title: [A Decrease in Lung Cancer Mortality Following the Implementation of CT Screening for General Population].
abstract: In Hitachi Medical Area, a large-scale lung cancer screening program using low-dose CT has been underway in two medical facilities since its introduction in 1998 and 2001. A total of 61,914 tests were performed among 25,385 participants until 2006. Two hundred and ten lung cancer patients had been identified on CT screening. The estimated 5-year survival rate for all patients was 90%. Among residents in Hitachi City, nearly 40% of inhabitants aged 50-69 years were estimated to have participated in the screening from 1998 through 2009. Cancer mortality data were obtained from a regional cancer registry and the standardized mortality ratio (SMR) of lung cancer was calculated for each 5-year period during 1995-2009. For residents aged 50-79 years, SMR was nearly unity between 1995 and 2004; however, there was a significant decrease during 2005-2009, with SMR (95% confidence interval) being 0.76 (0.67-0.86). These results suggest that the wide implementation of CT screening may reduce lung cancer mortality in the community, 4-8 years after introduction. It is desirable to continue to focus on future developments, including original research in Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nawa
mesh_terms: D000368:Aged; D055088:Early Detection of Cancer / Q000706:statistics & numerical data; D005260:Female; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008175:Lung Neoplasms / Q000401:mortality* / Q000473:pathology / Q000517:prevention & control*; D008297:Male; D008403:Mass Screening / Q000706:statistics & numerical data* / Q000639:trends; D008875:Middle Aged; D009367:Neoplasm Staging; D013902:Radiography, Thoracic; D013997:Time Factors; D014057:Tomography, X-Ray Computed