title: Ultrasound prenatal diagnosis of congenital primary aphakia: case report.
abstract: BACKGROUND
  the ultrasound prenatal diagnosis of aphakia is a difficult diagnosis and often requires a genetic study of the karyotype.
  
  
  METHODS
  we present a rare case of prenatal bilateral aphakia, confirmed after bird. The patient was observed by ultrasound during the 23rd week of pregnancy. Through transabdominal ultrasound the lens could not be visualized bilaterally. The remaining anathomy, explorable by ultrasound, was still regular. When aphakia is suspected, genetic counseling is essential.
  
  
  CONCLUSIONS
  a differential diagnosis between aphakia and anophtalmia is necessary. A TORCH complex evaluation can be useful. Amniocentesis is always required.
authors.affiliation: Department of Ginecological-Obstetrical Sciences and Urological Sciences, "Sapienza" University of Rome, Rome, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Di Meglio
authors.affiliation: Department of Woman, Child and General and Specialistics Surgery, II University of Naples, Naples, Italy.
authors.forename: Carmine
authors.initials: C
authors.lastname: Vascone
authors.affiliation: Clinical Department of Ginecology and Obstetrics of Physiopathology Reproduction, "Federico II" University of Naples, Naples, Italy.
authors.forename: Letizia
authors.initials: L
authors.lastname: Di Meglio
authors.affiliation: Clinical Department for the Woman's Health and Protection, Newborning life, Child and Adolescent. Catholic University of "Sacro Cuore", "Agostino Gemelli" Polyclinic of Rome, Rome, Italy.
authors.forename: Luigi Carlo Lo
authors.initials: LC
authors.lastname: Turco
authors.affiliation: Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
authors.forename: Salvatore Giovanni
authors.initials: SG
authors.lastname: Vitale
authors.affiliation: Department of Gynecologic Ultrasound Imaging, Altamedica Fetal Maternal Medical Centre, Rome, Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Cignini
authors.affiliation: Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
authors.forename: Gaetano
authors.initials: G
authors.lastname: Valenti
authors.affiliation: Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
authors.forename: Ferdinando Antonio
authors.initials: FA
authors.lastname: Gulino
authors.affiliation: Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
authors.forename: Agnese Maria Chiara
authors.initials: AM
authors.lastname: Rapisarda
authors.affiliation: Department of General Surgery and Medical Surgical Specialties, University of Catania, Catania, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Cianci
keywords: anterior segment of the eye; congenital aphakia; lens; prenatal diagnosis; ultrasound