title: Clinical Characteristics of and Preventative Strategies for Peripartum Group A Streptococcal Infections.
abstract: OBJECTIVE
  To describe clinical characteristics in parturients with group A streptococcal infection and suggest preventive strategies.
  
  
  METHODS
  We performed a retrospective review of all group A streptococci cultures from women presenting with peripartum fever or abdominal tenderness between January 2008 and May 2015 in a university hospital. Records and epidemiologic investigations of patients and staff were reviewed.
  
  
  RESULTS
  Thirty-seven patients with group A streptococci cultures were identified, with an incidence of one identified postpartum group A streptococcal infection per 2,837 deliveries. Eighty-nine percent of infections occurred postpartum with isolates obtained mainly from the genital tract. Symptoms for group A streptococcal puerperal sepsis were high fever and abdominal tenderness, mostly appearing within 48 hours postpartum. More than one fifth of patients (n=7) developed streptococcal toxic shock syndrome often complicated by multiorgan failure, hysterectomy, and hospitalization in the intensive care unit. There were no uniform risk factors before infection. Epidemiologic investigations suggested that only 23% of infections were nosocomially acquired and that 77% were community-acquired.
  
  
  CONCLUSIONS
  The high morbidity and the scarcity of distinct risk factors related to parturient group A streptococcal infections in the face of often community-acquired group A streptococci call for reassessing preventive strategies. These may include improved microbiological screening during pregnancy in high-prevalence areas or clinical and microbiological risk stratification in the immediate prepartum and peripartum period.
authors.affiliation: Lis Maternity Hospital, Department of Obstetrics and Gynecology, the Infectious Disease Unit, and the Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv University, Tel Aviv, and the Faculty of Nursing, Yezreel Valley College, Yezreel Valley, Israel.
authors.forename: Shiri
authors.initials: S
authors.lastname: Shinar
authors.forename: Yuval
authors.initials: Y
authors.lastname: Fouks
authors.forename: Sharon
authors.initials: S
authors.lastname: Amit
authors.forename: David
authors.initials: D
authors.lastname: Pauzner
authors.forename: Jalal
authors.initials: J
authors.lastname: Tarabeia
authors.forename: Vered
authors.initials: V
authors.lastname: Schechner
authors.forename: Ariel
authors.initials: A
authors.lastname: Many
mesh_terms: D005260:Female; D006801:Humans; D007557:Israel / Q000453:epidemiology; D011247:Pregnancy; D012189:Retrospective Studies; D013290:Streptococcal Infections / Q000453:epidemiology* / Q000517:prevention & control; D013297:Streptococcus pyogenes