title: Tonic-Clonic Seizure following Cytoreductive Surgery with Intraperitoneal Oxaliplatin: A Case Report and Review of the Literature.
abstract: Cytoreductive surgery (CRS) with hyperthermic intraperitoneal (IP) chemotherapy (HIPEC) is believed to improve outcomes in well-selected patients with peritoneal carcinomatosis. However, morbidity and mortality rates associated with this procedure are substantial. Here, we describe the case of a previously healthy young man who underwent CRS with hyperthermic IP oxaliplatin and developed one episode of tonic-clonic seizure on the second postoperative day.
authors.affiliation: Department of Medical Oncology, Hospital São José, São Paulo, Brazil.
authors.forename: Jessica Sayuri
authors.initials: JS
authors.lastname: Tsukamoto
authors.affiliation: Department of Surgical Oncology, Hospital São José, São Paulo, Brazil.
authors.forename: Marcos
authors.initials: M
authors.lastname: Belotto de Oliveira
authors.affiliation: Department of Medical Oncology, Hospital São José, São Paulo, Brazil.
authors.forename: Renata D'alpino
authors.initials: RD
authors.lastname: Peixoto
keywords: Cytoreductive surgery; Intraperitoneal chemotherapy; Oxaliplatin; Peritoneal carcinomatosis; Seizure