title: Psychometric Validation of the M. D. Anderson Symptom Inventory-Head and Neck Module in the Spanish Language.
abstract: The assessment of cancer-related symptoms requires culturally adapted and psychometrically validated symptom assessment tools. The M. D. Anderson Symptom Inventory-Head and Neck Module (MDASI-HN) is a useful instrument for measuring symptom burden that was specifically developed for head and neck cancer patients.
  
  
  
  To validate the Spanish version of the MDASI-HN.
  
  
  
  We evaluated the psychometric features of the MDASI-HN in patients with head and neck cancer. We evaluated the item-scale correlations and the internal consistency. We conducted principal axis factoring to identify the underlying dimensions as a measure of construct validity. The convergence/concurrent validity was assessed with the University of Washington Quality of Life Questionnaire for Head and Neck Patients, and known-group validity and test-retest reliability also were assessed.
  
  
  
  One hundred thirty patients were included. The mean ± SD age was 60.5 ± 13.6 years; 68% of patients were male, 42% had laryngeal tumors, and 45.9% had Stage III tumors. Forty-seven percent of the patients underwent surgery, 55% underwent radiotherapy, and 36% underwent chemotherapy. The global Cronbach alpha for the HN module was 0.81. The factor analysis identified two factors (Factor 1: speech, mucus, coughing, and constipation; Factor 2: teeth, taste, sores, swallowing, and skin). The correlation with the global score of the University of Washington Quality of Life was -0.68. The difference in the MDASI-HN scores according to Eastern Cooperative Oncology Group performance status was statistically significant (2.72 vs. 4.01, P = 0.006). The intraclass test-retest correlation was 0.62.
  
  
  
  The Spanish version of the MDASI-HN is reliable and valid for evaluating cancer-related symptoms in head and neck cancer patients.
authors.affiliation: Department of Surgery, Universidad de Antioquia, Medellin, Colombia.
authors.forename: Daniel
authors.initials: D
authors.lastname: Sánchez
authors.affiliation: Department of Surgery, Universidad de Caldas, Manizales, Colombia.
authors.forename: Andrés
authors.initials: A
authors.lastname: Chala
authors.affiliation: Department of Surgery, Universidad del Rosario, Bogota, Colombia.
authors.forename: Andrés
authors.initials: A
authors.lastname: Alvarez
authors.affiliation: Oncology Unit, Hospital Pablo Tobón Uribe, Medellin, Colombia.
authors.forename: Catalina
authors.initials: C
authors.lastname: Payan
authors.affiliation: Department of Symptom Research, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Tito
authors.initials: T
authors.lastname: Mendoza
authors.affiliation: Department of Symptom Research, The University of Texas M. D. Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Charles
authors.initials: C
authors.lastname: Cleeland
authors.affiliation: Department of Surgery, Universidad de Antioquia, Medellin, Colombia; Oncology Unit, Hospital Pablo Tobón Uribe, Medellin, Colombia. Electronic address: alvarosanabria@gmail.com.
authors.forename: Alvaro
authors.initials: A
authors.lastname: Sanabria
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005163:Factor Analysis, Statistical; D005260:Female; D006258:Head and Neck Neoplasms / Q000175:diagnosis* / Q000503:physiopathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D011594:Psychometrics; D011788:Quality of Life; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D014175:Translating; D055815:Young Adult
keywords: Head and neck cancer; M. D. Anderson; inventory; quality of life; symptoms