title: Clinico-microbiological Profile and Visual outcome in Traumatic Endophthalmitis following Pars Plana Vitrectomy at a Tertiary Eye Care Centre of Nepal.
abstract: BACKGROUND
  Endophthalmitis is a potentially devastating ocular complication of perforating eye injury (PEI) where prompt intervention can save some vision. This study aims to explore the clinico-microbiologic profile and visual outcome following pars plana vitrectomy (PPV) in traumatic endophthalmitis.
  
  
  METHODS
  This is a retrospective interventional case series study conducted at a tertiary eye care centre of Nepal. A total of 49 consecutive cases (49 eyes) of endophthalmitis following PEI, who underwent PPV from January 2007 to June 2010 were included in the study.
  
  
  RESULTS
  Mean age was 14.7 years (S.D. 14.27). Twenty seven patients (55%) were of age group below 10 years. Male to female ratio was 2.75:1. Mean duration of presentation was 8.9 days. Nineteen eyes (36.73%) had injuries with wooden sticks, followed by injury with metallic objects in 16 patients (32.56%). PEI involving zone I was found in 31 eyes (63.25%). The retained intraocular foreign body was found in seven patients (14.2%). The post operative vision improved in almost 24 cases (49%) with visual recovery of 20/200 and better in six cases (12.24%). The vitreous culture was positive in five cases (12.8%) with predominant streptococcus pneumonia in four cases (10.25%).
  
  
  CONCLUSIONS
  Children were the mostly affected group with males outnumbering females. Wooden sticks and metallic objects were the commonest insulting agents. Despite the late presentation and predominant zone I injury, eye could be salvaged in majority with visual recovery of 20/200 and better in six cases (12.24%).
authors.affiliation: Tilganga Institute of Ophthalmology, Gaushala, Kathmandu, Nepal.
authors.forename: R
authors.initials: R
authors.lastname: Thapa
authors.affiliation: Tilganga Institute of Ophthalmology, Gaushala, Kathmandu, Nepal.
authors.forename: G
authors.initials: G
authors.lastname: Paudyal
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D009877:Endophthalmitis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology / Q000382:microbiology; D005129:Eye Foreign Bodies / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D015807:Eye Injuries, Penetrating / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D009390:Nepal / Q000453:epidemiology; D017063:Outcome Assessment, Health Care; D012189:Retrospective Studies; D062606:Tertiary Care Centers / Q000706:statistics & numerical data; D014792:Visual Acuity; D014821:Vitrectomy / Q000009:adverse effects / Q000379:methods
chemical_list: D000900:Anti-Bacterial Agents
keywords: endophthalmitis; intra-ocular foreign body; perforating eye injury; vitrectomy .