title: Jasmonate-responsive transcription factors regulating plant secondary metabolism.
abstract: Plants produce a large variety of secondary metabolites including alkaloids, glucosinolates, terpenoids and phenylpropanoids. These compounds play key roles in plant-environment interactions and many of them have pharmacological activity in humans. Jasmonates (JAs) are plant hormones which induce biosynthesis of many secondary metabolites. JAs-responsive transcription factors (TFs) that regulate the JAs-induced accumulation of secondary metabolites belong to different families including AP2/ERF, bHLH, MYB and WRKY. Here, we give an overview of the types and functions of TFs that have been identified in JAs-induced secondary metabolite biosynthesis, and highlight their similarities and differences in regulating various biosynthetic pathways. We review major recent developments regarding JAs-responsive TFs mediating secondary metabolite biosynthesis, and provide suggestions for further studies.
authors.affiliation: Institute of Biology, Leiden University, Sylvius Laboratory, P.O. Box 9505, 2300 RA, Leiden, The Netherlands; Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: zhml39@hotmail.com.
authors.forename: Meiliang
authors.initials: M
authors.lastname: Zhou
authors.affiliation: Biotechnology Research Institute, Chinese Academy of Agricultural Sciences, Beijing 100081, China. Electronic address: j.memelink@biology.leidenuniv.nl.
authors.forename: Johan
authors.initials: J
authors.lastname: Memelink
mesh_terms: D003517:Cyclopentanes / Q000378:metabolism / Q000494:pharmacology; D054883:Oxylipins / Q000378:metabolism / Q000494:pharmacology; D010944:Plants / Q000187:drug effects / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000187:drug effects / Q000378:metabolism / Q000502:physiology
chemical_list: D003517:Cyclopentanes; D054883:Oxylipins; D014157:Transcription Factors; C011006:jasmonic acid
keywords: JAZ; Jasmonate; ORCA; Transcription factor; bHLH