title: Oral Biofilm Architecture at the Microbial Scale.
abstract: The application of Spectral Imaging FISH to oral biofilm samples has permitted the direct, simultaneous observation of up to nine different bacterial taxa. This has revealed a complex yet organized microbial architecture, identifying the key microorganisms in the community and detecting the existing interspecies physical interactions at the micron scale.
authors.affiliation: FISABIO Foundation, Center for Advanced Research in Public Health, Valencia, Spain.
authors.forename: Maria D
authors.initials: MD
authors.lastname: Ferrer
authors.affiliation: FISABIO Foundation, Center for Advanced Research in Public Health, Valencia, Spain. Electronic address: mira_ale@gva.es.
authors.forename: Alex
authors.initials: A
authors.lastname: Mira
mesh_terms: D001419:Bacteria / Q000145:classification*; D006801:Humans; D064307:Microbiota; D009055:Mouth / Q000382:microbiology*; D058974:Phylogeography
keywords: CLASI-FISH; biofilm; human microbiome; microbial interactions