title: Papillomavirus in yaks: the isolates of bovine papillomavirus type 1 have a high possibility of belonging to a novel type.
abstract: Although papillomaviruses (PVs) have been widely reported in vertebrates, there have been only a few PV reports in yaks (Bos grunniens). In 2012, Bam et al. reported bovine papillomavirus type 1 (BPV-1) and BPV-2 associated with cutaneous papillomatosis in yaks, which provided genomic and pathology information for yak PVs. However, nucleotide identity and phylogenic analyses revealed that there are two isolates with a high possibility of belonging to a novel type that is not BPV-1. The argument was thought to be caused by type-specific primers. Our analysis showed that BPV-1 type-specific primers can detect not only BPV-1 but also other PVs. It suggests that identification results using type-specific primers should be confirmed with more robust methods in molecular epidemiological studies.
authors.affiliation: Center for Animal Disease Control, University of Miyazaki, 1-1 Gakuen Kibanadai Nishi, Miyazaki 889-2192, Japan.
authors.forename: Jianbao
authors.initials: J
authors.lastname: Dong
authors.forename: Wei
authors.initials: W
authors.lastname: Zhu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Haga
mesh_terms: D000818:Animals; D052688:Bovine papillomavirus 1 / Q000235:genetics / Q000302:isolation & purification; D002417:Cattle / Q000821:virology*; D027383:Papillomaviridae / Q000235:genetics / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny