title: Genotoxicity Effects in Freshwater Fish from a Brazilian Impacted River.
abstract: This study evaluated the incidence of nuclear abnormalities (NA) in four fish species from an impacted river in Northeastern Brazil, characterized by accumulation of heavy metals and organic sewage. Two carnivores (Serrasalmus brandtii and Hoplias malabaricus) and two omnivore species (Oreochromis niloticus and Geophagus brasiliensis), used as food sources by local populations, were collected during the dry and the rainy season along Contas River basin. Nuclear abnormalities (bulbs, binuclei, lobes, micronuclei, notches, and vacuoles) were reported in all fish samples, with high occurrence in S. brandtii and H. malabaricus, species commonly found in local fish markets. This result agrees with previous analyses of accumulation of trace metals in both species, suggesting an association of genotoxic effects and biomagnification. Moreover, native specimens collected near urban areas presented higher frequencies of NA while O. niloticus seems to be more tolerant to environmental contamination. Therefore, effective policies are required to reduce the contamination of Contas River, since pollution by xenobiotics are potential threats to both local biodiversity and human population.
authors.affiliation: Department of Biological Sciences, Universidade Estadual do Sudoeste da Bahia, Av. José Moreira Sobrinho, s/n, Jequié, BA, 45206-190, Brazil. isac_msn@hotmail.com.
authors.forename: Isac Silva
authors.initials: IS
authors.lastname: de Jesus
authors.affiliation: Centro Politécnico, Universidade Federal do Paraná, Rua Francisco Heráclito dos Santos, 210, Jardim das Américas, Curitiba, PR, Brazil.
authors.forename: Marta Margarete
authors.initials: MM
authors.lastname: Cestari
authors.affiliation: Department of Chemistry and Exact Sciences, Universidade Estadual do Sudoeste da Bahia, Jequié, BA, Brazil.
authors.forename: Marcos de Almeida
authors.initials: Mde A
authors.lastname: Bezerra
authors.affiliation: Department of Biological Sciences, Universidade Estadual do Sudoeste da Bahia, Av. José Moreira Sobrinho, s/n, Jequié, BA, 45206-190, Brazil.
authors.forename: Paulo Roberto Antunes de Mello
authors.initials: PR
authors.lastname: Affonso
mesh_terms: D000818:Animals; D001938:Brazil; D002397:Catfishes / Q000235:genetics; D023681:Cichlids / Q000235:genetics; D004784:Environmental Monitoring / Q000379:methods*; D005399:Fishes / Q000235:genetics*; D006801:Humans; D019216:Metals, Heavy / Q000032:analysis / Q000633:toxicity; D048629:Micronuclei, Chromosome-Defective / Q000139:chemically induced*; D009153:Mutagens / Q000032:analysis / Q000633:toxicity*; D011891:Rain; D045483:Rivers / Q000737:chemistry*; D012621:Seasons; D012722:Sewage / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis / Q000633:toxicity*
chemical_list: D019216:Metals, Heavy; D009153:Mutagens; D012722:Sewage; D014874:Water Pollutants, Chemical
keywords: Biomagnification; Ecotoxicology; Micronuclei; Risk assessment