title: Focus Issue: The ins and outs of ORAI in immune cells.
abstract: This Focus Issue highlights research into cell-specific regulation of store-operated calcium entry through the ORAI/STIM channel complex. Understanding the properties of these channels and how ORAI activity is regulated will lead to a better molecular view of immune cell function and diseases involving the immune system.
authors.affiliation: Editor, Science Signaling, AAAS, Washington, DC 20005, USA. ngough@aaas.org.
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Gough
mesh_terms: D000818:Animals; D002118:Calcium / Q000276:immunology*; D000071739:Calcium Release Activated Calcium Channels / Q000276:immunology*; D006801:Humans; D046912:Multiprotein Complexes / Q000276:immunology*; D000071736:Stromal Interaction Molecules / Q000276:immunology*
chemical_list: D000071739:Calcium Release Activated Calcium Channels; D046912:Multiprotein Complexes; D000071736:Stromal Interaction Molecules; D002118:Calcium