title: The Clinical Effects of Dai-kenchu-to on Postoperative Intestinal Movement and Inflammatory Reaction in Colorectal Surgery.
abstract: OBJECTIVE
  We analyzed the effects of the Kampo medicine "Dai-kenchu-to" (DKT) on clinical aspects in colorectal surgery.
  
  
  METHODS
  Total 122 patients who underwent colorectal cancer surgery were divided into a DKT group (n = 53) and a non-DKT group (n = 69). The differences of postoperative course and anti-inflammatory responses between those two groups were analyzed.
  
  
  RESULTS
  The 53 out of 59 patients could completely take DKT. In the postoperative course, significant difference was observed in the first flatus day. In the anti-inflammatory effects, differences were observed in the heart rate (HR) of the 3rd POD. In the change between 1st POD and 3rd POD, HR in the DKT group was well controlled compared to the non-DKT group. In the patients who had over 37.5°C of body temperature in 1st POD (n = 53), inflammatory response of the DKT group was reduced compared to the non-DKT group.
  
  
  CONCLUSIONS
  The DKT might have the favorable influences on postoperative bowel movement and systemic inflammatory reaction, and induce the better postoperative course.
authors.forename: Gakuji
authors.initials: G
authors.lastname: Osawa
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Yoshimatsu
authors.forename: Hajime
authors.initials: H
authors.lastname: Yokomizo
authors.forename: Taisuke
authors.initials: T
authors.lastname: Otani
authors.forename: Atsuo
authors.initials: A
authors.lastname: Matsumoto
authors.forename: Mao
authors.initials: M
authors.lastname: Nakayama
authors.forename: Kenji
authors.initials: K
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D016022:Case-Control Studies; D015179:Colorectal Neoplasms / Q000601:surgery*; D003672:Defecation; D013505:Digestive System Surgical Procedures; D005260:Female; D005334:Fever / Q000453:epidemiology*; D005414:Flatulence; D006339:Heart Rate; D006801:Humans; D045823:Ileus / Q000453:epidemiology*; D007249:Inflammation / Q000453:epidemiology; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D005894:Panax; D010936:Plant Extracts / Q000627:therapeutic use*; D011183:Postoperative Complications / Q000453:epidemiology*; D032106:Zanthoxylum; D030521:Zingiberaceae
chemical_list: D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; C121414:dai-kenchu-to