title: Omega 3 and atrial fibrillation: Where are we?
abstract: Anti-arrhythmic properties of n-3 polyunsaturated fatty acids, at least in part mediated by anti-oxidant, anti-inflammatory and anti-fibrotic power, have been widely proved. Effect of fish oil on atrial fibrillation, both in primary and in secondary prevention and after cardiac surgery, are controversial, mostly due to lack of homogeneity between studies but also due to individual variability in response to fatty acids administration. Inclusion of measurement of incorporation of fish oil into cell membranes, appears to be essential in future studies, to assess their antiarrhythmic effect.
authors.affiliation: Annamaria Martino, Leonardo Calo', Division of Cardiology, Policlinico Casilino, 00169 Rome, Italy.
authors.forename: Annamaria
authors.initials: A
authors.lastname: Martino
authors.affiliation: Annamaria Martino, Leonardo Calo', Division of Cardiology, Policlinico Casilino, 00169 Rome, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Pezzi
authors.affiliation: Annamaria Martino, Leonardo Calo', Division of Cardiology, Policlinico Casilino, 00169 Rome, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Magnano
authors.affiliation: Annamaria Martino, Leonardo Calo', Division of Cardiology, Policlinico Casilino, 00169 Rome, Italy.
authors.forename: Elisa
authors.initials: E
authors.lastname: Salustri
authors.affiliation: Annamaria Martino, Leonardo Calo', Division of Cardiology, Policlinico Casilino, 00169 Rome, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Penco
authors.affiliation: Annamaria Martino, Leonardo Calo', Division of Cardiology, Policlinico Casilino, 00169 Rome, Italy.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Calo'
keywords: Atrial fibrillation; Cardiac surgery; N-3 polyunsaturated fatty acids; Omega-3 index; Upstream therapy