title: Copper-catalyzed cross-coupling reactions of epoxides with gem-diborylmethane: access to γ-hydroxyl boronic esters.
abstract: Herein, we describe a novel copper-catalyzed epoxide opening reaction with gem-diborylmethane. Aliphatic, aromatic epoxides as well as aziridines are converted to the corresponding γ-pinacolboronate alcohols or amines in moderate to excellent yields. This new reaction provides beneficial applications for classic epoxide substrates as well as interesting gem-diborylalkane reagents.
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale, iChEM, CAS Key Laboratory of Urban Pollutant Conversion, Anhui Province Key Laboratory of Biomass Clean Energy, University of Science and Technology of China, Hefei 230026, China. binxiao@ustc.edu.cn fuyao@ustc.edu.cn.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Ebrahim-Alkhalil
authors.forename: Zhen-Qi
authors.initials: ZQ
authors.lastname: Zhang
authors.forename: Tian-Jun
authors.initials: TJ
authors.lastname: Gong
authors.forename: Wei
authors.initials: W
authors.lastname: Su
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Lu
authors.forename: Bin
authors.initials: B
authors.lastname: Xiao
authors.forename: Yao
authors.initials: Y
authors.lastname: Fu
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D003300:Copper / Q000737:chemistry*; D004852:Epoxy Compounds / Q000737:chemistry*; D004952:Esters; D008697:Methane / Q000737:chemistry*
chemical_list: D001896:Boron Compounds; D004852:Epoxy Compounds; D004952:Esters; D003300:Copper; D008697:Methane