title: Preoperative biomedical risk and depressive symptoms are differently associated with reduced health-related quality of life in patients 1year after cardiac surgery.
abstract: To examine whether preoperative biomedical risk and depressive symptoms were associated with physical and mental components of health-related quality of life (HRQoL) in patients 1year after cardiac surgery.
  
  
  
  Seventy-five patients completed a psychological evaluation, including the Center for Epidemiological Study of Depression scale, the 12-item Short-Form Physical Component Scale (SF-12-PCS) and Mental Component Scale (SF-12-MCS), the Instrumental Activities of Daily Living questionnaire for depressive symptoms and HRQoL, respectively, before surgery and at 1-year follow-up.
  
  
  
  Preoperative depressive symptoms predicted the SF-12-PCS (beta=-.22, P<.05) and SF-12-MCS (beta=-.30, P<.04) scores in patients 1year after cardiac surgery, whereas the European System for Cardiac Operative Risk Evaluation was associated with SF-12-PCS (beta=-.28, P<.02), but not SF-12-MCS (beta=.01, P=.97) scores postoperatively.
  
  
  
  The current findings showed that preoperative depressive symptoms are associated with poor physical and mental components of HRQoL, whereas high biomedical risk predicts reduced physical, but not mental, functioning in patients postoperatively. This study suggests that a preoperative assessment of depressive symptoms in addition to the evaluation of common biomedical risk factors is essential to anticipate which patients are likely to show poor HRQoL after cardiac surgery.
authors.affiliation: Department of General Psychology, University of Padova, Via Venezia, 8-35131, Padova, Italy. Electronic address: elisabetta.patron@gmail.com.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: Patron
authors.affiliation: Department of General Psychology, University of Padova, Via Venezia, 8-35131, Padova, Italy. Electronic address: simone.messerotti@unipd.it.
authors.forename: Simone
authors.initials: S
authors.lastname: Messerotti Benvenuti
authors.affiliation: Department of General Psychology, University of Padova, Via Venezia, 8-35131, Padova, Italy. Electronic address: daniela.palomba@unipd.it.
authors.forename: Daniela
authors.initials: D
authors.lastname: Palomba
mesh_terms: D000368:Aged; D006348:Cardiac Surgical Procedures / Q000523:psychology* / Q000706:statistics & numerical data*; D003863:Depression / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care / Q000706:statistics & numerical data*; D057234:Preoperative Period; D011788:Quality of Life; D012306:Risk
keywords: Cardiac surgery; Depression; EuroSCORE; Health-related quality of life; Outcome assessment