title: [Xenon: From rare gaz to doping product].
abstract: Doping is defined as the use of processes or substances to artificially increase physical or mental performance. Xenon is a noble gas used as an anesthetic and recently as a doping agent. Xenon is neuroprotective as an antagonist of NMDA glutamate receptors. Xenon stimulates the synthesis of erythropoietin (EPO) by increase of hypoxia inducible factor (HIF). Xenon would be a new doping product, maintaining doping methods ahead of detection.
authors.affiliation: CHU de Rennes, CHU Pontchaillou, laboratoire de toxicologie biologique et médico-légale, 35033 Rennes, France; Université Rennes 1, faculté de pharmacie, 35043 Rennes, France.
authors.forename: Camille
authors.initials: C
authors.lastname: Tassel
authors.affiliation: CHU de Rennes, CHU Pontchaillou, laboratoire de toxicologie biologique et médico-légale, 35033 Rennes, France; Université Rennes 1, faculté de pharmacie, 35043 Rennes, France; CHU de Rennes, pôle pharmacie, 35033 Rennes, France.
authors.forename: Brendan
authors.initials: B
authors.lastname: Le Daré
authors.affiliation: CHU de Rennes, CHU Pontchaillou, laboratoire de toxicologie biologique et médico-légale, 35033 Rennes, France; Université Rennes 1, faculté de pharmacie, 35043 Rennes, France; Inserm, UMR991 « Foie, métabolismes et cancer », 35043 Rennes, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Morel
authors.affiliation: CHU de Rennes, CHU Pontchaillou, laboratoire de toxicologie biologique et médico-légale, 35033 Rennes, France; Université Rennes 1, faculté de pharmacie, 35043 Rennes, France; Inserm, UMR991 « Foie, métabolismes et cancer », 35043 Rennes, France. Electronic address: thomas.gicquel@chu-rennes.fr.
authors.forename: Thomas
authors.initials: T
authors.lastname: Gicquel
mesh_terms: D004300:Doping in Sports / Q000517:prevention & control; D006801:Humans; D014978:Xenon / Q000494:pharmacology
chemical_list: D014978:Xenon