title: Cyclization of Alkyne-Azide with Isonitrile/CO via Self-Relay Rhodium Catalysis.
abstract: A self-relay rhodium(I)-catalyzed cyclization of alkyne-azides with two σ-donor/π-acceptor ligands (isonitriles and CO) to form sequentially multiple-fused heterocycle systems via tandem nitrene transformation and aza-Pauson-Khand cyclization has been developed. In this approach, an intriguing chemoselective insertion process of isonitriles superior to CO was observed. This reaction provides an alternative strategy to synthesize functionalized pyrrolo[2,3-b]indole scaffolds.
authors.affiliation: Department of Applied Chemistry, China Agricultural University , Beijing 100193, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Applied Chemistry, China Agricultural University , Beijing 100193, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Xiao
authors.affiliation: Department of Applied Chemistry, China Agricultural University , Beijing 100193, China.
authors.forename: Baoliang
authors.initials: B
authors.lastname: Huang
authors.affiliation: Department of Applied Chemistry, China Agricultural University , Beijing 100193, China.
authors.forename: Jincheng
authors.initials: J
authors.lastname: Hu
authors.affiliation: Department of Applied Chemistry, China Agricultural University , Beijing 100193, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Fu
authors.affiliation: Department of Applied Chemistry, China Agricultural University , Beijing 100193, China.
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Zhang