title: Stent-assisted coiling of intracranial aneurysms located on small vessels: midterm results with the LVIS Junior stent in 40 patients with 43 aneurysms.
abstract: BACKGROUND
  The Low-profile Visualized Intraluminal Support (LVIS) Junior stent is dedicated for endovascular treatment of wide-neck intracranial aneurysms located on small-diameter vessels (2-3.5 mm). This study reports midterm clinical and anatomical results of this device.
  
  
  METHODS
  This study was approved by authors' ethical committees. A retrospective review of our prospectively maintained database identified all patients treated by this stent in three institutions. Technical issues and immediate and mid-term anatomical and clinical outcomes were evaluated.
  
  
  RESULTS
  Forty patients (30 women/10 men, mean age of 55 years) with 43 aneurysms were identified. Mean aneurysm diameter was 5.6 mm (range, 2-13 mm). In all patients, treatment was successful and the stent could be precisely placed. There were three procedure-related complications, one stent thrombosis and two aneurysm ruptures, leading to immediate morbidity in one patient. Delayed ischemic events occurred in three patients including two transient attacks and one permanent deficit. The overall permanent morbidity rate was thus 5 %. No mortality occurred. Immediate aneurysm occlusion consisted of 36 complete occlusions (83.7 %), five neck remnants (11.6 %), and two incomplete occlusions (4.7 %). Twenty-seven patients (29 aneurysms) and 11 patients (11 aneurysms) had a 12- and 6-month angiographic follow-up, respectively. Final anatomical results included 36 complete occlusions (90 %) and four neck remnants (10 %). Two minor recanalizations were seen but did not require retreatment. Non-significant intrastent stenosis occurred in 7/40 followed-up cases (17.5 %).
  
  
  CONCLUSIONS
  The LVIS Junior stent appears safe and effective for endovascular treatment of wide-neck intracranial aneurysms located on small vessels. Midterm results show high rates of adequate and stable occlusion.
authors.affiliation: Department of Neuroradiology, Erasme University Hospital, 808 Route de Lennik, 1070, Bruxelles, Belgium.
authors.forename: Faisal
authors.initials: F
authors.lastname: Alghamdi
authors.affiliation: Department of Neuroradiology, Erasme University Hospital, 808 Route de Lennik, 1070, Bruxelles, Belgium.|Department of Radiology, Cliniques du Sud Luxembourg, Clinique Saint-Joseph, Arlon, Belgium.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Mine
authors.affiliation: Department of Neuroradiology, Erasme University Hospital, 808 Route de Lennik, 1070, Bruxelles, Belgium.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Morais
authors.affiliation: Department of Radiology, Erasme University Hospital, Bruxelles, Belgium.
authors.forename: Pietro
authors.initials: P
authors.lastname: Scillia
authors.affiliation: Department of Neuroradiology, Erasme University Hospital, 808 Route de Lennik, 1070, Bruxelles, Belgium. blubicz@ulb.ac.be.|Department of Radiology, Centre Hospitalier Régional Citadelle, Radiology, Liège, Belgium. blubicz@ulb.ac.be.
authors.forename: Boris
authors.initials: B
authors.lastname: Lubicz
mesh_terms: D001807:Blood Vessel Prosthesis; D002533:Cerebral Angiography / Q000379:methods; D019544:Equipment Failure Analysis; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000628:therapy*; D008137:Longitudinal Studies; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D008875:Middle Aged; D008904:Miniaturization; D011474:Prosthesis Design; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome
keywords: Coiling; Intracranial aneurysms; Stent