title: Novel Method for Neuronal Nanosurgical Connection.
abstract: Neuronal injury may cause an irreversible damage to cellular, organ and organism function. While preventing neural injury is ideal, it is not always possible. There are multiple etiologies for neuronal injury including trauma, infection, inflammation, immune mediated disorders, toxins and hereditary conditions. We describe a novel laser application, utilizing femtosecond laser pulses, in order to connect neuronal axon to neuronal soma. We were able to maintain cellular viability, and demonstrate that this technique is universal as it is applicable to multiple cell types and media.
authors: Department of Electrical and Computer Engineering, University of Alberta, Edmonton, AB, Canada.
authors: Nir
authors: N
authors: Katchinskiy
authors: Division of Pediatric Neurology, Department of Pediatrics, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
authors: Helly R
authors: HR
authors: Goez
authors: Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, AB, Canada.
authors: Indrani
authors: I
authors: Dutta
authors: Department of Oncology, University of Alberta, Cross Cancer Institute, Edmonton, AB, Canada.
authors: Roseline
authors: R
authors: Godbout
authors: Department of Electrical and Computer Engineering, University of Alberta, Edmonton, AB, Canada.
authors: Abdulhakem Y
authors: AY
authors: Elezzabi
mesh_terms: D000818:Animals; D002460:Cell Line; D002468:Cell Physiological Phenomena; D002470:Cell Survival; D007834:Lasers; D051379:Mice; D050997:Nanomedicine / Q000379:methods*; D009474:Neurons / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods*