title: Aluminum-induced pneumoconiosis confirmed by analytical scanning electron microscopy: A case report and review of the literature.
abstract: Aluminum-induced lung injury is an uncommon, yet recognized pneumoconiosis capable of causing severe interstitial fibrosis. Important attention to the clinical history including occupational exposure is an essential component to making the correct diagnosis, despite which careful examination of the lung specimen is necessary to exclude other more common disease entities. We present a case of aluminum-induced pneumoconiosis in the setting of a bilateral lung transplant patient. Additionally, we review the literature on aluminum-induced pneumoconiosis and demonstrate the use of ancillary techniques including backscattered electron imaging and energy-dispersive spectrometry to aid in diagnosis.
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: John
authors.initials: J
authors.lastname: Carney
authors.affiliation: b Department of Radiology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Page
authors.initials: P
authors.lastname: McAdams
authors.affiliation: c Department of Internal Medicine, Division of Pulmonary and Occupational Medicine , University of South Florida , Tampa , FL , USA.
authors.forename: James
authors.initials: J
authors.lastname: McCluskey
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Victor L
authors.initials: VL
authors.lastname: Roggli
mesh_terms: D000535:Aluminum / Q000009:adverse effects*; D004391:Dust; D006801:Humans; D016040:Lung Transplantation; D008297:Male; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D011009:Pneumoconiosis / Q000175:diagnosis* / Q000209:etiology*; D013052:Spectrometry, X-Ray Emission
chemical_list: D004391:Dust; D000535:Aluminum
keywords: Aluminum-induced pneumoconiosis; scanning electron microscopy