title: SnapShot: Key Advances in hiPSC Disease Modeling.
abstract: This SnapShot presents a timeline of key advances in directed differentiation and disease modeling using human pluripotent stem cells. The selected papers are color-coded for different systems and show progress in the field, from making disease- and tissue-specific hiPSC derivatives to the development of disease models for drug screening and therapeutics and the generation of complex systems that mimic tissue architecture and self-organized structures. To view this SnapShot, open or download the PDF.
authors.affiliation: Department of Anatomy and Embryology, Leiden University Medical Centre, Einthovenweg 20, 2333ZC Leiden, The Netherlands.
authors.forename: Valeria
authors.initials: V
authors.lastname: Orlova
authors.affiliation: Department of Anatomy and Embryology, Leiden University Medical Centre, Einthovenweg 20, 2333ZC Leiden, The Netherlands.
authors.forename: Christine
authors.initials: C
authors.lastname: Mummery
mesh_terms: D035843:Biomedical Research / Q000266:history; D049674:History, 21st Century; D006801:Humans; D057026:Induced Pluripotent Stem Cells / Q000166:cytology / Q000378:metabolism; D008954:Models, Biological