title: [Value of the Geriatric Nutritional Risk Index in predicting mortality of elderly patients undergoing hemodialysis].
abstract: OBJECTIVE
  To explore the reliability of the Geriatric Nutritional Risk Index (GNRI) as a mortality predictor in elderly patients undergoing hemodialysis (HD).
  
  
  METHODS
  A total of 125 maintenance HD patients aged >60 years old who had received dialysis for over 6 months before entry was retrospectively examined. The values of GNRI were calculated, and death was taken as the end point. The patients were divided into 4 groups according to the quartiles of GNRI values. All-cause and cardiovascular mortality were calculated using Kaplan-Meier and cox proportional-hazards analyses, and ROC curve was adopted for analyzing the predicting value of GNRI on mortality.
  
  
  RESULTS
  The GNRI of the four groups were ≤92.06, 92.07-96.15, 96.16-101.25, ≥101.26, respectively. Kaplan-Meier survival rate was significantly different among 4 groups for all-cause and cardiovascular mortality. Cox regression model analysis demonstrated that the GNRI was a predictor for all cause (HR=0.940, P=0.001, 95%CI: 0.907-0.974) and cardiovascular mortality (HR=0.906, P<0.001, 95%CI: 0.863-0.951). The area under ROC curve was 0.667 (P=0.001) for all-cause mortality and 0.717 (P=0.001) for cardiovascular mortality.
  
  
  CONCLUSIONS
  The GNRI is a reliable predictor for all-cause mortality in maintainance HD patients, but more multi-center studies with larger samples are still needed.
authors: Department of Nephrology, Shanghai Jiaotong University, Shanghai First People's Hospital , Shanghai 200080, China.
authors: Yuran
authors: Y
authors: Zhang
authors: Department of Nephrology, Shanghai Jiaotong University, Shanghai First People's Hospital , Shanghai 200080, China.
authors: Zheng
authors: Z
authors: Zhang
authors: Department of Nephrology, Shanghai Jiaotong University, Shanghai First People's Hospital , Shanghai 200080, China.
authors: Qing
authors: Q
authors: Yu
authors: Department of Nephrology, Shanghai Jiaotong University, Shanghai First People's Hospital , Shanghai 200080, China; Email: ywj4169@163.com.
authors: Weijie
authors: W
authors: Yuan
mesh_terms: D000368:Aged; D006801:Humans; D009752:Nutritional Status; D012372:ROC Curve; D006435:Renal Dialysis; D015203:Reproducibility of Results; D012189:Retrospective Studies; D015996:Survival Rate