title: Clearance of donor cell leukemia by means of graft versus leukemia effect: A case report.
abstract: Donor cell leukemia (DCL) is a rare complication of hematopoietic stem cell transplantation (HSCT). Its incidence has been reported between 0.12 and 5%, although the majority of cases are anecdotal. The mechanisms of leukemogenesis in DCL may be distinct from other types of leukemia. Here we describe a case of a 27-year-old woman with a diagnosis of biphenotypic acute leukemia who received a HSCT and developed a DCL. We briefly discuss the possible pathogenesis, diagnosis, and treatment of DCL.
authors.affiliation: a Centro de Hematología y Medicina Interna, Clínica RUIZ , México.|b Universidad Popular Autónoma del Estado de Puebla , México.
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Ruiz-Delgado
authors.affiliation: a Centro de Hematología y Medicina Interna, Clínica RUIZ , México.|c Benemérita Universidad Autónoma de Puebla , México.
authors.forename: Andrés A
authors.initials: AA
authors.lastname: León Peña
authors.affiliation: d Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán , México.
authors.forename: Andrés
authors.initials: A
authors.lastname: Gómez-de-León
authors.affiliation: a Centro de Hematología y Medicina Interna, Clínica RUIZ , México.|b Universidad Popular Autónoma del Estado de Puebla , México.|e Universidad de las Américas Puebla , México.
authors.forename: Guillermo J
authors.initials: GJ
authors.lastname: Ruiz-Argüelles
mesh_terms: D000328:Adult; D005260:Female; D006086:Graft vs Host Disease / Q000209:etiology*; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D007938:Leukemia / Q000150:complications*; D014019:Tissue Donors
keywords: Biphenotypic acute leukemia; Donor cell leukemia; Hematopoietic stem cell transplantation