title: Getting a Grip on Microtubules.
abstract: Posttranslational modifications control microtubule behavior, yet assigning roles to particular signals was hampered by lack of defined in vitro systems. In this issue of Cell, Valenstein and Roll-Mecak establish a biochemical platform to interrogate consequences of microtubule polyglutamylation, thereby providing important insights into the specificity and quantitative nature of cellular information transfer.
authors.affiliation: Cytokinetics, 280 East Grand Avenue, South San Francisco, CA 94080, USA.
authors.forename: Julia
authors.initials: J
authors.lastname: Schaletzky
authors.affiliation: Howard Hughes Medical Institute, Berkeley, CA 94720, USA; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA. Electronic address: mrape@berkeley.edu.
authors.forename: Michael
authors.initials: M
authors.lastname: Rape
mesh_terms: D000251:Adenosine Triphosphatases / Q000378:metabolism*; D006801:Humans; D008870:Microtubules / Q000378:metabolism*; D011499:Protein Processing, Post-Translational; D015419:Spastic Paraplegia, Hereditary / Q000378:metabolism*; D014404:Tubulin / Q000378:metabolism*
chemical_list: D014404:Tubulin; D000251:Adenosine Triphosphatases