title: Contemporary management of acute and chronic deep venous thrombosis.
abstract: BACKGROUND
  This review aims to provide an update on the management of deep vein thrombosis (DVT).
  
  
  METHODS
  A systematic search of PubMed, Google Scholar and Cochrane databases was carried out.
  
  
  RESULTS
  Direct oral anticoagulants (DOACs) are as effective and easier to use than vitamin K antagonists for the treatment of DVT. Catheter-directed thrombolysis can reduce post thrombotic syndrome in patients with iliofemoral DVT. Compression bandaging can help heal a venous ulcer.
  
  
  RESULTS
  Compression hosiery to prevent post thrombotic syndrome. Long-term evidence to show clinical benefit of using endovenous therapies to restore deep vein patency.
  
  
  CONCLUSIONS
  Developing imaging methods to identify patients who would benefit from venous thrombolysis. The evolution of dedicated venous stents.
  
  
  CONCLUSIONS
  Understanding the mechanisms that lead to stent occlusion and investigation into the appropriate treatments that could prevent in-stent thrombosis is required.
authors.affiliation: Academic Department of Vascular Surgery, King's College London, St. Thomas' Hospital, London SE1 7EH, UK.
authors.forename: Prakash
authors.initials: P
authors.lastname: Saha
authors.affiliation: Academic Department of Vascular Surgery, King's College London, St. Thomas' Hospital, London SE1 7EH, UK.
authors.forename: Stephen
authors.initials: S
authors.lastname: Black
authors.affiliation: Department of Thrombosis and Haemostasis, Guy's and St. Thomas' Hospitals, NHS Foundation Trust, London SE1 7EH, UK.
authors.forename: Karen
authors.initials: K
authors.lastname: Breen
authors.affiliation: Academic Department of Vascular Surgery, King's College London, St. Thomas' Hospital, London SE1 7EH, UK.
authors.forename: Ashish
authors.initials: A
authors.lastname: Patel
authors.affiliation: Academic Department of Vascular Surgery, King's College London, St. Thomas' Hospital, London SE1 7EH, UK bijan.modarai@kcl.ac.uk.
authors.forename: Bijan
authors.initials: B
authors.lastname: Modarai
authors.affiliation: Academic Department of Vascular Surgery, King's College London, St. Thomas' Hospital, London SE1 7EH, UK.
authors.forename: Alberto
authors.initials: A
authors.lastname: Smith
mesh_terms: D000208:Acute Disease; D000925:Anticoagulants / Q000627:therapeutic use; D002908:Chronic Disease; D006801:Humans; D018579:Patient Selection; D015607:Stents; D017131:Thrombectomy / Q000379:methods; D015912:Thrombolytic Therapy / Q000379:methods; D020246:Venous Thrombosis / Q000000981:diagnostic imaging / Q000628:therapy*
chemical_list: D000925:Anticoagulants
keywords: DVT; catheter-directed lysis; endovenous; post-thrombotic syndrome; thrombolysis; venous stent