title: Paroxysmal Perceptual Alteration: Drug-Induced Phenomenon or Schizophrenic Psychopathology?
abstract: Brief and repetitive episodes of perceptual changes, termed paroxysmal perceptual alteration (PPA), have been described in association with antipsychotic treatment. We report a case of paranoid schizophrenia who had such perceptual changes akin to PPA for 15 years, which was not related to antipsychotic treatment. There was a rapid resolution of PPA after treatment with low-dose clonazepam.
authors.affiliation: Department of Psychiatry, Kasturba Medical College, Manipal, India.
authors.forename: Samir Kumar
authors.initials: SK
authors.lastname: Praharaj
authors.forename: Sreejayan
authors.initials: S
authors.lastname: Kongasseri
authors.forename: Mahima
authors.initials: M
authors.lastname: Acharya
mesh_terms: D014150:Antipsychotic Agents / Q000009:adverse effects / Q000627:therapeutic use; D002998:Clonazepam / Q000627:therapeutic use*; D003024:Clozapine / Q000009:adverse effects / Q000627:therapeutic use; D018757:GABA Modulators / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010469:Perceptual Distortion / Q000187:drug effects*; D012563:Schizophrenia, Paranoid / Q000188:drug therapy* / Q000523:psychology*
chemical_list: D014150:Antipsychotic Agents; D018757:GABA Modulators; D002998:Clonazepam; D003024:Clozapine