title: Beware of manipulations on the genome: epigenetic destabilization through (foreign) DNA insertions.
authors.affiliation: Institute for Virology, Friedrich-Alexander-University Erlangen-Nürnberg, D-91054 Erlangen, Germany; and Institute of Genetics, University of Cologne, D-50674 Cologne, Germany.
authors.forename: Walter
authors.initials: W
authors.lastname: Doerfler
mesh_terms: D000818:Animals; D030801:Animals, Genetically Modified; D057005:Bioengineering / Q000379:methods / Q000639:trends; D004251:DNA Transposable Elements / Q000502:physiology*; D044127:Epigenesis, Genetic / Q000502:physiology*; D016678:Genome / Q000235:genetics*; D042822:Genomic Instability; D006801:Humans; D051379:Mice; D016254:Mutagenesis, Insertional / Q000235:genetics / Q000379:methods / Q000502:physiology*
chemical_list: D004251:DNA Transposable Elements
keywords: DNA methylation; biology and the concepts of dark energy and dark matter; epigenetic consequences and evolution; epigenetic consequences of foreign DNA insertions; epigenetic mechanisms of oncogenesis; epigenetic sequelae of genome manipulations; food ingested DNA; foreign DNA integration into mammalian genomes; hypothesis on DNA as recipient for cosmic emissions; transcriptional profiles