title: Lack of Energy and Negative Health-Related Outcomes in Nursing Home Residents: Results From the INCUR Study.
abstract: "Lack of energy" or anergia is a common complaint associated with adverse outcomes in older people. There is a lack of knowledge on this symptom in the nursing home (NH) setting. The aim of this study was to investigate whether lack of energy was associated with hospitalization and mortality in NH residents.
  
  
  
  Longitudinal observational cohort study.
  
  
  
  A total of 575 NH residents (72% women) in 13 French NHs from the Incidence of pNeumonia and related ConseqUences in nursing home Residents (INCUR) study cohort.
  
  
  
  Lack of energy was measured at the baseline visit as part of the 10-item Geriatric Depression Scale. Unadjusted and adjusted Cox proportional hazard regression models were performed to test the association of lack of energy with hospitalization events and mortality over 12 months of follow-up.
  
  
  
  The mean age of the study sample was 86.3 (SD = 7.5) years. At the baseline, 250 (43.5%) residents complained about lack of energy. Overall, 192 (33.4%) individuals experienced at least 1 hospitalization event and 98 (17.0%) died during the 12-month follow-up. Lack of energy was significantly associated with a higher risk of hospitalization (HR 1.35; 95% CI 1.02-1.80; P = .03), even after adjustment for potential confounders (HR 1.41; 95% CI 1.04-1.91; P = .02). No statistically significant association was found between lack of energy and 12-month mortality.
  
  
  
  Lack of energy is a predictor of hospitalization in older people living in NHs. It may be considered a relevant clinical feature for identifying individuals at risk of adverse health outcomes, thus potentially serving as a screening tool for subsequently conducting a comprehensive geriatric assessment in this highly vulnerable and complex population.
authors.affiliation: Department of Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy; Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France. Electronic address: el.zengarini@hotmail.it.
authors.forename: Elisa
authors.initials: E
authors.lastname: Zengarini
authors.affiliation: Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; Department of Epidemiology & Biostatistics, EMGO+ Institute for Health and Care Research, VU University Medical Center, Amsterdam, the Netherlands.
authors.forename: Emiel O
authors.initials: EO
authors.lastname: Hoogendijk
authors.affiliation: Clinical and Epidemiological Research Department, National Geriatric Institute, Mexico City, Mexico.
authors.forename: Mario U
authors.initials: MU
authors.lastname: Pérez-Zepeda
authors.affiliation: Department of Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy.
authors.forename: Carmelinda
authors.initials: C
authors.lastname: Ruggiero
authors.affiliation: Department of Medicine, Institute of Gerontology and Geriatrics, University of Perugia, Perugia, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Mecocci
authors.affiliation: Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; INSERM UMR1027, Université Toulouse III - Paul Sabatier, Toulouse, France.
authors.forename: Bruno
authors.initials: B
authors.lastname: Vellas
authors.affiliation: Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France; INSERM UMR1027, Université Toulouse III - Paul Sabatier, Toulouse, France.
authors.forename: Matteo
authors.initials: M
authors.lastname: Cesari
mesh_terms: D000293:Adolescent; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005544:Forecasting; D016330:Frail Elderly; D015577:Geriatric Assessment / Q000379:methods; D006760:Hospitalization / Q000639:trends; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D009026:Mortality / Q000639:trends; D009735:Nursing Homes; D016016:Proportional Hazards Models; D018570:Risk Assessment
keywords: Lack of energy; hospitalization; mortality; nursing home