title: First description of past Hepatitis B Virus infection acute reactivation occurring in a Human Immunodeficiency Virus infected patient as manifestation of immune reconstitution inflammatory syndrome.
abstract: We report the case of an acute, self-resolving HBV-related hepatitis occurring in a HIV-infected patient carrying isolated anti-HBc antibodies. This acute HBV hepatitis may be considered as a clinical manifestation of a reactivation of HBV during an immune reconstitution inflammatory syndrome. Other hypotheses, even unlikely, are discussed.
authors.affiliation: Unité des Maladies Infectieuses et Tropicales, Département de Médecine Interne (Pr J-F Bergmann), APHP Hôpital Lariboisière, 2, rue Ambroise Paré, 75475 Paris Cedex 10, France.
authors.forename: Clémence
authors.initials: C
authors.lastname: Lepelletier
authors.affiliation: Laboratoire de Virologie (Pr F Simon), APHP Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010 Paris, France; Université Paris Diderot, Sorbonne Paris Cité, Inserm U941, France. Electronic address: maud.salmona@aphp.fr.
authors.forename: Maud
authors.initials: M
authors.lastname: Salmona
authors.affiliation: Laboratoire de Microbiologie (Pr E Cambau), APHP Hôpital Lariboisière, 2, rue Ambroise Paré, 75475 Paris Cedex 10, France.
authors.forename: Béatrice
authors.initials: B
authors.lastname: Berçot
authors.affiliation: Laboratoire de Virologie (Pr F Simon), APHP Hôpital Saint-Louis, 1, avenue Claude Vellefaux, 75010 Paris, France.
authors.forename: Sarah
authors.initials: S
authors.lastname: Maylin
authors.affiliation: Unité des Maladies Infectieuses et Tropicales, Département de Médecine Interne (Pr J-F Bergmann), APHP Hôpital Lariboisière, 2, rue Ambroise Paré, 75475 Paris Cedex 10, France.
authors.forename: Pierre-Olivier
authors.initials: PO
authors.lastname: Sellier
mesh_terms: D000328:Adult; D015658:HIV Infections / Q000150:complications*; D006515:Hepatitis B virus / Q000502:physiology; D019694:Hepatitis B, Chronic / Q000209:etiology* / Q000821:virology; D006801:Humans; D054019:Immune Reconstitution Inflammatory Syndrome / Q000209:etiology*; D008297:Male; D014775:Virus Activation
keywords: HBV reactivation; HIV; IRIS