title: Association between Serum Polybrominated Diphenyl Ether Levels and Residential Proximity to Solid-Waste Facilities.
abstract: As consumer products treated with polybrominated diphenyl ethers (PBDEs) reach the end of their life cycle, they often are discarded into solid-waste facilities, offering a potential reservoir for exposure. The likelihood of exposures to PBDEs by residents living near those sites rarely has been explored. This study collected blood samples from 923 female participants in the California Teachers Study in 2011-2013 and examined the association between participants' residential proximity to solid-waste facilities with potential release of PBDEs and serum levels of three congeners (BDE-47, BDE-100, and BDE-153). General linear regression analysis was used to examine the association, adjusting for age, race, body-mass index, neighborhood socioeconomic status, and urban residency. Compared to participants living >10 km from any selected site, those living within 2 km had 45% higher BDE-47 (95% CI: 5-100%) and BDE-100 (95% CI: 0-109%) levels, and those living between 2 and 10 km had 35% higher BDE-47 (95% CI: 0-82%) and 29% higher BDE-100 (95% CI: -9 to 82%) levels. No associations were found for BDE-153. Living close to some solid waste sites may be related to higher serum BDE-47 and BDE-100 levels. Studies with comprehensive exposure assessments are needed to confirm these initial observations.
authors.affiliation: Cancer Prevention Institute of California , Berkeley, California 94704, United States.
authors.forename: Ruiling
authors.initials: R
authors.lastname: Liu
authors.affiliation: Cancer Prevention Institute of California , Berkeley, California 94704, United States.
authors.forename: David O
authors.initials: DO
authors.lastname: Nelson
authors.affiliation: Cancer Prevention Institute of California , Berkeley, California 94704, United States.
authors.forename: Susan
authors.initials: S
authors.lastname: Hurley
authors.affiliation: Department of Toxic Substances Control, California Environmental Protection Agency , Berkeley, California 95812, United States.
authors.forename: Myrto
authors.initials: M
authors.lastname: Petreas
authors.affiliation: Department of Toxic Substances Control, California Environmental Protection Agency , Berkeley, California 95812, United States.
authors.forename: June-Soo
authors.initials: JS
authors.lastname: Park
authors.affiliation: Department of Toxic Substances Control, California Environmental Protection Agency , Berkeley, California 95812, United States.
authors.forename: Yunzhu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Toxic Substances Control, California Environmental Protection Agency , Berkeley, California 95812, United States.
authors.forename: Weihong
authors.initials: W
authors.lastname: Guo
authors.affiliation: Department of Population Sciences, Beckman Research Institute of the City of Hope , Duarte, California 91010, United States.
authors.forename: Leslie
authors.initials: L
authors.lastname: Bernstein
authors.affiliation: Cancer Prevention Institute of California , Berkeley, California 94704, United States.
authors.forename: Andrew
authors.initials: A
authors.lastname: Hertz
authors.affiliation: Cancer Prevention Institute of California , Berkeley, California 94704, United States.|Department of Health Research and Policy, Stanford University School of Medicine , Stanford, California 94305, United States.
authors.forename: Peggy
authors.initials: P
authors.lastname: Reynolds
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002140:California; D004784:Environmental Monitoring; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000097:blood*; D006801:Humans; D008055:Lipids / Q000737:chemistry; D008875:Middle Aged; D011075:Polybrominated Biphenyls / Q000097:blood; D012111:Residence Characteristics; D062611:Solid Waste
chemical_list: D055768:Halogenated Diphenyl Ethers; D008055:Lipids; D011075:Polybrominated Biphenyls; D062611:Solid Waste; C517828:hexabrominated diphenyl ether 153; C517827:pentabrominated diphenyl ether 100; C511295:2,2',4,4'-tetrabromodiphenyl ether