title: Carcinoma of buccal mucosa: A site specific clinical audit.
abstract: BACKGROUND
  Carcinoma of buccal mucosa is the most common cancer of the oral cavity in India. Treatment of oral cancer poses unique reconstructive challenges, owing to the dynamic architecture of the oral cavity. Despite current progress in various treatment modalities, over the past 50 years survival rates have not improved drastically. Although, philosophy on treatment of buccal mucosa carcinoma remains well-established, due to the relative paucity of reported data, retrospective reviews of institutional experiences are of prime importance. This study provides a detailed insight on this site specific cancer of the oral cavity in the Indian population.
  
  
  OBJECTIVE
  The aim of this study is to analyze our experience with the management of carcinoma of buccal mucosa; associated clinical presentation, outcomes and prognostic factors.
  
  
  METHODS
  A retrospective chart review was performed of all cases of primary buccal mucosa carcinoma treated surgically between years 2008 and 2012 in SDM Craniofacial Unit, Karnataka, India.
  
  
  METHODS
  All cases were analyzed based on patient characteristics, clinical presentation, surgical and adjuvant therapy rendered and treatment outcomes. A retrospective chart review was carried out using the hospital's data base for the same.
  
  
  METHODS
  Kaplan-Meier methods were used for analyzing disease free survival (DFS). Univariate analysis of prognostic factors was performed with log rank test.
  
  
  RESULTS
  The significant variables in univariate analysis were: Overall stage, T-stage (T1/T2 vs. T3/T4) and nodal status (N0 vs. N+). We found that staging, tumor size and nodal status were significant prognostic factors for DFS.
  
  
  CONCLUSIONS
  The strong influence of overall disease stage, tumor size, nodal status, final histopathological report and habits of tobacco/betel quid chewing, on prognosis; emphasizes the importance of early diagnosis and prevention of carcinoma of buccal mucosa in the Indian population.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Craniofacial Unit, SDM College of Dental Sciences and Hospital, Dharwad, Karnataka, India.
authors.forename: V
authors.initials: V
authors.lastname: Singhania
authors.forename: B V
authors.initials: BV
authors.lastname: Jayade
authors.forename: V
authors.initials: V
authors.lastname: Anehosur
authors.forename: K
authors.initials: K
authors.lastname: Gopalkrishnan
authors.forename: N
authors.initials: N
authors.lastname: Kumar
mesh_terms: D000328:Adult; D000368:Aged; D003133:Commission on Professional and Hospital Activities; D018572:Disease-Free Survival; D006801:Humans; D008297:Male; D008875:Middle Aged; D009061:Mouth Mucosa / Q000473:pathology*; D009062:Mouth Neoplasms / Q000175:diagnosis* / Q000473:pathology; D009367:Neoplasm Staging; D011379:Prognosis; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult