title: Reasons to Investigate the Soluble Receptor for Advanced Glycation End-Product (sRAGE) Pathway in Aortic Disease.
abstract: Aortic disease has a high rate of morbidity and mortality, and there are no documented screening methods to date. Yet biochemical research does show a significant link between soluble receptor for advanced glycation end-products (sRAGE) protein and cardiovascular disease. Therefore, it can be hypothesized that sRAGE plasma levels may help differentiate patients with aortic disease from the general population, which this paper will review and present.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Sarkar
authors.affiliation: Department of Physiology, College of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada; and.
authors.forename: Kailash
authors.initials: K
authors.lastname: Prasad
authors.forename: Bulat A
authors.initials: BA
authors.lastname: Ziganshin
authors.affiliation: Aortic Institute at Yale-New Haven Hospital, Yale University School of Medicine, New Haven, Connecticut;
authors.forename: John A
authors.initials: JA
authors.lastname: Elefteriades
keywords: Aortic aneurysm; Aortic disease; Screening biomarker; sRAGE