title: En bloc resection of a C-1 lateral mass osteosarcoma: technical note.
abstract: Osteosarcoma is an aggressive primary bone tumor. It is currently treated with multimodality therapy including en bloc resection, which has been demonstrated to confer a survival benefit over intralesional resection. The authors present the case of an 8-year-old girl with a C-1 lateral mass osteosarcoma, which was treated with a 4-stage en bloc resection and spinal reconstruction. While technically complex, the feasibility of en bloc resection for spinal osteosarcoma should be explored in the pediatric population.
authors.affiliation: Departments of 1 Neurologic Surgery.
authors.forename: Michelle J
authors.initials: MJ
authors.lastname: Clarke
authors.affiliation: Otorhinolaryngology.
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Price
authors.affiliation: Radiology, and.
authors.forename: Harry J
authors.initials: HJ
authors.lastname: Cloft
authors.affiliation: Anesthesiology, Mayo Clinic, Rochester, Minnesota;
authors.forename: Leal G
authors.initials: LG
authors.lastname: Segura
authors.affiliation: Departments of 1 Neurologic Surgery.
authors.forename: Cindy A
authors.initials: CA
authors.lastname: Hill
authors.affiliation: Department of Pediatric Oncology, Medical College of Wisconsin, Milwaukee;
authors.forename: Meghen B
authors.initials: MB
authors.lastname: Browning
authors.affiliation: Department of Pediatric Oncology, St. Vincent Hospital, Green Bay; and.
authors.forename: Jon M
authors.initials: JM
authors.lastname: Brandt
authors.affiliation: Department of Pediatric Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Sean M
authors.initials: SM
authors.lastname: Lew
authors.affiliation: Department of Pediatric Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Foy
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D002574:Cervical Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D002648:Child; D005260:Female; D006801:Humans; D012516:Osteosarcoma / Q000000981:diagnostic imaging / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*
keywords: en bloc resection; neoadjuvant chemotherapy; oncology; osteosarcoma; primary tumor; transoral odontoidectomy