title: Using the American College of Rheumatology (ACR) and Systemic Lupus International Collaborating Clinics (SLICC) criteria to determine the diagnosis of systemic lupus erythematosus (SLE) in patients with subacute cutaneous lupus erythematosus (SCLE).
abstract: BACKGROUND
  Approximately 50% of patients with subacute cutaneous lupus erythematosus (SCLE) meet criteria for systemic lupus erythematosus (SLE). The Systemic Lupus International Collaborating Clinics (SLICC) developed new SLE criteria to improve the American College of Rheumatology (ACR) criteria but the SLICC criteria have not been evaluated in patients with SCLE.
  
  
  OBJECTIVE
  We sought to determine how patients with SCLE/SLE meet the ACR and SLICC criteria to compare the 2 sets of criteria.
  
  
  METHODS
  This was a retrospective analysis of 107 patients with SCLE enrolled in a database at the University of Pennsylvania.
  
  
  RESULTS
  Patients with SCLE/SLE were more likely than those with only SCLE to have oral ulcers, positive anti-double-stranded DNA antibodies, and positive antinuclear antibody test findings using both sets of criteria. Patients with SCLE/SLE were also more likely to have low complement using the SLICC criteria. There was a statistically insignificant increase in individuals meeting the SLICC criteria.
  
  
  CONCLUSIONS
  Not all patients received comprehensive laboratory testing.
  
  
  CONCLUSIONS
  Most patients with SCLE who formally meet criteria for SLE do so based on the laboratory and mucocutaneous criteria. Neither the ACR nor SLICC criteria distinguish patients with SCLE and major internal disease from patients with SCLE without major internal disease.
authors.affiliation: Corporal Michael J. Crescenz Philadelphia Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Janice
authors.initials: J
authors.lastname: Tiao
authors.affiliation: Biostatistics and Epidemiology at the Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Rui
authors.initials: R
authors.lastname: Feng
authors.affiliation: Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Kasey
authors.initials: K
authors.lastname: Carr
authors.affiliation: Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania.
authors.forename: Joyce
authors.initials: J
authors.lastname: Okawa
authors.affiliation: Corporal Michael J. Crescenz Philadelphia Department of Veterans Affairs Medical Center, Philadelphia, Pennsylvania; Department of Dermatology, University of Pennsylvania, Philadelphia, Pennsylvania. Electronic address: werth@mail.med.upenn.edu.
authors.forename: Victoria P
authors.initials: VP
authors.lastname: Werth
mesh_terms: D000328:Adult; D000368:Aged; D000974:Antibodies, Antinuclear / Q000276:immunology*; D015331:Cohort Studies; D003299:Cooperative Behavior; D016208:Databases, Factual; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000145:classification* / Q000175:diagnosis / Q000276:immunology; D008180:Lupus Erythematosus, Systemic / Q000145:classification* / Q000175:diagnosis / Q000276:immunology; D008297:Male; D008875:Middle Aged; D017410:Practice Guidelines as Topic / Q000592:standards*; D012189:Retrospective Studies; D012219:Rheumatology / Q000592:standards; D018570:Risk Assessment; D012955:Societies, Medical / Q000592:standards
chemical_list: D000974:Antibodies, Antinuclear
keywords: American College of Rheumatology; Systemic Lupus International Collaborating Clinics; classification criteria; cutaneous lupus erythematosus; subacute cutaneous lupus erythematosus; systemic lupus erythematosus