title: Cytokines in the perinatal period - Part II.
abstract: A contemporary, robust immunologic explanation for common obstetric conditions remains elusive; why some pregnant women are more susceptible to developing preeclampsia or preterm labor is not completely understood. We explore the immunology behind four important and commonly encountered pregnancy-related conditions: preeclampsia, recurrent miscarriage, preterm labor and gestational diabetes. For each condition, we summarize the current understanding of cytokines implicated in the pathogenesis, discuss the impact of anesthesia and analgesia on selected cytokine profiles, and suggest potential opportunities for clinical and research interventions.
authors.affiliation: Division of Obstetric Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Anesthesiology, Pharmacology & Therapeutics, University of British Columbia, Vancouver, BC, Canada. Electronic address: antonchau1@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Chau
authors.affiliation: Division of Obstetric Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Anesthesia and Perioperative Care, San Francisco General Hospital, University of California San Francisco, San Francisco, CA, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Markley
authors.affiliation: Division of Obstetric Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Juang
authors.affiliation: Division of Obstetric Anesthesia, Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA.
authors.forename: L C
authors.initials: LC
authors.lastname: Tsen
mesh_terms: D000026:Abortion, Habitual / Q000276:immunology*; D016207:Cytokines / Q000097:blood*; D016640:Diabetes, Gestational / Q000276:immunology*; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000276:immunology*; D011247:Pregnancy; D047928:Premature Birth / Q000276:immunology*
chemical_list: D016207:Cytokines