title: [Influence of smoking cessation on the microcirculatory bed in apparently healthy young people].
abstract: OBJECTIVE
  To study the influence of smoking cessation on the microcirculatory bed (MCB) in 33 healthy young people.
  
  
  METHODS
  The investigation enrolled 33 healthy young people (male/female (M/F) ratio, 20:13; mean age, 21.6±0.5 years) who had quit smoking 1 month to 10 years (mean age 2.5±0.5 years) before. Comparable groups consisted of 15 smokers (M/F ratio, 5:10; mean age, 21.5±0.8 years) and 18 nonsmokers (M/F ratio, 6:12; mean age, 21±0.3 years). Computer-assisted video-biomicroscopy of the bulbar conjunctiva was carried out. When assessing the
  
  
  RESULTS
  attention was focused on microvessel diameter changes in the patients who had quit smoking compared to the smokers and nonsmokers.
  
  
  RESULTS
  As compared to the smokers, those who had quit smoking showed a significant increase in the mean diameters of arterioles (13.01±0.41 and 18.33±0.65 µm; р<0.001) and capillaries (9.2±0.23 and 9.89±0.19 µm; р<0.05). The number of functioning capillaries per mm2 of the conjunctival surface did not differ from that in the nonsmokers (8.01±0.21 and 8.25±0.44; р>0.05). Thus, the rarefication phenomenon reflecting the influence of smoking on the MCB vessels at a young age undergoes rapidly regression. There are increases in the diameter of arterioles and the number of functioning capillaries just in the first months of smoking cessation (р<0.01).
  
  
  CONCLUSIONS
  The considerably increased diameters of arterioles and capillaries and the larger number of functioning capillaries per mm2 of the conjunctival surface suggest that smoking cessation at a young age have a positive impact on MCB vessels.
authors.affiliation: Far Eastern State Medical University, Ministry of Health of Russia, Khabarovsk, Russia.
authors.forename: B Z
authors.initials: BZ
authors.lastname: Sirotin
authors.affiliation: Far Eastern State Medical University, Ministry of Health of Russia, Khabarovsk, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Korneeva
mesh_terms: D003228:Conjunctiva / Q000098:blood supply*; D005260:Female; D006801:Humans; D008297:Male; D008833:Microcirculation; D020678:Microscopic Angioscopy / Q000379:methods; D055806:Microvessels / Q000033:anatomy & histology / Q000473:pathology / Q000503:physiopathology; D016540:Smoking Cessation; D055815:Young Adult