title: Impact of food animal trade on the spread of mcr-1-mediated colistin resistance, Tunisia, July 2015.
abstract: We report a high prevalence of MCR-1 and CTX-M-1-producing Escherichia coli in three Tunisian chicken farms. Chickens were imported from France or derived from French imported chicks. The same IncHI2-type plasmid reported to carry those genes in cattle in France and in a food sample in Portugal was found in Tunisian chickens of French origin. This suggests a significant impact of food animal trade on the spread of mcr-1-mediated colistin resistance in Europe.
authors.affiliation: Unité Antibiorésistance et Virulence Bactériennes, ANSES Site de Lyon, Lyon, France.
authors.forename: Raoudha
authors.initials: R
authors.lastname: Grami
authors.forename: Wejdene
authors.initials: W
authors.lastname: Mansour
authors.forename: Wahib
authors.initials: W
authors.lastname: Mehri
authors.forename: Olfa
authors.initials: O
authors.lastname: Bouallègue
authors.forename: Noureddine
authors.initials: N
authors.lastname: Boujaâfar
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Madec
authors.forename: Marisa
authors.initials: M
authors.lastname: Haenni
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D002645:Chickens; D003091:Colistin / Q000494:pharmacology*; D003132:Commerce; D024881:Drug Resistance, Bacterial; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics*; D004927:Escherichia coli Infections / Q000097:blood / Q000188:drug therapy / Q000453:epidemiology*; D005516:Food Microbiology; D005602:France; D005838:Genotype; D006801:Humans; D008460:Meat / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D010455:Peptides / Q000235:genetics*; D010957:Plasmids; D015995:Prevalence; D014416:Tunisia; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D000900:Anti-Bacterial Agents; C484884:MCR 14 peptide; D010455:Peptides; C055184:beta-lactamase TEM-3; D001618:beta-Lactamases; D003091:Colistin
keywords: E. coli; Tunisia; chicken; colistin; food animal trade; mcr-1