title: Surgical management of inflammatory bowel disease: A low prevalence, developing country perspective.
abstract: OBJECTIVE
  To determine the outcomes of surgical management of inflammatory bowel disease.
  
  
  METHODS
  The retrospective case series was conducted at Aga Khan University Hospital, Karachi, and comprised medical record of adult patients operated between January 1986 and December 2010 for inflammatory bowel disease. Outcomes consisted of complications till last follow-up and 30-day mortality (disease or procedure related). Functional status of patients with ileal pouch was determined via telephone. SPSS 16 was used to analyse data.
  
  
  RESULTS
  Of the 36 patients whose records were reviewed, 21(58%) were males, and body mass index was less than 23 in 34(91%). A total of 27(75%) patients underwent elective surgery for their condition. Ileal pouch was formed in 9(25%). Overall mortality was 14(38.8%). Overall incidence of complications was 26(72%), with wound infection being the most common early morbidity in 11(30.5%). Late morbidity included pouchitisin 4/9 (44.9%) and strictures 2/36 (5.5%).On telephonic follow-up, 6 of the remaining 7patients (85%) with ileal pouch were satisfied with the functional results of the procedure.
  
  
  CONCLUSIONS
  The retrospective case series represents results from a developing country with low prevalence of inflammatory bowel disease and hence limited experience.
authors.affiliation: Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Sana
authors.initials: S
authors.lastname: Nasim
authors.affiliation: Department of Surgery, The Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Tabish
authors.initials: T
authors.lastname: Chawla
authors.affiliation: Department of Surgery, General Surgery, Memon Medical Institute Hospital, Safoora Goth, Karachi, Pakistan.
authors.forename: Ghulam
authors.initials: G
authors.lastname: Murtaza
mesh_terms: D000328:Adult; D003082:Colectomy; D039021:Colonic Pouches; D003906:Developing Countries; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000453:epidemiology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010154:Pakistan / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology; D019449:Pouchitis / Q000453:epidemiology; D015995:Prevalence; D016737:Proctocolectomy, Restorative; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000453:epidemiology
keywords: Inflammatory bowel disease, Morbidity, Mortality, Ileal pouch, Anal anastamosis.