influenzae Serotype f Case Reports in Mazovia Province, Poland.
abstract: After successful introduction of anti-Haemophilus influenzae (Hi) serotype b vaccination program in Poland, invasive non-b or nontypeable H. influenzae infections have been reported more frequently alike in other countries all over the world. In this paper, we report 2 cases of H. influenzae serotype f (Hif) meningitis with severe clinical presentations which are rarely seen in previously healthy children.The first case is a 6-year-old girl who was admitted to pediatric ward with signs of meningitis. Laboratory tests confirmed bacteremic meningitis caused by Hif. The girl responded very well to administered treatment and recovered without any further complications. No underlying comorbidities were found. The second patient was a 4-year-old boy who, in course of Hif bacteremic meningitis, developed rapid septicemia and, despite aggressive treatment, died within a few hours of hospitalization. The child's past history was unremarkable.By presenting these cases, we would like to remind clinicians that invasive non-b Hi infections can become fatal not only in the group of the youngest children or children with coexisting comorbidities, as most commonly reported in the worldwide literature. At the same time, we want to emphasize the legitimacy of constant monitoring Hi epidemiology in order to take accurate actions if necessary.
authors: From the Paediatric Ward, Wołomin County Hospital (AG, EK); Department of Epidemiology and Clinical Microbiology, National Reference Centre for Bacterial Meningitis, National Medicines Institute, Warsaw (AK, AS); Department of Paediatric Gastroenterology and Nutrition, Medical University of Warsaw (AG, PA, AR); and Department of Paediatric Respiratory Diseases and Allergy, Medical University of Warsaw, Warsaw, Poland (WF).
authors: Anna
authors: A
authors: Golebiewska
authors: Alicja
authors: A
authors: Kuch
authors: Agnieszka
authors: A
authors: Gawrońska
authors: Piotr
authors: P
authors: Albrecht
authors: Anna
authors: A
authors: Skoczyńska
authors: Andrzej
authors: A
authors: Radzikowski
authors: Ewa
authors: E
authors: Kutylowska
authors: Wojciech
authors: W
authors: Feleszko
mesh_terms: D002648:Child; D002675:Child, Preschool; D017809:Fatal Outcome; D005260:Female; D006192:Haemophilus Infections / Q000382:microbiology*; D006193:Haemophilus influenzae / Q000235:genetics*; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000382:microbiology*; D018805:Sepsis / Q000382:microbiology*; D065288:Serogroup