title: Abnormal Nocturnal Behavior due to Hypoglycemia in a Patient with Type 2 Diabetes.
abstract: Abnormal nocturnal behavior can have many causes, including primary sleep disorder, nocturnal seizures, and underlying medical or neurological disorders. A 79-year-old woman with type 2 diabetes was admitted for evaluation of abnormal nocturnal behavior. Every night at around 04:30 she was observed displaying abnormal behavior including leg shaking, fumbling with bedclothes, crawling around the room with her eyes closed, and non-responsiveness to verbal communication. Polysomnography with 20-channel electroencephalography (EEG) was performed. EEG showed that the posterior dominant rhythm was slower than that observed in the initial EEG, with diffuse theta and delta activities intermixed, and no epileptiform activity. The serum glucose level was 35 mg/dL at that time, and both the EEG findings and clinical symptoms were resolved after an intravenous injection of 50 mL of 50% glucose. These results indicate that nocturnal hypoglycemia should be considered as one of the possible etiologies in patients presenting with abnormal nocturnal behavior.
authors.affiliation: Sleep Disorders Center, Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hosptial, Cheonan, Korea.
authors.forename: Kwang Ik
authors.initials: KI
authors.lastname: Yang
authors.affiliation: Department of Clinical Pharmacology, Soonchunhyang University College of Medicine, Cheonan, Korea.
authors.forename: Hyung Ki
authors.initials: HK
authors.lastname: Kim
authors.affiliation: Sleep Disorders Center, Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hosptial, Cheonan, Korea.
authors.forename: Jeehun
authors.initials: J
authors.lastname: Baek
authors.affiliation: Sleep Disorders Center, Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hosptial, Cheonan, Korea.
authors.forename: Doh-Eui
authors.initials: DE
authors.lastname: Kim
authors.affiliation: Sleep Disorders Center, Department of Neurology, Soonchunhyang University College of Medicine, Cheonan Hosptial, Cheonan, Korea.
authors.forename: Hyung Kook
authors.initials: HK
authors.lastname: Park
mesh_terms: D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D004569:Electroencephalography; D005260:Female; D005947:Glucose / Q000627:therapeutic use; D006801:Humans; D007003:Hypoglycemia / Q000150:complications* / Q000188:drug therapy; D017286:Polysomnography; D012893:Sleep Wake Disorders / Q000209:etiology*
chemical_list: D005947:Glucose
keywords: abnormal nocturnal behavior; hypoglycemia