title: Neuroimaging.
abstract: Imaging is integral to the management of patients with brain tumors. Conventional structural imaging provides exquisite anatomic detail but remains limited in the evaluation of molecular characteristics of intracranial neoplasms. Quantitative and physiologic biomarkers derived from advanced imaging techniques have been increasingly utilized as problem-solving tools to identify glioma grade and assess response to therapy. This chapter provides a comprehensive overview of the imaging strategies used in the clinical assessment of patients with gliomas and describes how novel imaging biomarkers have the potential to improve patient management.
authors.affiliation: Radiological Sciences, Ronald Reagan Medical Center, Los Angeles, CA, USA. Electronic address: wpope@mednet.ucla.edu.
authors.forename: Whitney B
authors.initials: WB
authors.lastname: Pope
authors.affiliation: Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Djoukhadar
authors.affiliation: Wolfson Molecular Imaging Centre, University of Manchester, Manchester, UK.
authors.forename: Alan
authors.initials: A
authors.lastname: Jackson
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D005910:Glioma / Q000000981:diagnostic imaging*; D006801:Humans; D059906:Neuroimaging
keywords: MRI; PET; diffusion-weighted imaging; glioblastoma; glioma; imaging; perfusion-weighted imaging; spectroscopy