title: Anaphylactic reactions in adult patients in Southern Israel.
abstract: BACKGROUND
  Southern Israel is inhabited by Jews and Bedouins. Children from these populations differ in the epidemiology of anaphylactic reactions; however, the effects of ethnicity on the epidemiology of anaphylactic reactions in adults in these populations are unknown.
  
  
  METHODS
  Retrospective review of medical records of patients with anaphylactic reactions treated in a single institution during 2008-2012.
  
  
  RESULTS
  A total of 192 evaluable cases of anaphylaxis were recorded; 155 (80.7%) anaphylactic reactions occurred in Jews and 37/192 (19.3%) occurred in Bedouins. A trend towards an older mean age of occurrence of anaphylaxis was recorded in Jewish patients compared with Bedouin patients: 48.1 years versus 41.2, respectively (P = 0.053). Anaphylaxis was more common in Jewish female patients than males and more common in Bedouin male patients than females. Overall, 93/155 (60.0%) females in Jewish patients were affected compared with 14/37 (37.8%) in the Bedouin population (P = 0.015). More Jewish patients had more anaphylaxis attributed to food compared with Bedouin patients: 31/155 (20%) versus 2/37 (5.4%) (P = 0.034). The mean yearly incidence of anaphylaxis was similar in Bedouin and Jewish patients: 12.1 ± 5.3 versus 17.6 ± 15.3, respectively (P = 0.466). However, a significant trend towards a higher incidence of anaphylactic reactions was recorded throughout the study years only in Jewish patients (r = 0.906, P = 0.034).
  
  
  CONCLUSIONS
  Adult Jewish patients have a significantly higher probability of having anaphylactic reactions due to food compared with Bedouin patients, with females being more affected, and the incidence of anaphylactic reaction is increasing only in the Jewish population. The epidemiology of anaphylactic reactions can differ between populations residing in the same geographical area.
authors.affiliation: Pediatric Allergy Clinic, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
authors.forename: Inna
authors.initials: I
authors.lastname: Hananashvili
authors.forename: Noga
authors.initials: N
authors.lastname: Givon-Lavi
authors.forename: Carmi
authors.initials: C
authors.lastname: Bartal
authors.forename: Arnon
authors.initials: A
authors.lastname: Broides
mesh_terms: D000328:Adult; D000707:Anaphylaxis / Q000453:epidemiology* / Q000208:ethnology; D018912:Arabs; D005260:Female; D006801:Humans; D015994:Incidence; D007557:Israel / Q000453:epidemiology; D007585:Jews; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies