title: [Intramedullary hemangioblastomas].
abstract: OBJECTIVE
  Intramedullary hemangioblastomas are rare lesions representing 1 to 5% of spinal tumors. The aim of this study was to review our experience with the surgical management of intramedullary hemangioblastomas.
  
  
  METHODS
  We performed a retrospective analysis of all the patients with intramedullary hemangioblastomas operated on between 1993 and 2011 in our department. All the patients were screened for Von Hippel Lindau disease. The minimum follow-up was 3 years. The clinical presentation, radiological findings, surgical procedure and outcomes were recorded and analyzed.
  
  
  RESULTS
  Our consecutive series included 59 patients with a total of 65 tumors. The mean age at diagnosis was 38 years. Forty-two patients (72.5%) had Von Hippel Lindau disease. The main symptom was pain (58% of cases). The most common location was cervical spinal cord. The average size was 15mm. The resection was complete in 95% cases resulting in clinical improvement in 12% cases, stability in more than 86% of cases and deterioration in less than 2% cases.
  
  
  CONCLUSIONS
  All patients with intramedullary hemangioblastoma should have a screening for the Von Hippel Lindau disease and if the diagnosis is correct, close monitoring should be initiated. Surgical removal is strongly advised in cases of neurological deficits or radiological progression of the tumour.
authors.affiliation: Service de neurochirurgie, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France; Centre expert national cancers rares PREDIR, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre, France.
authors.forename: P
authors.initials: P
authors.lastname: David
authors.affiliation: Service de neurochirurgie, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France. Electronic address: mahmoud.messerer@bct.aphp.fr.
authors.forename: M
authors.initials: M
authors.lastname: Messerer
authors.affiliation: Service de neurochirurgie, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France.
authors.forename: N
authors.initials: N
authors.lastname: Aghakhani
authors.affiliation: Service de neuroradiologie, hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France.
authors.forename: F
authors.initials: F
authors.lastname: Benoudiba
authors.affiliation: Laboratoire d'anatomie pathologique, hôpital Bicêtre, AP-HP, Le Kremlin-Bicêtre, France.
authors.forename: C
authors.initials: C
authors.lastname: Adam
authors.affiliation: Centre expert national cancers rares PREDIR, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre, France.
authors.forename: S
authors.initials: S
authors.lastname: Richard
authors.affiliation: Service de neurochirurgie, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre cedex, France; Centre expert national cancers rares PREDIR, hôpital Bicêtre, AP-HP, 78, rue du General-Leclerc, 94275 Le Kremlin-Bicêtre, France.
authors.forename: F
authors.initials: F
authors.lastname: Parker
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D018325:Hemangioblastoma / Q000150:complications / Q000601:surgery*; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000601:surgery*; D006623:von Hippel-Lindau Disease / Q000209:etiology*
keywords: Hémangiobastomes intramédullaires; Intramedullary hemangioblastomas; Maladie de Von Hippel Lindau; Spinal cord tumors; Tumeurs de la moelle épinière; Von Hippel Lindau