title: [POSSIBLE CAUSES OF INEFFICIENT MONOTHERAPY OF SUBCLINICAL HYPOTHYROIDISM WITH L-THYROXIN].
abstract: Substitution therapy with L-thyroxin was recognized in 2012 to be the method of choice for the treatment of subclinical hypothyroidism. However it does not always allow to achieve normalization of all metabolic parameters. The aim of our work was to search for and analyze data on the possible mechanisms responsible for the failure of replacement hormonal therapy with L-thyroxin with a view to changing the therapeutic strategy for patients with subclinical hypothyroidism.
authors.forename: A V
authors.initials: AV
authors.lastname: Budnevsky
authors.forename: A Ya
authors.initials: AY
authors.lastname: Kravchenko
authors.forename: E S
authors.initials: ES
authors.lastname: Drobysheva
authors.forename: A A
authors.initials: AA
authors.lastname: Fes'kova
mesh_terms: D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000188:drug therapy*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000627:therapeutic use*
chemical_list: D013972:Thyrotropin; D013974:Thyroxine