title: [Sperm DNA fragmentation index and the success rate of IVF/ICSI].
abstract: Sperm DNA fragmentation index (DFI) refers to the percentage of DNA strand breaks in the total sperm. Many studies suggest that elevated DFI can lead to male infertility and early spontaneous abortion. High-DFI patients are more likely to fail in assisted reproduction and preliminary treatment or prevention methods have been developed for this population. This review focuses on the impact of DFI on clinical pregnancy outcomes and progress in the studies of its treatment.
authors.forename: Di
authors.initials: D
authors.lastname: Xi
authors.forename: Yun
authors.initials: Y
authors.lastname: Chen
authors.forename: Yu-tian
authors.initials: YT
authors.lastname: Dai
mesh_terms: D000022:Abortion, Spontaneous; D002843:Chromatin; D053938:DNA Fragmentation; D005260:Female; D006801:Humans; D007248:Infertility, Male; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D020554:Sperm Injections, Intracytoplasmic; D013094:Spermatozoa
chemical_list: D002843:Chromatin