title: [COMPARATIVE EVALUATION OF CURRENT METHODS OF ANESTHESIA IN PERFORMANCE OF TRANSRECTAL PROSTATE BIOPSY].
abstract: Prostate biopsy guided by transrectal ultrasonography (TRUS) is largely used in prostate cancer diagnostics. This procedure is usually quite painful and fear of pain could scare patients from this important research. The aim of the study was to compare methods of anesthesia for prostate biopsy. The patients were divided into 4 groups (40 patients in each group). TRUS-guided periprostatic anesthesia with 1% solution of lidocaine (10 ml) was carried out in the first group. An intrarectal introduction of 5 g EMLA cream (lidocaine 2,5% and prilocaine 2,5%) was applied in the second group. The intrarectal introduction of 10% lidocaine spray (3 doses) was used in the third group. Placebo as ultrasonic gel was utilized for the fourth group. The authors used the 100-score linear visual analog scale (LVS 1-100) and 5-score numeric visual scale (NVS-4). Minimal scores of pain were obtained in patients using TRUS-guided periprostatic anesthesia with 1% solution of lidocaine (10 ml). This type of anesthesia didn't lead to increase of the number of complications.
authors.forename: M E
authors.initials: ME
authors.lastname: Topuzov
authors.forename: A E
authors.initials: AE
authors.lastname: Pryalukhin
authors.forename: I O
authors.initials: IO
authors.lastname: Belogortsev
authors.forename: V A
authors.initials: VA
authors.lastname: Zubarev
authors.forename: S S
authors.initials: SS
authors.lastname: Vodop'yan
mesh_terms: D000285:Administration, Rectal; D000368:Aged; D000698:Analgesia / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000493:pharmacokinetics; D004304:Dosage Forms; D006801:Humans; D061705:Image-Guided Biopsy / Q000009:adverse effects / Q000379:methods; D008012:Lidocaine / Q000008:administration & dosage / Q000493:pharmacokinetics; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D010146:Pain / Q000209:etiology / Q000517:prevention & control; D011467:Prostate / Q000473:pathology; D011471:Prostatic Neoplasms / Q000473:pathology*; D018084:Ultrasonography, Interventional / Q000009:adverse effects / Q000379:methods; D064232:Visual Analog Scale
chemical_list: D000779:Anesthetics, Local; D004304:Dosage Forms; D008012:Lidocaine