title: Improved low-cost, MR-compatible olfactometer to deliver tobacco smoke odor.
abstract: We describe a low-cost, MRI-compatible olfactometer that delivers fresh cigarette smoke odor, a challenging odorant to present, as well as other odorants. This new olfactometer retains all of the advantages of an earlier design that was capable of only delivering volatile odors (Lowen & Lukas, Behavior Research Methods, 38, 307-313, 2006). The new system incorporates a novel switching mechanism that allows it to deliver fresh smoke generated from a burning cigarette during a stimulus presentation paradigm that might be employed in a cue-reactivity experiment. An evaluation study established that the olfactometer reliably delivered smoke to the participants and that tobacco smoke was discriminated from other odorants; there were no adverse reactions to the device.
authors.affiliation: McLean Imaging Center, McLean Hospital/Harvard Medical School, 115 Mill Street, Belmont, MA, 02478, USA. lowen@mclean.harvard.edu.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Lowen
authors.affiliation: McLean Imaging Center, McLean Hospital/Harvard Medical School, 115 Mill Street, Belmont, MA, 02478, USA.
authors.forename: Stacey L
authors.initials: SL
authors.lastname: Farmer
authors.affiliation: McLean Imaging Center, McLean Hospital/Harvard Medical School, 115 Mill Street, Belmont, MA, 02478, USA.
authors.forename: Scott E
authors.initials: SE
authors.lastname: Lukas
mesh_terms: D000280:Administration, Inhalation; D000328:Adult; D004192:Discrimination, Psychological; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009812:Odorants; D064367:Olfactometry / Q000191:economics / Q000295:instrumentation*; D012906:Smoke; D055815:Young Adult
chemical_list: D012906:Smoke
keywords: Cigarette; Cue reactivity; Drug cue; Odor; Olfaction; Smoke; fMRI