title: Intracerebral hemorrhage with intraventricular extension and no hydrocephalus may not increase mortality or severe disability.
abstract: This paper aimed to test the hypothesis that intraventricular extension of spontaneous intracerebral hemorrhage (ICH) in the absence of hydrocephalus is not associated with increased mortality or severe disability. We performed a retrospective consecutive cohort study of patients with primary spontaneous ICH who were admitted to a single institution. Multivariate logistic regression analysis was used to assess the association of each variable with functional outcome as measured by the modified Rankin Scale (mRS). A total of 164 patients met our inclusion criteria and were included in the study. Only hydrocephalus (p=0.002) and hematoma volume (p=0.006) were significantly associated with mortality or poor functional outcome (mRS of 3 to 6). In contrast, the presence of intraventricular hematoma was not independently associated with poor functional outcome. The presence of intraventricular extension of ICH in the absence of hydrocephalus may not increase mortality or disability.
authors.affiliation: Department of Neurology, Temple University School of Medicine, Philadelphia, PA, USA; Department of Neurology, Columbia University Medical Center, 177 Ft. Washington Avenue, 8th floor, MHB 8GS, New York, NY 10032, USA; Department of Neurology, Weill Cornell Medical College, New York, NY, USA. Electronic address: am4370@cumc.columbia.edu.
authors.forename: Ali
authors.initials: A
authors.lastname: Mahta
authors.affiliation: Department of Neurology, Temple University School of Medicine, Philadelphia, PA, USA.
authors.forename: Paul M
authors.initials: PM
authors.lastname: Katz
authors.affiliation: Department of Neurology, Weill Cornell Medical College, New York, NY, USA.
authors.forename: Hooman
authors.initials: H
authors.lastname: Kamel
authors.affiliation: Department of Neurology, Temple University School of Medicine, Philadelphia, PA, USA.
authors.forename: S Ausim
authors.initials: SA
authors.lastname: Azizi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002543:Cerebral Hemorrhage / Q000150:complications / Q000401:mortality* / Q000473:pathology*; D015331:Cohort Studies; D005260:Female; D006406:Hematoma / Q000150:complications / Q000401:mortality / Q000473:pathology; D006801:Humans; D006849:Hydrocephalus; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies
keywords: Hydrocephalus; Intracerebral hemorrhage; Intraventricular hemorrhage; Outcome; Prognosis