title: Assessment of the Endoscopic Endonasal Transclival Approach for Surgical Clipping of Anterior Pontine Anterior-Inferior Cerebellar Artery Aneurysms.
abstract: OBJECTIVE
  Aneurysms of the anterior pontine segment of the anterior-inferior cerebellar artery (AICA) are uncommon. Their treatment is challenging because critical neurovascular structures are adjacent to it and the available surgical corridors are narrow and deep. Although endoscopic endonasal approaches are accepted for treating midline skull base lesions, their role in the treatment vascular lesions remains undefined. The present study is aimed to assess the anatomic feasibility of the endoscopic endonasal transclival (EET) approach for treating anterior pontine AICA aneurysms and compare it with the subtemporal anterior transpetrosal (SAT) approach.
  
  
  METHODS
  Twelve cadaveric specimens were prepared for surgical simulation. The AICAs were exposed using both EET and SAT approaches. Surgical window area and the length of the exposed artery were measured. The distance from the origin of the artery to the clip applied for proximal control was measured. The number of AICA perforators exposed and the anatomic features of each AICA were recorded.
  
  
  RESULTS
  The EET approach provided a wider surgical window area compared with the SAT (P < 0.001). More AICA perforators were visualized using the EET approach (P < 0.05). To obtain proximal control of the AICA, an aneurysm clip could be applied closer to the origin of AICA using EET (0.2 ± 0.42 mm) compared with SAT (6.26 ± 3.4 mm) (P < 0.001).
  
  
  CONCLUSIONS
  Clipping anterior pontine AICA aneurysms using the EET approach is feasible. Compared with SAT, the EET approach provides advantages in surgical window area, ensuring proximal control before aneurysm dissection, visualization of perforating branches, and better proximal control.
authors: University of California, San Francisco, California, USA.
authors: Jose L
authors: JL
authors: Sanmillan
authors: University of California, San Francisco, California, USA.
authors: Michael T
authors: MT
authors: Lawton
authors: The Johns Hopkins University, Baltimore, USA.
authors: Jordina
authors: J
authors: Rincon-Torroella
authors: University of California, San Francisco, California, USA.
authors: Ivan H
authors: IH
authors: El-Sayed
authors: University of California, San Francisco, California, USA.
authors: Xin
authors: X
authors: Zhang
authors: University of California, San Francisco, California, USA.
authors: Ali Tayebi
authors: AT
authors: Meybodi
authors: University of California, San Francisco, California, USA.
authors: Andreu
authors: A
authors: Gabarros
authors: University of California, San Francisco, California, USA. Electronic address: beneta@neurosurg.ucsf.edu.
authors: Arnau
authors: A
authors: Benet
mesh_terms: D001158:Arteries / Q000033:anatomy & histology / Q000601:surgery*; D002531:Cerebellum / Q000033:anatomy & histology / Q000098:blood supply* / Q000601:surgery; D005240:Feasibility Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000473:pathology / Q000601:surgery*; D044583:Neuroendoscopy / Q000295:instrumentation / Q000379:methods*; D011149:Pons / Q000033:anatomy & histology / Q000098:blood supply* / Q000601:surgery; D013525:Surgical Instruments
keywords: Aneurysm; Anterior inferior cerebellar artery; Anterior petrosectomy; Endoscopic endonasal approach; Intracranial aneurysm; Microsurgical clipping