title: Intraoperative high-field MRI maximizes the extent of resection in intraventricular central neurocytoma surgery.
abstract: Central neurocytoma (CN) is a rare benign neuronal tumor of the ventricular system. Microsurgical resection is considered to be the mainstay of treatment for intraventricular CN, and the extent of resection is the most important prognostic factor. We describe our initial experience in the management of intraventricular CN with intraoperative MRI together with microscope-based neuronavigation. During a 5year period between February 2009 and June 2014, 18 consecutive patients with histologically proven CN were included in this study. Gross total tumor resection was achieved in 88.9% (16/18) of patients. There were no perioperative deaths, and the overall complication rate was 61.1% (11/18). The Karnofsky Performance Status score at the last follow-up was 100 in eight (44.4%), 90 in seven (38.9%), and ⩽70 in three patients (16.7%). We conclude that intraoperative high-field MRI combined with microscope-based neuronavigation can maximize the extent of resection in intraventricular CN surgery and minimize the risks of neurological impairment.
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China; Department of Neurosurgery, Air Force General Hospital of the Chinese PLA, Haidian District, Beijing, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Anesthesiology, Beijing Military General Hospital, Beijing, China.
authors.forename: Li
authors.initials: L
authors.lastname: Ma
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Zhe
authors.initials: Z
authors.lastname: Xue
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Xiao-Lei
authors.initials: XL
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Xin-Guang
authors.initials: XG
authors.lastname: Yu
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Wu
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China.
authors.forename: Bai-Nan
authors.initials: BN
authors.lastname: Xu
authors.affiliation: Department of Neurosurgery, Chinese PLA General Hospital, 28 Fuxing Road, Haidian District, Beijing 100853, China. Electronic address: zh_sun301@126.com.
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D002551:Cerebral Ventricle Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008866:Microsurgery / Q000009:adverse effects / Q000379:methods*; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D018306:Neurocytoma / Q000000981:diagnostic imaging* / Q000601:surgery*; D038361:Neuronavigation / Q000379:methods*; D017063:Outcome Assessment, Health Care; D055815:Young Adult
keywords: Central neurocytoma; Complication; Intraoperative MRI; Neuronavigation; Surgical management