title: Comparison of ketamine-propofol and remifentanil in terms of hemodynamic variables and patient satisfaction during monitored anaesthesia care.
abstract: BACKGROUND
  This study aimed to compare remifentanil and ketamine-propofol in terms of hemodynamic response, duration of recovery and patient satisfaction in operative hysteroscopy cases who underwent monitored anaesthesia care in combination with paracervical block.
  
  
  METHODS
  Monitored anaesthesia care was used in 60 ASA I-II female patients. The patients were divided into two groups as remifentanil (Group R) and ketamine-propofol (Group K-P). The hemodynamic effects of remifentanil and ketamine-propofol, and duration of recovery were recorded and compared. The patient satisfaction was also recorded and the two groups were compared.
  
  
  RESULTS
  Age, body mass, ASA status, duration of anaesthesia and type of surgery were found to be similar between groups. The time of the Aldrete score reaching ≥ 9 was found to be shorter in Group R when compared with Group KP (Group R: 4.1 ± 1.9 min, Group K-P: 6.1 ± 2.6 min) (P< 0.05). The incidence of postoperative nausea and vomiting was found to be significantly higher in the remifentanil group (P ≤ 0.05). When the groups were compared in terms of patient satisfaction, in both groups this was found to be similar.
  
  
  CONCLUSIONS
  Sedation with remifentanil combined with a paracervical block during monitored anaesthesia care provides early recovery with effective sedation and analgesia in hysteroscopy procedures.
authors.affiliation: Department of Anaesthesiology, Kocaeli Derince Education and Research Hospital, Kocaeli, Turkey. serdenish@yahoo.com.
authors.forename: Sema
authors.initials: S
authors.lastname: Oncul
authors.forename: Elif Atar
authors.initials: EA
authors.lastname: Gaygusuz
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yilmaz
authors.forename: Hasan
authors.initials: H
authors.lastname: Terzi
authors.forename: Canan
authors.initials: C
authors.lastname: Balci
mesh_terms: D000293:Adolescent; D000328:Adult; D000762:Anesthesia Recovery Period; D000778:Anesthetics, Dissociative / Q000009:adverse effects; D018686:Anesthetics, Intravenous / Q000009:adverse effects; D016292:Procedural Sedation; D005260:Female; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D015907:Hysteroscopy / Q000379:methods; D007649:Ketamine / Q000009:adverse effects; D008875:Middle Aged; D016343:Monitoring, Intraoperative; D009407:Nerve Block; D017060:Patient Satisfaction; D010880:Piperidines / Q000009:adverse effects; D020250:Postoperative Nausea and Vomiting / Q000453:epidemiology; D015742:Propofol / Q000009:adverse effects; D011446:Prospective Studies; D000077208:Remifentanil; D015656:Respiratory Mechanics / Q000187:drug effects; D055815:Young Adult
chemical_list: D000778:Anesthetics, Dissociative; D018686:Anesthetics, Intravenous; D010880:Piperidines; D007649:Ketamine; D000077208:Remifentanil; D015742:Propofol
keywords: ketamine; monitored anaesthesia care; opioids; outpatient surgery; propofol; remifentanil; sedatives