title: BK polyoma virus infection and renal disease in non-renal solid organ transplantation.
abstract: BK virus (BKV) is a non-enveloped DNA virus of the polyomaviridae family that causes an interstitial nephritis in immunosuppressed patients. BKV nephropathy is now a leading cause of chronic kidney disease and early allograft failure following kidney transplantation. It is also known to cause renal disease with a progressive decline in kidney function in non-renal solid organ transplant (NRSOT) recipients, although the disease may not be recognized nor its impact appreciated in this patient population. In this report, we review the existing literature to highlight our current understanding of its incidence in NRSOT populations, the approaches to diagnosis and the potential treatment options.
authors.affiliation: Department of Internal Medicine , University of Iowa, Carver College of Medicine , Iowa City, IA , USA.
authors.forename: Sarat
authors.initials: S
authors.lastname: Kuppachi
authors.affiliation: Department of Internal Medicine , University of Iowa, Carver College of Medicine , Iowa City, IA , USA.
authors.forename: Deepkamal
authors.initials: D
authors.lastname: Kaur
authors.affiliation: Department of Pathology , University of Iowa, Carver College of Medicine , Iowa City, IA , USA.
authors.forename: Danniele G
authors.initials: DG
authors.lastname: Holanda
authors.affiliation: Department of Internal Medicine, University of Iowa, Carver College of Medicine, Iowa City, IA, USA; VA Medical Center, Iowa City, IA, USA.
authors.forename: Christie P
authors.initials: CP
authors.lastname: Thomas
keywords: BK polyoma virus; immunosuppression complication; interstitial nephritis; non-renal solid organ transplantation