title: PI3K/AKT Pathway and Brain Malformations.
abstract: Investigators from Seattle Children's Research Institute, University of Washington, and collaborating institutions sought to evaluate 10 genes in the PI3K/AKT pathway as it relates epileptogenic brain malformations in patients with megalencephaly, hemimegalencephaly, and focal cortical dysplasia.
authors.affiliation: Department of Pathology and Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Furman University, Greenville, SC.
authors.forename: Gavin B
authors.initials: GB
authors.lastname: Rice
authors.affiliation: Department of Pathology and Laboratory Medicine, Ann & Robert H. Lurie Children's Hospital of Chicago, Chicago, IL; Department of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL.
authors.forename: Nitin R
authors.initials: NR
authors.lastname: Wadhwani
keywords: Cortical dysplasia; Megalencephaly; PI3K/AKT mutations