title: Acquired double pylorus: Clinical and endoscopic characteristics and four-year follow-up observations.
abstract: Double pylorus (DP), or duplication of the pylorus, is an uncommon condition that can be either congenital or acquired. Acquired DP (ADP) occurs when a peptic ulcer erodes and creates a fistula between the duodenal bulb and the distal stomach. The clinical features and endoscopic characteristics of four patients with ADP were reviewed and compared with previously reported cases. An accessory channel connects the lesser curvature of the prepyloric antrum with the duodenal bulb, and in all cases, a peptic ulcer was located in or immediately adjacent to the accessory channel. In one of the patients, the bridge between the double-channel pylorus disappeared, resulting in a single large opening and duodenal kissing ulcer after two years and three months. Finally, nonsteroidal anti-inflammatory drugs, Helicobacter pylori and other risk factors associated with ADP are assessed.
authors.affiliation: Jing-Jing Lei, Li Zhou, Qi Liu, Department of Gastroenterology, the Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang 550014, Guizhou Province, China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Lei
authors.affiliation: Jing-Jing Lei, Li Zhou, Qi Liu, Department of Gastroenterology, the Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang 550014, Guizhou Province, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhou
authors.affiliation: Jing-Jing Lei, Li Zhou, Qi Liu, Department of Gastroenterology, the Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang 550014, Guizhou Province, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Jing-Jing Lei, Li Zhou, Qi Liu, Department of Gastroenterology, the Affiliated Baiyun Hospital of Guizhou Medical University, Guiyang 550014, Guizhou Province, China.
authors.forename: Chun-Fang
authors.initials: CF
authors.lastname: Xu
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D004378:Duodenal Diseases / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D016145:Endoscopy, Digestive System; D005260:Female; D005747:Gastric Fistula / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D006801:Humans; D007412:Intestinal Fistula / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D010438:Peptic Ulcer Hemorrhage / Q000209:etiology; D011237:Predictive Value of Tests; D054328:Proton Pump Inhibitors / Q000627:therapeutic use; D011708:Pylorus / Q000000981:diagnostic imaging; D012307:Risk Factors; D013276:Stomach Ulcer / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000897:Anti-Ulcer Agents; D054328:Proton Pump Inhibitors
keywords: Acquired double pylorus; Gastrointestinal hemorrhage; Helicobacter pylori; Nonsteroidal anti-inflammatory drugs; Peptic ulcer