title: Lack of Utility of Nasopharyngeal Swabs for Diagnosis of Burkholderia pseudomallei Pneumonia in Paediatric Patients.
abstract: Diagnosis of Burkholderia pseudomallei pneumonia in children is challenging. We investigated the utility of nasopharyngeal swabs taken from 194 paediatric patients on admission with radiologically proven pneumonia. Melioidosis was proven in 0.5% of samples tested and only in a third of those known to be bacteraemic with B. pseudomallei. It appears unlikely that culture of nasopharyngeal secretions is helpful to confirm B. pseudomallei pneumonia in paediatric patients.
authors.affiliation: Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia pascohearn@hotmail.com.
authors.forename: Pasco
authors.initials: P
authors.lastname: Hearn
authors.affiliation: Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Angkor Hospital for Children, Siem Reap, Cambodia.
authors.forename: Claudia
authors.initials: C
authors.lastname: Turner
authors.affiliation: Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia.
authors.forename: Kuong
authors.initials: K
authors.lastname: Suy
authors.affiliation: Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Angkor Hospital for Children, Siem Reap, Cambodia.
authors.forename: Sona
authors.initials: S
authors.lastname: Soeng
authors.affiliation: Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
authors.forename: Nicholas P J
authors.initials: NP
authors.lastname: Day
authors.affiliation: Cambodia-Oxford Medical Research Unit, Angkor Hospital for Child, Siem Reap, Cambodia Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK.
authors.forename: Paul
authors.initials: P
authors.lastname: Turner
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016957:Burkholderia pseudomallei / Q000302:isolation & purification*; D002160:Cambodia; D006801:Humans; D008554:Melioidosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D018410:Pneumonia, Bacterial / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology; D013902:Radiography, Thoracic
chemical_list: D000900:Anti-Bacterial Agents
keywords: Burkholderia pseudomallei; melioidosis; nasopharyngeal swab; paediatric