title: Copper-Catalyzed Intermolecular Hydroamination of Internal Alkynes with Anilines and Amines.
abstract: The copper-catalyzed regioselective intermolecular hydroamination of the aryl and trifluoromethyl group or electron-withdrawing group substituted internal alkynes with amines has been accomplished. The reaction was effectively catalyzed by the ligand-free Cu(OTf)2 and afforded the intended amine derivatives in good yields after treatment of NaBH3CN.
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Tomoki
authors.initials: T
authors.lastname: Ishikawa
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Taro
authors.initials: T
authors.lastname: Sonehara
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Maki
authors.initials: M
authors.lastname: Minakawa
authors.affiliation: Department of Chemistry, College of Humanities & Sciences, Nihon University , Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.
authors.forename: Motoi
authors.initials: M
authors.lastname: Kawatsura