title: Smart lanthanide coordination polymer fluorescence probe for mercury(II) determination.
abstract: Lanthanide coordination polymers (LCPs) have recently emerged as attractive biosensor materials due to their flexible components, high tailorable properties and unique luminescence features. In this work, we designed a smart LCP probe of Tb-CIP/AMP {(CIP, ciprofloxacin) (AMP, adenosine monophosphate)} for Hg(2+) detection by using lanthanide ions as metal nodes, CIP as ligand molecule, and AMP as bridging linker and recognition unit. Tb-CIP/AMP emits strong green luminescence due to the inclusion of AMP, which withdraws the coordinated water molecules and shields Tb(3+) from the quenching effect of O-H vibration in water molecules. The subsequent addition of Hg(2+) into Tb-CIP/AMP can strongly quench the fluorescence because of the specific coordination interaction between AMP and Hg(2+). As a kind of Hg(2+) nanosensor, the probe exhibited excellent selectivity for Hg(2+) and high sensitivity with detection limit of 0.16 nM. In addition, the probe has long fluorescence lifetime up to millisecond and has been applied to detect Hg(2+) in drinking water and human urine samples with satisfactory results. We envision that our strategy, in the future, could be extended to the designation of other LCP-based hypersensitive time-gated luminescence assays in biological media and biomedical imaging.
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
authors.forename: Baoxia
authors.initials: B
authors.lastname: Liu
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, China.
authors.forename: Yankai
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
authors.forename: Yuanqiang
authors.initials: Y
authors.lastname: Hao
authors.affiliation: College of Biochemical Engineering, Anhui Polytechnic University, Wuhu 241000, China.
authors.forename: Yujie
authors.initials: Y
authors.lastname: Ding
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wei
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, China. Electronic address: qupeng0212@163.com.
authors.forename: Peng
authors.initials: P
authors.lastname: Qu
authors.affiliation: Henan Key Laboratory Cultivation Base of Nanobiological Analytical Chemistry, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, China; College of Chemistry and Molecular Engineering, Zhengzhou University, Zhengzhou 450001, China. Electronic address: xumaotian@sqnc.edu.cn.
authors.forename: Maotian
authors.initials: M
authors.lastname: Xu
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008628:Mercury / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D011108:Polymers / Q000737:chemistry*; D013050:Spectrometry, Fluorescence; D014881:Water Supply
chemical_list: D005456:Fluorescent Dyes; D028581:Lanthanoid Series Elements; D011108:Polymers; D008628:Mercury
keywords: Drinking water; Hg(2+); Human urine; Lanthanide coordination polymers; Tb-CIP/AMP