title: Application of an automated natural language processing (NLP) workflow to enable federated search of external biomedical content in drug discovery and development.
abstract: External content sources such as MEDLINE(®), National Institutes of Health (NIH) grants and conference websites provide access to the latest breaking biomedical information, which can inform pharmaceutical and biotechnology company pipeline decisions. The value of the sites for industry, however, is limited by the use of the public internet, the limited synonyms, the rarity of batch searching capability and the disconnected nature of the sites. Fortunately, many sites now offer their content for download and we have developed an automated internal workflow that uses text mining and tailored ontologies for programmatic search and knowledge extraction. We believe such an efficient and secure approach provides a competitive advantage to companies needing access to the latest information for a range of use cases and complements manually curated commercial sources.
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA. Electronic address: robin_mcentire@merck.com.
authors.forename: Robin
authors.initials: R
authors.lastname: McEntire
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA.
authors.forename: Debbie
authors.initials: D
authors.lastname: Szalkowski
authors.affiliation: Linguamatics Solutions, USA.
authors.forename: James
authors.initials: J
authors.lastname: Butler
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA.
authors.forename: Michelle S
authors.initials: MS
authors.lastname: Kuo
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA.
authors.forename: Meiping
authors.initials: M
authors.lastname: Chang
authors.affiliation: Linguamatics Solutions, USA.
authors.forename: Man
authors.initials: M
authors.lastname: Chang
authors.affiliation: Informatics IT, Merck & Co., USA.
authors.forename: Darren
authors.initials: D
authors.lastname: Freeman
authors.affiliation: Linguamatics Limited, UK.
authors.forename: Sarah
authors.initials: S
authors.lastname: McQuay
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA.
authors.forename: Jagruti
authors.initials: J
authors.lastname: Patel
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA.
authors.forename: Michael
authors.initials: M
authors.lastname: McGlashen
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA. Electronic address: wdcornell@yahoo.com.
authors.forename: Wendy D
authors.initials: WD
authors.lastname: Cornell
authors.affiliation: Knowledge Discovery/Knowledge Management, Merck & Co., USA.
authors.forename: Jinghai James
authors.initials: JJ
authors.lastname: Xu
mesh_terms: D057225:Data Mining; D055808:Drug Discovery; D007256:Information Systems; D009323:Natural Language Processing