title: Self-assembly of palladium nanoparticles on functional TiO2 nanotubes for a nonenzymatic glucose sensor.
abstract: Polydiallyldimethylammonium chloride, PDDA, was used as a stabilizer and linker for functionalized TiO2 nanotubes (TiO2 NTs). Self-assembled process with palladium nanoparticles (NPs) was successfully synthesized and used for the oxidation of glucose on glassy carbon electrodes. Based on the voltammetric and amperometric results, Pd NPs efficiently catalyzed the oxidation of glucose at -0.05 V in the presence of 0.1 M NaCl and showed excellent resistance toward interference poisoning from such interfering species as ascorbic acid, uric acid and urea. To further increase sensitivity, the Pd NPs-PDDA-TiO2 NTs/GCE was electrochemically treated with H2SO4 and NaOH, the glucose oxidation current was magnified 2.5 times than that before pretreatments due to greatly enhancing the electron transport property of the sensor based on the increased defect sites and surface oxide species. In view of the physiological level of glucose, the wide linear concentration range of glucose (4×10(-7)-8×10(-4)M) with a detection limit of 8×10(-8)M (S/N=3) was obviously good enough for clinical application.
authors.affiliation: School of Science, Honghe University, Mengzi, Yunnan 661100, China; College of Chemistry, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China; Fujian Key Lab of Medical Instrument & Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Xianlan
authors.initials: X
authors.lastname: Chen
authors.affiliation: School of Science, Honghe University, Mengzi, Yunnan 661100, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.affiliation: School of Science, Honghe University, Mengzi, Yunnan 661100, China.
authors.forename: Guowei
authors.initials: G
authors.lastname: Zhang
authors.affiliation: College of Chemistry, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China; Fujian Key Lab of Medical Instrument & Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Keyu
authors.initials: K
authors.lastname: Hou
authors.affiliation: College of Chemistry, Qishan Campus, Fuzhou University, Fuzhou, Fujian 350108, China; Fujian Key Lab of Medical Instrument & Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China. Electronic address: hbpan@fzu.edu.cn.
authors.forename: Haibo
authors.initials: H
authors.lastname: Pan
authors.affiliation: Fujian Key Lab of Medical Instrument & Pharmaceutical Technology, Yishan Campus, Fuzhou University, Fuzhou, Fujian 350002, China.
authors.forename: Min
authors.initials: M
authors.lastname: Du
mesh_terms: D002384:Catalysis; D055664:Electrochemical Techniques; D005947:Glucose / Q000032:analysis*; D057230:Limit of Detection; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D008855:Microscopy, Electron, Scanning; D043942:Nanotubes / Q000737:chemistry*; D010084:Oxidation-Reduction; D010165:Palladium / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry*; D014961:X-Ray Diffraction
chemical_list: C009495:titanium dioxide; D010165:Palladium; D014025:Titanium; D005947:Glucose
keywords: Functionalized TiO(2) nanotubes; Nonenzymatic glucose sensor; PDDA; Palladium nanoparticles; Self-assembled process