title: Facile synthesis of substituted 3-aminofurans through a tandem reaction of N-sulfonyl-1,2,3-triazoles with propargyl alcohols.
abstract: A relay catalysis strategy for substituted 3-aminofurans synthesis has been developed. This transformation involves a tandem reaction sequence through aza-vinyl-rhodium(ii) carbene O-H bond insertion, thermal propargyl-Claisen rearrangement and gold(i)-catalyzed intramolecular cyclization. More importantly, the current strategy employs simple feedstocks as starting materials, providing substituted 3-aminofurans in a highly efficient manner.
authors.affiliation: College of Chemistry and Chemical Engineering, Fujian Normal University, Fuzhou, Fujian 350007, P. R. China. jxchen@fjnu.edu.cn.
authors.forename: Xing
authors.initials: X
authors.lastname: Cheng
authors.forename: Yinghua
authors.initials: Y
authors.lastname: Yu
authors.forename: Zhifeng
authors.initials: Z
authors.lastname: Mao
authors.forename: Jianxin
authors.initials: J
authors.lastname: Chen
authors.forename: Xueliang
authors.initials: X
authors.lastname: Huang
mesh_terms: D000480:Alkynes / Q000737:chemistry*; D003500:Cyclization; D005663:Furans / Q000138:chemical synthesis* / Q000737:chemistry; D020005:Propanols / Q000737:chemistry*; D014230:Triazoles / Q000737:chemistry*
chemical_list: D000480:Alkynes; D005663:Furans; D020005:Propanols; D014230:Triazoles; C028255:propargyl alcohol