title: (18)F-FDG PET/CT in multicentric Castleman disease: a case report.
abstract: Castleman disease (CD) is a chronic lymphoproliferative disorder characterized by unexplained enlarged lymph nodes. According to lymph nodes distribution it contains two types of single-centric and multicentric (more than one site) disease. Multicentric Castleman disease (MCD) is rare, and shows unspecific manifestation with high misdiagnosis rate. Here we reported a case of MCD in a 43-year-old male. (18)F-FDG PET/CT imaging demonstrated higher FDG uptake in multiple lymph nodes and slightly FDG uptake in spleen and bone marrow. Right inguinal Lymph node biopsy was taken and the results confirmed CD.
authors.affiliation: 1 Department of Nuclear Medicine, 2 Department of Laboratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
authors.forename: Qiyong
authors.initials: Q
authors.lastname: Ding
authors.affiliation: 1 Department of Nuclear Medicine, 2 Department of Laboratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
authors.forename: Jiexin
authors.initials: J
authors.lastname: Zhang
authors.affiliation: 1 Department of Nuclear Medicine, 2 Department of Laboratory Medicine, First Affiliated Hospital, Nanjing Medical University, Nanjing 210029, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Yang
keywords: 18F-FDG PET/CT; Multicentric Castleman disease (MCD); differential diagnosis; treatment evaluation