title: [Influencing factors of orthostatism brachial-ankle pulse wave velocity and ankle brachial index in the elderly].
abstract: OBJECTIVE
  To investigate the distribution and influencing factors of orthostatism brachial-ankle pulse wave velocity(baPWV) and ankle brachial index(ABI) in the elderly.
  
  
  METHODS
  Participants were selected with random sampling from ≥60 years old retired workers, who underwent 2010 to 2011 health check-up in the Tangshan Kailuan Hospital, Kailuan Linxi Hospital, Kailuan Zhaogezhuang Hospital. Multivariate linear regression analysis was used to analyze the influencing factors of orthostatism and supine baPWV and ABI in the elderly.
  
  
  RESULTS
  (1) A total of 2 464 participants were included, and 1 601 participants (1 065 males(66.5%) and (67.5±6.1) years old) with integral data were analyzed. Orthostatism baPWV was (3 885.4±1 503.5)cm/s and Supine baPWV was (1 761.2±371.4)cm/s.Orthostatism ABI was 1.54±0.21 and supine ABI was 1.10±0.12. Orthostatism baPWV increased with increasing age, while orthostatism ABI decreased with aging(trend test, both P<0.01)in <65, 65-69, 70-74, and ≥75 years old participants.(2) Multiple linear regression analysis showed that the age(β=0.19, P<0.01), lower limbs orthostatism systolic blood pressure(β=0.18, P<0.01), lower limbs supine systolic blood pressure (β=0.14, P<0.01), orthostatism heart rate (β=0.30, P<0.01), supine heart rate (β=0.23, P<0.01), body mass index (β=-0.18, P<0.01) were associated with orthostatism baPWV, and female(β=-0.055, P=0.01), upper limb orthostatism systolic blood pressure (β=-0.834, P<0.01), lower limbs orthostatism systolic blood pressure (β=0.708, P<0.01), lower limbs supine systolic blood pressure (β=0.099, P<0.01) and fasting blood glucose(β=-0.085, P<0.01) were associated with orthostatism ABI.
  
  
  CONCLUSIONS
  Orthostatism baPWV and ABI were significantly higher than those of supine's. Age, lower limbs orthostatism and supine systolic blood pressure, orthostatism and supine heart rate, body mass index were associated with orthostatism baPWV. Female, upper limb orthostatism systolic blood pressure, lower limbs orthostatism, supine systolic blood pressure and fasting blood glucose were associated with orthostatism ABI in the elderly.
authors.affiliation: Department of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan 063000, China.
authors.forename: X M
authors.initials: XM
authors.lastname: Zheng
authors.forename: Z F
authors.initials: ZF
authors.lastname: Li
authors.forename: Y T
authors.initials: YT
authors.lastname: Wu
authors.forename: X H
authors.initials: XH
authors.lastname: Zhao
authors.forename: H Y
authors.initials: HY
authors.lastname: Zhao
authors.forename: C
authors.initials: C
authors.lastname: Jin
authors.forename: H M
authors.initials: HM
authors.lastname: Liu
authors.forename: S H
authors.initials: SH
authors.lastname: Chen
authors.forename: S S
authors.initials: SS
authors.lastname: An
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.forename: S L
authors.initials: SL
authors.lastname: Wu
mesh_terms: D000842:Ankle; D055109:Ankle Brachial Index; D001783:Blood Flow Velocity; D001794:Blood Pressure; D015992:Body Mass Index; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011673:Pulsatile Flow; D063177:Pulse Wave Analysis; D012044:Regression Analysis