title: Detecting and monitoring NO, SNO and nitritein vivo.
abstract: The detection and quantification of nitric oxide and related reactive nitrogen speciesin vivois vital to the understanding of the pathology and/or treatment of numerous conditions. To that end, several detection and quantification methods have been developed to study NO, as well as its redox relatives, nitrite andS-nitrosothiols. While no single technique can offer a complete picture of the nitrogen cycle in a given systemin vivo, familiarity with the benefits and limitations of several common tools for NOxdetermination can assist in the development of new diagnostics and therapeutics.
authors: Department of Physics, Wake Forest University, 1834 Wake Forest Rd, Winston-Salem, NC 27106, USA; Department of Physical Science, The University of Findlay, 1000 N Main St, Findlay, OH 45840, USA.
authors: Landon
authors: L
authors: Bellavia
authors: Department of Physics, Wake Forest University, 1834 Wake Forest Rd, Winston-Salem, NC 27106, USA.
authors: Daniel B
authors: DB
authors: Kim-Shapiro
authors: Chemistry Department, Wake Forest University, 1834 Wake Forest Rd, Winston-Salem, NC 27106, USA.
authors: S Bruce
authors: SB
authors: King
keywords: chemiluminescence; electron paramagnetic resonance spectroscopy; spin trap