title: Substance Use Patterns of HIV-Infected Russian Women with and Without Hepatitis C Virus Co-infection.
abstract: Individuals with HIV and hepatitis C virus (HCV) co-infection may experience substance use related health complications. This study characterized substance use patterns between HIV/HCV co-infected and HIV mono-infected Russian women. HIV-infected women (N = 247; M age = 30.0) in St. Petersburg, Russia, completed a survey assessing substance use, problematic substance use, and the co-occurrence of substance use and sexual behaviors. Covariate adjusted logistic and linear regression analyses indicated that HIV/HCV co-infected participants (57.1 %) reported more lifetime drug use (e.g., heroin: AOR: 13.2, 95 % CI 4.9, 35.3, p < .001), problem drinking (β = 1.2, p = .05), substance use problems (β = 1.3, p = .009), and increased likelihood of past injection drug use (AOR: 26.4, 95 % CI 8.5, 81.9, p < .001) relative to HIV mono-infected individuals. HIV/HCV co-infection was prevalent and associated with increased substance use and problematic drug use. Findings highlight the need for ongoing substance use and HIV/HCV risk behavior assessment and treatment among HIV/HCV co-infected Russian women.
authors.affiliation: Addiction Sciences Division, Department of Psychiatry & Behavioral Neuroscience, University of Cincinnati College of Medicine, 3131 Harvey Avenue, Suite 104, Cincinnati, OH, 45229, USA. jennifer.brown2@uc.edu.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Brown
authors.affiliation: Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.|Centers for AIDS Research, Emory University, Atlanta, GA, USA.|Department of Pediatrics, Division of Infectious Diseases, Epidemiology and Immunology, Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Ralph J
authors.initials: RJ
authors.lastname: DiClemente
authors.affiliation: Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.|Centers for AIDS Research, Emory University, Atlanta, GA, USA.
authors.forename: Jessica M
authors.initials: JM
authors.lastname: Sales
authors.affiliation: Department of Behavioral Sciences and Health Education, Rollins School of Public Health, Emory University, Atlanta, GA, USA.
authors.forename: Eve S
authors.initials: ES
authors.lastname: Rose
authors.affiliation: St. Petersburg AIDS Center, St. Petersburg, Russia.
authors.forename: Polina
authors.initials: P
authors.lastname: Safonova
authors.affiliation: Stellit, St. Petersburg, Russia.
authors.forename: Olga S
authors.initials: OS
authors.lastname: Levina
authors.affiliation: North-West Regional Center for Control and Prevention of AIDS, St. Petersburg, Russia.
authors.forename: Nikolay
authors.initials: N
authors.lastname: Belyakov
authors.affiliation: St. Petersburg AIDS Center, St. Petersburg, Russia.
authors.forename: Vadim V
authors.initials: VV
authors.lastname: Rassokhin
mesh_terms: D000328:Adult; D060085:Coinfection / Q000150:complications / Q000453:epidemiology*; D005260:Female; D015658:HIV Infections / Q000188:drug therapy / Q000453:epidemiology*; D016174:Hepacivirus; D006526:Hepatitis C / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D015995:Prevalence; D012426:Russia / Q000453:epidemiology; D012725:Sexual Behavior; D015819:Substance Abuse, Intravenous / Q000150:complications / Q000453:epidemiology*; D019966:Substance-Related Disorders / Q000150:complications / Q000453:epidemiology*; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: HCV; HIV-infected; Problematic substance use; Russian women; Substance use