title: [Negative Pressure Wound Therapy with Instillation in the Treatment of Critical Wounds].
abstract: BACKGROUND
  In recent decades, negative pressure wound therapy (NPWT) has become the gold standard in the treatment of infected wounds. Negative pressure wound therapy with instillation (NPWTi) is a new development, that combines conventional NPWT with instillation of fluids.
  
  
  OBJECTIVE
  The purpose of this study was to review the results of current literature on the clinical use of NPWTi in acute and chronic wounds.
  
  
  METHODS
  A literature search was performed using Pubmed and the Cochrane Library, including articles in English and German.
  
  
  RESULTS
  The data suggest that NPWTi is a promising therapeutic option in the treatment of wounds, and applicable in various fields.
  
  
  CONCLUSIONS
  NPWTi appears to be a useful adjunct in the treatment of critical wounds. However, data from prospective randomised trials to support the validity of the results are sparse.
authors: Unfallchirurgische Klinik, Medizinische Hochschule Hannover.
authors: M
authors: M
authors: Gathen
authors: Unfallchirurgische Klinik, Medizinische Hochschule Hannover.
authors: M
authors: M
authors: Petri
authors: Unfallchirurgische Klinik, Medizinische Hochschule Hannover.
authors: C
authors: C
authors: Krettek
authors: Unfallchirurgische Klinik, Medizinische Hochschule Hannover.
authors: M
authors: M
authors: Omar
mesh_terms: D003131:Combined Modality Therapy / Q000379:methods; D003422:Critical Care / Q000379:methods*; D019317:Evidence-Based Medicine; D006801:Humans; D054843:Negative-Pressure Wound Therapy / Q000379:methods*; D012965:Sodium Chloride / Q000008:administration & dosage*; D007507:Therapeutic Irrigation / Q000379:methods*; D016896:Treatment Outcome; D014945:Wound Healing; D014946:Wound Infection / Q000628:therapy*; D014947:Wounds and Injuries / Q000628:therapy*
chemical_list: D012965:Sodium Chloride