title: [Determination of 41 pesticides in vegetables and fruits by GPC-GC-MS/MS].
abstract: OBJECTIVE
  A method for the determination of 41 pesticides including 26 organophosphorus pesticides, 6 kinds of carbamate, 7 pryethoids insecticides, 1 kinds of organochlorine and fungicide in vegetables and fruits, was established based on optimized QuEChERS with on line gel permeation chromatography-gas chromatography-mass spectrometry (GPC-GC-MS/MS).
  
  
  METHODS
  The method obtained the optimized conditions by comparing different methods of extraction and purification. The analytes were extracted from the samples using acetonitrile-buffer of acetic acid and sodium acetate. Then the extracts were determined by GC-MS/MS in multireaction monitoring (MRM) mode after being cleaned up with mixed solid-phase dispersion. And the external standard method was applied to quantify.
  
  
  RESULTS
  All the 41 pesticides had good linearity in the ranges of 2-200 ng/mL with the correlation coefficients higher than 0.995. The average recoveries of the most of 41 pesticides in celery and apple were in the range of 71.0%-125.4% at the spiked levels of 5, 10 and 50 μg/kg,with relative standard deviations (RSDs) of 0.34%-15.0%. The limits of quantification (LOQs) of the method at the spiked levels of 5 μg/kg were 0.107-10.100 μg/kg.
  
  
  CONCLUSIONS
  The method is simple, rapid, sensitive and specific.
authors.forename: Lihui
authors.initials: L
authors.lastname: Feng
authors.forename: Shuo
authors.initials: S
authors.lastname: Wang
authors.lastname: Zhang Xiangming
authors.forename: Hongxia
authors.initials: H
authors.lastname: Mao
mesh_terms: D000097:Acetonitriles; D005506:Food Contamination / Q000032:analysis*; D005638:Fruit / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods*; D010573:Pesticide Residues / Q000032:analysis*; D010575:Pesticides; D053719:Tandem Mass Spectrometry / Q000379:methods; D014675:Vegetables / Q000737:chemistry*
chemical_list: D000097:Acetonitriles; D010573:Pesticide Residues; D010575:Pesticides; C032159:acetonitrile