title: Psychiatric disease as a risk factor in fast-track hip and knee replacement.
abstract: Recent studies suggest that patients with psychiatric disorders tend to do worse than patients without a psychiatric diagnosis when undergoing total hip arthroplasty (THA) or total knee arthroplasty (TKA). Whether this is due to their psychiatric condition, pharmacological treatment, a combination of the two, or something else has not been thoroughly analyzed-and there are no internationally accepted guidelines for perioperative management of psychiatric patients. This overview summarizes our current knowledge on perioperative risks in patients with preoperative psychiatric disorders and the possible role of psychotropic drugs in the perioperative course. This will be useful when planning future strategies for improvement of surgical outcome following hip and knee arthroplasty.
authors.affiliation: a Surgical Pathophysiology Section , Rigshospitalet , Copenhagen .|b Lundbeck Foundation Center for Fast-track Hip and Knee Arthroplasty .
authors.forename: Silas Hinsch
authors.initials: SH
authors.lastname: Gylvin
authors.affiliation: a Surgical Pathophysiology Section , Rigshospitalet , Copenhagen .|b Lundbeck Foundation Center for Fast-track Hip and Knee Arthroplasty .
authors.forename: Christoffer Calov
authors.initials: CC
authors.lastname: Jørgensen
authors.affiliation: c Neuropsychiatry Laboratory, Department of Neuroscience and Pharmacology , University of Copenhagen , Copenhagen .|d Psychiatric Center Copenhagen, University of Copenhagen , Copenhagen , Denmark.
authors.forename: Anders
authors.initials: A
authors.lastname: Fink-Jensen
authors.affiliation: a Surgical Pathophysiology Section , Rigshospitalet , Copenhagen .|b Lundbeck Foundation Center for Fast-track Hip and Knee Arthroplasty .
authors.forename: Henrik
authors.initials: H
authors.lastname: Kehlet
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D014943:Global Health; D006801:Humans; D015994:Incidence; D007902:Length of Stay; D015207:Osteoarthritis, Hip / Q000150:complications / Q000601:surgery*; D020370:Osteoarthritis, Knee / Q000150:complications / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology*; D011618:Psychotic Disorders / Q000150:complications*; D012307:Risk Factors