title: Corneal fibrosarcoma in a cat.
abstract: OBJECTIVE
  To present the clinicopathologic features of a Domestic Short-haired cat with spontaneous, intermediate-grade corneal fibrosarcoma, possibly secondary to chronic corneal irritation associated with a corneal sequestrum.
  
  
  METHODS
  A 12-year-old, spayed female Domestic Short-haired cat was evaluated for a slowly growing, pink, exophytic mass affecting the left cornea. The cat had presented 6 years previously for bilateral brown corneal sequestra, as well as 3 years previously for a small pale growth on the left cornea hypothesized to be an epithelial inclusion cyst and a corneal ulcer affecting the right eye. Incisional biopsy of the corneal mass indicated intermediate-grade corneal fibrosarcoma within the corneal stroma. Owing to the potential for malignant behavior, the left globe was enucleated. Routine systemic staging was performed prior to surgery with no evidence of metastasis.
  
  
  RESULTS
  Definitive diagnosis of corneal fibrosarcoma was made through histopathologic examination of the incisional biopsy. There was an elevated mitotic index, indicating an intermediate-grade phenotype. Histopathology of the enucleated globe substantiated the initial findings, and complete tumor resection was confirmed. Subjacent to the corneal fibrosarcoma, there was a region of necrotic tissue suggestive of a corneal sequestrum. Six months after diagnosis and enucleation, the patient remained healthy with no signs of local spread or distant metastasis.
  
  
  CONCLUSIONS
  To the authors' knowledge, this is the first documented case of a corneal fibrosarcoma in a cat.
authors: Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, 1600 S. 16th St, Ames, IA, 50011, USA.
authors: Travis D
authors: TD
authors: Strong
authors: Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, 1600 S. 16th St, Ames, IA, 50011, USA.
authors: Sarah
authors: S
authors: Tangeman
authors: Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, 1600 S. 16th St, Ames, IA, 50011, USA.
authors: Gil
authors: G
authors: Ben-Shlomo
authors: Department of Veterinary Pathology, Iowa State University College of Veterinary Medicine, 1600 S. 16th St, Ames, IA, 50011, USA.
authors: Joseph
authors: J
authors: Haynes
authors: Department of Veterinary Clinical Sciences, Iowa State University College of Veterinary Medicine, 1600 S. 16th St, Ames, IA, 50011, USA.
authors: Rachel A
authors: RA
authors: Allbaugh
keywords: cat; cornea; fibrosarcoma; inflammation; sequestrum; ulcer