title: Psychosocial outcomes and interventions among cancer survivors diagnosed during adolescence and young adulthood (AYA): a systematic review.
abstract: A cancer diagnosis during adolescence or young adulthood (AYA; defined as ages 15-39) generates unique medical and psychosocial needs as developmental milestones are simultaneously impacted. Past research highlights that AYAs' experiences and psychosocial outcomes are different, and more research and attention is needed. We aimed to identify and synthesize literature regarding psychosocial outcomes, unique needs, and existing psychosocial interventions pertaining to individuals diagnosed with cancer exclusively during AYA, and to highlight areas for future research.
  
  
  
  A systematic literature search was conducted using MEDLINE (via PubMed), EMBASE, Cochrane, Web of Science, and PsycINFO (via OVID). Grey literature was searched using key term variations and combinations. Overall, 15,301 records were assessed by two independent reviewers, with 38 studies meeting inclusion criteria.
  
  
  
  Data synthesis of the 38 articles was organized by four main themes based on quality of life and survivorship: physical well-being (7 studies), psychological well-being (8 studies), social well-being (9 studies), and survivorship care (14 studies). The paucity of studies for such broad inclusion criteria highlights that this population is often combined or subsumed under other age groups, missing needs unique to these AYAs.
  
  
  
  AYA cancer survivors' experiences are nuanced, with interacting variables contributing to post-treatment outcomes. AYAs require age-appropriate and flexible care, informational needs and treatment-related education that foster autonomy for long-term survivorship, as well as improved follow-up care and psychological outcomes.
  
  
  
  By incorporating these findings into practice, the informational and unmet needs of AYAs can be addressed effectively. Education and programming is lacking specific and general subject matter specific to AYAs, incorporating ranging needs at different treatment stages.
authors.affiliation: Columbia University Medical Center, New York, NY, USA.
authors.forename: Marie
authors.initials: M
authors.lastname: Barnett
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.|St. John's University Department of Psychology, Queens, NY, USA.
authors.forename: Glynnis
authors.initials: G
authors.lastname: McDonnell
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.
authors.forename: Antonio
authors.initials: A
authors.lastname: DeRosa
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.|Association for Behavioral and Cognitive Therapies, New York, NY, USA.
authors.forename: Tammy
authors.initials: T
authors.lastname: Schuler
authors.affiliation: The Notre Dame Laboratory for Psycho-oncology Research, Notre Dame, IN, USA.
authors.forename: Errol
authors.initials: E
authors.lastname: Philip
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.
authors.forename: Lisa
authors.initials: L
authors.lastname: Peterson
authors.affiliation: Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA.
authors.forename: Kaitlin
authors.initials: K
authors.lastname: Touza
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.
authors.forename: Sabrina
authors.initials: S
authors.lastname: Jhanwar
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA.
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Atkinson
authors.affiliation: Department of Psychiatry & Behavioral Sciences, Memorial Sloan Kettering Cancer Center, 641 Lexington Ave., 7th Floor, New York, NY, 10022, USA. fordj@mskcc.org.
authors.forename: Jennifer S
authors.initials: JS
authors.lastname: Ford
mesh_terms: D000223:Adaptation, Psychological; D000293:Adolescent; D006801:Humans; D009369:Neoplasms / Q000523:psychology* / Q000628:therapy*; D011788:Quality of Life; D013315:Stress, Psychological; D017741:Survivors / Q000523:psychology*; D055815:Young Adult
keywords: Adolescent; Cancer survivorship; Literature review; Neoplasms; Young adult