title: Designer cantilevers for even more accurate quantitative measurements of biological systems with multifrequency AFM.
abstract: Multifrequency excitation/monitoring of cantilevers has made it possible both to achieve fast, relatively simple, nanometre-resolution quantitative mapping of mechanical of biological systems in solution using atomic force microscopy (AFM), and single molecule resolution detection by nanomechanical biosensors. A recent paper by Penedo et al [2015 Nanotechnology 26 485706] has made a significant contribution by developing simple methods to improve the signal to noise ratio in liquid environments, by selectively enhancing cantilever modes, which will lead to even more accurate quantitative measurements.
authors.affiliation: Oxford Martin Programme on Nanotechnology, Clarendon Laboratory, Physics Department, University of Oxford, Parks Road, Oxford, OX1 3PU, UK.
authors.forename: S
authors.initials: S
authors.lastname: Contera