title: Evidence for Vertical Transmission of Novel Duck-Origin Goose Parvovirus-Related Parvovirus.
abstract: In 2015, novel duck-origin goose parvovirus-related parvovirus (N-GPV) infection progressively appeared in commercial Cherry Valley duck flocks in North China. Diseased ducks were observed to have beak atrophy and dwarfism syndrome (BADS). A previous study showed that a high seropositive rate for N-GPV indicated a latent infection in most breeder duck flocks. To investigate this possibility in hatching eggs collected from N-GPV-infected breeder ducks, 120 eggs were collected at various stages of embryonic development for viral DNA detection and an N-GPV-specific antibody test. N-GPV DNA was present in nine hatching eggs, eleven duck embryo and eight newly hatched ducklings. Of the newly hatched ducklings, 58.33% (21/36) were seropositive. Further, two isolates were obtained from a 12-day-old duck embryo and a newly hatched duckling. N-GPV infection did not reduce the fertilization rate and hatchability. These results indicate possible vertical transmission of N-GPV and suggest that it may be transmitted from breeder ducks to ducklings in ovo.
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong, China.
authors.forename: H
authors.initials: H
authors.lastname: Chen
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Tang
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Dou
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong, China.
authors.forename: X
authors.initials: X
authors.lastname: Zheng
authors.affiliation: College of Animal Science and Technology, Shandong Agricultural University, Tai'an, Shandong, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Diao
mesh_terms: D000818:Animals; D036022:Capsid Proteins / Q000235:genetics; D002681:China / Q000453:epidemiology; D004372:Ducks; D018445:Infectious Disease Transmission, Vertical / Q000662:veterinary*; D010063:Ovum / Q000821:virology; D010322:Parvoviridae Infections / Q000453:epidemiology / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D019219:Parvovirinae / Q000235:genetics / Q000502:physiology*; D010802:Phylogeny; D011201:Poultry Diseases / Q000453:epidemiology / Q000635:transmission* / Q000821:virology; D015995:Prevalence; D017422:Sequence Analysis, DNA / Q000662:veterinary; D016036:Seroepidemiologic Studies
chemical_list: D036022:Capsid Proteins
keywords: duck embryo; iELISA; novel GPV-related parvovirus; vertical transmission