title: [The efficacy and safety of postoperative retransfusion drain following total hip arthroplasty: a Meta-analysis].
abstract: OBJECTIVE
  To investigate the effectiveness and safety of post-operative retransfusion drain(PRD) after total hip arthroplasty.
  
  
  METHODS
  A systematic literature review based on PubMed, EMBase, the Cochrane Library, China Biology Medicine disc, CNKI, VIP and WanFang Database in any language regarding PRD following total hip arthroplasty was performed.The data was evaluated using modified Jadad score and then analyzed using RevMan 5.2.
  
  
  RESULTS
  Nine randomized controlled trials totaling 1 824 patients, 913 patients in PRD group and 911 in control group, were eligible for data extraction and Meta-analysis.The results indicated that the use of PRD could reduce the requirement of allogeneic blood transfusion when compared with ordinary vacuum drainage (RR=0.61, 95% CI= 0.47-0.79), but the benefit was not found when compared with no drainage group(RR=1.07, 95% CI=0.67-1.71). And the postoperative hemoglobin level was higher in PRD group(MD=0.14, 95% CI=0.01-0.27, P=0.04). No significant difference was identified regarding transfusion index, length of hospital stay, the incidence of febrile reaction and wound-related complications.
  
  
  CONCLUSIONS
  PRD in reducing requirement of blood transfusion following THA is effective and safe when compared with ordinary vacuum drainage, but the benefit is not found when compared with no drainage.And more robust evidence is needed to confirm this result.
authors.affiliation: Department of Orthopaedic Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.
authors.forename: Jinwei
authors.initials: J
authors.lastname: Xie
authors.forename: Bin
authors.initials: B
authors.lastname: Xu
authors.forename: Pengde
authors.initials: P
authors.lastname: Kang
authors.forename: Zongke
authors.initials: Z
authors.lastname: Zhou
authors.forename: Bin
authors.initials: B
authors.lastname: Shen
authors.forename: Jing
authors.initials: J
authors.lastname: Yang
authors.forename: Fuxing
authors.initials: F
authors.lastname: Pei
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D001803:Blood Transfusion; D002681:China; D004322:Drainage / Q000379:methods*; D006801:Humans; D007902:Length of Stay; D011184:Postoperative Period; D016032:Randomized Controlled Trials as Topic