title: Chronic Lymphocytic Leukemia With Hodgkin and Reed-Sternberg (HRS) Cells: A Potential Diagnostic Pitfall in Lymph Node Biopsies.
abstract: Chronic lymphocytic leukemia (CLL) is known to undergo Richter transformation in a proportion of cases. Transformation into Hodgkin lymphoma has been described in a minority of the cases. However, CLL rarely also shows Hodgkin and Reed-Sternberg cells with a classic morphology and the immunophenotype of Hodgkin lymphoma, even when not in transformation. The presence of these Hodgkin and Reed-Sternberg cells in CLL can cause a diagnostic dilemma.
authors.affiliation: Departments of *Histopathology †Haematology ‡Internal Medicine, Post Graduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
authors.forename: Parimal
authors.initials: P
authors.lastname: Agrawal
authors.forename: Amanjit
authors.initials: A
authors.lastname: Bal
authors.forename: Ashim
authors.initials: A
authors.lastname: Das
authors.forename: ManUpdesh
authors.initials: M
authors.lastname: Sachdeva
authors.forename: Gaurav
authors.initials: G
authors.lastname: Prakash
mesh_terms: D000368:Aged; D001706:Biopsy; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000473:pathology*; D008198:Lymph Nodes / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D016539:Reed-Sternberg Cells / Q000473:pathology*