title: Influence of intrapulmonary percussive ventilation in upright position on gastro-oesophageal reflux in infants.
abstract: To determine the influence of physiotherapy using intrapulmonary percussive ventilation on gastro-oesophageal reflux (GOR) in infants <1 year.
  
  
  
  In this controlled trial with intra-subject design, children were studied using multichannel intraluminal impedance pH (pH-MII) monitoring over 24 hr, during which they received one 20-min session of intrapulmonary percussive ventilation in upright position (IPVR), 2 hr after their latest feeding. Two hours after each feeding, the number of reflux episodes (RE) over a 20-min period was registered for each infant and a mean per 20 min was calculated in order to obtain a baseline value. The number of RE during IPVRintervention was compared to baseline.
  
  
  
  Fifty infants with a median age of 133 days were recruited of whom 21 were diagnosed with pathological GOR. During IPVR, the incidence of RE in the entire group was significantly lower compared to baseline; median (inter-quartile range [IQR]) 0 (0-1) versus 0.71 (0-1.33) RE, respectively, P = 0.003. The subgroup with abnormal GOR showed also a significant decrease of RE during IPVR; median (IQR) 0 (0-1) versus 1.17 (0.55-2.16) RE, respectively, P = 0.03. No difference was detected in the group with normal reflux; median (IQR) 0.6 (0-1) compared to 0 (0-1) RE, respectively, P = 0.34.
  
  
  
  IPVRdoes not induce, nor aggravate GOR in infants without and with pathological GOR, respectively, but on the contrary decreases the number of RE in patients with pathological reflux. Pediatr Pulmonol. 2016;51:1065-1071. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium. filip.vanginderdeuren@telenet.be.|Department of Physiotherapy, UZ Brussel, Brussels, Belgium. filip.vanginderdeuren@telenet.be.
authors.forename: F
authors.initials: F
authors.lastname: Van Ginderdeuren
authors.affiliation: Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: E
authors.initials: E
authors.lastname: Kerckhofs
authors.affiliation: Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Deneyer
authors.affiliation: Department of Physiotherapy, UZ Brussel, Brussels, Belgium.
authors.forename: S
authors.initials: S
authors.lastname: Vanlaethem
authors.affiliation: Department of Public Health, Biostatistics and Medical Informatics, Information Research Group, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: R
authors.initials: R
authors.lastname: Buyl
authors.affiliation: Department of Pediatrics, UZ Brussel, Vrije Universiteit Brussel, Brussels, Belgium.
authors.forename: Y
authors.initials: Y
authors.lastname: Vandenplas
mesh_terms: D017097:Electric Impedance; D005260:Female; D005764:Gastroesophageal Reflux / Q000628:therapy*; D006801:Humans; D006863:Hydrogen-Ion Concentration; D007223:Infant; D008297:Male; D056888:Patient Positioning; D026741:Physical Therapy Modalities; D016896:Treatment Outcome
keywords: airway clearance techniques; children; physical therapy; respiratory physiotherapy