title: Gemcitabine-Induced Subacute Cutaneous Lupus Erythematosus: A Case Report.
abstract: Subacute cutaneous lupus erythematosus (SCLE) is a rare eruption related to several pharmacological and chemotherapy agents. We present a 63-year-old female with recurrent epithelial ovarian cancer who developed SCLE after administration of gemcitabine. Following discontinuation of gemcitabine and after oral steroid treatment, all skin lesions disappeared. In view of the extensive use of gemcitabine in recurrent ovarian cancer, it is important to be aware of the possibility of SCLE occurrence in these patients.
authors.forename: Masha
authors.initials: M
authors.lastname: Ben Zvi
authors.forename: Hananya
authors.initials: H
authors.lastname: Vaknine
authors.forename: Joseph
authors.initials: J
authors.lastname: Menczer
authors.forename: Ofri
authors.initials: O
authors.lastname: Peled
authors.forename: Erez
authors.initials: E
authors.lastname: Ben Shem
authors.forename: Letizia
authors.initials: L
authors.lastname: Schreiber
authors.forename: Tally
authors.initials: T
authors.lastname: Levy
mesh_terms: D000284:Administration, Oral; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects* / Q000627:therapeutic use; D003841:Deoxycytidine / Q000009:adverse effects / Q000031:analogs & derivatives* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008178:Lupus Erythematosus, Cutaneous / Q000188:drug therapy / Q000209:etiology*; D008198:Lymph Nodes / Q000378:metabolism; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010051:Ovarian Neoplasms / Q000188:drug therapy / Q000601:surgery; D000072078:Positron Emission Tomography Computed Tomography; D011241:Prednisone / Q000627:therapeutic use; D012867:Skin / Q000378:metabolism / Q000473:pathology; D016896:Treatment Outcome; D000093542:Gemcitabine
chemical_list: D000893:Anti-Inflammatory Agents; D000964:Antimetabolites, Antineoplastic; D003841:Deoxycytidine; D011241:Prednisone; D000093542:Gemcitabine