title: Gait variability in multiple sclerosis: a better falls predictor than EDSS in patients with low disability.
abstract: This longitudinal study aims to compare the role of stride time variability (STV) and EDSS for predicting falls in 50 patients with multiple sclerosis with low disability. 21.7 % developed falls (follow-up: 22 months). STV (IRR: 1.73, 95 % CI: 1.23-2.41, p = 0.001) and EDSS (IRR: 2.29, 95 % CI: 1.35-3.90, p = 0.002) were associated with the number of falls. Adding STV to EDSS improves the predictive power of the model from 21 to 26 %, but not adding EDSS to STV.
authors: Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland. gilles.allali@hcuge.ch.|Department of Neurology, Albert Einstein College of Medicine, Yeshiva University, New York, USA. gilles.allali@hcuge.ch.
authors: Gilles
authors: G
authors: Allali
authors: Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland.
authors: Magali
authors: M
authors: Laidet
authors: Department of Internal Medicine, Rehabilitation and Geriatrics, Geneva University Hospitals and University of Geneva, Geneva, Switzerland.
authors: Francois R
authors: FR
authors: Herrmann
authors: Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals and Geneva University, Geneva, Switzerland.
authors: Stéphane
authors: S
authors: Armand
authors: Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland.|Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals and Geneva University, Geneva, Switzerland.
authors: Charlotte
authors: C
authors: Elsworth-Edelsten
authors: Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland.
authors: Frédéric
authors: F
authors: Assal
authors: Division of Neurology, Department of Clinical Neurosciences, Geneva University Hospitals and Faculty of Medicine, University of Geneva, 4 Rue Gabrielle-Perret-Gentil, 1211, Geneva, Switzerland.|Division of Laboratory Medicine, Department of Genetic and Laboratory Medicine, University Hospital of Geneva, 1211, Geneva, Switzerland.
authors: Patrice H
authors: PH
authors: Lalive
mesh_terms: D000058:Accidental Falls; D000328:Adult; D004185:Disability Evaluation; D005260:Female; D005684:Gait; D006801:Humans; D008297:Male; D020529:Multiple Sclerosis, Relapsing-Remitting; D012720:Severity of Illness Index
keywords: Disability; Falls; Gait disorders; Longitudinal study; Multiple sclerosis