title: Direct Oxidation of Aliphatic C-H Bonds in Amino-Containing Molecules under Transition-Metal-Free Conditions.
abstract: By employing a simple, inexpensive, and transition-metal-free oxidation system, secondary C-H bonds in a series of phthaloyl protected primary amines and amino acid derivatives were oxidized to carbonyls with good regioselectivities. This method could also be applied to oxidize tertiary C-H bonds and modify synthetic dipeptides.
authors.forename: Xin
authors.initials: X
authors.lastname: Li
authors.forename: Xing
authors.initials: X
authors.lastname: Che
authors.forename: Gui-Hua
authors.initials: GH
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
authors.forename: Jia-Lei
authors.initials: JL
authors.lastname: Yan
authors.forename: Yun-Fei
authors.initials: YF
authors.lastname: Zhang
authors.forename: Li-Sheng
authors.initials: LS
authors.lastname: Zhang
authors.affiliation: Academia Sinica , Institute of Chemistry, 128 Sect 2 Acad Road, Taipei 115, Taiwan.
authors.forename: Chao-Ping
authors.initials: CP
authors.lastname: Hsu
authors.forename: Yi Qin
authors.initials: YQ
authors.lastname: Gao
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Chinese Academy of Sciences , 345 Lingling Road, Shanghai 200032, China.
authors.forename: Zhang-Jie
authors.initials: ZJ
authors.lastname: Shi
mesh_terms: D000588:Amines / Q000737:chemistry*; D002244:Carbon / Q000737:chemistry; D002384:Catalysis; D004151:Dipeptides / Q000138:chemical synthesis / Q000737:chemistry*; D006859:Hydrogen / Q000737:chemistry; D015394:Molecular Structure; D010084:Oxidation-Reduction
chemical_list: D000588:Amines; D004151:Dipeptides; D002244:Carbon; D006859:Hydrogen