title: Good's Syndrome Accompanied by Agranulocytosis Following a Rapid Clinical Course.
abstract: Good's syndrome is an immunodeficiency disease involving thymoma accompanied by hypogammaglobulinemia. We encountered a case of Good's syndrome accompanied by agranulocytosis that followed a rapid clinical course. A 72-year-old man visited our hospital with a two-week history of a sore throat. Candida albicans was detected in the pharynx, and hypogammaglobulinemia was detected in addition to granulocytopenia. The patient subsequently developed septic shock and followed a rapid clinical course which ended in death. Good's syndrome with agranulocytosis was diagnosed at autopsy. Good's syndrome accompanied by agranulocytosis can follow a rapid clinical course and some cases remain asymptomatic until old age. Its prompt treatment is crucial.
authors.affiliation: Department of ER Medical Center, Osaka Police Hospital, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Okusu
authors.forename: Taiki
authors.initials: T
authors.lastname: Sato
authors.forename: Yoshitaka
authors.initials: Y
authors.lastname: Ogata
authors.forename: Shinpei
authors.initials: S
authors.lastname: Nagata
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Kozumi
authors.forename: Sung-Ho
authors.initials: SH
authors.lastname: Kim
authors.forename: Suguru
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Shigeru
authors.initials: S
authors.lastname: Yamayoshi
mesh_terms: D000361:Agammaglobulinemia / Q000276:immunology*; D000368:Aged; D000380:Agranulocytosis / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D001344:Autopsy; D017809:Fatal Outcome; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D008297:Male; D010612:Pharyngitis / Q000209:etiology; D013577:Syndrome; D013945:Thymoma / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*; D013953:Thymus Neoplasms / Q000150:complications / Q000188:drug therapy / Q000276:immunology / Q000473:pathology*