title: Synthesis, Crystal Structure, Spectroscopic Properties, and Interaction with Ct-DNA of Zn(II) with 2-Aminoethanethiol Hydrochloride Ligand.
abstract: The zinc(II) complex (C2H6NS)2Zn·ZnCl2 was synthesized with 2-aminoethanethiol hydrochloride and zinc sulfate heptahydrate as the raw materials in aqueous solution. The composition and structure of the complex were characterized by elemental analysis, infrared spectra, single crystal X-ray diffraction, and thermogravimetry. The crystal structure of the zinc(II) complex belongs to monoclinic system, space group P  21/n, with cell parameters of a = 0.84294(4), b = 0.83920(4), c = 1.65787(8) nm, Z = 2, and D = 2.041 g/cm(3). In this paper, the interaction of complex with Ct-DNA was investigated by UV-visible and viscosimetric techniques. Upon addition of the complex, important changes were observed in the characteristic UV-Vis bands (hyperchromism) of calf thymus DNA and some changes in specific viscosity. The experimental results showed that the complex is bound to DNA intercalative (intercalation binding).
authors.affiliation: College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
authors.forename: Xu-Gang
authors.initials: XG
authors.lastname: Shu
authors.affiliation: College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
authors.forename: Chun-Li
authors.initials: CL
authors.lastname: Wu
authors.affiliation: College of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China.
authors.forename: Cui-Jin
authors.initials: CJ
authors.lastname: Li
authors.affiliation: College of Light Industry and Chemical Engineering, Guangdong University of Technology, Guangzhou 510006, China.
authors.forename: Min
authors.initials: M
authors.lastname: Zhang
authors.affiliation: College of Light Industry and Chemical Engineering, Guangdong University of Technology, Guangzhou 510006, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Wan
authors.affiliation: Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha 410125, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Wu