title: Knowledge about Human Papillomavirus and Time to Complete Vaccination among Vulnerable Female Youth.
abstract: OBJECTIVE
  To examine the association of knowledge about human papillomavirus (HPV) on the time to completion of the 3-dose quadrivalent vaccine series in an inner-city population of adolescent female subjects at high risk for infection.
  
  
  METHODS
  We prospectively followed 139 female subjects aged 14-20 years enrolled in a vaccine surveillance study in New York City during a period of at least 24 months. Participants were given a 30-item true or false survey on HPV at enrollment and ranked according to the number of correct responses. Multivariate Cox regression was used to examine the association between level of knowledge about HPV and time to completion (in days) of vaccine dose 1-3, dose 1-2, and dose 2-3.
  
  
  RESULTS
  Overall time to completion of the 3-dose vaccine ranged from 158 days to 1114 days. Participants in the high knowledge group (top quartile) were significantly more likely to complete the 3-dose series earlier (hazard ratio 1.69, 95% CI 1.03-2.77; P = .04), in particular doses 2-3 (hazard ratio 1.71, 95% CI 1.02-2.89; P = .04), than those with low-to-moderate knowledge (bottom 3 quartiles).
  
  
  CONCLUSIONS
  These findings suggest that knowledge of HPV is associated with shorter time to complete the 3-dose HPV vaccine series. Educational campaigns at time of vaccination may be important to improve vaccine adherence.
authors: Department of Pediatrics, The Mount Sinai Medical Center, New York, NY. Electronic address: julie.nagpal@nychhc.org.
authors: Julie
authors: J
authors: Nagpal
authors: Department of Pediatrics, The Mount Sinai Medical Center, New York, NY.
authors: Lourdes Oriana
authors: LO
authors: Linares
authors: Department of Pediatrics, The Mount Sinai Medical Center, New York, NY.
authors: Jocelyn
authors: J
authors: Weiss
authors: Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY; Departments of Pediatrics, Microbiology & Immunology, and Obstetrics & Gynecology and Women's Health, Albert Einstein College of Medicine, Bronx, NY.
authors: Nicolas F
authors: NF
authors: Schlecht
authors: Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
authors: Viswanathan
authors: V
authors: Shankar
authors: Department of Pediatrics, The Mount Sinai Medical Center, New York, NY.
authors: Debra
authors: D
authors: Braun-Courville
authors: Department of Pediatrics, The Mount Sinai Medical Center, New York, NY.
authors: Anne
authors: A
authors: Nucci-Sack
authors: Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
authors: Howard D
authors: HD
authors: Strickler
authors: Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY.
authors: Robert D
authors: RD
authors: Burk
authors: Department of Pediatrics, The Mount Sinai Medical Center, New York, NY.
authors: Angela
authors: A
authors: Diaz
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D017589:Immunization Programs; D007115:Immunization Schedule; D009519:New York City; D027383:Papillomaviridae; D030361:Papillomavirus Infections / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000627:therapeutic use*; D010349:Patient Compliance; D016016:Proportional Hazards Models; D011446:Prospective Studies; D011795:Surveys and Questionnaires; D013997:Time Factors; D014505:Urban Population; D035862:Vulnerable Populations; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines