title: COAGULASE-NEGATIVE STAPHYLOCOCCUS-INDUCED FROSTED BRANCH ANGIITIS AFTER INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR INJECTION.
abstract: OBJECTIVE
  To describe a case of frosted branch angiitis after intravitreal ranibizumab injection.
  
  
  METHODS
  Retrospective chart review.
  
  
  RESULTS
  A patient with a history of neovascular age-related macular degeneration underwent intravitreal ranibizumab injection and subsequently developed coagulase-negative Staphylococcus endophthalmitis with findings of frosted branch angiitis.
  
  
  CONCLUSIONS
  Endophthalmitis presenting as frosted branch angiitis is a rare complication after intravitreal anti-vascular endothelial growth factor injection. Early recognition is critical to optimize outcomes. To our knowledge, this is the second reported case of frosted branch angiitis as a presentation of endophthalmitis with coagulase-negative Staphylococcus.
authors.affiliation: *Thomas Jefferson School of Medicine, Philadelphia, Pennsylvania; and †Mid Atlantic Retina, The Retina Service of Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania.
authors.forename: Rebekah H
authors.initials: RH
authors.lastname: Gensure
authors.forename: Jason
authors.initials: J
authors.lastname: Hsu
authors.forename: Jay
authors.initials: J
authors.lastname: Federman
authors.forename: Carl
authors.initials: C
authors.lastname: Park
authors.forename: Marc J
authors.initials: MJ
authors.lastname: Spirn
mesh_terms: D000369:Aged, 80 and over; D020533:Angiogenesis Inhibitors / Q000008:administration & dosage*; D009877:Endophthalmitis / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000382:microbiology*; D005260:Female; D006801:Humans; D058449:Intravitreal Injections / Q000009:adverse effects*; D000069579:Ranibizumab / Q000008:administration & dosage*; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000209:etiology*; D013210:Staphylococcus / Q000302:isolation & purification*; D014657:Vasculitis / Q000382:microbiology*
chemical_list: D020533:Angiogenesis Inhibitors; D000069579:Ranibizumab