title: Carbamylated Erythropoietin: A Prospective Drug Candidate for Neuroprotection.
abstract: Carbamylated erythropoietin (cEpo), which is neuroprotective but lacks hematopoietic activity, has been attracting rising concerns. However, the cellular and molecular mechanisms involved in the process of neuroprotection of cEpo are not well known. Based on several recent reports, the neuroprotective effects of cEpo are illustrated, and signaling pathways involved in the different effects of erythropoietin and cEpo are discussed. These newly reported researches may shed new light on the development and application of cEpo, a prospective drug candidate for neuroprotection.
authors: School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
authors: Jianmin
authors: J
authors: Chen
authors: School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
authors: Zheng
authors: Z
authors: Yang
authors: School of Basic Medical Sciences, Chengdu Medical College, Chengdu, China.
authors: Xiao
authors: X
authors: Zhang
keywords: carbamylated erythropoietin; neuroprotection; signaling pathway