title: Hyperspectral optical diffraction tomography.
abstract: Here, we present a novel microscopic technique for measuring wavelength-dependent three-dimensional (3-D) distributions of the refractive indices (RIs) of microscopic samples in the visible wavelengths. Employing 3-D quantitative phase microscopy techniques with a wavelength-swept source, 3-D RI tomograms were obtained in the range of 450 - 700 nm with a spectral resolution of a few nanometers. The capability of the technique was demonstrated by measuring the hyperspectral 3-D RI tomograms of polystyrene beads, human red blood cells, and hepatocytes. The results demonstrate the potential for label-free molecular specific 3-D tomography of biological samples.
authors.forename: JaeHwang
authors.initials: J
authors.lastname: Jung
authors.forename: Kyoohyun
authors.initials: K
authors.lastname: Kim
authors.forename: Jonghee
authors.initials: J
authors.lastname: Yoon
authors.forename: YongKeun
authors.initials: Y
authors.lastname: Park
mesh_terms: D045744:Cell Line, Tumor; D004912:Erythrocytes / Q000166:cytology; D006801:Humans; D021621:Imaging, Three-Dimensional; D008029:Lighting; D041622:Tomography, Optical / Q000379:methods*