title: Plasma exchange in Immunoglobulin A nephropathy with thrombotic microangiopathy and acute cortical necrosis.
abstract: A 25-year-old female presented with decreased urine output, deranged renal function, thrombocytopenia, and hemolytic anemia. Kidney biopsy was consistent with thrombotic microangiopathy with acute cortical necrosis and Immunoglobulin A nephropathy (IgAN). Hemolytic anemia, thrombocytopenia and urine output improved after five sessions of plasma exchange. Renal function showed a delayed recovery and serum creatinine normalized by 3 months. This is first case of successful use of plasma exchange in hemolytic uremic syndrome with cortical necrosis associated with IgAN.
authors.affiliation: Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: P
authors.initials: P
authors.lastname: Doddi
authors.affiliation: Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: K
authors.initials: K
authors.lastname: Gowda
authors.affiliation: Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: R
authors.initials: R
authors.lastname: Ramachandran
authors.affiliation: Department of Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: R
authors.initials: R
authors.lastname: Nada
authors.affiliation: Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: V
authors.initials: V
authors.lastname: Kumar
authors.affiliation: Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: M
authors.initials: M
authors.lastname: Rathi
authors.affiliation: Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: H S
authors.initials: HS
authors.lastname: Kohli
authors.affiliation: Department of Nephrology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: K L
authors.initials: KL
authors.lastname: Gupta
keywords: Hemolytic uremic syndrome; Immunoglobulin A nephropathy; thrombotic microangiopathy