title: Enantioselective additions of copper acetylides to cyclic iminium and oxocarbenium ions.
abstract: The development of enantioselective, copper-catalyzed alkynylations of cyclic iminium and oxocarbenium ions is reviewed. The use of chiral copper-based catalysts has enabled high yields and enantioselectivites in the formation of nitrogen- and oxygen-containing heterocycles with α-stereogenic centers. This review highlights both the accomplishments and the future work needed in this important area.
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.
authors.forename: Jixin
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.
authors.forename: Srimoyee
authors.initials: S
authors.lastname: Dasgupta
authors.affiliation: Department of Chemistry and Biochemistry, University of Delaware, Newark, DE 19716, USA.
authors.forename: Mary P
authors.initials: MP
authors.lastname: Watson
keywords: catalysis; copper; enantioselectivity; iminium ion; oxocarbenium ion