title: Primary Non-Hodgkin's Lymphoma of the Vulva: A Case Report and Literature Review.
abstract: The aim of this study was to add a new case of primary non-Hodgkin's malignant lymphoma of the vulva to the literature and to review the current literature.We searched the PubMed/MEDLINE databases for previous case reports using the key words "non-Hodgkin's malignant lymphoma of the vulva," "vulvar lymphoma," and "primary vulvar non-Hodgkin's lymphoma." We found 29 cases of primary vulvar non-Hodgkin's malignant lymphoma of the vulva reported until 2015. Among them, only 8 cases of diffuse large B-cell lymphoma (DLBCL), classified according to the most recent 2008 WHO classification, were reported.Moreover, only few studies reported the therapeutic management and clinical follow-up of patients affected by this condition.Due to its uncommon presentation, the primary non-Hodgkin's malignant lymphoma of the vulva can be undiagnosed; thus gynecologists, oncologists, and pathologists should be aware of this condition, as a correct diagnosis is essential for an appropriate therapeutic management.
authors.affiliation: From the Gynecological Oncology Unit (NC, EL, FS); Division of Pathology (LA, VC); Cellular Therapy and High-Dose Chemotherapy Unit (MR); and Clinical and Experimental Onco-Hematology Unit (PB); CRO Centro di Riferimento Oncologico-National Cancer Institute, Aviano, Italy.
authors.forename: Nicolò
authors.initials: N
authors.lastname: Clemente
authors.forename: Lara
authors.initials: L
authors.lastname: Alessandrini
authors.forename: Maurizio
authors.initials: M
authors.lastname: Rupolo
authors.forename: Pietro
authors.initials: P
authors.lastname: Bulian
authors.forename: Emilio
authors.initials: E
authors.lastname: Lucia
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Canzonieri
authors.forename: Francesco
authors.initials: F
authors.lastname: Sopracordevole
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D016403:Lymphoma, Large B-Cell, Diffuse / Q000175:diagnosis*; D009367:Neoplasm Staging; D049268:Positron-Emission Tomography; D014057:Tomography, X-Ray Computed; D014846:Vulvar Neoplasms / Q000175:diagnosis*