title: Postoperative analgesia after inguinal hernia repair - Comparison of ropivacaine with bupivacaine: A randomized controlled trial.
abstract: BACKGROUND
  Postoperative pain management by surgical site infiltration has an edge over other methods of analgesia as it is simple and has lesser side effects. This study was designed to compare the analgesic effects provided by bupivacaine, a classical long-acting local anesthetic and ropivacaine, a new amino amide local anesthetic agent.
  
  
  METHODS
  Ninety patients scheduled for elective inguinal herniorrhaphy were randomly allocated to one of the three groups: Group I - R 0.5, group II - R 0.25, and group III - B 0.25. General anesthesia was given. The surgical site was infiltrated before incision with 20 ml of drugs - ropivacaine 0.5% in group I, ropivacaine 0.25% in group II, bupivacaine 0.25% in group III. Intraoperatively hemodynamics were recorded every 15 min until the end of surgery and at the time of skin incision, at the time of cord pulling, and at the time of skin closure. Postoperatively, rest pain, pain on coughing, and pain on movements were assessed using visual analog scale (VAS) score immediately at the end of the surgery and hourly up to 4 h. The time of the first request for rescue analgesia was noted.
  
  
  RESULTS
  VAS scores at rest, during coughing and movements were higher in group R 0.25 and the time of rescue analgesia was shorter with group R 0.25 when compared with other groups.
  
  
  CONCLUSIONS
  Ropivacaine is less potent than bupivacaine at equal concentrations.
authors.affiliation: Department of Anaesthesiology and CC, JIPMER, Puducherry, India.
authors.forename: Suman Lata
authors.initials: SL
authors.lastname: Gupta
authors.affiliation: Department of Anaesthesiology and CC, JIPMER, Puducherry, India.
authors.forename: Prasanna Udupi
authors.initials: PU
authors.lastname: Bidkar
authors.affiliation: Department of Anaesthesiology and CC, JIPMER, Puducherry, India.
authors.forename: S
authors.initials: S
authors.lastname: Adinarayanan
authors.affiliation: Department of Anaesthesiology and CC, JIPMER, Puducherry, India.
authors.forename: M V S Satya
authors.initials: MV
authors.lastname: Prakash
authors.affiliation: Department of Anaesthesiology and CC, JIPMER, Puducherry, India.
authors.forename: L
authors.initials: L
authors.lastname: Aswini
keywords: Local infiltration; nerve block; postoperative analgesia; ropivacaine