title: Is there a justification for hysterectomy in patients with borderline ovarian tumors?
abstract: OBJECTIVE
  To determine the frequency of uterine involvement in patients with borderline ovarian tumors (BOT) and to evaluate the recurrence risk and survival after hysterectomy.
  
  
  METHODS
  In two French hospitals: A tertiary referral centre (University hospital centre of Tours, France) and the Alliance community hospital of Tours (France), we reviewed data of consecutive women undergoing surgery for presumed stage I BOT between January 1997 and December 2012. Patients were divided into two groups: patients treated with fertility sparing surgery (group 1) and those treated with radical surgery (group 2).
  
  
  RESULTS
  A total of 135 patients were evaluated. 35 had fertility sparing surgery, 81 had radical surgery with hysterectomy and 19 had previous hysterectomy for other reasons. There were more recurrent borderline ovarian disease and more ovarian invasive disease developed in group 1 (p = 0.02, p = 0.04, respectively). Hysterectomy affected favorably borderline disease-free survival, OR = 0.09 95%CI (0.005-0.69), p = 0.04, but perceived benefits may be related to bilateral salpingo-oophorectomy and not hysterectomy directly.
authors.affiliation: Department of Gynecology, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044, Tours, France; INSERM Unit 1069, Tours, France; François-Rabelais University, Tours, France. Electronic address: l.ouldamer@chu-tours.fr.
authors.forename: L
authors.initials: L
authors.lastname: Ouldamer
authors.affiliation: Department of Gynecology, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044, Tours, France; François-Rabelais University, Tours, France.
authors.forename: C
authors.initials: C
authors.lastname: Lacoste
authors.affiliation: Department of Pathology, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044, Tours, France.
authors.forename: B
authors.initials: B
authors.lastname: Cormier
authors.affiliation: Department of Pathology, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044, Tours, France.
authors.forename: F
authors.initials: F
authors.lastname: Arbion
authors.affiliation: Department of Gynecology, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044, Tours, France; François-Rabelais University, Tours, France.
authors.forename: H
authors.initials: H
authors.lastname: Marret
authors.affiliation: Department of Pathology, Clinique de l'Alliance, 1 boulevard Alfred Nobel, 37540, St-Cyr-sur-Loire, France.
authors.forename: L
authors.initials: L
authors.lastname: Jallais
authors.affiliation: Department of Gynecology, Clinique de l'Alliance, 1 boulevard Alfred Nobel, 37540, St-Cyr-sur-Loire, France.
authors.forename: A
authors.initials: A
authors.lastname: Fignon
authors.affiliation: Department of Gynecology, Centre Hospitalier Régional Universitaire de Tours, Hôpital Bretonneau, 2 boulevard Tonnellé, 37044, Tours, France; François-Rabelais University, Tours, France.
authors.forename: G
authors.initials: G
authors.lastname: Body
mesh_terms: D005260:Female; D059247:Fertility Preservation; D006801:Humans; D007044:Hysterectomy / Q000379:methods*; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000473:pathology / Q000601:surgery*; D011379:Prognosis
keywords: Age; Borderline ovarian tumors; Fertility; Hysterectomy