title: Evidence-based review of diabetic macular edema management: Consensus statement on Indian treatment guidelines.
abstract: The purpose of the study was to review the current evidence and design a diabetic macular edema (DME) management guideline specific for India. The published DME guidelines from different organizations and publications were weighed against the practice trends in India. This included the recently approved drugs. DME management consisted of control of diabetes and other associated systemic conditions, such as hypertension and hyperlipidemia, and specific therapy to reduce macular edema. Quantification of macular edema is precisely made with the optical coherence tomography and treatment options include retinal laser, intravitreal anti-vascular endothelial growth factors (VEGF), and implantable dexamethasone. Specific use of these modalities depends on the presenting vision and extent of macular involvement. Invariable eyes with center-involving macular edema benefit from intravitreal anti-VEGF or dexamethasone implant therapy, and eyes with macular edema not involving the macula center benefit from retinal laser. The results are illustrated with adequate case studies and frequently asked questions. This guideline prepared on the current published evidence is meant as a guideline for the treating physicians.
authors.affiliation: L. V. Prasad Eye Institute, Hyderabad, Telangana, India.
authors.forename: Taraprasad
authors.initials: T
authors.lastname: Das
authors.forename: Ajay
authors.initials: A
authors.lastname: Aurora
authors.forename: Jay
authors.initials: J
authors.lastname: Chhablani
authors.forename: Anantharaman
authors.initials: A
authors.lastname: Giridhar
authors.forename: Atul
authors.initials: A
authors.lastname: Kumar
authors.forename: Rajiv
authors.initials: R
authors.lastname: Raman
authors.forename: Manish
authors.initials: M
authors.lastname: Nagpal
authors.forename: Raja
authors.initials: R
authors.lastname: Narayanan
authors.forename: Sundaram
authors.initials: S
authors.lastname: Natarajan
authors.forename: Kim
authors.initials: K
authors.lastname: Ramasamay
authors.forename: Mudit
authors.initials: M
authors.lastname: Tyagi
authors.forename: Lalit
authors.initials: L
authors.lastname: Verma
mesh_terms: D020533:Angiogenesis Inhibitors / Q000008:administration & dosage; D032921:Consensus; D003907:Dexamethasone / Q000008:administration & dosage; D003920:Diabetes Mellitus / Q000517:prevention & control; D003930:Diabetic Retinopathy / Q000175:diagnosis / Q000188:drug therapy*; D004343:Drug Implants; D019317:Evidence-Based Medicine; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007194:India; D058449:Intravitreal Injections; D017075:Laser Coagulation / Q000379:methods; D008269:Macular Edema / Q000175:diagnosis / Q000188:drug therapy*; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D041623:Tomography, Optical Coherence
chemical_list: D020533:Angiogenesis Inhibitors; D004343:Drug Implants; D005938:Glucocorticoids; D003907:Dexamethasone