title: [Cheek blood sampling of mice].
abstract: OBJECTIVE
  To explore the method of cheek blood sampling in mice in continuous blood test.
  
  
  METHODS
  Cheek blood sampling was carried out in 10 9-week-old mice once every 2-3 days. The volumes of blood samples were recorded. Reactions of the mice were observed.
  
  
  RESULTS
  Cheek blood sampling collected 0.3-0.6 ml of blood every time, and did not affect the normal activities of the mice. The blood sampling could be repeated every 2-3 days.
  
  
  CONCLUSIONS
  Cheek blood sampling has several advantages including being capable to draw adequate blood, simple and easy to operate, well tolerated, and ethical in treating laboratory animals.
authors.affiliation: State Key Laboratory of Experimental Hematology, Institute of Hematology and Blood Diseases Hospital, Chinese Academy Medical Sciences and Peking Union Medical College, Tianjin 300020, China.
authors.forename: Shuaishuai
authors.initials: S
authors.lastname: Zhang
authors.forename: Tianshou
authors.initials: T
authors.lastname: Li
authors.forename: Meirong
authors.initials: M
authors.lastname: Zang
authors.forename: Lugui
authors.initials: L
authors.lastname: Qiu
mesh_terms: D000818:Animals; D001800:Blood Specimen Collection; D002610:Cheek; D051379:Mice