title: Metabolically Active Brown Fat Mimicking Pericardial Metastasis on PET/CT: The Discriminating Role of Cardiac Magnetic Resonance Imaging.
abstract: Metabolically active mediastinal brown adipose tissue may be mistakenly diagnosed as a malignancy on 18F-fluoro-2-deoxy-D-glucose (FDG)/positron emission tomography (PET). We report the case of a patient with locally recurrent breast carcinoma in which staging PET/CT revealed a suspicious pericardial lesion for which the patient was referred to our centre. The novelty of this case resides in the fact that by tissue characterization, cardiac magnetic resonance imaging allowed the determination that the lesion corresponded to brown fat, a reassuring finding with important impact on management, because the presence of pericardial metastasis would have disqualified this patient for curative resection of her cancer recurrence.
authors: Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom; Department of Cardiology, Hôpital du Sacré-Coeur de Montréal, Montréal, Québec, Canada.
authors: Maude
authors: M
authors: Pagé
authors: Department of Cardiac Surgery, Royal Brompton Hospital, London, United Kingdom.
authors: Cesare
authors: C
authors: Quarto
authors: Department of Cardiac Surgery, Royal Brompton Hospital, London, United Kingdom.
authors: Enrico
authors: E
authors: Mancuso
authors: Cardiovascular Magnetic Resonance Unit, Royal Brompton Hospital, London, United Kingdom; National Heart and Lung Institute, Imperial College London, United Kingdom. Electronic address: r.mohiaddin@rbht.nhs.uk.
authors: Raad H
authors: RH
authors: Mohiaddin
mesh_terms: D002001:Adipose Tissue, Brown / Q000473:pathology*; D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006338:Heart Neoplasms / Q000175:diagnosis / Q000556:secondary; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine; D010496:Pericardium / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography