title: Identification of bovine viral diarrhea virus infection in Saanen goats in the Republic of Korea.
abstract: Bovine viral diarrhea virus (BVDV) is one of the most important viral pathogens of livestock and causes substantial economic losses to the livestock industry worldwide. BVDV is not necessarily species specific and is known to infect domesticated and wild ruminants. In the present study, BVDV infection was identified in two Saanen goats from one farm, and two different viral subtypes were found, BVDV-1a and BVDV-2a. Each isolate was closely related to cattle isolates identified in the Republic of Korea. The two sequences obtained in this study were not consistent with border disease virus (BDV). The incidence of BVDV in this farm apparently occurred in the absence of contact with cattle and may be associated with grazing. This study demonstrates that BVDV infection may be possible to transmit among goats without exposure to cattle. Therefore, this result indicates that Saanen goats may act as natural reservoirs for BVDV. This is the first report of BVDV-1a infection in a Saanen goat.
authors.affiliation: College of Ecology and Environmental Science, Kyungpook National University, Sangju, 37224, Republic of Korea.
authors.forename: Yu-Jung
authors.initials: YJ
authors.lastname: Han
authors.affiliation: Laboratory of Veterinary Internal Medicine, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
authors.forename: Jeong-Byoung
authors.initials: JB
authors.lastname: Chae
authors.affiliation: Laboratory of Veterinary Internal Medicine, BK21 PLUS Program for Creative Veterinary Science Research, Research Institute for Veterinary Science and College of Veterinary Medicine, Seoul National University, Seoul, 08826, Republic of Korea.
authors.forename: Joon-Seok
authors.initials: JS
authors.lastname: Chae
authors.affiliation: College of Veterinary Medicine, Chonnam National University, Gwangju, 61186, Republic of Korea.
authors.forename: Do-Hyeon
authors.initials: DH
authors.lastname: Yu
authors.affiliation: College of Veterinary Medicine, Chonbuk National University, Iksan, 54596, Republic of Korea.
authors.forename: Jinho
authors.initials: J
authors.lastname: Park
authors.affiliation: College of Veterinary Medicine, Chungnam National University, Daejeon, 34134, Republic of Korea.
authors.forename: Bae-Keun
authors.initials: BK
authors.lastname: Park
authors.affiliation: College of Veterinary Medicine, Kangwon National University, Chuncheon, 24341, Republic of Korea.
authors.forename: Hyeon-Cheol
authors.initials: HC
authors.lastname: Kim
authors.affiliation: Laboratory of Veterinary Clinics, National Institute of Animal Science Rural Development Administration, Jeonju, 54875, Republic of Korea.
authors.forename: Jae-Gyu
authors.initials: JG
authors.lastname: Yoo
authors.affiliation: College of Ecology and Environmental Science, Kyungpook National University, Sangju, 37224, Republic of Korea. kschoi3@knu.ac.kr.
authors.forename: Kyoung-Seong
authors.initials: KS
authors.lastname: Choi
mesh_terms: D000818:Animals; D030241:Diarrhea Virus 1, Bovine Viral / Q000235:genetics / Q000302:isolation & purification*; D030242:Diarrhea Virus 2, Bovine Viral / Q000235:genetics / Q000302:isolation & purification*; D004197:Disease Reservoirs / Q000662:veterinary / Q000821:virology; D005814:Genes, Viral; D015511:Goat Diseases / Q000453:epidemiology* / Q000821:virology; D006041:Goats; D018182:Pestivirus Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D056910:Republic of Korea / Q000453:epidemiology; D017422:Sequence Analysis, DNA / Q000662:veterinary
keywords: BVDV-1a; BVDV-2a; Bovine viral diarrhea virus; Reservoir; Saanen goat