title: Dermatomycosis in three central bearded dragons (Pogona vitticeps) associated with Nannizziopsis chlamydospora.
abstract: Chronic dermatomycosis was identified in 3 central bearded dragons (Pogona vitticeps), held as companion animals by the same owner. Clinical signs of dermatomycosis included subcutaneous masses as well as crusty, erosive, and ulcerative skin lesions. The facial region was affected in 2 of the 3 cases. Masses were surgically excised, and histology confirmed necrotizing and granulomatous inflammatory processes associated with fungal hyphae. Two of the bearded dragons were euthanized because of their deteriorating condition. In both cases, postmortem histology confirmed systemic fungal infections despite treatment of 1 animal with itraconazole. In the third bearded dragon, therapy with voriconazole at 10 mg/kg was initially effective, but mycotic lesions reappeared 15 months later. Nannizziopsis chlamydospora was identified by PCR and subsequent DNA sequencing in 2 of these cases.
authors.affiliation: Small Animal Internal Medicine, Department for Companion Animals and Horses (Schmidt-Ukaj) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Microbiology (Loncaric, Spergser) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Pathology and Forensic Veterinary Medicine (Richter) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaVeterinary Hospital (Tierklinik) Strebersdorf, Vienna, Austria (Hochleithner) silvana.schmidt-ukaj@vetmeduni.ac.at.
authors.forename: Silvana
authors.initials: S
authors.lastname: Schmidt-Ukaj
authors.affiliation: Small Animal Internal Medicine, Department for Companion Animals and Horses (Schmidt-Ukaj) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Microbiology (Loncaric, Spergser) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Pathology and Forensic Veterinary Medicine (Richter) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaVeterinary Hospital (Tierklinik) Strebersdorf, Vienna, Austria (Hochleithner).
authors.forename: Igor
authors.initials: I
authors.lastname: Loncaric
authors.affiliation: Small Animal Internal Medicine, Department for Companion Animals and Horses (Schmidt-Ukaj) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Microbiology (Loncaric, Spergser) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Pathology and Forensic Veterinary Medicine (Richter) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaVeterinary Hospital (Tierklinik) Strebersdorf, Vienna, Austria (Hochleithner).
authors.forename: Joachim
authors.initials: J
authors.lastname: Spergser
authors.affiliation: Small Animal Internal Medicine, Department for Companion Animals and Horses (Schmidt-Ukaj) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Microbiology (Loncaric, Spergser) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Pathology and Forensic Veterinary Medicine (Richter) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaVeterinary Hospital (Tierklinik) Strebersdorf, Vienna, Austria (Hochleithner).
authors.forename: Barbara
authors.initials: B
authors.lastname: Richter
authors.affiliation: Small Animal Internal Medicine, Department for Companion Animals and Horses (Schmidt-Ukaj) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Microbiology (Loncaric, Spergser) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaInstitute of Pathology and Forensic Veterinary Medicine (Richter) of the Department for Pathobiology, University of Veterinary Medicine Vienna, AustriaVeterinary Hospital (Tierklinik) Strebersdorf, Vienna, Austria (Hochleithner).
authors.forename: Manfred
authors.initials: M
authors.lastname: Hochleithner
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000627:therapeutic use; D002912:Chrysosporium / Q000302:isolation & purification*; D003881:Dermatomycoses / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D003937:Diagnosis, Differential; D037901:Euthanasia, Animal; D005260:Female; D017964:Itraconazole / Q000627:therapeutic use; D008116:Lizards; D008297:Male
chemical_list: D000935:Antifungal Agents; D017964:Itraconazole
keywords: Bearded dragons; Chrysosporium; Nannizziopsis chlamydospora; dermatitis; mycosis; reptiles