title: Hepatoblastoma in childhood, long term survival achieved: 2 case reports and literature review.
abstract: BACKGROUND
  Hepatoblastoma is the most common primary liver tumor for children under 5 years of age. It usually presents as an abdominal mass, symptomatic only when large enough to cause mass effect on nearby organs. Symptoms such as early satiety, anorexia, abdominal pain or weight loss are the most common. Diagnosis depends on imaging studies, AFP levels and percutaneous biopsy. Treatment modality is usually surgical with neoadjuvant chemotherapy.
  
  
  METHODS
  In this article, we present 2 cases of hepatoblastoma treated 15 years ago by neoadjuvant chemotherapy and surgery, and are presenting for long term follow-up with complete disease remission.
  
  
  CONCLUSIONS
  Complete resection and remission can be achieved as demonstrated below by our 2 cases of hepatoblastoma, especially when performing a true anatomical hepatectomy, along with a neoadjuvant chemotherapy regimen. Although one of the cases did not respond to chemotherapy very well a complete resection was achieved and therefore a disease free survival of 15 years.
  
  
  CONCLUSIONS
  Hepatoblastoma are rare tumors of the pediatric age group. Management depends highly on combined surgical and pediatric oncological knowledge. A complete disease remission can be achieved when both modalities are treatment are optimal. Therefore, hepatoblastoma cases should be referred to specialized centers for management.
authors.affiliation: General Surgery Resident, Saint Georges Hospital University Medical Center, Faculty of Medicine-University of Balamand, Beirut, Lebanon. Electronic address: antoine.el.asmar@gmail.com.
authors.forename: Antoine
authors.initials: A
authors.lastname: El Asmar
authors.affiliation: Associate Professor of Clinical Surgery, General and digestive Surgery-Oncologic Surgery, Saint Georges Hospital University Medical Center, Faculty of Medicine-University of Balamand, Beirut, Lebanon. Electronic address: ziadelrassi@gmail.com.
authors.forename: Ziad
authors.initials: Z
authors.lastname: El Rassi
keywords: Chemotherapy; Hepatoblastoma case reports; Long term survival; Surgical resection; Total remission