title: Tuberculosis following kidney transplantation: report of paediatric case.
abstract: Recipients of solid organ transplantation are, because of immunosuppressive therapy, at high risk to develop opportunistic infections including tuberculosis (TB). The incidence, clinical manifestations, and optimal diagnostic tests of this disease in this population have not been adequately defined. In this paper, we report a case of 13 year-old boy who developed pulmonary tuberculosis following a second renal transplantation from a deceased donor. The described case points diagnostic difficulties of the tuberculosis disease which are due to insidious and non specific clinical presentation. Also, the treatment is delicate because interaction between immunosuppressive drugs and antituberculosis drugs.
authors.affiliation: Pediatric Nephrology Department, Charles Nicolle Hospital, Tunis, Tunisia.
authors.forename: Kamel
authors.initials: K
authors.lastname: Abidi
authors.affiliation: Pediatric Nephrology Department, Charles Nicolle Hospital, Tunis, Tunisia.
authors.forename: Manel
authors.initials: M
authors.lastname: Jellouli
authors.affiliation: Pediatric Nephrology Department, Charles Nicolle Hospital, Tunis, Tunisia.
authors.forename: Yousra
authors.initials: Y
authors.lastname: Hammi
authors.affiliation: Pediatric Nephrology Department, Charles Nicolle Hospital, Tunis, Tunisia.
authors.forename: Tahar
authors.initials: T
authors.lastname: Gargah
mesh_terms: D000293:Adolescent; D000995:Antitubercular Agents / Q000627:therapeutic use*; D004347:Drug Interactions; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects / Q000627:therapeutic use*; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D009894:Opportunistic Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology
chemical_list: D000995:Antitubercular Agents; D007166:Immunosuppressive Agents
keywords: Pulmonary tuberculosis; child; renal failure; renal transplantation