title: Three wall-associated kinases required for rice basal immunity form protein complexes in the plasma membrane.
abstract: Receptor-like kinases (RLKs) play key roles in disease resistance, in particular basal immunity. They recognize patterns produced by the pathogen invasion and often work as complexes in the plasma membrane. Among these RLKs, there is increasing evidence in several plant species of the key role of Wall-associated kinases (WAKs) in disease resistance. We recently showed using rice (Oryza sativa) loss-of-function mutants of three transcriptionally co-regulated OsWAK genes that individual OsWAKs are positively required for quantitative resistance to the rice blast fungus, Magnaporthe oryzae. This finding was unexpected since WAK genes belong to large gene families where functional redundancy is expected. Here we provide evidence that this may be due to complex physical interaction between OsWAK proteins.
authors: b INRA, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
authors: Bastien
authors: B
authors: Cayrol
authors: a CIRAD, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.|b INRA, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
authors: Amandine
authors: A
authors: Delteil
authors: b INRA, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
authors: Enrico
authors: E
authors: Gobbato
authors: b INRA, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
authors: Thomas
authors: T
authors: Kroj
authors: b INRA, UMR BGPI INRA/CIRAD/SupAgro, Campus International de Baillarguet , TA A 54/K, 34398 Montpellier , France.
authors: Jean-Benoit
authors: JB
authors: Morel
mesh_terms: D002462:Cell Membrane / Q000201:enzymology*; D002473:Cell Wall / Q000201:enzymology*; D008954:Models, Biological; D046912:Multiprotein Complexes / Q000378:metabolism*; D012275:Oryza / Q000201:enzymology* / Q000276:immunology*; D057865:Plant Immunity; D010940:Plant Proteins / Q000378:metabolism*; D011485:Protein Binding; D011494:Protein Kinases / Q000378:metabolism*
chemical_list: D046912:Multiprotein Complexes; D010940:Plant Proteins; D011494:Protein Kinases
keywords: Complexes; protein interaction; rice; wall-associated kinase (WAK)