title: [Research Progress on Long Non-Coding RNA in Hematological Malignancies--Review].
abstract: Long non-coding RNA (LncRNA) is defined as a class of transcripts more than 200 nucleotides in length and without the protein-coding function. It has been found for years, however, that little is known about the potential role of LncRNA in humans. But recent studies showed that LncRNA can regulate the coding-gene expression and participate in effects of human body. Accumulating evidence demonstrated that LncRNA are involved in cancer incidence, development and progression.With further exploration on the mechanisms of tumors, the relationship between the long non-coding RNA and hematological malignancies increasingly become a hot research. This review focuses on the mechanisms of LncRNA in hematological malignancies.
authors.affiliation: Department of Hematology, The First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China.
authors.forename: Liu-Yan
authors.initials: LY
authors.lastname: Xin
authors.affiliation: Department of Hematology, The First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China.|Medical Postgraduated School of Nanchang University, Nanchang 330003, Jiangxi Province, China.
authors.forename: Si-Si
authors.initials: SS
authors.lastname: Zhong
authors.affiliation: Department of Hematology, The First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China.
authors.forename: Ai-Fei
authors.initials: AF
authors.lastname: Liu
authors.affiliation: Department of Hematology, The First Affiliated Hospital of Gannan Medical College, Ganzhou 341000, Jiangxi Province, China. E-mail: chenyj2005@163.com.
authors.forename: Yi-Jian
authors.initials: YJ
authors.lastname: Chen
mesh_terms: D019337:Hematologic Neoplasms / Q000235:genetics*; D006801:Humans; D062085:RNA, Long Noncoding / Q000235:genetics*
chemical_list: D062085:RNA, Long Noncoding