title: Functionalized Metallated Cavitands via Imidation and Late-Stage Elaboration.
abstract: Efficient methods for the preparation of functionalized metallated cavitands are described. Functional groups can be either introduced by an imidation of metal-oxo complexes or by a late-stage elaboration of the imido ligands. By using diversified iminophosphorane (PPh3=NR) reagents, π-conjugated pyrene, redox active ferrocene and polymerizable norbornene moieties were successfully introduced. Furthermore, the iodo and alkynyl groups on the imido ligands are capable of undergoing efficient Sonogashira cross-coupling and copper-catalyzed azide alkyne cycloaddition reactions, thereby providing facile access to complex architectures containing metallated cavitands.
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA, https://swagergroup.mit.edu/
authors.forename: Yanchuan
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA, https://swagergroup.mit.edu/
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Swager
keywords: calixarene; cavitand; late-stage functionalization; supramolecular