title: [Place of indocyanine green coupled with fluorescence imaging in research of breast cancer sentinel node].
abstract: The sentinel node has a fundamental role in the management of early breast cancer. Currently, the double detection of blue and radioisotope is recommended. But in common practice, many centers use a single method. However, with a single detection, the risk of false negatives and the identification failure rate increase to a significant extent and the number of sentinel lymph node detected and removed is not enough. Furthermore, the tracers used until now show inconveniences. The purpose of this work is to present a new method of detection, using the green of indocyanine coupled with fluorescence imaging, and to compare it with the already existing methods. The method combined by fluorescence and isotopic is reliable, sure, of fast learning and could constitute a good strategy of detection. The major interest is to obtain a satisfactory number of sentinel nodes. The profit could be even more important for overweight patients. The fluorescence used alone is at the moment not possible. Wide ranging studies are necessary. The FLUOTECH, randomized study of 100 patients, comparing the isotopic method of double isotope technique and fluorescence, is underway to confirm these data.
authors.affiliation: CHU de Saint-Étienne, hôpital Nord, département d'obstétrique et gynécologie, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Vermersch
authors.affiliation: CHU de Saint-Étienne, hôpital Nord, département d'obstétrique et gynécologie, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France; Université Jean-Monnet, groupe de recherche sur la thrombose, EA 3065, 42000 Saint-Étienne, France.
authors.forename: Tiphaine
authors.initials: T
authors.lastname: Raia Barjat
authors.affiliation: CHU de Saint-Étienne, hôpital Nord, département d'obstétrique et gynécologie, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France.
authors.forename: Marianne
authors.initials: M
authors.lastname: Perrot
authors.affiliation: CHU de Saint-Étienne, hôpital Nord, département d'obstétrique et gynécologie, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France.
authors.forename: Suzanne
authors.initials: S
authors.lastname: Lima
authors.affiliation: CHU de Saint-Étienne, hôpital Nord, département d'obstétrique et gynécologie, avenue Albert-Raimond, 42270 Saint-Priest-en-Jarez, France; Université Jean-Monnet, groupe de recherche sur la thrombose, EA 3065, 42000 Saint-Étienne, France. Electronic address: celine.chauleur@chu-st-etienne.fr.
authors.forename: Céline
authors.initials: C
authors.lastname: Chauleur
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D004396:Coloring Agents / Q000008:administration & dosage; D005188:False Negative Reactions; D005260:Female; D005453:Fluorescence; D006801:Humans; D007208:Indocyanine Green / Q000008:administration & dosage; D059032:Learning Curve; D008198:Lymph Nodes / Q000473:pathology*; D021701:Sentinel Lymph Node Biopsy / Q000379:methods
chemical_list: D004396:Coloring Agents; D007208:Indocyanine Green
keywords: Breast cancer; Cancer du sein; Fluorescence; Ganglion sentinelle; Indocyanine green; Sentinel node; Vert d’indocyanine