title: The Improvement of Gastroesophageal Reflux Disease and Barrett's after Bariatric Surgery.
abstract: Obesity and gastroesophageal reflux disease (GERD) are prevalent in Western populations. In obese patients, high-resolution manometry often shows altered gastroesophageal pressure gradients, promoting retrograde gastric content flow into the esophagus and esophagogastric junction disruption, leading to a hiatal hernia. Hernia recurrence is higher in the obese, and recurrence is seen regardless of the operative approach used. Bariatric surgery is the gold-standard treatment for GERD in obese patients, and symptom improvement varies depending on the specific bariatric procedure performed, Roux-en-Y (RYGB), laparoscopic adjustable gastric banding (LAGB), or sleeve gastrectomy (SG). Studies have shown these surgeries significantly improve GERD, but RYGB had the greatest effect. Limited data is available examining the progression or regression of Barrett's following bariatric surgery. We currently recommend RYGB for morbidly obese patients with Barrett's esophagus.
authors.affiliation: Department of Surgery, Medical College of Wisconsin, 8701 Watertown Plank Rd, Milwaukee, WI, 53226, USA.
authors.forename: Tammy L
authors.initials: TL
authors.lastname: Kindel
authors.affiliation: The Center for Advanced Surgical Technology, Department of Surgery, University of Nebraska Medical Center, 986245 Nebraska Medical Center, Omaha, NE, 68198-6245, USA. doleynik@unmc.edu.
authors.forename: Dmitry
authors.initials: D
authors.lastname: Oleynikov
mesh_terms: D000713:Anastomosis, Roux-en-Y; D050110:Bariatric Surgery / Q000379:methods; D001471:Barrett Esophagus / Q000150:complications / Q000601:surgery*; D005764:Gastroesophageal Reflux / Q000209:etiology / Q000601:surgery*; D006551:Hernia, Hiatal / Q000209:etiology / Q000601:surgery; D006801:Humans; D009767:Obesity, Morbid / Q000150:complications / Q000601:surgery*
keywords: Bariatric surgery; Barrett’s esophagus; GERD; Obesity; Reflux