title: [How some commensal bacteria would exacerbate colorectal carcinogenesis?].
abstract: The gut microbiota maintains a relationship with its host with strong mutual benefits. Changes in the composition of the intestinal microbiota have been detected in colorectal cancer patients to the extent that it is now considered as a real contributing factor in this pathology. In this review, we focus on three commensal bacterial species, namely Bacteroides fragilis, Fusobacterium nucleatum, and Escherichia coli, which seem to emerge as pathogens and to contribute to colorectal carcinogenesis through their inflammatory and oncogenic properties.
authors.affiliation: UMR1071 Inserm-université d'Auvergne, INRA USC2018, 28, place Henri Dunant, 63000 Clermont-Ferrand, France - Laboratoire interaction hôte-pathogène, INRS-institut Armand Frappier, 531, boulevard des Prairies, Laval, QC, Canada.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Raisch
authors.affiliation: UMR1071 Inserm-université d'Auvergne, INRA USC2018, 28, place Henri Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Dalmasso
authors.affiliation: UMR1071 Inserm-université d'Auvergne, INRA USC2018, 28, place Henri Dunant, 63000 Clermont-Ferrand, France - Centre hospitalier universitaire, 58, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: Richard
authors.initials: R
authors.lastname: Bonnet
authors.affiliation: UMR1071 Inserm-université d'Auvergne, INRA USC2018, 28, place Henri Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Barnich
authors.affiliation: UMR1071 Inserm-université d'Auvergne, INRA USC2018, 28, place Henri Dunant, 63000 Clermont-Ferrand, France.
authors.forename: Mathilde
authors.initials: M
authors.lastname: Bonnet
authors.affiliation: UMR1071 Inserm-université d'Auvergne, INRA USC2018, 28, place Henri Dunant, 63000 Clermont-Ferrand, France - UMR 1324 INRA, 6265 CNRS, Université de Bourgogne Franche-Comté, Centre des Sciences du goût et de l'alimentation, Dijon, France.
authors.forename: Marie-Agnès
authors.initials: MA
authors.lastname: Bringer
mesh_terms: D000818:Animals; D018407:Bacterial Physiological Phenomena; D001441:Bacteroides fragilis / Q000472:pathogenicity; D063646:Carcinogenesis / Q000473:pathology; D015179:Colorectal Neoplasms / Q000382:microbiology* / Q000473:pathology*; D018450:Disease Progression; D004926:Escherichia coli / Q000472:pathogenicity; D016967:Fusobacterium nucleatum / Q000472:pathogenicity; D041981:Gastrointestinal Tract / Q000382:microbiology / Q000473:pathology; D006801:Humans; D013559:Symbiosis / Q000502:physiology*