title: Angry macrophages patrol for fibrin.
abstract: In this issue of Blood, Motley et al have identified a novel and unexpected mechanism for clearance of extravascular fibrin that is accomplished by a specific proinflammatory macrophage population and is dependent upon active plasmin, yet independent of known fibrinogen receptors.
authors.affiliation: THE SCRIPPS RESEARCH INSTITUTE;
authors.forename: Lindsey A
authors.initials: LA
authors.lastname: Miles
authors.affiliation: UNIVERSITY OF CALIFORNIA SAN DIEGO; AND VETERANS ADMINISTRATION SAN DIEGO HEALTHCARE SYSTEM.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Parmer
mesh_terms: D000818:Animals; D004705:Endocytosis; D005337:Fibrin / Q000378:metabolism*; D008264:Macrophages / Q000378:metabolism*; D054390:Receptors, CCR2 / Q000378:metabolism*
chemical_list: D054390:Receptors, CCR2; D005337:Fibrin