title: Toxic epidermal necrolysis associated with radiotherapy and phenytoin in a patient with non-Hodking's lymphoma: A case report.
abstract: Toxic epidermal necrolysis (TEN) is a disease which is characterized by fever and desquamation of the skin and mucosal membranes. It is usually related with drugs, especially aromatic anticonvulsants which are recognized as the most common cause of this disorder. Cranial irradiation may act as a precipitating factor along with anticonvulsants for the development of TEN. We report a 28-year-old patient with central nervous system (CNS) relapsed non-Hodgkin lymphoma (NHL) who developed TEN after cranial radiotherapy and concurrent phenytoin treatment.
authors.affiliation: Ege University, School of Medicine, Department of Internal Medicine, Izmir, Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Keklik
authors.affiliation: Department of Hematology, Izmir, Turkey.
authors.forename: Melda Cömert
authors.initials: MC
authors.lastname: Özkan
authors.affiliation: Department of Dermatology, Izmir, Turkey.
authors.forename: Gizem Kocabaş
authors.initials: GK
authors.lastname: Yenipazar
authors.affiliation: Department of Pathology, Izmir, Turkey.
authors.forename: Banu
authors.initials: B
authors.lastname: Yaman
authors.affiliation: Department of Hematology, Izmir, Turkey.
authors.forename: Güray
authors.initials: G
authors.lastname: Saydam
authors.affiliation: Department of Hematology, Izmir, Turkey.
authors.forename: Fahri
authors.initials: F
authors.lastname: Şahin
keywords: Fenitoin; Radiotherapy; Toxic epidermal necrolysis