title: Antioxidant potential in non-extractable fractions of dried persimmon (Diospyros kaki Thunb.).
abstract: Dried fruits of persimmon (Diospyros kaki Thunb.) are a traditional food in Japan and contain large quantities of tannins. In this study, we investigated the in vitro and in vivo antioxidant potentials of non-extractable fractions from dried persimmons. Hydrolysed non-extractable fractions showed the highest antioxidant activities in vitro. In subsequent experiments, the plasma oxygen radical absorbance capacity (ORAC) values in rats supplemented with a 5% non-extractable fraction were approximately 1.5times higher than those in control rats after 1week in vivo. Furthermore, using an in vitro model of the gastrointestinal tract, the ORAC values of the non-extractable fraction were significantly increased with colonic fermentation in the large bowel stage. These data indicate that non-extractable fractions may possess significant antioxidant potential in vitro and in vivo.
authors.affiliation: Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan; Department of Immunology, Nara Medical University, 840 Shijo-cho, Kashihara-City, Nara 634-8521, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Matsumura
authors.affiliation: Department of Immunology, Nara Medical University, 840 Shijo-cho, Kashihara-City, Nara 634-8521, Japan.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ito
authors.affiliation: Department of Microbiology and Infectious Diseases, Nara Medical University, 840 Shijo-cho, Kashihara-City, Nara 634-8521, Japan.
authors.forename: Hisakazu
authors.initials: H
authors.lastname: Yano
authors.affiliation: Nara City Hospital, 1-50-1 Higashikidera, Nara-City, Nara 630-8305, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Kita
authors.affiliation: Center for Infectious Diseases, Nara Medical University, 840 Shijo-cho, Kashihara-City, Nara 634-8521, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Mikasa
authors.affiliation: Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Okada
authors.affiliation: Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan.
authors.forename: Azusa
authors.initials: A
authors.lastname: Furutani
authors.affiliation: Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Murono
authors.affiliation: Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan.
authors.forename: Mitsuru
authors.initials: M
authors.lastname: Shibata
authors.affiliation: Department of Physical Therapy, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan.
authors.forename: Yasue
authors.initials: Y
authors.lastname: Nishii
authors.affiliation: Department of Health and Nutrition, Faculty of Health Science, Kio University, 4-2-2 Umaminaka, Koryo-cho, Kitakatsuragi-gun, Nara 635-0832, Japan. Electronic address: s.kayano@kio.ac.jp.
authors.forename: Shin-Ichi
authors.initials: S
authors.lastname: Kayano
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D029788:Diospyros; D005638:Fruit; D008297:Male; D010936:Plant Extracts / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar
chemical_list: D000975:Antioxidants; D010936:Plant Extracts
keywords: Antioxidant activity; Model of the gastrointestinal tract; Oxygen radical absorbance capacity; Persimmon