title: Pathology of Haemonchus contortus in New World camelids in the southeastern United States: a retrospective review.
abstract: Most small ruminant farms in tropical climates are plagued by Haemonchus contortus, a hematophagous, abomasal parasite. Heavy burdens of this parasite can cause anemia, hypoproteinemia, weight loss, and mortality in susceptible animals. Haemonchus contortus is becoming a major health concern in New World camelids as well, namely llamas (Llama glama) and alpacas (Vicugna pacos), yet little research has been conducted regarding its prevalence or pathology in these species. Herein, we present a retrospective review of llamas and alpacas that were admitted to The University of Georgia Veterinary Teaching Hospital and Athens Diagnostic Laboratory between the years 2002 and 2013. Antemortem fecal egg count (FEC) estimates performed on 30 alpacas were negatively correlated with hematocrit, hemoglobin, and red blood cell count. Total protein was not significantly correlated with FEC. On postmortem examination, 55 of 198 camelids, including 2 from the aforementioned antemortem review, were infected with H. contortus, with llamas (42.6%) having a significantly higher infection rate than alpacas (22.2%). In 15.7% of the total cases, the parasite was the major cause of death. Common gross lesions included peritoneal, thoracic, and pericardial effusions, visceral pallor, subcutaneous edema, and serous atrophy of fat. Histologic lesions included centrilobular hepatic necrosis, hepatic atrophy, lymphoplasmacytic inflammation of the mucosa of the third gastric compartment (C3), extramedullary hematopoiesis in both the liver and spleen, and the presence of nematodes in C3. Our study emphasizes the importance of H. contortus diagnosis and herd monitoring in New World camelids, particularly llamas.
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX (Edwards)Departments of Pathology (Garner, Sakamoto), College of Veterinary Medicine, The University of Georgia, Athens, GALarge Animal Medicine and Surgery (Williamson), College of Veterinary Medicine, The University of Georgia, Athens, GAInfectious Diseases (Storey), College of Veterinary Medicine, The University of Georgia, Athens, GA.
authors.forename: Erin E
authors.initials: EE
authors.lastname: Edwards
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX (Edwards)Departments of Pathology (Garner, Sakamoto), College of Veterinary Medicine, The University of Georgia, Athens, GALarge Animal Medicine and Surgery (Williamson), College of Veterinary Medicine, The University of Georgia, Athens, GAInfectious Diseases (Storey), College of Veterinary Medicine, The University of Georgia, Athens, GA.
authors.forename: Bridget C
authors.initials: BC
authors.lastname: Garner
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX (Edwards)Departments of Pathology (Garner, Sakamoto), College of Veterinary Medicine, The University of Georgia, Athens, GALarge Animal Medicine and Surgery (Williamson), College of Veterinary Medicine, The University of Georgia, Athens, GAInfectious Diseases (Storey), College of Veterinary Medicine, The University of Georgia, Athens, GA.
authors.forename: Lisa H
authors.initials: LH
authors.lastname: Williamson
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX (Edwards)Departments of Pathology (Garner, Sakamoto), College of Veterinary Medicine, The University of Georgia, Athens, GALarge Animal Medicine and Surgery (Williamson), College of Veterinary Medicine, The University of Georgia, Athens, GAInfectious Diseases (Storey), College of Veterinary Medicine, The University of Georgia, Athens, GA.
authors.forename: Bob E
authors.initials: BE
authors.lastname: Storey
authors.affiliation: Department of Veterinary Pathobiology, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX (Edwards)Departments of Pathology (Garner, Sakamoto), College of Veterinary Medicine, The University of Georgia, Athens, GALarge Animal Medicine and Surgery (Williamson), College of Veterinary Medicine, The University of Georgia, Athens, GAInfectious Diseases (Storey), College of Veterinary Medicine, The University of Georgia, Athens, GA kaoris@uga.edu.
authors.forename: Kaori
authors.initials: K
authors.lastname: Sakamoto
mesh_terms: D000818:Animals; D001344:Autopsy / Q000662:veterinary; D002161:Camelids, New World / Q000469:parasitology*; D005243:Feces / Q000469:parasitology; D006188:Haemonchiasis / Q000473:pathology / Q000662:veterinary*; D006189:Haemonchus / Q000302:isolation & purification*; D012189:Retrospective Studies; D015144:Southeastern United States
keywords: Alpacas; Haemonchus contortus; anemia; camelids; clinical pathology; llamas; nematodes