title: [Comparison of welder's pneumoconiosis with silicosis and follow-up study of welder's pneumoconiosis].
abstract: OBJECTIVE
  To study the character of welder's pneumoconiosis on CT, pathology, and lung function.
  
  
  METHODS
  To contrast 185 welder's pneumoconiosis and 115 silicosis on CT, pathology, and clinical characters which were diagnosed between Jan 2008 and Dec 2013. Chest X-ray and lung function of 39 welder's pneumoconiosis patients were followed up after diagnosed 4~6 years later.
  
  
  RESULTS
  Average age and working years of welder's pneumoconiosis were 36.7 and 11.5, less than silicosis patients 58.8 and 22.1, respectively (P<0.05). Of all 185 welder's pneumoconiosis 98.4% were of stage I and no stage III, while in silicosis group stage I, stage II and stage III were 56.5%, 22.6% and 20.9%, respectively. The ratio differences between the two groups were statistically significant,P<0.05. 82.7% of welder's pneumoconiosis patients were observed pathologically moderate or above dust deposition in lung tissue while interstitial fibrosis level was just mild (97.6% patients) or no fibrosis (2.4% patients). By contrast, 60.0% silicosis patients pathologically showed moderate or above dust deposition while 77.8% were of moderate or above fibrosis. CT findings in welder' s pneumoconiosis were diffuse branching linear structure (38.9%), low density consistent size centrilobular micronodules (19.5%), or both (30.8%). Poorly-defined ground-glass attenuation centrilobular micronodules or widely ground glass shadow were observed in 6.4% welder's pneumoconiosis patents. 30.8% patients failed to reach the original stage when 39 welder's pneumoconiosis followed up chest radiograph.
  
  
  CONCLUSIONS
  Changes in welder's lung caused by welding fume were not only siderosis, but also interstitial fibrosis.
authors.affiliation: Shanghai Pulmonary Hospital , Tongji University School of Medicine, Shanghai 200433, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Shi
authors.affiliation: Shanghai Pulmonary Hospital , Tongji University School of Medicine, Shanghai 200433, China; E-mail: maoling113@sina.com.
authors.forename: Ling
authors.initials: L
authors.lastname: Mao
authors.affiliation: Shanghai Pulmonary Hospital , Tongji University School of Medicine, Shanghai 200433, China.
authors.forename: Zidan
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Shanghai Pulmonary Hospital , Tongji University School of Medicine, Shanghai 200433, China.
authors.forename: Shaowei
authors.initials: S
authors.lastname: Zhou
authors.affiliation: Shanghai Pulmonary Hospital , Tongji University School of Medicine, Shanghai 200433, China.
authors.forename: Luqin
authors.initials: L
authors.lastname: Bian
authors.affiliation: Shanghai Pulmonary Hospital , Tongji University School of Medicine, Shanghai 200433, China.
authors.forename: Daoyuan
authors.initials: D
authors.lastname: Sun
mesh_terms: D000328:Adult; D004391:Dust; D005355:Fibrosis; D005500:Follow-Up Studies; D005898:Glass; D006801:Humans; D008168:Lung / Q000473:pathology; D008875:Middle Aged; D011009:Pneumoconiosis / Q000503:physiopathology*; D013902:Radiography, Thoracic; D012806:Siderosis / Q000503:physiopathology; D012829:Silicosis / Q000175:diagnosis / Q000503:physiopathology*; D014896:Welding
chemical_list: D004391:Dust