title: [Transdermal estrogen spray in therapy of postmenopausal syndrome].
abstract: OBJECTIVE
  To show possibilities of new application method of estrogen replacement therapy - mettered-dose transdermal spray.
  
  
  METHODS
  Review articleResults: Transdermal spray contains 1.53 mg estradiol in one dose. It gives possibility of individual aproach in estradiol application 1, 2 or 3 doses daily. About 85% of patients showed the significant reduction of hot flushes. Perfect safety profile is predicted especially in cardiovascular point.
authors.forename: T
authors.initials: T
authors.lastname: Fait
mesh_terms: D000279:Administration, Cutaneous; D000336:Aerosols; D002979:Climacteric / Q000187:drug effects*; D018153:Czech Republic; D004958:Estradiol / Q000008:administration & dosage*; D015914:Estrogen Replacement Therapy / Q000379:methods*; D005260:Female; D019584:Hot Flashes / Q000188:drug therapy*; D006801:Humans; D008875:Middle Aged
chemical_list: D000336:Aerosols; D004958:Estradiol
keywords: hormone replacement therapy; mettered-dose transdermal spray; perimenopausal symptoms; tromboembolic desease.