title: [Impacts on asthma at persistent stage and immune function in the patients treated with acupuncture for warming yang and benefiting qi].
abstract: OBJECTIVE
  To compare the difference in clinical efficacy on bronchial asthma at chronic persistent stage between acupuncture for warming yang and benefiting qi and seretide.
  
  
  METHODS
  One hundred and eighty patients of bronchial asthma at chronic persistent stage were randomized into an acupuncture group and a western medication group, 90 cases in each one. In the acupuncture group, acupuncture for warming yang and benefiting qi was applied at Dazhui (GV 14), Feishu (BL 13), Danzhong (CV 17), Dingchuan (EX-B 1), Jianshi (PC 5), Zhigou (TE 6), Taixi (KI 3) and Zusanli (ST 36), once every two days. In the western medication group, inhalation therapy with seretide was applied, 1 to 2 inhalations each time, twice a day. The treatment for 20 days was as one session in the two groups, at the intervals of 2 days after each session. Four sessions of treatment were required. The immune function indices were observed before and after treatment in the patients of two groups, named immunoglobulin IgG, IgM and IgE; peripheral T lymphocytes (CD3+), helper T lymphocytes (CD4+), inhibitory T lymphocytes (CD8+) and the ratio of CD4+ and CD8+; as well as the pulmonary ventilation function indices, named maximum pulmonary expiratory flow (PEF), forced expiratory volume in one second (FEV1) and forced vital capacity (FVC). The clinical efficacy was compared between the two groups.
  
  
  RESULTS
  The total effective rate was 93.3% (84/90) in the acupuncture group, better than 88.9% (80/90) in the western medication group (P < 0.05). After treatment, the immune function indices and pulmonary ventilation function indices were apparently improved as compared with those before treatment in the two groups (all P < 0.05). The improvements in the acupuncture group were much more significant (all P < 0.05).
  
  
  CONCLUSIONS
  Acupuncture for warming yang and benefiting qi effectively controls the symptoms of bronchial asthma at chronic persistent stage and improves immune and pulmonary functions. The efficacy is better than that of seretide.
authors.forename: Yilin
authors.initials: Y
authors.lastname: Xie
authors.forename: Wenrong
authors.initials: W
authors.lastname: Wan
authors.forename: Yinlong
authors.initials: Y
authors.lastname: Zhao
authors.forename: Junjie
authors.initials: J
authors.lastname: Xie
authors.forename: Qiuyan
authors.initials: Q
authors.lastname: Wu
mesh_terms: D015669:Acupuncture Points; D015670:Acupuncture Therapy / Q000295:instrumentation / Q000379:methods; D000293:Adolescent; D000328:Adult; D001249:Asthma / Q000276:immunology* / Q000503:physiopathology / Q000628:therapy*; D005260:Female; D005541:Forced Expiratory Volume; D006801:Humans; D007136:Immunoglobulins / Q000276:immunology; D008297:Male; D008875:Middle Aged; D019413:Qi; D013601:T-Lymphocytes / Q000276:immunology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D007136:Immunoglobulins