title: The Investigation of Plasma Glucagon-like Peptide-1 Levels in Newly Diagnosed Type 1 Diabetic Children.
abstract: OBJECTIVE
  To reveal the possible role of glucagon-like peptide-1 (GLP-1) in newly diagnosed Type 1 diabetic children.
  
  
  METHODS
  Twenty-five newly diagnosed children and 22 healthy children were included in the study.
  
  
  RESULTS
  In oral glucose tolerance tests, no correlation was observed between C-peptide and GLP-1 levels at 0 and 30 minutes, and plasma GLP-1 levels in both groups at 0 and 30 minutes were not statistically different.
  
  
  CONCLUSIONS
  Consequently, fasting and postprandial GLP-1 levels in newly diagnosed Type 1 diabetic children are not different from healthy children. Glucagon-like peptide-1 levels in newly diagnosed Type 1 diabetic children suggest that plasma GLP-1 levels do not have any role in the pathogenesis of Type 1 diabetes mellitus.
authors.affiliation: Department of Pediatrics, Cukurova University, Adana, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Uslu
authors.affiliation: Department of Pediatric Endocrinology, Cukurova University, Adana, Turkey. e-mail: fggurbuz@yahoo.com.
authors.forename: F
authors.initials: F
authors.lastname: Gurbuz
authors.affiliation: Department of Pediatric Endocrinology, Cukurova University, Adana, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Temiz
authors.affiliation: Department of Pediatric Endocrinology, Cukurova University, Adana, Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Yuksel
authors.affiliation: Department of Pediatric Endocrinology, Cukurova University, Adana, Turkey.
authors.forename: N
authors.initials: N
authors.lastname: Mungan
authors.affiliation: Department of Pediatric Endocrinology, Cukurova University, Adana, Turkey.
authors.forename: A K
authors.initials: AK
authors.lastname: Topaloglu
keywords: C-peptide; Children; Type 1 diabetes mellitus; glucagon-like peptide-1