title: Relationship Between Pathological Findings and Cholinesterase Activity and Nitric Oxide Levels in Cattle Infected Naturally by Eurytrema coelomaticum.
abstract: The aim of this study was to evaluate the role of butyrylcholinesterase (BChE) (in the serum and pancreas), acetylcholinesterase (AChE) (in the whole blood and pancreas) and nitric oxide (NO) (in the serum and pancreas) in cattle infected naturally by Eurytrema coelomaticum. Fifty-one cattle were studied, including 33 infected by E. coelomaticum and 18 uninfected animals. Significantly greater AChE activity was found in the pancreas of infected animals (P <0.01); however, these cattle had lower AChE activity in whole blood. BChE activity was greater in the sera of infected animals (P = 0.05), but was less in pancreatic samples. NO levels were significantly higher in the sera (P <0.05) and pancreas (P <0.001) of infected cattle compared with uninfected animals. A positive correlation was found between AChE activity in the pancreas and parasite load, but there was negative correlation between pancreatic BChE activity and parasitic load. Expression of AChE, BChE and NO is therefore linked to the inflammation caused by E. coelomaticum in cattle.
authors.affiliation: Laboratory of Veterinary Pathology, Instituto Federal Catarinense, Concórdia, Santa Catarina, Brazil.
authors.forename: C I
authors.initials: CI
authors.lastname: Schwertz
authors.affiliation: Department of Biochemistry and Molecular Biology, Brazil.
authors.forename: G M
authors.initials: GM
authors.lastname: do Carmo
authors.affiliation: Department of Biochemistry and Molecular Biology, Brazil.
authors.forename: N B
authors.initials: NB
authors.lastname: Bottari
authors.affiliation: Laboratory of Veterinary Pathology, Instituto Federal Catarinense, Concórdia, Santa Catarina, Brazil.
authors.forename: E S
authors.initials: ES
authors.lastname: da Silva
authors.affiliation: Laboratory of Veterinary Pathology, Instituto Federal Catarinense, Concórdia, Santa Catarina, Brazil.
authors.forename: M E
authors.initials: ME
authors.lastname: Gabriel
authors.affiliation: Laboratory of Veterinary Pathology, Instituto Federal Catarinense, Concórdia, Santa Catarina, Brazil.
authors.forename: N J
authors.initials: NJ
authors.lastname: Lucca
authors.affiliation: Department of Clinical and Toxicological Analyses, Universidade Federal de Santa Maria, Santa Maria, Brazil.
authors.forename: N dos S
authors.initials: Ndos S
authors.lastname: Guarda
authors.affiliation: Department of Clinical and Toxicological Analyses, Universidade Federal de Santa Maria, Santa Maria, Brazil.
authors.forename: R N
authors.initials: RN
authors.lastname: Moresco
authors.affiliation: College of Veterinary Medicine, Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: G
authors.initials: G
authors.lastname: Machado
authors.affiliation: Department of Biochemistry and Molecular Biology, Brazil.
authors.forename: V M
authors.initials: VM
authors.lastname: Morsch
authors.affiliation: Department of Biochemistry and Molecular Biology, Brazil.
authors.forename: M R C
authors.initials: MR
authors.lastname: Schetinger
authors.affiliation: Department of Animal Science, Universidade do Estado de Santa Catarina, Chapecó, Brazil.
authors.forename: L M
authors.initials: LM
authors.lastname: Stefani
authors.affiliation: Laboratory of Veterinary Pathology, Instituto Federal Catarinense, Concórdia, Santa Catarina, Brazil. Electronic address: ricardo.mendes@ifc-concordia.edu.br.
authors.forename: R E
authors.initials: RE
authors.lastname: Mendes
authors.affiliation: Department of Animal Science, Universidade do Estado de Santa Catarina, Chapecó, Brazil. Electronic address: aleksandro_ss@yahoo.com.br.
authors.forename: A S
authors.initials: AS
authors.lastname: Da Silva
mesh_terms: D000110:Acetylcholinesterase / Q000032:analysis / Q000378:metabolism*; D000818:Animals; D002091:Butyrylcholinesterase / Q000032:analysis / Q000378:metabolism*; D002417:Cattle; D002418:Cattle Diseases / Q000378:metabolism / Q000382:microbiology*; D009569:Nitric Oxide / Q000032:analysis / Q000378:metabolism*; D014201:Trematode Infections / Q000378:metabolism / Q000662:veterinary*
chemical_list: D009569:Nitric Oxide; D000110:Acetylcholinesterase; D002091:Butyrylcholinesterase
keywords: acetylcholinesterase; butyrylcholinesterase; eurytrematosis; nitric oxide