title: Native Tissue Prolapse Repairs: Comparative Effectiveness Trials.
abstract: This report reviews the success rates and complications of native tissue (nonmesh) vaginal reconstruction of pelvic organ prolapse by compartment. For apical prolapse, both uterosacral ligament suspensions and sacrospinous ligament fixations are effective and provided similar outcomes in anatomy and function with few adverse events. In the anterior compartment, traditional colporrhaphy technique is no different than ultralateral suturing. In the posterior compartment, transvaginal rectocele repair is superior to transanal repair. For uterine preservation, sacrospinous hysteropexy is not inferior to vaginal hysterectomy with uterosacral ligament suspension for treatment of apical uterovaginal prolapse.
authors.affiliation: Center for Urogynecology and Reconstructive Pelvic Surgery, Obstetrics, Gynecology & Women's Health Institute, Cleveland Clinic, 9500 Euclid Avenue A81, Cleveland, OH 44195, USA. Electronic address: siffl@ccf.org.
authors.forename: Lauren N
authors.initials: LN
authors.lastname: Siff
authors.affiliation: Center for Urogynecology and Reconstructive Pelvic Surgery, Obstetrics, Gynecology & Women's Health Institute, Cleveland Clinic, 9500 Euclid Avenue A81, Cleveland, OH 44195, USA.
authors.forename: Matthew D
authors.initials: MD
authors.lastname: Barber
mesh_terms: D002986:Clinical Trials as Topic; D057186:Comparative Effectiveness Research; D005260:Female; D006801:Humans; D008022:Ligaments / Q000601:surgery; D056887:Pelvic Organ Prolapse / Q000601:surgery*; D014599:Uterus / Q000601:surgery; D014621:Vagina / Q000601:surgery
keywords: Anterior colporrhaphy; Colpopexy; Native-tissue pelvic organ prolapse repair; Pelvic organ prolapse; Posterior colporrhaphy; Sacrospinous ligament fixation; Uterosacral ligament suspension; Vaginal reconstruction