title: Improving the safety of vaccine delivery.
abstract: Vaccines save millions of lives per annum as an integral part of community primary care provision worldwide. Adverse events due to the vaccine delivery process outnumber those arising from the pharmacological properties of the vaccines themselves. Whilst one in three patients receiving a vaccine will encounter some form of error, little is known about their underlying causes and how to mitigate them in practice. Patient safety incident reporting systems and adverse drug event surveillance offer a rich opportunity for understanding the underlying causes of those errors. Reducing harm relies on the identification and implementation of changes to improve vaccine safety at multiple levels: from patient interventions through to organizational actions at local, national and international levels. Here we highlight the potential for maximizing learning from patient safety incident reports to improve the quality and safety of vaccine delivery.
authors.affiliation: a Primary Care Patient Safety (PISA) Research Group, School of Medicine, Cardiff University , Cardiff , Wales.
authors.forename: Huw P
authors.initials: HP
authors.lastname: Evans
authors.affiliation: a Primary Care Patient Safety (PISA) Research Group, School of Medicine, Cardiff University , Cardiff , Wales.
authors.forename: Alison
authors.initials: A
authors.lastname: Cooper
authors.affiliation: a Primary Care Patient Safety (PISA) Research Group, School of Medicine, Cardiff University , Cardiff , Wales.
authors.forename: Huw
authors.initials: H
authors.lastname: Williams
authors.affiliation: a Primary Care Patient Safety (PISA) Research Group, School of Medicine, Cardiff University , Cardiff , Wales.|b Department of Family Practice , Faculty of Medicine, University of British Columbia , Vancouver , Canada.|c Institute of Healthcare Policy and Practice, University of the West of Scotland , Paisley , Scotland.
authors.forename: Andrew
authors.initials: A
authors.lastname: Carson-Stevens
mesh_terms: D016907:Adverse Drug Reaction Reporting Systems; D016208:Databases, Factual; D016503:Drug Delivery Systems / Q000009:adverse effects; D006801:Humans; D061214:Patient Safety; D014612:Vaccines / Q000008:administration & dosage* / Q000009:adverse effects
chemical_list: D014612:Vaccines
keywords: adverse event monitoring; data linkage; incident reporting; vaccine errors; vaccine safety