title: Fluoridated hydroxyapatite: Eu(3+) nanorods-loaded folate-conjugated D-α-tocopheryl polyethylene glycol succinate (vitamin E TPGS) micelles for targeted imaging of cancer cells.
abstract: In this study, fluoridated hydroxyapatite: Eu(3+) nanorod-loaded folate-conjugated TPGS micelles were prepared by thin-film hydration. The findings in this study demonstrate that micelles show improved dispersion, high stability, and excellent fluorescent property in aqueous solutions, suitable for targeted imaging of cancer cells with over-expressing folate receptors on their surface. The micelles designed in this study will be a promising tool for early detection of cancer.
authors: School of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin 300387, People's Republic of China.
authors: Dong
authors: D
authors: Wan
authors: Weijiao
authors: W
authors: Liu
authors: Lei
authors: L
authors: Wang
authors: Hao
authors: H
authors: Wang
authors: Jie
authors: J
authors: Pan
mesh_terms: D002470:Cell Survival; D003952:Diagnostic Imaging; D004355:Drug Stability; D005492:Folic Acid / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D006882:Hydroxyapatites / Q000737:chemistry*; D061986:MCF-7 Cells; D008823:Micelles; D058726:Nanoconjugates / Q000737:chemistry / Q000648:ultrastructure; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology*; D011092:Polyethylene Glycols / Q000737:chemistry; D014810:Vitamin E / Q000031:analogs & derivatives* / Q000737:chemistry
chemical_list: D006882:Hydroxyapatites; D008823:Micelles; D058726:Nanoconjugates; D014810:Vitamin E; D011092:Polyethylene Glycols; C028869:fluor-hydroxylapatite; D005492:Folic Acid; C014225:tocophersolan