title: Terbinafine-induced lichenoid drug eruption.
abstract: Drug-induced lichen planus has been induced by antibiotics, anticonvulsants, antidiabetics, antimalarials, antitubercular drugs, antihypertensives, psychiatric drugs, chemotherapeutic agents, diuretic, heavy metals, NSAIDs, etc. Terbinafine, an antifungal agent, is widely used for dermatophyte infections and onychomycosis. Cutaneous adverse effects of terbinafine are rarely reported. Here, we report a case of terbinafine-induced lichenoid drug eruption in a 22-year-old who presented with generalized lichenoid eruption 2 weeks after terbinafine initiation of. The body and lip cleared completely after 8 weeks of drug withdrawal; nail change cleared after 12 weeks.
authors.affiliation: a Department of Dermatovenereology , the Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou, Guangdong , P.R. China and.
authors.forename: Yue
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: a Department of Dermatovenereology , the Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou, Guangdong , P.R. China and.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: a Department of Dermatovenereology , the Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou, Guangdong , P.R. China and.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Chen
authors.affiliation: a Department of Dermatovenereology , the Third Affiliated Hospital of Sun Yat-Sen University , Guangzhou, Guangdong , P.R. China and.
authors.forename: Wei
authors.initials: W
authors.lastname: Lai
authors.affiliation: b Department of Dermatology , University of California, School of Medicine , San Fransico, CA, USA.
authors.forename: Howard I
authors.initials: HI
authors.lastname: Maibach
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D006801:Humans; D017512:Lichenoid Eruptions / Q000139:chemically induced* / Q000473:pathology; D008297:Male; D009281:Naphthalenes / Q000009:adverse effects*; D012867:Skin / Q000187:drug effects / Q000473:pathology; D000077291:Terbinafine; D014005:Tinea / Q000188:drug therapy; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine
keywords: Drug adverse; lichenoid drug eruption; terbinafine