title: Primary diffuse leptomeningeal gliomatosis as a rare cause of pain in cervical spine.
abstract: BACKGROUND
  Primary diffuse leptomeningeal gliomatosis (PDLG) is a very rare neuro-oncological disease, with only 90 cases of PDLG described in medical literature so far.
  
  
  METHODS
  We present a case report of a 56-years-old female patient, who was originally hospitalized due to cervical spine pain lasting several months. Despite complex diagnostics and treatment, the neurological state of the patient progressively deteriorated. Patient died 10 months after the first reported symptom. Postmortem pathological findings resulted in the diagnosis of PDLG.
  
  
  CONCLUSIONS
  Affection of the cervical spine in early stages of PDLG is rare and has been described in only six patients so far. PDLG is a fatal neuro-oncological disease and it must be kept in mind in the differential diagnosis of persistent back pain syndromes.
authors.affiliation: Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. sivakste@gmail.com.
authors.forename: Štefan
authors.initials: Š
authors.lastname: Sivák
authors.affiliation: Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. emakantorova@gmail.com.
authors.forename: Ema
authors.initials: E
authors.lastname: Kantorová
authors.affiliation: Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. egonkurca@gmail.com.
authors.forename: Egon
authors.initials: E
authors.lastname: Kurča
authors.affiliation: Department of Pathological Anatomy, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. marcinek@jfmed.uniba.sk.
authors.forename: Juraj
authors.initials: J
authors.lastname: Marcinek
authors.affiliation: Department of Pathological Anatomy, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. slavikpavol@centrum.sk.
authors.forename: Pavol
authors.initials: P
authors.lastname: Slávik
authors.affiliation: Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. michalik@unm.sk.
authors.forename: Jozef
authors.initials: J
authors.lastname: Michalik
authors.affiliation: Clinic of Neurology, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Kollárova 2, 03659, Martin, Slovak Republic. vnosal@gmail.com.
authors.forename: Vladimír
authors.initials: V
authors.lastname: Nosáľ
mesh_terms: D001706:Biopsy; D001933:Brain Stem / Q000473:pathology; D002531:Cerebellum / Q000473:pathology; D002574:Cervical Vertebrae / Q000473:pathology; D005260:Female; D005910:Glioma / Q000175:diagnosis*; D006801:Humans; D008279:Magnetic Resonance Imaging; D055756:Meningeal Carcinomatosis / Q000175:diagnosis*; D008875:Middle Aged; D010146:Pain / Q000175:diagnosis* / Q000209:etiology*; D049268:Positron-Emission Tomography