title: Relationship between thigh intermuscular adipose tissue accumulation and number of metabolic syndrome risk factors in middle-aged and older Japanese adults.
abstract: To evaluate the association between thigh intermuscular adipose tissue accumulation and number of metabolic syndrome risk factors in middle-aged and older Japanese adults.
  
  
  
  Thigh muscle cross-sectional area, subcutaneous adipose tissue, thigh intermuscular adipose tissue, abdominal subcutaneous adipose tissue, and visceral adipose tissue were measured in 166 middle-aged and older (mean age, 69years) Japanese adults using magnetic resonance imaging. Daily physical activity was calculated using pedometers, and energy intake per day was evaluated using 3-day dietary records. Multiple linear regression analysis was used to assess the association between intermuscular adipose tissue and the number of metabolic syndrome risk factors.
  
  
  
  Multiple regression analysis indicated that intermuscular adipose tissue was significantly associated with the number of metabolic syndrome risk factors, after adjusting for age, sex, body mass index, daily physical activity, energy intake, thigh muscle cross-sectional area, and visceral adipose tissue (p<0.05).
  
  
  
  Thigh intermuscular adipose tissue accumulation was significantly associated with the number of metabolic syndrome risk factors in middle-aged and older Japanese adults, independent of age, sex, body mass index, daily physical activity, energy intake, thigh muscle cross-sectional area, and visceral adipose tissue.
authors.affiliation: Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8577, Japan. Electronic address: bangeunji000@gmail.com.
authors.forename: Eunji
authors.initials: E
authors.lastname: Bang
authors.affiliation: Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8577, Japan. Electronic address: tanabe.kai.gm@u.tsukuba.ac.jp.
authors.forename: Kai
authors.initials: K
authors.lastname: Tanabe
authors.affiliation: Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8577, Japan. Electronic address: yokoyama.noriko.ge@u.tsukuba.ac.jp.
authors.forename: Noriko
authors.initials: N
authors.lastname: Yokoyama
authors.affiliation: Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8577, Japan. Electronic address: s.chijiki@gmail.com.
authors.forename: Shoko
authors.initials: S
authors.lastname: Chijiki
authors.affiliation: Department of Sports Medicine, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba City, Ibaraki 305-8577, Japan. Electronic address: kuno@taiiku.tsukuba.ac.jp.
authors.forename: Shinya
authors.initials: S
authors.lastname: Kuno
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000473:pathology*; D000368:Aged; D000375:Aging / Q000473:pathology* / Q000502:physiology; D000886:Anthropometry / Q000379:methods; D001823:Body Composition / Q000502:physiology; D002149:Energy Intake / Q000502:physiology; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D024821:Metabolic Syndrome / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology; D008875:Middle Aged; D012307:Risk Factors; D013848:Thigh / Q000000981:diagnostic imaging / Q000473:pathology*
keywords: Intermuscular adipose tissue; Japanese adults; Metabolic syndrome; Skeletal muscle mass