title: Characterization of an IncA/C Multidrug Resistance Plasmid in Vibrio alginolyticus.
abstract: Cephalosporin-resistant Vibrio alginolyticus was first isolated from food products, with β-lactamases encoded by blaPER-1, blaVEB-1, and blaCMY-2 being the major mechanisms mediating their cephalosporin resistance. The complete sequence of a multidrug resistance plasmid, pVAS3-1, harboring the blaCMY-2 and qnrVC4 genes was decoded in this study. Its backbone exhibited genetic homology to known IncA/C plasmids recoverable from members of the family Enterobacteriaceae, suggesting its possible origin in Enterobacteriaceae.
authors.affiliation: College of Animal Science and Technology, Nanjing Agriculture University, Nanjing, People's Republic of China Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China.
authors.forename: Lianwei
authors.initials: L
authors.lastname: Ye
authors.affiliation: Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors.forename: Ruichao
authors.initials: R
authors.lastname: Li
authors.affiliation: Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors.forename: Dachuan
authors.initials: D
authors.lastname: Lin
authors.affiliation: Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors.forename: Yuanjie
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Wuhan Institute of Biotechnology, Wuhan, China.
authors.forename: Aisi
authors.initials: A
authors.lastname: Fu
authors.affiliation: Wuhan Institute of Biotechnology, Wuhan, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Ding
authors.affiliation: Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
authors.forename: Edward Wai Chi
authors.initials: EW
authors.lastname: Chan
authors.affiliation: College of Animal Science and Technology, Nanjing Agriculture University, Nanjing, People's Republic of China sheng.chen@polyu.edu.hk yaowen67jp@njau.edu.cn.
authors.forename: Wen
authors.initials: W
authors.lastname: Yao
authors.affiliation: Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Centre, The Hong Kong PolyU Shenzhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong sheng.chen@polyu.edu.hk yaowen67jp@njau.edu.cn.
authors.forename: Sheng
authors.initials: S
authors.lastname: Chen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics; D010957:Plasmids / Q000235:genetics; D044149:Vibrio alginolyticus / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases