title: Highly selective and sensitive fluorescent probe for the detection of nitrite.
abstract: A simple and reliable fluorescent nitrite (NO2(-)) probe, 2-(1H-phenanthro[9,10-d] imidazol-2-yl)aniline (PA), was rationally developed based on a novel NO2(-)-mediated diazozation and subsequent cyclization. The new sensing mechanism of the probe was confirmed by using NMR, IR spectra, control experiments and DFT calculations. The synthesized probe showed low pH dependence, fast and highly selective fluorescence response to NO2(-) over other species. Under the optimized conditions, the linear response of the probe toward NO2(-) was in the range of 0.1-10 μM with a low detection limit of 4.3×10(-8) M. Moreover, PA was successfully applied for the determination of NO2(-) in environmental samples and food products.
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Biao
authors.initials: B
authors.lastname: Gu
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Liyan
authors.initials: L
authors.lastname: Huang
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Jiali
authors.initials: J
authors.lastname: Hu
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Jingjing
authors.initials: J
authors.lastname: Liu
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Su
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Duan
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China. Electronic address: hatiao-li@hunnu.edu.cn.
authors.forename: Haitao
authors.initials: H
authors.lastname: Li
authors.affiliation: Key Laboratory of Chemical Biology and Traditional Chinese Medicine Research (Ministry of Education), College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha 410081, China.
authors.forename: Shouzhuo
authors.initials: S
authors.lastname: Yao
mesh_terms: D000814:Aniline Compounds / Q000138:chemical synthesis / Q000737:chemistry*; D004579:Electron Transport; D005456:Fluorescent Dyes / Q000138:chemical synthesis / Q000737:chemistry*; D005504:Food Analysis; D006863:Hydrogen-Ion Concentration; D057230:Limit of Detection; D008958:Models, Molecular; D008968:Molecular Conformation; D009573:Nitrites / Q000032:analysis* / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry; D013050:Spectrometry, Fluorescence; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D000814:Aniline Compounds; D005456:Fluorescent Dyes; D009573:Nitrites; D012997:Solvents; D014867:Water; C023650:aniline
keywords: Fluorescent probe; Highly selective response; Nitrite