title: Zinc oxide-copper oxide nanoplates composite as coating for solid phase microextraction combined with high performance liquid chromatography-UV detection for trace analysis of chlorophenols in water and tomato juice samples.
abstract: In the present research, the ZnO-CuO nanoplate composite (ZCNC), solid-phase microextraction (SPME) fiber coating, was prepared and its extraction capability for certain chlorophenols (CPs) was studied through directly sampling the typical CPs mixed standard solution of 4-chlorophenol, 2,3-dichlorophenol, 2,5-dichlorophenol, and 2,4,6-trichlorophenol with high performance liquid chromatography. ZCNC thickness was in the range of 50-65 nm. The effective variables on ZCNC-SPME extraction efficiency were extraction time, salt percentage, and desorption time. Accordingly, a multivariate strategy was applied based on an experimental design by using central composite design for optimizing the significant factors affecting the extraction efficiency. The detection limit and relative standard deviation (RSD) (n = 6), that include repeatability and reproducibility as the target analytes, were in the range of 0.5-5 ng ml(-1) and 5.1-14 % of standard solutions at 50 ng ml(-1) concentration of CPs, respectively. The developed technique is believed to be successfully applicable to preconcentration and determination of target analytes in environmental water and tomato juice samples. Graphical Abstract Application of zinc oxide-copper oxide nanoplates composite for extraction of chlorophenols in water and tomato juice samples and optimizing condition by experimental design method.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Qom, Qom, 3716146611, Iran. r_alizadeh2005@yahoo.com.
authors.forename: Reza
authors.initials: R
authors.lastname: Alizadeh
authors.affiliation: Department of Chemistry, Faculty of Science, Islamic Azad University, Kerman, Iran.
authors.forename: Parvin Khodaei
authors.initials: PK
authors.lastname: Kashkoei
authors.affiliation: Department of Chemistry, Faculty of Science, Islamic Azad University, Kerman, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Kazemipour
mesh_terms: D001628:Beverages / Q000032:analysis*; D002733:Chlorophenols / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D003300:Copper / Q000737:chemistry*; D057230:Limit of Detection; D018551:Solanum lycopersicum; D049329:Nanostructures; D052617:Solid Phase Microextraction / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet / Q000379:methods*; D014867:Water / Q000737:chemistry; D015034:Zinc Oxide / Q000737:chemistry*
chemical_list: D002733:Chlorophenols; D014867:Water; D003300:Copper; D015034:Zinc Oxide; C030973:cupric oxide
keywords: Chemometric design; Chlorophenols; High performance liquid chromatography; Solid phase microextraction; ZnO-CuO nanoplate