title: Biomechanical Comparison of Pedicle Screw Augmented with Different Volumes of Polymethylmethacrylate in Osteoporotic and Severely Osteoporotic Synthetic Bone Blocks in Primary Implantation: An Experimental Study.
abstract: This study was designed to compare screw stabilities augmented with different volumes of PMMA and analyze relationship between screw stability and volume of PMMA and optimum volume of PMMA in different bone condition. Osteoporotic and severely osteoporotic synthetic bone blocks were divided into groups A0-A5 and B0-B5, respectively. Different volumes of PMMA were injected in groups A0 to A5 and B0 to B5. Axial pullout tests were performed and F max was measured. F max in groups A1-A5 were all significantly higher than group A0. Except between groups A1 and A2, A3 and A4, and A4 and A5, there were significant differences on F max between any other two groups. F max in groups B1-B5 were all significantly higher than group B0. Except between groups B1 and B2, B2 and B3, and B4 and B5, there were significant differences on F max between any other two groups. There was significantly positive correlation between F max and volume of PMMA in osteoporotic and severely osteoporotic blocks. PMMA can significantly enhance pedicle screw stability in osteoporosis and severe osteoporosis. There were positive correlations between screw stability and volume of PMMA. In this study, injection of 3 mL and 4 mL PMMA was preferred in osteoporotic and severely osteoporotic blocks, respectively.
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Da
authors.initials: D
authors.lastname: Liu
authors.affiliation: Department of Orthopaedics, People's Hospital of Tongchuan, No. 12, Jiankang Road, Tongchuan, Shaanxi 727000, China.
authors.forename: Xiao-jun
authors.initials: XJ
authors.lastname: Zhang
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Dong-fa
authors.initials: DF
authors.lastname: Liao
authors.affiliation: Department of Orthopaedics, 184 Hospital of Nanjing Military Region, No. 4, Hudong Street, Yingtan, Jiangxi 335000, China.
authors.forename: Jiang-jun
authors.initials: JJ
authors.lastname: Zhou
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Zhi-qiang
authors.initials: ZQ
authors.lastname: Li
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhang
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Cai-ru
authors.initials: CR
authors.lastname: Wang
authors.affiliation: Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, No. 15, Changle West Road, Xi'an, Shaanxi 710032, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Lei
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Kang
authors.affiliation: Department of Orthopaedics, Chengdu Military General Hospital, No. 270, Rongdu Avenue, Jinniu District, Chengdu, Sichuan 610083, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zheng
mesh_terms: D001696:Biomechanical Phenomena; D001843:Bone Cements / Q000627:therapeutic use; D015519:Bone Density; D006801:Humans; D008159:Lumbar Vertebrae / Q000473:pathology*; D010024:Osteoporosis / Q000473:pathology / Q000628:therapy*; D065289:Pedicle Screws; D019904:Polymethyl Methacrylate / Q000737:chemistry / Q000627:therapeutic use
chemical_list: D001843:Bone Cements; D019904:Polymethyl Methacrylate