title: Serosurvey of peste des petits ruminants virus in small ruminants from different agro-ecological zones of Nigeria.
abstract: Peste des petits ruminants, caused by the peste des petits ruminants virus (PPRV), is a highly contagious and economically important transboundary viral disease of domestic and wild small ruminants and a major hindrance to small-ruminant production in Nigeria. The seroprevalence and distribution of PPRV antibodies in small ruminants in rural households, farms, live animal markets and slaughter slabs across the six different agro-ecological zones of Nigeria were determined. A total of 4548 serum samples from 3489 goats and 1059 sheep were collected in 12 states. A PPRV competitive enzyme-linked immunosorbent assay was used to test the samples and the data analysed with R statistical software version 3.0.1. The study animals included all ages and both sexes. The overall prevalence estimate of sera positive for PPRV antibodies was 23.16% (n = 1018 positive samples per 4548 total samples, 95% confidence interval: 21.79% - 24.57%). There were significant differences in the seroprevalence between the states (p = 0.001). Taraba State had the highest seroprevalence of 29.51%, whilst the lowest seroprevalence of 14.52% was observed in Cross River State. There were no significant differences in the PPRV seroprevalence between male and female animals (p = 0.571), age (p = 0.323) and between species (p = 0.639). These data indicate the current seroprevalence to PPRV in the small-ruminant population in Nigeria.
authors.affiliation: Department of Veterinary Tropical Diseases, University of Pretoria, South Africa; Morbilliviruses Research Laboratory, National Veterinary Research Institute, Nigeria. womaty@gmail.com.
authors.forename: Timothy Y
authors.initials: TY
authors.lastname: Woma
authors.forename: Pius S
authors.initials: PS
authors.lastname: Ekong
authors.forename: Dauda G
authors.initials: DG
authors.lastname: Bwala
authors.forename: John O
authors.initials: JO
authors.lastname: Ibu
authors.forename: Louisa
authors.initials: L
authors.lastname: Ta'ama
authors.forename: Dyek Y
authors.initials: DY
authors.lastname: Dyek
authors.forename: Ladi
authors.initials: L
authors.lastname: Saleh
authors.forename: David
authors.initials: D
authors.lastname: Shamaki
authors.forename: Demo J U
authors.initials: DJ
authors.lastname: Kalla
authors.forename: Dalan
authors.initials: D
authors.lastname: Bailey
authors.forename: Haruna M
authors.initials: HM
authors.lastname: Kazeem
authors.forename: Melvyn
authors.initials: M
authors.lastname: Quan
mesh_terms: D000003:Abattoirs; D000822:Animal Husbandry; D000818:Animals; D000914:Antibodies, Viral; D004797:Enzyme-Linked Immunosorbent Assay / Q000662:veterinary; D005260:Female; D015511:Goat Diseases / Q000453:epidemiology* / Q000821:virology; D006041:Goats; D008297:Male; D009549:Nigeria / Q000453:epidemiology; D029021:Peste-des-Petits-Ruminants / Q000453:epidemiology* / Q000821:virology; D018107:Peste-des-petits-ruminants virus / Q000302:isolation & purification*; D015995:Prevalence; D016036:Seroepidemiologic Studies; D012756:Sheep; D012757:Sheep Diseases / Q000453:epidemiology* / Q000821:virology
chemical_list: D000914:Antibodies, Viral