title: [IMPACT OF A HEIGHTENED INTRAABDOMINAL PRESSURE ON POLYORGAN INSUFFICIENCY OCCURRENCE IN AN ACUTE PANCREATITIS].
abstract: In experiment the impact of intraabdominal hypertension (IAH) on an acute pancreatitis (AP) course was studied up. The procedure of an acute experiment, using intraparenchymatose introduction of 40% solution of ethanol, was proposed. The isolated influence of IAH on target organs was investigated, as well as its impact on the simulated severe AP course. Morphological changes in pancreas, small intestine, kidneys, liver in an AP were studied up. While performing the investigation a negative impact of IAH in AP was noted, such as the polyorgan insufficiency occurence.
authors.forename: I V
authors.initials: IV
authors.lastname: Khomyak
authors.forename: Yu O
authors.initials: YO
authors.lastname: Furmanov
authors.forename: I M
authors.initials: IM
authors.lastname: Savytska
authors.forename: O V
authors.initials: OV
authors.lastname: Kit
authors.forename: A I
authors.initials: AI
authors.lastname: Khomyak
mesh_terms: D000208:Acute Disease; D000818:Animals; D021461:Animals, Outbred Strains; D004195:Disease Models, Animal; D000431:Ethanol; D006651:Histocytochemistry; D007421:Intestine, Small / Q000473:pathology; D059325:Intra-Abdominal Hypertension / Q000139:chemically induced / Q000473:pathology*; D007668:Kidney / Q000473:pathology; D008099:Liver / Q000473:pathology; D009102:Multiple Organ Failure / Q000175:diagnosis / Q000473:pathology*; D010179:Pancreas / Q000473:pathology; D010195:Pancreatitis / Q000139:chemically induced / Q000473:pathology*; D011312:Pressure; D051381:Rats
chemical_list: D000431:Ethanol