title: Acquired Pulmonary Vein Isolation in a Patient with Friedreich Ataxia.
abstract: The electrophysiologic nature of atrial fibrillation (AF) and related atrial arrhythmias in Friedreich ataxia has not previously been characterized. In the presented case, dense atrial scar had progressed to the point of acquired pulmonary vein (PV) isolation before the delivery of a single radiofrequency lesion. AF was induced, and ultimately organized spontaneously into a microreentrant atrial tachycardia. Other atrial tachycardias were also identified near scar border zones; these potentially served as triggers for AF in this patient, independent of the PVs. This case emphasizes the need to address non-PV substrate in some patients undergoing catheter ablation of AF.
authors.affiliation: Cardiac Electrophysiology, Cardiology Division, University of Colorado, Denver, Anschutz Medical Campus, 12401 East 17th Avenue, B-132, Aurora, CO 80045, USA. Electronic address: matthew.zipse@ucdenver.edu.
authors.forename: Matthew M
authors.initials: MM
authors.lastname: Zipse
authors.affiliation: Cardiac Electrophysiology, Cardiology Division, University of Colorado, Denver, Anschutz Medical Campus, 12401 East 17th Avenue, B-132, Aurora, CO 80045, USA. Electronic address: ryan.aleong@ucdenver.edu.
authors.forename: Ryan G
authors.initials: RG
authors.lastname: Aleong
mesh_terms: D000328:Adult; D001281:Atrial Fibrillation / Q000150:complications / Q000503:physiopathology / Q000601:surgery; D017115:Catheter Ablation; D005621:Friedreich Ataxia / Q000150:complications*; D006325:Heart Atria / Q000503:physiopathology; D006801:Humans; D008297:Male; D011667:Pulmonary Veins / Q000502:physiology / Q000601:surgery
keywords: Arrhythmia; Atrial fibrillation; Cardiomyopathy; Friedreich ataxia