title: Stem cell secretome-rich nanoclay hydrogel: a dual action therapy for cardiovascular regeneration.
abstract: A nanocomposite hydrogel with photocrosslinkable micro-porous networks and a nanoclay component was successfully prepared to control the release of growth factor-rich stem cell secretome. The proven pro-angiogenic and cardioprotective potential of this new bioactive system provides a valuable therapeutic platform for cardiac tissue repair and regeneration.
authors.affiliation: BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA. arghyapaul@ku.edu.
authors.forename: Renae
authors.initials: R
authors.lastname: Waters
authors.affiliation: BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA. arghyapaul@ku.edu.
authors.forename: Settimio
authors.initials: S
authors.lastname: Pacelli
authors.affiliation: BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA. arghyapaul@ku.edu.
authors.forename: Ryan
authors.initials: R
authors.lastname: Maloney
authors.affiliation: SRM University, Kattankulathur 603203, Tamilnadu, India.
authors.forename: Indrani
authors.initials: I
authors.lastname: Medhi
authors.affiliation: Department of Pathology, University of Cincinnati, 231-Albert Sabin Way, Cincinnati 45267, OH, USA.
authors.forename: Rafeeq P H
authors.initials: RP
authors.lastname: Ahmed
authors.affiliation: BioIntel Research Laboratory, Department of Chemical and Petroleum Engineering, Bioengineering Graduate Program, School of Engineering, University of Kansas, Lawrence, KS, USA. arghyapaul@ku.edu.
authors.forename: Arghya
authors.initials: A
authors.lastname: Paul
mesh_terms: D000538:Aluminum Silicates / Q000737:chemistry*; D018929:Cell Culture Techniques; D002478:Cells, Cultured; D000077215:Clay; D006801:Humans; D020100:Hydrogels / Q000737:chemistry*; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000378:metabolism*; D009206:Myocardium / Q000166:cytology / Q000378:metabolism; D049329:Nanostructures / Q000737:chemistry*; D044968:Regenerative Medicine
chemical_list: D000538:Aluminum Silicates; D020100:Hydrogels; D036341:Intercellular Signaling Peptides and Proteins; D000077215:Clay