title: Bovine dopamine receptors DRD1, DRD4, and DRD5: genetic polymorphisms and diversities among ten cattle breeds.
abstract: The aim of this study was to analyze the allelic frequency distribution and segregation among breeds and/or between different cattle genetic groups of four novel single nucleotide polymorphisms of the bovine DRD1 and DRD5 genes and one reported SNP from the DRD4 gene. One hundred and nine-animals from ten different cattle breeds were genotyped and allelic frequencies for each locus were estimated. There were significant differences in the allelic frequencies (P < 0.05) among breeds for the DRD1 and DRD5 markers. The allelic frequencies for markers DRD1-825A>G and DRD5-378C>T were also significantly different between groups differing in genetic background. Because differences in temperament have been reported between Bos taurus taurus and B. taurus indicus breeds and their crosses, further studies are needed to investigate if any association exists between described markers and cattle behavior traits.
authors.affiliation: Centro de Biotecnología Genómica-Instituto Politécnico Nacional, Colonia Narciso Mendoza, Reynosa, Tamaulipas, México.
authors.forename: A M
authors.initials: AM
authors.lastname: Sifuentes-Rincón
authors.affiliation: Centro de Biotecnología Genómica-Instituto Politécnico Nacional, Colonia Narciso Mendoza, Reynosa, Tamaulipas, México.
authors.forename: A G
authors.initials: AG
authors.lastname: Trejo-Tapia
authors.affiliation: Texas AgriLife Research, Texas A&M System, Overton, TX, USA.
authors.forename: R D
authors.initials: RD
authors.lastname: Randel
authors.affiliation: Centro de Biotecnología Genómica-Instituto Politécnico Nacional, Colonia Narciso Mendoza, Reynosa, Tamaulipas, México.
authors.forename: P
authors.initials: P
authors.lastname: Ambriz-Morales
authors.affiliation: Centro de Biotecnología Genómica-Instituto Politécnico Nacional, Colonia Narciso Mendoza, Reynosa, Tamaulipas, México.
authors.forename: G M
authors.initials: GM
authors.lastname: Parra-Bracamonte
mesh_terms: D000483:Alleles; D000818:Animals; D001522:Behavior, Animal; D001947:Breeding; D002417:Cattle; D005260:Female; D005787:Gene Frequency; D005838:Genotype; D008297:Male; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D025341:Principal Component Analysis; D020033:Protein Isoforms / Q000235:genetics; D019655:Quantitative Trait, Heritable; D011954:Receptors, Dopamine / Q000235:genetics*; D013694:Temperament
chemical_list: D020033:Protein Isoforms; D011954:Receptors, Dopamine