title: [Performance evaluation of comprehensive treatment of patients with infectious complications of bullet-extremity fractures].
abstract: The objective of the study was to examine the effectiveness of complex treatment of patients with infectious complications of gunshot fractures of limb bones using advanced minimally invasive surgical technologies phased osteosynthesis and new approaches of drug therapy. A prospective, comparative study of the results of examination and treatment of 60 patients with infectious complications of gunshot diaphyseal fractures of the long bones of the limbs treated in hospital Almutavakel (Sana'a, Republic of Yemen) in the period 2009-2011. Patients were randomized and divided into groups depending on the treatment regimen: a comparison (30 patients) received traditional scheme in which only apply external fixation devices or metal obsolete models and basic (30 patients), received treatment for advanced techniques include minimally invasive surgical sanitation of infected fracture zone followed by differentiated (depending on the size of the existing bone defect) tactics of consistent and gradual minimally invasive functionally stable osteosynthesis with modern APS and implants on a background of conservative therapy consisting of Cycloferon. The study showed a high clinical and cost-effectiveness of improved methods compared to traditional, that allows to recommend it for the provision of specialized medical care in the treatment of patients with infectious and complicated gunshot fractures of the long bones of the limbs.
authors.affiliation: Chair of Clinical and Laboratory diagnostics of I.I. Mechnikov Northwest State Medical University, Health Ministry of Russia, Moscow; Chair of Maxillofacial Surgery and Surgical Dentistry of Saint-Petersburg State University; Chair of Microbiology, Immunology and Infectious Diseases of Yaroslav Mudryi Novgorod State University, Velikiy Novgorod.
authors.forename: V K
authors.initials: VK
authors.lastname: Kozlov
authors.affiliation: Chair of Traumatology, Orthopedics and Rehabilitation of Russian Medical Academy of Postgraduate Education, Health Ministry of Russia, Moscow.
authors.forename: A M
authors.initials: AM
authors.lastname: Chililov
authors.affiliation: Department of Orthopedics and Arthrology of A.V. Vishnevsky Institute of Surgery, Health Ministry of Russia, Moscow, Russia.
authors.forename: B G
authors.initials: BG
authors.lastname: Akhmedov
mesh_terms: D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D005260:Female; D005592:Fracture Fixation; D050723:Fractures, Bone / Q000150:complications* / Q000601:surgery; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D014946:Wound Infection / Q000209:etiology / Q000628:therapy*; D014948:Wounds, Gunshot / Q000150:complications* / Q000601:surgery; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D007166:Immunosuppressive Agents