title: Cellular processes underlying cerebral cavernous malformations: Autophagy as another point of view.
abstract: A growing amount of evidence indicates that autophagy plays a pivotal role in a plethora of human pathological conditions. We have recently broadened the list of the so-called autophagy-related diseases, describing the involvement of defective autophagy in the pathogenesis of cerebral cavernous malformations.
authors.affiliation: a Department of Morphology , Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara , Ferrara , Italy.
authors.forename: Saverio
authors.initials: S
authors.lastname: Marchi
authors.affiliation: b Department of Clinical and Biological Sciences , University of Torino , Torino , Italy.
authors.forename: Saverio Francesco
authors.initials: SF
authors.lastname: Retta
authors.affiliation: a Department of Morphology , Surgery and Experimental Medicine, Section of Pathology, Oncology and Experimental Biology, University of Ferrara , Ferrara , Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Pinton
mesh_terms: D001343:Autophagy; D020786:Hemangioma, Cavernous, Central Nervous System / Q000473:pathology*; D006801:Humans; D008954:Models, Biological
keywords: CCM; MTOR; ROS; autophagy; endothelial-to-mesenchymal transition (EndMt); pharmacological therapy