title: Hair Follicle Miniaturization in a Woolly Hair Nevus: A Novel "Root" Perspective for a Mosaic Hair Disorder.
abstract: Woolly hair nevus is a mosaic disorder characterized by unruly, tightly curled hair in a circumscribed area of the scalp. This condition may be associated with epidermal nevi. We describe an 11-year-old boy who initially presented with multiple patches of woolly hair and with epidermal nevi on his left cheek and back. He had no nail, teeth, eye, or cardiac abnormalities. Analysis of plucked hairs from patches of woolly hair showed twisting of the hair shaft and an abnormal hair cuticle. Histopathology of a woolly hair patch showed diffuse hair follicle miniaturization with increased vellus hairs.
authors.affiliation: *St John's Institute of Dermatology, Guy's and St Thomas' NHS Trust, London, United Kingdom; †Department of Dermatology, Lewisham University Hospital, Lewisham, United Kingdom; ‡Centre for Ultrastructural Imaging, King's College London, London, United Kingdom; and §Department of Dermatopathology, St John's Institute of Dermatology, St Thomas' Hospital, London, United Kingdom.
authors.forename: Ophelia
authors.initials: O
authors.lastname: Veraitch
authors.forename: Alfonso
authors.initials: A
authors.lastname: Perez
authors.forename: Shamali R
authors.initials: SR
authors.lastname: Hoque
authors.forename: Gema
authors.initials: G
authors.lastname: Vizcay-Barrena
authors.forename: Roland A
authors.initials: RA
authors.lastname: Fleck
authors.forename: David A
authors.initials: DA
authors.lastname: Fenton
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Stefanato
mesh_terms: D002648:Child; D006201:Hair Diseases / Q000473:pathology*; D018859:Hair Follicle / Q000502:physiology* / Q000648:ultrastructure*; D006801:Humans; D008297:Male; D008855:Microscopy, Electron, Scanning; D009030:Mosaicism; D009506:Nevus / Q000473:pathology