title: Association between the Red Cell Distribution Width and Vasospastic Angina in Korean Patients.
abstract: OBJECTIVE
  The association between the red cell distribution width (RDW) and vasospastic angina (VSA) has not been elucidated. We investigated the association of the RDW with the incidence and angiographic subtypes of VSA in Korean patients.
  
  
  METHODS
  A total of 460 patients who underwent intracoronary ergonovine provocation tests were consecutively enrolled and classified into two groups: the VSA group (n=147, 32.0%) and non-VSA group (n=313, 68.0%). The subjects were classified into 3 subgroups (tertiles) according to the baseline level of RDW assessed before the angiographic provocation test.
  
  
  RESULTS
  The VSA group had a higher RDW than the non-VSA group (12.9±0.8% vs. 12.5±0.7%, p=0.013). The high RDW level demonstrated an independent association with the high incidence of VSA [second tertile: hazard ratio (HR) 1.96 (1.13-2.83), third tertile: HR 2.33 (1.22-3.47), all p<0.001]. Moreover, the highest RDW tertile level had a significant association with the prevalence of the mixed-type coronary spasm [HR 1.29 (1.03-1.59), p=0.037].
  
  
  CONCLUSIONS
  The high level of RDW was significantly associated with the prevalence of VSA and the high-risk angiographic subtype of coronary spasm, suggesting that a proactive clinical investigation for VSA could be valuable in Korean patients with an elevated RDW.
authors.affiliation: Department of Cardiovascular Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
authors.forename: Mi-Hyang
authors.initials: MH
authors.lastname: Jung
authors.affiliation: Department of Cardiovascular Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea. auguscardio@gmail.com.
authors.forename: Dong Il
authors.initials: DI
authors.lastname: Shin
authors.affiliation: Department of Cardiovascular Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
authors.forename: Ik Jun
authors.initials: IJ
authors.lastname: Choi
authors.affiliation: Department of Cardiovascular Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Korea.
authors.forename: Suk Min
authors.initials: SM
authors.lastname: Seo
authors.affiliation: Department of Cardiovascular Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea.
authors.forename: Sooa
authors.initials: S
authors.lastname: Choi
authors.affiliation: Department of Cardiovascular Medicine, Daejeon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Daejeon, Korea.
authors.forename: Mahn Won
authors.initials: MW
authors.lastname: Park
authors.affiliation: Department of Cardiovascular Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Pum-Joon
authors.initials: PJ
authors.lastname: Kim
authors.affiliation: Department of Cardiovascular Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Sang Hong
authors.initials: SH
authors.lastname: Baek
authors.affiliation: Department of Cardiovascular Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea.
authors.forename: Ki-Bae
authors.initials: KB
authors.lastname: Seung
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000787:Angina Pectoris / Q000097:blood* / Q000208:ethnology; D017023:Coronary Angiography / Q000379:methods; D003329:Coronary Vasospasm / Q000097:blood* / Q000208:ethnology; D004909:Erythrocyte Indices / Q000502:physiology*; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016016:Proportional Hazards Models; D056910:Republic of Korea / Q000453:epidemiology
keywords: Angina pectoris; coronary vasospasm; erythrocyte indices; variant