title: Human uterus transplantation in focus.
abstract: BACKGROUND
  Uterus transplantation (UTx) is introduced as the first treatment for absolute uterine factor infertility (AUFI), affecting 1:500 fertile aged women. This review presents potential patients, research and human UTx cases.
  
  
  METHODS
  Published articles and our research experience.
  
  
  RESULTS
  The first UTx live births in 2014 established UTx as a possible treatment for AUFI. This was proceeded by 15 years of systematic research.
  
  
  RESULTS
  Is a deceased donor UTx as effective as the proven successful live donor UTx?.
  
  
  CONCLUSIONS
  Human UTx trials will accumulate data on risks, effectiveness and long-term consequences for donors, recipients and children. These should also include aspects of quality of life, psychological well-being and cognitive/neuropsychiatric development of children.
  
  
  CONCLUSIONS
  All new activities in human UTx within the coming years should be conducted as prospective observational studies, and data should also be collected within an international registry.
authors.affiliation: Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, 41345 Gothenburg, Sweden.
authors.forename: Pernilla
authors.initials: P
authors.lastname: Dahm-Kähler
authors.affiliation: Department of Obstetrics and Gynecology, La Fe University Hospital, University of Valencia, 46026 Valencia, Spain.
authors.forename: Cesar
authors.initials: C
authors.lastname: Diaz-Garcia
authors.affiliation: Department of Obstetrics and Gynecology, Sahlgrenska Academy, University of Gothenburg, 41345 Gothenburg, Sweden Stockholm IVF, 12063 Stockholm, Sweden mats.brannstrom@obgyn.gu.se.
authors.forename: Mats
authors.initials: M
authors.lastname: Brännström
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D004992:Ethics, Medical; D005260:Female; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000601:surgery*; D019520:Living Donors; D014599:Uterus / Q000002:abnormalities / Q000637:transplantation*
keywords: infertility; transplantation; uterus