title: Laparoscopic Renal Denervation for Uncontrolled Hypertension Due to Medication Intolerance: A Case Report.
abstract: Resistant hypertension is challenging to treat, and most patients with the condition fail to achieve blood pressure control, putting them at increased risk for adverse long-term outcomes. We present the case of a 59-year-old woman with resistant hypertension due to intolerance to nearly all antihypertensive medications. After failure to achieve blood pressure control over a 5-year period, with blood pressures as high as 220/110mmHg, the patient underwent surgical treatment with bilateral laparoscopic renal denervation. Immediately after the procedure, as well as at the 1-, 3-, 9-, and 12-month follow-ups, the patient's blood pressure was reduced to the range of 120-140/80-90mmHg.
authors.affiliation: Department of Urology, Indiana University School of Medicine, Indianapolis, IN.
authors.forename: Rebecca C
authors.initials: RC
authors.lastname: Gerber
authors.affiliation: Department of Urology, Indiana University School of Medicine, Indianapolis, IN.
authors.forename: Clint D
authors.initials: CD
authors.lastname: Bahler
authors.affiliation: Department of Nephrology, Indiana University School of Medicine, Indianapolis, IN.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Kraus
authors.affiliation: Department of Urology, Indiana University School of Medicine, Indianapolis, IN. Electronic address: sundaram@iupui.edu.
authors.forename: Chandru P
authors.initials: CP
authors.lastname: Sundaram
mesh_terms: D000959:Antihypertensive Agents / Q000009:adverse effects; D005260:Female; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000601:surgery*; D007668:Kidney / Q000294:innervation*; D010535:Laparoscopy; D008875:Middle Aged; D013562:Sympathectomy / Q000379:methods*
chemical_list: D000959:Antihypertensive Agents
keywords: Blood pressure (BP); case report; circumferential dissection; kidney; laparoscopic renal denervation; resistant hypertension; sympathetic innervation