title: Are premorbid abnormal personality traits associated with behavioural and psychological symptoms in dementia?
abstract: The study aims to investigate associations between behavioural and psychological symptoms of dementia (BPSD) and abnormal premorbid personality traits.
  
  
  
  Data were obtained from 217 patients with a diagnosis of probable Alzheimer's disease. Behavioural and psychological symptoms of late-onset dementia were assessed with the Neuropsychiatric Inventory. Premorbid personality traits were assessed using the Standardised Assessment of Personality. Abnormal premorbid personality traits were categorised with Diagnostic and Statistical Manual of Mental Disorders fourth edition and International Statistical Classification of Diseases and Related Health Problems-10 diagnostic criteria for personality disorders.
  
  
  
  Abnormal premorbid personality traits were associated with increased behavioural and psychological symptoms in dementia. Cluster A (solitary/paranoid) premorbid personality traits were associated with anxiety, depression and hallucinations. Cluster C (anxious/dependent) traits were associated with a syndrome of depression.
  
  
  
  The presence of Clusters A (solitary/paranoid) and C (anxious/dependent) abnormal premorbid personality traits seems to affect the expression of certain behavioural and psychological symptoms in dementia, depression in particular. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Department of Old Age Psychiatry, Godalming, Surrey, UK.
authors.forename: Jack
authors.initials: J
authors.lastname: Prior
authors.affiliation: Department of Old Age Psychiatry, Godalming, Surrey, UK.
authors.forename: Rajesh
authors.initials: R
authors.lastname: Abraham
authors.affiliation: Department of Psychology, University of Worcester, Worcester, UK.
authors.forename: Helen
authors.initials: H
authors.lastname: Nicholas
authors.affiliation: University of Surrey, Guildford, UK.
authors.forename: Tom
authors.initials: T
authors.lastname: Chan
authors.affiliation: University of Surrey, Guildford, UK.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Vanvlymen
authors.affiliation: Department of Psychiatry, University of Oxford, Oxford, UK.
authors.forename: Simon
authors.initials: S
authors.lastname: Lovestone
authors.affiliation: Department of Old Age Psychiatry, Godalming, Surrey, UK.
authors.forename: Harry
authors.initials: H
authors.lastname: Boothby
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000374:Aggression; D000544:Alzheimer Disease / Q000523:psychology; D001007:Anxiety / Q000150:complications; D001519:Behavior; D016000:Cluster Analysis; D003704:Dementia / Q000523:psychology*; D003863:Depression / Q000150:complications; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D006801:Humans; D007508:Irritable Mood; D008297:Male; D010551:Personality; D010554:Personality Disorders / Q000150:complications* / Q000523:psychology; D011618:Psychotic Disorders / Q000150:complications* / Q000523:psychology
keywords: BPSD (behavioural and psychological symptoms in dementia); Dementia; personality