title: Safety of a picosecond laser with diffractive lens array (DLA) in the treatment of Fitzpatrick skin types IV to VI: A retrospective review.
abstract: BACKGROUND
  Laser therapy in patients with skin of color is associated with an increased rate of complications. The 755-nm picosecond laser with the diffractive lens array (DLA) has been used for the treatment of scars, striae, and rejuvenation. By delivering high energy to focused areas, the DLA minimizes complications.
  
  
  OBJECTIVE
  This study explores the adverse events associated with treatment with the 755-nm picosecond laser with DLA in individuals with Fitzpatrick skin type IV to VI.
  
  
  METHODS
  A retrospective chart review of patients treated with the 755-nm picosecond laser with DLA with a standardized spot size of 6 mm, fluence of 0.71 J/cm(2), and pulse width of 750 to 850 picoseconds was performed. Standard clinical photographs were obtained before treatment and at follow-up. Treatment sites were assessed for dyspigmentation, erythema, edema, and herpetic lesions.
  
  
  RESULTS
  A total of 56 patients with Fitzpatrick skin type IV to VI, atrophic and hypertrophic scars, and pigmented lesions or striae were included. Ten patients (17.9%) were lost to follow-up. Transient adverse events, most commonly erythema and hyperpigmentation, were reported after therapy; these resolved in all cases.
  
  
  CONCLUSIONS
  Retrospective design is a limitation.
  
  
  CONCLUSIONS
  The 755-nm picosecond laser with the DLA device may be a safe therapeutic alternative for unwanted scars, pigmented lesions, and striae in patients with skin of color.
authors.affiliation: Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York.
authors.forename: Adele
authors.initials: A
authors.lastname: Haimovic
authors.affiliation: Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York; Laser & Skin Surgery Center of New York, New York, New York.
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: Brauer
authors.affiliation: Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York; Laser & Skin Surgery Center of New York, New York, New York.
authors.forename: Yoon-Soo
authors.initials: YS
authors.lastname: Cindy Bae
authors.affiliation: Ronald O. Perelman Department of Dermatology, New York University Langone Medical Center, New York, New York; Laser & Skin Surgery Center of New York, New York, New York. Electronic address: Rgeronemus@laserskinsurgery.com.
authors.forename: Roy G
authors.initials: RG
authors.lastname: Geronemus
mesh_terms: D000152:Acne Vulgaris / Q000473:pathology / Q000532:radiotherapy*; D000328:Adult; D000368:Aged; D002921:Cicatrix / Q000473:pathology / Q000532:radiotherapy*; D015331:Cohort Studies; D004954:Esthetics; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D017495:Hyperpigmentation / Q000473:pathology / Q000532:radiotherapy*; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D061214:Patient Safety; D012189:Retrospective Studies; D012880:Skin Pigmentation; D016896:Treatment Outcome
keywords: cutaneous laser; diffractive lens array; picosecond laser; postinflammatory hyperpigmentation; safety; skin of color