title: Characterisation of mitochondrial haplotypes occurred in a Candida albicans population.
abstract: The genetic background of mitochondrial DNA polymorphism in Candida albicans was studied by physical and functional mapping of four haplotypes identified recently in a hospital-population. The restriction patterns revealed considerable differences; however, the size of the mitochondrial DNA did not vary significantly. Sequence data demonstrated that size differences arose by short deletions, while restriction fragment length polymorphisms are caused by nucleotide substitutions in single sites. Gene rearrangement could not be detected; nevertheless, the coincidence of nucleotide substitution pattern in the inverted repeat region suggested the occurrence of homologue recombination.
authors.affiliation: Department of Microbiology, Faculty of Science and Informatics, University of Szeged , Szeged , Hungary.
authors.forename: Ilona
authors.initials: I
authors.lastname: Pfeiffer
authors.affiliation: Department of Microbiology, Faculty of Science and Informatics, University of Szeged , Szeged , Hungary.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Farkas
authors.affiliation: Department of Microbiology, Faculty of Science and Informatics, University of Szeged , Szeged , Hungary.
authors.forename: Judit
authors.initials: J
authors.lastname: Kucsera
authors.affiliation: Botany and Microbiology Department, King Saud University , Riyadh , Kingdom of Saudi Arabia.
authors.forename: Muthusamy
authors.initials: M
authors.lastname: Chandrasekaran
authors.affiliation: Botany and Microbiology Department, King Saud University , Riyadh , Kingdom of Saudi Arabia.
authors.forename: Shine
authors.initials: S
authors.lastname: Kadaikunnan
authors.affiliation: Botany and Microbiology Department, King Saud University , Riyadh , Kingdom of Saudi Arabia.
authors.forename: Naiyf S
authors.initials: NS
authors.lastname: Alharbi
authors.affiliation: Department of Microbiology, Faculty of Science and Informatics, University of Szeged , Szeged , Hungary.|Botany and Microbiology Department, King Saud University , Riyadh , Kingdom of Saudi Arabia.
authors.forename: Csaba
authors.initials: C
authors.lastname: Vágvölgyi
mesh_terms: D002176:Candida albicans / Q000235:genetics*; D004272:DNA, Mitochondrial; D006239:Haplotypes
chemical_list: D004272:DNA, Mitochondrial
keywords: Candida albicans; PCR; mitochondrial DNA; sequences