title: Safety and efficacy of coffee enriched with inulin and dextrin on satiety and hunger in normal volunteers.
abstract: OBJECTIVE
  This study assessed the safety and efficacy of a new beverage on suppressing hunger and improving feelings of satiety in healthy volunteers.
  
  
  METHODS
  In the safety study, participants (n = 269) received either 1) a control beverage-coffee alone (group C); 2) the study beverage-coffee, whey protein, inulin, and dextrin (group S); or 3) an inulin-enriched beverage (I group). The study was held over a 7-d period during which participants were required to consume 2 cups of coffee a day.
  
  
  RESULTS
  There were no significant differences between the groups in any reported adverse effects, apart from more abdominal pain after the first cup in group I versus S (P < 0.05).
  
  
  CONCLUSIONS
  This study showed that a coffee beverage enriched with inulin, dextrin, and whey is safe and has possible benefits with regard to feelings of hunger and satiety 2 h after ingestion.
authors.affiliation: Endocrinology Institute, Rabin Medical Center, Beilinson Hospital, Petah-Tikva and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Joelle
authors.initials: J
authors.lastname: Singer
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah-Tikva and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Milana
authors.initials: M
authors.lastname: Grinev
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah-Tikva and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Veronica
authors.initials: V
authors.lastname: Silva
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah-Tikva and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Cohen
authors.affiliation: Department of General Intensive Care and Institute for Nutrition Research, Rabin Medical Center, Beilinson Hospital, Petah-Tikva and the Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel. Electronic address: psinger@clalit.org.il.
authors.forename: Pierre
authors.initials: P
authors.lastname: Singer
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003069:Coffee; D003912:Dextrins / Q000494:pharmacology*; D005260:Female; D006801:Humans; D006815:Hunger / Q000187:drug effects*; D007444:Inulin / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012527:Satiation / Q000187:drug effects*; D055815:Young Adult
chemical_list: D003069:Coffee; D003912:Dextrins; D007444:Inulin
keywords: Coffee; Dextrin; Hunger; Inulin; Leptin; Satiety