title: Detecting influential observations in a model-based cluster analysis.
abstract: Finite mixture models have been used to model population heterogeneity and to relax distributional assumptions. These models are also convenient tools for clustering and classification of complex data such as, for example, repeated-measurements data. The performance of model-based clustering algorithms is sensitive to influential and outlying observations. Methods for identifying outliers in a finite mixture model have been described in the literature. Approaches to identify influential observations are less common. In this paper, we apply local-influence diagnostics to a finite mixture model with known number of components. The methodology is illustrated on real-life data.
authors.affiliation: 1 I-BioStat, Universiteit Hasselt, Hasselt, Belgium.
authors.forename: Liesbeth
authors.initials: L
authors.lastname: Bruckers
authors.affiliation: 1 I-BioStat, Universiteit Hasselt, Hasselt, Belgium.|2 I-Biostat, Katholieke Universiteit Leuven, Leuven, Belgium.
authors.forename: Geert
authors.initials: G
authors.lastname: Molenberghs
authors.affiliation: 1 I-BioStat, Universiteit Hasselt, Hasselt, Belgium.|2 I-Biostat, Katholieke Universiteit Leuven, Leuven, Belgium.
authors.forename: Geert
authors.initials: G
authors.lastname: Verbeke
authors.affiliation: 3 Janssen Pharmaceutica, Beerse, Belgium.
authors.forename: Helena
authors.initials: H
authors.lastname: Geys
mesh_terms: D000465:Algorithms; D000818:Animals; D056808:Biostatistics; D001921:Brain / Q000187:drug effects / Q000502:physiology; D016000:Cluster Analysis; D003198:Computer Simulation; D004569:Electroencephalography / Q000706:statistics & numerical data; D006801:Humans; D016013:Likelihood Functions; D015233:Models, Statistical; D017711:Nonlinear Dynamics; D010599:Pharmacokinetics; D011619:Psychotropic Drugs / Q000494:pharmacology; D051381:Rats
chemical_list: D011619:Psychotropic Drugs
keywords: Local influence; finite mixture model; model-based clustering