title: [Efficacy of thromboelastography to monitor the clinical massive transfusion in scoliosis: a randomized controlled trial].
abstract: OBJECTIVE
  To systematically assess the benefits and harms of a thromboela-stogram (TEG) guided transfusion strategy with severe bleeding.
  
  
  METHODS
  In this prospective study, 60 patients scheduled for scoliosis were included in the Fourth Affiliated Hospital, Xinjiang Medical University, from May 2014 to February 2014.Patients were allocated into either an TEG group or a standard management group.
  
  
  RESULTS
  There was no significant difference in age, weight, height and operation time between the two groups (P>0.05). There were significant differences in red blood cell concentration((4.5±1.5)units and(7.1±1.2)units)(t=4.343, P=0.001), platelet((2.5±1.3)units and (4.2±0.6)units)(t=4.554, P=0.002), fresh frozen plasma((234±46)ml and(514±41)ml)(t=3.723, P=0.004), fibrinogen((2.4±0.6)g and (4.6±0.7)g)(t=3.451, P=0.006) between the TEG group and the standard management group.The two groups in intraoperative blood loss((1 023±103)ml and (1 314±116)ml)(t=2.260, P=0.120), incidence of rebleeding after operation(3.1% and 3.6%)(χ(2)=0.340, P=0.450), hospitalization time((18±4)d and (16±6)d)(t=2.140, P=0.160) had no statistically significant differences.
  
  
  CONCLUSIONS
  Application of a TEG guided transfusion strategy seems to reduce the amount of bleeding during correction operation of scoliosis.
authors.affiliation: Department of Anesthesiology, Fourth Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, China.
authors.forename: Xinghua
authors.initials: X
authors.lastname: Cao
authors.forename: Xiaoting
authors.initials: X
authors.lastname: Zhang
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
mesh_terms: D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D006801:Humans; D008991:Monitoring, Physiologic; D011446:Prospective Studies; D012600:Scoliosis / Q000601:surgery*; D013916:Thrombelastography