title: Cytomegalovirus Meningitis in an Infant with Severe Combined Immunodeficiency.
abstract: A 35-day-old female with severe combined immunodeficiency developed cytomegalovirus (CMV) meningitis before undergoing hematopoietic stem cell transplantation. Strategies for timely diagnosis of neonates with congenital or acquired CMV infection and prevention of CMV acquisition in the era of universal newborn severe combined immunodeficiency screening are needed.
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH. Electronic address: claudia.vicettimiguel@nationwidechildrens.org.
authors.forename: Claudia P
authors.initials: CP
authors.lastname: Vicetti Miguel
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH.
authors.forename: Asuncion
authors.initials: A
authors.lastname: Mejias
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH.
authors.forename: Octavio
authors.initials: O
authors.lastname: Ramilo
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH.
authors.forename: Monica I
authors.initials: MI
authors.lastname: Ardura
authors.affiliation: Division of Pediatric Infectious Diseases, Department of Pediatrics, Nationwide Children's Hospital, Columbus, OH; Center for Perinatal Research, Division of Neonatology, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH.
authors.forename: Pablo J
authors.initials: PJ
authors.lastname: Sánchez
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000188:drug therapy; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D007231:Infant, Newborn; D053616:Janus Kinase 3 / Q000172:deficiency; D008587:Meningitis, Viral / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D016511:Severe Combined Immunodeficiency / Q000150:complications* / Q000628:therapy
chemical_list: D000998:Antiviral Agents; C507933:JAK3 protein, human; D053616:Janus Kinase 3
keywords: Hematopoietic stem cell transplant