title: Sensorimotor Peripheral Nerve Function and Physical Activity in Older Men.
abstract: We determined whether sensorimotor peripheral nerve (PN) function was associated with physical activity (PA) in older men. The Osteoporotic Fractures in Men Study Pittsburgh, PA, site (n = 328, age 78.8 ± 4.7 years) conducted PN testing, including: peroneal motor and sural sensory nerve conduction (latencies, amplitudes: CMAP and SNAP for motor and sensory amplitude, respectively), 1.4g/10g monofilament (dorsum of the great toe), and neuropathy symptoms. ANOVA and multivariate linear regression modeled PN associations with PA (Physical Activity Scale for the Elderly [PASE] and SenseWear Armband). After multivariable adjustment, better motor latency was associated with higher PASE scores (160.5 ± 4.8 vs. 135.6 ± 6.7, p < .01). Those without versus with neuropathy symptoms had higher PASE scores (157.6 ± 5.3 vs. 132.9 ± 7.1, p < .01). Better versus worse SNAP was associated with slightly more daily vigorous activity (9.5 ± 0.8 vs. 7.3 ± 0.7, p = .05). Other PN measures were not associated with PA. Certain PN measures were associated with lower PA, suggesting a potential pathway for disability.
authors.forename: Brittney S
authors.initials: BS
authors.lastname: Lange-Maia
authors.forename: Jane A
authors.initials: JA
authors.lastname: Cauley
authors.forename: Anne B
authors.initials: AB
authors.lastname: Newman
authors.forename: Robert M
authors.initials: RM
authors.lastname: Boudreau
authors.forename: John M
authors.initials: JM
authors.lastname: Jakicic
authors.forename: Nancy W
authors.initials: NW
authors.lastname: Glynn
authors.forename: Sasa
authors.initials: S
authors.lastname: Zivkovic
authors.forename: Thuy-Tien L
authors.initials: TL
authors.lastname: Dam
authors.forename: Paolo
authors.initials: P
authors.lastname: Caserotti
authors.forename: Peggy M
authors.initials: PM
authors.lastname: Cawthon
authors.forename: Eric S
authors.initials: ES
authors.lastname: Orwoll
authors.forename: Elsa S
authors.initials: ES
authors.lastname: Strotmeyer
mesh_terms: D061725:Accelerometry; D000368:Aged; D004734:Energy Metabolism / Q000502:physiology; D015444:Exercise / Q000502:physiology*; D015577:Geriatric Assessment; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009431:Neural Conduction / Q000502:physiology; D010525:Peripheral Nerves / Q000502:physiology*; D010543:Peroneal Nerve / Q000502:physiology; D013497:Sural Nerve / Q000502:physiology
keywords: aging; motor peripheral nerve; sensory peripheral nerve