title: Oral ulcerations after placement of orthodontic braces and skin pustules after laser hair removal: novel inducers of pathergy reactions in new-onset Behçet's disease.
abstract: A 25-year-old man was admitted to our hospital, with fever, severe ulceration of the oral and pharyngeal mucosa, and pustules on his skin. These pathergy-like lesions had emerged after placement of orthodontic braces and laser therapy for hair removal, respectively. The patient's clinical condition, together with his ethnic background, pointed to the diagnosis of Behçet's disease. Treatment with colchicine and prednisone resulted in rapid improvement of his symptoms. Pathergy reactions in response to placement of dental braces and laser hair removal are a rare first presentation of Behçet's disease.
authors.affiliation: Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
authors.forename: Claire
authors.initials: C
authors.lastname: van de Ree-Pellikaan
authors.affiliation: Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
authors.forename: Rosalie M
authors.initials: RM
authors.lastname: Kiewiet-Kemper
authors.affiliation: Department of Rheumatology, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
authors.forename: Ilja
authors.initials: I
authors.lastname: Tchetverikov
authors.affiliation: Department of Internal Medicine, Albert Schweitzer Hospital, Dordrecht, The Netherlands.
authors.forename: Peter E
authors.initials: PE
authors.lastname: Westerweel
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D001528:Behcet Syndrome / Q000175:diagnosis* / Q000188:drug therapy; D003078:Colchicine / Q000627:therapeutic use; D005076:Exanthema / Q000209:etiology; D006204:Hair Removal; D006801:Humans; D008297:Male; D019226:Oral Ulcer / Q000209:etiology*; D016910:Orthodontic Brackets / Q000009:adverse effects*; D011241:Prednisone / Q000627:therapeutic use; D017445:Skin Diseases, Vascular / Q000209:etiology; D050257:Tubulin Modulators / Q000627:therapeutic use
chemical_list: D000893:Anti-Inflammatory Agents; D050257:Tubulin Modulators; D003078:Colchicine; D011241:Prednisone