title: Effect of resistance training on muscular strength and indicators of abdominal adiposity, metabolic risk, and inflammation in postmenopausal women: controlled and randomized clinical trial of efficacy of training volume.
abstract: This study evaluated the effect of resistance training (RT) volume on muscular strength and on indicators of abdominal adiposity, metabolic risk, and inflammation in post-menopausal women (PW). Thirty-two volunteers were randomly allocated into the following three groups: control (CT, no exercise, n = 11), low-volume RT (LV, three sets/exercise, n = 10), and high-volume RT (HV, six sets/exercise, n = 11). The LV and HV groups performed eight exercises at 70 % of one maximal repetition, three times a week, for 16 weeks. Muscular strength and indicators of abdominal adiposity, metabolic risk, and inflammation were measured at baseline and after 16 weeks. No differences were found in baseline measures between the groups. The PW showed excess weight and fat percentage (F%), large waist circumference (WC), high waist-hip ratio (WHR), and hypercholesterolemia and borderline values of glycated hemoglobin (HbA1c%). Following the RT, a similar increase in muscle strength and reduction in F% from baseline were found in both trained groups. In HV, a decrease in total cholesterol, LDL-c, WC, and WHR was noted. Moreover, the HV showed a lower change (delta%) of interleukin-6 (IL-6) when compared to CT (HV = 11.2 %, P 25-75 = -7.6-28.4 % vs. CT = 99.55 %, P 25-75 = 18.5-377.0 %, p = 0.049). In LV, a decrease was noted for HbA1c%. There were positive correlations (delta%) between WHR and IL-6 and between IL-6 and TC. These results suggest that while a low-volume RT improves HbA1c%, F%, and muscular strength, a high-volume RT is necessary to improve indicators of abdominal adiposity and lipid metabolism and also prevent IL-6 increases in PW.
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil. paulo.pradonunes@gmail.com.
authors.forename: Paulo Ricardo Prado
authors.initials: PR
authors.lastname: Nunes
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.
authors.forename: Larissa Corrêa
authors.initials: LC
authors.lastname: Barcelos
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.
authors.forename: Anselmo Alves
authors.initials: AA
authors.lastname: Oliveira
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.
authors.forename: Roberto
authors.initials: R
authors.lastname: Furlanetto Júnior
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.
authors.forename: Fernanda Maria
authors.initials: FM
authors.lastname: Martins
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.
authors.forename: Cláudio Lera
authors.initials: CL
authors.lastname: Orsatti
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.
authors.forename: Elisabete Aparecida Mantovani Rodrigues
authors.initials: EA
authors.lastname: Resende
authors.affiliation: Postgraduate Course of Physical Education, Exercise Biology Laboratory (BioEx), Federal University of Triângulo Mineiro (UFTM), Avenue Tutunas, 490, Uberaba, MG, Brazil.|Department of Sport Sciences, Health Science Institute, Federal University of Triangulo Mineiro (UFTM), Uberaba, Minas Gerais, Brazil.
authors.forename: Fábio Lera
authors.initials: FL
authors.lastname: Orsatti
mesh_terms: D050154:Adiposity / Q000502:physiology*; D000368:Aged; D000375:Aging / Q000502:physiology*; D015415:Biomarkers / Q000378:metabolism; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000378:metabolism*; D008875:Middle Aged; D053580:Muscle Strength / Q000502:physiology; D056128:Obesity, Abdominal / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation*; D017698:Postmenopause; D012307:Risk Factors; D055948:Sarcopenia / Q000378:metabolism / Q000503:physiopathology / Q000534:rehabilitation*; D049629:Waist-Hip Ratio
chemical_list: D015415:Biomarkers; D006442:Glycated Hemoglobin
keywords: Exercise; Glycosylated hemoglobin; Menopause; Obesity; Sarcopenia