title: Adhesions and endometriosis: challenges in subfertility management : (An expert opinion of the ANGEL-The ANti-Adhesions in Gynaecology Expert PaneL-group).
abstract: There is molecular evidence that endometriosis has a negative impact on the ovaries, although the exact pathophysiology concerning endometriosis-associated subfertility is not known. The negative impact on the tubo-ovarian unit can be directly by distorting the anatomy, indirectly by invoking inflammation or by oxidative damage with poorer-quality oocytes. Endometriosis even seems to have a negative effect on pregnancy outcome after in vitro fertilization.
authors.affiliation: Clinic of Gynecology, Obstetrics and Gynecological Oncology, University Hospital for Gynecology, Pius-Hospital Oldenburg, Medical Campus University of Oldenburg, Oldenburg, Germany. rudy-leon.dewilde@pius-hospital.de.
authors.forename: R L
authors.initials: RL
authors.lastname: De Wilde
authors.affiliation: Hospital Universitario Infanta Sofía, Paseo de Europa, 34, 28702, San Sebastián de Los Reyes, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Alvarez
authors.affiliation: Department of Obstetrics and Gynecology, VU University, 1081, Amsterdam, The Netherlands.
authors.forename: H
authors.initials: H
authors.lastname: Brölmann
authors.affiliation: Leuven Institute for Fertility and Embryology (LIFE), Tiensevest 168, 3000, Louvain, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Campo
authors.affiliation: Human Development and Health Unit, University of Southampton and Complete Fertility Centre, Southampton, UK.
authors.forename: Y
authors.initials: Y
authors.lastname: Cheong
authors.affiliation: Department of Obstetrics and Gynecology, Privathospitalet Mølholm, 7100, Vejle, Denmark.
authors.forename: P
authors.initials: P
authors.lastname: Lundorff
authors.affiliation: Division of Infertility and Reproductive Endocrinology, Poznan University of Medical Sciences, Poznan, Poland.
authors.forename: L
authors.initials: L
authors.lastname: Pawelczyk
authors.affiliation: Hopitaux De Rouen, Clinique Gynecologique et Obstetricale, 1 Rue Germont, 76031, Rouen Cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Roman
authors.affiliation: Studio medico, via San Giacomo dei Capri 63, Naples, Italy.
authors.forename: A
authors.initials: A
authors.lastname: di Spiezio Sardo
authors.affiliation: Department of Obstetrics and Gynecology, University Clinic Heidelberg, 69120, Heidelberg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Wallwiener
mesh_terms: D004715:Endometriosis / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D005307:Fertilization in Vitro; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects; D006176:Gynecology; D006801:Humans; D007247:Infertility, Female; D009865:Oocytes; D010053:Ovary; D011183:Postoperative Complications; D011247:Pregnancy; D011256:Pregnancy Outcome; D000267:Tissue Adhesions / Q000209:etiology
keywords: Adhesion prophylactic agents; Adhesions; Endometriosis; Subfertility management