title: Imaging synucleinopathies.
abstract: In this review the structural and functional imaging changes associated with the synucleinopathies PD, MSA, and dementias associated with Lewy bodies are reviewed. The role of imaging for supporting differential diagnosis, detecting subclinical disease, and following disease progression is discussed and its potential use for monitoring disease progression is debated. © 2016 International Parkinson and Movement Disorder Society.
authors.affiliation: Dept of Nuclear Medicine, Institute of Clinical Medicine, Aarhus University, Aarhus, Denmark.|Dept of Medicine, Imperial College London, London, United Kingdom.|Division of Neurology, Newcastle University, Newcastle, United Kingdom.
authors.forename: David J
authors.initials: DJ
authors.lastname: Brooks
authors.affiliation: Dept of Neurology, Azienda Ospedaliera e Universitaria di Perugia, Perugia, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Tambasco
mesh_terms: D006801:Humans; D020961:Lewy Body Disease / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D019578:Multiple System Atrophy / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D010300:Parkinson Disease / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D013378:Substantia Nigra / Q000000981:diagnostic imaging / Q000378:metabolism / Q000473:pathology; D051844:alpha-Synuclein / Q000378:metabolism*
chemical_list: D051844:alpha-Synuclein
keywords: DLB; MRI; MSA; PET; Parkinson's; SPECT