title: Optical Coherence Tomography Findings in Anterior Chamber Ointment Globule after Phacoemulsification.
abstract: We present 2 cases of anterior chamber ointment with evidence of progressive endothelial cell loss. In both cases, an anterior segment optical coherence tomography (OCT) was similar to an OCT of a tobramycin-dexamethasone ointment placed on a pen tip. An anterior segment OCT also demonstrated the direct contact of the globule with the corneal endothelium. A gas chromatography/mass spectrometry analysis documented the similarity to tobramycin-dexamethasone ointment in 1 case. Anterior segment OCT can help in confirming the diagnosis. Corneal endothelial injury is a continuous process, and its clinical manifestation is related to the size of the globule, the initial endothelium count, and the duration of ointment contact, which is related to supine positioning. It is advisable to avoid ointments in the immediate postoperative period, especially in corneal wounds larger than 3 mm.
authors.affiliation: Department of Ophthalmology, American University of Beirut, Beirut, Lebanon; Department of Ophthalmology, Rafic Hariri University Hospital, Beirut, Lebanon.
authors.forename: Ahmad M
authors.initials: AM
authors.lastname: Mansour
authors.affiliation: Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.
authors.forename: Randa S
authors.initials: RS
authors.lastname: Haddad
authors.affiliation: Department of Ophthalmology, American University of Beirut, Beirut, Lebanon.
authors.forename: Haytham I
authors.initials: HI
authors.lastname: Salti
authors.affiliation: Department of Pathology and Laboratory Medicine, American University of Beirut, Beirut, Lebanon.
authors.forename: Zuhair
authors.initials: Z
authors.lastname: Habbal
keywords: Anterior chamber ointment globule; Optical coherence tomography; Phacoemulsification