title: A Convenient Palladium-Catalyzed Reductive Carbonylation of Aryl Iodides with Dual Role of Formic Acid.
abstract: Palladium-catalyzed reductive carbonylation of aryl halides represents a straightforward pathway for the synthesis of aromatic aldehydes. The known reductive carbonylation procedures either require CO gas or complexed compounds as CO sources. In this communication, we developed a palladium-catalyzed reductive carbonylation of aryl iodides with formic acid as the formyl source. As a convenient, practical, and environmental friendly methodology, no additional silane or H2 was required. A variety of aromatic aldehydes were isolated in moderate to excellent yields under mild reaction conditions. Notably, this is the first procedure on using formic acid as the formyl source.
authors.affiliation: Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, 310018, People's Republic of China.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Qi
authors.affiliation: Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, 310018, People's Republic of China.
authors.forename: Chong-Liang
authors.initials: CL
authors.lastname: Li
authors.affiliation: Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, 310018, People's Republic of China. xiao-feng.wu@catalysis.de.|Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany. xiao-feng.wu@catalysis.de.
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Wu
keywords: CO source; aromatic aldehydes; formic acid; palladium; synthetic methods