title: REGENERATIVE ENGINEERING: APPROACHES TO LIMB REGENERATION AND OTHER GRAND CHALLENGES.
abstract: The clinical grand challenge to regenerate complex tissue and organ systems call for a paradigm shift that requires a transdisciplinary approach. The field of regenerative engineering puts forward a Convergence approach to create a regenerative toolbox to move beyond individual tissue repair to the regeneration of complex tissues and organ systems. Here we discuss the regenerative tool box currently under development to address grand opportunities in complex tissue/organ regeneration.
authors.affiliation: Department of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA; Department of Chemical and Biomolecular Engineering University of Connecticut, Storrs, CT 06269, USA.
authors.forename: Cato T
authors.initials: CT
authors.lastname: Laurencin
authors.affiliation: Department of Orthopaedic Surgery; Institute for Regenerative Engineering; Raymond and Beverly Sackler Center for Biomedical, Biological, Physical and Engineering Sciences; University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Biomedical Engineering; Department of Materials Science and Engineering, Storrs, CT 06269, USA.
authors.forename: Lakshmi S
authors.initials: LS
authors.lastname: Nair