title: Gabapentin induces edema, hyperesthesia and scaling in a depressed patient; a diagnostic challenge.
abstract: Gabapentin is a common drug used as analgesic and anticonvulsant and also is prescribed for insomnia, depression, obsessive - compulsive disorder and panic attack. We report a case of a 48-year-old man who is prescribed gabapentin because of insomnia, headache, and depressed mood. In the first period of using the drug no complication has been seen. However in the next period, side-effects such as hyperesthesia, scaling and severe localized edema has been observed. After several laboratory tests and imaging, no reason was found for his edema. And after discontinuing gabapentin the pain and edema was quite relieved. We found out the brand of the drug has been switched in the second stage. The point which makes our study special is the incidence of side-effects such as severe edema, scaling and hyperesthesia for the first time because of using gabapentin and changing the drug combination.
authors.affiliation: Department of Psychiatry, Research Center of Addiction and Behavioral Sciences, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Bidaki
authors.affiliation: Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Sadeghi
authors.affiliation: Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Safiye
authors.initials: S
authors.lastname: Shafizadegan
authors.affiliation: Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Sadeghi
authors.affiliation: Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Behrang
authors.initials: B
authors.lastname: Khalili
authors.affiliation: Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Haghshenas
authors.affiliation: Department of Neurosurgery, Isfahan University of Medical Sciences, Isfahan, Iran.
authors.forename: Seyyed Mohammad Mahdy
authors.initials: SM
authors.lastname: Mirhosseini
keywords: Edema; gabapentin; hyperesthesia; scaling; side-effect