title: Applications of Chiral Squaramides: From Asymmetric Organocatalysis to Biologically Active Compounds.
abstract: This review seeks to provide coverage on the recent advances in chiral squaramide-catalyzed asymmetric transformations and their applications in the synthesis of a variety of chiral biologically active compounds. It aims to give an overview highlighting the new reaction types and enantioenriched medicinal scaffolds developed in the last few years.
authors.affiliation: State Key Laboratory of Virology, Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, P. R. China.
authors.forename: Xin
authors.initials: X
authors.lastname: Han
authors.affiliation: State Key Laboratory of Virology, Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, P. R. China.
authors.forename: Hai-Bing
authors.initials: HB
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Virology, Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of Education Wuhan University School of Pharmaceutical Sciences, Wuhan, 430071, P. R. China.|Key Laboratory of Organofluorine Chemistry Shanghai Institute of Organic Chemistry Chinese Academy of Sciences, Shanghai, 200032, P. R. China.
authors.forename: Chune
authors.initials: C
authors.lastname: Dong
mesh_terms: D002384:Catalysis; D006801:Humans; D011803:Quinine / Q000031:analogs & derivatives* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: C000609819:squaramide; D011803:Quinine
keywords: applications; asymmetric synthesis; drug discovery; squaramides