title: Anti-diarrhoeal Activity.
abstract: Diarrhoea is characterized by an increase in the frequency of bowel movements, wet stool and abdominal pains. It is the world's third highest killer disease, contributing substantially to paediatric morbidity and mortality, especially in the malnourished. Antibiotics used as anti-diarrhoeal drugs sometimes provoke adverse effects and microorganisms tend to develop resistance towards them. Therefore, the search for safe and more effective agents from plant origin using standard protocols of charcoal meal-induced diarrhoea has been defined in this chapter.
mesh_terms: D000818:Animals; D000930:Antidiarrheals / Q000302:isolation & purification / Q000494:pharmacology*; D065132:Bioprospecting / Q000379:methods*; D002606:Charcoal; D003967:Diarrhea / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control*; D004195:Disease Models, Animal; D055808:Drug Discovery / Q000379:methods*; D005260:Female; D005769:Gastrointestinal Motility / Q000187:drug effects; D007421:Intestine, Small / Q000187:drug effects / Q000503:physiopathology; D008297:Male; D064209:Phytochemicals / Q000302:isolation & purification / Q000494:pharmacology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D010946:Plants, Medicinal; D017208:Rats, Wistar; D013997:Time Factors
chemical_list: D000930:Antidiarrheals; D064209:Phytochemicals; D010936:Plant Extracts; D002606:Charcoal