title: Effects of Salivary Oxidative Markers on Edentulous Patients' Satisfaction with Prosthetic Denture Treatments: A Pilot Study.
abstract: OBJECTIVE
  The purpose of this study was to assess relationships among periodontal conditions, salivary antioxidant levels, and patients' satisfaction with their prostheses.
  
  
  METHODS
  This study was conducted at the Division of Prosthodontics, Department of Dentistry, Taipei Medical University Hospital. The periodontal condition of patients was based on an assessment of the plaque index (PI) and gingival index (GI). The pH value, flow rate, and buffer capacity of the saliva were estimated. The salivary total antioxidant status (TAS) and superoxide dismutase (SOD) level were also determined. Patients' satisfaction with prosthetic treatments was evaluated using the Chinese version of the short-form Oral Health Impact Profile (OHIP-14C). A multivariate regression model was used to determine whether patients' satisfaction with prosthetic treatment was affected by their oral health status.
  
  
  RESULTS
  In total, 35 edentulous patients were recruited. In the Spearman correlation analysis, salivary pH (r = -0.36, p = 0.03) and the buffer ability (r = -0.48, p<0.01) were associated with OHIP-14C scores. In the multivariate analysis, patients who had a higher GI also had a higher score of physical disabilities (β = 1.38, p = 0.04). Levels of SOD increased with the scores of psychological discomfort (β = 0.33 U/g protein, p = 0.04).
  
  
  CONCLUSIONS
  This study suggested that both the GI and SOD levels were associated with patients' satisfaction with prosthetic treatments. To the best of our knowledge, this is the first study to elucidate the relationship between OHIP scores and salivary oxidative markers in edentulous patients.
authors.affiliation: College of Public Health and Nutrition, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Chia-Huang
authors.initials: CH
authors.lastname: Chang
authors.affiliation: School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.|Division of Periodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Chang-Yu
authors.initials: CY
authors.lastname: Lee
authors.affiliation: School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Sheng-Wei
authors.initials: SW
authors.lastname: Feng
authors.affiliation: School of Nursing, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Nae-Fang
authors.initials: NF
authors.lastname: Miao
authors.affiliation: School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Pei-Huan
authors.initials: PH
authors.lastname: Lin
authors.affiliation: School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.|Division of Prosthodontics, Department of Dentistry, Taipei Medical University Hospital, Taipei, 110, Taiwan.
authors.forename: Che-Tong
authors.initials: CT
authors.lastname: Lin
authors.affiliation: College of Public Health and Nutrition, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Shin-Han
authors.initials: SH
authors.lastname: Tsai
authors.affiliation: School of Oral Hygiene, College of Oral Medicine, Taipei Medical University, Taipei, 110, Taiwan.
authors.forename: Yung-Kai
authors.initials: YK
authors.lastname: Huang
mesh_terms: D000368:Aged; D000975:Antioxidants / Q000032:analysis*; D015415:Biomarkers / Q000032:analysis; D003774:Dental Plaque Index; D003824:Denture, Complete / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D009066:Mouth, Edentulous / Q000523:psychology* / Q000628:therapy; D017060:Patient Satisfaction; D010512:Periodontal Index; D010865:Pilot Projects; D012463:Saliva / Q000737:chemistry*; D013482:Superoxide Dismutase / Q000032:analysis; D011795:Surveys and Questionnaires
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D013482:Superoxide Dismutase