title: [Zika virus - ancient virus gets new life in a new ecosystem. Microcephaly and Guillain-Barre syndrome are possible consequences when there is no background herd immunity in the population].
abstract: Zika virus is a mosquito-borne flavivirus transmitted by Aedes mosquitos. The virus was discovered in 1947 in the Zika forest in Uganda. Symptomatic disease is usually mild and is characterized by maculopapular rash, headache, fever, arthralgia and conjunctivitis. Fatalities are rare. There is neither vaccine nor curative treatment available. In May 2015, the first observation of local virus transmission was reported from Brazil. During the expanding outbreak in the Americas, Zika virus infection has been associated with microcephaly in newborn and fetal losses in women infected with Zika virus during pregnancy. The main reason for the current epidemic in the Americas is the introduction of an Old World virus into a new ecosystem, with no background herd immunity in the population. It is likely that the spread of Zika virus will continue, affecting all countries in the Americas except for Chile and Canada.
authors.affiliation: Institutionen för medicinska vetenskaper, infektionssjukdomar - Uppsala universitet Uppsala, Sweden Institutionen för medicinska vetenskaper - Uppsala universitet Uppsala, Sweden.
authors.forename: Björn
authors.initials: B
authors.lastname: Olsen
authors.affiliation: Uppsala universitetet Institutionen for medicinsk biokemi och mikrobiologi - Uppsala, Sweden Uppsala universitetet Institutionen for medicinsk biokemi och mikrobiologi - Uppsala, Sweden.
authors.forename: Åke
authors.initials: Å
authors.lastname: Lundkvist
mesh_terms: D021821:Communicable Diseases, Emerging; D005260:Female; D020275:Guillain-Barre Syndrome / Q000821:virology; D006801:Humans; D032521:Immunity, Herd; D008831:Microcephaly / Q000821:virology; D011247:Pregnancy; D000071244:Zika Virus / Q000276:immunology*; D000071243:Zika Virus Infection / Q000150:complications / Q000276:immunology / Q000635:transmission