title: Kin Discrimination in Protists: From Many Cells to Single Cells and Backwards.
abstract: During four decades (1960-1990s), the conceptualization and experimental design of studies in kin recognition relied on work with multicellular eukaryotes, particularly Unikonta (including invertebrates and vertebrates) and some Bikonta (including plants). This pioneering research had an animal behavior approach. During the 2000s, work on taxa-, clone- and kin-discrimination and recognition in protists produced genetic and molecular evidence that unicellular organisms (e.g. Saccharomyces, Dictyostelium, Polysphondylium, Tetrahymena, Entamoeba and Plasmodium) could distinguish between same (self or clone) and different (diverse clones), as well as among conspecifics of close or distant genetic relatedness. Here, we discuss some of the research on the genetics of kin discrimination/recognition and highlight the scientific progress made by switching emphasis from investigating multicellular to unicellular systems (and backwards). We document how studies with protists are helping us to understand the microscopic, cellular origins and evolution of the mechanisms of kin discrimination/recognition and their significance for the advent of multicellularity. We emphasize that because protists are among the most ancient organisms on Earth, belong to multiple taxonomic groups and occupy all environments, they can be central to reexamining traditional hypotheses in the field of kin recognition, reformulating concepts, and generating new knowledge.
authors.affiliation: New England Center for the Public Understanding of Science, Roger Williams University, One Old Ferry Road, Bristol, Rhode Island, 02809.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Paz-Y-Miño-C
authors.affiliation: New England Center for the Public Understanding of Science, Roger Williams University, One Old Ferry Road, Bristol, Rhode Island, 02809.|Department of Biology, Roger Williams University, One Old Ferry Road, Bristol, Rhode Island, 02809.
authors.forename: Avelina
authors.initials: A
authors.lastname: Espinosa
mesh_terms: D000483:Alleles; D000818:Animals; D005075:Biological Evolution; D056890:Eukaryota / Q000145:classification* / Q000235:genetics* / Q000502:physiology; D056084:Genetic Fitness; D010641:Phenotype
keywords: Antirecognition strategies; cheaters and resisters; communication problem; green-beard effect; honest signals; inclusive fitness; kin selection; phenotype matching; recognition alleles