title: Is hand-grip another culprit for the risk of fractures in HIV-positive patients?
abstract: Risk of bone fractures in patients with HIV infection is greater than in the general population, particularly in those co-infected with hepatitis viruses. We compared bone mineral density (BMD) and muscular strength, measured by hand grip test (HG), in HIV mono-infected and co-infected patients. T-score values were lower in HIV patients co-infected with hepatitis viruses vs. mono-infected individuals. Since no significant correlations between HG and T-scores were found, we hypothesize that these factors belong, at least in part, to independent pathways, so both should be taken into account as risks for fragility fractures. Larger prospective studies are needed to confirm this hypothesis.
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Maria Concetta
authors.initials: MC
authors.lastname: Postorino
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Torti
authors.affiliation: Clinical Nutrition Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Carè
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Pisani
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Alessio
authors.initials: A
authors.lastname: Strazzulla
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Vittoria
authors.initials: V
authors.lastname: Vaccaro
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Costa
authors.affiliation: Clinical Nutrition Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Provenzano
authors.affiliation: Infectious Diseases Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Mazzitelli
authors.affiliation: Clinical Nutrition Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Arturo
authors.initials: A
authors.lastname: Pujia
authors.affiliation: Clinical Nutrition Unit, "Magna Graecia" University, Catanzaro, Italy.
authors.forename: Tiziana
authors.initials: T
authors.lastname: Montalcini
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density; D060085:Coinfection; D005260:Female; D050723:Fractures, Bone / Q000209:etiology*; D015658:HIV Infections / Q000150:complications*; D006230:Hand Injuries / Q000209:etiology*; D018737:Hand Strength; D006526:Hepatitis C / Q000150:complications; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
keywords: Bone fractures; Bone mineral density; HCV; HIV; Hand grip; Osteoporosis