title: Evans Syndrome Secondary to Common Variable Immune Deficiency.
abstract: Evans syndrome is an underdiagnosed condition consisting of simultaneous or sequential combination of autoimmune hemolytic anemia and immune-mediated thrombocytopenia. We report a case of severe Evans syndrome presenting as altered mental status, a rare presenting sign of the disease. This case highlights the difficulty in diagnosing Evans syndrome and provides a review of the literature and management strategies for treating the disorder.
authors.affiliation: *Department of Pediatrics, Children's Hospital, University of Illinois Hospital & Health Sciences System †Department of Pediatrics, Rush University Medical Center, Chicago, IL ‡Departments of Pediatrics, University of North Carolina School of Medicine, Chapel Hill, NC.
authors.forename: James W
authors.initials: JW
authors.lastname: Antoon
authors.forename: Diana
authors.initials: D
authors.lastname: Metropulos
authors.forename: Benny L
authors.initials: BL
authors.lastname: Joyner
mesh_terms: D000293:Adolescent; D000744:Anemia, Hemolytic, Autoimmune / Q000175:diagnosis* / Q000209:etiology*; D017074:Common Variable Immunodeficiency / Q000150:complications*; D006801:Humans; D008297:Male; D013921:Thrombocytopenia / Q000175:diagnosis* / Q000209:etiology*