title: Controlled uptake and release of imatinib from ultrasound nanoparticles Cu3(BTC)2 metal-organic framework in comparison with bulk structure.
abstract: The porosity of metal-organic frameworks (MOFs) is an important point concerning the possible use of such functional materials for different purposes. In this work, we study uptake and release properties of imatinib (IM) from nano Cu(II)-MOF in comparison with bulk Cu(II)-MOF. To explore the absorption ability of the Cu(II)-MOF to IM, fresh sample of Cu3(BTC)2 was immersed in an aqueous solution of IM and were monitored in real time with UV/vis spectroscopy. Results show that the adsorbed quantity of IM over nano Cu3(BTC)2 (I) is much higher than those over a bulk Cu3(BTC)2 (II).
authors.affiliation: Faculty of Chemistry, Razi University, 67194 Kermanshah, Islamic Republic of Iran. Electronic address: ar.abbasi@razi.ac.ir.
authors.forename: Amir Reza
authors.initials: AR
authors.lastname: Abbasi
authors.affiliation: Faculty of Chemistry, Razi University, 67194 Kermanshah, Islamic Republic of Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Rizvandi
authors.affiliation: Department of Chemistry, Khorramabad Branch, Islamic Azad University, Khorramabad, Iran.
authors.forename: Azadeh
authors.initials: A
authors.lastname: Azadbakht
authors.affiliation: Organic and Nano Group (ONG), Department of Chemistry, University of Maragheh, P.O. Box 55181-83111, Maragheh, Islamic Republic of Iran.
authors.forename: Sadegh
authors.initials: S
authors.lastname: Rostamnia
keywords: Imatinib; Metal–organic frameworks; Nanoparticles; Ultrasound