title: Adult human metapneumonovirus (hMPV) pneumonia mimicking Legionnaire's disease.
abstract: In adults hospitalized with viral pneumonias the main differential diagnostic consideration is influenza pneumonia. The respiratory viruses causing viral influenza like illnesses (ILIs), e.g., RSV may closely resemble influenza. Rarely, extrapulmonary findings of some ILIs may resemble Legionnaire's disease (LD), e.g., adenovirus, human parainfluenza virus (HPIV-3). We present a most unusual case of human metapneumonovirus pneumonia (hMPV) with some characteristic extrapulmonary findings characteristic of LD, e.g., relative bradycardia, as well as mildly elevated serum transaminases and hyphosphatemia. We believe this is the first reported case of hMPV pneumonia in a hospitalized adult that had some features of LD.
authors.affiliation: Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA; State University of New York, School of Medicine, Stony Brook, NY, USA. Electronic address: bacunha@winthrop.org.
authors.forename: Burke A
authors.initials: BA
authors.lastname: Cunha
authors.affiliation: Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA; State University of New York, School of Medicine, Stony Brook, NY, USA.
authors.forename: Nadia
authors.initials: N
authors.lastname: Irshad
authors.affiliation: Infectious Disease Division, Winthrop-University Hospital, Mineola, NY, USA; State University of New York, School of Medicine, Stony Brook, NY, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Connolly
mesh_terms: D000328:Adult; D000914:Antibodies, Viral / Q000032:analysis*; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007877:Legionnaires' Disease / Q000175:diagnosis*; D008297:Male; D029121:Metapneumovirus / Q000276:immunology*; D018184:Paramyxoviridae Infections / Q000175:diagnosis* / Q000821:virology; D011024:Pneumonia, Viral / Q000175:diagnosis* / Q000821:virology
chemical_list: D000914:Antibodies, Viral
keywords: Elevated serum transaminases; Hyponatremia; Hypophosphatemia; Legionnaire's disease mimics; Relative bradycardia; Viral pneumonias