title: Mindfulness- and Acceptance-based Interventions for Psychosis: A Systematic Review and Meta-analysis.
abstract: BACKGROUND
  Mindfulness- and acceptance-based interventions are increasingly studied as a potential treatment for a variety of mental conditions.
  
  
  OBJECTIVE
  To assess the effects of mindfulness- and acceptance-based interventions on psychotic symptoms and hospitalization in patients with psychosis.
  
  
  METHODS
  MEDLINE/PubMed, Embase, the Cochrane Library, and PsycINFO were screened from inception through April 2015. Randomized controlled trials (RCTs) were analyzed when they assessed psychotic symptoms or hospitalization in patients with psychosis; affect, acceptance, mindfulness, and safety were defined as secondary outcomes.
  
  
  RESULTS
  Eight RCTs with a total of 434 patients comparing mindfulness-based (4 RCTs) or acceptance-based interventions (4 RCTs) to treatment as usual or attention control were included. Six RCTs had low risk of bias. Moderate evidence was found for short-term effects on total psychotic symptoms, positive symptoms, hospitalization rates, duration of hospitalization, and mindfulness and for long-term effects on total psychotic symptoms and duration of hospitalization. No evidence was found for effects on negative symptoms, affect, or acceptance. No serious adverse events were reported.
  
  
  CONCLUSIONS
  Mindfulness- and acceptance-based interventions can be recommended as an additional treatment for patients with psychosis.
authors.affiliation: Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney (Dr Cramer), Australia.
authors.forename: Holger
authors.initials: H
authors.lastname: Cramer
authors.affiliation: Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen, Germany; Australian Research Centre in Complementary and Integrative Medicine, Faculty of Health, University of Technology Sydney (Dr Lauche), Australia.
authors.forename: Romy
authors.initials: R
authors.lastname: Lauche
authors.affiliation: Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen (Haller), Germany.
authors.forename: Heidemarie
authors.initials: H
authors.lastname: Haller
authors.affiliation: Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen (Langhorst), Germany.
authors.forename: Jost
authors.initials: J
authors.lastname: Langhorst
authors.affiliation: Department of Internal and Integrative Medicine, Kliniken Essen-Mitte, Faculty of Medicine, University of Duisburg-Essen, Essen (Dobos), Germany.
authors.forename: Gustav
authors.initials: G
authors.lastname: Dobos
keywords: Psychosis; acceptance; meta-analysis; mindfulness; systematic review