title: [Evaluation on Efficacy and Safety of Jinying Capsule in Treatment of Pelvic Inflammatory Disease Patients with Accumulated Damp-heat Syndrome].
abstract: OBJECTIVE
  To evaluate the efficacy and safety of Jinying Capsule (JC) in treating pelvic inflammatory disease patients with accumulated damp-heat syndrome (ADHS).
  
  
  METHODS
  Totally 328 patients were recruited in a prospective, positive drug parallel controlled, and multi-center clinical trial. Of them 213 patients in the treatment group took JC (0.5 g per capsule), 4 capsules each time, 3 times per day, while 115 patients in the control group took Kangfuyan Capsule (KC, 0.4 g per capsule), 3 capsules each time, twice per day. The course of treatment was 4 weeks for all. Scores of Chinese medical syndromes, visual analogue scale (VAS) of the lower abdominal pain, and European quality of life-five dimension scale (EQ-5D) were observed before treatment and after 4 weeks of treatment.
  
  
  RESULTS
  There were 204 patients in the treatment group and 109 in the control group who completed this trial. The total effective rate of Chinese medical syndrome was 89.71% (183/204 cases) in the treatment group and 76.15% (83/109 cases) in the control group (P < 0.01). Compared with before treatment in the same group, EQ-5D scores increased, and VAS scores of the lower abdominal pain decreased in the two groups after treatment. EQ-5D scores was 0.857 ± 0.157 in the treatment group, obviously higher than that in the control group (0.753 ± 0.126, P < 0.05). VAS scores of the lower abdominal pain was 2.14 ± 1.23 in the treatment group, lower than that in the control group (2.33 ± 1.24), but with no statistical difference between the two groups (P > 0.05). No adverse reaction occurred in the two groups.
  
  
  CONCLUSIONS
  JC was superior to KC in improving Chinese medical syndrome and quality of life of pelvic inflammatory disease patients with accumulated damp-heat syndrome.
authors.forename: Qin
authors.initials: Q
authors.lastname: Li
authors.forename: Chun-yan
authors.initials: CY
authors.lastname: Chen
authors.forename: Yu-ping
authors.initials: YP
authors.lastname: Suo
authors.forename: Min
authors.initials: M
authors.lastname: Huang
authors.forename: Xian-hua
authors.initials: XH
authors.lastname: Huang
mesh_terms: D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005260:Female; D006358:Hot Temperature; D006801:Humans; D008516:Medicine, Chinese Traditional; D000292:Pelvic Inflammatory Disease / Q000188:drug therapy*; D008517:Phytotherapy; D011446:Prospective Studies; D011788:Quality of Life; D012449:Safety; D013577:Syndrome
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal