title: [Pleurisy induced by atorvastatin].
abstract: BACKGROUND
  Whereas numerous case reports have described statin-induced lung injuries, statin-induced pleural effusions are uncommon.
  
  
  METHODS
  An 84-year-old man presented with bilateral pleural effusions two years after starting treatment with atorvastatin. No other cause of pleural effusion was found and all symptoms and radiological signs resolved rapidly after discontinuation of the drug. Furthermore, an accidental reintroduction of the treatment resulted in recurrence of the same clinical picture, reinforcing the hypothesis that atorvastatin was responsible for this pleural effusion.
  
  
  CONCLUSIONS
  Pleuropulmonary manifestations in a patient treated with atorvastatin should rapidly evoke an iatrogenic origin and the discontinuation of the drug should be discussed.
authors.affiliation: Département de pneumologie, centre hospitalier universitaire d'Angers, 4, rue Larrey, 49033 Angers cedex 9, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Mansour
authors.affiliation: Service de pneumologie, centre hospitalier de Cholet, 1, rue de Marengo, 49325 Cholet, France.
authors.forename: P
authors.initials: P
authors.lastname: Masson
authors.affiliation: Département de radiologie, centre hospitalier universitaire d'Angers, 4, rue Larrey, 49033 Angers cedex 9, France.
authors.forename: A L
authors.initials: AL
authors.lastname: Gourdier
authors.affiliation: Département de pneumologie, centre hospitalier universitaire d'Angers, 4, rue Larrey, 49033 Angers cedex 9, France; Inserm U1063, stress oxydant et pathologies métaboliques, rue des Capucins, 49100 Angers, France.
authors.forename: F
authors.initials: F
authors.lastname: Gagnadoux
authors.affiliation: Département de pneumologie, centre hospitalier universitaire d'Angers, 4, rue Larrey, 49033 Angers cedex 9, France; Inserm U1063, stress oxydant et pathologies métaboliques, rue des Capucins, 49100 Angers, France. Electronic address: wotrzepizur@chu-angers.fr.
authors.forename: W
authors.initials: W
authors.lastname: Trzepizur
mesh_terms: D000369:Aged, 80 and over; D000069059:Atorvastatin / Q000009:adverse effects*; D006801:Humans; D008297:Male; D010998:Pleurisy / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000473:pathology; D013902:Radiography, Thoracic
chemical_list: D000069059:Atorvastatin
keywords: Atorvastatin; Atorvastatine; Drug-induced pleural effusion; Pleurésie médicamenteuse; Statine; Statins