title: Cerebellar ataxia as presenting feature of hypothyroidism.
abstract: Symptoms and signs of the hypothyroidism vary in relation to the magnitude and acuteness of the thyroid hormone deficiency. The usual clinical features are constipation, fatigue, cold intolerance and weight gain. Rarely it can present with neurologic problems like reversible cerebellar ataxia, dementia, peripheral neuropathy, psychosis and coma. Hypothyroidism should be suspected in all cases of ataxia, as it is easily treatable. A 40 year-old male presented with the history facial puffiness, hoarseness of voice and gait-ataxia. Investigations revealed frank primary hypothyroidism. Anti-TPO antibody was positive. Thyroxine was started and patient improved completely within eight weeks. Hypothyroidism can present with ataxia as presenting feature. Hypothyroidism should be considered in all cases of cerebellar ataxia as it is a reversible cause of ataxia.
authors.affiliation: Department of Medicine, Government Medical College, Jammu, India.
authors.forename: Suman Kumar
authors.initials: SK
authors.lastname: Kotwal
authors.affiliation: Department of Pathology, Government Medical College, Jammu, India.
authors.forename: Shalija
authors.initials: S
authors.lastname: Kotwal
authors.affiliation: Department of Medicine, Government Medical College, Jammu, India.
authors.forename: Rohan
authors.initials: R
authors.lastname: Gupta
authors.affiliation: Department of Medicine, Government Medical College, Jammu, India.
authors.forename: Jang Bhadur
authors.initials: JB
authors.lastname: Singh
authors.affiliation: Department of Medicine, Government Medical College, Jammu, India.
authors.forename: Annil
authors.initials: A
authors.lastname: Mahajan
mesh_terms: D000328:Adult; D002524:Cerebellar Ataxia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D020234:Gait Ataxia / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D007037:Hypothyroidism / Q000150:complications* / Q000503:physiopathology; D008279:Magnetic Resonance Imaging; D008297:Male