title: Tissue oximetry in anaesthesia and intensive care.
abstract: Conventional monitoring during surgery and intensive care is not sufficiently sensitive to detect acute changes in vital organs perfusion, while its good quality is critical for maintaining their function. Disturbed vital organ perfusion may lead to the development of postoperative complications, including neurological sequel and renal failure. Near-infra-red spectroscopy (NIRS) represents one of up-to-date techniques of patient monitoring which is commonly used for the assessment of brain oximetry in thoracic aorta surgery, and - increasingly more often -in open-heart surgery. Algorithms for maintaining adequate brain saturation may result in a decrease of neurological complications and cognitive dysfunction following cardiac surgery. The assessment of kidney and visceral perfusion with tissue oximetry is gaining increasing interest during pediatric cardiac surgery. Attempts at decreasing complications by the use of brain oximetry during carotid endarterectomy, as well as thoracic and abdominal surgery demonstrated conflicting results. In recent years NIRS technique was proposed as a tool for muscle perfusion assessment under short term ischemia and reperfusion, referred to as vascular occlusion test (VOT). This monitoring extension allows for the identification of early disturbances in tissue perfusion. Results of recent studies utilizing VOT suggest that the muscle saturation decrease rate is reduced in septic shock patients, while decreased speed of saturation recovery on reperfusion is related to disturbed microcirculation. Being non-invasive and feasible technique, NIRS offers an improvement of preoperative risk assessment in cardiac surgery and promises more comprehensive intraoperative and ICU patient monitoring allowing for better outcome.
authors.affiliation: Department of Anaesthesiology and Intensive Therapy, University Clinical Centre in Gdańsk, Poland. biedrzycka.ola@gmail.com.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Biedrzycka
authors.forename: Romuald
authors.initials: R
authors.lastname: Lango
mesh_terms: D000758:Anesthesia; D001921:Brain / Q000378:metabolism*; D006348:Cardiac Surgical Procedures; D003422:Critical Care; D006801:Humans; D008833:Microcirculation; D016343:Monitoring, Intraoperative; D010092:Oximetry; D010100:Oxygen / Q000378:metabolism*; D019265:Spectroscopy, Near-Infrared / Q000379:methods*
chemical_list: D010100:Oxygen
keywords: brain saturation; stroke; tissue oximetry