title: Amino acids-incorporated nanoflowers with an intrinsic peroxidase-like activity.
abstract: Functional molecules synthesized by self-assembly between inorganic salts and amino acids have attracted much attention in recent years. A simple method is reported here for fabricating hybrid organic-inorganic nanoflowers using copper (II) ions as the inorganic component and natural amino acids as the organic component. The results indicate that the interactions between amino acid and copper ions cause the growth of the nanoflowers composed by C, N, Cu, P and O elements. The Cu ions and Cu(AA)n complexes containing Cu-O bond are present in the nanoflowers. The nanoflowers have flower-like porous structure dominated by the R groups of amino acids with high surface-to-volume ratios, which is beneficial for exerting its peroxidase-like activity depending on Fenton-like reaction mechanism with ABTS and Rhodamine B as the substrates. It is expected that the nanoflowers hold great promise as enzyme mimics for application in the field of biosensor, bioanalysis and biocatalysis.
authors.affiliation: Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, Changchun, 130012, China.|College of Life Science, Jilin Agricultural University, Changchun, 130118, China.
authors.forename: Zhuo-Fu
authors.initials: ZF
authors.lastname: Wu
authors.affiliation: Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, Changchun, 130012, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
authors.forename: Ya-Li
authors.initials: YL
authors.lastname: Ma
authors.affiliation: The Third Hospital of Jilin University, Changchun, 130033, China.
authors.forename: Cheng-Yan
authors.initials: CY
authors.lastname: He
authors.affiliation: Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, Changchun, 130012, China.
authors.forename: Heng
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, Changchun, 130012, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Chen
authors.affiliation: State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun, 130012, China.
authors.forename: Qi-Sheng
authors.initials: QS
authors.lastname: Huo
authors.affiliation: Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, Changchun, 130012, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Wang
authors.affiliation: Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, College of Life Science, Jilin University, Changchun, 130012, China.
authors.forename: Zheng-Qiang
authors.initials: ZQ
authors.lastname: Li
mesh_terms: D000596:Amino Acids / Q000737:chemistry*; D055162:Biocatalysis; D015374:Biosensing Techniques; D003300:Copper / Q000737:chemistry*; D049329:Nanostructures / Q000737:chemistry*; D010544:Peroxidases / Q000378:metabolism*
chemical_list: D000596:Amino Acids; D003300:Copper; D010544:Peroxidases