title: [Survival rate after D3-lymphadenectomy for right-sided colic cancer: case-match study].
abstract: The aim of the study was to compare the effectiveness of D3-lymphadenectomy in compliance with «no-touch» principle and mesocolectomy with traditional hemicolectomy in patients with right-sided colon cancer.
  
  
  METHODS
  It is retrospective-prospective comparative case-match study. From prospectively collected database patients with right-sided colon cancer stage I-III treated in 2009-2013 without adjuvant chemotherapy were selected. Patients who underwent conventional right-sided hemicolectomy with D2-lymphadenectomy in the regional oncologic dispensary formed the first group. The second group included patients after right-sided hemicolectomy with D3-lymphadenectomy, «no-touch» principle and mesocolectomy performed in academic hospital of the third level. From both groups 'case-match' patients by gender, age, stage and location of primary tumor were selected. Each group consisted of 50 patients.
  
  
  RESULTS
  Overall and cancer-related 5-year survival was significantly higher in the second group - 80.9% vs. 56.0% (p=0.01) and 93.4% vs. 59.8% (p=0.01), respectively.
  
  
  CONCLUSIONS
  D3-lymphadenectomy and mesocolectomy for right-sided colon cancer stage I-III without adjuvant chemotherapy provides significantly better overall and cancer-related 5-year survival compared with conventional right-sided hemicolectomy. Thus, D3-lymphadenectomy and mesocolectomy in compliance with «no-touch» principle for right-sided colon cancer is reproducible and effective in Russian conditions.
authors.affiliation: Chair of Coloproctology and Endoscopic Surgery, I.M. Sechenov First Moscow State Medical University.
authors.forename: P V
authors.initials: PV
authors.lastname: Tsar'kov
authors.affiliation: Chair of Coloproctology and Endoscopic Surgery, I.M. Sechenov First Moscow State Medical University.
authors.forename: S K
authors.initials: SK
authors.lastname: Efetov
authors.affiliation: Chair of Coloproctology and Endoscopic Surgery, I.M. Sechenov First Moscow State Medical University.
authors.forename: I A
authors.initials: IA
authors.lastname: Tulina
authors.affiliation: Chair of Coloproctology and Endoscopic Surgery, I.M. Sechenov First Moscow State Medical University.
authors.forename: A Yu
authors.initials: AY
authors.lastname: Kravchenko
authors.affiliation: Department of Pathological Anatomy, acad. B.V. Petrovsky Russian Research Center of Surgery of RAS, Moscow.
authors.forename: D N
authors.initials: DN
authors.lastname: Fedorov
authors.affiliation: Department of Abdominal Oncology, V.M. Efetov Clinical Oncology Dispensary, Simferopol, Republic of Crimea.
authors.forename: S V
authors.initials: SV
authors.lastname: Efetov
mesh_terms: D034841:Abdominal Cavity; D003082:Colectomy / Q000379:methods; D003110:Colonic Neoplasms / Q000401:mortality / Q000556:secondary / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008197:Lymph Node Excision / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012189:Retrospective Studies; D012426:Russia / Q000453:epidemiology; D015996:Survival Rate / Q000639:trends