title: Comparison of effectiveness of 1,064-nm Nd:YAG laser and Nd:YAG laser-IPL combination treatments in hand skin rejuvenation.
abstract: OBJECTIVE
  Evaluation of the efficacy and side effects of neodymium-doped yttrium aluminum garnet (Nd:YAG) laser and Nd:YAG laser-intense pulsed light (IPL) combination treatments in photorejuvenations of skin of the hand, and determining their impacts on patient satisfaction.
  
  
  METHODS
  Thirty-five female patients with signs of photoaging on the skin of their hands were included in the study. Three sessions of IPL and four sessions of Nd:YAG laser treatment were applied to the right hand in total with 2-week intervals between each session, whereas six sessions of Nd:YAG laser treatment were applied to the left hand of patients with 2-week intervals between each session.
  
  
  RESULTS
  The patients' ages ranged between 31 and 78, and mean age was 60.77 ± 9.48. While there was no difference in pigment distribution, fine wrinkles, coarse wrinkles, and global scores between the right and left hand prior to treatment (p > 0.05), average pigment tone score was higher in the right hand with a statistically significant difference (p < 0.05). There was greater improvement in scores of pigment distribution, fine wrinkles, sallowness, pigment tone parameters, and global score on the right hand compared to left hand, which was statistically significant (p <0.001).
  
  
  CONCLUSIONS
  In rejuvenation of photoaged dorsal skin of the hand, IPL-Nd:YAG laser combination treatment surpasses Nd:YAG laser treatment.
authors.affiliation: a Dermatology, Numune Training and Research Hospital , Ankara , Turkey.
authors.forename: Ayse
authors.initials: A
authors.lastname: Oktem
authors.affiliation: b Department of Dermatology , Ankara University Faculty of Medicine , Ankara , Turkey.
authors.forename: Pelin
authors.initials: P
authors.lastname: Kocyigit
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006225:Hand; D006801:Humans; D062325:Intense Pulsed Light Therapy; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D008875:Middle Aged; D017060:Patient Satisfaction; D012060:Rejuvenation; D015595:Skin Aging / Q000528:radiation effects*; D016896:Treatment Outcome
keywords: 1,064-nm Nd-YAG laser; IPL; hand rejuvenation; non-ablative skin rejuvenation