title: [Immunomorphological aspects of miscarriage at late gestational ages].
abstract: OBJECTIVE
  to reveal the morphological features of placentas and to define a role of the lectin pathway for activation of the complement system in the development of premature birth.
  
  
  METHODS
  A complex morphological study was conducted to examine 37 placentas, 25 of which were obtained from women with clinical signs of threatened miscarriage and 12 placentas from apparently healthy pregnant women.
  
  
  RESULTS
  Placental tissue CD59 expression was ascertained to be significantly less in the women with threatened miscarriage than in those having full-term babies.
  
  
  CONCLUSIONS
  Decreased CD59 expression in threatened miscarriage at late gestational ages leads to additional activation of a maternal immune response and serves as a possible predictor for premature birth.
authors.affiliation: Laboratory of Pathomorphology and Electron Microscopy, V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of Russia, Ivanovo, Russia.
authors.forename: O P
authors.initials: OP
authors.lastname: Saryeva
authors.affiliation: Laboratory of Pathomorphology and Electron Microscopy, V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of Russia, Ivanovo, Russia.
authors.forename: L M
authors.initials: LM
authors.lastname: Salakhova
authors.affiliation: Laboratory of Pathomorphology and Electron Microscopy, V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of Russia, Ivanovo, Russia.
authors.forename: L V
authors.initials: LV
authors.lastname: Kulida
authors.affiliation: Laboratory of Pathomorphology and Electron Microscopy, V.N. Gorodkov Ivanovo Research Institute of Maternity and Childhood, Ministry of Health of Russia, Ivanovo, Russia.
authors.forename: A I
authors.initials: AI
authors.lastname: Malyshkina
mesh_terms: D000022:Abortion, Spontaneous / Q000235:genetics* / Q000473:pathology; D000328:Adult; D018957:CD59 Antigens / Q000096:biosynthesis* / Q000235:genetics; D005260:Female; D018507:Gene Expression Regulation, Developmental; D005865:Gestational Age; D006801:Humans; D010920:Placenta / Q000378:metabolism / Q000473:pathology; D011247:Pregnancy; D047928:Premature Birth / Q000235:genetics* / Q000473:pathology
chemical_list: D018957:CD59 Antigens; C051590:CD59 protein, human