title: [Sympathetic ophthalmia : Therapy with steroid-free immunosuppressant azathioprine].
abstract: This article describes the case of a 48-year-old male patient who presented with persistent inflammation and deterioration of vision to a best corrected visual acuity (BCVA) of 0.6 in the only functioning left eye. The right eye had suffered a severe penetrating ocular trauma 6 months prior to presentation. After diagnosis of a sympathetic ophthalmia a high dosage corticosteroid therapy was initiated. Due to intolerance with decompensating diabetes an immunosuppressive therapy with azathioprine was initiated. This therapy resulted in stable clinical findings with an increase in BCVA to 0.9.
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, Technische Universität München, Ismaningerstr. 22, 81675, München, Deutschland. kerstin.wand@mri.tum.de.
authors.forename: K
authors.initials: K
authors.lastname: Wand
authors.affiliation: Institut für Allgemeine Pathologie und Pathologische Anatomie der Technischen Universität München, Trogerstr. 18, 81675, München, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Straub
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, Technische Universität München, Ismaningerstr. 22, 81675, München, Deutschland.
authors.forename: C P
authors.initials: CP
authors.lastname: Lohmann
authors.affiliation: Klinik und Poliklinik für Augenheilkunde, Klinikum rechts der Isar, Technische Universität München, Ismaningerstr. 22, 81675, München, Deutschland.
authors.forename: C S
authors.initials: CS
authors.lastname: Mayer
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D001379:Azathioprine / Q000008:administration & dosage*; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged; D009879:Ophthalmia, Sympathetic / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D016896:Treatment Outcome; D014786:Vision Disorders / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D007166:Immunosuppressive Agents; D001379:Azathioprine
keywords: Azathioprine; Cortisone; Granulomatous inflammation; Immunosuppression; Uveitis