title: Efficient multi-click approach to well-defined two-faced octasilsesquioxanes: the first perfect Janus nanocube.
abstract: The preparation of the first structurally well-defined Janus nanocube showing two chemically distinct opposed faces is described. The synthetic approach is based on a highly efficient and symmetry-controlled CuAAC functionalization of an octa-azido cubic silsesquioxane with a conformationally constrained tetra-alkyne with an appropriate spatial orientation of the triple bonds.
authors.affiliation: Instituto de Química Orgánica General, IQOG-CSIC, Juan de la Cierva 3, 28006 Madrid, Spain. jl.chiara@csic.es.
authors.forename: Alberto
authors.initials: A
authors.lastname: Blázquez-Moraleja
authors.forename: M
authors.initials: M
authors.lastname: Eugenia Pérez-Ojeda
authors.forename: José Ramón
authors.initials: JR
authors.lastname: Suárez
authors.forename: M
authors.initials: M
authors.lastname: Luisa Jimeno
authors.forename: Jose Luis
authors.initials: JL
authors.lastname: Chiara