title: Effects of Cardiopulmonary Bypass on Mediastinal Drainage and the Use of Blood Products in the Intensive Care Unit in 60- to 80-Year-Old Patients Who Have Undergone Coronary Artery Bypass Grafting.
abstract: OBJECTIVE
  The present study consisted of patients who underwent on-pump coronary artery bypass grafting (CABG) and off-pump CABG and investigated effect of using cardiopulmonary bypass (CPB) on the amount of postoperative drainage and blood products, red blood cell (RBC), free frozen plasma (FFP) given in the intensive care unit in 60-80-year-old patients who underwent CABG.
  
  
  METHODS
  The present study comprises a total of 174 patients who have undergone coronary artery bypass graft (off-pump or on-pump CABG) surgery in our clinic in between 2012-2015 year.
  
  
  RESULTS
  It was observed that the amount of drainage in the first 24 postoperative hours was lower in the on-pump CABG group (Group 1) when compared to off-pump group (Group 2) (Group 1 vs . Group 2; 703.5±253.8 ml vs . 719.6±209.4 ml;P =0.716). However, the amount of drainage in the second 24 hours was statistically significantly lower in the off-pump CABG group (Group 1 vs . Group 2; 259.8±170.6 mlvs . 190.1±129.1 ml; P =0.016). With regard to the amount of overall drainage, no statistically significant difference was observed between the two groups. Group 1 needed RBC transfusion higher than Group 2 (Group 1 vs . Group 2; 2.2±1.3 bag vs . 1.2±0.9 bag;P <0.001).
  
  
  CONCLUSIONS
  We can say that CPB influences the amount of second 24-hour drainage which indexed body surface area. In addition, CPB decreases hct, hb, thrombocyte count in ICU arrived, after 24 hours in postoperative period. Reduced thrombocyte counting effect can be appeared after 48 hours in the postoperative period of CPB.
authors.affiliation: Konya Research and Medical Center, Başkent University, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Aygün
authors.affiliation: Konya Research and Medical Center, Başkent University, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Özülkü
authors.affiliation: Konya Research and Medical Center, Başkent University, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Günday
mesh_terms: D000368:Aged; D002315:Cardiopulmonary Bypass / Q000379:methods*; D001026:Coronary Artery Bypass; D047549:Coronary Artery Bypass, Off-Pump; D004322:Drainage / Q000706:statistics & numerical data*; D017707:Erythrocyte Transfusion; D005260:Female; D006400:Hematocrit; D006801:Humans; D007362:Intensive Care Units; D008297:Male; D008875:Middle Aged; D010949:Plasma; D011184:Postoperative Period; D012189:Retrospective Studies; D013997:Time Factors