title: 68Ga-Labeled Anti-Prostate-Specific Membrane Antigen Peptide as Marker for Androgen Deprivation Therapy Response in Prostate Cancer.
abstract: Prostate cancer was diagnosed in a 71-year-old man with an elevated prostate-specific antigen. The CT of the abdomen showed multiple para-aortal lymph nodes, and thus, a Ga anti-prostate-specific membrane antigen (PSMA-11) PET/CT was initiated, which showed, aside from the prostate cancer and multiple iliacal and para-aortal lymph node metastases, an increased tracer uptake in a lymph node left cervical. According to this advanced disease, a palliative therapy with GnRH agonist was initiated. A second PSMA-11 PET/CT was performed 4 months later, which showed a very good response; thus, additional radiation of the pelvis and the draining lymphatic system was performed.
authors: From the Departments of *Nuclear Medicine, and †Urology, University Hospital Bonn, Bonn, Germany.
authors: Carl Diedrich
authors: CD
authors: Schlenkhoff
authors: Florian
authors: F
authors: Gaertner
authors: Markus
authors: M
authors: Essler
authors: Stefan
authors: S
authors: Hauser
authors: Hojjat
authors: H
authors: Ahmadzadehfar
mesh_terms: D000368:Aged; D000726:Androgen Antagonists / Q000627:therapeutic use*; D000954:Antigens, Surface / Q000378:metabolism*; D014408:Biomarkers, Tumor / Q000378:metabolism*; D005710:Gallium Radioisotopes; D043425:Glutamate Carboxypeptidase II / Q000378:metabolism*; D007987:Gonadotropin-Releasing Hormone / Q000819:agonists; D006801:Humans; D008297:Male; D049268:Positron-Emission Tomography / Q000379:methods; D017430:Prostate-Specific Antigen / Q000378:metabolism*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D000726:Androgen Antagonists; D000954:Antigens, Surface; D014408:Biomarkers, Tumor; D005710:Gallium Radioisotopes; D007987:Gonadotropin-Releasing Hormone; C473848:FOLH1 protein, human; D043425:Glutamate Carboxypeptidase II; D017430:Prostate-Specific Antigen