title: High-density lipoprotein cholesterol on a roller coaster: where will the ride end?
abstract: Bowe et al. report an association between low high-density lipoprotein cholesterol concentrations and various incident chronic kidney disease end points in a cohort of almost 2 million US veterans followed for 9 years. These impressive data should be a starting point for further investigations including genetic epidemiologic investigations as well as post hoc analyses of interventional trials that target high-density lipoprotein cholesterol and, finally, studies that focus on the functionality of high-density lipoprotein particles.
authors.affiliation: Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, Austria. Electronic address: Florian.Kronenberg@i-med.ac.at.
authors.forename: Florian
authors.initials: F
authors.lastname: Kronenberg
mesh_terms: D002784:Cholesterol; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D006801:Humans; D008075:Lipoproteins, HDL
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D008075:Lipoproteins, HDL; D002784:Cholesterol