title: Outcome of everolimus eluting bioabsorbable vascular scaffold (BVS) compared to non BVS drug eluting stent in the management of ST-segment elevation myocardial infarction (STEMI) - A comparative study.
abstract: BACKGROUND
  The safety and efficacy of everolimus eluting bioabsorbable vascular scaffold (BVS) in the management of "ST" segment elevation myocardial infarction (STEMI) are yet to be established.
  
  
  OBJECTIVE
  To evaluate immediate and short term safety and efficacy of the everolimus-eluting ABSORB BVS compared with non BVS drug eluting stent (DES) in patients with STEMI.
  
  
  METHODS
  From December 2013 to December 2014, 220 patients with STEMI were included in this study. Among them, 35 patients treated with BVS were compared with a control group composed of 180 patients who underwent non BVS DES implantation in the same time period. The incidence of major adverse cardiac events (MACE: stent thrombosis: death, non-fatal myocardial infarction, or target vessel/lesion revascularization) before discharge and up to six months was evaluated.
  
  
  RESULTS
  1 vessel disease was more frequent whereas, 2 and 3 vessel disease was less frequent in BVS group. Procedural characteristics were also similar between groups, except for the use of post dilation (p=0.04). Procedural success, in-hospital, and up to six-month MACE rates were similar between both groups. Definite or probable stent thrombosis did not occur (according to the ARC criteria) in BVS patients, though two patients during the index admission and another two patients in the first month after DES implantation had stent thrombosis.
  
  
  CONCLUSIONS
  The use of the ABSORB BVS for STEMI is feasible and associated with good procedural safety, and angiographic success rate.
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Rabin
authors.initials: R
authors.lastname: Chakraborty
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India. Electronic address: dr_soumyapatra@rediffmail.com.
authors.forename: Soumya
authors.initials: S
authors.lastname: Patra
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Suvro
authors.initials: S
authors.lastname: Banerjee
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Arindam
authors.initials: A
authors.lastname: Pande
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Aftab
authors.initials: A
authors.lastname: Khan
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Prakash Chandra
authors.initials: PC
authors.lastname: Mandol
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Debashish
authors.initials: D
authors.lastname: Ghosh
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Swapan Kumar
authors.initials: SK
authors.lastname: De
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Sankha Subhro
authors.initials: SS
authors.lastname: Das
authors.affiliation: Department of Cardiology, Apollo Gleneagles Hospitals, Kolkata, West Bengal, India.
authors.forename: Raja
authors.initials: R
authors.lastname: Nag
mesh_terms: D020341:Absorbable Implants; D000328:Adult; D000368:Aged; D002317:Cardiovascular Agents / Q000008:administration & dosage*; D020099:Coated Materials, Biocompatible; D017023:Coronary Angiography; D023903:Coronary Restenosis / Q000209:etiology; D003328:Coronary Thrombosis / Q000209:etiology; D054855:Drug-Eluting Stents; D000068338:Everolimus / Q000008:administration & dosage*; D005240:Feasibility Studies; D006801:Humans; D007194:India; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000295:instrumentation* / Q000401:mortality; D011446:Prospective Studies; D011474:Prosthesis Design; D012008:Recurrence; D012307:Risk Factors; D000072657:ST Elevation Myocardial Infarction / Q000000981:diagnostic imaging / Q000401:mortality / Q000628:therapy*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D002317:Cardiovascular Agents; D020099:Coated Materials, Biocompatible; D000068338:Everolimus
keywords: Bioabsorbable vascular scaffold; Drug eluting stent; Everolimus eluting; ST-segment elevation myocardial infarction