title: Stance Postural Strategies in Patients with Chronic Inflammatory Demyelinating Polyradiculoneuropathy.
abstract: BACKGROUND
  Polyneuropathy leads to postural instability and an increased risk of falling. We investigated how impaired motor impairment and proprioceptive input due to neuropathy influences postural strategies.
  
  
  METHODS
  Platformless bisegmental posturography data were recorded in healthy subjects and patients with chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Each subject stood on the floor, wore a head and a hip electromagnetic tracker. Sway amplitude and velocity were recorded and the mean direction difference (MDD) in the velocity vector between trackers was calculated as a flexibility index.
  
  
  RESULTS
  Head and hip postural sway increased more in patients with CIDP than in healthy controls. MDD values reflecting hip strategies also increased more in patients than in controls. In the eyes closed condition MDD values in healthy subjects decreased but in patients remained unchanged.
  
  
  CONCLUSIONS
  Sensori-motor impairment changes the balance between postural strategies that patients adopt to maintain upright quiet stance. Motor impairment leads to hip postural strategy overweight (eyes open), and prevents strategy re-balancing when the sensory context predominantly relies on proprioceptive input (eyes closed).
authors.affiliation: Neurology and Neurophysiopathology Unit, Sandro Pertini Hospital, Rome, Italy.
authors.forename: Steno
authors.initials: S
authors.lastname: Rinalduzzi
authors.affiliation: Neurology and Neurophysiopathology Unit, Sandro Pertini Hospital, Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Serafini
authors.affiliation: Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Capozza
authors.affiliation: Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy.
authors.forename: Neri
authors.initials: N
authors.lastname: Accornero
authors.affiliation: Neurosurgery Unit, Policlinico Umberto I, Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Missori
authors.affiliation: Institute of Neurology, Department of Neurosciences, Ophthalmology and Genetics, University of Genova, Genova, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Trompetto
authors.affiliation: Department of Neurology and Psychiatry, Sapienza University of Rome, Rome, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Fattapposta
authors.affiliation: Academic Neurology Unit, A. Fiorini Hospital, Department of Medical-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Terracina (LT), Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Currà
mesh_terms: D000328:Adult; D000368:Aged; D001696:Biomechanical Phenomena; D056228:Feedback, Sensory; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D018908:Muscle Weakness / Q000209:etiology / Q000503:physiopathology; D018482:Muscle, Skeletal / Q000294:innervation / Q000503:physiopathology; D009431:Neural Conduction; D026741:Physical Therapy Modalities; D020277:Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / Q000150:complications* / Q000503:physiopathology; D004856:Postural Balance; D011187:Posture; D012678:Sensation Disorders / Q000209:etiology / Q000628:therapy*; D020886:Somatosensory Disorders / Q000209:etiology / Q000628:therapy*; D014785:Vision, Ocular; D055815:Young Adult