title: Consequences of Correcting Intelligence Quotient for Prematurity at Age 5 Years.
abstract: To determine the effects of correcting for prematurity on full scale IQ (FSIQ), verbal IQ (VIQ), performance IQ (PIQ), and processing speed quotient (PSQ) scores, and to investigate whether differences between corrected and uncorrected FSIQ are associated with gestational age (GA), FSIQ, and age at assessment.
  
  
  
  Single-center consecutive cohort study. Data were analyzed from 275 very preterm children (GA <30 weeks), born between January 2006 and December 2009 and assessed at 5 years corrected age as part of the neonatal long-term follow-up program, at the Emma Children's Hospital in Amsterdam, The Netherlands. Outcome measures were FSIQ, VIQ, PIQ, and PSQ, calculated for uncorrected and corrected age. Paired sample t tests, repeated measures ANOVA, and ANCOVA were performed to explore differences between corrected and uncorrected IQ.
  
  
  
  Differences between corrected and uncorrected FSIQ, VIQ, PIQ, and PSQ ranged from 0-15 IQ points. All corrected IQ scores were significantly higher than uncorrected IQ scores (all P values <.001). Differences were larger at lower GAs, for higher IQ scores, and if time of assessment lay near the starting point of a 3-month age band of the Wechsler Preschool and Primary Scale of Intelligence-Third Edition-Dutch Version.
  
  
  
  Given the great variation observed in differences between corrected and uncorrected IQ scores, an international standard as to what age correction is appropriate should be pursued.
authors.affiliation: Psychosocial Department, Academic Medical Center, Amsterdam, The Netherlands; Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands. Electronic address: s.vanveen@amc.uva.nl.
authors.forename: Sarit
authors.initials: S
authors.lastname: van Veen
authors.affiliation: Psychosocial Department, Academic Medical Center, Amsterdam, The Netherlands; Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Cornelieke S H
authors.initials: CS
authors.lastname: Aarnoudse-Moens
authors.affiliation: Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Anton H
authors.initials: AH
authors.lastname: van Kaam
authors.affiliation: Department of Pediatrics, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Jaap
authors.initials: J
authors.lastname: Oosterlaan
authors.affiliation: Department of Neonatology, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: Aleid G
authors.initials: AG
authors.lastname: van Wassenaer-Leemhuis
mesh_terms: D002675:Child, Preschool; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007360:Intelligence; D007361:Intelligence Tests; D008297:Male
keywords: Adjusted IQ; Cognition; Development; Follow-Up Studies; Gestational Age; Preterm Infant