title: Infrastructure for Personalized Medicine at Partners HealthCare.
abstract: Partners HealthCare Personalized Medicine (PPM) is a center within the Partners HealthCare system (founded by Massachusetts General Hospital and Brigham and Women's Hospital) whose mission is to utilize genetics and genomics to improve the care of patients in a cost effective manner. PPM consists of five interconnected components: (1) Laboratory for Molecular Medicine (LMM), a CLIA laboratory performing genetic testing for patients world-wide; (2) Translational Genomics Core (TGC), a core laboratory providing genomic platforms for Partners investigators; (3) Partners Biobank, a biobank of samples (DNA, plasma and serum) for 50,000 Consented Partners patients; (4) Biobank Portal, an IT infrastructure and viewer to bring together genotypes, samples, phenotypes (validated diagnoses, radiology, and clinical chemistry) from the electronic medical record to Partners investigators. These components are united by (5) a common IT system that brings researchers, clinicians, and patients together for optimal research and patient care.
authors.affiliation: Partners Personalized Medicine, Partners HealthCare System, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA. Scott.weiss@channing.harvard.edu.
authors.forename: Scott T
authors.initials: ST
authors.lastname: Weiss
authors.affiliation: Partners Personalized Medicine, Partners HealthCare System, Boston, MA 02139, USA. msumbadashin@partners.org.
authors.forename: Meini Sumbada
authors.initials: MS
authors.lastname: Shin
keywords: Partners HealthCare; academic medical centers; biobank; bioinformatics; information technology infrastructure; laboratory testing; personalized medicine