title: Paper-based point-of-care testing for diagnosis of dengue infections.
abstract: Dengue endemic is a serious healthcare concern in tropical and subtropical countries. Although well-established laboratory tests can provide early diagnosis of acute dengue infections, access to these tests is limited in developing countries, presenting an urgent need to develop simple, rapid, and robust diagnostic tools. Point-of-care (POC) devices, particularly paper-based POC devices, are typically rapid, cost-effective and user-friendly, and they can be used as diagnostic tools for the prompt diagnosis of dengue at POC settings. Here, we review the importance of rapid dengue diagnosis, current dengue diagnostic methods, and the development of paper-based POC devices for diagnosis of dengue infections at the POC.
authors.affiliation: a The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University , Xi'an , P.R. China.|b Department of Biomedical Engineering , Faculty of Engineering, University of Malaya , Kuala Lumpur , Malaysia.|c Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University , Xi'an , P.R. China.
authors.forename: Jane Ru
authors.initials: JR
authors.lastname: Choi
authors.affiliation: a The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University , Xi'an , P.R. China.|c Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University , Xi'an , P.R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Hu
authors.affiliation: d State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, First Affiliated Hospital, College of Medicine, Zhejiang University , Hangzhou , P.R. China.|e Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases , Hangzhou , P.R. China.|f Institute for Translational Medicine, Zhejiang University , Hangzhou , P.R. China.
authors.forename: ShuQi
authors.initials: S
authors.lastname: Wang
authors.affiliation: g School of Life Sciences, Northwestern Polytechnical University , Xi'an , P.R. China , and.|h Key Laboratory for Space Bioscience and Biotechnology, Northwestern Polytechnical University , Xi'an , P.R. China.
authors.forename: Hui
authors.initials: H
authors.lastname: Yang
authors.affiliation: b Department of Biomedical Engineering , Faculty of Engineering, University of Malaya , Kuala Lumpur , Malaysia.
authors.forename: Wan Abu Bakar
authors.initials: WA
authors.lastname: Wan Abas
authors.affiliation: b Department of Biomedical Engineering , Faculty of Engineering, University of Malaya , Kuala Lumpur , Malaysia.
authors.forename: Belinda
authors.initials: B
authors.lastname: Pingguan-Murphy
authors.affiliation: a The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University , Xi'an , P.R. China.|c Bioinspired Engineering and Biomechanics Center (BEBC), Xi'an Jiaotong University , Xi'an , P.R. China.
authors.forename: Feng
authors.initials: F
authors.lastname: Xu
mesh_terms: D003715:Dengue / Q000175:diagnosis*; D006801:Humans; D010209:Paper; D000067716:Point-of-Care Testing
keywords: Cost-effective; dengue infections; early diagnosis; paper-based device; point-of-care (POC); rapid; user-friendly