title: Management of an invasive and metastatic Sertoli cell tumor with associated myelotoxicosis in a dog.
abstract: We describe the surgical and post-operative management of a large, invasive, and metastatic functional Sertoli cell tumor in a 9-year-old cryptorchid male Labrador retriever dog. Despite residual disease after surgery, bone marrow recovery occurred without administration of bone marrow stimulants and serum estradiol accurately predicted tumor recurrence.
authors.affiliation: William R. Pritchard Veterinary Medical Teaching Hospital (Withers, Lawson, Burton), Department of Surgical and Radiological Sciences (Rebhun, Steffey), School of Veterinary Medicine, University of California-Davis, Davis, California, 95616, USA.
authors.forename: Sita S
authors.initials: SS
authors.lastname: Withers
authors.affiliation: William R. Pritchard Veterinary Medical Teaching Hospital (Withers, Lawson, Burton), Department of Surgical and Radiological Sciences (Rebhun, Steffey), School of Veterinary Medicine, University of California-Davis, Davis, California, 95616, USA.
authors.forename: Corinne M
authors.initials: CM
authors.lastname: Lawson
authors.affiliation: William R. Pritchard Veterinary Medical Teaching Hospital (Withers, Lawson, Burton), Department of Surgical and Radiological Sciences (Rebhun, Steffey), School of Veterinary Medicine, University of California-Davis, Davis, California, 95616, USA.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Burton
authors.affiliation: William R. Pritchard Veterinary Medical Teaching Hospital (Withers, Lawson, Burton), Department of Surgical and Radiological Sciences (Rebhun, Steffey), School of Veterinary Medicine, University of California-Davis, Davis, California, 95616, USA.
authors.forename: Robert B
authors.initials: RB
authors.lastname: Rebhun
authors.affiliation: William R. Pritchard Veterinary Medical Teaching Hospital (Withers, Lawson, Burton), Department of Surgical and Radiological Sciences (Rebhun, Steffey), School of Veterinary Medicine, University of California-Davis, Davis, California, 95616, USA.
authors.forename: Michele A
authors.initials: MA
authors.lastname: Steffey
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000473:pathology; D003456:Cryptorchidism / Q000601:surgery / Q000628:therapy / Q000662:veterinary; D004283:Dog Diseases / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D004285:Dogs; D004967:Estrogens / Q000097:blood / Q000633:toxicity; D037901:Euthanasia, Animal; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000662:veterinary; D012707:Sertoli Cell Tumor / Q000556:secondary / Q000601:surgery / Q000628:therapy / Q000662:veterinary*; D013736:Testicular Neoplasms / Q000473:pathology / Q000601:surgery / Q000628:therapy / Q000662:veterinary*
chemical_list: D004967:Estrogens