title: DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation.
abstract: Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion protein, for treatment of PIV type 3 pneumonia in two allogeneic hematopoietic SCT recipients with respiratory failure.
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: B
authors.initials: B
authors.lastname: Dhakal
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: A
authors.initials: A
authors.lastname: D'Souza
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: M
authors.initials: M
authors.lastname: Pasquini
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: W
authors.initials: W
authors.lastname: Saber
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: T S
authors.initials: TS
authors.lastname: Fenske
authors.affiliation: Ansun BioPharma, San Diego, CA 92121, USA.
authors.forename: R B
authors.initials: RB
authors.lastname: Moss
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: W R
authors.initials: WR
authors.lastname: Drobyski
authors.affiliation: Division of Hematology Oncology, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: P
authors.initials: P
authors.lastname: Hari
authors.affiliation: Division of Infectious Disease, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: M Z
authors.initials: MZ
authors.lastname: Abidi