title: Epithelial sodium channels (ENaC) produce extracellular positive DC potentials in the retinal neuroepithelium.
abstract: Positive DC (direct current) potentials were measured in the extracellular space in the retinal neuroepithelium of chick embryos. The positive DC potential was suppressed by amiloride, a blocker for epithelial Na(+) channels (ENaC). Amiloride also decreased the resistance of the extracellular space as measured by passing a constant current through a microelectrode. The positive DC potential is necessary for the guidance of retinal ganglion cell axons [1].
authors: Center for Medical Science, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara 324-8501, Japan.
authors: Masayuki
authors: M
authors: Yamashita