title: Disease progression in aggressive periodontitis patients. A Retrospective Study.
abstract: The primary aim of this study was to retrospectively ascertain disease progression in a cohort of aggressive periodontitis patients (AgP).
  
  
  
  Patients treated at a specialist setting and referred back to general practice for periodontal maintenance were recalled and examined in a single visit. Disease progression during follow-up was assessed and historical data collected from the patient's records. Factors that could potentially influence tooth loss rates at the patient level were explored by linear regression analysis. At the tooth level, chi-square test and OR for tooth loss were calculated.
  
  
  
  Sixty-six subjects completed the study. The mean follow-up was 6.97 years (95% CI 6.25-7.69). The mean annual tooth loss rate was 0.27 teeth per patient/year (95% CI 0.17-0.36). At the patient level, having received surgical treatment and the performance of interproximal cleaning were found to significantly reduce the annual tooth loss rates. At the tooth level, deep probing depths after treatment were significantly associated with increased tooth loss rates (OR 4.39 for PPD 5-6 mm and OR 11.68 for PPD >6 mm, respectively, compared with PPD <5 mm).
  
  
  
  In this sample of patients, the annual tooth loss rates were found to be higher than previously described.
authors.affiliation: Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, UK.|Periodontology Unit, Universidad de Santiago de Compostela, Santiago de Compostela, Spain.
authors.forename: José
authors.initials: J
authors.lastname: Dopico
authors.affiliation: Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, UK.|Clinical Oral Research Centre, Institute of Dentistry, Queen Mary University London (QMUL), London, UK.
authors.forename: Luigi
authors.initials: L
authors.lastname: Nibali
authors.affiliation: Periodontology Unit, Division of Clinical Research, UCL Eastman Dental Institute, London, UK.|Clinical Oral Research Centre, Institute of Dentistry, Queen Mary University London (QMUL), London, UK.
authors.forename: Nikos
authors.initials: N
authors.lastname: Donos
mesh_terms: D010520:Aggressive Periodontitis; D016301:Alveolar Bone Loss; D018450:Disease Progression; D005500:Follow-Up Studies; D006801:Humans; D017622:Periodontal Attachment Loss; D010514:Periodontal Pocket; D012189:Retrospective Studies; D016388:Tooth Loss; D016896:Treatment Outcome
keywords: periodontal disease; periodontitis