title: Endoscopic Radiofrequency Ablation-Assisted Resection of Juvenile Nasopharyngeal Angiofibroma: Comparison with Traditional Endoscopic Technique.
abstract: To evaluate the feasibility of radiofrequency surgical instrumentation for endoscopic resection of juvenile nasopharyngeal angiofibroma (JNA) and to test the hypothesis that endoscopic radiofrequency ablation-assisted (RFA) resection will have superior intraoperative and/or postoperative outcomes as compared with traditional endoscopic (TE) resection techniques.
  
  
  
  Case series with chart review.
  
  
  
  Two tertiary care pediatric hospitals.
  
  
  
  Twenty-nine pediatric patients who underwent endoscopic transnasal resection of JNA from January 2000 to December 2014.
  
  
  
  Twenty-nine patients underwent RFA (n = 13) or TE (n = 16) JNA resection over the 15-year study period. Mean patient age was not statistically different between the 2 groups (P = .41); neither was their University of Pittsburgh Medical Center classification stage (P = .79). All patients underwent preoperative embolization. Mean operative times were not statistically different (P = .29). Mean intraoperative blood loss and the need for a transfusion were also not statistically different (P = .27 and .47, respectively). Length of hospital stay was not statistically different (P = .46). Recurrence rates did not differ between groups (P = .99) over a mean follow-up period of 2.3 years.
  
  
  
  There were no significant differences between RFA and TE resection in intraoperative or postoperative outcome parameters.
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA Division of Pediatric Otolaryngology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
authors.forename: Eamon J
authors.initials: EJ
authors.lastname: McLaughlin
authors.affiliation: Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, USA Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Cunningham
authors.affiliation: Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA Division of Pediatric Otolaryngology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
authors.forename: Ken
authors.initials: K
authors.lastname: Kazahaya
authors.affiliation: Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, USA Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Julianna
authors.initials: J
authors.lastname: Hsing
authors.affiliation: Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, USA Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Kawai
authors.affiliation: Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, USA Department of Otolaryngology, Harvard Medical School, Boston, Massachusetts, USA eelam.adil@childrens.harvard.edu.
authors.forename: Eelam A
authors.initials: EA
authors.lastname: Adil
mesh_terms: D000293:Adolescent; D018322:Angiofibroma / Q000601:surgery*; D017115:Catheter Ablation / Q000379:methods*; D004724:Endoscopy / Q000379:methods*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D008297:Male; D009303:Nasopharyngeal Neoplasms / Q000601:surgery*; D011846:Radio Waves; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: endoscopic resection; epistaxis; juvenile nasopharyngeal angiofibroma; radiofrequency ablation; skull base tumor