title: Data on in vitro and in vivo cell orientation on substrates with different topographies.
abstract: This data article contains data related to the research article entitled "Substrate topography: A valuable in vitro tool, but a clinical red herring for in vivo tenogenesis" [1]. We report measurements on tenocyte viability, metabolic activity and proliferation on substrates with different topographies. We also report the effect of substrates with different topographies on host cells in a subcutaneous model.
authors.affiliation: Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), Biosciences Research Building (BRB), National University of Ireland Galway, NUI Galway, Galway, Ireland; Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
authors.forename: Andrew
authors.initials: A
authors.lastname: English
authors.affiliation: Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), Biosciences Research Building (BRB), National University of Ireland Galway, NUI Galway, Galway, Ireland; Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
authors.forename: Ayesha
authors.initials: A
authors.lastname: Azeem
authors.affiliation: Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), Biosciences Research Building (BRB), National University of Ireland Galway, NUI Galway, Galway, Ireland; Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
authors.forename: Kyriakos
authors.initials: K
authors.lastname: Spanoudes
authors.affiliation: School of Biological Sciences, University of East Anglia, Norwich, UK.
authors.forename: Eleanor
authors.initials: E
authors.lastname: Jones
authors.affiliation: Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin, Ireland.
authors.forename: Bhawana
authors.initials: B
authors.lastname: Tripathi
authors.affiliation: Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin, Ireland.
authors.forename: Nandita
authors.initials: N
authors.lastname: Basu
authors.affiliation: Materials and Surface Science Institute (MSSI), Department of Physics and Energy, University of Limerick, Limerick, Ireland.
authors.forename: Karrina
authors.initials: K
authors.lastname: McNamara
authors.affiliation: Materials and Surface Science Institute (MSSI), Department of Physics and Energy, University of Limerick, Limerick, Ireland.
authors.forename: Syed A M
authors.initials: SA
authors.lastname: Tofail
authors.affiliation: Proxy Biomedical, Galway, Ireland.
authors.forename: Niall
authors.initials: N
authors.lastname: Rooney
authors.affiliation: School of Biological Sciences, University of East Anglia, Norwich, UK.
authors.forename: Graham
authors.initials: G
authors.lastname: Riley
authors.affiliation: Tyndall National Institute, Cork, Ireland.
authors.forename: Alan
authors.initials: A
authors.lastname: O'Riordan
authors.affiliation: Centre for Research on Adaptive Nanostructures and Nanodevices (CRANN), Trinity College Dublin, Dublin, Ireland.
authors.forename: Graham
authors.initials: G
authors.lastname: Cross
authors.affiliation: Institute of Health & Biomedical Innovation, Queensland University of Technology, Australia.
authors.forename: Dietmar
authors.initials: D
authors.lastname: Hutmacher
authors.affiliation: Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
authors.forename: Manus
authors.initials: M
authors.lastname: Biggs
authors.affiliation: Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
authors.forename: Abhay
authors.initials: A
authors.lastname: Pandit
authors.affiliation: Regenerative, Modular & Developmental Engineering Laboratory (REMODEL), Biosciences Research Building (BRB), National University of Ireland Galway, NUI Galway, Galway, Ireland; Network of Excellence for Functional Biomaterials (NFB), BRB, NUI Galway, Galway, Ireland; Centre for Research in Medical Devices (CÚRAM), BRB, NUI Galway, Galway, Ireland.
authors.forename: Dimitrios I
authors.initials: DI
authors.lastname: Zeugolis
keywords: Anisotropic substrates; Imprinting; Subcutaneous model; Tenocytes