title: Mooren's ulcer: 30 years of follow-up.
abstract: METHODS
  A 33-year-old Caucasian female presented with epiphora, ocular pain, and foreign body sensation in both eyes for one month. Examination revealed bilateral peripheral corneal ulcers. The patient had been treated with immunomodulators, and she was treated in the left eye with peripheral semi-circular keratoplasty, penetrating keratoplasty, conjunctival-corneal-scleroplasty, buccal mucosal graft, tibial osteo-keratoprosthesis and finally, retinal detachment.
  
  
  CONCLUSIONS
  Mooren's ulcer is an immunological corneal disease. This lesion must be treated initially with immunomodulators. Surgical treatment should be considered when a risk of corneal perforation is present, when the perforation appears, or under acute necrosis.
authors.affiliation: Centro de Oftalmología Barraquer, Institut Universitari Barraquer, Barcelona, España. Electronic address: ferranvilaplanamira@gmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Vilaplana
authors.affiliation: Centro de Oftalmología Barraquer, Institut Universitari Barraquer, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Temprano
authors.affiliation: Centro de Oftalmología Barraquer, Institut Universitari Barraquer, Barcelona, España.
authors.forename: J L
authors.initials: JL
authors.lastname: Riquelme
authors.affiliation: Centro de Oftalmología Barraquer, Institut Universitari Barraquer, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Nadal
authors.affiliation: Centro de Oftalmología Barraquer, Institut Universitari Barraquer, Barcelona, España.
authors.forename: J
authors.initials: J
authors.lastname: Barraquer
mesh_terms: D000328:Adult; D002387:Cataract Extraction; D003131:Combined Modality Therapy; D003261:Contact Lenses; D016039:Corneal Transplantation / Q000379:methods*; D003320:Corneal Ulcer / Q000188:drug therapy / Q000276:immunology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D015948:Keratoplasty, Penetrating; D009061:Mouth Mucosa / Q000637:transplantation; D012086:Reoperation; D013977:Tibia / Q000637:transplantation; D016042:Transplantation, Heterotopic; D014821:Vitrectomy
chemical_list: D007166:Immunosuppressive Agents
keywords: Corneal perforation; Desprendimiento de retina; Immunosuppression; Inmunosupresión; Keratoplasty; Mooren's ulcer; Osteo-keratoprosthesis; Osteo-queratoprótesis; Perforación corneal; Queratoplastia; Retinal detachment; Vitrectomy; Vitrectomía; Úlcera de Mooren