title: Synthesis and antimicrobial evaluation of some novel sulfonylamido-benzoxazoles.
abstract: A series of 2-(p-substituted phenyl)-5-[(4-substituted phenyl) sulfonylamido]-benzoxazoles were synthesized and tested for their antimicrobial activities. The structures of the new derivatives were elucidated by spectral techniques. The minimum inhibitory concentrations (MIC) of the new benzoxazoles were determined against standard bacterial and fungal strains and drug-resistant isolates and compared to those of several reference drugs.
authors.affiliation: Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara University , 06100, Tandogan, Ankara , Turkey.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Temiz-Arpaci
authors.affiliation: Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara University , 06100, Tandogan, Ankara , Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Doğanc
authors.affiliation: Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara University , 06100, Tandogan, Ankara , Turkey.
authors.forename: Duygu
authors.initials: D
authors.lastname: Sac
authors.affiliation: Faculty of Pharmacy, Department of Pharmaceutical Chemistry, Ankara University , 06100, Tandogan, Ankara , Turkey.
authors.forename: Elmas
authors.initials: E
authors.lastname: Sari
authors.affiliation: Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Trakya University , 22030, Edirne , Turkey.
authors.forename: Fatma
authors.initials: F
authors.lastname: Kaynak-Onurdag
authors.affiliation: Faculty of Pharmacy, Department of Pharmaceutical Microbiology, Trakya University , 22030, Edirne , Turkey.
authors.forename: Suzan
authors.initials: S
authors.lastname: Okten
mesh_terms: D000890:Anti-Infective Agents / Q000138:chemical synthesis*; D001583:Benzoxazoles / Q000138:chemical synthesis*
chemical_list: D000890:Anti-Infective Agents; D001583:Benzoxazoles
keywords: Benzoxazole; antibacterial activity; antifungal activity; sulfonylamides; synthesis