title: Autoimmune bullous diseases with skin and eye involvement: Cicatricial pemphigoid, pemphigus vulgaris, and pemphigus paraneoplastica.
abstract: Autoimmune blistering diseases are a heterogeneous group of disorders that mostly affect the skin and mucous membranes. Occasionally, other organ systems may be involved, depending on the unique pathophysiology of each disease. Cicatricial pemphigoid, pemphigus vulgaris, and paraneoplastic pemphigus are distinct entities, but all have the potential to have cutaneous and ocular involvement. Awareness and early recognition of ocular involvement in these diseases is important given the increased risk for vision loss and blindness with delay in management. Several skin diseases may be associated with involvement of the external eye. The most common autoimmune diseases are cicatricial pemphigoid, pemphigus vulgaris, and paraneoplastic pemphigus.
authors.affiliation: Department of Medicine (Dermatology), Vanderbilt University School of Medicine, Nashville, TN.
authors.forename: Karen C
authors.initials: KC
authors.lastname: Broussard
authors.affiliation: Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD.
authors.forename: Theresa G
authors.initials: TG
authors.lastname: Leung
authors.affiliation: Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD.
authors.forename: Ahmadreza
authors.initials: A
authors.lastname: Moradi
authors.affiliation: Division of Ocular Immunology, Department of Ophthalmology, Johns Hopkins School of Medicine, Baltimore, MD; Department of Epidemiology, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD.
authors.forename: Jennifer E
authors.initials: JE
authors.lastname: Thorne
authors.affiliation: Department of Medicine (Dermatology), Vanderbilt University School of Medicine, Nashville, TN; Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN.
authors.forename: Jo-David
authors.initials: JD
authors.lastname: Fine
mesh_terms: D000818:Animals; D006801:Humans; D009059:Mouth Diseases / Q000209:etiology; D010257:Paraneoplastic Syndromes / Q000150:complications* / Q000276:immunology / Q000628:therapy; D010390:Pemphigoid, Benign Mucous Membrane / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology; D010392:Pemphigus / Q000150:complications* / Q000188:drug therapy / Q000453:epidemiology / Q000276:immunology