title: MPR-CT Imaging for Stapes Prosthesis: Accuracy and Clinical Significance.
abstract: OBJECTIVE
  The aims of this article are: 1) to re-evaluate the accuracy of multiple planar reconstruction computed tomography (MPR-CT) imaging on stapes-prosthesis parameters, and 2) to clarify possible relationships between prosthesis intravestibular depth and postoperative hearing outcomes.
  
  
  METHODS
  Seventy patients (46 women and 24 men; 32 right and 38 left sides) with the mean age of 40 years (range, 19-62 yr) with clinical otosclerosis.
  
  
  METHODS
  All patients underwent stapedotomy and were implanted with the same type of titanium piston prosthesis by the same surgeon.
  
  
  METHODS
  Postoperative MPR-CTs were obtained at patients' follow-up visits. The length and intravestibular depth of the stapes prosthesis (including absolute and relative depth) were calculated from the MPR-CT imaging. Relationships between the intravestibular depth of the prosthesis and hearing outcomes (pre- and postoperative audiograms) were analyzed using Spearman correlation analyses.
  
  
  RESULTS
  The length of the prosthesis was overestimated by 1.8% (0.1 mm) by the MPR-CT imaging. Axial and coronal measurements were significantly correlated (p < 0.05). There was great intersubject variability in hearing outcomes differed insignificantly, regardless of intravestibular depth within the security range. No relationships were found between the intravestibular depth of the stapes prosthesis, as measured with MPR-CT, and postoperative hearing results.
  
  
  CONCLUSIONS
  MPR-CT can provide an accurate estimation of stapes prosthesis parameters. However, the prosthesis intravestibular depth did not seem to affect postoperative hearing outcomes.
authors.affiliation: *Department of Otology and Skull Base Surgery, Key Laboratory of Hearing Medicine, Ministry of Health, Eye Ear Nose and Throat Hospital of Fudan University, Shanghai, China †Department of Head and Neck Surgery, David Geffen School of Medicine, University of California, Los Angeles, California, U.S.A. ‡Department of Ear Nose and Throat, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu §Department of Radiology, Eye Ear Nose and Throat, Hospital of Fudan University, Shanghai, China.
authors.forename: Yanqing
authors.initials: Y
authors.lastname: Fang
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
authors.forename: John J
authors.initials: JJ
authors.lastname: Galvin
authors.forename: Duoduo
authors.initials: D
authors.lastname: Tao
authors.forename: Rui
authors.initials: R
authors.lastname: Deng
authors.forename: Xiong
authors.initials: X
authors.lastname: Ou
authors.forename: Yangwenyi
authors.initials: Y
authors.lastname: Liu
authors.forename: Peidong
authors.initials: P
authors.lastname: Dai
authors.forename: Yan
authors.initials: Y
authors.lastname: Sha
authors.forename: Tianyu
authors.initials: T
authors.lastname: Zhang
authors.forename: Bing
authors.initials: B
authors.lastname: Chen
mesh_terms: D000328:Adult; D005260:Female; D006309:Hearing; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009998:Ossicular Prosthesis; D010040:Otosclerosis / Q000000981:diagnostic imaging / Q000601:surgery; D011184:Postoperative Period; D013199:Stapes / Q000000981:diagnostic imaging*; D013201:Stapes Surgery; D014057:Tomography, X-Ray Computed / Q000379:methods*; D016896:Treatment Outcome; D055815:Young Adult