title: (18)F-FDG PET imaging of granulomatosis with polyangiitis -Wegener's Syndrome.
abstract: OBJECTIVE
  Granulomatosis with polyangiitis (GPA), formerly called Wegener's syndrome, is a vasculitis associated with antineutrophil cytoplasmic antibody and may occur in all ages but mostly in order adults. The organs most frequently involved are the ear, nose and throat (rhinitis, sinusitus, oral ulcers, chondritis), the lungs (nodules, sometimes cavitating, infiltrates, hilar adenopathy) and the kidneys (glomerulonephritis). As patients typically present with constitutional symptoms, the diagnosis can be challenging. We report the findings on position emission tomography/computed tomography (PET/CT) with fluorine-18-fluorodeoxyglucose ((18)F-FDG) in a patient with a limited form of GPA.
  
  
  CONCLUSIONS
  None of the findings on PET are specific for GPA, but in a given clinical context, they may contribute to early diagnosis. They may guide biopsy taking, and may determine the extent of the disease. During and after treatment, PET can be used to monitor disease activity.
authors.affiliation: Department of Nuclear Medicine, Algemeen Ziekenhuis Sint-Jan Brugge-Oostende Ruddershove 10, B-8000 Brugge, Belgium. frank.degeeter@azsintjan.be.
authors.forename: Frank
authors.initials: F
authors.lastname: De Geeter
authors.forename: Pieterjan
authors.initials: P
authors.lastname: Gykiere
mesh_terms: D000328:Adult; D019788:Fluorodeoxyglucose F18; D014890:Granulomatosis with Polyangiitis / Q000175:diagnosis*; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008297:Male; D064847:Multimodal Imaging / Q000379:methods*; D049268:Positron-Emission Tomography / Q000379:methods*; D019275:Radiopharmaceuticals; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18