title: Musculoskeletal melioidosis: An under-diagnosed entity in developing countries.
abstract: BACKGROUND
  Melioidosis is a saprophytic infectious disease caused by Gram-negative soil-dwelling bacillus Burkholderia pseudomallei.
  
  
  METHODS
  We report three cases of musculoskeletal melioidosis that are presented to our department from 2011 to 2013.
  
  
  RESULTS
  One of the patients died due to post-septicemic ARDS. The other two patients have recovered fully and are followed up for minimum of 6 months. There were no recurrences.
  
  
  CONCLUSIONS
  Though musculoskeletal infection due to melioidosis is not common in India, new cases are being reported from Karnataka, Goa and Southern Maharashtra. The need for diagnosing this entity is due to the fact that the septicemic form has a mortality rate that exceeds 90%, and though culture sensitivity report shows susceptibility to various antibiotics, the infection responds to only specific set of antibiotics i.e. intravenous ceftazidime and combination of trimethoprim and sulfamethoxazole.
authors.affiliation: Department of Orthopaedics, Hinduja Hospital and MRC, Mahim, India.
authors.forename: Hitendra G
authors.initials: HG
authors.lastname: Patil
authors.affiliation: Department of Orthopaedics, Hinduja Hospital and MRC, Mahim, India.
authors.forename: Manit
authors.initials: M
authors.lastname: Gundavda
authors.affiliation: Department of Orthopaedics, Hinduja Hospital and MRC, Mahim, India.
authors.forename: Vivek
authors.initials: V
authors.lastname: Shetty
authors.affiliation: Infectious Diseases, Hinduja Hospital and MRC, Mahim, India.
authors.forename: Rajeev
authors.initials: R
authors.lastname: Soman
authors.affiliation: Infection Control Committee, Hinduja Hospital and MRC, Mahim, India.
authors.forename: Camilla
authors.initials: C
authors.lastname: Rodriques
authors.affiliation: Department of Orthopaedics, Hinduja Hospital and MRC, Mahim, India.
authors.forename: Vikas M
authors.initials: VM
authors.lastname: Agashe
keywords: Burkholderia pseudomallei; Melioidosis; Musculoskeletal infection