title: Components of Metabolic Syndrome and the Risk of Disability among the Elderly Population.
abstract: The direct relationship between metabolic syndrome (MetS) and function disability has not been established. The aim of the present study was to investigate the relationship between MetS and functional disability in the elderly. This retrospective observational study included 1,778 participants aged 60-84 years from the National Health and Nutrition Examination Survey (1999-2002). Impairments in activities of daily living (ADL), instrumental activities of daily living (IADL), leisure and social activities (LSA), lower extremity mobility (LEM), and general physical activities (GPA) were assessed. Additionally, the associations between the features of MetS and disability were evaluated. MetS was associated with a high prevalence of functional dependence in ADL, IADL, LSA, LEM, and GPA. After adjusting for potential confounders, a high number of MetS components was found to be associated with increased disability (P = 0.002). Additionally, associations were observed between MetS components, including abdominal obesity and high triglycerides levels, and functional dependence in ADL, IADL, LSA, LEM, and GPA (all, P < 0.05). A linear increase in disability might be associated with the number of MetS components in an elderly population. Additionally, MetS abnormalities, particularly abdominal obesity and high triglycerides levels, might be highly predictive of functional dependence in the elderly.
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Fang-Yih
authors.initials: FY
authors.lastname: Liaw
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Tung-Wei
authors.initials: TW
authors.lastname: Kao
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Li-Wei
authors.initials: LW
authors.lastname: Wu
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Chung-Ching
authors.initials: CC
authors.lastname: Wang
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Hui-Fang
authors.initials: HF
authors.lastname: Yang
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Tao-Chun
authors.initials: TC
authors.lastname: Peng
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Yu-Shan
authors.initials: YS
authors.lastname: Sun
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Yaw-Wen
authors.initials: YW
authors.lastname: Chang
authors.affiliation: Division of Family Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Division of Geriatric Medicine, Department of Family and Community Medicine, Tri-Service General Hospital and School of Medicine, National Defense Medical Center, Taipei, Taiwan(R.O.C).|Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan(R.O.C).
authors.forename: Wei-Liang
authors.initials: WL
authors.lastname: Chen
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D006233:Persons with Disabilities; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications*; D008875:Middle Aged; D012189:Retrospective Studies; D018570:Risk Assessment; D012648:Self Care