title: Potential brain language reorganization in a boy with refractory epilepsy; an fNIRS-EEG and fMRI comparison.
abstract: As part of a presurgical investigation for a resection of a tumor located in the left temporal brain region, we evaluated pre- and postsurgical language lateralization in a right-handed boy with refractory epilepsy. In this study, we compared functional near infrared spectroscopy (fNIRS) results obtained while the participant performed expressive and receptive language tasks with those obtained using functional magnetic resonance imaging (fMRI). This case study illustrates the potential for NIRS to contribute favorably to the localization of language functions in children with epilepsy and cognitive or behavioral problems and its potential advantages over fMRI in presurgical assessment. Moreover, it suggests that fNIRS is sensitive in localizing an atypical language network or potential brain reorganization related to epilepsy in young patients.
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada.
authors.forename: Phetsamone
authors.initials: P
authors.lastname: Vannasing
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada.
authors.forename: Isotta
authors.initials: I
authors.lastname: Cornaggia
authors.affiliation: Division of Child Neurology, CHU Sainte-Justine, Montreal, Quebec, Canada.
authors.forename: Catherine
authors.initials: C
authors.lastname: Vanasse
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada.
authors.forename: Julie
authors.initials: J
authors.lastname: Tremblay
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Division of Child Neurology, CHU Sainte-Justine, Montreal, Quebec, Canada.
authors.forename: Paola
authors.initials: P
authors.lastname: Diadori
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Division of Child Neurology, CHU Sainte-Justine, Montreal, Quebec, Canada.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Perreault
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Psychology Department, Centre de Recherche de Neuropsychologie et Cognition (CERNEC), Université de Montréal, Quebec, Canada.
authors.forename: Maryse
authors.initials: M
authors.lastname: Lassonde
authors.affiliation: CHU Sainte-Justine Research Center, Montreal, Quebec, Canada; Psychology Department, Centre de Recherche de Neuropsychologie et Cognition (CERNEC), Université de Montréal, Quebec, Canada.
authors.forename: Anne
authors.initials: A
authors.lastname: Gallagher
keywords: EEG; Language localization; Refractory epilepsy; fMRI; fNIRS