title: Tandem Copper-Catalyzed Propargylation/Alkyne Azacyclization/Isomerization Reaction under Microwave Irradiation: Synthesis of Fully Substituted Pyrroles.
abstract: A copper-catalyzed and microwave-assisted synthesis of fully substituted pyrroles has been developed. A series of pentasubstituted pyrroles, especially α-arylpyrroles, could be obtained in moderate to good yields (up to 93%) through a tandem propargylation/alkyne azacyclization/isomerization sequence from readily available β-enamino compounds and propargyl acetates.
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.|Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry and Life Science, Zhejiang Normal University , Jinhua 321004, P. R. China.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Zhang
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Zhi-Wei
authors.initials: ZW
authors.lastname: Yang
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Zhongzhu
authors.initials: Z
authors.lastname: Chen
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Dong-Lin
authors.initials: DL
authors.lastname: Yang
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Ze
authors.initials: Z
authors.lastname: Shen
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Hu
authors.affiliation: Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry and Life Science, Zhejiang Normal University , Jinhua 321004, P. R. China.
authors.forename: Jian-Wu
authors.initials: JW
authors.lastname: Xie
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Jin
authors.initials: J
authors.lastname: Zhang
authors.affiliation: International Academy of Targeted Therapeutics and Innovation, Chongqing University of Arts and Sciences , 319 Honghe Ave., Yongchuan, Chongqing 402160, P. R. China.
authors.forename: Hai-Lei
authors.initials: HL
authors.lastname: Cui