title: A Diet and Fitness Program Similarly Affects Weight Reduction in Schizophrenia Patients Treated with Typical or Atypical Medications.
abstract: BACKGROUND
  Schizophrenia patients, receiving new generation antipsychotics, many times suffer from obesity sometimes leading to metabolic syndrome. Diet and fitness programs which reduce weight should be combined in the treatment plan of these patients. This study evaluated patients' adherence and the effect of a diet and fitness program in schizophrenia patients treated with typical vs. atypical antipsychotics.
  
  
  METHODS
  106 stabilized schizophrenia patients participated in a 9-months diet and fitness program, receiving their own menu and a personal workout plan.
  
  
  RESULTS
  60 patients (57%), 27.8±4.8y age, participated in the program for at least one month, i. e., adherent participants, with 4.0±2 months participation average. Months of participation were correlated with weight loss (r=-0.417; p=0.002). Throughout the study patients lost 3.34±1.2 kg in average: 85.95±14.66 at baseline and 82.61±13.78 at the end of program (t=4.969; p<0.001). No association was found between specific types or dose of medication and weight loss (F=0.437, p=0.85).
  
  
  CONCLUSIONS
  Patients with schizophrenia are capable of adhering to a diet and fitness program and successfully lose weight, regardless to taking typical or atypical medications.
authors.affiliation: Psychiatry Division, the Chaim Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: R
authors.initials: R
authors.lastname: Amiaz
authors.affiliation: Psychiatry Division, the Chaim Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: K
authors.initials: K
authors.lastname: Rubinstein
authors.affiliation: Psychiatry Division, the Chaim Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Czerniak
authors.affiliation: Sackler Faculty of Medicine, Tel Aviv University, Tel-Aviv, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Karni
authors.affiliation: Psychiatry Division, the Chaim Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Weiser
mesh_terms: D000328:Adult; D014150:Antipsychotic Agents / Q000627:therapeutic use; D015992:Body Mass Index; D004032:Diet; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D010809:Physical Fitness / Q000502:physiology*; D012559:Schizophrenia / Q000178:diet therapy* / Q000188:drug therapy / Q000534:rehabilitation*; D016896:Treatment Outcome; D015431:Weight Loss; D055815:Young Adult
chemical_list: D014150:Antipsychotic Agents