title: Echocardiographic and Surgical Correlation of Coronary Artery Patterns in Transposition of the Great Arteries.
abstract: OBJECTIVE
  Determine the accuracy of echocardiography to diagnose coronary anatomy in transposition of the great arteries and to evaluate the effect of accuracy on surgical outcomes and changes in accuracy over time.
  
  
  METHODS
  Retrospective chart review of neonates admitted February 1999 to March 2013 with transposition. Coronary pattern from the preoperative echocardiogram and operative reports were collected and compared with determine diagnostic accuracy. Coronary patterns were further confirmed by intraoperative images taken during surgery.
  
  
  METHODS
  Tertiary care children's hospital.
  
  
  METHODS
  Neonates with transposition of the great arteries and planned arterial switch operation with an echo and operative report or image describing the coronaries.
  
  
  METHODS
  Not applicable.
  
  
  METHODS
  Accuracy of echocardiography to diagnose coronary anatomy in transposition, and to identify factors related to correct diagnosis.
  
  
  RESULTS
  One hundred forty-two patients met inclusion criteria with 122 correctly diagnosed, 16 incorrect, and 4 inconclusive. Accuracy was 86%, with 95% accuracy in patients with typical coronary patterns, 85% with the most common variant (left coronary from the leftward sinus and right and circumflex from the rightward sinus), and 61% with less common patterns. Typical and common variants were more likely to be correct than atypical patterns (P < .001). Cases with ventricular septal defect were more likely to have correctly diagnosed coronaries than with an intact ventricular septum (94% vs. 79%, P = .01). There was no change in accuracy over time (P > .05). There was no difference in duration of cardiopulmonary bypass, cross-clamp times, length of stay, or postoperative stay between the correct and incorrectly diagnosed groups (P > .05).
  
  
  CONCLUSIONS
  In our center, accuracy of echocardiographic imaging of the coronary arteries in transposition was 86% without improvement over time, and perioperative outcomes were not affected by diagnostic accuracy. Further invasive imaging may not be necessary to determine the coronary pattern in this lesion.
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Fundora
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Enrique Oliver
authors.initials: EO
authors.lastname: Aregullin
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Gil
authors.initials: G
authors.lastname: Wernovsky
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Welch
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Juan-Carlos
authors.initials: JC
authors.lastname: Muniz
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Nao
authors.initials: N
authors.lastname: Sasaki
authors.affiliation: Department of Cardiovascular Surgery, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Hannan
authors.affiliation: Department of Cardiovascular Surgery, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Redmond P
authors.initials: RP
authors.lastname: Burke
authors.affiliation: Department of Pediatric Cardiology, Nicklaus Children's Hospital, Miami Children's Health System, Florida International University, Herbert Wertheim College of Medicine, Miami, Fla, USA.
authors.forename: Leo
authors.initials: L
authors.lastname: Lopez
mesh_terms: D000069278:Arterial Switch Operation; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D018618:Echocardiography, Doppler, Color; D005260:Female; D006776:Hospitals, Pediatric; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D011237:Predictive Value of Tests; D015203:Reproducibility of Results; D012189:Retrospective Studies; D062606:Tertiary Care Centers; D013997:Time Factors; D014188:Transposition of Great Vessels / Q000000981:diagnostic imaging* / Q000601:surgery*; D016896:Treatment Outcome
keywords: Arterial Switch Operation; Coronary Arteries; Echocardiography; Outcomes; Transposition of the Great Arteries