title: Papillary thyroid carcinoma and subclinical thyrotoxicosis: Brief insight into the thyroid regulators other than thyroid stimulating hormone.
abstract: Papillary thyroid carcinoma (PTC) is the most common thyroid malignancy. It usually develops in euthyroid patients with history of long standing Hashimoto's thyroiditis. Here, we describe the development of PTC in a seronegative patient with subclinical thyrotoxicosis. We suggest that any cold nodule having high-risk features on ultrasonography in hyperthyroid patients should be thoroughly evaluated for the possibility of a thyroid malignancy and the possible role of nonthyroid stimulating hormone regulatory molecules, in thyroid carcinogenesis needs to be further explored.
authors.forename: Somanath
authors.initials: S
authors.lastname: Padhi
authors.affiliation: Department of Endocrinology and Metabolism, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
authors.forename: Jaya Prakash
authors.initials: JP
authors.lastname: Sahoo
authors.forename: Sadishkumar
authors.initials: S
authors.lastname: Kamalanathan
authors.forename: RajLaxmi
authors.initials: R
authors.lastname: Sarangi
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D002291:Carcinoma, Papillary / Q000150:complications* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis; D013964:Thyroid Neoplasms / Q000150:complications* / Q000473:pathology; D013971:Thyrotoxicosis / Q000209:etiology* / Q000378:metabolism* / Q000473:pathology; D013972:Thyrotropin / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D013972:Thyrotropin