title: Delayed sequence intubation: is it ready for prime time?
abstract: Clinical question Does delayed sequence intubation (DSI) improve preoxygenation and safety when intubating otherwise uncooperative patients? Article chosen Weingart SD, Trueger S, Wong N, et al. Delayed sequence intubation: a prospective observational study. Ann Emerg Med 2015;65(4):349-55. doi:10.1016/j.annemergmed.2014.09.025 OBJECTIVE: To investigate whether the administration of ketamine 3 minutes prior to the administration of a muscle relaxant allows for optimal preoxygenation in uncooperative patients undergoing intubation.
authors.affiliation: *Emergency Department,Vancouver General Hospital,Vancouver,BC.
authors.forename: John A
authors.initials: JA
authors.lastname: Taylor
authors.affiliation: *Emergency Department,Vancouver General Hospital,Vancouver,BC.
authors.forename: Corinne Michele
authors.initials: CM
authors.lastname: Hohl
mesh_terms: D000328:Adult; D000778:Anesthetics, Dissociative / Q000008:administration & dosage; D015331:Cohort Studies; D016292:Procedural Sedation / Q000379:methods; D003422:Critical Care / Q000379:methods; D004334:Drug Administration Schedule; D005260:Female; D006801:Humans; D007442:Intubation, Intratracheal / Q000379:methods*; D007649:Ketamine / Q000008:administration & dosage*; D008297:Male; D009125:Muscle Relaxants, Central / Q000008:administration & dosage*; D010101:Oxygen Consumption / Q000502:physiology*; D010349:Patient Compliance; D011446:Prospective Studies; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000778:Anesthetics, Dissociative; D009125:Muscle Relaxants, Central; D007649:Ketamine
keywords: delayed sequence intubation; intubation; ketamine; sedation