title: Probing the self-assembly and stability of oligohistidine based rod-like micelles by aggregation induced luminescence.
abstract: The synthesis and self-assembly of a new C2-symmetric oligohistidine amphiphile equipped with an aggregation induced emission luminophore is reported. We observe the formation of highly stable and ordered rod-like micelles in phosphate buffered saline, with a critical aggregation concentration below 200 nM. Aggregation induced emission of the luminophore confirms the high stability of the anisotropic assemblies in serum.
authors.affiliation: Institute of Organic Chemistry, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany. besenius@uni-mainz.de.
authors.forename: Hendrik
authors.initials: H
authors.lastname: Frisch
authors.affiliation: Institute of Organic Chemistry, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany. besenius@uni-mainz.de.
authors.forename: Daniel
authors.initials: D
authors.lastname: Spitzer
authors.affiliation: Institute of Physical Chemistry, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany.
authors.forename: Mathias
authors.initials: M
authors.lastname: Haase
authors.affiliation: Institute of Physical Chemistry, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Basché
authors.affiliation: Institute of Organic Chemistry, University of Duisburg-Essen, Universitätsstrasse 7, D-45117 Essen, Germany. jens.voskuhl@uni-due.de.
authors.forename: Jens
authors.initials: J
authors.lastname: Voskuhl
authors.affiliation: Institute of Organic Chemistry, Johannes Gutenberg-Universität Mainz, Duesbergweg 10-14, D-55128 Mainz, Germany. besenius@uni-mainz.de.
authors.forename: Pol
authors.initials: P
authors.lastname: Besenius
mesh_terms: D006639:Histidine / Q000031:analogs & derivatives / Q000138:chemical synthesis / Q000737:chemistry*; D049449:Luminescence; D008823:Micelles; D010316:Particle Size
chemical_list: D008823:Micelles; D006639:Histidine