title: [A clinical observation of cool-tip radiofrequency ablation assisted enucleation for giant renal angiomyolipoma].
abstract: OBJECTIVE
  To initially explore the clinical effect of cool-tip radiofrequency ablation combined with enucleation for the giant hamartoma of kidney with narrow base and export-oriented way of growth.
  
  
  METHODS
  The clinical date of 15 patients including 6 male and 9 female with special hamartoma of kidney underwent cool-tip radiofrequency ablation assisted enucleation from July 2011 to October 2014 were reviewed.The median age was 49 years (ranging from 35 to 71 years). There were 6 cases with left renal tumor, 8 cases with right renal tumor and 1 case with solitary kidney tumor.All patients were confirmed by B ultrasound or CT scan, the mean diameter of hamartoma of kidney was 9.7 cm(8.5-12.7)cm, all tumors were located distant from the collecting system and presents with a special way of growth.The preoperative hemoglobin was (129±18)g/L, SCr was (92±41)μmol/L, glomerular filtration rate (GFR) was (32±12)ml·min(-1)·1.73 m(-2).
  
  
  RESULTS
  Cool-tip radiofrequency ablation assisted enucleation was technically successful in all patients.The mean operative duration was (115±31)minutes, and the average intraoperative bleeding was (72±21)ml with no blooding transfusion.The postoperative hospital stay was(7±2)days, and the postoperative hemoglobin was(129±18)g/L, SCr (92±41)μmol/L, GFR(30±15)ml·min(-1)·1.73 m(-2). No statistic change of hemoglobin and SCr or glomerular filtration rate after operations(all P>0.05). Postoperative pathology showed that all cases were hamartoma of kidney.During a mean follow-up period of 19.5 months, none of them had local tumor recurrence or chronic renal insufficiency.
  
  
  CONCLUSIONS
  Cool-tip radiofrequency ablation assisted enucleation is both safe and effective in the treatment of huge hamartoma of kidney with a narrow base and export-oriented way of growth. The short-term follow-up shows a satisfactory therapeutic effect.
authors.affiliation: Department of Urology, Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School, Nanjing 210008, China.
authors.forename: Shiwei
authors.initials: S
authors.lastname: Zhang
authors.forename: Lijin
authors.initials: L
authors.lastname: Zhang
authors.forename: Xiaozhi
authors.initials: X
authors.lastname: Zhao
authors.forename: Changwei
authors.initials: C
authors.lastname: Ji
authors.forename: Guangxiang
authors.initials: G
authors.lastname: Liu
authors.forename: Xiaogong
authors.initials: X
authors.lastname: Li
authors.forename: Jiannan
authors.initials: J
authors.lastname: Song
authors.forename: Hongqian
authors.initials: H
authors.lastname: Guo
mesh_terms: D000328:Adult; D000368:Aged; D018207:Angiomyolipoma / Q000601:surgery*; D001803:Blood Transfusion; D017115:Catheter Ablation / Q000379:methods*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007680:Kidney Neoplasms / Q000601:surgery*; D007902:Length of Stay; D008067:Lipoma / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D011184:Postoperative Period; D016896:Treatment Outcome