title: Relationship between quality-of-life after 1-year follow-up and severity of traumatic brain injury assessed by computerized tomography.
abstract: This paper studies the relationship between computed tomography (CT) scan on admission, according to Marshall's tomographic classification, and quality-of-life (QoL) after 1 year in patients admitted to the Intensive Care Unit (ICU) with traumatic brain injury (TBI).
  
  
  
  This study used validated scales including the Glasgow Outcome Scale and the PAECC (Project for the Epidemiologic Analysis of Critical Care Patients) QoL questionnaire.
  
  
  
  We enrolled 531 patients. After 1 year, 171 patients (32.2%) had died (missing data = 6.6%). Good recovery was seen in 22.7% of the patients, while 20% presented moderate disability. The PAECC score after 1 year was 9.43 ± 8.72 points (high deterioration). Patients with diffuse injury I had a mean of 5.08 points vs 7.82 in those with diffuse injury II, 11.76 in those with diffuse injury III and 19.29 in those with diffuse injury IV (p < 0.001). Multivariate analysis found that QoL after 1 year was associated with CT Marshall classification, depth of coma, age, length of stay, spinal injury and tracheostomy.
  
  
  
  Patients with TBI had a high mortality rate 1 year after admission, deterioration in QoL and significant impairment of functional status, although more than 40% were normal or self-sufficient. QoL after 1 year was strongly related to cranial CT findings on admission.
authors.affiliation: a IBIMA, Intensive Care Unit , Hospital Regional Universitario , Málaga , Spain.
authors.forename: Miguel Angel
authors.initials: MA
authors.lastname: Prieto-Palomino
authors.affiliation: a IBIMA, Intensive Care Unit , Hospital Regional Universitario , Málaga , Spain.
authors.forename: Emilio
authors.initials: E
authors.lastname: Curiel-Balsera
authors.affiliation: a IBIMA, Intensive Care Unit , Hospital Regional Universitario , Málaga , Spain.
authors.forename: Maria Dolores
authors.initials: MD
authors.lastname: Arias-Verdú
authors.affiliation: b Intensive Care Unit , Hospital Comarcal de la Axarquia , Velez-Málaga, Málaga , Spain.
authors.forename: Monica Delange-Van
authors.initials: MD
authors.lastname: Der Kroft
authors.affiliation: a IBIMA, Intensive Care Unit , Hospital Regional Universitario , Málaga , Spain.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Muñoz-López
authors.affiliation: a IBIMA, Intensive Care Unit , Hospital Regional Universitario , Málaga , Spain.
authors.forename: Juan Francisco
authors.initials: JF
authors.lastname: Fernández-Ortega
authors.affiliation: a IBIMA, Intensive Care Unit , Hospital Regional Universitario , Málaga , Spain.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Quesada-García
authors.affiliation: c Escuela Andaluza de Salud Pública , Instituto de Investigación Biosanitaria de Granada (Granada.ibs) , CIBERESP, Madrid , Spain.
authors.forename: Emilio
authors.initials: E
authors.lastname: Sanchez-Cantalejo
authors.affiliation: d Intensive Care Unit , Hospital de la Serranía de Ronda , Málaga , Spain.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Rivera-Fernández
mesh_terms: D000328:Adult; D000070642:Brain Injuries, Traumatic / Q000000981:diagnostic imaging* / Q000401:mortality / Q000523:psychology*; D015331:Cohort Studies; D005260:Female; D023261:Glasgow Outcome Scale; D017052:Hospital Mortality; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D011795:Surveys and Questionnaires; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D055815:Young Adult
keywords: Neuroimaging; quality of life; radiology; traumatic brain injury