title: [PLATELET AGGREGATION IN CLINICALLY HEALTHY PERSONS OF THE SECOND COMING OF AGE LIVING IN THE KURSK REGION].
abstract: This work is dedicated to the study of the aggregation of platelet activity in healthy persons the second coming of age. The study group included 146 clinically healthy people of the second coming of age, leading a healthy lifestyle and not having metabolic and cardiovascular diseases. In healthy people of 36-45 years noted the lack of reliable antioxidant dynamics of platelets and levels of lipid peroxidation. Platelet aggregation with a range of inductors in people of 36-60 years confirmed the age-dependent increase of aggregation platelet function. After 45 years of age, the activity of platelet aggregative in healthy people increases gradually, leading to an increase in their blood platelet active forms, which inevitably leads to the increase in the number of circulating units of various sizes. This tendency is accompanied by painful with age, increasing negative impact of environmental factors, contributing to the realization of a genetic predisposition to various, primarily cardiovascular, diseases.
authors: N V
authors: NV
authors: Kutafina
authors: I N
authors: IN
authors: Medvedev
mesh_terms: D000328:Adult; D000375:Aging / Q000097:blood*; D001777:Blood Coagulation / Q000502:physiology*; D001792:Blood Platelets / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010974:Platelet Aggregation / Q000502:physiology*; D012016:Reference Values; D012426:Russia; D055815:Young Adult