title: Slowing down theGrandTouringPrototype speed of cancer cells.
abstract: Enzymes involved inde novoproduction of guanosine triphosphate (GTP) have been recently revealed as integral components of melanoma progression through modulation of the activity of small GTPases. Here, we discuss the biology and therapeutic implications of these findings.
authors.affiliation: Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York, 14263.
authors.forename: Anna
authors.initials: A
authors.lastname: Bianchi-Smiraglia
authors.affiliation: Department of Cell Stress Biology, Roswell Park Cancer Institute, Buffalo, New York, 14263.
authors.forename: Mikhail A
authors.initials: MA
authors.lastname: Nikiforov