title: Childhood Body Weight in Relation to Cause-Specific Mortality: 67 Year Follow-up of Participants in the 1947 Scottish Mental Survey.
abstract: The association between childhood body weight and adult health has been little-examined, and findings are inconsistent.In a representative sample of the Scottish nation (the Scottish Mental Survey of 1947), we examined the association between body mass index measured at 11 years of age and future cause-specific mortality by age 77 years. In this cohort study, a maximum of 67 years of follow-up of 3839 study members gave rise to 1568 deaths (758 from cardiovascular disease, 610 from any malignancy). After adjustment for covariates, there was some evidence of a relation between elevated childhood body mass index and rates of mortality ascribed to all-causes (hazard ratio per 1 SD increase in body mass index; 95% confidence interval: 1.09; 1.03, 1.14), cardiovascular disease (1.09; 1.01, 1.17), all cancers combined (1.12; 1.03, 1.21), smoking-related cancers (1.13; 1.03, 1.25), and breast cancer in women (1.27; 1.04, 1.56).In conclusion, we provide further observational evidence for the need for weight control measures in youth.
authors.affiliation: From the Department of Epidemiology and Public Health, University College London (GDB), London; Centre for Cognitive Ageing and Cognitive Epidemiology (GDB, CMC, CEB, IČ, IJD); and Department of Psychology, University of Edinburgh (CMC, CEB, IČ, IJD), Edinburgh, UK.
authors.forename: George David
authors.initials: GD
authors.lastname: Batty
authors.forename: Catherine M
authors.initials: CM
authors.lastname: Calvin
authors.forename: Caroline E
authors.initials: CE
authors.lastname: Brett
authors.forename: Iva
authors.initials: I
authors.lastname: Čukić
authors.forename: Ian J
authors.initials: IJ
authors.lastname: Deary
mesh_terms: D000368:Aged; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D008297:Male; D015999:Multivariate Analysis; D063766:Pediatric Obesity / Q000401:mortality; D011446:Prospective Studies; D012606:Scotland / Q000453:epidemiology