title: Myoblastoma of the breast: Our experience and review of literature.
abstract: BACKGROUND
  Breast myoblastoma or granular cell tumor involving the breast parenchyma has been described in detail for the first time since Abrikossoff in 1931. The location of this injury to the breast is very rare, accounting for between 5% and 15% of all cases of cancer of the granular cells. We present our experience regarding the identification of two cases because of the relative rarity of this tumor. It is often confused with breast cancer on clinical and radiological, and its diagnosis can then be difficult for physicians, radiologists and pathologists.
  
  
  METHODS
  We report the cases of two young women who came to our attention because of the presence of mass shoveled breast, mobile and accompanied by pain cycle independent. In both cases, mammography and ultrasound revealed the presence of heterogeneous mass and irregular, but in one of two such mass located at the Union of external quadrants of the left breast and was in contact with his serratus anterior and suspicion for malignancy. In both cases the 'histology combined with immunohistochemical study proved to be a granular cell tumor.
  
  
  CONCLUSIONS
  Although a granular cell tumor of the breast is a rare tumor breast, should be considered in the differential diagnosis of benign and malignant lesions. Surgeons and pathologists should keep in mind when considering a granular cell tumor cells with abundant granular cytoplasm containing materials to avoid misdiagnosing breast cancer, which could lead to unnecessary surgery.
authors.affiliation: S. Maria University Hospital, Terni, Italy. Electronic address: alessandrosanguinetti@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Sanguinetti
authors.affiliation: University of Perugia, Italy. Electronic address: apolis74@yahoo.it.
authors.forename: A
authors.initials: A
authors.lastname: Polistena
authors.affiliation: S. Maria University Hospital, Terni, Italy. Electronic address: robertalucchini@alice.it.
authors.forename: R
authors.initials: R
authors.lastname: Lucchini
authors.affiliation: Perugia University Hospital, Italy. Electronic address: massimo.monacelli@gmail.com.
authors.forename: M
authors.initials: M
authors.lastname: Monacelli
authors.affiliation: University of Perugia, Italy. Electronic address: sergio.galasse@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Galasse
authors.affiliation: Medical School University of Perugia, Italy. Electronic address: stefano_avenia@libero.it.
authors.forename: S
authors.initials: S
authors.lastname: Avenia
authors.affiliation: University of Perugia, Italy. Electronic address: walterbugiantella@alice.it.
authors.forename: W
authors.initials: W
authors.lastname: Bugiantella
authors.affiliation: S. Maria University Hospital, Terni, Italy. Electronic address: triolaroberta@gmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Triola
authors.affiliation: University of Perugia, Italy. Electronic address: rondellif@hotmail.com.
authors.forename: R
authors.initials: R
authors.lastname: Cirocchi
authors.affiliation: University of Perugia, Italy. Electronic address: rondellif@hotmail.com.
authors.forename: F
authors.initials: F
authors.lastname: Rondelli
authors.affiliation: University of Perugia, Italy. Electronic address: nicolaavenia@libero.it.
authors.forename: N
authors.initials: N
authors.lastname: Avenia
keywords: Breast myoblastoma; Diagnosis; Immunohistochemistry; Surgery