title: Hope in the Long Road Toward the Development of a Therapeutic Human Papillomavirus Vaccine.
abstract: A pool of long synthetic peptides derived from HPV16 proteins induce objective partial or complete histologic regression of lesions in more than 50% of patients with high-grade vulvar (VuVIN3) and vaginal intraepithelial neoplasia (VaIN3). The intensity of T-cell response induced by the vaccine was correlated with clinical response. Clin Cancer Res; 22(10); 2317-9. ©2016 AACRSee related article by van Poelgeest et al., p. 2342.
authors.affiliation: INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité, Paris, France. Equipe Labellisée Ligue Contre le Cancer, Paris, France.
authors.forename: Soumaya
authors.initials: S
authors.lastname: Karaki
authors.affiliation: INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité, Paris, France. Equipe Labellisée Ligue Contre le Cancer, Paris, France. Department of Biology, Hopital Européen Georges Pompidou, AP-HP, Paris, France.
authors.forename: Helene
authors.initials: H
authors.lastname: Pere
authors.affiliation: INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité, Paris, France. Equipe Labellisée Ligue Contre le Cancer, Paris, France. Department of Biology, Hopital Européen Georges Pompidou, AP-HP, Paris, France.
authors.forename: Cecile
authors.initials: C
authors.lastname: Badoual
authors.affiliation: INSERM U970, Université Paris Descartes, Sorbonne Paris-Cité, Paris, France. Equipe Labellisée Ligue Contre le Cancer, Paris, France. Department of Biology, Hopital Européen Georges Pompidou, AP-HP, Paris, France. eric.tartour@aphp.fr.
authors.forename: Eric
authors.initials: E
authors.lastname: Tartour
mesh_terms: D000956:Antigens, Viral / Q000276:immunology; D006801:Humans; D027383:Papillomaviridae / Q000276:immunology*; D030361:Papillomavirus Infections / Q000276:immunology* / Q000517:prevention & control*; D053918:Papillomavirus Vaccines / Q000276:immunology*; D014764:Viral Proteins / Q000276:immunology
chemical_list: D000956:Antigens, Viral; D053918:Papillomavirus Vaccines; D014764:Viral Proteins