title: Primary and Metastatic Liver Malignancy: Utility Low and High B Value (1600-2000) in 3 Tesla MRI.
abstract: OBJECTIVE
  To determine the utility of the quantitative apparent diffusion coefficient (ADC) values at various b values, in the differentiation of malignant hepatic masses on 3.0 Tesla (T) MRI.
  
  
  METHODS
  We evaluated 81 consecutive patients presenting with 529 malignant masses in the liver. Of those patients 27 had a primary hepatic malignancy while the other 54 patients had metastases in the liver. Quantitative ADC values of malignant hepatic masses was measured at four b values (b 400, b 800, b 1600, b 2000 mm2/s) on MR-DWI. We compared the primary and metastatic tumors within their groups and also with each other in terms of their ADC values.
  
  
  RESULTS
  In 4 various b value measurements, the mean ADC values of the primary and metastatic hepatic masses were 1. x 10(-3), 1.06 x 10(-3), 0.87 x 10(-3), and 0.736 x 10(-3)mm2/ seconds, 1.30 x 10(-3), 1.10 x 10(-3), 0.84 x 10(-3), and 0.715 x 10(-3) mm2/seconds respectively. There was no significant difference between mean ADC values of HCCs and metastases at b 400, 800, 1600 and 2000 gradients (P > 0.05).
  
  
  CONCLUSIONS
  The ADC values obtained at intermediate (400, 800) and high (b 1600, 2000) diffusion gradients are not helpful in differentiation between HCCs and liver metastases.
authors.forename: Cemil
authors.initials: C
authors.lastname: Göya
authors.forename: Cihad
authors.initials: C
authors.lastname: Hamidi
authors.forename: Hakan
authors.initials: H
authors.lastname: Önder
authors.forename: Ali
authors.initials: A
authors.lastname: Inal
authors.forename: Güven
authors.initials: G
authors.lastname: Tekbaş
authors.forename: Uğur
authors.initials: U
authors.lastname: Firat
authors.forename: Mehmet Güli
authors.initials: MG
authors.lastname: Çetinçakmak
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001650:Bile Duct Neoplasms / Q000175:diagnosis*; D006528:Carcinoma, Hepatocellular / Q000175:diagnosis*; D002648:Child; D018281:Cholangiocarcinoma / Q000175:diagnosis*; D015331:Cohort Studies; D015179:Colorectal Neoplasms / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D005706:Gallbladder Neoplasms / Q000473:pathology; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000556:secondary; D008175:Lung Neoplasms / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000473:pathology; D011446:Prospective Studies; D013274:Stomach Neoplasms / Q000473:pathology; D055815:Young Adult