title: Recent Developments in Pediatric Community-Acquired Pneumonia.
abstract: Community-acquired pneumonia (CAP) is the most common acute infectious cause of death in children worldwide. Consequently, research into the epidemiology, diagnosis, treatment, and prevention of pediatric CAP spans the translational research spectrum. Herein, we aim to review the most significant findings reported by investigators focused on pediatric CAP research that has been reported in 2014 and 2015. Our review focuses on several key areas relevant to the clinical management of CAP. First, we will review recent advances in the understanding of CAP epidemiology worldwide, including the role of vaccination in the prevention of pediatric CAP. We also report on the expanding role of existing and emerging diagnostic technologies in CAP classification and management, as well as advances in optimizing antimicrobial use. Finally, we will review CAP management from the policy and future endeavors standpoint, including the influence of clinical practice guidelines on clinician management and patient outcomes, and future potential research directions that are in the early stages of investigation.
authors.affiliation: Division of Infectious Diseases, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO, 64108, USA. rmcculloh@cmh.edu.|Pediatrics and Internal Medicine, University of Missouri-Kansas City, Kansas City, MO, USA. rmcculloh@cmh.edu.
authors.forename: Russell J
authors.initials: RJ
authors.lastname: McCulloh
authors.affiliation: Division of Infectious Diseases, Children's Mercy Hospital, 2401 Gillham Road, Kansas City, MO, 64108, USA.
authors.forename: Karisma
authors.initials: K
authors.lastname: Patel
keywords: Community-acquired pneumonia; Molecular diagnostics; Pediatric; Pneumococcus; Viral pneumonia