title: Three new oxazoline alkaloids from Gymnotheca chinensis.
abstract: Three novel oxazoline alkaloids, 1-oxa-3-azaspiro [4.5] dec-2-ene-8-one (1), 1-oxa-3-azaspiro [4.5] dec-2, 6-diene-8-one (2), and 1-oxa-3-azaspiro [4.5] dec-10-methoxy-2, 6-diene-8-one (3) were isolated from the methanol extract of the whole plant of Gymnotheca chinensis. The chemical structures were established by means of spectroscopic analysis including one- and two-dimensional NMR spectroscopy.
authors.affiliation: a School of Pharmacy , Zunyi Medical Universty , Zunyi 563000 , China.
authors.forename: Shi-Ji
authors.initials: SJ
authors.lastname: Xiao
authors.affiliation: b Chengdu Institute of Biology , Chinese Academy of Sciences , Chengdu 610041 , China.
authors.forename: Da-Le
authors.initials: DL
authors.lastname: Guo
authors.affiliation: a School of Pharmacy , Zunyi Medical Universty , Zunyi 563000 , China.
authors.forename: Mao-Sheng
authors.initials: MS
authors.lastname: Zhang
authors.affiliation: c College of Life Science , Sichuan University , Chengdu 610041 , China.
authors.forename: Fang
authors.initials: F
authors.lastname: Chen
authors.affiliation: b Chengdu Institute of Biology , Chinese Academy of Sciences , Chengdu 610041 , China.
authors.forename: Li-Sheng
authors.initials: LS
authors.lastname: Ding
authors.affiliation: b Chengdu Institute of Biology , Chinese Academy of Sciences , Chengdu 610041 , China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D010080:Oxazoles / Q000737:chemistry / Q000302:isolation & purification*; D032134:Saururaceae / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry / Q000302:isolation & purification*; D013237:Stereoisomerism
chemical_list: C000613127:1-oxa-3-azaspiro(4.5)dec-10-methoxy-2,6-diene-8-one; C000613126:1-oxa-3-azaspiro(4.5)dec-2,6-diene-8-one; C000613125:1-oxa-3-azaspiro(4.5)dec-2-ene-8-one; D000470:Alkaloids; D010080:Oxazoles; D013141:Spiro Compounds
keywords: Gymnotheca chinensis; Saururaceae; alkaloid; oxazoline; spiro compound