title: Monte Carlo dosimetry of the IRAsource high dose rate (192)Ir brachytherapy source.
abstract: High-dose-rate (HDR) brachytherapy is a common method for cancer treatment in clinical brachytherapy. Because of the different source designs, there is a need for specific dosimetry data set for each HDR model. The purpose of this study is to obtain detailed dose rate distributions in water phantom for a first prototype HDR (192)Ir brachytherapy source model, IRAsource, and compare with the other published works. In this study, Monte Carlo N-particle (MCNP version 4C) code was used to simulate the dose rate distributions around the HDR source. A full set of dosimetry parameters reported by the American Association of Physicists in Medicine Task Group No. 43U1 was evaluated. Also, the absorbed dose rate distributions in water, were obtained in an along-away look-up table. The dose rate constant, Λ, of the IRAsource was evaluated to be equal to 1.112 ± 0.005 cGy h(-1) U(-1). The results of dosimetry parameters are presented in tabulated and graphical formats and compared with those reported from other commercially available HDR (192)Ir sources, which are in good agreement. This justifies the use of specific data sets for this new source. The results obtained in this study can be used as input data in the conventional treatment planning systems.
authors.affiliation: Department of Nuclear Engineering, Faculty of Advanced Science & Technologies, University of Isfahan, Postal Code: 81756-73441, Isfahan, Iran. a.sarabiasl@ast.ui.ac.ir.
authors.forename: Akbar
authors.initials: A
authors.lastname: Sarabiasl
authors.affiliation: Department of Nuclear Engineering, Faculty of Advanced Science & Technologies, University of Isfahan, Postal Code: 81756-73441, Isfahan, Iran.
authors.forename: Navid
authors.initials: N
authors.lastname: Ayoobian
authors.affiliation: Department of Nuclear Engineering, Faculty of Advanced Science & Technologies, University of Isfahan, Postal Code: 81756-73441, Isfahan, Iran.
authors.forename: Iraj
authors.initials: I
authors.lastname: Jabbari
authors.affiliation: Nuclear Science Research School, Nuclear Science and Technology Research Institute NSTRI, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Poorbaygi
authors.affiliation: Nuclear Science Research School, Nuclear Science and Technology Research Institute NSTRI, Tehran, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Javanshir
mesh_terms: D016880:Anisotropy; D001918:Brachytherapy / Q000379:methods*; D004307:Dose-Response Relationship, Radiation; D006801:Humans; D007496:Iridium Radioisotopes / Q000737:chemistry*; D009010:Monte Carlo Method; D011874:Radiometry; D035501:Uncertainty
chemical_list: D007496:Iridium Radioisotopes
keywords: Brachytherapy; Dosimetry parameters; HDR 192Ir IRAsource; Monte Carlo