title: The effect of colostrum ingestion during the first 24 hours of life on early postnatal development of piglet immune systems.
abstract: It has been suggested that colostrum is important not only for direct protection from pathogens but also for proper development of immune systems in piglets. In this study, we focused on the effect of colostrum ingestion during the first 24 h of life on early postnatal development of piglet immune systems. Thirty-six piglets from five litters were divided into colostrum-fed (CoF) and colostrum-deprived (CoD) groups. The former group was allowed to suckle normally while formula milk was fed to the latter group during the first 24 h of life. At the weaning period, the concentrations of fecal immunoglobulin (Ig) A and plasma IgG as well as the number of blood leukocyte subsets were analyzed. Fecal IgA and plasma IgG concentrations in the CoF group were more than twice as high as those in the CoD group (P < 0.01). In addition, the number of blood B cells was significantly higher in the CoF group than that in the CoD group (P < 0.05). This study demonstrates that colostrum ingestion during the first 24 h plays a significant role in early postnatal development of both mucosal and systemic immunity of piglets.
authors.affiliation: Laboratory of Animal Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.
authors.forename: Shohei
authors.initials: S
authors.lastname: Ogawa
authors.affiliation: Laboratory of Animal Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.|Kyoto Institute of Nutrition & Pathology, Ujitawara, Tsuzuki, Kyoto, Japan.
authors.forename: Takamitsu
authors.initials: T
authors.lastname: Tsukahara
authors.affiliation: KYODOKEN Institute, Shimoitabashi, Fushimi, Kyoto, Japan.
authors.forename: Taishi
authors.initials: T
authors.lastname: Imaoka
authors.affiliation: KYODOKEN Institute, Shimoitabashi, Fushimi, Kyoto, Japan.
authors.forename: Nobuo
authors.initials: N
authors.lastname: Nakanishi
authors.affiliation: Laboratory of Animal Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.
authors.forename: Kazunari
authors.initials: K
authors.lastname: Ushida
authors.affiliation: Laboratory of Animal Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University, Kyoto, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Inoue
mesh_terms: D000818:Animals; D000831:Animals, Newborn / Q000254:growth & development* / Q000276:immunology*; D003126:Colostrum / Q000276:immunology* / Q000502:physiology*; D005243:Feces / Q000737:chemistry; D005260:Female; D007107:Immune System / Q000254:growth & development* / Q000276:immunology*; D007070:Immunoglobulin A / Q000032:analysis; D007074:Immunoglobulin G / Q000097:blood; D018655:Lymphocyte Count; D016131:Lymphocyte Subsets / Q000276:immunology; D008297:Male; D011247:Pregnancy; D013552:Swine / Q000254:growth & development* / Q000276:immunology*; D013997:Time Factors; D014886:Weaning
chemical_list: D007070:Immunoglobulin A; D007074:Immunoglobulin G
keywords: B cell; colostrum; early postnatal development; immunoglobulins; pig