title: Duration of dual anti-platelet therapy following drug eluting stents: Less Is More?
abstract: This meta-analysis suggests that abbreviated DAPT (<6 months) could be considered in patients undergoing PCI with current generation drug eluting stents (DES). Extended DAPT strategy (>1 year) may be appropriate in those patients in whom prevention of stent and non-stent-related coronary events are likely to offset the bleeding complications. Additional randomized trials are needed to evaluate the optimum duration of DAPT in patients with the latest generation DES and current antiplatelet drugs.
authors.affiliation: Lahey Hospital and Medical Center, Burlington, Massachusetts.
authors.forename: Vigyan V
authors.initials: VV
authors.lastname: Bang
authors.affiliation: Lahey Hospital and Medical Center, Burlington, Massachusetts.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Levy
mesh_terms: D001792:Blood Platelets; D004359:Drug Therapy, Combination; D054855:Drug-Eluting Stents; D006470:Hemorrhage; D006801:Humans; D062645:Percutaneous Coronary Intervention; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D015607:Stents; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D010975:Platelet Aggregation Inhibitors