title: [Related factors analysis of spontaneous cerebrospinal fluid leak recurrence after endoscope operation].
abstract: OBJECTIVE
  To Summarize and analyze the clinical characteristics and treatment of patients with spontaneous cerebrospinal fluid rhinorrhea, and to explore the related factors of recurrence.
  
  
  METHODS
  Retrospective- ly analyze the clinical data of 58 patients of spontaneous cerebrospinal fluid rhinorrhea from July 2002 to July 2012, combined with its clinical characteristics, and statistically analyze the related recurrence factors.
  
  
  RESULTS
  Fifty-eight cases were accepted the nasal endoscopic repairment of cerebrospinal fluid rhinorrheak, follow-up 3 years, 20 cases (34.5%) recurred, 1 case recurred in half a year after operation. In the first year, there were 10 cases recurred. In the second year there were 9 cases recurred, and 1 case recurred in the third year. Through multiariable analysis it was found that higher BMI, empty sella and skull base bone defect were the independent risk factors influencing the recurrence of spontaneous cerebrospinal fluid rhinorrhea (P < 0.05).
  
  
  CONCLUSIONS
  The recurrence rate of spontaneous cerebrospinal fluid rhinorrhea is high, needing long-term follow-up. Higher BMI, empty sella, skull base bone defect are independent risk factors of recurrence of the disease, and the treatment should be individualized.
authors.forename: Huanxin
authors.initials: H
authors.lastname: Yu
authors.forename: Haiyan
authors.initials: H
authors.lastname: Li
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
mesh_terms: D002559:Cerebrospinal Fluid Rhinorrhea / Q000473:pathology* / Q000601:surgery*; D004652:Empty Sella Syndrome / Q000473:pathology; D004724:Endoscopy / Q000009:adverse effects*; D006801:Humans; D009666:Nose; D012008:Recurrence; D012189:Retrospective Studies; D012307:Risk Factors; D019291:Skull Base / Q000473:pathology