title: Time to abandon three-phase trials?
authors.affiliation: University of Adelaide, Adelaide, SA 5005, Australia andrew.metcalfe@adelaide.edu.au.
authors.forename: Andrew V
authors.initials: AV
authors.lastname: Metcalfe
mesh_terms: D017321:Clinical Trials, Phase I as Topic; D064420:Drug-Related Side Effects and Adverse Reactions; D064368:Healthy Volunteers; D006801:Humans; D018570:Risk Assessment