title: Carcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland with Epithelial-Myoepithelial Carcinoma Histologic Type.
abstract: A 53-year-old woman presented with a 1-month history of decreased vision and progressive left periorbital fullness. Exam and radiography confirmed a left lacrimal gland mass causing mass effect on the globe and a compressive optic neuropathy. Orbitotomy with excisional biopsy confirmed carcinoma ex pleomorphic adenoma with epithelial and myoepithelial differentiation. Following a negative systemic workup, the patient underwent radiation therapy and remains free of clinical or radiographic disease 24 months following surgery. Herein the presentation, radiography, histopathology, and treatment outcome of a rare case of lacrimal gland epithelial-myoepithelial carcinoma ex pleomorphic adenoma is described.
authors.affiliation: *Department of Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York; and †Memorial Sloan Kettering Cancer Center, New York, New York, U.S.A.
authors.forename: Ema
authors.initials: E
authors.lastname: Avdagic
authors.forename: Nicholas
authors.initials: N
authors.lastname: Farber
authors.forename: Nora
authors.initials: N
authors.lastname: Katabi
authors.forename: Roman
authors.initials: R
authors.lastname: Shinder
mesh_terms: D018262:Adenocarcinoma, Clear Cell / Q000175:diagnosis*; D008949:Adenoma, Pleomorphic / Q000175:diagnosis*; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007765:Lacrimal Apparatus / Q000000981:diagnostic imaging*; D007766:Lacrimal Apparatus Diseases / Q000175:diagnosis*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009378:Neoplasms, Multiple Primary; D014057:Tomography, X-Ray Computed