title: Effect of low-level laser therapy on tooth sensitivity induced by in-office bleaching.
abstract: This study aimed to investigate the effect of low-level laser therapy (LLLT) on tooth sensitivity induced by in-office bleaching. Sixty-six patients enrolled in this randomized clinical trial. Following the in-office procedure with 40% hydrogen peroxide, the participants were randomly divided into three groups. The patients in group 1 received irradiation from a low-level red laser (LLRL; 660 nm, 200 mW, 15 s, 12 J/cm(2)), whereas participants in group 2 were subjected to a low-level infrared laser (LLIL; 810 nm) under similar conditions as in group 1. In group 3 (placebo), the laser treatment was the same as that in groups 1 and 2, but without energy output. The degree of tooth sensitivity was recorded at 1, 24, and 48 h after bleaching using a visual analog scale (VAS). The change in tooth shade was measured 30 days after tooth whitening. The intensity of tooth sensitivity was not significantly different between groups at 1 h after bleaching (p > 0.05). At 24 h after therapy, pain level was significantly lower in the LLIL group compared to the LLRL and placebo groups (p < 0.05). At 48 h after bleaching, VAS scores in the LLIL and LLRL groups were comparable to each other (p > 0.05) and both were significantly lower than that of the placebo group (p < 0.05). There was no significant difference in the efficacy of tooth whitening among groups (p > 0.05). LLLT with an infrared diode laser could be recommended as a suitable strategy to reduce the intensity of tooth sensitivity after in-office bleaching.
authors.affiliation: Dental Materials Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Horieh
authors.initials: H
authors.lastname: Moosavi
authors.affiliation: School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Nooshin
authors.initials: N
authors.lastname: Arjmand
authors.affiliation: Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran. Farzaneh.Ahrari@gmail.com.
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Ahrari
authors.affiliation: Private Practice, Mashhad, Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Zakeri
authors.affiliation: Dental Research Center, School of Dentistry, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Maleknejad
mesh_terms: D000328:Adult; D003807:Dentin Sensitivity / Q000209:etiology / Q000532:radiotherapy*; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D006861:Hydrogen Peroxide / Q000009:adverse effects; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D028022:Low-Level Light Therapy; D008297:Male; D010147:Pain Measurement; D014070:Tooth / Q000187:drug effects / Q000503:physiopathology / Q000528:radiation effects; D014073:Tooth Bleaching / Q000009:adverse effects*; D058205:Tooth Bleaching Agents / Q000009:adverse effects; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D058205:Tooth Bleaching Agents; D006861:Hydrogen Peroxide
keywords: Bleaching; Hydrogen peroxide; In-office bleaching; Low-level laser; Low-power laser; Pain; Therapy; Tooth sensitivity