title: Magnifying endoscopy simple diagnostic algorithm for early gastric cancer (MESDA-G).
abstract: Gastric cancer is the third leading cause of cancer death worldwide. Early detection and accurate diagnosis of mucosal cancer is desirable in order to achieve decreased mortality; cause-specific survival of patients with early gastric cancer is reported to exceed 95%. Endoscopy is the functional modality to detect early cancer; however, the procedure is not definitive when using conventional white-light imaging. In contrast, magnifying narrow-band imaging (M-NBI), a novel endoscopic technology, is a powerful tool for characterizing gastric mucosal lesions because it can visualize the microvascular architecture and microsurface structure. To date, many reports on the diagnosis of early gastric cancer by M-NBI, including multicenter prospective randomized studies conducted in Japan, have been published in peer-reviewed international journals. Based on these published data, we devised a proposal for a diagnostic strategy for gastric mucosal cancer using M-NBI to simplify the process of diagnosis and improve accuracy. Herein, we recommend a diagnostic algorithm for early gastric cancer using magnifying endoscopy.
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Muto
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Kenshi
authors.initials: K
authors.lastname: Yao
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Kaise
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Mototsugu
authors.initials: M
authors.lastname: Kato
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Noriya
authors.initials: N
authors.lastname: Uedo
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Yagi
authors.affiliation: The Japanese Gastroenterological Association, Tokyo, Japan.|Japan Gastroenterological Endoscopy Society, Tokyo, Japan.|The Japanese Gastric Cancer Association, Kyoto, Japan.
authors.forename: Hisao
authors.initials: H
authors.lastname: Tajiri
mesh_terms: D000465:Algorithms; D055088:Early Detection of Cancer; D005773:Gastroscopy; D006801:Humans; D007564:Japan; D011446:Prospective Studies; D016032:Randomized Controlled Trials as Topic; D013274:Stomach Neoplasms / Q000175:diagnosis*
keywords: diagnosis; early cancer; gastric cancer; magnifying endoscopy; narrow-band imaging