title: Approach to Isoindolinones, Isoquinolinones, and THIQs via Lewis Acid-Catalyzed Domino Strecker-Lactamization/Alkylations.
abstract: A one-pot, three-component synthesis of widely substituted isoindolinones and isoquinolinones, featuring a Lewis acid-catalyzed efficient Strecker reaction and lactamization sequence, affording products in good to high yields is reported. The method has also been extended to the synthesis of tetrahydroisoquinolines (THIQs) in high yields.
authors: Department of Chemistry, Indian Institute of Technology , Kanpur, UP - 208 016, India.
authors: Sivasankaran
authors: S
authors: Dhanasekaran
authors: Department of Chemistry, Indian Institute of Science Education and Research , Bhopal, MP - 462 066, India.
authors: Arun
authors: A
authors: Suneja
authors: Department of Chemistry, Indian Institute of Science Education and Research , Bhopal, MP - 462 066, India.
authors: Vishnumaya
authors: V
authors: Bisai
authors: Department of Chemistry, Indian Institute of Science Education and Research , Bhopal, MP - 462 066, India.|Department of Chemistry, Indian Institute of Technology , Kanpur, UP - 208 016, India.
authors: Vinod K
authors: VK
authors: Singh