title: Progress in bacterial cellulose matrices for biotechnological applications.
abstract: Bacterial cellulose (BC) is an extracellular polymer produced by many microorganisms. The Komagataeibacter genus is the best producer using semi-synthetic media and agricultural wastes. The main advantages of BC are the nanoporous structure, high water content and free hydroxyl groups. Modification of BC can be made by two strategies: in-situ, during the BC production, and ex-situ after BC purification. In bioprocesses, multilayer BC nanocomposites can contain biocatalysts designed to be suitable for outside to inside cell activities. These nanocomposites biocatalysts can (i) increase productivity in bioreactors and bioprocessing, (ii) provide cell activities does not possess without DNA cloning and (iii) provide novel nano-carriers for cell inside activity and bioprocessing. In nanomedicine, BC matrices containing therapeutic molecules can be used for pathologies like skin burns, and implantable therapeutic devices. In nanoelectronics, semiconductors BC-based using salts and synthetic polymers brings novel films showing excellent optical and photochemical properties.
authors.affiliation: Nanobiomaterials Laboratory, Applied Biotechnology Institute (CINDEFI, UNLP-CONICET CCT La Plata), Department of Chemistry, School of Sciences, Universidad Nacional de La Plata, CP 1900 AJL Ciudad de La Plata, Provincia de Buenos Aires, Argentina.
authors.forename: Maximiliano L
authors.initials: ML
authors.lastname: Cacicedo
authors.affiliation: School of Engineering, Universidad Pontificia Bolivariana, Circular 1 # 70-01, Medellín, Colombia.
authors.forename: M Cristina
authors.initials: MC
authors.lastname: Castro
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Servetas
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Loulouda
authors.initials: L
authors.lastname: Bosnea
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Konstantina
authors.initials: K
authors.lastname: Boura
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Panagiota
authors.initials: P
authors.lastname: Tsafrakidou
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Agapi
authors.initials: A
authors.lastname: Dima
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Antonia
authors.initials: A
authors.lastname: Terpou
authors.affiliation: Food Biotechnology Group, Department of Chemistry, University of Patras, 26500 Patras, Greece.
authors.forename: Athanasios
authors.initials: A
authors.lastname: Koutinas
authors.affiliation: Nanobiomaterials Laboratory, Applied Biotechnology Institute (CINDEFI, UNLP-CONICET CCT La Plata), Department of Chemistry, School of Sciences, Universidad Nacional de La Plata, CP 1900 AJL Ciudad de La Plata, Provincia de Buenos Aires, Argentina. Electronic address: grcastro@gmail.com.
authors.forename: Guillermo R
authors.initials: GR
authors.lastname: Castro
mesh_terms: D016947:Acetobacteraceae / Q000378:metabolism*; D019149:Bioreactors; D001709:Biotechnology / Q000295:instrumentation / Q000379:methods*; D002482:Cellulose / Q000737:chemistry / Q000378:metabolism*; D004800:Enzymes, Immobilized / Q000737:chemistry; D053761:Nanocomposites / Q000737:chemistry*; D050997:Nanomedicine / Q000379:methods
chemical_list: D004800:Enzymes, Immobilized; D002482:Cellulose
keywords: Bacterial cellulose; Biocatalysis; Biocomposites; Bioprocessing; Fermentation