title: Pulmonary hypertension.
abstract: In 2015, more than 800 papers were published in the field of pulmonary hypertension. A Clinical Year in Review article cannot possibly incorporate all this work and needs to be selective. The recently published European guidelines for the diagnosis and treatment of pulmonary hypertension contain an inclusive summary of all published clinical studies conducted until very recently. Here, we provide an overview of papers published after the finalisation of the guideline. In addition, we summarise recent advances in pulmonary vasculature science. The selection we made from the enormous amount of published work undoubtedly reflects our personal views and may not include all papers with a significant impact in the near or more distant future. The focus of this paper is on the diagnosis of pulmonary arterial hypertension, understanding the success of combination therapy on the right ventricle and scientific breakthroughs.
authors.affiliation: Dept of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands A.vonk@vumc.nl.
authors.forename: Anton
authors.initials: A
authors.lastname: Vonk Noordegraaf
authors.affiliation: Dept of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: Joanne A
authors.initials: JA
authors.lastname: Groeneveldt
authors.affiliation: Dept of Pulmonary Medicine, VU University Medical Center, Amsterdam, The Netherlands.
authors.forename: Harm Jan
authors.initials: HJ
authors.lastname: Bogaard
mesh_terms: D000818:Animals; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy; D012307:Risk Factors; D016896:Treatment Outcome