title: Mixed vitiligo of Blaschko lines: a newly discovered presentation of vitiligo responsive to combination treatment.
abstract: Vitiligo, depigmenting disorder of the skin and mucous membranes, affects up to 1% of the population worldwide. It is classified into four major types: segmental, non-segmental, mixed, and unclassified type. Non-segmental vitiligo refers to non-dermatomal distribution of lesions, while dermatomal distribution of lesions is present in patients with segmental vitiligo. Segmental vitiligo can also follow Blaschko lines - pathways of epidermal cell migration and proliferation during the development of the fetus. Here, we present patient with segmental and non-segmental vitiligo following Blaschko lines with excellent therapeutic response to combined therapy. Prior to our report, a case of segmental and non-segmental vitiligo followed by Blaschko lines was never described, therefore we suggest the term "mixed vitiligo of Blaschko lines" to describe this entity. This is also a rare case in which 90% repigmentation was achieved in patient with segmental and nonsegmental vitiligo following Blaschko lines in only 2 months of combined therapy.
authors.affiliation: Croatian Vitiligo Association, Huga Badalica 26, Zagreb, Croatia.|Dermatology and Venereology Division, Guglielmo Marconi University, Via Plinio, 44, 00193, Roma, Italy.
authors.forename: Maja
authors.initials: M
authors.lastname: Kovacevic
authors.affiliation: Croatian Vitiligo Association, Huga Badalica 26, Zagreb, Croatia.|Department of Clinical Medicine, University of Applied Health Sciences, Mlinarska 38, Zagreb, Croatia.
authors.forename: Andrija
authors.initials: A
authors.lastname: Stanimirovic
authors.affiliation: Department of Pathology, University Hospital Center "Sestre milosrdnice", Vinogradska cesta 29, Zagreb, Croatia.
authors.forename: Majda
authors.initials: M
authors.lastname: Vucic
authors.affiliation: Dermatology and Venereology Division, Guglielmo Marconi University, Via Plinio, 44, 00193, Roma, Italy.|Applied Biology, Inc., Irvine, California.
authors.forename: Andy
authors.initials: A
authors.lastname: Goren
authors.affiliation: Department of Dermatology and Venereology, University Hospital Center "Sestre milosrdnice", Vinogradska cesta 29, Zagreb, Croatia.
authors.forename: Mirna
authors.initials: M
authors.lastname: Situm
authors.affiliation: Zagreb School of Medicine, University of Zagreb, Šalata 3, Croatia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Lukinovic Skudar
authors.affiliation: Dermatology and Venereology Division, Guglielmo Marconi University, Via Plinio, 44, 00193, Roma, Italy.
authors.forename: Torello
authors.initials: T
authors.lastname: Lotti
mesh_terms: D000328:Adult; D000975:Antioxidants / Q000627:therapeutic use; D002990:Clobetasol / Q000627:therapeutic use; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D010789:Phototherapy; D014820:Vitiligo / Q000473:pathology / Q000628:therapy*
chemical_list: D000975:Antioxidants; D002990:Clobetasol
keywords: Blaschko lines; mixed vitiligo; vitiligo