title: How ovarian transplantation works and how resting follicle recruitment occurs: a review of results reported from one center.
abstract: Ovarian freezing and transplantation has garnered increasing interest as a potential way of preserving fertility in cancer patients. This special report aims to identify the success rate of frozen compared with fresh ovarian cortex transplantation (in one single series from one center for the sake of consistency), as well as potentially provides insight into the mechanism behind ovarian follicle recruitment. A comparison of fresh versus frozen transplantation techniques is presented, highlighting the similarity and differences between the fresh and frozen transplantation procedures. Much of the literature is scattered case reports with different patient populations and different techniques. This represents an effort to simplify and popularize an approach that has yielded favorable results (all cases recovered ovulation and 75% had successful spontaneous pregnancy) in one single, disciplined study.
authors.affiliation: Infertility Center of St. Louis, 224 S. Woods Mill Road, Suite 730, St. Louis, MO 63017, USA.|Department of Obstetrics & Gynecology, University of Amsterdam, 1012 WX Amsterdam, The Netherlands.|Sun Yat-Sen Medical School, No.74 Zhongshan Rd.2, Guangzhou, P.R. China.
authors.forename: Sherman
authors.initials: S
authors.lastname: Silber
mesh_terms: D000328:Adult; D015925:Cryopreservation; D005260:Female; D059247:Fertility Preservation / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D006080:Ovarian Follicle / Q000637:transplantation*
keywords: fertility; follicle recruitment; ovarian freezing; preservation; transplant