title: I2/O2-Enabled N-S Bond Formation to Access Functionalized 1,2,3-Thiadiazoles.
abstract: A new, metal-free intermolecular formal [3 + 2] heterocyclization between triethylammonium thiolates and aryl hydrazines has been established by using the combination of I2 and O2 as efficient oxidation sources, allowing a concise and low-cost access to new densely functionalized 1,2,3-thiadiazoles with good to excellent yields. The reaction showed a broad scope of substrates of both reactants and attractive characteristics consisting of eco-friendly oxidants, flexible structural modification, broad functional group compatibility, and mild reaction conditions.
authors.affiliation: Institute of Chemistry & BioMedical Sciences, Nanjing University , Nanjing 210093, P. R. China.
authors.forename: Wei
authors.initials: W
authors.lastname: Fan
authors.affiliation: Institute of Chemistry & BioMedical Sciences, Nanjing University , Nanjing 210093, P. R. China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Li
authors.affiliation: Institute of Chemistry & BioMedical Sciences, Nanjing University , Nanjing 210093, P. R. China.
authors.forename: Yanrong
authors.initials: Y
authors.lastname: Li
authors.affiliation: Institute of Chemistry & BioMedical Sciences, Nanjing University , Nanjing 210093, P. R. China.
authors.forename: Hao
authors.initials: H
authors.lastname: Sun
authors.affiliation: Department of Chemistry and Biochemistry, Texas Tech University , Lubbock, Texas 79409-1061, United States ; and.|School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou, 221116 Jiangsu, P. R. China.
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
authors.affiliation: Institute of Chemistry & BioMedical Sciences, Nanjing University , Nanjing 210093, P. R. China.|Department of Chemistry and Biochemistry, Texas Tech University , Lubbock, Texas 79409-1061, United States ; and.
authors.forename: Guigen
authors.initials: G
authors.lastname: Li
mesh_terms: D002384:Catalysis; D006834:Hydrazines / Q000737:chemistry*; D015394:Molecular Structure; D016877:Oxidants / Q000737:chemistry; D010084:Oxidation-Reduction; D013830:Thiadiazoles / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006834:Hydrazines; D016877:Oxidants; D013830:Thiadiazoles