title: Cytotoxic, genotoxic and mutagenic effects of sewage sludge on Allium cepa.
abstract: The objective of this study was to ascertain the cytotoxic, genotoxic and mutagenic potential of sewage sludge using Allium cepa bioassay. Solubilized and crude sludge from two sewage treatment stations (STSs), herein named JM and M, were tested. In addition, sanitized, crude and solubilized sludge were also analyzed from STS M. The treatments showed positive response to phytotoxicity, cytotoxicity, genotoxicity and/or mutagenicity. Despite negative results for MN F1 (micronuclei counted in F1 root cells, derived from meristematic cells), the monitoring of genotoxic and mutagenic activities of sewage sludge are recommended because in agricultural areas this residue is applied in large scale and continuously. Based on our results we advise caution in the use of sewage sludge in agricultural soils.
authors: Programa de Pós-Graduação em Genética e Melhoramento, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000, Alegre, ES, Brazil.
authors: Maria Nilza
authors: MN
authors: Corrêa Martins
authors: Departamento de Biologia, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000, Alegre, ES, Brazil.
authors: Victor Ventura
authors: VV
authors: de Souza
authors: Programa de Pós-Graduação em Genética e Melhoramento, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000, Alegre, ES, Brazil; Departamento de Biologia, Centro de Ciências Agrárias, Universidade Federal do Espírito Santo, CEP 29500-000, Alegre, ES, Brazil. Electronic address: tatianas.souza@hotmail.com.
authors: Tatiana
authors: T
authors: da Silva Souza
mesh_terms: D001681:Biological Assay; D003603:Cytotoxins / Q000633:toxicity; D004249:DNA Damage; D009152:Mutagenicity Tests; D009153:Mutagens / Q000633:toxicity; D019697:Onions / Q000187:drug effects* / Q000235:genetics; D018517:Plant Roots / Q000166:cytology; D012722:Sewage / Q000009:adverse effects*
chemical_list: D003603:Cytotoxins; D009153:Mutagens; D012722:Sewage
keywords: Biosolid; Chromosomal aberrations; Micronucleus; Sewage sludge