title: Lattice engineering through nanoparticle-DNA frameworks.
abstract: Advances in self-assembly over the past decade have demonstrated that nano- and microscale particles can be organized into a large diversity of ordered three-dimensional (3D) lattices. However, the ability to generate different desired lattice types from the same set of particles remains challenging. Here, we show that nanoparticles can be assembled into crystalline and open 3D frameworks by connecting them through designed DNA-based polyhedral frames. The geometrical shapes of the frames, combined with the DNA-assisted binding properties of their vertices, facilitate the well-defined topological connections between particles in accordance with frame geometry. With this strategy, different crystallographic lattices using the same particles can be assembled by introduction of the corresponding DNA polyhedral frames. This approach should facilitate the rational assembly of nanoscale lattices through the design of the unit cell.
authors.affiliation: Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Ye
authors.initials: Y
authors.lastname: Tian
authors.affiliation: Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Yugang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Biosciences Department, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Tong
authors.initials: T
authors.lastname: Wang
authors.affiliation: Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Huolin L
authors.identifier: 0000-0002-6521-868X
authors.initials: HL
authors.lastname: Xin
authors.affiliation: Biosciences Department, Brookhaven National Laboratory, Upton, New York 11973, USA.|Department of Biochemistry and Cell Biology, Stony Brook University, Stony Brook, New York 11794, USA.
authors.forename: Huilin
authors.initials: H
authors.lastname: Li
authors.affiliation: Center for Functional Nanomaterials, Brookhaven National Laboratory, Upton, New York 11973, USA.
authors.forename: Oleg
authors.initials: O
authors.lastname: Gang
mesh_terms: D017104:Bacteriophage M13 / Q000737:chemistry* / Q000235:genetics; D004279:DNA, Viral / Q000737:chemistry* / Q000235:genetics; D006046:Gold / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*
chemical_list: D004279:DNA, Viral; D006046:Gold