title: Percutaneous High-Energy Microwave Ablation for the Treatment of Pulmonary Tumors: A Retrospective Single-Center Experience.
abstract: OBJECTIVE
  To evaluate the safety and efficacy of percutaneous high-energy microwave ablation (MWA) for the treatment for pulmonary tumors.
  
  
  METHODS
  A retrospective review was undertaken of 44 patients (21 men, 23 women; median age, 66 y; range, 17-89 y) who underwent 62 sessions of high-energy MWA for 87 pulmonary tumors at a single tertiary referral center between June 2012 and June 2014. Primary tumor origin was sarcoma (n = 23), colorectal (n = 16), lung (n = 2), esophageal (n = 1), breast (n = 1), and bladder (n = 1). Median tumor size was 12 mm (range, 6-45 mm). Technical success was recorded contemporaneously, complication rate at 30 days was recorded prospectively, and technique effectiveness was assessed by longitudinal follow-up CT scan.
  
  
  RESULTS
  Primary technical success was achieved in 94% of ablation sessions. The median follow-up interval was 15 months (range, 6.2-29.5 mo) during which time local tumor progression was observed in two of 87 tumors (technique effectiveness 98%). Pneumothorax requiring chest tube insertion occurred in 19%; delayed pneumothorax occurred in four patients. No hemoptysis, infection, or other complications were recorded.
  
  
  CONCLUSIONS
  High-energy MWA is safe and effective for the destruction of lung tumors.
authors.affiliation: Interventional Oncology Service, University College London Hospital, London, United Kingdom; Department of Radiology, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan. Electronic address: egashiy2@cc.saga-u.ac.jp.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Egashira
authors.affiliation: Centre for Medical Imaging, University College London, London, United Kingdom.
authors.forename: Saurabh
authors.initials: S
authors.lastname: Singh
authors.affiliation: Centre for Medical Imaging, University College London, London, United Kingdom.
authors.forename: Steve
authors.initials: S
authors.lastname: Bandula
authors.affiliation: Interventional Oncology Service, University College London Hospital, London, United Kingdom.
authors.forename: Rowland
authors.initials: R
authors.lastname: Illing
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008131:London; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D008297:Male; D008872:Microwaves / Q000009:adverse effects / Q000627:therapeutic use*; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D047368:Tumor Burden; D055815:Young Adult