title: Use of XenX™, the latest ureteric occlusion device with guide wire utility: results from a prospective multicentric comparative study.
abstract: OBJECTIVE
  This is a prospective multicentric comparative study evaluating the performance of XenX-a new dual-purpose device for the prevention of stone fragments migration during ureteroscopic lithotripsy (URS).
  
  
  METHODS
  Between March 2014 and January 2015, 41 patients undertaking URS + XenX were matched with 41 patients undergoing standard URS. Patients included had unilateral ureteric stone(s) of 0.5-1.5 cm in maximum size. Demographics, complication rates and surgical outcomes were recorded for comparison. A Likert-like 5-grade scoring system was used for surgeons' evaluation of XenX properties. Cost analysis was performed by comparing weighted mean costs of the relevant procedures.
  
  
  RESULTS
  Patients' characteristics between the two groups were comparable. Lasering time was longer for XenX group (13.59 vs. 5.17 min; p = 0.0001) whilst use of basket and need of JJ stent insertion was more frequent in control group (19.5 vs. 97.6 %; p = 0.0001 and 22 vs. 35 %; p = 0.001, respectively). Intra-operative SFR was significantly higher for XenX group (100 vs. 85.4 %; p = 0.0001), but not at 4-week follow-up, after ancillary procedures were needed in 17.1 % of the control group. Surgeons' evaluations for XenX were suboptimal for "Ease of Basketing" (2/5) and "Advancement of double J stent" (3/5). The use of XenX increased costs of procedures, but spared the costs associated to ancillary procedures and stent removals.
  
  
  CONCLUSIONS
  XenX confirmed to be a safe and effective device especially for the treatment of upper ureteric tract stones; moreover, XenX may reduce the risk for the need of auxiliary procedures and for the insertion of a JJ stent.
authors.affiliation: King's College Hospital, NHS Foundation Trust, London, UK. fsangue@hotmail.com.|Northampton General Hospital, Northampton, UK. fsangue@hotmail.com.
authors.forename: Francesco
authors.initials: F
authors.lastname: Sanguedolce
authors.affiliation: San Paolo Hospital, University of Milano, Milan, Italy.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Montanari
authors.affiliation: Infanta Sofia University Hospital, Madrid, Spain.
authors.forename: Mario
authors.initials: M
authors.lastname: Alvarez-Maestro
authors.affiliation: San Paolo Hospital, University of Milano, Milan, Italy.
authors.forename: Nicola
authors.initials: N
authors.lastname: Macchione
authors.affiliation: Paracelsus Medical University Salzburg, Salzburg, Austria.
authors.forename: Stephan
authors.initials: S
authors.lastname: Hruby
authors.affiliation: Sismanoglio General Hospital, Athens, Greece.
authors.forename: Athanasios
authors.initials: A
authors.lastname: Papatsoris
authors.affiliation: Patras University Hospital, Patras, Greece.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Kallidonis
authors.affiliation: Tenon University Hospital, Paris, France.
authors.forename: Luca
authors.initials: L
authors.lastname: Villa
authors.affiliation: Sindelfingen-Böblingen Clinic, Boblingen, Germany.
authors.forename: Patrick
authors.initials: P
authors.lastname: Honeck
authors.affiliation: Patras University Hospital, Patras, Greece.
authors.forename: Olivier
authors.initials: O
authors.lastname: Traxer
authors.affiliation: Romolo Hospital, Rocca di Neto, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Greco
mesh_terms: D004867:Equipment Design; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008096:Lithotripsy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D015607:Stents; D016896:Treatment Outcome; D014513:Ureter / Q000000981:diagnostic imaging; D014514:Ureteral Calculi / Q000175:diagnosis / Q000628:therapy*; D018666:Ureteroscopy / Q000295:instrumentation*
keywords: Endoscopic lithotripsy; New technology; Preventive retropulsion device; Ureteric stone