title: STAMPing at the crossroads of normal physiology and disease states.
abstract: The six transmembrane protein of prostate (STAMP) proteins, also known as six transmembrane epithelial antigen of prostate (STEAPs), comprises three members: STAMP1-3. Their expression is regulated by a variety of stimuli, including hormones and cytokines, in varied settings and tissues with important roles in secretion and cell differentiation. In addition, they are implicated in metabolic and inflammatory diseases and cancer. Here, we review the current knowledge on the role of STAMPs in both physiological and pathological states.
authors.affiliation: Department of Biosciences, University of Oslo, Oslo, Norway.
authors.forename: Jørgen
authors.initials: J
authors.lastname: Sikkeland
authors.affiliation: Department of Biosciences, University of Oslo, Oslo, Norway.
authors.forename: Xia
authors.initials: X
authors.lastname: Sheng
authors.affiliation: Department of Biosciences, University of Oslo, Oslo, Norway.
authors.forename: Yang
authors.initials: Y
authors.lastname: Jin
authors.affiliation: Department of Biosciences, University of Oslo, Oslo, Norway; Institute for Cancer Genetics and Informatics, Oslo University Hospital, Oslo, Norway. Electronic address: fahris@ibv.uio.no.
authors.forename: Fahri
authors.initials: F
authors.lastname: Saatcioglu
mesh_terms: D000818:Animals; D018797:Cell Cycle Proteins; D002454:Cell Differentiation; D005786:Gene Expression Regulation; D006801:Humans; D007249:Inflammation / Q000378:metabolism; D008565:Membrane Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D008659:Metabolic Diseases / Q000378:metabolism; D009363:Neoplasm Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D009369:Neoplasms / Q000378:metabolism; D015513:Oncogene Proteins / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D010088:Oxidoreductases / Q000737:chemistry / Q000235:genetics / Q000378:metabolism*; D014018:Tissue Distribution
chemical_list: D018797:Cell Cycle Proteins; D008565:Membrane Proteins; D009363:Neoplasm Proteins; D015513:Oncogene Proteins; D010088:Oxidoreductases; C486677:STEAP3 protein, human; C467741:STEAP2 protein, human; C503310:STEAP4 protein, human
keywords: Inflammation; Ironreductase; Metabolism; Prostate cancer; STAMP; STEAP