title: Bile duct carcinoma associated with congenital biliary dilatation in a 16-year-old female: a case report and literature review.
abstract: We encountered a very rare case of bile duct carcinoma associated with congenital biliary dilatation (CBD) in a 16-year-old female who was admitted to our hospital because of right upper abdominal pain and vomiting. Abdominal computed tomography demonstrated a cystic dilatation of the common bile duct measuring 7 cm in diameter and two enhanced tumors 4 cm in diameter located in the inferior bile duct and middle bile duct. Magnetic resonance cholangiopancreatography clearly demonstrated a cystic dilatation of the extrahepatic bile duct (Todani's CBD classification: type 4-A). Endoscopic retrograde cholangiopancreatography also revealed two tumors. Biopsy results of one of the tumors confirmed adenocarcinoma. Excision of the perihilar bile duct and subtotal stomach-preserving pancreaticoduodenectomy with dissection of the major lymph nodes were performed. A postoperative histopathologic examination revealed a well-differentiated tubular adenocarcinoma, which remained within the mucosal layer, and no lymph node metastasis was found. The postoperative course was uneventful, and the patient was discharged 10 days after surgery and has remained disease-free for 21 months.
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. deehii@is.icc.u-tokai.ac.jp.
authors.forename: Hideki
authors.initials: H
authors.lastname: Izumi
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. naoki-y@poppy.ocn.ne.jp.
authors.forename: Naoki
authors.initials: N
authors.lastname: Yazawa
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. furufuru@is.icc.u-tokai.ac.jp.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Furukawa
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. yarmasuoka@yahoo.co.jp.
authors.forename: Yoshihito
authors.initials: Y
authors.lastname: Masuoka
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. m_r_arefriends@yahoo.co.jp.
authors.forename: Misuzu
authors.initials: M
authors.lastname: Yamada
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. tm_4amm1419@yahoo.co.jp.
authors.forename: Taro
authors.initials: T
authors.lastname: Mashiko
authors.affiliation: Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. y-kawa.26124@tokail-u.jp.
authors.forename: Yohei
authors.initials: Y
authors.lastname: Kawashima
authors.affiliation: Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. ma_ogawa@tokai-u.jp.
authors.forename: Masami
authors.initials: M
authors.lastname: Ogawa
authors.affiliation: Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. y711kawa@is.icc.u-tokai.ac.jp.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Kawaguchi
authors.affiliation: Department of Internal Medicine, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. tetsu-m@is.icc.u-tokai.ac.jp.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Mine
authors.affiliation: Department of Pathology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. khira@is.icc.u-tokai.ac.jp.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Hirabayashi
authors.affiliation: Department of Gastrointestinal Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. nakagori@tokai-u.jp.
authors.forename: Toshio
authors.initials: T
authors.lastname: Nakagohri
keywords: Bile duct carcinoma; Congenital biliary dilatation; Pancreaticobiliary maljunction; Pancreaticoduodenectomy