title: Nanoporous Carbons Derived from Metal-Organic Frameworks as Novel Matrices for Surface-Assisted Laser Desorption/Ionization Mass Spectrometry.
abstract: Surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) represents a powerful tool for the analysis of biomolecules, synthetic polymers, and even small organic compounds; its performances largely depend on the type of matrix materials utilized. Here, for the first time the employment of nanoporous carbons derived from metal-organic frameworks (MOFs) as novel matrices for SALDI-MS is demonstrated. The nanoporous carbons derived from MOFs not only circumvent the shortcomings of existing matrix materials but also demonstrate much higher efficiency of laser desorption/ionization for various compounds than any other nanoporous carbons reported so far. A new perspective for the development of matrix materials for SALDI-MS application is therefore provided.
authors.affiliation: Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung-Li, 320, Taiwan.
authors.forename: Yung-Han
authors.initials: YH
authors.lastname: Shih
authors.affiliation: Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung-Li, 320, Taiwan.
authors.forename: Chien-Ping
authors.initials: CP
authors.lastname: Fu
authors.affiliation: Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung-Li, 320, Taiwan.
authors.forename: Wan-Ling
authors.initials: WL
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung-Li, 320, Taiwan.
authors.forename: Chia-Her
authors.initials: CH
authors.lastname: Lin
authors.affiliation: Department of Chemistry, Chung Yuan Christian University, 200 Chung Pei Road, Chung-Li, 320, Taiwan.
authors.forename: Hsi-Ya
authors.initials: HY
authors.lastname: Huang
authors.affiliation: Department of Chemistry, University of South Florida, 4202 East Fowler Avenue, Tampa, FL, 33620, USA.
authors.forename: Shengqian
authors.initials: S
authors.lastname: Ma
mesh_terms: D000327:Adsorption; D002244:Carbon / Q000737:chemistry*; D057927:Hydrophobic and Hydrophilic Interactions; D008670:Metals / Q000737:chemistry*; D058608:Nanopores / Q000648:ultrastructure; D009930:Organic Chemicals / Q000737:chemistry*; D056951:Photoelectron Spectroscopy; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*; D013059:Spectrum Analysis, Raman; D013227:Steam; D013696:Temperature; D014961:X-Ray Diffraction
chemical_list: D008670:Metals; D009930:Organic Chemicals; D013227:Steam; D002244:Carbon
keywords: laser chemistry; mass spectrometry; metal-organic frameworks; nanoporous carbons; nanostructures