title: Pregnancy after oocyte donation in 45, X Turner syndrome women, complicated by gestational diabetes and polyhydramnios. Case report and mini-review of literature.
abstract: Patients suffering from Turner syndrome (TS) demonstrate characteristic clinical features, with a short stature and gonadal dysgenesis causing infertility in most patients. Spontaneous pregnancies in women with TS are quite rare and pregnancy outcomes involving an increased risk of miscarriage and stillbirths are observed. In this case report, we present a 28 years old pregnant woman with the diagnosis of TS. Due to hypergonadotrophic hypogonadism, she was proposed an in vitro fertilization (IVF) program with an oocyte donor from unrelated anonymous women. After the second transfer, implantation occurred. In the 24th week of gestation, gestational diabetes class 1 was diagnosed. In the 31st week of gestation, polyhydramnios was diagnosed, although other parameters were reassuring. Considering the polyhydramnios, along with the diagnosis of Turner syndrome in the mother, we decided to perform an elective cesarean section. Subsequently, a healthy term male was born. For most women with the diagnosis of TS, the only way to become pregnant is through oocyte donation. The aim of this work was to characterize the course of pregnancy in TS patient and review literature addressing this issue.
authors.affiliation: a Department of Gynecological Endocrinology , Poznan University of Medical Sciences , Poznan , Poland.
authors.forename: Adam
authors.initials: A
authors.lastname: Czyzyk
authors.affiliation: a Department of Gynecological Endocrinology , Poznan University of Medical Sciences , Poznan , Poland.
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Podfigurna-Stopa
authors.affiliation: a Department of Gynecological Endocrinology , Poznan University of Medical Sciences , Poznan , Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Katulski
authors.affiliation: b Department of Perinatology and Gynaecology , Poznan University of Medical Sciences , Poznan , Poland , and.
authors.forename: Grzegorz H
authors.initials: GH
authors.lastname: Breborowicz
authors.affiliation: c Department of Reproductive Medicine and Child Development , Division of Gynecology and Obstetrics, University of Pisa , Pisa , Italy.
authors.forename: Andrea R
authors.initials: AR
authors.lastname: Genazzani
authors.affiliation: a Department of Gynecological Endocrinology , Poznan University of Medical Sciences , Poznan , Poland.
authors.forename: Blazej
authors.initials: B
authors.lastname: Meczekalski
mesh_terms: D000328:Adult; D002585:Cesarean Section; D016640:Diabetes, Gestational; D004624:Embryo Transfer; D005260:Female; D006801:Humans; D050498:Live Birth; D018587:Oocyte Donation; D006831:Polyhydramnios / Q000453:epidemiology; D011247:Pregnancy; D014424:Turner Syndrome
keywords: Oocyte donation; Turner syndrome; pregnancy