title: Immunometabolism: Metabolism fine-tunes macrophage activation.
abstract: A signaling pathway that rewires metabolism in macrophages to trigger changes in gene expression has been identified.
authors.affiliation: Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States.
authors.forename: AnnMarie
authors.identifier: 0000-0001-6104-0477
authors.initials: A
authors.lastname: Torres
authors.affiliation: Department of Nutrition, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, Chapel Hill, United States.
authors.forename: Liza
authors.identifier: 0000-0002-5337-8037
authors.initials: L
authors.lastname: Makowski
authors.affiliation: Department of Cancer Biology, University of Pennsylvania Perelman School of Medicine, Philadelphia, United States.
authors.forename: Kathryn E
authors.identifier: 0000-0002-2281-0042
authors.initials: KE
authors.lastname: Wellen
mesh_terms: D015870:Gene Expression; D006801:Humans; D008262:Macrophage Activation; D008264:Macrophages / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D051057:Proto-Oncogene Proteins c-akt
keywords: akt, acly; cell biology; immunology; immunometabolism; mTORC1; macrophage activation; macrophage metabolism; mouse