title: Sepsis management: An evidence-based approach.
abstract: The Surviving Sepsis Campaign (SSC) guidelines have outlined an early goal directed therapy (EGDT) which demonstrates a standardized approach to ensure prompt and effective management of sepsis. Having said that, there are barriers associated with the application of evidence-based practice, which often lead to an overall poorer adherence to guidelines. Considering the global burden of disease, data from low- to middle-income countries is scarce. Asia is the largest continent but most Asian countries do not have a well-developed healthcare system and compliance rates to resuscitation and management bundles are as low as 7.6% and 3.5%, respectively. Intensive care units are not adequately equipped and financial concerns limit implementation of expensive treatment strategies. Healthcare policy-makers should be notified in order to alleviate financial restrictions and ensure delivery of standard care to septic patients.
authors.affiliation: Postgraduate Year IV, Department of Emergency Medicine, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Muhammad Akbar
authors.initials: MA
authors.lastname: Baig
authors.affiliation: Section of Pulmonology & Critical Care Services, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Hira
authors.initials: H
authors.lastname: Shahzad
authors.affiliation: Section of Adult Infectious Diseases, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.. ).
authors.forename: Bushra
authors.initials: B
authors.lastname: Jamil
authors.affiliation: Adult Critical Care Services, Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Erfan
authors.initials: E
authors.lastname: Hussain
mesh_terms: D001208:Asia; D002985:Clinical Protocols; D019468:Disease Management; D019317:Evidence-Based Medicine; D019983:Guideline Adherence; D006801:Humans; D007362:Intensive Care Units; D064872:Patient Care Bundles / Q000379:methods*; D017410:Practice Guidelines as Topic; D012151:Resuscitation; D018805:Sepsis / Q000628:therapy*
keywords: Sepsis in Asia, Early Goal Directed therapy (EGDT), Sepsis resuscitation bundle, Sepsis management bundle.