title: Organo-Iodine(III)-Catalyzed Oxidative Phenol-Arene and Phenol-Phenol Cross-Coupling Reaction.
abstract: The direct oxidative coupling reaction has been an attractive tool for environmentally benign chemistry. Reported herein is that the hypervalent iodine catalyzed oxidative metal-free cross-coupling reaction of phenols can be achieved using Oxone as a terminal oxidant in 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP). This method features a high efficiency and regioselectivity, as well as functional-group tolerance under very mild reaction conditions without using metal catalysts.
authors.affiliation: Ritsumeikan University, College of Pharmaceutical Sciences, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.|Research Organization of Science and Technology, Ritsumeikan University, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Morimoto
authors.affiliation: Ritsumeikan University, College of Pharmaceutical Sciences, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Sakamoto
authors.affiliation: Ritsumeikan University, College of Pharmaceutical Sciences, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Ohshika
authors.affiliation: Ritsumeikan University, College of Pharmaceutical Sciences, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Dohi
authors.affiliation: Ritsumeikan University, College of Pharmaceutical Sciences, 1-1-1 Nojihigashi, Kusatsu, Shiga, 525-8577, Japan. kita@ph.ritsumei.ac.jp.|Research Organization of Science and Technology, Ritsumeikan University, Japan. kita@ph.ritsumei.ac.jp.
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kita
keywords: biaryls; cross-coupling; homogenous catalysis; iodine; oxidation