title: Development of a biomechanical model of the wrist joint for patient-specific model guided surgical therapy planning: Part 1.
abstract: An enhanced musculoskeletal biomechanical model of the wrist joint is presented in this article. The developed computational model features the two forearm bones radius and ulna, the eight wrist bones, the five metacarpal bones, and a soft tissue apparatus. Validation of the model was based on information taken from the literature as well as own experimental passive in vitro motion analysis of eight cadaver specimens. The computational model is based on the multi-body simulation software AnyBody. A comprehensive ligamentous apparatus was implemented allowing the investigation of ligament function. The model can easily patient specific personalized on the basis of image information. The model enables simulation of individual wrist motion and predicts trends correctly in the case of changing kinematics. Therefore, patient-specific multi-body simulation models are potentially valuable tools for surgeons in pre- and intraoperative planning of implant placement and orientation.
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany Department of Orthopaedic, University Hospital Aachen, RWTH Aachen University, Aachen, Germany eschweiler@hia.rwth-aachen.de.
authors.forename: Jörg
authors.initials: J
authors.lastname: Eschweiler
authors.affiliation: Department of Plastic Surgery, Hand and Burns Surgery, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: Jan-Philipp
authors.initials: JP
authors.lastname: Stromps
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany.
authors.forename: Maximilian
authors.initials: M
authors.lastname: Fischer
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany.
authors.forename: Fabian
authors.initials: F
authors.lastname: Schick
authors.affiliation: Department of Orthopaedic, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: Björn
authors.initials: B
authors.lastname: Rath
authors.affiliation: Department of Plastic Surgery, Hand and Burns Surgery, University Hospital Aachen, RWTH Aachen University, Aachen, Germany.
authors.forename: Norbert
authors.initials: N
authors.lastname: Pallua
authors.affiliation: Helmholtz-Institute for Biomedical Engineering, Chair of Medical Engineering, RWTH Aachen University, Aachen, Germany.
authors.forename: Klaus
authors.initials: K
authors.lastname: Radermacher
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000465:Algorithms; D001696:Biomechanical Phenomena; D002348:Carpal Bones / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D011884:Radius / Q000000981:diagnostic imaging; D016059:Range of Motion, Articular / Q000502:physiology; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014955:Wrist Joint / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology / Q000601:surgery
keywords: Wrist joint; biomechanics; computational model; multi-body simulation; therapy planning