title: Peritoneal mesothelioma metastasis to the tongue - Comparison with 8 pleural mesothelioma reports with tongue metastases.
abstract: OBJECTIVE
  Malignant mesothelioma (MM) rarely arises from the peritoneum. We describe the 1st such case which metastasised to the head and neck region (tongue).
  
  
  METHODS
  We briefly surveyed the American Surveillance Epidemiology and End Results (SEER) database, and the British Cancer Research UK database for the latest trends in MM incidence. We did a systematic Pubmed search for other MM reports with tongue metastases.
  American and British data show that MM incidence in men has stabilised in the last 10 years, earlier than previously predicted. The tongue is an unusual site for MM spread, with ours being only the 9th such case described. Our summary of published cases of MM metastasising to the tongue brings out our patient to be the least in age(35 years), and the only one to have peritoneal MM as the primary. Seven of the 9 cases were male. Only 2 had a recorded history of exposure to asbestos. All 9 patients had the epithelioid subtype of MM. Surgery was done as the exclusive reported intervention in 4 out of the 9 patients. Only 2 cases received radiotherapy, amongst whom, only our patient responded.
  
  
  CONCLUSIONS
  Metastasis of MM to the tongue is rare and usually in the uncommon context of MM with multiple sites of extra-thoracic or extra-abdominal spread. We have described a unique clinical manifestation of a rare subtype of mesothelioma. Moreover, we have tabulated and summarised details (including responses to surgery or/and radiotherapy) regarding all reported cases of mesotheliomas with tongue metastasis.
authors.affiliation: Department of Radiation Oncology, The Canberra Hospital, Canberra, ACT, Australia.
authors.forename: Melisa V
authors.initials: MV
authors.lastname: Vazquez
authors.affiliation: Department of Surgery, Westmead Hospital, Westmead, NSW, Australia.
authors.forename: Selwyn
authors.initials: S
authors.lastname: Selvendran
authors.affiliation: Department of Medicine, St George Clinical School, University of New South Wales, Sydney, NSW, Australia.
authors.forename: Rajkumar
authors.initials: R
authors.lastname: Cheluvappa
authors.affiliation: North Coast Cancer Institute, Lismore Base Hospital, Lismore, NSW, Australia.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: McKay
keywords: CT, Computerised tomography; Gy, Gray; HIPEC, Hyperthermic intraperitoneal chemotherapy; MM, Malignant mesothelioma; MRI, Magnetic resonance imaging; Malignant mesothelioma; PET, Positron emission tomography; Peritoneal mesothelioma; Pleural mesothelioma; RX, Recipe (Treatment); Radiotherapy; SEER, Surveillance epidemiology and end results; Surgery; Tongue metastasis; cm, Centimetre (s); mm, millimetre