title: Screening for hepatocellular carcinoma in high-risk populations.
abstract: Screening for hepatocellular carcinoma (HCC) should be implemented in the high-risk population. High-risk population includes patients with cirrhosis of any etiology, patients with chronic hepatitis B virus with or without cirrhosis, and patients with chronic hepatitis C virus with cirrhosis. A randomized controlled trial of over 18,000 high-risk individuals demonstrated that biannual screening reduced HCC-related mortality by 37%. The screening test of choice is ultrasound imaging with an interval of 6 months.
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, NY 10065.
authors.forename: Zoe A
authors.initials: ZA
authors.lastname: Miller
authors.affiliation: Department of Radiology, Weill Cornell Medical College, New York, NY 10065. Electronic address: ksl2001@med.cornell.edu.
authors.forename: Kyungmouk Steve
authors.initials: KS
authors.lastname: Lee
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000175:diagnosis* / Q000453:epidemiology; D055088:Early Detection of Cancer / Q000379:methods*; D014943:Global Health; D006801:Humans; D008113:Liver Neoplasms / Q000175:diagnosis* / Q000453:epidemiology; D008297:Male; D009017:Morbidity / Q000639:trends; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends
keywords: Cirrhosis; Hepatitis B; Hepatitis C; Hepatocellular carcinoma screening; Liver cancer screening