title: Seroprevalence of Helicobacter pylori Infection in Renal Transplant Recipient Attending Duhok Kidney Disease Center.
abstract: BACKGROUND
  Helicobacter pylori plays an important role in the development of gastritis, peptic ulcer disease, and gastric cancer in the general population. Although dyspeptic complaints are frequent in renal transplant subjects, the role of H pylori in such complaints is not clear. This study was conducted to examine the prevalence of H pylori infection in patients with renal transplant and its role in the development of upper gastrointestinal tract (GIT) symptoms.
  
  
  METHODS
  We compared the prevalence of H pylori in 109 renal transplant subjects with the prevalence of 161 healthy volunteers using an enzyme-linked immunosorbent assay to measure anti-H pylori IgG. Then, within the transplant group, we stratified our data in accordance with different variables, including upper GIT symptoms, sex, education level, smoking, and dialysis history.
  
  
  RESULTS
  The prevalence of H pylori in the control group was 111 of 161 (68.9%), which was significantly higher than that found in renal transplant subjects (48/109; 43.04%; P = .001). Within the transplant group, no association was found between immunoglobulin G positivity and different variables including upper GIT symptoms, sex, education level, smoking, and dialysis history.
  
  
  CONCLUSIONS
  The prevalence of H pylori was lower in transplant subjects than that of general population. Upper GIT symptoms were equally found in both groups. Hence, the routine eradication of H pylori might not be indicated.
authors.affiliation: Department of Internal Medicine, College of Medicine, University of Duhok, Duhok, Iraq. Electronic address: nawfal.hussein@yahoo.com.
authors.forename: N R
authors.initials: NR
authors.lastname: Hussein
authors.affiliation: Department of Internal Medicine, College of Medicine, University of Duhok, Duhok, Iraq.
authors.forename: Z S M
authors.initials: ZS
authors.lastname: Saleem
authors.affiliation: Department of Hematology, College of Pharmacy, University of Duhok, Duhok, Iraq.
authors.forename: A A
authors.initials: AA
authors.lastname: Balatay
authors.affiliation: Duhok Kidney Disease Center, Duhok, Iraq.
authors.forename: K H
authors.initials: KH
authors.lastname: Abd
authors.affiliation: Infection Control Department, DOH, Duhok, Iraq.
authors.forename: S
authors.initials: S
authors.lastname: Daniel
authors.affiliation: Infection Control Department, DOH, Duhok, Iraq.
authors.forename: A A
authors.initials: AA
authors.lastname: Taha
authors.affiliation: Department of Surgery, College of Medicine, University of Duhok, Duhok, Iraq.
authors.forename: N M R
authors.initials: NM
authors.lastname: Ibrahim
authors.affiliation: Department of Biology, Faculty of Sciences, University of Zakho, Zakho, Iraq.
authors.forename: M S
authors.initials: MS
authors.lastname: Assafi
mesh_terms: D000328:Adult; D000368:Aged; D000888:Antibodies, Anti-Idiotypic / Q000097:blood; D016022:Case-Control Studies; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D016481:Helicobacter Infections / Q000097:blood / Q000453:epidemiology*; D016480:Helicobacter pylori / Q000276:immunology; D006801:Humans; D007493:Iraq / Q000453:epidemiology; D007674:Kidney Diseases / Q000097:blood / Q000382:microbiology* / Q000601:surgery; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D015995:Prevalence; D016036:Seroepidemiologic Studies
chemical_list: D000888:Antibodies, Anti-Idiotypic; C048844:anti-IgG