title: Use of a disposable circumcision suture device versus conventional circumcision: a systematic review and meta-analysis.
abstract: This systematic review assessed the safety and efficacy of the disposable circumcision suture device (DCSD) and conventional circumcision (CC) in the treatment of redundant prepuce and phimosis. Two independent reviewers conducted a literature search for randomized controlled trials (RCTs) using the DCSD and CC for the treatment of redundant prepuce or phimosis in China and abroad. Nine RCTs (1898 cases) were included. Compared with the CC group, the DCSD group had a shorter operative time (standardized mean difference [SMD] = -21.44; 95% confidence intervals [95% CIs] [-25.08, -17.79]; P < 0.00001), shorter wound healing time (SMD = -3.66; 95% CI [-5.46, -1.85]; P < 0.0001), less intraoperative blood loss (SMD = -9.64; 95% CI [-11.37, -7.90]; P < 0.00001), better cosmetic penile appearance (odds ratio [OR] =8.77; 95% CI [5.90, 13.02]; P < 0.00001), lower intraoperative pain score, lower 24-h postoperative pain score, lower incidence of infection, less incision edema, and fewer adverse events. There were no differences between the CC and DCSD groups in the incidences of dehiscence, or hematoma. The results of this meta-analysis indicate that the DCSD appears to be safer and more effective than CC. However, additional high-quality RCTs with larger study populations are needed.
authors.affiliation: Department of Urology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.|Graduate School, Guangxi University of Traditional Chinese Medicine, Nanning 530200, Guangxi, China.
authors.forename: Zhong-Chao
authors.initials: ZC
authors.lastname: Huo
authors.affiliation: Department of Urology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Liu
authors.affiliation: Department of Operating Room, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.
authors.forename: Xiao-Yan
authors.initials: XY
authors.lastname: Li
authors.affiliation: Research Center of Medical Sciences, The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.
authors.forename: Fei
authors.initials: F
authors.lastname: Liu
authors.affiliation: Department of Urology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.
authors.forename: Wen-Ju
authors.initials: WJ
authors.lastname: Fan
authors.affiliation: Graduate School, North China University of Science and Technology, Tangshan 063000, Hebei, China.
authors.forename: Ru-Hua
authors.initials: RH
authors.lastname: Guan
authors.affiliation: Department of Urology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.|Graduate School, Guangxi University of Traditional Chinese Medicine, Nanning 530200, Guangxi, China.
authors.forename: Pei-Feng
authors.initials: PF
authors.lastname: Li
authors.affiliation: Department of Urology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.
authors.forename: De-Yang
authors.initials: DY
authors.lastname: Mo
authors.affiliation: Department of Urology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, Guangxi, China.
authors.forename: Yong-Zhi
authors.initials: YZ
authors.lastname: He
mesh_terms: D002944:Circumcision, Male / Q000295:instrumentation*; D004209:Disposable Equipment; D052816:Foreskin / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D010149:Postoperative Pain; D010413:Penis / Q000601:surgery; D010688:Phimosis / Q000601:surgery; D013537:Sutures