title: The Challenge of Pulmonary Nontuberculous Mycobacterial Infection.
abstract: The incidence of nontuberculous mycobacterial (NTM) lung disease is increasing. Current treatment strategies are largely based on expert opinion. The lack of randomized clinical trials to inform treatment leave clinicians with many questions regarding the most effective and safe regimens. The risk-benefit ratio of therapy is often thought to favor observation given the chronic nature of the disease, multiple long-term antibiotics recommended for therapy, side effects associated with treatment, and perceived lack of efficacious therapies.
authors.affiliation: Pulmonary & Critical Care Medicine Oregon Health & Science University 3181 SW Sam Jackson Park Road, UHN 67 Portland, OR, 97239 USA.
authors.forename: Shannon
authors.initials: S
authors.lastname: Novosad
authors.affiliation: School of medicine Public Health & Preventive Medicine Oregon Health & Science University 3181 SW Sam Jackson Park Road Portland, OR, 97239 USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Henkle
authors.affiliation: Department of Medicine Division of Infectious Diseases Oregon Health & Science University 3181 SW Sam Jackson Park Road Portland, OR, 97239 USA.
authors.forename: Kevin L
authors.initials: KL
authors.lastname: Winthrop
keywords: MAC; Mycobacterium abscessus; antibiotic resistance; nontuberculous mycobacterial (NTM) pulmonary disease; surgical therapy