title: Manipulation of partially oriented hydroxyapatite building blocks to form flowerlike bundles without acid-base regulation.
abstract: The application of hydroxyapatite (HAP) in different fields depends greatly on its morphology, composition and structure. Besides, the main inorganic building blocks of human bones and teeth are also HAP. Therefore, accurate shape and aggregation control and of hydroxyapatite particles will be of great interest. Herein, oriented bundles of flowerlike HAP nanorods were successfully prepared through hydrothermal treatment without acid-base regulation, with the mono-alkyl phosphate (MAP) and sodium citrate as surfactant and chelating agent, respectively. The prepared samples were characterized by the X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), high-resolution transmission electron microscopy (HRTEM) and zeta potential, the pH value and conductivity value of suspension were characterized by pH meter and conductivity measurement. The results showed that the MAP and citrate play an important role in assembly of HAP nanorods without acid-base regulation. Citrate calcium complex could decompose slowly and release citrate ions at hydrothermal conditions. Besides, the further decomposition of citrate ions could release aconitic acid as the reaction time prolongs. Moreover, the possible scheme for the formation process was discussed in detail.
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China.
authors.forename: Zhenliang
authors.initials: Z
authors.lastname: Wen
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China.
authors.forename: Zihao
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China. Electronic address: ibptcjd@fzu.edu.cn.
authors.forename: Jingdi
authors.initials: J
authors.lastname: Chen
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China.
authors.forename: Shengnan
authors.initials: S
authors.lastname: Zhong
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China.
authors.forename: Yimin
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
authors.affiliation: Institute of Biomedical and Pharmaceutical Technology, Fuzhou University, Fuzhou 350002, China; Institute of Biomedical Engineering, Chinese Academy of Medical Science and Peking Union Medical College, Tianjin 300192, China. Electronic address: zhangqiq@126.com.
authors.forename: Qiqing
authors.initials: Q
authors.lastname: Zhang
mesh_terms: D000327:Adsorption; D017610:Calcium Compounds / Q000737:chemistry; D002614:Chelating Agents / Q000737:chemistry*; D002951:Citrates / Q000737:chemistry*; D017886:Durapatite / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D046529:Microscopy, Electron, Transmission; D043942:Nanotubes; D009566:Nitrates / Q000737:chemistry; D010710:Phosphates / Q000737:chemistry; D000077559:Sodium Citrate; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013501:Surface-Active Agents / Q000737:chemistry*
chemical_list: D017610:Calcium Compounds; D002614:Chelating Agents; D002951:Citrates; D009566:Nitrates; D010710:Phosphates; D013501:Surface-Active Agents; C024788:ammonium phosphate; D000077559:Sodium Citrate; D017886:Durapatite; C059948:calcium nitrate
keywords: Bone-like structure; Chelating agent; Hydroxyapatite; Shape control; Surfactant