title: Sympathetic Nervous System, Hypertension, Obesity and Metabolic Syndrome.
abstract: Experimental and clinical studies have clearly shown the role of the sympathetic nervous system in the pathophysiology of several cardiovascular and non-cardiovascular diseases. This short review will be aimed at focusing and discussing the new information collected on two specific clinical conditions such as obesity and metabolic syndrome. The paper will briefly describe the four main mechanisms that represent the common link between these two pathophysiological conditions and that through the sympathetic nervous system contribute to increase the cardiovascular risk.
authors.affiliation: Cardiology Department, S. Luca Hospital, Istituto Auxologico Italiano, Piazza Brescia 20, 20149, Milan, Italy. g_seravalle@yahoo.com.
authors.forename: Gino
authors.initials: G
authors.lastname: Seravalle
authors.affiliation: Clinica Medica, University Milano Bicocca, Monza, Italy.|IRCCS Multimedica, Sesto San Giovanni, Milan, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Grassi
mesh_terms: D000818:Animals; D017704:Baroreflex; D015415:Biomarkers / Q000097:blood; D001794:Blood Pressure; D002319:Cardiovascular System / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D020738:Leptin / Q000097:blood; D024821:Metabolic Syndrome / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D056128:Obesity, Abdominal / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D018384:Oxidative Stress; D011379:Prognosis; D012084:Renin-Angiotensin System; D012307:Risk Factors; D013564:Sympathetic Nervous System / Q000503:physiopathology*
chemical_list: D015415:Biomarkers; D007328:Insulin; D020738:Leptin
keywords: Baroreflex; Insulin resistance; Leptin; Metabolic syndrome; Obesity; Sympathetic nervous system