title: Effect of statin use on pain relief by transforaminal epidural steroid injection.
abstract: OBJECTIVE
  To investigate the impact of statin use on response to fluoroscopy-assisted transforaminal anterior epidural steroid injection (TAESI).
  
  
  METHODS
  Patients undergoing TAESI for low back pain were recruited and stratified according to statin use. Pain was evaluated with a visual analogue scale (VAS) before and at 1, 3, and 6 months after TAESI. Health-related quality-of-life was evaluated using the Short Form 36 (SF-36) questionnaire 6 months after TAESI.
  
  
  RESULTS
  There were no significant differences in VAS scores after TAESI between statin users (n = 40) and statin nonusers (n = 253). The SF-36 subgroup: role limitations due to emotional problems score was significantly lower in statin users than statin nonusers. There were no significant between-group differences in any other SF-36 parameter.
  
  
  CONCLUSIONS
  Statin use had no effect on pain scores after TAESI.
authors.affiliation: Department of Anaesthesia and Reanimation, Adnan Menderes University Medical Faculty, Aydin, Turkey sarisinem@yahoo.com.
authors.forename: Sinem
authors.initials: S
authors.lastname: Sari
authors.affiliation: Department of Algology, Adnan Menderes University, Aydin, Turkey.
authors.forename: Osman Nuri
authors.initials: ON
authors.lastname: Aydın
authors.affiliation: Department of Anaesthesia and Reanimation, Adnan Menderes University Medical Faculty, Aydin, Turkey.
authors.forename: Banu
authors.initials: B
authors.lastname: Tasdemir
authors.affiliation: Cleveland Clinic, Lerner College of Medicine, Cleveland, OH, USA.
authors.forename: Fabrizio
authors.initials: F
authors.lastname: Galimberti
authors.affiliation: Department of Outcomes Research, Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Turan
mesh_terms: D000328:Adult; D000368:Aged; D000700:Analgesics / Q000627:therapeutic use*; D002045:Bupivacaine / Q000627:therapeutic use*; D004338:Drug Combinations; D005260:Female; D005471:Fluoroscopy; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D007268:Injections, Epidural; D017116:Low Back Pain / Q000188:drug therapy* / Q000503:physiopathology; D008159:Lumbar Vertebrae / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D059408:Pain Management / Q000379:methods; D010147:Pain Measurement / Q000379:methods; D011446:Prospective Studies; D011843:Radiculopathy / Q000188:drug therapy* / Q000503:physiopathology; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000627:therapeutic use*
chemical_list: D000700:Analgesics; D004338:Drug Combinations; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors; D014222:Triamcinolone Acetonide; D002045:Bupivacaine
keywords: Statin; pain; transforaminal epidural steroid injection