title: [Acute hepatotoxicity from intravenous amiodarone in a patient on hemodialysis].
abstract: Amiodarone is a class III antiarrhythmic drug used to treat several tachyarrhythmias. Although toxicity by long-term oral therapy is known, it is rare to observe the acute toxicity correlated to intravenous use. We report an unusual case of acute hepatotoxicity after the initiation of intravenous amiodarone for atrial fibrillation in a patient on regular hemodialysis. Liver enzymes progressively decreased and normalized upon discontinuing the drug. As a result, closely monitoring of liver enzyme is suggested when intravenous amiodarone is prescribed.
authors.forename: Silvia
authors.initials: S
authors.lastname: Bucco
authors.forename: Marta
authors.initials: M
authors.lastname: Arazzi
authors.forename: Federica
authors.initials: F
authors.lastname: Giunta
authors.forename: Xhensila
authors.initials: X
authors.lastname: Grabocka
authors.forename: Maria Olimpia
authors.initials: MO
authors.lastname: Longo
authors.forename: Simona
authors.initials: S
authors.lastname: Silvestri
authors.forename: Nicola
authors.initials: N
authors.lastname: Spetrino
authors.forename: Marco
authors.initials: M
authors.lastname: Tondo
authors.forename: Giacinta
authors.initials: G
authors.lastname: Vigilante
authors.forename: Mario
authors.initials: M
authors.lastname: Bonomini
mesh_terms: D000208:Acute Disease; D000368:Aged; D000638:Amiodarone / Q000008:administration & dosage / Q000009:adverse effects*; D000889:Anti-Arrhythmia Agents / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000209:etiology*; D005260:Female; D006801:Humans; D007262:Infusions, Intravenous; D006435:Renal Dialysis
chemical_list: D000889:Anti-Arrhythmia Agents; D000638:Amiodarone