title: A rapid-response fluorescent probe for the sensitive and selective detection of human albumin in plasma and cell culture supernatants.
abstract: A rapid-response fluorescent probe ACDM was developed for the selective and sensitive detection of human albumin (HA) via binding onto a non-drug binding site. ACDM was successfully used to detect trace HA in various biological samples including diluted plasma and cell culture supernatants.
authors.affiliation: Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China. geguangbo@dicp.ac.cn lingdicp@gmail.com.
authors.forename: Yi-Ru
authors.initials: YR
authors.lastname: Wang
authors.forename: Lei
authors.initials: L
authors.lastname: Feng
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.forename: Dan-Dan
authors.initials: DD
authors.lastname: Wang
authors.forename: Jie
authors.initials: J
authors.lastname: Hou
authors.forename: Kun
authors.initials: K
authors.lastname: Zhou
authors.forename: Qiang
authors.initials: Q
authors.lastname: Jin
authors.forename: Guang-Bo
authors.initials: GB
authors.lastname: Ge
authors.forename: Jing-Nan
authors.initials: JN
authors.lastname: Cui
authors.forename: Ling
authors.initials: L
authors.lastname: Yang
mesh_terms: D001665:Binding Sites; D002623:Chemistry Techniques, Analytical / Q000379:methods*; D002851:Chromatography, High Pressure Liquid; D005456:Fluorescent Dyes / Q000737:chemistry*; D005663:Furans / Q000737:chemistry; D056945:Hep G2 Cells; D006801:Humans; D056004:Molecular Dynamics Simulation; D017434:Protein Structure, Tertiary; D012709:Serum Albumin / Q000032:analysis* / Q000737:chemistry; D053719:Tandem Mass Spectrometry
chemical_list: D005456:Fluorescent Dyes; D005663:Furans; D012709:Serum Albumin; C039281:furan