title: Building Ancestral Recombination Graphs for Whole Genomes.
abstract: We propose a heuristic algorithm, called ARG4WG, to build plausible ancestral recombination graphs (ARGs) from thousands of whole genome samples. By using the longest shared end for recombination inference, ARG4WG constructs ARGs with small numbers of recombination events that perform well in association mapping on genome-wide association studies.
authors.forename: Thao Thi Phuong
authors.initials: TT
authors.lastname: Nguyen
authors.forename: Vinh Sy
authors.initials: VS
authors.lastname: Le
authors.forename: Hai Bich
authors.initials: HB
authors.lastname: Ho
authors.forename: Quang
authors.initials: Q
authors.lastname: Si Le
mesh_terms: D000465:Algorithms; D030541:Databases, Genetic; D005828:Genetics, Population; D055106:Genome-Wide Association Study / Q000379:methods*; D023281:Genomics / Q000379:methods*; D006801:Humans; D008957:Models, Genetic; D011995:Recombination, Genetic / Q000235:genetics*