title: Plasmodium vivax Malaria Presenting with Multifocal Hemorrhagic Brain Infarcts in a School-going Child.
abstract: Cerebral malaria is a well-known complication of Plasmodium falciparum malaria. Over recent years, however, Plasmodium vivax also has been reported to cause cerebral malaria with or without co-infection with P. falciparum Here, we report a boy aged 10 years presenting with acute febrile encephalopathy with raised intracranial pressure to the emergency, who was later diagnosed to have P. vivax malaria. His neurological status improved gradually during 6 weeks of pediatric intensive care unit stay. We report this case to highlight the unusual radiologic findings in the patient, such as multifocal hemorrhagic infarcts in the brainstem, bilateral thalami, frontal cortex and basal ganglia, which have not been reported with P. vivax malaria.
authors.affiliation: Department of Pediatrics, AIIMS, 110029 New Delhi, India.
authors.forename: Santosh Kumar
authors.initials: SK
authors.lastname: Rathia
authors.affiliation: Department of Pediatrics, AIIMS, 110029 New Delhi, India.
authors.forename: Jhuma
authors.initials: J
authors.lastname: Sankar
authors.affiliation: Department of Radiology, AIIMS, 110029 New Delhi, India.
authors.forename: Devasenathipathy
authors.initials: D
authors.lastname: Kandasamy
authors.affiliation: Department of Pediatrics, AIIMS, 110029 New Delhi, India rlodha1661@gmail.com.
authors.forename: Rakesh
authors.initials: R
authors.lastname: Lodha
mesh_terms: D000071072:Acute Febrile Encephalopathy; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000962:Antimalarials / Q000008:administration & dosage / Q000627:therapeutic use; D037621:Artemisinins / Q000008:administration & dosage / Q000627:therapeutic use; D000077332:Artesunate; D001921:Brain / Q000000981:diagnostic imaging* / Q000469:parasitology; D002648:Child; D002981:Clindamycin / Q000008:administration & dosage / Q000627:therapeutic use; D004569:Electroencephalography; D006801:Humans; D015278:Intensive Care Units, Pediatric; D007427:Intracranial Pressure; D016779:Malaria, Cerebral / Q000188:drug therapy / Q000382:microbiology*; D016780:Malaria, Vivax / Q000175:diagnosis* / Q000188:drug therapy; D008297:Male; D010966:Plasmodium vivax / Q000302:isolation & purification*; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000962:Antimalarials; D037621:Artemisinins; D002981:Clindamycin; D000077332:Artesunate