title: Assembly of 3-Sulfenylbenzofurans and 3-Sulfenylindoles by Palladium-Catalyzed Cascade Annulation/Arylthiolation Reaction.
abstract: A novel and efficient palladium-catalyzed cascade annulation/arylthiolation reaction has been developed to afford functionalized 3-sulfenylbenzofuran and 3-sulfenylindole derivatives in moderate to good yields from readily available 2-alkynylphenols and 2-alkynylamines in ionic liquids. This protocol provides a valuable synthetic tool for the assembly of a wide range of 3-sulfenylbenzofuran and 3-sulfenylindole derivatives with high atom- and step-economy and exceptional functional group tolerance. Moreover, the employment of ionic liquids under mild reaction conditions makes this transformation green and practical. Furthermore, this approach enriched current C-S bond formation chemistry, making a valuable and practical method in synthetic and medicinal chemistry.
authors.affiliation: School of Chemistry and Chemical Engineering and ‡State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
authors.forename: Jianxiao
authors.initials: J
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering and ‡State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
authors.forename: Chunsheng
authors.initials: C
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering and ‡State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
authors.forename: Shaorong
authors.initials: S
authors.lastname: Yang
authors.affiliation: School of Chemistry and Chemical Engineering and ‡State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
authors.forename: Yanni
authors.initials: Y
authors.lastname: An
authors.affiliation: School of Chemistry and Chemical Engineering and ‡State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
authors.forename: Wanqing
authors.initials: W
authors.lastname: Wu
authors.affiliation: School of Chemistry and Chemical Engineering and ‡State Key Laboratory of Luminescent Materials and Devices, South China University of Technology , Guangzhou 510640, China.
authors.forename: Huanfeng
authors.initials: H
authors.lastname: Jiang