title: Infection in Burns.
abstract: BACKGROUND
  Developments in critical care and surgical approaches to treating burn wounds, together with newer antimicrobial treatments, have significantly reduced the morbidity and mortality rates associated with this injury.
  
  
  METHODS
  Review of the pertinent English-language literature.
  
  
  RESULTS
  Several resistant organisms have emerged as the maleficent cause of invasive infection in burn patients, including methicillin-resistant Staphylococcus aureus, vancomycin-resistant Enterococcus, Pseudomonas, Acinetobacter, non-albicans Candida spp., and Aspergillus. Advances in antimicrobial therapies and the release of new classes of antibiotics have certainly added to the armamentarium of therapeutic resources for the clinician.
  
  
  CONCLUSIONS
  Strict infection control measures, constant wound surveillance with regular sampling of tissues for quantitative culture, and early excision and wound closure remain the principal adjuncts to control of invasive infections in burn patients.
authors.affiliation: 1 Shriners Hospitals for Children , Galveston, Texas.
authors.forename: William
authors.initials: W
authors.lastname: Norbury
authors.affiliation: 1 Shriners Hospitals for Children , Galveston, Texas.|2 Department of Surgery, University of Texas Medical Branch , Galveston, Texas.
authors.forename: David N
authors.initials: DN
authors.lastname: Herndon
authors.affiliation: 1 Shriners Hospitals for Children , Galveston, Texas.|2 Department of Surgery, University of Texas Medical Branch , Galveston, Texas.
authors.forename: Jessica
authors.initials: J
authors.lastname: Tanksley
authors.affiliation: 3 Ross Tilley Burn Centre, Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Department of Surgery, Division of Plastic Surgery and Department of Immunology, University of Toronto , Toronto, Ontario, Canada .
authors.forename: Marc G
authors.initials: MG
authors.lastname: Jeschke
authors.affiliation: 1 Shriners Hospitals for Children , Galveston, Texas.|2 Department of Surgery, University of Texas Medical Branch , Galveston, Texas.|4 Institute for Translational Science and Sealy Center for Molecular Medicine, University of Texas Medical Branch , Galveston, Texas.
authors.forename: Celeste C
authors.initials: CC
authors.lastname: Finnerty
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000628:therapy; D002056:Burns / Q000150:complications*; D003646:Debridement; D006801:Humans; D009181:Mycoses / Q000453:epidemiology* / Q000382:microbiology* / Q000628:therapy
chemical_list: D000890:Anti-Infective Agents