title: Nevus Lipomatosis Cutaneous Superficialis - A clinicopathologic study of the solitary type.
abstract: BACKGROUND
  Nevus Lipomatosis Cutaneous Superficialis (NLCS) is a rare, benign hamartomatous lesion characterized by the ectopic presence of mature adipocytes in the reticular dermis not associated with the underlying subcutaneous tissue. Two clinical forms-classical and solitary occur. The solitary form is relatively uncommon, due to which these lesions are commonly clinically misdiagnosed. The aim was to study the clinical and histopathological features of the solitary type of NLCS.
  
  
  METHODS
  Seven cases of histopathologically documented solitary type of NLCS which presented at our institute between August 2013 and June 2014 were retrospectively analysed for clinical data and histopathological findings. Haematoxylin and Eosin (H&E) and Elastic Van Gieson (EVG) stained slides were studied in all cases.
  
  
  RESULTS
  Mean age of the patients was 42.5 years. These lesions were more common in adult females (5/7). Thigh was the commonest location (4/7). The mean duration of these lesions was 2.0 years. Clinical diagnosis was papilloma (4/7) and acrochordon (3/7). Histopathology revealed the presence of varying amounts of mature ectopic adipocytes in the dermis located around dilated, ectactic blood vessels. Disorganised dermal collagen bundles and atrophic pilosebaceous units were seen.
  
  
  CONCLUSIONS
  This study is a first from the Indian subcontinent and highlights the need for awareness of this rare clinical condition both by the dermatologists and the surgeons. Histopathology is essential for diagnosis as clinically they may mimic papillomas or skin tags. An early diagnosis may permit a more conservative resection of the tumour.
authors.affiliation: Associate Professor, Army College of Medical Sciences, New Delhi, India.
authors.forename: Sharmila
authors.initials: S
authors.lastname: Dudani
authors.affiliation: Professor (Pathology), Army College of Medical Sciences, New Delhi, India; Senior Advisor (Pathology) & Oncopath, Base Hospital, Delhi Cantt, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Malik
authors.affiliation: Professor & Head, Army College of Medical Sciences, New Delhi, India; Consultant (Pathology), Base Hospital, Delhi Cantt, India.
authors.forename: N S
authors.initials: NS
authors.lastname: Mani
keywords: Hamartoma; Histopathology; Nevus Cutaneous Lipomatosis; Superficialis