title: [ENTEROTOXIGENICITY OF STAPHYLOCOCCUS AUREUS STRAINS, ISOLATED FROM BREAST MILK OF WOMEN, FEEDING CHILDREN WITH INFECTIOUS PATHOLOGY].
abstract: OBJECTIVE
  Determination of enterotoxigenicity and ability to synthesize TSST-1 in S. aureus strains, isolated from breast milk of women, feeding children with infectious pathology.
  
  
  METHODS
  35 S. aureus strains, isolated from breast milk of women feeding children with varying infectious pathology in hospitals and as outpatients were studied for the presence of staphylococci enterotoxins (SE) of types A and B and toxic shock syndrome toxin (TSST-1). Determination of SEA, SEB and TSST-1 was carried out by enzyme immunoassay.
  
  
  RESULTS
  Toxins were detected in 94.2% of S. aureus strains. SEB was synthesized by 86.7%, SEA--34.3%, TSST-1--42.8% of S. aureus strains. Toxins were detected with equal frequencies in healthy women and women with inflammatory diseases of breasts. Differences in frequency of colonization of intestines of children receiving breast milk, infected with toxigenic and non-toxigenic staphylococci strains was not detected.
  
  
  CONCLUSIONS
  A high frequency of occurrence of enterotoxins and TSST-1 in S. aureus, isolated from breast milk of the mother during infectious pathology in the child was discovered. Enterotoxigenic strains can be detected in breast milk in healthy women. Study of the role of breast milk, infected with S. aureus, producing SEA, SEB And TSST-1 in development of child pathology is necessary.
authors.forename: F S
authors.initials: FS
authors.lastname: Fluer
authors.forename: I V
authors.initials: IV
authors.lastname: Nikolaeva
authors.forename: T Yu
authors.initials: TY
authors.lastname: Pavlova
authors.forename: V M
authors.initials: VM
authors.lastname: Bondarenko
authors.forename: S V
authors.initials: SV
authors.lastname: Fialkina
authors.forename: S I
authors.initials: SI
authors.lastname: Titarev
mesh_terms: D001427:Bacterial Toxins / Q000096:biosynthesis* / Q000302:isolation & purification; D001942:Breast Feeding / Q000009:adverse effects; D002353:Carrier State; D015169:Colony Count, Microbial; D004768:Enterotoxins / Q000096:biosynthesis* / Q000302:isolation & purification; D005260:Female; D006801:Humans; D007124:Immunoenzyme Techniques; D007223:Infant; D007422:Intestines / Q000382:microbiology; D008297:Male; D008895:Milk, Human / Q000382:microbiology*; D013203:Staphylococcal Infections / Q000175:diagnosis / Q000209:etiology* / Q000382:microbiology / Q000473:pathology; D013211:Staphylococcus aureus / Q000302:isolation & purification / Q000378:metabolism / Q000472:pathogenicity*; D018089:Superantigens / Q000096:biosynthesis* / Q000302:isolation & purification
chemical_list: D001427:Bacterial Toxins; D004768:Enterotoxins; D018089:Superantigens; C030107:enterotoxin F, Staphylococcal; C026066:enterotoxin A, Staphylococcal; C031818:enterotoxin B, staphylococcal