title: A sensitive fluorescent sensor for the detection of endogenous hydroxyl radicals in living cells and bacteria and direct imaging with respect to its ecotoxicity in living zebra fish.
abstract: We have synthesized a novel fluorescent probe, , which shown a high potential for imaging of endogenous ˙OH in living cells and various types of bacteria. In addition, it is an excellent sensor for in vivo imaging of ˙OH generated following treatment with TiO2NPs in zebra fish.
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Central Xianlie Road, Guangzhou 510070, P. R. China. xumy@gdim.cn.
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Central Xianlie Road, Guangzhou 510070, P. R. China. xumy@gdim.cn.
authors.forename: Juan
authors.initials: J
authors.lastname: Du
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Central Xianlie Road, Guangzhou 510070, P. R. China. xumy@gdim.cn.
authors.forename: Da
authors.initials: D
authors.lastname: Song
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Central Xianlie Road, Guangzhou 510070, P. R. China. xumy@gdim.cn.
authors.forename: Meiying
authors.initials: M
authors.lastname: Xu
authors.affiliation: State Key Laboratory of Applied Microbiology Southern China, Guangdong Provincial Key Laboratory of Microbial Culture Collection and Application, Guangdong Institute of Microbiology, 100 Central Xianlie Road, Guangzhou 510070, P. R. China. xumy@gdim.cn.
authors.forename: Guoping
authors.initials: G
authors.lastname: Sun
mesh_terms: D000818:Animals; D001419:Bacteria / Q000737:chemistry* / Q000187:drug effects*; D002470:Cell Survival / Q000187:drug effects; D004625:Embryo, Nonmammalian / Q000737:chemistry / Q000187:drug effects*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006367:HeLa Cells; D006801:Humans; D017665:Hydroxyl Radical / Q000032:analysis* / Q000633:toxicity*; D007211:Indoles / Q000737:chemistry*; D057230:Limit of Detection; D015394:Molecular Structure; D053758:Nanoparticles / Q000737:chemistry; D010640:Phenothiazines / Q000737:chemistry*; D014025:Titanium / Q000737:chemistry; D015027:Zebrafish
chemical_list: D005456:Fluorescent Dyes; D007211:Indoles; C000613473:MPT-Cy2; C000613474:OMPT-Cy2; D010640:Phenothiazines; C009495:titanium dioxide; D017665:Hydroxyl Radical; D014025:Titanium