title: Optical coherence tomography plaque characterization in a patient with ST segment elevation myocardial infarction after cocaine intake.
abstract: A 28-year old man presented to the Emergency Department with malaise after cocaine intake. After arrival he developed retrosternal chest pain and the electrocardiogram showed ST segment elevations in V1-V2 and ST segment depressions in V5-V6. An acute coronary angiogram revealed a focal non-occlusive lesion with thrombus in the left anterior descending artery. Supplementary optical coherence tomography (OCT) detected plaque erosion with adherent thrombus to be the responsible underlying pathophysiological mechanism. The patient received an effective antithrombotic regimen. Repeat angiogram with additional OCT one month later documented thrombus resolution and complete restoration of the previously eroded coronary vascular surface area.
authors.affiliation: Emergency Department, Kolding Hospital, Skovvangen 2-8, DK-6000 Kolding, Denmark. Electronic address: morten.steen.hansen2@rsyd.dk.
authors.forename: Morten Steen Svarer
authors.initials: MS
authors.lastname: Hansen
authors.affiliation: Department of Cardiology, Odense University Hospital, Sdr. Boulevard 29, DK-5000 Odense, Denmark.
authors.forename: Lisbeth
authors.initials: L
authors.lastname: Antonsen
authors.affiliation: Department of Cardiology, Odense University Hospital, Sdr. Boulevard 29, DK-5000 Odense, Denmark.
authors.forename: Lisette Okkels
authors.initials: LO
authors.lastname: Jensen
mesh_terms: D000328:Adult; D019970:Cocaine-Related Disorders / Q000150:complications*; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000139:chemically induced / Q000000981:diagnostic imaging*; D003328:Coronary Thrombosis / Q000139:chemically induced / Q000000981:diagnostic imaging*; D003331:Coronary Vessels / Q000000981:diagnostic imaging* / Q000187:drug effects; D004562:Electrocardiography; D006801:Humans; D008297:Male; D058226:Plaque, Atherosclerotic; D000072657:ST Elevation Myocardial Infarction / Q000139:chemically induced / Q000000981:diagnostic imaging*; D041623:Tomography, Optical Coherence
keywords: Cocaine; Myocardial infarction; Optical coherence tomography; Plaque erosion