title: Safety and efficacy of a novel short occlusive regimen of imiquimod for selected non-melanotic skin lesions in renal transplant patients.
abstract: Australian patients remain at very high risk of non-melanotic skin cancer after renal transplantation. Surgical excision offers a cure but destroys tissue and may jeopardise function and cosmesis. We report excellent safety and efficacy using topical imiquimod in a novel short intensive regimen in 10 renal transplant patients with superficial basal cell carcinomas, Bowen disease or actinic keratosis. Outcomes compare well to those reported with extended-use imiquimod protocols.
authors.affiliation: Department of Nephrology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
authors.forename: G
authors.initials: G
authors.lastname: Das
authors.affiliation: Department of Dermatology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Tan
authors.affiliation: Department of Nephrology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.|Department of Medicine, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Nicholls
mesh_terms: D000328:Adult; D000368:Aged; D000634:Aminoquinolines / Q000008:administration & dosage* / Q000009:adverse effects*; D000970:Antineoplastic Agents / Q000008:administration & dosage* / Q000009:adverse effects*; D001315:Australia / Q000453:epidemiology; D005260:Female; D006801:Humans; D000077271:Imiquimod; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000634:Aminoquinolines; D000970:Antineoplastic Agents; D000077271:Imiquimod
keywords: BCC; Bowen disease; actinic keratoses; imiquimod; non-melanotic skin cancer; renal transplant