title: Potential Biomarkers in Diagnosis of Human Gastric Cancer.
abstract: The high incidence of gastric cancer (GC) and its consequent mortality rate severely threaten human's health. It is not frequently diagnosed until a relatively advanced stage. Surgery is the only potentially curative treatment. Thus, early screening and diagnosis are critical for patients with GC. The tumor marker assays used currently for detecting GC are simple and rapid, but the usage is limited by its low sensitivity and specificity. Here, we provide a brief description of some new potential markers and new biotechnological methods for the diagnosis of GC, hoping to find out more effective approaches for early detection of GC.
authors.affiliation: a College of Pharmaceutical Sciences, Southwest University , Chongqing , China.
authors.forename: Zhihao
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: a College of Pharmaceutical Sciences, Southwest University , Chongqing , China.
authors.forename: Mengmeng
authors.initials: M
authors.lastname: Dou
authors.affiliation: a College of Pharmaceutical Sciences, Southwest University , Chongqing , China.
authors.forename: Xiaofang
authors.initials: X
authors.lastname: Yao
authors.affiliation: a College of Pharmaceutical Sciences, Southwest University , Chongqing , China.
authors.forename: Hao
authors.initials: H
authors.lastname: Tang
authors.affiliation: a College of Pharmaceutical Sciences, Southwest University , Chongqing , China.
authors.forename: Zhubo
authors.initials: Z
authors.lastname: Li
authors.affiliation: a College of Pharmaceutical Sciences, Southwest University , Chongqing , China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zhao
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism*; D055088:Early Detection of Cancer; D018398:Homeodomain Proteins / Q000378:metabolism; D006801:Humans; D060492:Low Density Lipoprotein Receptor-Related Protein-5 / Q000378:metabolism; D035683:MicroRNAs / Q000097:blood; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000378:metabolism; D043562:Receptors, G-Protein-Coupled / Q000378:metabolism; D012680:Sensitivity and Specificity; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000378:metabolism*; D014157:Transcription Factors / Q000378:metabolism; D051840:Y-Box-Binding Protein 1 / Q000378:metabolism
chemical_list: D014408:Biomarkers, Tumor; D018398:Homeodomain Proteins; D060492:Low Density Lipoprotein Receptor-Related Protein-5; D035683:MicroRNAs; D018719:Erb-b2 Receptor Tyrosine Kinases; D043562:Receptors, G-Protein-Coupled; D014157:Transcription Factors; D051840:Y-Box-Binding Protein 1; C088334:Distal-less homeobox proteins; C116884:LGR5 protein, human; C555482:LRP5 protein, human; C070856:YBX1 protein, human; C508053:ERBB2 protein, human
keywords: Diagnosis; Gastric cancer; Tumor biomarker