title: Ocular response analyser measurements and central corneal thickness in ocular rosacea patients.
abstract: Rosacea is a chronic cutaneous disorder which is known to cause inflammation and increased proteolytic activity on the ocular surface that might lead to corneal biomechanical alterations. The aim of this study is to evaluate the corneal biomechanical properties of ocular rosacea patients and compare the measurements with healthy individuals as measured with Reichert ocular response analyser (ORA). Besides full eye examination [best corrected visual acuity (BCVA), intraocular pressure (IOP) measured with Goldmann applanation tonometry (IOP-G)], central corneal thickness (CCT), and ORA [corneal hysteresis (CH), corneal resistance factor (CRF), corneal compensated IOP (IOPcc), Goldmann correlated IOP (IOPg)] measurements of 30 eyes of 15 ocular rosacea patients (study group) and 30 eyes of 15 healthy individuals (control group) were performed. For comparisons paired t test was used. Mean age of study group was 45.26 ± 11.65 (range 25 and 63) and control group was 45.00 ± 8.91 (range 26 and 58) years (p = 0.865). No significant difference in BCVA, CCT, IOP-G, IOPcc was detected among groups. However, IOPg, CH, and CRF in the study group were significantly lower than in the control group (p = 0.013, p = 0.013, p = 0.009, respectively). IOPg, CH, and CRF parameters of ocular rosacea patients were significantly lower than normal individuals. These differences and their probable clinical reflections that might effect making decisions in conditions such as glaucoma should be investigated in larger number of patients.
authors.affiliation: Department of Ophthalmology, Ege University Faculty of Medicine, Izmir, Turkey. melispalamar@hotmail.com.
authors.forename: Melis
authors.initials: M
authors.lastname: Palamar
authors.affiliation: Department of Ophthalmology, Ege University Faculty of Medicine, Izmir, Turkey.
authors.forename: Cumali
authors.initials: C
authors.lastname: Degirmenci
authors.affiliation: Department of Dermatology, Ege University Faculty of Medicine, Izmir, Turkey.
authors.forename: Ilgen
authors.initials: I
authors.lastname: Ertam
authors.affiliation: Department of Ophthalmology, Ege University Faculty of Medicine, Izmir, Turkey.
authors.forename: Ayse
authors.initials: A
authors.lastname: Yagci
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D016022:Case-Control Studies; D003315:Cornea / Q000473:pathology* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012393:Rosacea / Q000503:physiopathology*; D014065:Tonometry, Ocular; D014792:Visual Acuity / Q000502:physiology
keywords: Corneal hysteresis; Corneal resistance factor; Ocular response analyser; Ocular rosacea