title: Current Diagnostic and Therapeutic Aspects of Eosinophilic Myocarditis.
abstract: Eosinophilic myocarditis (EM) represents a rare form of myocardial inflammation with very heterogeneous aetiology. In developed countries, the most prevalent causes of EM are hypersensitivity or allergic reactions, as well as hematological diseases leading to eosinophilia. The disease may have a variable clinical presentation, ranging from asymptomatic forms to life-threatening conditions. Most patients with EM have marked eosinophilia in peripheral blood. Endomyocardial biopsy needs to be performed in most cases in order to establish a definitive diagnosis of EM. The therapy depends on the underlying aetiology. Immunosuppressive therapy represents the treatment mainstay in the majority of EM forms.
authors.affiliation: 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Kuchynka
authors.affiliation: 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Tomas
authors.initials: T
authors.lastname: Palecek
authors.affiliation: Department of Radiology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Martin
authors.initials: M
authors.lastname: Masek
authors.affiliation: Department of Radiology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Cerny
authors.affiliation: Department of Radiology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Lukas
authors.initials: L
authors.lastname: Lambert
authors.affiliation: Institute of Pathology, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Ivana
authors.initials: I
authors.lastname: Vitkova
authors.affiliation: 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, U Nemocnice 2, 128 08 Prague 2, Czech Republic.
authors.forename: Ales
authors.initials: A
authors.lastname: Linhart
mesh_terms: D001706:Biopsy; D004802:Eosinophilia / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D004804:Eosinophils / Q000473:pathology*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007249:Inflammation / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology; D009205:Myocarditis / Q000175:diagnosis / Q000188:drug therapy* / Q000276:immunology / Q000473:pathology
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents