title: Interventional Molecular Imaging.
abstract: Although molecular imaging has had a dramatic impact on diagnostic imaging, it has only recently begun to be integrated into interventional procedures. Its significant impact is attributed to its ability to provide noninvasive, physiologic information that supplements conventional morphologic imaging. The four major interventional opportunities for molecular imaging are, first, to provide guidance to localize a target; second, to provide tissue analysis to confirm that the target has been reached; third, to provide in-room, posttherapy assessment; and fourth, to deliver targeted therapeutics. With improved understanding and application of(18)F-FDG, as well as the addition of new molecular probes beyond(18)F-FDG, the future holds significant promise for the expansion of molecular imaging into the realm of interventional procedures.
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and solomons@mskcc.org.
authors.forename: Stephen B
authors.initials: SB
authors.lastname: Solomon
authors.affiliation: Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York; and Department of Radiology, Pellegrin Hospital, Bordeaux, France.
authors.forename: Francois
authors.initials: F
authors.lastname: Cornelis
mesh_terms: D000818:Animals; D016503:Drug Delivery Systems; D006801:Humans; D057054:Molecular Imaging / Q000379:methods*; D009369:Neoplasms / Q000175:diagnosis*; D009683:Nuclear Medicine / Q000379:methods* / Q000639:trends; D049268:Positron-Emission Tomography; D019275:Radiopharmaceuticals; D014055:Tomography, Emission-Computed / Q000379:methods* / Q000639:trends
chemical_list: D019275:Radiopharmaceuticals
keywords: PET/CT; ablation; biopsy; cancer; fluorescence imaging; interventional oncology; interventional radiology; molecular imaging