title: Pain-Related Suppression of Beta Oscillations Facilitates Voluntary Movement.
abstract: Increased beta oscillations over sensorimotor cortex are antikinetic. Motor- and pain-related processes separately suppress beta oscillations over sensorimotor cortex leading to the prediction that ongoing pain should facilitate movement. In the current study, we used a paradigm in which voluntary movements were executed during an ongoing pain-eliciting stimulus to test the hypothesis that a pain-related suppression of beta oscillations would facilitate the initiation of a subsequent voluntary movement. Using kinematic measures, electromyography, and high-density electroencephalography, we demonstrate that ongoing pain leads to shorter reaction times without affecting the kinematics or accuracy of movement. Reaction time was positively correlated with beta power prior to movement in contralateral premotor areas. Our findings corroborate the view that beta-band oscillations are antikinetic and provide new evidence that pain primes the motor system for action. Our observations provide the first evidence that a pain-related suppression of beta oscillations over contralateral premotor areas leads to shorter reaction times for voluntary movement.
authors.affiliation: Laboratory for Rehabilitation Neuroscience, Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
authors.forename: Gaurav
authors.initials: G
authors.lastname: Misra
authors.affiliation: Laboratory for Rehabilitation Neuroscience, Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
authors.forename: Edward
authors.initials: E
authors.lastname: Ofori
authors.affiliation: Laboratory for Rehabilitation Neuroscience, Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
authors.forename: Jae Woo
authors.initials: JW
authors.lastname: Chung
authors.affiliation: Laboratory for Rehabilitation Neuroscience, Department of Applied Physiology and Kinesiology, University of Florida, Gainesville, FL, USA.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Coombes
mesh_terms: D001696:Biomechanical Phenomena; D001931:Brain Mapping; D004569:Electroencephalography; D005260:Female; D006801:Humans; D008297:Male; D009044:Motor Cortex / Q000502:physiology*; D009068:Movement / Q000502:physiology*; D010146:Pain / Q000503:physiopathology*; D011930:Reaction Time / Q000502:physiology; D012815:Signal Processing, Computer-Assisted; D055815:Young Adult
keywords: EEG; movement; pain; premotor cortex; reaction time