title: Copper-induced ammonia N-H functionalization.
abstract: The activation of ammonia has been achieved with the aid of the Tp(Ms)Cu core (Tp(Ms) = hydrotris(3-mesityl-pyrazolyl)borate). Complexes of the general composition Tp(Ms)Cu(amine) (1-4) including the ammonia adduct Tp(Ms)Cu(NH3) (1) have been synthesized and fully spectroscopical- and structurally characterized. Coordinated ammonia in 1 has been reacted with Ph3CPF6 yielding Tp(Ms)Cu(NH2CPh3) (5) as a result of N-H cleavage and N-C bond formation. In a parallel manner the catalytic functionalization of ammonia with ethyl diazoacetate leading to glycinate derivatives has been developed with Tp(Ms)Cu(THF) as the catalyst, in the first example of this transformation with ammonia and a copper-based system.
authors.affiliation: Laboratorio de Catálisis Homogénea, Unidad Asociada al CSIC, CIQSO-Centro de Investigación en Química Sostenible and Departamento de Química, Universidad de Huelva, Campus de El Carmen, 21007 Huelva, Spain. perez@dqcm.uhu.es.
authors.forename: María
authors.initials: M
authors.lastname: Álvarez
authors.forename: Eleuterio
authors.initials: E
authors.lastname: Álvarez
authors.forename: Manuel R
authors.initials: MR
authors.lastname: Fructos
authors.forename: Juan
authors.initials: J
authors.lastname: Urbano
authors.forename: Pedro J
authors.initials: PJ
authors.lastname: Pérez