title: Effect of puerarin on the expression of NMU, NPY, and POMC genes in the hypothalamus.
abstract: The hypothalamus is an important component of the nervous system, and neuropeptide Y (NPY), proopiomelanocortin (POMC), and neuromedin U (NMU) are key players in physiological regulation. Puerarin is important for nerve regulation. We investigated the effect of puerarin on the expression of NMU, NPY, and POMC genes in the hypothalamus. The results showed that the puerarin low-dose group and the other groups were significantly different (P < 0.05). However, there was no significant difference in NMU, POMC, and NPY among the groups.
authors.affiliation: College of Veterinary Medicine, Northwest A&F University, Yangling, Shanxi, China.|Key Laboratory of Animal Biochemistry and Nutrition, Ministry of Agriculture, Henan University of Animal Husbandry and Economy, Zhengzhou, Henan, China.
authors.forename: Q D
authors.initials: QD
authors.lastname: Jiang
authors.affiliation: College of Veterinary Medicine, Northwest A&F University, Yangling, Shanxi, China.
authors.forename: X P
authors.initials: XP
authors.lastname: Li
mesh_terms: D000818:Animals; D005786:Gene Expression Regulation; D007031:Hypothalamus / Q000187:drug effects / Q000378:metabolism*; D007529:Isoflavones / Q000494:pharmacology*; D009478:Neuropeptide Y / Q000187:drug effects / Q000235:genetics*; D009479:Neuropeptides / Q000187:drug effects / Q000235:genetics*; D011333:Pro-Opiomelanocortin / Q000187:drug effects / Q000235:genetics*; D051381:Rats
chemical_list: D007529:Isoflavones; D009478:Neuropeptide Y; D009479:Neuropeptides; C056900:neuromedin U; D011333:Pro-Opiomelanocortin; C033607:puerarin