title: Suppression of melanin synthesis by Americanin A in melan-a cells via regulation of microphthalmia-associated transcription factor.
authors.affiliation: College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Yoonho
authors.initials: Y
authors.lastname: Shin
authors.affiliation: College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Eun Jung
authors.initials: EJ
authors.lastname: Jang
authors.affiliation: College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Hyen Joo
authors.initials: HJ
authors.lastname: Park
authors.affiliation: College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Ji-Young
authors.initials: JY
authors.lastname: Hong
authors.affiliation: College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Sam Sik
authors.initials: SS
authors.lastname: Kang
authors.affiliation: College of Pharmacy, Natural Products Research Institute, Seoul National University, Seoul, 151-742, Korea.
authors.forename: Sang Kook
authors.initials: SK
authors.lastname: Lee
mesh_terms: D000818:Animals; D002460:Cell Line; D004147:Dioxins / Q000494:pharmacology*; D004353:Drug Evaluation, Preclinical; D008543:Melanins / Q000096:biosynthesis*; D008544:Melanocytes / Q000187:drug effects* / Q000378:metabolism; D051379:Mice; D051739:Microphthalmia-Associated Transcription Factor / Q000378:metabolism*; D014442:Monophenol Monooxygenase / Q000378:metabolism; D062327:Skin Lightening Preparations / Q000494:pharmacology*
chemical_list: D004147:Dioxins; D008543:Melanins; D051739:Microphthalmia-Associated Transcription Factor; C497235:Mitf protein, mouse; D062327:Skin Lightening Preparations; C055021:americanin A; D014442:Monophenol Monooxygenase
keywords: c-kit; melanogenesis; microphthalmia-associated transcription factor (MITF); natural lignan; tyrosinase