title: Pancreas Transplantation in the Modern Era.
abstract: The field of pancreas transplantation has evolved from an experimental procedure in the 1980s to become a routine transplant in the modern era. With short- and long-term outcomes continuing to improve and the significant mortality, quality-of-life, and end-organ disease benefits, pancreas transplantation should be offered to more patients. In this article, we review current indications, patient selection, surgical considerations, complications, and outcomes in the modern era of pancreas transplantation.
authors.affiliation: Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Clinical Science Cntr-H4/772, Madison, WI 53792, USA. Electronic address: rrredfield@wisc.edu.
authors.forename: Robert R
authors.initials: RR
authors.lastname: Redfield
authors.affiliation: Division of Endocrinology, Diabetes & Metabolism, Department of Medicine, University of Pennsylvania Perelman School of Medicine, 2-134 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Rickels
authors.affiliation: Division of Transplantation, Department of Surgery, University of Pennsylvania Perelman School of Medicine, 3400 Spruce Street, Philadelphia, PA 19104-4283, USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Naji
authors.affiliation: Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, 600 Highland Avenue, Clinical Science Cntr-H4/772, Madison, WI 53792, USA.
authors.forename: Jon S
authors.initials: JS
authors.lastname: Odorico
mesh_terms: D048909:Diabetes Complications; D003922:Diabetes Mellitus, Type 1 / Q000150:complications / Q000601:surgery*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000601:surgery; D003928:Diabetic Nephropathies / Q000209:etiology / Q000601:surgery; D046148:Donor Selection; D006084:Graft Rejection / Q000517:prevention & control*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D016381:Islets of Langerhans Transplantation / Q000379:methods*; D007676:Kidney Failure, Chronic / Q000209:etiology / Q000601:surgery; D016030:Kidney Transplantation; D010179:Pancreas / Q000293:injuries; D016035:Pancreas Transplantation / Q000379:methods*; D050500:Pancreatitis, Chronic / Q000601:surgery; D018579:Patient Selection; D011183:Postoperative Complications; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents
keywords: Diabetes; Islet transplantation; Outcomes; Pancreas diseases; Pancreas transplantation