title: Severe Hypokalaemia, Hypertension, and Intestinal Perforation in Ectopic Adrenocorticotropic Hormone Syndrome.
abstract: Ectopic adrenocorticotropic hormone (ACTH) syndrome is a rare cause of the Cushing's syndrome. The occurrence of the ectopic ACTH syndrome presenting with severe hypokalaemia, metabolic alkalosis, and hypertension has been highlighted in case reports. However, presentation with lower gastrointestinal perforation is not known. We report the case of a 70-year-old male patient with severe hypokalaemia, metabolic alkalosis, hypertension, and colonic perforation as manifestations of an ACTH-secreting small cell lung carcinoma. Ectopic ACTH syndrome should be kept in mind as a cause of hypokalaemia, hypertension, and intestinal perforation in patients with lung carcinoma.
authors.affiliation: Assistant Professor, Department of Internal Medicine, Sakarya University Faculty of Medicine , Sakarya, Turkey .
authors.forename: Tezcan
authors.initials: T
authors.lastname: Kaya
authors.affiliation: Medical Doctor, Internal Medicine Specialist, Department of Internal Medicine, Sakarya University Training and Research Hospital , Sakarya, Turkey .
authors.forename: Cengiz
authors.initials: C
authors.lastname: Karacaer
authors.affiliation: Medical Doctor, Research Assistant, Department of Internal Medicine, Sakarya University Faculty of Medicine , Sakarya, Turkey .
authors.forename: Seyyid Bilal
authors.initials: SB
authors.lastname: Açikgöz
authors.affiliation: Assistant Professor, Department of Chest Diseases, Sakarya University Faculty of Medicine , Sakarya, Turkey .
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Aydemir
authors.affiliation: Professor, Department of Internal Medicine, Sakarya University Faculty of Medicine , Sakarya, Turkey .
authors.forename: Ali
authors.initials: A
authors.lastname: Tamer
keywords: Cushing’s syndrome; Hypercortisolism; Lung carcinoma