title: Utility of Patient-Reported Outcome Instruments in Heart Failure.
abstract: Patient-reported outcomes (PRO) are defined as reports coming directly from patients about how they feel or function in relation to a health condition and its therapy. Although there are numerous compelling reasons why PRO could be an important help in clinical care, they have not evolved into clinical tools integrated into care. The purpose of this review is to assess existing PRO instruments for heart failure with respect to their psychometric properties and potential for use in clinical care. We performed a systematic search of articles published between July 2008 and January 2015 within the MEDLINE, PROMIS, PROQOLID, and Cochrane Library databases. Included instruments had to be developed and tested for heart failure and have had their development processes and psychometric properties described. A total of 31 instruments were identified, 9 of which met all inclusion criteria. After evaluating each remaining instrument in terms of psychometric and clinical criteria and symptom coverage, only 2 instruments-Minnesota Living with Heart Failure and Kansas City Cardiomyopathy questionnaire-met all evaluation criteria. Although clinically useful PRO instruments exist, increasing education to providers on the value and interpretability of PRO instruments, as well as a more streamlined approach to their implementation in the clinical setting is necessary. A clinical trial comparing the routine use of disease-specific PRO with clinical care could further support their incorporation into practice.
authors.affiliation: Cardiology Division, Emory University, Atlanta, Georgia.
authors.forename: Anita A
authors.initials: AA
authors.lastname: Kelkar
authors.affiliation: Health Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.
authors.forename: John
authors.initials: J
authors.lastname: Spertus
authors.affiliation: Department of Emergency Medicine, Indiana University, Indianapolis, Indiana.
authors.forename: Peter
authors.initials: P
authors.lastname: Pang
authors.affiliation: Patient Reported Outcomes, Janssen Pharmaceutical Companies of Johnson & Johnson.
authors.forename: Renee F
authors.initials: RF
authors.lastname: Pierson
authors.affiliation: Patient Reported Outcomes, Janssen Pharmaceutical Companies of Johnson & Johnson.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Cody
authors.affiliation: Division of Cardiology, Montefiore Medical Center, Bronx, New York.
authors.forename: Ileana L
authors.initials: IL
authors.lastname: Pina
authors.affiliation: Department of Cardiology, Duke University, Durham, North Carolina.
authors.forename: Adrian
authors.initials: A
authors.lastname: Hernandez
authors.affiliation: Cardiology Division, Stony Brook University, Stony Brook, New York. Electronic address: javed.butler@stonybrookmedicine.edu.
authors.forename: Javed
authors.initials: J
authors.lastname: Butler
mesh_terms: D002986:Clinical Trials as Topic; D006333:Heart Failure / Q000628:therapy*; D006801:Humans; D000071066:Patient Reported Outcome Measures; D011594:Psychometrics; D011795:Surveys and Questionnaires
keywords: heart failure; patient-reported outcomes