title: RECIST Applied to Realistic Tumor Models.
abstract: RECIST (Response Evaluation Criteria in Solid Tumors) is a linear measure intended to predict tumor size in medical computed tomography (CT). In this work, using purely geometrical considerations, we estimate how well RECIST can predict the volume of randomly-oriented tumor models, each composed of the union of ellipsoids. The principal conclusion is that RECIST is likely to work less well for realistic tumors than for ellipsoids.
authors.affiliation: Optical Technology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899-8441.
authors.forename: Zachary H
authors.initials: ZH
authors.lastname: Levine
authors.affiliation: Optical Technology Division, National Institute of Standards and Technology, Gaithersburg, MD 20899-8441.
authors.forename: Benjamin R
authors.initials: BR
authors.lastname: Galloway
authors.affiliation: Applied and Computational Mathematics Division, National Institute of Standards and Technology, Boulder, CO 80305-3328.
authors.forename: Adele P
authors.initials: AP
authors.lastname: Peskin
keywords: RECIST; tumor size; volumetric measurement; x-ray imaging