title: Relation between the testicular sperm assay and sex hormone level in patients with azoospermia induced by mumps.
abstract: This study aimed to investigate the relation between the testicular sperm assay (TESA) and sex hormone level or testicular volume in patients with azoospermia induced by mumps. Samples from 52 patients with mumps-induced azoospermia were subjected to TESA, and then the sperm activity was observed microscopically. The sex hormone level was detected with an electrochemical assay, and ultrasound was used to calculate the testicular volume. Of the 52 azoospermia patients, 38 were found to have active sperms through testicular sperm extraction from the opened testis; furthermore, the serum follicle-stimulating hormone (FSH) and luteinizing hormone levels were obviously higher in the non-sperm group than in the sperm group (P < 0.05). Moreover, the testicular volume was smaller in the non-sperm group than in the sperm group; however, there was no significant difference between the two groups (P > 0.05). With the FSH value as a standard, the quantity of sperms was found to be within two times of, or more than two-fold of the normal range. With the testicular volume as a standard, sperms were found in testes with a volume of > 6 mL or < 6 mL. The FSH value and the testicular volume were indicators of the ability of the TESA to obtain sperms. To allow the performance of intracytoplasmic sperm injection, all patients need to undergo TESA.
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Shuiwen
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Yulin
authors.initials: Y
authors.lastname: An
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Junguo
authors.initials: J
authors.lastname: Li
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Junhong
authors.initials: J
authors.lastname: Guo
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Guoping
authors.initials: G
authors.lastname: Zhou
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Li
authors.affiliation: Reproductive Medical Center, The General Hospital of Beijing Military Region Beijing 100700, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Xu
keywords: Mumps; azoospermia; sex hormone; testis volume