title: [Renal elastography].
abstract: Renal elastography has become available with the development of noninvasive quantitative techniques (including shear-wave elastography), following the rapidly growing field of diagnosis and quantification of liver fibrosis, which has a demonstrated major clinical impact. Ultrasound or even magnetic resonance techniques are leaving the pure research area to reach the routine clinical use. With the increased incidence of chronic kidney disease and its specific morbidity and mortality, the noninvasive diagnosis of renal fibrosis can be of critical value. However, it is difficult to simply extend the application from one organ to the other due to a large number of anatomical and technical issues. Indeed, the kidney exhibits various features that make stiffness assessment more complex, such as the presence of various tissue types (cortex, medulla), high spatial orientation (anisotropy), local blood flow, fatty sinus with variable volume and echotexture, perirenal space with variable fatty content, and the variable depth of the organ. Furthermore, the stiffness changes of the renal parenchyma are not exclusively related to fibrosis, as renal perfusion or hydronephrosis will impact the local elasticity. Renal elastography might be able to diagnose acute or chronic obstruction, or to renal tumor or pseudotumor characterization. Today, renal elastography appears as a promising application that still requires optimization and validation, which is the contrary for liver stiffness assessment.
authors.affiliation: Université Paris Descartes, Sorbonne Paris, 12, rue de l'École-de-Médecine, 75006 Paris, France; Service de radiologie adultes, hôpital Necker-Enfants-Malades, 149, rue de Sèvres, 75743 Paris cedex 15, France; Institut Langevin, ESPCI Paris, PSL Research University, 1, rue Jussieu, 75005 Paris, France; CNRS UMR 7587, 1, rue Jussieu, 75005 Paris, France; Inserm ERL U-979, 1, rue Jussieu, 75005 Paris, France. Electronic address: jean-michel.correas@aphp.fr.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Correas
authors.affiliation: Université Paris Descartes, Sorbonne Paris, 12, rue de l'École-de-Médecine, 75006 Paris, France; Service de néphrologie-transplantation rénale adulte, hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, 149, rue de Sèvres, 75743 Paris cedex 15, France; Institut Necker-Enfants-Malades, Inserm U1151, 156, rue de Vaugirard, 75015 Paris, France.
authors.forename: Dany
authors.initials: D
authors.lastname: Anglicheau
authors.affiliation: Institut Langevin, ESPCI Paris, PSL Research University, 1, rue Jussieu, 75005 Paris, France; CNRS UMR 7587, 1, rue Jussieu, 75005 Paris, France; Inserm ERL U-979, 1, rue Jussieu, 75005 Paris, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Gennisson
authors.affiliation: Institut Langevin, ESPCI Paris, PSL Research University, 1, rue Jussieu, 75005 Paris, France; CNRS UMR 7587, 1, rue Jussieu, 75005 Paris, France; Inserm ERL U-979, 1, rue Jussieu, 75005 Paris, France.
authors.forename: Mickael
authors.initials: M
authors.lastname: Tanter
mesh_terms: D054459:Elasticity Imaging Techniques / Q000379:methods; D006801:Humans; D007668:Kidney / Q000473:pathology*; D011237:Predictive Value of Tests; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis / Q000000981:diagnostic imaging*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
keywords: Chronic kidney disease; Imagerie par ondes de cisaillement; Insuffisance rénale chronique; Renal elastography; Renal stiffness; Shear wave elastography; Élasticité rénale; Élastographie rénale