title: Extragenital bullous lichen sclerosus.
abstract: Lichen sclerosus (LS) is a chronic, inflammatory dermatosis that is characterized by pruritic, white, atrophic plaques that classically affect the anogenital region of postmenopausal women. Extragenital involvement also may occur with several reported morphologic variants. Extragenital bullous LS is a rare variant, which presents as flaccid bullae that favor the trunk and proximal aspects of the extremities. The treatment of extragenital bullous LS is similar to that of genital LS. However, extragenital LS is often less responsive and may present a therapeutic challenge. We describe a 65-year-old woman with a two-year history of vulvar and extragenital LS, who developed a bullous eruption within a pre-existing patch of lichen sclerosis on the breast. We review the clinical and histopathologic features of extragenital bullous LS and discuss current treatment options, which include those for recalcitrant cases.
authors.affiliation: New York University School of Medicine.
authors.forename: Nicola A
authors.initials: NA
authors.lastname: Quatrano
authors.forename: Marianna
authors.initials: M
authors.lastname: Shvartsbeyn
authors.forename: Shane A
authors.initials: SA
authors.lastname: Meehan
authors.forename: Rhonda
authors.initials: R
authors.lastname: Pomerantz
authors.forename: Miriam Keltz
authors.initials: MK
authors.lastname: Pomeranz
mesh_terms: D000328:Adult; D001706:Biopsy; D005121:Extremities / Q000473:pathology; D005260:Female; D006801:Humans; D018459:Lichen Sclerosus et Atrophicus / Q000473:pathology*; D012872:Skin Diseases, Vesiculobullous / Q000473:pathology*; D060726:Torso / Q000473:pathology