title: Evaluation of epidemiological and clinical features of influenza and other respiratory viruses.
abstract: OBJECTIVE
  In our study, we aimed to clinically and epidemiologically evaluate respiratory tract infections the viral agents of which were detected by molecular methods and to compare influenza and other respiratory tract viruses in this context.
  
  
  METHODS
  The records of 178 patients aged above 2 years who presented to pediatric emergency outpatient clinic with fever and respiratory tract infection findings between December 2013 and April 2014 were examined retrospectively.
  
  
  RESULTS
  At least one respiratory tract pathogen was detected by polymerase chain reaction in 78.6% (n=140) of the patients: influenza A 33.5%, influenza B 16.4%, respiratory syncytial virus 9.2%, adenovirus 7.8%, rhinovirus 7.1%, coronavirus 7.1%, human metapneumovirus 5.7%, human bocavirus 5.7%, parainfluenza virus 3.5%, coinfection 2.8%. The mean age of the patients was 6.3±3.6 years. Sixty-nine patients (49.2%) were aged between 2 and 5 years. Seventy-one patients (50.7%) were aged 5 years and above. Upper respiratory tract infection was found with a rate of 65.7% and lower respiratory tract infection was found with a rate of 34.2%. It was observed that the distribution of respiratory tract viruses showed variance by age groups. Influenza A infection was observed with the highest rate in both age groups. Influenza B was the second leading agent (p=0.008) above the age of 5 years and respiratory syncytial virus was the second leading agent in the 2-5 year age group (p=0.003). Influenza viruses were detected in 55.9% of 118 patients who were found to be compatible with the definition of "influenza-like illness" specified in the Center for Disease Control and Prevention guidelines and other viral agenst were detected in 44%. No difference could be found between the clinical pictures and radiological findings caused by influenza and other respiratory tract viruses.
  
  
  CONCLUSIONS
  In this study, it was concluded that influenza and other respiratory viruses can not be differentiated definitely by clinical and radiological findings, though there are some differences.
authors.affiliation: Department of Pediatrics, Division of Pediatric Infection, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Hacer
authors.initials: H
authors.lastname: Aktürk
authors.affiliation: Department of Pediatrics, Division of Pediatric Infection, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Sütçü
authors.affiliation: Department of Microbiology, Division of Virology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Selim
authors.initials: S
authors.lastname: Badur
authors.affiliation: Department of Pediatrics, Division of Pediatric Infection, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Selda Hançerli
authors.initials: SH
authors.lastname: Törün
authors.affiliation: Department of Pediatrics, Division of Pediatric Emergency and Intensive Care, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Agop
authors.initials: A
authors.lastname: Çıtak
authors.affiliation: Department of Radiology, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Oğuz Bülent
authors.initials: OB
authors.lastname: Erol
authors.affiliation: Department of Pediatrics, Division of Pediatric Infection, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Ayper
authors.initials: A
authors.lastname: Somer
authors.affiliation: Department of Pediatrics, Division of Pediatric Infection, İstanbul University İstanbul Faculty of Medicine, İstanbul, Turkey.
authors.forename: Nuran
authors.initials: N
authors.lastname: Salman
keywords: Acute respiratory tract infections; influenza; respiratory viruses