title: [Benign struma ovarii: Report of 7 cases and review of the literature].
abstract: OBJECTIVE
  Struma ovarii is a monodermal teratoma composed of thyroid tissue, representing 0.85 to 1.3% of ovarian tumors. The objective of the present study is to report a continuous series of struma ovarii, with a comprehensive analysis of the literature.
  
  
  METHODS
  A retrospective study in the gynecological surgery department of Hôpital Femme-Mère-Enfant (Hospices Civils de Lyon, Lyon, France) assessed a continuous series of struma ovarii from the Lyon East Pathology Center database. Clinical and biological, imaging and pathological aspects were analyzed and the various forms of treatment described.
  
  
  RESULTS
  We identified 7 patients with struma ovarii from March 2008 to April 2015. Mean patient age was 49.7 years (28-70years). Three patients had a history of thyroid disease. CA-125 was elevated (51IU/mL) in only 1 patient. MRI and ultrasound imaging did not enable diagnosis of struma ovarii, which depended on pathologic examination. Conservative surgery for cystectomy or oophorectomy was performed for patients wishing to become pregnant (71%); nonconservative hysterectomy was performed in postmenopausal women (29%).
  
  
  CONCLUSIONS
  Struma ovarii is a rare, often asymptomatic condition in which diagnosis is difficult. Few series are described in the literature. Here we propose a management model for struma ovarii. Revision surgery and adjuvant therapy is indicated in case of malignant struma ovarii.
authors.affiliation: Service de chirurgie gynécologique, université Claude Bernard-Lyon 1, hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69677 Lyon-Bron, France. Electronic address: gery.lamblin@chu-lyon.fr.
authors.forename: G
authors.initials: G
authors.lastname: Lamblin
authors.affiliation: Service de chirurgie gynécologique, université Claude Bernard-Lyon 1, hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69677 Lyon-Bron, France.
authors.forename: C
authors.initials: C
authors.lastname: Gallice
authors.affiliation: Service de médecine nucléaire, groupement hospitalier Est, 59, boulevard Pinel, 69677 Lyon-Bron, France.
authors.forename: C
authors.initials: C
authors.lastname: Bournaud
authors.affiliation: Service de pathologie Est (CPE), groupement hospitalier Est, 59, boulevard Pinel, 69677 Lyon-Bron, France.
authors.forename: B
authors.initials: B
authors.lastname: Nadaud
authors.affiliation: Service de chirurgie gynécologique, université Claude Bernard-Lyon 1, hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69677 Lyon-Bron, France.
authors.forename: K
authors.initials: K
authors.lastname: Lebail-Carval
authors.affiliation: Service de chirurgie gynécologique, université Claude Bernard-Lyon 1, hôpital Femme-Mère-Enfant, 59, boulevard Pinel, 69677 Lyon-Bron, France.
authors.forename: G
authors.initials: G
authors.lastname: Chene
mesh_terms: D000328:Adult; D000368:Aged; D015653:Cystectomy; D005260:Female; D005602:France; D006801:Humans; D007044:Hysterectomy; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D010051:Ovarian Neoplasms / Q000473:pathology* / Q000601:surgery*; D010052:Ovariectomy; D012189:Retrospective Studies; D013330:Struma Ovarii / Q000473:pathology* / Q000601:surgery*; D013959:Thyroid Diseases / Q000150:complications; D014463:Ultrasonography
keywords: Goitre ovarien; Kyste ovaire; Ovarian cyst; Struma ovarii; Thyroid; Thyroïde