title: Manifestations of bodily isomerism.
abstract: We report the findings present in 49 postmortem specimens from patients with so-called heterotaxy, concentrating on those found in the extracardiac systems of organs. Also known as bodily isomerism, we suggest that it is important to segregate the syndromes into their isomeric subtypes to be able to make inferences regarding likely extracardiac and intracardiac findings to allow for proper surveillance. We demonstrate that this is best done on the basis of the atrial appendages, which were isomeric in all the hearts obtained from the specimens available for our inspection. The abdominal organs do not demonstrate isomerism, and they show variable features when compared to the isomeric atrial appendages.
authors.affiliation: Children's Hospital of Wisconsin, Medical College of Wisconsin, 9000 Wisconsin Avenue, Milwaukee, WI. Electronic address: loomba.rohit@gmail.com.
authors.forename: Rohit S
authors.initials: RS
authors.lastname: Loomba
authors.affiliation: Ziauddin University, 4/B, Shahrah-e-Ghalib, Block 6, Clifton, Karachi, 75600, Pakistan.
authors.forename: Muhammad M
authors.initials: MM
authors.lastname: Ahmed
authors.affiliation: University of Florida Department of Pediatric Cardiology, 1600 SW Archer Road, Gainesville, FL; Johns Hopkins All Children's Heart Institute, 501 6th Avenue, St. Petersburg, FL.
authors.forename: Diane E
authors.initials: DE
authors.lastname: Spicer
authors.affiliation: Lurie Children's Hospital, Feinberg School of Medicine, 225 E Chicago Avenue, Chicago, IL.
authors.forename: Carl L
authors.initials: CL
authors.lastname: Backer
authors.affiliation: Institute of Genetic Medicine, Newcastle University, Central Parkway, Newcastle upon Tyne, Tyne and Wear NE1 3BZ, United Kingdom.
authors.forename: Robert H
authors.initials: RH
authors.lastname: Anderson
mesh_terms: D001344:Autopsy; D005260:Female; D006330:Heart Defects, Congenital / Q000473:pathology*; D059446:Heterotaxy Syndrome / Q000473:pathology*; D006801:Humans; D008297:Male
keywords: Bronchial; Heterotaxy; Hydrocephalus; Infection; Isomerism; Spleen