title: Cytolytic hepatitis related to simeprevir overdose in a patient with cirrhosis and HIV-HCV genotype 1 coinfection.
authors.affiliation: aHepatogastroenterology and Alcohology Unit Departments of bPharmacy cInternal Medicine and Infectious Diseases, GHPSO, Creil dDepartment of Internal Medicine and Infectious Diseases, Hôpital Européen Marseille, Marseille eHepatogastroenterology Unit, CHU Amiens-Picardie, Amiens, France.
authors.forename: Hortensia
authors.initials: H
authors.lastname: Lison
authors.forename: Armand
authors.initials: A
authors.lastname: Garioud
authors.forename: Philippe
authors.initials: P
authors.lastname: Halfon
authors.forename: Samy
authors.initials: S
authors.lastname: Jambon
authors.forename: François
authors.initials: F
authors.lastname: Cordier
authors.forename: Céline
authors.initials: C
authors.lastname: Verbrigghe
authors.forename: Nathalie
authors.initials: N
authors.lastname: Landgraf
authors.forename: Christophe
authors.initials: C
authors.lastname: Pitre
authors.forename: Eric
authors.initials: E
authors.lastname: Nguyen-Khac
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Cadranel
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage / Q000009:adverse effects*; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000209:etiology*; D060085:Coinfection; D062787:Drug Overdose; D057915:Drug Substitution; D004359:Drug Therapy, Combination; D005838:Genotype; D015658:HIV Infections / Q000150:complications* / Q000175:diagnosis; D016174:Hepacivirus / Q000187:drug effects* / Q000235:genetics / Q000472:pathogenicity; D019698:Hepatitis C, Chronic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D006801:Humans; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000821:virology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D011480:Protease Inhibitors / Q000008:administration & dosage / Q000009:adverse effects*; D000069616:Simeprevir / Q000008:administration & dosage / Q000009:adverse effects*; D016896:Treatment Outcome
chemical_list: D000998:Antiviral Agents; D011480:Protease Inhibitors; D000069616:Simeprevir