title: Prevalence of blood type A and risk of vascular complications following transcatheter aortic valve implantation.
abstract: OBJECTIVE
  To assess the prevalence of blood type A among patients referred for transcatheter aortic valve implantation (TAVI) and whether it is related to vascular complications.
  
  
  BACKGROUND
  Vascular complications following TAVI are associated with adverse outcomes. Various blood types, particularly type A, have been shown to be more prevalent in cardiovascular diseases and to be related to prognosis.
  
  
  METHODS
  The prevalence of various blood types in a cohort of 491 consecutive patients who underwent TAVI was compared with a control group of 6500 consecutive hospitalised patients. The prevalence and predictors of vascular complications and bleeding events were evaluated in the blood type A group and were compared with non-type A patients.
  
  
  RESULTS
  The mean age of TAVI patients was 83 ± 6 years, and 40 % were males. Patients were divided into two groups: blood type A (n = 220) and non-type A (n = 271). Type A was significantly more prevalent in the TAVI group than in the control group (45 vs. 38 %, p = 0.023). Compared with the non-type A group, patients with blood type A had more major and fatal bleeding (14.5 vs. 8.1 %, p = 0.027) and more vascular complications (any vascular complication: 24.5 vs. 15.9 % p = 0.016; major vascular complications: 12.3 vs. 7 % p = 0.047). In a multivariable analysis, blood type A emerged as a significant and independent predictor for vascular complications and bleeding events.
  
  
  CONCLUSIONS
  Blood type A is significantly more prevalent in TAVI patients than in the general population and is related to higher rates of vascular and bleeding complications.
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: M-T
authors: MT
authors: Rofe
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: Y
authors: Y
authors: Shacham
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: A
authors: A
authors: Steinvi
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: L
authors: L
authors: Barak
authors: Department of Haematology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors: M
authors: M
authors: Hareuveni
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: S
authors: S
authors: Banai
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: G
authors: G
authors: Keren
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel.
authors: A
authors: A
authors: Finkelstein
authors: Department of Cardiology, Tel Aviv Sourasky Medical Center, Affiliated to the Sackler Faculty of Medicine, Tel Aviv, Israel. haim.shmilovich@gmail.com.
authors: H
authors: H
authors: Shmilovich
keywords: Aortic stenosis; Blood type A; Transcatheter aortic valve implantation; Vascular complications