title: Diabetic Ketoacidosis with Ebstein&#039;s Anomaly in an Adult.
abstract: Ebstein&#039;s anomaly is a rare form of congenital malformation of the heart, characterized by apical displacement of the septal and posterior tricuspid valve leaflets, leading to atrialisation of the right ventricle with a variable degree of malformation and displacement of the anterior leaflet. It may not be detected until late in adolescence or adulthood. The clinical manifestations of Ebstein&#039;s anomaly vary greatly. We are reporting a case of 35-year male who presented with generalized fatigue, palpitation and effort intolerance. Laboratory investigations confirmed the diagnosis of diabetes ketosis. Transthoracic echocardiography showed severe Ebstein&#039;s anomaly with severe tricuspid regurgitation, no residual atrial septal defect, but with severe right ventricular dysfunction. Though only few studies showed the high prevalence of abnormal glucose metabolism in young adult patients with complex congenital heart disease, but Epstein&#039;s anomaly with diabetes ketosis was nowhere mentioned.
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka, India.
authors.forename: Soumya
authors.initials: S
authors.lastname: Patra
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka, India.
authors.forename: Nagamani A C
authors.initials: NA
authors.lastname: Beeresha P
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka, India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: B
authors.affiliation: Department of Cardiology, Sri Jayadeva Institute of Cardiovascular Sciences and Research, Bangalore, Karnataka, India.
authors.forename: Manjunath
authors.initials: M
authors.lastname: C N
mesh_terms: D000328:Adult; D016883:Diabetic Ketoacidosis / Q000175:diagnosis* / Q000188:drug therapy; D004232:Diuretics / Q000627:therapeutic use; D004437:Ebstein Anomaly / Q000150:complications / Q000000981:diagnostic imaging*; D004452:Echocardiography; D015150:Echocardiography, Doppler; D006333:Heart Failure / Q000150:complications; D006801:Humans; D007332:Insulin Infusion Systems; D049528:Insulin, Long-Acting / Q000627:therapeutic use; D008297:Male; D016896:Treatment Outcome; D014262:Tricuspid Valve Insufficiency / Q000000981:diagnostic imaging*; D018754:Ventricular Dysfunction / Q000000981:diagnostic imaging* / Q000188:drug therapy
chemical_list: D004232:Diuretics; D049528:Insulin, Long-Acting