title: Complications of Immunosuppressive Therapy in Solid Organ Transplantation.
abstract: Availability of novel immunosuppressive drugs is the most important factor responsible for significant improvement in long-term graft survival rates after solid organ transplantation. However, chronic immunosuppression predisposes patients to a myriad of potentially life-threatening complications. In addition to drug-related adverse effects, transplant recipients are at increased risk of developing opportunistic microbial infections and a spectrum of unique cancers, many of which are caused by oncogenic viruses. Cross-sectional imaging studies play a crucial role in the timely diagnosis and management of post-transplant infections and malignancies.
authors.affiliation: Department of Radiology, University of Texas Health Science Center, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
authors.forename: Venkata
authors.initials: V
authors.lastname: Katabathina
authors.affiliation: Department of Radiology, Mayo Clinic, 13400 E Shea Blvd, Scottsdale, AZ 85259, USA.
authors.forename: Christine O
authors.initials: CO
authors.lastname: Menias
authors.affiliation: Department of Radiology, University of Wisconsin, G3/310 600 Highland Avenue, Madison, WI 53792, USA.
authors.forename: Perry
authors.initials: P
authors.lastname: Pickhardt
authors.affiliation: Department of Radiology, University of Wisconsin, G3/310 600 Highland Avenue, Madison, WI 53792, USA.
authors.forename: Meghan
authors.initials: M
authors.lastname: Lubner
authors.affiliation: Department of Radiology, University of Texas MD Anderson Cancer Center, 1400 Pressler Street, Houston, TX 77030, USA. Electronic address: sprasad2@mdanderson.org.
authors.forename: Srinivasa R
authors.initials: SR
authors.lastname: Prasad
mesh_terms: D003952:Diagnostic Imaging; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D008232:Lymphoproliferative Disorders / Q000175:diagnosis* / Q000209:etiology*; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology*; D012307:Risk Factors; D014180:Transplantation
keywords: Complications; Computed tomography; Immunosuppression; Infections; MR imaging; Malignancy; Posttransplant lymphoproliferative disorder (PTLD); Transplantation