title: Impact of age on transcatheter aortic valve implantation outcomes: a comparison of patients aged ≤ 80 years versus patients > 80 years.
abstract: OBJECTIVE
  To investigate the procedural outcomes and the long-term survival of patients undergoing transcatheter aortic valve implantation (TAVI) and compare study results of patients ≤ 80 years and patients > 80 years old.
  
  
  METHODS
  A total of 240 patients treated with TAVI were divided into two groups according to age ≤ 80 years (n = 105; 43.8%) and > 80 years (n = 135; 56.2%). The baseline characteristics and the procedural outcomes were compared between these two groups of patients.
  
  
  RESULTS
  With the exception of peripheral artery disease and hypercholesterolemia, which were more frequently observed in the older age group, baseline characteristics were comparable between groups. Complication rates did not differ significantly between patients ≤ 80 years and patients > 80 years. There were no differences in 30-day mortality rates between patients aged ≤ 80 years and patients > 80 years old (9.5% vs. 7.4%, respectively; P = 0.557). After a median follow-up of 28 months (interquartile range: 16-42 months), 50 (47.6%) patients aged ≤ 80 years died compared to 57 (42%) deaths in the group of patients > 80 years old (P = 0.404).
  
  
  CONCLUSIONS
  The results of the present single center study showed that age did not significantly impact the outcomes of TAVI.
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Frank
authors.initials: F
authors.lastname: van der Kley
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Philippe J
authors.initials: PJ
authors.lastname: van Rosendael
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Spyridon
authors.initials: S
authors.lastname: Katsanos
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Vasileios
authors.initials: V
authors.lastname: Kamperidis
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Nina A
authors.initials: NA
authors.lastname: Marsan
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Karalis
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Arend
authors.initials: A
authors.lastname: de Weger
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Meindert
authors.initials: M
authors.lastname: Palmen
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Jeroen J
authors.initials: JJ
authors.lastname: Bax
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Schalij
authors.affiliation: Heart Lung Center, Leiden University Medical Center, Leiden, the Netherlands.
authors.forename: Victoria
authors.initials: V
authors.lastname: Delgado
keywords: Age; Survival rate; Transcatheter aortic valve implantation