title: Prevalence of Hepatitis B and C among Patients Looking for Hospital Care; Five Years' Study in Mashhad, Iran.
abstract: This study was conducted to find out the prevalence, viral load and co-infection of HBV and HCV infection among patients seeking to hospital care in Mashhad, Iran. A total of 402 samples (349 samples for HBV and 53 for HCV) were received and were screened for hepatitis B and C during 2004 to 2014. Viral loads of HBV DNA and HCV RNA were quantified by real-time PCR. Among 349 collected samples, 229 (65.61%) were positive for HBV DNA and 36 (67.92%) for HCV RNA. Among the ones positive for HBV DNA and HCV RNA, HCV was more prevalent (86.11% Vs 58%) ,in male patients, a higher incidence was attributed to HBV than HCV (34.42 Vs 13.88%%). The incidence of co-infection of HBV and HCV was in 5 (1.88%) patients. Association of age and load of HBV, HCV showed that higher marginal viral loads found to be more common in the age groups of upper 30 years old (P=0.064, P=0.079, respectively). The present study provides the preliminary information about high HCV and HBV prevalence. Findings from the current study will be helpful for the better management and control of viral hepatitis among patients looking for hospital care.
authors: Microbiology and Virology Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Atefeh
authors: A
authors: Yari
authors: Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Hadis
authors: H
authors: Yousefzadeh
authors: Microbiology and Virology Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Sahar
authors: S
authors: Tahaghoghi
authors: Microbiology and Virology Research Center, Ghaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
authors: Kiarash
authors: K
authors: Ghazvini
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D060085:Coinfection; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology*; D006526:Hepatitis C / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D060888:Real-Time Polymerase Chain Reaction; D019562:Viral Load; D055815:Young Adult
keywords: Gender; Hepatitis B virus; Hepatitis C virus; Real Time PCR; Viral load