title: Xanthones of Lichen Source: A 2016 Update.
abstract: An update of xanthones encountered in lichens is proposed as more than 20 new xanthones have been described since the publication of the compendium of lichen metabolites by Huneck and Yoshimura in 1996. The last decades witnessed major advances regarding the elucidation of biosynthetic schemes leading to these fascinating compounds, accounting for the unique substitution patterns of a very vast majority of lichen xanthones. Besides a comprehensive analysis of the structures of xanthones described in lichens, their bioactivities and the emerging analytical strategies used to pinpoint them within lichens are presented here together with physico-chemical properties (including NMR data) as reported since 1996.
authors.affiliation: Laboratoire de Pharmacognosie, Equipe PNSCM, (ISCR UMR CNRS 6226), Faculté des Sciences Pharmaceutiques et Biologiques, 2 Avenue du Professeur Léon Bernard, 35043, Rennes Cédex, France. pierre.lepogam-alluard@univ-rennes1.fr.
authors.forename: Pierre
authors.initials: P
authors.lastname: Le Pogam
authors.affiliation: Laboratoire de Pharmacognosie, Equipe PNSCM, (ISCR UMR CNRS 6226), Faculté des Sciences Pharmaceutiques et Biologiques, 2 Avenue du Professeur Léon Bernard, 35043, Rennes Cédex, France. joel.boustie@univ-rennes1.fr.
authors.forename: Joël
authors.initials: J
authors.lastname: Boustie
mesh_terms: D055598:Chemical Phenomena; D008011:Lichens / Q000737:chemistry* / Q000378:metabolism / Q000382:microbiology; D009682:Magnetic Resonance Spectroscopy; D015394:Molecular Structure; D013559:Symbiosis; D044004:Xanthones / Q000737:chemistry* / Q000378:metabolism / Q000494:pharmacology
chemical_list: D044004:Xanthones
keywords: NMR spectroscopy; bioactivity; biosynthesis; fungi; islandicin; lichexanthone; polyketides; secalonic acids; thiomelin