title: Whole Exome Sequencing: The Next Phase of Genetics Care.
abstract: Exome sequencing is a technique for sequencing all of the genes that code for functioning proteins in the genome. It is now being used to identify mutations in families with suspected hereditary cancer syndromes where single-gene testing or testing for a panel of genes has not been able to detect a mutation. Oncology nurses need to anticipate that more patients and families will be undergoing this testing and be prepared to explain basic concepts about this new technology.
authors.affiliation: Department of Internal Medicine and in the School of Nursing at Saint Louis University in Missouri.
authors.forename: Suzanne M
authors.identifier: 0000-0003-0919-6444
authors.initials: SM
authors.lastname: Mahon
mesh_terms: D059472:Exome; D020022:Genetic Predisposition to Disease / Q000235:genetics*; D005820:Genetic Testing / Q000379:methods*; D006801:Humans; D009369:Neoplasms / Q000235:genetics*; D009386:Neoplastic Syndromes, Hereditary / Q000235:genetics*; D009859:Oncology Nursing / Q000379:methods*; D017422:Sequence Analysis, DNA / Q000379:methods*
keywords: exome sequencing; genetic testing; genetics; hereditary cancer syndromes