title: A new benzopyrans derivatives from a mangrove-derived fungus Penicillium citrinum from the South China Sea.
abstract: One new benzopyran derivative (2R(*),4R(*))-3,4-dihydro-5-methoxy-2-methyl-2H-1-benzopyran-4-ol (1), together with five known compounds (2-6), were obtained from the EtOAc extract of the endophytic fungus Penicillium citrinum HL-5126 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their antibacterial activities. Compound 6 exhibited potent inhibitory activity against Bacillus subtilis, Bacillus cereus and Micrococcus tetragenus with the same MIC values of 6.94 μM.
authors.affiliation: a Guangxi Key Laboratory of Marine Biotechnology , Guangxi Institute of Oceanology , Beihai , China.
authors.forename: Cai-Juan
authors.initials: CJ
authors.lastname: Zheng
authors.affiliation: a Guangxi Key Laboratory of Marine Biotechnology , Guangxi Institute of Oceanology , Beihai , China.
authors.forename: Guo-Lei
authors.initials: GL
authors.lastname: Huang
authors.affiliation: b Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Xu
authors.affiliation: a Guangxi Key Laboratory of Marine Biotechnology , Guangxi Institute of Oceanology , Beihai , China.
authors.forename: Xin-Ming
authors.initials: XM
authors.lastname: Song
authors.affiliation: a Guangxi Key Laboratory of Marine Biotechnology , Guangxi Institute of Oceanology , Beihai , China.
authors.forename: Jun
authors.initials: J
authors.lastname: Yao
authors.affiliation: a Guangxi Key Laboratory of Marine Biotechnology , Guangxi Institute of Oceanology , Beihai , China.
authors.forename: Hui
authors.initials: H
authors.lastname: Liu
authors.affiliation: a Guangxi Key Laboratory of Marine Biotechnology , Guangxi Institute of Oceanology , Beihai , China.
authors.forename: Ruo-Ping
authors.initials: RP
authors.lastname: Wang
authors.affiliation: b Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
authors.forename: Xue-Ping
authors.initials: XP
authors.lastname: Sun
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification*; D001578:Benzopyrans / Q000737:chemistry / Q000302:isolation & purification*; D002681:China; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry*; D043982:Rhizophoraceae / Q000382:microbiology*; D013057:Spectrum Analysis
chemical_list: D000900:Anti-Bacterial Agents; D001578:Benzopyrans
keywords: Penicillium citrinum; antibacterial activity; benzopyran derivative; metabolites