title: A Case for Nephron Sparing Surgery in the Management of Upper Tract Urothelial Carcinoma.
abstract: Upper tract urothelial carcinoma (UTUC) is rare and its management presents many challenges. Outside of distal ureterectomy for select cases, management has been primarily radical nephroureterectomy. Endoscopic nephron sparing management (NSM) is recognized to have some role in UTUC treatment; however, it is yet to gain firm footing in the treatment algorithm. In this review, we discuss the benefits of NSM with regards to oncologic outcomes, renal function preservation, and cost savings. Finally, we propose recognition of endoscopic NSM as a first-line treatment in selected patients with low risk disease.
authors.affiliation: 1 Department of Urology, Yale University , New Haven, Connecticut.
authors.forename: Piruz
authors.initials: P
authors.lastname: Motamedinia
authors.affiliation: 2 The Smith Institute for Urology, Hofstra Northwell School of Medicine , New Hyde Park, New York.
authors.forename: David
authors.initials: D
authors.lastname: Hoenig
authors.affiliation: 2 The Smith Institute for Urology, Hofstra Northwell School of Medicine , New Hyde Park, New York.
authors.forename: Zeph
authors.initials: Z
authors.lastname: Okeke
authors.affiliation: 2 The Smith Institute for Urology, Hofstra Northwell School of Medicine , New Hyde Park, New York.
authors.forename: Arthur
authors.initials: A
authors.lastname: Smith
mesh_terms: D002277:Carcinoma / Q000601:surgery*; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000191:economics / Q000379:methods*; D009399:Nephrons; D059351:Organ Sparing Treatments / Q000191:economics / Q000379:methods*; D016896:Treatment Outcome; D014516:Ureteral Neoplasms / Q000601:surgery*