title: Urogenital Manifestations of Metastatic Crohn's Disease in Children: Case Series and Review of the Literature.
abstract: Although cutaneous manifestations are the most common extraintestinal manifestation of inflammatory bowel disease, metastatic Crohn's disease (MCD) is rare. MCD is defined as the presence of noncaseating granulomatous inflammation and perivascular infiltrate in the cutaneous tissue that is noncontiguous to the gastrointestinal tract. MCD rarely involves the genitourinary tract in children. When it does, it can present as external genitalia swelling, erythema, plaques, or ulcerations. Here we present three pediatric cases of MCD involving the genitourinary tract. In addition to discussion of the presented cases, we have reviewed the literature on the genitourinary presentation of MCD in the pediatric population.
authors.affiliation: Department of Nephrology and Hypertension, Vanderbilt University, Nashville, TN.
authors.forename: Uzma
authors.initials: U
authors.lastname: Rani
authors.affiliation: D. Brent Polk Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Vanderbilt University, Nashville, TN.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Russell
authors.affiliation: Department of Pediatric Urologic Surgery, Vanderbilt University, Nashville, TN.
authors.forename: Stacy
authors.initials: S
authors.lastname: Tanaka
authors.affiliation: Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN.
authors.forename: Hernan
authors.initials: H
authors.lastname: Correa
authors.affiliation: D. Brent Polk Division of Pediatric Gastroenterology, Hepatology, and Nutrition, Vanderbilt University, Nashville, TN. Electronic address: maribeth.r.nicholson@Vanderbilt.edu.
authors.forename: Maribeth R
authors.initials: MR
authors.lastname: Nicholson
mesh_terms: D002648:Child; D003424:Crohn Disease / Q000150:complications*; D005260:Female; D052776:Female Urogenital Diseases / Q000209:etiology*; D006801:Humans; D008297:Male; D052801:Male Urogenital Diseases / Q000209:etiology*