title: A microporous silk carbon-ionic liquid composite for the electrochemical sensing of dopamine.
abstract: Porous silk carbon (Silk C) was obtained through carbonization and KOH activation of natural silk cocoons. The as-prepared Silk C presented the good characteristics of a large surface area (SBET: 2854.53 m(2) g(-1)) and a high volume of pores (1.54 cm(3) g(-1)) with uniform micropores (2.5 nm) and multiple defects. The metal-free silk carbon-ionic liquid (Silk C-IL) composite, synthesized by modifying Silk C with ionic liquid through non-covalent (π-π) interactions under grinding conditions, was prepared for electrochemical determination of dopamine (DA). The detection limit of DA was 79 nM (S/N = 3) with a linear range from 0.6 μM to 140 μM. Meanwhile, the as-made Silk C-IL/GCE presented good selectivity for DA detection from other possible interferences, such as ascorbic acid, glucose and uric acid. Furthermore, the Silk C-IL/GCE was also successfully used for the detection of DA in fetal bovine serum and dopamine hydrochloride injection samples.
authors.affiliation: State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun 130022, Jilin, P.R. China. dongsj@ciac.ac.cn.
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Lu
authors.initials: L
authors.lastname: Bai
authors.forename: Lingling
authors.initials: L
authors.lastname: Zhang
authors.forename: Guangping
authors.initials: G
authors.lastname: Sun
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Zhang
authors.forename: Shaojun
authors.initials: S
authors.lastname: Dong
mesh_terms: D004298:Dopamine / Q000032:analysis* / Q000737:chemistry; D004553:Electric Conductivity; D004563:Electrochemistry / Q000379:methods*; D004566:Electrodes; D006878:Hydroxides / Q000737:chemistry; D052578:Ionic Liquids / Q000737:chemistry*; D057230:Limit of Detection; D016062:Porosity; D017680:Potassium Compounds / Q000737:chemistry; D047011:Silk / Q000737:chemistry*
chemical_list: D006878:Hydroxides; D052578:Ionic Liquids; D017680:Potassium Compounds; D047011:Silk; D004298:Dopamine; C029943:potassium hydroxide