title: The Many Flavors of Model-Based Meta-Analysis: Part I-Introduction and Landmark Data.
abstract: Meta-analysis is an increasingly important aspect of drug development as companies look to benchmark their own compounds with the competition. There is scope to carry out a wide range of analyses addressing key research questions from preclinical through to postregistration. This set of tutorials will take the reader through key model-based meta-analysis (MBMA) methods with this first installment providing a general introduction before concentrating on classical and Bayesian methods for landmark data.
authors.affiliation: Pharmacometrics, Pfizer Ltd Sandwich Kent UK.
authors.forename: M
authors.initials: M
authors.lastname: Boucher
authors.affiliation: Pharmacometrics, Pfizer Ltd Sandwich Kent UK.
authors.forename: M
authors.initials: M
authors.lastname: Bennetts
mesh_terms: D055808:Drug Discovery / Q000379:methods*; D015201:Meta-Analysis as Topic; D008962:Models, Theoretical