title: Detection of carbapenemase-producing gram-negative bacteria using a simplified Carba NP test.
abstract: A simplified Carba NP test (CNPt), the CNPt-direct, was evaluated for carbapenemase detection using 272 gram-negative bacteria. Compared to the Modified Hodge test, the CNPt-direct had higher sensitivity (98.2% vs. 71.6%). The simplified Carba NP is an accurate, cheap and simple test for rapid carbapenemase detection.
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China.
authors: Qun
authors: Q
authors: Yan
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China.
authors: Qingxia
authors: Q
authors: Liu
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China.
authors: Yanming
authors: Y
authors: Li
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China.
authors: Hongling
authors: H
authors: Li
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China.
authors: Xianghui
authors: X
authors: Liang
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China.
authors: Mingxiang
authors: M
authors: Zou
authors: Department of Clinical Laboratory, Xiangya Hospital of Central South University, Changsha, Hunan, China. Electronic address: wenenliu@163.com.
authors: Wen-En
authors: WE
authors: Liu
mesh_terms: D001426:Bacterial Proteins / Q000032:analysis* / Q000378:metabolism; D001431:Bacteriological Techniques / Q000379:methods*; D057075:Enzyme Assays / Q000379:methods*; D006090:Gram-Negative Bacteria / Q000201:enzymology / Q000302:isolation & purification; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis / Q000382:microbiology*; D006801:Humans; D001618:beta-Lactamases / Q000032:analysis / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D001618:beta-Lactamases; C063912:carbapenemase
keywords: CNPt-direct; Carba NP test; Carbapenemase