title: Yttrium-90 Radioembolization for Hepatocellular Carcinoma.
abstract: (90)Y radioembolization refers to the selective, transcatheter, and intra-arterial injection of micrometer-sized particles loaded with the radioisotope yttrium-90 for the treatment of primary and metastatic hepatic malignancies. In the treatment of intermediate- and advanced-stage hepatocellular carcinoma, (90)Y radioembolization provides favorable outcomes with minimal side effects, offering an alternative treatment option to other transarterial therapies, such as bland embolization and chemoembolization. This review provides an overview of the use of (90)Y radioembolization in the treatment of hepatocellular carcinoma, including patient selection criteria, dosimetry, and clinical outcomes.
authors.affiliation: Department of Radiology, Division of Vascular & Interventional Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL.
authors.forename: Ryan M
authors.initials: RM
authors.lastname: Hickey
authors.affiliation: Department of Radiology, Division of Vascular & Interventional Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Lewandowski
authors.affiliation: Department of Radiology, Division of Vascular & Interventional Radiology, Northwestern University, Feinberg School of Medicine, Chicago, IL. Electronic address: r-salem@northwestern.edu.
authors.forename: Riad
authors.initials: R
authors.lastname: Salem
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000532:radiotherapy*; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000532:radiotherapy*; D018579:Patient Selection; D011874:Radiometry; D015021:Yttrium Radioisotopes / Q000627:therapeutic use*
chemical_list: D015021:Yttrium Radioisotopes