title: Validation of the Spanish-language version of the Relevant Outcome Scale for Alzheimer's Disease.
abstract: OBJECTIVE
  The Relevant Outcome Scale for Alzheimer's Disease (ROSA) is a useful tool for evaluating and monitoring dementia patients. This study aims to evaluate the validity and reliability of the Spanish version of ROSA.
  
  
  METHODS
  Spanish multicentre study involving 39 researchers and including 237 patients with Alzheimer disease (78 mild, 79 moderate, and 80 severe). The patients were tested with the following: Mini-Mental State Examination (MMSE), Fototest, Neuropsychiatric Inventory (NPI), Blessed dementia scale, and a Spanish-language version of ROSA. A subsample of 40 subjects was retested in the 14 days following the initial evaluation. The construct validity was evaluated with the Spearman correlation coefficient (r), internal consistency with Cronbach's alpha (alpha), and test-retest reliability with the intraclass correlation coefficient (ICC).
  
  
  RESULTS
  ROSA requires 13.8±7.4minutes to administer and its results show a significant association with the clinical stage of AD (mild, 116.7±23.1; moderate, 92.9±19.8; and severe, 64.3±22.6), and with results on the MMSE (r=0.68), Fototest (r=0.63), NPI (r=0.53), and Blessed dementia scale (r=-0.80). ROSA shows high internal consistency (alpha=0.90) and excellent test-retest reliability (ICC0.97).
  
  
  CONCLUSIONS
  The Spanish version of ROSA is a brief, valid, and reliable tool permitting overall evaluation of patients with dementia.
authors.affiliation: Servicio de Neurología, Hospital Universitario Virgen de las Nieves, Granada, España; Servicio de Neurología, FIDYAN Neurocenter, Granada, España. Electronic address: ccarnero@neurocenter.es.
authors.forename: C
authors.initials: C
authors.lastname: Carnero Pardo
authors.affiliation: Servicio de Neurología, Hospital Universitario Virgen de las Nieves, Granada, España; Servicio de Neurología, FIDYAN Neurocenter, Granada, España.
authors.forename: S
authors.initials: S
authors.lastname: López Alcalde
authors.affiliation: Servicio de Neurología, Hospital Universitario Virgen de las Nieves, Granada, España; Servicio de Neurología, FIDYAN Neurocenter, Granada, España.
authors.forename: M
authors.initials: M
authors.lastname: Espinosa García
authors.affiliation: Departamento Médico, Laboratorios Grunenthal Pharma S.A., Madrid, España.
authors.forename: I
authors.initials: I
authors.lastname: Sánchez Magro
mesh_terms: D000368:Aged; D000544:Alzheimer Disease / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D015203:Reproducibility of Results; D012720:Severity of Illness Index; D013030:Spain; D014175:Translating
keywords: Alzheimer disease; Demencia; Dementia; Enfermedad de Alzheimer; Escala ROSA; Fiabilidad; ROSA scale; Reliability; Validez; Validity