title: Evaluation of Score for Neonatal Acute Physiology and Perinatal Extension II and Clinical Risk Index for Babies with additional parameters.
abstract: BACKGROUND
  The aim of this study was to determine mortality risk by calculating Score for Neonatal Acute Physiology and Perinatal Extension II (SNAP-PE-II) and Clinical Risk Index for Babies (CRIB) score, and evaluate prediction of the effects of antenatal corticosteroid and surfactant treatment on mortality.
  
  
  METHODS
  This multicenter study was conducted simultaneously in five different centers in four different provinces in Southern Turkey between July 2012 and July 2013. A total of 1668 inborn subjects hospitalized in the neonatal intensive care unit within the first 12 h of delivery, and meeting the selection criteria, were included in the study, and CRIB and SNAP-PE-II were used to determine mortality.
  
  
  RESULTS
  The SNAP-PE-II scoring system was applied to all patients, and the CRIB scoring system was used for 310 newborns with gestational age <32 weeks and weighing <1500 g. Of the 1668 patients, 188 died (mortality rate, 11.3%). Cut-off was found to vary with center, which changed specificity and sensitivity of the mortality scores. SNAP-PE-II significantly predicted mortality (P < 0.05) compared with CRIB. SNAP-PE-II also successfully predicted mortality in the group receiving antenatal corticosteroid compared with the group not receiving antenatal corticosteroid.
  
  
  CONCLUSIONS
  SNAP-PE-II was a significant predictor of mortality in newborns with birthweight <1500 g compared with CRIB, and assessment of antenatal corticosteroid use in conjunction with SNAP-PE-II increased the accuracy of the prediction of mortality.
authors.affiliation: Department of Pediatrics, Division of Neonatology, Çukurova University, Adana, Turkey.
authors.forename: Hüseyin Selim
authors.initials: HS
authors.lastname: Asker
authors.affiliation: Department of Pediatrics, Division of Neonatology, Çukurova University, Adana, Turkey. msatar@cu.edu.tr.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Satar
authors.affiliation: Department of Pediatrics, Division of Neonatology, Çukurova University, Adana, Turkey.
authors.forename: Hacer Yapıcıoğlu
authors.initials: HY
authors.lastname: Yıldızdaş
authors.affiliation: Neonatal Intensive Care Unit, Diyarbakır Children's Hospital, Diyarbakır, Turkey.
authors.forename: Birgül
authors.initials: B
authors.lastname: Mutlu
authors.affiliation: Neonatal Intensive Care Unit, Diyarbakır Children's Hospital, Diyarbakır, Turkey.
authors.forename: Banu Mutlu
authors.initials: BM
authors.lastname: Özyurt
authors.affiliation: Neonatal Intensive Care Unit, Diyarbakır Children's Hospital, Diyarbakır, Turkey.
authors.forename: Mehmet Şah
authors.initials: MŞ
authors.lastname: İpek
authors.affiliation: Department of Pediatrics, Division of Neonatology, Gaziantep University, Gaziantep, Turkey.
authors.forename: Ercan
authors.initials: E
authors.lastname: Sivaslı
authors.affiliation: Department of Pediatrics, Division of Neonatology, Gaziantep University, Gaziantep, Turkey.
authors.forename: Şafak
authors.initials: Ş
authors.lastname: Taviloğlu
authors.affiliation: Department of Pediatrics, Division of Neonatology, Mersin University, Mersin, Turkey.
authors.forename: Yalçın
authors.initials: Y
authors.lastname: Çelik
authors.affiliation: Neonatal Intensive Care Unit, Güney Adana Hospital, Adana, Turkey.
authors.forename: Kenan
authors.initials: K
authors.lastname: Özcan
authors.affiliation: Department of Biostatistics, Çukurova University, Adana, Turkey.
authors.forename: Refik
authors.initials: R
authors.lastname: Burgut
authors.affiliation: Department of Biostatistics, Çukurova University, Adana, Turkey.
authors.forename: İlker
authors.initials: İ
authors.lastname: Ünal
mesh_terms: D001724:Birth Weight; D000013:Congenital Abnormalities / Q000175:diagnosis* / Q000401:mortality; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007226:Infant Mortality / Q000639:trends; D007231:Infant, Newborn; D019102:Infant, Very Low Birth Weight; D007363:Intensive Care Units, Neonatal; D008297:Male; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D012720:Severity of Illness Index; D014421:Turkey / Q000453:epidemiology
keywords: SNAP-PE-II; antenatal corticosteroid; neonatal intensive care unit; neonatal mortality