title: [The possibility of treatment of cognitive impairment in the complex therapy of patients with the consequences of cerebral infarction].
abstract: OBJECTIVE
  To study neuropsychological status of inpatients with the consequences of cerebral infarction treated with cortexin and mexidol.
  
  
  METHODS
  We carried out a neurological and neuropsychological examination of 62 patients with the consequences of cerebral infarction treated with cortexin in the dose of 10 mg and mexidol in the dose of 5 mL of 5% solution intravenously during 15 days.
  
  
  CONCLUSIONS
  It has been shown that the use of this drug combination decreasescomplaints and neurological symptoms and significantly improves cognitive and emotional status as well. The more positive changes are related to attention, speed of mental reactions, anxiety and verbal activity. The complex therapy with cortexin and mexidoldecreased neurological deficit and improve cognitive functioning and psychoemotional status thus increasing quality of life and rehabilitation potential of the patients.
authors.affiliation: Saratov State Medical University of the Russian Health Protection, Neurology Chair, Saratov, Russia.
authors.forename: E B
authors.initials: EB
authors.lastname: Kuznetsova
authors.affiliation: Saratov State Medical University of the Russian Health Protection, Neurology Chair, Saratov, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Salina
authors.affiliation: Saratov State Medical University of the Russian Health Protection, Neurology Chair, Saratov, Russia.
authors.forename: I I
authors.initials: II
authors.lastname: Sholomov
mesh_terms: D000368:Aged; D001288:Attention / Q000187:drug effects; D002544:Cerebral Infarction / Q000150:complications* / Q000523:psychology / Q000534:rehabilitation*; D003071:Cognition / Q000187:drug effects; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology; D004359:Drug Therapy, Combination; D004644:Emotions / Q000187:drug effects; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D036341:Intercellular Signaling Peptides and Proteins; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D010455:Peptides / Q000008:administration & dosage / Q000627:therapeutic use*; D010847:Picolines / Q000008:administration & dosage / Q000627:therapeutic use*; D011788:Quality of Life
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D010455:Peptides; D010847:Picolines; C070020:emoxypine succinate; C056590:cortexin