title: mRNA biogenesis-related helicase eIF4AIII from Arabidopsis thaliana is an important factor for abiotic stress adaptation.
abstract: Similar to other plant species, Arabidopsis has a huge repertoire of predicted helicases, including the eIF4AIII factor, a putative component of the exon junction complex related to mRNA biogenesis. In this article, we integrated evolutionary and functional approaches to have a better understanding of eIF4AIII function in plants. Phylogenetic analysis showed that the mRNA biogenesis-related helicase eIF4AIII is the ortholog of the stress-related helicases PDH45 from Pisum sativum and MH1 from Medicago sativa, suggesting evolutionary and probably functional equivalences between mRNA biogenesis and stress-related plant helicases. Molecular and genetic analyses confirmed the relevance of eIF4AIII during abiotic stress adaptation in Arabidopsis. Therefore, in addition to its function in mRNA biogenesis, eIF4AIII can play a role in abiotic stress adaptation.
authors.affiliation: CONICET, Avda. Rivadavia 1917, C1033AAJ CABA, Buenos Aires, Argentina.|IGEAF- INTA, De los reseros S/N, Castelar C25 (1712), Buenos Aires, Argentina.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Pascuan
authors.affiliation: CONICET, Avda. Rivadavia 1917, C1033AAJ CABA, Buenos Aires, Argentina.
authors.forename: Romina
authors.initials: R
authors.lastname: Frare
authors.affiliation: CONICET, Avda. Rivadavia 1917, C1033AAJ CABA, Buenos Aires, Argentina.
authors.forename: Karina
authors.initials: K
authors.lastname: Alleva
authors.affiliation: CONICET, Avda. Rivadavia 1917, C1033AAJ CABA, Buenos Aires, Argentina.|IGEAF- INTA, De los reseros S/N, Castelar C25 (1712), Buenos Aires, Argentina.
authors.forename: Nicolás Daniel
authors.initials: ND
authors.lastname: Ayub
authors.affiliation: CONICET, Avda. Rivadavia 1917, C1033AAJ CABA, Buenos Aires, Argentina. soto.gabrielacinthia@inta.gob.ar.|IGEAF- INTA, De los reseros S/N, Castelar C25 (1712), Buenos Aires, Argentina. soto.gabrielacinthia@inta.gob.ar.
authors.forename: Gabriela
authors.identifier: http://orcid.org/0000-0002-3492-1268
authors.initials: G
authors.lastname: Soto
mesh_terms: D000222:Adaptation, Physiological; D017360:Arabidopsis / Q000201:enzymology* / Q000235:genetics / Q000502:physiology; D039601:Eukaryotic Initiation Factor-4A / Q000235:genetics / Q000378:metabolism*; D005091:Exons / Q000235:genetics; D010802:Phylogeny; D020365:RNA Helicases / Q000235:genetics / Q000378:metabolism; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D018749:RNA, Plant / Q000235:genetics / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D012333:RNA, Messenger; D018749:RNA, Plant; D039601:Eukaryotic Initiation Factor-4A; D020365:RNA Helicases
keywords: Abiotic stress; Arabidopsis; Evolution; Helicases; mRNA biogenesis