title: Unprotected Left Main Disease: Indications and Optimal Strategies for Percutaneous Intervention.
abstract: Although the incidence of left main (LM) coronary artery disease is relatively low in patients undergoing routine angiography, it is a common presentation in patients with acute coronary syndromes. With the current interventional tools and techniques, percutaneous intervention for LM disease has become a viable alternative to the traditional coronary artery bypass grafting. Factors that contribute to the success and appropriateness of percutaneous intervention for LM disease include coronary anatomy and patient-specific factors such as left ventricular function. Multiple considerations should be taken into account prior to intervention, including hemodynamic support if necessary, intravascular imaging to guide therapy, and stent technique. This review provides an overview of the current body of literature to support the use of percutaneous intervention in LM disease and serves as guideline for the interventionalist approaching LM revascularization.
authors.affiliation: Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.|Division of Cardiovascular Medicine, Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA.|Division of Cardiovascular Medicine, Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA.
authors.forename: Sandeep M
authors.initials: SM
authors.lastname: Patel
authors.affiliation: Center for Interventional Vascular Therapy, Division of Cardiology, NY Presbyterian Hospital/Columbia University Medical Center, New York, NY, USA.
authors.forename: Manish A
authors.initials: MA
authors.lastname: Parikh
authors.affiliation: Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH, USA. Sahil.Parikh@UHhospitals.org.|Division of Cardiovascular Medicine, Harrington Heart and Vascular Institute, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH, 44106, USA. Sahil.Parikh@UHhospitals.org.
authors.forename: Sahil A
authors.initials: SA
authors.lastname: Parikh
keywords: Bifurcation stenting; Hemodynamic support; Percutaneous coronary intervention; Unprotected left main disease