title: Cobalt-Catalyzed Bis-alkynylation of Amides via Double C-H Bond Activation.
abstract: The first example of cobalt-catalyzed selective bis-alkynylation of amides via double C-H bond activation with the directing assistance of a removable bidentate auxiliary is reported. The developed alkynylation strategy is simple, efficient, and tolerant of various functional groups including ether, amine, halides, and heterocyclic motifs. The reaction can be scaled up under mild conditions.
authors: Catalysis Division, Dr. Homi Bhabha Road, CSIR-National Chemical Laboratory (CSIR-NCL) , Pune - 411008, India.|Academy of Scientific and Innovative Research (AcSIR), New Delhi - 110 025, India.
authors: Vinod G
authors: VG
authors: Landge
authors: Catalysis Division, Dr. Homi Bhabha Road, CSIR-National Chemical Laboratory (CSIR-NCL) , Pune - 411008, India.|Academy of Scientific and Innovative Research (AcSIR), New Delhi - 110 025, India.
authors: Garima
authors: G
authors: Jaiswal
authors: Catalysis Division, Dr. Homi Bhabha Road, CSIR-National Chemical Laboratory (CSIR-NCL) , Pune - 411008, India.|Academy of Scientific and Innovative Research (AcSIR), New Delhi - 110 025, India.
authors: Ekambaram
authors: E
authors: Balaraman