title: Malignant melanoma of the nasal septum, a rare tumor, occurring in a 54-year-old patient after hereditary retinoblastoma treatment.
abstract: The authors report a case of a malignant melanoma of the nasal cavity that is a rare tumor and very aggressive, constituting 1% of all melanomas. It appeared in a patient 54 years after he was treated for a hereditary retinoblastoma. Its symptoms are nonspecific, and often marked by epistaxis. Its diagnosis is histological, supported by immunohistochemistry. Its prognosis is often unfavorable, and characterized by the occurrence of metastases and recurrences. Because of the risk of secondary cancer that exists in any survivor of hereditary retinoblastoma, we must think of possible mucosal melanoma of the nasal sinus in these patients in cases of chronic epistaxis. The prognosis of this tumor depends on its early diagnosis and surgical treatment.
authors.affiliation: Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: Windinmanégdé Pierre
authors.initials: WP
authors.lastname: Djiguimdé
authors.affiliation: Ophthalmology Department, University Hospital of Bouaké, University Alassane Ouattara, Bouaké, Cote d'Ivoire.
authors.forename: Ibrahim Abib
authors.initials: IA
authors.lastname: Diomandé
authors.affiliation: Ophthalmology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Bonnin
authors.affiliation: Otorhinolaryngology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Saroul
authors.affiliation: Radiology Department, University Hospital of Yopougon, University Félix Houphouët Boigny, Abidjan, Côte d'Ivoire.
authors.forename: Abdoulaye
authors.initials: A
authors.lastname: Touré
authors.affiliation: Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Sanou
authors.affiliation: Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: Paté
authors.initials: P
authors.lastname: Sankara
authors.affiliation: Otorhinolaryngology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Russier
authors.affiliation: Otorhinolaryngology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Gilain
authors.affiliation: Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: Ahgbatouhabéba
authors.initials: A
authors.lastname: Ahnoux-Zabsonré
authors.affiliation: Ophthalmology Department, University Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso.
authors.forename: Nonfounikoun
authors.initials: N
authors.lastname: Meda
authors.affiliation: Ophthalmology Department, University Hospital Clermont-Ferrand, Clermont-Ferrand, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Bacin
keywords: epistaxis; hereditary cancer; immunohistochemistry; nasosinusal melanoma; retinoblastoma