title: Has a mixture of amino acids and micronutrients influence on glucose metabolism and dietary fatty acid pattern in chronic psychosocially stressed persons? A pilot study.
abstract: Brain food, e.g. L-tryptophan, antioxidative substances, B vitamins and magnesium are thought to be beneficial for obesity, inflammation and insulin resistance. In the present pilot study we hypothesised that a specific amino acid mixture with micronutrients improves the cardiometabolic situation of chronically stressed persons. Cardiovascular and metabolic parameters were analysed as per protocol in 32 patients. Chronic stress disorders in the same patients were assessed by a psychological neurological questionnaire (PNF). After dietary intervention a reduction of the fasting serum insulin concentrations occurred in the treatment group. An association was found between PNF values, insulin concentrations at baseline and an insulin reduction after 12 weeks. The results support the use of our specific dietary supplement for improved stress management and a decrease in metabolic dysfunction.
authors.affiliation: a Department of Biostatistics , Medicine and Service Ltd , Chemnitz , Germany ;
authors.forename: Norman
authors.initials: N
authors.lastname: Bitterlich
authors.affiliation: b Bonn Education Association for Dietetics r. A. , Cologne , Germany ;
authors.forename: Katrin
authors.initials: K
authors.lastname: Chaborski
authors.affiliation: c Outpatient Practise of Cardiology/Angiology , Berlin , Germany ;
authors.forename: Elke
authors.initials: E
authors.lastname: Parsi
authors.affiliation: b Bonn Education Association for Dietetics r. A. , Cologne , Germany ;
authors.forename: Daniela
authors.initials: D
authors.lastname: Rösler
authors.affiliation: b Bonn Education Association for Dietetics r. A. , Cologne , Germany ;|d Department of Internal Medicine III , University Hospital, RWTH , Aachen , Germany.
authors.forename: Christine
authors.initials: C
authors.lastname: Metzner
mesh_terms: D000293:Adolescent; D000328:Adult; D000596:Amino Acids / Q000494:pharmacology*; D001786:Blood Glucose; D002318:Cardiovascular Diseases; D004041:Dietary Fats / Q000378:metabolism*; D019587:Dietary Supplements; D005227:Fatty Acids; D005260:Female; D005947:Glucose / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012307:Risk Factors; D013315:Stress, Psychological; D055815:Young Adult
chemical_list: D000596:Amino Acids; D001786:Blood Glucose; D004041:Dietary Fats; D005227:Fatty Acids; D005947:Glucose
keywords: Brain food; dietary supplement; insulin resistance; n-3 fatty acids; stress management; sympathetic nervous system