title: Inflammatory Myofibroblastic Tumor of the Larynx:A Case Report.
abstract: BACKGROUND
  Inflammatory myofibroblastic pseudotumors are initially described in the lung and various extrapulmonary sites such as the orbits, palatine tonsils, ears, gingiva, pterygomaxillary space, and periodontal tissues. These tumors rarely involve the larynx and predilection to the glottis occurs in an indolent manner.
  
  
  METHODS
  This case describes a laryngeal myofibroblastic tumor in a 46-year-old woman who presented with an aggressive tumor that extended to the floor of the mouth and the base of the tongue. Extended supraglottic laryngectomy was undertaken for the patient. The diagnosis was spindle cell proliferation with dense lymphoplasma cell infiltration compatible with inflammatory myofibroblastic tumor (Inflammatory pseudotumor or plasma cell granuloma). Definitive diagnosis was achieved with immunohistochemical (IHC) staining.
  
  
  CONCLUSIONS
  We believe that further IHC studies are required to define the true nature of these tumors especially for those that behave in an aggressive pattern.
authors.affiliation: Department of Otorhinolaryngology, Hazart Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Farzad
authors.initials: F
authors.lastname: Izadi
authors.affiliation: ENT & HNS Research Center, Hazart Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Hadi
authors.initials: H
authors.lastname: Ghanbari
authors.affiliation: Pathologist, Shahriyar Hospital, Tehran, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Azizi
authors.affiliation: Department of Otorhinolaryngology, Hazart Rasoul Akram Hospital, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Shahram
authors.initials: S
authors.lastname: Gasembaglou
authors.affiliation: General Practitioner, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad Javad
authors.initials: MJ
authors.lastname: Manteghi
authors.affiliation: College of Dentistry, Ajman University of Science and Technology, Ajman, UAE.
authors.forename: Azadeh
authors.initials: A
authors.lastname: Ghanbari
keywords: Head and neck tumor; Immunohistochemstry (IHC); Inflammatory myofibroblastic tumor; Laryngeal mass.; laryngeal pseudotumor; larynx