title: A catalogue of treatment and technologies for malignant pleural mesothelioma.
abstract: Malignant pleural mesothelioma is an aggressive fatal malignancy with a prognosis that has not significantly improved in the last decades. This review summarizes the current state of treatment and the various attempts that are made to improve overall survival for patients with malignant pleural mesothelioma. It also discusses technologies and protocols to test new and hopefully more effective compounds in a more individualized manner. These developments are expected to improve the prognosis for this group of patients.
authors.affiliation: a Division of Cell Biology II , The Netherlands Cancer Institute , Amsterdam , The Netherlands.
authors.forename: Laurel M
authors.initials: LM
authors.lastname: Schunselaar
authors.affiliation: b Thoraxoncology , The Netherlands Cancer Institute , Amsterdam , The Netherlands.
authors.forename: Josine M M F
authors.initials: JM
authors.lastname: Quispel-Janssen
authors.affiliation: a Division of Cell Biology II , The Netherlands Cancer Institute , Amsterdam , The Netherlands.
authors.forename: Jacques J C
authors.initials: JJ
authors.lastname: Neefjes
authors.affiliation: b Thoraxoncology , The Netherlands Cancer Institute , Amsterdam , The Netherlands.
authors.forename: Paul
authors.initials: P
authors.lastname: Baas
mesh_terms: D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D004195:Disease Models, Animal; D006801:Humans; D007167:Immunotherapy / Q000379:methods; D008175:Lung Neoplasms / Q000473:pathology / Q000628:therapy*; D008654:Mesothelioma / Q000473:pathology / Q000628:therapy*; D000086002:Mesothelioma, Malignant; D051379:Mice; D058990:Molecular Targeted Therapy / Q000379:methods; D050130:Oncolytic Virotherapy / Q000379:methods; D010997:Pleural Neoplasms / Q000473:pathology / Q000628:therapy*; D014407:Tumor Cells, Cultured
chemical_list: D020533:Angiogenesis Inhibitors
keywords: Chemotherapy; immunotherapy; mesothelioma; mouse models; pre-clinical models; primary tumor culture; targeted agent; treatment