title: Ebola or Not? Evaluating the Ill Traveler From Ebola-Affected Countries in West Africa.
abstract: Background.  The 2014-2015 Ebola epidemic in West Africa had global impact beyond the primarily affected countries of Guinea, Liberia, and Sierra Leone. Other countries, including the United States, encountered numerous patients who arrived from highly affected countries with fever or other signs or symptoms consistent with Ebola virus disease (EVD). Methods.  We describe our experience evaluating 25 travelers who met the US Centers for Disease Control and Prevention case definition for a person under investigation (PUI) for EVD from July 20, 2014 to January 28, 2015. All patients were triaged and evaluated under the guidance of institutional protocols to the emergency department, outpatient tropical medicine clinic, or Emory's Ebola treatment unit. Strict attention to infection control and early involvement of public health authorities guided the safe evaluation of these patients. Results.  None were diagnosed with EVD. Respiratory illnesses were common, and 8 (32%) PUI were confirmed to have influenza. Four patients (16%) were diagnosed with potentially life-threatening infections or conditions, including 3 with Plasmodium falciparum malaria and 1 with diabetic ketoacidosis. Conclusions.  In addition to preparing for potential patients with EVD, Ebola assessment centers should consider other life-threatening conditions requiring urgent treatment, and travelers to affected countries should be strongly advised to seek pretravel counseling. Furthermore, attention to infection control in all aspects of PUI evaluation is paramount and has presented unique challenges. Lessons learned from our evaluation of potential patients with EVD can help inform preparations for future outbreaks of highly pathogenic communicable diseases.
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Jessica K
authors.initials: JK
authors.lastname: Fairley
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Phyllis E
authors.initials: PE
authors.lastname: Kozarsky
authors.affiliation: Division of Infectious Diseases, Department of Medicine; Department of Pathology and Laboratory Medicine.
authors.forename: Colleen S
authors.initials: CS
authors.lastname: Kraft
authors.affiliation: Division of Infectious Diseases, Department of Medicine; Department of Pathology and Laboratory Medicine.
authors.forename: Jeannette
authors.initials: J
authors.lastname: Guarner
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: James P
authors.initials: JP
authors.lastname: Steinberg
authors.affiliation: Division of Infectious Diseases, Department of Medicine; Division of Pediatric Infectious Diseases, Department of Pediatrics.
authors.forename: Evan
authors.initials: E
authors.lastname: Anderson
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Jesse T
authors.initials: JT
authors.lastname: Jacob
authors.affiliation: Department of Emergency Medicine , Emory University.
authors.forename: Patrick
authors.initials: P
authors.lastname: Meloy
authors.affiliation: Department of Emergency Medicine , Emory University.
authors.forename: Darria
authors.initials: D
authors.lastname: Gillespie
authors.affiliation: Department of Emergency Medicine , Emory University.
authors.forename: Tamara R
authors.initials: TR
authors.lastname: Espinoza
authors.affiliation: Department of Emergency Medicine , Emory University.
authors.forename: Alexander
authors.initials: A
authors.lastname: Isakov
authors.affiliation: Emory Healthcare.
authors.forename: Sharon
authors.initials: S
authors.lastname: Vanairsdale
authors.affiliation: Department of Quality and Safety: Infection Prevention and Control , Emory Healthcare , Atlanta, Georgia.
authors.forename: Esther
authors.initials: E
authors.lastname: Baker
authors.affiliation: Division of Infectious Diseases, Department of Medicine.
authors.forename: Henry M
authors.initials: HM
authors.lastname: Wu
keywords: Ebola virus disease; clinical screening; fever; travel medicine