title: Quality of Life Assessment After Maxillomandibular Advancement Surgery for Obstructive Sleep Apnea.
abstract: OBJECTIVE
  Although maxillomandibular advancement (MMA) surgery is highly efficacious for the management of obstructive sleep apnea (OSA), little information exists regarding the subjective effect of this treatment modality. The present study was undertaken to investigate the effect of MMA on patient-perceived quality of life (QOL) in OSA.
  
  
  METHODS
  A retrospective cohort study of patients treated with MMA for OSA from May 2010 to April 2015 was performed. The primary outcome measure was a change in the QOL detected using the Ottawa Sleep Apnea Questionnaire (OSA-Q), which assesses the MMA-related changes in QOL with a 5-point Likert scale. The secondary outcome measure was a change in the apnea hypopnea index (AHI).
  
  
  RESULTS
  Twenty-two patients participated in the present study. The mean maxillary and mandibular advancement were 8.36 and 11.08 mm, respectively. The AHI decreased from 42.4 to 6.9 events per hour postoperatively (P < .001). The QOL improved significantly after MMA (OSA-Q score 3.98 ± 0.35; P < 001). The sleep quality (4.35 ± 0.63), daytime function (4.13 ± 0.46), physical health (4.19 ± 0.45), mental and emotional health (4.02 ± 0.55), and sexual health (3.78 ± 0.62) categories all improved postoperatively (P < .001). The MMA-related side effects did not adversely affect the QOL.
  
  
  CONCLUSIONS
  MMA for OSA significantly improves patient's subjective overall QOL, with few MMA-related side effects.
authors.affiliation: Chief, Division of Dentistry/Oral and Maxillofacial Surgery, Ottawa Hospital, and Assistant Professor, Department of Otolaryngology, University of Ottawa School of Medicine, Ottawa, Ontario, Canada. Electronic address: kbutterfield@argyleassociates.com.
authors.forename: Kevin J
authors.initials: KJ
authors.lastname: Butterfield
authors.affiliation: Medical Student, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Patricia L G
authors.initials: PL
authors.lastname: Marks
authors.affiliation: Assistant Professor, Department of Otolaryngology, University of Ottawa School of Medicine, Ottawa, Ontario, Canada.
authors.forename: Laurie
authors.initials: L
authors.lastname: McLean
authors.affiliation: Research Assistant, Division of Dentistry/Oral and Maxillofacial Surgery, Ottawa Hospital, Ottawa, Ontario, Canada.
authors.forename: Jack
authors.initials: J
authors.lastname: Newton
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement; D008875:Middle Aged; D019340:Osteotomy, Le Fort; D059229:Osteotomy, Sagittal Split Ramus; D011788:Quality of Life; D020181:Sleep Apnea, Obstructive / Q000601:surgery*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome