title: Reversible Posterior Leukoencephalopathy Syndrome Associated with Treatment for Acute Exacerbation of Ulcerative Colitis.
abstract: Reversible posterior leukoencephalopathy syndrome (RPLS) is a clinical syndrome of varying etiologies with similar neuroimaging findings. This is a case report of a 25-year-old woman who developed typical, neurological symptoms and magnetic resonance imaging abnormalities after treatment for the acute exacerbation of ulcerative colitis (UC), which included blood transfusion, the systemic administration of prednisolone, and the administration of metronidazole. It has been reported that these treatments may contribute to the development of RPLS. RPLS should therefore be considered in the differential diagnosis of UC patients who exhibit impaired consciousness, seizures or visual deficits during treatment. We report a rare case of RPLS in a patient with UC.
authors.affiliation: Department of Surgery, Asahikawa Medical University, Japan.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Kikuchi
authors.forename: Fumika
authors.initials: F
authors.lastname: Orii
authors.forename: Atsuo
authors.initials: A
authors.lastname: Maemoto
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Ashida
mesh_terms: D000890:Anti-Infective Agents / Q000009:adverse effects*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D001803:Blood Transfusion; D003093:Colitis, Ulcerative / Q000150:complications / Q000188:drug therapy*; D000075202:Contraindications; D003937:Diagnosis, Differential; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008795:Metronidazole / Q000009:adverse effects*; D054038:Posterior Leukoencephalopathy Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D011239:Prednisolone / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D008795:Metronidazole; D011239:Prednisolone