title: A fluorescent surrogate of thymidine in duplex DNA.
abstract: is a new fluorescent thymidine mimic composed of 2'-deoxyuridine fused to dimethylaniline. exhibits the same pKa and base pairing characteristics as native thymidine residues, and its fluorescence properties are highly sensitive to nucleobase ionization, base pairing and metal binding.
authors.affiliation: Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. nathan.luedtke@chem.uzh.ch.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Mata
authors.affiliation: Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. nathan.luedtke@chem.uzh.ch.
authors.forename: Olivia P
authors.initials: OP
authors.lastname: Schmidt
authors.affiliation: Department of Chemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. nathan.luedtke@chem.uzh.ch.
authors.forename: Nathan W
authors.initials: NW
authors.lastname: Luedtke
mesh_terms: D020029:Base Pairing; D004247:DNA / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D008958:Models, Molecular; D018716:Molecular Mimicry; D009691:Nucleic Acid Denaturation; D013696:Temperature; D013936:Thymidine / Q000737:chemistry*
chemical_list: D005456:Fluorescent Dyes; D004247:DNA; D013936:Thymidine