title: [Management of soft tissues sarcoma of the limbs by external beam radiation therapy].
abstract: Soft tissue sarcomas are rare tumours. Conservative surgery followed by postoperative radiation therapy represents the gold standard in the majority of cases. Postoperative radiotherapy improves local control without affecting survival. Besides the quality of surgical excision, which remains the major prognostic factor, the importance of the irradiation volume and particularly margins used in external beam radiotherapy were also found to influence local control of the disease. In this study, we propose to conduct a literature review on the present state of our knowledge on this subject in the form of an articulated controversy: in favour or opposed to large margins in external radiotherapy.
authors.affiliation: Département de radiothérapie, institut Paoli-Calmettes, 232, boulevard Sainte-Marguerite, 13009 Marseille, France. Electronic address: moureaul@ipc.unicancer.fr.
authors.forename: L
authors.initials: L
authors.lastname: Moureau-Zabotto
authors.affiliation: Département de radiothérapie, institut Claudius-Regaud, 1, avenue Irène-Joliot-Curie, IUCT O, 31059 Toulouse, France.
authors.forename: M
authors.initials: M
authors.lastname: Delannes
authors.affiliation: Département de radiothérapie, institut Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif, France.
authors.forename: C
authors.initials: C
authors.lastname: Le Péchoux
authors.affiliation: Centre Léon-Bérard, 28, rue Laennec, 69008 Lyon, France.
authors.forename: M P
authors.initials: MP
authors.lastname: Sunyach
authors.affiliation: Institut Bergonié, 229, cours de l'Argonne, 33000 Bordeaux, France.
authors.forename: G
authors.initials: G
authors.lastname: Kantor
authors.affiliation: Institut Bergonié, 229, cours de l'Argonne, 33000 Bordeaux, France.
authors.forename: P
authors.initials: P
authors.lastname: Sargos
authors.affiliation: Département de radiothérapie, centre Antoine-Lacassagne, 133, avenue de Valombrose, 06189 Nice, France.
authors.forename: J
authors.initials: J
authors.lastname: Thariat
authors.affiliation: Centre Val d'Aurelle, parc Euromédecine, 208, rue des Apothicaires, 34298 Montpellier, France.
authors.forename: C
authors.initials: C
authors.lastname: Llacer-Moscardo
mesh_terms: D005121:Extremities; D006801:Humans; D009364:Neoplasm Recurrence, Local; D011879:Radiotherapy Dosage; D018714:Radiotherapy, Adjuvant; D012509:Sarcoma / Q000628:therapy*; D012983:Soft Tissue Neoplasms / Q000628:therapy*
keywords: External beam radiotherapy volume; Limbs; Membres; Sarcomes tissus mous; Soft tissue sarcoma; Volume d’irradiation