title: A novel voltammetric sensor for citalopram based on multiwall carbon nanotube/(poly(p-aminobenzene sulfonic acid)/β-cyclodextrin).
abstract: Multi-walled carbon nanotube (MWCNTS) coated with poly p-aminobenzene sulfonic acid/β-cyclodextrin (p-ABSA/β-CD) film was used as an effective strategy for modification of the surface of glassy carbon electrode (GCE). Electrochemical study and determination of citalopram (CT) were investigated at the p (p-ABSA)/β-CD/MWCNT/GC using cyclic and differential pulse anodic stripping voltammetric techniques. The results indicate that the p (p-ABSA)/β-CD/MWCNT/GC significantly enhanced the oxidation peak current of CT. The modified electrode was characterized by electrochemical impedance spectroscopy (EIS), scanning electron microscopy(SEM) and cyclic voltammetry (CV).The fabricated electrochemical sensor exhibits a fast and reversible linear response toward CT within the concentration ranges of 90 nM-1 μM, 1-11 μM and 11-100 μM with correlation coefficients greater than 0.99 and detection limit of 44 nM. The resulting functionalized polymer film features interesting electrochemical properties such good recovery, reproducibility and selectivity toward CT. The applicability of the proposed sensor was tested by determination of CT in pharmaceutical combinations and human body fluids.
authors.affiliation: Department of Analytical Chemistry, Razi University, Kermanshah, Iran. Electronic address: mbgholivand2013@gmail.com.
authors.forename: Mohammad-Bagher
authors.initials: MB
authors.lastname: Gholivand
authors.affiliation: Department of Analytical Chemistry, Razi University, Kermanshah, Iran.
authors.forename: Arezoo
authors.initials: A
authors.lastname: Akbari
mesh_terms: D015283:Citalopram / Q000032:analysis*; D055664:Electrochemical Techniques; D006801:Humans; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010084:Oxidation-Reduction; D047392:beta-Cyclodextrins / Q000737:chemistry*
chemical_list: D037742:Nanotubes, Carbon; D047392:beta-Cyclodextrins; D015283:Citalopram
keywords: Citalopram; Modified electrode; Voltammetry; p-Aminobenzene sulfonic acid; β-Cyclodextrin