title: [Acute Toxicity of Coptis chinensis Rhizome Extracts to Daphnia carinata].
abstract: Coptis chinensis rhizome and preparations were widely used for the treatment of fish diseases in aquaculture. the acute toxicological effect of CRE on lethal, movement and phototaxis was studied on Daphnia carinata monoclone as a test animal in the present experiment. The results showed that CRE was acute toxic to this animal and alkaloids berberine concentrations in CRE changed in the following sequence: half lethal > half inhibitory > limitable, which led to a significant change in phototaxis index of Daphnia carinata. The concentration of CRE for the significant change in phototaxis index was 4.27 mg x L(-1), which was lower than the concentration in water to cure the fish diseases and this conclusion indicated an ecological risk of this antibiotic to Daphnia carinata in aquaculture. In addition, the concentration of CRE in phototaxis index was changed from 30.62 times at 48th hour to 36.51 times at 24th hour that were lower than half lethal concentration. Detecting phototaxis index was easy and only 3 hours was required, so utilizing the quickly change of Daphnia carinata phototaxis can be an effective method to monitor the toxicity effect of CRE on Daphnia carinata. The abuse of rhizome or preparations in aquaculture might destroy the aquatic food chain, resulting in an imbalance of aquatic ecosystems.
authors: Ya-nan
authors: YN
authors: Chen
authors: Ling
authors: L
authors: Yuan
mesh_terms: D000818:Animals; D017756:Aquaculture; D039323:Coptis / Q000737:chemistry*; D003621:Daphnia / Q000187:drug effects*; D020387:Food Chain; D010936:Plant Extracts / Q000633:toxicity*; D027343:Rhizome / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000633:toxicity
chemical_list: D010936:Plant Extracts; D014874:Water Pollutants, Chemical