title: Cell Therapy for Parkinson's Disease.
abstract: In Parkinson's disease (PD), dopamine neurons in the substantia nigra are degenerated and lost. Cell therapy for PD replaces the lost dopamine neurons by transplanting donor dopamine neural progenitor cells. Cell therapy for PD has been performed in the clinic since the 1980s and uses donor cells from the mesencephalon of aborted embryos. Regenerative medicine for PD using induced pluripotent stem (iPS) cell technology is drawing attention, because it offers a limitless and more advantageous source of donor cells than aborted embryos.
authors.affiliation: Department of Clinical Application, Center for iPS Cell Research and Application, Kyoto University.
authors.forename: Asuka
authors.initials: A
authors.lastname: Morizane
authors.forename: Jun
authors.initials: J
authors.lastname: Takahashi
mesh_terms: D000818:Animals; D064987:Cell- and Tissue-Based Therapy; D004298:Dopamine / Q000378:metabolism; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D008636:Mesencephalon / Q000378:metabolism; D010300:Parkinson Disease / Q000628:therapy*
chemical_list: D004298:Dopamine