title: Imparting Nonfouling Properties to Chemically Distinct Surfaces with a Single Adsorbing Polymer: A Multimodal Binding Approach.
abstract: Surface-active polymers that display nonfouling properties and carry binding groups that can adsorb onto different substrates are highly desirable. We present a postmodification protocol of an active-ester-containing polymer that allows the creation of such a versatile platform. Poly(pentafluorophenyl acrylate) has been postmodified with a fixed grafting ratio of a nonfouling function (mPEG) and various combinations of functional groups, such as amine, silane and catechol, which can provide strong affinity to two model substrates: SiO2 and TiO2 . Adsorption, stability and resistance to nonspecific protein adsorption of the polymer films were studied. A polymer was obtained that maintained its surface functionality under a variety of harsh conditions. EG surface-density calculations show that this strategy generates a denser packing when both negatively and positively charged groups are present within the backbone, and readily allows the fabrication of a broad combinatorial matrix.
authors: SuSoS AG, Lagerstrasse 14, CH-8600, Dübendorf, Switzerland.|Laboratory for Surface Science and Technology, Department of Materials, ETH Zürich, Vladimir-Prelog-Weg 5, CH-8093, Zürich, Switzerland.
authors: Ângela
authors: Â
authors: Serrano
authors: SuSoS AG, Lagerstrasse 14, CH-8600, Dübendorf, Switzerland.|Laboratory for Surface Science and Technology, Department of Materials, ETH Zürich, Vladimir-Prelog-Weg 5, CH-8093, Zürich, Switzerland.
authors: Stefan
authors: S
authors: Zürcher
authors: SuSoS AG, Lagerstrasse 14, CH-8600, Dübendorf, Switzerland.|Laboratory for Surface Science and Technology, Department of Materials, ETH Zürich, Vladimir-Prelog-Weg 5, CH-8093, Zürich, Switzerland.
authors: Samuele
authors: S
authors: Tosatti
authors: Laboratory for Surface Science and Technology, Department of Materials, ETH Zürich, Vladimir-Prelog-Weg 5, CH-8093, Zürich, Switzerland.
authors: Nicholas D
authors: ND
authors: Spencer
mesh_terms: D000327:Adsorption; D002396:Catechols / Q000737:chemistry; D011092:Polyethylene Glycols / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry; D014025:Titanium / Q000737:chemistry
chemical_list: D002396:Catechols; D011108:Polymers; D013501:Surface-Active Agents; C009495:titanium dioxide; D011092:Polyethylene Glycols; D012822:Silicon Dioxide; D014025:Titanium; C034221:catechol
keywords: functional coatings; self-assembled monolayers; surface functionalization; ultrathin films