title: A General and Selective Rhodium-Catalyzed Reduction of Amides, N-Acyl Amino Esters, and Dipeptides Using Phenylsilane.
abstract: This article describes a selective reduction of functionalized amides, including N-acyl amino esters and dipeptides, to the corresponding amines using simple [Rh(acac)(cod)]. The catalyst shows excellent chemoselectivity in the presence of different sensitive functional moieties.
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der, Universität Rostock, Albert Einstein Str. 29a, 18059, Rostock, Germany.
authors.forename: Shoubhik
authors.initials: S
authors.lastname: Das
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der, Universität Rostock, Albert Einstein Str. 29a, 18059, Rostock, Germany.
authors.forename: Yuehui
authors.initials: Y
authors.lastname: Li
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der, Universität Rostock, Albert Einstein Str. 29a, 18059, Rostock, Germany.
authors.forename: Liang-Qiu
authors.initials: LQ
authors.lastname: Lu
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der, Universität Rostock, Albert Einstein Str. 29a, 18059, Rostock, Germany.
authors.forename: Kathrin
authors.initials: K
authors.lastname: Junge
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der, Universität Rostock, Albert Einstein Str. 29a, 18059, Rostock, Germany. Matthias.beller@catalysis.de.
authors.forename: Matthias
authors.identifier: 0000-0001-5709-0965
authors.initials: M
authors.lastname: Beller
mesh_terms: D000577:Amides / Q000737:chemistry*; D000588:Amines / Q000737:chemistry*; D002384:Catalysis; D004151:Dipeptides / Q000737:chemistry*; D004952:Esters / Q000737:chemistry; D010084:Oxidation-Reduction; D012238:Rhodium / Q000737:chemistry*; D012821:Silanes / Q000737:chemistry*
chemical_list: D000577:Amides; D000588:Amines; D004151:Dipeptides; D004952:Esters; D012821:Silanes; D012238:Rhodium
keywords: amides; esters; hydrosilylation; peptides; rhodium