title: Evaluation of the Adherence to Continuous Glucose Monitoring in the Management of Type 1 Diabetes Patients on Sensor-Augmented Pump Therapy: The SENLOCOR Study.
abstract: BACKGROUND
  Continuous glucose monitoring (CGM) and sensor-augmented pump (SAP) therapy improve glucose control provided good adherence. In France, not only diabetologists, nurses, and dieticians but also nurses employed by homecare providers (HCPNs) are together involved in the initiation and/or follow-up of continuous subcutaneous insulin injection (CSII) and SAP training. The SENLOCOR Study is an observational study designed to assess SAP adherence over 6 months (primary objective). Secondary objectives included the impact of SAP on metabolic control and patients' satisfaction.
  
  
  METHODS
  CGM initiation (M0) was performed within 3 months after CSII. CGM adherence, defined by sensor wear >70% of the time, glycated hemoglobin (HbA1c) levels, and satisfaction questionnaires were collected at inclusion and at 3 (M3) and 6 (M6) months.
  
  
  RESULTS
  The analysis population was 234 patients, including 27 children. Of the physicians, 88.0% were involved in SAP education for the whole cohort (median time, 45 min), whereas HCPNs were involved in CGM training for 190 patients (81.2%) (median time: at M0, 156 min; at M3, 20 min). Good adherence was obtained in 86.1% (M0-M3) and 68.9% (M3-M6) of the patients. The HbA1c level decreased from 8.16 ± 1.35% (M0) to 7.67 ± 1.01% (M6) in 189 patients (change, -0.48%; 95% confidence interval, -0.64, -0.33). The percentage of patients who experienced severe hypoglycemia decreased from 20.7% (M0) to 13.6% (M3) and 13.3% (M6). Satisfaction scores were high.
  
  
  CONCLUSIONS
  In patients with type 1 diabetes, a 6-month training on SAP involving a multidisciplinary team, and especially HCPNs, improved metabolic control with a high level of adherence and satisfaction.
authors.affiliation: 1 Point Médical , Rond-Point de la Nation, Dijon, France .
authors.forename: Sylvie
authors.initials: S
authors.lastname: Picard
authors.affiliation: 2 Endocrinology-Diabetes Care Unit, Toulouse University Hospital , Toulouse, France .
authors.forename: Hélène
authors.initials: H
authors.lastname: Hanaire
authors.affiliation: 3 Endocrinology-Diabetes Care Unit, Dijon University Hospital , Dijon, France .
authors.forename: Sabine
authors.initials: S
authors.lastname: Baillot-Rudoni
authors.affiliation: 4 Endocrinology-Diabetes Care Pediatric Unit, Tours University Hospital , Tours, France .
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Gilbert-Bonnemaison
authors.affiliation: 5 Center of Clinical Research , Lyon, France .
authors.forename: Didier
authors.initials: D
authors.lastname: Not
authors.affiliation: 6 Endocrinology-Diabetes Care Unit, Caen University Hospital , Caen, France .
authors.forename: Yves
authors.initials: Y
authors.lastname: Reznik
authors.affiliation: 7 Endocrinology-Diabetes Care Unit, University of Lorraine , Vandoeuvre Lès Nancy, France .
authors.forename: Bruno
authors.initials: B
authors.lastname: Guerci
mesh_terms: D000293:Adolescent; D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D002648:Child; D015331:Cohort Studies; D003922:Diabetes Mellitus, Type 1 / Q000097:blood / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D006943:Hyperglycemia / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D007003:Hypoglycemia / Q000139:chemically induced / Q000175:diagnosis* / Q000453:epidemiology / Q000517:prevention & control; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D015994:Incidence; D007328:Insulin / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use; D007332:Insulin Infusion Systems / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D018670:Monitoring, Ambulatory; D010349:Patient Compliance; D010353:Patient Education as Topic; D017060:Patient Satisfaction; D000078329:Workforce; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; C517652:hemoglobin A1c protein, human