title: Deletion Variants of Middle East Respiratory Syndrome Coronavirus from Humans, Jordan, 2015.
abstract: We characterized Middle East respiratory syndrome coronaviruses from a hospital outbreak in Jordan in 2015. The viruses from Jordan were highly similar to isolates from Riyadh, Saudi Arabia, except for deletions in open reading frames 4a and 3. Transmissibility and pathogenicity of this strain remains to be determined.
authors.forename: Mart M
authors.initials: MM
authors.lastname: Lamers
authors.forename: V Stalin
authors.initials: VS
authors.lastname: Raj
authors.forename: Mah'd
authors.initials: M
authors.lastname: Shafei
authors.forename: Sami Sheikh
authors.initials: SS
authors.lastname: Ali
authors.forename: Sultan M
authors.initials: SM
authors.lastname: Abdallh
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Gazo
authors.forename: Samer
authors.initials: S
authors.lastname: Nofal
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Lu
authors.forename: Dean D
authors.initials: DD
authors.lastname: Erdman
authors.forename: Marion P
authors.initials: MP
authors.lastname: Koopmans
authors.forename: Mohammad
authors.initials: M
authors.lastname: Abdallat
authors.forename: Aktham
authors.initials: A
authors.lastname: Haddadin
authors.forename: Bart L
authors.initials: BL
authors.lastname: Haagmans
mesh_terms: D000328:Adult; D000595:Amino Acid Sequence; D001483:Base Sequence; D018352:Coronavirus Infections / Q000453:epidemiology* / Q000473:pathology / Q000821:virology; D004196:Disease Outbreaks; D005260:Female; D006761:Hospitals; D006801:Humans; D007597:Jordan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D065207:Middle East Respiratory Syndrome Coronavirus / Q000145:classification / Q000235:genetics* / Q000472:pathogenicity; D016366:Open Reading Frames; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics*; D012529:Saudi Arabia / Q000453:epidemiology; D016415:Sequence Alignment; D017384:Sequence Deletion; D014764:Viral Proteins / Q000235:genetics
chemical_list: D012367:RNA, Viral; D014764:Viral Proteins
keywords: Jordan; MERS-CoV; Middle East respiratory syndrome coronavirus; ORF3; ORF4a; coronaviruses; deletion variant; open reading frame; respiratory infections; viruses