title: [Prognosis of symptomatic epilepsies in relation to their age of onset, monitored at a neuropediatric section of regional reference over a period of three years].
abstract: OBJECTIVE
  To analyze the factors involved in the prognosis of symptomatic epilepsies in relation to their age at onset, monitored at a neuropediatric section of regional reference over a period of three years.
  
  
  METHODS
  Children diagnosed with symptomatic epilepsy, supervised from January 1, 2008 to December 31, 2010, collecting epidemiological, clinical and developmental data.
  
  
  RESULTS
  Of the 4595 children attended during the period, the diagnosis of epilepsy was established at 605 (13.17%): 277 (45.79%) symptomatic epilepsies. Symptomatic etiology predomininates in epileptic patients that started below one year of age, 67.72%, and between 1-3 years, 61.39%. 37.54% of symptomatic epilepsy is refractory, 72.92% have cognitive impairment, 55.23% have motor impairment and 17.32% have autism spectrum disorder. The younger the patient, the higher the percentage of refractoriness and display of any neurological or associated development impact. Some etiologies have higher rates of refractoriness.
  
  
  CONCLUSIONS
  A useful classification would be etiological, with two groups: a large group with established etiology or very likely genetic syndromes and another with no established cause. The age of onset of epilepsy in each etiological group adds prognostic orientation. Prognosis of epilepsy is overshadowed by refractoriness and associated neurodevelopmental disorders, which are generally worse at an earlier onset and in certain etiologies.
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: Laura
authors.initials: L
authors.lastname: Ochoa-Gomez
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: Javier
authors.initials: J
authors.lastname: Lopez-Pison
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: Ruth
authors.initials: R
authors.lastname: Fernando-Martinez
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: Cristina
authors.initials: C
authors.lastname: Fuertes-Rodrigo
authors.affiliation: Hospital Clinico Universitario Lozano Blesa, 50009 Zaragoza, Espana.
authors.forename: Pilar
authors.initials: P
authors.lastname: Samper-Villagrasa
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: Lorena
authors.initials: L
authors.lastname: Monge-Galindo
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Peña-Segura
authors.affiliation: HUMS. Hospital Universitario Miguel Servet, 50009 Zaragoza, Espana.
authors.forename: M Concepción
authors.initials: MC
authors.lastname: García-Jiménez
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D011379:Prognosis; D012189:Retrospective Studies; D013997:Time Factors