title: [Neuromyelitis optica spectrum disorders as initial presentation of Sjögren's syndrome: A case report].
abstract: Neuromyelitis Optica Spectrum Disorder (NMOSD) is a rare systemic autoimmune disease which is sometimes found in association with other autoimmune disorders including Sjogren's syndrome. Neurological manifestations occur in 20% to 25% of diagnosed cases of Sjögren's syndrome; however, less than 5% of patients with Sjögren's syndrome have neurological manifestations as the initial presenting feature of Sjögren's syndrome. We report the case of an elderly female with longitudinal myelitis as a presenting feature who had positive antibody to aquaporin-4 (NMO-IgG) and Sjögren's syndrome.
authors.affiliation: Servicio de Neurología, Departamento de Medicina, Hospital Daniel Alcides Carrión, Callao, Perú; Unidad de Post Grado, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú; Red de Eficacia Clínica y Sanitaria, REDECS, Lima, Perú. Address: Red de Eficacia Clínica y Sanitaria, Urbanización Principal 396, Distrito Surquillo, Lima, Perú. Email: carlos.alexander.alva@gmail.com.
authors.forename: Carlos
authors.initials: C
authors.lastname: Alva Díaz
authors.affiliation: Servicio de Neurología, Departamento de Medicina, Hospital Daniel Alcides Carrión, Callao, Perú; Unidad de Post Grado, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
authors.forename: Luis
authors.initials: L
authors.lastname: Andamayo Villalba
authors.affiliation: Servicio de Neurología, Departamento de Medicina, Hospital Daniel Alcides Carrión, Callao, Perú; U.S. Naval Medical Research Unit 6, Lima, Perú
authors.forename: Nicanor
authors.initials: N
authors.lastname: Mori
authors.affiliation: Servicio de Neurología, Departamento de Medicina, Hospital Daniel Alcides Carrión, Callao, Perú; Unidad de Post Grado, Facultad de Medicina, Universidad Nacional Mayor de San Marcos, Lima, Perú
authors.forename: Jésica Janet
authors.initials: JJ
authors.lastname: Ventura Chilón
authors.affiliation: Servicio de Neurología, Departamento de Medicina, Hospital Daniel Alcides Carrión, Callao, Perú
authors.forename: Roberto
authors.initials: R
authors.lastname: Romero
mesh_terms: D000368:Aged; D051401:Aquaporin 4 / Q000276:immunology*; D001323:Autoantibodies / Q000276:immunology; D005260:Female; D006801:Humans; D009188:Myelitis, Transverse / Q000209:etiology / Q000276:immunology; D009471:Neuromyelitis Optica / Q000209:etiology* / Q000276:immunology; D012859:Sjogren's Syndrome / Q000175:diagnosis* / Q000276:immunology / Q000503:physiopathology
chemical_list: D051401:Aquaporin 4; D001323:Autoantibodies
keywords: Sjögren's syndrome; neuromyelitis optica spectrum disorders