title: Transplantation of Simian Mesenchymal Stem Cells to Baboons with Experimentally Induced Myocardial Infarction.
abstract: Culture of mesenchymal stem cells isolated from the bone marrow of primates by their characteristics met the requirements of stem cells. It was shown that transplantation of allogeneic mesenchymal stem cells (2 million cells per 1 kg body weight) immediately after ligation of the left anterior descending coronary artery between the middle and upper thirds led to neovascularization and capillarization of the ischemic myocardium.
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia. agrba_vz@mail.ru.
authors.forename: V Z
authors.initials: VZ
authors.lastname: Agrba
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: V A
authors.initials: VA
authors.lastname: Porkhanov
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: D D
authors.initials: DD
authors.lastname: Karal-Ogly
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Leontyuk
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: A L
authors.initials: AL
authors.lastname: Kovalenko
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: I Yu
authors.initials: IY
authors.lastname: Sholin
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: T E
authors.initials: TE
authors.lastname: Gvozdik
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: I E
authors.initials: IE
authors.lastname: Ignatova
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Agumava
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: Yu P
authors.initials: YP
authors.lastname: Chuguev
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Gvaramiya
authors.affiliation: Research Institute of Medical Primatology, Sochi, Russia.
authors.forename: B A
authors.initials: BA
authors.lastname: Lapin
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology; D064987:Cell- and Tissue-Based Therapy / Q000379:methods*; D003331:Coronary Vessels / Q000601:surgery; D008297:Male; D045164:Mesenchymal Stem Cell Transplantation; D059630:Mesenchymal Stem Cells / Q000166:cytology*; D009203:Myocardial Infarction / Q000628:therapy*; D018919:Neovascularization, Physiologic / Q000502:physiology*; D010215:Papio
keywords: cell therapy; myocardial infarction; primates; stem cells