title: Innovations in Small-Animal PET/MR Imaging Instrumentation.
abstract: Multimodal imaging has led to a more detailed exploration of different physiologic processes with integrated PET/MR imaging being the most recent entry. Although the clinical need is still questioned, it is well recognized that it represents one of the most active and promising fields of medical imaging research in terms of software and hardware. The hardware developments have moved from small detector components to high-performance PET inserts and new concepts in full systems. Conversely, the software focuses on the efficient performance of necessary corrections without the use of CT data. The most recent developments in both directions are reviewed.
authors.affiliation: Division of Biomedical Imaging, Faculty of Medicine and Health, University of Leeds, 8.001a, Worsley Building, Clarendon Way, Leeds LS2 9JT, UK.
authors.forename: Charalampos
authors.initials: C
authors.lastname: Tsoumpas
authors.affiliation: LaTIM UMR 1101, INSERM, University of Brest, Bat 1, 1er etage, 5 avenue Foch, Brest 29609, France.
authors.forename: Dimitris
authors.initials: D
authors.lastname: Visvikis
authors.affiliation: Department of Biomedical Engineering, Technological Educational Institute of Athens, Ag. Spiridonos 28, Egaleo, Athens 12210, Greece. Electronic address: gloudos@teiath.gr.
authors.forename: George
authors.initials: G
authors.lastname: Loudos
mesh_terms: D000818:Animals; D000830:Animals, Laboratory; D004583:Electrons; D004867:Equipment Design; D007091:Image Processing, Computer-Assisted; D062069:Inventions / Q000639:trends; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods / Q000639:trends*; D009068:Movement; D064847:Multimodal Imaging / Q000295:instrumentation / Q000379:methods / Q000639:trends*; D049268:Positron-Emission Tomography / Q000295:instrumentation / Q000379:methods / Q000639:trends*; D011829:Radiation Dosage; D012542:Scattering, Radiation; D012984:Software
keywords: Attenuation correction; Input function; Kinetic modeling; Low dose; Motion correction; PET/MR imaging; Silicon photomultiplier; Time of flight