title: Evaluation of Neurodevelopment and Factors Affecting it in Children With Acyanotic Congenital Cardiac Disease.
abstract: BACKGROUND
  The rate of congenital heart disease is 0.8% in all live births. The majority of this, however, is acyanotic congenital heart disease. The survival rate of children with cardiac disease has increased with the developments provided in recent years and their lifetime is extended.
  
  
  OBJECTIVE
  This study aims to evaluate neurodevelopment of children with uncomplicated acyanotic congenital heart disease in preschool period and determine the factors affecting their neurodevelopmental process.
  
  
  METHODS
  132 children with acyanotic congenital heart disease aged 6 - 72 months were involved in the study. Mental development and intelligence levels of patients under 2 years old were assessed by using Bayley Development Scale-III, and Stanford Binet Intelligence test was employed for patients over 2 years old. Denver Developmental Screening Test II was applied to all patients for their personal-social, fine motor, gross motor and language development.
  
  
  RESULTS
  The average age of patients (67 girls, 65 boys) included in the study was 35.2 ± 19.6 months. It was determined that there were subnormal mental level in 13 (10%) patients and at least one specific developmental disorder in 33 (25%) patients. Bayley Mental Development Scale score of patients who had received incubator care in perinatal period was found significantly low (88 ± 4.2) compared to those with no incubator care (93.17 ± 8.5) (P = 0.028). Low educational level of father was established to be linked with low mental development scores at the age of 2 and following that age (P < 0.05). Iron deficiency anemia was discovered to be related to low psychometric test scores at every age (P < 0.05).
  
  
  CONCLUSIONS
  Neurodevelopmental problems in children with acyanotic congenital heart disease were found higher compared to those in society. Mental development and intelligence levels of patients were determined to be closely associated with receiving incubator care, father's educational level and iron deficiency anemia.
authors: Department of Pediatrics, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Ayten
authors: A
authors: Ozmen
authors: Pediatric Cardiology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Semiha
authors: S
authors: Terlemez
authors: Pediatric Cardiology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Fatma Sedef
authors: FS
authors: Tunaoglu
authors: Department of Pediatrics, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Sebnem
authors: S
authors: Soysal
authors: Pediatric Cardiology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Ayhan
authors: A
authors: Pektas
authors: Pediatric Cardiology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Erman
authors: E
authors: Cilsal
authors: Pediatric Hematology Department, Faculty of Medicine Gazi University, Ankara, Turkey.
authors: Ulker
authors: U
authors: Koca
authors: Pediatric Cardiology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Serdar
authors: S
authors: Kula
authors: Pediatric Cardiology Department, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Ayse
authors: A
authors: Deniz Oguz
keywords: Acyanotic Congenital Heart Disease; Mental Development; Psychometric Assessment