title: Perspective on Nanoparticle Technology for Biomedical Use.
abstract: This review gives a short overview on the widespread use of nanostructured and nanocomposite materials for disease diagnostics, drug delivery, imaging and biomedical sensing applications. Nanoparticle interaction with a biological matrix/entity is greatly influenced by its morphology, crystal phase, surface chemistry, functionalization, physicochemical and electronic properties of the particle. Various nanoparticle synthesis routes, characterization, and functionalization methodologies to be used for biomedical applications ranging from drug delivery to molecular probing of underlying mechanisms and concepts are described with several examples (150 references).
authors.forename: Ramesh
authors.initials: R
authors.lastname: Raliya
authors.forename: Tandeep
authors.initials: T
authors.lastname: Singh Chadha
authors.forename: Kelsey
authors.initials: K
authors.lastname: Haddad
authors.affiliation: School of Engineering and Applied Science, Washington University in St. Louis, St. Louis, MO-63130, USA. pbiswas@wustl.edu.
authors.forename: Pratim
authors.initials: P
authors.lastname: Biswas
mesh_terms: D000818:Animals; D035843:Biomedical Research; D016503:Drug Delivery Systems; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology; D010316:Particle Size; D013499:Surface Properties