title: Complete Penile Necrosis in a Patient With Heparin-induced Thrombocytopenia: A Case Report.
abstract: Penile necrosis is a rare condition that has been mostly described in association with diabetes mellitus and end-stage renal disease. We report an unusual case of acute penile necrosis because of heparin-induced thrombocytopenia. A 75-year-old man presented with acute renal failure and experienced cardiac complications during the hospitalization. The patient was treated twice with intravenous heparin. He developed symptoms of penile necrosis 4 days after the reintroduction of heparin. At that moment, the platelet count dropped by 61%, and the analysis of heparin-pf4 antibodies was positive for heparin-induced thrombocytopenia. The patient underwent a total penectomy and a perineal urethrostomy.
authors.affiliation: Division of Urology, Centre Hospitalier Universitaire de Québec (CHU), Université Laval, Québec City, Québec, Canada.
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Blais
authors.affiliation: Division of Urology, Centre Hospitalier Universitaire de Québec (CHU), Université Laval, Québec City, Québec, Canada.
authors.forename: Marie-Pier
authors.initials: MP
authors.lastname: Deschênes Rompré
authors.affiliation: Division of Urology, Centre Hospitalier Universitaire de Québec (CHU), Université Laval, Québec City, Québec, Canada.
authors.forename: Louis
authors.initials: L
authors.lastname: Lacombe
keywords: Heparin; Necrosis; Penis; Thrombocytopenia