title: Long term follow-up of a tobacco prevention and cessation program in cystic fibrosis patients.
abstract: This study evaluates the impact over time of a telephone-based intervention in tobacco cessation and prevention targeting patients with cystic fibrosis (CF) in the Mediterranean region of Murcia, Spain. We conducted an experimental prospective study with a cohort of CF patients using an integrative smoking cessation programme, between 2008 and 2013. The target population included family members and patients from the Regional CF unit. The study included an initial tobacco exposure questionnaire, measurement of lung function, urinary cotinine levels, anthropomorphic measures and the administered intervention at specific time intervals. Of the 88 patients tracked through follow-up, active smoking rates were reduced from 10.23% to 4.55% (p = 0.06). Environmental tobacco exposure was reduced in non-smoker patients from 62.03% to 36.90% (p &lt; 0.01) during the five year follow-up. Significant reductions in the gradient of household tobacco smoke exposure were also observed with a decrease of 12.60%, from 31.65% (n = 25/79) to 19.05% (n = 16/84) in 2013 (p = &lt;0.01). Cotinine was significantly correlated with both active and passive exposure (p&lt;0.01) with a significant reduction of cotinine levels from 63.13 (28.58-97.69) to 20.56 (0.86-40.27) ng/ml (p&lt;0.01). The intervention to significantly increase the likelihood of family quitting (smoke-free home) was 1.26 (1.05-1.54). Telephone based interventions for tobacco cessation and prevention is a useful tool when applied over time. Trained intervention professionals in this area are needed in the environmental health approach for the treatment of CF.
authors.affiliation: Hospital Clínico Universitario Virgen de la Arrixaca. Murcia, España. ortega@pehsu.org.
authors.forename: Juan Antonio
authors.initials: JA
authors.lastname: Ortega-García
authors.forename: Joseph E
authors.initials: JE
authors.lastname: Perales
authors.forename: Alberto
authors.initials: A
authors.lastname: Cárceles-Álvarez
authors.forename: Miguel Felipe
authors.initials: MF
authors.lastname: Sánchez-Sauco
authors.forename: Seiichi
authors.initials: S
authors.lastname: Villalona
authors.forename: Pedro
authors.initials: P
authors.lastname: Mondejar-López
authors.forename: María Dolores
authors.initials: MD
authors.lastname: Pastor-Vivero
authors.forename: Pilar
authors.initials: P
authors.lastname: Mira Escolano
authors.forename: Diana Carolina
authors.initials: DC
authors.lastname: James-Vega
authors.forename: Manuel
authors.initials: M
authors.lastname: Sánchez-Solís
mesh_terms: D000328:Adult; D003550:Cystic Fibrosis; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D011446:Prospective Studies; D016540:Smoking Cessation; D013030:Spain; D013997:Time Factors; D014028:Tobacco Smoke Pollution / Q000517:prevention & control*; D064424:Tobacco Use / Q000517:prevention & control*; D055815:Young Adult
chemical_list: D014028:Tobacco Smoke Pollution