title: Electrochemical Synthesis of Benzazoles from Alcohols and o-Substituted Anilines with a Catalytic Amount of Co(II) Salt.
abstract: An electrochemical synthesis of benzazoles directly from alcohols and o-substituted anilines has been developed. The reaction conditions have been optimized by varying the composition of the electrolyte and the metal salt used as catalyst. The cyclization proceeds smoothly with a catalytic amount of a cobalt salt under air at room temperature to afford 2-substituted benzimidazoles, benzothiazoles, and benzoxazoles in good to excellent yields with a wide substrate scope.
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, P. R. China.
authors.forename: Yin-Long
authors.initials: YL
authors.lastname: Lai
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, P. R. China.
authors.forename: Jian-Shan
authors.initials: JS
authors.lastname: Ye
authors.affiliation: School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou, Guangdong, 510640, P. R. China. chehjm@scut.edu.cn.
authors.forename: Jing-Mei
authors.initials: JM
authors.lastname: Huang
keywords: alcohols; benzazoles; cobalt; electrochemistry; o-substituted anilines