title: Investigation of Helicobacter pylori antigen in stool samples of patients with upper gastrointestinal complaints.
abstract: Helicobacter pylori infection is usually acquired in early childhood and it can persist throughout life without antibiotic treatment. This study aimed to compare the accuracy of the noninvasive H. pylori Stool Antigen Test-applied on the stool samples with the invasive gold standart Rapid Urease Test-applied on the gastric biopy samples of patients with upper gastrointestinal complaints. After endoscopy, biopsy and stool specimens were taken in 122 patients. The infection was detected with rapid urease test which is accepted as gold standart test. Rapid, one-step H. pylori card test was applied to all patients stool specimens. In this study 106 of the 122 patients (86.8%) were positive for H. pylori infection, while 16 of the 122 patients (13.2%) were negative. H. pylori card test was negative in 13 of the 16 patients and was positive in 98 of the 106. The sensitivity, specifity, positive and negative predictive values were 92.45%, 81.25%, 97.02%, and 61.90%, respectively. H. pylori card test is rapid, easy, noninvasive and inexpensive methods for detection H. pylori infection. This test showed high sensitivity and specificity. Additionally, it may be a good alternative to invasive tests for the detection of H. pylori infections especially in children.
authors.affiliation: Department of Microbiology, Faculty of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Zeki
authors.initials: Z
authors.lastname: Calik
authors.affiliation: Department of Microbiology, Faculty of Medicine, Kafkas University, Kars, Turkey. Electronic address: murat_karamese@hotmail.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Karamese
authors.affiliation: Department of Microbiology, Faculty of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Acar
authors.affiliation: Department of Histology and Embryology, Faculty of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Selina
authors.initials: S
authors.lastname: Aksak Karamese
authors.affiliation: Department of Nursing, School of Health, Mus Alparslan University, Mus, Turkey.
authors.forename: Yalcin
authors.initials: Y
authors.lastname: Dicle
authors.affiliation: Department of Internal Medicine, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Albayrak
authors.affiliation: Department of Physiology, Faculty of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Serpil
authors.initials: S
authors.lastname: Can
authors.affiliation: Department of Genereal Surgery, Faculty of Medicine, Kafkas University, Kars, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Guvendi
authors.affiliation: Department of Biochemistry, Faculty of Veterinary, Ataturk University, Erzurum, Turkey.
authors.forename: Alpgiray
authors.initials: A
authors.lastname: Turgut
authors.affiliation: Department of Anatomy, Faculty of Medicine, Gazi Osman Pasa University, Tokat, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cicek
authors.affiliation: Department of Microbiology, Faculty of Medicine, Ataturk University, Erzurum, Turkey.
authors.forename: Halil
authors.initials: H
authors.lastname: Yazgi
mesh_terms: D000942:Antigens, Bacterial / Q000032:analysis*; D005243:Feces / Q000737:chemistry / Q000382:microbiology*; D005767:Gastrointestinal Diseases / Q000175:diagnosis*; D016480:Helicobacter pylori / Q000302:isolation & purification*; D006801:Humans; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D000942:Antigens, Bacterial
keywords: H. pylori card test; Helicobacter pylori; Rapid urease test; Upper gastrointestinal complaints