title: Imidazole Derivatives as Potential Therapeutic Agents.
abstract: The imidazole nucleus is inimitable and ubiquitous and it is very well known to play an important role in living organisms. Imidazole derivatives are under intensive scientific exploration due to their diverse and significant pharmacological activities.
  
  
  
  The present paper is an attempt to discuss chemistry, synthetic aspects including click chemistry procedures of imidazoles through systematic literature survey.
  
  
  
  Biological activity profiles of the imidazole derivatives reported in recent scientific literature from 2000 to 2015 have been discussed in detail. It has been found that imidazole derivatives depict appreciable antiinfective activity potential.
  
  
  
  It is anticipated that the information compiled in this paper will be useful and motivating to prospective researchers working on this heterocylic scaffold.
authors.affiliation: Institute of Pharmaceutical Sciences, Kurukshetra University, Kurukshetra-136119, India. archanakuk@gmail.com.
authors.forename: Archana
authors.initials: A
authors.lastname: Sharma
authors.forename: Vipin
authors.initials: V
authors.lastname: Kumar
authors.forename: Rajeev
authors.initials: R
authors.lastname: Kharb
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar
authors.forename: Prabodh Chander
authors.initials: PC
authors.lastname: Sharma
authors.forename: Dharam Pal
authors.initials: DP
authors.lastname: Pathak
mesh_terms: D000700:Analgesics / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000935:Antifungal Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000962:Antimalarials / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000998:Antiviral Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D007093:Imidazoles / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D007239:Infections / Q000188:drug therapy* / Q000382:microbiology / Q000469:parasitology / Q000821:virology; D015394:Molecular Structure
chemical_list: D000700:Analgesics; D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000935:Antifungal Agents; D000962:Antimalarials; D000970:Antineoplastic Agents; D000998:Antiviral Agents; D007093:Imidazoles; C029899:imidazole