title: [Promoting development of new traditional Chinese medicine by combination disease-syndrome and multi-objective optimization research in prevention and treatment of cardiovascular disease].
abstract: Differences in theories, application forms and evaluation standards about curative effect between traditional Chinese medicine and modern medicine lead to not only question safty and effectiveness but also hinder development and internationalization of traditional Chinese medicine. Combination of common problems in traditional Chinese new drug registration with experiences in research on traditional Chinese new drugs of prevention and treatment of coronary heart disease elucidate application value about theory of disease-syndrome combination and multi-objective optimization in several ways such as the indications positioning, preparation process optimization, preclinical efficacy evaluating and clinical assessmenting of efficacy and analysis development prospect.
authors.forename: Jie
authors.initials: J
authors.lastname: Wang
authors.forename: Li-li
authors.initials: LL
authors.lastname: Guo
mesh_terms: D000818:Animals; D035843:Biomedical Research; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D004195:Disease Models, Animal; D055808:Drug Discovery; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage*; D006801:Humans
chemical_list: D004365:Drugs, Chinese Herbal