title: Stereoselective Synthesis of 2-(β-C-Glycosyl)glycals: Access to Unusual β-C-Glycosides from 3-Deoxyglycals.
abstract: A novel method for the highly stereoselective synthesis of β-(1→2)-C-saccharides employing 3-deoxy- and 3-C-branched glycals as hermaphroditic substrates is revealed. The generality of the C-C bond formation reaction between the two sugar units is evaluated. The developed methodology is successfully applied to the synthesis of biologically significant subunits that are present in various natural products, which include mixed C-disaccharides with adjacent THP-THF rings, C-aryl glycosides, and highly functionalized β-C-glycosides.
authors.affiliation: School of Chemistry, University of Hyderabad , Hyderabad 500 046, India.
authors.forename: Gadi Madhusudhan
authors.initials: GM
authors.lastname: Reddy
authors.affiliation: School of Chemistry, University of Hyderabad , Hyderabad 500 046, India.
authors.forename: Boddu Uma
authors.initials: BU
authors.lastname: Maheswara Rao
authors.affiliation: School of Chemistry, University of Hyderabad , Hyderabad 500 046, India.
authors.forename: Perali Ramu
authors.initials: PR
authors.lastname: Sridhar