title: [Vitamin D level in children with bloodstream infection].
abstract: OBJECTIVE
  To investigate the difference in serum 25(OH)D level between children with bloodstream infection and healthy children.
  
  
  METHODS
  A case-control study was conducted among 60 children with bloodstream infection who were hospitalized between January 2010 and December 2013 and had positive results of two blood cultures. Meanwhile, 60 aged-matched healthy children who underwent physical examination during the same period of time were enrolled as the healthy control group. Chemiluminescence was applied to measure the serum 25(OH)D level, and the constituent ratios of children with different serum 25(OH)D levels were compared between the two groups.
  
  
  RESULTS
  The bloodstream infection group had a significantly lower serum 25(OH)D level than the healthy control group (P<0.01). Compared with the healthy control group, the bloodstream group had significantly lower constituent ratios of children with normal Vitamin D level (8% vs 35%) or vitamin D insufficiency (22% vs 43%) (P<0.05). Compared with the healthy control group, the bloodstream group had significantly higher constituent ratios of children with vitamin D deficiency (42% vs 13%) or severely vitamin D deficiency (28% vs 8%) (P<0.01).
  
  
  CONCLUSIONS
  Vitamin D insufficiency prevails among children, and children with bloodstream infection have a significantly lower serum 25(OH)D level than healthy children.
authors.affiliation: Department of Critical Care Medicine, Children's Hospital Affiliated to Capital Institute of Pediatrics, Beijing 100020, China. hong691028@aliyun.com.
authors.forename: Hong-Ri
authors.initials: HR
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.forename: Lin-Ying
authors.initials: LY
authors.lastname: Guo
authors.forename: Xiao-Dai
authors.initials: XD
authors.lastname: Cui
authors.forename: Qi
authors.initials: Q
authors.lastname: Zhang
authors.forename: Guo-Wei
authors.initials: GW
authors.lastname: Song
mesh_terms: D016022:Case-Control Studies; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D018805:Sepsis / Q000097:blood*; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood; D014808:Vitamin D Deficiency / Q000453:epidemiology
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D