title: The effects of resistance exercise training on arterial stiffness in metabolic syndrome.
abstract: OBJECTIVE
  Arterial stiffness is a strong independent risk factor for cardiovascular disease and is elevated in individuals with metabolic syndrome (MetS). Resistance training is a popular form of exercise that has beneficial effects on muscle mass, strength, balance and glucose control. However, it is unknown whether resistance exercise training (RT) can lower arterial stiffness in patients with MetS. Thus, the aim of this study was to examine whether a progressive RT program would improve arterial stiffness in MetS.
  
  
  METHODS
  A total of 57 subjects (28 healthy sedentary subjects; 29 MetS) were evaluated for arterial structure and function, including pulse wave velocity (cfPWV: arterial stiffness), before and after an 8-week period of RT or continuation of sedentary lifestyle.
  
  
  RESULTS
  We found that 8 weeks of progressive RT increased skeletal muscle strength in both Con and MetS, but did not change arterial stiffness in either MetS (cfPWV; Pre 7.9 ± 0.4 m/s vs. Post 7.7 ± 0.4 m/s) or healthy controls (cfPWV; Pre 6.9 ± 0.3 m/s vs. Post 7.0 ± 0.3 m/s). However, when cfPWV is considered as a continuous variable, high baseline measures of cfPWV tended to show a decrease in cfPWV following RT.
  
  
  CONCLUSIONS
  Eight weeks of progressive RT did not decrease the group mean values of arterial stiffness in individuals with MetS or healthy controls.
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.|Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: E
authors.initials: E
authors.lastname: DeVallance
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.|Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: S
authors.initials: S
authors.lastname: Fournier
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.|Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: K
authors.initials: K
authors.lastname: Lemaster
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: C
authors.initials: C
authors.lastname: Moore
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.|Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: S
authors.initials: S
authors.lastname: Asano
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: D
authors.initials: D
authors.lastname: Bonner
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: D
authors.initials: D
authors.lastname: Donley
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.|Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA.
authors.forename: I M
authors.initials: IM
authors.lastname: Olfert
authors.affiliation: Division of Exercise Physiology, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA. pchantler@hsc.wvu.edu.|Center for Cardiovascular and Respiratory Sciences, School of Medicine, West Virginia University, P.O. Box 9227, Morgantown, WV, 26506, USA. pchantler@hsc.wvu.edu.
authors.forename: P D
authors.initials: PD
authors.lastname: Chantler
mesh_terms: D001158:Arteries / Q000502:physiology*; D002318:Cardiovascular Diseases / Q000503:physiopathology; D015444:Exercise / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000503:physiopathology*; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D063177:Pulse Wave Analysis / Q000379:methods; D055070:Resistance Training / Q000379:methods; D012307:Risk Factors; D059289:Vascular Stiffness / Q000502:physiology*
keywords: Arterial stiffness; Central hemodynamics; Exercise; Metabolic syndrome