title: Comparative Analysis of the Proliferative Potential of Human Mesenchymal Stromal Cells from Extraembryonic Organs, Endometrium, and Adipose Tissue.
abstract: Proliferative activity of mesenchymal stromal cells isolated from five sources (chorionic villi, Wharton's jelly, amnion, endometrium, and adipose tissue) was compared by flow cytometry and real-time PCR (by the content of mRNA of genes encoding of cell cycle regulators). Mesenchymal stromal cells derived from the endometrium demonstrated maximum stability and high proliferative potential.
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia. irina.genet@gmail.com.
authors.forename: I A
authors.initials: IA
authors.lastname: Fedorova
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: Y V
authors.initials: YV
authors.lastname: Rudimova
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: M N
authors.initials: MN
authors.lastname: Yushina
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: V D
authors.initials: VD
authors.lastname: Chuprynin
authors.affiliation: V. I. Kulakov Research Center of Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: A M
authors.initials: AM
authors.lastname: Savilova
mesh_terms: D000273:Adipose Tissue / Q000166:cytology*; D000328:Adult; D000650:Amnion / Q000166:cytology*; D002454:Cell Differentiation; D049109:Cell Proliferation; D002478:Cells, Cultured; D002824:Chorionic Villi / Q000254:growth & development*; D004717:Endometrium / Q000166:cytology*; D005260:Female; D005434:Flow Cytometry; D006801:Humans; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D060888:Real-Time Polymerase Chain Reaction; D059631:Wharton Jelly / Q000166:cytology*; D055815:Young Adult
keywords: apoptosis; multipotent mesenchymal stromal cells; proliferation; umbilical cord