title: Manganese-Catalyzed Environmentally Benign Dehydrogenative Coupling of Alcohols and Amines to Form Aldimines and H2: A Catalytic and Mechanistic Study.
abstract: The catalytic dehydrogenative coupling of alcohols and amines to form aldimines represents an environmentally benign methodology in organic chemistry. This has been accomplished in recent years mainly with precious-metal-based catalysts. We present the dehydrogenative coupling of alcohols and amines to form imines and H2 that is catalyzed, for the first time, by a complex of the earth-abundant Mn. Detailed mechanistic study was carried out with the aid of NMR spectroscopy, intermediate isolation, and X-ray analysis.
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: Arup
authors.initials: A
authors.lastname: Mukherjee
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: Alexander
authors.initials: A
authors.lastname: Nerush
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: Gregory
authors.initials: G
authors.lastname: Leitus
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: Linda J W
authors.initials: LJ
authors.lastname: Shimon
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: Yehoshoa
authors.initials: Y
authors.lastname: Ben David
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: Noel Angel
authors.initials: NA
authors.lastname: Espinosa Jalapa
authors.affiliation: Department of Organic Chemistry and ‡Department of Chemical Research Support, Weizmann Institute of Science , Rehovot 76100, Israel.
authors.forename: David
authors.initials: D
authors.lastname: Milstein