title: Gender Differences in HIV Sexual Risk Behaviors Among Clients of Substance Use Disorder Treatment Programs in the U.S.
abstract: This study examined differences in sexual risk behaviors by gender and over time among 1281 patients (777 males and 504 females) from 12 community-based substance use disorder treatment programs throughout the United States participating in CTN-0032, a randomized control trial conducted within the National Drug Abuse Treatment Clinical Trials Network. Zero-inflated negative binomial and negative binomial models were used in the statistical analysis. Results indicated significant reductions in most types of sexual risk behaviors among substance users regardless of the intervention arms. There were also significant gender differences in sexual risk behaviors. Men (compared with women) reported more condomless sex acts with their non-primary partners (IRR = 1.80, 95 % CI 1.21-2.69) and condomless anal sex acts (IRR = 1.74, 95 % CI 1.11-2.72), but fewer condomless sex partners (IRR = 0.87, 95 % CI 0.77-0.99), condomless vaginal sex acts (IRR = 0.83, 95 % CI 0.69-1.00), and condomless sex acts within 2 h of using drugs or alcohol (IRR = 0.70, 95 % CI 0.53-0.90). Gender-specific intervention approaches are called for in substance use disorder treatment.
authors.affiliation: Department of Public Health Sciences, University of Miami Miller School of Medicine, Clinical Research Building, Room 1066, 1120 N.W. 14th St., Miami, FL, 33136, USA. panyue@med.miami.edu.
authors.forename: Yue
authors.identifier: http://orcid.org/0000-0001-9586-0975
authors.initials: Y
authors.lastname: Pan
authors.affiliation: Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
authors.forename: Lisa R
authors.initials: LR
authors.lastname: Metsch
authors.affiliation: Department of Biostatistics, Robert Stempel College of Public Health & Social Work at Florida International University, Miami, FL, USA.
authors.forename: Weize
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Biostatistics and Epidemiology, College of Public Health, East Tennessee State University, Johnson City, TN, USA.
authors.forename: Ke-Sheng
authors.initials: KS
authors.lastname: Wang
authors.affiliation: Department of Public Health Sciences, University of Miami Miller School of Medicine, Clinical Research Building, Room 1066, 1120 N.W. 14th St., Miami, FL, 33136, USA.
authors.forename: Rui
authors.initials: R
authors.lastname: Duan
authors.affiliation: Aspire Health Partners, Orlando, FL, USA.
authors.forename: Tiffany L
authors.initials: TL
authors.lastname: Kyle
authors.affiliation: Department of Sociomedical Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
authors.forename: Lauren K
authors.initials: LK
authors.lastname: Gooden
authors.affiliation: Department of Public Health Sciences, University of Miami Miller School of Medicine, Clinical Research Building, Room 1066, 1120 N.W. 14th St., Miami, FL, 33136, USA.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Feaster
mesh_terms: D055030:Drug Users / Q000706:statistics & numerical data*; D005260:Female; D015658:HIV Infections / Q000453:epidemiology / Q000517:prevention & control; D006801:Humans; D008297:Male; D012309:Risk-Taking; D012725:Sexual Behavior / Q000706:statistics & numerical data*; D047568:Unsafe Sex / Q000706:statistics & numerical data*
keywords: Condomless sex; Gender difference; Sexual risk behavior; Substance use disorders treatment; Zero-inflated negative binomial models