title: [Technical guidelines for the prevention, diagnosis and treatment of Zika virus infection].
abstract: Infection Zika virus is an emerging disease in the Americas region, which is caused by Zika virus (ZIKV), an arbovirus of the flavivirus genus. The ZIKV is transmitted by the bite of Aedes mosquitoes, both in urban and jungle area. After the mosquito bite, the disease symptoms usually appear after an incubation period of three to twelve days. The infection may be asymptomatic or presented with fever and not purulent conjunctivitis, headache, myalgia, arthralgia, asthenia, maculopapular rash, edema in lower limbs and, less frequently, retro-orbital pain, anorexia, vomiting, diarrhea or pain abdominal. Symptoms last for 4-7 days and are self-limiting. Neurological and autoimmune complications are rare. Since 2014 it has been detected native circulation of Zika virus in the Americas. So far, there is no specific antiviral treatment or effective vaccine, so it's giving priority symptomatic and supportive treatment for the acute phase and make an early diagnosis of atypical and severe forms.
authors.affiliation: Coordinación Técnica de Excelencia Clínica, Unidad de Atención Médica, Dirección de Prestaciones Médicas, Instituto Mexicano del Seguro Social, Ciudad de México, México. antonio.barrera@imss.gob.mx.
authors.forename: Antonio
authors.initials: A
authors.lastname: Barrera-Cruz
authors.forename: Rita Delia
authors.initials: RD
authors.lastname: Díaz-Ramos
authors.forename: Ana Belem
authors.initials: AB
authors.lastname: López-Morales
authors.forename: Concepción
authors.initials: C
authors.lastname: Grajales-Muñiz
authors.forename: Arturo
authors.initials: A
authors.lastname: Viniegra-Osorio
authors.forename: Jaime Antonio
authors.initials: JA
authors.lastname: Zaldívar-Cervera
authors.forename: José Jesús
authors.initials: JJ
authors.lastname: Arriaga-Dávila
mesh_terms: D000349:Africa / Q000453:epidemiology; D001208:Asia / Q000453:epidemiology; D002489:Central America / Q000453:epidemiology; D003131:Combined Modality Therapy; D003140:Communicable Disease Control / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D013020:South America / Q000453:epidemiology; D000071243:Zika Virus Infection / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy* / Q000635:transmission
keywords: Arbovirus infections; Arboviruses; Communicable disease control; Epidemiology; Virus diseases