title: The Synthesis of Multifunctionalized 1,3-Oxazin-4-ones from Donor-Acceptor Cyclopropanes.
abstract: A series of electronically diverse imines were found to readily react with various donor-acceptor cyclopropyl acid chlorides, with complete regioselectivity, to form 1,3-oxazin-4-ones in moderate yields (25-48% over two steps). Select oxazinones underwent a base induced rearrangement to afford the corresponding cycloheptene-fused oxazinones in good yields (up to 70%).
authors: Department of Chemistry, University of Otago , Dunedin, New Zealand.
authors: Robert J
authors: RJ
authors: Smith
authors: Department of Chemistry, University of Otago , Dunedin, New Zealand.
authors: Daniel A
authors: DA
authors: Mills
authors: Department of Chemistry, University of Otago , Dunedin, New Zealand.
authors: Duong
authors: D
authors: Nhu
authors: Department of Chemistry, University of Otago , Dunedin, New Zealand.
authors: Eng Wui
authors: EW
authors: Tan
authors: Department of Chemistry, University of Otago , Dunedin, New Zealand.
authors: Nigel T
authors: NT
authors: Lucas
authors: Department of Chemistry, University of Otago , Dunedin, New Zealand.
authors: Bill C
authors: BC
authors: Hawkins