title: Utility of an allograft tendon for scoliosis correction via the costo-transverse foreman.
abstract: Current convex tethering techniques for treatment of scoliosis have centered on anterior convex staples or polypropylene tethers. We hypothesized that an allograft tendon tether inserted via the costo-transverse foramen would correct an established spinal deformity. In the pilot study, six 8-week-old pigs underwent allograft tendon tethering via the costo-transverse foreman or sham to test the strength of the transplanted tendon to retard spine growth. After 4 months, spinal deformity in three planes was induced in all animals with allograft tendons. In the treatment study, the allograft tendon tether was used to treat established scoliosis in 11 8-week-old pigs (spinal deformity > 50°). Once the deformity was observed (4 months) animals were assigned to either no treatment group or allograft tendon tether group and progression assessed by monthly radiographs. At final follow-up, coronal Cobb angle and maximum vertebral axial rotation of the treatment group was significantly smaller than the non-treatment group, whereas sagittal kyphosis of the treatment group was significantly larger than the non-treatment group. In sum, a significant correction was achieved using a unilateral allograft tendon spinal tether, suggesting that an allograft tendon tethering approach may represent a novel fusion-less procedure to correct idiopathic scoliosis. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:183-192, 2017.
authors.affiliation: Orthopedic Department of Southwest Hospital, Third Military Medical University, 30 Gao Tan-Yan Road, Chongqing 400038, P.R. China.|Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: Dong
authors.initials: D
authors.lastname: Sun
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: Michael
authors.initials: M
authors.lastname: McCarthy
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: Adam C
authors.initials: AC
authors.lastname: Dooley
authors.affiliation: Department of Radiology, Arkansas Children's Hospital, 1 Children's Way, Slot 839, Little Rock 72202, Arkansas.
authors.forename: Raghu H
authors.initials: RH
authors.lastname: Ramakrishnaiah
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: R Shane
authors.initials: RS
authors.lastname: Shelton
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: Sandra G
authors.initials: SG
authors.lastname: McLaren
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Skinner
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.
authors.forename: Larry J
authors.initials: LJ
authors.lastname: Suva
authors.affiliation: Department of Orthopedic Surgery, Center for Orthopedic Research University of Arkansas for Medical Sciences, 4301 W. Markham, Slot 644, Little Rock 72205, Arkansas.|Department of Orthopedic Surgery, Arkansas Children's Hospital, 1 Children's Way, Slot 839, Little Rock 72202, Arkansas.
authors.forename: Richard E
authors.initials: RE
authors.lastname: McCarthy
mesh_terms: D064591:Allografts; D000818:Animals; D010865:Pilot Projects; D012600:Scoliosis / Q000601:surgery*; D013552:Swine; D013710:Tendons / Q000637:transplantation*
keywords: costo-transverse foramen; scoliosis correction; tethering