title: How Ovarian Cancer Evades Immune Scrutiny.
abstract: Although dendritic cells are abundant in ovarian tumors, scientists have been puzzled that these cells aren't immunostimulatory. New research reveals a role for the protein SATB1, which is transiently required during ovarian-associated dendritic cell maturation-its unremitting expression in these cells drives them to acquire an inflammatory, immunosuppressive phenotype.
authors.forename: Alissa
authors.initials: A
authors.lastname: Poh
mesh_terms: D003713:Dendritic Cells / Q000378:metabolism; D005260:Female; D006801:Humans; D035683:MicroRNAs / Q000235:genetics; D010051:Ovarian Neoplasms / Q000235:genetics / Q000276:immunology* / Q000378:metabolism; D019139:Tumor Escape / Q000276:immunology*
chemical_list: C524942:MIRN155 microRNA, human; D035683:MicroRNAs