title: Primary hypertrophic osteoarthropathy: ultrasound and MRI findings.
abstract: Primary hypertrophic osteoarthropathy is a rare genetic disorder related to failures in prostaglandin metabolism. Patients present with joint pain, limb enlargement, skin thickening and finger clubbing. Radiographs show characteristic periosteal reaction and thickening along the long bones. We present MRI and US findings in a child with the condition. Ultrasound showed echogenic tissue surrounding the long bones, presumably reflecting oedema and inflammatory tissue. Doppler sonograms demonstrated increased vascularity on the surface of some superficial bony structures.
authors.affiliation: Clarendon Wing Radiology Department, Leeds Children's Hospital at The Leeds General Infirmary, Belmont Grove, Leeds, West Yorkshire, UK, LS2 9NS.
authors.forename: Brook
authors.initials: B
authors.lastname: Adams
authors.affiliation: Department of Paediatric Rheumatology, Leeds Children's Hospital at The Leeds General Infirmary, Leeds, UK, LS2 9NS.
authors.forename: Tania
authors.initials: T
authors.lastname: Amin
authors.affiliation: Department of Paediatric Rheumatology, Leeds Children's Hospital at The Leeds General Infirmary, Leeds, UK, LS2 9NS.
authors.forename: Valentina
authors.initials: V
authors.lastname: Leone
authors.affiliation: Department of Paediatric Rheumatology, Leeds Children's Hospital at The Leeds General Infirmary, Leeds, UK, LS2 9NS.
authors.forename: Mark
authors.initials: M
authors.lastname: Wood
authors.affiliation: Clarendon Wing Radiology Department, Leeds Children's Hospital at The Leeds General Infirmary, Belmont Grove, Leeds, West Yorkshire, UK, LS2 9NS. Jeannette.Kraft@nhs.net.
authors.forename: Jeannette K
authors.initials: JK
authors.lastname: Kraft
mesh_terms: D002675:Child, Preschool; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D010004:Osteoarthropathy, Primary Hypertrophic / Q000000981:diagnostic imaging* / Q000473:pathology; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D018608:Ultrasonography, Doppler / Q000379:methods*
keywords: Child; Magnetic resonance imaging; Pachydermoperiostosis; Periostitis; Primary hypertrophic osteoarthropathy; Ultrasound