title: Palladium-Catalyzed Enantioselective Intermolecular Carboetherification of Dihydrofurans.
abstract: A novel enantioselective Pd-catalyzed intermolecular carboetherification of dihydrofurans is reported. The in situ generation of chiral bis-phosphine mono-oxide ligands is crucial, and a general catalytic system has been identified based on this approach. It provides access to a variety of fused tetrahydrofurobenzofurans in consistently high yield and enantiomeric excess.
authors.affiliation: Department of Organic Chemistry, University of Geneva , 30 quai Ernest Ansermet, 1211 Geneva, Switzerland.
authors.forename: Gustavo M
authors.initials: GM
authors.lastname: Borrajo-Calleja
authors.affiliation: Department of Organic Chemistry, University of Geneva , 30 quai Ernest Ansermet, 1211 Geneva, Switzerland.
authors.forename: Vincent
authors.initials: V
authors.lastname: Bizet
authors.affiliation: Department of Organic Chemistry, University of Geneva , 30 quai Ernest Ansermet, 1211 Geneva, Switzerland.
authors.forename: Clément
authors.initials: C
authors.lastname: Mazet