title: Frequency and clinical correlates of postural and striatal deformities in Parkinson's disease.
abstract: OBJECTIVE
  To assess the frequency of postural and striatal deformities in patients with Parkinson's disease.
  
  
  METHODS
  A total of 416 consecutive patients with Parkinson's disease were evaluated for musculoskeletal deformities using a standardized criteria. Data including disease history, motor complications and antiparkinsonic treatment were collected.
  
  
  RESULTS
  The overall frequency of musculoskeletal deformities was 19.7%. Striatal deformities were the most frequent deformities (9.9%). Scoliosis was the deformity most frequently found. No cases with Pisa syndrome or antecollis were found. Striatal deformities were associated with a younger age at onset, more frequent use of levodopa, as well as higher levodopa equivalent daily dose. Postural deformities were associated with higher motor scores.
  
  
  CONCLUSIONS
  Postural and striatal deformities are common in Parkinson's disease. Striatal deformities appear to be more related to dopaminergic treatment, while postural deformities are associated with the motor state.
authors: Clinical Neurodegenerative Research Unit, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
authors: Amin
authors: A
authors: Cervantes-Arriaga
authors: Clinical Neurodegenerative Research Unit, National Institute of Neurology and Neurosurgery, Mexico City, Mexico; Movement Disorder Clinic, National Institute of Neurology and Neurosurgery, Mexico City, Mexico. Electronic address: mayelarv@gmail.com.
authors: Mayela
authors: M
authors: Rodríguez-Violante
authors: Department of Neurology, Centro Médico Nacional Siglo XXI, Mexico City, Mexico.
authors: Hugo
authors: H
authors: Morales-Briceño
authors: Department of Neurology, Centro Médico Nacional Siglo XXI, Mexico City, Mexico.
authors: Gabriel
authors: G
authors: Neri-Nani
authors: Department of Neurology, General Hospital, Zacatecas, Mexico.
authors: Roxanna
authors: R
authors: Millán-Cepeda
authors: Clinical Neurodegenerative Research Unit, National Institute of Neurology and Neurosurgery, Mexico City, Mexico.
authors: Salvador
authors: S
authors: Velázquez-Osuna
mesh_terms: D000328:Adult; D017668:Age of Onset; D000368:Aged; D003342:Corpus Striatum / Q000187:drug effects / Q000503:physiopathology*; D005260:Female; D006225:Hand / Q000503:physiopathology; D006801:Humans; D007980:Levodopa / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010300:Parkinson Disease / Q000188:drug therapy / Q000503:physiopathology*; D011187:Posture / Q000502:physiology*
chemical_list: D007980:Levodopa
keywords: Parkinson’s disease; Postural deformities; Striatal foot; Striatal hand