title: Evaluation of Female Breast Cancer Risk Among the Betel Quid Chewer: A Bio-Statistical Assessment in Assam, India.
abstract: BACKGROUND
  Breast cancer is the most commonly diagnosed cancer among the female population of Assam, India. Chewing of betel quid with or without tobacco is common practice among female population of this region. Moreoverthe method of preparing the betel quid is different from other parts of the country.So matched case control study is conducted to analyse whetherbetel quid chewing plays a significant role in the high incidence of breast cancer occurrences in Assam.
  
  
  METHODS
  Here, controls are matched to the cases by age at diagnosis (±5 years), family income and place of residence with matching ratio 1:1. Conditional logistic regression models and odd ratios (OR) was used to draw conclusions.
  
  
  RESULTS
  It is observed that cases are more habituated to chewing habits than the controls.Further the conditional logistic regression analysis reveals that betel quid chewer faces 2.353 times more risk having breast cancer than the non-chewer with p value 0.0003 (95% CI 1.334-4.150).
  
  
  CONCLUSIONS
  Though the female population in Assam usually does not smoke, the addictive habits typical to this region have equal effect on the occurrence of breast cancer.
authors.affiliation: Central Computational and Numerical Studies, Institute of Advanced Study in Science and Technology , Paschim Boragaon, Guwahati-781035, Assam, India.
authors.forename: Nijara
authors.initials: N
authors.lastname: Rajbongshi
authors.affiliation: Central Computational and Numerical Studies, Institute of Advanced Study in Science and Technology , Paschim Boragaon, Guwahati-781035, Assam, India.
authors.forename: Lipi B
authors.initials: LB
authors.lastname: Mahanta
authors.affiliation: Department of Statistics, Gauhati University , Assam.
authors.forename: Dilip C
authors.initials: DC
authors.lastname: Nath
keywords: Betel Quid; Breast Cancer; Conditional Logistic Regression; Matched Case Control Study; Odds ratio