title: [Differences between MDRD-4 and CG in the prevalence of renal failure and its associated variables in type2 diabetic patients].
abstract: OBJECTIVE
  To estimate the prevalence of occult renal failure (RF) in DM2, by comparing two formulas for estimating glomerular filtration rate (GFR): Modification of Diet in Renal Disease 4 (MDRD-4) and Cockcroft-Gault (CG), as well as their associated clinical variables.
  
  
  METHODS
  Multicentre analytical cross-sectional.
  
  
  METHODS
  Two basic Primary Care areas in Terres de l'Ebre, in North-Eastern Spain.
  
  
  METHODS
  A total of 493 DM2 patients with age >18years with an assigned doctor in the areas studied. There was a loss of 9 and 11 cases in each formula due to lack of variables necessary for the GFR.
  
  
  METHODS
  Estimated GFR using the two formulas, plasma creatinine values, classification of patients with established RF, occult RF and without RF, and possible clinical-pathological variables associated with RF.
  
  
  RESULTS
  Of the total, 45.2% were men, the mean age was 70.4 years, and mean time since onset of diabetes of 7.5 years. The prevalence of occult RF with MDRD-4 was 18%, and 22.6% with CG. The cases detected by GC and not by MDRD-4 were higher, and with lower weight. In both formulas, occult RF patients had more chronic diseases, hypertension, and cardiovascular events (CV) than those without RF. Risk factors associated with occult RF were female, increasing age, and LDL cholesterol.
  
  
  CONCLUSIONS
  The prevalence of occult RF was 20% in DM2, independently of the formula. A poorer control of cardiovascular risk factors was observed, which makes them a group at higher risk of suffering a CV event.
authors.affiliation: ABS Tortosa-Oest, Institut Català de la Salut (ICS), Tortosa, Tarragona, España; ABS Tortosa-Est, Institut Català de la Salut (ICS), Tortosa, Tarragona, España.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Dalmau Llorca
authors.affiliation: ABS Flix, Institut Català de la Salut (ICS), Flix, Tarragona, España.
authors.forename: Míriam
authors.initials: M
authors.lastname: Boira Costa
authors.affiliation: Institut Universitari d'Investigació en Atenció Primària (IDIAP) Jordi Gol, UAB, Barcelona, España; Unitat de Suport a la Recerca Terres de l'Ebre IISPV, URV, Tortosa, Tarragona, España.
authors.forename: Carlos
authors.initials: C
authors.lastname: López Pablo
authors.affiliation: ABS Tortosa-Oest, Institut Català de la Salut (ICS), Tortosa, Tarragona, España.
authors.forename: Josep Maria
authors.initials: JM
authors.lastname: Pepió Vilaubí
authors.affiliation: ABS Tortosa-Oest, Institut Català de la Salut (ICS), Tortosa, Tarragona, España.
authors.forename: Carina
authors.initials: C
authors.lastname: Aguilar Martin
authors.affiliation: ABS Ulldecona-la Sénia, Institut Català de la Salut (ICS), Ulldecona, Tarragona, España. Electronic address: eforcadellg.ebre.ics@gencat.cat.
authors.forename: Emma
authors.initials: E
authors.lastname: Forcadell Drago
mesh_terms: D000368:Aged; D002318:Cardiovascular Diseases / Q000209:etiology*; D003404:Creatinine; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D008297:Male; D015995:Prevalence; D051437:Renal Insufficiency / Q000209:etiology*; D012307:Risk Factors; D013030:Spain
chemical_list: D003404:Creatinine
keywords: Atención primaria; Creatinina; Creatinine; Diabetes mellitus tipo 2; Diabetes mellitus type 2; Filtrado glomerular; Formula; Fórmula; Glomerular filtrate; Insuficiencia renal; Primary care; Renal failure