title: Progress in the use of microemulsions for transdermal and dermal drug delivery.
abstract: Transdermal drug delivery continues to attract considerable interest in the scientific community. However, due to the hindrance provided by the stratum corneum, it is not possible to deliver most medications in therapeutically significant amounts. One of the ways of increasing the penetration of drugs across the skin is through the use of microemulsions (MEs). This review focuses on the role of MEs in enhancing topical and transdermal drug delivery.
authors.affiliation: a College of Pharmacy, Touro University , Mare Island-Vallejo, CA , USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Ita
mesh_terms: D000279:Administration, Cutaneous; D000818:Animals; D002986:Clinical Trials as Topic; D016503:Drug Delivery Systems / Q000379:methods; D004655:Emulsions / Q000737:chemistry* / Q000378:metabolism; D006801:Humans; D009821:Oils / Q000737:chemistry* / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000008:administration & dosage*; D012867:Skin / Q000378:metabolism*; D012869:Skin Absorption; D013501:Surface-Active Agents / Q000737:chemistry* / Q000378:metabolism
chemical_list: D004655:Emulsions; D009821:Oils; D004364:Pharmaceutical Preparations; D013501:Surface-Active Agents
keywords: Drug delivery; microemulsion; oil phase; skin; surfactant; transdermal