title: Influence of Self-Assembled Alkanethiol Monolayers on Stochastic Amperometric On-Chip Detection of Silver Nanoparticles.
abstract: We investigate the influence of self-assembled alkanethiol monolayers at the surface of platinum microelectrode arrays on the stochastic amperometric detection of citrate-stabilized silver nanoparticles in aqueous solutions. The measurements were performed using a microelectrode array featuring 64 individually addressable electrodes that are recorded in parallel with a sampling rate of 10 kHz for each channel. We show that both the functional end group and the total length of the alkanethiol influence the charge transfer. Three different terminal groups, an amino, a hydroxyl, and a carboxyl, were investigated using two different molecule lengths of 6 and 11 carbon atoms. Finally, we show that a monolayer of alkanethiols with a length of 11 carbon atoms and a carboxyl terminal group can efficiently block the charge transfer of free nanoparticles in an aqueous solution.
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
authors.forename: Kay J
authors.initials: KJ
authors.lastname: Krause
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
authors.forename: Nouran
authors.initials: N
authors.lastname: Adly
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
authors.forename: Alexey
authors.initials: A
authors.lastname: Yakushenko
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Schnitker
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
authors.forename: Dirk
authors.initials: D
authors.lastname: Mayer
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Offenhäusser
authors.affiliation: Institute of Bioelectronics (PGI-8/ICS-8) and JARA-Fundamentals of Future Information Technology, Forschungszentrum Jülich , 52425 Jülich, Germany.|Neuroelectronics, IMETUM, Department of Electrical and Computer Engineering, Technical University of Munich (TUM) , Boltzmannstrasse 11, 85748 Garching, Germany.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Wolfrum
mesh_terms: D055664:Electrochemical Techniques; D004566:Electrodes; D056656:Lab-On-A-Chip Devices; D053768:Metal Nanoparticles / Q000032:analysis* / Q000737:chemistry; D008956:Models, Chemical; D010084:Oxidation-Reduction; D012834:Silver / Q000032:analysis* / Q000737:chemistry; D013269:Stochastic Processes; D013438:Sulfhydryl Compounds / Q000737:chemistry*
chemical_list: D013438:Sulfhydryl Compounds; D012834:Silver