title: Vaccination During Pregnancy.
abstract: Active immunization during pregnancy for maternal and neonatal benefit is a remarkably promising strategy to reduce infectious morbidity in both women and infants. The aim of this review is to present current clinical guidelines for vaccination during pregnancy and review evidence-based strategies for the implementation of maternal immunization recommendations. Observational studies, clinical trials, cost-effectiveness analyses, systematic reviews, and meta-analyses were evaluated to generate the evidence base for this review. In addition, recommendations from major national professional and public health organizations were examined. We present current clinical recommendations for vaccination during pregnancy and review medical and public health strategies to implement these guidelines. We also discuss a research agenda to advance the field of maternal immunization and achieve further improvements in maternal and child health.
authors.affiliation: Assistant Professor, Department of Obstetrics and Gynecology, Institute for Healthcare Policy and Innovation, University of Michigan, Ann Arbor, MI.
authors.forename: Michelle H
authors.initials: MH
authors.lastname: Moniz
authors.affiliation: Associate Professor, Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital of the University of Pittsburgh Medical Center, Pittsburgh, PA.
authors.forename: Richard H
authors.initials: RH
authors.lastname: Beigi
mesh_terms: D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines / Q000009:adverse effects; D019317:Evidence-Based Medicine; D005260:Female; D049672:History, 19th Century; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects; D010567:Pertussis Vaccine / Q000009:adverse effects; D010817:Physician-Patient Relations; D017410:Practice Guidelines as Topic; D011247:Pregnancy; D014611:Vaccination / Q000266:history
chemical_list: D022681:Diphtheria-Tetanus-acellular Pertussis Vaccines; D007252:Influenza Vaccines; D010567:Pertussis Vaccine