title: Metastatic pancreatic cancer presenting as linitis plastica of the stomach.
abstract: Metastatic disease from pancreatic carcinoma involving the stomach is an unusual event, and the pattern of spread in the form of linitis plastica, to our knowledge, has not been reported previously. Local recurrence after curative resection for pancreatic cancer is the most common pattern of disease. We report a case of metastatic pancreatic adenocarcinoma presenting as linitis plastica of the stomach 4 years after curative resection. A 52-year-old man presented with epigastric pain and melaena 4 years after undergoing a Whipple's procedure for a poorly-differentiated pancreatic adenocarcinoma, stage IB; T2N0M0. CT imaging of the abdomen revealed thickening of the gastric wall, and subsequent oesophagogastroduodenoscopy (OGD) revealed diffuse friable erythaematous tissue. The biopsy specimen obtained during the OGD revealed a poorly differentiated adenocarcinoma, with similar appearance to the prior specimen obtained from the pancreas.
authors.affiliation: Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
authors.forename: Shivani
authors.initials: S
authors.lastname: Garg
authors.affiliation: Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
authors.forename: Ramzi
authors.initials: R
authors.lastname: Mulki
authors.affiliation: Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: Sher
mesh_terms: D000230:Adenocarcinoma / Q000556:secondary; D003937:Diagnosis, Differential; D006801:Humans; D008039:Linitis Plastica / Q000473:pathology / Q000556:secondary*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D010190:Pancreatic Neoplasms / Q000473:pathology / Q000556:secondary*; D013270:Stomach / Q000000981:diagnostic imaging* / Q000473:pathology; D013274:Stomach Neoplasms / Q000473:pathology / Q000556:secondary*; D014057:Tomography, X-Ray Computed