title: [Cereal-dependent exercise-induced anaphylaxis].
abstract: Wheat-dependent exercise-induced anaphylaxis (WDEIA) is increasing. In vitro test such as omega-5-gliadin levels are useful in the diagnosis, while oral single blind challenge tests (OCT) with wheat plus exercise continuous being the gold standard diagnostic method. This paper reports the case of a 38-year-old woman, with several episodes of anaphylaxis after eating different foods and doing exercise after ingestion. An allergy study was performed with positive skin prick tests for wheat, barley and rye. Total IgE 238.0KU/L, positive specific IgE (>100KU/L) to wheat, barley and rye, and negative to rTri-a-19 omega-5 gliadin. OCT with bread and exercise was positive. In this case of wheat-dependent exerciseinduced anaphylaxis (WDEIA) with negative serum specific IgE to omega-5-gliadin, negative results with gamma, alpha, bheta y omega-gliadin doesn't exclude the diagnosis of WDEIA.
authors.affiliation: Servicio de Alergia, Hospital General Universitario Gregorio Marañón, Madrid, España. martaseoanerodriguez@gmail.com.
authors.forename: Marta
authors.initials: M
authors.lastname: Seoane-Rodríguez
authors.forename: María Elisa
authors.initials: ME
authors.lastname: Caralli
authors.forename: Cristina
authors.initials: C
authors.lastname: Morales-Cabeza
authors.forename: Sarah
authors.initials: S
authors.lastname: Micozzi
authors.forename: Manuel
authors.initials: M
authors.lastname: De Barrio-Fernández
authors.forename: Patricia
authors.initials: P
authors.lastname: Rojas Pérez-Ezquerra
mesh_terms: D000328:Adult; D000485:Allergens; D000707:Anaphylaxis / Q000209:etiology*; D052179:Antigens, Plant / Q000276:immunology; D002523:Edible Grain / Q000009:adverse effects* / Q000276:immunology; D015444:Exercise; D005260:Female; D005903:Gliadin / Q000276:immunology; D006801:Humans; D007073:Immunoglobulin E / Q000097:blood; D016037:Single-Blind Method; D012882:Skin Tests; D021182:Wheat Hypersensitivity / Q000150:complications* / Q000175:diagnosis / Q000276:immunology
chemical_list: D000485:Allergens; D052179:Antigens, Plant; C475180:omega-5 gliadin, wheat; D007073:Immunoglobulin E; D005903:Gliadin
keywords: anaphylaxis; cereal; exercise