title: The ROCKs on which tumour cells thrive.
abstract: A new study reveals that the ROCK proteins play key roles in the formation of tumours in mice.
authors.affiliation: CRUK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Simon
authors.identifier: 0000-0003-1082-8218
authors.initials: S
authors.lastname: Wilkinson
authors.affiliation: CRUK Edinburgh Centre, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, United Kingdom.
authors.forename: Margaret C
authors.initials: MC
authors.lastname: Frame
mesh_terms: D000818:Animals; D051379:Mice; D009369:Neoplasms; D054460:rho-Associated Kinases / Q000378:metabolism*
chemical_list: D054460:rho-Associated Kinases
keywords: ROCK; actin cytoskeleton; actomyosin contractility; cancer biology; cell biology; cell proliferation; cellular senescence; mouse; rho kinase