title: Double pathology, sarcoidosis associated with multiple myeloma: A case report.
abstract: The association of sarcoidosis with multiple myeloma is not well known. Including this case report, 12 cases of patients with both sarcoidosis and multiple myeloma have been reported in the literature. The skeletal lesions of both conditions have many clinical and radiological similarities, and unless clinicians are aware of the association and the possibility of dual pathologies, the diagnosis of multiple myeloma in patients known with sarcoidosis may be missed. We present a case of a patient known with longstanding sarcoidosis who was found to have multiple lesions on magnetic resonance imaging (MRI) involving the pelvis and both proximal femurs. Histological analysis revealed the presence of both non-necrotising granulomas consistent with sarcoidosis, and sheets of plasma cells consistent with a plasma cell neoplasm.
authors.affiliation: Department of Orthopaedic Surgery, University of Cape Town, Cape Town, South Africa.
authors.forename: Robert
authors.initials: R
authors.lastname: Dachs
authors.affiliation: Department of Orthopaedic Surgery, University of Cape Town, Cape Town, South Africa.
authors.forename: Anria
authors.initials: A
authors.lastname: Horn
authors.affiliation: Division of Clinical Haematology, University of Cape Town, Cape Town, South Africa.
authors.forename: Hannes
authors.initials: H
authors.lastname: Koornhof
authors.affiliation: Division of Anatomical Pathology, University Of Cape Town, Cape Town, South Africa.
authors.forename: Louis
authors.initials: L
authors.lastname: de Jager
authors.affiliation: Department of Orthopaedic Surgery, University of Cape Town, Cape Town, South Africa.
authors.forename: Sithombo
authors.initials: S
authors.lastname: Maqungo
authors.affiliation: Department of Orthopaedic Surgery, University of Cape Town, Cape Town, South Africa.
authors.forename: Stephen
authors.initials: S
authors.lastname: Roche
keywords: Case report; Lymphoproliferative disorder; Multiple myeloma; Sarcoidosis; Skeletal