title: Effect of laryngopharyngeal reflux on the improvement of chronic rhinosinusitis without polyposis after primary endoscopic sinus surgery.
abstract: OBJECTIVE
  This study aims to investigate the influence of laryngopharyngeal reflux on the improvement of chronic rhinosinusitis (CRS) in patients who underwent endoscopic sinus surgery (ESS).
  
  
  METHODS
  A total of 48 patients (28 males, 20 females; mean age 41.6±15.1 years; range 18 to 75 years) with CRS without polyposis were assessed for the presence of gastric reflux with Reflux Symptom Index (RSI) and Reflux Finding Scores (RFS) before undergoing primary ESS. Patients with a RSI >12 and RFS >7 were included in the reflux(+) and those with either score under these cutoffs in the reflux(-) group. Improvement scores were accepted as the difference between preoperative scores and postoperative sixth-month Lund-Mackay Radiology Scores, Lund-Kennedy Endoscopy Scores (LKES), and Sinusitis Symptom Scores (SSS).
  
  
  RESULTS
  There was no significant difference between improvements of the reflux(+) and reflux(-) groups in terms of radiology, endoscopy, and symptom scores (p>0.05). However, preoperative and postoperative six-month radiology scores were significantly higher in reflux(+) patients (p<0.01). Also, postoperative six-month LKES were significantly higher in reflux(+) patients. No statistically significant differences were detected between preoperative and postoperative six-month SSS in reflux(+) or reflux(-) patients.
  
  
  CONCLUSIONS
  Laryngopharyngeal reflux was associated with worse radiology and endoscopy scores in CRS without polyposis; however, it had no role on the improvement scores after primary ESS.
authors.affiliation: Department of Otolaryngology, Haydarpaşa Numune Training and Research Hospital, 34668 Üsküdar, İstanbul, Turkey. aysegulverim@hotmail.com.
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Verim
authors.forename: Lütfü
authors.initials: L
authors.lastname: Şeneldir
authors.forename: Barış
authors.initials: B
authors.lastname: Naiboğlu
authors.forename: Çiğdem
authors.initials: Ç
authors.lastname: Tepe Karaca
authors.forename: Dinçer
authors.initials: D
authors.lastname: Kadıoğlu
authors.forename: Sema
authors.initials: S
authors.lastname: Zer Toros
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002908:Chronic Disease; D004724:Endoscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D057045:Laryngopharyngeal Reflux / Q000150:complications*; D007828:Laryngoscopy / Q000379:methods; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012220:Rhinitis / Q000601:surgery*; D012852:Sinusitis / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult