title: Practice of the Treatment of Milk Allergy  in the UK: A National Audit.
abstract: BACKGROUND
  The management of cow's milk allergy (CMA) includes initial dairy exclusion with suitable dietary substitution, diagnostic challenges where indicated, and supervised re-introduction as the condition resolves. Information on clinician practice is limited. We audited the current practice of clinicians in the UK to evaluate adherence to international guidelines.
  
  
  METHODS
  An online questionnaire was sent to all clinicians whose practice included children identified on the national allergy society website. One hundred and sixty questionnaires were sent and 116 (73%) responded.
  
  
  RESULTS
  Skin prick tests were more commonly used than serum-specific IgE as diagnostic tests. Respective proportions selecting amino acid formulas (AAF) or extensively hydrolysed formulas (EHF) in severe versus mild/moderate presentations were 78 and 40% versus 20 and 88%; soya formula was the first choice in 8.6 and 24%. The criteria for selection of AAF as the first choice were predominantly severe IgE-mediated and non-IgE-mediated reactions, failure to thrive and if infants refused EHF. Oral challenges might be used to diagnose CMA in 69%, whereas nearly 90% performed challenges to assess tolerance. Most of these were open challenges, more commonly with fresh milk (90%) than baked milk (60%). Home baked milk challenges were frequently considered (70%), although only after consideration of the clinical scenario. Practice did not vary with experience.
  
  
  CONCLUSIONS
  Current practice amongst UK clinicians of the management of CMA is broadly in line with current guidance, particularly the positioning of hypoallergenic milks as substitute milk choices. A notable deviation was the use of home baked milk challenges or re-introduction.
authors.forename: David
authors.initials: D
authors.lastname: Luyt
authors.forename: M Thirumala
authors.initials: MT
authors.lastname: Krishnan
authors.forename: Pia
authors.initials: P
authors.lastname: Huber
authors.forename: Andrew
authors.initials: A
authors.lastname: Clark
mesh_terms: D006801:Humans; D008485:Medical Audit; D016269:Milk Hypersensitivity / Q000175:diagnosis / Q000628:therapy*; D006113:United Kingdom