title: [Analysis of 113 cases with mucinous cystic neoplasms in a single institutional study].
abstract: OBJECTIVE
  To describe the clinicopathological characteristics and prognostic factors of mucinous cystic neoplasm(MCN).
  
  
  METHODS
  One hundred and thirteen patients with MCN comfirmed by histological examination admitted in People's Liberation Army General Hospital from January 1994 to June 2015 were analyzed, including 21 male and 92 female patients with mean age of (50.2±14.5) years. Forty-eight patients had incidental discovery of their cystic neoplasm for another reason, 65 patients were symptomatic, and abdominal pain or distension was main clinical symptom. Among 113 patients with MCN, 75 cases were MCN with dysplasia, and 38 cases were MCN with invasive carcinoma. Wilcoxon test and χ(2) test, et al were used to analyzed the data, respectively.
  
  
  RESULTS
  MCN was mostly located in body and tail of pancreas.Sex, mean age, clinical symptom, tumor size, and CA19-9 showed significant difference between MCN with dysplasia and MCN with invasive carcinoma (all P<0.05). The presence of a solid component (χ(2)=32.460, P=0.000)and main pancreatic duct dilation(χ(2)= 5.729, P=0.022) were significantly associated with malignancy. Fifty-eight patients with dysplasia were followed up, only one patient occurred tumor recurrence. Thirty-one patients with malignancy were followed up, among which there were 22 patients dead, 1-, 3-, 5-year survival of MCN with malignancy was 76.9%, 56.5%, 36.6%, respectively. Lymphatic metastasis and tumor recurrence were important prognostic factors of MCN with malignancy(both P<0.05).
  
  
  CONCLUSIONS
  MCN is most affected by old female with no specific symptom, most tumors are located at the body and tail of the pancreas.MCN with dysplasia have excellent prognosis underwent surgery. Even with complete resection, the long-term survival of MCN with malignancy is not satisfied.
authors.affiliation: Department of Hepatobiliary Surgery, People's Liberation Army General Hospital, Beijing 100853, China.
authors.forename: M Y
authors.initials: MY
authors.lastname: Xu
authors.forename: X J
authors.initials: XJ
authors.lastname: Shi
authors.forename: F
authors.initials: F
authors.lastname: Lu
authors.forename: T
authors.initials: T
authors.lastname: Wan
authors.forename: H G
authors.initials: HG
authors.lastname: Wang
authors.forename: M Y
authors.initials: MY
authors.lastname: Chen
authors.forename: L
authors.initials: L
authors.lastname: He
authors.forename: H D
authors.initials: HD
authors.lastname: Shi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D018297:Neoplasms, Cystic, Mucinous, and Serous / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D010179:Pancreas / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery; D011379:Prognosis