title: Diagnostic value of strain elastography for differentiation between renal cell carcinoma and transitional cell carcinoma of kidney.
abstract: The objective of our study was to prospectively evaluate the diagnostic performance of strain elastography for differentiation between renal cell carcinomas (RCCs) and transitional cell carcinomas (TCCs) of kidney.
  
  
  
  A total of 99 consecutive patients who were referred to our hospital because of a newly diagnosed solid renal mass suspicious for malignancy on radiological screenings were evaluated with sonography, including strain elastography. Strain elastography was used to compare the stiffness of the renal masses and renal cortex. The ratio of strain in a renal mass and nearby renal cortex was defined as the strain index value. Mean strain index values for RCCs and TCCs were compared, and mean strain index values between histological subtypes of RCC were also compared.
  
  
  
  Although TCCs were smaller than RCCs (p < 0.001), there were no significant differences in gender distribution and mean age of the patients, and mean probe-tumor distance between RCC and TCC. The mean strain index value ±SD for TCC (5.18 ± 1.12) was significantly higher than the value for RCC (4.04 ± 0.72; p < 0.001). Mean strain index value for papillary cell carcinomas (4.09 ± 0.45) was slightly higher than that for clear cell carcinomas (3.85 ± 0.78): however, the difference was not statistically significant (p = 0.51).
  
  
  
  Strain elastography can be used as a valuable imaging technique for preoperative differentiation between RCC and TCC of kidney.
authors.affiliation: Department of Radiology, Izmir Katip Çelebi University, School of Medicine, Izmir, Turkey. drfatihinci@gmail.com.|Department of Radiology, Atatürk Training and Research Hospital, Izmir Katip Celebi University, Polat Caddesi, Karabaglar, Izmir, 35160, Turkey. drfatihinci@gmail.com.
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Inci
authors.affiliation: Department of Radiology, Atatürk Training and Research Hospital, Izmir Katip Celebi University, Polat Caddesi, Karabaglar, Izmir, 35160, Turkey.
authors.forename: Tugce Ozlem
authors.initials: TO
authors.lastname: Kalayci
authors.affiliation: Department of Radiology, Kırıkkale University, School of Medicine, Kırıkkale, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Tan
authors.affiliation: Department of Radiology, Atatürk Training and Research Hospital, Izmir Katip Celebi University, Polat Caddesi, Karabaglar, Izmir, 35160, Turkey.
authors.forename: Sebnem
authors.initials: S
authors.lastname: Karasu
authors.affiliation: Department of Radiology, Gaziosmanpasa University, School of Medicine, Tokat, Turkey.
authors.forename: Eda
authors.initials: E
authors.lastname: Albayrak
authors.affiliation: Department of Radiology, Izmir Katip Çelebi University, School of Medicine, Izmir, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Cakir
authors.affiliation: Department of Pathology, Izmir Katip Çelebi University, School of Medicine, Izmir, Turkey.
authors.forename: Irfan
authors.initials: I
authors.lastname: Ocal
authors.affiliation: Department of Radiology, Okmeydanı Education and Research Hospital, Istanbul, Turkey.
authors.forename: Fuat
authors.initials: F
authors.lastname: Ozkan
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D054459:Elasticity Imaging Techniques; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012680:Sensitivity and Specificity
keywords: Renal cell carcinoma; Strain elastography; Strain index value; Transitional cell carcinoma