title: Hox Genes and the Hindbrain: A Study in Segments.
abstract: The hindbrain develops through a process of segmentation which is coupled with the ordered expression of Hox genes to generate regional diversity of key neural and craniofacial derivatives during head development. This is a fundamental feature governed by a gene regulatory network conserved to the base of vertebrate evolution.
authors.affiliation: Stowers Institute for Medical Research, Kansas City, Missouri, USA; Department of Anatomy & Cell Biology, Kansas University Medical School, Kansas City, Kansas, USA. Electronic address: rek@stowers.org.
authors.forename: Robb
authors.initials: R
authors.lastname: Krumlauf
mesh_terms: D000818:Animals; D005075:Biological Evolution; D019521:Body Patterning / Q000235:genetics*; D018507:Gene Expression Regulation, Developmental; D053263:Gene Regulatory Networks; D005801:Genes, Homeobox / Q000235:genetics*; D006801:Humans; D012249:Rhombencephalon / Q000196:embryology*
keywords: Axial patterning; Gene regulation; Hindbrain segmentation; Homeobox genes; Hox genes; Neural development; Patterning and regulatory networks; Vertebrate evolution