title: Pd(II)-Catalyzed ortho-C-H Olefination/Dearomatization of N-Aryl Ureas: An Approach to Imine Derivatives.
abstract: An unprecedented approach for the synthesis of imine derivatives was achieved via a Pd(II)-catalyzed dearomatization reaction of N-aryl ureas with internal alkynes. The corresponding spirocyclic imine derivatives were obtained with 20 examples in good to excellent yields. Mechanistic investigation indicated that an interesting 1,3-palladium migration process led to the α-regioselective dearomatization when 2-naphthyl ureas were used as the substrates. Fused ring products could also be obtained to further prove this migration process.
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Pingping
authors.initials: P
authors.lastname: Jiang
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Yongbao
authors.initials: Y
authors.lastname: Xu
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Fuxing
authors.initials: F
authors.lastname: Sun
authors.affiliation: State Grid Jilin Province Electric Power Research Institute , 4433 Renmin Street, Changchun 130021, China.
authors.forename: Xufei
authors.initials: X
authors.lastname: Liu
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Li
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Renfu
authors.initials: R
authors.lastname: Yu
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.affiliation: International Joint Research Laboratory of Nano-Micro Architecture Chemistry (NMAC), Department of Organic Chemistry, College of Chemistry, Jilin University , 2699 Qianjin Street, Changchun 130012, China.|State Grid Jilin Province Electric Power Research Institute , 4433 Renmin Street, Changchun 130021, China.
authors.forename: Qifeng
authors.initials: Q
authors.lastname: Wang