title: Estimation of postmortem interval using the data of insulin level in the cadaver׳s blood.
abstract: An assessment of levels of Insulin in cadaveric fluids, to estimate the postmortem interval (PMI) was carried out. To profile postmortem changes of Insulin, it was extracted at different intervals i.e. (0, 3, 6, 12, 24 h), from the heart of 22 human cadavers. The cases included were the subjects of accidental deaths without any prior history of disease and their exact time of death was known. Immunoanalyzer Cobas e-411 instrument was used to detect the relationship between the amount of Insulin and PMI. Level of Insulin was measured in cardiac blood. Statically, significant correlations between levels of Insulin and PMI were studied and correlation coefficients were calculated. SPSS (version 12.0) was used for statistical analysis. Insulin levels in cadaver blood are correlated significantly with PMI with a p value of <0.001. When insulin level increases by 1 unit the duration decreases by 0.93 units. The least square regression line is: [Duration(Y)=22.71-0.93 Insulin level (X)].
authors.affiliation: Post Graduate Department of Pathology, K.G. Medical University, Lucknow, UP, India.
authors.forename: Sachil
authors.initials: S
authors.lastname: Kumar
authors.affiliation: Department of Forensic Medicine & Toxicology, K.G. Medical University, Lucknow, UP, India.
authors.forename: Anoop K
authors.initials: AK
authors.lastname: Verma
keywords: Blood; Cadavers; Insulin; Post-mortem interval