title: Aerobic Training after Myocardial Infarction: Remodeling Evaluated by Cardiac Magnetic Resonance.
abstract: BACKGROUND
  Numerous studies show the benefits of exercise training after myocardial infarction (MI). Nevertheless, the effects on function and remodeling are still controversial.
  
  
  OBJECTIVE
  To evaluate, in patients after (MI), the effects of aerobic exercise of moderate intensity on ventricular remodeling by cardiac magnetic resonance imaging (CMR).
  
  
  METHODS
  26 male patients, 52.9 ± 7.9 years, after a first MI, were assigned to groups: trained group (TG), 18; and control group (CG), 8. The TG performed supervised aerobic exercise on treadmill twice a week, and unsupervised sessions on 2 additional days per week, for at least 3 months. Laboratory tests, anthropometric measurements, resting heart rate (HR), exercise test, and CMR were conducted at baseline and follow-up.
  
  
  RESULTS
  The TG showed a 10.8% reduction in fasting blood glucose (p = 0.01), and a 7.3-bpm reduction in resting HR in both sitting and supine positions (p < 0.0001). There was an increase in oxygen uptake only in the TG (35.4 ± 8.1 to 49.1 ± 9.6 mL/kg/min, p < 0.0001). There was a statistically significant decrease in the TG left ventricular mass (LVmass) (128.7 ± 38.9 to 117.2 ± 27.2 g, p = 0.0032). There were no statistically significant changes in the values of left ventricular end-diastolic volume (LVEDV) and ejection fraction in the groups. The LVmass/EDV ratio demonstrated a statistically significant positive remodeling in the TG (p = 0.015).
  
  
  CONCLUSIONS
  Aerobic exercise of moderate intensity improved physical capacity and other cardiovascular variables. A positive remodeling was identified in the TG, where a left ventricular diastolic dimension increase was associated with LVmass reduction.
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Nataly Lino
authors.initials: NL
authors.lastname: Izeli
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Aurélia Juliana Dos
authors.initials: AJ
authors.lastname: Santos
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Júlio César
authors.initials: JC
authors.lastname: Crescêncio
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Ana Clara Campagnolo Real
authors.initials: AC
authors.lastname: Gonçalves
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Valéria
authors.initials: V
authors.lastname: Papa
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Fabiana
authors.initials: F
authors.lastname: Marques
authors.affiliation: Divisão de Emergência, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Antônio
authors.initials: A
authors.lastname: Pazin-Filho
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: Lourenço
authors.initials: L
authors.lastname: Gallo-Júnior
authors.affiliation: Hospital das Clínicas, Faculdade de Medicina de Ribeirão Preto, USP, Ribeirão Preto, SP, Brazil.
authors.forename: André
authors.initials: A
authors.lastname: Schmidt
mesh_terms: D000328:Adult; D015992:Body Mass Index; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D015444:Exercise / Q000502:physiology*; D005080:Exercise Test; D005081:Exercise Therapy / Q000379:methods*; D006339:Heart Rate / Q000502:physiology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000534:rehabilitation*; D012016:Reference Values; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D013318:Stroke Volume / Q000502:physiology; D013997:Time Factors; D016896:Treatment Outcome; D014280:Triglycerides / Q000097:blood; D016277:Ventricular Function, Left / Q000502:physiology; D020257:Ventricular Remodeling / Q000502:physiology*
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides