title: Langerhans cell histiocytosis mimicking lichen nitidus with bone involvement.
abstract: We report the case of a 6-month-old Hispanic boy with a 4-month history of widespread pruritic hypopigmented papules mimicking lichen nitidus. The final diagnosis was multisystem non-risk-organ Langerhans cell histiocytosis (LCH), with cutaneous and multiple bone involvement. With this patient and others previously reported in the literature, we suggest an early biopsy of the hypopigmented rash in children.
authors.affiliation: Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Belén
authors.initials: B
authors.lastname: Lozano Masdemont
authors.affiliation: Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Laura
authors.initials: L
authors.lastname: Gómez-Recuero Muñoz
authors.affiliation: Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Villanueva Álvarez-Santullano
authors.affiliation: Department of Pathology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Verónica
authors.initials: V
authors.lastname: Parra Blanco
authors.affiliation: Department of Dermatology, Hospital General Universitario Gregorio Marañón, Madrid, Spain.
authors.forename: Minia
authors.initials: M
authors.lastname: Campos Domínguez
mesh_terms: D001706:Biopsy; D001847:Bone Diseases / Q000000981:diagnostic imaging / Q000209:etiology*; D003937:Diagnosis, Differential; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D007223:Infant; D017513:Lichen Nitidus / Q000000981:diagnostic imaging*; D008297:Male; D012867:Skin / Q000473:pathology
keywords: Langerhans cell histiocytosis; bone involvement; hypopigmentation; lichen nitidus