title: [Study on Serological Blood Group Conversion in BM Empty Phase of ABO-incompatible Allogeneic Stem Cell Transplantation].
abstract: OBJECTIVE
  To explore the regularity of serological conversion of blood group in BM empty phase of ABO-incompatible allogeneic stem cell transplantation so as to provide the basis for selecting the blood components in blood transfusion.
  
  
  METHODS
  Before hematpoietic stem cell transplantation (HSCT), the ABO and RhD blood groups of recipients and donors were identified by salt medium tube method and microcolumn gel method; after transplantation the changes of antigen intensity and antibody titer of ABO blood group in patients were periodically detected.
  
  
  RESULTS
  After blood group shift of 33 patients received ABO-incompatible allo-HSCT, the consistent rate of positive and regative types in major ABO incompatible group was 100%; the consistent rate of positive and negative types in minor ABO-incompatible group was 33%, no-consistent rate was 66.7%; the consistent rate of positive and negative types in bidirextional ABO incompatible group was 20%, the no-consistent rate was 80%.
  
  
  CONCLUSIONS
  After ABO-incompatible allo-HSCT, blood group antgen of patients shifts to the blood group of donors, there is a significant difference in the serological indicators between the minor and bidireetional ABO-incompatible patients and normal people.
authors.affiliation: Department of Blood Transfusion, The First Affiliate Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang Province, China. E-mail: 942118013@qq.com.
authors.forename: Xue-Jiao
authors.initials: XJ
authors.lastname: Cai
authors.affiliation: Department of Blood Transfusion, The First Affiliate Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Bi-Le
authors.initials: BL
authors.lastname: Chen
authors.affiliation: Department of Blood Transfusion, The First Affiliate Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Zuo-Ting
authors.initials: ZT
authors.lastname: Xie
authors.affiliation: Department of Blood Transfusion, The First Affiliate Hospital of Wenzhou Medical College, Wenzhou 325000, Zhejiang Province, China.
authors.forename: Yin-Cai
authors.initials: YC
authors.lastname: Ye
mesh_terms: D000017:ABO Blood-Group System; D001787:Blood Group Incompatibility; D001803:Blood Transfusion; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D014019:Tissue Donors; D014184:Transplantation, Homologous
chemical_list: D000017:ABO Blood-Group System