title: Synergistic Rhodium/Copper Catalysis: Synthesis of 1,3-Enynes and N-Aryl Enaminones.
abstract: Synergistic rhodium/copper catalysis enables new three-component coupling reactions of terminal alkynes and α-diazoketones and/or arylamines, allowing dediazotized carbene C-H insertion for the synthesis of functionalized 1,3-enynes and N-aryl enaminones with high stereoselectivity. The synthetic utility of these transformations results in subsequent C-C or/and C-N bond-forming reactions to effectively build up functional molecules with potential significance.
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou 221116, P. R. China.
authors.forename: Nan-Nan
authors.initials: NN
authors.lastname: Wang
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou 221116, P. R. China.
authors.forename: Lei-Rong
authors.initials: LR
authors.lastname: Huang
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou 221116, P. R. China.
authors.forename: Wen-Juan
authors.initials: WJ
authors.lastname: Hao
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou 221116, P. R. China.
authors.forename: Tian-Shu
authors.initials: TS
authors.lastname: Zhang
authors.affiliation: Department of Chemistry and Biochemistry, Texas Tech University , Lubbock, Texas 79409-1061, United States.|Institute of Chemistry & BioMedical Sciences, Collaborative Innovation Center of Chemistry for Life Sciences, Nanjing University , Nanjing 210093, P. R. China.
authors.forename: Guigen
authors.initials: G
authors.lastname: Li
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou 221116, P. R. China.
authors.forename: Shu-Jiang
authors.initials: SJ
authors.lastname: Tu
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu Normal University , Xuzhou 221116, P. R. China.|Department of Chemistry and Biochemistry, Texas Tech University , Lubbock, Texas 79409-1061, United States.
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003300:Copper / Q000737:chemistry*; D007659:Ketones / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure; D012238:Rhodium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D007659:Ketones; D003300:Copper; D012238:Rhodium