title: Risk factors for anastomotic dehiscence in colon cancer surgery--a population-based registry study.
abstract: OBJECTIVE
  The aim of this was to assess potential risk factors for anastomotic dehiscence in colon cancer surgery in a national cohort.
  
  
  METHODS
  All patients, who had undergone a resection of a large bowel segment with an anastomosis between 2008 and 2011, were identified in the Swedish Colon Cancer Registry. Patient factors, socioeconomic factors, surgical factors, and medication and hospital data were combined to evaluate risk factors for anastomotic dehiscence.
  
  
  RESULTS
  The prevalence of anastomotic dehiscence was 4.3 % (497/11 565). Male sex, ASA classification III-IV, prescribed medications, bleeding more than 300 mL, and uncommon colorectal resections were associated with a higher risk of anastomotic dehiscence. Hospital stay was increased with 14.5 days, and 30-day mortality as well as long-term mortality was higher in the anastomotic dehiscence group.
  
  
  CONCLUSIONS
  There are several factors that are possible to know preoperatively or during surgery that can indicate whether an anastomosis is an appropriate option. Anastomotic dehiscence increases hospital stay and long-term mortality.
authors.affiliation: Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden. bodil.gessler@vgregion.se.|SSORG-Scandinavian Surgical Outcomes Research Group, Gothenburg, Sweden. bodil.gessler@vgregion.se.
authors.forename: Bodil
authors.initials: B
authors.lastname: Gessler
authors.affiliation: Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden.|SSORG-Scandinavian Surgical Outcomes Research Group, Gothenburg, Sweden.
authors.forename: David
authors.initials: D
authors.lastname: Bock
authors.affiliation: SSORG-Scandinavian Surgical Outcomes Research Group, Gothenburg, Sweden.|Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730, Herlev, Denmark.
authors.forename: Hans-Christian
authors.initials: HC
authors.lastname: Pommergaard
authors.affiliation: SSORG-Scandinavian Surgical Outcomes Research Group, Gothenburg, Sweden.|Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730, Herlev, Denmark.
authors.forename: Jakob
authors.initials: J
authors.lastname: Burcharth
authors.affiliation: SSORG-Scandinavian Surgical Outcomes Research Group, Gothenburg, Sweden.|Department of Surgery, Herlev Hospital, University of Copenhagen, Herlev Ringvej 75, DK-2730, Herlev, Denmark.
authors.forename: Jacob
authors.initials: J
authors.lastname: Rosenberg
authors.affiliation: Department of Surgery, Institute of Clinical Sciences, Sahlgrenska Academy at University of Gothenburg, Sahlgrenska University Hospital/Östra, SE-416 85, Gothenburg, Sweden.|SSORG-Scandinavian Surgical Outcomes Research Group, Gothenburg, Sweden.
authors.forename: Eva
authors.initials: E
authors.lastname: Angenete
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000714:Anastomosis, Surgical; D003110:Colonic Neoplasms / Q000401:mortality / Q000601:surgery*; D005260:Female; D006761:Hospitals; D006801:Humans; D007902:Length of Stay; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011300:Preoperative Care; D012042:Registries; D012307:Risk Factors; D012959:Socioeconomic Factors; D013529:Surgical Wound Dehiscence / Q000453:epidemiology* / Q000209:etiology*; D055815:Young Adult
keywords: Anastomotic dehiscence; Colon cancer; Colorectal surgery; National audit; Risk factors