title: Outbreak of respiratory syncytial virus (RSV) infection in immunocompromised adults on a hematology ward.
abstract: We describe an outbreak of respiratory syncytial virus (RSV) infection on a hematology ward without allogeneic stem cell transplant patients. Twelve patients and one staff member infected with RSV were identified from the laboratory database. Five patients had lower respiratory tract infection, seven had upper respiratory tract infection, one was asymptomatic, and there were two (15.4%) deaths. Most patients had overlapping periods of potential infectiousness on the ward. Sequencing was possible on eight specimens and five of these had identical sequences. Results were consistent with transmission occurring both on the ward and by introduction of RSV from the community. J. Med. Virol. 88:1827-1831, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Infectious Diseases, St. Vincent's Hospital, Sydney, Australia.|School of Medical Sciences, University of New South Wales, Australia.
authors.forename: Tomas Ostergaard
authors.initials: TO
authors.lastname: Jensen
authors.affiliation: School of Medical Sciences, University of New South Wales, Australia.|Division of Serology and Virology, South Eastern Area Laboratory Services, Prince of Wales Hospital, Sydney, Australia.
authors.forename: Sacha
authors.initials: S
authors.lastname: Stelzer-Braid
authors.affiliation: Division of Serology and Virology, South Eastern Area Laboratory Services, Prince of Wales Hospital, Sydney, Australia.
authors.forename: Christiana
authors.initials: C
authors.lastname: Willenborg
authors.affiliation: Department of Haematology, Prince of Wales Hospital, Sydney, Australia.
authors.forename: Carol
authors.initials: C
authors.lastname: Cheung
authors.affiliation: Department of Infectious Diseases, St. Vincent's Hospital, Sydney, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Andresen
authors.affiliation: School of Medical Sciences, University of New South Wales, Australia.|Division of Serology and Virology, South Eastern Area Laboratory Services, Prince of Wales Hospital, Sydney, Australia.|School of Biotechnology and Biomolecular Sciences, University of New South Wales, Australia.
authors.forename: William
authors.initials: W
authors.lastname: Rawlinson
authors.affiliation: Department of Infectious Diseases, Prince of Wales Hospital, Sydney, Australia.
authors.forename: Kate
authors.initials: K
authors.lastname: Clezy
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D058345:Asymptomatic Infections; D001315:Australia / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology* / Q000821:virology; D004196:Disease Outbreaks; D005260:Female; D006405:Hematology; D006757:Hospital Units; D006801:Humans; D016867:Immunocompromised Host; D008297:Male; D008875:Middle Aged; D018357:Respiratory Syncytial Virus Infections / Q000453:epidemiology* / Q000276:immunology* / Q000401:mortality / Q000821:virology; D018113:Respiratory Syncytial Virus, Human / Q000276:immunology / Q000302:isolation & purification
keywords: adults; epidemiology; hematology; immunosuppression; respiratory syncytial virus