title: Foetal fibular hemimelia with focal femoral deficiency following prenatal misoprostol use: A case report.
abstract: Misoprostol is a well known abortifacient. It can cause teratogenicity like Mobius sequence and terminal transverse limb defects. We report a rare case of proximal focal femoral deficiency with fibular hemimelia in a woman who had attempted abortion with self-administered misoprostol and later continued the pregnancy. Though the absolute risk of congenital malformations with its use is low ∼1%, this should be clearly communicated to the women requesting abortion to help them make fully informed reproductive health decisions.
authors.affiliation: a Department of Obstetrics and Gynaecology , Mahatma Gandhi Medical College and Research Institute , Pillaiyarkuppam , Pondy, Cuddalore Main Road , Puducherry , India.
authors.forename: P
authors.initials: P
authors.lastname: Pallavee
authors.affiliation: a Department of Obstetrics and Gynaecology , Mahatma Gandhi Medical College and Research Institute , Pillaiyarkuppam , Pondy, Cuddalore Main Road , Puducherry , India.
authors.forename: Rupal
authors.initials: R
authors.lastname: Samal
authors.affiliation: a Department of Obstetrics and Gynaecology , Mahatma Gandhi Medical College and Research Institute , Pillaiyarkuppam , Pondy, Cuddalore Main Road , Puducherry , India.
authors.forename: Jasmina
authors.initials: J
authors.lastname: Begum
authors.affiliation: a Department of Obstetrics and Gynaecology , Mahatma Gandhi Medical College and Research Institute , Pillaiyarkuppam , Pondy, Cuddalore Main Road , Puducherry , India.
authors.forename: Seetesh
authors.initials: S
authors.lastname: Ghose
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000196:embryology* / Q000209:etiology; D000020:Abortifacient Agents, Nonsteroidal / Q000009:adverse effects*; D000028:Abortion, Induced / Q000009:adverse effects*; D000328:Adult; D004480:Ectromelia / Q000139:chemically induced* / Q000196:embryology; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005333:Fetus / Q000002:abnormalities / Q000187:drug effects / Q000196:embryology; D005360:Fibula / Q000002:abnormalities / Q000196:embryology; D006801:Humans; D008297:Male; D016595:Misoprostol / Q000009:adverse effects*; D011247:Pregnancy
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D016595:Misoprostol
keywords: Foetal; abortion; hemimelia; misoprostol