title: Long noncoding RNAs in regulating adipogenesis: new RNAs shed lights on obesity.
abstract: Long noncoding RNAs (lncRNAs) are an emerging class of regulators involved in a myriad of biological processes. Recent studies have revealed that many lncRNAs play pivotal roles in regulating adipocyte development. Due to the prevalence of obesity and the serious effects of adiposity on human health and society development, it is necessary to summarize functions and recent advances of lncRNAs in adipogenesis. In this review, we highlight functional lncRNAs contributed to the regulation of adipogenesis, discussing their potential use as therapeutic targets to combat human obesity.
authors.affiliation: College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China.
authors.forename: Shengjuan
authors.initials: S
authors.lastname: Wei
authors.affiliation: Department of Animal Sciences, Washington State University, Pullman, WA, 99164, USA.
authors.forename: Min
authors.initials: M
authors.lastname: Du
authors.affiliation: Department of Animal Sciences, Washington State University, Pullman, WA, 99164, USA.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Jiang
authors.affiliation: Animal and Dairy Science, University of Georgia, Athens, GA, 30602-2771, USA.
authors.forename: Gary J
authors.initials: GJ
authors.lastname: Hausman
authors.affiliation: College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, 210095, People's Republic of China. lifanzhang@njau.edu.cn.
authors.forename: Lifan
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Animal Sciences, Washington State University, Pullman, WA, 99164, USA. dodson@wsu.edu.
authors.forename: Michael V
authors.initials: MV
authors.lastname: Dodson
mesh_terms: D017667:Adipocytes / Q000166:cytology; D050156:Adipogenesis / Q000235:genetics / Q000502:physiology*; D000273:Adipose Tissue / Q000473:pathology*; D002001:Adipose Tissue, Brown / Q000473:pathology; D052436:Adipose Tissue, White / Q000473:pathology; D000818:Animals; D005786:Gene Expression Regulation; D006801:Humans; D009765:Obesity / Q000235:genetics / Q000378:metabolism*; D062085:RNA, Long Noncoding / Q000235:genetics* / Q000378:metabolism*
chemical_list: C561566:HOTAIR long untranslated RNA, human; C577276:NEAT1 long non-coding RNA, human; D062085:RNA, Long Noncoding; C000607592:boundary associated long noncoding RNA-1, human; C405423:steroid receptor RNA activator
keywords: Adipose tissue; Beige cells; Blnc1; HOTAIR; NEAT1; SRA; ncRNAs