title: Corneal toxicity after Ozurdex(®) migration into anterior chamber.
abstract: OBJECTIVE
  To describe a case of corneal toxicity after migration of a dexamethasone implant into the anterior chamber.
  
  
  METHODS
  A 62-year-old man with aphakia and a history of vitrectomy received a dexamethasone implant for a refractory Irvine-Gass syndrome. Thirty days later, the implant migrated into the anterior chamber causing endothelial contact with secondary corneal oedema that justified the removal of the implant without resolution of the oedema.
  
  
  CONCLUSIONS
  Clinical tolerability to dislocated implant is poor in cases with pre-existing corneal oedema, and because of this, it must be removed early. In cases of aphakia and vitrectomy, the increased risk of Ozurdex(®) dislocation justifies performing a prior endothelial count.
authors.affiliation: Servicio de Oftalmología, Complejo Hospitalario Universitario Insular Materno Infantil, de Las Palmas de Gran Canaria, España. Electronic address: laura_bernal15@hotmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Bernal
authors.affiliation: Servicio de Oftalmología, Complejo Hospitalario Universitario Insular Materno Infantil, de Las Palmas de Gran Canaria, España.
authors.forename: B
authors.initials: B
authors.lastname: Estévez
mesh_terms: D060433:Administration, Ophthalmic; D000867:Anterior Chamber; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D001035:Aphakia; D002452:Cell Count; D015715:Corneal Edema / Q000139:chemically induced* / Q000601:surgery; D003907:Dexamethasone / Q000008:administration & dosage / Q000009:adverse effects* / Q000493:pharmacokinetics; D004343:Drug Implants / Q000009:adverse effects; D004728:Endothelium, Corneal / Q000473:pathology; D005119:Extravasation of Diagnostic and Therapeutic Materials / Q000209:etiology*; D058447:Eye Pain / Q000209:etiology; D005548:Foreign-Body Migration / Q000209:etiology* / Q000601:surgery; D005901:Glaucoma / Q000139:chemically induced; D006801:Humans; D008269:Macular Edema / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000139:chemically induced / Q000601:surgery; D014821:Vitrectomy
chemical_list: D000893:Anti-Inflammatory Agents; D004343:Drug Implants; D003907:Dexamethasone
keywords: Corneal oedema; Dexamethasone implant; Edema de córnea; Implante de dexametasona; Migración en cámara anterior; Migration into anterior chamber; Ozurdex(®)