title: Psychiatric Symptoms in the Initial Motor Stage of Parkinson's Disease.
abstract: Neuropsychiatric symptoms (NPS) are common in Parkinson's disease (PD). The aim of this study was to estimate the correlates of NPS in patients with PD in the initial motor stage of the disease (hemiparkinsonism). A total of 111 patients with PD and 105 healthy control participants were assessed. Patients with PD experienced apathy, depression, and anxiety more frequently compared with healthy controls. Sleep disturbances occurred commonly in early PD patients. Patients with PD and mild cognitive impairment (MCI) had depression and anxiety more frequently, but not apathy, compared with patients with PD without MCI. The results of this study confirm a high burden of NPS even in the earliest motor stage of PD.
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Iva
authors.initials: I
authors.lastname: Stanković
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Elka
authors.initials: E
authors.lastname: Stefanova
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Tomić
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Milica Ječmenica
authors.initials: MJ
authors.lastname: Lukić
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Tanja
authors.initials: T
authors.lastname: Stojković
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Vladana
authors.initials: V
authors.lastname: Marković
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Gorana Mandić
authors.initials: GM
authors.lastname: Stojmenović
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Nikola
authors.initials: N
authors.lastname: Kresojević
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Marina
authors.initials: M
authors.lastname: Svetel
authors.affiliation: From Neurology Clinic, Clinical Center of Serbia, Belgrade, Serbia (IS, ES, AT, MJL, TS, VM, GMS, NK, MS, VK); and School of Medicine, University of Belgrade, Belgrade, Serbia (ES, MS, VK).
authors.forename: Vladimir
authors.initials: V
authors.lastname: Kostić
mesh_terms: D000368:Aged; D001008:Anxiety Disorders / Q000209:etiology; D016022:Case-Control Studies; D003072:Cognition Disorders / Q000209:etiology; D003863:Depression / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D009068:Movement / Q000502:physiology*; D009483:Neuropsychological Tests; D010300:Parkinson Disease / Q000150:complications*; D011569:Psychiatric Status Rating Scales; D012893:Sleep Wake Disorders / Q000209:etiology