title: Nursing Care of Patients Undergoing Chemotherapy Desensitization: Part II.
abstract: Chemotherapy desensitization protocols are safe, but labor-intensive, processes that allow patients with cancer to receive medications even if they initially experienced severe hypersensitivity reactions. Part I of this column discussed the pathophysiology of hypersensitivity reactions and described the development of desensitization protocols in oncology settings. Part II incorporates the experiences of an academic medical center and provides a practical guide for the nursing care of patients undergoing chemotherapy desensitization. .
authors.affiliation: UCLA Medical Center, Santa Monica, CA.
authors.forename: Patricia
authors.initials: P
authors.lastname: Jakel
authors.affiliation: Santa Monica Medical Center.
authors.forename: Cynthia
authors.initials: C
authors.lastname: Carsten
authors.affiliation: Santa Monica Medical Center.
authors.forename: Arvie
authors.initials: A
authors.lastname: Carino
authors.affiliation: David Geffen School of Medicine.
authors.forename: Melinda
authors.initials: M
authors.lastname: Braskett
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage / Q000009:adverse effects*; D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000188:drug therapy* / Q000451:nursing; D003888:Desensitization, Immunologic / Q000379:methods* / Q000451:nursing; D004342:Drug Hypersensitivity / Q000276:immunology / Q000451:nursing*; D005260:Female; D006801:Humans; D008875:Middle Aged; D024802:Nurse's Role; D009859:Oncology Nursing / Q000379:methods; D061214:Patient Safety; D018570:Risk Assessment; D016896:Treatment Outcome
keywords: adverse drug reactions; chemotherapy desensitization; hypersensitivity reactions; infusion reactions; rapid drug desensitization