title: Genome-wide analyses for dissecting gene regulatory networks in the shoot apical meristem.
abstract: Shoot apical meristem activity is controlled by complex regulatory networks in which components such as transcription factors, miRNAs, small peptides, hormones, enzymes and epigenetic marks all participate. Many key genes that determine the inherent characteristics of the shoot apical meristem have been identified through genetic approaches. Recent advances in genome-wide studies generating extensive transcriptomic and DNA-binding datasets have increased our understanding of the interactions within the regulatory networks that control the activity of the meristem, identifying new regulators and uncovering connections between previously unlinked network components. In this review, we focus on recent studies that illustrate the contribution of whole genome analyses to understand meristem function.
authors.affiliation: Center for Research in Agricultural Genomics (CRAG) CSIC-IRTA-UAB-UB, Cerdanyola del Vallès, 08193 Barcelona, Spain.
authors.forename: Mariana
authors.initials: M
authors.lastname: Bustamante
authors.affiliation: Center for Research in Agricultural Genomics (CRAG) CSIC-IRTA-UAB-UB, Cerdanyola del Vallès, 08193 Barcelona, Spain.
authors.forename: José Tomás
authors.initials: JT
authors.lastname: Matus
authors.affiliation: Center for Research in Agricultural Genomics (CRAG) CSIC-IRTA-UAB-UB, Cerdanyola del Vallès, 08193 Barcelona, Spain Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, 08010, Spain joseluis.riechmann@cragenomica.es.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Riechmann
mesh_terms: D053263:Gene Regulatory Networks; D017343:Genes, Plant; D018745:Genome, Plant; D018519:Meristem / Q000235:genetics*; D018515:Plant Leaves / Q000196:embryology / Q000235:genetics; D013234:Stem Cells / Q000166:cytology / Q000378:metabolism
keywords: Arabidopsis; WUSCHEL.; cell-type specific; shoot apical meristem; stem cell; transcriptome