title: Isolated third ventricle glioblastoma.
abstract: BACKGROUND
  Glioblastoma is the most common and the most malignant type of gliomas. Cerebral hemispheres are usual locations for gliomas. Isolated third ventricular presentation is very rare for glioblastomas. A new case of isolated third ventricular glioblastoma has been presented in this report.
  
  
  METHODS
  A 36-year-old woman was admitted to outpatient clinic with headache, blurred vision and confusion. A head CT scan and MRI had showed third ventricular mass lesion with obstructive hydrocephalus. Previous to her admission to our clinic, a ventriculo-peritoneal shunt had been inserted and her hydrocephalus had been relieved to some extent in acute settings. In our clinic, stereotactic biopsy was performed and a second ventriculoperitoneal shunt was inserted from the opposite site. Histopathological diagnosis was glioblastoma. Radiotherapy and chemotherapy were started immediately after the surgery. Patient's hydrocephalus has resolved and she was well at post-operative 6th month.
  
  
  RESULTS
  In differential diagnosis list of the tumors presenting in the third ventricle, there are plenty of tumors such as colloid cyst, meningioma, germinoma, craniopharyngioma, lymphoma, choroid plexus papilloma, subependymal giant cell astrocytoma, chiasmatic and hypothalamic benign astrocytoma. Ring enhancement of this region pathology is a peculiar sign for glioblastoma, yet not pathognomonic. Tumor histology is crucial to yield the final diagnosis.
  
  
  CONCLUSIONS
  Management of obstructive hydrocephalus, making histopathological diagnosis, starting adjuvant radiotherapy and chemotherapy in isolated third ventricular glioblastomas is a safe and effective approach when we consider malignant nature and intractable progress of glioblastomas.
authors.affiliation: Department of Neurosurgery, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Baran
authors.initials: B
authors.lastname: Yılmaz
authors.affiliation: Department of Orthopedic Surgery-Spine Center, University of California at San Francisco, 500 Parnassus Avenue MU320 West, San Francisco, CA 94143-0728 USA.
authors.forename: Murat Şakir
authors.initials: MŞ
authors.lastname: Ekşi
authors.affiliation: Department of Radiology, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Mustafa Kemal
authors.initials: MK
authors.lastname: Demir
authors.affiliation: Department of Neurosurgery, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Akın
authors.initials: A
authors.lastname: Akakın
authors.affiliation: Department of Neurosurgery, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Zafer Orkun
authors.initials: ZO
authors.lastname: Toktaş
authors.affiliation: Department of Pathology, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Yapıcıer
authors.affiliation: Department of Neurosurgery, Medical Faculty, Bahçeşehir University, Istanbul, Turkey.
authors.forename: Türker
authors.initials: T
authors.lastname: Kılıç
keywords: Biopsy; Glioblastoma; Hydrocephalus; Third ventricle; Ventriculo-peritoneal shunt