title: Commentary: Making the brain matter in assessing and treating adolescent substance use--a commentary on Conrod and Nikolaou (2016).
abstract: Adolescence represents a period of vulnerability to psychiatric problems due to a range of factors, including advances in social and cognitive abilities, increased levels of autonomy in decision-making and behavioral governance, and greater exposure to opportunities for risk-taking behavior. Adding to these psychological and social challenges, adolescence also is marked by robust maturational changes affecting both the microcircuitry and connectivity between widely distributed brain systems. These changes alter the communication among parallel, distributed brain networks, have implications for one's vulnerability to engage in risk behavior and make the brain particularly susceptible to external perturbations, such as exposure to neurotoxic substances.
authors.affiliation: Clinical Child Psychology Program, University of Kansas, Lawrence, KS, USA.|Schiefelbusch Institute for Life Span Studies, University of Kansas, Lawrence, KS, USA.
authors.forename: Matthew W
authors.initials: MW
authors.lastname: Mosconi
authors.affiliation: Department of Psychology, University of Kansas, Lawrence, KS, USA.
authors.forename: Carl W
authors.initials: CW
authors.lastname: Lejuez
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior / Q000523:psychology*; D001921:Brain; D003657:Decision Making; D006801:Humans; D012309:Risk-Taking; D019966:Substance-Related Disorders / Q000523:psychology
keywords: Substance use