title: Dental and Oral Lesions in HIV-Positive Individuals in East Bohemia--Czech Republic, Single Centre Experience.
abstract: BACKGROUND
  Human immunodeficiency virus (HIV) continues to be a serious health issue and one of the world most devastating epidemics. An estimated 1.5 million people died from AIDS-related illnesses in 2013, and an estimated 37 million people with AIDS have died worldwide since the epidemic has begun. HIV infection is known for its oral manifestations which causes discomfort and pain for infected individuals. The objective of this study was to document oral conditions of HIV positive patients and the pattern and frequency of oral and dental lesions.
  
  
  METHODS
  All patients with confirmed HIV infection who were treated at the Department of Dentistry, University Hospital in Hradec Králové, were examined.
  
  
  RESULTS
  During the study period, 29 HIV positive patients were examined and treated--19 men, 10 women, with mean age of 32.9 years (range 22-58 years). 72.41% patients received ART. In total, all patients underwent 186 visits. The most frequent treatments were associated with teeth and periodontal lesions (71.80%), oral mucosal lesions were diagnosed and treated only in 3.96% cases.
  
  
  CONCLUSIONS
  Since the introduction of ART, the frequency of oral mucosal lesions is minimal in patients with HIV infection.
authors.affiliation: Department of Dentistry, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic. martin.sembera@fnhk.cz.
authors.forename: Martin
authors.initials: M
authors.lastname: Šembera
authors.affiliation: Department of Dentistry, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic.
authors.forename: Vladimíra
authors.initials: V
authors.lastname: Radochová
authors.affiliation: Department of Dentistry, Charles University in Prague, Faculty of Medicine and University Hospital in Hradec Králové, Czech Republic.
authors.forename: Radovan
authors.initials: R
authors.lastname: Slezák
mesh_terms: D000328:Adult; D044966:Anti-Retroviral Agents / Q000627:therapeutic use; D002180:Candidiasis, Oral / Q000453:epidemiology; D015331:Cohort Studies; D018153:Czech Republic / Q000453:epidemiology; D003731:Dental Caries / Q000453:epidemiology; D003790:Dental Pulp Necrosis / Q000453:epidemiology; D005260:Female; D005891:Gingivitis / Q000453:epidemiology; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D017676:Lichen Planus, Oral / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009059:Mouth Diseases / Q000453:epidemiology*; D009062:Mouth Neoplasms / Q000453:epidemiology; D019226:Oral Ulcer / Q000453:epidemiology; D010518:Periodontitis / Q000453:epidemiology; D011671:Pulpitis / Q000453:epidemiology; D012514:Sarcoma, Kaposi / Q000453:epidemiology; D012793:Sialadenitis / Q000453:epidemiology; D013283:Stomatitis, Herpetic / Q000453:epidemiology; D014076:Tooth Diseases / Q000453:epidemiology*; D055815:Young Adult
chemical_list: D044966:Anti-Retroviral Agents
keywords: Dental lesions; HIV; Oral mucosal lesions