title: [Effect of Low-Intensity 900 MHz Frequency Electromagnetic Radiation on Rat Brain Enzyme Activities Linked to Energy Metabolism].
abstract: The research deals with the effect of low-intensity 900 MHz frequency electromagnetic radiation (EMR), power density 25 μW/cm2, on the following rat brain and blood serum enzyme activities: creatine kinase (CK), playing a central role in the process of storing and distributing the cell energy, as well as alanine aminotransferase (ALT) and aspartate aminotransferase (AST) that play a key role in providing the conjunction of carbohydrate and amino acid metabolism. The comparative analysis of the changes in the enzyme activity studied at different times following the two-hour single, as well as fractional, radiation equivalent of the total time showed that the most radiosensitive enzyme is the brain creatine kinase, which may then be recommended as a marker of the radio frequency radiation impact. According to the analysis of the changing dynamics of the CK, ALT and AST activity level, with time these changes acquire the adaptive character and are directed to compensate the damaged cell energy metabolism.
authors.forename: M S
authors.initials: MS
authors.lastname: Petrosyan
authors.forename: L S
authors.initials: LS
authors.lastname: Nersesova
authors.forename: M G
authors.initials: MG
authors.lastname: Gazaryants
authors.forename: G O
authors.initials: GO
authors.lastname: Meliksetyan
authors.forename: M G
authors.initials: MG
authors.lastname: Malakyan
authors.forename: S A
authors.initials: SA
authors.lastname: Bajinyan
authors.forename: J I
authors.initials: JI
authors.lastname: Akopian
mesh_terms: D000222:Adaptation, Physiological; D000410:Alanine Transaminase / Q000097:blood / Q000378:metabolism*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood / Q000378:metabolism*; D001921:Brain / Q000201:enzymology / Q000378:metabolism / Q000528:radiation effects*; D003402:Creatine Kinase / Q000097:blood / Q000378:metabolism*; D004307:Dose-Response Relationship, Radiation; D060733:Electromagnetic Radiation; D004734:Energy Metabolism / Q000528:radiation effects*; D008297:Male; D051381:Rats; D014916:Whole-Body Irradiation
chemical_list: D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D003402:Creatine Kinase