title: The synthesis of pillar[5]arene functionalized graphene as a fluorescent probe for paraquat in living cells and mice.
abstract: As complex organisms vary in vivo, it remains a challenging task to get fluorescence 'turn on' imaging for special targets. To address this task, we have adopted a new strategy of inducing pillararene based host-guest interactions onto biocompatible graphene. By means of fluorescence competition displacement, hydrazino-pillar[5]arene modified graphene has been synthesized and provided as a 'turn on' probe for paraquat through monitoring of the fluorescence signal both in living cells and mice.
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. lhbing@mail.ccnu.edu.cn.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Mao
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. lhbing@mail.ccnu.edu.cn.
authors.forename: Ting
authors.initials: T
authors.lastname: Liu
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. lhbing@mail.ccnu.edu.cn.
authors.forename: Jiahai
authors.initials: J
authors.lastname: Bi
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. lhbing@mail.ccnu.edu.cn.
authors.forename: Li
authors.initials: L
authors.lastname: Luo
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. lhbing@mail.ccnu.edu.cn.
authors.forename: Demei
authors.initials: D
authors.lastname: Tian
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology (CCNU), Ministry of Education, College of Chemistry, Central China Normal University, Wuhan 430079, P. R. China. lhbing@mail.ccnu.edu.cn.
authors.forename: Haibing
authors.initials: H
authors.lastname: Li
mesh_terms: D000818:Animals; D047250:Calixarenes; D005456:Fluorescent Dyes / Q000737:chemistry*; D006108:Graphite / Q000737:chemistry*; D051379:Mice; D010269:Paraquat / Q000032:analysis*; D000644:Quaternary Ammonium Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D000644:Quaternary Ammonium Compounds; C570642:pillar(5)arene; D047250:Calixarenes; D006108:Graphite; D010269:Paraquat