title: Evidence-based guidelines: Improving AGREEment on consistence evaluation.
abstract: Modern clinical practice relies on evidence-based medicine (EBM) and evidence-based guidelines (EBGs). The critical evaluation of EBGs value is therefore an essential step to further improve clinical practice. In our opinion, correlating levels of evidence and grades of recommendation can be an easy tool to quickly display internal consistence of EBGs.
authors.affiliation: University Campus Bio-Medico, Department of Medical Oncology, Rome, Italy.
authors.forename: Bruno
authors.initials: B
authors.lastname: Vincenzi
authors.affiliation: University Campus Bio-Medico, Department of Medical Oncology, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Napolitano
authors.affiliation: University Campus Bio-Medico, Department of Medical Oncology, Rome, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Santini
authors.affiliation: Istituto di ricovero e cura a carattere scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo, Medical Oncology Unit, Foggia, Italy.
authors.forename: Evaristo
authors.initials: E
authors.lastname: Maiello
authors.affiliation: Mario Negri Institute for Pharmacological Research, Milan, Italy.
authors.forename: Valter
authors.initials: V
authors.lastname: Torri
authors.affiliation: University Campus Bio-Medico, Department of Medical Oncology, Rome, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Tonini
keywords: AGREE; Bone metastasis; EBG; EBM; Guideline