title: The mPower study, Parkinson disease mobile data collected using ResearchKit.
abstract: Current measures of health and disease are often insensitive, episodic, and subjective. Further, these measures generally are not designed to provide meaningful feedback to individuals. The impact of high-resolution activity data collected from mobile phones is only beginning to be explored. Here we present data from mPower, a clinical observational study about Parkinson disease conducted purely through an iPhone app interface. The study interrogated aspects of this movement disorder through surveys and frequent sensor-based recordings from participants with and without Parkinson disease. Benefitting from large enrollment and repeated measurements on many individuals, these data may help establish baseline variability of real-world activity measurement collected via mobile phones, and ultimately may lead to quantification of the ebbs-and-flows of Parkinson symptoms. App source code for these data collection modules are available through an open source license for use in studies of other conditions. We hope that releasing data contributed by engaged research participants will seed a new community of analysts working collaboratively on understanding mobile health data to advance human health.
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Brian M
authors.identifier: http://orcid.org/0000-0002-2412-6826
authors.initials: BM
authors.lastname: Bot
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Christine
authors.identifier: http://orcid.org/0000-0002-2986-385X
authors.initials: C
authors.lastname: Suver
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Elias Chaibub
authors.initials: EC
authors.lastname: Neto
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Kellen
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Arno
authors.initials: A
authors.lastname: Klein
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Bare
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Megan
authors.initials: M
authors.lastname: Doerr
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Abhishek
authors.initials: A
authors.lastname: Pratap
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: John
authors.initials: J
authors.lastname: Wilbanks
authors.affiliation: Center for Human Experimental Therapeutics, University of Rochester Medical Center, Rochester, New York 14642, USA.
authors.forename: E Ray
authors.initials: ER
authors.lastname: Dorsey
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Stephen H
authors.initials: SH
authors.lastname: Friend
authors.affiliation: Sage Bionetworks, Seattle, Washington 98109, USA.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Trister
mesh_terms: D040421:Cell Phone; D003625:Data Collection; D066264:Datasets as Topic; D006801:Humans; D010300:Parkinson Disease; D017216:Telemedicine