title: Gout: optimizing treatment to achieve a disease cure.
abstract: Gout is one of the most common inflammatory arthritides. The disease is due to the deposition of monosodium urate crystals. These deposits are reversible with proper treatment, suggesting that gout is a curable disease. The main aim in gout is to lower serum uric acid levels to a pre-established target; there are different urate-lowering drugs (xanthine oxidase inhibitors, uricosurics and uricases) through which this can be achieved. Proper treatment of gout also involves correct management of acute flares and their prevention. To ensure treatment adherence it is necessary to explain to the patient what the objectives are.
authors.affiliation: Sección de Reumatología, Hospital General Universitario de Alicante, Pintor Baeza 12, Alicante, 03010, Spain.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Bernal
authors.affiliation: Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain.
authors.forename: Neus
authors.initials: N
authors.lastname: Quilis
authors.affiliation: Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain.
authors.forename: Mariano
authors.initials: M
authors.lastname: Andrés
authors.affiliation: Sección de Reumatología, Hospital General Universitario de Elda, Alicante, Spain.
authors.forename: Francisca
authors.initials: F
authors.lastname: Sivera
authors.affiliation: Sección de Reumatología, Hospital General Universitario de Alicante, Alicante, Spain; Departamento de Medicina (Reumatología), Universidad Miguel Hernández, Alicante, Spain.
authors.forename: Eliseo
authors.initials: E
authors.lastname: Pascual
keywords: allopurinol; colchicine; gout; monosodium urate crystals; uric acid