title: Trend of cancer risk of Chinese inhabitants to dioxins due to changes in dietary patterns: 1980-2009.
abstract: Food ingestion is a major route for human exposure and body burden to dioxins. We estimated the potential influence of changes in dietary patterns in Chinese population on human health risk to 2,3,7,8-TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) over the last three decades. We performed multiple modeling scenario investigations to discriminate the contribution of 2,3,7,8-TCDD emissions and changes in dietary patterns to the cancer risks (CR) to dioxins. Results showed that changes in dietary patterns, featured by decreasing consumption of total grain (including all unprocessed grains) and vegetables and increasing intake of animal-derived foodstuffs, caused increasing CR from 7.3 × 10(-8) in 1980 to 1.1 × 10(-7) in 2009. Varying dietary patterns contributed 17% to the CR of Chinese population in 2009 under the fixed emission in 1980. The CR to 2,3,7,8-TCDD in urban and eastern China residents was higher considerably than those who lived in rural area and western China, attributable to higher emissions, household income, and greater intake of animal-derived foodstuffs in urban and eastern China inhabitants. On the other hand, more rapid increasing trend of the CR was found in rural residents due to their more rapid increase in the consumption of fat-dominated foods as compared with urban residents.
authors.affiliation: Key Laboratory for Environmental Pollution Prediction and Control, Gansu Province; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Huang
authors.affiliation: Key Laboratory for Environmental Pollution Prediction and Control, Gansu Province; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China.
authors.forename: Wanyanhan
authors.initials: W
authors.lastname: Jiang
authors.affiliation: Key Laboratory for Environmental Pollution Prediction and Control, Gansu Province; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China.
authors.forename: Zaili
authors.initials: Z
authors.lastname: Ling
authors.affiliation: Key Laboratory for Environmental Pollution Prediction and Control, Gansu Province; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Key Laboratory for Environmental Pollution Prediction and Control, Gansu Province; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Gao
authors.affiliation: Key Laboratory for Environmental Pollution Prediction and Control, Gansu Province; College of Earth and Environmental Sciences, Lanzhou University, Lanzhou, 730000, China.|CAS Center for Excellence in Tibetan Plateau Earth Sciences, Chinese Academy of Sciences, Beijing, 100101, China.
authors.forename: Jianmin
authors.initials: J
authors.lastname: Ma
mesh_terms: D002681:China / Q000453:epidemiology; D004147:Dioxins / Q000009:adverse effects*; D005247:Feeding Behavior; D005506:Food Contamination; D005843:Geography; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology* / Q000209:etiology* / Q000266:history; D000072317:Polychlorinated Dibenzodioxins / Q000009:adverse effects; D012306:Risk; D012424:Rural Population; D062211:Spatio-Temporal Analysis; D014505:Urban Population
chemical_list: D004147:Dioxins; D000072317:Polychlorinated Dibenzodioxins