title: Residues and dissipation kinetics of carbendazim and diethofencarb in tomato (Lycopersicon esculentum Mill.) and intake risk assessment.
abstract: Dissipation behaviors and residues of carbendazim and diethofencarb in combination in tomato were investigated. The half-lives were 2.1-3.4 days for carbendazim, and 1.8-3.2 days for diethofencarb at a dose of 1.5 times of the recommended dosage. The residues of carbendazim and diethofencarb were below the maximum residue limits (MRLs) in China one day after application of the combination. The ultimate residues were significantly lower than the maximum permissible intake (MPI) in China at the recommended high dose for both child and adult. The values of the maximum dietary exposure for carbendazim and diethofencarb were 0.26 and 0.27 mg per person per day, respectively. The theoretical maximum daily intake (TMDI) values for carbendazim and diethofencarb were 1.5 and 0.5 mg/day, respectively. The dietary exposure was lower than the MPI, which indicates the harvested tomato samples under the experimental conditions (open field) are safe for human consumption at the recommended high dosage of the wettable powder.
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China. Electronic address: lihuidong8066@163.com.
authors.forename: Huidong
authors.initials: H
authors.lastname: Li
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China.
authors.forename: Hongxia
authors.initials: H
authors.lastname: du
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China.
authors.forename: Liping
authors.initials: L
authors.lastname: Fang
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China.
authors.forename: Zhan
authors.initials: Z
authors.lastname: Dong
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Guan
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Fan
authors.affiliation: Institute of Quality Standard and Test Technology for Agro-products, Shandong Academy of Agricultural Sciences, Jinan, Shandong, 250100, China; Shandong Provincial Key Laboratory of Test Technology on Food Quality and Safety, Jinan, Shandong, 250100, China. Electronic address: czl7274@163.com.
authors.forename: Zilei
authors.initials: Z
authors.lastname: Chen
mesh_terms: D000328:Adult; D000367:Age Factors; D001562:Benzimidazoles / Q000009:adverse effects / Q000378:metabolism*; D002219:Carbamates / Q000009:adverse effects / Q000378:metabolism*; D002648:Child; D002681:China; D004032:Diet; D004784:Environmental Monitoring / Q000379:methods; D005506:Food Contamination; D005638:Fruit / Q000378:metabolism; D005659:Fungicides, Industrial / Q000009:adverse effects / Q000378:metabolism*; D006207:Half-Life; D006801:Humans; D007700:Kinetics; D018551:Solanum lycopersicum / Q000378:metabolism*; D008657:Metabolic Clearance Rate; D008954:Models, Biological; D019055:No-Observed-Adverse-Effect Level; D010575:Pesticides / Q000009:adverse effects / Q000378:metabolism*; D048448:Phenylcarbamates / Q000009:adverse effects / Q000378:metabolism*; D011208:Powders; D018570:Risk Assessment
chemical_list: D001562:Benzimidazoles; D002219:Carbamates; D005659:Fungicides, Industrial; D010575:Pesticides; D048448:Phenylcarbamates; D011208:Powders; C070961:diethofencarb; C006698:carbendazim
keywords: Carbendazim; Diethofencarb; Dissipation; Residue; Risk assessment