title: [Impact of sex and age on the clinical and epidemiological aspects of childhood psoriasis: Data from a French cross-sectional multicentre study].
abstract: BACKGROUND
  The prevalence of childhood psoriasis is estimated at between 0.4% and 0.7%. Clinical aspects of the diseases depend on age. The aim of this study was to investigate the clinical aspects of psoriasis according to age and sex.
  
  
  METHODS
  A cross-sectional, multicentre study of children with psoriasis was performed by investigators belonging to the Research Group of the French Society of Paediatric Dermatology. The study was conducted from April 2012 to March 2013. Inclusion criteria were age less than 18 years and clinical diagnosis of psoriasis. The children were classified into 3 groups by age: infants: <2 years; children: ≥2 years and <13 years; adolescents≥13 years. The information collected included demographic data, clinical, epidemiological, and therapeutic aspects of the psoriasis, as well as analysis of comorbidities.
  
  
  RESULTS
  Three hundred and thirteen children were included: 27 (8.6%) infants, 207 (66.1%) children, and 79 (25.2%) adolescents. Plaque psoriasis was the most frequent clinical type of psoriasis seen in children and adolescents (>41%), but it accounted for only 25.9% of psoriasis of infants (P<0.0001). Napkin psoriasis (37.0%) and inverse psoriasis (22.2%) were the most common forms of psoriasis seen in infants and were described significantly more frequently in this group than in the two other groups (P<0.003). Nail involvement was more common in adolescents (37.2%, P=0.03) and children (32.9%) than in infants (14.8%) and affected boys more than girls (43.6% vs 22.0%, P<0.0001). Girls presented scalp psoriasis more frequently (17.7% vs 8.7%, P=0.02). Local vitamin-D treatment and systemic therapies were used more frequently in children and adolescents than in infants. There was no significant difference for treatment use, including for acitretin, according to gender.
  
  
  CONCLUSIONS
  Plaque psoriasis was the most common clinical type of psoriasis in children but affected less than 50% of the children. Age had a significant impact on extra-cutaneous skin disorders and on treatment used, while sex had little incidence. The frequency of comorbidities was not affected by age.
  
  
  CONCLUSIONS
  Childhood psoriasis thus presents specific characteristics dependent on the age of the child. The results of studies exclusively dealing with adults cannot be extrapolated to children.
authors.affiliation: Service de dermatologie, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil, France.
authors.forename: J
authors.initials: J
authors.lastname: Bonigen
authors.affiliation: Service de néphro-rhumato-dermatologie pédiatrique, hôpital Femme-Mère-Enfant, 69500 Bron, France.
authors.forename: A
authors.initials: A
authors.lastname: Phan
authors.affiliation: Service de dermatologie, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, université Paris-Descartes Sorbonne Paris Cité, 75015 Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Hadj-Rabia
authors.affiliation: Unité de dermatologie pédiatrique, hôpital Pellegrin-Enfants, 33000 Bordeaux, France.
authors.forename: F
authors.initials: F
authors.lastname: Boralévi
authors.affiliation: Service de dermatologie, hôpital Brabois, 54500 Vandœuvre-Lès-Nancy, France.
authors.forename: A-C
authors.initials: AC
authors.lastname: Bursztejn
authors.affiliation: Service de dermatologie, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, université Paris-Descartes Sorbonne Paris Cité, 75015 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Bodemer
authors.affiliation: Service de dermatologie, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, université Paris-Descartes Sorbonne Paris Cité, 75015 Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Ferneiny
authors.affiliation: Service de néphro-rhumato-dermatologie pédiatrique, hôpital Femme-Mère-Enfant, 69500 Bron, France.
authors.forename: A-L
authors.initials: AL
authors.lastname: Souillet
authors.affiliation: Service de dermatologie, hôpital Archet 2, ESPIC, CHU Lenval, 06000 Nice, France.
authors.forename: C
authors.initials: C
authors.lastname: Chiavérini
authors.affiliation: Service de pédiatrie générale, hôpital Robert-Debré, Assistance publique-Hôpitaux de Paris, 75019 Paris, France.
authors.forename: E
authors.initials: E
authors.lastname: Bourrat
authors.affiliation: Service de dermatologie, centre hospitalier universitaire Pontchaillou, 35000 Rennes, France; Service de pédiatrie, centre hospitalier universitaire Sud, 97410 Saint-Pierre, Réunion.
authors.forename: J
authors.initials: J
authors.lastname: Miquel
authors.affiliation: Service de dermatologie, hôpital du Bocage, centre hospitalier universitaire de Dijon, 21000 Dijon, France.
authors.forename: P
authors.initials: P
authors.lastname: Vabres
authors.affiliation: Service de dermatologie, Hôtel-Dieu, 44000 Nantes, France.
authors.forename: S
authors.initials: S
authors.lastname: Barbarot
authors.affiliation: Service de dermatologie, centre hospitalier Saint-Éloi, 34000 Montpellier, France.
authors.forename: D
authors.initials: D
authors.lastname: Bessis
authors.affiliation: Service de dermatologie, hôpital Robert-Debré, 51100 Reims, France.
authors.forename: C
authors.initials: C
authors.lastname: Eschard
authors.affiliation: Service de dermatologie, hôpital Larrey, université P.-Sabatier, 31059 Toulouse cedex 09, France.
authors.forename: J
authors.initials: J
authors.lastname: Mazereeuw-Hautier
authors.affiliation: Service de rhumatologie pédiatrique, CeRéMAI, université Paris Sud, centre hospitalier universitaire de Bicêtre, 94270 Le Kremlin-Bicêtre, France.
authors.forename: M
authors.initials: M
authors.lastname: Piram
authors.affiliation: Service de dermatologie, centre hospitalier de Cornouaille, 29000 Quimper, France.
authors.forename: P
authors.initials: P
authors.lastname: Plantin
authors.affiliation: Service de dermatologie, hôpital Morvan, 22000 Brest, France.
authors.forename: C
authors.initials: C
authors.lastname: Abasq
authors.affiliation: Service de dermatologie, hôpital Saint-Vincent de Paul, université catholique de Lille, 59000 Lille, France.
authors.forename: A
authors.initials: A
authors.lastname: Lasek-Duriez
authors.affiliation: Service de dermatologie, hôpital Trousseau, université François-Rabelais, CHRU de Tours, 37044 Tours cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Maruani
authors.affiliation: Département de santé publique, centre hospitalier universitaire Ambroise-Paré, université Versailles-Saint-Quentin-en-Yvelines, Assistance publique-Hôpitaux de Paris, 92100 Boulogne-Billancourt, France.
authors.forename: A
authors.initials: A
authors.lastname: Beauchet
authors.affiliation: Service de dermatologie, hôpital Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prud'hon, 95107 Argenteuil, France. Electronic address: emmanuel.mahe@ch-argenteuil.fr.
authors.forename: E
authors.initials: E
authors.lastname: Mahé
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003430:Cross-Sectional Studies; D005260:Female; D005602:France / Q000453:epidemiology; D006801:Humans; D007223:Infant; D008297:Male; D009260:Nail Diseases / Q000453:epidemiology; D011565:Psoriasis / Q000453:epidemiology*; D012535:Scalp; D012737:Sex Factors
keywords: Adolescent; Child; Enfant; Infant; Nourrisson; Psoriasis