title: Cytochalasans and Sesquiterpenes from Eutypella scoparia 1-15.
abstract: Three new compounds, an open-chain cytochalasan scoparasin C (1), a pyrichalasan scoparasin D (2), and a β-eudesmol type sesquiterpene scopararane C (5), along with three known compounds (3, 4 and 6), were isolated from the marine fungus Eutypella scoparia 1-15. Their structures were determined on the basis of comprehensive NMR and MS analysis. Compound 2 exhibited potent cytotoxicities with very low IC50 values against several cancer cell lines, including A375, A549, HepG2 and MCF-7.
authors.forename: Shuang
authors.initials: S
authors.lastname: Qi
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhonghui
authors.initials: Z
authors.lastname: Zheng
authors.forename: Qingyan
authors.initials: Q
authors.lastname: Xu
authors.forename: Xianming
authors.initials: X
authors.lastname: Deng
mesh_terms: D001203:Ascomycota / Q000737:chemistry*; D003572:Cytochalasins / Q000737:chemistry*; D008958:Models, Molecular; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*
chemical_list: D003572:Cytochalasins; D012717:Sesquiterpenes