title: Changes in Tear Film Characteristics in Patients With Idiopathic Dacryoadenitis.
abstract: OBJECTIVE
  To evaluate the tear-film meniscus with optical coherence tomography (OCT) in patients with idiopathic dacryoadenitis and to determine its relationships with the clinical tests.
  
  
  METHODS
  Sixteen patients with unilateral idiopathic dacryoadenitis were included in the study. Patients with idiopathic dacryoadenitis with affected sites (group 1), with contralateral sites (group 2) and healthy participants (group 3) completed the ocular surface disease index before optical coherence tomography determination of tear meniscus height and tear meniscus area. These were followed by measurements of tear breakup time, fluorescein staining, and Schirmer test. Finally, surgical debulking or incisional biopsies were conducted.
  
  
  RESULTS
  Tear meniscus height and tear meniscus area were the lowest in patients with affected sites (group 1) among the 3 groups (p < 0.05). Breakup time was the shortest in group 1 (p < 0.05). In the group 1, breakup time, fluorescein staining score, and histopathological phases were significantly correlated with tear meniscus height and tear meniscus area (p < 0.05).
  
  
  CONCLUSIONS
  Tear function was significantly disturbed in idiopathic dacryoadenitis. Tear menisci volumes measured by optical coherence tomography may assess the tearing function in patients with idiopathic dacryoadenitis.
authors: Department of Ophthalmology and Shanghai Key Laboratory of Visual Impairment and Restoration, Eye and ENT Hospital of Fudan University, Shanghai, China.
authors: Kang
authors: K
authors: Xue
authors: Hui
authors: H
authors: Ren
authors: Ailin
authors: A
authors: Liu
authors: Jiang
authors: J
authors: Qian
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D003607:Dacryocystitis / Q000378:metabolism / Q000503:physiopathology*; D015352:Dry Eye Syndromes / Q000378:metabolism / Q000503:physiopathology*; D005260:Female; D019793:Fluorescein / Q000378:metabolism; D005456:Fluorescent Dyes / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D013666:Tears / Q000378:metabolism / Q000502:physiology*; D041623:Tomography, Optical Coherence; D055815:Young Adult
chemical_list: D005456:Fluorescent Dyes; D019793:Fluorescein