title: Addressing diabetes mellitus as part of the strategy for ending TB.
abstract: As we enter the new era of Sustainable Development Goals, the international community has committed to ending the TB epidemic by 2030 through implementation of an ambitious strategy to reduce TB-incidence and TB-related mortality and avoiding catastrophic costs for TB-affected families. Diabetes mellitus (DM) triples the risk of TB and increases the probability of adverse TB treatment outcomes such as failure, death and recurrent TB. The rapidly escalating global epidemic of DM means that DM needs to be addressed if TB-related milestones and targets are to be achieved. WHO and the International Union Against Tuberculosis and Lung Disease's Collaborative Framework for Care and Control of Tuberculosis and Diabetes, launched in 2011, provides a template to guide policy makers and implementers to combat the epidemics of both diseases. However, more evidence is required to answer important questions about bi-directional screening, optimal ways of delivering treatment, integration of DM and TB services, and infection control. This should in turn contribute to better and earlier TB case detection, and improved TB treatment outcomes and prevention. DM and TB collaborative care can also help guide the development of a more effective and integrated public health approach for managing non-communicable diseases.
authors.affiliation: International Union Against Tuberculosis and Lung Disease, Paris, France London School of Hygiene and Tropical Medicine, Keppel Street, London, UK adharries@theunion.org.
authors.forename: Anthony D
authors.initials: AD
authors.lastname: Harries
authors.affiliation: International Union Against Tuberculosis and Lung Disease, South-East Asia Regional Office, New Delhi, India.
authors.forename: Ajay M V
authors.initials: AM
authors.lastname: Kumar
authors.affiliation: International Union Against Tuberculosis and Lung Disease, South-East Asia Regional Office, New Delhi, India.
authors.forename: Srinath
authors.initials: S
authors.lastname: Satyanarayana
authors.affiliation: China Office, International Union Against Tuberculosis and Lung Disease, Beijing, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Lin
authors.affiliation: Médecins sans Frontières, Medical Department, Operational Research Unit, Brussels Operational Center, Luxembourg City, Luxembourg.
authors.forename: Rony
authors.initials: R
authors.lastname: Zachariah
authors.affiliation: Global TB Programme, World Health Organization, Geneva, Switzerland Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Knut
authors.initials: K
authors.lastname: Lönnroth
authors.affiliation: World Diabetes Foundation, Gentofte, Denmark.
authors.forename: Anil
authors.initials: A
authors.lastname: Kapur
mesh_terms: D003299:Cooperative Behavior; D019033:Delivery of Health Care, Integrated / Q000458:organization & administration / Q000592:standards; D048909:Diabetes Complications / Q000517:prevention & control; D003920:Diabetes Mellitus / Q000175:diagnosis / Q000517:prevention & control*; D042241:Early Diagnosis; D006801:Humans; D008403:Mass Screening / Q000458:organization & administration; D011634:Public Health; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis / Q000517:prevention & control*
keywords: Bi-directional screening; Diabetes mellitus; End TB Strategy; Prevention of latent TB; Treatment outcomes; Tuberculosis