title: From syncope episode to the diagnosis of ovarian dermoid cyst associated with a cystadenoma.
abstract: Ovarian teratoma has various presentations. We present a 28-year female diagnosed with a tumour after a fainting episode. Medical history was non-contributory except for mild intermittent pelvic pain. Cardiologic and neurological evaluation found no cause of syncope. Abdominal ultrasound revealed a right ovarian tumour that was laparoscopically removed. The menses continued to be normal. The pathological exam showed an encapsulated tumour of 8 cm with hair and small bone parts (mature teratoma with a cystadenoma). Immunohistochemistry was positive for CK34beta E12 in stratified squamous epithelium of skin glands; positive CK7 in kidney tubular parts; positive actin in smooth muscle. The endocrine profile was normal and the patient remained asymptomatic. The challenging in the pathological report was to differentiate a cystic part of a solid tumour to a teratoma associated cystadenoma. No apparent cause of syncope was found so a possible tumour related local pain and inflammation mechanism might be involved.
authors.affiliation: Department of Cellular and Molecular Medicine, Romania.
authors.forename: Ancuta Augustina
authors.initials: AA
authors.lastname: Gheorghisan-Galateanu
authors.affiliation: Departement of Endocrinology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania & C.I. Parhon National Institute of Endocrinology, Bucharest, Romania.
authors.forename: Mara
authors.initials: M
authors.lastname: Carsote
authors.affiliation: Department of Imagery, C.I.Parhon National Institute of Endocrinology, Bucharest, Romania.
authors.forename: Anda
authors.initials: A
authors.lastname: Dumitrascu
authors.affiliation: Department of Endocrinology, Medcenter, Bucharest, 5Department of Pathology, C.I.Parhon National Institute of Endocrinology, Bucharest, Romania & Monza Oncoteam Hospital, Bucharest, Romania.
authors.forename: Andreea
authors.initials: A
authors.lastname: Geleriu
authors.affiliation: Department of Pathology, C.I.Parhon National Institute of Endocrinology, Bucharest, Romania & Monza Oncoteam Hospital, Bucharest, Romania.
authors.forename: Dana
authors.initials: D
authors.lastname: Terzea
authors.affiliation: Department of Endocrinology, C.I.Parhon National Institute of Endocrinology, Bucharest, Romania & Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
authors.forename: Catalina
authors.initials: C
authors.lastname: Poiana
mesh_terms: D000328:Adult; D003537:Cystadenoma / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D033162:Incidental Findings; D008279:Magnetic Resonance Imaging; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging* / Q000473:pathology; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D013575:Syncope / Q000175:diagnosis*; D013724:Teratoma / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D014463:Ultrasonography
keywords: Ovarian teratoma, Dermoid cyst, Syncope, Cystadenoma.