title: Reinvitation to screening colonoscopy: a randomized-controlled trial of reminding letter and invitation to educational meeting on attendance in nonresponders to initial invitation to screening colonoscopy (REINVITE).
abstract: OBJECTIVE
  The response rate to initial invitation to population-based primary screening colonoscopy within the NordICC trial (NCT 00883792) in Poland is around 50%. The aim of this study was to compare the effect of a reinvitation letter and invitation to an educational intervention on participation in screening colonoscopy in nonresponders to initial invitation.
  
  
  METHODS
  Within the NordICC trial framework, individuals living in the region of Warsaw, who were drawn from Population Registries and assigned randomly to the screening group, received an invitation letter and a reminder with a prespecified screening colonoscopy appointment date. One thousand individuals, aged 55 to 64 years, who did not respond to both the invitation and the reminding letter were assigned randomly in a 1:1 ratio to the reinvitation group (REI) and the educational meeting group (MEET). The REI group was sent a reinvitation letter and reminder 6 and 3 weeks before the new colonoscopy appointment date, respectively. The MEET group was sent an invitation 6 weeks before an educational meeting date. Outcome measures were participation in screening colonoscopy within 6 months and response rate within 3 months from the date of reinvitation or invitation to an educational meeting.
  
  
  RESULTS
  The response rate and the participation rate in colonoscopy were statistically significantly higher in the REI group compared with the MEET group (16.5 vs. 4.3%; P<0.001 and 5.2 vs. 2.1%; P=0.008, respectively).
  
  
  CONCLUSIONS
  A simple reinvitation letter results in a higher response rate and participation rate to screening colonoscopy than invitation to tailored educational meeting in nonresponders to previous invitations. (NCT01183156).
authors.affiliation: aDepartment of Gastroenterological Oncology, the Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology bDepartment of Gastroenterology and Hepatology, Medical Center for Postgraduate Education, Warsaw, Poland.
authors.forename: Malgorzata
authors.initials: M
authors.lastname: Pisera
authors.forename: Michal F
authors.initials: MF
authors.lastname: Kaminski
authors.forename: Ewa
authors.initials: E
authors.lastname: Kraszewska
authors.forename: Maciej
authors.initials: M
authors.lastname: Rupinski
authors.forename: Jaroslaw
authors.initials: J
authors.lastname: Regula
mesh_terms: D001071:Appointments and Schedules; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis*; D015709:Correspondence as Topic; D055088:Early Detection of Cancer / Q000379:methods*; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D010342:Patient Acceptance of Health Care; D010353:Patient Education as Topic; D011044:Poland; D013997:Time Factors