title: Efficient continuous synthesis of high purity deep eutectic solvents by twin screw extrusion.
abstract: Mechanochemical synthesis has been applied to the rapid synthesis of Deep Eutectic Solvents (DESs), including Reline 200 (choline chloride : urea, 1 : 2), in a continuous flow methodology by Twin Screw Extrusion (TSE). This gave products in higher purity and with Space Time Yields (STYs), four orders of magnitude greater than for batch methods.
authors.affiliation: School of Chemistry and Chemical Engineering, Queen's University Belfast, 39 - 123 Stranmillis Road, Belfast, BT9 5AG, Northern Ireland, UK. s.james@qub.ac.uk.
authors.forename: D E
authors.initials: DE
authors.lastname: Crawford
authors.affiliation: Department of Chemistry, University of Leicester, Leicester, LE1 7RH, UK. apa1@le.ac.uk.
authors.forename: L A
authors.initials: LA
authors.lastname: Wright
authors.affiliation: School of Chemistry and Chemical Engineering, Queen's University Belfast, 39 - 123 Stranmillis Road, Belfast, BT9 5AG, Northern Ireland, UK. s.james@qub.ac.uk.
authors.forename: S L
authors.initials: SL
authors.lastname: James
authors.affiliation: Department of Chemistry, University of Leicester, Leicester, LE1 7RH, UK. apa1@le.ac.uk.
authors.forename: A P
authors.initials: AP
authors.lastname: Abbott