title: The impact of anxiety, seizure severity, executive dysfunction, subjectively perceived psychological deficits, and depression on social function in patients with epilepsy.
abstract: The impact of anxiety, seizure severity, executive dysfunction, subjectively perceived psychological deficits, and depression on social function in patients with epilepsy (PWE) was analyzed. A brief cognitive screening test (EpiTrack) and an estimation of the last 6 months' cumulative seizure severity (Chalfont seizure severity scale) were performed, and questionnaires on subjectively perceived cognitive deficits (c.I.-Skala), anxiety (State-Trait Anxiety Inventory, STAIX1 and STAIX2), depression (Self Rating Depression Scale, SDS), and social function (Soziale Aktivität Selbstbeurteilungsskala, SASS) were completed. Forty PWE (aged 41.8 years, SD 16; 24 female, 16 male) were analyzed. Thirty-eight point 5 percent had a score signifying depression in the SDS; 20% had a pathological result in at least one of the anxiety scores. The ANOVA revealed that only anxiety as a trait symptom (STAIX2) had a significant influence on social function apart from the other factors (p<0.004). Additionally there was a trend for a significant influence of depressive symptoms (SDS) on social functioning (p=0.093). Symptoms of anxiety impair the social function of patients with epilepsy apart from depression, cognitive function, and seizure severity. They should be taken into account in the treatment of patients with epilepsy.
authors.affiliation: Klinik und Poliklinik für Neurologie, Universitätsmedizin Rostock, Gehlsheimerstr. 20, 18147 Rostock, Germany. Electronic address: christina.kampf@med.uni-rostock.de.
authors.forename: Christina
authors.initials: C
authors.lastname: Kampf
authors.affiliation: Klinik und Poliklinik für Neurologie, Universitätsmedizin Rostock, Gehlsheimerstr. 20, 18147 Rostock, Germany. Electronic address: uwe.walter@med.uni-rostock.de.
authors.forename: Uwe
authors.initials: U
authors.lastname: Walter
authors.affiliation: Klinik und Poliklinik für Neurologie, Universitätsmedizin Rostock, Gehlsheimerstr. 20, 18147 Rostock, Germany; Klinik Lengg, Bleulerstr. 60, 8008 Zürich, Switzerland. Electronic address: johannes.roesche@med.uni-rostock.de.
authors.forename: Johannes
authors.initials: J
authors.lastname: Rösche
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000175:diagnosis* / Q000453:epidemiology / Q000523:psychology; D001008:Anxiety Disorders / Q000523:psychology; D003072:Cognition Disorders / Q000175:diagnosis* / Q000453:epidemiology / Q000209:etiology / Q000523:psychology; D003863:Depression / Q000453:epidemiology / Q000523:psychology*; D003866:Depressive Disorder / Q000523:psychology; D004827:Epilepsy / Q000150:complications* / Q000453:epidemiology / Q000523:psychology; D056344:Executive Function; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010465:Perception; D010555:Personality Inventory; D011446:Prospective Studies; D012640:Seizures / Q000453:epidemiology / Q000523:psychology*; D012720:Severity of Illness Index; D012917:Social Adjustment; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Anxiety; Depression; Social function