title: Relations between muscle endurance and subjectively reported fatigue, walking capacity, and participation in mildly affected adolescents with cerebral palsy.
abstract: To investigate the relation between muscle endurance and subjectively reported fatigue, walking capacity, and participation in mildly affected adolescents with cerebral palsy (CP) and peers with typical development.
  
  
  
  In this case-control study, knee extensor muscle endurance was estimated from individual load-endurance curves as the load corresponding to a 15-repetition maximum in 17 adolescents with spastic CP (six males, 11 females; age 12-19y) and 18 adolescents with typical development (eight males, 10 females; age 13-19y). Questionnaires were used to assess subjectively reported fatigue (Pediatric Quality of Life Inventory Multidimensional Fatigue Scale) and participation (Life-Habits questionnaire). Walking capacity was assessed using the 6-minute walk test. Relations were determined using multiple regression analyses.
  
  
  
  Muscle endurance related significantly to subjectively reported fatigue and walking capacity in adolescents with CP, while no relations were found for adolescents with typical development (subjectively reported fatigue: regression coefficient β [95% confidence intervals] for CP=23.72 [6.26 to 41.18], for controls=2.72 [-10.26 to 15.69]; walking capacity β for CP=125m [-87 to 337], for controls=2m [-86 to 89]). The 15-repetition maximum did not relate to participation in adolescents with CP.
  
  
  
  Subjectively reported fatigue and reduced walking capacity in adolescents with CP are partly caused by lower muscle endurance of knee extensors. Training of muscle endurance might contribute to reducing the experience of fatigue and improving walking capacity. Reduced muscle endurance seems to have no effect on participation.
authors.affiliation: Department of Rehabilitation Medicine, MOVE Research Institute Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.|Heliomare Rehabilitation, Research and Development, Wijk aan Zee, the Netherlands.
authors.forename: Maaike M
authors.initials: MM
authors.lastname: Eken
authors.affiliation: Heliomare Rehabilitation, Research and Development, Wijk aan Zee, the Netherlands.|Faculty of Behavioural and Movement Sciences, Department of Human Movement Sciences, MOVE Research Institute Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Han
authors.initials: H
authors.lastname: Houdijk
authors.affiliation: Department of Rehabilitation Medicine, MOVE Research Institute Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.|Academy of Human Kinetic Technology, University of Applied Sciences, the Hague, the Netherlands.
authors.forename: Caroline A M
authors.initials: CA
authors.lastname: Doorenbosch
authors.affiliation: Heliomare Rehabilitation, Research and Development, Wijk aan Zee, the Netherlands.
authors.forename: Francisca E M
authors.initials: FE
authors.lastname: Kiezebrink
authors.affiliation: Heliomare Rehabilitation, Research and Development, Wijk aan Zee, the Netherlands.|Coronel Institute of Occupational Health, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Coen A M
authors.initials: CA
authors.lastname: van Bennekom
authors.affiliation: Department of Rehabilitation Medicine, MOVE Research Institute Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Jaap
authors.initials: J
authors.lastname: Harlaar
authors.affiliation: Department of Rehabilitation Medicine, MOVE Research Institute Amsterdam, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Annet J
authors.initials: AJ
authors.lastname: Dallmeijer
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002547:Cerebral Palsy / Q000150:complications* / Q000523:psychology; D005221:Fatigue / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D053580:Muscle Strength / Q000502:physiology*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016138:Walking / Q000502:physiology*; D055815:Young Adult