title: High rate of mortality in Spanish community-dwelling population aged 85 with atrial fibrillation after three years of follow-up: The Octabaix study.
abstract: OBJECTIVE
  To assess the possible association between three-year global mortality and atrial fibrillation (AF) in 328 community-dwelling participants aged 85 at baseline.
  
  
  METHODS
  Sociodemographic data, comorbidity and geriatric assessment tools, thromboembolic risk, and AF therapy were assessed. We compared the patients who survived with those who died.
  
  
  RESULTS
  At baseline, 41 (12.5%) of participants had permanent AF, and 13 of them died (31.7%) after the three-year follow-up period compared with 44 (15.3%) of the rest of cohort (P = 0.01). Cox regression analysis identified two significant clinical variables as independent predictors of three-year risk of global mortality: Lawton Index (hazard ratio 0.82, 95% confidence interval 0.75-0.91) and AF (hazard ratio 1.90, 95% confidence interval 1.01-3.56). None of the other of variables evaluated showed predictive value of global mortality in the AF patients.
  
  
  CONCLUSIONS
  In oldest old community-dwelling participants, AF is an independent risk factor for global mortality after a three-year follow-up period.
authors.affiliation: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute, IDIBELL, L'Hospitalet de Llobregat, Barcelona, Spain. fformiga@bellvitgehospital.cat.
authors.forename: Francesc
authors.initials: F
authors.lastname: Formiga
authors.affiliation: Primary Healthcare Centre 'El Plà' CAP -I, Sant Feliu de Llobregat, Barcelona, Spain.
authors.forename: Assumpta
authors.initials: A
authors.lastname: Ferrer
authors.affiliation: Primary Healthcare Centre 'El Plà' CAP -I, Sant Feliu de Llobregat, Barcelona, Spain.
authors.forename: Delia
authors.initials: D
authors.lastname: Mestre
authors.affiliation: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
authors.forename: Ariadna
authors.initials: A
authors.lastname: Brasé
authors.affiliation: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain.
authors.forename: Laura
authors.initials: L
authors.lastname: Soldevila
authors.affiliation: Geriatric Unit, Internal Medicine Service, Hospital Universitari de Bellvitge, Bellvitge Biomedical Research Institute. IDIBELL, L'Hospitalet de Llobregat, Faculty of Medicine and Health Sciences, Universitat Internacional de Catalunya, Barcelona, Spain.
authors.forename: Xavier
authors.initials: X
authors.lastname: Corbella
mesh_terms: D000367:Age Factors; D000369:Aged, 80 and over; D000375:Aging; D001281:Atrial Fibrillation / Q000175:diagnosis / Q000401:mortality*; D016009:Chi-Square Distribution; D005260:Female; D005500:Follow-Up Studies; D015577:Geriatric Assessment; D006801:Humans; D057187:Independent Living; D053208:Kaplan-Meier Estimate; D016014:Linear Models; D008297:Male; D011379:Prognosis; D016016:Proportional Hazards Models; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013030:Spain / Q000453:epidemiology; D013997:Time Factors
keywords: 80 and over; aged; atrial fibrillation; comorbidity; geriatric assessment; mortality