title: Catheter-directed thrombolysis in management of postpartum lower limb deep venous thrombosis - A case series.
abstract: Deep vein thrombosis (DVT) is a major health problem in pregnancy and postpartum period. Catheter-directed thrombolysis (CDT) is safe and effective in the management of symptomatic DVT. Value of CDT in postpartum DVT is not fully evaluated. We describe five patients presenting with acute iliofemoral DVT in their early postpartum period who were treated with mechanical thromboaspiration and CDT. The CDT was done using streptokinase infusion and unfractionated heparin. Percutaneous angioplasty was done in patients with symptomatic residual lesion following thrombolysis. Patients were discharged with oral anticoagulant and compression stockings. This approach was successful in all five cases. Percutaneous endovascular therapy using CDT, mechanical thromboaspiration, and balloon angioplasty is safe and effective in iliofemoral DVT in postpartum period.
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore, Karnataka, 560069, India.
authors.forename: B C
authors.initials: BC
authors.lastname: Srinivas
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore, Karnataka, 560069, India. Electronic address: dr_soumyapatra@rediffmail.com.
authors.forename: Soumya
authors.initials: S
authors.lastname: Patra
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore, Karnataka, 560069, India.
authors.forename: C M
authors.initials: CM
authors.lastname: Nagesh
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore, Karnataka, 560069, India.
authors.forename: Babu
authors.initials: B
authors.lastname: Reddy
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences & Research, Bangalore, Karnataka, 560069, India.
authors.forename: C N
authors.initials: CN
authors.lastname: Manjunath
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002406:Catheterization, Peripheral; D005260:Female; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply*; D011247:Pregnancy; D013300:Streptokinase / Q000627:therapeutic use; D015912:Thrombolytic Therapy / Q000379:methods*; D014568:Urokinase-Type Plasminogen Activator / Q000627:therapeutic use; D020246:Venous Thrombosis / Q000628:therapy*; D055815:Young Adult
chemical_list: D000925:Anticoagulants; D006493:Heparin; D013300:Streptokinase; D014568:Urokinase-Type Plasminogen Activator
keywords: Angioplasty; Catheter-directed thrombolysis; Deep vein thrombosis; Mechanical thromboaspiration; Postpartum