title: A New Way to Diversify Antibodies by DNA Transposition.
abstract: While searching for new therapeutics against malaria, Lanzavecchia and colleagues discovered that antibodies can be diversified by DNA sequences encoded outside of antibody genes.
authors.affiliation: Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA. Electronic address: drobbiani@rockefeller.edu.
authors.forename: Davide F
authors.initials: DF
authors.lastname: Robbiani
authors.affiliation: Laboratory of Molecular Immunology, The Rockefeller University, New York, New York 10065, USA; Howard Hughes Medical Institute, The Rockefeller University, New York, New York 10065, USA. Electronic address: nussen@rockefeller.edu.
authors.forename: Michel C
authors.initials: MC
authors.lastname: Nussenzweig
mesh_terms: D000911:Antibodies, Monoclonal / Q000276:immunology*; D000918:Antibody Specificity; D000940:Antigenic Variation / Q000276:immunology*; D000953:Antigens, Protozoan / Q000276:immunology*; D006801:Humans; D008288:Malaria / Q000276:immunology*; D016254:Mutagenesis, Insertional / Q000235:genetics*; D010963:Plasmodium falciparum / Q000276:immunology*; D011971:Receptors, Immunologic / Q000276:immunology*
chemical_list: D000911:Antibodies, Monoclonal; D000953:Antigens, Protozoan; D011971:Receptors, Immunologic