title: [Principles and applications of susceptibility weighted imaging].
abstract: BACKGROUND
  Susceptibility-weighted imaging (SWI), initially developed to provide an improved method for cerebral magnetic resonance (MR) venography, is now an integral part of neuroradiological diagnostics and is steadily gaining importance in non-cerebral imaging.
  
  
  BACKGROUND
  Tissue-inherent susceptibility differences generate a local magnetic field in which the dephasing of signal-producing protons occurs. This leads to a characteristic phase shift that can be used as a means to enhance contrast in the well-known T2*-weighted imaging.
  Many medically relevant pathologies induce tissue alterations that also influence the magnetic properties of tissue. Thus, the detection of blood residues and calcifications in SWI is superior to conventional MR sequences.
  
  
  CONCLUSIONS
  New techniques, such as quantitative susceptibility mapping (QSM) and susceptibility tensor imaging (STI) allow improved differentiation between blood residues and calcifications and provide an alternative imaging method for fiber tractography with respect to diffusion tensor imaging.
authors: Radiologie E010, INF 280, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland.|Abteilung für Neuroradiologie, INF 400, Universitätsklinikum Heidelberg, 69120, Heidelberg, Deutschland.
authors: F T
authors: FT
authors: Kurz
authors: Radiologie E010, INF 280, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland.
authors: M
authors: M
authors: Freitag
authors: Radiologie E010, INF 280, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland.
authors: H-P
authors: HP
authors: Schlemmer
authors: Abteilung für Neuroradiologie, INF 400, Universitätsklinikum Heidelberg, 69120, Heidelberg, Deutschland.
authors: M
authors: M
authors: Bendszus
authors: Radiologie E010, INF 280, Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, 69120, Heidelberg, Deutschland. c.ziener@dkfz-heidelberg.de.|Abteilung für Neuroradiologie, INF 400, Universitätsklinikum Heidelberg, 69120, Heidelberg, Deutschland. c.ziener@dkfz-heidelberg.de.
authors: C H
authors: CH
authors: Ziener
mesh_terms: D003198:Computer Simulation; D056324:Diffusion Tensor Imaging / Q000379:methods*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008954:Models, Biological; D010690:Phlebography / Q000379:methods*
keywords: Calcification; Hemorrhage; Magnetic susceptibility; Phase imaging; Susceptibility-weighted imaging (SWI)