title: Cross-Neutralization between Human and African Bat Mumps Viruses.
abstract: Recently, a new paramyxovirus closely related to human mumps virus (MuV) was detected in bats. We generated recombinant MuVs carrying either or both of the fusion and hemagglutinin-neuraminidase bat virus glycoproteins. These viruses showed replication kinetics similar to human MuV in cultured cells and were neutralized efficiently by serum from healthy humans.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Katoh
authors.forename: Toru
authors.initials: T
authors.lastname: Kubota
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Ihara
authors.forename: Ken
authors.initials: K
authors.lastname: Maeda
authors.forename: Makoto
authors.initials: M
authors.lastname: Takeda
authors.forename: Minoru
authors.initials: M
authors.lastname: Kidokoro
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood*; D002460:Cell Line; D002685:Chiroptera; D002522:Chlorocebus aethiops; D003412:Cricetulus; D015023:Democratic Republic of the Congo / Q000453:epidemiology; D005260:Female; D015870:Gene Expression; D015707:HN Protein / Q000235:genetics / Q000276:immunology; D058507:Host Specificity; D006801:Humans; D007106:Immune Sera / Q000737:chemistry / Q000494:pharmacology; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009107:Mumps / Q000453:epidemiology / Q000276:immunology* / Q000662:veterinary* / Q000821:virology; D009109:Mumps virus / Q000235:genetics* / Q000254:growth & development / Q000302:isolation & purification; D009500:Neutralization Tests; D016865:Reassortant Viruses / Q000235:genetics / Q000276:immunology*; D014709:Vero Cells; D014760:Viral Fusion Proteins / Q000037:antagonists & inhibitors / Q000235:genetics / Q000276:immunology*
chemical_list: D000914:Antibodies, Viral; D015707:HN Protein; D007106:Immune Sera; D014760:Viral Fusion Proteins
keywords: African bat mumps virus; Chimeric virus; bat virus; mumps virus; neutralization; viruses