title: THE ROLE OF CANDIDA IN INTESTINAL DYSBACTERIOSIS FORMATION.
abstract: BACKGROUND
  In modern TB chemotherapy until today retains a leading role in the treatment of tuberculosis patients, and specific nature of the inflammatory process, its course and symptoms include the duration and continuity of chemotherapy. It is known that prolonged chemotherapy naturally leads a large majority (92.0%) of patients in the development of intestinal dysbiosis, where the leading role in the microbial imbalance is a deficiency or complete absence of bifidobacteria, it creates conditions for the settlement of fungi Candida, also plays a major role in microbial associations.
  
  
  OBJECTIVE
  Examine the role of candida in intestinal dysbacteriosis formation.
  
  
  METHODS
  The 500 patients with various forms of pulmonary tuberculosis were examined for reveal intestinal dysbiosis, which conducted bacteriological examination of feces for intestinal dysbiosis method RV Epstein-Litvak FL Vilshanskoy.
  
  
  RESULTS
  In great majority of patients (92%), the long chemotherapy naturally leads to conclusions development of intestines dysbacteriosis. The leading value in a microbial imbalance belongs to deficiency or total absence of the bifidobacterium, which creates conditions for Candida, and plays the main part in microbial associations. There was noted a high therapeutic efficiency of the pathogenic agents antifungal drugs, allowing to eliminate Candida intestinal dysbacteriosis of patients suffered from pulmonary tuberculosis.
authors.forename: Z E
authors.initials: ZE
authors.lastname: Lineva
authors.forename: N A
authors.initials: NA
authors.lastname: Gulyaeva
authors.forename: M V
authors.initials: MV
authors.lastname: Romanova
authors.forename: P S
authors.initials: PS
authors.lastname: Dyachkovskaya
mesh_terms: D000995:Antitubercular Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D002175:Candida / Q000302:isolation & purification*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000209:etiology; D064806:Dysbiosis / Q000139:chemically induced / Q000209:etiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007410:Intestinal Diseases / Q000175:diagnosis / Q000382:microbiology*; D008297:Male; D014397:Tuberculosis, Pulmonary / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents