title: [Advanced Adenocarcinoma of the Bladder after Augmentation Gastrocystoplasty].
abstract: A 29-year-old woman had undergone gastrocystoplasty with Mitrofanoff appendicovesicostomy for urethral trauma at 9 years of age. Since then, she was being followed up for performing clean intermittent self-catheterization at regular intervals. Twenty years after the surgery, she presented with gross hematuria. Ultrasonographic findings revealed bilateral hydronephrosis. Cystoscopy and computed tomography (CT) revealed invasive bladder cancer with pelvic lymph node metastases. A biopsy confirmed the diagnosis of adenocarcinoma with signet ring cell carcinoma. Subsequently, neo-adjuvant combination chemotherapy with TS-1 and cisplatin (CDDP) was initiated, which was followed by open radical cystectomy with extended pelvic lymphadenectomy. The tumor was found to infiltrate from the anastomotic site into the entire native bladder and histopathological diagnosis was muscle invasive adenocarcinoma with neuroendocrine differentiation and lymph node metastasis (ypT3bN2). TS-1 was continued as adjuvant chemotherapy and the patient did not have any evidence of recurrence for 12 months postoperatively.
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Yuka
authors.initials: Y
authors.lastname: Kono
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Naoki
authors.initials: N
authors.lastname: Terada
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Takashima
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Kensuke
authors.initials: K
authors.lastname: Hikami
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Takuya
authors.initials: T
authors.lastname: Hida
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Shuhei
authors.initials: S
authors.lastname: Goto
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Takuro
authors.initials: T
authors.lastname: Sunada
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Okada
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Noboru
authors.initials: N
authors.lastname: Shibasaki
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Negoro
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kobayashi
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Toshinari
authors.initials: T
authors.lastname: Yamasaki
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Matsui
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Inoue
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Kamba
authors.affiliation: The Department of Urology, Kyoto University Graduate School of Medicine.
authors.forename: Osamu
authors.initials: O
authors.lastname: Ogawa
mesh_terms: D000230:Adenocarcinoma; D000328:Adult; D001706:Biopsy; D003559:Cystostomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D009367:Neoplasm Staging; D013270:Stomach / Q000601:surgery*; D001749:Urinary Bladder Neoplasms / Q000473:pathology* / Q000601:surgery