title: A SEVEN-YEAR-OLD MALE WITH CIRCULATING RED BLOOD CELLS SHOWING A THERMAL INJURY-LIKE MORPHOLOGY.
abstract: A seven-year-old African-American male presented with a history of hematuria, proteinuria, jaundice, and anemia occasionally treated with transfusions since early childhood. The family history included a father and sister with similar symptoms of anemia, both of which had been diagnosed with hereditary pyropoikilocytosis. Due to the patient's family history and symptoms indicating a possible hematologic problem, a blood draw was performed. Laboratory studies showed an elevated alkaline phosphatase and bilirubin, and hemolytic anemia with unusual erythrocyte indices. The patient's vital signs and abdominal ultrasound were normal, and he had no known allergies. Examination of the patient's peripheral blood smear revealed extreme erythrocyte poikilocytosis with bizarre forms resembling the erythrocyte morphology sometimes seen in individuals with severe thermal burns.
authors.affiliation: Dr. Shackelford is associated with the Department of Pathology.
authors.forename: R
authors.initials: R
authors.lastname: Shackelford
authors.affiliation: Dr. Dansari is affililated with the Feist Weiller Cancer Center, LSU Health Shreveport, Shreveport, LA;
authors.forename: J
authors.initials: J
authors.lastname: Ansari
authors.affiliation: Dr. Veillon is associated with the Department of Pathology.
authors.forename: D
authors.initials: D
authors.lastname: Veillon
authors.forename: M
authors.initials: M
authors.lastname: Ong
authors.affiliation: Mr. Jusino is associated with Clinical Molecular Pathology Consultative Services, LSU Health Shreveport, Shreveport, LA.
authors.forename: T
authors.initials: T
authors.lastname: Jusino
authors.affiliation: Dr. Jeroudi is associated with Department of Pediatrics, Section of Hematology/Oncology at the Louisiana State University Health Sciences Center, Shreveport, LA;
authors.forename: M
authors.initials: M
authors.lastname: Jeroudi
authors.affiliation: Dr. Cotelingam is associated with the Department of Pathology.
authors.forename: J
authors.initials: J
authors.lastname: Cotelingam
mesh_terms: D000745:Anemia, Hemolytic, Congenital; D002056:Burns / Q000175:diagnosis; D002648:Child; D004612:Elliptocytosis, Hereditary / Q000175:diagnosis*; D004912:Erythrocytes; D004913:Erythrocytes, Abnormal; D006801:Humans; D008297:Male