title: The Potential Application of Biomaterials in Cardiac Stem Cell Therapy.
abstract: Biomaterials play a vital role in the field of regenerative medicine and tissue engineering. To date, a large number of biomaterials have been used in cardiovascular research and application. Recently, biomaterials have held a lot of promise in cardiac stem cell therapy. They are used in cardiac tissue engineering to form scaffolds for cellular transplantation, promote angiogenesis, enhance transplanted cell engraftment or influence cell migration. The science of biomaterial designing has evolved to an extent where they can be designed to mimic the microenvironment of a cardiac tissue in vivo and contribute in deciding the fate of transplanted stem cells and induce cardiac lineage oriented stem cell differentiation. In this review, we focus on biomaterials used in cardiovascular stem cell research, tissue engineering and regenerative medicine and conclude with an outlook on future impacts of biomaterial in medical sciences.
authors.forename: Raja Ghazanfar Ali
authors.initials: RG
authors.lastname: Sahito
authors.forename: Poornima
authors.initials: P
authors.lastname: Sureshkumar
authors.forename: Isaia
authors.initials: I
authors.lastname: Sotiriadou
authors.forename: Sureshkumar Perumal
authors.initials: SP
authors.lastname: Srinivasan
authors.forename: Davood
authors.initials: D
authors.lastname: Sabour
authors.forename: Jürgen
authors.initials: J
authors.lastname: Hescheler
authors.forename: Kurt
authors.initials: K
authors.lastname: Pfannkuche
authors.affiliation: Institute for Neurophysiology and Center for Molecular Medicine Cologne (CMMC), University of Cologne, Robert-Koch-Str. 39, 50931, Cologne, Germany. a.sachinidis@uni-koeln.de.
authors.forename: Agapios
authors.initials: A
authors.lastname: Sachinidis
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D006321:Heart / Q000502:physiology; D006801:Humans; D009206:Myocardium / Q000166:cytology*; D012038:Regeneration; D044968:Regenerative Medicine / Q000379:methods*; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells / Q000166:cytology*; D023822:Tissue Engineering / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials