title: Genetic variations (Arg5Pro and Leu6Pro) modulate the structure and activity of GPX1 and genetic risk for vitiligo.
authors.affiliation: Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
authors.forename: Mohmmad Shoab
authors.initials: MS
authors.lastname: Mansuri
authors.affiliation: Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
authors.forename: Naresh C
authors.initials: NC
authors.lastname: Laddha
authors.affiliation: Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
authors.forename: Mitesh
authors.initials: M
authors.lastname: Dwivedi
authors.affiliation: Department of Bioinformatics & Structural Biology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
authors.forename: Dhaval
authors.initials: D
authors.lastname: Patel
authors.affiliation: Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
authors.forename: Tina
authors.initials: T
authors.lastname: Alex
authors.affiliation: Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
authors.forename: Mala
authors.initials: M
authors.lastname: Singh
authors.affiliation: Department of Bioinformatics & Structural Biology, Indian Institute of Advanced Research, Gandhinagar, Gujarat, India.
authors.forename: Desh D
authors.initials: DD
authors.lastname: Singh
authors.affiliation: Department of Biochemistry, Faculty of Science, The Maharaja Sayajirao University of Baroda, Vadodara, Gujarat, India.
authors.forename: Rasheedunnisa
authors.initials: R
authors.lastname: Begum
mesh_terms: D019943:Amino Acid Substitution; D016022:Case-Control Studies; D004912:Erythrocytes / Q000201:enzymology; D005260:Female; D056726:Genetic Association Studies; D020022:Genetic Predisposition to Disease; D005979:Glutathione Peroxidase / Q000235:genetics*; D006801:Humans; D015810:Linkage Disequilibrium; D015227:Lipid Peroxidation; D008297:Male; D056004:Molecular Dynamics Simulation; D014820:Vitiligo / Q000235:genetics*; D000094765:Glutathione Peroxidase GPX1
chemical_list: D005979:Glutathione Peroxidase; D000094765:Glutathione Peroxidase GPX1; C000722067:GPX1 protein, human
keywords: glutathione peroxidase; lipid peroxidation; molecular dynamics simulation; oxidative stress; vitiligo