title: Management of the pregnant mare and long-term consequences on the offspring.
abstract: The study of early developmental conditioning of health and disease in adulthood is particularly relevant in the horse, which is bred mainly to perform in demanding sport challenges. On the basis of this concept, the management of the broodmare could be considered an effective means to produce animals with the desired features. Knowledge on the Developmental Origins of Health and Disease in the equine species remains relatively scarce, with some experimental studies and one single epidemiologic study. Data highlight the determinant role of the maternal environment for postnatal body conformation, immune response, energy homeostasis, osteoarticular status and thyroidal, adrenocortical, and cardiovascular functions of the foal. Most research, however, focuses on the first months/years after birth. Long-term effects on the adult horse phenotype have not been investigated so far.
authors.affiliation: UMR 1198 Developmental Biology and Reproduction, French Institute for Agricultural Research (INRA), Jouy-en-Josas, France. Electronic address: peugnetpauline@gmail.com.
authors.forename: Pauline
authors.initials: P
authors.lastname: Peugnet
authors.affiliation: UMR 1198 Developmental Biology and Reproduction, French Institute for Agricultural Research (INRA), Jouy-en-Josas, France.
authors.forename: Morgane
authors.initials: M
authors.lastname: Robles
authors.affiliation: Experimental farm, French Horse and Riding Institute (IFCE), Chamberet, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Wimel
authors.affiliation: UMR 1198 Developmental Biology and Reproduction, French Institute for Agricultural Research (INRA), Jouy-en-Josas, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Tarrade
authors.affiliation: UMR 1198 Developmental Biology and Reproduction, French Institute for Agricultural Research (INRA), Jouy-en-Josas, France.
authors.forename: Pascale
authors.initials: P
authors.lastname: Chavatte-Palmer
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D000831:Animals, Newborn; D005260:Female; D006736:Horses / Q000254:growth & development / Q000502:physiology*; D011247:Pregnancy; D011270:Pregnancy, Animal
keywords: Developmental origins of health and disease; Embryo transfer; Equids; Nutrition; Placenta