title: Primary Signet Ring Cell Adenocarcinoma of the Urinary Bladder: A Report of 2 Cases.
abstract: Primary signet ring cell carcinoma of the urinary bladder is a rare and aggressive histologic subtype of adenocarcinoma. In general, this tumor occurs in the middle age, and clinical presentation does not differ from transitional cell carcinomas. The prognosis is often poor, given the advanced stage at diagnosis. To our knowledge, <100 cases of signet ring cell adenocarcinoma of the urinary bladder have been reported. We report 2 cases with bladder linitis plastica primitive, and we draw attention to its pathologic, anatomoclinical, and evolution specificity to optimize its therapeutic management.
authors.affiliation: Department of Medical Oncology, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Wiem
authors.initials: W
authors.lastname: Boukettaya
authors.affiliation: Department of Medical Oncology, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Jihene
authors.initials: J
authors.lastname: Feki
authors.affiliation: Anatomopathology Laboratory, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Slim
authors.initials: S
authors.lastname: Charfi
authors.affiliation: Department of Medical Oncology, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Nabil
authors.initials: N
authors.lastname: Toumi
authors.affiliation: Department of Medical Oncology, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Afef
authors.initials: A
authors.lastname: Khanfir
authors.affiliation: Anatomopathology Laboratory, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Tahia
authors.initials: T
authors.lastname: Boudawara
authors.affiliation: Department of Radiotherapy, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Jamel
authors.initials: J
authors.lastname: Daoud
authors.affiliation: Department of Medical Oncology, CHU Habib Bourguiba, Sfax, Tunisia.
authors.forename: Mounir
authors.initials: M
authors.lastname: Frikha
keywords: Adenocarcinoma; Linitis plastica; Signet ring cell carcinoma; Urinary bladder