title: Do Not Forget the Glycophorin A: An Unusual Case of Myeloid Sarcoma.
abstract: Acute erythroid leukemia is rare, with isolated reports on presentation as an extramedullary tumor mass (myeloid sarcoma). We describe a case of pure erythroid leukemia presenting as an orbital mass in a 1-year, 9-month-old girl. This is only the second case described in a child. Tissue biopsy of the tumor mass showed medium-sized cells that were glycophorin A positive and negative with conventional myeloid markers. Flow cytometry, bone marrow aspirate, and trephine confirmed the diagnosis of pure erythroid leukemia.
authors.affiliation: Departments of *Anatomical Pathology ∥Molecular Medicine and Hematology #Pediatrics, Division of Pediatric Oncology †National Health Laboratory Services ‡Chris Hani Baragwanath Academic Hospital §Faculty of Health Sciences, University of the Witwatersrand ¶Charlotte Maxeke Academic Hospital, Soweto, Johannesburg, South Africa.
authors.forename: Reena D
authors.initials: RD
authors.lastname: Mohanlal
authors.forename: Jenifer
authors.initials: J
authors.lastname: Vaughan
authors.forename: Narisha
authors.initials: N
authors.lastname: Ramparsad
authors.forename: Gita
authors.initials: G
authors.lastname: Naidu
mesh_terms: D001856:Bone Marrow Examination / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D005434:Flow Cytometry; D006021:Glycophorins / Q000032:analysis*; D006801:Humans; D007223:Infant; D004915:Leukemia, Erythroblastic, Acute / Q000175:diagnosis*; D009915:Orbit / Q000473:pathology; D023981:Sarcoma, Myeloid / Q000175:diagnosis*; D014207:Trephining
chemical_list: D006021:Glycophorins