title: β-Cyclodextrin anchoring onto pericarpium granati-derived magnetic mesoporous carbon for selective capture of lopid in human serum and pharmaceutical wastewater samples.
abstract: Functionalized magnetic carbonaceous nanomaterials, which are important materials with many practical and research applications in biomedical, pharmaceutical and biological fields, have recently attracted much attention. In this study, a magnetic mesoporous carbon coated with β-cyclodextrin (MMC@β-CD) was synthesized for the first time from natural pericarpium granati (PG). The as-obtained MMC@β-CD has high surface areas (203 m(2)g(-1)), large pore volumes (0.16 cm(3)g(-1)), relatively broad mesoporous sizes (6.8 nm) and a high saturation magnetization of 26.2 emu g(-1), which is sufficient for magnetic separation by an external magnetic field. The MMC@β-CD was used as an innovative adsorbent for magnetic solid-phase extraction of lopid via host-guest interaction prior to spectrofluorometric analysis. The proposed method was successfully applied to analyze lopid in human serum and pharmaceutical wastewater samples with recoveries in the range of 85.0-103.5% for the spiked samples. Overall, this work not only provides an inexpensive and eco-friendly method to fabricate MMC@β-CD (or MMC) from PG, but also develops a highly selective approach for capture of lopid in biological samples and environmental substances.
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China; School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, China.
authors.forename: Rui-Lin
authors.initials: RL
authors.lastname: Liu
authors.affiliation: School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, China.
authors.forename: Zhi-Qi
authors.initials: ZQ
authors.lastname: Zhang
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Wang-Hui
authors.initials: WH
authors.lastname: Jing
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Zhi-Min
authors.initials: ZM
authors.lastname: Luo
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Rui-Miao
authors.initials: RM
authors.lastname: Chang
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Ai-Guo
authors.initials: AG
authors.lastname: Zeng
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Wei
authors.initials: W
authors.lastname: Du
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China.
authors.forename: Chun
authors.initials: C
authors.lastname: Chang
authors.affiliation: School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, PR China. Electronic address: fuqiang@mail.xjtu.edu.cn.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Fu
mesh_terms: D002244:Carbon / Q000737:chemistry*; D005470:Fluorometry; D015248:Gemfibrozil / Q000032:analysis / Q000097:blood* / Q000302:isolation & purification; D006801:Humans; D029561:Lythraceae / Q000378:metabolism; D008280:Magnetics; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D016062:Porosity; D052616:Solid Phase Extraction; D017550:Spectroscopy, Fourier Transform Infrared; D013499:Surface Properties; D013818:Thermogravimetry; D062065:Wastewater / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000032:analysis*; D014961:X-Ray Diffraction; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D002244:Carbon; D015248:Gemfibrozil; D062065:Wastewater; D014874:Water Pollutants, Chemical; D047392:beta-Cyclodextrins; C031215:betadex
keywords: Beta-cyclodextrin; Human serum; Lopid; Magnetic mesoporous carbon; Pericarpium granati; Pharmaceutical wastewaters