title: CHOROIDAL THICKNESS IN PATIENTS WITH CENTRAL SEROUS CHORIORETINOPATHY: Assessment of Haller and Sattler Layers.
abstract: OBJECTIVE
  To investigate subfoveal choroidal thickness and subanalyze Haller and Sattler layers in eyes with central serous chorioretinopathy (CSC), uninvolved fellow eyes, and eyes of healthy controls using enhanced depth imaging optical coherence tomography.
  
  
  METHODS
  Ocular findings and clinical features of 31 eyes with CSC, 24 fellow eyes and eyes of 30 healthy controls were analyzed retrospectively from October, 2014 to March, 2015. Subfoveal choroidal thickness was measured using enhanced depth imaging optical coherence tomography, and the thicknesses of Haller and Sattler layers were analyzed.
  
  
  RESULTS
  Mean subfoveal choroidal thickness and mean thickness of Haller layer were significantly greater in CSC than in fellow eyes (P = 0.043 and P = 0.036, respectively) and in normal control eyes (P < 0.001 each), and those of fellow eyes in CSC patients were significantly thicker than those in normal control eyes (P = 0.018 and P = 0.017, respectively). The thickness of Sattler layer did not differ significantly among these groups (P = 0.519).
  
  
  CONCLUSIONS
  Subfoveal choroidal thickness and the thickness of Haller layer were increased not only in affected but also in uninvolved fellow eyes of CSC patients. Nonvascular smooth muscle cells of the choroid may play a role in the pathophysiology of CSC, in response to increased sympathetic tone.
authors.affiliation: Department of Ophthalmology, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Yoo-Ri
authors.initials: YR
authors.lastname: Chung
authors.forename: Jong Wan
authors.initials: JW
authors.lastname: Kim
authors.forename: Seung Woo
authors.initials: SW
authors.lastname: Kim
authors.forename: Kihwang
authors.initials: K
authors.lastname: Lee
mesh_terms: D000368:Aged; D002196:Capillaries / Q000000981:diagnostic imaging / Q000473:pathology; D056833:Central Serous Chorioretinopathy / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002829:Choroid / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology; D004396:Coloring Agents / Q000008:administration & dosage; D005260:Female; D005451:Fluorescein Angiography; D006801:Humans; D007208:Indocyanine Green / Q000008:administration & dosage; D008297:Male; D008875:Middle Aged; D009131:Muscle, Smooth, Vascular / Q000000981:diagnostic imaging / Q000473:pathology*; D015588:Observer Variation; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green