title: Conjunctival Involvement of T-Cell Lymphoma in a Patient with Mycosis Fungoides.
abstract: Background. Ocular involvement in mycosis fungoides (MF) cases occurs in one-third of patients with the eyelid being the most frequent site affected; however, conjunctival involvement is rarely reported. Herein, we report a rare case of conjunctival involvement of MF. Case Presentation. A 66-year-old man who was previously diagnosed with MF in 2010 and was treated presented in 2014 complaining of foreign body sensation and redness in both eyes. Slit lamp examination of both eyes showed erythematous conjunctival growth that extended circumferentially. Physical examination revealed erythematous skin lesions on different body parts. Conjunctival biopsy was performed and revealed a dense, highly polymorphic lymphocytic population. The immunophenotype demonstrated a neoplastic T-cell origin consistent with MF. A diagnosis of conjunctival involvement by MF was made. The conjunctiva was treated with radiotherapy resulting in tumor regression. There were no recurrences at the 6-month follow-up. Conclusion. T-cell lymphoma should be considered in patients with a history of MF presenting with conjunctival and skin lesions.
authors.affiliation: Henry C. Witelson Ocular Pathology Laboratory, McGill University, 1001 Boulevard Decarie, Montreal, QC, Canada H4A 3J1; Department of Ophthalmology, College of Medicine, King Saud University, P.O. Box 245, Riyadh 11411, Saudi Arabia.
authors.forename: Sultan S
authors.initials: SS
authors.lastname: Aldrees
authors.affiliation: Henry C. Witelson Ocular Pathology Laboratory, McGill University, 1001 Boulevard Decarie, Montreal, QC, Canada H4A 3J1.
authors.forename: Pablo
authors.initials: P
authors.lastname: Zoroquiain
authors.affiliation: Henry C. Witelson Ocular Pathology Laboratory, McGill University, 1001 Boulevard Decarie, Montreal, QC, Canada H4A 3J1.
authors.forename: Sarah A
authors.initials: SA
authors.lastname: Alghamdi
authors.affiliation: Henry C. Witelson Ocular Pathology Laboratory, McGill University, 1001 Boulevard Decarie, Montreal, QC, Canada H4A 3J1.
authors.forename: Patrick T
authors.initials: PT
authors.lastname: Logan
authors.affiliation: Department of Ophthalmology, McGill University, 5252 Boulevard de Maisonneuve Ouest, Montreal, QC, Canada H4A 3S5.
authors.forename: Sonia
authors.initials: S
authors.lastname: Callejo
authors.affiliation: Henry C. Witelson Ocular Pathology Laboratory, McGill University, 1001 Boulevard Decarie, Montreal, QC, Canada H4A 3J1; Department of Ophthalmology, McGill University, 5252 Boulevard de Maisonneuve Ouest, Montreal, QC, Canada H4A 3S5.
authors.forename: Miguel N
authors.initials: MN
authors.lastname: Burnier