title: Pro-inflammatory cytokines: Useful markers for the diagnosis of canine mammary tumours?
abstract: The aim of the present study was to analyse the expression of 60 pro-inflammatory cytokines as possible markers of malignancy in canine mammary tumours using a human cytokine antibody array. The cytokines were grouped into two different categories: (1) cytokines in which expression indicated the presence of a mammary tumour and (2) cytokines in which expression differentiated between simple mammary adenoma, tubulopapillary carcinoma or complex carcinoma. These data suggest that specific pro-inflammatory cytokines could be useful as tools for the diagnosis of canine mammary tumours.
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, E-08193 Bellaterra, Barcelona, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Andaluz
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, E-08193 Bellaterra, Barcelona, Spain.
authors.forename: Marc
authors.initials: M
authors.lastname: Yeste
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, E-08193 Bellaterra, Barcelona, Spain.
authors.forename: Joan E
authors.initials: JE
authors.lastname: Rodríguez-Gil
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, E-08193 Bellaterra, Barcelona, Spain.
authors.forename: Teresa
authors.initials: T
authors.lastname: Rigau
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, E-08193 Bellaterra, Barcelona, Spain.
authors.forename: Félix
authors.initials: F
authors.lastname: García
authors.affiliation: Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, E-08193 Bellaterra, Barcelona, Spain. Electronic address: mariamontserrat.rivera@uab.cat.
authors.forename: Maria Montserrat
authors.initials: MM
authors.lastname: Rivera del Álamo
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000378:metabolism; D016207:Cytokines / Q000378:metabolism*; D004285:Dogs; D018836:Inflammation Mediators / Q000378:metabolism*; D008321:Mammary Glands, Animal / Q000378:metabolism; D015674:Mammary Neoplasms, Animal / Q000175:diagnosis* / Q000378:metabolism
chemical_list: D015415:Biomarkers; D016207:Cytokines; D018836:Inflammation Mediators
keywords: Canine mammary gland; Complex carcinoma; Pro-inflammatory cytokines; Simple adenoma; Tubulopapillary carcinoma