title: Eosinophilic colitis.
abstract: A 57-year-old man, diagnosed with colon cancer stage III in July/2010, underwent surgery and received adjuvant chemotherapy with FOLFOX 4 (5-fluorouracil; calcium folinate and oxaliplatin), which ended in March/2011 after 12-cycles. It was then decided to maintain periodical surveillance. About 1 year later, the patient developed several episodes of diarrhoea, mainly during the night, and presented persistent peripheral eosinophilia in the blood count (range 585-1300 eosinophils/µL). Colonoscopy was performed, with the histological result showing eosinophilic infiltration of the colon, compatible with eosinophilic colitis. The patient was treated with a short course of budesonide, achieving resolution of symptoms, and has remained asymptomatic.
authors.affiliation: Department of Medical Oncology, Portuguese Institute of Oncology Francisco Gentil, Coimbra, Portugal.
authors.forename: Isabel José
authors.initials: IJ
authors.lastname: Dionísio de Sousa
authors.affiliation: Department of Medical Oncology, Portuguese Institute of Oncology Francisco Gentil, Coimbra, Portugal.
authors.forename: Nuno
authors.initials: N
authors.lastname: Bonito
authors.affiliation: Department of Medical Oncology, Portuguese Institute of Oncology Francisco Gentil, Coimbra, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Pais
authors.affiliation: Department of Medical Oncology, Portuguese Institute of Oncology Francisco Gentil, Coimbra, Portugal.
authors.forename: Helena
authors.initials: H
authors.lastname: Gervásio
mesh_terms: D019819:Budesonide / Q000627:therapeutic use; D003092:Colitis / Q000175:diagnosis* / Q000188:drug therapy*; D003113:Colonoscopy; D004802:Eosinophilia / Q000175:diagnosis* / Q000188:drug therapy*; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D005938:Glucocorticoids; D019819:Budesonide