title: Toxicity Studies.
abstract: Toxicity studies in the animal models are done to determine the dose level recommended for the treatment of disease as drug. This guideline enables the characterization of adverse effects following repeated daily inhalation exposure to a test. This chapter includes oral and dermal toxicity studies which are discussed as per OECD guidelines. Both acute and subacute toxicity studies are given special emphasis.
mesh_terms: D000279:Administration, Cutaneous; D000284:Administration, Oral; D000818:Animals; D065132:Bioprospecting / Q000379:methods*; D004305:Dose-Response Relationship, Drug; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D023421:Models, Animal; D064209:Phytochemicals / Q000302:isolation & purification / Q000633:toxicity*; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000633:toxicity*; D010946:Plants, Medicinal; D018570:Risk Assessment; D013997:Time Factors; D023382:Toxicity Tests, Acute / Q000379:methods*; D059551:Toxicity Tests, Subacute / Q000379:methods*
chemical_list: D064209:Phytochemicals; D010936:Plant Extracts