title: Low Grip Strength and Prediabetes in Normal-Weight Adults.
abstract: BACKGROUND
  Detection of prediabetes is an important step in diabetes prevention in primary care. Risk stratification of healthy-weight individuals for detection of prediabetes is necessary to avoid missed opportunities for diabetes prevention.
  
  
  METHODS
  Using data from the 2011 to 2012 National Health and Nutrition Examination Survey, we studied the relationship between combined handgrip strength, a proxy for lean muscle mass, and prediabetes among adults aged ≥20 years without diagnosed or undiagnosed diabetes who had a healthy body mass index (18.5-24.9 kg/m(2); unweighted n = 1340, weighted n = 58,360,690). Prediabetes was defined as having a glycohemoglobin level between 5.7% and 6.4%.
  
  
  RESULTS
  Of the healthy-weight adults, 20.5% had prediabetes. Combined mean grip strength was lower for individuals with prediabetes than those with normoglycemia in the full sample (63.8 vs 70.9 kg; P = .004). Similar results were seen among both men (87.9 vs 82.1 kg; P = .03) and women (51.8 vs 56.5 kg; P = .001) in subgroup analysis.
  
  
  CONCLUSIONS
  Grip strength is associated with prediabetes among healthy-weight US adults. Grip strength may have utility as an indicator for screening healthy-weight individuals for prediabetes.
authors.affiliation: From the Department of Health Services Research, Management, and Policy, University of Florida, Gainesville (AGM, AJ); the Department of Family and Community Medicine, University of Florida, Gainesville (AGM, RJT); and the Department of Aging and Geriatric Research, University of Florida, Gainesville (SDA). arch.mainous@ufl.edu.
authors.forename: Arch G
authors.initials: AG
authors.lastname: Mainous
authors.affiliation: From the Department of Health Services Research, Management, and Policy, University of Florida, Gainesville (AGM, AJ); the Department of Family and Community Medicine, University of Florida, Gainesville (AGM, RJT); and the Department of Aging and Geriatric Research, University of Florida, Gainesville (SDA).
authors.forename: Rebecca J
authors.initials: RJ
authors.lastname: Tanner
authors.affiliation: From the Department of Health Services Research, Management, and Policy, University of Florida, Gainesville (AGM, AJ); the Department of Family and Community Medicine, University of Florida, Gainesville (AGM, RJT); and the Department of Aging and Geriatric Research, University of Florida, Gainesville (SDA).
authors.forename: Stephen D
authors.initials: SD
authors.lastname: Anton
authors.affiliation: From the Department of Health Services Research, Management, and Policy, University of Florida, Gainesville (AGM, AJ); the Department of Family and Community Medicine, University of Florida, Gainesville (AGM, RJT); and the Department of Aging and Geriatric Research, University of Florida, Gainesville (SDA).
authors.forename: Ara
authors.initials: A
authors.lastname: Jo
mesh_terms: D000328:Adult; D000367:Age Factors; D015992:Body Mass Index; D003920:Diabetes Mellitus / Q000517:prevention & control*; D005260:Female; D006442:Glycated Hemoglobin / Q000032:analysis*; D018737:Hand Strength; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D011236:Prediabetic State / Q000097:blood / Q000175:diagnosis*; D012307:Risk Factors; D055815:Young Adult
chemical_list: D006442:Glycated Hemoglobin
keywords: Hand Strength; Prediabetes