title: 3D Printed Anatomical Nerve Regeneration Pathways.
abstract: An imaging-coupled 3D printing methodology for the design, optimization, and fabrication of a customized nerve repair technology for complex injuries is presented.The custom scaffolds are deterministically fabricated via a microextrusion printing principle which enables the simultaneous incorporation of anatomical geometries, biomimetic physical cues, and spatially controlled biochemical gradients in a one-pot 3D manufacturing approach.
authors.affiliation: Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States, Department of Industrial and Systems Engineering, Virginia Tech, Blacksburg, Virginia 24061, United States.
authors.forename: Blake N
authors.initials: BN
authors.lastname: Johnson
authors.affiliation: Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Karen Z
authors.initials: KZ
authors.lastname: Lancaster
authors.affiliation: Department of Orthopedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
authors.forename: Gehua
authors.initials: G
authors.lastname: Zhen
authors.affiliation: Department of Neurosurgery, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States.
authors.forename: Junyun
authors.initials: J
authors.lastname: He
authors.affiliation: Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Maneesh K
authors.initials: MK
authors.lastname: Gupta
authors.affiliation: Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Yong Lin
authors.initials: YL
authors.lastname: Kong
authors.affiliation: Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Esteban A
authors.initials: EA
authors.lastname: Engel
authors.affiliation: Department of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD 21205, United States.
authors.forename: Kellin D
authors.initials: KD
authors.lastname: Krick
authors.affiliation: Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Alex
authors.initials: A
authors.lastname: Ju
authors.affiliation: Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Fanben
authors.initials: F
authors.lastname: Meng
authors.affiliation: Department of Molecular Biology and Princeton Neuroscience Institute, Princeton University, Princeton, New Jersey 08544, United States.
authors.forename: Lynn W
authors.initials: LW
authors.lastname: Enquist
authors.affiliation: Department of Neurosurgery, Orthopedics, University of Maryland School of Medicine, Baltimore, Maryland 21201, United States, Department of Biomedical Engineering, Anesthesiology and Critical Care Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, United States.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Jia
authors.affiliation: Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, New Jersey 08544, United States, Department of Mechanical Engineering, University of Minnesota, Minneapolis, Minnesota 55455, United States.
authors.forename: Michael C
authors.initials: MC
authors.lastname: McAlpine
keywords: 3D printing; 3D scanning; nerve regeneration; neural engineering; tissue engineering