title: Enantioselective [3 + 2] annulation of α-substituted allenoates with β,γ-unsaturated N-sulfonylimines catalyzed by a bifunctional dipeptide phosphine.
abstract: The first enantioselective [3 + 2] annulation of α-substituted allenoates with β,γ-unsaturated N-sulfonylimines is described. In the presence of a dipeptide phosphine catalyst, a wide range of highly functionalized cyclopentenes bearing an all-carbon quaternary center were obtained in moderate to good yields and with good to excellent enantioselectivities.
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543.
authors.forename: Huanzhen
authors.initials: H
authors.lastname: Ni
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543.
authors.forename: Weijun
authors.initials: W
authors.lastname: Yao
authors.affiliation: Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore, 117543.
authors.forename: Yixin
authors.initials: Y
authors.lastname: Lu
keywords: [3 + 2] annulation; dipeptide phosphine; enantioselective; α-substituted allenoate