title: Impact of Short and Moderate Rest Intervals on the Acute Immunometabolic Response to Exhaustive Strength Exercise: Part II.
abstract: The purpose of this study was to investigate the influence of short and moderate recovery intervals during heavy strength exercise on performance, inflammatory, and metabolic responses in recreational weightlifters. Eight healthy subjects (age = 24.6 ± 4.1 years) performed 2 randomized sequences with different rest intervals: short = 90% of 1RM and 30 seconds rest allowed between sets; moderate = 90% of 1RM and 90 seconds rest allowed between sets. All sequences of exercises were performed over 4 sets until movement failure in the squat and bench press exercises, respectively. Glucose, TNF-α, IL-6, IL-10, IL-10/TNF-α ratio, and nonester fatty acid concentrations were assessed at the baseline, immediately postexercise, post-15 and post-30 minutes. We observed a statistically significant decrease after 30 seconds on maximum number of repetitions (p = 0.003) and total weight lifted (p = 0.006) after the bench press, and there was a marginal decrease in the squat (p = 0.055). The glucose concentrations showed a significant increase post-15 minutes in the 30-second condition (pre-exercise = 86.1 ± 9.1, immediately = 85.3 ± 8.2, post-15 = 97.0 ± 9.0, post-30 = 87.1 ± 5.3 mg/dl; p = 0.015); on the other hand, IL-10 increased post-30 minutes in the 90-second condition (pre-exercise = 18.2 ± 12.7, immediately = 16.4 ± 10.7, post-15 = 16.8 ± 12.2, post-30 = 35.0 ± 13.1 pg/ml; p < 0.001). In addition, the 90-second condition showed anti-inflammatory effects (as indicated by IL-10/TNF-α ratio: pre-exercise = 1.08 ± 1.32, immediately = 1.23 ± 1.20, post-15 = 1.15 ± 1.14, post-30 = 2.48 ± 2.07; p = 0.020) compared with the 30-second condition (pre-exercise = 1.30 ± 2.04, immediately = 0.99 ± 1.27, post-15 = 1.23 ± 1.82, post-30 = 1.28 ± 1.28; p = 0.635). Thus, we concluded that a moderate interval of recovery (90 seconds) during heavy strength exercise allowed higher workload, IL-10 levels, and IL-10/TNF-α ratio in recreational weightlifters.
authors.affiliation: 1Exercise and Immunometabolism Research Group, Department of Physical Education, Univer. Estadual Paulista (UNESP), Presidente Prudente, SP, Brazil; and 2Department of Kinesiology, Recreation, and Sport Studies, Coastal Carolina University, Conway, South Carolina.
authors.forename: Jose
authors.initials: J
authors.lastname: Gerosa-Neto
authors.forename: Fabrício E
authors.initials: FE
authors.lastname: Rossi
authors.forename: Eduardo Z
authors.initials: EZ
authors.lastname: Campos
authors.forename: Barbara M M
authors.initials: BM
authors.lastname: Antunes
authors.forename: Jason M
authors.initials: JM
authors.lastname: Cholewa
authors.forename: Fabio S
authors.initials: FS
authors.lastname: Lira
mesh_terms: D015502:Absorptiometry, Photon; D000328:Adult; D001786:Blood Glucose; D015444:Exercise / Q000502:physiology*; D005230:Fatty Acids, Nonesterified / Q000097:blood; D005260:Female; D006801:Humans; D016753:Interleukin-10 / Q000097:blood; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D055070:Resistance Training / Q000379:methods*; D012146:Rest / Q000502:physiology*; D013997:Time Factors; D014409:Tumor Necrosis Factor-alpha / Q000097:blood; D014891:Weight Lifting / Q000502:physiology
chemical_list: D001786:Blood Glucose; D005230:Fatty Acids, Nonesterified; D015850:Interleukin-6; D014409:Tumor Necrosis Factor-alpha; D016753:Interleukin-10