title: Development and Validation of the Short Crohn's Disease Work Disability Questionnaire.
abstract: BACKGROUND
  The aim was to develop and validate a self-reported short Crohn's disease work disability questionnaire (sCDWDQ).
  
  
  METHODS
  (1) Development of a shortened questionnaire-Patients' responses to the validation process (n = 108) of a previously developed, 16-item Spanish Crohn's disease work disability questionnaire (CDWDQ) were analyzed using the Rasch model for multiple response items. After this process, a 9-item sCDWDQ was obtained. (2) Validation phase-The validation assessed the questionnaire's convergent validity, discriminant validity, test-retest reproducibility, and internal consistency. Spearman rank correlation, t test, intra-class correlation and Cronbach's alpha were used for the analysis.
  
  
  RESULTS
  One hundred fifty-one patients were included in the validation phase. (1) Convergent validity was confirmed by correlations between the sCDWDQ and clinical activity (r = 0.66, P < 0.01), the short inflammatory bowel disease questionnaire IBDQ-9 (r = 0.74, P < 0.001), Euroqol-5D (r = 0.63, P < 0.01), the EuroQol-5D visual analog scale (r = 0.54, P < 0.01), and overall work impairment (r = 0.66, P < 0.01); (2) Discriminant validity-sCDWDQ scores were higher in patients with active disease (20.1 ± 6.3 versus 13.0 ± 3.8 inactive, P < 0.001), in those requiring previous sick leave (19.6 ± 6.9 versus no sick leave 14.2 ± 4.8, P < 0.01) and in those requiring hospitalization (20.0 ± 7.3 [n = 29] versus no hospitalization 14.1 ± 7.3 [n = 90], P < 0.01); (3) Internal consistency was also good (Cronbach's alpha = 0.92); and (4) Reproducibility-sCDWDQ measures obtained 2 weeks apart showed an excellent intraclass correlation coefficient of 0.92 (95% confidence interval, 0.90-0.94).
  
  
  CONCLUSIONS
  The self-reported sCDWDQ appears to be a simple, valid, and reliable tool for measuring work disability in Crohn's disease.
authors.affiliation: *Servei Aparell Digestiu, Corporació Sanitària Universitària Parc Tauli, Sabadell, Barcelona, Spain; †Departament de Medicina, Universitat Autònoma de Barcelona, Spain; ‡CIBERehd, Instituto de Salud Carlos III, Madrid, Spain; §Servicio de Aparato Digestivo, Complejo Asistencial de Burgos, Burgos, Spain; ‖Faculty of Public Health and Policy, London School of Hygiene and Tropical Medicine, London, United Kingdom; ¶Servei d'Aparell Digestiu Hospital Vall d'Hebron, Universitat Autònoma de Barcelona, Barcelona, Spain; and **Servicio de AparatoDigestivo, Hospital Clínico Universitario de Zaragoza, Zaragoza, Spain.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Vergara
authors.forename: Beatriz
authors.initials: B
authors.lastname: Sicilia
authors.forename: Luis
authors.initials: L
authors.lastname: Prieto
authors.forename: Francesc
authors.initials: F
authors.lastname: Casellas
authors.forename: Alexis
authors.initials: A
authors.lastname: Ramos
authors.forename: Fernando
authors.initials: F
authors.lastname: Gomollón
authors.forename: Xavier
authors.initials: X
authors.lastname: Calvet
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003424:Crohn Disease / Q000175:diagnosis* / Q000523:psychology*; D006233:Persons with Disabilities / Q000523:psychology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010465:Perception; D011594:Psychometrics; D011788:Quality of Life; D012720:Severity of Illness Index; D018582:Sick Leave; D011795:Surveys and Questionnaires; D014938:Work Capacity Evaluation; D055815:Young Adult