title: Recent advances in the management of acromegaly.
abstract: Acromegaly is a rare condition of GH excess associated with significant morbidities (e.g. hypertension, glucose intolerance or diabetes mellitus, cardiac, cerebrovascular, respiratory disease and arthritis) and, when uncontrolled, high mortality. Surgery, medical treatment and radiotherapy remain our therapeutic tools. Advances in these options during the last years have offered further perspectives in the management of patients and particularly those with challenging tumours; the impact of these on the long-term morbidity and mortality remains to be assessed.
authors.affiliation: Department of Endocrinology and Diabetes, Alexandra Hospital, 80 Vas. Sofias St, Athens, 11528, Greece.
authors.forename: Georgia
authors.initials: G
authors.lastname: Ntali
authors.affiliation: Centre for Endocrinology, Diabetes and Metabolism, School of Clinical and Experimental Medicine, University of Birmingham, Wolfson Drive, Edgbaston, Birmingham, B15 2TT, UK.
authors.forename: Niki
authors.initials: N
authors.lastname: Karavitaki
keywords: Acromegaly; adenomectomy; management; radiotherapy; somatostatin analogues