title: A Novel Approach for Computer-Assisted Template-Guided Autotransplantation of Teeth With Custom 3D Designed/Printed Surgical Tooling. An Ex Vivo Proof of Concept.
abstract: OBJECTIVE
  The aim of this study was to introduce a novel method for accurate autotransplantation with computer-assisted guided templates and assembled custom-designed surgical tooling and to test the feasibility and accuracy of this method ex vivo.
  
  
  METHODS
  A partially edentulous human mandibular cadaver was scanned with a cone-beam computed tomography (CBCT) system and an intraoral scan system. The 3-dimensional (3D) data of this cadaver were imported into specialized software and used to analyze the region of the recipient site and the donor tooth was selected. Subsequently, congruent to the donor tooth, custom surgical tools and a surgical guided template were designed and 3D printed. The guided osteotomy was performed and the donor tooth was transplanted. To evaluate the planned position of the donor tooth in relation to the position of the transplanted donor tooth, the mandible with the transplanted donor tooth was rescanned with the CBCT system and software matching was applied to measure the accuracy of the procedure.
  
  
  RESULTS
  The angular deflection of the transplanted donor tooth in relation to the planned donor tooth position was 3.1°. When comparing the 3D positions of the shoulder, there was a deviation of 1.25 mm and an apical deviation of 0.89 mm.
  
  
  CONCLUSIONS
  With the use of currently available technology, it is feasible to accurately plan and create in a virtual simulation a donor tooth position with congruent custom surgical tools and to transfer this to a clinical setting with 3D printing. However, further research on multiple levels is needed to explore this novel approach.
authors.affiliation: PhD Resident, Department of Oral Implantology and Prosthetic Dentistry, Academic Center for Dentistry Amsterdam (ACTA), Research Institute Move, Amsterdam, The Netherlands. Electronic address: danssari@acta.nl.
authors.forename: David
authors.initials: D
authors.lastname: Anssari Moin
authors.affiliation: PhD Resident, Department of Oral Implantology and Prosthetic Dentistry, Academic Center for Dentistry Amsterdam (ACTA), Research Institute Move, Amsterdam, The Netherlands.
authors.forename: Wiebe
authors.initials: W
authors.lastname: Derksen
authors.affiliation: PhD resident, Department of Oral and Maxillofacial Surgery, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: J P
authors.initials: JP
authors.lastname: Verweij
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, Leiden University Medical Center, Leiden, The Netherlands.
authors.forename: Richard
authors.initials: R
authors.lastname: van Merkesteyn
authors.affiliation: Professor, Department of Oral Implantology and Prosthetic Dentistry, Academic Center for Dentistry Amsterdam (ACTA), Research Institute Move, Amsterdam, The Netherlands.
authors.forename: Daniel
authors.initials: D
authors.lastname: Wismeijer
mesh_terms: D054893:Cone-Beam Computed Tomography / Q000379:methods; D003758:Dental Implantation, Endosseous / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D008334:Mandible / Q000000981:diagnostic imaging; D066330:Printing, Three-Dimensional; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014070:Tooth / Q000000981:diagnostic imaging / Q000637:transplantation*