title: Association between individual ovarian dimensions with ovarian reserve indices.
abstract: BACKGROUND
  In some young female candidates of assisted reproductive technology (ART), ovarian response to simulative treatments is less than what is expected. More precise assessment of oocyte quality and quantity through studying ovarian dimensions can be useful for determining the dose of ovarian stimulant drugs and for preventing ART cycles cancellation. The aim of the present study is to determine the association between ovarian dimensions and ovarian reserve (OR) indices and whether ovarian dimensions can predict ovarian reserve.
  
  
  METHODS
  In this cross-sectional study, 85 infertile women were studied. In early follicular phase, ovarian diameters (including length and width of the ovaries) were measured using transvaginal ultrasonography. Mean ovarian diameters (MOD) were calculated according to average length and width of the ovaries. A serum sample was taken from all patients to measure the level of Follicular Stimulating Hormone (FSH) and oestradiol as OR indices.
  
  
  RESULTS
  The results of univariate analysis showed that FSH and oestradiol had a negative significant association with width, length and MOD (P < 0.01). The results of multivariate regression analysis showed that FSH and oestradiol had a negative significant association with width (βFSH = -0.59, P = 0.001 and βOestradiol = -0.019, P = 0.029) and MOD (βFSH = -0.52, P = 0.003 and βOestradiol = -0.021, P = 0.017) and had a borderline negative significant correlation with ovarian length (βFSH = -0.49, P=0.077 and βOestradiol = 0.022, P = 0.08) CONCLUSIONS: The results of this study revealed that despite a moderate correlation, ovarian diameters could be an applicable index for predicting OR. Using this method along with other methods may be useful in treatment with ovarian stimulants.
authors.affiliation: National Board OB & Gynecologist, IVF Unit, Mirza Kouchak Khan Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Elham Hashemian
authors.initials: EH
authors.lastname: Naeini
authors.affiliation: PhD Candidate, Islamic Azad University, Naein Branch, Naein, Iran.
authors.forename: Mohammad Zare
authors.initials: MZ
authors.lastname: Neyestanak
authors.affiliation: Fellowship in Infertility, IVF Unit, Mirza Kouchak Khan Hospital, Tehran, Iran.
authors.forename: Katayon
authors.initials: K
authors.lastname: Berjis
authors.affiliation: Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Iran.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Shokoohi
keywords: FSH; infertility; oestradiol; ovarian length; ovarian width