title: Cutaneous invasion from sarcomatoid urothelial carcinoma: clinical and dermatopathologic features.
abstract: In Brazil, without considering the non-melanoma skin tumors, bladder cancer in men is the eighth most common, and the urothelial carcinoma or transitional cell carcinoma is the most common among these. Cutaneous metastases from urothelial neoplasms appear as single or multiple erythematous, infiltrated nodules or plaques, and like other cases of distant disease, it is indicative of poor prognosis. The invasive urothelial carcinoma is recognized for its ability to present divergent differentiation and morphological variants. The sarcomatoid urothelial carcinoma is a rare cancer that consists of two different components: one composed of epithelial tissue and the other with sarcomatoid features of mesenchymal origin. The authors describe a case of cutaneous metastasis of sarcomatoid urothelial carcinoma in a 63-year-old male patient.
authors.affiliation: Instituto de Dermatologia Professor Rubem David Azulay, Santa Casa de Misericórdia do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Fred
authors.initials: F
authors.lastname: Bernardes Filho
authors.affiliation: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors.forename: Alessandro Severo Alves
authors.initials: AS
authors.lastname: de Melo
authors.affiliation: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors.forename: Andréa Rodriguez Cordovil
authors.initials: AR
authors.lastname: Pires
authors.affiliation: Universidade Federal do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Omar
authors.initials: O
authors.lastname: Lupi
authors.affiliation: Universidade Federal Fluminense, Niterói, RJ, Brazil.
authors.forename: Daniel Gama
authors.initials: DG
authors.lastname: das Neves
authors.affiliation: Hospital Orêncio de Freitas, Niterói, RJ, Brazil.
authors.forename: Margareth Fernandes
authors.initials: MF
authors.lastname: da Cruz
authors.affiliation: Rio de Janeiro, Rio de Janeiro, RJ, Brazil.
authors.forename: Bernard Kawa
authors.initials: BK
authors.lastname: Kac
mesh_terms: D002295:Carcinoma, Transitional Cell / Q000473:pathology*; D002296:Carcinosarcoma / Q000473:pathology*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D012867:Skin / Q000473:pathology; D012878:Skin Neoplasms / Q000473:pathology*; D001749:Urinary Bladder Neoplasms / Q000473:pathology*; D019459:Urothelium / Q000473:pathology