title: Developments in high-speed countercurrent chromatography and its applications in the separation of terpenoids and saponins.
abstract: High-speed countercurrent chromatography is a liquid-liquid separation chromatographic technique, which has the unique feature of eliminating irreversible adsorption using liquid support medium, and is widely used in research and development of traditional Chinese medicine, biochemistry, food, environment analysis, and so on. In this review, some new developments of countercurrent chromatography, for instance cross-axis countercurrent chromatography, dual countercurrent chromatography, foam countercurrent chromatography, and pH-zone-refining countercurrent chromatography are presented. Furthermore, the research and progress in high-speed countercurrent chromatography techniques and its application in the separation and purification of terpenoids and saponins are reviewed.
authors.affiliation: Department of Pharmacy, School of Pharmaceutical Science, Xiamen University, Xiamen, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Song
authors.affiliation: Department of Pharmacy, School of Pharmaceutical Science, Xiamen University, Xiamen, China.
authors.forename: Jianhong
authors.initials: J
authors.lastname: Lin
authors.affiliation: Department of Pharmacy, School of Pharmaceutical Science, Xiamen University, Xiamen, China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Department of Pharmacy, School of Pharmaceutical Science, Xiamen University, Xiamen, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Chen
mesh_terms: D003377:Countercurrent Distribution; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013729:Terpenes / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012503:Saponins; D013729:Terpenes
keywords: countercurrent chromatography; saponins; terpenoids