title: Increased (18)F-FDG uptake in the trapezius muscle in patients with spinal accessory neuropathy.
abstract: To investigate (18)F-fluorodeoxyglucose (FDG) positron emission tomography (PET) signal changes of denervated muscles in patients with electrophysiologically confirmed neuropathy.
  
  
  METHODS
  This is a case series of three cancer patients who were referred to the electromyography laboratory in 2013 due to shoulder discomfort after surgery including neck dissection. Spinal accessory neuropathy was diagnosed based on electrophysiological studies. Patients' medical history, electrophysiological data, and FDG-PET images were reviewed retrospectively. Mean standard uptake values (SUV) of trapezius muscles were measured.
  
  
  RESULTS
  The patients (3 men, aged 61-78years) showed spinal accessory neuropathy with different degrees of severity. In all patients, preoperative or postoperative FDG-PET showed increased FDG uptake in the ipsilateral trapezius muscle. These results were compatible with previously reported glucose hypermetabolism in denervated skeletal muscles.
  
  
  CONCLUSIONS
  This is the first clinical report of increased FDG uptake by denervated muscles in electrophysiologically confirmed neuropathy.
authors.affiliation: Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehak-Ro, Jongno-Gu, Seoul 03080, Republic of Korea. Electronic address: seunghak@gmail.com.
authors.forename: Seung Hak
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehak-Ro, Jongno-Gu, Seoul 03080, Republic of Korea. Electronic address: hgseo80@gmail.com.
authors.forename: Han Gil
authors.initials: HG
authors.lastname: Seo
authors.affiliation: Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Hospital, 101, Daehak-Ro, Jongno-Gu, Seoul 03080, Republic of Korea.
authors.forename: Byung-Mo
authors.initials: BM
authors.lastname: Oh
authors.affiliation: Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Republic of Korea.
authors.forename: Hongyoon
authors.initials: H
authors.lastname: Choi
authors.affiliation: Department of Nuclear Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Institute of Radiation Medicine, Medical Research Center, Seoul National University, Seoul, Republic of Korea.
authors.forename: Gi Jeong
authors.initials: GJ
authors.lastname: Cheon
authors.affiliation: Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
authors.forename: Shi-Uk
authors.initials: SU
authors.lastname: Lee
mesh_terms: D020436:Accessory Nerve Diseases / Q000473:pathology*; D000368:Aged; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D007839:Functional Laterality; D006801:Humans; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D064171:Superficial Back Muscles / Q000000981:diagnostic imaging*
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: (18)F-FDG; Muscle denervation; Positron emission tomography; Spinal accessory neuropathy