title: Stage I posterior osteotomy and instrumentation and stage II anterior debridement and bone grafting for lumbar spinal tuberculosis with severe kyphosis.
abstract: The purpose of this study was to determine the efficacy of stage I posterior osteotomy and instrumentation followed by stage II anterior debridement and bone grafting in patients with lumbar spinal tuberculosis (TB) with severe kyphosis. The records of patients with lumbar spinal TB and severe kyphosis treated with 2-stage surgery at our hospital from 2005 to 2010 were retrospectively reviewed. Outcome measures were kyphosis correction rate, visual analogue scale (VAS) pain scores, and American Spinal Injury Association (ASIA) spinal cord injury and sensation function scores. A total of 53 patients (34 male, 19 female; mean age 32 years) were included. The number of involved kyphosis segments ranged from 7 to 14, and the average preoperative kyphosis angle was 107.3 ± 18.1°. All procedures were performed without serious complications. The average follow-up time was 42 months. Bone fusion occurred at a range of 6 to 9 months after surgery, and none of the patients had internal fixation failure, position change, or pseudoarthrosis. The mean postoperative kyphosis angle was 29.4 ± 12.4°, with a mean improvement of 77.9°, and the correction rate was 72.6% (P < 0.001). At final follow-up, average correction loss was 1.35°. The mean postoperative VAS pain score was 2.4 ± 0.8, and the change from the preoperative value was significant (P < 0.001). ASIA spinal injury scores were increased postoperatively. Stage I posterior osteotomy and instrumentation followed by stage II anterior debridement and bone grafting can achieve good results in patients with lumbar TB and severe kyphosis.
authors.affiliation: Department of Spinal Surgery, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830054, Xinjiang, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Deng
authors.affiliation: Department of Histology & Embryology, Preclinical Institute, Xinjiang Medical University Urumqi 830011, China.
authors.forename: Yalou
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Spinal Surgery, The First Affiliated Hospital of Xinjiang Medical University Urumqi 830054, Xinjiang, China.
authors.forename: Weibin
authors.initials: W
authors.lastname: Sheng
keywords: Spinal tuberculosis; bone grafting; clinical efficacy; kyphosis; osteotomy