title: Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome.
abstract: Methylene blue (MB) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, MB can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents. We describe a case of serotonin syndrome in a patient who received MB for vasoplegic syndrome after left ventricular assist device implantation and discuss its presentation and management.
authors.affiliation: Department of Pharmacy Services, Henry Ford Hospital, Detroit, Michigan.
authors.forename: Laura
authors.initials: L
authors.lastname: Hencken
authors.affiliation: Department of Pharmacy Services, Henry Ford Hospital, Detroit, Michigan.
authors.forename: Long
authors.initials: L
authors.lastname: To
authors.affiliation: Department of Cardiology, Henry Ford Hospital, Detroit, Michigan.
authors.forename: Nancy
authors.initials: N
authors.lastname: Ly
authors.affiliation: Department of Cardiac Surgery, Henry Ford Hospital, Detroit, Michigan.
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Morgan
mesh_terms: D015283:Citalopram / Q000009:adverse effects; D004357:Drug Synergism; D005260:Female; D006353:Heart-Assist Devices; D006801:Humans; D008751:Methylene Blue / Q000008:administration & dosage / Q000009:adverse effects*; D008875:Middle Aged; D019919:Prosthesis Implantation; D020230:Serotonin Syndrome / Q000139:chemically induced*; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects; D012720:Severity of Illness Index; D056987:Vasoplegia / Q000628:therapy*
chemical_list: D015283:Citalopram; D008751:Methylene Blue; D017367:Selective Serotonin Reuptake Inhibitors