title: Odontogenic myxoma with diffuse calcifications: a case report and review of a rare histologic feature.
abstract: Calcifications have been rarely reported in odontogenic myxoma. We describe here an additional case and review all reported cases. A 45-year-old female patient presented with a gingival swelling around a mobile mandibular left second molar. Radiographic investigation revealed a large multilocular radiolucent lesion of the posterior mandible. Microscopic examination revealed an odontogenic myxoma with numerous newly formed trabeculae of bone or cementum-like material present throughout the specimen, reminiscent of those seen in fibro-osseous lesions of the jaws. After total excision, regular follow-up of the patient showed gradual healing of the surgical defect. To our knowledge, only a few documented cases of odontogenic myxoma with calcifications have been reported in the literature. This histopathologic finding is rare but should not lead to the misdiagnosis of a central odontogenic fibroma, cemento-ossifying fibroma, fibro-osseous lesion, or low-grade osteosarcoma.
authors.affiliation: Associate Professor, Department of Oral Medicine and Surgery, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan. Electronic address: hmhammad@just.edu.jo.
authors.forename: Huda M
authors.initials: HM
authors.lastname: Hammad
authors.affiliation: Chief Resident, Department of Pathology and Laboratory Medicine, King Abdullah University Hospital, Irbid, Jordan.
authors.forename: Yousef M
authors.initials: YM
authors.lastname: Hasen
authors.affiliation: Consultant Oral and Maxillofacial Surgeon, Princess Basma Teaching Hospital, Jordan Ministry of Health, Irbid, Jordan.
authors.forename: Abd-Albaset M
authors.initials: AA
authors.lastname: Odat
authors.affiliation: Consultant Oral Medicine Specialist, Princess Basma Teaching Hospital, Jordan Ministry of Health, Irbid, Jordan.
authors.forename: Abeer M
authors.initials: AM
authors.lastname: Mikdadi
authors.affiliation: Associate Professor, Department of Oral Medicine and Surgery, Faculty of Dentistry, Jordan University of Science and Technology, Irbid, Jordan.
authors.forename: Rima A
authors.initials: RA
authors.lastname: Safadi
mesh_terms: D001706:Biopsy; D005260:Female; D018214:Fibroma, Ossifying / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D009232:Myxoma / Q000000981:diagnostic imaging / Q000473:pathology*; D009808:Odontogenic Tumors / Q000000981:diagnostic imaging / Q000473:pathology*; D011862:Radiography, Panoramic; D014057:Tomography, X-Ray Computed