title: [UPLC/Q-TOF MS-Based Metabolomics Analysis of Chemical uiterences in Different Polygala tenuifolia Varieties].
abstract: OBJECTIVE
  The chemical differences of Polygala tenuifolia varieties-JinYuan 1 (JY1), FenYuan 2 (FY2) and traditional FenYang (FY) were studied, in order to provide reference for the breeding of Polygala tenuifolia.
  
  
  METHODS
  The samples of JY1, FY2 and FY were subjected to ultra-high performance liquid chromatography (UPLC) quadrupole time-of-flight mass spectrometry (Q-TOF MS) analysis. The obtained data were analyzed using Principal Component Analysis (PCA) and other statistical analysis methods, and differential metabolites were further figured out.
  
  
  RESULTS
  Compared with FY,sucrose esters (such as sibiricoses A5 and tenuifoliside B) and oligosaccharides (such as tenuifoliose K) in JY1 and FY2 contributed more to the separation of Polygala tenuifolia varieties in the PCA score plot. Compared with JYl, The sugar esters (such as tenuifoliside B and tenuifoliside A) and oligosaccharides( such as tenuifoliose A) in the FY2 also contributed more to the separation of Polygala tenuifolia varieties in the PCA score plot. In addition, the relative contents of sibiricaxanthone A,3,6'-disinapoly sucrose and senegin III showed significant differences among FY, JY1 and FY2.
  
  
  CONCLUSIONS
  As new Polygala tenuifolia varieties, JY1 and FY2 had certain differences and respective advantages on the chemical composition compared with FY,which could provide data support for the directional breeding of Polygala tenuifolia based on the contents of some active compounds.
authors.forename: Lu
authors.initials: L
authors.lastname: Bai
authors.forename: Xiao-shuang
authors.initials: XS
authors.lastname: Xu
authors.forename: Fu-sheng
authors.initials: FS
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Peng
authors.forename: Zu-ping
authors.initials: ZP
authors.lastname: Zeng
authors.forename: Hong-ling
authors.initials: HL
authors.lastname: Tian
authors.forename: Xue-mei
authors.initials: XM
authors.lastname: Qin
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004952:Esters / Q000737:chemistry; D013058:Mass Spectrometry; D055432:Metabolomics; D009844:Oligosaccharides / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry* / Q000145:classification; D031801:Polygala / Q000737:chemistry* / Q000145:classification; D025341:Principal Component Analysis
chemical_list: D004952:Esters; D009844:Oligosaccharides