title: Hypertension on admission is associated with a lower risk of early seizures after stroke.
abstract: OBJECTIVE
  Despite the common occurrence of early seizures (ES) after stroke, the relationship between risk factors and this complication of stroke is not well established. In this study we have examined the relationship between clinical measures on admission and ES after stroke.
  
  
  METHODS
  We included 1073 patients (mean age 69 ± 12, 51.6% females) with ischemic and haemorrhagic stroke. The frequency of seizure occurrence within 2 weeks of stroke was determined. We used a logistic regression model to analyse the effect of blood pressure on admission and other clinical factors (age, gender, diabetes, atrial fibrillation and dyslipidemia) on the occurrence of ES after stroke.
  
  
  RESULTS
  ES occurred after 4.1% and 4.0% of ischemic and haemorrhagic strokes respectively. Compared to patients with high blood pressure on admission, those with low and normal blood pressure had a higher risk of ES after stroke (2.9% vs.7.5% vs. 7.6%, p=0.001). Also the mean age of patients with post-stroke ES was lower (62.5 vs. 69.3, p<0.001). In a logistic regression analysis, low/normal blood pressure remained independently associated with ES after stroke with OR of 2.46 (95% CI 1.38-4.63, p=0.006).
  
  
  CONCLUSIONS
  ES after stroke was equally frequent in patients with ischemic and haemorrhagic stroke. Low/normal blood pressure on admission and younger patient age were risk factors for ES after stroke.
authors.affiliation: Department of Neurology, University Clinical Center of Kosovo, Pristina, Kosovo; Department of Neurology, University of Pristina, Pristina, Kosovo.
authors.forename: Zylfije
authors.initials: Z
authors.lastname: Hundozi
authors.affiliation: Department of Neurology, University Clinical Center of Kosovo, Pristina, Kosovo; Department of Neurology, University of Pristina, Pristina, Kosovo.
authors.forename: Argjend
authors.initials: A
authors.lastname: Shala
authors.affiliation: Department of Neurology, University Clinical Center of Kosovo, Pristina, Kosovo.
authors.forename: Dren
authors.initials: D
authors.lastname: Boshnjaku
authors.affiliation: Department of Histology, University of Pristina, Pristina, Kosovo.
authors.forename: Samir
authors.initials: S
authors.lastname: Bytyqi
authors.affiliation: Department of Neurology, University Clinical Center of Kosovo, Pristina, Kosovo; Department of Neurology, University of Pristina, Pristina, Kosovo.
authors.forename: Jehona
authors.initials: J
authors.lastname: Rrustemi
authors.affiliation: Department of Neurology, University Clinical Center of Kosovo, Pristina, Kosovo.
authors.forename: Muhamed
authors.initials: M
authors.lastname: Rama
authors.affiliation: Department of Neurology, University Clinical Center of Kosovo, Pristina, Kosovo; Department of Histology, University of Pristina, Pristina, Kosovo. Electronic address: fisnik.jashari@midicin.umu.se.
authors.forename: Fisnik
authors.initials: F
authors.lastname: Jashari
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology*; D016009:Chi-Square Distribution; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications* / Q000000981:diagnostic imaging; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D059906:Neuroimaging; D012189:Retrospective Studies; D012307:Risk Factors; D012640:Seizures / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D020521:Stroke / Q000145:classification / Q000150:complications* / Q000000981:diagnostic imaging / Q000453:epidemiology
keywords: Early seizures; Hypertension; Risk factors; Stroke