title: Inactivating MUTYH germline mutations in pediatric patients with high-grade midline gliomas.
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: Cassie N
authors.initials: CN
authors.lastname: Kline
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: Nancy M
authors.initials: NM
authors.lastname: Joseph
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: James P
authors.initials: JP
authors.lastname: Grenert
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: Jessica
authors.initials: J
authors.lastname: van Ziffle
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: Iwei
authors.initials: I
authors.lastname: Yeh
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: Boris C
authors.initials: BC
authors.lastname: Bastian
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: Sabine
authors.initials: S
authors.lastname: Mueller
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, California (C.N.K., S.M.); Clinical Cancer Genomics Laboratory, University of California, San Francisco, California (N.M.J., J.P.G., J.v.Z., I.Y., B.C.B.); Departments of Neurology and Neurosurgery, University of California, San Francisco, California (S.M.); Division of Neuropathology, Department of Pathology, University of California, San Francisco, California (D.A.S.).
authors.forename: David A
authors.initials: DA
authors.lastname: Solomon
mesh_terms: D002648:Child; D002675:Child, Preschool; D045647:DNA Glycosylases / Q000235:genetics*; D018095:Germ-Line Mutation; D005910:Glioma / Q000235:genetics* / Q000473:pathology*; D006801:Humans; D008297:Male; D060787:Neoplasm Grading
chemical_list: D045647:DNA Glycosylases; C061738:mutY adenine glycosylase
keywords: ACVR1; MUTYH; Turcot syndrome; familial adenomatous polyposis syndrome type 2; glioma; medulloblastoma; tumor predisposition syndrome