title: Cardiac Involvement in Peripheral Neuropathies.
abstract: Cardiac autonomic neuropathy (CAN) is the least recognized and understood complication of peripheral neuropathy. However, because of its potential adverse effects including sudden death, CAN is one of the most important forms of autonomic neuropathies. CAN presents with different clinical manifestations including postural hypotension, exercise intolerance, fluctuation of blood pressure and heart rate, arrhythmia, and increased risk of myocardial infarction. In this article, the prevalence, clinical presentations, and management of cardiac involvement in certain peripheral neuropathies, including diabetic neuropathy, Guillain-Barré syndrome, chronic inflammatory polyneuropathy, human immunodeficiency virus-associated neuropathy, hereditary neuropathies, and amyloid neuropathy are examined in detail.
authors.affiliation: *Department of Medicine, MDA/ALS Clinic at Carilion Clinic, Roanoke, VA; Virginia Tech Carilion School of Medicine and Research Institute; and †Department of Medicine, Carilion Clinic Heart Rhythm Services; Virginia Tech Carilion School of Medicine and Research Institute.
authors.forename: Ahmet Z
authors.initials: AZ
authors.lastname: Burakgazi
authors.forename: Soufian
authors.initials: S
authors.lastname: AlMahameed
mesh_terms: D006331:Heart Diseases / Q000150:complications*; D006801:Humans; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000175:diagnosis / Q000628:therapy