title: Aspterpenacids A and B, Two Sesterterpenoids from a Mangrove Endophytic Fungus Aspergillus terreus H010.
abstract: Two new sesterterpenoids, aspterpenacids A (1) and B (2), with an unusual carbon skeleton of a 5/3/7/6/5 ring system were isolated from the mangrove endophytic fungus Aspergillus terreus H010. Their structures were elucidated on the basis of spectroscopic methods, single-crystal X-ray diffraction analysis, and electronic circular dichroism calculations. A biogenetic pathway for 1 and 2 is proposed. Both 1 and 2 showed no significant antibacterial activity or cytotoxicity at 50 μM.
authors.forename: Zhaoming
authors.initials: Z
authors.lastname: Liu
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.forename: Senhua
authors.initials: S
authors.lastname: Chen
authors.forename: Yayue
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Key Laboratory of Functional Molecules from Oceanic Microorganism, Department of Education of Guangdong Province, Sun Yat-Sen University , Guangzhou 510080, China.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Lu
authors.forename: Dongni
authors.initials: D
authors.lastname: Chen
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Lin
authors.forename: Xishan
authors.initials: X
authors.lastname: Huang
authors.affiliation: Key Laboratory of Functional Molecules from Oceanic Microorganism, Department of Education of Guangdong Province, Sun Yat-Sen University , Guangzhou 510080, China.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: She
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D001230:Aspergillus / Q000737:chemistry*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D043982:Rhizophoraceae / Q000382:microbiology*; D054830:Sesterterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D054830:Sesterterpenes; C000609757:aspterpenacid A; C000609758:aspterpenacid B