title: Multiple eruptive dermatofibromas.
abstract: We report a 34 year-old woman with psoriasis, systemic lupus erythematosus (SLE), and recent anti-TNFa therapy, who presented with multiple, eruptive dermatofibromas (MEDF). Although the pathogenesis of MEDF remains unknown, there is substantial evidence that this phenomenon represents an aberrant immune response. Like the more common presentation of solitary dermatofibromas, these lesions are benign, and no treatment is required. However, MEDF is increasingly recognized as a sign of immune dysregulation and an appropriate work-up should be initiated to identify an underlying cause in patients without a known trigger.
authors.affiliation: New York University School of Medicine.
authors.forename: Shields
authors.initials: S
authors.lastname: Callahan
authors.forename: Kathryn
authors.initials: K
authors.lastname: Matires
authors.forename: Marianna
authors.initials: M
authors.lastname: Shvartsbeyn
authors.forename: Nooshin
authors.initials: N
authors.lastname: Brinster
mesh_terms: D000328:Adult; D001706:Biopsy; D005260:Female; D018219:Histiocytoma, Benign Fibrous / Q000473:pathology*; D006801:Humans; D012867:Skin / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*