title: Mental Health and Health-Related Quality of Life in Multiple Sclerosis Caregivers in Mexico.
abstract: BACKGROUND
  Multiple sclerosis (MS) rates are increasing in Latin America, and caregiving for an individual with MS is associated with poorer mental and physical health outcomes. No existing research has examined the relation between mental health and health-related quality of life (HRQOL) in MS caregivers in Latin America.
  
  
  METHODS
  The present study examined the association between mental health (Patient Health Questionnaire-9, Satisfaction with Life Scale, Rosenberg Self-esteem Scale, State-Trait Anxiety Inventory) and HRQOL (36-item Short Form Health Status Survey) in 81 Mexican MS caregivers.
  
  
  RESULTS
  A canonical correlation analysis uncovered a large, significant overall association between mental health and HRQOL, with 52.7% of the variance shared between the two sets of constructs. When individual canonical loadings were examined in this analysis, the most substantial pattern that emerged was between depression and general health. Four regressions controlling for demographic variables found that HRQOL uniquely accounted for 19.0% of the variance in caregiver anxiety, 32.5% in depression, 13.5% in satisfaction with life, and 14.3% in self-esteem.
  
  
  CONCLUSIONS
  These findings demonstrated a strong association between HRQOL and mental health, which points to directions for future studies on interventions for MS caregivers, particularly in Mexican and other Latino populations.
authors.affiliation: Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA (GGL); Department of Child & Family Studies, Rehabilitation & Mental Health Counseling Program, University of South Florida, Tampa, FL, USA (MS); Department of Neuroscience, University of Guadalajara, Guadalajara, Mexico (MAMI); Department of Research, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (AAA); and Department of Psychology, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (BVRB).
authors.forename: Gillian G
authors.initials: GG
authors.lastname: Leibach
authors.affiliation: Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA (GGL); Department of Child & Family Studies, Rehabilitation & Mental Health Counseling Program, University of South Florida, Tampa, FL, USA (MS); Department of Neuroscience, University of Guadalajara, Guadalajara, Mexico (MAMI); Department of Research, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (AAA); and Department of Psychology, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (BVRB).
authors.forename: Marilyn
authors.initials: M
authors.lastname: Stern
authors.affiliation: Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA (GGL); Department of Child & Family Studies, Rehabilitation & Mental Health Counseling Program, University of South Florida, Tampa, FL, USA (MS); Department of Neuroscience, University of Guadalajara, Guadalajara, Mexico (MAMI); Department of Research, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (AAA); and Department of Psychology, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (BVRB).
authors.forename: Adriana Aguayo
authors.initials: AA
authors.lastname: Arelis
authors.affiliation: Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA (GGL); Department of Child & Family Studies, Rehabilitation & Mental Health Counseling Program, University of South Florida, Tampa, FL, USA (MS); Department of Neuroscience, University of Guadalajara, Guadalajara, Mexico (MAMI); Department of Research, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (AAA); and Department of Psychology, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (BVRB).
authors.forename: Miguel Angel Macias
authors.initials: MA
authors.lastname: Islas
authors.affiliation: Department of Psychology, Virginia Commonwealth University, Richmond, VA, USA (GGL); Department of Child & Family Studies, Rehabilitation & Mental Health Counseling Program, University of South Florida, Tampa, FL, USA (MS); Department of Neuroscience, University of Guadalajara, Guadalajara, Mexico (MAMI); Department of Research, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (AAA); and Department of Psychology, Universidad Enrique Diaz de Leon, Guadalajara, Mexico (BVRB).
authors.forename: Brenda Viridiana Rábago
authors.initials: BV
authors.lastname: Barajas