title: Sweet syndrome on a patient with autoimmune hepatitis on azathioprine and CMV infection.
abstract: Sweet syndrome (SS) is a rare inflammatory process presenting with painful erythematous skin eruptions, accompanied by fever and neutrophilia. It is associated with upper respiratory infection in fertile women (classic form), malignancy, infections, drugs and autoimmune diseases. Its pathogenesis remains to be determined. Nevertheless, cytokines may have a prominent role, due to a rapid response after corticosteroid administration. We describe a 32-year-old female with autoimmune hepatitis on azathioprine and prednisone, presenting with fever and inflammatory skin eruptions. Histologic examination of the skin lesions showed neutrophilic infiltrations of the dermis, confirming the diagnosis of SS. Concurrently, she tested borderline positive for recent CMV infection.
authors.affiliation: Department of Internal Medicine , Nicosia General Hospital , Nicosia , Cyprus.
authors.forename: Eleni
authors.initials: E
authors.lastname: Xenophontos
authors.affiliation: Department of Internal Medicine , Nicosia General Hospital , Nicosia , Cyprus.
authors.forename: Antreas
authors.initials: A
authors.lastname: Ioannou
authors.affiliation: Department of Internal Medicine , Nicosia General Hospital , Nicosia , Cyprus.
authors.forename: Thrasos
authors.initials: T
authors.lastname: Constantinides
authors.affiliation: Department of Internal Medicine , Nicosia General Hospital , Nicosia , Cyprus.
authors.forename: Eleni
authors.initials: E
authors.lastname: Papanicolaou