title: [Efficacy and safety analysis of surgical bypass and endovascular management in the treatment of 116 Takayasu arteritis].
abstract: OBJECTIVE
  To analyze the efficacy and safety of surgery and endovascular management in treating Takayasu arteritis.
  
  
  METHODS
  The data of 116 patients (24 males and 92 females; mean age (32±12) years) with Takayasu arteritis and underwent surgery or endovascular therapy was retrospective analyzed. According to the two different surgical procedures, the patients were divided into two groups: open repair group and endovascular repair group. One hundred and fifty-four surgical procedures were done including 69 cases of open repair and 85 cases of endovascular repair. A total of 211 arterial lesions were revascularized (open repair 114; endovascular repair 97).
  
  
  RESULTS
  Among the 154 surgical procedures, 11(7.1%) presented a complication during perioperative period including 6(8.7%) of open repair and 5(5.9%) of endovascular repair. After a median follow-up of 38.5(0.5-142.0) months, three(4.3%) cases of stroke and death were observed in open repair group, two(2.3%) cases of stroke and 4(4.7%) cases of death were observed in endovascular repair group. At 1, 3, 5 and 10 years of follow-up, primary patency rate of open repair and endovascular repair were 95.0% and 89.3%, 84.3% and 69.8%, 73.3% and 56.3%, 53.4% and 48.1%, respectively; Primary assisted patency rate were 100% and 97.5%, 90.4% and 78.2%, 79.1% and 72.8%, 60.7% and 54.0%, respectively; Secondary patency rate were 100% and 98.8%, 95.6% and 92.7%, 85.8% and 78.1%, 74.8% and 58.0%, respectively. Cumulative survival rate were 97.0% and 100%, 97.0% and 97.6%, 97.0% and 90.6%, 91.3% and 84.5%, respectively (χ(2)=0.182, P=0.669).
  
  
  CONCLUSIONS
  Both of the surgical revascularization and endovascular management are safe and effective in the treatment of Takayasu arteritis. Although long-term patency of endovascular therapy is low, it can be performed repeatedly and can be used as a preferred approach in treating a short stenosis. Surgical repair shows excellent long-term durability, it seems to be more suitable for complex lesions and failure cases of endovascular management.
authors.affiliation: Department of Vascular Surgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: Y P
authors.initials: YP
authors.lastname: Diao
authors.affiliation: Department of Vascular Surgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.
authors.forename: Y X
authors.initials: YX
authors.lastname: Chen
authors.forename: S
authors.initials: S
authors.lastname: Yan
authors.forename: Z G
authors.initials: ZG
authors.lastname: Chen
authors.forename: Q
authors.initials: Q
authors.lastname: Miao
authors.forename: X R
authors.initials: XR
authors.lastname: Liu
authors.forename: C W
authors.initials: CW
authors.lastname: Liu
authors.forename: Y J
authors.initials: YJ
authors.lastname: Li
mesh_terms: D000328:Adult; D019917:Blood Vessel Prosthesis Implantation; D003251:Constriction, Pathologic; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D059035:Perioperative Period; D012086:Reoperation; D012189:Retrospective Studies; D013625:Takayasu Arteritis / Q000601:surgery*; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000379:methods*; D055815:Young Adult