title: A Multibody Knee Model Corroborates Subject-Specific Experimental Measurements of Low Ligament Forces and Kinematic Coupling During Passive Flexion.
abstract: A multibody model of the knee was developed and the predicted ligament forces and kinematics during passive flexion corroborated subject-specific measurements obtained from a human cadaveric knee that was tested using a robotic manipulator. The model incorporated a novel strategy to estimate the slack length of ligament fibers based on experimentally measured ligament forces at full extension and included multifiber representations for the cruciates. The model captured experimentally measured ligament forces (≤ 5.7 N root mean square (RMS) difference), coupled internal rotation (≤ 1.6 deg RMS difference), and coupled anterior translation (≤ 0.4 mm RMS difference) through 130 deg of passive flexion. This integrated framework of model and experiment improves our understanding of how passive structures, such as ligaments and articular geometries, interact to generate knee kinematics and ligament forces.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Kia
authors.forename: Kevin
authors.initials: K
authors.lastname: Schafer
authors.forename: Joseph
authors.initials: J
authors.lastname: Lipman
authors.forename: Michael
authors.initials: M
authors.lastname: Cross
authors.forename: David
authors.initials: D
authors.lastname: Mayman
authors.forename: Andrew
authors.initials: A
authors.lastname: Pearle
authors.forename: Thomas
authors.initials: T
authors.lastname: Wickiewicz
authors.forename: Carl
authors.initials: C
authors.lastname: Imhauser
mesh_terms: D001696:Biomechanical Phenomena; D006801:Humans; D007717:Knee / Q000502:physiology*; D008022:Ligaments / Q000502:physiology*; D008297:Male; D055595:Mechanical Phenomena; D009068:Movement; D066230:Patient-Specific Modeling; D016059:Range of Motion, Articular; D012399:Rotation; D013977:Tibia; D055815:Young Adult