title: Update in treatment options in pulmonary hypertension.
abstract: Significant developments have occurred in the field of pulmonary hypertension (PH) in the past 2 years, especially in terms of treatment options available. These include: approval of new drugs; evidence for use of initial combination therapies in pulmonary arterial hypertension; approved drugs for use in chronic thromboembolic disease not amenable to, or persistent after surgical thromboendarterectomy; and ongoing clinical trials in PH related to left heart disease and hypoxia. The field continues to evolve and address the challenges in treatment of this multifaceted disease with the aim to provide novel solutions and meet the needs of a growing population with PH. This has led to an extensive body of literature, ranging from case series to prospective, multicenter clinical trials, which will enhance the future of patient outcomes in PH. This contemporary review highlights the key articles in treatment updates for PH for the years 2013 to 2015.
authors.affiliation: Division of Cardiology, Allegheny General Hospital, Pittsburgh, Pennsylvania, USA. Electronic address: mkanwar@wpahs.org.
authors.forename: Manreet K
authors.initials: MK
authors.lastname: Kanwar
authors.affiliation: Division of Cardiology, Lillehei Heart Institute, University of Minnesota, Minneapolis, Minnesota, USA.
authors.forename: Thenappan
authors.initials: T
authors.lastname: Thenappan
authors.affiliation: Cliniques Universitaires de Bruxelles-Hôpital Erasme, Brussels, Belgium.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Vachiéry
mesh_terms: D002908:Chronic Disease; D004691:Endarterectomy; D006801:Humans; D006976:Hypertension, Pulmonary; D011446:Prospective Studies; D013923:Thromboembolism
keywords: clinical trials; pulmonary hypertension; pulmonary vascular disease; treatment; updates