title: IMMUNOMODULATION AND TREATMENT OF ACUTE DESTRUCTIVE PANCREATITIS IN A MULTIDISCIPLINARY SURGICAL HOSPITAL.
abstract: This work is based on the analysis of complex treatment of 497 patients with pancreatic necrosis treated at the surgical department of the Republican Hospital No2-Center for Emergency the Republic of Sakha (Yakutia) in the period from 2010 to 2015. The study was able to adapt and improve the two-tier immunocorretion in pancreatic necrosis in a multidisciplinary surgical hospital that along with the other constituents of intensive therapy has allowed a whole to reduce the amount of intra-abdominal and extraabdominal complications--sterile pancreatic necrosis phase--from 23.6% to 14.6 and 31 6% to 15.0% respectively, total lethality--from 17.6% to 7.2% lethality in patients with non-operated group--from 15.6% to 2.2% lethality in the group of patients operated--18.4% to 10.9%. In the phase of infectious complications of pancreatic necrosis lethality rate decreased from 45.8% to 37.7%.
authors.forename: M M
authors.initials: MM
authors.lastname: Vinokurov
authors.forename: V V
authors.initials: VV
authors.lastname: Saveliev
authors.forename: N M
authors.initials: NM
authors.lastname: Gogolev
authors.forename: T V
authors.initials: TV
authors.lastname: Yalynskya
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006801:Humans; D056747:Immunomodulation; D008297:Male; D010195:Pancreatitis / Q000453:epidemiology / Q000276:immunology* / Q000628:therapy*; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology