title: Transcript Abundance Explains mRNA Mobility Data in Arabidopsis thaliana.
abstract: Recently, a large population of mRNA was shown to be able to travel between plant organs via sieve elements as a putative long-distance signaling molecule. However, a mechanistic basis by which transcripts are selected for transport has not yet been identified. Here, we show that experimental mRNA mobility data in Arabidopsis can be explained by transcript abundance and half-life. This suggests that the majority of identified mobile transcripts can be accounted for by non-sequence-specific movement of mRNA from companion cells into sieve elements.
authors.affiliation: Computational and Systems Biology and Crop Genetics, John Innes Centre, Norwich NR47 UH, United Kingdom.
authors.forename: Alexander
authors.initials: A
authors.lastname: Calderwood
authors.affiliation: Botanical Institute and Cluster of Excellence on Plant Sciences, University of Cologne, Cologne Biocenter, D-50674 Cologne, Germany.
authors.forename: Stanislav
authors.identifier: http://orcid.org/0000-0002-7416-6551
authors.initials: S
authors.lastname: Kopriva
authors.affiliation: Computational and Systems Biology and Crop Genetics, John Innes Centre, Norwich NR47 UH, United Kingdom richard.morris@jic.ac.uk.
authors.forename: Richard J
authors.identifier: http://orcid.org/0000-0003-3080-2613
authors.initials: RJ
authors.lastname: Morris
mesh_terms: D017360:Arabidopsis / Q000235:genetics; D001692:Biological Transport; D006207:Half-Life; D056004:Molecular Dynamics Simulation; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism*; D018749:RNA, Plant / Q000235:genetics / Q000378:metabolism
chemical_list: D012333:RNA, Messenger; D018749:RNA, Plant