title: Update of the Korean Clinical Practice Guidelines for Endovascular Recanalization Therapy in Patients with Acute Ischemic Stroke.
abstract: Patients with severe stroke due to acute large cerebral artery occlusion are likely to be severely disabled or dead without timely reperfusion. Previously, intravenous tissue plasminogen activator (IV-TPA) within 4.5 hours after stroke onset was the only proven therapy, but IV-TPA alone does not sufficiently improve the outcome of patients with acute large artery occlusion. With the introduction of the advanced endovascular therapy, which enables more fast and more successful recanalization, recent randomized trials consecutively and consistently demonstrated the benefit of endovascular recanalization therapy (ERT) when added to IV-TPA. Accordingly, to update the recommendations, we assembled members of the writing committee appointed by the Korean Stroke Society, the Korean Society of Interventional Neuroradiology, and the Society of Korean Endovascular Neurosurgeons. Reviewing the evidences that have been accumulated, the writing members revised recommendations, for which formal consensus was achieved by convening a panel composed of 34 experts from the participating academic societies. The current guideline provides the evidence-based recommendations for ERT in patients with acute large cerebral artery occlusion regarding patient selection, treatment modalities, neuroimaging evaluation, and system organization.
authors: Department of Neurology, Inje University Ilsan Paik Hospital, Goyang, Korea.
authors: Keun-Sik
authors: KS
authors: Hong
authors: Department of Neurology, Seoul National University College of Medicine, Seoul, Korea.
authors: Sang-Bae
authors: SB
authors: Ko
authors: Department of Neurology, Hallym University College of Medicine, Anyang, Korea.
authors: Kyung-Ho
authors: KH
authors: Yu
authors: Department of Radiology, Seoul National University Bundang Hospital, Seongnam, Korea.
authors: Cheolkyu
authors: C
authors: Jung
authors: Department of Neurosurgery, Soonchunhyang University Seoul Hospital, Soonchunhyang University, Seoul, Korea.
authors: Sukh Que
authors: SQ
authors: Park
authors: Department of Radiology, Yonsei University College of Medicine, Seoul, Korea.
authors: Byung Moon
authors: BM
authors: Kim
authors: gDepartment of Neurosurgery, Yeungnam University School of Medicine, Daegu, Korea.
authors: Chul-Hoon
authors: CH
authors: Chang
authors: Department of Neurology, Seoul National University Bundang Hospital, Seongnam, Korea.
authors: Hee-Joon
authors: HJ
authors: Bae
authors: Department of Neurology, Yonsei University College of Medicine, Seoul, Korea.
authors: Ji Hoe
authors: JH
authors: Heo
authors: Department of Neurosurgery, Seoul National University Bundang Hospital, Seongnam, Korea.
authors: Chang Wan
authors: CW
authors: Oh
authors: Department of Neurology, Hallym University College of Medicine, Anyang, Korea.
authors: Byung-Chul
authors: BC
authors: Lee
authors: Department of Neurosurgery, Soonchunhyang University, Bucheon Hospital, Bucheon, Korea.
authors: Bum-Tae
authors: BT
authors: Kim
authors: Department of Radiology, Seoul St.Mary's Hospital, The Catholic University of Korea, Seoul, Korea.
authors: Bum-Soo
authors: BS
authors: Kim
authors: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
authors: Chin-Sang
authors: CS
authors: Chung
authors: Department of Neurology, Seoul National University College of Medicine, Seoul, Korea.
authors: Byung-Woo
authors: BW
authors: Yoon
authors: Department of Neurology, Inha University College of Medicine, Incheon, Korea.
authors: Joung-Ho
authors: JH
authors: Rha
keywords: Acute ischemic stroke; Endovascular recanalization therapy; Guidelines; Large cerebral artery occlusion; Reperfusion; Thrombolysis