title: [Reproducibility of Gleason scores in prostate cancer].
abstract: OBJECTIVE
  To investigate the reproducibility of Gleason scores for prostate cancer.
  
  
  METHODS
  Based on the revised Gleason Scoring System of the International Society of Urological Pathology ( ISUP) , we analyzed the reproducibility and difference of Gleason scores in 49 cases of prostate cancer using the methods of combination and grouping.
  
  
  RESULTS
  The total reproducibility of Gleason scores among 15 pathologists was good (κ = 0.642), 62.2% by the combination method, the highest in Gleason 5 + 5 (81.2%) and 5 +4 (73.3%), then in Gleason 4 + 4 (67.5%), 3 + 3 (64.0%), 4 +3 (61.3%), and 3 + 4 (44.0%), and the lowest in Gleason 4 + 5 (38.9%) and 3 + 5 (33.3%). The total reproducibility of Gleason scores by the grouping method was 71.4%, the highest in Gleason 9-10 (84.9%) , then in Gleason 7 (76.7%) and 6 (64.0%), and the lowest in Gleason 8 (60.7%).
  
  
  CONCLUSIONS
  The reproducibility of Gleason scores remains to be further improved in prostate cancer, mainly concerning the understanding of Gleason 3 and 4 carcinoma.
authors.forename: Hui-jie
authors.initials: HJ
authors.lastname: He
authors.forename: Gong-wei
authors.initials: GW
authors.lastname: Wang
mesh_terms: D002277:Carcinoma / Q000175:diagnosis*; D006801:Humans; D008297:Male; D060787:Neoplasm Grading; D011471:Prostatic Neoplasms / Q000175:diagnosis*; D015203:Reproducibility of Results