title: Photophysical Properties of the 2-Hydroxytryptanthrin and Its Sodium Salt as Near-infrared Dyes for Fluorescent Imaging.
abstract: 2-Hydroxytryptanthrin (T2OH) and its sodium salt (sodium tryptanthrin-2-olate, T2ONa) were synthesized as near-infrared (NIR) dyes for fluorescent imaging. The absorption maxima (λ(a,max)) of T2OH under a pH range from 1.3 to 7.2 and from 8.5 to 10.6 were ca. 410 nm and ca. 495 nm, respectively. Moreover, the fluorescence maxima (λ(f,max)) were ca. 660 nm regardless of the pH range. T2ONa was water soluble and the λf,max were ca. 660 nm in both aprotic and protic solvents.
authors: Graduate School of Science and Technology, Hirosaki University.
authors: Jun
authors: J
authors: Kawakami
authors: Masahiro
authors: M
authors: Takahashi
authors: Shunji
authors: S
authors: Ito
authors: Haruo
authors: H
authors: Kitahara
mesh_terms: D003952:Diagnostic Imaging; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D010777:Photochemistry / Q000379:methods*; D011799:Quinazolines / Q000138:chemical synthesis*; D052999:Quinazolinones / Q000138:chemical synthesis*; D012492:Salts / Q000737:chemistry*; D012964:Sodium / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D019265:Spectroscopy, Near-Infrared; D014867:Water / Q000737:chemistry
chemical_list: C000611995:2-hydroxytryptanthrin; D005456:Fluorescent Dyes; D011799:Quinazolines; D052999:Quinazolinones; D012492:Salts; D012997:Solvents; D014867:Water; C046243:tryptanthrine; D012964:Sodium