title: Left Adrenal Gland Analysis in Lung Cancer Patients Using the Endobronchial Ultrasound Scope: A Feasibility Trial.
abstract: BACKGROUND
  In lung cancer patients, the adrenal glands are predilection sites for distant metastases. Esophageal endoscopic ultrasound - fine-needle aspiration (EUS-FNA) is a minimally invasive and accurate method for left adrenal gland (LAG) analysis but requires a conventional gastrointestinal echoendoscope. Complete endobronchial and esophageal mediastinal nodal staging can be achieved by just a single endobronchial ultrasound (EBUS) scope, introducing it into the esophagus (EUS-B) following the endobronchial procedure. Whether the LAG can also be assessed with the EBUS scope is unknown.
  
  
  OBJECTIVE
  The aim of the study was to investigate the feasibility of identifying the LAG with the EBUS scope.
  
  
  METHODS
  We conducted a retrospective analysis of lung cancer patients who underwent EBUS and EUS-B for mediastinal staging and LAG assessment between January 2013 and May 2015.
  
  
  RESULTS
  A total of 143 patients with (suspected) lung cancer were investigated by the combination of EBUS and EUS-B. In 68 of the 80 patients (85%) in whom an attempt was made to identify the LAG, it was feasible to transgastrically detect the LAG with the EBUS scope. In 9 patients with endosonographic signs of malignant involvement, diagnostic transgastric FNAs were obtained in all. In the 12 patients (15%) in whom the LAG was not detected, the contact between the ultrasound transducer and the gastric wall was suboptimal - the length of the scope was not a limiting factor.
  
  
  CONCLUSIONS
  The EBUS scope allows identification of the LAG in the vast majority of lung cancer patients.
  
  
  CONCLUSIONS
  In patients with (suspected) lung cancer, in addition to complete hilar and mediastinal staging, LAG assessment using just a single EBUS scope also seems feasible. Prospective studies are indicated.
authors.affiliation: Department of Pulmonology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Laurence M M J
authors.initials: LM
authors.lastname: Crombag
authors.forename: Jouke T
authors.initials: JT
authors.lastname: Annema
mesh_terms: D000230:Adenocarcinoma / Q000473:pathology*; D000311:Adrenal Glands / Q000473:pathology*; D000368:Aged; D000369:Aged, 80 and over; D044963:Biopsy, Fine-Needle; D001999:Bronchoscopy / Q000379:methods*; D019160:Endosonography / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies