title: Selective and Sensitive Detection of Cyanide Based on the Displacement Strategy Using a Water-Soluble Fluorescent Probe.
abstract: A water-soluble fluorescent probe (C-GGH) was used for the highly sensitive and selective detection of cyanide (CN(-)) in aqueous media based on the displacement strategy. Due to the presence of the recognition unit GGH (Gly-Gly-His), the probe C-GGH can coordinate with Cu(2+) and consequently display ON-OFF type fluorescence response. Furthermore, the in situ formed nonfluorescent C-GGH-Cu(2+) complex can act as an effective OFF-ON type fluorescent probe for sensing CN(-) anion. Due to the strong binding affinity of CN(-) to Cu(2+), CN(-) can extract Cu(2+) from C-GGH-Cu(2+) complex, leading to the release of C-GGH and the recovery of fluorescent emission of the system. The probe C-GGH-Cu(2+) allowed detection of CN(-) in aqueous solution with a LOD (limit of detection) of 0.017 μmol/L which is much lower than the maximum contaminant level (1.9 μmol/L) for CN(-) in drinking water set by the WHO (World Health Organization). The probe also displayed excellent specificity for CN(-) towards other anions, including F(-), Cl(-), Br(-), I(-), SCN(-), PO4 (3-), N3 (-), NO3 (-), AcO(-), SO4 (2-), and CO3 (2-).
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450000, China; College of Chemistry and Chemical Engineering, Pingdingshan University, Pingdingshan, Henan 467000, China.
authors.forename: Ming
authors.initials: M
authors.lastname: La
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
authors.forename: Yuanqiang
authors.initials: Y
authors.lastname: Hao
authors.affiliation: Changjun Middle School of Changsha, Changsha 410002, China.
authors.forename: Zhaoyang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: School of Life and Environmental Sciences, Guilin University of Electronic Technology, Guilin 541004, China.
authors.forename: Guo-Cheng
authors.initials: GC
authors.lastname: Han
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450000, China.
authors.forename: Lingbo
authors.initials: L
authors.lastname: Qu