title: [The relaxation time anisotropy as a method of assessment of physico-chemical activity of the cerebrospinal fluid in acute stroke].
abstract: OBJECTIVE
  To study the anisotropy relaxation time of the cerebrospinal fluid (CSF) in acute disorders of cerebral circulation compared by analyzing the kinetics of anisotropy relaxation of the dye «rhodamine 6G».
  
  
  METHODS
  The study of the samples was performed using a laser confocal fluorescence microscope MicroTime 200 («PicoQuant GmbH»). Authors used a laser operating at a wavelength of 470 nm with a time resolution of 8 PS with a pulse frequency of 10 MHz.
  
  
  RESULTS
  Authors assessed this parameter in CSF of patients with different types of stroke.
  
  
  CONCLUSIONS
  Confocal laser spectrometry can be considered as an objective method of studying CSF changes in patients with lesions of the central nervous system and control of patient status in a clinical setting.
authors.affiliation: Irkutsk State Medical Academy of Postgraduate Education, Irkutsk.
authors.forename: S V
authors.initials: SV
authors.lastname: Gorbachev
authors.affiliation: Irkutsk State Medical Academy of Postgraduate Education, Irkutsk.
authors.forename: V I
authors.initials: VI
authors.lastname: Gorbachev
authors.affiliation: Institute of Laser Physics of Siberian Branch of Russian Academy of Sciences, Irkutsk.
authors.forename: A V
authors.initials: AV
authors.lastname: Bartul'
authors.affiliation: Institute of Laser Physics of Siberian Branch of Russian Academy of Sciences, Irkutsk.
authors.forename: S A
authors.initials: SA
authors.lastname: Zilov
authors.affiliation: Irkutsk State Medical Academy of Postgraduate Education, Irkutsk.
authors.forename: A V
authors.initials: AV
authors.lastname: Lohov