title: Psychometric study of the European Portuguese version of the PedsQL 3.0 Cancer Module.
abstract: BACKGROUND
  Health-related quality of life (HRQoL) is an important outcome to assess the impact of cancer. This article examines the psychometric properties of the European Portuguese self-report version of the Pediatric Quality of Life Inventory™ Cancer Module (PedsQL™ 3.0 Cancer Module) in children and adolescents with cancer.
  
  
  METHODS
  The participants, 332 children/adolescents diagnosed with cancer (8-18 years old), completed measures to assess HRQoL (PedsQL™ 3.0 Cancer Module and DISABKIDS Chronic Generic Measure; DCGM-12) and anxiety (Revised Children's Manifest Anxiety Scale - second edition; RCMAS-2). A subsample (n = 52) completed the PedsQL™ 3.0 Cancer Module a second time following one-week. The pediatric oncologists completed the Intensity of Treatment Rating Scale 3.0 (ITR 3.0).
  
  
  RESULTS
  For the whole sample, the PedsQL™ 3.0 Cancer Module demonstrated good item discrimination (rs = .30 to .54). The confirmatory factor analysis testing the presence of eight first-order factors loading significantly in a second-order factor revealed an acceptable fit (CFI = .91; RMSEA = .05). The correlation of PedsQL™ 3.0 Cancer Module with DCGM-12 (rs = .17 to .58), and with RCMAS-2 (rs = -.16 to-.51) attested convergent validity. This inventory demonstrated minimally acceptable to very good internal consistency (αs = .65 to .87) and temporal stability (ICCs = .61 to .81).
  
  
  CONCLUSIONS
  These findings demonstrate that the European Portuguese self-report version of the PedsQL™ 3.0 Cancer Module is a valid and reliable instrument for assessing HRQoL in pediatric cancer.
authors.affiliation: Faculty of Psychology and Educational Sciences, University of Coimbra, Coimbra, Portugal. susanafernandessantos@gmail.com.
authors.forename: Susana
authors.initials: S
authors.lastname: Santos
authors.affiliation: Faculdade de Psicologia, Universidade de Lisboa, Lisbon, Portugal.
authors.forename: Carla
authors.initials: C
authors.lastname: Crespo
authors.affiliation: Faculty of Psychology and Educational Sciences, University of Coimbra, Coimbra, Portugal.
authors.forename: M Cristina
authors.initials: MC
authors.lastname: Canavarro
authors.affiliation: UICISA: E, Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal.
authors.forename: Ananda
authors.initials: A
authors.lastname: Fernandes
authors.affiliation: UICISA: E, Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal.
authors.forename: Luís
authors.initials: L
authors.lastname: Batalha
authors.affiliation: UICISA: E, Escola Superior de Enfermagem de Coimbra, Coimbra, Portugal.
authors.forename: Diana
authors.initials: D
authors.lastname: de Campos
authors.affiliation: Portuguese Institute of Oncology (IPO-Porto), Porto, Portugal.
authors.forename: Armando
authors.initials: A
authors.lastname: Pinto
mesh_terms: D000293:Adolescent; D002648:Child; D005163:Factor Analysis, Statistical; D005260:Female; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000523:psychology*; D011174:Portugal; D011594:Psychometrics / Q000295:instrumentation*; D011788:Quality of Life / Q000523:psychology*; D015203:Reproducibility of Results; D057566:Self Report; D012720:Severity of Illness Index