title: An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy.
abstract: An injectable and self-healing collagen-gold hybrid hydrogel is spontaneously formed by electrostatic self-assembly and subsequent biomineralization. It is demonstrated that such collagen-based hydrogels may be used as an injectable material for local delivery of therapeutic agents, showing enhanced antitumor efficacy.
authors.affiliation: State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, P. R. China.|Hebei Key Laboratory of Applied Chemistry, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, P. R. China.
authors.forename: Ruirui
authors.initials: R
authors.lastname: Xing
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Center for Mesoscience, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, P. R. China.|Hebei Key Laboratory of Applied Chemistry, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, P. R. China.
authors.forename: Tifeng
authors.initials: T
authors.lastname: Jiao
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Center for Mesoscience, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, P. R. China.|Hebei Key Laboratory of Applied Chemistry, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, P. R. China.
authors.forename: Kai
authors.initials: K
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, P. R. China.|Hebei Key Laboratory of Applied Chemistry, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, P. R. China.
authors.forename: Ruiyun
authors.initials: R
authors.lastname: Zhang
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Center for Mesoscience, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Qianli
authors.initials: Q
authors.lastname: Zou
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Center for Mesoscience, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Guanghui
authors.initials: G
authors.lastname: Ma
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|Center for Mesoscience, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Xuehai
authors.initials: X
authors.lastname: Yan
mesh_terms: D000818:Animals; D003094:Collagen / Q000008:administration & dosage / Q000737:chemistry*; D006046:Gold / Q000008:administration & dosage / Q000737:chemistry*; D020100:Hydrogels / Q000008:administration & dosage* / Q000737:chemistry*; D007267:Injections; D051379:Mice; D008819:Mice, Nude; D009369:Neoplasms / Q000188:drug therapy / Q000628:therapy*; D010778:Photochemotherapy / Q000379:methods*; D013696:Temperature
chemical_list: D020100:Hydrogels; D006046:Gold; D003094:Collagen
keywords: antitumor therapy; collagen hydrogels; electrostatic self-assembly; in situ sustained release; injectable and self-healing properties