title: Psychiatric Symptoms Associated with Oocyte-Donation.
abstract: Oocyte-donation is generally safe but may exacerbate psychiatric symptoms in some women. In this prospective study 63 oocyte-donating women and, as a control group, 63 women providing their own oocytes for in vitro fertilization (in couples with male infertility) were evaluated pre- and post-ovulation-induction in regard to hypochondriasis, anxiety, social impairment, and depression. The mean hypochondriasis score for oocyte-donators was significantly lower than for women providing their own oocytes, prior to ovulation-induction (5.03 vs. 6.59). However, after ovulation-induction and oocyte retrieval this score rose to 6.66 among oocyte-donators, whereas it remained essentially unchanged among women providing their own oocytes (6.66). The mean anxiety score for oocyte-donating women also rose following this procedure, from 5.87 to 7.65. Depression scores for both groups remained similar, before and after the procedure. Results showed that at the beginning of the ARP donating women have the same conditions as own oocyte women regarding depression and anxiety but after the egg harvesting they would suffer more damages regarding hypochondriasis and anxiety aspects.
authors.affiliation: Reproductive Health Department, Nursing and Midwifery Care Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Hezarjerib Av., Isfahan, Iran. Kazemi@nm.mui.ac.ir.
authors.forename: Ashraf
authors.initials: A
authors.lastname: Kazemi
authors.affiliation: Reproductive Health Department, Student Research Center, School of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Maryam Zivari
authors.initials: MZ
authors.lastname: Delavar
authors.affiliation: Behavioral Sciences Research Center, Department of psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Kheirabadi
mesh_terms: D000328:Adult; D001007:Anxiety / Q000523:psychology*; D016022:Case-Control Studies; D003863:Depression / Q000523:psychology*; D005260:Female; D005307:Fertilization in Vitro; D006801:Humans; D006998:Hypochondriasis / Q000523:psychology*; D018587:Oocyte Donation / Q000523:psychology*; D054315:Oocyte Retrieval / Q000523:psychology*; D010062:Ovulation Induction / Q000523:psychology*; D011446:Prospective Studies; D012919:Social Behavior
keywords: Assisted Reproduction Program (ARP); Mental health; Oocyte-donor