title: The post-analytical phase of histopathology practice: Storage, retention and use of human tissue specimens.
abstract: There are several aspects to a histopathology practice besides the acquisition of biopsy specimens and histopathological diagnosis. Pathology Departments are home to an abundant source of knowledge in the form of stored specimens and slides. We attempt to highlight the importance of regulation of storage, retention, and appropriate use of human tissue material in research and ownership rights to the same. We also discuss requirement and waiver of informed consent for scientific work involving the use of such tissues, which in the absence of defined laws come under the purview of Institution Review Boards. Pathology Departments, under the binding of the parent institution, are conceded the responsibility of maintenance and retention of pathology specimens. This communication highlights some of the important aspects in human tissue material handling and research, underscoring the necessity for established regulations regarding the same.
authors.affiliation: Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal University, Mangalore, Karnataka, India.
authors.forename: Supriya Nikita
authors.initials: SN
authors.lastname: Kapila
authors.affiliation: Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal University, Mangalore, Karnataka, India.
authors.forename: Karen
authors.initials: K
authors.lastname: Boaz
authors.affiliation: Department of Oral Pathology and Microbiology, Manipal College of Dental Sciences, Manipal University, Mangalore, Karnataka, India.
authors.forename: Srikant
authors.initials: S
authors.lastname: Natarajan
keywords: Archival tissue; biospecimens; informed consent; pathology; storage