title: Characteristics of particulate and non-particulate corticosteroids. Indications for their use in chronic pain treatments.
abstract: Corticosteroids been used frequently in pain treatments since the middle of last century (1952). Due to a review of the complications as a result of their application in epidural injections, the United States of America Food and Drug Administration (FDA) issued an «alert controversy» requesting that a warning label should be added to injectable corticosteroids, where risks must be described (loss of sight, brain damage, paralysis and death) when administering by this route. It must be mentioned that there are different types of corticosteroids with diverse characteristics, which as a result, may produce different side-effects. Due to the aforementioned developments, the controversies that have arisen, and the lack of well-conducted studies on the use of steroids in epidural injections, we must begin by reviewing their indications in different pain conditions.
authors.affiliation: Servicio de Anestesiología Reanimación y Tratamiento del Dolor, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España. Electronic address: dr.orduna.dolor@gmail.com.
authors.forename: J M
authors.initials: JM
authors.lastname: Orduña-Valls
authors.affiliation: Servicio de Anestesiología Reanimación y Tratamiento del Dolor, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España.
authors.forename: C L
authors.initials: CL
authors.lastname: Nebreda-Clavo
authors.affiliation: Servicio de Anestesiología Reanimación y Tratamiento del Dolor, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España.
authors.forename: P
authors.initials: P
authors.lastname: López-Pais
authors.affiliation: Unidad del Dolor, Centro Médico Quiron-Teknon, Barcelona, España.
authors.forename: D
authors.initials: D
authors.lastname: Torres-Rodríguez
authors.affiliation: Departamento de Ciencias Morfológicas, Universidad de Santiago de Compostela, Santiago de Compostela, A Coruña, España.
authors.forename: M
authors.initials: M
authors.lastname: Quintans-Rodríguez
authors.affiliation: Servicio de Anestesiología Reanimación y Tratamiento del Dolor, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, A Coruña, España.
authors.forename: J
authors.initials: J
authors.lastname: Álvarez-Escudero
mesh_terms: D000305:Adrenal Cortex Hormones; D059350:Chronic Pain / Q000188:drug therapy*; D005938:Glucocorticoids; D006801:Humans; D007268:Injections, Epidural; D014481:United States; D014486:United States Food and Drug Administration
chemical_list: D000305:Adrenal Cortex Hormones; D005938:Glucocorticoids
keywords: Betametasona; Betamethasone; Corticoide; Corticoide particulado; Dexametasona; Dexamethasone; Epidural transforaminal; Particulate steroids; Steroids; Transforaminal epidural; Triamcinolona; Triamcinolone