title: Cutaneous lesions in sporadic angiosarcomas of the breast: a misleading presentation.
abstract: Primary angiosarcoma of the breast is a rare malignant tumour that presents in young women as a painless mass or a sensation of fullness in the breast. To report two cases of primary breast angiosarcoma presenting with unusual and misleading cutaneous lesions. A clinical investigation including ultrasound, MRI and histological examination. In the first patient, the lesion appeared as a superficial, acquired angioma; in the second as an indolent superficial haematoma. This type of primary presentation is exceptional and the benign appearance of the lesion, combined with a lack of breast mass, is misleading. The benign appearance and the pathological aspect of these lesions can lead to misdiagnosis. Comparison of clinical and pathological data is necessary to prevent delay in diagnosis. We believe that all acquired angiomatous lesions developing on the breasts of young women should raise suspicion of angiosarcoma.
authors.affiliation: Anticancer Institute Léon Bérard, Onco-Dermatology, Lyon, France.
authors.forename: Patrick
authors.initials: P
authors.lastname: Combemale
authors.affiliation: Anticancer Institute Léon Bérard, Onco-Dermatology, Lyon, France.
authors.forename: Jessica
authors.initials: J
authors.lastname: Hetu
authors.affiliation: Anatomo-Pathology Department, CHU Le Bocage, Dijon, France.
authors.forename: Marie Hélène
authors.initials: MH
authors.lastname: Aubriot-Lorton
authors.affiliation: Anatomo-Pathology Department, CHU Le Bocage, Dijon, France.
authors.forename: Geraldine
authors.initials: G
authors.lastname: Jeudy
authors.affiliation: Anticancer Institute Léon Bérard, Onco-Dermatology, Lyon, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Chassagne-Clément
authors.affiliation: Anticancer Institute Léon Bérard, Onco-Dermatology, Lyon, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Castillo
authors.affiliation: Anticancer Institute Léon Bérard, Onco-Dermatology, Lyon, France.
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Provensal
authors.affiliation: Anticancer Institute Léon Bérard, Onco-Dermatology, Lyon, France.
authors.forename: Isabelle Ray
authors.initials: IR
authors.lastname: Coquard
authors.affiliation: Anatomo-Pathology Department, CHU Le Bocage, Dijon, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Dalac-Rat
mesh_terms: D001943:Breast Neoplasms / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006394:Hemangiosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D006801:Humans; D008875:Middle Aged; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary*; D055815:Young Adult
keywords: angioma; angiosarcoma; breast; hematoma; tumor