title: Reduced sleep duration affects body composition, dietary intake and quality of life in obese subjects.
abstract: OBJECTIVE
  Sleep duration has emerged as a crucial factor affecting body weight and feeding behaviour. The aim of our study was to explore the relationship among sleep duration, body composition, dietary intake, and quality of life (QoL) in obese subjects.
  
  
  METHODS
  Body composition was assessed by DXA. "Sensewear Armband" was used to evaluate sleep duration. SF-36 questionnaire was used to evaluate quality of life (QoL). A 3-day dietary record was administered. Subjects were divided into 2 groups: sleep duration > and ≤300 min/day.
  
  
  RESULTS
  137 subjects (105 women and 32 men), age: 49.8 ± 12.4 years, BMI: 38.6 ± 6.7 kg/m(2), were enrolled. Sleep duration was ≤300 min in 30.6 % of subjects. Absolute and relative fat mass (FM) (40.5 ± 9 vs. 36.5 ± 9.1 kg; 40.2 ± 4.7 vs. 36.9 ± 5.6 %), and truncal fat mass (19.2 ± 6.1 vs. 16.6 ± 5 kg; 38.6 ± 5.3 vs. 35.2 ± 5.5 %) were higher in subjects sleeping ≤300 min when compared to their counterparts (all p < 0.05), whereas just a tendency towards a higher BMI was observed (p = 0.077). Even though energy intake was not different between groups, subjects sleeping ≤300 min reported a higher carbohydrate consumption per day (51.8 ± 5.1 vs. 48.4 ± 9.2 %, p = 0.038). SF-36 total score was lower in subjects sleeping ≤300 min (34.2 ± 17.8 vs. 41.4 ± 12.9, p = 0.025). Sleep duration was negatively associated with FM (r = -0.25, p = 0.01) and SF-36 total score (r = -0.31, p < 0.001). The inverse association between sleep duration and SF-36 total score was confirmed by the regression analysis after adjustment for BMI and fat mass (R = 0.43, R (2) = 0.19, p = 0.012).
  
  
  CONCLUSIONS
  Reduced sleep duration negatively influences body composition, macronutrient intake, and QoL in obese subjects.
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy. eleonora.poggiogalle@uniroma1.it.
authors.forename: Eleonora
authors.initials: E
authors.lastname: Poggiogalle
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Carla
authors.initials: C
authors.lastname: Lubrano
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Lucio
authors.initials: L
authors.lastname: Gnessi
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Marocco
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Di Lazzaro
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Giampaolo
authors.initials: G
authors.lastname: Polidoro
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Federica
authors.initials: F
authors.lastname: Luisi
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Gianluca
authors.initials: G
authors.lastname: Merola
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Stefania
authors.initials: S
authors.lastname: Mariani
authors.affiliation: Endocrinology Unit, Department of Movement, Human and Health Sciences, University of "Foro Italico", Rome, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Migliaccio
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Lenzi
authors.affiliation: Medical Pathophysiology, Food Science and Endocrinology Section, Food Science and Human Nutrition Research Unit, Department of Experimental Medicine, "Sapienza" University, Rome, Piazzale Aldo Moro, 5, 00185, Rome, Italy.
authors.forename: Lorenzo M
authors.initials: LM
authors.lastname: Donini
mesh_terms: D000328:Adult; D001823:Body Composition / Q000502:physiology*; D001835:Body Weight / Q000502:physiology; D002149:Energy Intake / Q000502:physiology*; D005247:Feeding Behavior / Q000502:physiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology*; D011788:Quality of Life; D012890:Sleep / Q000502:physiology*; D011795:Surveys and Questionnaires
keywords: Body composition; Dietary intake; Obesity; Quality of life; Sleep