title: What Is the Real Public Health Significance of Iron Deficiency and Iron Deficiency Anaemia in Croatia? A Population-Based Observational Study on Pregnant Women at Early Pregnancy from Eastern Croatia.
abstract: Studies imply that significance of iron deficiency (ID) and iron deficiency anaemia (IDA) for pregnancy outcomes is especially highlighted in the early pregnancy. Prevalence around the world varies widely, however, no data is available up to date for Croatia or neighbouring countries. Therefore, the objective was to determine the prevalence of ID and IDA among pregnant women from Croatia at the first trimester. Also, the aim was to compare two criterions; the World Health Organization (WHO) one and the clinical one.
  
  
  
  Randomised observational population based study was set up and 265 pregnant women at the first trimester were enrolled.
  
  
  
  Based on the WHO criteria, 17.7% on haemoglobin basis and 18.5% on haematocrit basis had either ID or IDA. Clinical criteria showed that even 32.8% had either ID or IDA (transferrin saturation <20.0%). The WHO criterion shows less sensitivity, especially in detecting less severe stages of IDA.
  
  
  
  Regardless of the criteria used, ID and IDA present a mild to moderate public health problem in pregnant women population. This high share of pregnant women who are starting their pregnancy as iron deficient, presents a potentially high risk for the pregnancy outcomes, especially in terms of a newborn, and it is fully justified to treat them as diseases of public health significance.
authors: Department of Food and Nutrition Research, Faculty of Food Technology, University of Osijek, Osijek, Croatia.
authors: Ines
authors: I
authors: Banjari
authors: Department of Food and Nutrition Research, Faculty of Food Technology, University of Osijek, Osijek, Croatia.
authors: Daniela
authors: D
authors: Kenjerić
authors: Department of Food and Nutrition Research, Faculty of Food Technology, University of Osijek, Osijek, Croatia.
authors: Milena L
authors: ML
authors: Mandić
mesh_terms: D000328:Adult; D018798:Anemia, Iron-Deficiency / Q000453:epidemiology*; D017523:Croatia / Q000453:epidemiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D011250:Pregnancy Complications, Hematologic / Q000453:epidemiology*; D011256:Pregnancy Outcome; D011261:Pregnancy Trimester, First; D015995:Prevalence; D011634:Public Health
keywords: Croatia; early pregnancy; iron deficiency; iron deficiency anaemia; pregnant women