title: Fe-Promoted Chlorobenzylation of Terminal Alkynes through Benzylic C(sp(3))-H Bond Functionalization.
abstract: A chlorobenzylation of terminal alkynes through Fe(II)-promoted benzylic C(sp(3))-H bond functionalization in the presence of NCS as a chloride source was developed. Compared with previous methods to prepare polysubstituted alkenyl halides, the presented procedure provides an efficient alternative with high atom and step economy under mild conditions. The transformation was established to proceed through a single-electron transfer (SET) process with benzyl cations as key intermediates.
authors.affiliation: College of Chemistry and Material Chemistry, Sichuan Normal University , Sichuan 610066, China.
authors.forename: Jiang-Ling
authors.initials: JL
authors.lastname: Shi
authors.affiliation: Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University , Beijing 100871, China.
authors.forename: Ji-Cheng
authors.initials: JC
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Material Chemistry, Sichuan Normal University , Sichuan 610066, China.
authors.forename: Bi-Qin
authors.initials: BQ
authors.lastname: Wang
authors.affiliation: College of Chemistry and Material Chemistry, Sichuan Normal University , Sichuan 610066, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Hu
authors.affiliation: College of Chemistry and Material Chemistry, Sichuan Normal University , Sichuan 610066, China.
authors.forename: Ke-Qing
authors.initials: KQ
authors.lastname: Zhao
authors.affiliation: Beijing National Laboratory of Molecular Sciences (BNLMS) and Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry, Peking University , Beijing 100871, China.|State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences , Shanghai 200032, China.
authors.forename: Zhang-Jie
authors.initials: ZJ
authors.lastname: Shi