title: Plain to point network reduced graphene oxide-activated carbon composites decorated with platinum nanoparticles for urine glucose detection.
abstract: In this study, a hydrothermal technique was applied to synthesize glucose-treated reduced graphene oxide-activated carbon (GRGO/AC) composites. Platinum nanoparticles (PtNP) were electrochemically deposited on the modified GRGO/AC surface, and chitosan-glucose oxidase (Chit-GOx) composites and nafion were integrated onto the modified surface of the working electrode to prepare a highly sensitive glucose sensor. The fabricated biosensor exhibited a good amperometric response to glucose in the detection range from 0.002 mM to 10 mM, with a sensitivity of 61.06 μA/mMcm(2), a short response time (4 s) and a low detection limit of 2 μM (signal to noise ratio is 3). The glucose sensor exhibited a negligible response to interference and good stability. In addition, the glucose levels in human urine were tested in order to conduct a practical assessment of the proposed sensor, and the results indicate that the sensor had superior urine glucose recognition. These results thus demonstrate that the noble nano-structured electrode with a high surface area and electrocatalytic activity offers great promise for use in urine glucose sensing applications.
authors.affiliation: Department of Electronic Engineering, Micro/Nano Devices &packaging Lab., Kwangwoon University, 447-1, Wolgye-Dong, Nowon Gu, Seoul, 139-701, Korea.
authors.forename: Mohammad Faruk
authors.initials: MF
authors.lastname: Hossain
authors.affiliation: Department of Electronic Engineering, Micro/Nano Devices &packaging Lab., Kwangwoon University, 447-1, Wolgye-Dong, Nowon Gu, Seoul, 139-701, Korea.
authors.forename: Jae Y
authors.initials: JY
authors.lastname: Park
mesh_terms: D015374:Biosensing Techniques; D005947:Glucose / Q000737:chemistry / Q000302:isolation & purification*; D005949:Glucose Oxidase / Q000737:chemistry; D006029:Glycosuria / Q000652:urine*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry; D010984:Platinum / Q000737:chemistry
chemical_list: D037742:Nanotubes, Carbon; D010984:Platinum; D005949:Glucose Oxidase; D005947:Glucose