title: Comparisons of Emu Necrotic Femoral Head Micro Structure Repaired in Two Different Methods.
abstract: OBJECTIVE
  To compare emu necrotic femoral head micro structure repaired in two different methods.
  
  
  METHODS
  Fifteen adult emus were divided into 3 groups (all n=5), and the right femoral head was selected to research. The first group was the control group; in the second group, femoral head necrosis was made by cryogen with liquid nitrogen; and in the third group, femoral head necrosis was made by local pure ethanol injection. Right femurs were taken for micro CT examination,then femoral head micro structures were compared among these three groups.
  
  
  RESULTS
  No infection or unexpected death was found in all groups. Compared with normal group, necrotic femoral heads in cryogen group showed that bone mineral density significantly reduced after repaire (P=0.015), trabecular space significantly reduced (P=0.001), bone volume fraction significantly enlarged (P=0.036), bone surface/volume fraction (P=0.032) and trabecular numbers (P=0.002) significantly enlarged; trabecular thickness showed no significant difference (P=0.060). Compared with control group, necrotic femoral heads in ethanol group showed that bone mineral density significantly enlarged after repaire (P=0.001), trabecular thickness (P=0.003) and bone surface/volume fraction (P=0.022) significantly enlarged, trabecular space (P=0.001) and bone volume fraction (P=0.001) significantly reduced; the trabecular numbers showed no significant difference (P=0.143). Compared with ethanol group, necrotic femoral heads in cryogen group showed significant lower bone mineral density after repair (P=0.001), significantly lower bone volume fraction (P=0.001), significantly lower trabecular thickness (P=0.001), significantly higher bone surface/volume fraction (P=0.022) and higher trabecular numbers (P=0.003); the trabecular space showed no significant difference (P=0.398).
  
  
  CONCLUSIONS
  Different repair methods make reconstructed femoral head weight bearing area have different bone structure and bone mineral density, along with different bone trabecular quality.
authors.affiliation: 1. Department of Orthopeadics,Tianjin First Center Hospital,Tianjin 300192,China; 2. Institute of Orthopeadics,Chinese PLA General Hospital,Beijing 100853,China;
authors.forename: Meng
authors.initials: M
authors.lastname: Fan
authors.affiliation: Department of Orthopeadics,Tianjin First Center Hospital,Tianjin 300192,China.
authors.forename: Wen-xue
authors.initials: WX
authors.lastname: Jiang
authors.affiliation: Institute of Orthopeadics,Chinese PLA General Hospital,Beijing 100853,China.
authors.forename: Ai-yuan
authors.initials: AY
authors.lastname: Wang
authors.affiliation: Institute of Orthopeadics,Chinese PLA General Hospital,Beijing 100853,China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Peng
authors.affiliation: Institute of Orthopeadics,Chinese PLA General Hospital,Beijing 100853,China.
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Institute of Orthopeadics,Chinese PLA General Hospital,Beijing 100853,China.
authors.forename: Wen-jing
authors.initials: WJ
authors.lastname: Xu
authors.affiliation: Institute of Orthopeadics,Chinese PLA General Hospital,Beijing 100853,China.
authors.forename: Shi-bi
authors.initials: SB
authors.lastname: Lu
mesh_terms: D000818:Animals; D015519:Bone Density; D020312:Dromaiidae; D000431:Ethanol; D005270:Femur Head; D005271:Femur Head Necrosis
chemical_list: D000431:Ethanol