title: Randomised controlled trial of referral to a telephone-based weight management and healthy lifestyle programme for patients with knee osteoarthritis who are overweight or obese: a study protocol.
abstract: BACKGROUND
  Knee osteoarthritis (OA) is one of the most common chronic diseases worldwide and is associated with significant pain and disability. Clinical practice guidelines consistently recommend weight management as a core aspect of care for overweight and obese patients with knee OA; however, provision of such care is suboptimal. Telephone-based interventions offer a novel approach to delivery of weight management care in these patients. The aim of the proposed study is to assess the effectiveness of referral to a telephone-based weight management and healthy lifestyle programme, previously shown to be effective in changing weight, in improving knee pain intensity in overweight or obese patients with knee OA, compared to usual care.
  
  
  METHODS
  A parallel, randomised controlled trial will be undertaken. Patients with OA of the knee who are waiting for an outpatient orthopaedic consultation at a tertiary referral public hospital within New South Wales, Australia, will be allocated to either an intervention or a control group (1:1 ratio). After baseline data collection, patients in the intervention group will receive a 6-month telephone-based intervention, and patients in the control group will continue with usual care. Surveys will be conducted at baseline, 6 and 26 weeks post-randomisation. The study requires 60 participants per group to detect a two-point difference in pain intensity (primary outcome) 26 weeks after baseline.
  
  
  BACKGROUND
  The study is approved by the Hunter New England Health Human Research Ethics Committee (13/12/11/5.18) and the University of Newcastle Human Research Ethics Committee (H-2015-0043). The results will be disseminated in peer-reviewed journals and at scientific conferences.
  
  
  BACKGROUND
  ACTRN12615000490572, Pre-results.
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia.
authors.forename: Kate M
authors.initials: KM
authors.lastname: O'Brien
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia.
authors.forename: John
authors.initials: J
authors.lastname: Wiggers
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia.
authors.forename: Amanda
authors.initials: A
authors.lastname: Williams
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Campbell
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia.
authors.forename: Luke
authors.identifier: http://orcid.org/0000-0002-6178-3868
authors.initials: L
authors.lastname: Wolfenden
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia.
authors.forename: Serene
authors.initials: S
authors.lastname: Yoong
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia.
authors.forename: Emma K
authors.initials: EK
authors.lastname: Robson
authors.affiliation: Neuroscience Research Australia, University of New South Wales, Randwick, New South Wales, Australia Prince of Wales Clinical School, University of NSW, Randwick, New South Wales, Australia.
authors.forename: James
authors.initials: J
authors.lastname: McAuley
authors.affiliation: Ambulatory Care Centre, John Hunter Hospital, Newcastle, New South Wales, Australia.
authors.forename: Robin
authors.initials: R
authors.lastname: Haskins
authors.affiliation: The George Institute for Global Health, University of Sydney, Sydney New South Wales, Australia.
authors.forename: Steven J
authors.initials: SJ
authors.lastname: Kamper
authors.affiliation: Hunter New England Population Health, Wallsend, New South Wales, Australia Hunter Medical Research Institute, Newcastle, New South Wales, Australia University of Newcastle, Newcastle, New South Wales, Australia The George Institute for Global Health, University of Sydney, Sydney New South Wales, Australia.
authors.forename: Christopher
authors.initials: C
authors.lastname: Williams
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D009517:New South Wales / Q000453:epidemiology; D009765:Obesity / Q000150:complications / Q000453:epidemiology / Q000517:prevention & control*; D020370:Osteoarthritis, Knee / Q000453:epidemiology / Q000503:physiopathology / Q000628:therapy*; D015397:Program Evaluation; D012017:Referral and Consultation; D040242:Risk Reduction Behavior; D013689:Telephone; D016896:Treatment Outcome; D061217:Weight Reduction Programs
keywords: PAIN MANAGEMENT