title: Dodecaborate-Functionalized Anchor Dyes for Cyclodextrin-Based Indicator Displacement Applications.
abstract: A new type of water-soluble anchor dyes, that is, dyes which carry an auxiliary unit for strong binding to macrocyclic host molecules, has been synthesized. It consists of 7-nitrobenzofurazan (NBD) as a dye and the dodecaborate cluster (B12H11R) as a dianionic, globular, and purely inorganic anchoring group for cyclodextrins (Ka > 10(5) M(-1)). The synthesized dodecaborate-substituted dyes show marked changes in their photophysical properties (UV-vis and fluorescence) upon complexation with cyclodextrins (β-CD and γ-CD), such that the resulting host·dye complexes (1:1 stoichiometry) present sensitive reporter pairs for indicator displacement applications.
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University Bremen , Campus Ring 1, 28759 Bremen, Germany.
authors.forename: Khaleel I
authors.initials: KI
authors.lastname: Assaf
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University Bremen , Campus Ring 1, 28759 Bremen, Germany.
authors.forename: Olga
authors.initials: O
authors.lastname: Suckova
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University Bremen , Campus Ring 1, 28759 Bremen, Germany.
authors.forename: Nader
authors.initials: N
authors.lastname: Al Danaf
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University Bremen , Campus Ring 1, 28759 Bremen, Germany.
authors.forename: Victoria
authors.initials: V
authors.lastname: von Glasenapp
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University Bremen , Campus Ring 1, 28759 Bremen, Germany.
authors.forename: Detlef
authors.initials: D
authors.lastname: Gabel
authors.affiliation: Department of Life Sciences and Chemistry, Jacobs University Bremen , Campus Ring 1, 28759 Bremen, Germany.
authors.forename: Werner M
authors.initials: WM
authors.lastname: Nau
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D003505:Cyclodextrins / Q000737:chemistry*; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D015394:Molecular Structure; D010069:Oxadiazoles / Q000737:chemistry
chemical_list: D001896:Boron Compounds; D003505:Cyclodextrins; D005456:Fluorescent Dyes; D010069:Oxadiazoles; C119788:dodecaborate