title: Oxidative Radical Addition/Cyclization Cascade for the Construction of Carbonyl-Containing Quinoline-2,4(1H,3H)-Diones.
abstract: Oxidative radical addition/cyclization cascade of o-cyanoarylacrylamides with α-keto acids as well as aldehydes is reported. This transformation exhibits a wide substrate scope and significant functional group tolerance and provides a convenient and highly efficient access to carbonyl-containing quinoline-2,4(1H,3H)-diones. A possible mechanism for the transformation is proposed.
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology , Kunming 650500, P. R. China.
authors.forename: Shi-Sheng
authors.initials: SS
authors.lastname: Wang
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology , Kunming 650500, P. R. China.
authors.forename: Hong
authors.initials: H
authors.lastname: Fu
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology , Kunming 650500, P. R. China.
authors.forename: Yuehai
authors.initials: Y
authors.lastname: Shen
authors.affiliation: Key Laboratory of Synthetic and Natural Functional Molecule Chemistry of Ministry of Education, Department of Chemistry & Materials Science, Northwest University , Xi'an 710127, P. R. China.
authors.forename: Meng
authors.initials: M
authors.lastname: Sun
authors.affiliation: Faculty of Life Science and Technology, Kunming University of Science and Technology , Kunming 650500, P. R. China.
authors.forename: Ya-Min
authors.initials: YM
authors.lastname: Li