title: Effects of bisphenol-A on male reproductive success in adult Kadaknath chicken.
abstract: Bisphenol-A (BPA) adversely affects human and animal reproductive success in many ways, but this information is scant on birds. In the present study, we investigated the reproductive toxicity of BPA in adult Kadaknath chicken using two BPA dosages orally (1 or 5 mg/kg body weight) for seven weeks. In order to assess BPA toxicity, sperm functions, fertilizing ability, serum testosterone concentration and testis histopathology were measured in treated and control chickens. The semen volume was highest in birds exposed to 1mg/kg body weight BPA compared to other groups. 5 mg/kg body weight BPA reduced sperm concentration significantly more than other treatment and controls. However, overall fertility and testis histology were unaffected. These results indicate that BPA adversely affects sperm characteristics in adult kadaknath chicken without affecting fertilization potential.
authors.affiliation: Avian Physiology and Genetics Division, Sálim Ali Centre for Ornithology and Natural History, Anaikatty, 641108 Coimbatore, India. Electronic address: rampratapsingh81@gmail.com.
authors.forename: Ram P
authors.initials: RP
authors.lastname: Singh
authors.affiliation: Avian Physiology and Genetics Division, Sálim Ali Centre for Ornithology and Natural History, Anaikatty, 641108 Coimbatore, India.
authors.forename: Chathathayil M
authors.initials: CM
authors.lastname: Shafeeque
authors.affiliation: Central Avian Research Institute, Izatnagar 243 122, India.
authors.forename: Sanjeev K
authors.initials: SK
authors.lastname: Sharma
authors.affiliation: Indian Veterinary Research Institute, Izatnagar 243 122, India.
authors.forename: Renu
authors.initials: R
authors.lastname: Singh
authors.affiliation: Central Avian Research Institute, Izatnagar 243 122, India.
authors.forename: Maharajan
authors.initials: M
authors.lastname: Kannan
authors.affiliation: Central Avian Research Institute, Izatnagar 243 122, India.
authors.forename: Kochiganti V H
authors.initials: KV
authors.lastname: Sastry
authors.affiliation: Rajiv Gandhi Centre for Biotechnology, Thycaud P.O., Thiruvananthapuram 695 014, India.
authors.forename: Sajith
authors.initials: S
authors.lastname: Raghunandanan
authors.affiliation: Central Avian Research Institute, Izatnagar 243 122, India.
authors.forename: Jag
authors.initials: J
authors.lastname: Mohan
authors.affiliation: Avian Physiology and Genetics Division, Sálim Ali Centre for Ornithology and Natural History, Anaikatty, 641108 Coimbatore, India.
authors.forename: Parappurath A
authors.initials: PA
authors.lastname: Azeez
mesh_terms: D000818:Animals; D001559:Benzhydryl Compounds / Q000633:toxicity*; D002645:Chickens / Q000033:anatomy & histology / Q000097:blood / Q000502:physiology*; D005260:Female; D005298:Fertility / Q000187:drug effects; D008297:Male; D010636:Phenols / Q000633:toxicity*; D012098:Reproduction / Q000187:drug effects*; D013094:Spermatozoa / Q000187:drug effects*; D013737:Testis / Q000033:anatomy & histology / Q000187:drug effects; D013739:Testosterone / Q000097:blood; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D010636:Phenols; D013739:Testosterone; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Bisphenol-A; Fertility; Reproductive toxicity; Semen; Testosterone