title: Place of diagnostic tools in the identification of Anaerobiospirillum succiniciproducens bacteraemia.
abstract: Anaerobiospirillum succiniciproducens is a rare but potentially lethal pathogen. We report a case of A. succiniciproducens bloodstream infection in a 55-year-old man hospitalized for pelvic trauma. The strain was identified by 16sRNA sequencing after several failures of identification by MALDI-TOF MS. The strain was susceptible to beta-lactam antibiotics and ciprofloxacin, but resistant to macrolides and clindamycin. Identification tools must be improved to enhance our knowledge on this rare pathogen and to define optimal therapy.
authors.affiliation: Department of Bacteriology, Amiens University Hospital, Amiens, France; Microbiology Research Unit, EA4294, Jules Verne University of Picardie, France. Electronic address: decroix.veronique@chu-amiens.fr.
authors.forename: V
authors.initials: V
authors.lastname: Decroix
authors.affiliation: Department of Bacteriology, Amiens University Hospital, Amiens, France.
authors.forename: E
authors.initials: E
authors.lastname: Pluquet
authors.affiliation: Department of Bacteriology, Amiens University Hospital, Amiens, France.
authors.forename: M
authors.initials: M
authors.lastname: Choquet
authors.affiliation: Intensive Care Unit, Amiens University Hospital, Amiens, France.
authors.forename: N
authors.initials: N
authors.lastname: Ammenouche
authors.affiliation: Department of Bacteriology, Amiens University Hospital, Amiens, France; Microbiology Research Unit, EA4294, Jules Verne University of Picardie, France.
authors.forename: S
authors.initials: S
authors.lastname: Castelain
authors.affiliation: Department of Bacteriology, Amiens University Hospital, Amiens, France; Microbiology Research Unit, EA4294, Jules Verne University of Picardie, France.
authors.forename: R
authors.initials: R
authors.lastname: Guiheneuf
mesh_terms: D044064:Anaerobiospirillum / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002939:Ciprofloxacin / Q000627:therapeutic use; D002981:Clindamycin / Q000627:therapeutic use; D057210:Delayed Diagnosis; D024881:Drug Resistance, Bacterial; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D010388:Pelvis / Q000293:injuries; D012336:RNA, Ribosomal, 16S / Q000235:genetics*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D047090:beta-Lactams / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D012336:RNA, Ribosomal, 16S; D047090:beta-Lactams; D002981:Clindamycin; D002939:Ciprofloxacin
keywords: 16s rRNA sequencing; Anaerobiospirillum succiniciproducens; Bacteraemia; Gram-negative anaerobic; Rod-shaped bacteria