title: A Fluorescent Sensor for Dual-Channel Discrimination between Phosgene and a Nerve-Gas Mimic.
abstract: The ability to analyze highly toxic chemical warfare agents (CWAs) and related chemicals in a rapid and precise manner is essential in order to alleviate serious threats to humankind and public security caused by unexpected terrorist attacks and industrial accidents. In this investigation, we designed a o-phenylenediamine-pyronin linked dye that is capable of both fluorogenic and colorimetric discrimination between phosgene and the prototypical nerve-agent mimic, diethyl chlorophosphate (DCP) in the solution or gas phase. Moreover, this dye has been used to construct a portable kit that can be employed for real-time monitoring of DCP and phosgene in the field, both in a discriminatory manner, and in a simple and safe way.
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 120-750, Korea.|Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Yanbian University, Yanji, 133-002, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Yanbian University, Yanji, 133-002, China.
authors.forename: Yiying
authors.initials: Y
authors.lastname: Zeng
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 120-750, Korea.
authors.forename: Chen
authors.initials: C
authors.lastname: Liyan
authors.affiliation: Key Laboratory of Natural Resources of Changbai Mountain & Functional Molecules, Ministry of Education, Yanbian University, Yanji, 133-002, China. wuxue@ybu.edu.cn.
authors.forename: Xue
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Chemistry and Nano Science, Ewha Womans University, Seoul, 120-750, Korea. jyoon@ewha.ac.kr.
authors.forename: Juyoung
authors.initials: J
authors.lastname: Yoon
mesh_terms: D005456:Fluorescent Dyes / Q000737:chemistry*; D018716:Molecular Mimicry; D000067397:Nerve Agents / Q000737:chemistry*; D010705:Phosgene / Q000737:chemistry*; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D000067397:Nerve Agents; D010705:Phosgene
keywords: carbenes; fluorescence; nerve-gas mimics; phosgene; sensors