title: Intensity-modulated radiation therapy dose verification using fluence and portal imaging device.
abstract: Patient-specific quality assurance for intensity-modulated radiation therapy (IMRT) dose verification is essential. The aim of this study is to provide a new method based on the relative error distribution by comparing the fluence map from the treatment planning system (TPS) and the incident fluence deconvolved from the electronic portal imaging device (EPID) images. This method is validated for 10 head and neck IMRT cases. The fluence map of each beam was exported from the TPS and EPID images of the treatment beams were acquired. Measured EPID images were deconvolved to the incident fluence with proper corrections. The relative error distribution between the TPS fluence map and the incident fluence from the EPID was created. This was also created for a 2D diode array detector. The absolute point dose was measured with an ionization chamber, and the dose distribution was measured by a radiochromic film. In three cases, MLC leaf positions were intentionally changed to create the dose error as much as 5% against the planned dose and our fluence-based method was tested using gamma index. Absolute errors between the predicted dose of 2D diode detector and of our method and measurements were 1.26% ± 0.65% and 0.78% ± 0.81% respectively. The gamma passing rate (3% global / 3 mm) of the TPS was higher than that of the 2D diode detector (p< 0.02), and lower than that of the EPID (p < 0.04). The gamma passing rate (2% global / 2 mm) of the TPS was higher than that of the 2D diode detector, while the gamma passing rate of the TPS was lower than that of EPID (p < 0.02). For three modified plans, the predicted dose errors against the measured dose were 1.10%, 2.14%, and -0.87%. The predicted dose distributions from the EPID were well matched to the measurements. Our fluence-based method provides very accurate dosimetry for IMRT patients. The method is simple and can be adapted to any clinic for complex cases.
authors.affiliation: Osaka University Graduate School of Medicine. sumida@radonc.med.osaka-u.ac.jp.
authors.forename: Iori
authors.initials: I
authors.lastname: Sumida
authors.forename: Hajime
authors.initials: H
authors.lastname: Yamaguchi
authors.forename: Indra J
authors.initials: IJ
authors.lastname: Das
authors.forename: Hisao
authors.initials: H
authors.lastname: Kizaki
authors.forename: Keiko
authors.initials: K
authors.lastname: Aboshi
authors.forename: Mari
authors.initials: M
authors.lastname: Tsujii
authors.forename: Yuji
authors.initials: Y
authors.lastname: Yamada
authors.forename: Osamu
authors.initials: O
authors.lastname: Suzuki
authors.forename: Yuji
authors.initials: Y
authors.lastname: Seo
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Isohashi
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Ogawa
mesh_terms: D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000295:instrumentation*; D009369:Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D010315:Particle Accelerators / Q000295:instrumentation*; D019047:Phantoms, Imaging; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*