title: Translational Meta-analytical Methods to Localize the Regulatory Patterns of Neurological Disorders in the Human Brain.
abstract: The task of mapping neurological disorders in the human brain must be informed by multiple measurements of an individual's phenotype - neuroimaging, genomics, and behavior. We developed a novel meta-analytical approach to integrate disparate resources and generated transcriptional maps of neurological disorders in the human brain yielding a purely computational procedure to pinpoint the brain location of transcribed genes likely to be involved in either onset or maintenance of the neurological condition.
authors.affiliation: Stanford Graduate Fellow, Graduate Program in Biomedical Informatics.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Sochat
authors.affiliation: Department of Pediatrics, Systems Medicine Division Stanford University School of Medicine Stanford, CA 94305.
authors.forename: Maude
authors.initials: M
authors.lastname: David
authors.affiliation: Stanford Graduate Fellow, Graduate Program in Biomedical Informatics.
authors.forename: Dennis P
authors.initials: DP
authors.lastname: Wall
mesh_terms: D001921:Brain; D001931:Brain Mapping; D006801:Humans; D009422:Nervous System Diseases / Q000000981:diagnostic imaging*; D059906:Neuroimaging; D010363:Pattern Recognition, Automated; D010641:Phenotype