title: Management of the Preterm Infant with Congenital Heart Disease.
abstract: The premature neonate with congenital heart disease (CHD) represents a challenging population for clinicians and researchers. The interaction between prematurity and CHD is poorly understood; epidemiologic study suggests that premature newborns are more likely to have CHD and that fetuses with CHD are more likely to be born premature. Understanding the key physiologic features of this special patient population is paramount. Clinicians have debated optimal timing for referral for cardiac surgery, and management in the postoperative period has rapidly advanced. This article summarizes the key concepts and literature in the care of the premature neonate with CHD.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, Stanford University Medical Center, 750 Welch Road, Suite 321, Palo Alto, CA 94304, USA. Electronic address: daxelrod@stanford.edu.
authors.forename: David M
authors.initials: DM
authors.lastname: Axelrod
authors.affiliation: Division of Neonatology, Department of Pediatrics, Stanford University Medical Center, 750 Welch Road, Suite 315, MC 5731, Palo Alto, CA 94304, USA.
authors.forename: Valerie Y
authors.initials: VY
authors.lastname: Chock
authors.affiliation: Pediatric Cardiothoracic Surgery, University of California San Francisco Medical Center, 550 16th Street, Floor 5, MH5-745, San Francisco, CA 94143-0117, USA.
authors.forename: V Mohan
authors.initials: VM
authors.lastname: Reddy
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000628:therapy; D006348:Cardiac Surgical Procedures; D002543:Cerebral Hemorrhage / Q000628:therapy; D019468:Disease Management; D020345:Enterocolitis, Necrotizing / Q000628:therapy; D005865:Gestational Age; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D052577:Infant, Extremely Low Birth Weight; D062071:Infant, Extremely Premature; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D007234:Infant, Premature; D007969:Leukomalacia, Periventricular / Q000628:therapy; D012178:Retinopathy of Prematurity / Q000628:therapy; D018805:Sepsis / Q000628:therapy; D061665:Time-to-Treatment
keywords: Cardiopulmonary bypass; Congenital heart disease; Congenital heart surgery; Low birth weight; Neonate; Prematurity