title: Anterior-Chamber Angle and Axial Length Measurements in Normal Chinese Children.
abstract: To establish the physiological distribution of anterior-chamber angle parameters and axial length (AL) in a randomly sampled cohort of Chinese children.
  
  
  
  This was a prospective, cross-sectional study on randomly sampled Chinese children ages 7 to 15 years. Complete ophthalmologic examination was carried out on all participants; anterior-segment parameters and ALs were measured using Fourier-domain optical coherence tomography and automated biometers. Associations between the age, the sex, the refractive error, the iris thickness, the AL, and anterior-chamber depth (ACD) and angle measurements were analyzed using multiple correlation and regression tests. The relationship between the AL and other factors was studied by a linear regression analysis. Only the right eye data were analyzed for statistical purpose.
  
  
  
  A total of 541 children were enrolled in this study. There were no differences in angle parameters between sexes (P>0.05), but boys had a longer AL (P<0.01). The AL increased logarithmically with age in children (P<0.01, R=0.5552, b=6.18). Although the magnitude of myopia also increased with AL, this association was less robust (P<0.05, R=0.0917, b=-0.88). A multiple regression test indicated that the age and the ACD were independently associated with the increase in angle width (b=0.37 to 0.50 and 0.51 to 0.60, respectively; P<0.001).
  
  
  
  All angle measurements increased with age and were positively correlated with the ACD in children 7 to 15 years of age. The AL increased logarithmically with age.
authors.affiliation: *Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University †Department of Preventative Ophthalmology, Shanghai Eye Hospital, Shanghai Eye Disease Prevention and Treatment Center, Shanghai, China ‡Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami, Miami, FL.
authors.forename: Peiyao
authors.initials: P
authors.lastname: Jin
authors.forename: Meili
authors.initials: M
authors.lastname: Li
authors.forename: Xiangui
authors.initials: X
authors.lastname: He
authors.forename: Lina
authors.initials: L
authors.lastname: Lu
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Zhu
authors.forename: Ta Chen
authors.initials: TC
authors.lastname: Chang
authors.forename: Haidong
authors.initials: H
authors.lastname: Zou
mesh_terms: D000293:Adolescent; D000367:Age Factors; D000867:Anterior Chamber / Q000033:anatomy & histology*; D044466:Asian People; D058452:Axial Length, Eye / Q000033:anatomy & histology*; D002648:Child; D002681:China; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D007498:Iris / Q000033:anatomy & histology; D008297:Male; D011446:Prospective Studies; D012030:Refractive Errors / Q000473:pathology; D012737:Sex Factors; D041623:Tomography, Optical Coherence