title: CLINICAL FEATURES AND PATTERNS OF IMAGING IN CEREBRAL VENOUS SINUS THROMBOSIS AT KENYATTA NATIONAL HOSPITAL.
abstract: BACKGROUND
  Cerebral venous sinus thrombosis (CVST) is an uncommon neurological deficit. It shows a wide range of clinical manifestations that may mimic many other neurological disorders and lead to misdiagnosis. Imaging plays a key role in the diagnosis.
  
  
  OBJECTIVE
  To evaluate the clinical characteristics and patterns of neuroimaging findings in patients with radiologically confirmed CVST.
  
  
  METHODS
  A retrospective study.
  
  
  METHODS
  Kenyatta National Hospital, a tertiary referral and teaching hospital in Nairobi Kenya.
  
  
  METHODS
  Fifty one patients treated for CVST in the hospital were studied.
  
  
  RESULTS
  Fifty one patients with CVST were seen over the last five years. The median age of 30 years. The most common age group affected was 25-34 years. Females were more affected (n=38, 74.5%) than males (n=13, 25.5%). The most common presenting clinical features documented were headache, seizures and neurological deficits. Aetiological factors commonly seen included infection (n=20, 39.2%), pregnancy and puerperium (n=7, 13.7%) and oral contraceptive use (n=2, 3.9%). The most common NECT scan findings were hyperdense sinus and parenchymal changes. MRI showed loss of signal void in the sinus, gyral swelling and parenchymal signal change.
  
  
  CONCLUSIONS
  CVST is most commonly seen in young adult females due to infection, pregnancy, puerperium and oral contraceptive use. The most common clinical finding in patients with CVST is headache, followed by seizures, neck pain, neurological deficits and visual disturbance. Infective cause is much more common in our population and other developed countries compared to the developed world.
authors: Department of Diagnostic Imaging and Radiation Medicine, College of Health Sciences, University of Nairobi, PO Box 19676-00202, Nairobi, Kenya.
authors: C K
authors: CK
authors: Onyambu
authors: E
authors: E
authors: Amayo
authors: J M
authors: JM
authors: Kitonyi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007223:Infant; D007630:Kenya; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010690:Phlebography; D012189:Retrospective Studies; D012307:Risk Factors; D012851:Sinus Thrombosis, Intracranial / Q000175:diagnosis*; D014057:Tomography, X-Ray Computed; D055815:Young Adult