title: Pharmacologic Strategies for Treatment of Poisonings.
abstract: Poisoning is the leading cause of injury-related mortality in the United States. Data suggest that nonmedical use of pharmaceuticals is increasing, along with a proportional increase in subsequent adverse events. The widespread use of illegal drugs contributes to the challenge, because these drugs may produce a wide array of clinical presentations that warrant time-critical recognition and treatment. Common legal and illegal poisonings highlighting clinical presentations in terms of toxidromes as a means of categorically recognizing these emergencies is the focus of this article. To optimize outcomes for situations such as these, pharmacologic considerations are discussed and explored.
authors.affiliation: Loyola University Chicago, 2160 South First Avenue, Marcella Niehoff School of Nursing Building, Room 4500, Maywood, IL 60153, USA. Electronic address: robertsdnp@gmail.com.
authors.forename: Eric
authors.initials: E
authors.lastname: Roberts
authors.affiliation: Vanderbilt University School of Nursing, Nashville, TN, USA; Middle Tennessee School of Anesthesia, Madison, TN, USA; Vanderbilt University Medical Center - LifeFlight, Nashville, TN, USA; TeamHealth at Maury Regional Medical Center, Columbia, TN, USA.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Gooch
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D062787:Drug Overdose / Q000188:drug therapy*; D005260:Female; D006801:Humans; D013287:Illicit Drugs / Q000506:poisoning*; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000188:drug therapy* / Q000453:epidemiology; D017410:Practice Guidelines as Topic; D055553:Prescription Drugs / Q000506:poisoning*; D016896:Treatment Outcome; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D013287:Illicit Drugs; D055553:Prescription Drugs
keywords: Drug abuse; Overdoses; Street drugs; Toxicology; Toxidromes