title: Allergic BronchoPulmonary Aspergillosis in Nepal.
abstract: Allergic BronchoPulmonary Aspergillosis (ABPA) is clinically under recognized and often misdiagnosed in Nepal. A total of 15 cases of ABPA were enrolled in this case series. Cases were followed up after the 3 months of start of treatment and clinical responses were assessed. The mean age of the patients was 33.06 ± 9.2 yrs. 80% were male. 26.6% patients were empirically on anti-tubercular treatment at the time of presentation. 40% patients were misdiagnosed and already treated as pulmonary Tuberculosis. 10 patients were previously treated as cases of refractory asthma. Majority of patients had significant eosinophillia and raised total serum IgE. All patients required treatment with bronchodilator and systemic steroid. 80% patients underwent remission with the treatment. Pulmonary Tuberculosis and refractory bronchial asthma are common condition that leads to the misdiagnosis of this disease.
authors.affiliation: Department of Pulmonary Medicine, Norvic International Hospital, Kathmandu, Nepal.
authors.forename: N
authors.initials: N
authors.lastname: Agarwal
authors.affiliation: Department of Pulmonary Medicine, Norvic International Hospital, Kathmandu, Nepal.
authors.forename: P
authors.initials: P
authors.lastname: Shrestha
authors.affiliation: Department of Pulmonary Medicine, Norvic International Hospital, Kathmandu, Nepal.
authors.forename: R
authors.initials: R
authors.lastname: Chokhani
mesh_terms: D000328:Adult; D000935:Antifungal Agents / Q000627:therapeutic use*; D001229:Aspergillosis, Allergic Bronchopulmonary / Q000175:diagnosis* / Q000188:drug therapy*; D001993:Bronchodilator Agents / Q000627:therapeutic use*; D003937:Diagnosis, Differential; D003951:Diagnostic Errors; D004359:Drug Therapy, Combination; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000627:therapeutic use*; D006801:Humans; D017964:Itraconazole / Q000627:therapeutic use*; D008297:Male; D009390:Nepal; D011446:Prospective Studies; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000935:Antifungal Agents; D001993:Bronchodilator Agents; D005938:Glucocorticoids; D017964:Itraconazole
keywords: ABPA; bronchial asthma; central bronchiectasis; eosinophil count; serum IgE.