title: Understanding How DNA Enzymes Work.
abstract: Tied up in knots: The crystal structure of a DNA enzyme in its post-catalytic state was solved. The results provide insight into the structural possibilities for DNA and the mechanism of DNA catalysis.
authors.affiliation: Institut für Organische Chemie und Chemische Biologie, Biomolekulares Magnetresonanz-Zentrum (BMRZ), Goethe-Universität Frankfurt, Max-von-Laue-Strasse 7, 60438, Frankfurt am Main, Germany.
authors.forename: Julia
authors.initials: J
authors.lastname: Wirmer-Bartoschek
authors.affiliation: Institut für Organische Chemie und Chemische Biologie, Biomolekulares Magnetresonanz-Zentrum (BMRZ), Goethe-Universität Frankfurt, Max-von-Laue-Strasse 7, 60438, Frankfurt am Main, Germany. schwalbe@nmr.uni-frankfurt.de.
authors.forename: Harald
authors.initials: H
authors.lastname: Schwalbe
mesh_terms: D020134:Catalytic Domain; D018360:Crystallography, X-Ray; D021881:DNA, Catalytic / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D009690:Nucleic Acid Conformation; D012313:RNA / Q000378:metabolism
chemical_list: D021881:DNA, Catalytic; D012313:RNA
keywords: 9DB1; DNA structures; DNAzymes; X-ray diffraction