title: [Exercise-related risk at anaerobic threshold in patients with chronic obstructive pulmonary disease].
abstract: OBJECTIVE
  To investigate the exercise-related risk at anaerobic threshold(AT) in patients with chronic obstructive pulmonary disease(COPD).
  
  
  METHODS
  Sixty two patients [men 56, women 6, aged (66±8) yr] with stable COPD in Beijing Friendship Hospital during 2013-2014, participated in this study. Incremental symptom-limited cardiopulmonary exercise test was performed on cycle ergometer. The AT was determined using the V-Slope technique and ventilatory equivalents for carbon dioxide and oxygen. Symptoms, 10-lead electrocardiogram, oxygen saturation by pulse oximetry(SpO(2)) were monitored during exercise.
  
  
  RESULTS
  The AT, detectable in 53 patients, occurred at (68±10)% of peak oxygen uptake(peak VO(2)). The SpO(2) was in the safe range (94±2) % and the respiratory reserve was relatively high at AT (i.e. 48%).
  
  
  CONCLUSIONS
  High-intensity exercise training can be performed in patients with moderate-to- severe COPD without resting oxygen desaturation.
authors.affiliation: Beijing Friendship Hospital, Capital University of Medical Science, Beijing 100050, China.
authors.forename: Q F
authors.initials: QF
authors.lastname: Xu
authors.forename: W
authors.initials: W
authors.lastname: Yuan
authors.forename: X J
authors.initials: XJ
authors.lastname: Zhao
authors.forename: B
authors.initials: B
authors.lastname: Li
authors.forename: H Y
authors.initials: HY
authors.lastname: Wang
mesh_terms: D000368:Aged; D015308:Anaerobic Threshold; D002245:Carbon Dioxide / Q000032:analysis; D004562:Electrocardiography; D005080:Exercise Test; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010092:Oximetry; D010100:Oxygen / Q000032:analysis; D029424:Pulmonary Disease, Chronic Obstructive / Q000503:physiopathology*
chemical_list: D002245:Carbon Dioxide; D010100:Oxygen