title: Lassa Virus Seroprevalence in Sibirilia Commune, Bougouni District, Southern Mali.
abstract: Lassa virus (LASV) is endemic to several nations in West Africa. In Mali, LASV was unknown until an exported case of Lassa fever was reported in 2009. Since that time, rodent surveys have found evidence of LASV-infected Mastomys natalensis rats in several communities in southern Mali, near the border with Côte d'Ivoire. Despite increased awareness, to date only a single case of Lassa fever has been confirmed in Mali. We conducted a survey to determine the prevalence of LASV exposure among persons in 3 villages in southern Mali where the presence of infected rodents has been documented. LASV IgG seroprevalence ranged from 14.5% to 44% per village. No sex bias was noted; however, seropositivity rates increased with participant age. These findings confirm human LASV exposure in Mali and suggest that LASV infection/Lassa fever is a potential public health concern in southern Mali.
authors.forename: Nafomon
authors.initials: N
authors.lastname: Sogoba
authors.forename: Kyle
authors.initials: K
authors.lastname: Rosenke
authors.forename: Jennifer
authors.initials: J
authors.lastname: Adjemian
authors.forename: Sory Ibrahim
authors.initials: SI
authors.lastname: Diawara
authors.forename: Ousmane
authors.initials: O
authors.lastname: Maiga
authors.forename: Moussa
authors.initials: M
authors.lastname: Keita
authors.forename: Drissa
authors.initials: D
authors.lastname: Konaté
authors.forename: Abdoul Salam
authors.initials: AS
authors.lastname: Keita
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Sissoko
authors.forename: Matt
authors.initials: M
authors.lastname: Boisen
authors.forename: Diana
authors.initials: D
authors.lastname: Nelson
authors.forename: Darin
authors.initials: D
authors.lastname: Oottamasathien
authors.forename: Molly
authors.initials: M
authors.lastname: Millett
authors.forename: Robert F
authors.initials: RF
authors.lastname: Garry
authors.forename: Luis M
authors.initials: LM
authors.lastname: Branco
authors.forename: Sékou F
authors.initials: SF
authors.lastname: Traoré
authors.forename: Seydou
authors.initials: S
authors.lastname: Doumbia
authors.forename: Heinz
authors.initials: H
authors.lastname: Feldmann
authors.forename: David
authors.initials: D
authors.lastname: Safronetz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D000914:Antibodies, Viral / Q000096:biosynthesis / Q000302:isolation & purification*; D002648:Child; D002675:Child, Preschool; D004197:Disease Reservoirs / Q000821:virology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000096:biosynthesis / Q000302:isolation & purification; D007223:Infant; D007835:Lassa Fever / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D007836:Lassa virus / Q000302:isolation & purification; D008297:Male; D008302:Mali / Q000453:epidemiology; D008875:Middle Aged; D051189:Murinae / Q000821:virology*; D051381:Rats; D012376:Rodent Diseases / Q000453:epidemiology* / Q000635:transmission / Q000821:virology; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G
keywords: Lassa fever; Lassa virus seroprevalence; West Africa; arenavirus; emerging infectious diseases; southern Mali; viral hemorrhagic fever; viruses; zoonoses