title: Cardiorespiratory synchronism in estimation of regulatory and adaptive organism status.
abstract: The proposed method of quantitative estimation of regulatory and adaptive status (RAS) of human organism is based on complex responses of two major vegetative functions - breath and heart rates under organism exposure to a number of factors and diseases. It has been evidenced that during the follicular menstruation stage and during optimum readiness of female organism for childbirth RAS increases, however, stress impact can also cause RAS set off to decrease. Likewise, the possibility of quantitative organism stress resistance estimation is also presented. Under some pathological conditions (myocardial infarction, hypo-and hyperthyroidism, diabetes type 2), RAS goes down, and the degree of its restoration depends on the attained therapy effect. It is shown that RAS dynamics provides an innovative methodological approach to medication efficiency estimation based on its influence not only on the body organ or target function, but also on adaptive abilities of the organism.
authors.affiliation: 1 Normal Physiology Department, Kuban State Medical University, Sedin Street, 4, Krasnodar 350063, Russia.
authors.forename: Vladimir M
authors.initials: VM
authors.lastname: Pokrovskii
authors.affiliation: 1 Normal Physiology Department, Kuban State Medical University, Sedin Street, 4, Krasnodar 350063, Russia.
authors.forename: Lily V
authors.initials: LV
authors.lastname: Polischuk
mesh_terms: D000222:Adaptation, Physiological / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D005260:Female; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D011660:Pulmonary Heart Disease / Q000175:diagnosis* / Q000503:physiopathology*; D012119:Respiration; D055815:Young Adult
keywords: Regulatory and adaptive status; quantitative estimation of regulatory and adaptive organism abilities; stress resistance