title: Lupus as a paraneoplastic manifestation of cholangiocarcinoma.
abstract: Tumors originating in the digestive system, like those in other areas, whether solid or otherwise, may present with extradigestive manifestations in the setting of a paraneoplastic syndrome. Systemic lupus erythematosus (SLE) is an autoimmune condition most commonly involving women of childbearing age. On occasion it represents a paraneoplastic manifestation heralding a primary tumor. Cancer suspicion is therefore a key element for newly diagnosed SLE cases with nonstandard epidemiology even in the absence of suggestive symptoms, and digestive tumors should be included in the differential diagnosis.
authors.affiliation: UGC Aparato Digestivo, Hospital Universitario Virgen de la Victoria, España.
authors.forename: Yolanda
authors.initials: Y
authors.lastname: González Amores
authors.affiliation: UGC Aparato Digestivo, Hospital Don Benito.
authors.forename: Sofía
authors.initials: S
authors.lastname: Hernando Rebollar
authors.affiliation: Hospital Universitario Virgen de la Victoria.
authors.forename: Aida
authors.initials: A
authors.lastname: Casado Bernabeu
mesh_terms: D000368:Aged; D001650:Bile Duct Neoplasms / Q000150:complications* / Q000601:surgery; D018281:Cholangiocarcinoma / Q000150:complications* / Q000601:surgery; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000209:etiology*; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications* / Q000601:surgery; D010257:Paraneoplastic Syndromes / Q000150:complications*