title: Clozapine-induced palilalia?.
abstract: BACKGROUND
  Palilalia is an acquired speech disorder characterised by involuntary and spontaneous repetition of words or phrases two or more times in a row. It can occur in a variety of disorders including postencephalic parkinsonism, pseudobulbar palsy, schizophrenia, Gilles de la Tourette syndrome and others.
  
  
  METHODS
  We describe a case of a 28-year-old man with refractory schizophrenia that developed palilalia with 300 mg of clozapine. In the patient evaluation we found unspecific alterations in the electroencephalogram, with normal blood tests and cerebral magnetic resonance imaging. Palilalia disappeared with lowering doses of clozapine.
  
  
  CONCLUSIONS
  The appearance of palilalia induced by clozapine is a rare pharmacologic side-effect which physicians should be familiarised with when evaluating this symptom presentation.
authors.affiliation: Department of Psychiatry, Oporto Medical School, Porto, Portugal.
authors.forename: Jacinto C
authors.initials: JC
authors.lastname: Azevedo
authors.affiliation: Department of Psychiatry, Hospital São João, Porto, Portugal.
authors.forename: Rui
authors.initials: R
authors.lastname: Lopes
authors.affiliation: Department of Psychiatry, Oporto Medical School, Porto, Portugal.
authors.forename: Rosário
authors.initials: R
authors.lastname: Curral
authors.affiliation: Department of Psychiatry, Oporto Medical School, Porto, Portugal.
authors.forename: Manuel F
authors.initials: MF
authors.lastname: Esteves
authors.affiliation: Department of Psychiatry, Hospital São João, Porto, Portugal.
authors.forename: Rui
authors.initials: R
authors.lastname: Coelho
authors.affiliation: Department of Psychiatry, Oporto Medical School, Porto, Portugal.
authors.forename: Antonio
authors.initials: A
authors.lastname: Roma-Torres