title: Complete genome sequence of antibiotic and anticancer agent violacein producing Massilia sp. strain NR 4-1.
abstract: Massilia sp. NR 4-1 was a violacein producing strain newly isolated from topsoil under nutmeg tree, Torreya nucifera in Korean national monument Bijarim Forest. Violacein is a novel class of drug exhibiting anticancer and antibiotic activities originated from l-tryptophan. Here, we present the complete genome of Massilia sp. strain NR 4-1 of 6,361,416bp and total 5285 coding sequences (CDSs) including a complete violacein biosynthesis pathway, vioABCDE. The genome sequence of Massilia sp. NR 4-1 will provide stable and efficient biotechnological applications of violacein production.
authors.affiliation: Department of Systems Biotechnology, Chung-Ang University, Anseong, Republic of Korea.
authors.forename: Nu Ri
authors.initials: NR
authors.lastname: Myeong
authors.affiliation: Department of Systems Biotechnology, Chung-Ang University, Anseong, Republic of Korea.
authors.forename: Hoon Je
authors.initials: HJ
authors.lastname: Seong
authors.affiliation: Department of Systems Biotechnology, Chung-Ang University, Anseong, Republic of Korea.
authors.forename: Hye-Jin
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Systems Biotechnology, Chung-Ang University, Anseong, Republic of Korea. Electronic address: sulwj@cau.ac.kr.
authors.forename: Woo Jun
authors.initials: WJ
authors.lastname: Sul
mesh_terms: D000900:Anti-Bacterial Agents / Q000378:metabolism; D000970:Antineoplastic Agents / Q000378:metabolism; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D001482:Base Composition; D053898:Biosynthetic Pathways; D059646:Genome Size; D016680:Genome, Bacterial; D007211:Indoles / Q000378:metabolism; D042802:Oxalobacteraceae / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D017422:Sequence Analysis, DNA / Q000379:methods*; D012988:Soil Microbiology
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents; D001426:Bacterial Proteins; D007211:Indoles; C063155:violacein
keywords: Antibiotics; Anticancer agent; Complete genome sequence; Massilia sp.; Violacein