title: Intravenous labetolol in treating hypertensive crisis following dexmedetomidine infusion for procedural sedation.
abstract: Dexmedetomidine is widely used for procedural sedation because of its unique combination of sedation, analgesia, and anxiolysis with minimal respiratory depression. Transient hypertension has been reported during the use of dexmedetomidine which is usually benign and is taken over by the hypotensive response on continuing the infusion. We report a case of hypertensive crisis following dexmedetomidine infusion used for procedural sedation, necessitating discontinuation of the infusion and treatment of hypertension. The dilemmas involved in treating hypertension caused by dexmedetomidine are discussed.
authors.affiliation: Department of Anaesthesiology and Critical Care, Chettinad Hospital and Research Institute, Kelambakkam, 603103, India. Electronic address: thilaks84@gmail.com.
authors.forename: Thilaka
authors.initials: T
authors.lastname: Muthiah
authors.affiliation: Department of Anaesthesiology and Critical Care, Chettinad Hospital and Research Institute, Kelambakkam, 603103, India. Electronic address: moni.amarnath@gmail.com.
authors.forename: Amarnath
authors.initials: A
authors.lastname: Moni
authors.affiliation: Department of Anaesthesiology and Critical Care, Chettinad Hospital and Research Institute, Kelambakkam, 603103, India. Electronic address: lailu.mathews@gmail.com.
authors.forename: Lailu
authors.initials: L
authors.lastname: Mathews
authors.affiliation: Department of Anaesthesiology and Critical Care, Chettinad Hospital and Research Institute, Kelambakkam, 603103, India. Electronic address: leu.sudarshan@gmail.com.
authors.forename: Sudarshan
authors.initials: S
authors.lastname: Balaji
mesh_terms: D058647:Adrenergic alpha-2 Receptor Agonists / Q000009:adverse effects; D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use*; D016292:Procedural Sedation / Q000009:adverse effects; D020927:Dexmedetomidine / Q000009:adverse effects*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy*; D006993:Hypnotics and Sedatives / Q000009:adverse effects*; D007741:Labetalol / Q000627:therapeutic use*; D008297:Male
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D000959:Antihypertensive Agents; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine; D007741:Labetalol
keywords: Dexmedetomidine; Hypertension; Labetolol; Sedation