title: Other Gynecologic Pathology in Endometrial Cancer Patients.
abstract: BACKGROUND
  To evaluate the prevalence and features of other gynecologic or surgical lesions in endometrial cancer (EMC) patients.
  
  
  METHODS
  Clinico-pathological data of EMC patients who were treated in the institution from 1995 to 2012 were collected. Data collected were age, stage of disease according to the FIGO 2009 criteria (FIGO), histopathology, tumor grade, adjuvant therapy, other gynecologic or surgical lesions, follow-up period, and living status.
  
  
  RESULTS
  The mean age of 396 patients was 56.7 ± 10.64 years. Abnormal uterine bleeding was the most common presenting symptom (90.1%). Bleeding was accompanied with pelvic mass in 7.7% and 5.4% had only a pelvic mass. Abnormal cervical cytology was found in 3.8%. Approximately 75% had early stage diseases and 86% had endometrioid histology. We found 55.8% of EMC patients had other gynecologic lesions: 89.6% benign and 9.5% malignant. Some 4.5% had pre-invasive cervical/vulva/vagina lesions. The two most common gynecologic lesions were myoma uteri and ovarian tumors. Focusing on the latter, approximately 14% were benign while 8% were malignant. Among 364 patients with available data, surgical lesions were found in 11.8%, 5.7% benign and 9.2% malignant. The most common benign surgical condition was chronic appendicitis while breast and colon cancers were the two most common malignant lesions found.
  
  
  CONCLUSIONS
  More than half of EMC patients had other gynecologic lesions including benign and malignant tumors. Surgical lesions were also found in more than one-tenth of patients. Careful pre-operative evaluation and intra-operative inspection are advised for proper management and better prognosis.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Bangkok, Thailand E-mail : jak020@hotmail.com.
authors.forename: Jakkapan
authors.initials: J
authors.lastname: Khunnarong
authors.forename: Siriwan
authors.initials: S
authors.lastname: Tangjitgamol
authors.forename: Sunamchok
authors.initials: S
authors.lastname: Srijaipracharoen
mesh_terms: D000328:Adult; D016889:Endometrial Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D005831:Genital Diseases, Female / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000209:etiology / Q000473:pathology*; D011183:Postoperative Complications; D011379:Prognosis; D014594:Uterine Neoplasms / Q000209:etiology / Q000473:pathology*