title: Targeted Temperature Modulation in the Neuroscience Patient.
abstract: There are many approaches to and opportunities for implementing temperature modulation in critically ill patients, but barriers also exist. Conceptually, the process of cooling is rather straightforward; however, targeted temperature management is anything but simplistic. The need for a collaborative approach (physicians champions, nursing support, respiratory therapists, pharmacists, laboratory personnel, and supply chain representatives) to address definitions of normothermia and fever, patient inclusion/exclusion criteria for therapy based on underlying neurorelated pathologies, determination of methods of induction/maintenance, monitoring required, education planning, and strategies to minimize potential complications are warranted.
authors.affiliation: Neuroscience Intensive Care Unit, Thomas Jefferson University Hospital, 111 South 11th Street, Gibbon Building, Room 9300, Philadelphia, PA 19107, USA. Electronic address: Marie.Wilson@jefferson.edu.
authors.forename: Marie
authors.initials: M
authors.lastname: Wilson
authors.affiliation: Neuroscience Intensive Care Unit, Thomas Jefferson University Hospital, 111 South 11th Street, Gibbon Building, Room 9300, Philadelphia, PA 19107, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Della Penna
mesh_terms: D001833:Body Temperature Regulation / Q000502:physiology*; D001930:Brain Injuries / Q000150:complications*; D003299:Cooperative Behavior; D003422:Critical Care; D005334:Fever / Q000209:etiology; D006801:Humans; D007036:Hypothermia, Induced; D007362:Intensive Care Units; D009488:Neurosciences
keywords: Induced hypothermia; Normothermia; Shivering; Targeted temperature management