title: Prevalence of hyperuricemia among Beijing post-menopausal women in 10 years.
abstract: OBJECTIVE
  The objective of this study was to explore the trend and risk factors of the prevalence of hyperuricemia among post-menopausal women in Beijing over a ten years period.
  
  
  METHODS
  This research was based on two cross-sectional surveys in post-menopausal women in Beijing. A total of 1881 post-menopausal women were included. Subjects answered a questionnaire and underwent a physical examination and blood test. Serum uric acid >357 μmol/L was diagnosed as hyperuricemia, and another diagnosis criterion (serum uric acid >416 μmol/L) was applied in these women.
  
  
  RESULTS
  Serum uric acid levels and hyperuricemia prevalence increased remarkably in the 10-year period. The prevalence of hyperuricemia increased more than 2-fold after being adjusted by age. Multivariate logistic regression models revealed hyperuricemia associated with age, education level, urban residents, alcohol consumption, hypertension, obesity, and dyslipidemia. With the increasing number of traditional cardiovascular risk factors (including hypertension, obesity, diabetes, and dyslipidemia), the risk of hyperuricemia increased significantly, and the accumulative effect of the factors on the risk of hyperuricemia was determined.
  
  
  CONCLUSIONS
  The prevalence of hyperuricemia was high and exhibited a remarkable, increasing trend in Beijing community-based, post-menopausal women. Better management of relative factors could help to prevent further increases in the burden of hyperuricemia in post-menopausal women in this region.
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China.
authors.forename: Shaochen
authors.initials: S
authors.lastname: Guan
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Tang
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China. Electronic address: xhfang163@163.com.
authors.forename: Xianghua
authors.initials: X
authors.lastname: Fang
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China.
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China.
authors.forename: Hongjun
authors.initials: H
authors.lastname: Liu
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China.
authors.forename: Chunxiu
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China; Key Laboratory for Neurodegenerative Disease of Ministry of Education, China.
authors.forename: Chengbei
authors.initials: C
authors.lastname: Hou
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000428:Alcohol Drinking / Q000453:epidemiology; D000068476:Beijing / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D033461:Hyperuricemia / Q000097:blood / Q000208:ethnology*; D016015:Logistic Models; D008875:Middle Aged; D009765:Obesity / Q000453:epidemiology; D017698:Postmenopause / Q000097:blood / Q000208:ethnology*; D015995:Prevalence; D012111:Residence Characteristics; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D014527:Uric Acid / Q000097:blood*
chemical_list: D014527:Uric Acid
keywords: Cross-sectional study; Hyperuricemia; Post-menopausal; Prevalence; Risk factors