title: DRESS Syndrome in the ICU: When a Patient Is Treated with Multiple Drugs.
abstract: The Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is life-threatening. It associates a skin condition with hematological and visceral disorders. The DRESS syndrome diagnosis in the intensive care unit (ICU) is difficult as clinical features are nonspecific. Furthermore, the need to treat patients with multiple drugs usually prevents the identification of the causative drug. We report the case of a patient who developed two bouts of DRESS caused by piperacillin-tazobactam, the first being complicated with a distributive shock. Cases of DRESS occurring inside ICU are seldom reported. However, any intensivist may encounter this situation during his career and should be aware of its diagnostic and management specific aspects.
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France.
authors.forename: Florent
authors.identifier: 0000-0003-1699-6757
authors.initials: F
authors.lastname: Moriceau
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France.
authors.forename: Johanne
authors.initials: J
authors.lastname: Prothet
authors.affiliation: Département de Néonatologie et de Réanimation Néonatale, Hôpital Femme Mère Enfant, 32 Avenue Doyen Jean Lépine, 69500 Bron, France.
authors.forename: Benjamin J
authors.initials: BJ
authors.lastname: Blaise
authors.affiliation: Département d'Allergologie et d'Immunologie Clinique, Centre Hospitalier de Lyon-Sud, 165 Chemin du Grand Revoyet, 69310 Pierre-Bénite, France.
authors.forename: Benoit
authors.initials: B
authors.lastname: Ben Said
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Page
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France.
authors.forename: Charles-Eric
authors.initials: CE
authors.lastname: Ber
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France.
authors.forename: Jullien
authors.initials: J
authors.lastname: Crozon
authors.affiliation: Département d'Anesthésie-Réanimation, Hôpital Edouard Herriot, 5 place d'Arsonval, 69003 Lyon, France; Université Claude Bernard Lyon 1, 43 Boulevard du 11 Novembre 1918, 69100 Villeurbanne, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Rimmelé