title: A patient centred approach to basal insulin choice for the management of type 2 diabetes mellitus.
abstract: Basal insulins are first line injectable therapy by all international guidelines. Basal insulins can be used alone, in combination with metformin, dual or triple oral therapy, glucagon-like peptide receptor agonists, or prandial insulin. However, all basal insulins are not similar. This article proposes objective parameters, and suggests a simple checklist, using history, physical examination, and investigations, to help choose the appropriate preparation, viz degludec, detemir, glargine or NPH insulin, for persons requiring basal insulin.
authors.affiliation: Department of Endocrinology, 1Bharti Hospital, Karnal, 2All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kalra
authors.affiliation: Department of Endocrinology, 1Bharti Hospital, Karnal, 2All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Yashdeep
authors.initials: Y
authors.lastname: Gupta
mesh_terms: D057189:Checklist; D000066491:Clinical Decision-Making; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D004359:Drug Therapy, Combination; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D000069057:Insulin Detemir / Q000627:therapeutic use; D000069036:Insulin Glargine / Q000627:therapeutic use; D007336:Insulin, Isophane / Q000627:therapeutic use; D049528:Insulin, Long-Acting / Q000627:therapeutic use; D008687:Metformin / Q000627:therapeutic use; D018802:Patient-Centered Care
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin; D049528:Insulin, Long-Acting; D000069036:Insulin Glargine; D000069057:Insulin Detemir; D007336:Insulin, Isophane; C571886:insulin degludec; D008687:Metformin
keywords: Degludec, detemir, glargine, insulin, NPH, U300 glargine.