title: Genotoxicity in Mice Following AAV Gene Delivery: A Safety Concern for Human Gene Therapy?
authors.affiliation: Molecular Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Randy J
authors.initials: RJ
authors.lastname: Chandler
authors.affiliation: Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: LaFave
authors.affiliation: Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Gaurav K
authors.initials: GK
authors.lastname: Varshney
authors.affiliation: Translational and Functional Genomics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA.
authors.forename: Shawn M
authors.initials: SM
authors.lastname: Burgess
authors.affiliation: Molecular Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland, USA. Electronic address: venditti@mail.nih.gov.
authors.forename: Charles P
authors.initials: CP
authors.lastname: Venditti
mesh_terms: D000818:Animals; D004249:DNA Damage; D000229:Dependovirus / Q000276:immunology / Q000502:physiology*; D004353:Drug Evaluation, Preclinical; D015316:Genetic Therapy / Q000009:adverse effects*; D006801:Humans; D007111:Immunity, Cellular; D056724:Immunity, Humoral; D051379:Mice