title: Transformative therapy in hypophosphatasia.
authors.affiliation: Department of Human Metabolism, University of Sheffield, Sheffield, UK.
authors.forename: Nick
authors.initials: N
authors.lastname: Bishop
authors.affiliation: Department of Endocrinology, The Children's Hospital at Westmead, Westmead, New South Wales, Australia.|Department of Paediatrics and Child Health, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Craig F
authors.initials: CF
authors.lastname: Munns
authors.affiliation: Department of Pediatrics, Osaka University, Graduate School of Medicine, Suita, Osaka, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Ozono
mesh_terms: D000469:Alkaline Phosphatase / Q000008:administration & dosage / Q000097:blood / Q000627:therapeutic use; D015415:Biomarkers / Q000097:blood; D002648:Child; D002675:Child, Preschool; D056947:Enzyme Replacement Therapy / Q000379:methods*; D006801:Humans; D007014:Hypophosphatasia / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy*; D007074:Immunoglobulin G / Q000008:administration & dosage / Q000627:therapeutic use; D007223:Infant; D007231:Infant, Newborn; D007279:Injections, Subcutaneous; D011993:Recombinant Fusion Proteins / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D015415:Biomarkers; D007074:Immunoglobulin G; D011993:Recombinant Fusion Proteins; D000469:Alkaline Phosphatase; C570710:asfotase alfa
keywords: Bone Disease; Bone Metabolism; Metabolic; Musculo-Skeletal; Therapeutics