title: [Usefulness of imaging in large vessel vasculitis].
abstract: The imaging is essential for the diagnosis of large vessels arteritis, in order to assess the persistent inflammation of arterial lesions, to evaluate the treatment response and search the vascular complications. In patients with giant cell arteritis (GCA), the aortitis could be suspected in 2 situations: in the presence of general constitutional symptoms or systematic screening of aortitis in patient with confirmed GCA. The frequency of aortitis varies according to the imaging method and could be detected in 40 % of patients with computed tomography and MRI, and approximately in 60 % with FDG-PET/CT. The clinical and prognostic value of systematic detection of aortitis during the GCA remains to be determined. In Takayasu arteritis, imaging is performed to diagnose the large vessels vasculitis, to determine the arterial lesions extension to assess the persistent inflammation of arterial lesions. The persistent vascular inflammation should be suspected in the presence of arterial thickness, of arterial enhancement, a parietal edema and increased arterial FDG uptake (>liver). However, the value of these parameters and the threshold remain to be determined. Thus, the value of FDG-PET/CT and MRI and of parameters used to characterize the persistent arterial inflammation should be further studied.
authors.affiliation: Service de médecine interne, département inflammation-immunopathologie biothérapie (DHU i2B), hôpital Saint-Antoine, AP-HP, Sorbonne universités, UPMC université Paris 6, 75012 Paris, France. Electronic address: arsene.mekinian@sat.aphp.fr.
authors.forename: A
authors.initials: A
authors.lastname: Mekinian
authors.affiliation: Service de médecine nucléaire, hôpital Avicenne, AP-HP, Paris Sorbonne Cité, UPMC université Paris 13, 93000 Bobigny, France.
authors.forename: S
authors.initials: S
authors.lastname: Djelbani
authors.affiliation: Service de radiologie, hôpital Saint-Antoine, AP-HP, Sorbonne universités, UPMC université Paris 6, 75012 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Viry
authors.affiliation: Service de médecine interne, département inflammation-immunopathologie biothérapie (DHU i2B), hôpital Saint-Antoine, AP-HP, Sorbonne universités, UPMC université Paris 6, 75012 Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Fain
authors.affiliation: Service de médecine nucléaire, hôpital Avicenne, AP-HP, Paris Sorbonne Cité, UPMC université Paris 13, 93000 Bobigny, France.
authors.forename: M
authors.initials: M
authors.lastname: Soussan
mesh_terms: D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D013700:Giant Cell Arteritis / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000628:therapy; D006801:Humans; D011237:Predictive Value of Tests; D011379:Prognosis; D016896:Treatment Outcome
keywords: Artérite à cellules géantes; Giant cell arteritis; IRM; Imagerie; Imaging; Large vessels vasculitis; MRI; Maladie de Takayasu; PET; Scanner; TEP; Takayasu arteritis; Tomography; Vascularites des gros vaisseaux