title: Comparison of intraoperative volume and pressure-controlled ventilation modes in patients who undergo open heart surgery.
abstract: Respiratory problems occur more frequently in patients who undergo open heart surgery. Intraoperative and postoperative ventilation strategies can prevent these complications and reduce mortality. We hypothesized that PCV would have better effects on gas exchange, lung mechanics and hemodynamics compared to VCV in CABG surgery. Our primary outcome was to compare the PaO2/FiO2ratio. Patients were randomized into two groups, (VCV, PCV) consisting of 30 individuals each. Two patients were excluded from the study. I/E ratio was adjusted to 1:2 and, RR:10/min fresh air gas flow was set at 3L/min in all patients. In the VCV group TV was set at 8 mL/kg of the predicted body weight. In the PCV group, peak inspiratory pressure was adjusted to the same tidal volume with the VCV group. PaO2/FiO2 was found to be higher with PCV at the end of the surgery. Time to extubation and ICU length of stay was shorter with PCV. Ppeak was similar in both groups. Pplateau was lower and Pmean was higher at the and of the surgery with PCV compared to VCV. The hemodynamic effects of both ventilation modes were found to be similar. PVC may be preferable to VCV in patients who undergo open heart surgery. However, it would be convenient if our findings are supported by similar studies.
authors.affiliation: Department of Anesthesiology and Reanimation, Kocaeli University of Medical Faculty, Umuttepe, Kocaeli, Turkey. tulayhosten@hotmail.com.
authors.forename: Tülay
authors.initials: T
authors.lastname: Hoşten
authors.affiliation: Department of Anesthesiology and Reanimation, Kocaeli University of Medical Faculty, Umuttepe, Kocaeli, Turkey.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Kuş
authors.affiliation: Department of Anesthesiology and Reanimation, Kocaeli University of Medical Faculty, Umuttepe, Kocaeli, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Gümüş
authors.affiliation: Department of Anesthesiology and Reanimation, Kocaeli University of Medical Faculty, Umuttepe, Kocaeli, Turkey.
authors.forename: Şadan
authors.initials: Ş
authors.lastname: Yavuz
authors.affiliation: Department of Cardiovascular Surgery, Kocaeli University, Umuttepe, Kocaeli, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: İrkil
authors.affiliation: Department of Anesthesiology and Reanimation, Kocaeli University of Medical Faculty, Umuttepe, Kocaeli, Turkey.
authors.forename: Mine
authors.initials: M
authors.lastname: Solak
mesh_terms: D000368:Aged; D001784:Blood Gas Analysis; D001794:Blood Pressure; D006348:Cardiac Surgical Procedures / Q000379:methods*; D003422:Critical Care; D005260:Female; D006439:Hemodynamics; D006801:Humans; D007362:Intensive Care Units; D008168:Lung / Q000502:physiology; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D010100:Oxygen / Q000737:chemistry; D010865:Pilot Projects; D011175:Positive-Pressure Respiration; D011659:Pulmonary Gas Exchange; D012121:Respiration, Artificial / Q000379:methods*; D015656:Respiratory Mechanics; D013990:Tidal Volume
chemical_list: D010100:Oxygen
keywords: Open heart surgery; Oxygenation; PaO2/fiO2 ratio; Pressure controlled; Ventilation; Volume controlled