title: Evaluation of nailfold videocapillaroscopy in central serous chorioretinopathy.
abstract: BACKGROUND
  Nailfold videocapillaroscopy (NVC) is a diagnostic tool to evaluate micro-vasculature. The presence of choroidal vasculopathy is apparent in central serous chorioretinopathy (CSCR).
  
  
  OBJECTIVE
  This study was aimed at assessing capillaroscopic nailfold findings in patients with CSCR. To the best of our knowledge, there is no study assessing NVC findings in CSCR in the literature.
  
  
  METHODS
  Sixty-one patients with CSCR who met the inclusion criteria, and 82 age- and sex-matched healthy controls were included to the study. A videocapillaroscopy device with 200× magnification was used for capillaroscopic assessment.
  
  
  RESULTS
  The mean age was 48.79 ± 11.15 years in the patient group (13 female, 48 male) and 49.38 ± 9.02 years in the control group (17 female, 65 male). The age and gender were comparable in the patient and control groups (p = 0.727 and p = 0.933, respectively). The capillary count was found to be decreased in the patient group compared to control group. No significant correlation was found between capillary count and choroidal thickness (p = 0.551; r = -0.081). In the patient group, the frequencies of major capillaroscopic findings including capillary ectasia, aneurysm, micro-hemorrhage, avascular area, tortuosity, neo-formation, bizarre capillary, bushy capillary, meander capillary and extravasation were found to be increased in the patient group. However, no significant correlation was detected between capillaroscopic findings and disease type and presence of attacks.
  
  
  CONCLUSIONS
  This is first study in which nailfold capillary assessment was performed in patients with CSCR, and we detected major capillaroscopic changes. These findings suggest that CSCR can be a systemic microvasculopathy. Further studies are needed to clarify the diagnostic and prognostic value of capillaroscopy in CSCR.
authors.affiliation: Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey. muhammetkazimerol@gmail.com.
authors.forename: Muhammet Kazim
authors.initials: MK
authors.lastname: Erol
authors.affiliation: Department of Internal Medicine, Division of Rheumatology, Antalya Education and Research Hospital, Antalya, Turkey.
authors.forename: Ayse
authors.initials: A
authors.lastname: Balkarli
authors.affiliation: Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey.
authors.forename: Devrim
authors.initials: D
authors.lastname: Toslak
authors.affiliation: Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey.
authors.forename: Berna
authors.initials: B
authors.lastname: Dogan
authors.affiliation: Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey.
authors.forename: Dogan
authors.initials: D
authors.lastname: Durmaz
authors.affiliation: Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey.
authors.forename: Elçin
authors.initials: E
authors.lastname: Süren
authors.affiliation: Department of Ophtholmology, Gulhane Military Medical Academy, Ankara, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Altun
authors.affiliation: Department of Ophtholmology, Antalya Education and Research Hospital, Kazim Karabekir Avenue, 07720, Muratpaşa, Antalya, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bulut
authors.affiliation: Department of Internal Medicine, Division of Rheumatology, Pamukkale University Hospital, Denizli, Turkey.
authors.forename: Veli
authors.initials: V
authors.lastname: Cobankara
mesh_terms: D000328:Adult; D002196:Capillaries / Q000473:pathology; D056833:Central Serous Chorioretinopathy / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D020678:Microscopic Angioscopy; D008875:Middle Aged; D009262:Nails / Q000098:blood supply*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology
keywords: Central serous chorioretinopathy; Choroidal vasculopathy; Nailfold videocapillaroscopy