title: Osteoporosis in Gastrointestinal Diseases.
abstract: Secondary osteoporosis occurs as an isolated pathology or co-exists with types I and II osteoporosis. The gastroenterologist may come across osteoporosis or osteopenia in a patient with a gastrointestinal disease. This is often a young patient in whom investigations should be carried out and appropriate treatment initiated, aimed at preventing bone fractures and the formation of the best peak bone mass. Osteoporosis occurs in patients with the following conditions: Crohn's disease, ulcerative colitis, celiac disease, post gastrectomy patients, patients with short bowel syndrome, chronic hepatitis and cirrhosis, treated with steroids (steroid-induced osteoporosis) and patients using proton pump inhibitors chronically (state of achlorhydria). It is therefore necessary to approve a list of risk factors of secondary osteoporosis, the presence of which would be an indication for screening for osteoporosis, including a DXA study and the development of a separate algorithm for the therapeutic management of secondary osteoporosis accompanying gastrointestinal diseases, especially in premenopausal young women and young men, because there are currently no registered drugs with proven antifracture activity for this group of patients.
authors.affiliation: Department of Gastroenterology, Human Nutrition and Internal Diseases, Poznan University of Medical Sciences, Poland.
authors.forename: Iwona
authors.initials: I
authors.lastname: Krela-Kaźmierczak
authors.affiliation: Department of Gastroenterology, Human Nutrition and Internal Diseases, Poznan University of Medical Sciences, Poland.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Szymczak
authors.affiliation: Department of Gastroenterology, Human Nutrition and Internal Diseases, Poznan University of Medical Sciences, Poland.
authors.forename: Liliana
authors.initials: L
authors.lastname: Łykowska-Szuber
authors.affiliation: Department of Gastroenterology, Human Nutrition and Internal Diseases, Poznan University of Medical Sciences, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Eder
authors.affiliation: Department of Gastroenterology, Human Nutrition and Internal Diseases, Poznan University of Medical Sciences, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Linke
mesh_terms: D015502:Absorptiometry, Photon; D000465:Algorithms; D019091:Critical Pathways; D005743:Gastrectomy / Q000009:adverse effects; D005767:Gastrointestinal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D005938:Glucocorticoids / Q000009:adverse effects; D006801:Humans; D010024:Osteoporosis / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy; D011237:Predictive Value of Tests; D011379:Prognosis; D054328:Proton Pump Inhibitors / Q000009:adverse effects; D018570:Risk Assessment; D012307:Risk Factors
chemical_list: D005938:Glucocorticoids; D054328:Proton Pump Inhibitors