title: Prevalence of HPV infection among 28,457 Chinese women in Yunnan Province, southwest China.
abstract: Human papillomavirus (HPV) infection plays a key role in the development of cervical cancer. The aim of the current study was to investigate the HPV type distribution in Chinese women from Yunnan Province, southwest China. A total of 28,457 individuals ranging in age from 17-84 years were recruited from 13 clinical hospitals located in 10 different regions of Yunnan Province. Cervicovaginal swabs were collected from each participant, and HPV screening was performed using Luminex xMAP technology. Our results showed that the HPV prevalence was 12.9% in Yunnan Province. Overall, 10.6% of the individuals were positive for a single HPV type, and 2.3% were positive for multiple types. Among the individuals who tested positive for a single HPV type and multiple HPV types, the three most prevalent high-risk types were 52, 16, and 58. Age subgroup analysis showed two peaks for the frequencies of single and multiple HPV infections, one for the group of women under 25 years old, and the other for the group over 56 years old. Here, we present data regarding the prevalence and type distribution of HPV infection, which will aid in the estimation of the potential clinical benefit and cost-effectiveness of HPV screening and vaccination in China.
authors: Department of Laboratory, Yan'an Hospital of Kunming, Kunming 650051, China.
authors: Zheng
authors: Z
authors: Li
authors: Department of Laboratory, General Hospital of Yunnan Armed Police Force, Kunming 650111, China.
authors: Feng
authors: F
authors: Liu
authors: Department of Laboratory, Yan'an Hospital of Kunming, Kunming 650051, China.
authors: Si
authors: S
authors: Cheng
authors: Institute of Medical Biology, Chinese Academy of Medical Sciences &Peking Union Medical College, Kunming 650118, China.
authors: Lei
authors: L
authors: Shi
authors: Department of Gynaecologic Oncology, The 3rd Affiliated Hospital of Kunming Medical University &Yunnan Tumour Hospital, Kunming 650118, China.
authors: Zhiling
authors: Z
authors: Yan
authors: Wenzhou Medical University, Wenzhou 325035, China.
authors: Jie
authors: J
authors: Yang
authors: Institute of Medical Biology, Chinese Academy of Medical Sciences &Peking Union Medical College, Kunming 650118, China.
authors: Li
authors: L
authors: Shi
authors: Institute of Medical Biology, Chinese Academy of Medical Sciences &Peking Union Medical College, Kunming 650118, China.
authors: Yufeng
authors: Y
authors: Yao
authors: Institute of Medical Biology, Chinese Academy of Medical Sciences &Peking Union Medical College, Kunming 650118, China.
authors: Yanbing
authors: Y
authors: Ma
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000145:classification*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D015995:Prevalence; D014626:Vaginal Smears