title: The Alga Ochromonas danica Produces Bromosulfolipids.
abstract: Many halogenases interchangeably incorporate chlorine and bromine into organic molecules. On the basis of an unsubstantiated report that the alga Ochromonas danica, a prodigious producer of chlorosulfolipids, was able to produce bromosulfolipids, we have investigated the promiscuity of its halogenases toward bromine incorporation. We have found that bromosulfolipids are produced with the exact positional and stereochemical selectivity as in the chlorosulfolipid danicalipin A when this alga is grown under modified conditions containing excess bromide ion.
authors.affiliation: Department of Chemistry, University of California , 1102 Natural Sciences II, Irvine, California 92617, United States.
authors.forename: Alexander R
authors.initials: AR
authors.lastname: White
authors.affiliation: School of Pharmacy and Pharmaceutical Science, University of California , 9500 Gilman Drive, #0684, San Diego, California 92093, United States.
authors.forename: Brendan M
authors.initials: BM
authors.lastname: Duggan
authors.affiliation: Department of Chemistry, University of California , 1102 Natural Sciences II, Irvine, California 92617, United States.|Department of Molecular Biology and Biochemistry, University of California , 3205 McGaugh Hall, Irvine, California 92617, United States.
authors.forename: Shiou-Chuan
authors.initials: SC
authors.lastname: Tsai
authors.affiliation: Department of Chemistry, University of California , 1102 Natural Sciences II, Irvine, California 92617, United States.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Vanderwal
mesh_terms: D006842:Hydrocarbons, Brominated / Q000737:chemistry / Q000302:isolation & purification*; D008055:Lipids / Q000737:chemistry / Q000302:isolation & purification*; D015394:Molecular Structure; D044663:Ochromonas / Q000737:chemistry*
chemical_list: D006842:Hydrocarbons, Brominated; D008055:Lipids; C000609066:bromodanicalipin A; C557671:danicalipin A; C015518:sulfolipids