title: Update: Interim Guidelines for Health Care Providers Caring for Infants and Children with Possible Zika Virus Infection--United States, February 2016.
abstract: CDC has updated its interim guidelines for U.S. health care providers caring for infants born to mothers who traveled to or resided in areas with Zika virus transmission during pregnancy and expanded guidelines to include infants and children with possible acute Zika virus disease. This update contains a new recommendation for routine care for infants born to mothers who traveled to or resided in areas with Zika virus transmission during pregnancy but did not receive Zika virus testing, when the infant has a normal head circumference, normal prenatal and postnatal ultrasounds (if performed), and normal physical examination. Acute Zika virus disease should be suspected in an infant or child aged <18 years who 1) traveled to or resided in an affected area within the past 2 weeks and 2) has ≥2 of the following manifestations: fever, rash, conjunctivitis, or arthralgia. Because maternal-infant transmission of Zika virus during delivery is possible, acute Zika virus disease should also be suspected in an infant during the first 2 weeks of life 1) whose mother traveled to or resided in an affected area within 2 weeks of delivery and 2) who has ≥2 of the following manifestations: fever, rash, conjunctivitis, or arthralgia. Evidence suggests that Zika virus illness in children is usually mild. As an arboviral disease, Zika virus disease is nationally notifiable. Health care providers should report suspected cases of Zika virus disease to their local, state, or territorial health departments to arrange testing and so that action can be taken to reduce the risk for local Zika virus transmission. As new information becomes available, these guidelines will be updated: http://www.cdc.gov/zika/.
authors.forename: Katherine E
authors.initials: KE
authors.lastname: Fleming-Dutra
authors.forename: Jennifer M
authors.initials: JM
authors.lastname: Nelson
authors.forename: Marc
authors.initials: M
authors.lastname: Fischer
authors.forename: J Erin
authors.initials: JE
authors.lastname: Staples
authors.forename: Mateusz P
authors.initials: MP
authors.lastname: Karwowski
authors.forename: Paul
authors.initials: P
authors.lastname: Mead
authors.forename: Julie
authors.initials: J
authors.lastname: Villanueva
authors.forename: Christina M
authors.initials: CM
authors.lastname: Renquist
authors.forename: Anna A
authors.initials: AA
authors.lastname: Minta
authors.forename: Denise J
authors.initials: DJ
authors.lastname: Jamieson
authors.forename: Margaret A
authors.initials: MA
authors.lastname: Honein
authors.forename: Cynthia A
authors.initials: CA
authors.lastname: Moore
authors.forename: Sonja A
authors.initials: SA
authors.lastname: Rasmussen
mesh_terms: D000293:Adolescent; D018771:Arthralgia / Q000209:etiology; D001942:Breast Feeding; D002487:Centers for Disease Control and Prevention, U.S.; D002648:Child; D002675:Child, Preschool; D003231:Conjunctivitis / Q000209:etiology; D003937:Diagnosis, Differential; D005076:Exanthema / Q000209:etiology; D005260:Female; D005334:Fever / Q000209:etiology; D006282:Health Personnel; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000517:prevention & control; D014195:Travel; D014481:United States; D000071243:Zika Virus Infection / Q000151:congenital / Q000175:diagnosis* / Q000628:therapy*