title: Lipid Nanotube Tailored Fabrication of Uniquely Shaped Polydopamine Nanofibers as Photothermal Converters.
abstract: Helically coiled and linear polydopamine (PDA) nanofibers were selectively fabricated with two different types of lipid nanotubes (LNTs) that acted as templates. The obtained coiled PDA-LNT hybrid showed morphological advantages such as higher light absorbance and photothermal conversion effect compared to a linear counterpart. Laser irradiation of the coiled PDA-LNT hybrid induced a morphological change and subsequent release of the encapsulated guest molecule. In cellular experiments, the coiled PDA-LNT efficiently eliminated HeLa cells because of its strong affinity with the tumor cells. This work illustrates the first approach to construct characteristic morphologies of PDA nanofibers using LNTs as simple templates, and the coiled PDA-LNT hybrid exhibits attractive photothermal features derived from its unique coiled shape.
authors: Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan. ding-wuxiao@aist.go.jp.
authors: Wuxiao
authors: W
authors: Ding
authors: Nanomaterials Research Institute, AIST, Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
authors: Svetlana A
authors: SA
authors: Chechetka
authors: Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
authors: Mitsutoshi
authors: M
authors: Masuda
authors: National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
authors: Toshimi
authors: T
authors: Shimizu
authors: Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
authors: Masaru
authors: M
authors: Aoyagi
authors: Research Institute for Sustainable Chemistry, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan.
authors: Hiroyuki
authors: H
authors: Minamikawa
authors: Nanomaterials Research Institute, AIST, Tsukuba Central 5, 1-1-1 Higashi, Tsukuba, Ibaraki, 305-8565, Japan. e-miyako@aist.go.jp.
authors: Eijiro
authors: E
authors: Miyako
mesh_terms: D006367:HeLa Cells; D006801:Humans; D007211:Indoles / Q000737:chemistry*; D008055:Lipids / Q000737:chemistry*; D057139:Nanofibers / Q000737:chemistry*; D043942:Nanotubes / Q000737:chemistry*; D055668:Photochemical Processes; D011108:Polymers / Q000737:chemistry*
chemical_list: D007211:Indoles; D008055:Lipids; D011108:Polymers; C568283:polydopamine
keywords: morphology effect; nanotube; photothermal; polydopamine; template synthesis