title: Severe Thrombotic Complication of Eltrombopag in a Cirrhotic Patient.
abstract: We present a patient with hepatitis C virus (HCV) and cirrhosis who was treated with eltrombopag for idiopathic thrombocytopenic purpura and was incidentally found to have a right atrial thrombus with extension into the left internal jugular vein. Eltrombopag was discontinued and the patient was treated with thrombectomy and anticoagulation. Given the proposed use of eltrombopag in HCV-associated thrombocytopenia, we advise caution when treating cirrhotics who are at higher intrinsic risk of thrombosis.
authors.affiliation: Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA.
authors.forename: Alexandra J
authors.initials: AJ
authors.lastname: Baumann
authors.affiliation: Department of Internal Medicine, Albert Einstein Medical Center, Philadelphia, PA.
authors.forename: David S
authors.initials: DS
authors.lastname: Wheeler
authors.affiliation: Division of Hematology and Oncology, Albert Einstein Medical Center, Philadelphia, PA.
authors.forename: Gabor
authors.initials: G
authors.lastname: Varadi
authors.affiliation: Division of Hepatology, Albert Einstein Medical Center, Philadelphia, PA.
authors.forename: Eyob
authors.initials: E
authors.lastname: Feyssa