title: Gastrostomy Complications in Pediatric Cancer Patients: A Retrospective Single-Institution Review.
abstract: Complications in pediatric cancer patients after a gastrostomy (GT) placement have not been widely investigated. We aimed to evaluate the complication rate and nature of complications in this specific population.
  
  
  
  Medical records of pediatric cancer patients having a GT placed at our institution from 1998 to 2013 were retrospectively reviewed. Variables analyzed included gender, age, diagnosis, surgical procedure, GT device, duration of GT usage, absolute neutrophil count (ANC) level at surgery, and complications.
  
  
  
  One hundred seventy-one patients (92 males, 79 females), median age of 6 years (range, 0.2-21), who underwent 181 procedures (110 open, 59 endoscopic, and 12 laparoscopic) were identified. Diagnosis included central nervous system tumor (n = 101), solid tumor (n = 45), and leukemia/lymphoma (n = 25). A GT tube was used in 139 procedures and a GT button in 42. Median ANC level at procedure was 3,300/mm(3) (range, 0-38,988). Median duration of GT usage was 8 months (range, 0.2-142). One hundred seventy-seven complications occurred in 106 patients (61.9%) and were categorized as perioperative (<1 month after surgery, 20.3%) and late (>1 month after surgery, 79.7%). Major complications included 42 (23.7%) GT site infections and four (2.2%) intrabdominal complications. The most common minor complication was granulation tissue (28.8%). Younger age at procedure was associated with complications (P = 0.048) and an open technique was associated with GT site infection (P = 0.003). No statistical significance was observed between complications and gender, diagnosis, GT device, duration of GT usage, and ANC at procedure.
  
  
  
  Younger patients were more likely to have complications, and GT site infections were more common after open GT procedures.
authors.affiliation: Department of Surgery, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Israel
authors.initials: I
authors.lastname: Fernandez-Pineda
authors.affiliation: Department of Surgery, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: John A
authors.initials: JA
authors.lastname: Sandoval
authors.affiliation: Department of Surgery, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Reagan M
authors.initials: RM
authors.lastname: Jones
authors.affiliation: Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Nana
authors.initials: N
authors.lastname: Boateng
authors.affiliation: Department of Biostatistics, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Jianrong
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Surgery, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Bhaskar N
authors.initials: BN
authors.lastname: Rao
authors.affiliation: Department of Surgery, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Davidoff
authors.affiliation: Department of Surgery, St Jude Children's Research Hospital, Memphis, Tennessee.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Shochat
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D005260:Female; D005774:Gastrostomy / Q000009:adverse effects*; D006801:Humans; D007223:Infant; D008297:Male; D009369:Neoplasms / Q000453:epidemiology* / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D013997:Time Factors
keywords: complications; gastrostomy; pediatric oncology