title: First detection of Mycobacterium triplex in Latin America.
abstract: In this study we describe the first isolation of Mycobacterium triplex in Latin America. This species causes infections in humans, with very few reports from around the world. We isolated two sputum specimens of a patient with a 6-year history of human immunodeficiency and tuberculosis treatment failure. All tests used confirmed M. triplex and the patient responded well to drug therapy for 18months.
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: Carlos Eduardo Dias
authors.initials: CE
authors.lastname: Campos
authors.affiliation: Hospital Sanatório Partenon, Secretaria Estadual da Saude, Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Cláudia Fontoura
authors.initials: CF
authors.lastname: Dias
authors.affiliation: Hospital Sanatório Partenon, Secretaria Estadual da Saude, Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Gisela
authors.initials: G
authors.lastname: Unis
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: Paulo Cesar
authors.initials: PC
authors.lastname: de Souza Caldas
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: Paulo
authors.initials: P
authors.lastname: Redner
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: Luciana Distásio
authors.initials: LD
authors.lastname: de Carvalho
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: Ana Paula Chaves Sobral
authors.initials: AP
authors.lastname: Gomes
authors.affiliation: Fundação Estadual de Produção e Pesquisa em Saúde, Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: Marta Osório
authors.initials: MO
authors.lastname: Ribeiro
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil.
authors.forename: Fátima Cristina Onofre Fandinho
authors.initials: FC
authors.lastname: Montes
authors.affiliation: Emerging Bacterial Pathogens Unit, San Raffaele Scientific Institute, Milan, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Tortoli
authors.affiliation: National Reference Laboratory for Tuberculosis, Centro de Referência Professor Hélio Fraga, Escola Nacional de Saúde Pública, Fiocruz, Rio de Janeiro, Brazil. Electronic address: jepramos@ensp.fiocruz.br.
authors.forename: Jesus Pais
authors.initials: JP
authors.lastname: Ramos
mesh_terms: D060085:Coinfection; D004269:DNA, Bacterial; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000188:drug therapy; D006801:Humans; D007843:Latin America / Q000453:epidemiology; D008875:Middle Aged; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications / Q000453:epidemiology / Q000382:microbiology*; D009170:Nontuberculous Mycobacteria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D017422:Sequence Analysis, DNA; D013183:Sputum / Q000382:microbiology*
chemical_list: D004269:DNA, Bacterial
keywords: M. triplex; Nontuberculous mycobacteria; Pulmonary disease; Sequencing