title: A giant mucinous cystadenocarcinoma of the appendix: a case report and review of the literature.
abstract: BACKGROUND
  Mucinous cystadenocarcinoma is the second most common etiology of appendiceal mucocele. We report a relatively rare case of a giant appendiceal mucocele caused by mucinous cystadenocarcinoma, which occupied the entire abdomen of an adult woman.
  
  
  METHODS
  A 63-year-old woman presented with a chief complaint of abdominal distention. Imaging studies showed a giant cystic mass occupying her entire abdomen. Laparotomy confirmed a giant appendiceal mucocele, and the patient underwent ileocecal resection. A mucinous deposit was not found in her abdominal cavity, and the ovaries were grossly normal bilaterally. The pathological diagnosis was mucinous adenocarcinoma with a low-grade mucinous neoplasm that invaded the subserosa. Regional lymph node metastasis was not found. She has had recurrence-free survival for 5 years.
  
  
  CONCLUSIONS
  The present case is the largest appendiceal cystadenocarcinoma ever reported. The optimal treatment of an appendiceal neoplasm requires further research based on consensus terminology of an appendiceal mucocele.
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. hinagata-tky@umin.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Nagata
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. kondou-ash@umin.org.|Department of Surgery, Kikkoman General Hospital, 100 Miyazaki, Noda-city, Chiba, 278-0005, Japan. kondou-ash@umin.org.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kondo
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. kawaik-sur@h.u-tokyo.ac.jp.
authors.forename: Kazushige
authors.initials: K
authors.lastname: Kawai
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. ishihara-1su@h.u-tokyo.ac.jp.
authors.forename: Soichiro
authors.initials: S
authors.lastname: Ishihara
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. kaz-tky@umin.ac.jp.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Kazama
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. nirei_takako@yahoo.co.jp.|Department of Surgery, Kikkoman General Hospital, 100 Miyazaki, Noda-city, Chiba, 278-0005, Japan. nirei_takako@yahoo.co.jp.
authors.forename: Takako
authors.initials: T
authors.lastname: Nirei
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. dsouma-tky@umin.ac.jp.|Department of Surgery, Kikkoman General Hospital, 100 Miyazaki, Noda-city, Chiba, 278-0005, Japan. dsouma-tky@umin.ac.jp.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Soma
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. jymda-tky@umin.ac.jp.
authors.forename: Jun
authors.initials: J
authors.lastname: Yamada
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. eijisunami@gmail.com.
authors.forename: Eiji
authors.initials: E
authors.lastname: Sunami
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. kitayama-tky@umin.ac.jp.
authors.forename: Joji
authors.initials: J
authors.lastname: Kitayama
authors.affiliation: Department of Surgery, Kikkoman General Hospital, 100 Miyazaki, Noda-city, Chiba, 278-0005, Japan. ykubota@mail.kikkoman.co.jp.
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Kubota
authors.affiliation: Division of Surgical Oncology, Department of Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan. toshwatanabe@yahoo.co.jp.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Watanabe
mesh_terms: D000328:Adult; D001063:Appendiceal Neoplasms / Q000473:pathology* / Q000601:surgery; D018282:Cystadenocarcinoma, Mucinous / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D008875:Middle Aged; D011379:Prognosis