title: Hematopoietic stem cell transplantation in Europe 2014: more than 40 000 transplants annually.
abstract: A record number of 40 829 hematopoietic stem cell transplantation (HSCT) in 36 469 patients (15 765 allogeneic (43%), 20 704 autologous (57%)) were reported by 656 centers in 47 countries to the 2014 survey. Trends include: continued growth in transplant activity, more so in Eastern European countries than in the west; a continued increase in the use of haploidentical family donors (by 25%) and slower growth for unrelated donor HSCT. The use of cord blood as a stem cell source has decreased again in 2014. Main indications for HSCT were leukemias: 11 853 (33%; 96% allogeneic); lymphoid neoplasias; 20 802 (57%; 11% allogeneic); solid tumors; 1458 (4%; 3% allogeneic) and non-malignant disorders; 2203 (6%; 88% allogeneic). Changes in transplant activity include more allogeneic HSCT for AML in CR1, myeloproliferative neoplasm (MPN) and aplastic anemia and decreasing use in CLL; and more autologous HSCT for plasma cell disorders and in particular for amyloidosis. In addition, data on numbers of teams doing alternative donor transplants, allogeneic after autologous HSCT, autologous cord blood transplants are presented.
authors.affiliation: EBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital Basel, Basel, Switzerland.
authors.forename: J R
authors.initials: JR
authors.lastname: Passweg
authors.affiliation: EBMT Activity Survey Office, Division of Hematology, Department of Medicine, University Hospital Basel, Basel, Switzerland.
authors.forename: H
authors.initials: H
authors.lastname: Baldomero
authors.affiliation: Klinik für Kinder- und Jugendmedizin, Universitätsklinikum Frankfurt, Goethe-Universität, Frankfurt am Main, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Bader
authors.affiliation: Università Vita-Salute San Raffaele, Milan, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Bonini
authors.affiliation: Paediatric Haematology Oncology, Policlinico G.B. Rossi, Verona, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Cesaro
authors.affiliation: Medizinische Klinik V, University of Heidelberg, Heidelberg, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Dreger
authors.affiliation: Hematology Department, Institut Català d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
authors.forename: R F
authors.initials: RF
authors.lastname: Duarte
authors.affiliation: Hematology Unit, G.Gaslini Children's Institute, Genova, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Dufour
authors.affiliation: Department of Haematology, University Medical Centre, Utrecht, The Netherlands.
authors.forename: J
authors.initials: J
authors.lastname: Kuball
authors.affiliation: Service de Médecine Interne, Maladies Autoimmunes et Pathologie Vasculaire, Hôpital St Louis, Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Farge-Bancel
authors.affiliation: Paediatric Team Children's BMT Unit, Great North Children's Hospital, Royal Victoria Infirmary, Newcastle University, Newcastle-Upon-Tyne, UK.
authors.forename: A
authors.initials: A
authors.lastname: Gennery
authors.affiliation: Department of Stem cell Transplantation, University Hospital Eppendorf, Hamburg, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Kröger
authors.affiliation: Hematology and BMT Unit, Cremona, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Lanza
authors.affiliation: Chaim Sheba Medical Center, Tel-Hashomer, Israel.
authors.forename: A
authors.initials: A
authors.lastname: Nagler
authors.affiliation: Hematology Department, Institut Català d'Oncologia, Hospital Duran I Reynals, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Sureda
authors.affiliation: Department of Hematology, Hôpital Saint Antoine, Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Mohty
mesh_terms: D000686:Amyloidosis / Q000628:therapy; D000741:Anemia, Aplastic / Q000628:therapy; D036101:Cord Blood Stem Cell Transplantation / Q000706:statistics & numerical data; D005060:Europe; D018380:Hematopoietic Stem Cell Transplantation / Q000379:methods / Q000706:statistics & numerical data* / Q000639:trends; D006801:Humans; D009369:Neoplasms / Q000628:therapy; D010348:Patient Care Team / Q000706:statistics & numerical data / Q000639:trends; D011795:Surveys and Questionnaires; D014019:Tissue Donors / Q000706:statistics & numerical data; D014182:Transplantation, Autologous; D000075442:Transplantation, Haploidentical; D014184:Transplantation, Homologous