title: Hypertrophic Cardiomyopathy as a Clinical Component of Congenital Cytomegalovirus Infection.
abstract: We report hypertrophic cardiomyopathy in a newborn with congenital cytomegalovirus infection. The neonate had distinct signs of congenital cytomegalovirus infection including petechiae, jaundice, intracranial calcifications, cerebral ventriculomegaly and chorioretinitis together with hypertrophic cardiomyopathy. Following determination of anti-cytomegalovirus IgM, viral DNA was also isolated from the plasma of the patient by polymerase chain reaction. Although cytomegalovirus is a relatively frequent cause of myocarditis in childhood, it was rarely reported to be associated with cardiac abnormalities such as structural heart disease, atrioventricular block, or dilated cardiomyopathy. To our knowledge, this is the first case with congenital cytomegalovirus infection and hypertrophic cardiomyopathy.
authors.affiliation: Department of Pediatric Cardiology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Demir
authors.affiliation: Department of Pediatric Cardiology, Behçet Uz Children's Hospital, Izmir, Turkey.
authors.forename: M M
authors.initials: MM
authors.lastname: Yilmazer
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Dalli
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: I
authors.initials: I
authors.lastname: Yolbaş
authors.affiliation: Department of Pediatrics, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: U
authors.initials: U
authors.lastname: Uluca
authors.affiliation: Department of Pediatric Cardiology, Faculty of Medicine, Dicle University, Diyarbakır, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Bilici
authors.affiliation: Department of Pediatric Neurology, Diyarbakır Teaching and Research Hospital, Diyarbakır, Turkey, e-mail: turan78tr@hotmail.com.
authors.forename: M I
authors.initials: MI
authors.lastname: Turan
keywords: Congenital; cytomegalovirus; hypertrophic cardiomyopathy