title: Potential of APDM mobility lab for the monitoring of the progression of Parkinson's disease.
abstract: APDM's Mobility Lab system provides portable, validated, reliable, objective measures of balance and gait that are sensitive to Parkinson's disease (PD). In this review, we describe the potential of objective measures collected with the Mobility Lab system for tracking longitudinal progression of PD. Balance and gait are among the most important motor impairments influencing quality of life for people with PD. Mobility Lab uses body-worn, Opal sensors on the legs, trunk and arms during prescribed tasks, such as the instrumented Get Up and Go test or quiet stance, to quickly quantify the quality of balance and gait in the clinical environment. The same Opal sensors can be sent home with patients to continuously monitor the quality of their daily activities. Objective measures have the potential to monitor progression of mobility impairments in PD throughout its course to improve patient care and accelerate clinical trials.
authors.affiliation: a Veterans Affairs Portland Healthcare System (VAPORHCS) , Portland , OR , USA.|b Department of Neurology , Oregon Health & Science University , Portland , OR , USA.
authors.forename: Martina
authors.initials: M
authors.lastname: Mancini
authors.affiliation: a Veterans Affairs Portland Healthcare System (VAPORHCS) , Portland , OR , USA.|b Department of Neurology , Oregon Health & Science University , Portland , OR , USA.
authors.forename: Fay B
authors.initials: FB
authors.lastname: Horak
mesh_terms: D018450:Disease Progression; D005684:Gait / Q000502:physiology; D006801:Humans; D018670:Monitoring, Ambulatory / Q000379:methods*; D009068:Movement / Q000502:physiology*; D010300:Parkinson Disease / Q000473:pathology* / Q000503:physiopathology*; D004856:Postural Balance / Q000502:physiology
keywords: Mobility; Parkinson’s disease; inertial sensors; mobility lab; objective measures