title: [The association between red cell distribution width (RDW) and short-term mortality risk in patients with acute coronary syndrome (ACS)].
abstract: OBJECTIVE
  To demonstrate the association between red cell distribution width and short-term mortality risk in patients with acute coronary syndrome.
  
  
  METHODS
  We prospectively recruited 78 patients with acute coronary syndrome. The study population was classified according to quartiles of the red cell distribution width at hospital admission. A high red cell distribution width was defined as a value in the upper fourth quartile (>15) and a low red cell distribution width was defined as any value set in the lower three quartiles (≤15). After discharge, all patients were followed for three months.
  
  
  RESULTS
  The short-term cardiovascular mortality was 47.2% in the high red cell distribution width group vs. 10.2% in the low red cell distribution width group (p<0.001). In the receiver operating characteristic curve analysis, a red cell distribution width value of more than 15% yielded a sensitivity of 66.7%, a specificity of 83%, and a positive predictive value of 79.7% for cardiac mortality. After multivariate analysis, high levels of red cell distribution width were independent predictors for three-month mortality (p=0.001).
  
  
  CONCLUSIONS
  We demonstrated that red cell distribution width is an accessible parameter associated with short-term cardiovascular mortality in patients with acute coronary syndrome.
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., México.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Rosas-Cabral
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., México.
authors.forename: Jesús Antonio
authors.initials: JA
authors.lastname: Viana-Rojas
authors.affiliation: Servicio de Medicina Crítica, Hospital General de Zona N.o 1, IMSS, Aguascalientes, Ags., México.
authors.forename: Jorge
authors.initials: J
authors.lastname: Prieto-Macías
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., México.
authors.forename: María
authors.initials: M
authors.lastname: del Carmen Terrones-Saldívar
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., México.
authors.forename: Rafael
authors.initials: R
authors.lastname: Gutiérrez-Campos
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., México.
authors.forename: Silvia Denise
authors.initials: SD
authors.lastname: Ponce-Campos
authors.affiliation: Departamento de Medicina, Universidad Autónoma de Aguascalientes, Aguascalientes, Ags., México.
authors.forename: José
authors.initials: J
authors.lastname: de Jesús de Lara-Castañeda
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood* / Q000401:mortality*; D000368:Aged; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012307:Risk Factors; D013997:Time Factors