title: RELATIONSHIP BETWEEN RADIATION DOSE AND IMAGE QUALITY IN DIGITAL BREAST TOMOSYNTHESIS.
abstract: This phantom-based study aimed to examine radiation dose from digital breast tomosynthesis (DBT) and digital mammography (DM) and to assess the potential for dose reductions for each modality. Images were acquired at 10-60 mm thicknesses and four dose levels and mean glandular dose was determined using a solid-state dosemeter. Eleven readers assessed image quality and compared simulated lesions with those on a reference image, and the data produced was analysed with the Friedman and Wilcoxon signed-rank tests. For a phantom thickness of 50 mm (typical breast thickness), DBT dose was 13 % higher than DM, but this differential is highly dependent on thickness. Visibility of masses was equal to a reference image (produced at 100 % dose) when dose was reduced by 75 and 50 % for DBT and DM. For microcalcifications, visibility was comparable with the reference image for both modalities at 50 % dose. This study highlighted the potential for reducing dose with DBT.
authors.affiliation: MIOPeG, Faculty of Health Sciences, University of Sydney, Room M220, 75 East Street Lidcombe, Sydney, NSW 2141, Australia.
authors.forename: Maram M
authors.initials: MM
authors.lastname: Alakhras
authors.affiliation: MIOPeG, Faculty of Health Sciences, University of Sydney, Room M220, 75 East Street Lidcombe, Sydney, NSW 2141, Australia.|Department of Biomedical Informatics and Department of Radiology, University of Pittsburgh School of Medicine, Pittsburgh, USA.
authors.forename: Claudia
authors.initials: C
authors.lastname: Mello-Thoms
authors.affiliation: MIOPeG, Faculty of Health Sciences, University of Sydney, Room M220, 75 East Street Lidcombe, Sydney, NSW 2141, Australia.
authors.forename: Roger
authors.initials: R
authors.lastname: Bourne
authors.affiliation: MIOPeG, Faculty of Health Sciences, University of Sydney, Room M220, 75 East Street Lidcombe, Sydney, NSW 2141, Australia.|Sydney Breast Clinic, Sydney, NSW, Australia.
authors.forename: Mary
authors.initials: M
authors.lastname: Rickard
authors.affiliation: John Hunter Hospital, NSW, Australia.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Diffey
authors.affiliation: MIOPeG, Faculty of Health Sciences, University of Sydney, Room M220, 75 East Street Lidcombe, Sydney, NSW 2141, Australia.
authors.forename: Patrick C
authors.initials: PC
authors.lastname: Brennan
mesh_terms: D001940:Breast; D001943:Breast Neoplasms / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008327:Mammography; D019047:Phantoms, Imaging; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement