title: A rare case: Hallucination associated with pazopanib.
abstract: Diarrhea, hyperglycemia, anemia, depigmentation of the hair, and rash are common side effects of tyrosine kinase inhibitors. Neurological side effect like hallucination due to pazopanib is exceptionally rare in literature cases. Herein, we reported a case of hallucination related to pazopanib in a patient with renal cell carcinoma. A 47-year-old male patient with renal cell carcinoma developed repetitive hallucinations on the following days of pazopanib initiation. There was no other significant finding in the differential diagnosis of hallucination. Neurological symptoms disappeared after termination of pazopanib. We aimed to emphasize that neurological side effect like hallucination may rarely occur during the treatment of pazopanib and take note that physicians should be aware of this infrequent side effect in the patients treated with pazopanib.
authors.forename: Nebi Serkan
authors.initials: NS
authors.lastname: Demirci
authors.affiliation: Department of Medical Oncology, Ankara Numune Training and Research Hospital, Ankara, Turkey.
authors.forename: Gokmen Umut
authors.initials: GU
authors.lastname: Erdem
authors.forename: Mutlu
authors.initials: M
authors.lastname: Dogan
authors.forename: Nuriye Yıldırım
authors.initials: NY
authors.lastname: Ozdemir
authors.forename: Nurullah
authors.initials: N
authors.lastname: Zengin
mesh_terms: D020533:Angiogenesis Inhibitors / Q000009:adverse effects*; D002292:Carcinoma, Renal Cell / Q000188:drug therapy*; D006212:Hallucinations / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D007191:Indazoles; D007680:Kidney Neoplasms / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011743:Pyrimidines / Q000009:adverse effects*; D013449:Sulfonamides / Q000009:adverse effects*
chemical_list: D020533:Angiogenesis Inhibitors; D007191:Indazoles; D011743:Pyrimidines; D013449:Sulfonamides; C516667:pazopanib