title: [Antibody-based agents as experimental therapeutic interventions for corneal allograft rejection].
abstract: The corneal allograft rejection is the primary reason for graft failure, but the existing agents are of limited efficacy and may be accompanied by unacceptable morbidity. Recently, antibody-based agents have received great attention and have become an important part of therapeutic intervention for organ transplantation, which is also a research focus in the field of corneal transplantation. This review summarizes the history, current situation and mechanism of antibody-based agents in corneal transplantation.
authors.affiliation: Department of Ophthalmology, The Affiliated Hospital of Chengde Medical College, Chengde 067000, China.
authors.forename: X B
authors.initials: XB
authors.lastname: Tan
authors.forename: T M
authors.initials: TM
authors.lastname: Zhang
authors.forename: Z Q
authors.initials: ZQ
authors.lastname: Pan
mesh_terms: D064591:Allografts; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003316:Corneal Diseases / Q000188:drug therapy*; D016039:Corneal Transplantation; D006084:Graft Rejection / Q000188:drug therapy*; D006801:Humans; D014184:Transplantation, Homologous
chemical_list: D000911:Antibodies, Monoclonal