title: Asymptomatic bacteriuria among antenatal women in Lagos.
abstract: This cross-sectional study was undertaken to determine the prevalence of asymptomatic bacteriuria (ASB), the commonest bacterial isolates and the antibiotic sensitivity pattern among 556 pregnant women in Lagos University Teaching Hospital (LUTH), Nigeria. Women with a bacterial count over 100,000 colony-forming units per millilitre of the same organisms in paired urine samples were considered to have ASB. The prevalence of ASB was 14.6%. Klebsiella was the commonest micro-organism (39.2%) isolated. ASB was significantly associated with marital status, body mass index and parity. There was a significant relationship between urinary nitrites and ASB. The isolated organisms showed remarkable resistance to commonly prescribed antibiotics such as amoxicillin, cloxacillin and trimethoprim but good sensitivity to ofloxacin, gentamycin and ceftazidime. These facts have implications for the management of ASB in pregnancy.
authors.affiliation: a Department of Obstetrics and Gynaecology , College of Medicine and Lagos University Teaching Hospital , Lagos , Nigeria.
authors.forename: Joseph Ayodeji
authors.initials: JA
authors.lastname: Olamijulo
authors.affiliation: b Federal Institute of Industrial Research Staff Clinic , Lagos , Nigeria , and.
authors.forename: Chris Olu
authors.initials: CO
authors.lastname: Adewale
authors.affiliation: c Lagoon Hospitals , Lagos , Nigeria.
authors.forename: Olalekan
authors.initials: O
authors.lastname: Olaleye
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D058345:Asymptomatic Infections / Q000453:epidemiology*; D001437:Bacteriuria / Q000453:epidemiology* / Q000382:microbiology / Q000652:urine; D003430:Cross-Sectional Studies; D024881:Drug Resistance, Bacterial; D004756:Enterobacteriaceae Infections / Q000453:epidemiology / Q000382:microbiology / Q000652:urine; D005260:Female; D006801:Humans; D007709:Klebsiella / Q000187:drug effects / Q000302:isolation & purification; D008826:Microbial Sensitivity Tests; D009549:Nigeria / Q000453:epidemiology; D009573:Nitrites / Q000652:urine; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000382:microbiology / Q000652:urine; D015995:Prevalence; D014556:Urine / Q000737:chemistry / Q000382:microbiology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D009573:Nitrites
keywords: Bacteriuria; Escherichia coli; Klebsiella; nitrites; pregnancy; urinary tract infection