title: Image contrast reduction mechanism in full-field optical coherence tomography.
abstract: Correct interpretation of image contrast obtained with full-field optical coherence tomography (FFOCT) technique is required for accurate medical diagnosis applications. In this work, first, the characteristics of microscopic structures of tissue that generate the contrast in en-face tomographic image obtained with FFOCT are discussed. Then an overview is given of the parameters that affect image contrast. Finally, the contrast correction factor for correct image interpretation and the contrast limits to practical FFOCT systems are outlined.
authors.affiliation: Department of Optical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu, P. R. China.
authors.forename: Wanrong
authors.initials: W
authors.lastname: Gao
mesh_terms: D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D012031:Refractometry; D059629:Signal-To-Noise Ratio; D041623:Tomography, Optical Coherence / Q000295:instrumentation / Q000379:methods*
keywords: Coherence; full-field optical coherence tomography; image contrast; multiply scattered background