title: Enhanced fluorescent resonant energy transfer of DNA conjugates complexed with surfactants and divalent metal ions.
abstract: Dimerization and resultant quenching of donor and acceptor dyes conjugated on DNA causes loss of fluorescent resonant energy transfer (FRET) efficiency. However, when complexed with surfactants and divalent metal ions, sheathing effects insulate and shield the DNA structures, reducing dimerization and quenching which leads to significant enhancement of FRET efficiency.
authors.affiliation: Materials Science and Engineering, University of California, San Diego, 9500 Gilman Dr., La Jolla, CA 92093, USA.
authors.forename: Taeseok
authors.initials: T
authors.lastname: Oh
authors.forename: Jae-Young
authors.initials: JY
authors.lastname: Choi
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Heller
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry* / Q000235:genetics; D031541:Fluorescence Resonance Energy Transfer / Q000379:methods*; D008670:Metals / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry*; D014966:Xanthenes / Q000737:chemistry
chemical_list: D008670:Metals; D013501:Surface-Active Agents; D014966:Xanthenes; C034657:Texas red; D004247:DNA