title: Small RAB GTPases Regulate Multiple Steps of Mitosis.
abstract: GTPases of the RAB family are key regulators of multiple steps of membrane trafficking. Several members of the RAB GTPase family have been implicated in mitotic progression. In this review, we will first focus on the function of endosome-associated RAB GTPases reported in early steps of mitosis, spindle pole maturation, and during cytokinesis. Second, we will discuss the role of Golgi-associated RAB GTPases at the metaphase/anaphase transition and during cytokinesis.
authors.affiliation: Institut Curie, PSL Research University, Molecular Mechanisms of Intracellular Transport Group, CNRS UMR 144 Paris, France.
authors.forename: Stéphanie
authors.initials: S
authors.lastname: Miserey-Lenkei
authors.affiliation: Laboratorio de Biología Celular y Molecular, Instituto de Histología y Embriología-CONICET, Facultad de Ciencias Médicas, Universidad Nacional de Cuyo Mendoza, Argentina.
authors.forename: María I
authors.initials: MI
authors.lastname: Colombo
keywords: RABs GTPases; endosomes; golgi complex; mitosis; trafficking