title: Mutualistic viruses and the heteronomy of life.
abstract: Though viruses have generally been characterized by their pathogenic and more generally harmful effects, many examples of mutualistic viruses exist. Here I explain how the idea of mutualistic viruses has been defended in recent virology, and I explore four important conceptual and practical consequences of this idea. I ask to what extent this research modifies the way scientists might search for new viruses, our notion of how the host immune system interacts with microbes, the development of new therapeutic approaches, and, finally, the role played by the criterion of autonomy in our understanding of living things. Overall, I suggest that the recognition of mutualistic viruses plays a major role in a wider ongoing revision of our conception of viruses.
authors.affiliation: ImmunoConcept, UMR5164, CNRS, University of Bordeaux, France. Electronic address: thomas.pradeu@u-bordeaux.fr.
authors.forename: Thomas
authors.initials: T
authors.lastname: Pradeu
mesh_terms: D013559:Symbiosis; D018406:Virus Physiological Phenomena
keywords: Autonomy; Immune system; Microbiota; Mutualism; Symbiosis; Virus