title: Dose response characteristics of a novel CCD camera-based electronic portal imaging device comparison with OCTAVIUS detector.
abstract: OBJECTIVE
  Dosimetric properties of a CCD camera-based Electronic Portal Imaging Device (EPID) for clinical dosimetric application have been evaluated. Characteristics obtained by EPID also compared with commercial 2D array of ion chambers.
  
  
  METHODS
  Portal images acquired in dosimetry mode then exported raw fluence or uncorrected images were investigated. Integration time of image acquisition mode has adjusted on 1 s per frame.
  
  
  RESULTS
  As saturation of camera of the EPID, dose response does not have linear behavior. The slight nonlinearity of the camera response can be corrected by a logarithmic expression. A fourth order polynomial regression model with coefficient of determination of 0.998 predicts a response to absolute dose values at less than 50 cGy. A field size dependent response of up to 7% (0.99-1.06) relative OCTAVIUS detector measurement was found. The EPID response can be fitted by a cubic regression for field size changes, yielded coefficient of determination of 0.999.
  
  
  CONCLUSIONS
  These results indicate that the EPID is well suited for accurate dosimetric purposes, the major limitation currently being due to integration time and dead-time in frame acquisition.
authors.affiliation: Department of Radiation Medicine Engineering, Shahid Beheshti University, Tehran, Iran.
authors.forename: Akbar
authors.initials: A
authors.lastname: Anvari
authors.forename: Seyed Mahmoud Reza
authors.initials: SM
authors.lastname: Aghamiri
authors.forename: Seyed Rabie
authors.initials: SR
authors.lastname: Mahdavi
authors.forename: Parham
authors.initials: P
authors.lastname: Alaei
mesh_terms: D055615:Electrical Equipment and Supplies; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation* / Q000379:methods; D009369:Neoplasms / Q000532:radiotherapy*; D011874:Radiometry / Q000295:instrumentation*; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*