title: Quantitative volumetric assessment of pulmonary involvement in patients with systemic sclerosis.
abstract: BACKGROUND
  Computed tomography (CT) is the gold standard for assessing interstitial lung disease (ILD) in patients with systemic sclerosis (SSc). In this study, we performed a quantitative calculation of ILD severity by examining the lung volume of SSc patients.
  
  
  METHODS
  The present study was performed retrospectively on 38 patients with SSc who were referred to our clinic. Patients were divided into two groups based on high-resolution computed tomography (HRCT): patients with ILD and patients without ILD.The percentage of lower lobe volume (PLLV) was calculated using HRCT. In addition, we evaluated the PLLV in all patients according to age, diffusing capacity of the lung for carbon monoxide (DLCO) and spirometric findings, and assessed the relationships among these factors.
  
  
  RESULTS
  PLLV of the right lung in patients with ILD was reduced when compared with patients without ILD (P=0.041). The PLLV of the right lung in patients with ILD was negatively correlated with age and forced vital capacity (FVC; P=0.01 and P=0.012, respectively).
  
  
  CONCLUSIONS
  The PLLV of the right lung may decrease in SSc patients with ILD. In these patients, the PLLV may be a quantitative parameter indicating damage in the lung.
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Mehmet Güli
authors.initials: MG
authors.lastname: Çetinçakmak
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Cemil
authors.initials: C
authors.lastname: Göya
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Cihad
authors.initials: C
authors.lastname: Hamidi
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Güven
authors.initials: G
authors.lastname: Tekbaş
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Abakay
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: İbrahim
authors.initials: İ
authors.lastname: Batmaz
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Hattapoğlu
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Yavuz
authors.affiliation: 1 Department of Radiology, 2 Department of Chest Disease, Medical School, Dicle University, Diyarbakir, Turkey ; 3 Department of Physical Medicine and Rehabilitation, Dicle University, Diyarbakir, Turkey ; 4 Department of Radiology, Medical School, Yüzüncüyıl University, Van, Turkey.
authors.forename: Aslan
authors.initials: A
authors.lastname: Bilici
keywords: Lung volume; high-resolution computed tomography (HRCT); pulmonary function test (PFT)