title: Translational Bioinformatics: Past, Present, and Future.
abstract: Though a relatively young discipline, translational bioinformatics (TBI) has become a key component of biomedical research in the era of precision medicine. Development of high-throughput technologies and electronic health records has caused a paradigm shift in both healthcare and biomedical research. Novel tools and methods are required to convert increasingly voluminous datasets into information and actionable knowledge. This review provides a definition and contextualization of the term TBI, describes the discipline's brief history and past accomplishments, as well as current foci, and concludes with predictions of future directions in the field.
authors.affiliation: Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: jessie.tenenbaum@duke.edu.
authors.forename: Jessica D
authors.initials: JD
authors.lastname: Tenenbaum
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D035843:Biomedical Research; D019295:Computational Biology; D016208:Databases, Factual; D055106:Genome-Wide Association Study; D023281:Genomics; D006801:Humans; D057285:Precision Medicine
chemical_list: D015415:Biomarkers
keywords: Biomarkers; Genomics; Personalized medicine; Precision medicine; Translational bioinformatics