title: Shen's Whole-Layer Tightly Appressed Anastomosis Technique for Duct-to-Mucosa Pancreaticojejunostomy in Pancreaticoduodenectomy.
abstract: BACKGROUND Postoperative pancreatic fistulas (POPFs) due to anastomotic leaks are always closely related to significant morbidity and mortality following pancreaticoduodenectomy (PD). A series of modified anastomotic methods have been proposed. The object of our study was to provide a novel anastomotic method for operations involving the Child technique, termed the "whole-layer tightly appressed anastomosis technique". MATERIAL AND METHODS An improved pancreatic whole-layer suture technique was used when we performed the duct-to-mucosa pancreaticojejunostomies; this method ensured the tight joining of the pancreatic stump and jejunum and decreased the pinholes in the pancreatic stump. This new method was used in 41 patients, and was compared with the traditional duct-to-mucosa anastomosis technique that was used in 50 patients as controls. RESULTS The POPF rate was much lower in the new method group than in the control group (6, 14.63% and 20, 40.00%, respectively, P=0.010). There were 5 grade A POPF patients and 1 grade B POPF patient in the study group. In the control group there were 12 grade A POPFs patients, 7 grade B POPFs patients, and 1 grade C POPF patient. The study group exhibited a lower morbidity rate (7, 17.07% vs. 16, 32.00%, P=0.022) and a reduced hospital stay (17.16 d vs. 22.92 d, P=0.001). CONCLUSIONS The whole-layer tightly appressed anastomosis technique presented in our study is a safer anastomotic method than the traditional duct-to-mucosa pancreaticojejunostomy technique. This new technique effectively reduced the incidence of POPF after PD and decreased the postoperative morbidity.
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Tian
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Xinjing
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Zhen
authors.initials: Z
authors.lastname: Huo
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Yuan
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Jiabin
authors.initials: J
authors.lastname: Jin
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Qian
authors.initials: Q
authors.lastname: Zhan
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Xiaxing
authors.initials: X
authors.lastname: Deng
authors.affiliation: Department of General Surgery, Rui Jin Hospital Affiliated to Shanghai Jiao Tong University, School of Medicine, Shanghai, China (mainland).
authors.forename: Baiyong
authors.initials: B
authors.lastname: Shen
mesh_terms: D000714:Anastomosis, Surgical / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D015994:Incidence; D007430:Intraoperative Care; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D009092:Mucous Membrane / Q000601:surgery*; D010183:Pancreatic Ducts / Q000601:surgery*; D010185:Pancreatic Fistula / Q000453:epidemiology / Q000401:mortality / Q000601:surgery; D016577:Pancreaticoduodenectomy / Q000009:adverse effects / Q000379:methods*; D010193:Pancreaticojejunostomy / Q000009:adverse effects / Q000379:methods*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D012307:Risk Factors