title: Change in the diagnosis from classical Hodgkin's lymphoma to anaplastic large cell lymphoma by (18)F flourodeoxyglucose positron emission tomography/computed tomography: Importance of recognising disease pattern on imaging and immunohistochemistry.
abstract: Anaplastic large cell lymphoma (ALCL) is a rare type of nonHodgkin's lymphoma (NHL), but one of the most common subtypes of T-cell lymphoma. It is an aggressive T-cell lymphoma, and some ALCL may mimic less aggressive classical HL histopathlogically. It may be misdiagnosed unless careful immunohistochemical examination is performed. As the prognosis and management of these two lymphomas vary significantly, it is important to make a correct diagnosis. We describe a case who was diagnosed as classical HL by histopathological examination of cervical lymph node, in whom (18)F-flouro deoxyglucose positron emission tomography/computed tomography appearances were unusual for HL and warranted review of histopathology that revealed anaplastic lymphoma kinase-1 negative anaplastic large T-cell lymphoma, Hodgkin-like variant, thereby changing the management.
authors.affiliation: Department of Nuclear Medicine, Global Hospitals, Chennai, Tamil Nadu, India.
authors.forename: Raja
authors.initials: R
authors.lastname: Senthil
authors.affiliation: Department of Pathology, Global Hospitals, Chennai, Tamil Nadu, India.
authors.forename: Ranjan Kumar
authors.initials: RK
authors.lastname: Mohapatra
authors.affiliation: Department of Medical Oncology, SIMS Vadapalani, Chennai, Tamil Nadu, India.
authors.forename: Mouleeswaran Koramadai
authors.initials: MK
authors.lastname: Sampath
authors.affiliation: Department of Nuclear Medicine, Global Hospitals, Chennai, Tamil Nadu, India.
authors.forename: Sumati
authors.initials: S
authors.lastname: Sundaraiya
keywords: 18F-flouro deoxyglucose positron emission tomography/computed tomography; Anaplastic large cell lymphoma; Hodgkin's lymphoma