title: MULTIFOCAL CHOROIDITIS IN DISSEMINATED SPOROTRICHOSIS IN PATIENTS WITH HIV/AIDS.
abstract: OBJECTIVE
  In this article, the authors describe multifocal choroiditis related to disseminated sporotrichosis in patients with HIV/AIDS.
  
  
  METHODS
  We conducted a retrospective observational study of three patients infected with HIV who presented with disseminated sporotrichosis characterized by cutaneous lesions, multifocal choroiditis, and other manifestations, including osteomyelitis and involvement of the bone marrow, larynx, pharynx, and nasal and oral mucosa.
  
  
  RESULTS
  Five eyes of three patients with HIV/AIDS showed multifocal choroiditis related to disseminated sporotrichosis. The CD4 counts ranged from 25 to 53 mm. All patients were asymptomatic visually. The ocular disease was bilateral in two patients. The lesion size ranged from 1/3 to 2 disc diameters. None of the patients had vitritis. Of the 12 lesions, 9 were localized in the posterior pole (Zone 1) and 3 were localized in the mild periphery (Zone 2).
  
  
  CONCLUSIONS
  Multifocal choroiditis due to disseminated sporotrichosis can occur in profoundly immunosuppressed patients with HIV/AIDS.
authors.affiliation: *Laboratório de Pesquisa Clínica em Oftalmologia Infecciosa, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil; †Laboratório de Pesquisa Clínica em Dermatologia Infecciosa, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil; ‡Centro Hospitalar do Instituto Nacional de Infectologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil; and §Laboratório de Micologia, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
authors.forename: Ana L
authors.initials: AL
authors.lastname: Biancardi
authors.forename: Dayvison F S
authors.initials: DF
authors.lastname: Freitas
authors.forename: Vitor R G de A
authors.initials: VR
authors.lastname: Valviesse
authors.forename: Hugo B
authors.initials: HB
authors.lastname: Andrade
authors.forename: Manoel M E
authors.initials: MM
authors.lastname: de Oliveira
authors.forename: Antonio C F
authors.initials: AC
authors.lastname: do Valle
authors.forename: Rosely M
authors.initials: RM
authors.lastname: Zancope-Oliveira
authors.forename: Maria C G
authors.initials: MC
authors.lastname: Galhardo
authors.forename: Andre L L
authors.initials: AL
authors.lastname: Curi
mesh_terms: D000328:Adult; D002833:Choroiditis / Q000382:microbiology*; D015821:Eye Infections, Fungal / Q000382:microbiology*; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008297:Male; D000080364:Multifocal Choroiditis; D012189:Retrospective Studies; D013175:Sporothrix / Q000302:isolation & purification; D013174:Sporotrichosis / Q000209:etiology*