title: Colorimetric detection based on localised surface plasmon resonance of gold nanoparticles: Merits, inherent shortcomings and future prospects.
abstract: Localised surface plasmon resonance (LSPR) of gold nanoparticles (AuNPs) has been exploited for two decades in analytical science and has proven to be a powerful tool for the detection of various kinds of substances including small molecules, ions, macro biomolecules and microbes. Detection can be performed by visual colour change observations, photometry or resonance light scattering. A wide range of applications have been studied in the areas of environmental, pharmaceutical and biological analysis and clinical diagnosis. In this article, some fundamental aspects and important applications involving LSPR of AuNPs are reviewed. Several inherent shortcomings of these techniques and possible strategies to circumvent them are discussed.
authors.affiliation: School of Chemistry, The University of Melbourne, Victoria 3010, Australia.
authors.forename: Yanlin
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: School of Chemistry, The University of Melbourne, Victoria 3010, Australia; School of Geography, Earth and Environmental Sciences, Plymouth University, Plymouth PL4 8AA, United Kingdom. Electronic address: iandm@unimelb.edu.au.
authors.forename: Ian D
authors.initials: ID
authors.lastname: McKelvie
authors.affiliation: School of Chemistry, The University of Melbourne, Victoria 3010, Australia.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Cattrall
authors.affiliation: School of Chemistry, The University of Melbourne, Victoria 3010, Australia; Centre for Aquatic Pollution Identification and Management (CAPIM), The University of Melbourne, Victoria 3010, Australia. Electronic address: s.kolev@unimelb.edu.au.
authors.forename: Spas D
authors.initials: SD
authors.lastname: Kolev
keywords: Colorimetric detection; Gold nanoparticles; Localised surface plasmon resonance