title: Clinical and economic outcomes of Acinetobacter vis a vis non-Acinetobacter infections in an Indian teaching hospital.
abstract: BACKGROUND
  Acinetobacter infections are a major nosocomial infection causing epidemics of infection in the Intensive Care Units (ICU).
  
  
  OBJECTIVE
  This study estimates the clinical and economic outcomes of Acinetobacter infections and compares them with those of non-Acinetobacter bacterial infections.
  
  
  METHODS
  Prospective cross-sectional observational study carried out for 6 months in the medicine ICU of a tertiary care hospital.
  
  
  METHODS
  Patients were divided in two groups, one group with Acinetobacter infections and the other with non-Acinetobacter infections. The data was collected for infection, length of stay (LOS), mortality and cost along with patient demographics from the hospital records for analysis.
  
  
  METHODS
  The data was analyzed using Statistical Package for the Social Sciences Version 15.0. The LOS and cost of treatment (COT) for the two groups were compared using the nonparametric Mann-Whitney U-test.
  
  
  RESULTS
  A total of 220 patients were studied out of which 91 had Acinetobacter infections. The median LOS was 20 days in Group-A and 12 days in Group-B (P < 0.0001). The median COT was INR 125,862 in Group-A and INR 68,228 in the Group-B (P < 0.0001). Mortality in Group-A and Group-B was 32.97 and 32.56 (P = 0.949) respectively.
  
  
  CONCLUSIONS
  The burden of Acinetobacter infections in ICUs is increasing with the increase in LOS and COT for the patients. The infection control team has to play a major role in reducing the rate of nosocomial infections.
authors.affiliation: Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India.
authors.forename: Priyendu
authors.initials: P
authors.lastname: Asim
authors.affiliation: Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India.
authors.forename: Nagappa Anantha
authors.initials: NA
authors.lastname: Naik
authors.affiliation: Department of Medicine, Kasturba Medical College, Manipal, Karnataka, India.
authors.forename: Varma
authors.initials: V
authors.lastname: Muralidhar
authors.affiliation: Department of Microbiology, Kasturba Medical College, Manipal, Karnataka, India.
authors.forename: K Eshwara
authors.initials: KE
authors.lastname: Vandana
authors.affiliation: Department of Pharmacy Management, Manipal College of Pharmaceutical Sciences, Manipal, Karnataka, India.
authors.forename: A Prabhu
authors.initials: AP
authors.lastname: Varsha
keywords: Acinetobacter species; direct cost; length of stay; mortality