title: Respiratory epithelial adenomatoid hamartoma of the olfactory groove: A report of 4 cases and a review of the literature.
abstract: Respiratory epithelial adenomatoid hamartoma (REAH) is a rare benign lesion that affects the nasal cavity and paranasal sinuses. We present 4 cases of REAH that involved the olfactory clefts; 1 case was bilateral. Each of the cases was treated surgically, and no recurrence was observed. Most reports have indicated that REAH occurs in the presence of sinonasal inflammation, particularly nasal polyposis, yet all 4 of our cases occurred in the absence of concurrent rhinosinusitis. This suggests that the etiology of REAH is multifactorial. In addition, we review the literature on REAH, and we discuss its presentation, differential diagnosis, radiology, histopathology, and underlying treatment principles.
authors.affiliation: Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
authors.forename: William G
authors.initials: WG
authors.lastname: Albergotti
authors.forename: Alkis J
authors.initials: AJ
authors.lastname: Psaltis
authors.forename: Rodney J
authors.initials: RJ
authors.lastname: Schlosser
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006222:Hamartoma / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009296:Nasal Cavity / Q000000981:diagnostic imaging; D009298:Nasal Polyps / Q000000981:diagnostic imaging / Q000473:pathology; D009668:Nose Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D009830:Olfactory Bulb / Q000000981:diagnostic imaging; D010256:Paranasal Sinuses / Q000000981:diagnostic imaging; D020545:Respiratory Mucosa / Q000000981:diagnostic imaging / Q000473:pathology