title: Characterization of nineteen antimony(III) complexes as potent inhibitors of photosystem II, carbonic anhydrase, and glutathione reductase.
abstract: Nineteen antimony(III) complexes were obtained and examined as possible herbicides. Six of these were synthesized for the first time, and their structures were identified using elemental analyses,1H-NMR,13C-NMR, FTIR, LCMS, magnetic susceptibility, and conductivity measurement techniques. For the nineteen examined antimony(III) complexes their most-stable forms were determined by DFT/B3LYP/LanL2DZ calculation method. These compounds were examined for effects on photosynthetic electron transfer and carbonic anhydrase activity of photosystem II, and glutathione reductase from chloroplast as well were investigated. Our results indicated that all antimony(III) complexes inhibited glutathione reductase activity of chloroplast. A number of these also exhibited good inhibitory efficiency of the photosynthetic and carbonic anhydrase activity of Photosystem II.
authors.affiliation: Department of Chemistry, Science Faculty, Gazi University, Teknikokullar, Ankara, Turkey. mkaracan@gazi.edu.tr.
authors.forename: Mehmet Sayım
authors.initials: MS
authors.lastname: Karacan
authors.affiliation: Controlled Photobiosynthesis Laboratory, Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow, Russia, 127276.
authors.forename: Margarita V
authors.initials: MV
authors.lastname: Rodionova
authors.affiliation: Department of Chemistry and Process Engineering, Engineering and Architecture Faculty, Ahi Evran University, Kırşehir, Turkey.
authors.forename: Turgay
authors.initials: T
authors.lastname: Tunç
authors.affiliation: Department of Chemistry, Science Faculty, Gazi University, Teknikokullar, Ankara, Turkey.
authors.forename: Kübra Begüm
authors.initials: KB
authors.lastname: Venedik
authors.affiliation: Department of Chemistry, Science Faculty, Gazi University, Teknikokullar, Ankara, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Mamaş
authors.affiliation: Institute of Basic Biological Problems, Russian Academy of Sciences, Institutskaya Street 2, Pushchino, Moscow Region, Russia, 142290.
authors.forename: Alexandr V
authors.initials: AV
authors.lastname: Shitov
authors.affiliation: Institute of Basic Biological Problems, Russian Academy of Sciences, Institutskaya Street 2, Pushchino, Moscow Region, Russia, 142290.
authors.forename: Sergei K
authors.initials: SK
authors.lastname: Zharmukhamedov
authors.affiliation: Institute of Basic Biological Problems, Russian Academy of Sciences, Institutskaya Street 2, Pushchino, Moscow Region, Russia, 142290.
authors.forename: Vyacheslav V
authors.initials: VV
authors.lastname: Klimov
authors.affiliation: Department of Chemistry, Science Faculty, Gazi University, Teknikokullar, Ankara, Turkey. nkaracan@gazi.edu.tr.
authors.forename: Nurcan
authors.initials: N
authors.lastname: Karacan
authors.affiliation: Controlled Photobiosynthesis Laboratory, Institute of Plant Physiology, Russian Academy of Sciences, Botanicheskaya Street 35, Moscow, Russia, 127276. suleyman.allakhverdiev@gmail.com.|Institute of Basic Biological Problems, Russian Academy of Sciences, Institutskaya Street 2, Pushchino, Moscow Region, Russia, 142290. suleyman.allakhverdiev@gmail.com.|Department of Plant Physiology, Faculty of Biology, M.V. Lomonosov Moscow State University, Leninskie Gory 1-12, Moscow, Russia, 119991. suleyman.allakhverdiev@gmail.com.
authors.forename: Suleyman I
authors.initials: SI
authors.lastname: Allakhverdiev
mesh_terms: D000965:Antimony / Q000737:chemistry / Q000494:pharmacology*; D002257:Carbonic Anhydrase Inhibitors / Q000494:pharmacology*; D002736:Chloroplasts / Q000187:drug effects; D005980:Glutathione Reductase / Q000037:antagonists & inhibitors*; D006540:Herbicides / Q000494:pharmacology; D009682:Magnetic Resonance Spectroscopy; D045332:Photosystem II Protein Complex / Q000187:drug effects*; D013329:Structure-Activity Relationship
chemical_list: D002257:Carbonic Anhydrase Inhibitors; D006540:Herbicides; D045332:Photosystem II Protein Complex; D000965:Antimony; D005980:Glutathione Reductase
keywords: Antimony(III) complexes; Carbonic anhydrase; Glutathione reductase; Inhibitors; Photosystem II (PSII)