title: Myeloid sarcoma of the orbit without systemic recurrence of disease in an adult: A clinicopathological case report.
abstract: Myeloid sarcoma (MS), also known as granulocytic sarcoma (GS) or chloroma (named for the greenish hue attributed to the pigment of myeloperoxidase [MPO]), is a rare solid tumor with a predilection for the orbit. MS usually occurs in conjunction with acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), or myeloproliferative disorder (MPS) and may be the harbinger of disease. Therefore, prompt diagnosis is essential for patient survival. We present a rare case of a 61 year old with an isolated orbital MS without active leukemia.
authors.affiliation: a Rush University Medical Center , Department of Ophthalmology , Chicago , Illinois , USA.
authors.forename: Alexander L
authors.initials: AL
authors.lastname: Grigalunas
authors.affiliation: a Rush University Medical Center , Department of Ophthalmology , Chicago , Illinois , USA.
authors.forename: Thomas R
authors.initials: TR
authors.lastname: Mizen
mesh_terms: D014408:Biomarkers, Tumor; D006801:Humans; D054438:Leukemia, Myeloid, Chronic, Atypical, BCR-ABL Negative / Q000473:pathology*; D051917:Leukosialin / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism; D009918:Orbital Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000601:surgery; D009195:Peroxidase / Q000378:metabolism; D016133:Polymerase Chain Reaction; D023981:Sarcoma, Myeloid / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000378:metabolism / Q000601:surgery
chemical_list: D014408:Biomarkers, Tumor; D051917:Leukosialin; C465014:SPN protein, human; D009195:Peroxidase
keywords: Adult; chloroma; granulocytic sarcoma; myeloid sarcoma; orbit