title: Properly dividing with YAP.
abstract: The Hippo pathway prevents organ overgrowth and maintains tissue architecture by inhibiting the transcriptional coactivator YAP. In this issue of Science Signaling, Bui et al. find a role for YAP during cytokinesis that is independent of its transcriptional activity. This function of YAP may be important for maintaining genomic stability in dividing cells.
authors.affiliation: Center for Epigenetics, Van Andel Research Institute, Grand Rapids, MI 49503, USA. gerd.pfeifer@vai.org.
authors.forename: Gerd P
authors.initials: GP
authors.lastname: Pfeifer
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism; D006801:Humans; D010750:Phosphoproteins / Q000378:metabolism; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*; D015398:Signal Transduction; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D010750:Phosphoproteins; D014157:Transcription Factors; D017346:Protein Serine-Threonine Kinases