title: Flaxseed flour, compared to flaxseed oil, contributes to femoral structure in male rats subjected to early weaning.
abstract: The aim of this study was to analyze whether flaxseed flour or flaxseed oil treatment contributes to femoral structure in male rats subjected to early weaning. Pups were weaned for separation from mothers at 14 days (early weaning, EW) or 21 days (control, C). After 21 days, the control (C60) was fed with the control diet. The EW group was divided based on control (EWC60), flaxseed flour (EWFF60) and flaxseed oil (EWFO60) diets until 60 days. Femoral dimension, bone mineral density (BMD), bone mineral content (BMC), area and biomechanical properties were determined. EWFO60 showed lower (P < 0.05) femur mass. EWC60 and EWFO60 showed lower (P < 0.05) distance between epiphyses, diaphysis width and BMD. BMC was lower (P < 0.05) in EWC60 (vs. C60 and EWFF60). EWC60 and EWFO60 showed lower (P < 0.05) maximum force (vs. C60). Breaking strength was lower (P < 0.05) in EWFO60 (vs. C60). EWFF60 showed higher (P < 0.05) rigidity. Flaxseed flour abbreviated the femoral fragility secondary to early weaning.
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Carolina Ribeiro
authors: CR
authors: Pessanha
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Bianca Ferolla
authors: BF
authors: da Camara Boueri
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Luanna Rodrigues
authors: LR
authors: da Costa
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Maitê Rocha
authors: MR
authors: Ferreira
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Maíra Duque Coutinho
authors: MD
authors: de Abreu
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Letícia Rozeno
authors: LR
authors: Pessoa
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Aline D'Avila
authors: AD
authors: Pereira
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Danielle Cavalcante
authors: DC
authors: Ribeiro
authors: Analytical Laboratory of Restorative Biomaterials, Dental School, Fluminense Federal University, Niterói, RJ, Brazil.
authors: Eduardo Moreira
authors: EM
authors: da Silva
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Carlos Alberto Soares
authors: CA
authors: da Costa
authors: Laboratory of Experimental Nutrition, Department of Nutrition and Dietetics, Fluminense Federal University, Niterói, RJ, Brazil. nutcarlos@hotmail.com.
authors: Gilson Teles
authors: GT
authors: Boaventura
mesh_terms: D000818:Animals; D015519:Bone Density; D005260:Female; D005269:Femur / Q000737:chemistry / Q000502:physiology*; D019597:Flax / Q000737:chemistry / Q000378:metabolism*; D005433:Flour / Q000032:analysis; D008043:Linseed Oil / Q000032:analysis / Q000378:metabolism*; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D014886:Weaning
chemical_list: D008043:Linseed Oil