title: Infusion-related risks associated with chemotherapy.
abstract: This article provides a comprehensive overview of the risks associated with the administration of chemotherapy, monoclonal antibodies and targeted or biological therapies in the management of solid tumours. The main physiological actions of these agents are discussed, with reference to the immediate infusion-related side effects and complications that may arise from an extravasation injury. The article focuses on the identification and early recognition of these risk factors to implement preventive measures and appropriate management strategies.
authors.affiliation: Clatterbridge Cancer Centre, Merseyside, England.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Gallimore
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D001691:Biological Therapy / Q000009:adverse effects*; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000517:prevention & control; D006801:Humans; D007262:Infusions, Intravenous / Q000009:adverse effects*; D009369:Neoplasms / Q000188:drug therapy; D012307:Risk Factors; D006113:United Kingdom
chemical_list: D000911:Antibodies, Monoclonal; D000970:Antineoplastic Agents
keywords: biological therapies; chemotherapy; extravasation; infusion reactions; monoclonal antibodies; oncology; side effects