title: Cardiac biomarkers in premature calves with respiratory distress syndrome.
abstract: The aim of this study was to determine the clinical relevance of cardiac biomarkers [troponin I and T, creatine kinase-MB fraction (CK-MB) and lactate dehydrogenase (LDH)] in premature calves with respiratory distress syndrome. Seventy premature calves were admitted to the clinic within 24 h after birth. Respiratory distress syndrome was diagnosed in premature calves by clinical examination and venous blood gas analysis. Ten healthy calves, aged 5 days, were used as control. Cardiac troponin I and T were analysed using ELISA and ELFA, respectively. Serum CK-MB and LDH were also analysed in an automatic analyser. The calves had low venous pH, pO2, O2 saturation and high pCO2 values consistent with dyspnoea, hypoxaemia, and inadequate oxygen delivery. Mean serum troponin I, troponin T, CK-MB and LDH levels were increased in the premature calves compared to the control group. In conclusion, the results in this study demonstrated that serum CK-MB, troponin I and troponin T concentrations could be used for evaluating myocardial injury in premature calves with respiratory distress syndrome.
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Cumhuriyet University , Sivas , Turkey.
authors.forename: Ugur
authors.initials: U
authors.lastname: Aydogdu
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Mehmet Akif Ersoy University , Burdur , Turkey.
authors.forename: Ramazan
authors.initials: R
authors.lastname: Yildiz
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Kyrgyz Turkish Manas University , Bishkek , Kyrgyzstan.|Department of Internal Medicine, Faculty of Veterinary Medicine, Selcuk University , 42075 Konya , Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Guzelbektes
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Cumhuriyet University , Sivas , Turkey.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Coskun
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Selcuk University , 42075 Konya , Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Sen
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D015415:Biomarkers / Q000378:metabolism; D001784:Blood Gas Analysis / Q000662:veterinary; D002417:Cattle; D002418:Cattle Diseases / Q000378:metabolism*; D052279:Creatine Kinase, MB Form / Q000378:metabolism; D012127:Respiratory Distress Syndrome, Newborn / Q000378:metabolism / Q000662:veterinary*; D019210:Troponin I / Q000378:metabolism; D020107:Troponin T / Q000378:metabolism
chemical_list: D015415:Biomarkers; D019210:Troponin I; D020107:Troponin T; D052279:Creatine Kinase, MB Form
keywords: Premature calves; cardiac biomarkers; respiratory distress syndrome