title: RNA-sequencing analysis of core binding factor AML identifies recurrent ZBTB7A mutations and defines RUNX1-CBFA2T3 fusion signature.
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada; Division of Hematology, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada;
authors.forename: Vincent-Philippe
authors.initials: VP
authors.lastname: Lavallée
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada; Department of Computer Science and Operations Research, Université de Montréal, Montréal, QC, Canada;
authors.forename: Sébastien
authors.identifier: 0000-0001-5477-1386
authors.initials: S
authors.lastname: Lemieux
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada;
authors.forename: Geneviève
authors.initials: G
authors.lastname: Boucher
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada;
authors.forename: Patrick
authors.initials: P
authors.lastname: Gendron
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada;
authors.forename: Isabel
authors.initials: I
authors.lastname: Boivin
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada;
authors.forename: Richard N
authors.initials: RN
authors.lastname: Armstrong
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada; Division of Hematology, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada; Quebec Leukemia Cell Bank, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada; and Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
authors.forename: Guy
authors.initials: G
authors.lastname: Sauvageau
authors.affiliation: The Leucegene project at Institute for Research in Immunology and Cancer, Université de Montréal, Montréal, QC, Canada; Division of Hematology, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada; Quebec Leukemia Cell Bank, Maisonneuve-Rosemont Hospital, Montréal, QC, Canada; and Department of Medicine, Faculty of Medicine, Université de Montréal, Montréal, QC, Canada.
authors.forename: Josée
authors.initials: J
authors.lastname: Hébert
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D050676:Core Binding Factor Alpha 2 Subunit / Q000235:genetics*; D004268:DNA-Binding Proteins / Q000235:genetics*; D005260:Female; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000235:genetics*; D008297:Male; D008875:Middle Aged; D009154:Mutation; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D012313:RNA / Q000235:genetics; D012097:Repressor Proteins / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics*; D059467:Transcriptome; D025521:Tumor Suppressor Proteins / Q000235:genetics*; D055815:Young Adult
chemical_list: C115744:CBFA2T3 protein, human; D050676:Core Binding Factor Alpha 2 Subunit; D004268:DNA-Binding Proteins; D015514:Oncogene Proteins, Fusion; C493728:RUNX1 protein, human; D012097:Repressor Proteins; D014157:Transcription Factors; D025521:Tumor Suppressor Proteins; C485514:ZBTB7A protein, human; D012313:RNA