title: Zika virus and the risk of imported infection in returned travelers: Implications for clinical care.
abstract: Since late 2015, an unprecedented outbreak of Zika virus is spreading quickly across Southern America. The large size of the current outbreak in The Americas will also result in an increase in Zika virus infections among travelers returning from endemic areas. We report five cases of imported Zika virus infection to The Netherlands. Although the clinical course is usually mild, establishing the diagnosis is important, mainly because of the association with congenital microcephaly and the possibility of sexual transmission.
authors.affiliation: Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands. Electronic address: a.goorhuis@amc.uva.nl.
authors.forename: Abraham
authors.initials: A
authors.lastname: Goorhuis
authors.affiliation: Laboratory of Clinical Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Karin J
authors.initials: KJ
authors.lastname: von Eije
authors.affiliation: Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Renée A
authors.initials: RA
authors.lastname: Douma
authors.affiliation: Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Noor
authors.initials: N
authors.lastname: Rijnberg
authors.affiliation: Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Michele
authors.initials: M
authors.lastname: van Vugt
authors.affiliation: Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Cornelis
authors.initials: C
authors.lastname: Stijnis
authors.affiliation: Center of Tropical Medicine and Travel Medicine, Department of Infectious Diseases, Division of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Martin P
authors.initials: MP
authors.lastname: Grobusch
mesh_terms: D000328:Adult; D000569:Americas; D004196:Disease Outbreaks / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008831:Microcephaly / Q000821:virology; D008875:Middle Aged; D009426:Netherlands; D012307:Risk Factors; D015229:Sexually Transmitted Diseases, Viral / Q000175:diagnosis / Q000635:transmission*; D013020:South America / Q000453:epidemiology; D014195:Travel; D014481:United States; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification; D000071243:Zika Virus Infection / Q000175:diagnosis / Q000453:epidemiology* / Q000635:transmission* / Q000821:virology
keywords: Case series; Microcephaly; Sexual transmission; Travel; Zika virus