title: Impact of Transcatheter Aortic Valve Replacement on Surgical Volumes and Outcomes in a Tertiary Academic Cardiac Surgical Practice.
abstract: BACKGROUND
  Transcatheter aortic valve replacement (TAVR) was FDA approved for the Sapien valve (Edwards Lifesciences) in the United States in November 2011. We sought to examine the impact of TAVR post-FDA approval on aortic valve surgery at our institution.
  
  
  METHODS
  Prospective data were collected on 573 consecutive patients that underwent surgical aortic valve replacement (SAVR) or TAVR with either the Sapien or Sapien XT from January 1, 2009 through December 31, 2014.
  
  
  RESULTS
  Patients were divided into the following groups: SAVR before TAVR (n = 215), SAVR post TAVR (n = 163), and TAVR (n = 195). The 30-day mortality was not different among the 3 groups, but the mortality for the SAVR post TAVR group was better than the SAVR before TAVR group (p = 0.03). Postoperative hospital length of stay, ventilation hours, and atrial fibrillation were all decreased in the TAVR group. The number of isolated SAVRs increased after TAVR from 60 per year in group 1 to 67 per year in group 2. The total number of all isolated aortic valve procedures (SAVR + TAVR) increased from 60 per year to 177 per year. The TAVR group was divided into the following subgroups to examine the procedural learning curve: patients 1 to 50, patients 51 to 100, and patients 101 to 195. Mortality was higher in group 1 (8%) vs group 2 (0%) and group 3 (1%).
  
  
  CONCLUSIONS
  Since initiation of the TAVR program at our institution, the total number of aortic valve procedures has increased. Transcatheter aortic valve replacement patients had more preoperative comorbidities, but no difference in postoperative morbidity or mortality and shorter length of stay. Transcatheter aortic valve replacement mortality has continued to improve since the inception of the program.
authors.affiliation: Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL. Electronic address: jdavies@uabmc.edu.
authors.forename: James E
authors.initials: JE
authors.lastname: Davies
authors.affiliation: Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: William W
authors.initials: WW
authors.lastname: McAlexander
authors.affiliation: Division of Cardiovascular Services, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: Mark F
authors.initials: MF
authors.lastname: Sasse
authors.affiliation: Division of Cardiovascular Services, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: Massoud A
authors.initials: MA
authors.lastname: Leesar
authors.affiliation: Division of Cardiothoracic Surgery, Washington University, St Louis, MO.
authors.forename: Spencer J
authors.initials: SJ
authors.lastname: Melby
authors.affiliation: Department of Radiology, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: Satinder P
authors.initials: SP
authors.lastname: Singh
authors.affiliation: Division of Cardiothoracic Surgery, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: Lindsey B
authors.initials: LB
authors.lastname: Jernigan
authors.affiliation: Division of Cardiovascular Services, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: Oscar J
authors.initials: OJ
authors.lastname: Booker
authors.affiliation: Division of Cardiovascular Services, University of Alabama at Birmingham, Birmingham, AL.
authors.forename: Oluseun O
authors.initials: OO
authors.lastname: Alli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D062606:Tertiary Care Centers; D065467:Transcatheter Aortic Valve Replacement / Q000706:statistics & numerical data*; D016896:Treatment Outcome