title: The Effect of Nasal Septal Perforation and its Treatment on Objective Sleep and Breathing Parameters.
abstract: BACKGROUND Nasal septal perforation (NSP) may alter nasal airflow patterns and physiology. To the best of our knowledge, no studies in the English literature have investigated the effect of NSP and its treatment on polysomnographic parameters. In this study, we aimed to investigate polysomnographic parameters in patients with NSP as well as changes in those parameters after treatment of NSP. MATERIAL AND METHODS Nineteen patients diagnosed with NSP were included in the study. All patients had baseline and post-procedure polysomnographies (PSG) after insertion of silicone septal button for closure of NSP. RESULTS Both median AHI [5.30 (14.40) vs. 2.40 (14.50)] and median supine AHI [10.00 (42.10) vs. 6.60 (37.00)] decreased after correction of the perforation. There was a large reduction in median supine AHI in patients with a perforation size >66 mm2 [10.10 (34.15) vs. 1.60 (28.30)]. CONCLUSIONS We conclude that NSP did not cause any deterioration in objective sleep parameters as determined by PSG, other than a decrease in REM sleep duration and an increase in supine AHI. Correction of NSP did not affect REM duration and supine AHI decreased after treatment.
authors.affiliation: Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Boynuegri
authors.affiliation: Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Melih
authors.initials: M
authors.lastname: Cayonu
authors.affiliation: Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Evrim Unsal
authors.initials: EU
authors.lastname: Tuna
authors.affiliation: Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Selma
authors.initials: S
authors.lastname: Kurukahvecioglu
authors.affiliation: Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Kursat Murat
authors.initials: KM
authors.lastname: Ozcan
authors.affiliation: Department of Otorhinolaryngology, Ankara Numune Education and Research Hospital, Ankara, Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Turkay
authors.affiliation: Department of Otorhinolaryngology, Eskisehir Osmangazi University, Eskisehir, Turkey.
authors.forename: Cemal
authors.initials: C
authors.lastname: Cingi
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D061270:Nasal Septal Perforation / Q000503:physiopathology* / Q000628:therapy*; D017286:Polysomnography / Q000379:methods; D012119:Respiration; D012890:Sleep / Q000502:physiology; D020181:Sleep Apnea, Obstructive / Q000209:etiology / Q000628:therapy*; D012893:Sleep Wake Disorders / Q000628:therapy