title: Impact of a personal CYP2D6 testing workshop on physician assistant student attitudes toward pharmacogenetics.
abstract: OBJECTIVE
  We assessed the impact of personal CYP2D6 testing on physician assistant student competency in, and attitudes toward, pharmacogenetics (PGx).
  
  
  METHODS
  Buccal samples were genotyped for CYP2D6 polymorphisms. Results were discussed during a 3-h PGx workshop. PGx knowledge was assessed by pre- and post-tests. Focus groups assessed the impact of the workshop on attitudes toward the clinical utility of PGx.
  
  
  RESULTS
  Both student knowledge of PGx, and its perceived clinical utility, increased immediately following the workshop. However, exposure to PGx on clinical rotations following the workshop seemed to influence student attitudes toward PGx utility.
  
  
  CONCLUSIONS
  Personal CYP2D6 testing improves both knowledge and comfort with PGx. Continued exposure to PGx concepts is important for transfer of learning.
authors.affiliation: Department of Pharmacology & Physiology, The George Washington University School of Medicine & Health Sciences, Washington, DC 20037, USA.
authors.forename: Travis J
authors.initials: TJ
authors.lastname: O'Brien
authors.affiliation: Department of Physician Assistant Studies, The George Washington University School of Medicine & Health Sciences, Washington, DC 20037, USA.
authors.forename: Susan
authors.initials: S
authors.lastname: LeLacheur
authors.affiliation: Department of Physician Assistant Studies, The George Washington University School of Medicine & Health Sciences, Washington, DC 20037, USA.
authors.forename: Caitlin
authors.initials: C
authors.lastname: Ward
authors.affiliation: Department of Pharmacology & Physiology, The George Washington University School of Medicine & Health Sciences, Washington, DC 20037, USA.
authors.forename: Norman H
authors.initials: NH
authors.lastname: Lee
authors.affiliation: Department of Clinical Research & Leadership, The George Washington University School of Medicine & Health Sciences, Washington, DC 20037, USA.
authors.forename: Shawneequa
authors.initials: S
authors.lastname: Callier
authors.affiliation: Department of Pharmacogenomics, Bernard J Dunn School of Pharmacy, Shenandoah University, Ashburn, VA 22601, USA.
authors.forename: Arthur F
authors.initials: AF
authors.lastname: Harralson
mesh_terms: D002983:Clinical Competence; D019389:Cytochrome P-450 CYP2D6 / Q000235:genetics*; D005820:Genetic Testing; D006801:Humans; D010597:Pharmacogenetics / Q000193:education*; D010823:Physician Assistants / Q000193:education*; D013663:Teaching / Q000379:methods*
chemical_list: D019389:Cytochrome P-450 CYP2D6
keywords: CYP2D6; education; genetic testing; personal testing; pharmacogenetics; pharmacogenomics; pharmacology; physician assistant