title: Ocular Perfusion Pressure and Pulsatile Ocular Blood Flow in Normal and Systemic Hypertensive Patients.
abstract: OBJECTIVE
  Glaucomatous neuropathy can be a consequence of insufficient blood supply, increase in intraocular pressure (IOP), or other risk factors that diminish the ocular blood flow. To determine the ocular perfusion pressure (OPP) in normal and systemic hypertensive patients.
  
  
  METHODS
  One hundred and twenty-one patients were enrolled in this prospective and comparative study and underwent a complete ophthalmologic examination including slit lamp examination, Goldmann applanation tonometry, stereoscopic fundus examination, and pulsatile ocular blood flow (POBF) measurements. The OPP was calculated as being the medium systemic arterial pressure (MAP) less the IOP. Only right eye values were considered for calculations using Student's t-test.
  
  
  RESULTS
  The mean age of the patients was 57.5 years (36-78), and 68.5% were women. There was a statistically significant difference in the OPP of the normal and systemic hypertensive patients (p < 0.05). The difference in the OPP between these groups varied between 8.84 and 17.9 mm Hg.
  
  
  CONCLUSIONS
  The results of this study suggest that although the systemic hypertensive patients have a higher OPP in comparison to normal patients, this increase does not mean that they also have a higher OBF (as measured by POBF tonograph). This may be caused by chronic changes in the vascular network and in the blood hemodynamics in patients with systemic hypertension. How to cite this article: Kanadani FN, Figueiredo CR, Miranda RM, Cunha PLT, Kanadani TCM, Dorairaj S. Ocular Perfusion Pressure and Pulsatile Ocular Blood Flow in Normal and Systemic Hypertensive Patients. J Curr Glaucoma Pract 2015;9(1):16-19.
authors.affiliation: Department of Ophthalmology, Eye's Institute of Medical Science, University Hospital, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Fabio N
authors.initials: FN
authors.lastname: Kanadani
authors.affiliation: Department of Ophthalmology, Santa Casa Hospital, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Carlos R
authors.initials: CR
authors.lastname: Figueiredo
authors.affiliation: Department of Ophthalmology, Medical Science University Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Rafaela Morais
authors.initials: RM
authors.lastname: Miranda
authors.affiliation: Department of Ophthalmology, Medical Science University Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Patricia Lt
authors.initials: PL
authors.lastname: Cunha
authors.affiliation: Department of Ophthalmology, Eye's Institute of Medical Science, University Hospital, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Tereza Cristina
authors.initials: TC
authors.lastname: M Kanadani
authors.affiliation: Department of Ophthalmology, Mayo Clinic, Jacksonville Florida, USA.
authors.forename: Syril
authors.initials: S
authors.lastname: Dorairaj
keywords: Glaucoma.; Ocular perfusion pressure; Pulsatile ocular blood flow