title: Coronally advanced flap with or without porcine collagen matrix for root coverage: a randomized clinical trial.
abstract: OBJECTIVE
  The objective of this study is to clinically evaluate the outcomes following treatment of single gingival recessions with either coronally advanced flap technique (CAF) alone or combined with a porcine collagen matrix graft (CM).
  
  
  METHODS
  This is a randomized parallel design clinical trial, including forty patients with single Miller Class I or II gingival recession, with a depth ≥ 2 mm and located at upper canines or premolars. The patients were randomly assigned to receive either CAF or CAF + CM. The primary outcome variable was gingival recession reduction (Rec Red).
  
  
  RESULTS
  Baseline recession depth was 3.14 ± 0.51 mm for CAF group and 3.16 ± 0.65 mm for CAF + CM group (p > 0.05). Both groups showed significant Rec Red (p < 0.05), up to 6 months. Rec Red for CAF + CM was 2.41 ± 0.73 mm and was 2.25 ± 0.50 mm for CAF alone (p > 0.05). Root coverage was 77.2 % in the CAF + CM group and 72.1 % in the CAF group (p > 0.05). Complete root coverage (CRC) was found in 40 % of the cases in the CAF + CM group and in 35 % of the sites treated with CAF. Keratinized tissue thickness (KTT) was 0.26 mm higher in CAF + CM group (p < 0.05).
  
  
  CONCLUSIONS
  It can be concluded that CAF + CM does not provide a superior recession reduction when compared to CAF; however, it may offer a small gain in KTT after 6 months.
  
  
  CONCLUSIONS
  CAF + CM can be suggested as a valid therapeutic option to achieve root coverage and some increase in soft tissue thickness after 6 months.
authors.affiliation: Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, State University of Campinas - UNICAMP, Av. Limeira, 901, Areião, Piracicaba, São Paulo, Brazil.
authors.forename: Ana Regina Oliveira
authors.initials: ARO
authors.lastname: Moreira
authors.affiliation: Department of Periodontology, São José dos Campos Dental School, State University of São Paulo, São José dos Campos, São Paulo, Brazil.
authors.forename: Mauro Pedrine
authors.initials: MP
authors.lastname: Santamaria
authors.affiliation: Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, State University of Campinas - UNICAMP, Av. Limeira, 901, Areião, Piracicaba, São Paulo, Brazil.
authors.forename: Karina Gonzales
authors.initials: KG
authors.lastname: Silvério
authors.affiliation: Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, State University of Campinas - UNICAMP, Av. Limeira, 901, Areião, Piracicaba, São Paulo, Brazil.
authors.forename: Marcio Zaffalon
authors.initials: MZ
authors.lastname: Casati
authors.affiliation: Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, State University of Campinas - UNICAMP, Av. Limeira, 901, Areião, Piracicaba, São Paulo, Brazil.
authors.forename: Francisco Humberto
authors.initials: FH
authors.lastname: Nociti Junior
authors.affiliation: Department of Periodontology, University of Bern, Bern, Switzerland.
authors.forename: Anton
authors.initials: A
authors.lastname: Sculean
authors.affiliation: Department of Prosthodontics and Periodontics, Division of Periodontics, Piracicaba Dental School, State University of Campinas - UNICAMP, Av. Limeira, 901, Areião, Piracicaba, São Paulo, Brazil. enilson@unicamp.br.
authors.forename: Enilson Antonio
authors.initials: EA
authors.lastname: Sallum
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D003094:Collagen / Q000627:therapeutic use*; D003238:Connective Tissue / Q000637:transplantation*; D005260:Female; D005889:Gingival Recession / Q000601:surgery*; D006801:Humans; D008297:Male; D016037:Single-Blind Method; D013524:Surgical Flaps; D013552:Swine; D016896:Treatment Outcome
chemical_list: D001672:Biocompatible Materials; D003094:Collagen
keywords: Collagen/therapeutic use; Gingival recession/surgery; Root coverage; Treatment outcome