title: The epidemiology of acne vulgaris in late adolescence.
abstract: OBJECTIVE
  Acne vulgaris is the most common skin condition affecting late adolescents across the globe. Although prior studies have evaluated epidemiologic patterns of acne vulgaris in various ethnicities and regions, adequate understanding of the worldwide burden of the disease associated with patients in their late adolescence (15-19-year olds) remains lacking.
  
  
  OBJECTIVE
  To assess the global burden of the disease associated with acne vulgaris for late adolescents (15-19-year olds) and provide an overview of the epidemiology, pathophysiology, and treatment options for acne in this population.
  
  
  METHODS
  Database summary study.
  
  
  METHODS
  Global Burden of Disease Study 2010 database.
  
  
  METHODS
  Global Burden of Disease regions comprised countries with prevalence of acne vulgaris between the ages of 15 and 19 years.
  
  
  METHODS
  Geographic region-level disability-adjusted life year rates (per 100,000 persons) associated with acne vulgaris in years 1990 through 2010. Median percentage change in disability-adjusted life year rates was estimated for each region across the specified study period.
  
  
  CONCLUSIONS
  Acne vulgaris-associated disease burden exhibits global distribution and has continued to grow in prevalence over time within this population. This continued growth suggests an unmet dermatologic need worldwide for this disorder and potential opportunities for improved access and delivery of dermatologic care. Our analysis of the literature reveals numerous opportunities for enhanced patient care. To that end, we highlight some of the effective and promising treatments currently available and address important factors, such as sex, nationality, genetics, pathophysiology, and diet, as they relate to acne vulgaris in late adolescence.
authors.affiliation: Department of Dermatology, University of Colorado School of Medicine, Aurora, CO, USA.
authors.forename: Darren D
authors.initials: DD
authors.lastname: Lynn
authors.affiliation: Department of Dermatology, University of Colorado School of Medicine, Aurora, CO, USA.
authors.forename: Tamara
authors.initials: T
authors.lastname: Umari
authors.affiliation: Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Dermatology Service, US Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, CO, USA.
authors.forename: Cory A
authors.initials: CA
authors.lastname: Dunnick
authors.affiliation: Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, CO, USA; Dermatology Service, US Department of Veterans Affairs, Eastern Colorado Health Care System, Denver, CO, USA; Department of Epidemiology, Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
authors.forename: Robert P
authors.initials: RP
authors.lastname: Dellavalle
keywords: GBD; diet; epidemiology; hormones; review