title: Putting the brain in Jeopardy: a novel comprehensive and expressive language task?
abstract: OBJECTIVE
  To develop and test a novel fMRI compatible comprehensive and expressive language task that reliably and predictably activates both Wernicke's and Broca's cortical brain regions, respectively, and has utility for the determination of hemispheric language dominance.
  
  
  METHODS
  Ten healthy men (seven) and women (three) were administered a task based on the television game Jeopardy that was adapted for fMRI presentation. The task was programmed using E-PRIME software and designed to run as an event-related experiment. The study was conducted on 3 T MRI Phillips Intera scanner, and data was anlysed using Brain Voyager QX. All subjects provided written informed consent.
  
  
  RESULTS
  The Jeopardy task produced robust left hemisphere activation in regions corresponding to Wernicke's and Broca's areas.
  
  
  CONCLUSIONS
  This novel fMRI compatible task (Jeopardy) reliably maps both Broca's and Wernicke's areas with robust hemispheric lateralization. It is potentially useful in language localization studies as it offers advantages over conventional procedures and other fMRI tasks by virtue of being non-invasive and mapping both language areas in one experiment.
authors.affiliation: 1Department of Circulation and Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Erik Magnus
authors.initials: EM
authors.lastname: Berntsen
authors.affiliation: 1Department of Circulation and Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Inge-Andre
authors.initials: IA
authors.lastname: Rasmussen
authors.affiliation: 1Department of Circulation and Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Petter
authors.initials: P
authors.lastname: Samuelsen
authors.affiliation: 1Department of Circulation and Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Jian
authors.initials: J
authors.lastname: Xu
authors.affiliation: 1Department of Circulation and Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: Olav
authors.initials: O
authors.lastname: Haraldseth
authors.affiliation: 2School of Psychiatry, University of New South Wales, Sydney, Australia.
authors.forename: Jim
authors.initials: J
authors.lastname: Lagopoulos
authors.affiliation: 2School of Psychiatry, University of New South Wales, Sydney, Australia.
authors.forename: Gin S
authors.initials: GS
authors.lastname: Malhi