title: Ion-Doped Silicate Bioceramic Coating of Ti-Based Implant.
abstract: Titanium and its alloy are known as important load-bearing biomaterials. The major drawbacks of these metals are fibrous formation and low corrosion rate after implantation. The surface modification of biomedical implants through various methods such as plasma spray improves their osseointegration and clinical lifetime. Different materials have been already used as coatings on biomedical implant, including calcium phosphates and bioglass. However, these materials have been reported to have limited clinical success. The excellent bioactivity of calcium silicate (Ca-Si) has been also regarded as coating material. However, their high degradation rate and low mechanical strength limit their further coating application. Trace element modification of (Ca-Si) bioceramics is a promising method, which improves their mechanical strength and chemical stability. In this review, the potential of trace element-modified silicate coatings on better bone formation of titanium implant is investigated.
authors.affiliation: School of Materials and Mineral Resources Engineering, Universiti Sains Malaysia, Engineering Campus, 14300 Nibong Tebal, Penang, Malaysia.
authors.forename: Hossein
authors.initials: H
authors.lastname: Mohammadi
authors.affiliation: Department of Stem Cell and Developmental Biology, Cell Science Research Center, Royan Institute for Stem Cell Biology and Technology, ACECR, Tehran, Iran.|Department of Metallurgy and Materials Engineering, Faculty of Engineering, University of Semnan, Semnan, Iran.
authors.forename: Mohammadmajid
authors.initials: M
authors.lastname: Sepantafar
mesh_terms: D019643:Arthroplasty, Replacement / Q000295:instrumentation* / Q000379:methods; D001672:Biocompatible Materials / Q000737:chemistry / Q000494:pharmacology*; D017610:Calcium Compounds / Q000737:chemistry / Q000494:pharmacology; D002130:Calcium Phosphates / Q000737:chemistry / Q000494:pharmacology; D002516:Ceramics / Q000737:chemistry / Q000494:pharmacology*; D016348:Osseointegration / Q000502:physiology*; D010012:Osteogenesis / Q000502:physiology*; D019736:Prostheses and Implants; D017640:Silicates / Q000737:chemistry / Q000494:pharmacology; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry / Q000494:pharmacology*; D014131:Trace Elements / Q000737:chemistry / Q000494:pharmacology
chemical_list: D001672:Biocompatible Materials; C022107:Bioglass; D017610:Calcium Compounds; D002130:Calcium Phosphates; D017640:Silicates; D014131:Trace Elements; D014025:Titanium; C031293:calcium silicate
keywords: Coating; Modified silicate ceramics; Plasma spray; Ti implant