title: AGTR1 has undergone natural selection in Euro-Asian populations in relation to ambient temperature that predisposes Chinese populations to essential hypertension.
authors.affiliation: Department of Biochemistry, School of Medicine, Ningbo University, Ningbo, China; State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.
authors.forename: Lin-Dan
authors.initials: LD
authors.lastname: Ji
authors.affiliation: Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China; Laboratory for Genetics of Disease Susceptibility, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Nelson L S
authors.initials: NL
authors.lastname: Tang
authors.affiliation: State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China; Department of Preventive Medicine, School of Medicine, Ningbo University, Ningbo, China. Electronic address: xujin1@nbu.edu.cn.
authors.forename: Jin
authors.initials: J
authors.lastname: Xu
mesh_terms: D044466:Asian People / Q000235:genetics*; D000075222:Essential Hypertension; D006801:Humans; D006973:Hypertension / Q000175:diagnosis / Q000235:genetics*; D020641:Polymorphism, Single Nucleotide / Q000235:genetics; D044140:Receptor, Angiotensin, Type 1 / Q000235:genetics*; D012641:Selection, Genetic / Q000235:genetics*; D013696:Temperature; D044465:White People / Q000235:genetics*
chemical_list: C544065:AGTR1 protein, human; D044140:Receptor, Angiotensin, Type 1
keywords: AGTR1; Ambient temperature; Genetic susceptibility; Hypertension; Natural selection; Renin–angiotensin–aldosterone system