title: Stent treatment for basilar artery dissection: A single-center experience of 21 patients.
abstract: Basilar artery dissection is a rare disease with high morbidity and mortality. No well-established management strategy exists for this lesion. Endovascular reconstructive therapy using stents (with or without coiling) may be the optimum strategy.We describe our center's experience for this treatment strategy in 21 patients with basilar artery dissection from January 2009 to July 2014 (17 men, four women; age range, 18-70 years; median age, 56 years). We divided patients into two groups: Group 1 patients received stent-assisted coiling treatment, and Group 2 patients received stent-only treatment. Pre-treatment, peri-operation and follow-up evaluation were investigated for complications, clinical outcome and angiographic results. The median follow-up time was 20 months (range, 3-67 months).All patients were treated endovascularly by stent-assisted coiling (14 patients) or stent only (seven patients). Immediate angiography showed: in Group 1, five of 14 lesions were completely occluded, five were partially occluded, four revealed retention of contrast media; in Group 2, all patients (seven of seven) had contrast retention. At the follow-up visit (median seven months, 3-29 months), the aneurysms were angiographically improved in five of 13 patients in Group 1 compared with immediately post-operation, while six of sevenimproved in Group 2. Five patients (all in Group 1) had ischemic or hemorrhage peri-operation complications. Long-term good clinical outcomes (modified Rankin Scale score (mRS) ≤ 2) were achieved in all patients except three death cases (two in Group1, one in Group 2).In our experience, endovascular reconstructive therapy using stents (with or without coiling) for basilar artery dissection is effective and safe. Stent-only treatment seems have a better safety profile during the peri-operation period.
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Li
authors: L
authors: Li
authors: Department of Intervention, People's Hospital of Zhengzhou University, China dr.litianxiao@vip.163.com.
authors: Tianxiao
authors: T
authors: Li
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Jiangyu
authors: J
authors: Xue
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Ziliang
authors: Z
authors: Wang
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Weixing
authors: W
authors: Bai
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Liangfu
authors: L
authors: Zhu
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Guang
authors: G
authors: Feng
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Gangqin
authors: G
authors: Xu
authors: Department of Intervention, People's Hospital of Zhengzhou University, China.
authors: Bowen
authors: B
authors: Yang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000784:Aortic Dissection / Q000000981:diagnostic imaging / Q000628:therapy*; D000925:Anticoagulants / Q000627:therapeutic use; D001488:Basilar Artery; D002533:Cerebral Angiography; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015607:Stents; D016896:Treatment Outcome
chemical_list: D000925:Anticoagulants
keywords: Basilar artery dissection; endovascular; stent