title: Deterioration of dyslexia after non-dominant temporal lobectomy for drug-resistant epilepsy.
abstract: We present a patient with drug-resistant right-sided temporal lobe epilepsy, caused by a ganglioglioma of the parahippocampal gyrus. Preoperatively, the patient was also known to have dyslexia. A right-sided anterior temporal lobectomy, including complete lesionectomy, was performed. Several months after the otherwise uncomplicated procedure, the patient complained about visual memory disturbances, accompanied by increased reading and spelling problems. Postoperative neuropsychological examination revealed deterioration of the visual memory functions, compared to the preoperative assessment, and consequently provided a possible explanation for worsening of the pre-existing dyslexia. In this case report, we hypothesize on the cause of this unusual deterioration and present recommendations to be included in the preoperative epilepsy surgery evaluation for patients with verbal or reading disorders such as dyslexia.
authors.affiliation: Department of Neurosurgery, Maastricht University Medical Centre, Maastricht.
authors.forename: Roel H L
authors.initials: RH
authors.lastname: Haeren
authors.affiliation: Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Centre, Heeze/Maastricht, Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen.
authors.forename: Marc P H
authors.initials: MP
authors.lastname: Hendriks
authors.affiliation: Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Centre, Heeze/Maastricht, Department of Neurology, Maastricht University Medical Centre, Maastricht.
authors.forename: Marielle
authors.initials: M
authors.lastname: Vlooswijk
authors.affiliation: Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Centre, Heeze/Maastricht.
authors.forename: Lex
authors.initials: L
authors.lastname: Verdyck
authors.affiliation: Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Centre, Heeze/Maastricht, Department of Clinical Neurophysiology, Maastricht University Medical Centre, Maastricht.
authors.forename: Vivianne H J M
authors.initials: VH
authors.lastname: van Kranen-Mastenbroek
authors.affiliation: Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Centre, Heeze/Maastricht.
authors.forename: Louis
authors.initials: L
authors.lastname: Wagner
authors.affiliation: Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands.
authors.forename: Sophie
authors.initials: S
authors.lastname: van Benthum
authors.affiliation: Department of Neurosurgery, Maastricht University Medical Centre, Maastricht, Academic Centre for Epileptology, Kempenhaeghe/Maastricht University Medical Centre, Heeze/Maastricht.
authors.forename: Olaf E M G
authors.initials: OE
authors.lastname: Schijns
mesh_terms: D038481:Anterior Temporal Lobectomy / Q000379:methods; D004410:Dyslexia / Q000175:diagnosis / Q000209:etiology*; D004833:Epilepsy, Temporal Lobe / Q000175:diagnosis / Q000601:surgery*; D005260:Female; D006801:Humans; D008568:Memory / Q000502:physiology*; D008569:Memory Disorders / Q000175:diagnosis / Q000473:pathology; D013702:Temporal Lobe / Q000601:surgery*; D055815:Young Adult
keywords: complication; dyslexia; epilepsy surgery; temporal lobe epilepsy; visual memory