title: Tumor of the maxilla-odontogenic or glandular? A diagnostic challenge and the role of immunohistochemical markers.
abstract: Today's practice in medicine has reached remarkable change mainly due to the advances in the field. Odontogenic tumors represent a spectrum of lesions ranging from hamartomas to benign and malignant neoplasms. Rarely, odontogenic tumors pose a challenge due to varied histological features. But appropriate and accurate diagnosis is crucial for further treatment and follow-up as these have an influence on the prognosis. In such situations, immunohistochemical. (IHC) markers play a significant role in the differentiating various lesions. Within its palette of histology, there are multiple histopathological presentations, many a times these features come in an intermixed pattern simulating different origin. We here, report such a case presented in a 70-year-old female came with a complaint of swelling in the posterior maxilla. The microscopic findings were indicative of a benign neoplasm. To know the nature of the lesion and arrive at a diagnosis, many IHC markers were used. Based on all these findings, a final diagnosis of unicystic ameloblastoma was arrived.
authors.forename: Jaya
authors.initials: J
authors.lastname: Joshi
authors.affiliation: Faculty of Dentistry, Basic Dental Sciences, Al-Hawaiyah, Taif University, Kingdom of Saudi Arabia.
authors.forename: B S
authors.initials: BS
authors.lastname: Manjunatha
authors.forename: Harish
authors.initials: H
authors.lastname: Kumar
authors.forename: Pratiksha
authors.initials: P
authors.lastname: Kumar
mesh_terms: D000368:Aged; D000564:Ameloblastoma / Q000175:diagnosis* / Q000378:metabolism; D014408:Biomarkers, Tumor / Q000378:metabolism*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008441:Maxillary Neoplasms / Q000175:diagnosis* / Q000378:metabolism; D009807:Odontogenic Cysts / Q000175:diagnosis* / Q000378:metabolism; D009808:Odontogenic Tumors / Q000175:diagnosis* / Q000378:metabolism; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor