title: Response to letter to editor.
authors.affiliation: Department of Intensive Care Medicine, Radboud University Medical Center, PO Box 9101, Internal Mailbox 710, 6500 HB Nijmegen, The Netherlands; Department of Pharmacology and Toxicology, Radboud University Medical Center, PO Box 9101, Internal Mailbox 149, 6500 HB Nijmegen, The Netherlands.
authors.forename: Esther
authors.initials: E
authors.lastname: Peters
authors.affiliation: Centre for Human Drug Research, Zernikedreef 8, 2333 CL Leiden, The Netherlands.
authors.forename: Jasper
authors.initials: J
authors.lastname: Stevens
authors.affiliation: Department of Intensive Care Medicine, Radboud University Medical Center, PO Box 9101, Internal Mailbox 710, 6500 HB Nijmegen, The Netherlands. Electronic address: Peter.Pickkers@radboudumc.nl.
authors.forename: Peter
authors.initials: P
authors.lastname: Pickkers