title: Relationship between white matter pathology and performance on the General Movement Assessment and the Test of Infant Motor Performance in very preterm infants.
abstract: BACKGROUND
  Cerebral Magnetic Resonance Imaging, the General Movement Assessment, and the Test of Infant Motor Performance are all tools that can predict neurodevelopmental outcome in preterm infants. However, how these tests relate to each other is unclear.
  
  
  OBJECTIVE
  To examine the relationship between cerebral Magnetic Resonance Imaging measured at term age, and the General Movement Assessment and Test of Infant Motor Performance measured at 10-15 weeks post-term age.
  
  
  METHODS
  Prospectively collected data in a sample of very preterm infants.
  
  
  METHODS
  Fifty-three infants (23 female, 30 male) with a median gestational age of 28 weeks (range: 23-30 weeks) and a median birth weight of 1000 g (range: 515-1465 g).
  
  
  METHODS
  Test of Infant Motor Performance, General Movement Assessment.
  
  
  RESULTS
  Infants with abnormal white matter were significantly more likely to have both abnormal general movements (p=0.01) and abnormal Test of Infant Motor Performance scores (p=0.001). Infants with abnormal general movements were significantly more likely to have lower Test of Infant Motor Performance Scores (p=0.01).
  
  
  CONCLUSIONS
  Abnormal white matter is related to motor deviations as measured by the General Movement Assessment and the Test of Infant Motor Performance as early as 3 months post-term age in a cohort of preterm infants.
authors.affiliation: Department of Therapy Services, University of Chicago Medicine, 5841 S. Maryland Ave, Chicago, IL 60637, USA. Electronic address: colleen.peyton@uchospitals.edu.
authors.forename: Colleen
authors.initials: C
authors.lastname: Peyton
authors.affiliation: Department of Pediatrics, University of Chicago Medicine, Comer Children's Hospital, Sections of Neonatology, Developmental Pediatrics, 5841 S. Maryland Ave, Chicago, IL 60637, USA; Kennedy Research Center on Intellectual and Neurodevelopmental Disabilities, 5841 S. Maryland Ave, Chicago, IL 60637, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Yang
authors.affiliation: Department of Health Studies, University of Chicago Medicine, 5841 S. Maryland Ave, Chicago, IL 60637, USA.
authors.forename: Masha
authors.initials: M
authors.lastname: Kocherginsky
authors.affiliation: Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Olav Kyrres gt. 11, 7491 Trondheim, Norway; Clinics of Clinical Services, St. Olav University Hospital, Box 3250, Sluppen, 7006 Trondheim, Norway.
authors.forename: Lars
authors.initials: L
authors.lastname: Adde
authors.affiliation: Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Olav Kyrres gt. 11, 7491 Trondheim, Norway; Clinics of Clinical Services, St. Olav University Hospital, Box 3250, Sluppen, 7006 Trondheim, Norway.
authors.forename: Toril
authors.initials: T
authors.lastname: Fjørtoft
authors.affiliation: Department of Laboratory Medicine, Children's and Women's Health, Norwegian University of Science and Technology, Olav Kyrres gt. 11, 7491 Trondheim, Norway; Department of Pediatrics, St. Olav University Hospital, Box 3250, Sluppen, 7006 Trondheim, Norway.
authors.forename: Ragnhild
authors.initials: R
authors.lastname: Støen
authors.affiliation: Division of Neonatology, University of Groningen, 9712 CP Groningen, Netherlands.
authors.forename: Arend F
authors.initials: AF
authors.lastname: Bos
authors.affiliation: Institute of Physiology, Center for Physiological Medicine, Medical University of Graz, Universitätsstraße 15, 8010 Graz, Austria.
authors.forename: Christa
authors.initials: C
authors.lastname: Einspieler
authors.affiliation: Department of Pediatrics, University of Chicago Medicine, Comer Children's Hospital, Sections of Neonatology, Developmental Pediatrics, 5841 S. Maryland Ave, Chicago, IL 60637, USA; Kennedy Research Center on Intellectual and Neurodevelopmental Disabilities, 5841 S. Maryland Ave, Chicago, IL 60637, USA.
authors.forename: Michael D
authors.initials: MD
authors.lastname: Schreiber
authors.affiliation: Department of Pediatrics, University of Chicago Medicine, Comer Children's Hospital, Sections of Neonatology, Developmental Pediatrics, 5841 S. Maryland Ave, Chicago, IL 60637, USA; Kennedy Research Center on Intellectual and Neurodevelopmental Disabilities, 5841 S. Maryland Ave, Chicago, IL 60637, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Msall
mesh_terms: D005260:Female; D006801:Humans; D062071:Infant, Extremely Premature / Q000502:physiology*; D007231:Infant, Newborn; D008297:Male; D009068:Movement; D066127:White Matter / Q000473:pathology*
keywords: General movements; MRI; Test of Infant Motor Performance