title: Solitary intraosseous myofibroma of the tibia in an adult patient: A case report.
abstract: Myofibromas are mesenchymal tumors showing myofibroblastic differentiation and found most frequently in the head and neck region. While several cases of myofibromas have been reported in adults, they have not been described in long bones of the appendicular skeleton. We describe an otherwise healthy young woman who presented with a progressive incapacitating pain in her right shin. Imaging studies revealed a well-circumscribed osteolytic lesion with slight marginal sclerosis confined to the proximal tibia metaphysis, without a soft tissue component. Surgical intervention was performed and histological examination identified a myofibroma. This case represents an extremely rare occurrence of an intraosseous myofibroma involving a long bone in an adult patient. Although solitary myofibroma is a rare lesion in the skeletal bones of adults we believe it should be included in the differential diagnosis of a solitary lytic mass in bone, especially if it is associated with pain.
authors.affiliation: Departments of Orthopedics, Rabin Medical Center, Petach Tikva 49100 and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Shemesh
authors.affiliation: Departments of Orthopedics, Rabin Medical Center, Petach Tikva 49100 and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: Y
authors.initials: Y
authors.lastname: Kosashvili
authors.affiliation: Departments of Orthopedics, Rabin Medical Center, Petach Tikva 49100 and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: E
authors.initials: E
authors.lastname: Sidon
authors.affiliation: Departments of Pathology, Rabin Medical Center, Petach Tikva 49100 and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Fichman
authors.affiliation: Departments of Orthopedics, Rabin Medical Center, Petach Tikva 49100 and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: N
authors.initials: N
authors.lastname: Cohen
authors.affiliation: Departments of Orthopedics, Rabin Medical Center, Petach Tikva 49100 and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
authors.forename: S
authors.initials: S
authors.lastname: Velkes
keywords: Adult; Intraosseous; Myofibroma; Tibia