title: Isoprenylated Flavonoids with PTP1B Inhibition from Ficus tikoua.
abstract: Two new isoprenylated flavanones, ficustikousins A and B (1 and 2), together with seven known compounds (3-9) were isolated from the whole plant of Ficus tikoua (Moraceae). The structures of the new compounds were elucidated on the basis of spectroscopic methods. Compounds 1-7 exhibited moderate inhibitory activities against PTP1B in vitro.
authors.forename: Lu-Qin
authors.initials: LQ
authors.lastname: Wu
authors.forename: Chun
authors.initials: C
authors.lastname: Lei
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Gao
authors.forename: Hai-Bing
authors.initials: HB
authors.lastname: Liao
authors.forename: Jing-Ya
authors.initials: JY
authors.lastname: Li
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.forename: Ai-Jun
authors.initials: AJ
authors.lastname: Hou
mesh_terms: D030681:Ficus / Q000737:chemistry*; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology*; D020128:Inhibitory Concentration 50; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1 / Q000037:antagonists & inhibitors*
chemical_list: D005419:Flavonoids; C000606173:ficustikousin A; C000606174:ficustikousin B; D054562:Protein Tyrosine Phosphatase, Non-Receptor Type 1