title: Petchienes A-E, Meroterpenoids from Ganoderma petchii.
abstract: Petchienes A-E (1-5), five new meroterpenoids, were isolated from the fruiting bodies of Ganoderma petchii. Their structures, including absolute configurations, were elucidated by means of spectroscopic and computational methods. Compound 4 was isolated as a racemic mixture, which was finally purified by chiral HPLC to yield individual (-) and (+)-antipodes. Biological evaluation showed that compounds 2 and (-)-4 could increase intracellular free calcium concentration at 10 μM in HEK-293 cells.
authors.forename: Qin-Lei
authors.initials: QL
authors.lastname: Gao
authors.forename: Ping-Xia
authors.initials: PX
authors.lastname: Guo
authors.forename: Qi
authors.initials: Q
authors.lastname: Luo
authors.forename: Hui
authors.initials: H
authors.lastname: Yan
authors.forename: Yong-Xian
authors.initials: YX
authors.lastname: Cheng
mesh_terms: D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D032902:Ganoderma / Q000737:chemistry*; D015394:Molecular Structure; D013729:Terpenes / Q000737:chemistry* / Q000302:isolation & purification*
chemical_list: D013729:Terpenes