title: The Influence of Neurocognitive Impairment on HIV Risk Behaviors and Intervention Outcomes among High-Risk Substance Users: A Systematic Review.
abstract: Neurocognitive impairment (NCI) among high-risk substance users poses a substantial barrier to reducing risk behaviors in this population. Previous work suggests that NCI is intertwined in a close, reciprocal relationship with risk behaviors. Not only does substance use worsen cognitive impairment but cognitive impairment may also reduce the efficacy of interventions aimed at reducing risk and improving medication adherence. In this systematic review, we examine the potential impact of substance abuse and cognitive functioning in the context of HIV risk behaviors and risk-reduction intervention outcomes. The findings thus far suggest that, in order to be effective, risk-reduction interventions must take into account the impact of NCI on learning, memory, and behavior.
authors.affiliation: Department of Community Medicine and Health Care, University of Connecticut Health Center, Farmington, CT, USA; Center for Health, Intervention, and Prevention, University of Connecticut, Storrs, CT, USA.
authors.forename: Roman
authors.initials: R
authors.lastname: Shrestha
authors.affiliation: Department of Allied Health Sciences, University of Connecticut , Storrs, CT , USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Copenhaver
keywords: HIV risk behaviors; HIV/AIDS; behavioral interventions; neurocognitive impairment; substance abuse; systematic review