title: Influence of diffuse reflectance measurement accuracy on the scattering coefficient in determination of optical properties with integrating sphere optics (a secondary publication).
abstract: An estimation error of the scattering coefficient of hemoglobin in the high absorption wavelength range has been observed in optical property calculations of blood-rich tissues. In this study, the relationship between the accuracy of diffuse reflectance measurement in the integrating sphere and calculated scattering coefficient was evaluated with a system to calculate optical properties combined with an integrating sphere setup and the inverse Monte Carlo simulation. Diffuse reflectance was measured with the integrating sphere using a small incident port diameter and optical properties were calculated. As a result, the estimation error of the scattering coefficient was improved by accurate measurement of diffuse reflectance. In the high absorption wavelength range, the accuracy of diffuse reflectance measurement has an effect on the calculated scattering coefficient.
authors.affiliation: Medical Beam Physics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University.
authors.forename: Takuro
authors.initials: T
authors.lastname: Horibe
authors.affiliation: Medical Beam Physics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Ishii
authors.affiliation: Medical Beam Physics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University.
authors.forename: Daichi
authors.initials: D
authors.lastname: Fukutomi
authors.affiliation: Medical Beam Physics Laboratory, Division of Sustainable Energy and Environmental Engineering, Graduate School of Engineering, Osaka University; Graduate School of Frontier Biosciences, Osaka University; Global Center for Medical Engineering and Informatics, Osaka University.
authors.forename: Kunio
authors.initials: K
authors.lastname: Awazu
keywords: diffuse reflectance; estimation error; incident port diameter; integrating sphere setup; optical property; scattering coefficient