title: Fluorescent and Magnetic Mesoporous Hybrid Material: A Chemical and Biological Nanosensor for Hg(2+) Ions.
abstract: We introduce "sense, track and separate" approach for the removal of Hg(2+) ion from aqueous media using highly ordered and magnetic mesoporous ferrosilicate nanocages functionalised with rhodamine fluorophore derivative. These functionalised materials offer both fluorescent and magnetic properties in a single system which help not only to selectively sense the Hg(2+) ions with a high precision but also adsorb and separate a significant amount of Hg(2+) ion in aqueous media. We demonstrate that the magnetic affinity of these materials, generated from the ultrafine γ-Fe2O3 nanoparticles present inside the nanochannels of the support, can efficiently be used as a fluorescent tag to sense the Hg(2+) ions present in NIH3T3 fibroblasts live cells and to track the movement of the cells by external magnetic field monitored using confocal fluorescence microscopy. This simple approach of introducing multiple functions in the magnetic mesoporous materials raise the prospect of creating new advanced functional materials by fusing organic, inorganic and biomolecules to create advanced hybrid nanoporous materials which have a potential use not only for sensing and the separation of toxic metal ions but also for cell tracking in bio-separation and the drug delivery.
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.|School of Chemistry and Molecular Biosciences (SCMB), The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Moorthy
authors.initials: M
authors.lastname: Suresh
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Chokkalingam
authors.initials: C
authors.lastname: Anand
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Jessica E
authors.initials: JE
authors.lastname: Frith
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Dattatray S
authors.initials: DS
authors.lastname: Dhawale
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Vishnu P
authors.initials: VP
authors.lastname: Subramaniam
authors.affiliation: Centre for Advanced Imaging (CAI), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Ekaterina
authors.initials: E
authors.lastname: Strounina
authors.affiliation: Superconducting Properties Unit, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.
authors.forename: Clastinrusselraj I
authors.initials: CI
authors.lastname: Sathish
authors.affiliation: Superconducting Properties Unit, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.
authors.forename: Kazunari
authors.initials: K
authors.lastname: Yamaura
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.
authors.forename: Justin J
authors.initials: JJ
authors.lastname: Cooper-White
authors.affiliation: Australian Institute for Bioengineering and Nanotechnology (AIBN), Cnr Cooper and College Rd, The University of Queensland, St. Lucia, Queensland 4072, Australia.|Future Industries Institute, University of South Australia, Mawson Lakes 5095, SA, Australia.
authors.forename: Ajayan
authors.initials: A
authors.lastname: Vinu
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes / Q000737:chemistry; D007477:Ions / Q000737:chemistry; D058185:Magnetite Nanoparticles / Q000737:chemistry; D008628:Mercury / Q000032:analysis*; D008670:Metals / Q000737:chemistry; D051379:Mice; D008856:Microscopy, Fluorescence; D041681:NIH 3T3 Cells; D049329:Nanostructures / Q000737:chemistry*; D016062:Porosity; D012235:Rhodamines / Q000737:chemistry; D012821:Silanes / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D014961:X-Ray Diffraction
chemical_list: C548971:3-chloropropyltrimethoxysilane; D005456:Fluorescent Dyes; D007477:Ions; D058185:Magnetite Nanoparticles; D008670:Metals; D012235:Rhodamines; D012821:Silanes; D008628:Mercury