title: Nasal basal cell carcinomas. Can we reduce surgical margins to 3mm with complete excision?
abstract: BACKGROUND
  The purpose of this study was to evaluate the incomplete excision rate of nasal basal cell carcinomas (BCC) resected with different margins to demonstrate that 3-mm surgical margins could be used as safety margins to reduce esthetic consequences with a low risk of incomplete excision.
  
  
  METHODS
  All patients with BCC of the nose excised from January 1st 2008 to December 31st 2011 were included. Data were analyzed and reviewed retrospectively. Tumors were treated with different surgical margins of excision: 3mm, 4mm, and 5mm. The primary outcome variable was the rate of incomplete excision. Other study variables were the histologic subtype, size, and recurrent lesions.
  
  
  RESULTS
  Of the 132 patients, 115 were included corresponding on with 127 BCC. Median age was 75.5 (64-83) and sex ratio M:F=1.05. Of the 127 BCC, 80 were aggressive histologic subtype (63%), and 11 were recurrent (8.7%). The overall rate of incomplete excision was 17.3% (n=22). Of these 22, 17 (77.3%) were of an aggressive subtype. The incomplete excision rates within the groups were 12.5% (n=4), 22.2% (n=10), and 16% (n=8), respectively within the group with 3-, 4- and 5-mm surgical margins. No significant difference was observed between the groups (P=.519). The incomplete excision rate was not independently associated with the surgical margins, histologic subtype and recurrent type (P>.05).
  
  
  CONCLUSIONS
  Three-millimeters margins could possibly be used to treat nasal BCC in chosen cases. Regarding the high rate of incomplete excision, reconstruction should be performed after receiving the pathologic report.
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, centre hospitalier universitaire Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France. Electronic address: sandra.konopnicki@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Konopnicki
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, centre hospitalier universitaire Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: O
authors.initials: O
authors.lastname: Hermeziu
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, centre hospitalier universitaire Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: R
authors.initials: R
authors.lastname: Bosc
authors.affiliation: Service d'anatomopathologie, centre hospitalier intercommunal de Créteil, 40, avenue de Verdun, 94010 Créteil, France.
authors.forename: I
authors.initials: I
authors.lastname: Abd Alsamad
authors.affiliation: Service de chirurgie plastique reconstructrice et esthétique, centre hospitalier universitaire Henri-Mondor, AP-HP, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Meningaud
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D000072662:Margins of Excision; D008875:Middle Aged; D009669:Nose Neoplasms / Q000473:pathology / Q000601:surgery*; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*
keywords: Basal cell carcinomas; Carcinomes basocellulaires; Chirurgie carcinologique; Incomplete excision rate; Marges chirurgicales; Nose neoplasms; Surgical excision; Surgical margins; Taux d’exérèse incomplète; Tumeurs du nez