title: Transition-Metal-Free Coupling of Alkynes with α-Bromo Carbonyl Compounds: An Efficient Approach towards β,γ-Alkynoates and Allenoates.
abstract: A direct transition-metal-free coupling between alkynes and α-bromo carbonyl compounds has been developed with ultraviolet (UV) light in aqueous media. This method represents a facile approach to synthetically useful β,γ-alkynyl esters and amides stereoselectively from two readily available starting materials. As an example of the synthetic application of the products, the alkynyl esters were readily converted into allenoates.
authors.affiliation: Department of Chemistry and FQRNT Center for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, QC, H3A 0B8, Canada.
authors.forename: Wenbo
authors.initials: W
authors.lastname: Liu
authors.affiliation: Department of Chemistry and FQRNT Center for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, QC, H3A 0B8, Canada.
authors.forename: Zhengwang
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Department of Chemistry and FQRNT Center for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, QC, H3A 0B8, Canada.
authors.forename: Lu
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Chemistry and FQRNT Center for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, QC, H3A 0B8, Canada.
authors.forename: Haining
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Chemistry and FQRNT Center for Green Chemistry and Catalysis, McGill University, 801 Sherbrooke Street West, Montreal, QC, H3A 0B8, Canada. cj.li@mcgill.ca.
authors.forename: Chao-Jun
authors.initials: CJ
authors.lastname: Li
keywords: allenoates; green chemistry; photochemistry; synthetic methods; water