title: Integrated metabolomics and phytochemical genomics approaches for studies on rice.
abstract: Metabolomics is widely employed to monitor the cellular metabolic state and assess the quality of plant-derived foodstuffs because it can be used to manage datasets that include a wide range of metabolites in their analytical samples. In this review, we discuss metabolomics research on rice in order to elucidate the overall regulation of the metabolism as it is related to the growth and mechanisms of adaptation to genetic modifications and environmental stresses such as fungal infections, submergence, and oxidative stress. We also focus on phytochemical genomics studies based on a combination of metabolomics and quantitative trait locus (QTL) mapping techniques. In addition to starch, rice produces many metabolites that also serve as nutrients for human consumers. The outcomes of recent phytochemical genomics studies of diverse natural rice resources suggest there is potential for using further effective breeding strategies to improve the quality of ingredients in rice grains.
authors.affiliation: RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045 Japan ; Kihara Institute for Biological Research, Yokohama City University, 641-12 Maioka-cho, Totsuka-ku, Yokohama, Kanagawa 244-0813 Japan.
authors.forename: Yozo
authors.initials: Y
authors.lastname: Okazaki
authors.affiliation: RIKEN Center for Sustainable Resource Science, 1-7-22 Suehiro-cho, Tsurumi-ku, Yokohama 230-0045 Japan ; Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo-ku, Chiba 260-8675 Japan.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Saito
mesh_terms: D002874:Chromosome Mapping; D023281:Genomics / Q000379:methods*; D006358:Hot Temperature; D006801:Humans; D055442:Metabolome / Q000235:genetics; D055432:Metabolomics / Q000379:methods*; D012275:Oryza / Q000235:genetics* / Q000378:metabolism* / Q000382:microbiology; D064209:Phytochemicals / Q000378:metabolism*; D000069600:Plant Breeding / Q000379:methods; D040641:Quantitative Trait Loci / Q000235:genetics
chemical_list: D064209:Phytochemicals
keywords: Mass spectrometry; Metabolism; Metabolomics; Phytochemical genomics; Quantitative trait loci; Rice