title: Three-dimensional MR Cholangiopancreatography in a Breath Hold with Sparsity-based Reconstruction of Highly Undersampled Data.
abstract: Purpose To develop a three-dimensional breath-hold (BH) magnetic resonance (MR) cholangiopancreatographic protocol with sampling perfection with application-optimized contrast using different flip-angle evolutions (SPACE) acquisition and sparsity-based iterative reconstruction (SPARSE) of prospectively sampled 5% k-space data and to compare the results with conventional respiratory-triggered (RT) acquisition. Materials and Methods This HIPAA-compliant prospective study was institutional review board approved. Twenty-nine patients underwent conventional RT SPACE and BH-accelerated SPACE acquisition with 5% k-space sampling at 3 T. Spatial resolution and other parameters were matched when possible. BH SPACE images were reconstructed by enforcing joint multicoil sparsity in the wavelet domain (SPARSE-SPACE). Two board-certified radiologists independently evaluated BH SPARSE-SPACE and RT SPACE images for image quality parameters in the pancreatic duct and common bile duct by using a five-point scale. The Wilcoxon signed-rank test was used to compare BH SPARSE-SPACE and RT SPACE images. Results Acquisition time for BH SPARSE-SPACE was 20 seconds, which was significantly (P < .001) shorter than that for RT SPACE (mean ± standard deviation, 338.8 sec ± 69.1). Overall image quality scores were higher for BH SPARSE-SPACE than for RT SPACE images for both readers for the proximal, middle, and distal pancreatic duct, but the difference was not statistically significant (P > .05). For reader 1, distal common bile duct scores were significantly higher with BH SPARSE-SPACE acquisition (P = .036). More patients had acceptable or better overall image quality (scores ≥ 3) with BH SPARSE-SPACE than with RT SPACE acquisition, respectively, for the proximal (23 of 29 [79%] vs 22 of 29 [76%]), middle (22 of 29 [76%] vs 18 of 29 [62%]), and distal (20 of 29 [69%] vs 13 of 29 [45%]) pancreatic duct and the proximal (25 of 28 [89%] vs 22 of 28 [79%]) and distal (25 of 28 [89%] vs 24 of 28 [86%]) common bile duct. Conclusion BH SPARSE-SPACE showed similar or superior image quality for the pancreatic and common duct compared with that of RT SPACE despite 17-fold shorter acquisition time. (©) RSNA, 2016.
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Hersh
authors.initials: H
authors.lastname: Chandarana
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Ankur M
authors.initials: AM
authors.lastname: Doshi
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Alampady
authors.initials: A
authors.lastname: Shanbhogue
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: James S
authors.initials: JS
authors.lastname: Babb
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Mary T
authors.initials: MT
authors.lastname: Bruno
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Tiejun
authors.initials: T
authors.lastname: Zhao
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Esther
authors.initials: E
authors.lastname: Raithel
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Michael O
authors.initials: MO
authors.lastname: Zenge
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Guobin
authors.initials: G
authors.lastname: Li
authors.affiliation: From the Center for Advanced Imaging Innovation and Research (CAI2R) (H.C., J.S.B., R.O.) and Bernard and Irene Schwartz Center for Biomedical Imaging (H.C., A.M.D., A.S., J.S.B., M.T.B., R.O.), Department of Radiology, New York University School of Medicine, 660 First Ave, New York, NY 10016; Siemens Healthcare, New York, NY (T.Z., M.O.Z.); Siemens Healthcare, Erlangen, Germany (E.R.); and Department of Radiology, Section of Medical Physics, Freiburg University Medical Center, Freiburg, Germany (G.L.).
authors.forename: Ricardo
authors.initials: R
authors.lastname: Otazo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001652:Bile Ducts / Q000000981:diagnostic imaging; D062485:Breath Holding; D049448:Cholangiopancreatography, Magnetic Resonance / Q000379:methods*; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010182:Pancreatic Diseases / Q000000981:diagnostic imaging*; D010183:Pancreatic Ducts / Q000000981:diagnostic imaging; D011446:Prospective Studies