title: Chordoid glioma of the third ventricle: a patient presenting with SIADH and a review of this rare tumor.
abstract: BACKGROUND
  Chordoid glioma of the third ventricle is a rare and recently described tumor characterized by a unique histomorphology and exclusive association with the suprasellar/third ventricular compartment. Its clinical, radiological and histological features may vary. Despite the fact that chordoid glioma is a low-grade tumor, its prognosis has been relatively poor because of its insidious presentation and the difficulty in obtaining complete surgical resection.
  
  
  METHODS
  Here, we report on a new case of chordoid glioma occurring in a 48-year-old woman, presented with hyponatremia, and on the initial work-up with a diagnosis of hyponatremia due at least in part to SIADH. We review the current literature on this rare pathology, discuss the radiological and histopathologic findings, and discuss the optimal management of chordoid glioma in general.
  
  
  CONCLUSIONS
  Based on this new case and the previous literature reports, we suggest that chordoid glioma should be included in the differential diagnosis of uncommon masses of the third ventricle, especially in middle-aged women, and we emphasize current management guidelines.
authors.affiliation: Department of Endocrinology, OCDEM, Churchill Hospital Oxford, Oxford, UK. matimat79@gmail.com.|Endocrinology Unit, Department of Systems Medicine, S. Eugenio and CTO A. Alesini Hospitals, University Tor Vergata, Rome, Italy. matimat79@gmail.com.
authors.forename: Matilde
authors.initials: M
authors.lastname: Calanchini
authors.affiliation: Department of Neurosurgery, John Radcliffe Hospital, Oxford, UK.
authors.forename: Simon
authors.initials: S
authors.lastname: Cudlip
authors.affiliation: Department of Neuropathology, John Radcliffe Hospital, Oxford, UK.
authors.forename: Monika
authors.initials: M
authors.lastname: Hofer
authors.affiliation: Department of Radiology, Churchill Hospital Oxford, Oxford, UK.
authors.forename: James
authors.initials: J
authors.lastname: Byrne
authors.affiliation: Endocrinology Unit, Department of Systems Medicine, S. Eugenio and CTO A. Alesini Hospitals, University Tor Vergata, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Fabbri
authors.affiliation: Department of Endocrinology, OCDEM, Churchill Hospital Oxford, Oxford, UK.
authors.forename: Ashley
authors.initials: A
authors.lastname: Grossman
mesh_terms: D002551:Cerebral Ventricle Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D005260:Female; D005910:Glioma / Q000150:complications* / Q000473:pathology; D006801:Humans; D007177:Inappropriate ADH Syndrome / Q000209:etiology*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D035583:Rare Diseases / Q000150:complications / Q000473:pathology; D020542:Third Ventricle / Q000000981:diagnostic imaging / Q000601:surgery
keywords: Chordoid glioma; Chordoid glioma of the third ventricle; Inappropriate ADH syndrome; SIADH