title: Iatrogenic Cushing's Syndrome After Topical Steroid Therapy for Psoriasis.
abstract: Glucocorticoids are used for the treatment of many diseases, such as inflammatory, allergic, autoimmune, and neoplastic diseases. They can be used in the form of topical, oral, inhalable, rectal, and intra-articular agents. Many topical steroid-related iatrogenic Cushing's syndrome cases affecting especially children have been reported in the literature. Topical steroid-related Cushing's syndrome is rarely seen in adults. In this report, we present the case of a 32-year-old male patient with iatrogenic Cushing's syndrome related to long-term clobetasol propionate treatment for psoriasis. In the context of such treatment, the glucocorticoid withdrawal problem has to be overcome. At present there is no consensus on steroid withdrawal. Patients on long-term glucocorticoid treatment must be evaluated for potential adverse effects and withdrawal symptoms by their physician and their endocrinologist.
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Birsen
authors.initials: B
authors.lastname: Sahıp
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Celık
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Semra
authors.initials: S
authors.lastname: Ayturk
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kucukarda
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Onur
authors.initials: O
authors.lastname: Mert
authors.affiliation: Department of Dermatology, Trakya University, Edirne, Turkey.
authors.forename: Nejla
authors.initials: N
authors.lastname: Dıncer
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Sıbel
authors.initials: S
authors.lastname: Guldıken
authors.affiliation: Department of Internal Medicine, Division of Endocrinology, Trakya University, Edirne, Turkey.
authors.forename: Armagan
authors.initials: A
authors.lastname: Tugrul
keywords: Iatrogenic Cushing's syndrome; psoriasis; topical steroid