title: The interictal dysphoric disorder of epilepsy: Legend or reality?
abstract: For a long time, the relationships between epilepsy and mood disorders captured the attention of clinicians and neuroscientists. The existence of a peculiar clinical presentation for mood disorders in epilepsy has been a matter of debate since the early reports of Kraepelin and Bleuler. The interictal dysphoric disorder (IDD) represents the modern reinterpretation of such early observations. This paper reviews current research on this topic discussing clinical implications, phenomenological observations, and directions for future research.
authors.affiliation: Atkinson Morley Regional Neuroscience Centre, St. George's University Hospitals NHS Foundation Trust, Blackshaw Road, London SW17 0QT, United Kingdom; South West London & St. George's Mental Health Trust, London, United Kingdom; Institute of Medical and Biomedical Sciences, St. George's University of London, United Kingdom. Electronic address: mmula@sgul.ac.uk.
authors.forename: Marco
authors.initials: M
authors.lastname: Mula
mesh_terms: D004827:Epilepsy / Q000150:complications* / Q000523:psychology; D006801:Humans; D019964:Mood Disorders / Q000150:complications* / Q000523:psychology
keywords: Antiepileptic drugs; Bipolar disorder; Depression; Epilepsy; Interictal dysphoric disorder; Periictal dysphoric syndrome