title: MR Imaging-Guided Partial Volume Correction of PET Data in PET/MR Imaging.
abstract: Partial volume effects are caused by the limited spatial resolution of the PET system. There is increasing evidence that partial volume correction (PVC) is necessary to guarantee quantitative accuracy in PET; however, there is reluctance to apply PVC routinely in clinical practice, partly because of uncertainty regarding the method of choice. To perform accurate PVC, it is necessary to introduce information from high-resolution anatomic images, such as MR imaging. All the methods rely on accurate coregistration between the anatomic image and the PET image. PET/MR imaging offers clear advantages for PVC and can help alleviate the image registration issues.
authors.affiliation: Institute of Nuclear Medicine, University College London, UCLH, Euston Road (T-5), London NW1 2BU, UK. Electronic address: k.erlandsson@ucl.ac.uk.
authors.forename: Kjell
authors.initials: K
authors.lastname: Erlandsson
authors.affiliation: Institute of Nuclear Medicine, University College London Hospital, UCLH, Euston Road (T-5), London NW1 2BU, UK.
authors.forename: John
authors.initials: J
authors.lastname: Dickson
authors.affiliation: Department of Computer Science, University College London, Gower Street, London WC1E 6BT, UK.
authors.forename: Simon
authors.initials: S
authors.lastname: Arridge
authors.affiliation: Centre for Medical Imaging, University College London, 250 Euston Road, London NW1 2PG, UK.
authors.forename: David
authors.initials: D
authors.lastname: Atkinson
authors.affiliation: Centre for Medical Imaging Computing, University College London, Gower Street, London WC1E 6BT, UK.
authors.forename: Sebastien
authors.initials: S
authors.lastname: Ourselin
authors.affiliation: Institute of Nuclear Medicine, University College London, UCLH, Euston Road (T-5), London NW1 2BU, UK; The Centre for Medical Radiation Physics, University of Wollongong, Northfields Avenue, Wollongong NSW 2522, Australia.
authors.forename: Brian F
authors.initials: BF
authors.lastname: Hutton
mesh_terms: D001927:Brain Diseases / Q000000981:diagnostic imaging; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging; D003326:Coronary Circulation; D006321:Heart / Q000000981:diagnostic imaging; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000592:standards; D064847:Multimodal Imaging / Q000379:methods* / Q000592:standards; D009369:Neoplasms / Q000000981:diagnostic imaging; D019047:Phantoms, Imaging; D049268:Positron-Emission Tomography / Q000379:methods* / Q000592:standards
keywords: PET/MR imaging; Partial volume correction; Partial volume effects; Quantification