title: Characterization data of gilthead sea bream (Sparus aurata) IGF-I receptors (IGF-IRa/Rb).
abstract: In this data article we describe the coding sequence of two IGF-IR paralogues (IGF-IRa and IGF-IRb) obtained from gilthead sea bream embryos. The putative protein architecture (domains and other important motifs) was determined and, amino acid sequences alignment and phylogenetic analysis of both receptors together with IGF-IR orthologues from different vertebrates was performed. Additionally, a semi-quantitative conventional PCR was done to analyze the mRNA expression of both receptors in different tissues of gilthead sea bream. These data will assist in further physiological studies in this species. In this sense, the expression of both receptors during ontogeny in muscle as well as the differential effects of IGF-I and IGF-II on their regulation during in vitro myogenesis has been recently studied (doi: 10.1016/j.ygcen.2015.11.011; [1]).
authors.affiliation: Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain.
authors.forename: Emilio J
authors.initials: EJ
authors.lastname: Vélez
authors.affiliation: Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran; Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, 08028 Barcelona, Spain. Visitor PhD student.
authors.forename: Sheida
authors.initials: S
authors.lastname: Azizi
authors.affiliation: Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Salmerón
authors.affiliation: Department of Biochemistry and Molecular Biology and Department of Medicine and the Howard Hughes Medical Institute, University of Chicago, Chicago, IL 60637, USA.
authors.forename: Shu Jin
authors.initials: SJ
authors.lastname: Chan
authors.affiliation: Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Nematollahi
authors.affiliation: Department of Fisheries Sciences, Faculty of Natural Resources, University of Tehran, Karaj, Iran.
authors.forename: Bagher Mojazi
authors.initials: BM
authors.lastname: Amiri
authors.affiliation: Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Navarro
authors.affiliation: Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain.
authors.forename: Encarnación
authors.initials: E
authors.lastname: Capilla
authors.affiliation: Departament de Fisiologia i Immunologia, Facultat de Biologia, Universitat de Barcelona, Avinguda Diagonal 643, 08028 Barcelona, Spain.
authors.forename: Joaquim
authors.initials: J
authors.lastname: Gutiérrez
keywords: Gilthead sea bream; IGF-I receptors