title: Women and functional dyspepsia.
abstract: Functional dyspepsia is relatively common yet poorly understood. The best accepted diagnostic criteria are the Rome III criteria. The epidemiology, healthcare seeking rates, impact and pathophysiology are reviewed with a focus on women. Treatment is limited with no clearly established regimen currently recommended. Duodenal eosinophilia may be found in a subset. Proton pump inhibitors and prokinetic agents represent the standard therapeutic regimen after Helicobacter pylori infection has been eliminated. Some novel agents such as the prokinetic acotiamide appear promising; however, the need for a safe and efficacious treatment remains largely unmet. This review also describes the currently available management options for functional dyspepsia.
authors.affiliation: Faculty of Health & Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia.
authors.forename: Kate
authors.initials: K
authors.lastname: Napthali
authors.affiliation: Faculty of Health & Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia.
authors.forename: Natasha
authors.initials: N
authors.lastname: Koloski
authors.affiliation: Faculty of Health & Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia.
authors.forename: Marjorie M
authors.initials: MM
authors.lastname: Walker
authors.affiliation: Faculty of Health & Medicine, University of Newcastle, Callaghan, NSW, 2308, Australia.
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Talley
mesh_terms: D004415:Dyspepsia / Q000175:diagnosis* / Q000188:drug therapy* / Q000453:epidemiology / Q000503:physiopathology*; D005260:Female; D005765:Gastrointestinal Agents / Q000627:therapeutic use*; D016481:Helicobacter Infections / Q000175:diagnosis* / Q000188:drug therapy*; D006801:Humans; D054328:Proton Pump Inhibitors / Q000627:therapeutic use*
chemical_list: D005765:Gastrointestinal Agents; D054328:Proton Pump Inhibitors
keywords: Helicobacter pylori; functional dyspepsia; prokinetics; proton pump inhibitors