title: Metastatic pilomatrix carcinoma: Not so rare after all? A case report and review of the literature.
abstract: Pilomatrixoma is a slowly growing benign tumor of the dermal hair cells. Metastatic disease is exceptionally rare. Pilomatrixoma can occur at any age, but most patients are older than 40 years at presentation. Approximately 60% of these lesions occur in the head and neck region. Their size is usually about 4 cm at the time of presentation. Surgical excision with adequate margins is still the preferred treatment. We report a case of an aggressive malignant metastatic pilomatrixoma in a 43-year-old woman who underwent multiple extensive local resections. However, she died within 4 months of presentation.
authors.affiliation: Department of General Surgery, Royal Brisbane and Women's Hospital, Herston, Queensland, Australia. danielwalker79@hotmail.com.
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Walker
authors.forename: Samuel
authors.initials: S
authors.lastname: Dowthwaite
authors.forename: Drew
authors.initials: D
authors.lastname: Cronin
authors.forename: Tristan
authors.initials: T
authors.lastname: Molden-Hauer
authors.forename: Brent
authors.initials: B
authors.lastname: McMonagle
mesh_terms: D000328:Adult; D002277:Carcinoma / Q000150:complications / Q000473:pathology*; D017809:Fatal Outcome; D005260:Female; D006201:Hair Diseases / Q000150:complications / Q000473:pathology*; D006258:Head and Neck Neoplasms / Q000150:complications / Q000473:pathology*; D006801:Humans; D019547:Neck Pain / Q000209:etiology; D009362:Neoplasm Metastasis; D018296:Pilomatrixoma / Q000150:complications / Q000473:pathology*; D012878:Skin Neoplasms / Q000150:complications / Q000473:pathology*