title: Rotating for elongation: Fat2 whips for the race.
abstract: Dynamic rearrangements of the actin cytoskeleton are crucial for cell shape and migration. In this issue, Squarr et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201508081) show that the cadherin superfamily protein Fat2 regulates actin-rich protrusions driving collective cell migration during Drosophila melanogaster egg morphogenesis through its interaction with the WAVE regulatory complex.
authors.affiliation: Dendrite Differentiation, German Center for Neurodegenerative Diseases, 53115 Bonn, Germany.
authors.forename: Tomke
authors.initials: T
authors.lastname: Stürner
authors.affiliation: Dendrite Differentiation, German Center for Neurodegenerative Diseases, 53115 Bonn, Germany gaia.tavosanis@dzne.de.
authors.forename: Gaia
authors.initials: G
authors.lastname: Tavosanis
mesh_terms: D000818:Animals; D015820:Cadherins / Q000378:metabolism*; D002465:Cell Movement; D029721:Drosophila Proteins / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000166:cytology* / Q000378:metabolism*; D046912:Multiprotein Complexes / Q000378:metabolism*
chemical_list: D015820:Cadherins; D029721:Drosophila Proteins; D046912:Multiprotein Complexes