title: Serum irisin concentrations were increased after transient continuous subcutaneous insulin infusion in type 2 diabetes mellitus patients.
abstract: Irisin, identified as a novel myokine, plays an important role in improving metabolic disorders, including type 2 diabetes mellitus (T2DM). In this interventional study, we investigated the alteration of serum irisin levels in T2DM subjects after transient continuous subcutaneous insulin infusion (CSII) treatment.
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China.
authors.forename: Sharvan
authors.initials: S
authors.lastname: Rampersad
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China.
authors.forename: Xingchun
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China. Electronic address: chengxiaoyun0210@163.com.
authors.forename: Xiaoyun
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Department of Endocrinology and Metabolism, Shanghai Tenth People's Hospital, Tongji University, School of Medicine, Shanghai 200072, China.
authors.forename: Shen
authors.initials: S
authors.lastname: Qu
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000188:drug therapy; D004334:Drug Administration Schedule; D005260:Female; D005353:Fibronectins / Q000097:blood*; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage*; D055104:Infusions, Subcutaneous; D007328:Insulin / Q000008:administration & dosage*; D008297:Male; D008875:Middle Aged
chemical_list: D015415:Biomarkers; C577593:FNDC5 protein, human; D005353:Fibronectins; D007004:Hypoglycemic Agents; D007328:Insulin
keywords: CSII; HbA1c; Irisin; Lipid profiles; T2DM