title: Complete Durable Response From Carboplatin and Olaparib in a Heavily Pretreated Triple-Negative Metastatic Breast Cancer With Germline BRCA2 and "BRCAness" Mutations.
authors.affiliation: Internal Medicine and Taussig Cancer Institute, Cleveland Clinic Foundation; and Moll Cancer Center, Fairview Hospital, Cleveland Clinic, Cleveland, OH hongs@ccf.org.
authors.forename: Sanghee
authors.initials: S
authors.lastname: Hong
authors.affiliation: Internal Medicine and Taussig Cancer Institute, Cleveland Clinic Foundation; and Moll Cancer Center, Fairview Hospital, Cleveland Clinic, Cleveland, OH.
authors.forename: Pauline
authors.initials: P
authors.lastname: Funchain
authors.affiliation: Internal Medicine and Taussig Cancer Institute, Cleveland Clinic Foundation; and Moll Cancer Center, Fairview Hospital, Cleveland Clinic, Cleveland, OH.
authors.forename: Abdo
authors.initials: A
authors.lastname: Haddad
authors.affiliation: Internal Medicine and Taussig Cancer Institute, Cleveland Clinic Foundation; and Moll Cancer Center, Fairview Hospital, Cleveland Clinic, Cleveland, OH.
authors.forename: Joseph
authors.initials: J
authors.lastname: Crowe
authors.affiliation: Internal Medicine and Taussig Cancer Institute, Cleveland Clinic Foundation; and Moll Cancer Center, Fairview Hospital, Cleveland Clinic, Cleveland, OH.
authors.forename: Nancy
authors.initials: N
authors.lastname: Dalpiaz
authors.affiliation: Internal Medicine and Taussig Cancer Institute, Cleveland Clinic Foundation; and Moll Cancer Center, Fairview Hospital, Cleveland Clinic, Cleveland, OH.
authors.forename: Jame
authors.initials: J
authors.lastname: Abraham
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology / Q000627:therapeutic use*; D024682:BRCA2 Protein / Q000235:genetics*; D016190:Carboplatin / Q000008:administration & dosage; D005260:Female; D018095:Germ-Line Mutation; D006801:Humans; D008875:Middle Aged; D010793:Phthalazines / Q000008:administration & dosage; D010879:Piperazines / Q000008:administration & dosage; D016896:Treatment Outcome; D064726:Triple Negative Breast Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000235:genetics
chemical_list: D024682:BRCA2 Protein; C551750:BRCA2 protein, human; D010793:Phthalazines; D010879:Piperazines; D016190:Carboplatin; C531550:olaparib