title: Oxytocin: A Conditional Anorexigen whose Effects on Appetite Depend on the Physiological, Behavioural and Social Contexts.
abstract: Central oxytocin suppresses appetite. Neuronal activity and the release of oxytocin coincide with satiation, as well as with adverse events (e.g. hyperosmolality, toxicity or excessive stomach distension) that necessitate an immediate termination of eating behaviour. Oxytocin also decreases consumption driven by reward, especially as derived from ingesting carbohydrates and sweet tastants. This review summarises current knowledge of the role of oxytocin in food intake regulation and highlights a growing body of evidence showing that oxytocin is a conditional anorexigen [i.e. its effects on appetite differ significantly with respect to certain (patho)physiological, behavioural and social contexts].
authors.affiliation: Department of Biological Sciences, University of Waikato, Hamilton, New Zealand.
authors.forename: P K
authors.initials: PK
authors.lastname: Olszewski
authors.affiliation: Department of Biological Sciences, University of Waikato, Hamilton, New Zealand.
authors.forename: A
authors.initials: A
authors.lastname: Klockars
authors.affiliation: Department of Food Science and Nutrition, University of Minnesota, St Paul, MN, USA.
authors.forename: A S
authors.initials: AS
authors.lastname: Levine
mesh_terms: D000818:Animals; D000855:Anorexia / Q000139:chemically induced* / Q000523:psychology*; D001066:Appetite / Q000502:physiology*; D001069:Appetite Regulation / Q000502:physiology*; D006801:Humans; D010121:Oxytocin / Q000502:physiology*; D012931:Social Environment
chemical_list: D010121:Oxytocin
keywords: appetite; oxytocin; reward; satiety