title: Randomized, Open-Label, Parallel Group Study to Evaluate the Effect of Internet-Based Glucose Management System on Subjects with Diabetes in China.
abstract: Large amounts of time and effort are needed to implement an Internet-based glucose monitoring system (IBGMS) in the clinical setting. This study was designed using research experience that was developed while implementing an IBGMS in Korea, and the research platform was modified to evaluate the efficacy of an IBGMS in controlling blood sugar in the Chinese population.
  
  
  
  A randomized, open-label, parallel group design was used to evaluate the efficacy of an IBGMS among Chinese subjects with type 2 diabetes. Over a 6-month period, 182 subjects were evaluated in the IBGMS (n = 92) or control (n = 90) groups.
  
  
  
  After 3 months, the control group's HbA1c levels were reduced from 8.0% ± 0.8% to 7.3% ± 1.2% (p < 0.001) and the IBGMS group experienced a reduction from 7.9% ± 0.8% to 6.9% ± 0.7% (p < 0.001); the IBGMS group's end value was significantly lower (p = 0.014). The intragroup changes in the control and IBGMS groups were significant at the 3-month (p = 0.002) and 6-month (p < 0.01) follow-ups. Over this period, the HbA1c levels in the control group increased slightly (7.3% ± 1.1% to 7.4% ± 1.3%, p = 0.605), and the HbA1c levels in the IBGMS group decreased slightly (6.9% ± 0.7% to 6.7% ± 0.7%, p = 0.081).
  
  
  
  The IBGMS was effective in improving blood sugar levels among patients with diabetes. Therefore, IBGMS experience can be effectively transferred between institutions and countries.
authors.affiliation: 1 Department of Medical Informatics, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.|2 Department of Endocrinology and Metabolism, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.
authors.forename: Hun-Sung
authors.initials: HS
authors.lastname: Kim
authors.affiliation: 3 Department of Endocrinology and Metabolism, The First Hospital of Jilin University , Changchun, China .
authors.forename: Chenglin
authors.initials: C
authors.lastname: Sun
authors.affiliation: 1 Department of Medical Informatics, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.
authors.forename: So Jung
authors.initials: SJ
authors.lastname: Yang
authors.affiliation: 3 Department of Endocrinology and Metabolism, The First Hospital of Jilin University , Changchun, China .
authors.forename: Lin
authors.initials: L
authors.lastname: Sun
authors.affiliation: 3 Department of Endocrinology and Metabolism, The First Hospital of Jilin University , Changchun, China .
authors.forename: Fei
authors.initials: F
authors.lastname: Li
authors.affiliation: 1 Department of Medical Informatics, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.
authors.forename: In Young
authors.initials: IY
authors.lastname: Choi
authors.affiliation: 2 Department of Endocrinology and Metabolism, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.
authors.forename: Jae-Hyoung
authors.initials: JH
authors.lastname: Cho
authors.affiliation: 3 Department of Endocrinology and Metabolism, The First Hospital of Jilin University , Changchun, China .
authors.forename: Guixia
authors.initials: G
authors.lastname: Wang
authors.affiliation: 1 Department of Medical Informatics, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.|2 Department of Endocrinology and Metabolism, College of Medicine, The Catholic University of Korea , Seoul, Republic of Korea.
authors.forename: Kun-Ho
authors.initials: KH
authors.lastname: Yoon
mesh_terms: D000328:Adult; D015190:Blood Glucose Self-Monitoring / Q000379:methods*; D002681:China; D003924:Diabetes Mellitus, Type 2 / Q000097:blood*; D005260:Female; D006442:Glycated Hemoglobin; D006801:Humans; D020407:Internet; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance / Q000706:statistics & numerical data*; D012648:Self Care
chemical_list: D006442:Glycated Hemoglobin
keywords: Diabetes mellitus; Internet-based glucose monitoring system (IBGMS); mobile health; telehealth