title: General Anesthesia in a Patient With Urticaria Pigmentosa Referred for Electroconvulsive Therapy.
abstract: Urticaria pigmentosa is a rare disorder characterized by an abnormal systemic proliferation of mast cells. In this condition, various triggers can induce either cutaneous histamine release, resulting in rash, or generalized histamine release, resulting in symptomatic hypotension, syncope, or in its severest form, an anaphylactoid reaction resistant to most resuscitative measures. Many anesthetic agents and adjuncts are known potential triggers, and patients who require surgery or procedures under anesthesia must be managed carefully. In this review, we describe the safe use of general anesthesia for electroconvulsive therapy in a patient with urticaria pigmentosa and discuss the association between psychiatric disorders and mastocytoses.
authors.affiliation: From the Departments of *Psychiatry and †Anesthesiology Icahn School of Medicine at Mount Sinai, New York, NY.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Aloysi
authors.forename: Gabriella M
authors.initials: GM
authors.lastname: Ahle
authors.forename: Emma
authors.initials: E
authors.lastname: Geduldig
authors.forename: Charles H
authors.initials: CH
authors.lastname: Kellner
authors.forename: Ethan O
authors.initials: EO
authors.lastname: Bryson
mesh_terms: D000768:Anesthesia, General / Q000379:methods*; D003866:Depressive Disorder / Q000150:complications / Q000523:psychology; D004565:Electroconvulsive Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D014582:Urticaria Pigmentosa / Q000150:complications* / Q000523:psychology; D055815:Young Adult