title: [Outcome of triplet pregnancies managed for twin-to-twin transfusion syndrome: A single center experience].
abstract: OBJECTIVE
  Study the outcomes of triplet pregnancies (GGG) complicated with twin-to-twin transfusion syndrome (TTTS) treated with laser fetoscopy.
  
  
  METHODS
  Retrospective study of interventions, outcomes and perinatal follow-up of GGG treated for TTS.
  
  
  RESULTS
  Between 2002 and 2013, 25 GGG complicated by TTTS were seen in our center, 20 dichorionic and 5 monochorionic. The mean gestational age (GA) at diagnosis of TTTS was 19.7 GW (±2.4) with 2, 4, 16 and 1 pregnancies at Quintero's stage I, II, III and V, respectively. They had a fetoscopy at an average GA of 19 GW and 6 days. There were 3 (13.0%) late miscarriages. The average GA at delivery was of 29.6 GW overall (26.3 GW and 31.1 GW in monochorionic and dichorionic pregnancies respectively). The overall fetal survival rate was 57.97% (40% and 66.7% in the group of monochorionic dichorionic pregnancies, respectively). However, neonatal mortality (<28 days) is 17.5%.
  
  
  CONCLUSIONS
  GGG operated by fetoscopy for TTTS have a survival rate of three, at least 2 and at least 1 fetus of 21.7%, 69.6% and 82.6% respectively. The overall fetal survival rate is 59.97%. There is a tendency for better survival rates in dichorionic GGG compared to monochorionic GGG (P=0.079).
authors.affiliation: Centre maladies rares, syndrome transfuseur-transfusé, hôpital Necker-Enfants-Malades, AP-HP, 75015 Paris, France; Maternité et service de médecine fœtale, hôpital Necker-Enfants-Malades, université Paris Descartes, Sorbonne Paris Cité, AP-HP, 149, rue de Sèvres, Paris, France.
authors.forename: G E
authors.initials: GE
authors.lastname: Chalouhi
authors.affiliation: Service de gynécologie obstétrique, centre hospitalier intercommunal Poissy-Saint-Germain-en-Laye, 78300 Poissy, France.
authors.forename: T
authors.initials: T
authors.lastname: Quibel
authors.affiliation: Centre maladies rares, syndrome transfuseur-transfusé, hôpital Necker-Enfants-Malades, AP-HP, 75015 Paris, France; Maternité et service de médecine fœtale, hôpital Necker-Enfants-Malades, université Paris Descartes, Sorbonne Paris Cité, AP-HP, 149, rue de Sèvres, Paris, France.
authors.forename: N
authors.initials: N
authors.lastname: Benzina
authors.affiliation: Centre maladies rares, syndrome transfuseur-transfusé, hôpital Necker-Enfants-Malades, AP-HP, 75015 Paris, France; Maternité et service de médecine fœtale, hôpital Necker-Enfants-Malades, université Paris Descartes, Sorbonne Paris Cité, AP-HP, 149, rue de Sèvres, Paris, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Bernard
authors.affiliation: Centre maladies rares, syndrome transfuseur-transfusé, hôpital Necker-Enfants-Malades, AP-HP, 75015 Paris, France; Maternité et service de médecine fœtale, hôpital Necker-Enfants-Malades, université Paris Descartes, Sorbonne Paris Cité, AP-HP, 149, rue de Sèvres, Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Essaoui
authors.affiliation: Centre maladies rares, syndrome transfuseur-transfusé, hôpital Necker-Enfants-Malades, AP-HP, 75015 Paris, France; Maternité et service de médecine fœtale, hôpital Necker-Enfants-Malades, université Paris Descartes, Sorbonne Paris Cité, AP-HP, 149, rue de Sèvres, Paris, France. Electronic address: ville.yves@gmail.com.
authors.forename: Y
authors.initials: Y
authors.lastname: Ville
mesh_terms: D000328:Adult; D005260:Female; D005315:Fetal Diseases / Q000401:mortality / Q000628:therapy*; D005330:Fetofetal Transfusion / Q000401:mortality / Q000628:therapy*; D005332:Fetoscopy / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D017063:Outcome Assessment, Health Care; D010920:Placenta / Q000098:blood supply*; D011247:Pregnancy; D011256:Pregnancy Outcome; D059286:Pregnancy, Triplet; D012189:Retrospective Studies; D055815:Young Adult
keywords: Dichorionic triplets; Fetoscopy; Fœtoscopie; Grossesse triple bichoriale; Grossesse triple monochoriale; Laser; Laser treatment; Monochorionic triplets; Survie; Survival; Syndrome transfuseur-transfusé; TTTS