title: Rhodococcus equi hyperimmune plasma decreases pneumonia severity after a randomised experimental challenge of neonatal foals.
abstract: Since a vaccine is not available against Rhodococcus equi, R equi-specific hyperimmune plasma (HIP) is commonly used, although its efficacy remains controversial. The objective of this study was to evaluate the ability of a commercially available HIP to prevent clinical rhodococcal pneumonia in neonatal foals after experimental challenge.
authors.affiliation: Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, KY, 40546-0099, USA.
authors.forename: M G
authors.initials: MG
authors.lastname: Sanz
authors.affiliation: Veterinary Diagnostic Laboratory, Department of Veterinary Science, University of Kentucky, Lexington, KY, 40546-0099, USA.
authors.forename: A
authors.initials: A
authors.lastname: Loynachan
authors.affiliation: Maxwell H. Gluck Equine Research Center, University of Kentucky, Lexington, KY, 40546-0099, USA.
authors.forename: D W
authors.initials: DW
authors.lastname: Horohov
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000097:blood / Q000276:immunology*; D000907:Antibodies, Bacterial / Q000097:blood; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D006734:Horse Diseases / Q000517:prevention & control*; D006736:Horses; D010949:Plasma / Q000276:immunology*; D018410:Pneumonia, Bacterial / Q000517:prevention & control / Q000662:veterinary*; D016929:Rhodococcus equi / Q000276:immunology*; D012720:Severity of Illness Index; D016896:Treatment Outcome
chemical_list: D000907:Antibodies, Bacterial
keywords: Bacterial diseases; Horses; Respiratory disease