title: Benefit of anticoagulation for the treatment of lower extremity superficial venous thrombosis.
abstract: Superficial venous thrombosis (SVT) of the lower extremity is an acute disorder characterized by thrombosis and inflammation of superficial veins. This most commonly affects varicose veins but can also occur in patients with nonvaricose veins, who may have an underlying condition such as a malignant disease or thrombophilia. It is important to be aware that SVT confers a significant risk for the development of the more serious and debilitating condition of deep venous thrombosis and the potentially life-threatening condition of pulmonary embolism. Recognition of SVT, determination of appropriateness of therapy, and institution of timely therapy are paramount to prevention of deep venous thrombosis and pulmonary embolism in properly selected patients. The objective of this evidence-based summary was to provide clinically applicable information from the current literature and guidelines regarding the best treatment options for SVT. There are no randomized trials that compare the efficacy and outcomes of newer therapies, such as the novel oral anticoagulants and endovenous ablation, with traditional therapies, such as traditional anticoagulant and surgery exclusion, in the treatment of SVT.
authors.affiliation: Division of Vascular Surgery, VA Boston Healthcare System, Boston, Mass; Division of Vascular Surgery, Brigham and Women's Hospital, Boston, Mass; Harvard Medical School, Boston, Mass. Electronic address: joseph.raffetto@med.va.gov.
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Raffetto
authors.affiliation: Division of Cardiology, Boston Medical Center, Boston, Mass; Boston University School of Medicine, Boston, Mass.
authors.forename: Robert T
authors.initials: RT
authors.lastname: Eberhardt
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use*; D006801:Humans; D007866:Leg / Q000098:blood supply*; D011655:Pulmonary Embolism / Q000517:prevention & control; D012307:Risk Factors; D016896:Treatment Outcome; D014648:Varicose Veins / Q000188:drug therapy; D020246:Venous Thrombosis / Q000150:complications / Q000188:drug therapy*
chemical_list: D000925:Anticoagulants