title: A biomechanical model of the wrist joint for patient-specific model guided surgical therapy: Part 2.
abstract: An enhanced musculoskeletal biomechanical model of the wrist joint is presented in this article. The computational model is based on the multi-body simulation software AnyBody. Multi body dynamic musculoskeletal models capable of predicting muscle forces and joint contact pressures simultaneously would be valuable for studying clinical issues related to wrist joint degeneration and restoration. In this study, the simulation model of the wrist joint was used for investigating deeper the biomechanical function of the wrist joint. In representative physiological scenarios, the joint behavior and muscle forces were computed. Furthermore, the load transmission of the proximal wrist joint was investigated. The model was able to calculate the parameters of interest that are not easily obtainable experimentally, such as muscle forces and proximal wrist joint forces. In the case of muscle force investigation, the computational model was able to accurately predict the computational outcome for flexion and extension motion. In the case of force distribution of the proximal wrist joint, the model was able to predict accurately the computational outcome for an axial load of 140 N. The presented model and approach of using a multi-body simulation model are anticipated to have value as a predictive clinical tool including effect of injuries or anatomical variations and initial outcome of surgical procedures for patient-specific planning and custom implant design. Therefore, patient-specific multi-body simulation models are potentially valuable tools for surgeons in pre- and intraoperative planning of implant placement and orientation.
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany Department of Orthopaedic, University Hospital Aachen, RWTH Aachen University, Aachen, Germany eschweiler@hia.rwth-aachen.de.
authors.forename: Jörg
authors.initials: J
authors.lastname: Eschweiler
authors.affiliation: Department of Plastic Surgery, Hand and Burns Surgery, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: Jan-Philipp
authors.initials: JP
authors.lastname: Stromps
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany.
authors.forename: Maximilian
authors.initials: M
authors.lastname: Fischer
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany.
authors.forename: Fabian
authors.initials: F
authors.lastname: Schick
authors.affiliation: Department of Orthopaedic, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Rath
authors.affiliation: Department of Plastic Surgery, Hand and Burns Surgery, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: Norbert
authors.initials: N
authors.lastname: Pallua
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Radermacher
mesh_terms: D001696:Biomechanical Phenomena / Q000502:physiology; D003198:Computer Simulation; D006801:Humans; D008954:Models, Biological; D016059:Range of Motion, Articular / Q000502:physiology; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014955:Wrist Joint / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology / Q000601:surgery
keywords: Wrist joint; biomechanics; computational model; multi-body simulation; therapy planning