title: Biologic resurfacing arthroplasty with acellular human dermal allograft and platelet-rich plasma (PRP) in young patients with glenohumeral arthritis-average of 60 months of at mid-term follow-up.
abstract: BACKGROUND
  The treatment of young patients with glenohumeral arthritis has been challenging. Alternative treatment options include activity modification, arthroscopic débridement, and arthroplasty. Addressing the glenoid during arthroplasty in this population of patients continues to be a significant challenge. In this study, we evaluated the midterm outcomes of hemiarthroplasty with biologic resurfacing of the glenoid with human dermal matrix allograft.
  
  
  METHODS
  Between 2004 and 2011, 55 patients underwent hemiarthroplasty and biologic resurfacing of the glenoid with human dermal matrix allograft. The average age was 50 ± 9 years. Subjective evaluation was performed with the Western Ontario Osteoarthritis of the Shoulder Index, American Shoulder and Elbow Surgeons score, visual analog scale, and Single Assessment Numeric Evaluation. Patients returned to the clinic for clinical examination and radiographic evaluation. The average follow-up was 60 months.
  
  
  RESULTS
  The average postoperative American Shoulder and Elbow Surgeons score was 76 ± 22, and the Western Ontario Osteoarthritis of the Shoulder Index score was 76% ± 22%. The visual analog scale score was 2.4 ± 2.6. The average preoperative Single Assessment Numeric Evaluation score was 33% ± 22%, which significantly improved to 72% ± 22% postoperatively. Eighty-one percent of the patients were satisfied (10/47) or highly satisfied (28/47) with their result. With radiographic evaluation, the average joint space was 1 ± 1 mm preoperatively and 2 ± 1 mm postoperatively. A total of 5 cases (9.1%) were revised to anatomic total shoulder arthroplasty with implantation of a glenoid component.
  
  
  CONCLUSIONS
  Hemiarthroplasty with biologic resurfacing of the glenoid using human dermal matrix allograft can lead to successful midterm outcomes with satisfactory complication and revision rates. Both patient satisfaction and clinical outcome remain high regardless of radiographic outcome.
authors.affiliation: Center of Sports Medicine, St. Francis Memorial Hospital, San Francisco, CA, USA. Electronic address: Eddielomd@gmail.com.
authors.forename: Eddie Y
authors.initials: EY
authors.lastname: Lo
authors.affiliation: The Shoulder Center at Baylor University Medical Center, Dallas, TX, USA.
authors.forename: Brody A
authors.initials: BA
authors.lastname: Flanagin
authors.affiliation: WB Carrell Memorial Clinic, Dallas, TX, USA.
authors.forename: Wayne Z
authors.initials: WZ
authors.lastname: Burkhead
mesh_terms: D062088:Acellular Dermis; D000328:Adult; D000368:Aged; D000072228:Arthroplasty, Replacement, Shoulder; D005500:Follow-Up Studies; D061165:Glenoid Cavity / Q000601:surgery*; D062785:Hemiarthroplasty / Q000379:methods*; D006801:Humans; D008875:Middle Aged; D010003:Osteoarthritis / Q000503:physiopathology / Q000601:surgery*; D017060:Patient Satisfaction; D053657:Platelet-Rich Plasma; D016059:Range of Motion, Articular; D012086:Reoperation; D012785:Shoulder Joint / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Glenohumeral arthritis; biologic resurfacing; human dermal matrix allograft; platelet rich plasma; shoulder arthroplasty; young patients