title: [IRON OVERLOAD: BETTER UNDERSTANDING, BETTER CARE].
abstract: Chronic iron overload, either of genetic (hemochromatoses) or acquired (transfusions) origin, leads to frequent disorders, affecting both the quality of life and life expectancy. Major recent advances in the knowledge of iron metabolism, together with advances in biology, imaging and drug design have already significantly improved the diagnostic and therapeutic approaches. These conceptual and technological ameliorations should, in the near future, continue to benefit the clinical management of iron overloaded patients.
authors.forename: Pierre
authors.initials: P
authors.lastname: Brissot
mesh_terms: D019587:Dietary Supplements; D020022:Genetic Predisposition to Disease; D006432:Hemochromatosis / Q000235:genetics; D064451:Hepcidins / Q000008:administration & dosage*; D006801:Humans; D007502:Iron Chelating Agents / Q000008:administration & dosage*; D019190:Iron Overload / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000235:genetics; D008017:Life Expectancy; D011379:Prognosis; D011788:Quality of Life; D012307:Risk Factors; D065227:Transfusion Reaction; D016896:Treatment Outcome
chemical_list: D064451:Hepcidins; D007502:Iron Chelating Agents