title: Efficacy of pomades containing different percentages of enilconazole in the treatment of bovine dermatophytosis.
abstract: BACKGROUND
  Enilconazole is a broad-spectrum topical antimycotic agent used for the management of bovine dermatophytosis.
  
  
  OBJECTIVE
  To investigate the efficacy of pomades containing different concentrations of enilconazole for the treatment of bovine dermatophytosis.
  
  
  METHODS
  Dermatophytosis was confirmed in 120 cattle from farm in Gole region of Turkey. Animals were divided into six groups (n = 20 in each). Pomades containing 1%, 2%, 3%, 4% and 5% enilconazole were applied topically to individual lesions in groups I-V, respectively, once a day for 3 days. Group VI animals were used as a control group. Animals were monitored clinically once a week for a two month period.
  
  
  RESULTS
  Cows treated with pomades containing 4% and 5% enilconazole recovered; adverse topical reactions occurred in 40% and 55% of animals, respectively. The success rate for cows treated with pomades containing 3% enilconazole was 95% and they recovered with no adverse reactions. Success rates for treatment were 25% and 50% for cows treated with pomades containing 1% and 2% enilconazole, respectively. No improvement was observed in the control group.
  
  
  CONCLUSIONS
  Pomades containing 3% enilconazole are recommended for the treatment of bovine dermatophytosis.
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Kafkas University, Pasacayir, Kars, 36100, Turkey.
authors.forename: Ali Haydar
authors.initials: AH
authors.lastname: Kirmizigul
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Kafkas University, Pasacayir, Kars, 36100, Turkey.
authors.forename: Ekin Emre
authors.initials: EE
authors.lastname: Erkilic
authors.affiliation: Department of Microbiology, Faculty of Veterinary Medicine, Kafkas University, Pasacayir, Kars, 36100, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Buyuk
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Kafkas University, Pasacayir, Kars, 36100, Turkey.
authors.forename: Erhan
authors.initials: E
authors.lastname: Gokce
authors.affiliation: Department of Internal Medicine, Faculty of Veterinary Medicine, Kafkas University, Pasacayir, Kars, 36100, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Citil
mesh_terms: D000287:Administration, Topical; D000818:Animals; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy*; D004305:Dose-Response Relationship, Drug; D005260:Female; D007093:Imidazoles / Q000008:administration & dosage / Q000627:therapeutic use*; D014005:Tinea / Q000188:drug therapy / Q000662:veterinary*
chemical_list: D000935:Antifungal Agents; D007093:Imidazoles; C017435:enilconazole