title: [Review of ear and nose and throat involvement in IgG4-RD].
abstract: IgG4-related disease (IgG4-RD) is a newly recognized disease entity. IgG4-RD is characterized by a single or multiple masses in one or more organs; a lymphoplasmacytic infiltrate with a high percentage of plasma cells within the lesion staining for IgG4; a peculiar pattern of fibrosis known as "storiform" fibrosis; and elevated serum IgG4 concentrations. IgG4-RD can occur in various organs, including pancreas, kidneys, lungs, retroperitoneum, and prostate gland. The head and neck involvements of IgG4-RD have been chiefly described in Mikulicz disease (MD), Küttner's tumor, orbital? inflammatory pseudotumor, and idiopathic hypertrophic pachymeningitis (IHP) previously. Recent studies reported that IgG4-RD could also involve ear, nose and throat. Here we reviewed the literatures about ear, nose and throat involvement by IgG4-RD, in order to provide some theoretical bases for the diagnosis and treatment of IgG4-RD.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Tao
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Bo
authors.initials: B
authors.lastname: Song
mesh_terms: D001327:Autoimmune Diseases / Q000503:physiopathology*; D004423:Ear / Q000503:physiopathology*; D005355:Fibrosis; D006801:Humans; D007074:Immunoglobulin G; D009666:Nose / Q000503:physiopathology*; D010614:Pharynx / Q000503:physiopathology*; D010950:Plasma Cells / Q000473:pathology*
chemical_list: D007074:Immunoglobulin G