title: Reply to Lesho.
authors.affiliation: Icahn Institute and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
authors.forename: Theodore R
authors.initials: TR
authors.lastname: Pak
authors.affiliation: Icahn Institute and Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York.
authors.forename: Andrew
authors.initials: A
authors.lastname: Kasarskis
mesh_terms: D003141:Communicable Diseases; D019295:Computational Biology; D019468:Disease Management; D023281:Genomics; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D015201:Meta-Analysis as Topic; D017422:Sequence Analysis, DNA