title: [Kikuchi-Fujimoto's disease or histiocytic necrotizing lymphadenitis: A report of two familial cases].
abstract: BACKGROUND
  The histiocytic necrotizing lymphadenitis or Kikuchi-Fujimoto's disease is characterized by a lymph node inflammation whose similarity with systemic lupus is generally admitted.
  
  
  METHODS
  Our description of two familial cases aims at raising the hypothesis of the existence of a genetic background in this disease following the example of what is observed in the autoimmune diseases.
  
  
  CONCLUSIONS
  Pathophysiology of Kikuchi-Fujimoto's disease is probably multifactorial and may include predisposing genetic background and a possible infectious triggering event.
authors.affiliation: Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France. Electronic address: redouane.bakir@ch-aulnay.fr.
authors.forename: R
authors.initials: R
authors.lastname: Bakir
authors.affiliation: Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
authors.forename: A-L
authors.initials: AL
authors.lastname: Lecapitaine
authors.affiliation: Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
authors.forename: J
authors.initials: J
authors.lastname: Chevalier
authors.affiliation: Service d'anatomie pathologique, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
authors.forename: B
authors.initials: B
authors.lastname: Juberthie
authors.affiliation: Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
authors.forename: M-A
authors.initials: MA
authors.lastname: Bouldouyre
authors.affiliation: Service de médecine interne et de maladies infectieuses, centre hospitalier Robert-Ballanger, 1, boulevard Robert-Ballanger, 93602 Aulnay-sous-Bois cedex, France.
authors.forename: H
authors.initials: H
authors.lastname: Gros
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005190:Family; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D055815:Young Adult
keywords: Familial; Heredity; Histiocytic necrotizing lymphadenitis; Hérédité; Kikuchi-Fujimoto's disease; Lymphadénite histiocytaire nécrosante; Maladie de Kikuchi-Fujimoto