title: Dioxins, DL-PCB and NDL-PCB accumulation profiles in livers from sheep and cattle reared in North-western Italy.
abstract: Products of animal origin represent the main route of human exposure to dioxins and dioxin-like PCBs (DL-compounds). Recently, concerns have been raised about ovine products, particularly the liver, in which relatively high levels of DL-compounds have been reported. We surveyed ovine and bovine livers in areas with no known sources of dioxin or DL-PCB contamination, in order to assess accumulation patterns for both DL-compounds and non-DL (NDL-) PCBs. None of the ovine and bovine samples exceeded the current Maximum Limits (MLs) for DL-compounds. Liver DL-compound TEQ concentrations were up to 5-fold higher in sheep than in cows. No statistically significant differences in total NDL-PCBs levels were found. The main contributors to TEQ levels were the Penta- and Hexa-chlorinated PCDFs and PCB 126. The results confirm the increased bioaccumulation in ovine liver towards specific DL-compounds even in ewes reared in areas with no known sources of PCDD/Fs or DL-PCBs contamination.
authors.affiliation: Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e valle D'Aosta, Torino, Italy. Electronic address: alessandro.benedetto@izsto.it.
authors.forename: A
authors.initials: A
authors.lastname: Benedetto
authors.affiliation: Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e valle D'Aosta, Torino, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Brizio
authors.affiliation: Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e valle D'Aosta, Torino, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Guaraldo
authors.affiliation: Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e valle D'Aosta, Torino, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Stella
authors.affiliation: Dipartimento Provinciale di Torino Arpa Piemonte, Grugliasco, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Cappa
authors.affiliation: Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e valle D'Aosta, Torino, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Baioni
authors.affiliation: Department of Veterinary Sciences, University of Torino, Grugliasco, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Spalenza
authors.affiliation: Department of Veterinary Sciences, University of Torino, Grugliasco, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Nebbia
authors.affiliation: Istituto Zooprofilattico Sperimentale del Piemonte, Liguria e valle D'Aosta, Torino, Italy.
authors.forename: M C
authors.initials: MC
authors.lastname: Abete
mesh_terms: D000818:Animals; D001572:Benzofurans / Q000032:analysis* / Q000378:metabolism; D002417:Cattle / Q000254:growth & development / Q000378:metabolism*; D000072338:Dibenzofurans, Polychlorinated; D005260:Female; D006801:Humans; D007558:Italy; D008099:Liver / Q000737:chemistry* / Q000378:metabolism; D011078:Polychlorinated Biphenyls / Q000032:analysis* / Q000378:metabolism; D000072317:Polychlorinated Dibenzodioxins / Q000032:analysis* / Q000378:metabolism; D012756:Sheep / Q000254:growth & development / Q000378:metabolism*; D013045:Species Specificity
chemical_list: D001572:Benzofurans; D000072338:Dibenzofurans, Polychlorinated; D000072317:Polychlorinated Dibenzodioxins; D011078:Polychlorinated Biphenyls; C023035:3,4,5,3',4'-pentachlorobiphenyl
keywords: Dioxin-like PCBs; Dioxins; cows; ewes; liver; marker PCBs