title: Non-directed, carbonate-mediated C-H activation and aerobic C-H oxygenation with Cp*Ir catalysts.
abstract: The effect of oxidatively stable L- and X-type additives on the activity of Cp*Ir catalyst precursors in the C-H activation of arenes has been studied. Turnover numbers for C-H activation of up to 65 can thus be achieved, as determined by H/D exchange in MeOH-D4. In particular, carbonate additives are found to enhance the C-H activation reactivity of Cp*Ir(H2O)3(OTf)2 () more significantly than L-type ligands investigated in this study. Based on these studies, Cp*Ir/carbonate systems are developed that catalyze the aerobic Csp(3)-H oxygenation of alkyl arenes, employing air as oxidant.
authors.affiliation: Department of Chemistry & Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. mhemmert@wpi.edu and Chemistry Department, Worcester State University, 486 Chandler Street, Worcester, MA 01602, USA.
authors.forename: M E
authors.initials: ME
authors.lastname: Kerr
authors.affiliation: Department of Chemistry & Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. mhemmert@wpi.edu.
authors.forename: I
authors.initials: I
authors.lastname: Ahmed
authors.affiliation: Department of Chemistry & Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. mhemmert@wpi.edu.
authors.forename: A
authors.initials: A
authors.lastname: Gunay
authors.affiliation: Department of Chemistry & Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. mhemmert@wpi.edu.
authors.forename: N J
authors.initials: NJ
authors.lastname: Venditto
authors.affiliation: Department of Chemistry & Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. mhemmert@wpi.edu.
authors.forename: F
authors.initials: F
authors.lastname: Zhu
authors.affiliation: Department of Chemistry, North Carolina State University, 2620 Yarbrough Drive, Raleigh, NC 27695-8204, USA.
authors.forename: E A
authors.initials: EA
authors.lastname: Ison
authors.affiliation: Department of Chemistry & Biochemistry, Worcester Polytechnic Institute, 100 Institute Road, Worcester, MA 01609, USA. mhemmert@wpi.edu.
authors.forename: M H
authors.initials: MH
authors.lastname: Emmert