title: [Epidemiological and clinical features of cutaneous leishmaniasis in Kairouan-Tunisia and characteristics in children].
abstract: Cutaneous leishmaniasis (CL) remains highly endemic in Tunisia. The governorate of Kairouan (Center) is one of the most affected particularly by zoonotic form due to Leishmania major. The purpose of this study was to describe the epidemiological, clinical and therapeutic features of the disease in this governorate and to identify any particularities in children. Three hundred and ninety cases were registered over 2 years (2012 and 2013). The average age was 29 years one month [± 22.7] (34.6% of patients were under 15 years). The cumulative incidence of CL was equal to 34.4 per 100,000 per year. It was higher in children (39.6 per 100,000 versus 29, p=0.004). Cases were diagnosed especially in autumn and winter (88.3% of cases between October and January, p<0.001). The average delay of consultation was one month and 22 days [± 2.5] after onset of lesions. The average number of lesions per patient was 2.7 [± 2.3] with a mean diameter equal to 2.2 cm. In addition to a higher incidence of the disease, two other features were found in "Children" group which are the presence of similar cases in the neighborhood (27.7% versus 13.4%, p=0.002) and preferential localization in the face (36.4% versus 11%) while the members were more affected in adults (63.5% versus 46.4%) (p<0.001). Meglumine antimoniate was prescribed for most of our patients (93.1%). The intramuscular route was used more than local one, probably because of high proportions of multiple lesions and facial localization.
authors: Laboratoire de recherche « Parasitoses médicales, biotechnologie et biomolécules » LR 11-IPT-06, Institut Pasteur de Tunis, Tunis, Tunisie. karim.aoun@pasteur.rns.tn.
authors: K
authors: K
authors: Chraiet-Rezgani
authors: Observatoire national des maladies nouvelles et émergentes, Tunis, Tunisie.
authors: N
authors: N
authors: Bouafif-Ben Alaya
authors: Service de pédiatrie, Hôpital Ibn Al-Jazzar, Kairouan, Tunisie.
authors: Z
authors: Z
authors: Habboul
authors: Direction régionale de la Santé, Kairouan, Tunisie.
authors: Y
authors: Y
authors: Hajjej
authors: Laboratoire de recherche « Parasitoses médicales, biotechnologie et biomolécules » LR 11-IPT-06, Institut Pasteur de Tunis, Tunis, Tunisie.
authors: K
authors: K
authors: Aoun
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D016773:Leishmaniasis, Cutaneous / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D008297:Male; D008875:Middle Aged; D012621:Seasons; D014416:Tunisia / Q000453:epidemiology; D055815:Young Adult
keywords: Child; Cutaneous leishmaniasis; Epidemiology; Kairouan; Leishmania major; Maghreb-Northern Africa; Meglumineantimoniate; Tunisia