title: Prevalence of vitamin D deficiency in mothers and their newborns in a Tunisian population.
abstract: OBJECTIVE
  To assess vitamin D status in mothers and their newborns and identify predictive factors of vitamin D deficiency.
  
  
  METHODS
  A cross-sectional study was undertaken of healthy women and their full-term newborns delivered at the Charles Nicolle Hospital, Tunis, Tunisia, between October and November 2012. Maternal and neonatal serum 25-hydroxy vitamin D (25(OH)D) concentrations were measured. Correlations were tested.
  
  
  RESULTS
  Overall, 87 mothers and their newborns were enrolled. No mother or neonate had an adequate vitamin D status. Mean maternal and neonatal serum 25(OH)D concentrations were 6.82±5.14ng/mL (range 3.60-23.77) and 5.92±4.15ng/mL (range 3.60-22.28), respectively. Vitamin D deficiency (serum 25(OH)D<20ng/mL) was found in 84 (97%) mothers and 85 (98%) neonates, of whom 76 (87%) and 78 (90%), respectively, had severe deficiency (serum 25(OH)D<12ng/mL). Maternal serum 25(OH)D showed a strong positive correlation with neonatal serum 25(OH)D (r=0.69, P<0.001). Maternal dietary vitamin D intake was the only factor shown to be associated with serum 25(OH)D concentrations (P<0.05).
  
  
  CONCLUSIONS
  Vitamin D deficiency is prevalent among Tunisian mothers and their neonates.
authors.affiliation: Department of Neonatology, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia. Electronic address: imen_ayadi@hotmail.com.
authors.forename: Imene D
authors.initials: ID
authors.lastname: Ayadi
authors.affiliation: Department of Neonatology, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Emira B H
authors.initials: EB
authors.lastname: Nouaili
authors.affiliation: Biochemistry Laboratory, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Emna
authors.initials: E
authors.lastname: Talbi
authors.affiliation: Department of Neonatology, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Aicha
authors.initials: A
authors.lastname: Ghdemssi
authors.affiliation: Department of Nutrition, National Institute of Nutrition, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Chiraz
authors.initials: C
authors.lastname: Rached
authors.affiliation: Biochemistry Laboratory, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Afef
authors.initials: A
authors.lastname: Bahlous
authors.affiliation: Department of Nutrition, National Institute of Nutrition, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Amel
authors.initials: A
authors.lastname: Gammoudi
authors.affiliation: Department of Obstetrics and Gynecology, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Sonia Ben
authors.initials: SB
authors.lastname: Hamouda
authors.affiliation: Department of Obstetrics and Gynecology, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Badreddine
authors.initials: B
authors.lastname: Bouguerra
authors.affiliation: Biochemistry Laboratory, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Kehna
authors.initials: K
authors.lastname: Bouzid
authors.affiliation: Biochemistry Laboratory, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Jouda
authors.initials: J
authors.lastname: Abdelmoula
authors.affiliation: Department of Neonatology, Charles Nicolle Hospital, Tunis El Manar University, Tunis, Tunisia.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Marrakchi
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D011247:Pregnancy; D014416:Tunisia / Q000453:epidemiology; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: Deficiency; Newborn; Pregnancy; Vitamin D