title: Randomized Double-blind Clinical Trial of Bleaching Products in Patients Wearing Orthodontic Devices.
abstract: OBJECTIVE
  This double-blind randomized clinical trial evaluated tooth sensitivity (TS) and the effectiveness (EF) of two types of bleaching agents (Trèswhite Ortho [TWO] and Trèswhite Supreme [TWS]) when used in patients wearing orthodontic appliances.
  
  
  METHODS
  Forty patients between the ages of 18 and 40 years were randomly stratified, with an equal allocation rate, into two groups (n=20), according to the bleaching agent applied. Tooth color of the six maxillary anterior teeth was measured before and after the treatment with a spectrophotometer. The TS was recorded on three scales before and during the bleaching treatment.
  
  
  RESULTS
  With regard to EF, a significant reduction was found (ranging from 7.3-9.6 and 5.3-9.5 Vita scale units for TWO and TWS, respectively, p<0.001); however, there was no statistical difference between the groups (p>0.63). The number of patients with sensitivity was 58.8% and 73.3% for TWO and TWS groups, respectively (p=0.53); however, with each of the three scales used, the intensity of sensitivity was low and there was no statistical difference between TWO and TWS (p>0.05).
  
  
  CONCLUSIONS
  In spite of producing a side effect of low TS, the two bleaching treatments tested were effective for dental bleaching in patients with fixed orthodontic appliances.
authors.forename: A
authors.initials: A
authors.lastname: Montenegro-Arana
authors.forename: L A
authors.initials: LA
authors.lastname: Arana-Gordillo
authors.forename: D
authors.initials: D
authors.lastname: Farana
authors.forename: A
authors.initials: A
authors.lastname: Davila-Sanchez
authors.forename: E
authors.initials: E
authors.lastname: Jadad
authors.forename: U
authors.initials: U
authors.lastname: Coelho
authors.forename: Omm
authors.initials: O
authors.lastname: Gomes
authors.forename: A D
authors.initials: AD
authors.lastname: Loguercio
mesh_terms: D000293:Adolescent; D000328:Adult; D003807:Dentin Sensitivity; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009967:Orthodontic Appliances; D014073:Tooth Bleaching; D058205:Tooth Bleaching Agents / Q000494:pharmacology*; D055815:Young Adult
chemical_list: D058205:Tooth Bleaching Agents