title: A Case of Infantile Kyrle-Flegel Disease in a 6-Year-Old Yemeni Girl.
abstract: Kyrle disease (KD) and Flegel disease (FD) are rare variants of primary perforating dermatoses, characterized by transepidermal elimination of abnormal endogenous materials. We describe a 6-year-old Yemeni girl with a 2-year history of generalized asymptomatic, small, reddish-brown keratotic papules with a lenticular central keratotic plug. Although these features are synonymous with FD, the histology of a punch biopsy was consistent with KD. The patient was otherwise healthy, and no family members had a history of similar diseases. The patient was diagnosed with KD-FD, owing to the manifestation of features associated with both diseases.
authors.affiliation: Dermatology Department, University Hospital, Sana'a University, Sana'a, Yemen.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Alshami
authors.affiliation: Dermatology Department, University Hospital, Sana'a University, Sana'a, Yemen.
authors.forename: Mona Jameel
authors.initials: MJ
authors.lastname: Mohana
keywords: Flegel disease; Keratotic plug; Kyrle disease; Nodule; Papule