title: Acute Pulmonary Embolism: With an Emphasis on an Interventional Approach.
abstract: Compared with recent advances in treatment of serious cardiovascular diseases, such as myocardial infarction and stroke, the treatment and outcome of acute pulmonary embolism (PE) have remained relatively unchanged over the last few decades. This has prompted several experts to call for the formation of multidisciplinary PE response teams with a more proactive approach to the treatment of PE. In the current document, we discuss the formation of such teams and describe the available treatment options beyond anticoagulation, with a focus on the interventional approach. Acknowledging the paucity of data to support widespread adoption of such techniques, we call for the collection of outcomes data in multicenter registries and support for randomized trials to evaluate interventional treatments in patients with high-risk PE.
authors.affiliation: Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Wissam A
authors.initials: WA
authors.lastname: Jaber
authors.affiliation: Vanderbilt Heart and Vascular Institute, Nashville, Tennessee.
authors.forename: Pete P
authors.initials: PP
authors.lastname: Fong
authors.affiliation: Division of Cardiology, Shari Zadek Medical Center, Jerusalem, Israel.
authors.forename: Giora
authors.initials: G
authors.lastname: Weisz
authors.affiliation: Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Omar
authors.initials: O
authors.lastname: Lattouf
authors.affiliation: Ochsner Medical Center, New Orleans, Louisiana.
authors.forename: James
authors.initials: J
authors.lastname: Jenkins
authors.affiliation: Section of Vascular Medicine, & Intervention, Division of Cardiology, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Rosenfield
authors.affiliation: Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia. Electronic address: srab@emory.edu.
authors.forename: Tanveer
authors.initials: T
authors.lastname: Rab
authors.affiliation: Structural and Valvular Heart Disease Program, Ochsner Medical Center, New Orleans, Louisiana.
authors.forename: Stephen
authors.initials: S
authors.lastname: Ramee
mesh_terms: D000208:Acute Disease; D000925:Anticoagulants / Q000627:therapeutic use*; D019468:Disease Management; D017128:Embolectomy / Q000379:methods*; D006801:Humans; D011655:Pulmonary Embolism / Q000628:therapy*; D012042:Registries; D015912:Thrombolytic Therapy / Q000379:methods*
chemical_list: D000925:Anticoagulants
keywords: embolectomy; fibrinolysis; interventional management; pulmonary artery