title: Locally advanced hypopharyngeal squamous cell carcinoma: single-institution outcomes in a cohort of patients curatively treated either with or without larynx preservation.
abstract: OBJECTIVE
  The present study was aimed at describing a single-institution experience in the curative treatment of patients diagnosed with locally advanced hypopharyngeal squamous cell carcinoma.
  
  
  METHODS
  Data concerning all patients treated for locally advanced hypopharyngeal squamous cell carcinoma between January 2006 and June 2012 were reviewed.
  
  
  RESULTS
  A total of 144 patients were included in the present study. The median follow-up period was 36.6 months. Median survival was 26 months, and 2-year and 5-year overall survival rates were, 51% and 30.5%, respectively. Median recurrence-free survival was 18 months and 2-year and 5-year recurrence-free survival rates were 42.8% and 28.5%, respectively.
  
  
  CONCLUSIONS
  The outcomes in the present series are in line with the literature.
authors.affiliation: MDs, Radiation Oncologists, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: Isabel
authors.initials: I
authors.lastname: Reis
authors.affiliation: MDs, Radiation Oncologists, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: Artur
authors.initials: A
authors.lastname: Aguiar
authors.affiliation: MDs, Radiation Oncology Residents, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: Cristiana
authors.initials: C
authors.lastname: Alzamora
authors.affiliation: MDs, Radiation Oncology Residents, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: Carolina
authors.initials: C
authors.lastname: Ferreira
authors.affiliation: MDs, Radiation Oncologists, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: Vera
authors.initials: V
authors.lastname: Castro
authors.affiliation: MDs, Radiation Oncologists, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: André
authors.initials: A
authors.lastname: Soares
authors.affiliation: MDs, Radiation Oncologists, Radiation Oncology Department, Instituto Português de Oncologia do Porto Francisco Gentil (IPO-Porto), Porto, Portugal.
authors.forename: Marisa
authors.initials: M
authors.lastname: Lobão
keywords: Hypopharynx; Outcomes; Radiotherapy; Surgery