title: Clinical impact of low-burden BCR-ABL1 mutations detectable by amplicon deep sequencing in Philadelphia-positive acute lymphoblastic leukemia patients.
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: S
authors: 0000-0002-4508-0353
authors: S
authors: Soverini
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: C
authors: C
authors: De Benedittis
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: C
authors: C
authors: Papayannidis
authors: Institute of Hematology and Blood Transfusion, Prague, Czech Republic.
authors: K Machova
authors: KM
authors: Polakova
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: C
authors: C
authors: Venturi
authors: Chair of Hematology, Unit of Blood Diseases and Stem Cell Transplantation, University of Brescia, Brescia, Italy.
authors: D
authors: D
authors: Russo
authors: Bone Marrow Transplant Unit, Department of Oncology and Hematology, University of Modena, Modena, Italy.
authors: P
authors: P
authors: Bresciani
authors: Onco-Hematology Division, IRCCS Ca' Granda-Maggiore Policlinico Hospital Foundation, Milan, Italy.
authors: A
authors: A
authors: Iurlo
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: M
authors: M
authors: Mancini
authors: Hematology, Department of Cellular Biotechnologies and Hematology, La Sapienza University, Rome, Italy.
authors: A
authors: A
authors: Vitale
authors: Hematology, Department of Cellular Biotechnologies and Hematology, La Sapienza University, Rome, Italy.
authors: S
authors: S
authors: Chiaretti
authors: Hematology, Department of Cellular Biotechnologies and Hematology, La Sapienza University, Rome, Italy.
authors: R
authors: R
authors: Foà
authors: Hematology, S. Eugenio Hospital, Tor Vergata University, Rome, Italy.
authors: E
authors: E
authors: Abruzzese
authors: Hematology, Università Cattolica del Sacro Cuore, Rome, Italy.
authors: F
authors: F
authors: Sorà
authors: Personalised Healthcare and Biomarkers, AstraZeneca, Cambridge, UK.
authors: A
authors: A
authors: Kohlmann
authors: MLL Munich Leukemia Laboratory, Munich, Germany.
authors: T
authors: T
authors: Haferlach
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: M
authors: M
authors: Baccarani
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: M
authors: M
authors: Cavo
authors: Department of Experimental, Diagnostic and Specialty Medicine, Hematology/Oncology 'L. e A. Seràgnoli', University of Bologna, Bologna, Italy.
authors: G
authors: G
authors: Martinelli
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use; D004252:DNA Mutational Analysis / Q000379:methods*; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D005260:Female; D016044:Fusion Proteins, bcr-abl / Q000037:antagonists & inhibitors / Q000235:genetics*; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009154:Mutation; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000235:genetics; D018365:Neoplasm, Residual / Q000175:diagnosis / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; C581634:BCR-ABL1 fusion protein, human; D047428:Protein Kinase Inhibitors; D016044:Fusion Proteins, bcr-abl