title: Phylogenetic Characterization Genome Segment 2 of Bluetongue Virus Strains Belonging to Serotypes 5, 7 and 24 Isolated for the First Time in China During 2012 to 2014.
abstract: Bluetongue is endemic in China, and Bluetongue virus (BTV) strains belonging to eight different serotypes (BTV-1, BTV-2, BTV-3, BTV-4, BTV-9, BTV-12, BTV-15 and BTV-16) had been isolated between 1996 and 1997. However, there has been a long pause in investigating the epidemiology of BTV infection since then. During 2012-2014, eight BTV strains belonging to serotypes 5, 7 and 24 were isolated for the first time in Yunnan and Guangdong provinces from the blood of sentinel animals. Phylogenetic analyses of genome segment 2 of these Chinese BTV strains grouped them into nucleotypes E, F and A, respectively, along with the reference strains of the same serotype. For each serotype, Chinese strains cluster together closely to form a China's sublineage. In addition, these strains were most closely related to strains from Africa, indicating that they may share a recent common ancestry with African strains. To our knowledge, this is the first time that BTV-5, BTV-7 and BTV-24 strains have been isolated in South-East Asia. These data will be beneficial for understanding the BTV epidemiology and improving diagnostic assays and control measures against bluetongue in China and its neighbouring countries in the Asia-Pacific region.
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: H
authors: H
authors: Yang
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: L
authors: L
authors: Xiao
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: J
authors: J
authors: Wang
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: J
authors: J
authors: Meng
authors: Institute of Animal Health, Guangdong Academy of Agricultural Science, Guangzhou, China.
authors: M
authors: M
authors: Lv
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: D
authors: D
authors: Liao
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: J
authors: J
authors: Song
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: L
authors: L
authors: Gao
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: H
authors: H
authors: Xiong
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: Y
authors: Y
authors: He
authors: Animal Disease Control Center of Shizong County, Shizong, China.
authors: B
authors: B
authors: Niu
authors: Animal Disease Control Center of Dehong Prefecture, Mangshi, China.
authors: X
authors: X
authors: Chuang
authors: Yunnan Tropical and Subtropical Animal Virus Diseases Laboratory, Yunnan Animal Science and Veterinary Institute, Kunming, China.
authors: H
authors: H
authors: Li
mesh_terms: D000818:Animals; D001819:Bluetongue / Q000453:epidemiology* / Q000821:virology; D001820:Bluetongue virus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D002681:China / Q000453:epidemiology; D016679:Genome, Viral; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017423:Sequence Analysis, RNA / Q000662:veterinary; D065288:Serogroup; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology* / Q000821:virology
chemical_list: D012367:RNA, Viral
keywords: Bluetongue virus; China; phylogenetic characterization; segment 2; serotype 5, 7 and 24