title: Hyperthermic intra-peritoneal chemotherapy and anticancer immune response.
abstract: Peritoneal carcinomatosis (PC) is a metastatic disease of primary tumors localized in the abdomen. Although this disease is considered a terminal condition, recent treatments combining surgery with heated intra-peritoneal chemotherapy (HIPEC) significantly increase patient survival. We have determined that the protective effect of HIPEC is partially linked to the induction of an efficient anticancer immune response.
authors.affiliation: Inserm, U1065; Centre Méditerranéen de Médecine Moléculaire (C3M); équipe "contrôle métabolique des morts cellulaires"; Nice, France; Université de Nice-Sophia-Antipolis; Faculté de Médecine; Nice, France; Centre Hospitalier Universitaire de Nice; Département d'Anesthésie Réanimation; Nice, France.
authors.forename: Barbara
authors.initials: B
authors.lastname: Zunino
authors.affiliation: Inserm, U1065; Centre Méditerranéen de Médecine Moléculaire (C3M); équipe "contrôle métabolique des morts cellulaires"; Nice, France; Université de Nice-Sophia-Antipolis; Faculté de Médecine; Nice, France; Centre Hospitalier Universitaire de Nice; Département d'Anesthésie Réanimation; Nice, France.
authors.forename: Jean-Ehrland
authors.initials: JE
authors.lastname: Ricci
keywords: DAMPs; HIPEC; HSP90; anticancer immune response; peritoneal carcinomatosis