title: Effect of Gender and Body Weight on Postprandial Glucose and Lipid Metabolism in Adults with Type 2 Diabetes.
abstract: BACKGROUND
  The magnitude of the healthcare problem of type-2-diabetes increases according to its association with several risk factors for cardiovascular diseases such as obesity and dyslipidemia.
  
  
  METHODS
  This study took place in the north-western region of Algeria. We aimed to assess the effect of body weight and gender on postprandial lipid and glucose in type-2-diabetes patients. 93 diabetic patients (age 55.65±13.81 years) were studied. Anthropometric parameters and body mass index (BMI) were measured. Fasting and postprandial (PP) glucose and lipid (total cholesterol, HDLcholesterol, LDL-cholesterol, triglycerides, apo A-I and apo B) profiles were evaluated.
  
  
  RESULTS
  There were a positive correlation between postprandial glucose and BMI in women (r2 = 0.041). Negative correlation with BMI was noticed for PP TG in both males (r2 = 0.011) and females (r2 = 0.021). A significant difference (p= 0.019) was observed for PP HDL-c in women (0.39 ± 0.10 g/L vs. men 0.33 ± 0.12 g/L) and also for PP apo A-I (women: 1.33 ± 0.27 g/L vs. men: 1.09 ± 0.34 g/L; p= 0.0003). According to gender and weight groups, our results indicated that female gender and overweight are associated with elevated PP HDL-c and PP apo A-I levels. However, obesity in women is related to high concentration of PP TG.
  
  
  CONCLUSIONS
  The present study suggests that gender difference and weight classes are important factors that contribute to determining the postprandial responses, both for glucose and lipids, in type 2 diabetic patients.
authors.affiliation: Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, Sidi-bel-Abbes, Algeria.
authors.forename: M
authors.initials: M
authors.lastname: Diaf
authors.affiliation: Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, Sidi-bel-Abbes, Algeria.
authors.forename: B M
authors.initials: BM
authors.lastname: Khaled
authors.affiliation: Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, Sidi-bel-Abbes, Algeria.
authors.forename: H H
authors.initials: HH
authors.lastname: Habib
authors.affiliation: Department of Biology, Faculty of Natural and Life Sciences, Djillali Liabes University, Sidi-bel-Abbes, Algeria.
authors.forename: S
authors.initials: S
authors.lastname: Belbraoued
mesh_terms: D000328:Adult; D000368:Aged; D000462:Algeria / Q000453:epidemiology; D001053:Apolipoproteins / Q000097:blood*; D001786:Blood Glucose / Q000032:analysis*; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D050171:Dyslipidemias / Q000097:blood / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology; D019518:Postprandial Period; D012307:Risk Factors; D012737:Sex Factors; D013223:Statistics as Topic
chemical_list: D001053:Apolipoproteins; D001786:Blood Glucose; D002784:Cholesterol
keywords: gender difference; postprandial dyslipidemia; type 2 diabetes; weight groups.