title: Biomaterials and host versus graft response: a short review.
abstract: Biomaterials and biotechnology are increasing becoming an important area in modern medicine. The main aim in this area is the development of materials, which are biocompatible to normal tissue. Tissue-implant interactions with molecular, biological and cellular characteristics at the implant-tissue interface are important for the use and development of implants. Implantation may cause an inflammatory and immune response in tissue, foreign body reaction, systemic toxicity and imminent infection. Tissue-implant interactions determine the implant life-period. The aims of the study are to consider the biological response to implants. Biomaterials and host reactions to implants and their mechanisms are also briefly discussed.
authors.affiliation: University Medical Centre Maribor, Department of Neurosurgery. tvelnar@hotmail.com.
authors.forename: Tomaz
authors.initials: T
authors.lastname: Velnar
authors.forename: Gorazd
authors.initials: G
authors.lastname: Bunc
authors.forename: Robert
authors.initials: R
authors.lastname: Klobucar
authors.forename: Lidija
authors.initials: L
authors.lastname: Gradisnik
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000009:adverse effects*; D005549:Foreign-Body Reaction; D006086:Graft vs Host Disease / Q000209:etiology* / Q000276:immunology; D006801:Humans; D008422:Materials Testing; D019736:Prostheses and Implants
chemical_list: D001672:Biocompatible Materials