title: Infantile-onset glaucoma and anterior megalophthalmos in osteogenesis imperfecta.
abstract: Osteogenesis imperfecta (OI) is an inherited condition in which defects in type 1 collagen cause abnormalities in many tissues and organs, including bone, teeth, heart valves, and eyes. We describe a 6-month-old boy with OI who presented with anterior megalophthalmos of the right eye and infantile-onset glaucoma of the left eye. To our knowledge, this is the first reported case of these types of congenital eye anomalies in an infant with OI.
authors.affiliation: Department of Ophthalmology and Visual Sciences, University of Michigan, Ann Arbor. Electronic address: brendabo@med.umich.edu.
authors.forename: Brenda L
authors.initials: BL
authors.lastname: Bohnsack
mesh_terms: D058452:Axial Length, Eye / Q000473:pathology; D015715:Corneal Edema / Q000175:diagnosis / Q000209:etiology; D015785:Eye Diseases, Hereditary / Q000175:diagnosis / Q000209:etiology*; D040181:Genetic Diseases, X-Linked / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D006871:Hydrophthalmos / Q000175:diagnosis / Q000209:etiology* / Q000601:surgery; D007223:Infant; D007429:Intraocular Pressure; D008297:Male; D010013:Osteogenesis Imperfecta / Q000150:complications*; D010375:Pedigree; D014130:Trabeculectomy; D014792:Visual Acuity