title: Quantification of adipose volume reduction with a prospective study analyzing the application of external radiofrequency energy and high voltage ultrashort pulse duration electrical fields.
abstract: To date, there have been no objective measurements of subcutaneous volume loss following treatments with a noninvasive radiofrequency (RF)-based device. Twenty female patients were treated with a suction-coupled bipolar RF device using external RF energy combined with pulsed electromagnetic RF energy for subcutaneous fat reduction. Parameters followed included weight, Vectra measurements of abdominal circumference and torso volume, and high-definition ultrasound measurements of fat thickness. Measurements were taken before treatment and three times following treatment. Analysis of the measured parameters showed that mean circumference reduction of 2.30 cm was noted at three months post-treatment. Independent volumetric analysis showed a mean subcutaneous volume reduction of 428 cc three months following RF treatment. High-resolution ultrasound fat thickness was reduced by a mean of 39.6% three months following the final BodyFX treatment. Independent and paired-sample t-tests showed a p value of < 0.05. Repeated measures of analysis of covariance (ANCOVA) adjusted for differences in age, as well as height and weight (proxy for body mass index) to minimize individual differences and control for extraneous variables that may affect the pre- and post-treatment results were analyzed. No confounding variables were found. All analyses were conducted using IBM SPSS 21.0.
authors.affiliation: a Plastic Surgical Associates of Fort Collins, Plastic Surgery , Fort Collins , CO , USA.
authors.forename: Diane Irvine
authors.initials: DI
authors.lastname: Duncan
authors.affiliation: b York University , Toronto, Ontario , Canada.
authors.forename: Theresa H M
authors.initials: TH
authors.lastname: Kim
authors.affiliation: a Plastic Surgical Associates of Fort Collins, Plastic Surgery , Fort Collins , CO , USA.
authors.forename: Robbin
authors.initials: R
authors.lastname: Temaat
mesh_terms: D000328:Adult; D003238:Connective Tissue / Q000528:radiation effects; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D056128:Obesity, Abdominal / Q000532:radiotherapy* / Q000628:therapy; D000078702:Radiofrequency Therapy; D050151:Subcutaneous Fat / Q000528:radiation effects*; D050507:Subcutaneous Fat, Abdominal / Q000528:radiation effects*
keywords: Adipocyte; adipocytolysis; apoptosis; body contouring; fat reduction; noninvasive; radiofrequency