title: Cannabis-induced psychosis associated with high potency "wax dabs".
abstract: With mounting evidence that the risk of cannabis-induced psychosis may be related to both dose and potency of tetrahydrocannbinol (THC), increasing reports of psychosis associated with cannabinoids containing greater amounts of THC are anticipated. We report two cases of emergent psychosis after using a concentrated THC extract known as cannabis "wax," "oil," or "dabs" raising serious concerns about its psychotic liability. Although "dabbing" with cannabis wax is becoming increasingly popular in the US for both recreational and "medicinal" intentions, our cases raise serious concerns about its psychotic liability and highlight the importance of understanding this risk by physicians recommending cannabinoids for purported medicinal purposes.
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California; Department of Veterans Affairs, VA Greater Los Angeles Healthcare System, Los Angeles, CA. Electronic address: joseph.pierre2@va.gov.
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Pierre
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, David Geffen School of Medicine at UCLA, Los Angeles, California.
authors.forename: Michael
authors.initials: M
authors.lastname: Gandal
authors.affiliation: College of Medicine, University of Vermont, Burlington, VT.
authors.forename: Maya
authors.initials: M
authors.lastname: Son
mesh_terms: D000293:Adolescent; D000328:Adult; D002188:Cannabis / Q000633:toxicity*; D003937:Diagnosis, Differential; D013759:Dronabinol / Q000633:toxicity*; D005500:Follow-Up Studies; D006801:Humans; D013287:Illicit Drugs / Q000633:toxicity*; D008297:Male; D002189:Marijuana Abuse / Q000150:complications* / Q000628:therapy; D010936:Plant Extracts / Q000633:toxicity*; D011605:Psychoses, Substance-Induced / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy
chemical_list: D013287:Illicit Drugs; D010936:Plant Extracts; D013759:Dronabinol
keywords: Cannabis; Cannabis oil; Cannabis wax; Cannabis-induced psychosis, catatonia; Marijuana; Tetrahydrocannabinol