title: Major Cardiac Events After Non-cardiac Surgery.
abstract: Postoperative cardiovascular complications might be difficult to assess and are known to be associated with longer hospital stay and increased costs as well as higher morbidity and mortality rates. The aim of this study was to evaluate the predictors for major cardiac events (MCE) after non-cardiac surgery.
  
  
  
  The study included 4398 patients who were admitted to the Surgical Intensive Care Unit between January 1, 2006 and July 19, 2013. Acute physiology and chronic health evaluation II score and simplified acute physiology score (SAPS II) were calculated, and all variables entered as parameters were evaluated independently. Multivariate logistic regression analysis was performed to assess the independent factors for MCE.
  
  
  
  A total of 107 people experienced MCE. The independent predictors for postoperative MCE were higher fraction of inspired oxygen (FiO2) (odds ratio [OR] 38.97; 95 % confidence interval [CI] 10.81-140.36), history of ischemic heart disease (OR 3.38; 95 % CI 2.12-5.39), history of congestive heart disease (OR 2.39; 95 % CI 1.49-3.85), history of insulin therapy for diabetes (OR 2.93; 95 % CI 1.66-5.19), and increased SAPS II (OR 1.03; 95 % CI 1.01-1.05). Having a MCE was associated with a longer length of stay in the surgical intensive care unit (OR 1.01, 95 % CI 1.00-1.01).
  
  
  
  FiO2, ischemic heart disease, congestive heart disease, insulin therapy for diabetes, SAPS II, and length of stay in the surgical intensive care unit were independent predictors for MCE.
authors.affiliation: Department of Anesthesiology, Hospital de São João, Porto, Portugal.
authors.forename: Gabriela
authors.initials: G
authors.lastname: Sousa
authors.affiliation: Department of Anesthesiology, Hospital de São João, Porto, Portugal.
authors.forename: Ana
authors.initials: A
authors.lastname: Lopes
authors.affiliation: Department of Anesthesiology, Hospital de São João, Porto, Portugal.
authors.forename: Pedro
authors.initials: P
authors.lastname: Reis
authors.affiliation: Department of Anesthesiology, Hospital de São João, Porto, Portugal.
authors.forename: Vasco
authors.initials: V
authors.lastname: Carvalho
authors.affiliation: Department of Anesthesiology, Hospital de São João, Porto, Portugal.
authors.forename: Alice
authors.initials: A
authors.lastname: Santos
authors.affiliation: Department of Anesthesiology, Hospital de São João, Porto, Portugal. fernando.abelha@gmail.com.|Department of Anesthesiology and Perioperative Medicine, Faculty of Medicine, University of Porto, Porto, Portugal. fernando.abelha@gmail.com.
authors.forename: Fernando José
authors.identifier: 0000-0002-2805-2908
authors.initials: FJ
authors.lastname: Abelha
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000209:etiology*; D005260:Female; D006331:Heart Diseases / Q000150:complications; D006801:Humans; D007004:Hypoglycemic Agents / Q000009:adverse effects; D007328:Insulin / Q000009:adverse effects; D007362:Intensive Care Units; D007902:Length of Stay / Q000706:statistics & numerical data; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D016017:Odds Ratio; D011183:Postoperative Complications; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D013514:Surgical Procedures, Operative / Q000009:adverse effects*; D013997:Time Factors
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin