title: Staphylococcus epidermidis Sets Things Right Again.
abstract: Commensal cutaneous bacteria are believed to play a role in skin homeostasis, possibly by counteracting the effects of pathogenic inflammation. In this issue, Xia et al. show that Staphylococcus epidermidis is involved in the regulation of Propionibacterium acnes-induced inflammation. Staphylococcal lipoteichoic acid induces miR-143, which in turn inhibits toll-like receptor 2 mRNA to decrease toll-like receptor 2 protein and consequently suppresses P. acnes-induced proinflammatory cytokines.
authors.affiliation: Department of Dermatology and Allergology, Technical University Munich, Munich, Germany.
authors.forename: Yuliya
authors.initials: Y
authors.lastname: Skabytska
authors.affiliation: Department of Dermatology and Allergology, Technical University Munich, Munich, Germany. Electronic address: tilo.biedermann@tum.de.
authors.forename: Tilo
authors.initials: T
authors.lastname: Biedermann
mesh_terms: D000818:Animals; D008070:Lipopolysaccharides / Q000494:pharmacology*; D035683:MicroRNAs / Q000235:genetics*; D011425:Propionibacterium acnes; D013212:Staphylococcus epidermidis; D013682:Teichoic Acids / Q000494:pharmacology*; D051195:Toll-Like Receptor 2 / Q000235:genetics*
chemical_list: D008070:Lipopolysaccharides; D035683:MicroRNAs; D013682:Teichoic Acids; D051195:Toll-Like Receptor 2