title: Chemotherapy and pelvic radiotherapy-induced  bladder injury.
abstract: An understanding of the basics of the anatomy of the bladder mucosa is essential to better understand the pathophysiology of chemo-and radiotherapy-induced cystitis. Following an overview of bladder anatomy and the definitions and causes of bladder injury, the mechanisms of cyclophosphamide (CP)-induced bladder injury are discussed as a specific example.
authors.forename: Bülent
authors.initials: B
authors.lastname: Çetinel
mesh_terms: D018906:Antineoplastic Agents, Alkylating / Q000009:adverse effects*; D003520:Cyclophosphamide / Q000008:administration & dosage / Q000009:adverse effects*; D003556:Cystitis / Q000209:etiology*; D006801:Humans; D010388:Pelvis; D011832:Radiation Injuries / Q000209:etiology*; D011878:Radiotherapy / Q000009:adverse effects; D001743:Urinary Bladder / Q000187:drug effects* / Q000528:radiation effects*
chemical_list: D018906:Antineoplastic Agents, Alkylating; D003520:Cyclophosphamide