title: mRNA Expression of Ovine Angiopoietin-like Protein 4 Gene in Adipose Tissues.
abstract: Angiopoietin-like protein 4 (ANGPTL4) is involved in a variety of functions, including lipoprotein metabolism and angiogenesis. To reveal the role of ANGPTL4 in fat metabolism of sheep, ovine ANGPTL4 mRNA expression was analyzed in seven adipose tissues from two breeds with distinct tail types. Forty-eight animals with the gender ratio of 1:1 for both Guangling Large Tailed (GLT) and Small Tailed Han (STH) sheep were slaughtered at 2, 4, 6, 8, 10, and 12 months of age, respectively. Adipose tissues were collected from greater and lesser omental, subcutaneous, retroperitoneal, perirenal, mesenteric, and tail fats. Ontogenetic mRNA expression of ANGPTL4 in these adipose tissues from GTL and STH was studied by quantitative real time polymerase chain reaction. The results showed that ANGPTL4 mRNA expressed in all adipose tissues studied with the highest in subcutaneous and the lowest in mesenteric fat depots. Months of age, tissue and breed are the main factors that significantly influence the mRNA expression. These results provide new insights into ovine ANGPTL4 gene expression and clues for its function mechanism.
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Jiong-Jie
authors.initials: JJ
authors.lastname: Jing
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Xia-Li
authors.initials: XL
authors.lastname: Jia
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Li-Ying
authors.initials: LY
authors.lastname: Qiao
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Jian-Hua
authors.initials: JH
authors.lastname: Liu
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Liang
authors.affiliation: College of Animal Science and Technology, Shanxi Agricultural University, Taigu 030801, China.
authors.forename: Wen-Zhong
authors.initials: WZ
authors.lastname: Liu
keywords: ANGPTL4; Adipose Tissue; Sheep; mRNA Expression