title: Particle Radiation Therapy for Gastrointestinal Cancers.
abstract: Particle irradiation of cancerous disease has gained great traction in recent years. The ability for particle therapy centers to deliver radiation with a highly conformal dose distribution while maintaining minimal exit or excess dose delivered to normal tissue, coupled with various biological advantages particularly found with heavy-ion beams, enables treatment of diseases inapproachable with conventional radiotherapy. Here, we present a review of the current status of particle therapy with regard to cancers of the gastrointestinal tract, including esophagus, liver, pancreas, and recurrent rectal cancer.
authors: Ion Beam Therapy Center, SAGA HIMAT Foundation, Saga, Japan.
authors: Makoto
authors: M
authors: Shinoto
authors: Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan.|Brown University Alpert Medical School, Providence, RI, USA.
authors: Daniel K
authors: DK
authors: Ebner
authors: Research Center Hospital for Charged Particle Therapy, National Institute of Radiological Sciences, Chiba, Japan. s_yamada@nirs.go.jp.
authors: Shigeru
authors: S
authors: Yamada
mesh_terms: D004938:Esophageal Neoplasms / Q000532:radiotherapy; D005770:Gastrointestinal Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008113:Liver Neoplasms / Q000532:radiotherapy; D009364:Neoplasm Recurrence, Local / Q000532:radiotherapy; D010190:Pancreatic Neoplasms / Q000532:radiotherapy; D061766:Proton Therapy / Q000379:methods*; D012004:Rectal Neoplasms / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery
keywords: Carbon-ion radiotherapy; Gastrointestinal cancer; Particle radiotherapy; Proton beam therapy