title: Characterization, nanoparticle self-organization, and Monte Carlo simulation of magnetoliposomes.
abstract: In this work we have developed and implement a new approach for the study of magnetoliposomes using Monte Carlo simulations. Our model is based on interaction among nanoparticles considering magnetic dipolar, van der Waals, ionic-steric, and Zeeman interaction potentials. The ionic interaction between nanoparticles and the lipid bilayer is represented by an ionic repulsion electrical surface potential that depends on the nanoparticle-lipid bilayer distance and the concentration of ions in the solution. A direct comparison among transmission electron microscopy, vibrating sample magnetometer, dynamic light scattering, nanoparticle tracking analysis, and experimentally derived static magnetic birefringence and simulation data allow us to validate our implementation. Our simulations suggest that confinement plays an important role in aggregate formation.
authors.affiliation: Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Rua Santa Adelia 166, CEP 09210-170, Santo André, SP, Brazil.
authors.forename: Michele Aparecida
authors.initials: MA
authors.lastname: Salvador
authors.affiliation: Instituto de Física, Universidade Federal de Goiás, CEP 74.690-900, Goiânia, Go, Brazil.
authors.forename: Anderson Silva
authors.initials: AS
authors.lastname: Costa
authors.affiliation: Faculdade de Farmácia, Universidade Federal de Goiás, CEP 74605-220, Goiânia, Go, Brazil.
authors.forename: Marilisa
authors.initials: M
authors.lastname: Gaeti
authors.affiliation: Faculdade de Farmácia, Universidade Federal de Goiás, CEP 74605-220, Goiânia, Go, Brazil.
authors.forename: Livia Palmerston
authors.initials: LP
authors.lastname: Mendes
authors.affiliation: Faculdade de Farmácia, Universidade Federal de Goiás, CEP 74605-220, Goiânia, Go, Brazil.
authors.forename: Eliana Martins
authors.initials: EM
authors.lastname: Lima
authors.affiliation: Instituto de Física, Universidade Federal de Goiás, CEP 74.690-900, Goiânia, Go, Brazil.
authors.forename: Andris Figueiroa
authors.initials: AF
authors.lastname: Bakuzis
authors.affiliation: Centro de Ciências Naturais e Humanas, Universidade Federal do ABC, Rua Santa Adelia 166, CEP 09210-170, Santo André, SP, Brazil.
authors.forename: Ronei
authors.initials: R
authors.lastname: Miotto
mesh_terms: D008051:Lipid Bilayers / Q000737:chemistry; D008081:Liposomes / Q000737:chemistry*; D059346:Magnets / Q000737:chemistry*; D008958:Models, Molecular; D008968:Molecular Conformation; D009010:Monte Carlo Method; D053758:Nanoparticles / Q000737:chemistry*
chemical_list: D008051:Lipid Bilayers; D008081:Liposomes