title: Irreversible pulpitis and achieving profound anesthesia: Complexities and managements.
abstract: Dental pain management is one of the most critical aspects of modern dentistry. Irreversible pulpitis and further root canal therapy might cause an untolerated pain to the patients. The improvements in anesthetic agents and techniques were one of the advantages of studying nerve biology and stimulation. This article tried to overview of the nerve activities in inflammatory environments or induced pain. Furthermore, the proper advises, and supplementary techniques were reviewed for better pain management of irreversible pulpitis.
authors.affiliation: Department of Endodontics, Oral Health Research Center, School of Dentistry, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Jalil
authors.initials: J
authors.lastname: Modaresi
authors.affiliation: Dental Students Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Amin
authors.initials: A
authors.lastname: Davoudi
authors.affiliation: Department of Operative Dentistry, School of Dentistry, Shahid Sadoughi University Medical Sciences, Yazd, Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Badrian
authors.affiliation: Dental Students Research Center, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Roya
authors.initials: R
authors.lastname: Sabzian
keywords: Anesthesia; nerve; pain; pulpitis