title: Prevalence of mcr-1 in commensal Escherichia coli from French livestock, 2007 to 2014.
abstract: Colistin resistance was investigated in 1,696 isolates collected from 2007 to 2014 within the frame of the French livestock antimicrobial resistance surveillance programme. The mcr-1 gene was detected in all commensal Escherichia coli isolates with a minimum inhibitory concentration to colistin above the 2 mg/L cut-off value (n=23). In poultry, mcr-1 prevalence was 5.9% in turkeys and 1.8% in broilers in 2014. In pigs, investigated in 2013, this prevalence did not exceed 0.5%. These findings support that mcr-1 has spread in French livestock.
authors.affiliation: ANSES, Laboratoire de Fougères, Fougères, France.
authors.forename: Agnès
authors.initials: A
authors.lastname: Perrin-Guyomard
authors.forename: Mireille
authors.initials: M
authors.lastname: Bruneau
authors.forename: Pamela
authors.initials: P
authors.lastname: Houée
authors.forename: Karine
authors.initials: K
authors.lastname: Deleurme
authors.forename: Patricia
authors.initials: P
authors.lastname: Legrandois
authors.forename: Catherine
authors.initials: C
authors.lastname: Poirier
authors.forename: Christophe
authors.initials: C
authors.lastname: Soumet
authors.forename: Pascal
authors.initials: P
authors.lastname: Sanders
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D003091:Colistin / Q000494:pharmacology*; D024881:Drug Resistance, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects* / Q000235:genetics / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000097:blood* / Q000188:drug therapy / Q000453:epidemiology / Q000382:microbiology; D005243:Feces / Q000382:microbiology; D005838:Genotype; D006801:Humans; D058751:Livestock; D008460:Meat / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D015995:Prevalence; D013552:Swine; D014422:Turkeys
chemical_list: D000900:Anti-Bacterial Agents; D003091:Colistin
keywords: Escherichia coli; antimicrobial resistance; colistin; surveillance