title: [Diagnostic value of prealbumin for severe necrotizing enterocolitis].
abstract: OBJECTIVE
  To study the clinical features of severe neonatal necrotizing enterocolitis (NEC), and to investigate the diagnostic value of prealbumin (PA) in neonates with severe NEC.
  
  
  METHODS
  The clinical data and results of routine blood test and blood biochemical test of 40 neonates with NEC (29 neonates with NEC II and 11 with NEC III) were analyzed. The multivariate logistic regression analysis and receiver operating characteristic (ROC) curve were applied to investigate the value of PA in the diagnosis of severe NEC.
  
  
  RESULTS
  The multivariate logistic regression analysis showed that PA was an important index for the diagnosis of severe NEC (&ge;IIB). The ROC analysis showed that in the diagnosis of severe NEC (&ge;IIB), PA had high sensitivity (0.870) and specificity (0.647).
  
  
  CONCLUSIONS
  PA has a good value in the diagnosis of severe NEC.
authors.affiliation: Department of Neonatolgy, Nanjing Children&prime;s Hospital of Nanjing Medical University, Nanjing 210008, China. yy860508@163.com.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Pan
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Zhou
authors.forename: Xiao-Guang
authors.initials: XG
authors.lastname: Zhou
authors.forename: Xian
authors.initials: X
authors.lastname: Shen
mesh_terms: D020345:Enterocolitis, Necrotizing / Q000097:blood / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood / Q000175:diagnosis*; D008297:Male; D011228:Prealbumin / Q000032:analysis*; D012372:ROC Curve; D012720:Severity of Illness Index
chemical_list: D011228:Prealbumin