title: S segment variability during the two first years of the spread of Schmallenberg virus.
abstract: A large sheep flock screened over a two-year period showed active spreading of Schmallenberg virus (SBV) during the summers of 2011 and 2012. Transplacental infections were observed during the two associated lambing periods (the winters of 2012 and 2013). Analysis of small (S) segment sequences of 38 SBV-positive samples, collected during periods of viral spreading and lambing revealed intra-herd sequences diversity and sub-consensus variability occurring after transplacental infections. In comparison with the nucleoprotein (N), which appeared to be conserved, the non-structural protein (NSs) showed the highest level of variability at the time of viral emergence and over the two-year analysis period.
authors.affiliation: Veterinary Department, Faculty of Sciences, Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), 61 rue de Bruxelles, 5000, Namur, Belgium.
authors.forename: Damien
authors.initials: D
authors.lastname: Coupeau
authors.affiliation: Veterinary Department, Faculty of Sciences, Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), 61 rue de Bruxelles, 5000, Namur, Belgium.
authors.forename: François
authors.initials: F
authors.lastname: Claine
authors.affiliation: Veterinary Department, Faculty of Sciences, Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), 61 rue de Bruxelles, 5000, Namur, Belgium.
authors.forename: Laetitia
authors.initials: L
authors.lastname: Wiggers
authors.affiliation: Veterinary Department, Faculty of Sciences, Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), 61 rue de Bruxelles, 5000, Namur, Belgium.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Kirschvink
authors.affiliation: Veterinary Department, Faculty of Sciences, Namur Research Institute for Life Sciences (NARILIS), University of Namur (UNamur), 61 rue de Bruxelles, 5000, Namur, Belgium. benoit.muylkens@unamur.be.
authors.forename: Benoît
authors.initials: B
authors.lastname: Muylkens
mesh_terms: D000818:Animals; D002044:Bunyaviridae Infections / Q000662:veterinary* / Q000821:virology; D014644:Genetic Variation / Q000235:genetics; D016366:Open Reading Frames / Q000235:genetics; D016851:Orthobunyavirus / Q000235:genetics*; D012367:RNA, Viral / Q000235:genetics; D012756:Sheep; D012757:Sheep Diseases / Q000821:virology*
chemical_list: D012367:RNA, Viral
keywords: Bunyaviridae; NSs; Nucleoprotein; S segment; Sub-consensus variability