title: Pathologic activation of thrombopoietin receptor and JAK2-STAT5 pathway by frameshift mutants of mouse calreticulin.
authors.affiliation: Ludwig Institute for Cancer Research Brussels, Brussels, Belgium.|SIGN Pole, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: T
authors.initials: T
authors.lastname: Balligand
authors.affiliation: LPAD Pole, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: Y
authors.initials: Y
authors.lastname: Achouri
authors.affiliation: Ludwig Institute for Cancer Research Brussels, Brussels, Belgium.|SIGN Pole, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: C
authors.initials: C
authors.lastname: Pecquet
authors.affiliation: Ludwig Institute for Cancer Research Brussels, Brussels, Belgium.|SIGN Pole, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: I
authors.initials: I
authors.lastname: Chachoua
authors.affiliation: Genetics of Hematological Disorders, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
authors.forename: H
authors.initials: H
authors.lastname: Nivarthi
authors.affiliation: INSERM, UMR1170, Villejuif, France.|Paris-Saclay, UMR1170, Villejuif, France.|Gustave Roussy, UMR1170, Villejuif, France.
authors.forename: C
authors.initials: C
authors.lastname: Marty
authors.affiliation: INSERM, UMR1170, Villejuif, France.|Paris-Saclay, UMR1170, Villejuif, France.|Gustave Roussy, UMR1170, Villejuif, France.
authors.forename: W
authors.initials: W
authors.lastname: Vainchenker
authors.affiliation: INSERM, UMR1170, Villejuif, France.|Paris-Saclay, UMR1170, Villejuif, France.|Gustave Roussy, UMR1170, Villejuif, France.
authors.forename: I
authors.initials: I
authors.lastname: Plo
authors.affiliation: Genetics of Hematological Disorders, CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
authors.forename: R
authors.initials: R
authors.lastname: Kralovics
authors.affiliation: Ludwig Institute for Cancer Research Brussels, Brussels, Belgium.|SIGN Pole, de Duve Institute, Université catholique de Louvain, Brussels, Belgium.
authors.forename: S N
authors.initials: SN
authors.lastname: Constantinescu
mesh_terms: D000818:Animals; D037282:Calreticulin / Q000235:genetics*; D002471:Cell Transformation, Neoplastic / Q000235:genetics; D016368:Frameshift Mutation; D006801:Humans; D053614:Janus Kinase 2 / Q000378:metabolism*; D051379:Mice; D053628:Receptors, Thrombopoietin / Q000378:metabolism*; D050799:STAT5 Transcription Factor / Q000378:metabolism*; D015398:Signal Transduction / Q000502:physiology
chemical_list: D037282:Calreticulin; C481270:Mpl protein, mouse; D053628:Receptors, Thrombopoietin; D050799:STAT5 Transcription Factor; C507926:Jak2 protein, mouse; D053614:Janus Kinase 2