title: Orbito-Masticatory Syndrome.
abstract: We describe 2 unique cases of visual symptoms occurring during mastication in patients with lateral orbital wall defects. A 57-year-old man reported intermittent double vision and oscillopsia after a right fronto-temporal-orbito-zygomatic craniotomy with osteotomy of the lesser wing of the sphenoid for a complex invasive pituitary adenoma. Proptosis of the right globe was present only during mastication. Computed tomography (CT) revealed a bony defect in the right lateral orbital wall. A 48-year-old man presented with transient diplopia and scotoma in the right eye elicited by chewing. CT and magnetic resonance imaging demonstrated a bilobed lesion connecting the temporal fossa to the orbit through a defect in the right lateral orbital wall. The regional neuroanatomy and pathophysiology as pertaining to these cases are discussed.
authors.affiliation: Department of Ophthalmology (PM, MTB, MED), Duke University Eye Center, Durham, North Carolina; Department of Neurology (MTB), Duke University School of Medicine, Durham, North Carolina; Department of Ophthalmology (EBP), Loyola University Chicago, Maywood, Illinois; Department of Ophthalmology & Visual Sciences (AYL, PS, HEM), University of Illinois at Chicago, Chicago, Illinois; Department of Pathology (AYL), University of Illinois at Chicago, Chicago, Illinois; Department of Neurosurgery (AA), University of Illinois at Chicago, Chicago, Illinois; Department of Neurology & Rehabilitation (HEM), University of Illinois at Chicago, Chicago, Illinois.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Mettu
authors.forename: M Tariq
authors.initials: MT
authors.lastname: Bhatti
authors.forename: Mays A
authors.initials: MA
authors.lastname: El-Dairi
authors.forename: Evan B
authors.initials: EB
authors.lastname: Price
authors.forename: Amy Y
authors.initials: AY
authors.lastname: Lin
authors.forename: Ali
authors.initials: A
authors.lastname: Alaraj
authors.forename: Pete
authors.initials: P
authors.lastname: Setabutr
authors.forename: Heather E
authors.initials: HE
authors.lastname: Moss
mesh_terms: D003399:Craniotomy / Q000009:adverse effects* / Q000379:methods; D004172:Diplopia / Q000175:diagnosis / Q000209:etiology*; D005094:Exophthalmos / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008409:Mastication; D008875:Middle Aged; D009915:Orbit; D011183:Postoperative Complications; D013100:Sphenoid Bone / Q000601:surgery; D014057:Tomography, X-Ray Computed