title: [Application prospect and expectation of fungistatic agents of plants in preservation of Chinese herbal medicines].
abstract: During the process of growth, harvesting, transportation, processing and storage, Chinese herbal medicines (CHMs) can be easily contaminated by fungi and their metabolites like mycotoxins, which not only express negative effects on the quality and safety of CHMs and their processed products, but also pose great threats to human health. Now, some chemical synthetic fungicides have been frequently used to control the growth of fungi and accumulation of mycotoxins in the preservation of CHMs. However, the concentration and type of chemical fungicides allowed for postharvest application are restricted due to the disadvantages of their high residual toxicity, long degradation period and pollution to the environment and so on. Therefore, it is critical to research and develop some highly effective, safe and non-toxic, natural, environment-friendly fungistatic agents from plants to prevent CHMs from being contaminated by fungi and mycotoxins. The paper reviews mycotoxins and their harmfulness, the effective compounds of fungistatic plants as well as the antifungal mechanism to provide scientific evidences for developing novel and effective fungistatic agents plants. Then, the application prospect of fungistatic agents from plants in the preservation of CHMs was discussed.
authors.forename: Yan-jun
authors.initials: YJ
authors.lastname: Li
authors.forename: Wei-jun
authors.initials: WJ
authors.lastname: Kong
authors.forename: Yi-chen
authors.initials: YC
authors.lastname: Hu
authors.forename: Lian-hua
authors.initials: LH
authors.lastname: Zhao
authors.forename: Shi-hai
authors.initials: SH
authors.lastname: Yang
authors.forename: Mei-hua
authors.initials: MH
authors.lastname: Yang
mesh_terms: D000818:Animals; D005658:Fungi / Q000187:drug effects / Q000378:metabolism; D005659:Fungicides, Industrial / Q000494:pharmacology*; D006801:Humans; D009183:Mycotoxins / Q000378:metabolism / Q000633:toxicity; D010935:Plant Diseases / Q000382:microbiology / Q000517:prevention & control*; D010936:Plant Extracts / Q000494:pharmacology*; D010946:Plants, Medicinal / Q000737:chemistry / Q000382:microbiology*; D011309:Preservation, Biological / Q000379:methods*
chemical_list: D005659:Fungicides, Industrial; D009183:Mycotoxins; D010936:Plant Extracts