title: Multifocal extramammary Paget's disease-associated adenocarcinoma: a rare condition of flexoral skin of multiple sites.
abstract: Extramammary Paget disease (EMPD) is a rare malignant neoplasm of apocrine sweat glands that is morphologically and histologically identical to Paget disease of the breast. The primary lesion is usually a solitary, well-demarcated, erythematous, scaly plaque that may contain crust, erosions, or ulcerations. The vulva is the most common site, but any area containing apocrine sweat glands may be involved. We present a case of triple extramammary Paget disease of the groin and bilateral axillae in a diabetic patient whose axillary lesions appeared consistent with acanthosis nigricans. This case demonstrates the need to consider EMPD in the evaluation of acanthosis of the axilla given its ability to mimic more common conditions.
authors.affiliation: University of Texas Health Science Center at Houston.
authors.forename: Kristin
authors.initials: K
authors.lastname: Wolf
authors.forename: Larissa
authors.initials: L
authors.lastname: Stewart
authors.forename: Ronald
authors.initials: R
authors.lastname: Rapini
authors.forename: Kudakwashe
authors.initials: K
authors.lastname: Mutyambizi
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis*; D001706:Biopsy; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D010145:Paget Disease, Extramammary / Q000175:diagnosis*; D035583:Rare Diseases; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000175:diagnosis*