title: Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging.
abstract: Efficient morphology modulation of a red AIEgen from pristine microsized rods to nanospheres is achieved via encapsula ting QM-2 (quinolinemalononitrile-2) into hybrid micelles. This novel reagent shows great potential in tumor-targeted bioimaging because of its monodispersion in aqueous systems, the uniform diameter of ≈30 nm, enhanced fluorescence brightness with a large Stokes shift of 190 nm, and strongly increased biocompatibility and photostability.
authors.affiliation: Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China.
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Li
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science & Technology, Shanghai, 200237, P. R. China.
authors.forename: Andong
authors.initials: A
authors.lastname: Shao
authors.affiliation: Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science & Technology, Shanghai, 200237, P. R. China.
authors.forename: Ju
authors.initials: J
authors.lastname: Mei
authors.affiliation: Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China.
authors.forename: Dechao
authors.initials: D
authors.lastname: Niu
authors.affiliation: Lab of Low-Dimensional Materials Chemistry, Key Laboratory for Ultrafine Materials of Ministry of Education, School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China.
authors.forename: Jinlou
authors.initials: J
authors.lastname: Gu
authors.affiliation: State Key Lab of Bioreactor Engineering, East China University of Science and Technology, Shanghai, 200237, P. R. China.
authors.forename: Ping
authors.initials: P
authors.lastname: Shi
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science & Technology, Shanghai, 200237, P. R. China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Zhu
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Laboratory for Advanced Materials and Institute of Fine Chemicals, East China University of Science & Technology, Shanghai, 200237, P. R. China.
authors.forename: He
authors.initials: H
authors.lastname: Tian
authors.affiliation: Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.
authors.forename: Jianlin
authors.initials: J
authors.lastname: Shi
mesh_terms: D045744:Cell Line, Tumor; D006801:Humans; D008823:Micelles; D057054:Molecular Imaging / Q000295:instrumentation*; D054118:Nanospheres / Q000737:chemistry*; D009369:Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D008823:Micelles
keywords: bioimaging; modulation; morphology; photostability; tumor targeting