title: [Rare diagnostics of infective endocarditis after kidney transplantation].
abstract: BACKGROUND
  Infective endocarditis in a patient after kidney transplantation is a serious infective complication which increases the risk of loss of the graft and also the mortality of patients. The most important predisposing factor is the immunosuppressive therapy - mainly induction immunosuppression.Material and case description: 250 patients underwent kidney transplantation throughout the period of 12 years in the Transplant Center Martin. This set of patients included 5 patients (2 %) after heart valve replacement. We present the case of a patient after kidney transplantation with development of endocarditis of the bioprosthesis of the aortic valve one month after successful kidney transplantation. Diagnostics of endocarditis by standard procedures (examination by transthoracic echocardiogram, transesophageal echocardiography, hemocultures) was unsuccessful. We rarely diagnosed endocarditis only by PET-CT examination with a consequent change of the antibiotic treatment and successful managing of this post-transplant complication.
  
  
  CONCLUSIONS
  Endocarditis after kidney transplantation is a serious complication which significantly worsens the mortality of patients. The risk of development of infective endocarditis after transplantation is also increased by induction, mainly by antithymocyte globulin. Diagnostics only by PET-CT examination is rare; however, in this case it fundamentally changed the approach to the patient and led to a successful treatment.
authors.forename: Ivana
authors.initials: I
authors.lastname: Dedinská
authors.forename: Petra
authors.initials: P
authors.lastname: Skalová
authors.forename: Michal
authors.initials: M
authors.lastname: Mokáň
authors.forename: Katarína
authors.initials: K
authors.lastname: Martiaková
authors.forename: Denisa
authors.initials: D
authors.lastname: Osinová
authors.forename: Miroslav
authors.initials: M
authors.lastname: Pindura
authors.forename: Blažej
authors.initials: B
authors.lastname: Palkoci
authors.forename: Marián
authors.initials: M
authors.lastname: Vojtko
authors.forename: Janka
authors.initials: J
authors.lastname: Hubová
authors.forename: Denisa
authors.initials: D
authors.lastname: Kadlecová
authors.forename: Ivona
authors.initials: I
authors.lastname: Lendová
authors.forename: Radovan
authors.initials: R
authors.lastname: Zacharovský
authors.forename: Filip
authors.initials: F
authors.lastname: Pekar
authors.forename: Lucia
authors.initials: L
authors.lastname: Kaliská
mesh_terms: D001021:Aortic Valve / Q000000981:diagnostic imaging* / Q000601:surgery; D001705:Bioprosthesis; D004696:Endocarditis / Q000175:diagnosis* / Q000276:immunology; D006084:Graft Rejection / Q000517:prevention & control*; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D016030:Kidney Transplantation; D064847:Multimodal Imaging; D049268:Positron-Emission Tomography; D011183:Postoperative Complications / Q000175:diagnosis* / Q000276:immunology; D016459:Prosthesis-Related Infections / Q000175:diagnosis* / Q000276:immunology; D014057:Tomography, X-Ray Computed
chemical_list: D007166:Immunosuppressive Agents