title: Follicular fluid total antioxidant capacity levels in PCOS.
abstract: In this study, our aim was to assess total antioxidant capacity (TAC) levels in follicular fluid (FF) and their relationship to clinical pregnancy rates in PCOS patients undergoing assisted reproduction (ART). Twenty-two women with polycystic ovary syndrome (PCOS) (Group 1) and 41 women without PCOS (Group 2) were included in this study. Clinical and laboratory parameters and FF TAC levels were investigated. No statistically significant differences were found between the groups with regard to age and baseline parameters. Although we could not demonstrate a significant difference in FF TAC levels between the two groups (p=0.469), there was a significant positive correlation between FF TAC and clinical pregnancy rates, BMI, and the duration of infertility for the entire group (r=0.254, p=0.048; r=0.312, p=0.013; r=0.259, p=0.040; respectively). Owing to the correlation between FF TAC and the clinical pregnancy rates, further studies evaluating the impact of FF TAC levels on ART outcomes in patients with PCOS and other etiologies of infertility are needed.
authors.affiliation: a Dr. Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey .
authors.forename: Nafiye
authors.initials: N
authors.lastname: Yilmaz
authors.affiliation: b Konya Education and Research Hospital , Konya , Turkey , and.
authors.forename: Hasan Ali
authors.initials: HA
authors.lastname: Inal
authors.affiliation: c Department of IVF Unit, Faculty of Medicine, Hitit University , Corum , Turkey.
authors.forename: Umit
authors.initials: U
authors.lastname: Gorkem
authors.affiliation: a Dr. Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey .
authors.forename: Ayla
authors.initials: A
authors.lastname: Sargin Oruc
authors.affiliation: a Dr. Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey .
authors.forename: Saynur
authors.initials: S
authors.lastname: Yilmaz
authors.affiliation: a Dr. Zekai Tahir Burak Women's Health Education and Research Hospital , Ankara , Turkey .
authors.forename: Ayten
authors.initials: A
authors.lastname: Turkkani
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000032:analysis*; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D005260:Female; D015571:Follicular Fluid / Q000737:chemistry*; D006801:Humans; D007247:Infertility, Female / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D011085:Polycystic Ovary Syndrome / Q000150:complications / Q000503:physiopathology*; D011247:Pregnancy; D018873:Pregnancy Rate; D011446:Prospective Studies; D027724:Reproductive Techniques, Assisted / Q000706:statistics & numerical data*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants
keywords: Total antioxidant capacity; assisted reproductive technology (ART) outcomes; follicular fluid; polycystic ovary syndrome (PCOS)