title: Influenza Vaccination and Other Factors Related to the Development of Influenza-Like Illness Among Patients on Chronic Hemodialysis in a Japanese Dialysis Facility.
abstract: The present study was conducted to evaluate the protective effect of seasonal influenza vaccination on the development of influenza-like illness (ILI), as well as to investigate factors related to the development of ILI among patients in a Japanese dialysis facility. One hundred eighty-three hemodialysis (HD) patients were followed up from November 2008 to March 2009. During the follow-up period, 17 patients developed ILI. We compared the characteristics of these 17 patients to patients without ILI. Compared to the non-ILI group (N = 166), the ILI group (N = 17) showed a non-significantly lower rate of influenza vaccination (70.6% vs. 86.7%, P = 0.07), while any other factor did not differ between the two groups. Influenza vaccination tended to reduce the risk of ILI (Odds ratio = 0.37, 95% CI = 0.12 to 1.14, P = 0.07). The findings of the present study suggested that the influenza vaccine was 60% effective to prevent ILI among HD patients, although the effectiveness was not statistically significant.
authors.affiliation: Department of Community Health and Clinical Epidemiology, St. Mary's College, Kurume, Japan.|Division of Nephrology, St. Mary's Hospital, Kurume, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Washio
authors.affiliation: Division of Nephrology, St. Mary's Hospital, Kurume, Japan.
authors.forename: Harumichi
authors.initials: H
authors.lastname: Higashi
authors.affiliation: Division of Nephrology, St. Mary's Hospital, Kurume, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Sugawara
authors.affiliation: Graduate School of Nursing Science, St. Mary's College, Kurume, Japan.
authors.forename: Chiyo
authors.initials: C
authors.lastname: Tsusumi
authors.affiliation: Graduate School of Nursing Science, St. Mary's College, Kurume, Japan.
authors.forename: Mayumi
authors.initials: M
authors.lastname: Sakita
authors.affiliation: Department of Community Health and Clinical Epidemiology, St. Mary's College, Kurume, Japan.|Graduate School of Nursing Science, St. Mary's College, Kurume, Japan.
authors.forename: Yuichiro
authors.initials: Y
authors.lastname: Ide
authors.affiliation: Department of Integrated Therapy for Chronic Kidney Disease, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Tsuruya
authors.affiliation: Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Takanari
authors.initials: T
authors.lastname: Kitazono
authors.affiliation: Department of Public Health, Osaka City University Graduate School of Medical Science, Osaka, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Kondo
authors.affiliation: Department of Community Health and Clinical Epidemiology, St. Mary's College, Kurume, Japan.|Graduate School of Nursing Science, St. Mary's College, Kurume, Japan.
authors.forename: Saburo
authors.initials: S
authors.lastname: Ide
mesh_terms: D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007252:Influenza Vaccines / Q000008:administration & dosage*; D007251:Influenza, Human / Q000453:epidemiology* / Q000517:prevention & control; D007564:Japan; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D014611:Vaccination / Q000706:statistics & numerical data*
chemical_list: D007252:Influenza Vaccines
keywords: Chronic renal failure; Effectiveness; Hemodialysis; Influenza vaccine; Japan