title: Hidradenoma Papilliferum: A Clinicopathologic Study of 264 Tumors From 261 Patients, With Emphasis on Mammary-Type Alterations.
abstract: Hidradenoma papilliferum (HP), also known as papillary hidradenoma, is the most common benign lesion of the female anogenital area derived from anogenital mammary-like glands (AGMLG). HP can be viewed conceptually as the cutaneous counterpart of mammary intraductal papilloma. The authors have studied 264 cases of HP, detailing various changes in the tumor and adjacent AGMLG, with emphasis on mammary-type alterations. In many HP, the authors noticed changes typical for benign breast lesions, such as sclerosing adenosis-like changes, usual, and atypical ductal hyperplasia. Almost in a third of cases, remnants of AGMLG adjacent to the lesion were evident, manifesting columnar changes reminiscent of those seen in breast lesions. This study shows that the histopathological changes in HP run a broad spectrum comparable with that in the mammary counterpart and benign breast disease.
authors: *Department of Pathology, Clinical Research and Practical Center for Specialized Oncological Care, Saint-Petersburg, Russia; †Department of Pathology, Medical Faculty, Saint-Petersburg State University, Saint-Petersburg, Russia; ‡Sikl's Department of Pathology, Medical Faculty in Pilsen, Charles University in Prague, Pilsen, Czech Republic; §Bioptical Laboratory, Pilsen, Czech Republic; ¶PathWest Laboratory Medicine WA, QEII Medical Centre, Nedlands, Australia; ‖School of Pathology and Laboratory Medicine, University of Western Australia, Nedlands, Australia; **PathWest Laboratory Medicine WA, King Edward Memorial Hospital, Perth, Australia; ††Dermatopathologische Gemeinschaftspraxis, Friedrichshafen, Germany; ‡‡Clinical Department of Dermatology and Venereology, Medical University Innsbruck, Innsbruck, Austria; §§Division of Dermatopathology, Department of Pathology, Medical College of Wisconsin, Milwaukee, WI; ¶¶Dermatopathology Institute, Zürich, Switzerland; ‖‖Department of Pathology, Institute for the Care of Mother and Child, Prague, Czech Republic; ***Department of Pathology, Petrov's Research Institute of Oncology, Saint-Petersburg, Russia; †††Unit of Anatomic Pathology, School of Biomedical Sciences, Etromapmacs Pole, Lesina (FG), Italy; ‡‡‡Cytopathos Laboratory, Bratislava, Slovak Republic; §§§Agel Laboratory of Pathology, Novy Jicin, Czech Republic; and ¶¶¶Department of Dermatology, Zurich University Hospital, Zurich, Switzerland.
authors: Anastasia M
authors: AM
authors: Konstantinova
authors: Michal
authors: M
authors: Michal
authors: Denisa
authors: D
authors: Kacerovska
authors: Dominic V
authors: DV
authors: Spagnolo
authors: Colin J
authors: CJ
authors: Stewart
authors: Heinz
authors: H
authors: Kutzner
authors: Bernhard
authors: B
authors: Zelger
authors: Jose A
authors: JA
authors: Plaza
authors: Natalja
authors: N
authors: Denisjuk
authors: Vaclav
authors: V
authors: Hejda
authors: Ksenya
authors: K
authors: Shelekhova
authors: Michele
authors: M
authors: Bisceglia
authors: Dusan
authors: D
authors: Danis
authors: Michal
authors: M
authors: Zamecnik
authors: Katrin
authors: K
authors: Kerl
authors: Emmanuella
authors: E
authors: Guenova
authors: Dmitry V
authors: DV
authors: Kazakov
mesh_terms: D018250:Acrospiroma / Q000473:pathology*; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001003:Anal Canal / Q000473:pathology*; D000694:Anal Gland Neoplasms / Q000473:pathology*; D001706:Biopsy; D005260:Female; D006801:Humans; D042361:Mammary Glands, Human / Q000473:pathology*; D008875:Middle Aged; D011237:Predictive Value of Tests; D013544:Sweat Gland Neoplasms / Q000473:pathology*; D014846:Vulvar Neoplasms / Q000473:pathology*; D055815:Young Adult