title: Cardiac complications in a metamizole-induced type I Kounis syndrome.
abstract: Kounis syndrome is defined as the coincidental occurrence of allergic reaction and acute coronary syndrome secondary to vasospasm. Anti-inflammatory drugs are included as one of the multiple causes. Current data available about this syndrome come from case reports. We present the case of a patient who suffered Kounis syndrome with cardiogenic shock and asystole after intravenous infusion of Metamizole, and in which no lesions were observed in coronariography.
authors.affiliation: Anesthesiology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain. Electronic address: signalis@hotmail.com.
authors.forename: Jose F Martínez
authors.initials: JF
authors.lastname: Juste
authors.affiliation: Anesthesiology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
authors.forename: Tomas Ruiz
authors.initials: TR
authors.lastname: Garces
authors.affiliation: Anesthesiology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
authors.forename: Rafael Gonzalez
authors.initials: RG
authors.lastname: Enguita
authors.affiliation: Anesthesiology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
authors.forename: Pedro Cia
authors.initials: PC
authors.lastname: Blasco
authors.affiliation: Anesthesiology Department, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain.
authors.forename: Jara Altemir
authors.initials: JA
authors.lastname: Trallero
mesh_terms: D054058:Acute Coronary Syndrome / Q000139:chemically induced*; D000368:Aged; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage / Q000009:adverse effects; D017023:Coronary Angiography / Q000379:methods; D003329:Coronary Vasospasm / Q000139:chemically induced*; D004177:Dipyrone / Q000008:administration & dosage / Q000009:adverse effects*; D004342:Drug Hypersensitivity / Q000209:etiology*; D006801:Humans; D007262:Infusions, Intravenous; D008297:Male; D012770:Shock, Cardiogenic / Q000139:chemically induced; D013577:Syndrome
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D004177:Dipyrone
keywords: Assistolia; Asystole; Cardiogenic shock; Choque cardiogênico; Kounis syndrome; Metamizol; Metamizole; Síndrome de Kounis