title: Rare disease relations through common genes and protein interactions.
abstract: ODCs (Orphan Disease Connections), available at http://csbg.cnb.csic.es/odcs, is a novel resource to explore potential molecular relations between rare diseases. These molecular relations have been established through the integration of disease susceptibility genes and human protein-protein interactions. The database currently contains 54,941 relations between 3032 diseases.
authors.affiliation: Escuela Politecnica Superior, Universidad Autonoma de Madrid, Madrid 28049, Spain.
authors.forename: Sara
authors.initials: S
authors.lastname: Fernandez-Novo
authors.affiliation: Computational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain.
authors.forename: Florencio
authors.initials: F
authors.lastname: Pazos
authors.affiliation: Computational Systems Biology Group, National Centre for Biotechnology (CNB-CSIC), Madrid 28049, Spain. Electronic address: monica.chagoyen@cnb.csic.es.
authors.forename: Monica
authors.initials: M
authors.lastname: Chagoyen
mesh_terms: D019992:Databases as Topic; D006801:Humans; D010641:Phenotype; D060066:Protein Interaction Maps / Q000235:genetics*; D035583:Rare Diseases / Q000235:genetics*
keywords: Biomedical databases; Disease relations; Protein interactions; Rare diseases