title: Clinical application of FDG-PET/CT in metastatic infections.
abstract: FDG-PET/CT has proven its clinical value and cost-effectiveness in diagnosing metastatic infections in patients with Gram-positive bacteremia. In identification of metastatic foci, FDG-PET/CT is useful as a screening method when localizing symptoms are absent because it provides whole-body coverage. FDG-PET/CT detects early metabolic activity rather than the late anatomical changes as visualized by computed tomography and magnetic resonance imaging. FDG-PET/CT allows more precise localization of infection within a shorter time span between injection and diagnosis as compared to conventional nuclear imaging. This review focuses on the clinical application of imaging of metastatic infectious diseases, with an emphasis on FDG-PET/CT putting it in perspective with other imaging modalities.
authors.affiliation: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands - ilsekouijzer@gmail.com.
authors.forename: Ilse J
authors.initials: IJ
authors.lastname: Kouijzer
authors.affiliation: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.|Sint Maartenskliniek, Nijmegen, The Netherlands.
authors.forename: Fidel J
authors.initials: FJ
authors.lastname: Vos
authors.affiliation: Department of Internal Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Chantal P
authors.initials: CP
authors.lastname: Bleeker-Rovers
authors.affiliation: Department of Radiology and Nuclear Medicine, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Wim J
authors.initials: WJ
authors.lastname: Oyen
mesh_terms: D019788:Fluorodeoxyglucose F18; D016908:Gram-Positive Bacterial Infections / Q000000981:diagnostic imaging*; D006801:Humans; D000072078:Positron Emission Tomography Computed Tomography; D051598:Whole Body Imaging
chemical_list: D019788:Fluorodeoxyglucose F18