title: Chemical profile of mango (Mangifera indica L.) using electrospray ionisation mass spectrometry (ESI-MS).
abstract: Mangifera indica L., mango fruit, is consumed as a dietary supplement with purported health benefits; it is widely used in the food industry. Herein, the chemical profile of the Ubá mango at four distinct maturation stages was evaluated during the process of growth and maturity using negative-ion mode electrospray ionisation Fourier transform ion cyclotron resonance mass spectrometry (ESI(-)FT-ICR MS) and physicochemical characterisation analysis (total titratable acidity (TA), total soluble solids (TSS), TSS/TA ratio, and total polyphenolic content). Primary (organic acids and sugars) and secondary metabolites (polyphenolic compounds) were mostly identified in the third maturation stage, thus indicating the best stage for harvesting and consuming the fruit. In addition, the potential cancer chemoprevention of the secondary metabolites (phenolic extracts obtained from mango samples) was evaluated using the induction of quinone reductase activity, concluding that fruit polyphenols have the potential for cancer chemoprevention.
authors.affiliation: Laboratório de Petroleômica e Química Forense, Departamento de Química, Universidade Federal do Espírito Santo (UFES), Avenida Fernando Ferrari, 514, Goiabeiras, Vitória, ES CEP: 29075-910, Brazil.
authors.forename: Bruno G
authors.initials: BG
authors.lastname: Oliveira
authors.affiliation: Laboratório de Petroleômica e Química Forense, Departamento de Química, Universidade Federal do Espírito Santo (UFES), Avenida Fernando Ferrari, 514, Goiabeiras, Vitória, ES CEP: 29075-910, Brazil.
authors.forename: Helber B
authors.initials: HB
authors.lastname: Costa
authors.affiliation: Instituto Capixaba de Pesquisa, Assistência Técnica e Extensão Rural (INCAPER), R. Afonso Sarlo, 160 - Bento Ferreira, Vitoria, ES 29052-010, Brazil.
authors.forename: José A
authors.initials: JA
authors.lastname: Ventura
authors.affiliation: University of Hawaii at Hilo, The Daniel K. Inouye College of Pharmacy, HI, USA.
authors.forename: Tamara P
authors.initials: TP
authors.lastname: Kondratyuk
authors.affiliation: Universidade Vila Velha-UVV, Rua Comissário José Dantas de Melo, 21, Boa Vista 29102-770, Espírito Santo, Brazil.
authors.forename: Maria E S
authors.initials: MES
authors.lastname: Barroso
authors.affiliation: Laboratório de Petroleômica e Química Forense, Departamento de Química, Universidade Federal do Espírito Santo (UFES), Avenida Fernando Ferrari, 514, Goiabeiras, Vitória, ES CEP: 29075-910, Brazil.
authors.forename: Radigya M
authors.initials: RM
authors.lastname: Correia
authors.affiliation: Universidade Vila Velha-UVV, Rua Comissário José Dantas de Melo, 21, Boa Vista 29102-770, Espírito Santo, Brazil.
authors.forename: Elisângela F
authors.initials: EF
authors.lastname: Pimentel
authors.affiliation: Laboratório de Petroleômica e Química Forense, Departamento de Química, Universidade Federal do Espírito Santo (UFES), Avenida Fernando Ferrari, 514, Goiabeiras, Vitória, ES CEP: 29075-910, Brazil.
authors.forename: Fernanda E
authors.initials: FE
authors.lastname: Pinto
authors.affiliation: Universidade Vila Velha-UVV, Rua Comissário José Dantas de Melo, 21, Boa Vista 29102-770, Espírito Santo, Brazil; Instituto Federal do Espírito Santo (IFES), Av. Ministro Salgado Filho, Soteco, Vila Velha, ES 29106-010, Brazil.
authors.forename: Denise C
authors.initials: DC
authors.lastname: Endringer
authors.affiliation: Laboratório de Petroleômica e Química Forense, Departamento de Química, Universidade Federal do Espírito Santo (UFES), Avenida Fernando Ferrari, 514, Goiabeiras, Vitória, ES CEP: 29075-910, Brazil; Instituto Federal do Espírito Santo (IFES), Av. Ministro Salgado Filho, Soteco, Vila Velha, ES 29106-010, Brazil. Electronic address: wandersonromao@gmail.com.
authors.forename: Wanderson
authors.initials: W
authors.lastname: Romão
mesh_terms: D000818:Animals; D045744:Cell Line, Tumor; D055598:Chemical Phenomena; D018890:Chemoprevention; D005638:Fruit / Q000737:chemistry*; D031022:Mangifera / Q000737:chemistry*; D051379:Mice; D016660:NAD(P)H Dehydrogenase (Quinone) / Q000378:metabolism; D059808:Polyphenols / Q000032:analysis; D021241:Spectrometry, Mass, Electrospray Ionization
chemical_list: D059808:Polyphenols; D016660:NAD(P)H Dehydrogenase (Quinone)
keywords: Chemical profile; ESI(−)FT-ICR MS; Mangifera indica L.; Mango; Mass spectrometry