title: [Impact of long-term continuous positive airway pressure treatment for patients with obstructive sleep apnea syndrome].
abstract: OBJECTIVE
  To investigate the long-term efficacy of continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnea syndrome (OSAS).
  
  
  METHODS
  This case control study was performed among 154 patients with moderate or severe OSAS between September 2009 and September 2014. Patients were divided into treatment group (n=66, 53 patients with hypertension) and control group (n=88, 67 patients with hypertension). The long-term efficacy of CPAP treatment on clinical events and blood pressure was evaluated.
  
  
  RESULTS
  The combined incidence of death, myocardial infarction, coronary revascularization and stroke events was 1.5% (1/66) in treatment group and 11.4% (10/88) in control group (P<0.05). CPAP treatment also led to more significant reduction in systolic blood pressure ((12.24±18.06) mmHg(1 mmHg=0.133 kPa) to (4.24±16.63) mmHg, P<0.05) in the patients with hypertension in these two groups.
  
  
  CONCLUSIONS
  CPAP treatment could reduce the risk of cardiovascular and neurovascular events for patients with moderate or severe OSAS.
authors.affiliation: Hypertension Division, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Qi
authors.forename: Menggengtuya
authors.initials: M
authors.lastname: Cai
authors.forename: H M
authors.initials: HM
authors.lastname: Zhang
authors.forename: L R
authors.initials: LR
authors.lastname: Yang
authors.forename: F
authors.initials: F
authors.lastname: Qin
authors.forename: E P
authors.initials: EP
authors.lastname: Liang
authors.forename: X J
authors.initials: XJ
authors.lastname: Jiang
authors.forename: L
authors.initials: L
authors.lastname: Song
authors.forename: H Y
authors.initials: HY
authors.lastname: Wu
authors.forename: X L
authors.initials: XL
authors.lastname: Zhou
authors.forename: Y B
authors.initials: YB
authors.lastname: Zou
authors.forename: X J
authors.initials: XJ
authors.lastname: Gao
authors.forename: H Y
authors.initials: HY
authors.lastname: Qian
authors.forename: J
authors.initials: J
authors.lastname: Bian
mesh_terms: D001794:Blood Pressure; D016022:Case-Control Studies; D045422:Continuous Positive Airway Pressure; D006801:Humans; D006973:Hypertension; D015994:Incidence; D020181:Sleep Apnea, Obstructive