title: Toward an Integrated Zebrafish Health Management Program Supporting Cancer and Neuroscience Research.
abstract: Zebrafish is already one of the most used model organisms in biomedical sciences and other research fields. It is therefore becoming increasingly important to assure that zebrafish maintained in laboratory aquaculture conditions are raised and housed under rigorous standards that promote health and welfare to guarantee the required quality and reproducibility of research data. Specifying the programs each facility is adopting would be the first step to achieve this by allowing other facilities to compare, improve, and discuss their protocols and fish performance. We provide in this article a detailed description of an integrated facility health management program, with protocols and readouts, fully designed and aimed at maximizing fish health, welfare, and performance for research.
authors.affiliation: 1 Champalimaud Centre for the Unknown , Lisbon, Portugal .
authors.forename: Sandra
authors.initials: S
authors.lastname: Martins
authors.affiliation: 1 Champalimaud Centre for the Unknown , Lisbon, Portugal .
authors.forename: Joana F
authors.initials: JF
authors.lastname: Monteiro
authors.affiliation: 1 Champalimaud Centre for the Unknown , Lisbon, Portugal .
authors.forename: Maria
authors.initials: M
authors.lastname: Vito
authors.affiliation: 2 Fulcrum Automation & Control Technologies , Beachwood, Ohio.
authors.forename: David
authors.initials: D
authors.lastname: Weintraub
authors.affiliation: 1 Champalimaud Centre for the Unknown , Lisbon, Portugal .
authors.forename: Joana
authors.initials: J
authors.lastname: Almeida
authors.affiliation: 1 Champalimaud Centre for the Unknown , Lisbon, Portugal .
authors.forename: Ana Catarina
authors.initials: AC
authors.lastname: Certal
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D017756:Aquaculture; D005160:Facility Design and Construction; D008495:Medical Oncology; D009369:Neoplasms; D009488:Neurosciences; D012106:Research; D015027:Zebrafish