title: Histiocytoid Sweet's syndrome in a patient with myelodsyplastic syndrome: report and review of the literature.
abstract: The neutrophilic dermatoses are a group of disorders characterized by skin lesions for which histological examination reveals intense epidermal and/or dermal inflammatory infiltrates composed primarily of neutrophils without evidence of infection. The myelodysplastic syndromes consist of a heterogeneous group of malignant hematopoietic stem cell disorders characterized by dysplastic and inadequate blood cell production with a variable risk of transformation to acute leukemia. Rarely, histiocytoid Sweet's syndrome occurring in patients with myelodysplastic syndrome has been described. We present a case of a 66-year-old woman with a history of myelodysplastic syndrome who developed histiocytoid Sweet's syndrome. We also review the literature and characterize patients with myelodysplastic syndrome who have developed histiocytoid Sweet's syndrome.
authors.affiliation: Medical School, Louisiana State University Health Sciences Center, New Orleans, LA, USA.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Shalaby
authors.affiliation: Department of Dermatology, Louisiana State University, New Orleans, LA, USA.
authors.forename: Ryan R
authors.initials: RR
authors.lastname: Riahi
authors.affiliation: Dermpath Diagnostics, Pompano Beach, FL, USA.
authors.forename: Les B
authors.initials: LB
authors.lastname: Rosen
authors.affiliation: Department of Dermatology, Louisiana State University, New Orleans, LA, USA; Soine Dermatology & Aesthetics, New Orleans, LA, USA.
authors.forename: Erik J
authors.initials: EJ
authors.lastname: Soine
keywords: histiocytoid Sweet’s; myelodysplasia; myelodysplastic; sweet; sweet’s; syndrome