title: Echocardiographic quantification of systolic function during atrial fibrillation: probing the 'ten heart cycles' rule.
abstract: It is often difficult to provide an exact echocardiographic measure of left ventricular systolic function in patients with atrial fibrillation, partly because of the varying cycle length affecting pre and afterload and partly because of the increased heart rate often accompanying this arrhythmia. We sought to elucidate two points: whether it would be possible to correct for the cyclic variance in systolic output, and if global longitudinal strain is preferable to the left ventricular ejection fraction at evaluating systolic function during atrial fibrillation.
authors.affiliation: Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Denmark, Niels Andersens Vej 65, 2900 Hellerup, Denmark.
authors.forename: Flemming Javier
authors.initials: FJ
authors.lastname: Olsen
authors.affiliation: Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Denmark, Niels Andersens Vej 65, 2900 Hellerup, Denmark.|Institute of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Denmark.
authors.forename: Peter Godsk
authors.initials: PG
authors.lastname: Jørgensen
authors.affiliation: Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Denmark, Niels Andersens Vej 65, 2900 Hellerup, Denmark.
authors.forename: Maria
authors.initials: M
authors.lastname: Dons
authors.affiliation: Institute of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Denmark.|Department of Cardiology, Rigshospitalet, University of Copenhagen, Denmark.
authors.forename: Jesper Hastrup
authors.initials: JH
authors.lastname: Svendsen
authors.affiliation: Institute of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Denmark.|Department of Cardiology, Rigshospitalet, University of Copenhagen, Denmark.
authors.forename: Lars
authors.initials: L
authors.lastname: Køber
authors.affiliation: Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Denmark, Niels Andersens Vej 65, 2900 Hellerup, Denmark.|Institute of Clinical Medicine, Faculty of Health & Medical Sciences, University of Copenhagen, Denmark.
authors.forename: Jan Skov
authors.initials: JS
authors.lastname: Jensen
authors.affiliation: Department of Cardiology, Herlev & Gentofte Hospital, University of Copenhagen, Denmark, Niels Andersens Vej 65, 2900 Hellerup, Denmark.|Department of Medicine, Cardiovascular Medicine Division, Brigham & Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
authors.forename: Tor
authors.initials: T
authors.lastname: Biering-Sørensen
mesh_terms: D000368:Aged; D001281:Atrial Fibrillation / Q000000981:diagnostic imaging* / Q000503:physiopathology* / Q000628:therapy; D004452:Echocardiography; D005260:Female; D006801:Humans; D013318:Stroke Volume / Q000502:physiology; D013599:Systole / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology
keywords: atrial fibrillation; echocardiography; global longitudinal strain; myocardial deformation; systolic function