title: Sequence type 72 community-associated meticillin-resistant Staphylococcus aureus emerged as a predominant clone of nasal colonization in newly admitted patients.
abstract: Current knowledge of community-associated (CA) meticillin-resistant Staphylococcus aureus (MRSA) carriage in hospitalized patients is incomplete. Genotypic characteristics of 637 nasal MRSA isolates from newly admitted patients in South Korea were investigated. Sequence type (ST) 72 accounted for 52.1%, 46.3%, and 52.8% of the isolates during the periods of 2007-2008, 2009-2010, and 2013-2014, respectively. Instead of classic MRSA clones responsible for healthcare-associated infections, including ST5 and ST239, MRSA with community genotype ST72 was the predominant strain in newly admitted patients regardless of age and home province of the patients. Active strategies are needed to prevent healthcare-associated infection by CA-MRSA.
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: S Y
authors.initials: SY
authors.lastname: Park
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Asia Pacific Foundation for Infectious Diseases (APFID), Seoul, South Korea; Infection Control Office, Samsung Medical Center, Seoul, South Korea. Electronic address: iddrchung@gmail.com.
authors.forename: D R
authors.initials: DR
authors.lastname: Chung
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: J R
authors.initials: JR
authors.lastname: Yoo
authors.affiliation: Asia Pacific Foundation for Infectious Diseases (APFID), Seoul, South Korea.
authors.forename: J Y
authors.initials: JY
authors.lastname: Baek
authors.affiliation: Asia Pacific Foundation for Infectious Diseases (APFID), Seoul, South Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: Y E
authors.initials: YE
authors.lastname: Ha
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: C-I
authors.initials: CI
authors.lastname: Kang
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: K R
authors.initials: KR
authors.lastname: Peck
authors.affiliation: Department of Laboratory Medicine and Genetics, Samsung Medical Center, Seoul, South Korea.
authors.forename: N Y
authors.initials: NY
authors.lastname: Lee
authors.affiliation: Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea; Asia Pacific Foundation for Infectious Diseases (APFID), Seoul, South Korea.
authors.forename: J-H
authors.initials: JH
authors.lastname: Song
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology / Q000382:microbiology*; D002648:Child; D002675:Child, Preschool; D002999:Clone Cells; D017714:Community-Acquired Infections / Q000453:epidemiology / Q000382:microbiology*; D003955:Diagnostic Tests, Routine; D005260:Female; D005838:Genotype; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D055624:Methicillin-Resistant Staphylococcus aureus / Q000145:classification* / Q000302:isolation & purification; D008875:Middle Aged; D017720:Molecular Epidemiology; D058885:Multilocus Sequence Typing; D009297:Nasal Mucosa / Q000382:microbiology; D056910:Republic of Korea / Q000453:epidemiology; D013203:Staphylococcal Infections / Q000453:epidemiology / Q000382:microbiology*; D055815:Young Adult
keywords: Genotype; Meticillin-resistant Staphylococcus aureus; Nasal colonization