title: Sweet Relief: Reprogramming Gastric Endocrine Cells to Make Insulin.
abstract: Two promising approaches toward a cell-based cure for diabetes are the directed differentiation of pluripotent stem cells or lineage reprogramming of other cell types to generate beta cells. In this issue of Cell Stem Cell, Ariyachet et al. (2016) reprogrammed gastric endocrine cells to generate a renewable source of insulin-producing cells.
authors.affiliation: Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.
authors.forename: Heather A
authors.initials: HA
authors.lastname: McCauley
authors.affiliation: Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA; Division of Endocrinology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH 45229, USA. Electronic address: james.wells@cchmc.org.
authors.forename: James M
authors.initials: JM
authors.lastname: Wells
mesh_terms: D002454:Cell Differentiation; D065150:Cellular Reprogramming; D006801:Humans; D007328:Insulin / Q000378:metabolism*; D050417:Insulin-Secreting Cells / Q000166:cytology; D039904:Pluripotent Stem Cells / Q000166:cytology
chemical_list: D007328:Insulin