title: Evaluation of inorganic bovine bone graft in periodontal defects after third molar surgery.
abstract: OBJECTIVE
  This study evaluated the e cacy of inorganic bovine bone graft (IBB) in periodontal defect after mandibular third molar (3M) surgery.
  
  
  METHODS
  The authors conducted a split-mouth, prospective, randomized, blinded, placebo-controlled clinical trial involving 20 participants with a mean age of 21.60 ± 6.5 years who had symmetrical bilateral lower 3M randomly assigned to receive IBB or left empty (blooding clot). The clinical variables studied were probing depth and clinical attachment level (CAL) at preoperative and postoperative periods of 10, 30, and 60 days. Radiographic measures included the distance from the alveolar bone crest to the cementoenamel junction and the bone density at 30 and 60 days postsurgical procedure. For statistical analysis, we used the paired t-test at a level of signi cance of 5%.
  
  
  RESULTS
  It was observed a reduction in pocket depth and CAL in both groups, but IBB did not provide better results than blooding clot (P > 0.05). On the other hand, IBB group showed an increased in the bone density, and a decrease in the periodontal defect on the distal surface of second molar (2M) after 30 and 60 days of surgery compared to the control group (P < 0.05).
  
  
  CONCLUSIONS
  The use of inorganic bone graft (GenOx) did not enhance the probing depth after 3M removal. Although the radiographic ndings have showed an increase in bone density and a decrease in the periodontal defect on the distal surface of the 2M, we cannot recommend the use of IBB as a treatment for periodontal defect prevention after 3M removal.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Pernambuco Dental School, University of Pernambuco, Pernambuco, Brazil.
authors.forename: Daniela Guimaraes
authors.initials: DG
authors.lastname: de Melo
authors.affiliation: Department of Dentistry, Federal University of Sergipe, Sergipe, Brazil.
authors.forename: Thiago
authors.initials: T
authors.lastname: de Santana Santos
authors.affiliation: Department of Dentistry, Federal University of Pernambuco, Pernambuco, Brazil.
authors.forename: Felipe Perraro
authors.initials: FP
authors.lastname: Sehn
authors.affiliation: Department of Oral and Maxillofacial Surgery, Pernambuco Dental School, University of Pernambuco, Pernambuco, Brazil.
authors.forename: Emanuel Dias
authors.initials: ED
authors.lastname: de Oliveira E Silva
authors.affiliation: Department of Health Education, Federal University of Sergipe, Sergipe, Brazil.
authors.forename: Paulo Ricardo Saquete
authors.initials: PR
authors.lastname: Martins-Filho
authors.affiliation: Department of Oral and Maxillofacial Surgery, Pernambuco Dental School, University of Pernambuco, Pernambuco, Brazil.
authors.forename: Ana Cláudia Amorim Gomes
authors.initials: AC
authors.lastname: Dourado
keywords: Attachment loss; bone density; bovine bone mineral; periodontal defect; third molar