title: The Use of Flow Diversion for the Treatment of Intracranial Aneurysms: Expansion of Indications.
abstract: Flow diversion is a novel concept for treating anatomically challenging intracranial aneurysms and has gained increasing acceptance. Flow diverter stents, such as the Pipeline Embolization Device (PED) (ev3-Covidien, Irvine, CA, USA), are approved for treating unruptured large and giant aneurysms from the internal carotid artery between the superior hypophyseal and cavernous segments. However, technological advances and recent clinical results suggest that flow diversion can be safely and effectively used in treating ruptured aneurysms, posterior circulation aneurysms, and distal anterior circulation aneurysms. In this brief review, we aim to investigate the recent evidence on the utilization of PEDs in these controversial vascular territories and to discuss whether the indications for flow diversion can be expanded.
authors.affiliation: Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
authors.forename: Adam M
authors.initials: AM
authors.lastname: Brouillard
authors.affiliation: Department of Neurosurgery, Weill Cornell Medical College ; New York Presbyterian Hospital.
authors.forename: Xingwen
authors.initials: X
authors.lastname: Sun
authors.affiliation: Department of Neurosurgery, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo, New York.
authors.forename: Adnan H
authors.initials: AH
authors.lastname: Siddiqui
authors.affiliation: Department of Neurosurgery, Weill Cornell Medical College.
authors.forename: Ning
authors.initials: N
authors.lastname: Lin
keywords: coil embolization; complication; endovascular treatment; flow diversion; intracranial aneurysm; ruptured aneurysm