title: A comparative evaluation of freeze-dried bone allograft with and without bioabsorbable guided tissue regeneration membrane Healiguide(®) in the treatment of Grade II furcation defects: A clinical study.
abstract: BACKGROUND
  Furcation defects represent one of the most demanding therapeutic challenges for periodontal therapy. Various treatment modalities have been tried with different success rates. The present study was undertaken to evaluate the efficacy of freeze-dried bone allograft (FDBA) with and without bioabsorbable guided tissue regeneration (GTR) membrane Healiguide(®) in the treatment of Grade II furcation defects.
  
  
  METHODS
  Ten patients with bilateral Grade II furcation defects were selected for the study. After phase I therapy, subjects were divided into two arms and treated in a split-mouth design. Ten defects were treated with FDBA alone in the control arm. Ten defects were treated with FDBA in conjunction with bioabsorbable GTR membrane Healiguide(®) in test arm. Clinical parameters like plaque index, gingival index, vertical probing depth, horizontal probing depth, and relative attachment level (RAL) were assessed at baseline, 3 months, and 6 months postoperatively.
  
  
  RESULTS
  At 6 months, clinical improvement was seen in both the arms with mean pocket depth reduction of 1.2 ± 1.032 mm and 1.7 ± 0.948 mm and mean horizontal probing depth reduction being 2.1 ± 1.969 mm and 1.6 ± 1.264 mm in control and test arm, respectively. Both surgical procedures resulted in a statistically significant reduction in vertical and horizontal probing depths.
  
  
  CONCLUSIONS
  Both the arms demonstrated a significant improvement in the probing depth, horizontal furcation depth, and RAL at 6 months postsurgery in the treatment of Grade II furcation defects. However, on the intergroup comparison, there was no statistically significant difference in the results achieved between two arms.
authors.affiliation: Department of Periodontics, Sudha Rustagi College of Dental Sciences and Research, Faridbad, Haryana, India.
authors.forename: Deept
authors.initials: D
authors.lastname: Jain
authors.affiliation: Department of Periodontology, Subharti Dental College and Hospital, Meerut, Uttar Pradesh, India.
authors.forename: Dhruvakumar
authors.initials: D
authors.lastname: Deepa
keywords: Collagen membrane; Grade II furcation defects; freeze-dried bone allograft; guided tissue regeneration