title: Two-dimensional-strain echocardiography in intensive care unit patients: A prospective, observational study.
abstract: OBJECTIVE
  Two-dimensional-strain echocardiography (2D-strain) is a promising technique for the early detection of myocardial dysfunction. Our study was aimed to assess its feasibility in the intensive care unit (ICU). Our secondary goal was to determine if 2D-strain could predict the patient's outcome.
  
  
  METHODS
  Conventional echocardiography and 2D-strain were performed on 64 consecutive patients admitted to our ICU. Using 2D-strain, the longitudinal deformation of the left ventricle was assessed. Feasibility of 2D-strain, diagnosis performance, and 28-day mortality prediction were determined.
  
  
  RESULTS
  2D-strain measurements could be performed in 77% of our patients. All 2D-strain variables related to ventricular performance were significantly impaired in the patients who died compared with those who survived. Strain global medium was the only independent echocardiographic variable predictor of 28-day mortality rate (odds ratio 0.60; 95% confidence interval 0.43-0.80, p = 0.002).
  
  
  CONCLUSIONS
  2D-strain measurement is feasible in ICU patients, enabling identifying early left ventricle dysfunction. Strain global medium is an independent predictor of 28-day mortality. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44:368-374, 2016.
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Cyril
authors.initials: C
authors.lastname: Nafati
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Victor
authors.initials: V
authors.lastname: Lançon
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Valery
authors.initials: V
authors.lastname: Blasco
authors.affiliation: Service d'anesthésie et de réanimation, hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Zieleskiewicz
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Karim
authors.initials: K
authors.lastname: Harti
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Wiramus
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Kelway
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Reydellet
authors.affiliation: Service d'anesthésie et de réanimation, hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: François
authors.initials: F
authors.lastname: Antonini
authors.affiliation: Service d'anesthésie et de réanimation, hôpital La Timone, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Albanèse
authors.affiliation: Service d'anesthésie et de réanimation, hôpital Nord, Assistance Publique-Hôpitaux de Marseille, Aix Marseille Université, Marseille, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Leone
mesh_terms: D000328:Adult; D000368:Aged; D003422:Critical Care / Q000379:methods*; D016638:Critical Illness; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology*
keywords: critical care; echocardiography; mortality; myocardial dysfunction; strain