title: Reconstruction of advanced periacetabular metastatic lesions with modified Harrington procedure.
abstract: OBJECTIVE
  The purpose of this study was to assess the outcomes of patients who had been treated by a modified Harrington procedure for advanced periacetabular metastases.
  
  
  METHODS
  Between 2006 and 2013, 16 patients with a mean age of 57 years (range: 28-73 years) were treated using a modified Harrington technique. Extensive (class II/III) periacetabular defects were due to metastatic carcinoma or multiple myeloma. Surgical procedure included total hip replacement and acetabular reconstruction using threaded pins, cemented acetabular reinforcement ring, and/or polyethylene cup.
  
  
  RESULTS
  All patients improved in regard to pain and walking ability. Mean preoperative and postoperative Musculoskeletal Tumour Society (MSTS) functional scores were 52.8% (range: 33.3-73.3%) and 72% (range: 56.6-90%), respectively (p<0.05). There were 5 (31%) early or late complications requiring additional surgery. Implant survival was 75% and 37.5% at 12 and 18 months, respectively. Mean survival of the patients was 21 months (range: <1-6 years). Six remained alive, with a mean survival of 27 months (range: 18 months to 5 years).
  
  
  CONCLUSIONS
  This modified Harrington procedure can be used for reconstruction of advanced periacetabular metastatic lesions.
authors.affiliation: Marmara University Pendik Training and Research Hospital, Department of Orthopaedics and Traumatology, İstanbul, Turkey.
authors.forename: Bülent
authors.initials: B
authors.lastname: Erol
authors.affiliation: Marmara University Pendik Training and Research Hospital, Department of Orthopaedics and Traumatology, İstanbul, Turkey.
authors.forename: Ahmet Nadir
authors.initials: AN
authors.lastname: Aydemir
authors.affiliation: Marmara University Pendik Training and Research Hospital, Department of Orthopaedics and Traumatology, İstanbul, Turkey.
authors.forename: Tolga
authors.initials: T
authors.lastname: Onay
authors.affiliation: Marmara University Pendik Training and Research Hospital, Department of Orthopaedics and Traumatology, İstanbul, Turkey.
authors.forename: Mert Osman
authors.initials: MO
authors.lastname: Topkar
mesh_terms: D000077:Acetabulum / Q000601:surgery*; D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D001859:Bone Neoplasms / Q000556:secondary* / Q000628:therapy*; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D008875:Middle Aged; D010388:Pelvis / Q000000981:diagnostic imaging; D011859:Radiography; D011878:Radiotherapy; D019651:Plastic Surgery Procedures / Q000379:methods*; D014421:Turkey