title: Retinal Detachment and Symptomatic Hypercalcemia in a Patient with Sarcoidosis: Unusual Presentation of a Granulomatous Disease.
abstract: Sarcoidosisis amultisystemic granulomatous disease, potentially affecting any organ system of the body. Calcium metabolism disturbances occur in up to 20% of patients, of which hypercalciuria and asymptomatic hypercalcemia are most common. Ocular sarcoid typically presents with anterior chamber manifestations such as uveitis, iritis, and iridocyclitis, but can involve posterior chamber as well. We describe herein a unique presentation of sarcoidosis with retinal detachment and symptomatic hypercalcemia as its first manifestation. Prompt therapy with steroids is indicated in these cases, and an immediate ophthalmology referral cannot be overemphasized.
authors.forename: Arushi
authors.initials: A
authors.lastname: Khurana
authors.forename: Saira
authors.initials: S
authors.lastname: Cherian
authors.forename: Shounak
authors.initials: S
authors.lastname: Majumder
authors.forename: Radhika
authors.initials: R
authors.lastname: Nakrani
authors.forename: Gurukripa N
authors.initials: GN
authors.lastname: Kowlgi
authors.forename: Constantin A
authors.initials: CA
authors.lastname: Dasanu
mesh_terms: D001706:Biopsy; D050071:Bone Density Conservation Agents / Q000008:administration & dosage; D001856:Bone Marrow Examination; D002116:Calcitonin / Q000008:administration & dosage*; D004164:Diphosphonates / Q000008:administration & dosage*; D005440:Fluid Therapy / Q000379:methods; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D006934:Hypercalcemia / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D053685:Laser Therapy / Q000379:methods*; D008198:Lymph Nodes / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009887:Ophthalmoscopy / Q000379:methods; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D012507:Sarcoidosis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D050071:Bone Density Conservation Agents; D004164:Diphosphonates; D005938:Glucocorticoids; D002116:Calcitonin