title: Automated Lung Segmentation from HRCT Scans with Diffuse Parenchymal Lung Diseases.
abstract: Performing accurate and fully automated lung segmentation of high-resolution computed tomography (HRCT) images affected by dense abnormalities is a challenging problem. This paper presents a novel algorithm for automated segmentation of lungs based on modified convex hull algorithm and mathematical morphology techniques. Sixty randomly selected lung HRCT scans with different abnormalities are used to test the proposed algorithm, and experimental results show that the proposed approach can accurately segment the lungs even in the presence of disease patterns, with some limitations in the apices and bases of lungs. The algorithm demonstrates a high segmentation accuracy (dice similarity coefficient = 98.62 and shape differentiation metrics dmean = 1.39 mm, and drms = 2.76 mm). Therefore, the developed automated lung segmentation algorithm is a good candidate for the first stage of a computer-aided diagnosis system for diffuse lung diseases.
authors.affiliation: Vasireddy Venkatadri Institute of Technology, Nambur, Guntur, AP, India. pulagamammireddy@gmail.com.
authors.forename: Ammi Reddy
authors.initials: AR
authors.lastname: Pulagam
authors.affiliation: Vasireddy Venkatadri Institute of Technology, Nambur, Guntur, AP, India.
authors.forename: Giri Babu
authors.initials: GB
authors.lastname: Kande
authors.affiliation: Lakireddy Bali Reddy College of Engineering, Mylavaram, Vijayawada, AP, India.
authors.forename: Venkata Krishna Rao
authors.initials: VK
authors.lastname: Ede
authors.affiliation: Acharya Nagrjuna University, Nagarjuna Nagar, Guntur, AP, India.
authors.forename: Ramesh Babu
authors.initials: RB
authors.lastname: Inampudi
mesh_terms: D000465:Algorithms; D001980:Bronchi / Q000000981:diagnostic imaging; D003936:Diagnosis, Computer-Assisted; D006801:Humans; D008168:Lung / Q000000981:diagnostic imaging*; D008171:Lung Diseases / Q000000981:diagnostic imaging*; D017563:Lung Diseases, Interstitial / Q000000981:diagnostic imaging; D013902:Radiography, Thoracic / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014132:Trachea / Q000000981:diagnostic imaging
keywords: Convex hull; Flood filling; Index terms—HRCT; Lung parenchyma