title: The Sclerotic Scatter Limbal Arc Is More Easily Elicited under Mesopic Rather Than Photopic Conditions.
abstract: BACKGROUND
  We aimed to determine the limbal lighting illuminance thresholds (LLITs) required to trigger perception of sclerotic scatter at the opposite non-illuminated limbus (i.e. perception of a light limbal scleral arc) under different levels of ambient lighting illuminance (ALI).
  
  
  METHODS
  Twenty healthy volunteers were enrolled. The iris shade (light or dark) was graded by retrieving the median value of the pixels of a pre-determined zone of a gray-level iris photograph. Mean keratometry and central corneal pachymetry were recorded. Each subject was asked to lie down, and the ALI at eye level was set to mesopic values (10, 20, 40 lux), then photopic values (60, 80, 100, 150, 200 lux). For each ALI level, a light beam of gradually increasing illuminance was applied to the right temporal limbus until the LLIT was reached, i.e. the level required to produce the faint light arc that is characteristic of sclerotic scatter at the nasal limbus.
  
  
  RESULTS
  After log-log transformation, a linear relationship between the logarithm of ALI and the logarithm of the LLIT was found (p<0.001), a 10% increase in ALI being associated with an average increase in the LLIT of 28.9%. Higher keratometry values were associated with higher LLIT values (p = 0.008) under low ALI levels, but the coefficient of the interaction was very small, representing a very limited effect. Iris shade and central corneal thickness values were not significantly associated with the LLIT. We also developed a censored linear model for ALI values ≤ 40 lux, showing a linear relationship between ALI and the LLIT, in which the LLIT value was 34.4 times greater than the ALI value.
  
  
  CONCLUSIONS
  Sclerotic scatter is more easily elicited under mesopic conditions than under photopic conditions and requires the LLIT value to be much higher than the ALI value, i.e. it requires extreme contrast.
authors.affiliation: Department of Ophthalmology, CHU de Caen, Caen Cedex 9, France.|Inserm, U 1075 COMETE, Caen Cedex 9, France.|Medical School, Unicaen, pôle de formation et de recherche en santé, Caen Cedex, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Denion
authors.affiliation: Department of Ophthalmology, CHU de Caen, Caen Cedex 9, France.|Medical School, Unicaen, pôle de formation et de recherche en santé, Caen Cedex, France.
authors.forename: Anne-Laure
authors.initials: AL
authors.lastname: Lux
authors.affiliation: Service d'ophtalmologie, CHU Rennes, Rennes, France.|Univ Rennes 1, Faculté de Médecine, Rennes, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Mouriaux
authors.affiliation: Médecine Interne et Maladies Infectieuses, CHU de Poitiers, Poitiers, France.|EA2694, Université Droit et Santé Lille 2, Lille, France.|Interuniversity Institute for Biostatistics and statistical Bioinformatics, Hasselt University, Hasselt, Belgium.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Béraud
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007498:Iris / Q000502:physiology*; D008029:Lighting; D008297:Male; D012590:Sclera / Q000502:physiology*