title: An expedient sequential one-pot four component synthesis of novel steroidal spiro-pyrrolidine heterocycles in ionic liquid.
abstract: A facile one-pot synthesis of novel steroidal dispiro-indenoquinoxaline pyrrolidines via multicomponent-[3+2]-cycloaddition of azomethine ylides in ionic liquid is described. The structure of cycloadduct is confirmed by IR, (1)H NMR, (13)C NMR, high resolution mass spectroscopy and elemental analysis.
authors.affiliation: Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India.
authors.forename: D
authors.initials: D
authors.lastname: Gavaskar
authors.affiliation: Institute of Molecular and Cellular Biology (IBMC), University of Strasbourg, Strasbourg, France.
authors.forename: A R Suresh
authors.initials: AR
authors.lastname: Babu
authors.affiliation: Department of Organic Chemistry, University of Madras, Guindy Campus, Chennai, India. Electronic address: ragharaghunathan@yahoo.com.
authors.forename: R
authors.initials: R
authors.lastname: Raghunathan
authors.affiliation: Department of Inorganic Chemistry, University of Madras, Guindy Campus, Chennai, India.
authors.forename: M
authors.initials: M
authors.lastname: Dharani
authors.affiliation: Department of Inorganic Chemistry, University of Madras, Guindy Campus, Chennai, India.
authors.forename: S
authors.initials: S
authors.lastname: Balasubramanian
mesh_terms: D060326:Chemistry Techniques, Synthetic; D052578:Ionic Liquids / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry*; D013256:Steroids / Q000138:chemical synthesis* / Q000737:chemistry*
chemical_list: D052578:Ionic Liquids; D011759:Pyrrolidines; D013141:Spiro Compounds; D013256:Steroids; C032519:pyrrolidine
keywords: Azomethine ylide; Cycloaddition; Estrone; Indenoquinoxaline; Ionic liquid; Steroidal pyrrolidine