title: In vivo monitoring of local pH values in a live rat brain based on the design of a specific electroactive molecule for H(+).
abstract: pH plays an important role in the biochemical, ion-regulatory, or electrical machinery of nerve and glial cells, and is considered to be related to a number of degenerative diseases. Herein, we first develop a two-channel electrochemical ratiometric biosensor for local pH determination in a live rat brain, and report the accurate pH values in the different regions of live brains upon global cerebral ischemia.
authors: Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
authors: Fan
authors: F
authors: Zhao
authors: Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
authors: Limin
authors: L
authors: Zhang
authors: Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
authors: Anwei
authors: A
authors: Zhu
authors: Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
authors: Guoyue
authors: G
authors: Shi
authors: Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Dongchuan Road 500, Shanghai 200241, P. R. China. ytian@chem.ecnu.edu.cn.
authors: Yang
authors: Y
authors: Tian