title: [31P Magnetic Resonance Spectroscopy in Patients With Various Genesis of Left Ventricular Hypertrophy].
abstract: OBJECTIVE
  to assess status of myocardial energy metabolism in patients with different etiology of left ventricular hypertrophy by phosphorus magnetic resonance spectroscopy (MRS) compared with healthy individuals.
  
  
  METHODS
  The study included 94 people: 30 healthy volunteers (group 1), 35 patients with arterial hypertension and left ventricular hypertrophy (group II), 29 patients with hypertrophic cardiomyopathy (group III). All persons underwent cardiac magnetic resonance imaging (MRI) and MRS on high field MR scanner. Energy metabolism index (ratio of phosphocreatine and adenosine triphosphate concentrations [Pcr/ATP]) was used for evaluation of myocardial energy metabolism.
  
  
  RESULTS
  Values of Pcr/ATP were 2.11 ± 0.29, 1.65 ± 0.12, and 1.32 ± 0.16 in groups I, II, and III, respectively (p < 0.05).
  
  
  CONCLUSIONS
  31P MRS is an effective tool of detection of disordered energy metabolism in hypertrophic myocardium. Combined use of MRI and MRS can become an effective method of comprehensive study of the heart.
authors.forename: S K
authors.initials: SK
authors.lastname: Ternovoy
authors.forename: V V
authors.initials: VV
authors.lastname: Mazaev
authors.forename: O V
authors.initials: OV
authors.lastname: Stukalova
authors.forename: N S
authors.initials: NS
authors.lastname: Serova
mesh_terms: D000255:Adenosine Triphosphate / Q000378:metabolism*; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D017379:Hypertrophy, Left Ventricular / Q000378:metabolism*; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009206:Myocardium / Q000378:metabolism*; D010725:Phosphocreatine / Q000378:metabolism*
chemical_list: D010725:Phosphocreatine; D000255:Adenosine Triphosphate