title: Complete genome sequence of Lactobacillus helveticus CAUH18, a potential probiotic strain originated from koumiss.
abstract: Here we report the complete genome sequence of Lactobacillus helveticus CAUH18, a new strain isolated from traditional fermented dairy product koumiss. Its genome has a circular 2.16Mb chromosome with no plasmid. The genome sequence indicated that this strain harbors a gene cluster involved in a novel exopolysaccharides (EPS) biosynthesis and a gene encoding cell-surface aggregation-promoting factors (APFs) to facilitate its colonization in gastrointestinal tract (GIT). This genome sequence provides a basis for further studies about its molecular genetics and probiotic functions.
authors.affiliation: The Innovation Centre of Food Nutrition and Human Health (Beijing), College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Municipality, Beijing 100083, PR China.
authors.forename: Haoran
authors.initials: H
authors.lastname: An
authors.affiliation: The Innovation Centre of Food Nutrition and Human Health (Beijing), College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China.
authors.forename: Zhengyuan
authors.initials: Z
authors.lastname: Zhai
authors.affiliation: Key Laboratory of Functional Dairy, Co-constructed by Ministry of Education and Beijing Municipality, Beijing 100083, PR China.
authors.forename: Guohong
authors.initials: G
authors.lastname: Wang
authors.affiliation: The Innovation Centre of Food Nutrition and Human Health (Beijing), College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China.
authors.forename: Jiaxi
authors.initials: J
authors.lastname: Li
authors.affiliation: The Innovation Centre of Food Nutrition and Human Health (Beijing), College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, PR China. Electronic address: haoyl@cau.edu.cn.
authors.forename: Yanling
authors.initials: Y
authors.lastname: Hao
mesh_terms: D001482:Base Composition; D002876:Chromosomes, Bacterial / Q000235:genetics*; D003611:Dairy Products / Q000382:microbiology; D059646:Genome Size; D052198:Lactobacillus helveticus / Q000235:genetics / Q000302:isolation & purification*; D005810:Multigene Family; D019936:Probiotics; D017422:Sequence Analysis, DNA / Q000379:methods*
keywords: Exopolysaccharide; Genome; Lactobacillus helveticus CAUH18; Pacbio