title: Nitrofurantoin-induced interstitial pneumonitis: albeit rare, should not be missed.
abstract: Interstitial lung disease (ILD) is a rare adverse effect of nitrofurantoin and can range from benign infiltrates to a fatal condition. Nitrofurantoin acts via inhibiting the protein synthesis in bacteria by helping reactive intermediates and is known to produce primary lung parenchymal injury through an oxidant mechanism. Stopping the drug leads to complete recovery of symptoms. In this report, we present a case of nitrofurantoin-induced ILD with the recovery of symptoms and disease process after stopping the drug.
authors.affiliation: Department of Internal Medicine, Hurley Medical Center/Michigan State University, Flint, Michigan, USA.
authors.forename: Haamid
authors.initials: H
authors.lastname: Syed
authors.affiliation: Department of Internal Medicine, Hurley Medical Center/Michigan State University, Flint, Michigan, USA.
authors.forename: Ghassan
authors.initials: G
authors.lastname: Bachuwa
authors.affiliation: Department of Internal Medicine, Hurley Medical Center/Michigan State University, Flint, Michigan, USA.
authors.forename: Sunil
authors.initials: S
authors.lastname: Upadhaya
authors.affiliation: Department of Internal Medicine, Hurley Medical Center/Michigan State University, Flint, Michigan, USA Department of Internal Medicine, Henry Ford Hospital, Detroit, Michigan, USA.
authors.forename: Firas
authors.initials: F
authors.lastname: Abed
mesh_terms: D000328:Adult; D000892:Anti-Infective Agents, Urinary / Q000009:adverse effects; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000139:chemically induced* / Q000175:diagnosis; D009582:Nitrofurantoin / Q000009:adverse effects*
chemical_list: D000892:Anti-Infective Agents, Urinary; D009582:Nitrofurantoin