title: Graphene Oxide and Lipid Membranes: Size-Dependent Interactions.
abstract: We have investigated the interaction of graphene oxide (GO) sheets with supported lipid membranes with focus on how the interaction depends on GO sheet size (three samples in the range of 90-5000 nm) and how it differs between small and large liposomes. The layer-by-layer assembly of these materials into multilamellar structures, as discovered in our previous research, is now further explored. The interaction processes were monitored by two complementary, real time, surface-sensitive analytical techniques: quartz crystal microbalance with dissipation monitoring (QCM-D, electroacoustic sensing) and indirect nanoplasmonic sensing (INPS, optical sensing). The results show that the sizes of each of the two components, graphene oxide and liposomes, are important parameters affecting the resulting multilayer structures. Spontaneous liposome rupture onto graphene oxide is obtained for large lateral dimensions of the graphene oxide sheets.
authors.affiliation: Department of Energy and Environment and ‡Department of Applied Physics, Chalmers University of Technology , SE-412 96 Göteborg, Sweden.
authors.forename: Rickard
authors.initials: R
authors.lastname: Frost
authors.affiliation: Department of Energy and Environment and ‡Department of Applied Physics, Chalmers University of Technology , SE-412 96 Göteborg, Sweden.
authors.forename: Sofia
authors.initials: S
authors.lastname: Svedhem
authors.affiliation: Department of Energy and Environment and ‡Department of Applied Physics, Chalmers University of Technology , SE-412 96 Göteborg, Sweden.
authors.forename: Christoph
authors.initials: C
authors.lastname: Langhammer
authors.affiliation: Department of Energy and Environment and ‡Department of Applied Physics, Chalmers University of Technology , SE-412 96 Göteborg, Sweden.
authors.forename: Bengt
authors.initials: B
authors.lastname: Kasemo
mesh_terms: D002794:Choline / Q000031:analogs & derivatives / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D008081:Liposomes / Q000737:chemistry*; D010169:Palmitic Acids / Q000737:chemistry; D010316:Particle Size; D010713:Phosphatidylcholines / Q000737:chemistry; D058525:Quartz Crystal Microbalance Techniques; D012822:Silicon Dioxide
chemical_list: C000613173:1-palmitoyl-2-oleyl-sn-glycero-3-ethylphosphocholine; D008081:Liposomes; D010169:Palmitic Acids; D010713:Phosphatidylcholines; D012822:Silicon Dioxide; D006108:Graphite; D002794:Choline; C028694:1-palmitoyl-2-oleoylphosphatidylcholine