title: Functional Quality-of-Life Outcomes Reported by Men Treated for Localized Prostate Cancer: A Systematic Literature Review.
abstract: OBJECTIVE
  To systematically evaluate the literature for functional quality-of-life (QOL) outcomes following treatment for localized prostate cancer.  .
  
  
  METHODS
  The MEDLINE®, CINAHL®, EMBASE, British Nursing Index, PsycINFO®, and Web of Science™ databases were searched using key words and synonyms for localized prostate cancer treatments. .
  
  
  METHODS
  Of the 2,191 articles screened for relevance and quality, 24 articles were reviewed. Extracted data were tabulated by treatment type and sorted by dysfunction using a data-driven approach. .
  
  
  RESULTS
  All treatments caused sexual dysfunction and urinary side effects. Radiation therapy caused bowel dysfunction, which could be long-term or resolved within a few years. Sexual function could take years to return. Urinary incontinence resolved within two years of surgery but worsened following radiation therapy. Fatigue was worse during treatment with adjuvant androgen-deprivation therapy, and some men experienced post-treatment fatigue for several years.  .
  
  
  CONCLUSIONS
  This review identified that QOL outcomes reported by men following different treatments for localized prostate cancer are mostly recorded using standardized health-related QOL outcome measures. Such outcome measures collect data about body system functions but limit understanding of men's QOL following treatment for prostate cancer. Holistic outcome measures are needed to capture data about men's QOL for several years following the completion of treatment for localized prostate cancer. .
  
  
  CONCLUSIONS
  Nurses need to work with men to facilitate information sharing, identify supportive care needs, and promote self-efficacy, and they should make referrals to specialist services, as appropriate.
authors.affiliation: University College Hospital in London.
authors.forename: Hilary
authors.initials: H
authors.lastname: Baker
authors.affiliation: Churchill Hospital in Oxford.
authors.forename: Sandie
authors.initials: S
authors.lastname: Wellman
authors.affiliation: Oxford Brookes University in Oxford.
authors.forename: Verna
authors.initials: V
authors.lastname: Lavender
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006801:Humans; D008297:Male; D008875:Middle Aged; D011468:Prostatectomy / Q000009:adverse effects*; D011471:Prostatic Neoplasms / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D011788:Quality of Life / Q000523:psychology*; D012735:Sexual Dysfunction, Physiological / Q000209:etiology / Q000523:psychology*; D006113:United Kingdom; D014549:Urinary Incontinence / Q000209:etiology / Q000523:psychology*
keywords: EBRT; androgen deprivation; brachytherapy; cancer; prostate; prostatectomy