title: Asymmetric Brønsted Acid Catalyzed Substitution of Diaryl Methanols with Thiols and Alcohols for the Synthesis of Chiral Thioethers and Ethers.
abstract: An enantioselective addition of thiols and alcohols to aza-ortho-quinone methides, starting from diaryl methanols, was developed. The asymmetric additions occur under mild reaction conditions in the presence of chiral phosphoric acids and furnish the corresponding adducts with excellent yields and enantioselectivities.
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Adisak
authors.initials: A
authors.lastname: Chatupheeraphat
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Hsuan-Hung
authors.initials: HH
authors.lastname: Liao
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Steffen
authors.initials: S
authors.lastname: Mader
authors.affiliation: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Sako
authors.affiliation: The Institute of Scientific and Industrial Research (ISIR), Osaka University, Mihogaoka, Ibaraki-shi, Osaka, 567-0047, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Sasai
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany.
authors.forename: Iuliana
authors.initials: I
authors.lastname: Atodiresei
authors.affiliation: Institute of Organic Chemistry, RWTH Aachen University, Landoltweg 1, 52074, Aachen, Germany. magnus.rueping@rwth-aachen.de.|King Abdullah University of Science and Technology (KAUST), KAUST Catalysis Center (KCC), Thuwal, 23955-6900, Saudi Arabia. magnus.rueping@rwth-aachen.de.
authors.forename: Magnus
authors.initials: M
authors.lastname: Rueping
keywords: Brønsted acids; Michael addition; carbenium ions; ortho-quinone methides; substitution