title: Enantioselective total synthesis and structural reassignment of (+)-alsmaphorazine E via a traceless chirality transfer strategy.
abstract: The first enantioselective total synthesis of (+)-alsmaphorazine E has been achieved through a traceless chirality transfer strategy, which also enabled structural reassignment of the natural product. Key features of this efficient approach entail a catalytic intramolecular oxidative cyclization, a diastereoselective oxidative cyclic aminal formation and a radical cyclization/transannular aza-Michael addition cascade.
authors.affiliation: Department of Chemistry, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, P. R. China. hfding@zju.edu.cn.
authors.forename: Kuan
authors.initials: K
authors.lastname: Yu
authors.affiliation: Department of Chemistry, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, P. R. China. hfding@zju.edu.cn.
authors.forename: Beiling
authors.initials: B
authors.lastname: Gao
authors.affiliation: Department of Chemistry, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, P. R. China. hfding@zju.edu.cn.
authors.forename: Zhaobo
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Zhejiang University, 866 Yuhangtang Road, Hangzhou 310058, P. R. China. hfding@zju.edu.cn.
authors.forename: Hanfeng
authors.initials: H
authors.lastname: Ding