title: [MANIFESTATIONS OF EPIDEMIC PROCESS AND TRANSMISSION ROUTES OF CAUSATIVE AGENT OF ENTEROVIRUS SEROUS MENINGITIS].
abstract: OBJECTIVE
  Study the manifestations of epidemic process and leading transmission routes of causative agents of enterovirus serous meningitis (SM) by results of laboratory studies and epidemiologic examination of epidemic nidi.
  
  
  METHODS
  During 2010 - 2014 a study for enterovirus was carried out in cerebrospinal fluid in 743 patients, hospitalized into medical organizations of Perm with primary diagnosis "serous meningitis", feces of 426 individuals, that had communicated with patients with SM of enterovirus etiology; 827 water samples from the distribution network, 295 water samples from open water and 57 washes from surface of vegetables and fruits. All the samples were studied in polymerase chain reaction, part--by a virological method. Epidemiologic examination of 350 epidemic nidi of SM was carried out.
  
  
  RESULTS
  Enterovirus and (or) its RNA were detected in 62.0% of patients and 61.9% of individuals that had communicated with patients with enteroviris SM. ECHO 6 serotype enterovirus dominated among the causative agents. Maximum intensity of epidemic process of enterovirus SM, based on data from laboratory examination of patients, was detected in a group of organized pre-school and school age children during summer-autumn period.
  
  
  CONCLUSIONS
  . Examination of epidemic nidi and laboratory control of environmental objects have shown that CV causative agent transmission factors are, in particular, unboiled water from decentralized sources (boreholes, wells, springs), water from open waters during bathing, as well as fresh vegetables, fruits, berries and meals produced from them. .
authors.forename: V I
authors.initials: VI
authors.lastname: Sergevnin
authors.forename: M A
authors.initials: MA
authors.lastname: Tryasolobova
authors.forename: E V
authors.initials: EV
authors.lastname: Kudrevatykh
authors.forename: E Zh
authors.initials: EZh
authors.lastname: Kuzovnikova
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D004197:Disease Reservoirs / Q000821:virology*; D060766:Drinking Water / Q000821:virology; D004770:Enterovirus / Q000235:genetics / Q000302:isolation & purification* / Q000472:pathogenicity; D004769:Enterovirus Infections / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D062665:Epidemiological Monitoring; D005260:Female; D005618:Fresh Water / Q000821:virology; D005638:Fruit / Q000821:virology; D006801:Humans; D007223:Infant; D008297:Male; D008587:Meningitis, Viral / Q000134:cerebrospinal fluid / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D016133:Polymerase Chain Reaction; D012367:RNA, Viral / Q000235:genetics* / Q000302:isolation & purification; D012426:Russia / Q000453:epidemiology; D014675:Vegetables / Q000821:virology
chemical_list: D060766:Drinking Water; D012367:RNA, Viral