title: High-frequency ventilation for non-invasive respiratory support of neonates.
abstract: Non-invasive respiratory support is increasingly used in lieu of intubated ventilator support for the management of neonatal respiratory failure, particularly in very low birth weight infants at risk for bronchopulmonary dysplasia. The optimal approach and mode for non-invasive support remains uncertain. This article reviews the application of high-frequency ventilation for non-invasive respiratory support in neonates, including basic science studies on mechanics of gas exchange, animal model investigations, and a review of current clinical use in human neonates.
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: bradley.yoder@hsc.utah.edu.
authors.forename: Bradley A
authors.initials: BA
authors.lastname: Yoder
authors.affiliation: Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA.
authors.forename: K H
authors.initials: KH
authors.lastname: Albertine
authors.affiliation: Department of Pediatrics, University of California at Davis, Sacramento, CA, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Null
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000628:therapy*; D006612:High-Frequency Ventilation / Q000379:methods*; D006801:Humans; D007231:Infant, Newborn; D063087:Noninvasive Ventilation / Q000379:methods*; D012131:Respiratory Insufficiency / Q000628:therapy*
keywords: High frequency; Neonatal; Non-invasive; Respiratory