title: Application of modern computer-aided technologies in the production of individual bone graft: A case report.
abstract: BACKGROUND
  An autologous bone (bone derived from the patient himself) is considered to be a "golden standard" in the treatment of bone defects and partial atrophic alveolar ridge. However, large defects and bone losses are difficult to restore in this manner, because extraction of large amounts of autologous tissue can cause donor-site problems. Alternatively, data from computed tomographic (CT) scan can be used to shape a precise 3D homologous bone block using a computer-aided design-computer-aided manufacturing (CAD-CAM) system.
  
  
  METHODS
  A 63-year old male patient referred to the Clinic of Dentistry of Vojvodina in Novi Sad, because of teeth loss in the right lateral region of the lower jaw. Clinical examination revealed a pronounced resorption of the residual ridge of the lower jaw in the aforementioned region, both horizontal and vertical. After clinical examination, the patient was referred for 3D cone beam (CB)CT scan that enables visualization of bony structures and accurate measurement of dimensions of the residual alveolar ridge. Considering the large extent of bone resorption, the required ridge augmentation was more than 3 mm in height and 2 mm in width along the length of some 2 cm, thus the use of granular material was excluded. After consulting prosthodontists and engineers from the Faculty of Technical Sciences in Novi Sad we decided to fabricate an individual (custom) bovine-derived bone graft designed according to the obtained-3D CBCT scan.
  
  
  CONCLUSIONS
  Application of 3D CBCT images, computer-aided systems and software in manufacturing custom bone grafts represents the most recent method of guided bone regeneration. This method substantially reduces time of recovery and carries minimum risk of postoperative complications, yet the results fully satisfy the requirements of both the patient and the therapist.
authors.forename: Sinisa
authors.initials: S
authors.lastname: Mirković
authors.forename: Igor
authors.initials: I
authors.lastname: Budak
authors.forename: Tatjana
authors.initials: T
authors.lastname: Puskar
authors.forename: Ana
authors.initials: A
authors.lastname: Tadić
authors.forename: Mario
authors.initials: M
authors.lastname: Sokac
authors.forename: Zeljko
authors.initials: Z
authors.lastname: Santosi
authors.forename: Tatjana
authors.initials: T
authors.lastname: Djurdjević-Mirković
mesh_terms: D016301:Alveolar Bone Loss / Q000000981:diagnostic imaging / Q000601:surgery*; D000818:Animals; D016025:Bone Transplantation / Q000295:instrumentation* / Q000379:methods; D002417:Cattle; D017076:Computer-Aided Design; D054893:Cone-Beam Computed Tomography; D003758:Dental Implantation, Endosseous / Q000295:instrumentation* / Q000379:methods; D015921:Dental Implants; D064593:Heterografts; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000601:surgery*; D008875:Middle Aged; D011237:Predictive Value of Tests; D011474:Prosthesis Design; D011857:Radiographic Image Interpretation, Computer-Assisted; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants