title: Efficacy and Safety of Endovascular Therapy for Aortoiliac TASC D Lesions.
abstract: BACKGROUND
  Although there is increasing evidence of the effectiveness of endovascular therapy for complex aortoiliac (AI) occlusive disease, it is not universally applied to TASC D lesions.
  
  
  METHODS
  A total of 2096 patients, 2601 limbs with AI occlusive disease, were enrolled. The lesions were categorized as TASC D (395) or TASC A-C (2206), and we compared baseline data, procedure, and follow-up result between the 2 groups.
  
  
  RESULTS
  The success rate of the procedure was significantly lower in the TASC D group (91.6% vs 99.3%, P < .01), and more procedure complications occurred in the TASC D group (11.1% vs 5.2%, P < .01). The results of a 5-year follow-up revealed no significant difference in primary patency (77.9% vs 77.1%, P = .17) and major adverse cardiovascular and limb events (MACLE; 30.5% vs 33.4%, P = .42) between the 2 groups. A multivariate analysis revealed complications and critical limb ischemia are independent predictors of MACLE in the TASC D group.
  
  
  CONCLUSIONS
  The success rate of the procedure was lower in the TASC D group. Complications were more frequent in the TASC D group, and they were related to MACLE.
authors.affiliation: Department of cardiology, Saiseikai Central Hospital, Minato-ku, Tokyo, Japan k-y.suzuki@nifty.com.
authors.forename: Kenji
authors.initials: K
authors.lastname: Suzuki
authors.affiliation: Cardiovascular Center, Sendai Kousei Hospital, Sendai, Miyagi, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Mizutani
authors.affiliation: Kokura Memorial Hospital, Kitakyushu, Fukuoka, Japan.
authors.forename: Yoshimitsu
authors.initials: Y
authors.lastname: Soga
authors.affiliation: Cardiovascular Division, Kansai Rosai Hospital, Nishinomiya, Hyogo, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Iida
authors.affiliation: Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.
authors.forename: Daizo
authors.initials: D
authors.lastname: Kawasaki
authors.affiliation: Kikuna Memorial Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Yamauchi
authors.affiliation: Saiseikai Yokohama-City Eastern Hospital, Yokohama, Kanagawa, Japan.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Hirano
authors.affiliation: Tokeidai Memorial Hospital, Sapporo, Hokkaido, Japan.
authors.forename: Ryouji
authors.initials: R
authors.lastname: Koshida
authors.affiliation: Nagoya Kyoritsu Hospital, Nagoya, Aichi, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Kamoi
authors.affiliation: Kyoto University Hospital, Kyoto, Kyoto, Japan.
authors.forename: Junichi
authors.initials: J
authors.lastname: Tazaki
authors.affiliation: Sakakibara Heart Institute, Fuchu, Tokyo, Japan.
authors.forename: Michiaki
authors.initials: M
authors.lastname: Higashitani
authors.affiliation: Shin-Koga Hospital, Kurume, Fukuoka, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Shintani
authors.affiliation: Matsuyama Red Cross Hospital, Matsuyama, Ehime, Japan.
authors.forename: Terutoshi
authors.initials: T
authors.lastname: Yamaoka
authors.affiliation: Juntendo University Nerima Hospital, Nerima, Tokyo, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Okazaki
authors.affiliation: Japanese Red Cross Fukuoka Hospital, Minami-ku, Fukuoka, Japan.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Suematsu
authors.affiliation: Kanazawa Medical University Hospital, Kahoku, Ishikawa, Japan.
authors.forename: Taketsugu
authors.initials: T
authors.lastname: Tsuchiya
authors.affiliation: Shinshu University Hospital, Matsumoto, Nagano, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Miyashita
authors.affiliation: Tokai University Hospital, Isehara, Kanagawa, Japan.
authors.forename: Norihiko
authors.initials: N
authors.lastname: Shinozaki
authors.affiliation: Yamagata University Hospital, Iidanishi, Yamagata, Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Takahashi
authors.affiliation: Cardiovascular Center, Sendai Kousei Hospital, Sendai, Miyagi, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Inoue
mesh_terms: D000368:Aged; D000800:Angioplasty, Balloon / Q000009:adverse effects / Q000379:methods; D001157:Arterial Occlusive Diseases / Q000503:physiopathology / Q000601:surgery*; D057510:Endovascular Procedures / Q000009:adverse effects*; D005260:Female; D005263:Femoral Artery / Q000601:surgery; D006801:Humans; D007083:Iliac Artery / Q000503:physiopathology / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000503:physiopathology / Q000601:surgery*; D011474:Prosthesis Design; D012307:Risk Factors; D016896:Treatment Outcome; D014654:Vascular Patency / Q000502:physiology
keywords: TASC D; aortoiliac; endovascular therapy