title: Dissolution of a mineral trioxide aggregate sealer in endodontic solvents compared to conventional sealers.
abstract: The aim of this study is to evaluate the solubility of a Mineral Trioxide Aggregate sealer (MTA-Fillapex) compared with five other sealers, calcium hydroxide (Sealapex), resin (Realseal), zinc oxide-eugenol (Tubli-Seal), and two epoxy resins (AH-26 and AH-Plus), in chloroform and eucalyptoil in static and ultrasonic environments. Samples of each sealer were prepared (n = 180) and then divided into 12 groups that were immersed in solvents for 5 and 10 min in static and ultrasonic environments. The mean weight loss was determined, and the values were compared using Student's t-test, One-way ANOVA, and Tukey's HSD post-hoc test (p < 0.05). In chloroform, MTA-Fillapex, AH-26, and Sealapex displayed moderate solubility with no significant difference in dissolution (p = 0.125); however, their dissolution was significantly lower than that of AH-Plus (p < 0.001), which was almost fully dissolved after 10 minutes. Realseal was significantly less soluble than all sealers (p < 0.001). In eucalyptoil, MTA-Fillapex showed low solubility, as all of the sealers did, but Tubli-Seal was significantly more soluble than other sealers (p < 0.001). Using ultrasonic activation resulted in a significantly higher dissolution rate in chloroform for all sealers except MTA-Fillapex after 10 min (p = 0.226). In eucalyptoil, ultrasonic activation significantly increased the dissolution rate of all sealers except MTA-Fillapex after 5 and 10 min, Sealapex at 10 min, and AH-Plus at 5 min (p > 0.05). In conclusion, MTA-Fillapex was not sufficiently dissolved in either solvent. Ultrasonic activation had limited effectiveness on MTA-Fillapex dissolution, whereas it significantly increased the efficiency of solvents in dissolving a number of endodontic sealers.
authors.affiliation: Department of Conservative Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan.
authors.forename: Hanan
authors.initials: H
authors.lastname: Alzraikat
authors.affiliation: Department of Conservative Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan.
authors.forename: Nessrin Ahmad
authors.initials: NA
authors.lastname: Taha
authors.affiliation: Department of Conservative Dentistry, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan.
authors.forename: Layla
authors.initials: L
authors.lastname: Hassouneh
mesh_terms: D017607:Aluminum Compounds / Q000737:chemistry*; D000704:Analysis of Variance; D001729:Bismuth / Q000737:chemistry; D017610:Calcium Compounds / Q000737:chemistry*; D002126:Calcium Hydroxide / Q000737:chemistry; D002725:Chloroform / Q000737:chemistry*; D003511:Cyclohexanols / Q000737:chemistry*; D004338:Drug Combinations; D004853:Epoxy Resins / Q000737:chemistry; D000077591:Eucalyptol; D007101:Immersion; D008422:Materials Testing; D039821:Monoterpenes / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry*; D012016:Reference Values; D015203:Reproducibility of Results; D012387:Root Canal Filling Materials / Q000737:chemistry*; D012459:Salicylates / Q000737:chemistry; D017640:Silicates / Q000737:chemistry*; D012834:Silver / Q000737:chemistry; D012995:Solubility; D012997:Solvents / Q000737:chemistry*; D013997:Time Factors; D014025:Titanium / Q000737:chemistry; D000069453:Ultrasonic Waves; D015035:Zinc Oxide-Eugenol Cement / Q000737:chemistry
chemical_list: D017607:Aluminum Compounds; D017610:Calcium Compounds; D003511:Cyclohexanols; D004338:Drug Combinations; D004853:Epoxy Resins; D039821:Monoterpenes; D010087:Oxides; D012387:Root Canal Filling Materials; D012459:Salicylates; D017640:Silicates; D012997:Solvents; D015035:Zinc Oxide-Eugenol Cement; C534916:epoxy resin-based root canal sealer; C086631:mineral trioxide aggregate; C055601:Sealapex; D012834:Silver; C028044:epoxy resin AH-26; C048769:tubliseal; D002725:Chloroform; D014025:Titanium; D002126:Calcium Hydroxide; D000077591:Eucalyptol; D001729:Bismuth