title: A vision of KIR variation at super resolution.
abstract: The Ninth Killer Cell Immunoglobulin-Like Receptor (KIR) Workshop was held in Winchester, UK late in the summer of 2015. The extraordinary diversity of KIR and its functional consequences were key themes throughout the meeting. Novel sequencing technologies and new bioinformatics techniques continue to increase our understanding of the genetic diversity and evolution of the KIR; while a deeper understanding of KIR functions, including their specificity for MHC and its peptide ligands, are generating more refined models of their role in disease. Limited to 100 delegates from around the world, this intimate workshop facilitated vigorous discussion, generating new ideas for research in this ever-expanding field.
authors.affiliation: The Pirbright Institute, Pirbright, Woking, Surrey, UK.
authors.forename: John A
authors.initials: JA
authors.lastname: Hammond
authors.affiliation: Cancer and Inflammation Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.|Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, USA.
authors.forename: Mary
authors.initials: M
authors.lastname: Carrington
authors.affiliation: Clinical and Experimental Sciences, University of Southampton, Southampton, UK.
authors.forename: Salim I
authors.initials: SI
authors.lastname: Khakoo
mesh_terms: D000818:Animals; D005075:Biological Evolution; D019295:Computational Biology; D004195:Disease Models, Animal; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D007111:Immunity, Cellular; D007694:Killer Cells, Natural / Q000502:physiology*; D011110:Polymorphism, Genetic; D054340:Receptors, KIR / Q000235:genetics*; D006113:United Kingdom
chemical_list: D054340:Receptors, KIR
keywords: inhibitory/activating receptors; killer cell immunoglobulin-like receptors; natural killer cells