title: Acellular dermal matrices in breast reconstructions - a literature review.
abstract: During the last two decades, acellular dermal matrices (ADM) have been more widely used in reconstructive procedures i.e. breast reconstructions. Several, both synthetic and biologic products derived from human, porcine and bovine tissue, have been introduced. Until this point postoperative complications for the acellular dermal matrices, as a group, have been the main focus. The purpose of this literature review is to summarize the current knowledge on the each biologic product used in breast reconstructions, including product specific complication frequencies. A systematic search of the literature was performed in the PubMed and EMBASE databases, identifying 55 relevant articles, mainly evidence level III. AlloDerm seems to be associated with severe complicating matters in the reconstructive process compared to other products. This could be due to the higher number of investigating studies relative to the others. The surgical area faces certain challenges comparing results, due to surgical variance, the data collection and follow-up. More well-defined guidelines and more high-evidence randomized studies could increase the overall level of evidence in this area.
authors.affiliation: a Plastic Surgical Research Unit, Department of Plastic Surgery , Aarhus University Hospital , Aarhus , Denmark.
authors.forename: Simon
authors.initials: S
authors.lastname: Skovsted Yde
authors.affiliation: a Plastic Surgical Research Unit, Department of Plastic Surgery , Aarhus University Hospital , Aarhus , Denmark.
authors.forename: Mette Eline
authors.initials: ME
authors.lastname: Brunbjerg
authors.affiliation: a Plastic Surgical Research Unit, Department of Plastic Surgery , Aarhus University Hospital , Aarhus , Denmark.
authors.forename: Tine Engberg
authors.initials: TE
authors.lastname: Damsgaard
mesh_terms: D062088:Acellular Dermis; D003094:Collagen / Q000009:adverse effects; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D011183:Postoperative Complications
chemical_list: C440568:Alloderm; D003094:Collagen
keywords: Acellular dermal matrix; breast reconstruction; postoperative complications