title: Outbreak of adenovirus type 55 infection in Israel.
abstract: BACKGROUND
  Different types of adenoviruses are associated with diverse diseases and with varied disease severity. Adenovirus 55 could be associated with severe respiratory infections.
  
  
  OBJECTIVE
  Here, we report on an adenovirus 55 outbreak in two psychiatric institutions in Israel. The objective of this study was to investigate the adenovirus 55 outbreak.
  
  
  METHODS
  We studied the clinical parameters of the patients and sequencing analysis of certain parts of the virus gene was performed.
  
  
  RESULTS
  We identified the first patient who developed symptoms (the index case) and we showed that while both patients and staff members of the institutions were infected, the disease in the psychiatric patients was more severe. We attributed these differences to their mental and underlying health conditions.
  
  
  CONCLUSIONS
  It is important to monitor for adenovirus infection in the community, especially in mental health institutions to allow appropriate medical care.
authors.affiliation: Tel Aviv District Health Office, Ministry of Health, Tel Aviv, Israel.
authors.forename: Matanelle
authors.initials: M
authors.lastname: Salama
authors.affiliation: Tel Aviv District Health Office, Ministry of Health, Tel Aviv, Israel.
authors.forename: Ziva
authors.initials: Z
authors.lastname: Amitai
authors.affiliation: Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors.forename: Nutman
authors.initials: N
authors.lastname: Amir
authors.affiliation: Infectious Diseases Unit, Wolfson Medical Center, Holon, Israel.
authors.forename: Tamar
authors.initials: T
authors.lastname: Gottesman-Yekutieli
authors.affiliation: Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: Hilda
authors.initials: H
authors.lastname: Sherbany
authors.affiliation: Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: Yaron
authors.initials: Y
authors.lastname: Drori
authors.affiliation: Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel; Department of Epidemiology and Preventive Medicine, School of Public Health, Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Ella
authors.initials: E
authors.lastname: Mendelson
authors.affiliation: Division of Epidemiology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Carmeli
authors.affiliation: Central Virology Laboratory, Ministry of Health, Chaim Sheba Medical Center, Ramat-Gan, Israel. Electronic address: michalman@sheba.health.gov.il.
authors.forename: Michal
authors.initials: M
authors.lastname: Mandelboim
mesh_terms: D000257:Adenoviridae Infections / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D000260:Adenoviruses, Human / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D003428:Cross Infection / Q000453:epidemiology / Q000473:pathology / Q000821:virology; D004279:DNA, Viral / Q000737:chemistry / Q000235:genetics; D004196:Disease Outbreaks; D005260:Female; D005838:Genotype; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D017422:Sequence Analysis, DNA
chemical_list: D004279:DNA, Viral
keywords: Adenovirus; Outbreak