title: Cardiovascular risk factors, micro and macrovascular complications at diagnosis in patients with young onset type 2 diabetes in India: CINDI 2.
abstract: BACKGROUND
  Type 2 diabetes mellitus (T2DM) in young adults is increasing in India. Data on the prevalence of cardiovascular (CV) risk factors and complications associated with young-onset T2DM (YOD) at the time of diagnosis of diabetes are limited. This data can aid in aggressive diabetes management, CV risk reduction, and prevention of complications.
  
  
  OBJECTIVE
  To determine the prevalence of CV risk factors, micro and macrovascular complications in patients with newly diagnosed YOD. To assess the percentage of patients who require statin therapy based on current American Diabetes Association (ADA) guidelines.
  
  
  METHODS
  This was a retrospective cross-sectional study of 1500 patients with newly detected YOD across seven centers from 2013 to 2015.
  
  
  METHODS
  Patients were evaluated for complications of diabetes and CV risk factors such as body mass index (BMI), hypertension, dyslipidemia, and smoking.
  
  
  METHODS
  Measurements have been presented as mean ± standard deviation; results on categorical measurements have been presented in percentages.
  
  
  RESULTS
  The mean age, glycated hemoglobin and BMI were 34.7 ± 4.2 years, 9.9 ± 2.4%, and 26.8 ± 4.7 kg/m(2). Hypertension, dyslipidemia, BMI >23 kg/m(2), and smoking were presented in 27.6%, 62.4%, 84.2%, and 24%. Diabetic retinopathy, neuropathy, and nephropathy were seen in 5.1%, 13.2%, and 0.9%. Ischemic heart disease, peripheral vascular disease, and stroke were presented in 0.7%, 2%, and 0.1%. As per current guidelines, 95.33% needed statin therapy.
  
  
  CONCLUSIONS
  This study demonstrates that patients with YOD have micro and macrovascular complications at diagnosis. Nearly, every patient required a statin to reduce CV risk. This highlights the importance of screening patients with YOD for CV risk factors and complications of diabetes at the time of diagnosis.
authors.affiliation: Diacon Hospital, Bengaluru, Karnataka, India.
authors.forename: Bhavana
authors.initials: B
authors.lastname: Sosale
authors.affiliation: Diacon Hospital, Bengaluru, Karnataka, India.
authors.forename: Aravind R
authors.initials: AR
authors.lastname: Sosale
authors.affiliation: Dr. Mohan's Diabetes Specialities Centre, Chennai, Tamil Nadu, India.
authors.forename: Anjana R
authors.initials: AR
authors.lastname: Mohan
authors.affiliation: CDEC, Bengaluru, Karnataka, India.
authors.forename: Prassanna M
authors.initials: PM
authors.lastname: Kumar
authors.affiliation: Diabetes and Hormones Centre, Ahmedabad, Gujarat, India.
authors.forename: Banshi
authors.initials: B
authors.lastname: Saboo
authors.affiliation: Diabetes Hospital, Rajahmundry, Andhra Pradesh, India.
authors.forename: Sai
authors.initials: S
authors.lastname: Kandula
keywords: Cardiovascular risk; complications; dyslipidemia; neuropathy; retinopathy; type 2 diabetes; young onset diabetes