title: The influence of masked hypertension on the right ventricle: is everything really masked?
abstract: We sought to investigate right ventricular (RV) structure, function, and mechanics in subjects with masked hypertension (MH), normotensive, and sustained hypertensive patients. This cross-sectional study included 186 untreated subjects who underwent 24-hour ambulatory blood pressure (BP) monitoring and complete two-dimensional echocardiographic (2DE) examination including multilayer strain analysis. MH was diagnosed if clinic BP was normal (<140/90 mm Hg) and 24-hour BP was increased (≥130/80 mm Hg). Global and free-wall RV longitudinal strains were significantly lower in MH and sustained hypertensive patients comparing with controls. Systolic and early diastolic RV strain rates were lower, whereas late diastolic strain rate was higher, among patients with MH and sustained hypertension than in control group. Endocardial and midmyocardial RV strains were also significantly lower in MH and hypertensive patients. There was no difference between MH and subjects with sustained hypertension. RV structure, function, and deformation are significantly changed in subjects with MH and sustained hypertension.
authors.affiliation: Cardiology Department, University Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", Belgrade, Serbia; School of Medicine, Belgrade University, Belgrade, Serbia. Electronic address: marijana_tadic@hotmail.com.
authors.forename: Marijana
authors.initials: M
authors.lastname: Tadic
authors.affiliation: Clinical Research Unit, University of Milan-Bicocca and Istituto Auxologico Italiano, Meda, Italy.
authors.forename: Cesare
authors.initials: C
authors.lastname: Cuspidi
authors.affiliation: Cardiology Department, University Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", Belgrade, Serbia.
authors.forename: Vladan
authors.initials: V
authors.lastname: Vukomanovic
authors.affiliation: Cardiology Department, University Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", Belgrade, Serbia; School of Medicine, Belgrade University, Belgrade, Serbia.
authors.forename: Vera
authors.initials: V
authors.lastname: Celic
authors.affiliation: Cardiology Department, University Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", Belgrade, Serbia.
authors.forename: Tatjana
authors.initials: T
authors.lastname: Pavlovic
authors.affiliation: Cardiology Department, University Clinical Hospital Center "Dr. Dragisa Misovic-Dedinje", Belgrade, Serbia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Kocijancic
mesh_terms: D000368:Aged; D018660:Blood Pressure Monitoring, Ambulatory; D003430:Cross-Sectional Studies; D003971:Diastole; D004452:Echocardiography; D004699:Endocardium / Q000503:physiopathology; D005260:Female; D006325:Heart Atria / Q000000981:diagnostic imaging / Q000503:physiopathology; D006801:Humans; D008297:Male; D059468:Masked Hypertension / Q000150:complications* / Q000503:physiopathology; D008875:Middle Aged; D013599:Systole; D018497:Ventricular Dysfunction, Right / Q000209:etiology / Q000473:pathology / Q000503:physiopathology
keywords: Masked hypertension; right ventricle; two-dimensional speckle tracking