title: Mitotic Mysteries: The Case of HP1.
abstract: The role of Heterochromatin Protein-1 (HP1) during mitosis has been controversial. Two recent studies in Science and Developmental Cell, from Tanno et al. (2015) and Abe et al. (2016), suggest that the means of HP1 localization and its function at inner centromeres are altered in cancer cells with chromosomal instability.
authors.affiliation: Cell Division Biology Research Group, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Electronic address: jonathan.higgins@ncl.ac.uk.
authors.forename: Jonathan M G
authors.initials: JM
authors.lastname: Higgins
authors.affiliation: Cell Division Biology Research Group, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4HH, UK.
authors.forename: Lisa
authors.initials: L
authors.lastname: Prendergast
mesh_terms: D063646:Carcinogenesis / Q000378:metabolism*; D018797:Cell Cycle Proteins / Q000378:metabolism*; D002503:Centromere / Q000378:metabolism*; D043171:Chromosomal Instability; D020090:Chromosome Segregation; D006801:Humans
chemical_list: D018797:Cell Cycle Proteins