title: Increased mean platelet volume in patients with idiopathic subjective tinnitus.
abstract: Tinnitus is the perception of sound with no external stimulus and idiopathic subjective tinnitus is the most common type in adults. Mean platelet volume (MPV) alterations were shown in some inflammatory diseases and were evaluated as a clinically useful marker. Our aim was to investigate MPV alterations in idiopathic subjective tinnitus patients. A total of 101 patients and 54 age- and sex-matched healthy control subjects were enrolled in the study. Patients included in the study had complaints of tinnitus for at least 3 months. All patients underwent detailed otolaryngologic examination, blood sampling, pure tone audiometry, magnetic resonance imaging of ear, and vertebrobasilar artery Doppler ultrasonography to make the differential diagnosis of tinnitus. Blood sampling consisted of renal-liver-thyroid function tests, lipid profile, and complete blood count. All tests and examinations except the imaging modalities were also performed for the control group. There were no differences in age and sex distribution of groups. Mean platelet volume values were significantly increased in tinnitus patients when compared with controls (p = 0.001). We think that MPV can be qualified as a useful marker in tinnitus patients.
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Sarıkaya
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey. cem_dr23@hotmail.com.
authors.forename: Cem
authors.initials: C
authors.lastname: Bayraktar
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karataş
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Doğan
authors.affiliation: Department of Internal Medicine, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Olt
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Kaskalan
authors.affiliation: Department of Internal Medicine, Adıyaman University Research and Education Hospital, 02000, Adıyaman, Turkey.
authors.forename: İbrahim Halil
authors.initials: İH
authors.lastname: Türkbeyler
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count; D016022:Case-Control Studies; D016009:Chi-Square Distribution; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D010976:Platelet Count; D011446:Prospective Studies; D014012:Tinnitus / Q000097:blood* / Q000175:diagnosis
chemical_list: D015415:Biomarkers
keywords: Inflammation; Mean platelet volume; Serum marker; Subjective tinnitus