title: Autoimmune Hemolytic Anemia Triggered by Infection with Human Parvovirus B19 after Total Abdominal Colectomy for Ulcerative Colitis.
abstract: A 50-year-old man was admitted to our hospital for an adhesive ileus 14 years after total abdominal colectomy for ulcerative colitis (UC). The ileus decreased with conservative treatment, however, autoimmune hemolytic anemia (AIHA) was diagnosed due to worsening anemia, a positive direct Coombs test, low haptoglobin, high lactase dehydrogenase, reticulocytosis, and an increase in the erythroblastic series in a bone-marrow examination. Human parvovirus B19 (PV-B19) IgM and PV-B19 DNA were present, indicating the development of AIHA triggered by an infection with PV-B19. The patient is currently being monitored after spontaneous remission. This is the first report of UC after total abdominal colectomy complicated by AIHA triggered by PV-B19 infection.
authors.affiliation: Department of Gastroenterology, Muroran City General Hospital, Japan.
authors.forename: Tomoya
authors.initials: T
authors.lastname: Iida
authors.forename: Shuji
authors.initials: S
authors.lastname: Satoh
authors.forename: Suguru
authors.initials: S
authors.lastname: Nakagaki
authors.forename: Haruo
authors.initials: H
authors.lastname: Shimizu
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kaneto
mesh_terms: D000744:Anemia, Hemolytic, Autoimmune / Q000209:etiology* / Q000821:virology; D003082:Colectomy / Q000009:adverse effects* / Q000379:methods; D003093:Colitis, Ulcerative / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010322:Parvoviridae Infections / Q000150:complications* / Q000188:drug therapy / Q000276:immunology; D016732:Parvovirus B19, Human / Q000276:immunology / Q000472:pathogenicity*; D011239:Prednisolone / Q000008:administration & dosage; D012075:Remission, Spontaneous; D016896:Treatment Outcome; D057832:Watchful Waiting
chemical_list: D011239:Prednisolone