title: Synthesis of a Series of γ-Keto Allyl Phosphonates.
abstract: Under solvent-free conditions and at 80 °C, a DMAP- or imidazole-mediated clean and rapid conversion of cyclic Morita-Baylis-Hillman (MBH) acetates into the corresponding γ-keto allyl phosphonates in 70-93% yields is described herein. This allylic nucleophilic substitution works well with primary and secondary acetates bearing, at the β'-position, linear or branched alkyl groups and aryl groups.
authors.affiliation: Université de Tunis El Manar , Faculté des Sciences de Tunis, Laboratoire de Chimie Organique Structurale LR99ES14, Campus Universitaire, 2092 Tunis, Tunisia.
authors.forename: Haitham
authors.initials: H
authors.lastname: Elleuch
authors.affiliation: Université de Tunis El Manar , Faculté des Sciences de Tunis, Laboratoire de Chimie Organique Structurale LR99ES14, Campus Universitaire, 2092 Tunis, Tunisia.
authors.forename: Marwa
authors.initials: M
authors.lastname: Ayadi
authors.affiliation: Université de Toulouse 3, Université Paul-Sabatier , Faculté des Sciences Pharmaceutiques, Laboratoire des IMRCP UMR CNRS 5623, 35 chemin des Maraîchers, 31062 Toulouse cedex 09, France.
authors.forename: Jalloul
authors.initials: J
authors.lastname: Bouajila
authors.affiliation: Université de Tunis El Manar , Faculté des Sciences de Tunis, Laboratoire de Chimie Organique Structurale LR99ES14, Campus Universitaire, 2092 Tunis, Tunisia.
authors.forename: Farhat
authors.initials: F
authors.lastname: Rezgui