title: The Prevalence of Dry Eye and Sjögren Syndrome in Patients with Migraine.
abstract: OBJECTIVE
  To evaluate the presence of dry eye and primary Sjögren syndrome (SS) in patients with migraine.
  
  
  METHODS
  In total, 46 eyes of 46 patients with migraine (group 1) and 50 eyes of 50 healthy subjects (group 2) were included in this study. Detailed ophthalmologic, neurologic and rheumatologic examination were performed on all participants. Ocular surface disease index questionnaire, tear function tests, visual analog scale for pain, serologic analysis were also performed.
  
  
  RESULTS
  Dry eye symptoms and findings were significantly higher and more severe in group 1 when compared with group 2. Primary SS was not found in any of the participants. The migraine lifetime duration was negatively correlated with the tear function tests while it was positively correlated with the ocular surface disease index scores.
  
  
  CONCLUSIONS
  Dry eye symptoms and findings are higher in migraine patients when compared with the healthy subjects without the presence of Sjögren syndrome.
authors.affiliation: a Department of Ophthalmology , Yildirim Beyazit University Atatürk Research and Training Hospital , Ankara , Turkey.
authors.forename: Ozge
authors.initials: O
authors.lastname: Sarac
authors.affiliation: b Department of Ophthalmology , Ulucanlar Eye Research and Training Hospital , Ankara , Turkey.
authors.forename: Pinar
authors.initials: P
authors.lastname: Kosekahya
authors.affiliation: c Department of Ophthalmology , Special Maya Eye Clinic , Ankara , Turkey.
authors.forename: Yelda
authors.initials: Y
authors.lastname: Yildiz Tasci
authors.affiliation: d Department of Neurology , Yildirim Beyazit University Atatürk Research and Training Hospital , Ankara , Turkey.
authors.forename: Hava D
authors.initials: HD
authors.lastname: Keklikoglu
authors.affiliation: d Department of Neurology , Yildirim Beyazit University Atatürk Research and Training Hospital , Ankara , Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Deniz
authors.affiliation: e Department of Rheumatology , Yildirim Beyazit University Atatürk Research and Training Hospital , Ankara , Turkey.
authors.forename: Şükran
authors.initials: Ş
authors.lastname: Erten
authors.affiliation: a Department of Ophthalmology , Yildirim Beyazit University Atatürk Research and Training Hospital , Ankara , Turkey.
authors.forename: Nurullah
authors.initials: N
authors.lastname: Çağıl
mesh_terms: D000328:Adult; D015352:Dry Eye Syndromes / Q000145:classification / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008881:Migraine Disorders / Q000453:epidemiology*; D015995:Prevalence; D011446:Prospective Studies; D012859:Sjogren's Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D013666:Tears / Q000502:physiology; D014421:Turkey / Q000453:epidemiology
keywords: Dry eye; Sjögren syndrome; migraine