title: Cortical morphometry in frontoparietal and default mode networks in math-gifted adolescents.
abstract: Math-gifted subjects are characterized by above-age performance in intelligence tests, exceptional creativity, and high task commitment. Neuroimaging studies reveal enhanced functional brain organization and white matter microstructure in the frontoparietal executive network of math-gifted individuals. However, the cortical morphometry of these subjects remains largely unknown. The main goal of this study was to compare the cortical morphometry of math-gifted adolescents with that of an age- and IQ-matched control group. We used surface-based methods to perform a vertex-wise analysis of cortical thickness and surface area. Our results show that math-gifted adolescents present a thinner cortex and a larger surface area in key regions of the frontoparietal and default mode networks, which are involved in executive processing and creative thinking, respectively. The combination of reduced cortical thickness and larger surface area suggests above-age neural maturation of these networks in math-gifted individuals. Hum Brain Mapp 37:1893-1902, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Departamento De Bioingeniería E Ingeniería Aeroespacial, Universidad Carlos III Madrid, Madrid, Spain.|Centro De Investigación Biomédica En Red De Salud Mental (CIBERSAM), Madrid, Spain.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Navas-Sánchez
authors.affiliation: Departamento De Bioingeniería E Ingeniería Aeroespacial, Universidad Carlos III Madrid, Madrid, Spain.
authors.forename: Susana
authors.initials: S
authors.lastname: Carmona
authors.affiliation: Departamento De Bioingeniería E Ingeniería Aeroespacial, Universidad Carlos III Madrid, Madrid, Spain.|Centro De Investigación Biomédica En Red De Salud Mental (CIBERSAM), Madrid, Spain.
authors.forename: Yasser
authors.initials: Y
authors.lastname: Alemán-Gómez
authors.affiliation: Philips Healthcare, Clinical Science, Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Sánchez-González
authors.affiliation: Departamento De Radiología, Hospital General Universitario Gregorio Marañón, Instituto De Investigación Biomédica Gregorio Marañón, Madrid, Spain.
authors.forename: Juan
authors.initials: J
authors.lastname: Guzmán-de-Villoria
authors.affiliation: Departamento De Psiquiatría Infantil Y Adolescente, Hospital General Universitario Gregorio Marañón, Instituto De Investigación Biomédica Gregorio Marañón, Madrid, Spain.
authors.forename: Carolina
authors.initials: C
authors.lastname: Franco
authors.affiliation: Departamento De Psiquiatría Infantil Y Adolescente, Hospital General Universitario Gregorio Marañón, Instituto De Investigación Biomédica Gregorio Marañón, Madrid, Spain.|Centro De Referencia Estatal De Atención Al Daño Cerebral (CEADAC), Madrid, Spain.
authors.forename: Olalla
authors.initials: O
authors.lastname: Robles
authors.affiliation: Centro De Investigación Biomédica En Red De Salud Mental (CIBERSAM), Madrid, Spain.|Departamento De Psiquiatría Infantil Y Adolescente, Hospital General Universitario Gregorio Marañón, Instituto De Investigación Biomédica Gregorio Marañón, Madrid, Spain.|Departamento De Psiquiatría, Facultad De Medicina, Universidad Complutense De Madrid, Madrid, Spain.
authors.forename: Celso
authors.initials: C
authors.lastname: Arango
authors.affiliation: Departamento De Bioingeniería E Ingeniería Aeroespacial, Universidad Carlos III Madrid, Madrid, Spain.|Centro De Investigación Biomédica En Red De Salud Mental (CIBERSAM), Madrid, Spain.|Unidad De Medicina Y Cirugía Experimental, Hospital General Universitario Gregorio Marañón, Instituto De Investigación Sanitaria Gregorio Marañón, Madrid, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Desco
mesh_terms: D000293:Adolescent; D001931:Brain Mapping; D002648:Child; D002672:Child, Gifted; D005260:Female; D005625:Frontal Lobe / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007361:Intelligence Tests; D008279:Magnetic Resonance Imaging; D008297:Male; D008433:Mathematics; D008959:Models, Neurological; D010296:Parietal Lobe / Q000000981:diagnostic imaging*; D018709:Statistics, Nonparametric
keywords: area; cortex; default mode; frontoparietal; math-giftedness; thickness