title: Dose-Response Relation Between Work Hours and Cardiovascular Disease Risk: Findings From the Panel Study of Income Dynamics.
abstract: OBJECTIVE
  The aim of this study was to examine the presence of a dose-response relationship between work hours and incident cardiovascular disease (CVD) in a representative sample of U.S. workers.
  
  
  METHODS
  A retrospective cohort study of 1926 individuals from the Panel Study of Income Dynamics (1986 to 2011) employed for at least 10 years. Restricted cubic spline regression was used to estimate the dose-response relationship of work hours with CVD.
  
  
  RESULTS
  A dose-response relationship was observed in which an average workweek of 46 hours or more for at least 10 years was associated with an increased risk of CVD. Compared with working 45 hours per week, working an additional 10 hours per week or more for at least 10 years increased CVD risk by at least 16%.
  
  
  CONCLUSIONS
  Working more than 45 work hours per week for at least 10 years may be an independent risk factor for CVD.
authors.affiliation: University of Texas Health Science Center, School of Public Health, Houston (Drs Conway, Pompeii); University of Texas Health Science Center, School of Public Health, San Antonio (Drs Roberts, Gimeno); and University of St. Thomas, Houston, Texas (Dr Follis).
authors.forename: Sadie H
authors.initials: SH
authors.lastname: Conway
authors.forename: Lisa A
authors.initials: LA
authors.lastname: Pompeii
authors.forename: Robert E
authors.initials: RE
authors.lastname: Roberts
authors.forename: Jack L
authors.initials: JL
authors.lastname: Follis
authors.forename: David
authors.initials: D
authors.lastname: Gimeno
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D016272:Occupational Health; D012189:Retrospective Studies; D013997:Time Factors; D014481:United States / Q000453:epidemiology; D014940:Work Schedule Tolerance; D055815:Young Adult