title: Anti-Psoriasis Agents from Natural Plant Sources.
abstract: Psoriasis is a chronic inflammatory immune-mediated skin disease. It affects most races, does not have any sexual predilections and can manifest at any age of life. Psoriasis is more frequent in certain racial groups and geographical areas. For these reasons, both genetic and environmental factors could be considered. In this review, we discuss promising natural compounds, their molecular targets and mechanisms, which may help the further design of new anti-psoriasis agents. Literature documents the widespread use of herbal remedies worldwide, and the presence of some phytochemicals supports the efficacy of some botanical treatments. The research on natural products has greatly contributed to the progress in the treatment of skin diseases such as psoriasis and many of these compounds are now being used. Understanding the mechanism of these molecules will contribute to the development of more specific preventive strategies for the treatment of psoriasis.
authors.forename: Marco
authors.initials: M
authors.lastname: Bonesi
authors.forename: Monica Rosa
authors.initials: MR
authors.lastname: Loizzo
authors.forename: Eugenio
authors.initials: E
authors.lastname: Provenzano
authors.forename: Francesco
authors.initials: F
authors.lastname: Menichini
authors.affiliation: Department of Pharmacy, Health and Nutritional Sciences, University of Calabria, 87036 Rende (CS), Italy. rosa.tundis@unical.it.
authors.forename: Rosa
authors.initials: R
authors.lastname: Tundis
mesh_terms: D001688:Biological Products / Q000627:therapeutic use*; D006801:Humans; D011565:Psoriasis / Q000188:drug therapy*
chemical_list: D001688:Biological Products