title: Anatomic Derkay Score Is Associated with Voice Handicap in Laryngeal Papillomatosis in Adults.
abstract: OBJECTIVE
  The Derkay staging system quantifies recurrent respiratory papillomatosis (RRP) severity based on involvement of laryngeal structures. Despite its broad use in the laryngology literature, the association between Derkay score and voice-related quality of life has not previously been studied. It is hypothesized that Derkay score positively correlates with the Voice Handicap Index-10 (VHI-10).
  
  
  METHODS
  Case series with chart review.
  
  
  METHODS
  Tertiary medical center.
  
  
  METHODS
  Forty-six adult RRP patients treated from 2007 to 2013 at a tertiary medical center were included. Anatomic Derkay scores at the time of each RRP procedure were calculated. VHI-10 scores obtained within 30 days preceding the procedures were used to assess for correlation between Derkay staging system and VHI-10.
  
  
  RESULTS
  Ninety-three procedures performed on 46 patients met inclusion criteria. Mean Derkay score was 11.9 (range, 2-28), and mean VHI-10 was 18.0 (range, 0-40). There was a significant positive correlation between Derkay score and VHI-10 (Spearman coefficient r = 0.42, P < .0001).
  
  
  CONCLUSIONS
  The anatomic burden of RRP as assessed by Derkay staging system is positively correlated with voice-related quality of life as quantified by the VHI-10.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA Department of Otolaryngology-Head and Neck Surgery, University of Michigan Medical School, Ann Arbor, Michigan, USA rkupfer@med.umich.edu.
authors.forename: Robbi A
authors.initials: RA
authors.lastname: Kupfer
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA Department of Otolaryngology, Dişkapi Yildirim Beyazit Training and Research Hospital, Ankara, Turkey.
authors.forename: Emel
authors.initials: E
authors.lastname: Çadalli Tatar
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA Department of Otolaryngology-Head and Neck Surgery, University of Arizona, Tucson, Arizona, USA.
authors.forename: Jonnae O
authors.initials: JO
authors.lastname: Barry
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University, Bethesda, Maryland, USA.
authors.forename: Clint T
authors.initials: CT
authors.lastname: Allen
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, University of Washington School of Medicine, Seattle, Washington, USA.
authors.forename: Albert L
authors.initials: AL
authors.lastname: Merati
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D030361:Papillomavirus Infections / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D011788:Quality of Life; D012141:Respiratory Tract Infections / Q000473:pathology / Q000503:physiopathology* / Q000601:surgery*; D012189:Retrospective Studies; D012720:Severity of Illness Index; D014833:Voice Quality
keywords: Derkay score; Voice Handicap Index–10; laryngeal papilloma; recurrent respiratory papillomatosis; voice-related quality of life