title: [Effect of laparoscopic surgery under total intravenous anesthesia on postoperative pregnancy outcomes of heterotopic pregnancies].
abstract: OBJECTIVE
  To evaluate the effects of laparoscopic surgery under total intravenous anesthesia (TIVA) on outcomes of heterotopic pregnancies which need to receive laparoscopic procedures.
  
  
  METHODS
  The data of 108 cases of pregnant women in Center of Reproductive Medicine, Peking University Third Hospital were retrospectively analyzed, and divided into two groups according to whether received surgery. Surgery group : 48 pregnant women after in vitro fertilization-embryo transfer (IVF-ET) were diagnosed as heterotopic pregnancies and received laparoscopic procedures under TIVA.
  
  
  METHODS
  60 normal pregnant women after IVF-ET. The miscarriage rate, pregnant complications rate, premature birth rate, live birth rate, delivery weeks and cesarean section rate of two groups were compared. Meanwhile, the newborn's weight, male rate, birth defect rate and Apgar score in 1 min and 5 min of the two groups were compared.
  
  
  RESULTS
  The miscarriage rate, pregnant complications rate, premature birth rate, cesarean section rate, male rate of surgery group were 14.6%, 16.7%, 4.2%, 82.9%, 51.2% respectively, which were 15.0%, 18.3%, 6.7%, 84.3%, 52.9% in control group respectively. There were no significant difference between the two groups (χ(2)=-0.072, -0.241, -0.569, -0.442, -0.163, P>0.05). The delivery weeks and newborn's weight of surgery group were (38.3±1.7)weeks and(3 394.9±460.7)g respectively , which were (37.9±1.5) weeks and (3 406.3±512.6 )g in control group. There were no significant difference between the two groups (t=1.083, -0.111, P>0.05). The 1 min Apgar score and 5 min Apgar score of surgery group were 9.6(9.0-10.0), 10(10-10) scores and were 9.5(9.0-10.0), 10(10-10) scores in control group.There were no significant difference between the two groups (Z=-0.418, 0.000, P>0.05). The live birth rate of two groups were both 100%, and the birth defect rate were both 0.
  
  
  CONCLUSIONS
  Laparoscopic surgery under TIVA has no effect on the outcome of heterotopic pregnancies.
authors.affiliation: Department of Anesthesiology, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Chengmei
authors.initials: C
authors.lastname: Shi
authors.forename: Donglin
authors.initials: D
authors.lastname: Jia
authors.forename: Xueling
authors.initials: X
authors.lastname: Song
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Guo
authors.forename: Chen
authors.initials: C
authors.lastname: Li
mesh_terms: D000022:Abortion, Spontaneous; D000771:Anesthesia, Intravenous; D000773:Anesthesia, Obstetrical; D002585:Cesarean Section; D036861:Delivery, Obstetric; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010535:Laparoscopy; D008297:Male; D011184:Postoperative Period; D011247:Pregnancy; D011256:Pregnancy Outcome; D063192:Pregnancy, Heterotopic; D047928:Premature Birth; D012189:Retrospective Studies