title: The Significance of Bronchoalveolar Lavage Fluid Cytology in Diagnosing Lung Infiltrates in Children.
abstract: OBJECTIVE
  The aim of this research is to show why is it important in diagnosing children with lung infiltrates.
  
  
  METHODS
  Our study included 50 children with lung infiltrates during period 2005-2012, and was conducted on Pediatric Clinic of the University Clinical Center Sarajevo. We sent all cytological BAL analyses to the University Clinical Center Sarajevo. Cytology was performed by direct microscopy. BAL cytology was performed by the principle of sending samples for centrifuging, 12000 revolutions during a 10 min Shandon-cyto spin. Then the centrifuged sample is dried in the air during 1-2 hours, and is then dyed under the May-Grünwald-Giemsa staining, and analyzed under the Olympus BX41 microscope.
  
  
  RESULTS
  Nosocomial pneumonia has occurred in 32% children, acquired pneumonia in 38%, and 30% children had a lung infiltrates. 6 (12%) of children were younger then 1 year old, 23 (46%) children were between 1 to 5 years, 14 (28%) of children were between 5 to 10 ages, and 7 (14%) of children were between 10-15 ages. The most of the changes in observed children took place on the right lung, 34%, while 26% occurred on the left side, 22% were normal and 18% changes have affected both lungs, right and left. Percentage of cells in cytological smear in children with BAL were: cylindrical cells 28%, lung macrophage 26%, lymphocytes 17%, detritus 17% and phlegm 12%. Erythrocyte sedimentation rate (ESR) in children with BAL was up to 10-52%, to 50-30%, while ESR after first hour was above 50-18 %.
  
  
  CONCLUSIONS
  Clinical parameters and local inflammation of the affected lobe are associated with positive bronchoalveolar cytology lavage findings.
authors.affiliation: Pediatric Clinic of the University Clinical Center of Sarajevo, Sarajevo, Bosnia and Herzegovina.
authors.forename: Amina
authors.initials: A
authors.lastname: Selimovic
authors.affiliation: Department for Cardioanesthesiology, Clinic for anesthesiology, reanimatology and intensive care of the University Clinical Center of Sarajevo, Sarajevo, Bosnia and Herzegovina.
authors.forename: Ermina
authors.initials: E
authors.lastname: Mujicic
authors.affiliation: Sarajevo Medical School, Sarajevo School of Science and Technology, Sarajevo, Bosnia and Herzegovina.
authors.forename: Selma
authors.initials: S
authors.lastname: Milisic
authors.affiliation: Clinic for Lung Diseases and TB "Knez Selo", Clinical Center Niš, Serbia.
authors.forename: Tanja
authors.initials: T
authors.lastname: Pejicic
authors.affiliation: Clinic for Lung Diseases and TB "Knez Selo", Clinical Center Niš, Serbia.
authors.forename: Milan
authors.initials: M
authors.lastname: Rancic
authors.affiliation: Pediatric Clinic of the University Clinical Center of Sarajevo, Sarajevo, Bosnia and Herzegovina.
authors.forename: Senka
authors.initials: S
authors.lastname: Mesihovic-Dinarevic
authors.affiliation: Department of Biology, Faculty of Science, University of Sarajevo, Sarajevo, Bosnia and Hezegovina.
authors.forename: Lada
authors.initials: L
authors.lastname: Lukic-Bilela
authors.affiliation: Department of Orthopedic Surgery, General Hospital "Prim.dr.Abdulah Nakaš", Sarajevo, Bosnia and Herzegovina.
authors.forename: Mahir
authors.initials: M
authors.lastname: Moro
mesh_terms: D000293:Adolescent; D001992:Bronchoalveolar Lavage Fluid / Q000166:cytology* / Q000382:microbiology; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D003428:Cross Infection / Q000175:diagnosis* / Q000382:microbiology; D003937:Diagnosis, Differential; D005260:Female; D006776:Hospitals, Pediatric; D006785:Hospitals, University; D006801:Humans; D007223:Infant; D008297:Male; D018410:Pneumonia, Bacterial / Q000175:diagnosis* / Q000382:microbiology; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
keywords: bronchoalveolar lavage; children; lung infiltrates; pneumonia