title: Cognitive Behavior Therapy for psychosis based Guided Self-help (CBTp-GSH) delivered by frontline mental health professionals: Results of a feasibility study.
abstract: Availability of Cognitive Behavior Therapy for psychosis (CBTp) is limited in spite of strong evidence base. The purpose of this study was to determine the feasibility of a CBTp based Guided Self-help (CBTp-GSH) in comparison to Treatment As Usual (TAU). The secondary outcomes were a reduction of symptoms of schizophrenia using Positive and Negative Symptom Scale (PANSS) & Disability (WHO DAS 2.0). A total of 33 adults with a DSM-IV diagnosis of schizophrenia was recruited from community mental health services in Kingston, ON, Canada, and randomly assigned to the 12-16week intervention with TAU (Treatment), or TAU alone (Control). End of therapy (16weeks) comparisons between the two groups were made on an Intention To Treat (ITT) basis. Post-intervention scores on measures of psychopathology were compared using Analysis of Covariance (ANCOVA) to adjust for baseline measurements. Recruitment proved feasible, retention rates were high and participants reported a high level of acceptability. There was significant "treatment group by outcome interaction" for Positive and Negative Symptoms, General Psychopathology, measures of disability, such that individuals who received the Treatment improved more than those in Control group. The results of this feasibility study indicate that CBTp based Guided Self-help is feasible and acceptable to the participants, and it can lead to improvement in psychopathology and the level of disability. Individuals in this study had a moderate degree of psychopathology and relatively low level of disability and, therefore, caution is warranted in applying these results to individuals with severe symptoms and with high levels of disability. An adequately powered randomized controlled trial of the intervention is warranted.
authors.affiliation: Queens University, Kingston, ON, Canada. Electronic address: farooqnaeem@yahoo.com.
authors.forename: Farooq
authors.initials: F
authors.lastname: Naeem
authors.affiliation: Queens University, Kingston, ON, Canada.
authors.forename: Rupy
authors.initials: R
authors.lastname: Johal
authors.affiliation: Queens University, Kingston, ON, Canada.
authors.forename: Claire
authors.initials: C
authors.lastname: McKenna
authors.affiliation: Southern Health NHS Foundation Trust, Hampshire, UK.
authors.forename: Shanaya
authors.initials: S
authors.lastname: Rathod
authors.affiliation: Queens University, Kingston, ON, Canada.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ayub
authors.affiliation: University of Montreal, Montreal, Canada.
authors.forename: Tania
authors.initials: T
authors.lastname: Lecomte
authors.affiliation: Manchester University, Manchester, UK.
authors.forename: Nusrat
authors.initials: N
authors.lastname: Husain
authors.affiliation: Southampton University, Southampton, UK.
authors.forename: David
authors.initials: D
authors.lastname: Kingdon
authors.affiliation: Keele University, UK.
authors.forename: Saeed
authors.initials: S
authors.lastname: Farooq
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015928:Cognitive Behavioral Therapy / Q000379:methods* / Q000592:standards*; D005240:Feasibility Studies; D005260:Female; D006281:Health Occupations / Q000592:standards*; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000523:psychology / Q000534:rehabilitation*; D012189:Retrospective Studies; D012657:Self-Help Groups / Q000592:standards*; D016037:Single-Blind Method; D016896:Treatment Outcome
keywords: CBT; Guided; Psychosis; Schizophrenia; Self-help