title: [A clinical efficacy of electrode pharmaphoresis in treatment of railway workers with low-back pain].
abstract: OBJECTIVE
  To evaluate clinical efficacy and tolerability of electrode pharmaphoresis using preparations xefocam and mydocalm-richter in railway workers with low-back pain.
  
  
  METHODS
  Authors carried out an open prospective noncomparative study of 16 patients, aged 21-82 years, with spinal osteochondrosis with root syndrome and radiculopathia of the lumbar/sacral spine with pain syndrome regardless of its duration. Treatment efficacy was assessed by the dynamics of pain syndrome severity based on the scores of a self-rated scale completed by the patient and the McGill Pain Questionnaire. Quality-of-life was assessed with the Oswestry Disability Index before and in the end of treatment. Clinical outcome was evaluated with the modified Nurick scale. Electrode pharmaphoresis (the "Farma T.E.B. Trans Epidermal Barrier Physio" apparatus) was administered to all patients using xefocam (solution for injections 8 mg, 2 ml per procedure) and mydocalm-richter (solution for injections 100 mg, 2 ml per injection) in the lumbar/sacral spine.
  
  
  CONCLUSIONS
  The high clinical efficacy of electrode pharmaphoresis using xefocam and mydocalm-richter was shown. The complex restoration study resulted in the reduction of pain syndrome in all patients. Pain severity was reduced to mild grade in 68.8% to the middle of treatment and in 93.8% patients in the end of treatment. As a consequence of pain reduction, the functional activity (quality of self-service, daily activities) increased significantly in 68.8% of patients. Positive treatment effect was noted in 100% of patients, good tolerability of this medication in 87.5%.
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow; Sechenov First Moscow State Medical University, Moscow.
authors.forename: V V
authors.initials: VV
authors.lastname: Popov
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow.
authors.forename: E Yu
authors.initials: EY
authors.lastname: Menenkova
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow.
authors.forename: S N
authors.initials: SN
authors.lastname: Babakhina
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow.
authors.forename: E G
authors.initials: EG
authors.lastname: Bezzubik
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Isakova
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow, Semashko Central Clinical Hospital #2 of the 'Russian Railways', Moscow, Sechenov First Moscow State Medical University, Moscow.
authors.forename: D S
authors.initials: DS
authors.lastname: Lezina
authors.affiliation: Semashko Research Clinical Center of the 'Russian Railways', Moscow, Semashko Central Clinical Hospital #2 of the 'Russian Railways', Moscow, Sechenov First Moscow State Medical University, Moscow.
authors.forename: D V
authors.initials: DV
authors.lastname: Dmukhovski
authors.affiliation: Semashko Central Clinical Hospital #2 of the 'Russian Railways', Moscow.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Merkulov
authors.affiliation: Semashko Central Clinical Hospital #2 of the 'Russian Railways', Moscow; Sechenov First Moscow State Medical University, Moscow.
authors.forename: D M
authors.initials: DM
authors.lastname: Merkulova
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D004566:Electrodes; D004586:Electrophoresis / Q000295:instrumentation / Q000379:methods; D005260:Female; D006801:Humans; D017116:Low Back Pain / Q000188:drug therapy* / Q000209:etiology; D008159:Lumbar Vertebrae; D008161:Lumbosacral Region; D008297:Male; D008875:Middle Aged; D009125:Muscle Relaxants, Central / Q000008:administration & dosage*; D010147:Pain Measurement; D010894:Piroxicam / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011446:Prospective Studies; D011843:Radiculopathy / Q000150:complications / Q000188:drug therapy; D011890:Railroads; D014049:Tolperisone / Q000008:administration & dosage*; D016896:Treatment Outcome; D000078329:Workforce; D055815:Young Adult
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D009125:Muscle Relaxants, Central; D010894:Piroxicam; C059451:lornoxicam; D014049:Tolperisone