title: Association of thiol disulfide homeostasis with slow coronary flow.
abstract: Objective The aim of this study was to investigate the role of thiol disulfide homeostasis in the presence of slow coronary flow. Material and methods In this cross-sectional study, a total of 110 patients who admitted to our hospital between March 2014 and December 2015 were included in the study. There were 65 patients in the slow coronary flow, and 45 patients in the normal flow groups. Results We found significant differences between slow coronary flow and the normal flow groups for thiol disulfide homeostasis, and the results of our study indicated that hsCRP, and thiol disulfide ratio were independently associated with slow coronary flow. Conclusion Our study showed that thiol disulfide homeostasis was significantly and independently related to the presence of slow coronary flow.
authors.affiliation: a Department of Cardiology , Ankara Numune Education and Research Hospital , Ankara , Turkey ;
authors.forename: Harun
authors.initials: H
authors.lastname: Kundi
authors.affiliation: a Department of Cardiology , Ankara Numune Education and Research Hospital , Ankara , Turkey ;
authors.forename: Murat
authors.initials: M
authors.lastname: Gok
authors.affiliation: a Department of Cardiology , Ankara Numune Education and Research Hospital , Ankara , Turkey ;
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cetin
authors.affiliation: a Department of Cardiology , Ankara Numune Education and Research Hospital , Ankara , Turkey ;
authors.forename: Emrullah
authors.initials: E
authors.lastname: Kiziltunç
authors.affiliation: b Department of Biochemistry , Ankara Numune Education and Research Hospital , Ankara , Turkey ;
authors.forename: Canan
authors.initials: C
authors.lastname: Topcuoglu
authors.affiliation: c Department of Biochemistry , Yildirim Beyazit University Medical Faculty , Ankara , Turkey.
authors.forename: Salim
authors.initials: S
authors.lastname: Neşelioğlu
authors.affiliation: c Department of Biochemistry , Yildirim Beyazit University Medical Faculty , Ankara , Turkey.
authors.forename: Ozcan
authors.initials: O
authors.lastname: Erel
authors.affiliation: a Department of Cardiology , Ankara Numune Education and Research Hospital , Ankara , Turkey ;
authors.forename: Feridun Vasfi
authors.initials: FV
authors.lastname: Ulusoy
mesh_terms: D000328:Adult; D000368:Aged; D060050:Angina, Stable / Q000175:diagnosis / Q000378:metabolism; D017023:Coronary Angiography / Q000379:methods*; D003326:Coronary Circulation; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000378:metabolism / Q000503:physiopathology; D004220:Disulfides; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018384:Oxidative Stress / Q000502:physiology*; D013223:Statistics as Topic; D013438:Sulfhydryl Compounds / Q000378:metabolism*
chemical_list: D004220:Disulfides; D013438:Sulfhydryl Compounds
keywords: Oxidative stress; slow coronary flow; thiol disulfide homeostasis