title: Treatment of refractory ulcerative necrobiosis lipoidica diabeticorum with oral thalidomide.
abstract: Ulcerative necrobiosis lipoidica (NL) in diabetic patients is a rare, painful condition. It is a difficult-to-treat condition, impairing quality of life of patients. Although various drugs have been tried, none of them is consistently effective. Biologics in the form of TNF-alpha inhibitors show promising results in the treatment. But because of their high cost we chose thalidomide, which also has TNF-alpha inhibiting properties to successfully treat a long-standing case of ulcerative NL, which was refractory to various treatment modalities.
authors.affiliation: Department of Dermatology and Venereology, Ashvini Rural Medical College, Solapur, Maharashtra, India.
authors.forename: Swapnil D
authors.initials: SD
authors.lastname: Shah
authors.affiliation: Department of Dermatology and Venereology, Ashvini Rural Medical College, Solapur, Maharashtra, India.
authors.forename: Girish V
authors.initials: GV
authors.lastname: Kale
keywords: Diabetes; necrobiosis lipoidica; thalidomide; ulcerative necrobiosis lipoidica