title: Effect of digluconate chlorhexidine on bond strength between dental adhesive systems and dentin: A systematic review.
abstract: OBJECTIVE
  This study aimed to systematically review the literature for the effect of digluconate chlorhexidine (CHX) on bond strength between dental adhesive systems and dentin of composite restorations.
  
  
  METHODS
  The electronic databases that were searched to identify manuscripts for inclusion were Medline via PubMed and Google search engine. The search strategies were computer search of the database and review of reference lists of the related articles. Search words/terms were as follows: (digluconate chlorhexidine*) AND (dentin* OR adhesive system* OR bond strength*).
  
  
  RESULTS
  Bond strength reduction after CHX treatments varied among the studies, ranging 0-84.9%. In most of the studies, pretreatment CHX exhibited lower bond strength reduction than the control experimental groups. Researchers who previously investigated the effect of CHX on the bond strength of dental adhesive systems on dentin have reported contrary results, which may be attributed to different experimental methods, different designs of the experiments, and different materials investigated.
  
  
  CONCLUSIONS
  Further investigations, in particular clinical studies, would be necessary to clarify the effect of CHX on the longevity of dentin bonds.
authors.affiliation: Department of Operative Dentistry, School of Dentistry, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Dionysopoulos
keywords: Adhesive systems; bond strength; composite resins; dentin; digluconate chlorhexidine (CHX)