title: Brønsted Acid-Mediated Hydrative Arylation of Unactivated Alkynes.
abstract: The Brønsted acid-mediated reaction of unactivated alkynes with aryl sulfoxides leads to simultaneous hydration and intermolecular C-C bond formation. This solvent- and metal-free transformation directly delivers α-arylated carbonyl compounds as the products of a formal hydrative arylation in an atom-economical manner. The products bear useful synthetic handles for further functionalization.
authors.affiliation: Faculty of Chemistry, Institute of Organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria.
authors.forename: Daniel
authors.initials: D
authors.lastname: Kaiser
authors.affiliation: Centro de Química Estrutural, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisboa, Portugal.
authors.forename: Luís F
authors.initials: LF
authors.lastname: Veiros
authors.affiliation: Faculty of Chemistry, Institute of Organic Chemistry, University of Vienna, Währinger Strasse 38, 1090, Vienna, Austria. nuno.maulide@univie.ac.at.
authors.forename: Nuno
authors.initials: N
authors.lastname: Maulide
keywords: alkynes; arylation; organic chemistry; rearrangement; sulfoxides