title: [Treatment of Steroid-induced Osteonecrosis of Femoral Head by Porous Tantalum Rod and Gugutou Huaisiyu Capsule].
abstract: OBJECTIVE
  To observe the curative effect of porous tantalum rod and Gugutou Huaisiyu Capsule (GHC) for steroid-induced osteonecrosis of femoral head (SONFH).
  
  
  METHODS
  A total 60 hips of 50 SONFH patients were randomly assigned to the treatment group and the control group according to grouping time, 25 in each group (30 hips). Patients in the control group were implanted with porous tantalum rod, while those in the treatment group additionally took GHC (5 pills each time, three time per day for 2 successive months; and then twice per day for 4 successive months). Then all patients were followed-up to observe Harris hip score. The curative effect and the femoral head survival time were assessed.
  
  
  RESULTS
  A total of 49 patients (59 hips) were followed-up. The Harris hip score of the two groups at the final follow-up was significantly improved after treatment, with statistical difference when compared with before treatment (P < 0.01). Besides, it was higher in the treatment group than in the control group. The curative effect and the survival time were superior in the treatment group, with statistical difference when compared with the control group (P < 0.05).
  
  
  CONCLUSIONS
  Porous tantalum rod combined GHC got better effect in treating SONFH. It could significantly improve the function of affected hips and prolong the survival time of femoral head.
authors.forename: Xu-yi
authors.initials: XY
authors.lastname: Tan
authors.forename: Fei-fei
authors.initials: FF
authors.lastname: Gao
authors.forename: Shu-tu
authors.initials: ST
authors.lastname: Gao
authors.forename: You-wen
authors.initials: YW
authors.lastname: Liu
authors.forename: Xian-tao
authors.initials: XT
authors.lastname: Chen
authors.forename: Li-yun
authors.initials: LY
authors.lastname: Liu
mesh_terms: D002214:Capsules; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D005271:Femur Head Necrosis / Q000188:drug therapy*; D006801:Humans; D019736:Prostheses and Implants; D013256:Steroids / Q000009:adverse effects; D013635:Tantalum
chemical_list: D002214:Capsules; D004365:Drugs, Chinese Herbal; D013256:Steroids; D013635:Tantalum