title: [Application of anaerobic bacteria detection in oral and maxillofacial infection].
abstract: OBJECTIVE
  To investigate the distribution and drug resistance of anaerobic bacteria in the patients with oral and maxillofacial infection.
  
  
  METHODS
  Aerobic and anaerobic bacteria cultures from 61 specimens of pus from the patients with oral and maxillofacial infection in the Department of Oral and Maxillofacial Surgery, Peking University School of Stomatology were identified. The culture type was evaluated by API 20A kit and drug resistance test was performed by Etest method. The clinical data and antibacterial agents for the treatment of the 61 cases were collected, and the final outcomes were recorded.
  
  
  RESULTS
  The bacteria cultures were isolated from all the specimens, with aerobic bacteria only in 6 cases (9.8%), anaerobic bacteria only in 7 cases (11.5%), and both aerobic and anaerobic bacteria in 48 cases (78.7%). There were 55 infected cases (90.2%) with anaerobic bacteria, and 81 anaerobic bacteria stains were isolated. The highest bacteria isolation rate of Gram positive anaerobic bacteria could be found in Peptostreptococcus, Bifidobacterium and Pemphigus propionibacterium. No cefoxitin, amoxicillin/carat acid resistant strain was detected in the above three Gram positive anaerobic bacteria. The highest bacteria isolation rate of Gram negative anaerobic bacteria could be detected in Porphyromonas and Prevotella. No metronidazole, cefoxitin, amoxicillin/carat acid resistant strain was found in the two Gram negative anaerobic bacteria. In the study, 48 patients with oral and maxillofacial infection were treated according to the results of drug resistance testing, and the clinical cure rate was 81.3%.
  
  
  CONCLUSIONS
  Mixed aerobic and anaerobic bacteria cultures are very common in most oral and maxillofacial infection patients. Anaerobic bacteria culture and drug resistance testing play an important role in clinical treatment.
authors.affiliation: Department of Clinical Laboratory, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Zhen-ying
authors.initials: ZY
authors.lastname: Bao
authors.affiliation: Department of Clinical Laboratory, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Lin
authors.affiliation: Department of Clinical Laboratory, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Yan-hong
authors.initials: YH
authors.lastname: Meng
authors.affiliation: Department of Clinical Laboratory, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Chun
authors.initials: C
authors.lastname: He
authors.affiliation: Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Jia-zeng
authors.initials: JZ
authors.lastname: Su
authors.affiliation: Department of Oral and Maxillofacial Surgery, Peking University School and Hospital of Stomatology, Beijing 100081, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Peng
mesh_terms: D000658:Amoxicillin / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001421:Bacteria, Anaerobic / Q000187:drug effects / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000175:diagnosis*; D000068476:Beijing; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D006801:Humans; D008795:Metronidazole / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D009055:Mouth / Q000382:microbiology* / Q000473:pathology
chemical_list: D000900:Anti-Bacterial Agents; D008795:Metronidazole; D000658:Amoxicillin