title: Shortness of Breath and Lower Limb Edema in a 54-Year-Old Woman, Is There Any Cure?
abstract: BACKGROUND
  Pulmonary hypertension is common among patients with hyperthyroidism, and Graves' disease constitutes the most common cause of thyrotoxicosis.
  
  
  METHODS
  We report the case of a female patient admitted to the cardiology department with shortness of breath and pretibial myxedema. The diagnostic work-up revealed combined pre- and post-capillary pulmonary hypertension due to Graves' disease superimposed on left ventricular diastolic dysfunction. Restoration of thyroid function led to normalization of the pulmonary pressure and symptom resolution.
  
  
  CONCLUSIONS
  Thyroid disease is a cause of reversible pulmonary hypertension and thus should be appropriately considered in the diagnostic algorithm in patients with dyspnea, clinical signs of hyperthyroidism and elevated pulmonary pressure.
authors: Second Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece.
authors: Alexandra
authors: A
authors: Frogoudaki
authors: Second Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece.
authors: Andreas S
authors: AS
authors: Triantafyllis
authors: Second Department of Internal Medicine-Endocrine Unit, Attikon University Hospital, University of Athens, Athens, Greece.
authors: Evangeline
authors: E
authors: Vassilatou
authors: Department of Dermatology, Attikon University Hospital, University of Athens, Athens, Greece.
authors: Charalampos
authors: C
authors: Tsamakis
authors: Second Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece.
authors: Achilles
authors: A
authors: Zacharoulis
authors: Second Department of Cardiology, Attikon University Hospital, University of Athens, Athens, Greece.
authors: John
authors: J
authors: Lekakis
keywords: Dyspnea; Hypertension; Myxedema