title: Women's views on autologous cell-based therapy for post-obstetric incontinence.
abstract: OBJECTIVE
  Fecal and urinary incontinence are devastating consequences of obstetric-related perineal injury. The aim of the present study is to determine acceptability to parous women of autologous cell-based therapy for fecal and urinary incontinence that arises due to pelvic diaphragm tearing during vaginal childbirth.
  
  
  METHODS
  A multiple choice questionnaire survey was offered to 76 parous women at the Maternity Unit, University College Hospital, London, UK. Seventy completed questionnaires - response rate: 92%.
  
  
  RESULTS
  In total, 84% of women indicated a willingness to accept autologous cell-based therapy for obstetric injury-induced incontinence rather than surgery.
  
  
  CONCLUSIONS
  These observational data provide an indication of likely acceptance of autologous cell-based therapies for birth injury incontinence and will help with designing new therapeutic approaches.
authors.affiliation: Applied Biomedical Engineering Group, University College London, Rockefeller Building, 21 University Street, London, WC1E 6JJ, UK.
authors.forename: Bernice
authors.initials: B
authors.lastname: Wright
authors.affiliation: GI Physiology Unit, University College Hospital, 235 Euston Road, London, NW1 2BU, UK.
authors.forename: Anton
authors.initials: A
authors.lastname: Emmanuel
authors.affiliation: GI Physiology Unit, University College Hospital, 235 Euston Road, London, NW1 2BU, UK.
authors.forename: Eleni
authors.initials: E
authors.lastname: Athanasakos
authors.affiliation: Applied Biomedical Engineering Group, University College London, Rockefeller Building, 21 University Street, London, WC1E 6JJ, UK.
authors.forename: Nina
authors.initials: N
authors.lastname: Parmar
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Georgina
authors.initials: G
authors.lastname: Parker
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Belinda
authors.initials: B
authors.lastname: Green
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Emma
authors.initials: E
authors.lastname: Tailby
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Heidi
authors.initials: H
authors.lastname: Chandler
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Julyette
authors.initials: J
authors.lastname: Cushnie
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: June
authors.initials: J
authors.lastname: Pembroke
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Yvonne
authors.initials: Y
authors.lastname: Saruchera
authors.affiliation: University College Hospital, Elizabeth Garrett Anderson Wing, Institute for Women's Health, London, WC1E 6BD, UK.
authors.forename: Arvind
authors.initials: A
authors.lastname: Vashisht
authors.affiliation: Applied Biomedical Engineering Group, University College London, Rockefeller Building, 21 University Street, London, WC1E 6JJ, UK.
authors.forename: Richard
authors.initials: R
authors.lastname: Day
mesh_terms: D000328:Adult; D001294:Attitude to Health; D064592:Autografts; D064987:Cell- and Tissue-Based Therapy; D005242:Fecal Incontinence / Q000209:etiology / Q000628:therapy*; D005260:Female; D006801:Humans; D049590:Postpartum Period; D011795:Surveys and Questionnaires; D014549:Urinary Incontinence / Q000209:etiology / Q000628:therapy*
keywords: anal sphincter; autologous stem cell therapy; fecal incontinence; obstetric injury; patient preference; urinary incontinence