title: The importance of margins in head and neck cancer.
abstract: An estimated 200,000 deaths each year worldwide are due to cancer of the head and neck, mostly mucosal squamous cell carcinoma and nonmelanoma skin cancer. The status of surgical margins is important for prognosis and need for adjuvant therapy. We will discuss how margin status impacts outcomes and therapy, and the conundrum of determining margin status.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Harry Michael
authors.initials: HM
authors.lastname: Baddour
authors.affiliation: Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Kelly R
authors.initials: KR
authors.lastname: Magliocca
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia.
authors.forename: Amy Y
authors.initials: AY
authors.lastname: Chen
mesh_terms: D002280:Basal Cell Carcinoma / Q000473:pathology / Q000601:surgery; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery* / Q000628:therapy; D017024:Chemotherapy, Adjuvant; D005629:Frozen Sections; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology / Q000517:prevention & control* / Q000601:surgery* / Q000628:therapy; D006801:Humans; D007432:Intraoperative Period; D020360:Neoadjuvant Therapy / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000517:prevention & control*; D018365:Neoplasm, Residual / Q000517:prevention & control; D011379:Prognosis; D018714:Radiotherapy, Adjuvant; D020545:Respiratory Mucosa / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000517:prevention & control / Q000601:surgery; D013514:Surgical Procedures, Operative / Q000592:standards*; D015996:Survival Rate
keywords: head and neck squamous cell carcinoma; nonmelanoma skin cancer of the head and neck; surgical margins in head and neck cancer