title: Metformin - For the dermatologist.
abstract: Metformin though primarily an antidiabetic drug, has found to play an important role in a number of cutaneous disorders. Because of its role in improving hyperinsulinemia, it has proven beneficial in hormonal acne, hidradenitis suppurativa (HS) and acanthosis nigricans. Its antiandrogenic properties further serve as an add-on to the conventional management of hirsutism associated with polycystic ovarian syndrome. Very recently, systemic usage of metformin for psoriasis and cutaneous malignancies has shown promising results. Interestingly, metformin has also been topically used in hyperpigmentary disorders with pertinent levels of improvement and happens to be the most recent addition to the list of dermatologic indications. Though an oral hypoglycemic agent to begin with, metformin today has proven to be a boon for dermatologists.
authors.affiliation: Assistant Professor, Department of Dermatology, Sri Ramachandra University, Porur, Chennai, Tamil Nadu, India.
authors.forename: Aditya Kumar
authors.initials: AK
authors.lastname: Bubna
mesh_terms: D001682:Biological Availability; D005260:Female; D006801:Humans; D007004:Hypoglycemic Agents / Q000493:pharmacokinetics / Q000627:therapeutic use*; D008687:Metformin / Q000493:pharmacokinetics / Q000627:therapeutic use*; D011085:Polycystic Ovary Syndrome / Q000188:drug therapy*; D012871:Skin Diseases / Q000188:drug therapy*
chemical_list: D007004:Hypoglycemic Agents; D008687:Metformin
keywords: Hyperandrogenism; hyperinsulinemia; hyperpigmentary disorders; metformin; skin cancer