title: Orbital inflammation: Corticosteroids first.
abstract: Orbital inflammation is common, and may affect all ages and both genders. By combining a thorough history and physical examination, targeted ancillary laboratory testing and imaging, a presumptive diagnosis can often be made. Nearly all orbital inflammatory pathology can be empirically treated with corticosteroids, thus obviating the need for histopathologic diagnosis prior to initiation of therapy. In addition, corticosteroids may be effective in treating concurrent systemic disease. Unless orbital inflammation responds atypically or incompletely, patients can be spared biopsy.
authors.affiliation: Ophthalmic Plastic Surgery Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Lora R
authors.initials: LR
authors.lastname: Dagi Glass
authors.affiliation: Ophthalmic Plastic Surgery Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: suzanne_freitag@meei.harvard.edu.
authors.forename: Suzanne K
authors.initials: SK
authors.lastname: Freitag
mesh_terms: D019468:Disease Management; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D016727:Orbital Pseudotumor / Q000188:drug therapy*
chemical_list: D005938:Glucocorticoids
keywords: ancillary testing; biopsy; corticosteroid; orbital inflammation; targeted therapy