title: Bioinformatics Analysis of NBS-LRR Encoding Resistance Genes in Setaria italica.
abstract: In plants, resistance (R) genes are involved in pathogen recognition and subsequent activation of innate immune responses. The nucleotide-binding site-leucine-rich repeat (NBS-LRR) genes family forms the largest R-gene family among plant genomes and play an important role in plant disease resistance. In this paper, comprehensive analysis of NBS-encoding genes is performed in the whole Setaria italica genome. A total of 96 NBS-LRR genes are identified, and comprehensive overview of the NBS-LRR genes is undertaken, including phylogenetic analysis, chromosome locations, conserved motifs of proteins, and gene expression. Based on the domain, these genes are divided into two groups and distributed in all Setaria italica chromosomes. Most NBS-LRR genes are located at the distal tip of the long arms of the chromosomes. Setaria italica NBS-LRR proteins share at least one nucleotide-biding domain and one leucine-rich repeat domain. Our results also show the duplication of NBS-LRR genes in Setaria italica is related to their gene structure.
authors: College of Agriculture and Forestry, Hebei North University, Zhangjiakou, 075000, China.
authors: Yan
authors: Y
authors: Zhao
authors: College of Agriculture and Forestry, Hebei North University, Zhangjiakou, 075000, China.
authors: Qiaoyun
authors: Q
authors: Weng
authors: College of Agriculture and Forestry, Hebei North University, Zhangjiakou, 075000, China.
authors: Jinhui
authors: J
authors: Song
authors: College of Agriculture and Forestry, Hebei North University, Zhangjiakou, 075000, China.
authors: Hailian
authors: H
authors: Ma
authors: College of Agriculture and Forestry, Hebei North University, Zhangjiakou, 075000, China.
authors: Jincheng
authors: J
authors: Yuan
authors: Hebei Academy of Agriculture and Forestry Sciences, National Foxtail Millet Improvement Center, Minor Cereal Crops Laboratory of Hebei Province, Shijiazhuang, China.
authors: Zhiping
authors: Z
authors: Dong
authors: College of Agriculture and Forestry, Hebei North University, Zhangjiakou, 075000, China. leely519@126.com.
authors: Yinghui
authors: Y
authors: Liu
mesh_terms: D002874:Chromosome Mapping; D019295:Computational Biology / Q000379:methods*; D060467:Disease Resistance; D018506:Gene Expression Regulation, Plant; D000090263:Leucine-Rich Repeat Proteins; D005810:Multigene Family; D010802:Phylogeny; D010935:Plant Diseases / Q000235:genetics; D010940:Plant Proteins / Q000235:genetics; D000072417:Protein Domains; D011506:Proteins / Q000737:chemistry / Q000235:genetics*; D032983:Setaria Plant / Q000235:genetics*
chemical_list: D000090263:Leucine-Rich Repeat Proteins; D010940:Plant Proteins; D011506:Proteins
keywords: Bioinformatics analysis; Distribution; LRR; Motif; NBS