title: An Index Case of Cutaneous Hodgkin Lymphoma and Review of the Literature.
abstract: Hodgkin lymphoma (HL), although a common hematopoietic malignancy, presents as a primary cutaneous form in extraordinarily rare instances. In this study, we present a remarkable case of a 76-year-old woman with a history of bony metastatic breast cancer who developed multiple subcutaneous nodules on the left neck and scalp. A biopsy revealed the histological and immunohistochemical findings of classic HL. She was treated with systemic chemotherapy and quickly achieved disease remission. Five months later, she was alive and without evidence of lymphoma, consistent with our understanding of primary cutaneous HL as an indolent variant of HL.
authors.affiliation: *Department of Dermatology, University of Colorado Anschutz Medical College, Aurora, CO; †Department of Pathology and Laboratory Medicine, Weill Cornell Medical College, New York, NY; ‡Section Dermatopathology, Atlantic Pathology Group, Melbourne, FL.
authors.forename: Giang
authors.initials: G
authors.lastname: Huong
authors.forename: Luke C
authors.initials: LC
authors.lastname: Olson
authors.forename: George E
authors.initials: GE
authors.lastname: Rippis
authors.forename: Cynthia M
authors.initials: CM
authors.lastname: Magro
mesh_terms: D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D005260:Female; D006258:Head and Neck Neoplasms / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D006689:Hodgkin Disease / Q000188:drug therapy / Q000378:metabolism / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D012074:Remission Induction; D012535:Scalp / Q000737:chemistry / Q000473:pathology*; D012878:Skin Neoplasms / Q000737:chemistry / Q000188:drug therapy / Q000473:pathology*; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D014408:Biomarkers, Tumor