title: Golden angle dual-inversion recovery acquisition coupled with a flexible time-resolved sparse reconstruction facilitates sequence timing in high-resolution coronary vessel wall MRI at 3 T.
abstract: The need for performing dual-inversion recovery (DIR) coronary vessel wall MRI in correspondence to minimal cardiac motion and optimal blood signal nulling is a major challenge. We propose to address this hurdle by combining DIR with a prolonged acquisition window in conjunction with a golden angle radial trajectory and k-t sparse sensitivity encoding (SENSE) reconstruction to enable a flexible a-posteriori selection of optimized imaging parameters.
  
  
  
  Coronary vessel wall data acquisition was performed with DIR golden angle radial imaging in n=15 healthy subjects. Images reconstructed using k-t sparse SENSE and different reconstruction window settings were quantitatively (vessel wall conspicuity, thickness, acquisition, and reconstruction window settings) compared with those obtained with more conventional radial DIR imaging.
  
  
  
  A flexible retrospective selection of the reconstruction window width and position improved vessel wall conspicuity with respect to baseline acquisitions (P < 0.01). Vessel wall thickness remained unchanged (P = nonsignificant (NS)). Temporal window widths were similar for both approaches (P = NS), yet their position within the cardiac cycle differed significantly (P < 0.02).
  
  
  
  A flexible DIR coronary vessel wall MRI technique that alleviates constraints associated with sophisticated sequence timing was proposed. When compared with a more conventional approach, the technique significantly improved image quality. Magn Reson Med 77:961-969, 2017. © 2016 International Society for Magnetic Resonance in Medicine.
authors.affiliation: Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.
authors.forename: Giulia
authors.initials: G
authors.lastname: Ginami
authors.affiliation: Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.|Centre for Biomedical Imaging (CIBM), Lausanne, Switzerland.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Yerly
authors.affiliation: Division of Cardiology and Cardiac MR Center, University Hospital (CHUV), Lausanne, Switzerland.
authors.forename: Pier Giorgio
authors.initials: PG
authors.lastname: Masci
authors.affiliation: Department of Radiology, University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland.|Centre for Biomedical Imaging (CIBM), Lausanne, Switzerland.
authors.forename: Matthias
authors.initials: M
authors.lastname: Stuber
mesh_terms: D000465:Algorithms; D017023:Coronary Angiography / Q000379:methods*; D003331:Coronary Vessels / Q000033:anatomy & histology*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D012815:Signal Processing, Computer-Assisted
keywords: Compressed sensing; Coronary vessel wall; Time-resolved DIR