title: blastjs: a BLAST+ wrapper for Node.js.
abstract: BACKGROUND
  To cope with the ever-increasing amount of sequence data generated in the field of genomics, the demand for efficient and fast database searches that drive functional and structural annotation in both large- and small-scale genome projects is on the rise. The tools of the BLAST+ suite are the most widely employed bioinformatic method for these database searches. Recent trends in bioinformatics application development show an increasing number of JavaScript apps that are based on modern frameworks such as Node.js. Until now, there is no way of using database searches with the BLAST+ suite from a Node.js codebase.
  
  
  RESULTS
  We developed blastjs, a Node.js library that wraps the search tools of the BLAST+ suite and thus allows to easily add significant functionality to any Node.js-based application.
  
  
  CONCLUSIONS
  blastjs is a library that allows the incorporation of BLAST+ functionality into bioinformatics applications based on JavaScript and Node.js. The library was designed to be as user-friendly as possible and therefore requires only a minimal amount of code in the client application. The library is freely available under the MIT license at https://github.com/teammaclean/blastjs.
authors.affiliation: Bioinformatics Group, The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK. martin.page@tsl.ac.uk.
authors.forename: Martin
authors.initials: M
authors.lastname: Page
authors.affiliation: Bioinformatics Group, The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK. dan.maclean@tsl.ac.uk.
authors.forename: Dan
authors.initials: D
authors.lastname: MacLean
authors.affiliation: Bioinformatics Group, The Sainsbury Laboratory, Norwich Research Park, Norwich, NR4 7UH, UK. christian.schudoma@tsl.ac.uk.|Triticeae Genomics Group, The Genome Analysis Centre, Norwich Research Park, Norwich, NR4 7UH, UK. christian.schudoma@tsl.ac.uk.
authors.forename: Christian
authors.initials: C
authors.lastname: Schudoma
mesh_terms: D000465:Algorithms; D019295:Computational Biology / Q000379:methods*; D030541:Databases, Genetic; D006801:Humans; D016415:Sequence Alignment / Q000379:methods*; D017422:Sequence Analysis, DNA; D020539:Sequence Analysis, Protein; D017423:Sequence Analysis, RNA; D012984:Software