title: Community-oriented family-based intervention superior to standard treatment in improving depression, hopelessness and functioning among adolescents with any psychosis-risk symptoms.
abstract: The aim of the present study was to compare change in functioning, affective symptoms and level of psychosis-risk symptoms in symptomatic adolescents who were treated either in an early intervention programme based on a need-adapted Family- and Community-orientated integrative Treatment Model (FCTM) or in standard adolescent psychiatric treatment (Treatment As Usual, TAU). 28 pairs were matched by length of follow-up, gender, age, and baseline functioning. At one year after the start of treatment, the matched groups were compared on change in functioning (GAF-M), five psychosis-risk dimensions of the Structured Interview for Psychosis-Risk Syndromes (SIPS), and self-reported anxiety, depression, and hopelessness symptoms (BAI, BDI-II, BHS). FCTM was more effective in improving functioning (20% vs. 6% improvement on GAF-M), as well as self-reported depression (53% vs. 14% improvement on BDI-II) and hopelessness (41% vs. 3% improvement on BHS). However, for psychosis-risk symptoms and anxiety symptoms, effectiveness differences between treatment models did not reach statistical significance. To conclude, in the present study, we found greater improvement in functioning and self-reported depression and hopelessness among adolescents who received a need-adapted Family- and Community-orientated integrative Treatment than among those who were treated in standard adolescent psychiatry.
authors.affiliation: Department of Psychiatry, Helsinki University Central Hospital, Finland Helsinki University Central Hospital, Jorvi Hospital, Department of Psychiatry, Turuntie 150, 02740 Espoo, Finland; Mental Health Unit, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, Finland. Electronic address: niklas.grano@hus.fi.
authors.forename: Niklas
authors.initials: N
authors.lastname: Granö
authors.affiliation: Department of Psychiatry, Helsinki University Central Hospital, Finland Helsinki University Central Hospital, Jorvi Hospital, Department of Psychiatry, Turuntie 150, 02740 Espoo, Finland.
authors.forename: Marjaana
authors.initials: M
authors.lastname: Karjalainen
authors.affiliation: Department of Adolescent Psychiatry, Helsinki University Central Hospital, Välskärinkatu 12, 00260 Helsinki, Finland.
authors.forename: Klaus
authors.initials: K
authors.lastname: Ranta
authors.affiliation: Mental Health Unit, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, Finland.
authors.forename: Maija
authors.initials: M
authors.lastname: Lindgren
authors.affiliation: Department of Psychiatry, Helsinki University Central Hospital, Finland Helsinki University Central Hospital, Jorvi Hospital, Department of Psychiatry, Turuntie 150, 02740 Espoo, Finland.
authors.forename: Mikko
authors.initials: M
authors.lastname: Roine
authors.affiliation: Mental Health Unit, National Institute for Health and Welfare, P.O. Box 30, 00271 Helsinki, Finland.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Therman
mesh_terms: D000293:Adolescent; D000342:Affective Symptoms / Q000523:psychology / Q000628:therapy*; D001007:Anxiety / Q000523:psychology / Q000628:therapy*; D003863:Depression / Q000523:psychology / Q000628:therapy*; D004644:Emotions; D005196:Family Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D011618:Psychotic Disorders / Q000523:psychology / Q000628:therapy*; D012307:Risk Factors
keywords: Comparison; Help seekers; Psychosis-risk symptoms; Symptomatic; Treatment