title: Self-weighing and simple dietary advice for overweight and obese pregnant women to reduce obstetric complications without impact on quality of life: a randomised controlled trial.
abstract: OBJECTIVE
  To determine the effect of serial weighing and dietary advice compared with standard antenatal care on obstetric outcomes.
  
  
  METHODS
  Randomised controlled clinical trial.
  
  
  METHODS
  Australian tertiary obstetric hospital.
  
  
  METHODS
  Three hundred and eighty-two overweight or obese non-diabetic pregnant women at less than 20 weeks gestation with a singleton pregnancy.
  
  
  METHODS
  Women were randomised to targeted, serial self-weighing and simple dietary advice, (intervention), or standard antenatal care (control).
  
  
  METHODS
  The primary outcome was a reduction in a composite of obstetric complications: gestational hypertension, pre-eclampsia, diabetes, assisted or caesarean birth, shoulder dystocia, severe perineal trauma, postpartum haemorrhage and maternal high dependency care. Secondary outcomes were gestational weight gain at 36 weeks' gestation, quality of life (QOL) and maternal serum levels of 28-week leptin, adiponectin and C-reactive protein (CRP).
  
  
  RESULTS
  There was no difference in the rate of the primary composite outcome of obstetric complications: 124/184 (67% control), 124/187 (66% intervention) [relative risk 0.98 (95% confidence interval (CI) 0.85-1.14)]. There was no difference in mean gestational weight gain [-0.9 kg (95% CI -2.0, 0.25)], QOL or leptin, adiponectin or CRP levels between intervention and control groups.
  
  
  CONCLUSIONS
  This low-cost, pragmatic intervention failed to prevent obstetric complications or modify maternal biochemistry or gestational weight gain in overweight or obese pregnant women. Participation in the study did not impair participants' QOL.
  
  
  CONCLUSIONS
  Serial self-weighing and dietary advice failed to reduce obstetric complications in overweight pregnant women.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., Australia.|Mercy Hospital for Women, Heidelberg, Vic., Australia.
authors.forename: E A
authors.initials: EA
authors.lastname: McCarthy
authors.affiliation: Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., Australia.|Mercy Hospital for Women, Heidelberg, Vic., Australia.
authors.forename: S P
authors.initials: SP
authors.lastname: Walker
authors.affiliation: Department of Physiotherapy, Centre for Health, Exercise and Sports Medicine, University of Melbourne, Melbourne, Vic., Australia.
authors.forename: A
authors.initials: A
authors.lastname: Ugoni
authors.affiliation: Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., Australia.
authors.forename: M
authors.initials: M
authors.lastname: Lappas
authors.affiliation: Mercy Hospital for Women, Heidelberg, Vic., Australia.
authors.forename: O
authors.initials: O
authors.lastname: Leong
authors.affiliation: Department of Obstetrics and Gynaecology, University of Melbourne, Melbourne, Vic., Australia.|Mercy Hospital for Women, Heidelberg, Vic., Australia.
authors.forename: A
authors.initials: A
authors.lastname: Shub
mesh_terms: D052242:Adiponectin / Q000097:blood; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000378:metabolism; D004032:Diet; D037001:Directive Counseling; D005260:Female; D005865:Gestational Age; D006801:Humans; D020738:Leptin / Q000097:blood; D009765:Obesity / Q000097:blood* / Q000150:complications; D007744:Obstetric Labor Complications / Q000209:etiology / Q000517:prevention & control*; D011247:Pregnancy; D011295:Prenatal Care; D011788:Quality of Life; D012648:Self Care; D015430:Weight Gain
chemical_list: D052242:Adiponectin; D015415:Biomarkers; D020738:Leptin; D002097:C-Reactive Protein
keywords: Adiponectin; C-reactive protein; body weight changes; inflammation; labour complications; obesity; overweight; pregnancy; prenatal care; quality of life