title: Immune mediated crescentic MPGN secondary to HBV infection: A rare presentation for a common infection.
abstract: Hepatitis B virus (HBV) infection presenting as crescentic glomerulonephritis in the absence of cryoglobulinemia is an extremely rare phenomenon. We report a case of a 44-year-old male with HBV infection, who underwent kidney biopsy for rapidly progressive renal failure and nephrotic range proteinuria. Histopathological evaluation of the kidney biopsy was consistent with immune complex mediated crescentic membranoproliferative glomerulonephritis (MPGN). The patient achieved complete renal and virological remission with steroids, plasmapheresis and antiviral therapy. This case report summarises the importance of early initiation of immunosuppression and plasmapheresis under antiviral coverage for improved clinical outcomes.
authors.affiliation: Department of Nephrology, Kasturba Medical College, Manipal University, Mangalore, India.
authors.forename: Aswani Srinivas
authors.initials: AS
authors.lastname: Mareddy
authors.affiliation: Department of Nephrology, Kasturba Medical College, Manipal University, Mangalore, India.
authors.forename: Dharshan
authors.initials: D
authors.lastname: Rangaswamy
authors.affiliation: Department of Pathology and Lab Medicine, Manipal Hospitals, Bengaluru, India.
authors.forename: Mahesha
authors.initials: M
authors.lastname: Vankalakunti
authors.affiliation: Department of Nephrology, Kasturba Medical College, Manipal University, Mangalore, India.
authors.forename: Ravindra Prabhu
authors.initials: RP
authors.lastname: Attur
authors.affiliation: Department of Nephrology, Kasturba Medical College, Manipal University, Mangalore, India.
authors.forename: Shankar Prasad
authors.initials: SP
authors.lastname: Nagaraju
authors.affiliation: Department of Medicine, Kasturba Medical College, Manipal University, Mangalore, India.
authors.forename: Neeraja
authors.initials: N
authors.lastname: Koti
keywords: Hepatitis B Virus; MPGN; crescentic glomerulonephritis; crescentic membranoproliferative glomerulonephritis