title: Next generation sequencing of the NOTCH3 gene in a cohort of pulmonary hypertension patients.
authors.affiliation: Genética Molecular-Laboratorio de Medicina, Hospital Universitario Central Asturias, Oviedo, Spain.
authors.forename: Juan
authors.initials: J
authors.lastname: Gómez
authors.affiliation: Cardiología-Fundación Asturcor, Hospital Universitario Central Asturias, Oviedo, Spain.
authors.forename: Julian R
authors.initials: JR
authors.lastname: Reguero
authors.affiliation: Cardiología-Fundación Asturcor, Hospital Universitario Central Asturias, Oviedo, Spain.
authors.forename: Manuel R
authors.initials: MR
authors.lastname: Junquera
authors.affiliation: Neumología, Hospital Universitario Central Asturias, Oviedo, Spain.
authors.forename: Celso
authors.initials: C
authors.lastname: Alvarez
authors.affiliation: Cardiología-Fundación Asturcor, Hospital Universitario Central Asturias, Oviedo, Spain; Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain.
authors.forename: César
authors.initials: C
authors.lastname: Morís
authors.affiliation: Genética Molecular-Laboratorio de Medicina, Hospital Universitario Central Asturias, Oviedo, Spain.
authors.forename: Belén
authors.initials: B
authors.lastname: Alonso
authors.affiliation: Genética Molecular-Laboratorio de Medicina, Hospital Universitario Central Asturias, Oviedo, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Iglesias
authors.affiliation: Genética Molecular-Laboratorio de Medicina, Hospital Universitario Central Asturias, Oviedo, Spain; Departamento de Medicina, Universidad de Oviedo, Oviedo, Spain. Electronic address: eliecer.coto@sespa.es.
authors.forename: Eliecer
authors.initials: E
authors.lastname: Coto
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods; D006801:Humans; D006976:Hypertension, Pulmonary / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D020125:Mutation, Missense; D000071656:Receptor, Notch3 / Q000235:genetics*; D017422:Sequence Analysis, DNA / Q000379:methods
chemical_list: C499374:NOTCH3 protein, human; D000071656:Receptor, Notch3
keywords: Gene mutation; NOTCH3 gene; Next generation sequencing; Pulmonary hypertension