title: Cascade DNA logic device programmed ratiometric DNA analysis and logic devices based on a fluorescent dual-signal probe of a G-quadruplex DNAzyme.
abstract: Herein, two fluorescence sensitive substrates of G-quadruplex/hemin DNAzyme with inverse responses (Scopoletin and Amplex Red) were simultaneously used in one homogeneous system to construct a cascade advanced DNA logic device for the first time (a functional logic device (a three input based DNA calliper) cascade with an advanced non-arithmetic logic gate (1 to 2 decoder)). This cascade logic device was applied to label-free ratiometric target DNA detection and length measurement.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China. dongsj@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing, 100039, China.
authors.forename: Daoqing
authors.initials: D
authors.lastname: Fan
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China. dongsj@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing, 100039, China.
authors.forename: Jinbo
authors.initials: J
authors.lastname: Zhu
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China. dongsj@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing, 100039, China.
authors.forename: Qingfeng
authors.initials: Q
authors.lastname: Zhai
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China. dongsj@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing, 100039, China.
authors.forename: Erkang
authors.initials: E
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, P. R. China. dongsj@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing, 100039, China.
authors.forename: Shaojun
authors.initials: S
authors.lastname: Dong
mesh_terms: D004247:DNA / Q000032:analysis / Q000737:chemistry*; D021881:DNA, Catalytic / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*
chemical_list: D021881:DNA, Catalytic; D005456:Fluorescent Dyes; D004247:DNA