title: The Current Approach to Diagnosis and Management of Left Ventricular Noncompaction Cardiomyopathy: Review of the Literature.
abstract: Isolated left ventricular noncompaction (LVNC) is a genetic cardiomyopathy characterized by prominent ventricular trabeculations and deep intertrabecular recesses, or sinusoids, in communication with the left ventricular cavity. The low prevalence of patients with this cardiomyopathy presents a unique challenge for large, prospective trials to assess its pathogenesis, management, and outcomes. In this paper we review the embryology and genetics of LVNC, the diagnostic approach, and propose a management approach based on the current literature available.
authors.affiliation: Mayo Clinic, 200 First Street SW, Rochester, MN 55902, USA.
authors.forename: Courtney E
authors.initials: CE
authors.lastname: Bennett
authors.affiliation: Lehigh Valley Health Network, 1250 S Cedar Crest Boulevard, Allentown, PA 18103, USA.
authors.forename: Ronald
authors.initials: R
authors.lastname: Freudenberger