title: The expanding indications of transcatheter aortic valve implantation.
abstract: Transcatheter aortic valve implantation (TAVI), also known as transcatheter aortic valve replacement, is increasingly performed worldwide and is a technology that is here to stay. It has become the treatment of choice for inoperable patients and an alternative option for patients at high surgical risk with severe aortic stenosis. Early results of TAVI in intermediate-risk patients appear promising although larger randomized trial results are awaited before the widespread adoption of this technology in this big pool of patients. In patients with bicuspid aortic stenosis and degenerated surgical bioprostheses, TAVI has been shown to be feasible and relatively safe, though certain important considerations remain. Indications for TAVI are likely to grow as newer generation and improved devices and delivery systems become available.
authors.affiliation: The Heart & Vascular Centre, Mount Elizabeth Hospital, 3 Mount Elizabeth, 228510, Singapore.|National University of Singapore, Yong Loo Lin School of Medicine, 1E Kent Ridge Rd 119228, NUHS Tower Block, Level 11, 117597, Singapore.
authors.forename: Paul T L
authors.initials: PT
authors.lastname: Chiam
authors.affiliation: Department of Cardiology, National Heart Centre, 5 Hospital Dr, 169609, Singapore.
authors.forename: See Hooi
authors.initials: SH
authors.lastname: Ewe
mesh_terms: D001024:Aortic Valve Stenosis / Q000601:surgery*; D001705:Bioprosthesis; D006350:Heart Valve Prosthesis; D006801:Humans; D018579:Patient Selection; D065467:Transcatheter Aortic Valve Replacement
keywords: aortic regurgitation; aortic valve stenosis; bicuspid aortic valve; bioprosthesis; heart valve prosthesis implantation; transcatheter aortic valve implantation; transcatheter aortic valve replacement