title: Counseling Is Effective for Smoking Cessation in Head and Neck Cancer Patients-A Systematic Review and Meta-Analysis.
abstract: OBJECTIVE
  The purpose of this systematic review was to describe the efficacy of smoking cessation counseling and the resulting quit rate in patients with head and neck cancer.
  
  
  METHODS
  A systematic literature search was conducted in the PubMed, Embase, and Cochrane databases. Predictor variables were smoking cessation counseling and smoking cessation interventions. The outcome was smoking cessation. Data collection and quality assessment were performed independently by 2 of the authors. Selected publications were assessed for potential risk of bias, and the level of evidence was evaluated using National Health and Medical Research Council guidelines. Review Manager 5.3 was used to conduct the meta-analysis.
  
  
  RESULTS
  Eight studies involving 1,239 patients were included (3 randomized controlled trials, 3 cohorts, and 2 case series). Smoking cessation was achieved considerably more often in patients who received smoking cessation counseling compared with those who received usual care.
  
  
  CONCLUSIONS
  This review shows that counseling supplemented with nicotine replacement therapy increases the possibility for smoking cessation in patients with head and neck cancer.
authors.affiliation: University of Southern Denmark, Odense, Denmark. Electronic address: Klemp.ingrid@gmail.com.
authors.forename: Ingrid
authors.initials: I
authors.lastname: Klemp
authors.affiliation: University of Southern Denmark, Odense, Denmark.
authors.forename: Mia
authors.initials: M
authors.lastname: Steffenssen
authors.affiliation: Surgeon, Department of Plastic and Reconstructive Surgery, Odense University Hospital, Odense, Denmark.
authors.forename: Vivi
authors.initials: V
authors.lastname: Bakholdt
authors.affiliation: Head of Research, Department of Oral and Maxillofacial Surgery, Odense University Hospital, Odense, Denmark.
authors.forename: Torben
authors.initials: T
authors.lastname: Thygesen
authors.affiliation: Professor and Head of Research, Department of Plastic and Reconstructive Surgery, Odense University Hospital, Odense, Denmark.
authors.forename: Jens Ahm
authors.initials: JA
authors.lastname: Sørensen
mesh_terms: D003376:Counseling; D006258:Head and Neck Neoplasms; D006801:Humans; D016540:Smoking Cessation