title: Unusual presentation of melanoma of unknown primary origin: A case report and review of literature.
abstract: Malignant melanomas often present with metastasis to regional lymph nodes. Patients are also known to present with metastatic nodes in the absence of a known primary. However metastatic melanoma involving the stomach is rare in the scenario of an unknown primary lesion. We present a case of a 41-year-old lady who was treated for nodal disease in the right axilla 8. months earlier with an unknown primary. She later presented to us with a recurrent right axillary swelling and on evaluation was found to also have a nodular deposit on the greater curvature of the stomach. Histopathology of the deposit in conjunction with immunohistochemical markers S.100P, Melan-A and HMB-45, confirmed the diagnosis of malignant melanoma. The patient underwent surgical excision of both lesions and is now on regular follow-up.
authors.forename: Sanket
authors.initials: S
authors.lastname: Bankar
authors.forename: Shraddha
authors.initials: S
authors.lastname: Patkar
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Desai
authors.affiliation: Department of Surgical Oncology, Tata Memorial Centre, Mumbai, Maharashtra, India.
authors.forename: Shailesh V
authors.initials: SV
authors.lastname: Shrikhande
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000378:metabolism*; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D008545:Melanoma / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D009382:Neoplasms, Unknown Primary / Q000378:metabolism / Q000473:pathology* / Q000601:surgery; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor