title: Revisiting Management of Pediatric Brain Tumors with New Molecular Insights.
abstract: Pediatric central nervous system primitive neuro-ectodermal brain tumors (CNS-PNETs) are rare tumors with ill-defined biological features. In this issue of Cell, Sturm et al. used state-of-the-art methods to interrogate these tumors' biology. Their integrated molecular analyses led them to propose a new molecular classification, with four new entities identified, that should get oncologists' attention.
authors.affiliation: Department of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA. Electronic address: wzaky@mdanderson.org.
authors.forename: Wafik
authors.initials: W
authors.lastname: Zaky
mesh_terms: D016543:Central Nervous System Neoplasms / Q000235:genetics* / Q000473:pathology*; D019175:DNA Methylation; D006801:Humans; D017599:Neuroectodermal Tumors / Q000235:genetics* / Q000473:pathology*