title: NGMSElect™ and Investigator(®) Argus X-12 analysis in population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey.
abstract: The analysis of STRs is the main tool when studying genetic diversity in populations or when addressing individual identification in forensic casework. Population data are needed to establish reference databases that can be used in the forensic context. To that end, this work investigated five population samples from Albania, Iraq, Lithuania, Slovenia, and Turkey. Individuals were typed for 16 autosomal STRs and 12 X-chromosomal STRs using the NGMSElect™ and Investigator(®) Argus X-12 kits, respectively. The aim of the study was to characterize the diversity of both STR kits in these population samples and to expand our forensic database. The results showed that all markers were polymorphic in the five populations studied. No haplotype was shared between the males analysed for X-STRs. No statistically significant deviations from Hardy-Weinberg equilibrium were observed for any of the genetic markers included in both the kits. Pairwise LD was only detected in X-STRs between markers located in the same linkage group. Power of discrimination values for males and females and the probability of exclusion in duos and trios were high for the populations in this study.
authors.affiliation: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark(1).
authors.forename: L
authors.initials: L
authors.lastname: Poulsen
authors.affiliation: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark(1).
authors.forename: C
authors.initials: C
authors.lastname: Tomas
authors.affiliation: National Forensic Laboratory, Police, Ministry of the Interior, Vodovodna 95, 1000 Ljubljana, Slovenia.
authors.forename: K
authors.initials: K
authors.lastname: Drobnič
authors.affiliation: The State Forensic Medicine Service under the Ministry of Justice of the Republic of Lithuania, Vilnius, Lithuania.
authors.forename: V
authors.initials: V
authors.lastname: Ivanova
authors.affiliation: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark(1).
authors.forename: H S
authors.initials: HS
authors.lastname: Mogensen
authors.affiliation: Scientific Support Section, Subdivision of Biological and Biochemical Examinations and Analyses F.S.D.-Hellenic Police, Athens, Greece.
authors.forename: A
authors.initials: A
authors.lastname: Kondili
authors.affiliation: Scientific Support Section, Subdivision of Biological and Biochemical Examinations and Analyses F.S.D.-Hellenic Police, Athens, Greece.
authors.forename: P
authors.initials: P
authors.lastname: Miniati
authors.affiliation: The State Forensic Medicine Service under the Ministry of Justice of the Republic of Lithuania, Vilnius, Lithuania.
authors.forename: D
authors.initials: D
authors.lastname: Bunokiene
authors.affiliation: The State Forensic Medicine Service under the Ministry of Justice of the Republic of Lithuania, Vilnius, Lithuania.
authors.forename: J
authors.initials: J
authors.lastname: Jankauskiene
authors.affiliation: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark(1). Electronic address: vania.pereira@sund.ku.dk.
authors.forename: V
authors.initials: V
authors.lastname: Pereira
authors.affiliation: Section of Forensic Genetics, Department of Forensic Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Frederik V's Vej 11, DK-2100 Copenhagen, Denmark(1).
authors.forename: N
authors.initials: N
authors.lastname: Morling
mesh_terms: D000415:Albania; D041321:Chromosomes, Human, X; D005260:Female; D053803:Forensic Genetics / Q000379:methods*; D005787:Gene Frequency; D008040:Genetic Linkage; D005819:Genetic Markers / Q000235:genetics; D014644:Genetic Variation; D005828:Genetics, Population / Q000379:methods*; D006239:Haplotypes; D006801:Humans; D007493:Iraq; D015810:Linkage Disequilibrium; D008097:Lithuania; D008297:Male; D018895:Microsatellite Repeats; D016133:Polymerase Chain Reaction / Q000379:methods; D017524:Slovenia; D014421:Turkey
chemical_list: D005819:Genetic Markers
keywords: Argus X-12; Forensic genetics; NGM SElect™; Population genetics