title: Urodynamic outcomes of detethering in children: experience with 46 pediatric patients.
abstract: OBJECTIVE
  Tethered cord syndrome (TCS) manifests with neurological and urological complaints. Surgical detethering is the main treatment for TCS. Children with urological symptoms are required objective pre- and postoperative evaluations in order to predict urological outcome. The aims of this study are to investigate the effects of detethering procedure on the urodynamic tests and to determine the relationship between the changes of urodynamic tests and the patients' age and gender.
  
  
  METHODS
  The data of urodynamic tests in 46 pediatric patients, who underwent surgery for TCS, were retrospectively evaluated. Bladder capacity, post-voiding residual urine volume, maximum intravesical pressure, and bladder compliance of each patient were measured in preoperative period and at the third month after surgery. These parameters were statistically compared, and the correlations of these parameters with age, gender, and etiology of the TCS were also investigated.
  
  
  RESULTS
  Bladder capacity and post-voiding residual urine volume were decreased and maximum intravesical pressure and bladder compliance were increased after surgery for TCS. The decrease in bladder capacity was significant in patients older than 10 years (p < 0.05). The increase in maximum intravesical pressure was also positively correlated with age (p < 0.05). But the increase in bladder compliance was negatively correlated with age (p < 0.05).
  
  
  CONCLUSIONS
  Bladder capacity, post-voiding residual urine volume, and bladder compliance are mainly affected by surgery in patients with TCS. From the urological viewpoint, children older than 10 years are most likely to benefit from surgery for TCS.
authors.affiliation: Department of Neurosurgery, Gaziantep University, Gaziantep, Turkey. drmuratgeyik@gmail.com.
authors.forename: Murat
authors.initials: M
authors.lastname: Geyik
authors.affiliation: Department of Neurology, Gaziantep University, Gaziantep, Turkey.
authors.forename: Sırma
authors.initials: S
authors.lastname: Geyik
authors.affiliation: Department of Urology, Gaziantep University, Gaziantep, Turkey.
authors.forename: Haluk
authors.initials: H
authors.lastname: Şen
authors.affiliation: Department of Neurosurgery, Etimesgut Military Hospital, Ankara, Turkey.
authors.forename: Serhat
authors.initials: S
authors.lastname: Pusat
authors.affiliation: Department of Neurosurgery, Gaziantep University, Gaziantep, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Alptekin
authors.affiliation: Department of Urology, Gaziantep University, Gaziantep, Turkey.
authors.forename: Ali Erdem
authors.initials: AE
authors.lastname: Yılmaz
authors.affiliation: Department of Neurosurgery, Gaziantep University, Gaziantep, Turkey.
authors.forename: Mert
authors.initials: M
authors.lastname: Nazik
authors.affiliation: Department of Neurosurgery, Gaziantep University, Gaziantep, Turkey.
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Erkutlu
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007674:Kidney Diseases / Q000209:etiology* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D009436:Neural Tube Defects / Q000000981:diagnostic imaging / Q000601:surgery*; D019635:Neurosurgical Procedures / Q000379:methods*; D012189:Retrospective Studies; D016896:Treatment Outcome; D001743:Urinary Bladder / Q000502:physiology; D014563:Urodynamics / Q000502:physiology*
keywords: Children; Surgery; Tethered cord syndrome; Urodynamic test