title: Epidemiological and Clinical Characteristics of Kawasaki Disease and Factors Associated with Coronary Artery Abnormalities in East China: Nine Years Experience.
abstract: BACKGROUND
  Because of the different genetic backgrounds, living environments and economic conditions, the epidemiologic, clinical characteristics and risk factors for coronary artery abnormalities (CAAs) in the Chinese population may differ among different parts of China.
  
  
  METHODS
  We did a retrospective study to explore the clinical characteristics and risk factors for CAAs in east China between 2006 and 2014.
  
  
  RESULTS
  There were 1016 patients during the study period. Of the 1004 patients who completed echocardiographic studies, 23.9% had CAAs. Sex, serum albumin, erythrocyte sedimentation rate (ESR),Mycoplasma pneumoniae(MP) infection, intravenous immunoglobulin (IVIG) started after the 10th day of illness and IVIG non-responders were independent risk factors associated with CAA.
  
  
  CONCLUSIONS
  East China has a lower incidence of CAAs compared with southwest and northeast China, while similar to north China. Male gender, serum albumin, ESR, MP infection, IVIG started after the 10th day of illness and IVIG non-responders were predictive of CAA.
authors.affiliation: Department of Cardiology, Children's Hospital of Soochow University, Suzhou, 215003 China.
authors.forename: Yunjia
authors.initials: Y
authors.lastname: Tang
authors.affiliation: Department of Pediatrics, the First People's Hospital of Wujiang, Jiangsu, 215200 China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Gao
authors.affiliation: Department of Cardiology, Children's Hospital of Soochow University, Suzhou, 215003 China.
authors.forename: Jie
authors.initials: J
authors.lastname: Shen
authors.affiliation: Department of Cardiology, Children's Hospital of Soochow University, Suzhou, 215003 China.
authors.forename: Ling
authors.initials: L
authors.lastname: Sun
authors.affiliation: Department of Cardiology, Children's Hospital of Soochow University, Suzhou, 215003 China whyan328@sina.com.
authors.forename: Wenhua
authors.initials: W
authors.lastname: Yan
mesh_terms: D015415:Biomarkers / Q000097:blood*; D001792:Blood Platelets; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000209:etiology*; D003330:Coronary Vessel Anomalies / Q000453:epidemiology*; D004452:Echocardiography; D005260:Female; D006454:Hemoglobins; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000008:administration & dosage; D007223:Infant; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology*; D012189:Retrospective Studies; D012307:Risk Factors; D012709:Serum Albumin / Q000032:analysis
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D016756:Immunoglobulins, Intravenous; D012709:Serum Albumin; D002097:C-Reactive Protein
keywords: Kawasaki disease; coronary artery abnormalities; east China; factors