title: Cerebellar metastases of recurrent phyllodes tumor breast; a rare phenomenon reflecting the unpredictable outcome.
abstract: Carcinomas of lung, breast, colon, kidney, and malignant melanomas are the most common malignancies that metastasize to the central nervous system (CNS). Phyllodes tumor is a rare fibroepithelial tumor of the breast, often having unpredictable recurrences, with increasing histological grade and distant metastasis. Malignant forms exist, which may develop distant metastases usually to the lung, pleura, bone, and liver. CNS metastasis of phyllodes tumor is rare and associated with a poor prognosis, with resistance to chemotherapy and radiation. We present a rare case of cerebellar metastasis in recurrent phyllodes tumor breast with subsequent rapid downhill course.
authors.forename: Jyotsna
authors.initials: J
authors.lastname: Singh
authors.forename: Kaushik
authors.initials: K
authors.lastname: Majumdar
authors.forename: Rahul
authors.initials: R
authors.lastname: Gupta
authors.affiliation: Department of Pathology, Academic Block, Govind Ballabh Pant Hospital, New Delhi, India.
authors.forename: Vineeta Vijay
authors.initials: VV
authors.lastname: Batra
mesh_terms: D000328:Adult; D001943:Breast Neoplasms / Q000473:pathology* / Q000601:surgery; D002528:Cerebellar Neoplasms / Q000556:secondary* / Q000601:surgery; D005260:Female; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology* / Q000601:surgery; D003557:Phyllodes Tumor / Q000473:pathology* / Q000601:surgery; D011379:Prognosis; D035583:Rare Diseases / Q000473:pathology* / Q000601:surgery