title: Sterols and Fatty Acids of the Harmful Dinoflagellate Cochlodinium polykrikoides.
abstract: Sterol and fatty acid compositions were determined for Cochlodinium polykrikoides, a toxic, bloom-forming dinoflagellate of global significance. The major sterols were dinosterol (40% of total sterols), dihydrodinosterol (32%), and the rare 4α-methyl Δ(8(14)) sterol, amphisterol (23%). A minor sterol, 4α-methylergost-24(28)-enol was also detected (5.0%). The fatty acids had a high proportion of PUFAs (47%), consisting mainly of EPA (20%) and the relatively uncommon octadecapentaenoic acid (18 : 5, 22%). While unlikely to be responsible for toxicity to fish, these lipids may contribute to the deleterious effects of this alga to invertebrates.
authors.affiliation: Department of Chemistry, State University of New York - ESF, Syracuse NY 13210, USA, (phone: +1-315-470-6895; fax: +1-315-470-6856). jlginer@syr.edu.
authors.forename: José-Luis
authors.initials: JL
authors.lastname: Giner
authors.affiliation: Department of Chemistry, State University of New York - ESF, Syracuse NY 13210, USA, (phone: +1-315-470-6895; fax: +1-315-470-6856).
authors.forename: Harriette
authors.initials: H
authors.lastname: Ceballos
authors.affiliation: Key Laboratory of Marine Ecology and Environmental Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266071, P. R. China.|School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
authors.forename: Ying-Zhong
authors.initials: YZ
authors.lastname: Tang
authors.affiliation: School of Marine and Atmospheric Sciences, Stony Brook University, Stony Brook, NY 11794, USA.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Gobler
mesh_terms: D004141:Dinoflagellida / Q000737:chemistry*; D005227:Fatty Acids / Q000032:analysis*; D005231:Fatty Acids, Unsaturated / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D013261:Sterols / Q000032:analysis*
chemical_list: D005227:Fatty Acids; D005231:Fatty Acids, Unsaturated; D013261:Sterols
keywords: Chemotaxonomy; Fatty acids; Marine natural products; Marine sterols