title: TO TREAT OR NOT TO TREAT, CHEYNE-STOKES RESPIRATION IN A YOUNG ADULT WITH VASCULAR ENCEPHALOPATHY.
abstract: Cheyne-Stokes respiration (CSR) is a form of sleep-disordered breathing characterised by recurrent central sleep apnoea alternating with a crescendo-decrescendo pattern of tidal volume, relatively rare observation in sleep labs. It is mainly seen in severe heart failure and stroke. We report the case of a young man with CSR after sudden onset of seizure in the context of hypertensive exacerbation leading to the diagnosis of a leukoencephalopathy, and comment on differential diagnoses, prognostic and therapeutic outcomes. The very uniqueness of this case consists in the extremely young age for developing a vascular encephalopathy in the absence of genetic diseases and without previous diagnosis of hypertension. There is no adequate explanation for the origin of vascular encephalopathy; also there is lack of evidence regarding the benefits and modality of treatment for CSR in neurologic diseases. Thus, we were forced to find the best compromise in a nocturnal oxygen therapy and follow-up.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Hubatsch
authors.forename: Harald
authors.initials: H
authors.lastname: Englert
authors.forename: Ulrich
authors.initials: U
authors.lastname: Wagner
mesh_terms: D000328:Adult; D001921:Brain / Q000098:blood supply* / Q000000981:diagnostic imaging / Q000473:pathology / Q000503:physiopathology; D002560:Cerebrovascular Circulation; D002639:Cheyne-Stokes Respiration / Q000209:etiology* / Q000628:therapy*; D003937:Diagnosis, Differential; D006801:Humans; D056784:Leukoencephalopathies / Q000150:complications* / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010100:Oxygen / Q000008:administration & dosage*; D010102:Oxygen Inhalation Therapy; D017286:Polysomnography; D011379:Prognosis; D012720:Severity of Illness Index; D012890:Sleep; D014057:Tomography, X-Ray Computed; D066127:White Matter / Q000473:pathology
chemical_list: D010100:Oxygen