title: Effect of inhaled steroids on laryngeal microflora.
abstract: Conclusions As is known, this study is the first study to evaluate the effect of inhaled steroids on laryngeal microflora. The data support that ICS usage causes changes in the larynx microflora. Purpose The aim of this study was to determine the alteration in larynx microbial flora of the patients treated with ICS comparing the culture results of a control group. In addition, laryngeal microflora was compared to the smears obtained from the vallecula and pharynx. Materials and methods The study included 39 patients (mean age = 45.56 ± 12.76 years) who had been using a corticosteroid inhaler and control group consisting of 27 persons (mean age = 43.07 ± 13.23 years). Culture samples were obtained from the pharynx, larynx, and vallecula in the patient and control groups, and they were evaluated in the microbiology laboratory. Obtained culture results were named by the same microbiologist according to the basic microorganism classification method. Results Coagulase-negative staphylococci (CNS), Streptococcus viridians (VGS) and candida albicans were detected to grow significantly more in the patient group in all three anatomic localizations compared to the control group. Neisseria spp, basillus spp, and Non-viridans alpha-hemolytic streptococcus were detected to grow significantly more in the control group in all three anatomic localizations compared to the patient group.
authors.affiliation: a Department of Otorhinolaryngology , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Mahfuz
authors.initials: M
authors.lastname: Turan
authors.affiliation: b Department of Chest Disease , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Selami
authors.initials: S
authors.lastname: Ekin
authors.affiliation: c Department of Endocrinology and Metabolism , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Rıfkı
authors.initials: R
authors.lastname: Ucler
authors.affiliation: b Department of Chest Disease , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Ahmet
authors.initials: A
authors.lastname: Arısoy
authors.affiliation: d Department of Medical Microbiology , Yuzuncu Yil University Faculty of Medicine , Van , Turkey.
authors.forename: Yasemin
authors.initials: Y
authors.lastname: Bayram
authors.affiliation: a Department of Otorhinolaryngology , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Abdulaziz
authors.initials: A
authors.lastname: Yalınkılıç
authors.affiliation: a Department of Otorhinolaryngology , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Nazım
authors.initials: N
authors.lastname: Bozan
authors.affiliation: a Department of Otorhinolaryngology , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Mehmet Fatih
authors.initials: MF
authors.lastname: Garca
authors.affiliation: a Department of Otorhinolaryngology , Yuzuncu Yil University Faculty of Medicine , Van , Turkey ;
authors.forename: Hakan
authors.initials: H
authors.lastname: Çankaya
mesh_terms: D000280:Administration, Inhalation; D000305:Adrenal Cortex Hormones / Q000009:adverse effects*; D000328:Adult; D005260:Female; D006801:Humans; D007830:Larynx / Q000187:drug effects / Q000382:microbiology*; D008297:Male; D008875:Middle Aged; D010614:Pharynx / Q000382:microbiology; D011446:Prospective Studies
chemical_list: D000305:Adrenal Cortex Hormones
keywords: Inhaled steroids; larynx; microflora