title: Physiological Correlates of Maternal Responsivity in Mothers of Preschoolers With Fragile X Syndrome.
abstract: The present study examined the relationship between salivary cortisol and maternal responsiveness in mothers of boys with fragile X syndrome (FXS). Maternal responsivity is strongly associated with child outcomes, and children with FXS are at risk for compromised development due to intellectual disability and problem behavior. Increased understanding of the nature and underlying mechanisms of maternal responsivity in FXS is important to optimize outcomes in children with FXS and contribute to improved family cohesion. Data from 36 mother-child dyads indicated a complex age effect with elevated cortisol levels associated with high maternal responsivity scores when children are young and low responsivity scores when children are older. Implications of these findings and directions for future research are discussed.
authors.affiliation: Ashley N. Robinson, Kennedy Krieger Institute;|Jane E. Roberts, University of South Carolina;|Nancy C. Brady, University of Kansas;|Samuel D. McQuillin, University of Houston; and.|Steven F. Warren, University of Kansas.
authors.forename: Ashley N
authors.initials: AN
authors.lastname: Robinson
authors.affiliation: Ashley N. Robinson, Kennedy Krieger Institute;|Jane E. Roberts, University of South Carolina;|Nancy C. Brady, University of Kansas;|Samuel D. McQuillin, University of Houston; and.|Steven F. Warren, University of Kansas.
authors.forename: Jane E
authors.initials: JE
authors.lastname: Roberts
authors.affiliation: Ashley N. Robinson, Kennedy Krieger Institute;|Jane E. Roberts, University of South Carolina;|Nancy C. Brady, University of Kansas;|Samuel D. McQuillin, University of Houston; and.|Steven F. Warren, University of Kansas.
authors.forename: Nancy C
authors.initials: NC
authors.lastname: Brady
authors.affiliation: Ashley N. Robinson, Kennedy Krieger Institute;|Jane E. Roberts, University of South Carolina;|Nancy C. Brady, University of Kansas;|Samuel D. McQuillin, University of Houston; and.|Steven F. Warren, University of Kansas.
authors.forename: Samuel D
authors.initials: SD
authors.lastname: McQuillin
authors.affiliation: Ashley N. Robinson, Kennedy Krieger Institute;|Jane E. Roberts, University of South Carolina;|Nancy C. Brady, University of Kansas;|Samuel D. McQuillin, University of Houston; and.|Steven F. Warren, University of Kansas.
authors.forename: Steven F
authors.initials: SF
authors.lastname: Warren
mesh_terms: D000328:Adult; D002675:Child, Preschool; D005260:Female; D005600:Fragile X Syndrome; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis; D007223:Infant; D008297:Male; D009035:Mothers / Q000523:psychology*; D016487:Parenting / Q000523:psychology*; D000066553:Problem Behavior; D012463:Saliva / Q000737:chemistry; D013312:Stress, Physiological; D013315:Stress, Psychological / Q000523:psychology*
chemical_list: D006854:Hydrocortisone
keywords: Fragile X syndrome; maternal responsivity; parenting behaviors; physiological arousal; salivary cortisol