title: Diagnosis and microecological characteristics of aerobic vaginitis in outpatients based on preformed enzymes.
abstract: OBJECTIVE
  Aerobic vaginitis (AV) is a recently proposed term for genital tract infection in women. The diagnosis of AV is mainly based on descriptive diagnostic criteria proposed by Donders and co-workers. The objective of this study is to report AV prevalence in southwest China using an objective assay kit based on preformed enzymes and also to determine its characteristics.
  
  
  METHODS
  A total of 1948 outpatients were enrolled and tested by a commercial diagnostic kit to investigate the AV prevalence and characteristics in southwestern China. The study mainly examined the vaginal ecosystem, age distribution, Lactobacillus amount, and changes in pH. Differences within groups were analyzed by Wilcoxon two-sample test.
  
  
  RESULTS
  The AV detection rate is 15.40%. The AV patients were usually seen in the sexually active age group of 20-30 years, followed by those in the age group of 30-40 years. The vaginal ecosystems of all the patients studied were absolutely abnormal, and diagnosed to have a combined infection [aerobic vaginitis (AV) + bacterial vaginitis (BV) 61.33%; 184/300]. Aerobic bacteria, especially Staphylococcus aureus and Escherichia coli, were predominantly found in the vaginal samples of these women.
  
  
  CONCLUSIONS
  AV is a common type of genital infection in southwestern China and is characterized by sexually active age and combined infection predominated by the AV and BV type.
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Zhi-Liang
authors.initials: ZL
authors.lastname: Wang
authors.affiliation: Department of Obstetrics and Gynecology, Ningde Hospital, Fujian Medical University, Dongqiao District, Ningde City, China.
authors.forename: Lan-Yong
authors.initials: LY
authors.lastname: Fu
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China. Electronic address: docxza@163.com.
authors.forename: Zheng-Ai
authors.initials: ZA
authors.lastname: Xiong
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Qin
authors.affiliation: Department of Endocrine and Breast Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Teng-Hua
authors.initials: TH
authors.lastname: Yu
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Yu-Tong
authors.initials: YT
authors.lastname: Wu
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Yuan-Yuan
authors.initials: YY
authors.lastname: Hua
authors.affiliation: Department of Obstetrics and Gynecology, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Yong-Hong
authors.initials: YH
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D001420:Bacteria, Aerobic / Q000201:enzymology / Q000302:isolation & purification*; D001424:Bacterial Infections / Q000150:complications / Q000175:diagnosis* / Q000201:enzymology; D002681:China / Q000453:epidemiology; D003030:Coagulase / Q000032:analysis*; D060085:Coinfection / Q000175:diagnosis / Q000201:enzymology; D004926:Escherichia coli / Q000201:enzymology / Q000302:isolation & purification; D005260:Female; D005966:Glucuronidase / Q000032:analysis*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D064307:Microbiota; D008875:Middle Aged; D015995:Prevalence; D011933:Reagent Kits, Diagnostic; D013211:Staphylococcus aureus / Q000201:enzymology / Q000302:isolation & purification; D014621:Vagina / Q000201:enzymology / Q000382:microbiology*; D014627:Vaginitis / Q000175:diagnosis* / Q000201:enzymology / Q000453:epidemiology*; D016585:Vaginosis, Bacterial / Q000175:diagnosis / Q000201:enzymology; D055815:Young Adult
chemical_list: D003030:Coagulase; D011933:Reagent Kits, Diagnostic; D005966:Glucuronidase
keywords: aerobic vaginitis; genital tract infections; mixed infection; vaginal microecological