title: Bisdioxycalamenene: A Bis-Sesquiterpene from the Soft Coral Rhytisma fulvum fulvum.
abstract: A dichloromethane extract of the soft coral Rhytisma fulvum fulvum collected in Madagascar afforded a novel compound possessing an unprecedented pentacyclic skeleton, bisdioxycalamenene (1), as well as seven known sesquiterpenes. The structures of the compounds were elucidated using 1D and 2D NMR techniques, as well as high-resolution mass spectrometry. The absolute configuration of 1 was determined using X-ray diffraction analysis and anomalous dispersion effects. The structure elucidation and a possible biogenesis of the compound are discussed.
authors.affiliation: School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel. yuvaltri@mail.tau.ac.il.
authors.forename: Yuval J
authors.initials: YJ
authors.lastname: Trifman
authors.affiliation: Laboratory of Chemistry of Natural Substances and Food Sciences, Faculty of Science and Technology, University of Reunion Island, 15 Avenue René Cassin, CS 92003, 97744 Saint-Denis Cedex 9, La Reunion, France. maurice.aknin@univ-reunion.fr.
authors.forename: Maurice
authors.initials: M
authors.lastname: Aknin
authors.affiliation: Laboratory of Chemistry of Natural Substances and Food Sciences, Faculty of Science and Technology, University of Reunion Island, 15 Avenue René Cassin, CS 92003, 97744 Saint-Denis Cedex 9, La Reunion, France. anne.bialecki@univ-reunion.fr.
authors.forename: Anne
authors.initials: A
authors.lastname: Gauvin-Bialecki
authors.affiliation: Department of Zoology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978, Israel. yehudab@tauex.tau.ac.il.
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Benayahu
authors.affiliation: School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel. carmeli@post.tau.ac.il.
authors.forename: Shmuel
authors.initials: S
authors.lastname: Carmeli
authors.affiliation: School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Tel Aviv 69978, Israel. kashman@post.tau.ac.il.
authors.forename: Yoel
authors.initials: Y
authors.lastname: Kashman
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry*; D008270:Madagascar; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*; D014961:X-Ray Diffraction
chemical_list: D012717:Sesquiterpenes; D013729:Terpenes
keywords: Rhytisma fulvum fulvum; bis-sesquiterpene; bisdioxycalamenene; soft coral