title: Asthma in an Adult Female Vervet Monkey (Chlorocebus sabaeus).
abstract: A 9-y-old, colony-bred, female vervet monkey (Chlorocebus sabaeus) presented with a 6-y history of open-mouth breathing, tachypnea, and sibilant wheezing. These symptoms did not significantly affect her activity or quality of life. Thoracic radiographs and results of bronchoalveolar lavage supported the diagnosis of asthma. Treatment comprising intramuscular prednisolone (tapered over 2 mo from twice daily to every other day), inhaled salmeterol-fluticasone (25 μg-250 μg per actuation twice daily) by mask, and a metered dose inhaler was successful in restoring a normal respiratory pattern. Despite the availability of several primate models of human asthma, this case represents the first report of spontaneous asthma in a NHP.
authors.affiliation: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies. lkoster@rossvet.edu.kn.
authors.forename: Liza S
authors.initials: LS
authors.lastname: Köster
authors.affiliation: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies; Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A and M University, College Station, Texas, USA.
authors.forename: Bradley
authors.initials: B
authors.lastname: Simon
authors.affiliation: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies.
authors.forename: Gilda
authors.initials: G
authors.lastname: Rawlins
authors.affiliation: Department of Clinical Sciences, Ross University School of Veterinary Medicine, St Kitts and Nevis, West Indies; Behavioural Science Foundation, St Kitts, West Indies.
authors.forename: Amy
authors.initials: A
authors.lastname: Beierschmitt
mesh_terms: D000280:Administration, Inhalation; D058666:Adrenergic beta-2 Receptor Agonists / Q000008:administration & dosage; D000367:Age Factors; D000818:Animals; D018927:Anti-Asthmatic Agents / Q000008:administration & dosage; D001249:Asthma / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000662:veterinary*; D018893:Bronchoalveolar Lavage / Q000662:veterinary; D001993:Bronchodilator Agents / Q000008:administration & dosage; D002522:Chlorocebus aethiops; D005260:Female; D000068297:Fluticasone-Salmeterol Drug Combination / Q000008:administration & dosage; D005938:Glucocorticoids / Q000008:administration & dosage; D007273:Injections, Intramuscular; D008168:Lung / Q000000981:diagnostic imaging / Q000187:drug effects / Q000503:physiopathology; D008992:Monkey Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D011239:Prednisolone / Q000008:administration & dosage; D013902:Radiography, Thoracic / Q000662:veterinary; D012129:Respiratory Function Tests / Q000662:veterinary; D016896:Treatment Outcome
chemical_list: D058666:Adrenergic beta-2 Receptor Agonists; D018927:Anti-Asthmatic Agents; D001993:Bronchodilator Agents; D000068297:Fluticasone-Salmeterol Drug Combination; D005938:Glucocorticoids; D011239:Prednisolone