title: The association between serum uric acid and metabolic syndrome among adolescents in northeast China.
abstract: OBJECTIVE
  Data about the association between serum uric acid and metabolic syndrome in healthy adolescents are sparse. This study examined this association and determined the optimal cutoffs for serum uric acid to predict metabolic syndrome among healthy adolescents.
  
  
  METHODS
  During 2010-2011, we conducted a cross-sectional study of 927 adolescents (53.0% boys) aged 11-16 years from junior and senior high schools in northeast China. All participants received a physical examination and gave venous blood samples.
  
  
  RESULTS
  Serum uric acid was positively associated with abdominal obesity, dyslipidemia and hypertension in boys and with abdominal obesity and dyslipidemia in girls. For those with hyperurecemia, the odds ratios (95% CI) for metabolic syndrome were 7.67 (95% CI, 2.58~22.78) for boys and 4.77 (95% CI, 1.01~22.60) for girls. SUA was a better predictor of metabolic syndrome than fasting glucose, though not as good as waist circumference.
  
  
  CONCLUSIONS
  Among adolescents in China, serum uric acid level may be a useful predictor of metabolic syndrome.
authors.affiliation: Department of Endocrinology, Shengjing Hospital of China Medical University Shenyang 110004, Liaoning Province, PR China.
authors.forename: Zi-Nan
authors.initials: ZN
authors.lastname: Wang
authors.affiliation: Department of Endocrinology, Shengjing Hospital of China Medical University Shenyang 110004, Liaoning Province, PR China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.affiliation: Liaoyang Diabetes Hospital Liaoyang 111000, Liaoning Province, PR China.
authors.forename: Ran-Hua
authors.initials: RH
authors.lastname: Jiang
authors.affiliation: Department of Endocrinology, Shengjing Hospital of China Medical UniversityShenyang 110004, Liaoning Province, PR China; The Liaoning Provincial Key Laboratory of Endocrine DiseasesShenyang 111000, Liaoning Province, PR China.
authors.forename: Ling
authors.initials: L
authors.lastname: Li
authors.affiliation: Liaoyang Diabetes Hospital Liaoyang 111000, Liaoning Province, PR China.
authors.forename: Xue
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Endocrinology, Shengjing Hospital of China Medical University Shenyang 110004, Liaoning Province, PR China.
authors.forename: Liang
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Endocrinology, Shengjing Hospital of China Medical University Shenyang 110004, Liaoning Province, PR China.
authors.forename: Cong
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Pediatrics, The First Affiliated Hospital of Dalian Medical University Dalian 116011, Liaoning Province, PR China.
authors.forename: Cong-Liang
authors.initials: CL
authors.lastname: Tian
keywords: Adolescents; metabolic syndrome; public health; uric acid