title: [New therapeutic strategies in allergic rhinitis].
abstract: Allergic rhinitis (AR) is a nasal inflammatory, IgE-mediated disease that occurs when some individuals inhales something he or she is allergic to, such as pollen or animal dander. It is also a refractory disease with high prevalence in the field of rhinology. The treatment of AR is really a difficult and challenging task because of the high prevalence, economic burden and the interference to the quality of life. At present, nasal corticosteroid and antihistamines were the mainly therapies, however, there is up to 40% patients not satisfactory to these therapies. So exploring new therapy or target is necessary. This article will review the results of previous studies focused on the new therapies of AR.
authors.affiliation: Otorhinolaryngology Department, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
authors.forename: J C
authors.initials: JC
authors.lastname: Sha
authors.affiliation: Otorhinolaryngology Department, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
authors.forename: C D
authors.initials: CD
authors.lastname: Meng
authors.affiliation: Otorhinolaryngology Department, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Xiu
authors.affiliation: Otorhinolaryngology Department, China-Japan Union Hospital of Jilin University, Changchun 130033, China.
authors.forename: D D
authors.initials: DD
authors.lastname: Zhu
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000485:Allergens; D006633:Histamine Antagonists / Q000627:therapeutic use; D015995:Prevalence; D011788:Quality of Life; D065631:Rhinitis, Allergic / Q000628:therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000485:Allergens; D006633:Histamine Antagonists