title: Acetophenones Isolated from Acronychia pedunculata and their Anti-proliferative Activities.
abstract: Study of the chemical constituents of Acronychia pedunculata (L.) Miq. (Rutaceae) stems collected in Taiwan led to the isolation and identification of eight known and three new acetophenones, named acrophenone A (1), B (2), and C (3). Of them, acrovestone (5), acropyrone (6) and acrovestenol (7), which are dimer compounds, strikingly inhibited the proliferation of human leukemia cell lines.
authors.forename: Chihiro
authors.initials: C
authors.lastname: Ito
authors.forename: Takuya
authors.initials: T
authors.lastname: Matsui
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Ban
authors.forename: Tian-Shung
authors.initials: TS
authors.lastname: Wu
authors.forename: Masataka
authors.initials: M
authors.lastname: Itoigawa
mesh_terms: D000098:Acetophenones / Q000737:chemistry* / Q000494:pharmacology*; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D018547:Plant Stems / Q000737:chemistry; D027821:Rutaceae / Q000737:chemistry*
chemical_list: D000098:Acetophenones; D000972:Antineoplastic Agents, Phytogenic