title: Celiac crisis in children in Serbia.
abstract: BACKGROUND
  To assess the prevalence and risk factors of celiac crisis (CC) in children with classical celiac disease (CD).
  
  
  METHODS
  This retrospective study comprised 367 children with classical CD diagnosed from 1994 to 2015. The diagnosis of CD was based on the revised ESPGHAN criteria and CC on acute worsening and rapid progression of chronic diarrhea and vomiting followed by severe dehydration, multiple metabolic derangements and a marked decrease of body weight.
  
  
  RESULTS
  Celiac crisis was confirmed in six (1.63 %) children, five in the first and one in the second year of life. In three patients CC was precipitated by rotavirus and in one by Salmonella enteritidis infection, while in the remaining two, except for a too long-standing disease and severe malnutrition, no additional causes of CC were found.
  
  
  CONCLUSIONS
  Celiac crisis in Serbia is still-present in children exclusively below the second year of life as a spontaneous or intestinal infection precipitated complication of previously unrecognized CD.
authors.affiliation: Faculty of Medicine, University of Belgrade, Dr Subotica 9, Belgrade, 11000, Serbia. n.radlovic@beotel.net.|University Children's Hospital, Tirsova 10, Belgrade, 11000, Serbia. n.radlovic@beotel.net.|Academy of Medical Sciences of the Serbian Medical Society, Dzordza Vasingtona 19, Belgrade, 11000, Serbia. n.radlovic@beotel.net.
authors.forename: Nedeljko
authors.initials: N
authors.lastname: Radlovic
authors.affiliation: Faculty of Medicine, University of Belgrade, Dr Subotica 9, Belgrade, 11000, Serbia. zlekovic2000@yahoo.com.|University Children's Hospital, Tirsova 10, Belgrade, 11000, Serbia. zlekovic2000@yahoo.com.
authors.forename: Zoran
authors.initials: Z
authors.lastname: Lekovic
authors.affiliation: University Children's Hospital, Tirsova 10, Belgrade, 11000, Serbia. vladar@beotel.net.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Radlovic
authors.affiliation: Faculty of Medicine, University of Belgrade, Dr Subotica 9, Belgrade, 11000, Serbia. dusicasimic2@gmail.com.|University Children's Hospital, Tirsova 10, Belgrade, 11000, Serbia. dusicasimic2@gmail.com.
authors.forename: Dusica
authors.initials: D
authors.lastname: Simic
authors.affiliation: Pediatric Clinic, Clinical Centre, Zmaj Jovina 30, Kragujevac, 34000, Serbia. sibil.kg@gmail.com.
authors.forename: Biljana
authors.initials: B
authors.lastname: Vuletic
authors.affiliation: Faculty of Medicine, University of Belgrade, Dr Subotica 9, Belgrade, 11000, Serbia. sinisaducic@gmail.com.|University Children's Hospital, Tirsova 10, Belgrade, 11000, Serbia. sinisaducic@gmail.com.
authors.forename: Sinisa
authors.initials: S
authors.lastname: Ducic
authors.affiliation: Faculty of Medicine, University of Belgrade, Dr Subotica 9, Belgrade, 11000, Serbia. zstoj@sezampro.rs.|Institute of Pathology, Faculty of Medicine, University of Belgrade, Dr Subotica 1, Belgrade, 11000, Serbia. zstoj@sezampro.rs.
authors.forename: Zorica
authors.initials: Z
authors.lastname: Stojsic
mesh_terms: D000293:Adolescent; D002446:Celiac Disease / Q000175:diagnosis* / Q000178:diet therapy / Q000453:epidemiology*; D002648:Child; D002675:Child, Preschool; D003937:Diagnosis, Differential; D055050:Diet, Gluten-Free; D018450:Disease Progression; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D012189:Retrospective Studies; D055771:Serbia / Q000453:epidemiology