title: An unusual case of nephrotic syndrome.
abstract: Nephrotic syndrome can be rarely due to inherited disorders of enzymes. One such variety is lecithin cholesterol acyltransferase deficiency. It leads to accumulation of unesterified cholesterol in the eye and other organs. We report a case of nephrotic syndrome with cloudy cornea and hypocholesterolemia with foam cells and lipid deposits on renal biopsy. Awareness about this rare disease may help in the early institution of specific measures to prevent progression to end-stage renal disease.
authors.affiliation: Department of Nephrology, Osmania General Hospital and Medical College, Telangana, Hyderabad, India.
authors.forename: M
authors.initials: M
authors.lastname: Sahay
authors.affiliation: Department of Nephrology, Osmania General Hospital and Medical College, Telangana, Hyderabad, India.
authors.forename: P S
authors.initials: PS
authors.lastname: Vali
authors.affiliation: Department of Nephrology, Osmania General Hospital and Medical College, Telangana, Hyderabad, India.
authors.forename: K
authors.initials: K
authors.lastname: Ismal
authors.affiliation: Department of Pathology, Apollo Hospital, Telangana, Hyderabad, India.
authors.forename: S
authors.initials: S
authors.lastname: Gowrishankar
authors.affiliation: Department of Pathology, Apollo Hospital, Telangana, Hyderabad, India.
authors.forename: M D
authors.initials: MD
authors.lastname: Padua
authors.affiliation: Department of Pathology, Apollo Hospital, Telangana, Hyderabad, India.
authors.forename: M
authors.initials: M
authors.lastname: Swain
keywords: Corneal deposits; lecithin cholesterol acyl transferase; nephrotic syndrome; renal foam cells