title: [Bleeding and thrombosis – acute complications of liver cirrhosis].
abstract: Patients with acute and chronic liver disease have a rebalanced hemostasis, i.e. these patients have an increased tendency for both bleeding and thrombosis.Bleeding is primarily related to portal hypertension, rather than a defective hemostasis. There are well-established clinical guidelines for the management of patients with liver cirrhosis and variceal bleeding.Epidemiological studies have demonstrated an increased risk of venous thromboembolism in patients with liver cirrhosis. The treatment of patients with liver cirrhosis and venous thrombosis is not well documented. Treatment with anticoagulants should be considered in patients with symptomatic, extensive or progressive thrombosis of the portal system, as well as in patients who are being considered for liver transplantation.
authors.affiliation: Gastrocentrum - Sektionen för Hepatologi Stockholm, Sweden Gastrocentrum - Sektionen för Hepatologi Stockholm, Sweden.
authors.forename: Rupesh
authors.initials: R
authors.lastname: Rajani
authors.affiliation: Sahlgrenska Universitetssjukhuset - Göteborg, Sweden Sahlgrenska Universitetssjukhuset - Göteborg, Sweden.
authors.forename: Hanns-Ulrich
authors.initials: HU
authors.lastname: Marschall
mesh_terms: D000208:Acute Disease; D000465:Algorithms; D004932:Esophageal and Gastric Varices / Q000150:complications / Q000188:drug therapy / Q000601:surgery; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006487:Hemostasis / Q000502:physiology; D006801:Humans; D006975:Hypertension, Portal / Q000150:complications; D008103:Liver Cirrhosis / Q000150:complications* / Q000503:physiopathology; D011169:Portal Vein; D011655:Pulmonary Embolism / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D013927:Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D020246:Venous Thrombosis / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery