title: [Increased risk of mesothelioma and lung cancer among workers exposed to asbestos who could require an anticipated retirement].
abstract: OBJECTIVE
  to assess the association among malignant pleural mesothelioma (MPM) and lung cancer (LC) among workers who have been exposed to asbestos and have or not have required an anticipated leave from work, a possibility offered by the 1992 law banning asbestos in Italy, in the framework of the health surveillance programmes on going in the Veneto Region (Northern Italy).
  
  
  METHODS
  a cohort of asbestos workers derived from the rosters of selected factories and alive in 1992, followed from 1992 to 2012.MPM cases have been identified through the Regional Mesothelioma Registry, while LC cases through a link with the Regional Cancer Registry, hospital discharges, and death certificates. Risks related to asbestos exposure were calculated by mixed effects Poisson regression model.
  
  
  RESULTS
  the risk of MPM and LC increases at any additional duration of work, up to very high values for long term durations of work for MPM, and up to a three fold increase for LC. Early retirements have been requested by a fraction only in the position of submitting it.
  
  
  CONCLUSIONS
  subjects who have been exposed to asbestos should be the target of a post-occupational surveillance, and further work is suggested to identify subjects at high risk of LC because of smoking habits and more heavy exposure to asbestos, in order to develop programmes for primary and secondary cancer prevention.
authors.affiliation: Registro regionale veneto dei casi di mesotelioma, Servizio prevenzione igiene e sicurezza nei luoghi di lavoro (SPISAL), Azienda ULSS 16, Padova. enzo.merler@sanita.padova.it.
authors.forename: Enzo
authors.initials: E
authors.lastname: Merler
authors.affiliation: Registro regionale veneto dei casi di mesotelioma, Servizio prevenzione igiene e sicurezza nei luoghi di lavoro (SPISAL), Azienda ULSS 16, Padova.|Sistema epidemiologico regionale, Regione Veneto, Padova.
authors.forename: Paolo
authors.initials: P
authors.lastname: Girardi
authors.affiliation: Registro regionale veneto dei casi di mesotelioma, Servizio prevenzione igiene e sicurezza nei luoghi di lavoro (SPISAL), Azienda ULSS 16, Padova.
authors.forename: Chiara
authors.initials: C
authors.lastname: Panato
authors.affiliation: Registro regionale veneto dei casi di mesotelioma, Servizio prevenzione igiene e sicurezza nei luoghi di lavoro (SPISAL), Azienda ULSS 16, Padova.
authors.forename: Vittoria
authors.initials: V
authors.lastname: Bressan
mesh_terms: D001194:Asbestos / Q000009:adverse effects; D006801:Humans; D007558:Italy; D008175:Lung Neoplasms / Q000139:chemically induced; D008654:Mesothelioma / Q000139:chemically induced*; D016273:Occupational Exposure / Q000009:adverse effects; D010997:Pleural Neoplasms / Q000139:chemically induced*; D012179:Retirement
chemical_list: D001194:Asbestos