title: "AVOID"ing harm by a double-edged sword: is there a role for ultrafiltration in heart failure?
abstract: Prior studies comparing ultrafiltration with medical management for acute decompensated heart failure have yielded conflicting results. The AVOID-HF trial was designed as a definitive comparison of optimal ultrafiltration versus optimal diuretic-based medical therapy; unfortunately, the trial was terminated prematurely because of slow recruitment. The results of AVOID-HF nevertheless provide a rationale for well-designed, adequately powered trials to determine whether ultrafiltration has a role in the routine management of acute decompensated heart failure.
authors.affiliation: Division of Nephrology, Hypertension, and Renal Transplantation, University of Florida, Gainesville, Florida, USA. Electronic address: amir.kazory@medicine.ufl.edu.
authors.forename: Amir
authors.initials: A
authors.lastname: Kazory
mesh_terms: D004232:Diuretics / Q000627:therapeutic use*; D057239:Early Termination of Clinical Trials; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D018579:Patient Selection; D016032:Randomized Controlled Trials as Topic; D018570:Risk Assessment; D012307:Risk Factors; D018401:Sample Size; D016896:Treatment Outcome; D014462:Ultrafiltration / Q000009:adverse effects*
chemical_list: D004232:Diuretics