title: Esophageal Eosinophilia Treated With Long-Duration Proton Pump Inhibitor Therapy.
abstract: We present a case of proton pump inhibitor-responsive eosinophilic esophagitis (PPI-REE) in a patient with severe dysphagia and markedly elevated baseline esophageal eosinophilia that was previously deemed unresponsive to PPI. Upon reintroduction to PPI therapy with monthly endoscopy and dilation over the course of 4 months, the patient improved clinically and resolved her mucosal eosinophilia. Our case suggests that a longer duration of PPI therapy may be required for histologic improvement, especially in patients with very high mucosal eosinophil count.
authors.affiliation: Largo Medical Center, NOVA Southeastern University College of Osteopathic Medicine, Largo, FL.
authors.forename: Ernest L
authors.initials: EL
authors.lastname: DiGiovanni
authors.affiliation: Department of Pathology & Cell Biology, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: Anne L
authors.initials: AL
authors.lastname: Champeaux
authors.affiliation: Department of Pathology & Cell Biology, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: May R
authors.initials: MR
authors.lastname: Arroyo
authors.affiliation: Department of Medicine, Division of Gastroenterology, Joy McCann Culverhouse Center for Swallowing Disorders, University of South Florida Morsani College of Medicine, Tampa, FL.
authors.forename: Joel E
authors.initials: JE
authors.lastname: Richter