title: [Use of hyaluronidase to correct hyaluronic acid injections in aesthetic medicine].
abstract: Hyaluronic acid (HA) is the most commonly used filler in aesthetic medicine. However, overcorrections are frequent even with experienced practitioner. Hyaluronidase is an enzyme that hydrolyzes HA. Hyaluronidase has been recently proposed to correct unsatisfactory results of HA injections in aesthetic medicine (overcorrection, asymmetry, Tyndall effect) and to treat immediate complications such as arterial or venous thrombosis. The objective of this technical note was to summarize the literature data regarding the efficacy, safety and technique of use of hyaluronidase. Hyaluronidase may be responsible for allergies. The practitioner should take this risk and the possible drug interactions into account before using this antidote in order to weigh up the risk/benefit ratio.
authors.affiliation: Cabinet Esthelaser, 15, avenue d'Eylau, 75116 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Lacoste
authors.affiliation: Service de chirurgie maxillo-faciale et de chirurgie plastique, réparatrice et esthétique, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France. Electronic address: Barbara.hersant@gmail.com.
authors.forename: B
authors.initials: B
authors.lastname: Hersant
authors.affiliation: Service de chirurgie maxillo-faciale et de chirurgie plastique, réparatrice et esthétique, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: R
authors.initials: R
authors.lastname: Bosc
authors.affiliation: Service de chirurgie maxillo-faciale et de chirurgie plastique, réparatrice et esthétique, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: W
authors.initials: W
authors.lastname: Noel
authors.affiliation: Service de chirurgie maxillo-faciale et de chirurgie plastique, réparatrice et esthétique, hôpital Henri-Mondor, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
authors.forename: J P
authors.initials: JP
authors.lastname: Meningaud
mesh_terms: D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D006821:Hyaluronoglucosaminidase / Q000627:therapeutic use*; D007049:Iatrogenic Disease; D007267:Injections; D019651:Plastic Surgery Procedures / Q000379:methods*; D012086:Reoperation / Q000009:adverse effects / Q000379:methods*; D013518:Surgery, Plastic / Q000009:adverse effects / Q000379:methods*
chemical_list: D006820:Hyaluronic Acid; D006821:Hyaluronoglucosaminidase
keywords: Acide hyaluronique; Aesthetic medicine; Filler; Hyaluronidase; Hyaluronique acid; Injection; Médecine esthétique; Produit de comblement