title: Novel BODIPY-based Ru(II) and Ir(III) metalla-rectangles: cellular localization of compounds and their antiproliferative activities.
abstract: The first examples of Ru(ii) and Ir(iii) metalla-rectangles [1](4+)-[4](4+) containing a BODIPY-based linker are reported; some of these compounds exhibited highly selective anticancer activity and interact strongly with DNA as well as protein. The characteristic green fluorescence of a BODIPY ligand and associated aggregation-induced emission (AIE) permitted visualization of compounds inside the cells using confocal microscopy.
authors.affiliation: Department of Energy and Chemical Engineering, Incheon National University, Incheon 406-772, Republic of Korea. gjngupt@gmail.com cylee@inu.ac.kr.
authors.forename: Gajendra
authors.initials: G
authors.lastname: Gupta
authors.affiliation: Division of Molecular Medicine, Bose Institute, P-1/12, CIT Scheme VIIM, Kolkata-700054, West Bengal, India. mandaln@rediffmail.com.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Das
authors.affiliation: Division of Molecular Medicine, Bose Institute, P-1/12, CIT Scheme VIIM, Kolkata-700054, West Bengal, India. mandaln@rediffmail.com.
authors.forename: Nikhil Baban
authors.initials: NB
authors.lastname: Ghate
authors.affiliation: Department of Energy and Chemical Engineering, Incheon National University, Incheon 406-772, Republic of Korea. gjngupt@gmail.com cylee@inu.ac.kr.
authors.forename: Takhyeon
authors.initials: T
authors.lastname: Kim
authors.affiliation: Department of Chemistry, Chonnam National University, Gwangju 500-757, Republic of Korea.
authors.forename: Ji Yeon
authors.initials: JY
authors.lastname: Ryu
authors.affiliation: Department of Chemistry, Chonnam National University, Gwangju 500-757, Republic of Korea.
authors.forename: Junseong
authors.initials: J
authors.lastname: Lee
authors.affiliation: Division of Molecular Medicine, Bose Institute, P-1/12, CIT Scheme VIIM, Kolkata-700054, West Bengal, India. mandaln@rediffmail.com.
authors.forename: Nripendranath
authors.initials: N
authors.lastname: Mandal
authors.affiliation: Department of Energy and Chemical Engineering, Incheon National University, Incheon 406-772, Republic of Korea. gjngupt@gmail.com cylee@inu.ac.kr.
authors.forename: Chang Yeon
authors.initials: CY
authors.lastname: Lee
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D045744:Cell Line, Tumor; D049109:Cell Proliferation; D018360:Crystallography, X-Ray; D006801:Humans; D007495:Iridium / Q000737:chemistry*; D012428:Ruthenium / Q000737:chemistry*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D007495:Iridium; D012428:Ruthenium