title: [Cortical dysgenesis with epileptic syndromes and symptomatic epilepsy in children].
abstract: Cortical dysgenesis (CD) is a frequent inherited brain malformation. CD is a key cause of epileptic syndrome in children. In this review, the author presents a current classification of CD, etiological factors of their development, including gene mutations and adverse effects of various toxins and perinatal factors. A spectrum of clinical symptoms of CD with epileptic seizures is discussed in details. A role of current MRI-regimes in the diagnosis, the management of patients and prognosis of the course of CD are highlighted.
authors.affiliation: Russian Medical Academy of Postgraduate Education, Moscow.
authors.forename: O A
authors.initials: OA
authors.lastname: Milovanova
mesh_terms: D002540:Cerebral Cortex / Q000002:abnormalities* / Q000187:drug effects; D002648:Child; D002675:Child, Preschool; D004827:Epilepsy / Q000175:diagnosis* / Q000209:etiology* / Q000235:genetics; D006801:Humans; D008279:Magnetic Resonance Imaging; D009154:Mutation; D011379:Prognosis; D013577:Syndrome