title: A systematic review on the long-term success of calcium phosphate plasma-spray-coated dental implants.
abstract: The objectives of the current review were (1) to systematically appraise, and (2) to evaluate long-term success data of calcium phosphate (CaP) plasma-spray-coated dental implants in clinical trials with at least 5 years of follow-up. To describe the long-term efficacy of functional implants, the outcome variables were (a) percentage annual complication rate (ACR) and (b) cumulative success rate (CSR), as presented in the selected articles. The electronic search yielded 645 titles. On the basis of the inclusion criteria, 8 studies were finally included. The percentage of implants in function after the first year was estimated to be 98.4 % in the maxilla and 99.2 % in the mandible. The estimates of the weighted mean ACR-percentage increased over the years up to 2.6 (SE 0.7) during the fifth year of function for the maxilla and to 9.4 (SE 8.4) for the mandible in the tenth year of function. After 10 years, the mean percentage of successful implants was estimated to be 71.1 % in the maxilla and 72.2 % in the mandible. The estimates seem to confirm the proposed, long-term progressive bone loss pattern of CaP-ceramic-coated dental implants. Within the limits of this meta-analytic approach to the literature, we conclude that: (1) published long-term success data for calcium phosphate plasma-spray-coated dental implants are limited, (2) comparison of the data is difficult due to differences in success criteria among the studies, and (3) long-term CSRs demonstrate very weak evidence for progressive complications around calcium phosphate plasma-spray-coated dental implants.
authors.affiliation: Department of Biomaterials, College of Dental Sciences, Radboudumc, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. Bart.vanoirschot@radboudumc.nl.
authors.forename: B A J A
authors.initials: BA
authors.lastname: van Oirschot
authors.affiliation: Department of Preventive and Curative Dentistry, Radboudumc, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
authors.forename: E M
authors.initials: EM
authors.lastname: Bronkhorst
authors.affiliation: Department of Biomaterials, College of Dental Sciences, Radboudumc, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
authors.forename: J J J P
authors.initials: JJ
authors.lastname: van den Beucken
authors.affiliation: Department of Implantology and Periodontology, Radboudumc, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
authors.forename: G J
authors.initials: GJ
authors.lastname: Meijer
authors.affiliation: Department of Biomaterials, College of Dental Sciences, Radboudumc, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.
authors.forename: J A
authors.initials: JA
authors.lastname: Jansen
authors.affiliation: Department of Prosthodontics and Biomaterials, Danube Private University, Krems a.d. Donau, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Junker
mesh_terms: D002130:Calcium Phosphates / Q000737:chemistry*; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; D019232:Dental Restoration Failure; D006801:Humans; D013499:Surface Properties; D016896:Treatment Outcome
chemical_list: D002130:Calcium Phosphates; D020099:Coated Materials, Biocompatible; D015921:Dental Implants
keywords: Calcium phosphate; Coating; Long-term success; Plasma-spray; Systematic review