title: Long-term success of dental implant-supported dentures in postirradiated patients treated for neoplasms of the maxillofacial skeleton: a retrospective study.
abstract: OBJECTIVE
  The reconstruction of oral function in irradiated patients with craniofacial tumors is a significant challenge. The aim of this study was to detect long-term success of dental implant-supported dentures in postirradiated patients treated for neoplasms of the maxillofacial skeleton.
  
  
  METHODS
  From 2004 to 2011, 36 irradiated patients underwent oral function reconstruction using implant-supported prostheses. Bone augmentation was completed using vascularized bone grafts in 22 patients. Fourteen patients were treated by hyperbaric oxygen therapy (HBO). A total of 198 dental implants were used in jaw rehabilitation. After loading, implant success rates, biological and prosthetic complications, patient satisfaction, and psychological changes were recorded.
  
  
  RESULTS
  Bone augmentation of the jaw was successful and vascularized grafts provided an additional vascular supply in compromised irradiated tissue. Rehabilitation was successful in all of the patients after loading. Thirty-eight dental implants failed, and 35 implants were removed. The success rate of the implants was 93.6 % for 10 years after loading. It was not a significant difference in implant success rate between the HBO group and the other groups. The prosthodontic maintenance results and complication rates showed that patients required intervention 0.19 times per year. All patients were satisfied with the oral restoration results.
  
  
  CONCLUSIONS
  The restoration of oral function in radiotherapy patients with tumor resection using implant-supported prostheses is a viable treatment option.
  
  
  CONCLUSIONS
  Either alone or in combination with HBO, dental implant-supported prostheses can be used an effective therapeutic approach for irradiated patients with oral function reconstruction.
authors.affiliation: Department of Oral Implants, School of Medicine, Ninth People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Yiqun
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Oral Implants, School of Medicine, Ninth People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Huang
authors.affiliation: Department of Oral Implants, School of Medicine, Ninth People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Oral and Maxillofacial Surgery, School of Medicine, Ninth People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Zhiyuan
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Implants Dentistry, School of Medicine, Ninth People's Hospital affiliated with Shanghai Jiao Tong University, Shanghai, China. zouduohongyy@126.com.
authors.forename: Duohong
authors.initials: D
authors.lastname: Zou
mesh_terms: D000540:Alveolar Ridge Augmentation; D016025:Bone Transplantation; D003131:Combined Modality Therapy; D019094:Dental Prosthesis, Implant-Supported; D005147:Facial Bones / Q000528:radiation effects*; D005260:Female; D005360:Fibula / Q000637:transplantation; D006258:Head and Neck Neoplasms / Q000532:radiotherapy* / Q000601:surgery*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007085:Ilium / Q000637:transplantation; D008297:Male; D008875:Middle Aged; D017060:Patient Satisfaction; D011832:Radiation Injuries / Q000628:therapy*; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Craniofacial tumors; Dental implant-supported dentures; Oral function reconstruction; Radiotherapy