title: A Review of Casein Phosphopeptide-Amorphous Calcium Phosphate (CPP-ACP) and Enamel Remineralization.
abstract: White-spot lesions are the earliest macroscopic evidence of enamel caries. In such a situation, the enamel surface layer stays intact during subsurface demineralization, but without treatment the subsurface loss will continue, and eventually the surface layer will collapse and lead to a cavity formation. By introducing casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) at this stage the lesion can be reversed. CPP-ACP is a unique, naturally derived protein-based remineralizing technology that is now used globally in chewing gums and topical creams. The aim of this review is to expound on the potential for reversal of demineralization through the use of products such as CPP-ACP, and to provide guidance to clinicians considering remineralization as a viable treatment option.
authors: PG First Year, Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Haryana, India.
authors: Neetu
authors: N
authors: Gupta
authors: Professor and Department Head, Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Haryana, India.
authors: Charu
authors: C
authors: Mohan Marya
authors: Reader, Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Haryana, India.
authors: Ruchi
authors: R
authors: Nagpal
authors: Reader, Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Haryana, India.
authors: Sukhvinder
authors: S
authors: Singh Oberoi
authors: Senior Lecturer, Department of Public Health Dentistry, Sudha Rustagi College of Dental Sciences and Research, Haryana, India.
authors: Chandan
authors: C
authors: Dhingra
mesh_terms: D002327:Cariostatic Agents; D002364:Caseins / Q000627:therapeutic use*; D003743:Dental Enamel; D006801:Humans; D010748:Phosphopeptides; D014089:Tooth Remineralization
chemical_list: D002327:Cariostatic Agents; D002364:Caseins; D010748:Phosphopeptides; C447032:casein phosphopeptide-amorphous calcium phosphate nanocomplex