title: Alcoholic ketoacidosis: a case report and review of the literature.
abstract: Alcoholic ketoacidosis (AKA) is a cause of severe metabolic acidosis usually occurring in malnourished patients with a history of recent alcoholic binge, often on a background of alcohol dependency. AKA can be fatal due to associated electrolyte abnormalities and subsequent development of cardiac arrhythmias. This is a diagnosis that is often delayed or missed, in patients who present with a severe lactic and ketoacidosis. Here we report the case of a 64-year-old female who presented with generalized abdominal pain, nausea and shortness of breath. Blood gas analysis showed significant acidaemia with a pH of 7.10, bicarbonate of 2.9 mmol/l, and lactate of 11.7 mmol/l. Serum ketones were raised at 5.5 mmol/l. The diagnosis of AKA was suspected, and subsequent aggressive fluid resuscitation, management and monitoring were instituted. Given the early recognition of AKA and appropriate multidisciplinary team management, our patient had a good outcome and was discharged home without any complication.
authors.affiliation: Department of Medicine , University of Cambridge , Cambridge , UK.
authors.forename: Nurulamin M
authors.initials: NM
authors.lastname: Noor
authors.affiliation: Department of Gastroenterology , West Suffolk Hospital , Bury St Edmunds , UK.
authors.forename: Krishna
authors.initials: K
authors.lastname: Basavaraju
authors.affiliation: Department of Gastroenterology , West Suffolk Hospital , Bury St Edmunds , UK.
authors.forename: Dan
authors.initials: D
authors.lastname: Sharpstone