title: Platelet-rich plasma as a novel treatment for lichen planopillaris.
abstract: Treatment of lichen planopillaris (LPP) remains a significant challenge due to the irreversible damage inflicted on hair follicles combined with the low efficacy of existing treatments. We hypothesized that growth factors released by the use of platelet-rich plasma (PRP) may arrest the development of LPP. To test our hypothesis, we treated an LPP patient that has failed previous treatments with a new PRP regimen. Following PRP treatment and six months follow-up, the patient experienced complete regression of itching and hair shedding. To the best of our knowledge, this is the first report of successful treatment of LPP with a PRP regimen.
authors.affiliation: Department of Dermatovenereology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
authors.forename: Željana
authors.initials: Ž
authors.lastname: Bolanča
authors.affiliation: University of Rome ("G. Marconi"), Rome, Italy.
authors.forename: Andy
authors.initials: A
authors.lastname: Goren
authors.affiliation: Clinical Unit for Laboratory Hematology and Coagulation, Clinical Institute of Chemistry, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
authors.forename: Biserka
authors.initials: B
authors.lastname: Getaldić-Švarc
authors.affiliation: Department of Pathology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
authors.forename: Majda
authors.initials: M
authors.lastname: Vučić
authors.affiliation: Department of Dermatovenereology, University Hospital Center Sestre milosrdnice, Zagreb, Croatia.
authors.forename: Mirna
authors.initials: M
authors.lastname: Šitum
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008010:Lichen Planus / Q000473:pathology / Q000628:therapy*; D053657:Platelet-Rich Plasma
keywords: alopecia; cicatricial alopecia; lichen planopillaris; local therapy; platelet-rich plasma