title: Vitrified/warmed single blastocyst transfer in preimplantation genetic diagnosis/preimplantation genetic screening cycles.
abstract: OBJECTIVE
  To investigate the single blastocyst transfer in preimplantation genetic diagnosis (PGD)/preimplantation genetic screening (PGS) cycles.
  
  
  METHODS
  80 PGD/PGS cycles undergoing blastocyst biopsy were studied. There were 88 warming cycles during the study period. Only one warmed blastocyst was transferred per cycle. The outcomes were followed up to the infants were born.
  
  
  RESULTS
  The embryo implantation rate was 54.55% (48/88). The clinical pregnancy rate was 54.55% (48/88) per transfer cycle and 60% (48/80) per initial PGD/PGS cycle. There was no multi-pregnant in this study. The live birth rate was 42.05% (37/88) per transfer cycle and 46.25% (37/80) per initial PGD/PGS cycle.
  
  
  CONCLUSIONS
  In PGD/PGS cycles, single blastocyst transfer reduces the multiple pregnancy rate without affecting the clinical outcomes.
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third HospitalBeijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education and Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive TechnologyBeijing 100191, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Huang
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third HospitalBeijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education and Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive TechnologyBeijing 100191, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Li
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third HospitalBeijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education and Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive TechnologyBeijing 100191, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Lian
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third Hospital Beijing 100191, China.
authors.forename: Lixue
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third Hospital Beijing 100191, China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Shi
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third HospitalBeijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education and Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive TechnologyBeijing 100191, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Qiao
authors.affiliation: Department of Obstetrics and Gynecology, Reproductive Medical Centre, Peking University Third HospitalBeijing 100191, China; Key Laboratory of Assisted Reproduction, Ministry of Education and Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive TechnologyBeijing 100191, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Liu
keywords: Preimplantation genetic diagnosis/preimplantation genetic screening; multiple births; single blastocyst transfer; vitrification