title: Better plans and more powerful evidence are needed in the research and treatment of chronic hepatitis B in China.
abstract: China has the first largest global pool of chronic hepatitis B (CHB) infection. With the implementation of comprehensive intervention of neonatal vaccination based on national strategy, some achievements have been made in control of hepatitis B in China. However, some problems remain unresolved in the research field as well as management of CHB. Currently, empirical therapy, poor study design, inefficient management, low compliance rate of patients, lack of public awareness and economic factor hampers the research and treatment of CHB in China. We propose that China should take more effective measures to improve the study quality, social management, the relief of economic burden for the needed patients, public awareness, evidence-based policies and medicine, supervision for clinical practice, diagnostics ability and laboratory quality, the compliance of patients, and the quality of Traditional Chinese Medicine (TCM) in the management of CHB infection in the future.
authors.affiliation: Department of Transfusion Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233, China.
authors.forename: Changtai
authors.initials: C
authors.lastname: Zhu
authors.affiliation: Department of Laboratory Medicine, Kunshan Hospital Affiliated to Nanjing University of Traditional Chinese Medicine Kunshan 215300, Jiangsu Province, China.
authors.forename: Yulu
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Infectious Diseases, Shanghai Jiao Tong University Affiliated Sixth People's Hospital Shanghai 200233, China.
authors.forename: Lihui
authors.initials: L
authors.lastname: Jiang
authors.affiliation: Department of Internal Medicine, Singapore General Hospital 160146, Singapore.
authors.forename: Baoqiong
authors.initials: B
authors.lastname: Ding
authors.affiliation: Department of Traditional Chinese Medicine, Shanghai Jiao Tong University Affiliated Sixth People's Hospital No. 600 Yishan Road, Shanghai 200233, China.
authors.forename: Yongning
authors.initials: Y
authors.lastname: Sun
keywords: China; Chronic hepatitis B; management; traditional Chinese medicine; treatment