title: Screening First Degree Relatives of Persons with Primary Open Angle Glaucoma in India.
abstract: OBJECTIVE
  To report the results of screening first degree relatives of persons identified with primary open angle glaucoma in a tertiary eye hospital glaucoma services.
  
  
  METHODS
  A cross-sectional study of first degree relatives of persons with primary open angle glaucoma.
  
  
  METHODS
  First degree relatives of patients identified with primary open angle glaucoma were invited to participate in a screening evaluation in the base hospital to detect glaucoma. All participating individuals had comprehensive eye examination including vision screening, refraction, slit-lamp biomicroscopy, applanation tonometry, gonioscopy, frequency doubling peri-metry and dilated fundus examination. Persons with definite and suspected glaucoma were subject to full threshold automated perimetry.
  
  
  RESULTS
  A 514 first degree relatives of 346 persons with primary open angle glaucoma, of 4972 individuals who were invited to participate attended the screening examination (Response Rate 7%). Fifty-five percent of those who attended were males and mean age of participants was 56.8 years. Sixty-eight relatives (13.3% of those screened) were detected to have definite glaucoma. Sixty percent of those detected with definite glaucoma were siblings. Fifteen percent of siblings, 4% of off-springs and 20% of parents who attended the screening examination had definite open angle glaucoma.
  
  
  CONCLUSIONS
  Prevalence of open angle glaucoma amongst first degree relatives of persons with glaucoma is higher than in the general population as reported in previous studies. Significant barriers, however, exist in the uptake of eye care services among relatives of persons known to have primary open angle glaucoma. How to cite this article: Rajendrababu S, Gupta N, Vijayakumar B, Kumaragurupari R, Krishnadas SR. Screening First Degree Relatives of Persons with Primary Open Angle Glaucoma in India. J Curr Glaucoma Pract 2014;8(3):107-112.
authors.affiliation: Senior Glaucoma Consultant, Department of Glaucoma, Aravind Eye Hospital, Madurai Tamil Nadu, India.
authors.forename: Sharmila
authors.initials: S
authors.lastname: Rajendrababu
authors.affiliation: Mediacal Officer, Aravind Eye Care System, Madurai, Tamil Nadu, India.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Gupta
authors.affiliation: Biostatistcian, Aravind Eye Care System, Madurai, Tamil Nadu, India.
authors.forename: B
authors.initials: B
authors.lastname: Vijayakumar
authors.affiliation: Librarian, Aravind Eye Care System, Madurai, Tamil Nadu, India.
authors.forename: R
authors.initials: R
authors.lastname: Kumaragurupari
authors.affiliation: Professor, Department of Glaucoma Services, Aravind Eye Care System Madurai, Tamil Nadu, India.
authors.forename: S R
authors.initials: SR
authors.lastname: Krishnadas
keywords: Family glaucoma; Family history; First degree relatives.; Heredity; Heredity history; Primary open angle glaucoma; Risk factor; Targeted factor; Targeted screening