title: A cross-sectional study to evaluate the associations between hypertension and osteoporosis in Chinese postmenopausal women.
abstract: BACKGROUND
  This relationship between hypertension (HTN) and osteoporosis (OP) is not well documented among the population in China. The study sought to study the relationship between HTN and OP in Chinese postmenopausal women.
  
  
  METHODS
  This cross-sectional study involved 1878 Chinese postmenopausal women with an average age of 62.38 years. OP was diagnosed by standardized quantitative ultrasound at the calcaneus and HTN was defined by blood pressure data and/or the use of antihypertensive medication. The relationship for OP and HTN were calculated using univariate and multivariate regression analyses.
  
  
  RESULTS
  The prevalence of OP was 28.17% in the postmenopausal women, and there was a significant difference in the prevalence of OP between the two groups according to HTN (P value = 0.003). Univariate analysis demonstrates a positive correlation between HTN and OP. After adjustment for relevant potential confounding factors, multivariate logistic regression analyses detected significant associations between HTN and OP (P value = 0.096). In participants with HTN, the OR for OP was 1.209 (95% CI: 0.967-1.513).
  
  
  CONCLUSIONS
  The prevalence of OP was more frequent in Chinese postmenopausal women with HTN, and HTN was independently and significantly associated with OP.
authors.affiliation: Department of Cardiology, Huashan Hospital, Fudan University Shanghai, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tongji Hospital, School of Medicine, Tongji University Shanghai, China.
authors.forename: Keqin
authors.initials: K
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Huashan Hospital, Fudan University Shanghai, China.
authors.forename: Haiming
authors.initials: H
authors.lastname: Shi
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tongji Hospital, School of Medicine, Tongji University Shanghai, China.
authors.forename: Zihui
authors.initials: Z
authors.lastname: Tang
keywords: Hypertension; osteoporosis; postmenopausal women