title: The contribution of surprise to the prediction based modulation of fMRI responses.
abstract: In recent years, several functional magnetic resonance imaging (fMRI) studies showed that correct stimulus predictions reduce the neural responses when compared to surprising events (Egner et al., 2010). Further, it has been shown that such fulfilled expectations enhance the magnitude of repetition suppression (RS, i.e. a decreased neuronal response after the repetition of a given stimulus) in face selective visual cortex as well (Summerfield et al., 2008). Current MEG and neuroimaging studies suggest that the underlying mechanisms of expectation effects are independent from these of RS (Grotheer and Kovács, 2015; Todorovic and Lange, 2012). However, it is not clear as of today how perceptual expectations modulate the neural responses: is the difference between correctly predicted and surprising stimuli due to a genuine response reduction for correctly predicted stimuli or is it due to an increased response for surprising stimuli? Therefore, here we used a modified version of the paradigm of Grotheer and Kovács (2015) to induce predictions independently from repetition probability by presenting pairs of faces (female, male or infant) that were either repeated or alternating. Orthogonally to this, predictions were manipulated by the gender of the first face within each pair so that it signaled high, low or equal probability of repetitions. An unpredicted, neutral condition with equal probabilities for alternating and repeated trials was used to identify the role of surprising and enhancing modulations. Similarly, to Grotheer and Kovács (2015), we found significant RS and significant expectation effect in the FFA. Importantly, we observed larger response for surprising events in comparison to the neutral and correctly predicted conditions for alternating trials. Altogether, these results emphasize the role of surprise in prediction effects.
authors.affiliation: Institute of Psychology, Friedrich-Schiller-University of Jena, 07737 Jena, Germany.
authors.forename: Catarina
authors.initials: C
authors.lastname: Amado
authors.affiliation: Brain Imaging Centre, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1111 Budapest, Hungary.
authors.forename: Petra
authors.initials: P
authors.lastname: Hermann
authors.affiliation: Department of Cognitive Science, Budapest University of Technology and Economics, 1111 Budapest, Hungary; Brain Imaging Centre, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1111 Budapest, Hungary.
authors.forename: Petra
authors.initials: P
authors.lastname: Kovács
authors.affiliation: Institute of Psychology, Friedrich-Schiller-University of Jena, 07737 Jena, Germany; DFG Research Unit Person Perception, Friedrich-Schiller-University of Jena, 07743 Jena, Germany.
authors.forename: Mareike
authors.initials: M
authors.lastname: Grotheer
authors.affiliation: Department of Cognitive Science, Budapest University of Technology and Economics, 1111 Budapest, Hungary; Brain Imaging Centre, Research Centre for Natural Sciences, Hungarian Academy of Sciences, 1111 Budapest, Hungary.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Vidnyánszky
authors.affiliation: Institute of Psychology, Friedrich-Schiller-University of Jena, 07737 Jena, Germany; DFG Research Unit Person Perception, Friedrich-Schiller-University of Jena, 07743 Jena, Germany. Electronic address: gyula.kovacs@uni-jena.de.
authors.forename: Gyula
authors.initials: G
authors.lastname: Kovács
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping; D002560:Cerebrovascular Circulation / Q000502:physiology; D000066499:Facial Recognition / Q000502:physiology*; D005260:Female; D007839:Functional Laterality; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009483:Neuropsychological Tests; D010100:Oxygen / Q000097:blood; D010775:Photic Stimulation / Q000379:methods; D055815:Young Adult
chemical_list: D010100:Oxygen
keywords: Expectation; Prediction; Repetition suppression; Surprise; fMRI adaptation