title: Electrophoretically prepared hybrid materials for biopolymer hydrogel and layered ceramic nanoparticles.
abstract: BACKGROUND
  In order to obtain biomaterials with controllable physicochemical properties, hybrid biomaterials composed of biocompatible biopolymers and ceramic nanoparticles have attracted interests. In this study, we prepared biopolymer/ceramic hybrids consisting of various natural biopolymers and layered double hydroxide (LDH) ceramic nanoparticles via an electrophoretic method. We studied the structures and controlled-release properties of these materials.
  
  
  CONCLUSIONS
  X-ray diffraction (XRD) patterns and X-ray absorption spectra (XAS) showed that LDH nanoparticles were formed in a biopolymer hydrogel through electrophoretic reaction. Scanning electron microscopic (SEM) images showed that the ceramic nanoparticles were homogeneously distributed throughout the hydrogel matrix. An antioxidant agent (i.e., ferulic acid) was loaded onto agarose/LDH and gelatin/LDH hybrids, and the time-dependent release of ferulic acid was investigated via high-performance liquid chromatography (HPLC) for kinetic model fitting.
  
  
  CONCLUSIONS
  Biopolymer/LDH hybrid materials that were prepared by electrophoretic method created a homogeneous composite of two components and possessed controllable drug release properties according to the type of biopolymer.
authors: Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, #326, Changjo-hall, Wonju Campus, Yonseidaegil 1, Heungeop-myeon, Wonju, Gangwondo 26493 Republic of Korea.
authors: Gyeong-Hyeon
authors: GH
authors: Gwak
authors: Postharvest Research Team, National Institute of Horticultural and Herbal Science (NIHHS) of RDA, Wanju, Jeollabukdo 55365 Republic of Korea.
authors: Ae-Jin
authors: AJ
authors: Choi
authors: Postharvest Research Team, National Institute of Horticultural and Herbal Science (NIHHS) of RDA, Wanju, Jeollabukdo 55365 Republic of Korea.
authors: Yeoung-Seuk
authors: YS
authors: Bae
authors: Postharvest Research Team, National Institute of Horticultural and Herbal Science (NIHHS) of RDA, Wanju, Jeollabukdo 55365 Republic of Korea.
authors: Hyun-Jin
authors: HJ
authors: Choi
authors: Department of Chemistry and Medical Chemistry, College of Science and Technology, Yonsei University, #326, Changjo-hall, Wonju Campus, Yonseidaegil 1, Heungeop-myeon, Wonju, Gangwondo 26493 Republic of Korea.
authors: Jae-Min
authors: JM
authors: Oh
keywords: Agarose; Biopolymer; Ceramic; Controlled release; Electrophoretic synthesis; Gelatin; Layered double hydroxide