title: Hypervirulent emm59 Clone in Invasive Group A Streptococcus Outbreak, Southwestern United States.
abstract: The hyper-virulent emm59 genotype of invasive group A Streptococcus was identified in northern Arizona in 2015. Eighteen isolates belonging to a genomic cluster grouped most closely with recently identified isolates in New Mexico. The continued transmission of emm59 in the southwestern United States poses a public health concern.
authors.forename: David M
authors.initials: DM
authors.lastname: Engelthaler
authors.forename: Michael
authors.initials: M
authors.lastname: Valentine
authors.forename: Jolene
authors.initials: J
authors.lastname: Bowers
authors.forename: Jennifer
authors.initials: J
authors.lastname: Pistole
authors.forename: Elizabeth M
authors.initials: EM
authors.lastname: Driebe
authors.forename: Joel
authors.initials: J
authors.lastname: Terriquez
authors.forename: Linus
authors.initials: L
authors.lastname: Nienstadt
authors.forename: Mark
authors.initials: M
authors.lastname: Carroll
authors.forename: Mare
authors.initials: M
authors.lastname: Schumacher
authors.forename: Mary Ellen
authors.initials: ME
authors.lastname: Ormsby
authors.forename: Shane
authors.initials: S
authors.lastname: Brady
authors.forename: Eugene
authors.initials: E
authors.lastname: Livar
authors.forename: Del
authors.initials: D
authors.lastname: Yazzie
authors.forename: Victor
authors.initials: V
authors.lastname: Waddell
authors.forename: Marie
authors.initials: M
authors.lastname: Peoples
authors.forename: Kenneth
authors.initials: K
authors.lastname: Komatsu
authors.forename: Paul
authors.initials: P
authors.lastname: Keim
mesh_terms: D000328:Adult; D000368:Aged; D015373:Bacterial Typing Techniques; D002999:Clone Cells; D004269:DNA, Bacterial / Q000235:genetics*; D004196:Disease Outbreaks; D005260:Female; D016680:Genome, Bacterial; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D016133:Polymerase Chain Reaction; D012307:Risk Factors; D017422:Sequence Analysis, DNA; D012720:Severity of Illness Index; D015206:Southwestern United States / Q000453:epidemiology; D013290:Streptococcal Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000473:pathology / Q000635:transmission; D013291:Streptococcus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*; D014774:Virulence
chemical_list: D004269:DNA, Bacterial
keywords: Arizona; California; Canada; GAS; Minnesota; Native Americans; New Mexico; Oregon; bacteria; emm59; genomic epidemiology; group A Streptococcus; polytomy WGST; pyogenes; southwestern United States; streptococci