title: Treatments for post-menopausal osteoporotic women, what's new? How can we manage long-term treatment?
abstract: Since the mid-1980s, postmenopausal osteoporosis (PMO) has been considered a serious public health concern because of the associated fractures. Pharmacological therapies that effectively reduce the number of fractures by improving bone mass have been and are being developed continuously. Most current agents inhibit bone loss by reducing bone resorption, but emerging therapies may increase bone mass by stimulating bone formation. Furthermore, nowadays, the most representative pharmaceuticals have been prescribed long enough to include the reporting of some adverse effects. This review discusses osteoporotic drugs that are approved or are under investigation for the treatment of post-menopausal women (PMW), paying particular attention to long-term treatments.
authors.affiliation: Food and Environmental Research Group (SAMA-UV), Department of Preventive Medicine, Faculty of Pharmacy, University of Valencia, Vicent Andrés Estellés Avenue, Burjassot 46100, València, Spain. Electronic address: sohero@hotmail.com.
authors.forename: Soledad
authors.initials: S
authors.lastname: Herrero
authors.affiliation: Food and Environmental Research Group (SAMA-UV), Department of Preventive Medicine, Faculty of Pharmacy, University of Valencia, Vicent Andrés Estellés Avenue, Burjassot 46100, València, Spain.
authors.forename: Yolanda
authors.initials: Y
authors.lastname: Pico
mesh_terms: D005260:Female; D006801:Humans; D015663:Osteoporosis, Postmenopausal / Q000188:drug therapy*; D013997:Time Factors
keywords: Bisphosphonate; Cathepsin K; Denosumab; Long-term-Treatment; Postmenopausal Osteoporosis; Romosozumab