title: Borna disease virus and deficit schizophrenia.
abstract: BACKGROUND
  It is controversial whether Borna disease virus (BDV) infects humans and causes psychiatric disorders.
  
  
  OBJECTIVE
  The relationship between BDV infection and schizophrenia with deficit syndrome was investigated.
  
  
  METHODS
  Using the Schedule for the Deficit Syndrome, 62 schizophrenic in-patients were selected from three psychiatric hospitals. RNA was extracted from peripheral blood mononuclear cells and analyzed using nested reverse transcriptase-polymerase chain reaction with primers to detect BDV p24 and p40.
  
  
  CONCLUSIONS
  BDV transcripts were not detected in samples from any of the 62 schizophrenic patients. These data do not support an etiologic association between BDV infection and the deficit form of schizophrenia.
authors.affiliation: 1Department of Psychiatry.
authors.forename: Yong-Ku
authors.initials: YK
authors.lastname: Kim
authors.affiliation: 2Department of Microbiology, Institute for Viral Diseases, College of Medicine, Korea University, Seoul.
authors.forename: Sang-Hyun
authors.initials: SH
authors.lastname: Kim
authors.affiliation: 1Department of Psychiatry.
authors.forename: Chang-Su
authors.initials: CS
authors.lastname: Han
authors.affiliation: 1Department of Psychiatry.
authors.forename: Heon-Jeong
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: 3Yong-In Mental Hospital, Yong-In Institute, Kyunggido.
authors.forename: Hyung-Seob
authors.initials: HS
authors.lastname: Kim
authors.affiliation: 4Keyo Mental Hospital.
authors.forename: Sung-Chul
authors.initials: SC
authors.lastname: Yoon
authors.affiliation: 5Department of Psychiatry, College of Medicine, The Catholic University, Seoul, Korea.
authors.forename: Dai-Jin
authors.initials: DJ
authors.lastname: Kim
authors.affiliation: 2Department of Microbiology, Institute for Viral Diseases, College of Medicine, Korea University, Seoul.
authors.forename: Ki-Joon
authors.initials: KJ
authors.lastname: Song
authors.affiliation: 6Department of Psychiatry, University of Maastricht, Maastricht, the Netherlands.
authors.forename: Michael
authors.initials: M
authors.lastname: Maes
authors.affiliation: 2Department of Microbiology, Institute for Viral Diseases, College of Medicine, Korea University, Seoul.
authors.forename: Jin-Won
authors.initials: JW
authors.lastname: Song