title: Low Seroprevalence Indicates Vulnerability of Eastern and Central Sudan to Infection with Chikungunya Virus.
abstract: Outbreaks of infections with chikungunya virus (CHIKV) have previously been reported from Sudan but the prevalence in the general population is unknown. We investigated the seroprevalence of CHIKV infection in 379 serum samples from patients with fever in the outpatient clinics of three hospitals in eastern and central Sudan. The seroprevalence was 1.8%, indicating that CHIKV infections are rare in these parts of Sudan. As the vector Aedes aegypti is endemic in this area, the population is at risk for a CHIKV epidemic.
authors.affiliation: 1 Institute of Virology, University Clinics and Faculty of Medicine, University of Leipzig , Leipzig, Germany .|2 Department of Microbiology, Faculty of Sciences, International University of Africa , Khartoum, Sudan .
authors.forename: Awadalkareem
authors.initials: A
authors.lastname: Adam
authors.affiliation: 3 Department of Medical Entomology, National Health Laboratory , Khartoum, Sudan .
authors.forename: Osama M E
authors.initials: OM
authors.lastname: Seidahmed
authors.affiliation: 4 Department of Virology, Paul-Ehrlich-Institut , Langen, Germany .
authors.forename: Christopher
authors.initials: C
authors.lastname: Weber
authors.affiliation: 4 Department of Virology, Paul-Ehrlich-Institut , Langen, Germany .
authors.forename: Barbara
authors.initials: B
authors.lastname: Schnierle
authors.affiliation: 5 Bernhard Nocht Institute for Tropical Medicine, WHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and WHO Collaborating Research Centre , Hamburg, Germany .
authors.forename: Jonas
authors.initials: J
authors.lastname: Schmidt-Chanasit
authors.affiliation: 6 Friedrich-Loeffler-Institut , Insel Riems, Germany .
authors.forename: Sven
authors.initials: S
authors.lastname: Reiche
authors.affiliation: 1 Institute of Virology, University Clinics and Faculty of Medicine, University of Leipzig , Leipzig, Germany .
authors.forename: Christian
authors.initials: C
authors.lastname: Jassoy
mesh_terms: D000293:Adolescent; D000328:Adult; D000330:Aedes; D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D065632:Chikungunya Fever / Q000097:blood / Q000453:epidemiology* / Q000276:immunology; D002646:Chikungunya virus / Q000276:immunology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005334:Fever / Q000821:virology; D006801:Humans; D007303:Insect Vectors; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies; D013397:Sudan / Q000453:epidemiology
chemical_list: D000914:Antibodies, Viral
keywords: Chikungunya; Epidemiology