title: One-Pot Synthesis of Polysubstituted Benzenes through a N,N-dimethyl-4-aminopyridine (DMAP)-Catalyzed [4+2] Benzannulation of 1,3-Bis(sulfonyl)butadienes and γ-Substituted Allenoates.
abstract: A new strategy for the one-pot synthesis of polysubstituted benzenes through a N,N-dimethyl-4-aminopyridine (DMAP)-catalyzed [4+2] benzannulation from readily prepared 1,3-bis(sulfonyl)butadienes and γ-substituted allenoates is described. This method provides a facile, metal-free and general route to highly substituted benzenes under mild conditions in moderate-to-good yields with complete regioselectivity.
authors.affiliation: State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, 300071, China.
authors.forename: Meijia
authors.initials: M
authors.lastname: Chang
authors.affiliation: State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, 300071, China.
authors.forename: Chengzhou
authors.initials: C
authors.lastname: Wu
authors.affiliation: State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, 300071, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
authors.affiliation: State Key Laboratory and Institute of Elemento-organic Chemistry, Nankai University, Tianjin, 300071, China. hyou@nankai.edu.cn.|Collabortive Innovation Center of Chemical Science and Engineering (Tianjin), Tianjin, 300071, China. hyou@nankai.edu.cn.
authors.forename: You
authors.initials: Y
authors.lastname: Huang
mesh_terms: D000631:Aminopyridines / Q000737:chemistry*; D001565:Benzoates / Q000138:chemical synthesis*; D002070:Butadienes / Q000737:chemistry*; D002384:Catalysis; D003500:Cyclization; D008956:Models, Chemical
chemical_list: D000631:Aminopyridines; D001565:Benzoates; D002070:Butadienes
keywords: benzannulation; domino reactions; organocatalysis; polysubstituted benzenes; γ-substituted allenoates