title: BOLD data representing activation and connectivity for rare no-go versus frequent go cues.
abstract: The neural circuitry underlying response control is often studied using go/no-go tasks, in which participants are required to respond as fast as possible to go cues and withhold from responding to no-go stimuli. In the current task, response control was studied using a fully counterbalanced design in which blocks with a low frequency of no-go cues (75% go, 25% no-go) were alternated with blocks with a low frequency of go cues (25% go, 75% no-go); see also "Segregating attention from response control when performing a motor inhibition task: Segregating attention from response control" [1]. We applied a whole brain corrected, paired t-test to the data assessing for regions differentially activated by low frequency no-go cues relative to high frequency go cues. In addition, we conducted a generalized psychophysiological interaction analysis on the data using a right inferior frontal gyrus seed region. This region was identified through the BOLD response t-test and was chosen because right inferior gyrus is highly implicated in response inhibition.
authors.affiliation: National Institutes of Health, United States.
authors.forename: Harma
authors.initials: H
authors.lastname: Meffert
authors.affiliation: National Institutes of Health, United States.
authors.forename: Soonjo
authors.initials: S
authors.lastname: Hwang
authors.affiliation: National Institutes of Health, United States.
authors.forename: Zachary T
authors.initials: ZT
authors.lastname: Nolan
authors.affiliation: National Institutes of Health, United States.
authors.forename: Gang
authors.initials: G
authors.lastname: Chen
authors.affiliation: National Institutes of Health, United States.
authors.forename: James R
authors.initials: JR
authors.lastname: Blair
keywords: Cognitive control; Generalized psychophysiological interactions; Go/No-go; Inhibition; fMRI