title: Dual-role FilmArray® diagnostics for high-impact viral diseases.
abstract: In this study, we explored the potential utility of the human-focused FilmArray® Respiratory Panel for the diagnosis of a broad range of influenza viruses of veterinary concern as compared with the standard portfolio of recommended TaqMan®-based diagnostic tests. In addition, we discuss some potential operational advantages associated with the use of such integrated sample extraction, amplification and analysis devices in the context of a future long-term, dual-role strategy for the detection of emergency diseases of both human and veterinary concern.
authors.affiliation: Defence Science and Technology Organisation, Melbourne, Victoria, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Dorsch
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia. Brian.Meehan@csiro.au.
authors.forename: B
authors.initials: B
authors.lastname: Meehan
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: W P
authors.initials: WP
authors.lastname: Michalski
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: H G
authors.initials: HG
authors.lastname: Heine
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: A J
authors.initials: AJ
authors.lastname: Foord
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Carlile
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: S
authors.initials: S
authors.lastname: McCullough
authors.affiliation: CSIRO, Australian Animal Health Laboratory, Geelong, Victoria, 3220, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Zuelke
mesh_terms: D000818:Animals; D001717:Birds; D004630:Emergencies / Q000662:veterinary; D006801:Humans; D005585:Influenza in Birds / Q000175:diagnosis* / Q000821:virology; D007251:Influenza, Human / Q000175:diagnosis* / Q000821:virology; D009975:Orthomyxoviridae / Q000302:isolation & purification*; D009976:Orthomyxoviridae Infections / Q000175:diagnosis / Q000662:veterinary* / Q000821:virology; D010865:Pilot Projects; D000067716:Point-of-Care Testing; D016133:Polymerase Chain Reaction / Q000379:methods; D012016:Reference Values; D013552:Swine; D013553:Swine Diseases / Q000175:diagnosis* / Q000821:virology
keywords: PCR; emergency disease preparedness; influenza viruses; molecular diagnostics