title: Unusual Presentation of Bladder Paraganglioma: Comparison of (131)I MIBG SPECT/CT and (68)Ga DOTANOC PET/CT.
abstract: Extraadrenal chromaffin cell-related tumors or paragangliomas are rare, especially in the bladder, accounting for less than 1% of cases. We report a 16-year-old boy who presented with hematuria and paroxysmal headache and was found to have a prostatic growth infiltrating the urinary bladder on anatomical imaging. Iodine-131 ((131)I) metaiodobenzylguanidine (MIBG) whole-body scanning and subsequently gallium-68 ((68)Ga) DOTANOC positron emission tomography/computed tomography (PET/CT) were performed. The MIBG scan revealed a non-tracer-avid soft-tissue mass, while DOTANOC PET/CT revealed a tracer-avid primary soft-tissue mass involving the urinary bladder and prostate with metastasis to the iliac lymph nodes. He underwent surgical management; histopathology of the surgical specimen revealed a bladder paraganglioma, whereas the prostate was found to be free of tumor.
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, India.
authors.forename: Tarun Kumar
authors.initials: TK
authors.lastname: Jain
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, India.
authors.forename: Rajender Kumar
authors.initials: RK
authors.lastname: Basher
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, India.
authors.forename: Nitin
authors.initials: N
authors.lastname: Gupta
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, India.
authors.forename: Jaya
authors.initials: J
authors.lastname: Shukla
authors.affiliation: Department of Urology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, India.
authors.forename: Shrawan Kumar
authors.initials: SK
authors.lastname: Singh
authors.affiliation: Department of Nuclear Medicine, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, Haryana and Punjab, India.
authors.forename: Bhagwant Rai
authors.initials: BR
authors.lastname: Mittal
keywords: Bladder paraganglioma; gallium-68 (68Ga) DOTANOC positron emission tomography-computed tomography (PET/CT); iodine-131 (131I) metaiodobenzylguanidine (MIBG)