title: Use of Platelet Preparations in Facial Rejuvenation and Wound Healing Remains Unproven.
abstract: There is growing interest in the use of platelet derivatives in facial aesthetic surgery and wound healing. Sclafani et al. have concluded from their review of the literature that the vast majority of studies show a significant and measurable effect on facial aesthetic outcomes with the use of these platelet preparations. We suggest that an alternative review of the same literature may well have produced a different set of conclusions.
  
  
  METHODS
  This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
authors.affiliation: University College London Medical School, Gower Street, Bloomsbury, London, WC1E 6BT, UK. william.kenworthy.11@ucl.ac.uk.
authors.forename: William
authors.initials: W
authors.lastname: Kenworthy
authors.affiliation: University College London Medical School, Gower Street, Bloomsbury, London, WC1E 6BT, UK.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Langridge
authors.affiliation: Wellington Hospital, London, UK.
authors.forename: Nakul
authors.initials: N
authors.lastname: Patel
authors.affiliation: Wellington Hospital, London, UK.|, 150 Harley Street, London, UK.
authors.forename: Norman
authors.initials: N
authors.lastname: Waterhouse
mesh_terms: D000818:Animals; D001792:Blood Platelets; D003357:Cosmetic Techniques; D005145:Face; D006801:Humans; D053657:Platelet-Rich Plasma; D012060:Rejuvenation; D014945:Wound Healing
keywords: Facial esthetics; Growth factors; Platelet gel; Platelet-rich fibrin; Platelet-rich fibrin matrix; Platelet-rich plasma; Platelets; Wound healing