title: Severe Cholestasis and Bile Acid Nephropathy From Anabolic Steroids Successfully Treated With Plasmapheresis.
abstract: Severe cholestasis with anabolic androgenic steroids is well-known to cause acute liver injury. Treatment is usually supportive after withdrawal of the offending agent. Acute kidney injury (AKI) frequently occurs in acute liver injury and may complicate management and prognosis. We highlight the use of plasmapheresis resulting in rapid improvement in cholestatic jaundice with resolution of AKI. Plasmapheresis should be considered in special cases in which there is progressive clinical decline despite supportive care.
authors.affiliation: Department of Medicine, Division of Gastroenterology, Washington University School of Medicine, St. Louis, MO.
authors.forename: Avegail
authors.initials: A
authors.lastname: Flores
authors.affiliation: Department of Medicine, Baylor University Medical Center, Dallas, TX.
authors.forename: Rosemary
authors.initials: R
authors.lastname: Nustas
authors.affiliation: Department of Medicine, Baylor University Medical Center, Dallas, TX; Dallas Renal Group, Dallas, TX.
authors.forename: Hoang-Lan
authors.initials: HL
authors.lastname: Nguyen
authors.affiliation: Department of Medicine, Baylor University Medical Center, Dallas, TX; Department of Medicine, Texas A&M Health Science Center, College of Medicine, Bryan, TX.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Rahimi