title: Serial amnioinfusions for fetal pulmonary palliation in fetuses with renal failure.
abstract: Fetal lower urinary tract obstruction (LUTO) encompasses a heterogeneous group of congenital pathologies and generally results in oligohydramnios. Fetal intervention (e.g. vesicoamniotic shunting, fetal cystoscopy) has traditionally been reserved for cases with a favorable renal profile, while those with unfavorable renal function have been offered termination or expectant management with the latter leading to high incidence of marked pulmonary hypoplasia, neonatal morbidity and mortality. Here, we describe two cases, which were not candidates for traditional intervention based on abnormal fetal renal function, who elected to proceed with serial amnioinfusions for fetal pulmonary palliation to attenuate the risk of pulmonary hypoplasia.
authors.affiliation: a Women's Center of Texas, Austin Maternal-Fetal Medicine , Austin , TX , USA and.
authors.forename: Sina
authors.initials: S
authors.lastname: Haeri
authors.affiliation: b Specialty for Children, Pediatric Nephrology , Austin , TX , USA.
authors.forename: David H
authors.initials: DH
authors.lastname: Simon
authors.affiliation: b Specialty for Children, Pediatric Nephrology , Austin , TX , USA.
authors.forename: Kartik
authors.initials: K
authors.lastname: Pillutla
mesh_terms: D000015:Abnormalities, Multiple / Q000517:prevention & control*; D000328:Adult; D000653:Amniotic Fluid; D005260:Female; D005315:Fetal Diseases / Q000175:diagnosis / Q000628:therapy*; D005317:Fetal Growth Retardation; D006801:Humans; D007231:Infant, Newborn; D008168:Lung / Q000002:abnormalities*; D008171:Lung Diseases / Q000517:prevention & control*; D008297:Male; D016104:Oligohydramnios / Q000175:diagnosis*; D011247:Pregnancy; D051437:Renal Insufficiency / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy* / Q000652:urine; D016216:Ultrasonography, Prenatal; D001748:Urinary Bladder Neck Obstruction / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*
keywords: Amnioinfusion; fetal lower urinary tract obstruction; oligohydramnios; prematurity; pulmonary hypoplasia