title: [Crusted scabies: A review].
abstract: Crusted scabies is a rare and severe form of infestation by Sarcoptes scabies var. hominis. It is characterized by profuse hyperkeratosis containing over 4000 mites per gram of skin, with treatment being long and difficult. The condition is both direct and indirectly contagious. It has a central role in epidemic cycles of scabies, the incidence of which is on the rise in economically stable countries. Recent discoveries concerning the biology of mites, the pathophysiology of hyperkeratosis and the key role of IL-17 in this severe form open up new therapeutic perspectives.
authors.affiliation: Service de dermatologie, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France. Electronic address: jouret.guillaume@ethique-genetique.com.
authors.forename: G
authors.initials: G
authors.lastname: Jouret
authors.affiliation: Service d'accueil des urgences, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France.
authors.forename: R
authors.initials: R
authors.lastname: Bounemeur
authors.affiliation: Service d'anatomie et cytologie pathologique, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France.
authors.forename: A
authors.initials: A
authors.lastname: Presle
authors.affiliation: Service d'anatomie et cytologie pathologique, centre hospitalier de Troyes, 101, avenue Anatole-France, 10000 Troyes, France.
authors.forename: R
authors.initials: R
authors.lastname: Takin
mesh_terms: D056810:Acaricides / Q000494:pharmacology / Q000627:therapeutic use; D000818:Animals; D057210:Delayed Diagnosis; D006801:Humans; D020381:Interleukin-17 / Q000502:physiology; D007559:Ivermectin / Q000494:pharmacology / Q000627:therapeutic use; D012520:Sarcoptes scabiei / Q000187:drug effects / Q000502:physiology; D012532:Scabies / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology / Q000503:physiopathology; D012720:Severity of Illness Index; D015163:Superinfection
chemical_list: D056810:Acaricides; D020381:Interleukin-17; D007559:Ivermectin
keywords: Crusted scabies; Gale croûteuse; Gale hyperkératosique; Gale norvégienne; IL-17; Sarcoptes scabiei var. hominis