title: Pattern Electroretinography Changes in Patients with Established or Suspected Primary Open Angle Glaucoma.
abstract: OBJECTIVE
  To assess pattern electroretinogram (PERG) changes in patients with established or suspected primary open angle glaucoma (POAG).
  
  
  METHODS
  Transient PERG using LV Prasad eye electrodes were performed in 76 normal, 32 glaucomatous and 22 glaucoma suspect eyes. The P50 amplitude, N95 amplitude and P50 latency were analyzed. The results were further analyzed with receiver operating characteristic (ROC) curves and discriminant function analysis (DFA).
  
  
  RESULTS
  The P50 and N95 amplitude of the POAG and glaucoma suspect groups were significantly reduced. There was significant shortening in the P50 latency in the POAG and glaucoma suspect groups. DFA using the P50 amplitude, N95 amplitude and P50 latency waveform parameters showed a sensitivity and specificity of 76.67 and 88.57% respectively.
  
  
  CONCLUSIONS
  Pattern ERG demonstrated significant changes in POAG patients and suspects. ROC curves for the three wave parameters demonstrated that N95 amplitude was the better indicator for diagnosis of POAG when used individually. How to cite this article: Ganekal S, Dorairaj S, Jhanji V. Pattern Electroretinography Changes in Patients with Established or Suspected Primary Open Angle Glaucoma. J Current Glau Prac 2013;7(2):39-42.
authors.affiliation: Nayana Super Speciality Eye Hospital and Research Center Davangere, Karnataka, India.
authors.forename: Sunil
authors.initials: S
authors.lastname: Ganekal
authors.affiliation: Department of Ophthalmology, Mayo Clinic Jacksonville, Florida USA.
authors.forename: Syril
authors.initials: S
authors.lastname: Dorairaj
authors.affiliation: Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong.
authors.forename: Vishal
authors.initials: V
authors.lastname: Jhanji
keywords: Glaucoma suspects.; Pattern ERG; Primary open angle glaucoma