title: Microwave Ablation: The Differences Between Biliary Cirrhosis and Normal Porcine Liver Using a Cooled-tip Electrode.
abstract: OBJECTIVE
  To elucidate the difference in both in vivo and ex vivo microwave ablation in a biliary cirrhotic porcine liver model using a cooled-tip electrode.
  
  
  METHODS
  Microwave ablation with cooled-tip electrode was conducted under laparotomy. Morphological and pathological characteristics of the ablated areas were compared.
  
  
  RESULTS
  In the cirrhotic liver group, the in vivo ablated area was smaller than that ex vivo in terms of short and long axes, and volume. With the same ablation settings, both in vivo and ex vivo ablated areas in normal pig liver were larger than their counterparts in cirrhotic liver in terms of the short and long axes, and volume.
  
  
  CONCLUSIONS
  Both in vivo and ex vivo ablated areas in biliary cirrhotic pig liver were smaller than their counterparts in normal liver, suggesting that for the same amount of power, it requires a significantly longer duration to achieve the same ablated volume in cirrhotic liver compared to normal liver.
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Li-Gang
authors.initials: LG
authors.lastname: Wang
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Wen-Jin
authors.initials: WJ
authors.lastname: Jiang
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P.R. China fanweijun1964@126.com.
authors.forename: Wei-Jun
authors.initials: WJ
authors.lastname: Fan
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Yan-Bo
authors.initials: YB
authors.lastname: Zheng
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Xue-Peng
authors.initials: XP
authors.lastname: Song
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Liu
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Bo-Lin
authors.initials: BL
authors.lastname: Sun
authors.affiliation: Department of Medical Imaging & Interventional Radiology, Yu Huang Ding Hospital, Qing Dao University Medical College, Yantai, Shandong, P.R. China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
mesh_terms: D055011:Ablation Techniques / Q000295:instrumentation*; D000818:Animals; D004195:Disease Models, Animal; D004566:Electrodes; D004867:Equipment Design; D008099:Liver / Q000473:pathology / Q000601:surgery*; D008105:Liver Cirrhosis, Biliary / Q000473:pathology / Q000601:surgery*; D008872:Microwaves; D013552:Swine; D013556:Swine, Miniature; D007507:Therapeutic Irrigation / Q000295:instrumentation*; D013997:Time Factors
keywords: Microwave ablation; animal model; liver cirrhosis; pigs