title: Photochemical Synthesis of Shape-Controlled Nanostructured Gold on Zinc Oxide Nanorods as Photocatalytically Renewable Sensors.
abstract: Biosensors always suffer from passivation that prevents their reutilization. To address this issue, photocatalytically renewable sensors composed of semiconductor photocatalysts and sensing materials have emerged recently. In this work, we developed a robust and versatile method to construct different kinds of renewable biosensors consisting of ZnO nanorods and nanostructured Au. Via a facile and efficient photochemical reduction, various nanostructured Au was obtained successfully on ZnO nanorods. As-prepared sensors concurrently possess excellent sensing capability and desirable photocatalytic cleaning performance. Experimental results demonstrate that dendritic Au/ZnO composite has the strongest surface-enhanced Raman scattering (SERS) enhancement, and dense Au nanoparticles (NPs)/ZnO composite has the highest electrochemical activity, which was successfully used for electrochemical detection of NO release from cells. Furthermore, both of the SERS and electrochemical sensors can be regenerated efficiently for renewable applications via photodegrading adsorbed probe molecules and biomolecules. Our strategy provides an efficient and versatile method to construct various kinds of highly sensitive renewable sensors and might expand the application of the photocatalytically renewable sensor in the biosensing area.
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Jia-Quan
authors.initials: JQ
authors.lastname: Xu
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Huan-Huan
authors.initials: HH
authors.lastname: Duo
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Yu-Ge
authors.initials: YG
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Xin-Wei
authors.initials: XW
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Fang
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Yan-Ling
authors.initials: YL
authors.lastname: Liu
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Shen
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Ji-Ming
authors.initials: JM
authors.lastname: Hu
authors.affiliation: Key Laboratory of Analytical Chemistry for Biology and Medicine, Ministry of Education, College of Chemistry and Molecular Sciences, Wuhan University , Wuhan 430072, China.
authors.forename: Wei-Hua
authors.initials: WH
authors.lastname: Huang
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D002384:Catalysis; D002712:Chlorides / Q000737:chemistry; D017743:Equipment Reuse; D006046:Gold / Q000737:chemistry*; D017612:Gold Compounds / Q000737:chemistry; D053768:Metal Nanoparticles / Q000737:chemistry*; D043942:Nanotubes / Q000737:chemistry*; D010084:Oxidation-Reduction; D055668:Photochemical Processes; D013059:Spectrum Analysis, Raman; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D002712:Chlorides; D017612:Gold Compounds; D006046:Gold; C024568:gold tetrachloride, acid; D015034:Zinc Oxide