title: Chemical Constituents of Plants from the Genus Phlegmariurus.
abstract: Phlegmariurus is a genus of ca. 200 species in the family Huperziaceae. Up to now, six species of the Phlegmariurus genus have been chemically investigated, and 89 compounds, including Lycopodium alkaloids possessing diverse structures and serratane-type triterpenes, have been isolated. These compounds show potent bioactivities, such as acetylcholinesterase inhibitory and cytotoxic activities.
authors.affiliation: School of Chemistry and Chemical Engineering, Yunnan Normal University, Chenggong New District, Kunming, 650500, P. R. China.
authors.forename: Yiyu
authors.initials: Y
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering, Yunnan Normal University, Chenggong New District, Kunming, 650500, P. R. China.
authors.forename: Zhichong
authors.initials: Z
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Yunnan Normal University, Chenggong New District, Kunming, 650500, P. R. China.
authors.forename: Jichun
authors.initials: J
authors.lastname: Wu
authors.affiliation: School of Chemistry and Chemical Engineering, Yunnan Normal University, Chenggong New District, Kunming, 650500, P. R. China.
authors.forename: Yegao
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000110:Acetylcholinesterase / Q000378:metabolism; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D049109:Cell Proliferation / Q000187:drug effects; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D004305:Dose-Response Relationship, Drug; D006801:Humans; D032501:Huperzia / Q000737:chemistry*; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D013329:Structure-Activity Relationship; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*
chemical_list: D000470:Alkaloids; D002800:Cholinesterase Inhibitors; D010936:Plant Extracts; D014315:Triterpenes; D000110:Acetylcholinesterase
keywords: Biological activity; Huperziaceae; Lycopodium alkaloids; Phlegmariurus; Serratane-type triterpenes