title: Molecular epidemiology of noroviruses associated with sporadic gastroenteritis in Guangzhou, China, 2013-2015.
abstract: Norovirus diarrhea is a great threat to public health worldwide. To characterize the prevalence of circulating noroviruses associated with sporadic gastroenteritis cases in Guangzhou, 215 stool specimens were collected during two consecutive cold seasons in 2013-2015. Noroviruses were detected in 25 (11.63 %) samples, and GII.4 (6/9) and GII.17 (10/16) were identified as the most predominant variants of each of those seasons. The remaining strains belonged to the genotypes GII.P12/GII.3, GII.2, and GI.Pb/GI.6. The phylogenetic relationships of the GII.17 strains were analyzed based on their capsid protein sequences. This study suggests a significant shift of predominant variants associated with sporadic gastroenteritis in Guangzhou.
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, No. 100, Xianlie Zhong Road, Guangzhou, 510070, People's Republic of China.|Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, 510070, People's Republic of China.
authors.forename: Liang
authors.initials: L
authors.lastname: Xue
authors.affiliation: Department of Cardiology, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, People's Republic of China.
authors.forename: Ruimin
authors.initials: R
authors.lastname: Dong
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, No. 100, Xianlie Zhong Road, Guangzhou, 510070, People's Republic of China. wuqp203@163.com.|Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, 510070, People's Republic of China. wuqp203@163.com.
authors.forename: Qingping
authors.initials: Q
authors.lastname: Wu
authors.affiliation: Laboratory Department, The Third Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510630, People's Republic of China.
authors.forename: Yonglai
authors.initials: Y
authors.lastname: Li
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, No. 100, Xianlie Zhong Road, Guangzhou, 510070, People's Republic of China.|Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, 510070, People's Republic of China.
authors.forename: Weicheng
authors.initials: W
authors.lastname: Cai
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, No. 100, Xianlie Zhong Road, Guangzhou, 510070, People's Republic of China.|Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, 510070, People's Republic of China.
authors.forename: Xiaoxia
authors.initials: X
authors.lastname: Kou
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, No. 100, Xianlie Zhong Road, Guangzhou, 510070, People's Republic of China.|Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, 510070, People's Republic of China.
authors.forename: Jumei
authors.initials: J
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Institute of Microbiology, No. 100, Xianlie Zhong Road, Guangzhou, 510070, People's Republic of China.|Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Open Laboratory of Applied Microbiology, Guangzhou, 510070, People's Republic of China.
authors.forename: Weipeng
authors.initials: W
authors.lastname: Guo
mesh_terms: D000328:Adult; D001483:Base Sequence; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D036022:Capsid Proteins / Q000235:genetics; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D005838:Genotype; D006801:Humans; D007223:Infant; D008875:Middle Aged; D017720:Molecular Epidemiology; D008969:Molecular Sequence Data; D029322:Norovirus / Q000235:genetics*; D010802:Phylogeny; D055815:Young Adult
chemical_list: D036022:Capsid Proteins