title: Presurgical Evaluation of Pancreatic Cancer: A Comprehensive Imaging Comparison of CT Versus MRI.
abstract: OBJECTIVE
  The purpose of this study was to compare comprehensive CT and MRI in the presurgical evaluation of pancreatic cancer.
  
  
  METHODS
  Thirty-eight patients with pathologically proven pancreatic cancer were included in a retrospective study. CT with negative-contrast CT cholangiopancreatography and CT angiography (CTA) (CT image set) versus MRI with MRCP and MR angiography (MRI image set) were analyzed independently by two reviewers for tumor detection, extension, metastasis, vascular invasion, and resectability. These results were compared with the surgical and pathologic findings.
  
  
  RESULTS
  The rate of detection of tumors was higher with MRI than with CT but not significantly so (reviewer 1, p = 1.000; reviewer 2, p = 0.500). In the evaluation of vessel involvement, nodal status, and resectability, although CT had higher ROC AUC values than did MRI (reviewer 1, 0.913 vs 0.858, 0.613 vs 0.503, and 0.866 vs 0.774; reviewer 2, 0.879 vs 0.849, 0.640 vs 0.583, and 0.830 vs 0.815), the differences were not statistically significant (p = 0.189 vs 0.494, 0.328 vs 0.244, and 0.193 vs 0.813 for reviewers 1 and 2). In the evaluation of tumor extension and organ metastases in the 38 patients, correct diagnosis of one of two liver metastases was achieved with both image sets, one case of omental and one case of peritoneal seeding were underestimated, and one case of stomach invasion was overestimated.
  
  
  CONCLUSIONS
  MRI and CT had similar performance in the presurgical evaluation of pancreatic cancer.
authors.affiliation: 1 All authors: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Rd, Jiangsu 214002, PR China.
authors.forename: Fang-Ming
authors.initials: FM
authors.lastname: Chen
authors.affiliation: 1 All authors: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Rd, Jiangsu 214002, PR China.
authors.forename: Jian-Ming
authors.initials: JM
authors.lastname: Ni
authors.affiliation: 1 All authors: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Rd, Jiangsu 214002, PR China.
authors.forename: Zhui-Yang
authors.initials: ZY
authors.lastname: Zhang
authors.affiliation: 1 All authors: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Rd, Jiangsu 214002, PR China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.affiliation: 1 All authors: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Rd, Jiangsu 214002, PR China.
authors.forename: Bin
authors.initials: B
authors.lastname: Li
authors.affiliation: 1 All authors: Department of Radiology, Wuxi Second People's Hospital Affiliated to Nanjing Medical University, 68 Zhongshan Rd, Jiangsu 214002, PR China.
authors.forename: Chun-Juan
authors.initials: CJ
authors.lastname: Jiang
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011300:Preoperative Care; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: CT; MRI; pancreatic cancer; presurgical evaluation