title: According to which factors in severe traumatic brain injury craniectomy could be beneficial.
abstract: BACKGROUND
  To investigate the clinical outcome at 101 patients undergoing decompressive craniectomy (DC) after severe traumatic brain injury (TBI).
  
  
  METHODS
  Age, Glasgow Coma Scale (GCS) at the time of intubation, and the intraoperative intracranial pressure (ICP) were recorded. Formal DC was performed in all cases and the square surface of bone flap was calculated in cm(2) based on the length and the width from computed tomography scan.
  
  
  RESULTS
  The difference of good neurological recovery (Glasgow outcome score 4-5), between patients with ICP ≤20 mmHg, GCS ≥5, age ≤60 years, and bone flap ≥130 cm(2) and those with ICP >20 mmHg, GCS <5, age >60 years, and bone flap <130 cm(2), was statistically significant.
  
  
  CONCLUSIONS
  Although the application of DC in severe TBI is controversial and the population in this study is small, our study demonstrates the threshold of the specific factors (patient age, ICP and GCS on the day of the surgery and the size of the bone flap) which may help in the decision of performing DC. Furthermore, this study proves that the different combinations and mainly at the same time involvement of all prognostic parameters (age <60, GCS <5, bone flap ≥130 cm(2), and ICP ≤20 at time of DC surgery) allow a better outcome.
authors.affiliation: Department of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Fotakopoulos
authors.affiliation: Department of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
authors.forename: Eleni
authors.initials: E
authors.lastname: Tsianaka
authors.affiliation: Department of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Vagkopoulos
authors.affiliation: Department of Neurosurgery, University Hospital of Thessaly, University Hospital of Larissa, Biopolis, 41110 Larissa, Thessaly, Greece; Center for Research and Technology of Thessaly, 38500 Larissa, Greece.
authors.forename: Kostas N
authors.initials: KN
authors.lastname: Fountas
keywords: Brain trauma; decompressive craniectomy; severe brain injury