title: The beneficial effects of taurine in preventing metabolic syndrome.
abstract: Metabolic syndrome, a cluster of risk factors for diabetes and cardiovascular disease, has become a very serious public health concern. A number of studies have provided evidence that taurine has an efficient action against metabolic syndrome, which includes reducing triglycerides to prevent obesity, improving insulin resistance to regulate glucose metabolism, lowering cholesterol (especially decreasing VLDL + LDL cholesterol and increasing HDL cholesterol) to prevent diet-induced hypercholesterolemia, and regulating the renin-angiotensin-aldosterone system and the kallikrein-kinin system etc. to reduce blood pressure. This review summarizes the data from in vitro, animal and limited human studies of beneficial effects of taurine on obesity, dyslipidaemia, diabetes mellitus and hypertension, and addresses the possible metabolic and molecular mechanisms of the prevention of metabolic syndrome by taurine.
authors.affiliation: Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100191, P.R. China. wlchenwen@buu.edu.cn.
authors.forename: Wen
authors.initials: W
authors.lastname: Chen
authors.affiliation: Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100191, P.R. China. wlchenwen@buu.edu.cn.
authors.forename: Junxia
authors.initials: J
authors.lastname: Guo
authors.affiliation: Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100191, P.R. China. wlchenwen@buu.edu.cn.
authors.forename: Yanzhen
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Beijing Key Laboratory of Bioactive Substances and Functional Foods, Beijing Union University, Beijing 100191, P.R. China. wlchenwen@buu.edu.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001794:Blood Pressure; D002784:Cholesterol / Q000097:blood; D006801:Humans; D024821:Metabolic Syndrome / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D013654:Taurine / Q000008:administration & dosage*
chemical_list: D013654:Taurine; D002784:Cholesterol