title: Comparison of performances of femtosecond laser and microkeratome for thin-flap laser in situ keratomileusis.
abstract: To compare the clinical outcomes of femtosecond laser (FS) and microkeratome (MK) for thin-flap in situ keratomileusis (LASIK).
  
  
  
  Data from patients with moderate to high myopia (spherical equivalent, >-4 diopters [D]) who underwent thin-flap LASIK using FS (199 eyes/110 patients) and MK (157 eyes/86 patients) were analyzed in this retrospective study. Preoperative and postoperative data were recorded from day 1 and months 1 and 3, postoperatively. Visual and refractive outcomes were compared for efficacy, safety, predictability, stability, and the efficacy and safety indices.
  
  
  
  Three months postoperatively, more eyes in the FS group had an uncorrected distance visual acuity (UCVA) of 20/40 or better compared to MK group (relative risk [RR] 1.01, 95% confidence interval [CI], 0.97-1.05, P = 0.58); significantly more eyes in FS group had an UCVA of 20/20 or better (RR, 1.26, 95%CI, 1.08-1.48, P = 0.003). Intraoperative bleeding occurred in 5% and 36.7%, respectively, of FS and MK groups. There were no significant differences in the refractive predictability within spherical equivalents of 0.5 D (FS, 72%; MK, 63%) and 1.0 D (FS, 90%; MK, 86%). Both groups showed good stability 3 months, postoperatively. The efficacy index in FS group was 113.4%; that in MK group was 102.5% at 3 months postoperatively (P < 0.05). The safety indices for FS and MK groups at 3 months postoperatively were 116.4% and 108.2%, respectively (P < 0.05).
  
  
  
  Both methods of thin-flap created LASIK were effective, safe, predicable, and stable. FS group had significant improvements in efficacy and safety, confirmed by the efficacy and safety indices, compared to MK group. Lasers Surg. Med. 48:596-601, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Ngamjit
authors.initials: N
authors.lastname: Kasetsuwan
authors.affiliation: Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
authors.forename: Vannarut
authors.initials: V
authors.lastname: Satitpitakul
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Vilavun
authors.initials: V
authors.lastname: Puangsricharern
authors.affiliation: Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
authors.forename: Usanee
authors.initials: U
authors.lastname: Reinprayoon
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Lalida
authors.initials: L
authors.lastname: Pariyakanok
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020731:Keratomileusis, Laser In Situ / Q000295:instrumentation* / Q000379:methods; D008297:Male; D009216:Myopia / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: cornea; refractive surgery