title: Cardiac and arterial elastance and myocardial wall stress in children with pectus excavatum.
abstract: Pectus excavatum (PE) is one of the most common skeletal deformities of childhood. The study was undertaken to assess cardiac functions in children with PE.
  
  
  
  Echocardiography was performed on 32 children with PE and 40 age-matched healthy controls. The following parameters were monitored: meridional left ventricular (LV) wall stress (WSM), arterial elastance (Ea), LV elastance at end-systole derived by single beat (Ees(sb)), LV circumferential end-systolic wall stress (ESWSc), midwall shortening fraction (SFmid), predicted midwall fiber shortening for a measured fiber stress (midwall VCFc), myocardial fiber stress (MFS), LV end-systolic dimension (LVES), LV end-diastolic dimension (LVED) and end-systolic blood pressure (Pes), LV wall thickness at end-systole (hes). To assess the severity of PE, Haller index (HI) was calculated by computed tomography of the thorax.
  
  
  
  SFmid, ESWSc, midwall VCFc and MFS were lower in PE children than in controls. The degree to which the parameters SFmid, ESWSc, midwall VCFc and MFS were altered in PE children was 14.9, 27.5, 20.3 and 20.3%, respectively. The minimum HI value of children with PE was 2.00, the maximum value was 4.93 and the arithmetic mean was 2.62 ± 0.56. Of the 32 children, 14 (43.75%) demonstrated mild deformity, 15 (46.88%) showed moderate and only 3 (9.37%) had severe deformity. In children with PE, there was no statistically significant correlation between the cardiac data (ESWSc, midwall VCFc, MFS, Ea, Ees(sb), LVES, LVED, Pes, hes) and HI.
  
  
  
  We found ESWSc, MFS, midwall VCFc and SFmid to be lower in children with PE than in controls. We concluded that the myocardial contractility and afterload is affected in children with PE.
authors.affiliation: Department of Pediatrics, Bozok University Medical Faculty, Yozgat, Turkey uzdresra@gmail.com.
authors.forename: Esra
authors.initials: E
authors.lastname: Akyüz Özkan
authors.affiliation: Department of Pediatric Cardiology, Bozok University Medical Faculty, Yozgat, Turkey.
authors.forename: Hashem E
authors.initials: HE
authors.lastname: Khosrashahi
authors.affiliation: Department of Radiology, Bozok University Medical Faculty, Yozgat, Turkey.
authors.forename: Halil İbrahim
authors.initials: Hİ
authors.lastname: Serin
authors.affiliation: Department of Thoracic Surgery, Bozok University Medical Faculty, Yozgat, Turkey.
authors.forename: Bayram
authors.initials: B
authors.lastname: Metin
authors.affiliation: Department of Public Health, Bozok University Medical Faculty, Yozgat, Turkey.
authors.forename: Mahmut
authors.initials: M
authors.lastname: Kılıç
authors.affiliation: Department of Pediatrics, Bozok University Medical Faculty, Yozgat, Turkey.
authors.forename: U Aliye
authors.initials: UA
authors.lastname: Geçit
mesh_terms: D000293:Adolescent; D001158:Arteries / Q000503:physiopathology*; D001794:Blood Pressure / Q000502:physiology; D016022:Case-Control Studies; D002648:Child; D004452:Echocardiography; D004548:Elasticity; D005260:Female; D005660:Funnel Chest / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D006352:Heart Ventricles / Q000503:physiopathology; D006801:Humans; D008297:Male; D009200:Myocardial Contraction / Q000502:physiology*; D009206:Myocardium; D013318:Stroke Volume / Q000502:physiology; D016277:Ventricular Function, Left / Q000502:physiology*
keywords: Cardiac function; Children; Pectus excavatum