title: [Experimental study on preventive effect of Yougui drink on femoral head necrosis in rats under micro CT].
abstract: OBJECTIVE
  To explore the preventive effect of Yougui drink on femoral head necrosis in rats under micro CT.
  
  
  METHODS
  Twenty-five SD rats were divided into steroid hormone group (group A, 10 rats ), Yougui drink group (group B,10 rats) and normal group (group C,5 rats)with random number table. Endotoxin were injected into abdominal cavity of rats in group A and B for 2 days, methylprednisolone sodium succinate were injected by gluteus for twice a week continued for 6 weeks; group B were gavaged by Yougui drink (veryday for 8 weeks; group C did not do any processing. All rats were killed on the 10th weeks,m icro CT were used to scan femoral head in vitro and preventive effect of Yougui drink (n femoral head necrosis in rats.
  
  
  RESULTS
  There was statistical significance in BMD, BV/TV, Tb.N, Tb, Th, Thb, Sp, BS/TV and DA but no significance in SMI between group A and B. Comparison between A and C, there was significant meaning in BMD, BV/TV, Tb.N, Tb, Th, Tb, Sp, BS/TV, DA and SMI.
  
  
  CONCLUSIONS
  Yougui drink on femoral head necrosis in rats under micro CT has preventive effect from BMD BV/TV, Tb.N, Tb, Th, Tb, Sp, BS/TV and DA.
authors.forename: Xing-chao
authors.initials: XC
authors.lastname: Shen
authors.forename: Cai-yuan
authors.initials: CY
authors.lastname: Song
authors.forename: Shuai-jie
authors.initials: SJ
authors.lastname: Lyu
authors.forename: Hang-xing
authors.initials: HX
authors.lastname: Bao
authors.forename: Pei-jian
authors.initials: PJ
authors.lastname: Tong
authors.forename: Lu-wei
authors.initials: LW
authors.lastname: Xiao
mesh_terms: D000818:Animals; D017209:Apoptosis; D015519:Bone Density; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D005271:Femur Head Necrosis / Q000000981:diagnostic imaging / Q000473:pathology / Q000517:prevention & control*; D051381:Rats; D017207:Rats, Sprague-Dawley; D055114:X-Ray Microtomography / Q000379:methods*
chemical_list: D004365:Drugs, Chinese Herbal; C552041:yougui