title: In vitro Screening for Antioxidant, Antimicrobial, and Antidiabetic Properties of Some Korean Native Plants on Mt. Halla, Jeju Island.
abstract: In this study, Prunus padus, Lonicera caerulea, Berberis amurensis, and Ribes maximowiczianum, which are mainly distributed on Mt. Halla, Jeju Island, have been investigated for their antioxidant, antimicrobial, and antidiabetic activities. The methanol extracts of R. maximowiczianum leaves and P. padus branches exhibited significant and dose-dependent antioxidant activity including electron-donation ability and reducing power. To analyze the antimicrobial activity, each extract was tested by a serial two-fold dilution method against five selected gram-positive bacteria and four gram-negative bacteria, and this suggested that P. padus branches possessed the maximum antimicrobial activity against most of the gram-positive bacteria tested. In addition, the methanol extracts of P. padus branches exhibited the highest α-glucosidase inhibitory activity with an IC50 value of 1.0±0.1 μg/ml, indicating that P. padus is a promising source as a herbal medicine.
authors.affiliation: College of Agricultural, Life and Environmental Sciences, Chungbuk National University, Cheongju 361-763, Republic of Korea.
authors.forename: T K
authors.initials: TK
authors.lastname: Hyun
authors.affiliation: Research Institute for Hallasan, Jeju 690-816, Republic of Korea.
authors.forename: H C
authors.initials: HC
authors.lastname: Kim
authors.affiliation: College of Applied Life Sciences, The Research Institute for Subtropical Agriculture and Biotechnology, Jeju National University, Jeju 690-756, Republic of Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Kim
keywords: Antioxidant activity; Berberis amurensis; Lonicera caerulea; Prunus padus; Ribes maximowiczianum; antimicrobial activity; α-glucosidase inhibitory effect