title: Asymptomatic pontine and extra-pontine lesions in a patient with end-stage renal disease.
abstract: Osmotic demyelination syndrome leading to central pontine/extra-pontine myelinolysis (CPM/EPM) occurs mainly in patients with history of alcohol abuse, malnourishment, following liver transplantation and less commonly, in association with other systemic diseases. Asymptomatic CPM/EPM is rare. Patients with end-stage renal disease (ESRD) who develop CPM/EPM are usually symptomatic with florid neurologic manifestations. Herein, we present a patient with ESRD on maintenance hemodialysis who was incidentally detected to have pontine and extra-pontine lesions suggestive of myelinolysis without any neurologic signs or symptoms.
authors.forename: Raj Kanwar
authors.initials: RK
authors.lastname: Yadav
authors.forename: Chandan J
authors.initials: CJ
authors.lastname: Das
authors.affiliation: Department of Nephrology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Soumita
authors.initials: S
authors.lastname: Bagchi
authors.forename: Sanjay
authors.initials: S
authors.lastname: Agarwal
mesh_terms: D000328:Adult; D058070:Asymptomatic Diseases; D006801:Humans; D033162:Incidental Findings; D007676:Kidney Failure, Chronic / Q000175:diagnosis / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D017590:Myelinolysis, Central Pontine / Q000175:diagnosis / Q000209:etiology*; D006435:Renal Dialysis / Q000009:adverse effects*; D012307:Risk Factors