title: Integrated profiling methods for identifying the targets of bioactive compounds: MorphoBase and ChemProteoBase.
abstract: Covering: up to the end of 2015.Many useful compounds from natural products have been discovered through phenotype-based screening. However, the target identification process for compounds is laborious and time-consuming. With the development of new equipment and methodologies for biological analyses, a variety of profiling methods that utilize large sets of experimental data have been established. Here, we highlight the utility of our identification approaches, MorphoBase and ChemProteoBase.
authors.affiliation: Chemical Biology Research Group, RIKEN CSRS, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan. hisyo@riken.jp.
authors.forename: Makoto
authors.initials: M
authors.lastname: Muroi
authors.affiliation: Chemical Biology Research Group, RIKEN CSRS, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan. hisyo@riken.jp.
authors.forename: Yushi
authors.initials: Y
authors.lastname: Futamura
authors.affiliation: Chemical Biology Research Group, RIKEN CSRS, 2-1 Hirosawa, Wako-shi, Saitama 351-0198, Japan. hisyo@riken.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Osada
mesh_terms: D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology*; D055808:Drug Discovery; D015394:Molecular Structure
chemical_list: D001688:Biological Products