title: Mortality due to acute adverse drug reactions in Galicia: 1997-2011.
abstract: The aim of this research is to study all people who died in the Autonomous Community of Galicia from acute death after drugconsumption (ADR) in which there was judicial intervention during the period from 1997 to 2011, according to inclusion and exclusión criteria established by the National Drug Plan for the entire national territory. Sociodemographic and clinical characteristics of deceased subjects were studied, in order to identify key risk factors and/or vulnerable populations.A total of 805 deaths were recorded. The distribution by provinces and municipalities corresponds to the areas of greatest population, incidence of consumption and proximity to the coast. The average age of these patients was 34.34 years, with a gradual increase over years. Most of them were male (91.2%) and single (47.7). 43.5% of the deceased habitually used the parenteral route of administration and 36.4% had positive HIV serology. The most frequently-detected substances corresponded to opiates (heroin: 61.3%, methadone: 35.6%), followed by cocaine (53.7%), although the most common pattern was that of poly-consumption. ADR mortality figures remain relatively stable throughout the study period. The predominant pattern is that of males, opiates and a long history of consumption.
authors.affiliation: Complexo Hospitalario Universitario A Coruña (CHUAC). SERGAS.. Domingo.Miguel.Arias@sergas.es.
authors.forename: Domingo
authors.initials: D
authors.lastname: Miguel-Arias
authors.forename: César
authors.initials: C
authors.lastname: Pereiro Gómez
authors.forename: Ana M
authors.initials: AM
authors.lastname: Bermejo Barrera
authors.forename: Benito
authors.initials: B
authors.lastname: López de Abajo Rodríguez
authors.forename: María
authors.initials: M
authors.lastname: Sobrido Prieto
mesh_terms: D000293:Adolescent; D000328:Adult; D002423:Cause of Death; D062787:Drug Overdose / Q000401:mortality*; D064420:Drug-Related Side Effects and Adverse Reactions / Q000401:mortality*; D005260:Female; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D013997:Time Factors; D055815:Young Adult