title: Concomitant pemphigus vulgaris and pemphigoid gestationis: a case report and review of the literature.
abstract: Pemphigus and pemphigoid are two unique acquired immunobullous diseases with distinct clinical presentations, histological findings, and characteristic serology; they are rarely reported to coexist in the same patient. Herein we present a 29-year-old woman with a history of pemphigus vulgaris, diagnosed by histology and positive desmoglein-3 antibodies on ELISA. She presented to our clinic shortly after the delivery of her first child with tense vesicles and bullae on an erythematous base on her abdomen. Biopsy was consistent with pemphigoid gestationis and direct immunofluorescence confirmed the diagnosis. To our knowledge, there are no other reported cases of pemphigoid gestationis occurring in a patient with pemphigus vulgaris.
authors.affiliation: Baylor College of Medicine. harina.vin@gmail.com.
authors.forename: Harina
authors.initials: H
authors.lastname: Vin
authors.forename: Sarah J
authors.initials: SJ
authors.lastname: Seyfer
authors.forename: Colt M
authors.initials: CM
authors.lastname: McClain
authors.forename: Sylvia
authors.initials: S
authors.lastname: Hsu
mesh_terms: D000328:Adult; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D006559:Pemphigoid Gestationis / Q000175:diagnosis*; D010391:Pemphigoid, Bullous / Q000175:diagnosis*; D011247:Pregnancy; D012867:Skin / Q000000981:diagnostic imaging*