title: Giant kidney worms in a patient with renal cell carcinoma.
abstract: Dioctophyma renale (D. renale), or giant kidney worms, are the largest nematodes that infect mammals. Approximately 20 cases of human infection have been reported. We present a case of a 71-year-old man with a recent history of unintentional weight loss and painless haematuria, passing elongated erythematous tissue via his urethra. CT revealed a left renal mass with pulmonary nodules and hepatic lesions. On microscopy, the erythematous tissue passed was identified as D. renale. On subsequent renal biopsy, pathology was consistent with renal cell carcinoma. This is the first reported case of concomitant D. renale infection and renal cell carcinoma, and the second reported case of D. renale infection of the left kidney alone.
authors.affiliation: Cook County-Loyola Family Medicine Residency Program, Department of Family and Community Medicine, Cook County Health and Hospitals System, Chicago, Illinois, USA.
authors.forename: Jemima
authors.initials: J
authors.lastname: Kuehn
authors.affiliation: Division of Urology, Cook County Health and Hospitals System, Chicago, Illinois, USA.
authors.forename: Lindsay
authors.initials: L
authors.lastname: Lombardo
authors.affiliation: Department of Pathology, Cook County Health and Hospitals System, Chicago, Illinois, USA.
authors.forename: William M
authors.initials: WM
authors.lastname: Janda
authors.affiliation: Division of Urology, Cook County Health and Hospitals System, Chicago, Illinois, USA Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
authors.forename: Courtney M P
authors.initials: CM
authors.lastname: Hollowell
mesh_terms: D000368:Aged; D000818:Animals; D000977:Antiparasitic Agents / Q000627:therapeutic use; D002292:Carcinoma, Renal Cell / Q000150:complications / Q000175:diagnosis*; D017159:Dioctophymatoidea / Q000302:isolation & purification*; D017189:Enoplida Infections / Q000150:complications / Q000175:diagnosis*; D017809:Fatal Outcome; D006417:Hematuria / Q000209:etiology; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D007668:Kidney / Q000469:parasitology*; D008297:Male; D055613:Multiple Pulmonary Nodules / Q000150:complications; D014057:Tomography, X-Ray Computed
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin