title: [Analysis of life-threatening complications during perioperative period in patients undergoing radical cystectomy with orthotopic neobladder].
abstract: OBJECTIVE
  To investigate the factors influencing life-threatening complications during perioperative period in patients undergoing traditional cystectomy with orthotopic neobladder.
  
  
  METHODS
  To retrospectively analyze the clinical data of 206 cases who underwent radical cystectomy with orthotopic neobladder. Logistic regression analysis was used to analyze the significance of the factors such as age, amount of bleeding, pathological stage, effective supplement of albumin, cardiovascular disease, diabetes mellitus, operation duration, intestinal preparation, etc., on the occurrence of severe complications.
  
  
  RESULTS
  Among the 206 patients who underwent radical cystectomy with orthotopic neobladder, 22 cases (10.7%) had life-threatening complications (intestinal fistula, hemorrhagic shock, severe infection) during the perioperative period, and 9 cases died (mortality rate 4.4%). Logistic regression analysis showed that the elderly age, long operation duration, lack of effective supplement of albumin, diabetes mellitus are independent factors influencing the occurrence of life-threatening complications during the perioperative period of radical cystectomy with orthotopic ileal neobladder (P<0.05 for all), and are risk factors positively correlated with the severe complications.
  
  
  CONCLUSIONS
  The elderly age, long operation duration, lack of effective supplement of albumin, and diabetes mellitus are risk factors of the occurrence of life-threatening complications during the perioperative period in patients undergoing radical cystectomy with orthotopic ileal neobladder, therefore, attention should be paid to this issue.
authors.affiliation: Department of Urology, the Third Affiliated Hospital of Kunming Medical University, Tumor Hospital of Yunnan Province, Kunming Yunnan 650118, China.
authors.forename: H
authors.initials: H
authors.lastname: Yang
authors.forename: Z M
authors.initials: ZM
authors.lastname: Liu
authors.forename: Y H
authors.initials: YH
authors.lastname: Lei
authors.forename: Y
authors.initials: Y
authors.lastname: Qin
authors.forename: L Z
authors.initials: LZ
authors.lastname: Meng
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.forename: L B
authors.initials: LB
authors.lastname: Hu
authors.forename: Y
authors.initials: Y
authors.lastname: Yang
mesh_terms: D000367:Age Factors; D000368:Aged; D000418:Albumins / Q000008:administration & dosage; D015653:Cystectomy / Q000009:adverse effects* / Q000379:methods / Q000401:mortality; D048909:Diabetes Complications; D006801:Humans; D007082:Ileum; D061646:Operative Time; D059035:Perioperative Period; D011183:Postoperative Complications / Q000209:etiology* / Q000401:mortality; D012044:Regression Analysis; D012189:Retrospective Studies; D012307:Risk Factors; D013997:Time Factors; D001749:Urinary Bladder Neoplasms; D014547:Urinary Diversion; D016476:Urinary Reservoirs, Continent
chemical_list: D000418:Albumins