title: Therapeutic Potential of Neuregulin in Cardiovascular System: Can we Ignore the Effects of Neuregulin on Electrophysiology?
abstract: Neuregulin-1(NRG-1) has now been accepted to have therapeutic potential in cardiovascular disease. The preclinical and clinical researches of NRG-1 have demonstrated its advantage effects in cardiac function with multi-target cardiovascular biology and pathophysiology, but its influence on cardiac electrophysiology is rarely involved, which is a very important aspect and should not be ignored.
authors.affiliation: Department of Cardiology, Renmin Hospital of Wuhan University, Cardiovascular Research Institute, Wuhan University, Wuhan, China. xiwangwhu@163.com.
authors.forename: Xi
authors.initials: X
authors.lastname: Wang
authors.forename: Zhiqiang
authors.initials: Z
authors.lastname: Liu
authors.forename: Hui Nan
authors.initials: HN
authors.lastname: Duan
authors.affiliation: Cardiovascular Research Institute, Wuhan University, Wuhan, China, Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, China. wanglongwhu@163.com.
authors.forename: Long
authors.initials: L
authors.lastname: Wang
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism / Q000503:physiopathology*; D016757:Death, Sudden, Cardiac / Q000209:etiology; D004594:Electrophysiology; D014644:Genetic Variation; D006321:Heart / Q000187:drug effects* / Q000294:innervation / Q000503:physiopathology*; D006801:Humans; D017136:Ion Transport / Q000187:drug effects; D009206:Myocardium / Q000378:metabolism; D020890:Neuregulin-1 / Q000235:genetics / Q000378:metabolism* / Q000627:therapeutic use*; D011994:Recombinant Proteins / Q000235:genetics / Q000378:metabolism / Q000627:therapeutic use
chemical_list: C094131:NRG1 protein, human; D020890:Neuregulin-1; D011994:Recombinant Proteins