title: Acute Hepatitis and Pneumonitis Caused by Disseminated Bacillus Calmette-Guérin Infection.
abstract: Intravesical instillation of Bacillus Calmette-Guérin (BCG) is the treatment of choice for superficial bladder carcinoma. We report a case of disseminated BCG infection in an early stage bladder cancer patient that initially presented with hepatitis followed by pneumonitis and sepsis. A complete clinical response was achieved in 14 days with anti-mycobacterial therapy and prednisolone. Disseminated BCG is a rare treatment complication and is likely a combination of direct infection and hypersensitivity.
authors.affiliation: Department of Radiation Oncology, King Hussein Cancer Center, Amman, Jordan.
authors.forename: Khaled
authors.initials: K
authors.lastname: Dibs
authors.affiliation: Department of Gastroenterology, King Hussein Cancer Center, Amman, Jordan.
authors.forename: Ihab
authors.initials: I
authors.lastname: Shehadeh
authors.affiliation: Infectious Disease Department, King Hussein Cancer Center, Amman, Jordan.
authors.forename: Osama
authors.initials: O
authors.lastname: Abu Atta