title: Maternal Sleep Disordered Breathing and Neonatal Outcome.
abstract: BACKGROUND
  It has been suggested that sleep disordered breathing (SDB) during pregnancy may adversely influence maternal as well as fetal well being.
  
  
  OBJECTIVE
  To examine the effect of maternal SDB on neonatal neurological examination and perinatal complications.
  
  
  METHODS
  Pregnant women of singleton uncomplicated pregnancies were prospectively recruited from a community and hospital low risk obstetric surveillance. All participants completed a sleep questionnaire in the second trimester and underwent ambulatory sleep evaluation (WatchPAT, Itamar Medical, Caesarea, Israel). They were categorized as SDB (apnea hypopnea index > 5) and non-SDB. Maternal and newborn records were reviewed and a neonatal neurologic examination was conducted during the first 48 hours.
  
  
  RESULTS
  The study group included 44 women and full-term infants; 11 of the women (25%) had SDB. Mean maternal age of the SDB and non-SDB groups was 32.3 ± 2.8 and 32.5 ± 4.7 years, respectively (P = 0.86). Mean body mass index before the pregnancy in the SDB and non-SDB groups was 25.8 ± 4.7 and 22.0 ± 2.5 kg/m2, respectively (P = 0.028). No differences were found between infants born to mothers with SDB and non-SDB in birth weight (3353.8 ± 284.8 vs. 3379.1 ± 492.4 g), gestational age (39.5 ± 0.9 vs. 39.2 ± 1.5 weeks), 5 minute Apgar scores (9.8 ± 0.6 vs. 9.9 ± 0.3), and neurologic examination scores (95.2 ± 3.9 vs. 94.6 ± 4.1). P value for all was not significant.
  
  
  CONCLUSIONS
  Our preliminary results suggest that maternal mild SDB during pregnancy has no adverse effect on neonatal neurologic examination or on perinatal complications.
authors.forename: Haim
authors.initials: H
authors.lastname: Bassan
authors.forename: Shimrit
authors.initials: S
authors.lastname: Uliel-Sibony
authors.forename: Shlomit
authors.initials: S
authors.lastname: Katsav
authors.forename: Mira
authors.initials: M
authors.lastname: Farber
authors.forename: Riva
authors.initials: R
authors.lastname: Tauman
mesh_terms: D000328:Adult; D001034:Apgar Score; D001724:Birth Weight; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007557:Israel; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012890:Sleep / Q000502:physiology; D012891:Sleep Apnea Syndromes / Q000150:complications* / Q000453:epidemiology; D011795:Surveys and Questionnaires