title: A case series of dural venous sinus stenting in idiopathic intracranial hypertension: association of outcomes with optical coherence tomography.
abstract: Purpose/Aim: Pseudotumor cerebri or idiopathic intracranial hypertension (IIH) is characterized by increased intracranial pressure of unknown etiology. A subset of patients has shown benefit from endovascular dural venous sinus stenting (DVSS). We sought to identify a population of IIH patients who underwent DVSS to assess outcomes.
  
  
  METHODS
  A retrospective study was performed to identify IIH patients with dural sinus stenosis treated with DVSS. Outcome measures included dural sinus pressure gradients, peripapillary retinal nerve fiber layer (RNFL) thickness using optical coherence tomography and improvement in symptoms.
  
  
  RESULTS
  Seventeen patients underwent DVSS. Average pre- and post-intervention pressure gradients were 23.06 and 1.18 mmHg, respectively (p < 0.0001). Sixteen (94%) noted improvement in headache, fourteen (82%) had visual improvement and all (100%) patients had improved main symptom. Of 11 patients with optical coherence tomography, 8 showed decreased RNFL thickness and 3 remained stable; furthermore, these 11 patients had improved vision with improved papilledema in 8, lack of pre-existing papilledema in 2 and stable, mild edema in 1 patient.
  
  
  CONCLUSIONS
  Our series of patients with dural sinus stenosis demonstrated improvement in vision and reduction in RNFL thickness. DVSS appears to be a useful treatment for IIH patients with dural sinus stenosis.
authors: a Department of Neurosurgery.
authors: Kyle A
authors: KA
authors: Smith
authors: a Department of Neurosurgery.
authors: Jeremy C
authors: JC
authors: Peterson
authors: a Department of Neurosurgery.
authors: Paul M
authors: PM
authors: Arnold
authors: a Department of Neurosurgery.
authors: Paul J
authors: PJ
authors: Camarata
authors: b Department of Ophthalmology.
authors: Thomas J
authors: TJ
authors: Whittaker
authors: c Department of Interventional Radiology.|d Department of Neurology , University of Kansas Medical Center , Kansas City , KS , USA.
authors: Michael G
authors: MG
authors: Abraham
mesh_terms: D000086:Acetazolamide / Q000627:therapeutic use; D000328:Adult; D000927:Anticonvulsants / Q000627:therapeutic use; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000209:etiology; D006801:Humans; D008297:Male; D017063:Outcome Assessment, Health Care; D010690:Phlebography; D011559:Pseudotumor Cerebri / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy*; D012189:Retrospective Studies; D015607:Stents; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
chemical_list: D000927:Anticonvulsants; D000086:Acetazolamide
keywords: idiopathic intracranial hypertension; neuro-ophthalmology; pseudotumor; retina; venous stent