title: The impact of spectral filtration on image quality in micro-CT system.
abstract: This paper aims to evaluate the impact of spectral filtration on image quality in a microcomputed tomography (micro-CT) system. A mouse phantom comprising 11rods for modeling lung, muscle, adipose, and bones was scanned with 17 s and 2min, respectively. The current (μA) for each scan was adjusted to achieve identical entrance exposure to the phantom, providing a baseline for image quality evaluation. For each region of interest (ROI) within specific composition, CT number variations, noise levels, and contrast-to-noise ratios (CNRs) were evaluated from the reconstructed images. CT number variations and CNRs for bone with high density, muscle, and adipose were compared with theoretical predictions. The results show that the impact of spectral filtration on image quality indicators, such as CNR in a micro-CT system, is significantly associated with tissue characteristics. The findings may provide useful references for optimizing the scanning parameters of general micro-CT systems in future imaging applications.
authors.affiliation: University of Oklahoma. renliqiang@ou.edu.
authors.forename: Liqiang
authors.initials: L
authors.lastname: Ren
authors.forename: Muhammad U
authors.initials: MU
authors.lastname: Ghani
authors.forename: Di
authors.initials: D
authors.lastname: Wu
authors.forename: Bin
authors.initials: B
authors.lastname: Zheng
authors.forename: Yong
authors.initials: Y
authors.lastname: Chen
authors.forename: Kai
authors.initials: K
authors.lastname: Yang
authors.forename: Xizeng
authors.initials: X
authors.lastname: Wu
authors.forename: Hong
authors.initials: H
authors.lastname: Liu
mesh_terms: D000818:Animals; D005374:Filtration; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D051379:Mice; D019047:Phantoms, Imaging; D011786:Quality Control; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D055114:X-Ray Microtomography / Q000379:methods*