title: Reflex operculoinsular seizures.
abstract: Activation of specific cortical territories by certain stimuli is known to trigger focal seizures. We report three cases of well documented operculo-insular reflex seizures, triggered by somatosensory stimuli in two and loud noises in the third. Limited operculoinsular resection resulted in an excellent outcome for all. We discuss these observations in regard to the literature on reflex epilepsy and known functions of the insula. [Published with video sequences online].
authors.affiliation: Division of Neurology, CHUM Notre-Dame, Université de Montréal, Montreal, Canada.
authors.forename: Handsun
authors.initials: H
authors.lastname: Xiao
authors.affiliation: Division of Neurology, CHUM Notre-Dame, Université de Montréal, Montreal, Canada, Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
authors.forename: Thi Phuoc Yen
authors.initials: TP
authors.lastname: Tran
authors.affiliation: Division of Neurology, CHUM Notre-Dame, Université de Montréal, Montreal, Canada.
authors.forename: Myriam
authors.initials: M
authors.lastname: Pétrin
authors.affiliation: Department of Psychology, Université de Montréal, Montreal.
authors.forename: Olivier
authors.initials: O
authors.lastname: Boucher
authors.affiliation: Division of Neurology, IWK Health Center, Dalhousie University, Halifax.
authors.forename: Ismail
authors.initials: I
authors.lastname: Mohamed
authors.affiliation: Division of Neurosurgery, CHUM Notre-Dame, Université de Montréal, Montreal, Canada.
authors.forename: Alain
authors.initials: A
authors.lastname: Bouthillier
authors.affiliation: Division of Neurology, CHUM Notre-Dame, Université de Montréal, Montreal, Canada.
authors.forename: Dang Khoa
authors.initials: DK
authors.lastname: Nguyen
mesh_terms: D000328:Adult; D002540:Cerebral Cortex / Q000503:physiopathology*; D003937:Diagnosis, Differential; D004569:Electroencephalography / Q000379:methods; D020195:Epilepsy, Reflex / Q000175:diagnosis / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012018:Reflex / Q000502:physiology*; D012640:Seizures / Q000175:diagnosis / Q000503:physiopathology*
keywords: audiogenic; epilepsy; insula; reflex; somatosensory