title: [Correlation Analysis Between Common Peaks of Angelica sinensis HPLC Fingerprint and Mineral Elements in Its Growing Soil].
abstract: OBJECTIVE
  To investigate the correlation between common peaks of Angelica sinensis HPLC fingerprint and mineral elements in its growing soil.
  
  
  METHODS
  The fingerprints of 120 batches of Angelica sinensis from 12 habitats were determined by HPLC. The contents of Pb, As, Cr, Sb, Hg, Cu, Cd, Ni, Zn, Mg, Mn, Ca, Fe, Na and K in corresponding soil were determined by ICP-MS and AAS. Bivariate and multiple linear regression were used to analyze the correlation.
  
  
  RESULTS
  There were significant ( P < 0. 01 or P < 0.05) positive and negative correlation between many common peaks in HPLC fingerprint of Angelica sinensis and mineral elements in its growing soil. The contribution of mineral elements in soil on peak 1 were Zn > K > Sb > Fe > Na; on peak 6 (3-butylphthalide) were Mn > Mg > Ca; on peak 7 were Cr > Zn; on peak 8 were Mn > Na; on peak 11 were As > K > Fe > Cd; on peak 12 were Zn > Mn > K; on peak 13 (Z-butylidenephthalide) were Mn > Zn > Cd; on peak 15 were Zn > K; on peak 16 were Fe > Ni; on peak 17 were Zn > Mn > Ni > Fe > K; on peak 18 were Zn > Na; peaks 2,3 (ferulic acid), 4 and 14 (Z-ligustilide) was mainly affected by As, Zn, Sb and Cu, respectively.
  
  
  CONCLUSIONS
  The relationship between HPLC fingerprint peak of Angelica sinensis and mineral elements in its growing soil shows complexity, multiplicity and interactivity, which should be selectively examined during manuring micronutrient fertilizer and Angelica sinensis cultivation.
authors.forename: Jun-xia
authors.initials: JX
authors.lastname: Ding
authors.forename: Zhi-rong
authors.initials: ZR
authors.lastname: Gu
authors.forename: Ya-li
authors.initials: YL
authors.lastname: Wang
authors.forename: Ya-ya
authors.initials: YY
authors.lastname: Zhang
authors.forename: Yao-peng
authors.initials: YP
authors.lastname: Wang
authors.forename: Yu-jing
authors.initials: YJ
authors.lastname: Sun
mesh_terms: D029971:Angelica sinensis / Q000737:chemistry*; D002851:Chromatography, High Pressure Liquid; D017753:Ecosystem; D016014:Linear Models; D008903:Minerals / Q000737:chemistry; D010946:Plants, Medicinal / Q000737:chemistry*; D012987:Soil / Q000737:chemistry*; D013057:Spectrum Analysis; D014131:Trace Elements / Q000737:chemistry
chemical_list: D008903:Minerals; D012987:Soil; D014131:Trace Elements