title: Serum Resistin Levels May Contribute to an Increased Risk of Acute Cerebral Infarction.
abstract: The objective of this study was to investigate the association between serum resistin levels and acute cerebral infarction (ACI). PubMed, SpringerLink, Wiley, EBSCO, Ovid, Web of Science, Wanfang, China National Knowledge Infrastructure, and VIP databases (last updated search in October 2014) were exhaustively searched, and data from the eligible studies were extracted and analyzed to assess the association between serum resistin levels and ACI. STATA software (version 12.0, Stata Corporation, College Station, TX, USA) was utilized for data analysis. Ten studies including 1829 ACI patients and 1557 healthy controls were eligible for inclusion in the meta-analysis. Our major result revealed that ACI patients exhibited higher serum resistin levels compared with healthy controls. Asubgroup analysis based on ethnicity showed a significant association between serum resistin levels and ACI in Asians, but surprisingly not in Caucasians. The results of our meta-analysis suggest that serum resistin levels are associated with an increased risk of ACI.
authors.affiliation: Department of Neurology, Tangshan People's Hospital, No. 65 Shengli Road, Lunan District, Tangshan, 063000, People's Republic of China. dongxiaoliu_dr@yeah.net.
authors.forename: Xiao-Liu
authors.initials: XL
authors.lastname: Dong
authors.affiliation: Department of Neurology, Tangshan People's Hospital, No. 65 Shengli Road, Lunan District, Tangshan, 063000, People's Republic of China.
authors.forename: Shi-Jun
authors.initials: SJ
authors.lastname: Xu
authors.affiliation: Department of Neurosurgery, Tangshan People's Hospital, Tangshan, 063000, People's Republic of China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Neurology, Tangshan People's Hospital, No. 65 Shengli Road, Lunan District, Tangshan, 063000, People's Republic of China.
authors.forename: Xiu-Qing
authors.initials: XQ
authors.lastname: Zhang
authors.affiliation: Department of Neurology, Tangshan People's Hospital, No. 65 Shengli Road, Lunan District, Tangshan, 063000, People's Republic of China.
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.affiliation: Department of Ultrasonic Medicine, Tangshan People's Hospital, Tangshan, 063000, People's Republic of China.
authors.forename: Qiu-Yan
authors.initials: QY
authors.lastname: Gao
authors.affiliation: Department of Neurology, Affiliated Tangshan Gongren Hospital of North China University of Science and Technology, Tangshan, 063000, People's Republic of China.
authors.forename: Qing-Qiang
authors.initials: QQ
authors.lastname: Qian
authors.affiliation: Key Lab of Cerebral Microcirculation in Universities of Shandong, Taishan Medical University, Taian, 271000, People's Republic of China.
authors.forename: Bao-Liang
authors.initials: BL
authors.lastname: Sun
authors.affiliation: Key Lab of Cerebral Microcirculation in Universities of Shandong, Taishan Medical University, Taian, 271000, People's Republic of China.
authors.forename: Ming-Feng
authors.initials: MF
authors.lastname: Yang
mesh_terms: D000208:Acute Disease; D044466:Asian People / Q000208:ethnology; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D002544:Cerebral Infarction / Q000097:blood* / Q000175:diagnosis* / Q000208:ethnology; D006801:Humans; D052243:Resistin / Q000097:blood*; D012307:Risk Factors; D044465:White People / Q000208:ethnology
chemical_list: D015415:Biomarkers; C499624:RETN protein, human; D052243:Resistin
keywords: Acute cerebral infarction; Acute cerebrovascular disease; Acute stroke; Adipocyte-specific secretory factor; Found in inflammatory zone 3; Resistin