title: Skin necrosis caused by prallethrin-A worldwide used insecticide.
abstract: We report a case of necrosis caused by the use of prallethrin (mosquito repellent) on the skin in a 67-year-old diabetic female patient suffering from delusions of parasitosis. Cutaneous toxicity due to pyrethroids is less known or reported, despite well-documented pyrethroid poisoning involving the gastrointestinal, respiratory, cardiac, and nervous systems. Skin irritation has been described after acute accidental exposure but, as far as we know, no data have been published on the effects of pyrethroids when applied directly to the skin.
authors.affiliation: Department of Diabetology, "Gr. T. Popa" University of Medicine and Pharmacy, Iasi, Romania. Electronic address: ginabotnariu66@gmail.com.
authors.forename: Gina
authors.initials: G
authors.lastname: Botnariu
authors.affiliation: Department of Dermatology, Nicolina Medical Center, Iasi, Romania. Electronic address: anitei_c2002@yahoo.com.
authors.forename: Cristina
authors.initials: C
authors.lastname: Birsan
authors.affiliation: Department of Cardiology, University of Medicine and Pharmacy of Tirgu Mures, Romania. Electronic address: podoleanu@me.com.
authors.forename: Cristian
authors.initials: C
authors.lastname: Podoleanu
authors.affiliation: Department of Histology, University of Medicine and Pharmacy of Tirgu Mures, Romania. Electronic address: cosmin.moldovan@outlook.com.
authors.forename: Cosmin
authors.initials: C
authors.lastname: Moldovan
authors.affiliation: Department of Pathology, University of Medicine and Pharmacy of Tirgu Mures, Romania. Electronic address: stolnicu@gmx.net.
authors.forename: Simona
authors.initials: S
authors.lastname: Stolnicu
authors.affiliation: Department of Dermatology, Nicolina Medical Center, Iasi, Romania; Department of Dermato-Physiology, Apollonia University, Iasi, Romania. Electronic address: ancachiriac@yahoo.com.
authors.forename: Anca
authors.initials: A
authors.lastname: Chiriac
mesh_terms: D000368:Aged; D005260:Female; D006801:Humans; D007302:Insect Repellents / Q000506:poisoning*; D007306:Insecticides / Q000506:poisoning*; D009336:Necrosis / Q000139:chemically induced*; D011722:Pyrethrins; D012867:Skin / Q000187:drug effects / Q000473:pathology*
chemical_list: D007302:Insect Repellents; D007306:Insecticides; D011722:Pyrethrins; C055818:d,d-T80-prallethrin
keywords: Insecticide; Pyrethroid; Skin necrosis