title: Autologous Limbal Stem Cell Transplantation: The Progression of Diagnosis and Treatment.
abstract: Though the corneoscleral limbus has been studied for more than 150 years, our ability to successfully treat those with limbal stem cell deficiency (LSCD) is still a work in progress. Today, the only definitive cure for LSCD is stem cell transplantation. This review briefly discusses the evolution of our understanding of limbal stem cell function, provides an outline of the history of autologous limbal stem cell (LSC) transplantation, and discusses current techniques and future strategies for LSCD treatment.
authors.affiliation: a Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School , Boston , Massachusetts , USA.
authors.forename: Haumith
authors.initials: H
authors.lastname: Khan-Farooqi
authors.affiliation: a Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School , Boston , Massachusetts , USA.
authors.forename: James
authors.initials: J
authors.lastname: Chodosh
mesh_terms: D003316:Corneal Diseases / Q000628:therapy*; D006801:Humans; D016850:Limbus Corneae / Q000166:cytology*; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000502:physiology*; D014182:Transplantation, Autologous
keywords: Cornea; epithelium; limbal stem cell deficiency; limbus; transplant