title: The Feasibility of Recruiting and Retaining Perinatal Latinas in a Biomedical Study Exploring Neuroendocrine Function and Postpartum Depression.
abstract: This study evaluates the feasibility of enrolling and retaining perinatal immigrant and U.S.-born Latinas in a laboratory-based study that includes the collection of biomarkers implicated in the development of postpartum depression. This prospective study followed Latinas from third trimester of pregnancy to 12 weeks postpartum. Women were enrolled during pregnancy and interviewed at 4, 8 and 12 weeks postpartum. Demographic information, depression status and breastfeeding practices were ascertained using validated Spanish- and English-measures. Blood samples were collected at the 8-week postpartum laboratory visit during infant feeding and pain testing. Feasibility was demonstrated with 85 % retention of the original 34 prenatal women enrolled in the study. The majority (88 %) of women enrolled attended the 8-week laboratory visit regardless of depression status. This is the first study to demonstrate feasibility of enrolling and retaining depressed and nondepressed perinatal immigrant and U.S.-born Latinas in biomedical research.
authors.affiliation: Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign, 1204 Fourth Street, Khan 2015, Champaign, IL, 61820, USA. laracini@illinois.edu.|Department of Psychiatry, UNC School of Medicine, University of North Carolina at Chapel Hill, 101 Manning Drive, 10514 Neurosciences Hospital, Chapel Hill, NC, 27599-7160, USA. laracini@illinois.edu.
authors.forename: Sandraluz
authors.initials: S
authors.lastname: Lara-Cinisomo
authors.affiliation: Department of Psychiatry, UNC School of Medicine, University of North Carolina at Chapel Hill, 101 Manning Drive, 10514 Neurosciences Hospital, Chapel Hill, NC, 27599-7160, USA.
authors.forename: Jasmine
authors.initials: J
authors.lastname: Plott
authors.affiliation: Department of Psychiatry, UNC School of Medicine, University of North Carolina at Chapel Hill, 101 Manning Drive, 10514 Neurosciences Hospital, Chapel Hill, NC, 27599-7160, USA.
authors.forename: Karen
authors.initials: K
authors.lastname: Grewen
authors.affiliation: Department of Psychiatry, UNC School of Medicine, University of North Carolina at Chapel Hill, 101 Manning Drive, 10514 Neurosciences Hospital, Chapel Hill, NC, 27599-7160, USA.
authors.forename: Samantha
authors.initials: S
authors.lastname: Meltzer-Brody
mesh_terms: D000328:Adult; D015415:Biomarkers; D001942:Breast Feeding / Q000208:ethnology; D003863:Depression / Q000097:blood / Q000208:ethnology; D019052:Depression, Postpartum / Q000097:blood* / Q000208:ethnology*; D054242:Emigrants and Immigrants; D005260:Female; D006630:Hispanic or Latino; D006801:Humans; D009035:Mothers; D009490:Neurosecretory Systems / Q000503:physiopathology*; D018579:Patient Selection; D018743:Perinatal Care; D011446:Prospective Studies; D012107:Research Design; D012959:Socioeconomic Factors
chemical_list: D015415:Biomarkers
keywords: Biomedical study; Feasibility; Latina; Perinatal women; Postpartum depression