title: MdSOS2L1 forms a complex with MdMYB1 to control vacuolar pH by transcriptionally regulating MdVHA-B1 in apples.
abstract: Vacuolar pH is important and involves in many different physiological processes in plants. A recent paper published in Plant Physiology reveals that MdMYB1 regulates vacuolar pH by directly transcriptionally regulating proton pump genes and malate transporters genes, such as V-ATPase subunit gene MdVHA-B1. Here, we found that MdSOS2L1 in vitro did not directly interact with MdMYB1, however, in vivo formed a complex with MdMYB1 in the nucleus to regulate MdVHA-B1-mediated vacuolar acidification. This finding shed light on the role of MdSOS2L1 in transcriptionally regulating MdVHA-B1 in addition to its post-modified function in apples.
authors.affiliation: a State Key Laboratory of Crop Biology, National Research Center for Apple Engineering and Technology, College of Horticulture Science and Engineering, Shandong Agricultural University , Tai-An, Shandong China.
authors.forename: Cui-Hui
authors.initials: CH
authors.lastname: Sun
authors.affiliation: a State Key Laboratory of Crop Biology, National Research Center for Apple Engineering and Technology, College of Horticulture Science and Engineering, Shandong Agricultural University , Tai-An, Shandong China.
authors.forename: Quan-Yan
authors.initials: QY
authors.lastname: Zhang
authors.affiliation: a State Key Laboratory of Crop Biology, National Research Center for Apple Engineering and Technology, College of Horticulture Science and Engineering, Shandong Agricultural University , Tai-An, Shandong China.
authors.forename: Mei-Hong
authors.initials: MH
authors.lastname: Sun
authors.affiliation: a State Key Laboratory of Crop Biology, National Research Center for Apple Engineering and Technology, College of Horticulture Science and Engineering, Shandong Agricultural University , Tai-An, Shandong China.
authors.forename: Da-Gang
authors.initials: DG
authors.lastname: Hu
mesh_terms: D001692:Biological Transport; D018506:Gene Expression Regulation, Plant; D006863:Hydrogen-Ion Concentration; D008293:Malates / Q000378:metabolism*; D027845:Malus / Q000737:chemistry / Q000378:metabolism*; D010766:Phosphorylation; D010940:Plant Proteins / Q000032:analysis / Q000378:metabolism / Q000502:physiology*; D011494:Protein Kinases / Q000032:analysis / Q000502:physiology*; D011993:Recombinant Fusion Proteins / Q000032:analysis; D015398:Signal Transduction
chemical_list: D008293:Malates; D010940:Plant Proteins; D011993:Recombinant Fusion Proteins; C030298:malic acid; D011494:Protein Kinases
keywords: Apple; MdMYB1; MdSOS2L1; MdVHA-B1; vacuolar pH