title: Synthesis of Novel C-Pivot Lariat 18-Crown-6 Ethers and their Efficient Purification.
abstract: The syntheses of various lariat ethers including several not previously reported and their efficient purification are presented. The synthesis route brings together reactions from a variety of previous works leading to a robust and generalized approach to these C-pivot lariats. The main steps are condensation of functionalized diols with pentaethylene glycol ditosylate in the presence of potassium as a templating cation. Purification of the final products was achieved without chromatography by extracting from an aqueous potassium hydroxide solution.
authors.affiliation: Department of Chemistry, Florida Atlantic University, 777 Glades Road, Boca Raton, Florida 33431, USA.
authors.forename: Susovan
authors.initials: S
authors.lastname: Jana
authors.affiliation: Department of Chemistry, Florida Atlantic University, 777 Glades Road, Boca Raton, Florida 33431, USA.
authors.forename: Vallabh
authors.initials: V
authors.lastname: Suresh
authors.affiliation: Department of Chemistry, Florida Atlantic University, 777 Glades Road, Boca Raton, Florida 33431, USA.
authors.forename: Salvatore D
authors.initials: SD
authors.lastname: Lepore
keywords: 18-crown-6; C-pivot lariat ethers; crown compounds; macrocyles; potassium hydroxide purification