title: Organization of lipids in fiber-cell plasma membranes of the eye lens.
abstract: The plasma membrane together with the cytoskeleton forms the only supramolecular structure of the matured fiber cell which accounts for mostly all fiber cell lipids. The purpose of this review is to inform researchers about the importance of the lipid bilayer portion of the lens fiber cell plasma membranes in the maintaining lens homeostasis, and thus protecting against cataract development.
authors.affiliation: Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA. Electronic address: subczyn@mcw.edu.
authors.forename: Witold K
authors.initials: WK
authors.lastname: Subczynski
authors.affiliation: Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: Laxman
authors.initials: L
authors.lastname: Mainali
authors.affiliation: Department of Biophysics, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Department of Medical Physics and Biophysics, School of Medicine, University of Split, Split, Croatia.
authors.forename: Marija
authors.initials: M
authors.lastname: Raguz
authors.affiliation: Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, WI 53226, USA.
authors.forename: William J
authors.initials: WJ
authors.lastname: O'Brien
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D007908:Lens, Crystalline / Q000378:metabolism*; D008051:Lipid Bilayers / Q000378:metabolism; D008560:Membrane Fluidity; D008563:Membrane Lipids / Q000378:metabolism; D010100:Oxygen / Q000378:metabolism; D010743:Phospholipids / Q000378:metabolism
chemical_list: D008051:Lipid Bilayers; D008563:Membrane Lipids; D010743:Phospholipids; D002784:Cholesterol; D010100:Oxygen
keywords: Cholesterol; Cholesterol bilayer domain; Cholesterol crystals; Membrane domains; Oxygen permeation; Spin labeling