title: Reversible Atrial Fibrillation with Bradycardia Associated with Primary Cardiac B-Cell Lymphoma.
abstract: Primary cardiac lymphoma (PCL) only rarely occurs and it is defined as a lymphoma in which the bulk of the tumor is located within the heart and pericardium. A 53-year-old woman was referred due to dyspnea, and an electrocardiogram exhibited atrial fibrillation (AF). Echocardiography revealed no abnormal findings. Scintigraphy and a lymph node biopsy led to a diagnosis of PCL. After the start of chemotherapy, AF was converted to atrial tachycardia prior to sinus rhythm with a first-degree atrioventricular block, which was finally restored to a normal sinus rhythm. PCL is only rarely encountered, but it should be included in the differential diagnosis as a possible cause of AF, and such AF could be reversible if the patient can be treated in a timely manner.
authors.affiliation: Cardiovascular Center, Yokosuka Kyosai Hospital, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Hishikari
authors.forename: Taishi
authors.initials: T
authors.lastname: Kuwahara
authors.forename: Shigeki
authors.initials: S
authors.lastname: Kimura
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Hikita
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Isobe
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D001281:Atrial Fibrillation / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D054537:Atrioventricular Block / Q000150:complications / Q000188:drug therapy*; D001919:Bradycardia / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D003520:Cyclophosphamide / Q000008:administration & dosage; D004317:Doxorubicin / Q000008:administration & dosage / Q000031:analogs & derivatives; D004417:Dyspnea / Q000209:etiology; D004452:Echocardiography; D005260:Female; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D006801:Humans; D016393:Lymphoma, B-Cell / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy; D008875:Middle Aged; D011239:Prednisolone / Q000008:administration & dosage; D011877:Radionuclide Imaging; D000069283:Rituximab / Q000008:administration & dosage; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D014750:Vincristine / Q000008:administration & dosage
chemical_list: D000069283:Rituximab; D014750:Vincristine; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone; C027260:pirarubicin