title: Gene Amplification: Trophoblast Giant Cells Use All the Tricks.
abstract: Evolutionary gene duplication, developmental endoreduplication and selective gene amplification are alternative strategies for increasing gene copy number. When these processes occur together, things get really interesting, and new work shows that is the lifestyle of cells in the placenta.
authors.affiliation: Department of Comparative Biology and Experimental Medicine, University of Calgary, Calgary, Alberta, T1S 1A2 Canada. Electronic address: jcross@ucalgary.ca.
authors.forename: James C
authors.initials: JC
authors.lastname: Cross
mesh_terms: D002454:Cell Differentiation; D005784:Gene Amplification; D015726:Giant Cells; D010920:Placenta; D014327:Trophoblasts