title: Neurologic manifestations of intravascular large B-cell lymphoma.
abstract: OBJECTIVE
  Intravascular large B-cell lymphoma is a rare subtype of large B-cell lymphoma that affects various organs including the nervous system. The diagnosis is challenging and frequently made at autopsy.
  
  
  RESULTS
  We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated for alternative diagnoses. Three patients were diagnosed at autopsy, one with brain biopsy, and another with muscle biopsy. Muscle was involved in all 3 patients who had muscle tissue available for analysis.
  
  
  CONCLUSIONS
  Our observations suggest that random open muscle biopsy may present a high-yield, less invasive option for the diagnosis of this disorder.
authors.affiliation: Department of Neurology (PT-F, RCB, SGK), Divisions of General Neurology (PT-F/RCB), Neuromuscular Disorders (RCB), Cerebrovascular Diseases (SGK), and Neurological Critical Care (SGK), Division of Oncology (AR), and Department of Pathology and Immunology, Division of Neuropathology (PJC), Washington University School of Medicine, St. Louis, MO.
authors.forename: Pouya
authors.initials: P
authors.lastname: Tahsili-Fahadan
authors.affiliation: Department of Neurology (PT-F, RCB, SGK), Divisions of General Neurology (PT-F/RCB), Neuromuscular Disorders (RCB), Cerebrovascular Diseases (SGK), and Neurological Critical Care (SGK), Division of Oncology (AR), and Department of Pathology and Immunology, Division of Neuropathology (PJC), Washington University School of Medicine, St. Louis, MO.
authors.forename: Armin
authors.initials: A
authors.lastname: Rashidi
authors.affiliation: Department of Neurology (PT-F, RCB, SGK), Divisions of General Neurology (PT-F/RCB), Neuromuscular Disorders (RCB), Cerebrovascular Diseases (SGK), and Neurological Critical Care (SGK), Division of Oncology (AR), and Department of Pathology and Immunology, Division of Neuropathology (PJC), Washington University School of Medicine, St. Louis, MO.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Cimino
authors.affiliation: Department of Neurology (PT-F, RCB, SGK), Divisions of General Neurology (PT-F/RCB), Neuromuscular Disorders (RCB), Cerebrovascular Diseases (SGK), and Neurological Critical Care (SGK), Division of Oncology (AR), and Department of Pathology and Immunology, Division of Neuropathology (PJC), Washington University School of Medicine, St. Louis, MO.
authors.forename: Robert C
authors.initials: RC
authors.lastname: Bucelli
authors.affiliation: Department of Neurology (PT-F, RCB, SGK), Divisions of General Neurology (PT-F/RCB), Neuromuscular Disorders (RCB), Cerebrovascular Diseases (SGK), and Neurological Critical Care (SGK), Division of Oncology (AR), and Department of Pathology and Immunology, Division of Neuropathology (PJC), Washington University School of Medicine, St. Louis, MO.
authors.forename: Salah G
authors.initials: SG
authors.lastname: Keyrouz