title: Comparison of lidocaine spray and paracervical block application for pain relief during first-trimester surgical abortion: A randomised, double-blind, placebo-controlled trial.
abstract: Surgical abortion is one of the most frequently performed gynaecological procedures and its associated pain has always been a problem in gynaecology. Here we studied the analgesic efficacy of lidocaine spray and paracervical block (PCB) in patients undergoing first-trimester surgical abortion. A randomised double-blind placebo-controlled study was conducted on 108 women requesting pregnancy termination. The subjects were randomly assigned into four groups: Group 1 (PCB plus lidocaine spray) (n=27), Group 2 (PCB) (n=27), Group 3 (lidocaine spray) (n=27) and Group 4 (placebo) (n=27). Intra-procedural and post-procedural pain scores were measured with a standard visual analogue scale (VAS). The median VAS scores during procedure in placebo, lidocaine spray, PCB plus lidocaine spray and PCB groups were 8 (7-9), 5 (4-8), 4 (3-4) and 5 (3-5), respectively. The most effective method of pain relief during first-trimester abortion can be achieved through a combined use of PCB plus lidocaine spray. Therefore, lidocaine spray is a non-invasive complementary anaesthetic method versus traditional PCB for first-trimester surgical abortion.
authors.affiliation: a Department of Obstetrics and Gynaecology , Kayseri Military Hospital , Kayseri , Turkey .
authors.forename: Huseyin
authors.initials: H
authors.lastname: Aksoy
authors.affiliation: b Department of Obstetrics and Gynaecology , Kayseri Memorial Hospital , Kayseri , Turkey .
authors.forename: Ulku
authors.initials: U
authors.lastname: Aksoy
authors.affiliation: c Department of Obstetrics and Gynaecology , Kayseri Education and Research Hospital of Medicine , Kayseri , Turkey .
authors.forename: Sezin
authors.initials: S
authors.lastname: Ozyurt
authors.affiliation: d Department of Family Planning , Kayseri Education and Research Hospital of Medicine , Kayseri , Turkey .
authors.forename: Nil
authors.initials: N
authors.lastname: Ozoglu
authors.affiliation: c Department of Obstetrics and Gynaecology , Kayseri Education and Research Hospital of Medicine , Kayseri , Turkey .
authors.forename: Gokhan
authors.initials: G
authors.lastname: Acmaz
authors.affiliation: e Department of Obstetrics and Gynaecology , Kayseri Acıbadem Hospital , Kayseri , Turkey , and.
authors.forename: Turgut
authors.initials: T
authors.lastname: Aydın
authors.affiliation: e Department of Obstetrics and Gynaecology , Kayseri Acıbadem Hospital , Kayseri , Turkey , and.
authors.forename: Özge
authors.initials: Ö
authors.lastname: İdem Karadağ
authors.affiliation: f Department of Obstetrics and Gynaecology , Private Erciyes Hospital , Kayseri , Turkey.
authors.forename: Ahter Tanay
authors.initials: AT
authors.lastname: Tayyar
mesh_terms: D000028:Abortion, Induced / Q000009:adverse effects* / Q000379:methods; D000328:Adult; D000773:Anesthesia, Obstetrical / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D003131:Combined Modality Therapy; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007431:Intraoperative Complications / Q000188:drug therapy*; D008012:Lidocaine / Q000008:administration & dosage*; D010146:Pain / Q000188:drug therapy* / Q000209:etiology; D010147:Pain Measurement; D011247:Pregnancy; D011261:Pregnancy Trimester, First; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine
keywords: Analgesia; lidocaine spray; paracervical block; surgical abortion