title: A differentially selective probe based on diketopyrrolopyrrole with fluorescence turn-on response to Fe(3+), and dual-mode turn-on and ratiometric response to Au(3+), and its application in living cell imaging.
abstract: A diketopyrrolopyrrole-based probe DPP-PyR was able to recognize Fe(3+) and Au(3+) with fluorescent turn-on response via different emission modes with relatively low detection limit. Moreover, DPP-PyR exhibited preferential second mode of selectivity for Au(3+) as it ratiometrically displaced Fe(3+) from the [DPP-PyR+Fe(3+)] complex. Furthermore, the imaging experiments indicated that this probe was cell-permeable and could be used to detect Fe(3+) and Au(3+) ions within living cell. To the best of our knowledge, it was the first probe for detection Fe(3+) and Au (3+) at the same time ever reported.
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China; Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical Materials, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China. Electronic address: chm_yangxf@ujn.edu.cn.
authors: Xiaofeng
authors: X
authors: Yang
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors: Xiaolei
authors: X
authors: Liu
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors: Yexin
authors: Y
authors: Li
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors: Fan
authors: F
authors: Wu
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors: Jiaxin
authors: J
authors: Mao
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors: Yuan
authors: Y
authors: Yuan
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China. Electronic address: chm_cuiy@ujn.edu.cn.
authors: Yu
authors: Y
authors: Cui
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China. Electronic address: chm_sungx@ujn.edu.cn.
authors: Guoxin
authors: G
authors: Sun
authors: School of Chemistry and Chemical Engineering, University of Jinan, No. 336, West Road of Nan Xinzhuang, Jinan 250022, Shandong, China.
authors: Guangyou
authors: G
authors: Zhang
mesh_terms: D015374:Biosensing Techniques / Q000379:methods; D002412:Cations / Q000032:analysis; D045744:Cell Line, Tumor; D002470:Cell Survival; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D006046:Gold / Q000032:analysis*; D006801:Humans; D007501:Iron / Q000032:analysis*; D061848:Optical Imaging / Q000379:methods*; D011758:Pyrroles / Q000737:chemistry*
chemical_list: D002412:Cations; D005456:Fluorescent Dyes; D011758:Pyrroles; D006046:Gold; D007501:Iron
keywords: Au(3+) ion; Bioimaging; Fe(3+) ion; Multiple–analyte recognition; Ratiometric response; “Turn–on” response