title: Intraocular pressure elevation after intravitreal triamcinolone acetonide injection: a Meta-analysis.
abstract: OBJECTIVE
  To report on intraocular pressure (IOP) after intravitreal injections of triamcinolone acetonide.
  
  
  METHODS
  Systematic literature review of studies that investigated the effects of an injection of triamcinolone intravitreal triamcinolone acetonide on IOP was conducted according to the Cochrane Collaboration methodology and the reported effects have been analyzed with Meta-analysis.
  
  
  RESULTS
  We found that the IOP follows an inverted-U shape pattern over time starting with an average value of 14.81±1.22 mm Hg before the injection, rising to a maximum of 19.48±2.15 mm Hg after one month of injection and falling down to 16.16±1.92 mm Hg after 6mo. Moreover, country of study, age, previous history of glaucoma and gender compositions matter for cross-study were different in reported IOP changes.
  
  
  CONCLUSIONS
  Our findings may be helpful in determining pressure elevation risk of intravitreal triamcinolone acetonide therapy as well as comparing it with those of more recent therapies such as the anti-vascular endothelial growth factor agents.
authors.affiliation: Department of Ophthalmology, Sariyer Ismail Akgun Public Hospital, Sariyer-Istanbul 34450, Turkey.
authors.forename: Cansu
authors.initials: C
authors.lastname: Yuksel-Elgin
authors.affiliation: Department of Economics, Bogazici University, Istanbul 34342, Turkey.
authors.forename: Ceyhun
authors.initials: C
authors.lastname: Elgin
keywords: Meta-analysis; intraocular pressure; intravitreal injections