title: The Nurture of Tumors Can Drive Their Metabolic Phenotype.
abstract: Many commonly accepted principles in tumor metabolism rely on in vitro studies performed under conditions which cannot faithfully recapitulate tumor heterogeneity. Davidson et al. (2016), in this issue of Cell Metabolism, and Hensley et al. (2016) find that the in vivo environment dictates the metabolic phenotype of lung tumors in patients and mouse models.
authors.affiliation: Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Zachary T
authors.initials: ZT
authors.lastname: Schug
authors.affiliation: Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK.
authors.forename: Johan
authors.initials: J
authors.lastname: Vande Voorde
authors.affiliation: Cancer Metabolism Research Unit, Cancer Research UK Beatson Institute, Switchback Road, Glasgow G61 1BD, UK. Electronic address: e.gottlieb@beatson.gla.ac.uk.
authors.forename: Eyal
authors.initials: E
authors.lastname: Gottlieb