title: Evaluation of Central Macular Thickness and Retinal Nerve Fiber Layer Thickness using Spectral Domain Optical Coherence Tomography in a Tertiary Care Hospital.
abstract: OBJECTIVE
  To evaluate the normative data of macular thickness and retinal nerve fiber layer thickness (RNFL) among normal subjects using spectral domain optical coherence tomography (OCT).
  
  
  METHODS
  Normal subjects presenting to a tertiary medical hospital were included in the study. All patient underwent clinical examination followed by study of macular thickness and RN FL thick ness by spectral domain Topc on OCT. The data was collected and analyzed for variations in gender and age. The data was also compared with available literature.
  
  
  RESULTS
  Total numbers of patients enrolled in the study were 154 (308 eyes). Numbers of males were 79 (158 eyes) and numbers of females were 75 (150 eyes). The mean age among males was 42.67 ± 12.15 years and mean age among females was 42.88 ± 11.73 years. Overall the mean mac ular thickness (central 1 mm zone) with SD - OCT was 241.75 ± 17.3 microns. The mean macular volume was 7.6 cu. mm ± 0.33. On analysis of the RNFL thickness, we observed that the RNFL was thickest in the inferior quadrant (138.58) followed by superior (122.30) nasal (116.32) and temporal quadrant (73.04). Gender-wise comparison of the data revealed no statistically significant difference for age, macular thickness parameters, volume and RFNL values except outer temporal thickness among males and females. No age-related difference was noted in the above parameters. On comparison with available norma tive data from India and elsewhere, we found significant variations with different machines.
  
  
  CONCLUSIONS
  The study is the first to provide normative data using SD-OCT from central India. The data from spectral domain OCT correlated well with the values obtained from similar studies with SD - OCT. Values obtained from time domain OCT machines are different and are not comparable. How to cite this article: Agarwal P, Saini VK, Gupta S, Sharma A. Evaluation of Central Macular Thickness and Retinal Nerve Fiber Layer Thickness using Spectral Domain Optical Coherence Tomography in a Tertiary Care Hospital. J Curr Glaucoma Pract 2014;8(2):75-81.
authors.affiliation: Assistant Professor, Department of Ophthalmology, People's College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
authors.forename: Prakashchand
authors.initials: P
authors.lastname: Agarwal
authors.affiliation: Professor and Head, Department of Ophthalmology, People's College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
authors.forename: V K
authors.initials: VK
authors.lastname: Saini
authors.affiliation: Professor, Department of Ophthalmology, People's College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
authors.forename: Saroj
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Senior Resident, Department of Ophthalmology, People's College of Medical Sciences and Research Centre, Bhopal, Madhya Pradesh, India.
authors.forename: Anjali
authors.initials: A
authors.lastname: Sharma
keywords: Central India.; Normative data; Spectral Domain OCT