title: Comparative multidimensional assessment of laryngeal function and quality of life after radiotherapy and laser surgery for early glottic cancer.
abstract: This study was designed to comparatively assess laryngeal function and quality of life (QOL) of patients after laser surgery (LS) or radiotherapy (RT) for early glottic cancer.
  
  
  
  Sixty-four patients with T1 glottic cancer treated with RT or type II cordectomy underwent both subjective and objective vocal assessments. The LS group was divided into the following: (1) vaporization with defocused mode (laser surgery [LS]-Vap); and (2) excision with focused mode using lower power (LS-Ex).
  
  
  
  Auditory-perceptual evaluation and videostroboscopic images in the LS-Ex group worsened shortly after treatment and time-dependent recovery was quicker than in the LS-Vap group. The LS-Ex group showed equivalent posttherapeutic vocal function with the RT group by acoustics, aerodynamics, and self-assessment questionnaire analysis, whereas the LS-Vap group showed statistically significant worse function.
  
  
  
  The multidimensional assessment showed that early glottic cancer could be successfully treated by either RT or LS-Ex with equivalent posttherapeutic laryngeal function and QOL. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1085-1090, 2016.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Takeyuki
authors.initials: T
authors.lastname: Kono
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Koichiro
authors.initials: K
authors.lastname: Saito
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Haruna
authors.initials: H
authors.lastname: Yabe
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Uno
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Kaoru
authors.initials: K
authors.lastname: Ogawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D015331:Cohort Studies; D055088:Early Detection of Cancer; D005260:Female; D005931:Glottis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery*; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010700:Phonetics; D011379:Prognosis; D012189:Retrospective Studies; D057566:Self Report; D013065:Speech Intelligibility; D013068:Speech Production Measurement; D016896:Treatment Outcome; D014827:Vocal Cords / Q000601:surgery; D014833:Voice Quality
keywords: early glottic cancer; laser surgery; multidimensional assessment; radiotherapy; vocal function