title: Direct identification of prohibited substances in cosmetics and foodstuffs using ambient ionization on a miniature mass spectrometry system.
abstract: Significantly simplified work flows were developed for rapid analysis of various types of cosmetic and foodstuff samples by employing a miniature mass spectrometry system and ambient ionization methods. A desktop Mini 12 ion trap mass spectrometer was coupled with paper spray ionization, extraction spray ionization and slug-flow microextraction for direct analysis of Sudan Reds, parabens, antibiotics, steroids, bisphenol and plasticizer from raw samples with complex matrices. Limits of detection as low as 5 μg/kg were obtained for target analytes. On-line derivatization was also implemented for analysis of steroid in cosmetics. The developed methods provide potential analytical possibility for outside-the-lab screening of cosmetics and foodstuff products for the presence of illegal substances.
authors.affiliation: Chinese Academy of Inspection and Quarantine, Beijing 100176, China; Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Ma
authors.affiliation: Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Bai
authors.affiliation: Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
authors.forename: Wentao
authors.initials: W
authors.lastname: Li
authors.affiliation: Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.affiliation: Chinese Academy of Inspection and Quarantine, Beijing 100176, China.
authors.forename: Xinshi
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA; Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: R Graham
authors.initials: RG
authors.lastname: Cooks
authors.affiliation: Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN 47907, USA; Department of Chemistry, Purdue University, West Lafayette, IN 47907, USA; Department of Electrical and Computer Engineering, Purdue University, West Lafayette, IN 47907, USA; Center for Analytical Instrumentation Development, Purdue University, West Lafayette, IN 47907, USA. Electronic address: ouyang@purdue.edu.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Ouyang
mesh_terms: D003358:Cosmetics / Q000737:chemistry*; D005506:Food Contamination / Q000032:analysis*; D013058:Mass Spectrometry / Q000379:methods*
chemical_list: D003358:Cosmetics
keywords: Ambient ionization; Cosmetics; Extraction spray; Foodstuffs; Miniature ion trap mass spectrometer; Paper spray; Parabens; Plasticizer; Slug-flow microextraction; Steroids; Sudan Red