title: We still go for the jugular: implications of the 3SITES central venous catheter study for nephrology.
abstract: The 3SITES study randomly assigned a nontunneled central venous catheter site in over 3000 adults treated in intensive care units. The subclavian site was associated with a lower rate of short-term complications, including catheter-related bloodstream infection and deep venous thrombosis, compared to the femoral or internal jugular site. Nephrologists should be aware of this study and should continue to advocate for alternatives to subclavian vein catheter placement in patients with chronic kidney disease who are expected to require arteriovenous access for dialysis in the future.
authors.affiliation: Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: christina.wyatt@mssm.edu.
authors.forename: Christina M
authors.initials: CM
authors.lastname: Wyatt
authors.affiliation: Icahn School of Medicine at Mount Sinai, New York, New York, USA; National Kidney Foundation Inc., New York, New York, USA.
authors.forename: Joseph A
authors.initials: JA
authors.lastname: Vassalotti
mesh_terms: D001166:Arteriovenous Shunt, Surgical / Q000009:adverse effects; D055499:Catheter-Related Infections / Q000209:etiology; D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D002408:Catheters, Indwelling / Q000009:adverse effects; D062905:Central Venous Catheters / Q000009:adverse effects; D005268:Femoral Vein; D006801:Humans; D007601:Jugular Veins; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic; D006435:Renal Dialysis / Q000009:adverse effects; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis / Q000628:therapy*; D018570:Risk Assessment; D012307:Risk Factors; D013350:Subclavian Vein; D020246:Venous Thrombosis / Q000209:etiology