title: Early goal-directed therapy: do we have a definitive answer?
authors.affiliation: Department of Intensive Care, CHIREC Hospitals, Université Libre de Bruxelles, Rue Wayez 35, Braine L'Alleud, 1420, Brussels, Belgium. ddebacke@ulb.ac.be.
authors.forename: Daniel
authors.identifier: http://orcid.org/0000-0001-9841-5762
authors.initials: D
authors.lastname: De Backer
authors.affiliation: Department of Intensive Care, Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium.
authors.forename: Jean-Louis
authors.initials: JL
authors.lastname: Vincent
mesh_terms: D006801:Humans; D007362:Intensive Care Units / Q000706:statistics & numerical data*; D015337:Multicenter Studies as Topic; D012720:Severity of Illness Index; D012772:Shock, Septic / Q000401:mortality / Q000628:therapy*; D013997:Time Factors