title: [THE ANALYSIS OF ASSOCIATION OF MATRIX METALLOPROTEINASE-9 AND TISSUE INHIBITOR OF METALLOPROTEINASE-1 WITH LEVEL OF ZINC IN DIFFERENT BIO SUBSTRATES IN PATIENTS WITH CAROTID STENOSIS].
abstract: The levels of matrix metalloproteinase-9 and its tissue inhibitor-1 and also zinc in serum, hair and biopsy material of atherosclerosis plaques of carotid in patients with carotid stenosis. The analysis of association between these two indicators was implemented. The highest indicators of matrix metalloproteinase-9, tissue inhibitor-I and index matrix metalloproteinase-9/tissue inhibitor-1 in patients with carotid stenosis more than 50% were established. The negative correlation between zinc concentration in serum and thickness of complex intima-media of common carotid artery was established. The weak inverse correlation of matrix metalloproteinase-9 with zinc level in atherosclerosis plaques.
authors: Z A
authors: ZA
authors: Usmanova
authors: A N
authors: AN
authors: Aripov
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D002339:Carotid Arteries / Q000473:pathology; D016893:Carotid Stenosis / Q000097:blood* / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D020780:Matrix Metalloproteinase 9 / Q000097:blood*; D008875:Middle Aged; D019715:Tissue Inhibitor of Metalloproteinase-1 / Q000097:blood*; D017539:Tunica Intima / Q000473:pathology; D015032:Zinc / Q000097:blood*
chemical_list: D015415:Biomarkers; D019715:Tissue Inhibitor of Metalloproteinase-1; C579270:MMP9 protein, human; D020780:Matrix Metalloproteinase 9; D015032:Zinc