title: Correlation between transvaginal ultrasound measured endometrial thickness and histopathological findings in Turkish women with abnormal uterine bleeding.
abstract: OBJECTIVE
  The present study aims to determine how transvaginal ultrasonography and histopathological examination findings are correlated in a cohort of premenopausal and postmenopausal Turkish women with abnormal uterine bleeding.
  
  
  METHODS
  This is a retrospective review of 350 Turkish women who underwent transvaginal ultrasonography and suction curettage as a result of abnormal uterine bleeding.
  
  
  RESULTS
  Sonographic appearance of the endometrium was normal in 244 patients (69.7%), while homogeneous thickening was detected in 47 patients (13.4%) and cystic thickening in 21 patients (6.0%). A sonographic diagnosis of endometrial polyp was made in 38 patients (10.9%). Histopathological analysis of endometrial samplings revealed proliferative endometrium (36%), secretory endometrium (24.6%), decidualization (10.9%), endometrial polyp (8.3%), endometritis (6.8%), endometrial hyperplasia (4.6%), irregular shedding (3.7%), atrophic endometrium (3.1%), endometrial cancer (1.1%) and placental retention (0.9%). The sonographic and histopathological findings correlated significantly (χ(2) = 122 768, P = 0.001; r = 0.215, P = 0.001). Approximately 51% of the women with homogeneous endometrial thickening had proliferative endometrium. Only 44.7% of the women with ultrasonographically visualized endometrial polyps had histopathologically diagnosed endometrial polyps. Nearly 57% of the women with cystic endometrial thickening had proliferative endometrium.
  
  
  CONCLUSIONS
  If there is no facility for hysteroscopy or hysteroscopy-guided endometrial biopsy for women with abnormal uterine bleeding, transvaginal ultrasonography findings can be efficiently used to make a preliminary diagnosis and, thus, notify the pathologists.
authors.affiliation: Departments of Obstetrics and Gynecology, Kahramanmaras Sutcu Imam University Medical Faculty Hospital, Kahramanmaras, Turkey.
authors.forename: Alev
authors.initials: A
authors.lastname: Ozer
authors.affiliation: Department of Obstetrics and Gynecology, Pazarcik State Hospital, Kahramanmaras, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Ozer
authors.affiliation: Department of Obstetrics and Gynecology, Afyon Kocatepe University Medical Faculty Hospital, Afyonkarahisar, Turkey.
authors.forename: Mine
authors.initials: M
authors.lastname: Kanat-Pektas
mesh_terms: D000328:Adult; D044466:Asian People; D004717:Endometrium / Q000000981:diagnostic imaging* / Q000473:pathology*; D005260:Female; D006801:Humans; D008796:Metrorrhagia / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging*; D017698:Postmenopause; D017697:Premenopause; D012189:Retrospective Studies; D014421:Turkey; D014463:Ultrasonography / Q000379:methods*; D055815:Young Adult
keywords: abnormal uterine bleeding; histopathological examination; transvaginal ultrasonography