title: Differences of prevalence of dyslipidemia and risk factors related to LDL-c in the patients with abnormal fasting glucose between Uygur and Han in Xinjiang.
abstract: OBJECTIVE
  To evaluate the incidence of dyslipidemia among Uygur and Han patients with impaired fasting glucose (IFG). To investigate the influence factors on LDL-c in this population.
  
  
  METHODS
  This cross-sectional study included a total of 4709 participants, consisting of Uygurs patients (n=2053) and Han patients (n=2656) from Xinjiang province, who were screened for diabetes mellitus. A stratified multistage sampling design was used to collect the participants. The influence factors on LDL-c were analyzed by Logistic regression analysis.
  
  
  RESULTS
  Among the IFG patients (n=1757), Uighur IFG group had a higher prevalence of dyslipidemia than that of Han IFG group, 99.8% vs. 63.7%, P<0.05. Similar trends were existed in the prevalence of hypercholesteremia, hypertriglyceridemia, high LDL-c and low HDL-c (all P<0.05). Among the Uighur groups, IFG group had higher dyslipidemia rate than that of euglycemia group (74%). However, there was no such difference in the Han groups. Logistic regression analysis revealed that risk factors associated with LDL-c were age, total cholesterol and 2 h postprandial blood glucose for the Uighur IFG patients. However, gender and total cholesterol were risk factors for Han IFG patients.
  
  
  CONCLUSIONS
  Uighur IFG patients had higher incidence of dyslipidemia than that of Han IFG patients. For Uyghur IFG patients, closing follow-up of total cholesterol and 2 h postprandial blood glucose were necessary. As to the Han IFG patients, we should pay more attention to male and total cholesterol in order to lower LDL-c levels. So, appropriately preventive and therapeutic measures should be chosen based on the characteristics of abnormal lipid profiles in different nationality.
authors.affiliation: The First Affiliated Hospital of Xinjiang Medical University Xinjiang, China.
authors.forename: Li
authors.initials: L
authors.lastname: Quan
authors.affiliation: Ankang Central Hospital, Jinzhou South Road, Hanbin District Ankang 725000, Shaanxi, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Hu
authors.affiliation: The Armed Police General Hospital Xinjiang, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: The First Affiliated Hospital of Xinjiang Medical University Xinjiang, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Jiang
keywords: IFG; LDL-c; Uygur; dyslipidemia; han nationality