title: Simulation of Yeast Cooperation in 2D.
abstract: Evolution of cooperation has been an active research area in evolutionary biology in decades. An important type of cooperation is developed from group selection, when individuals form spatial groups to prevent them from foreign invasions. In this paper, we study the evolution of cooperation in a mixed population of cooperating and cheating yeast strains in 2D with the interactions among the yeast cells restricted to their small neighborhoods. We conduct a computer simulation based on a game theoretic model and show that cooperation is increased when the interactions are spatially restricted, whether the game is of a prisoner's dilemma, snow drifting, or mutual benefit type. We study the evolution of homogeneous groups of cooperators or cheaters and describe the conditions for them to sustain or expand in an opponent population. We show that under certain spatial restrictions, cooperator groups are able to sustain and expand as group sizes become large, while cheater groups fail to expand and keep them from collapse.
authors.affiliation: Department of Mathematics, Department of Statistics, Iowa State University, Ames, IA, 50011, USA. wang.1807@mbi.osu.edu.|Mathematical Biosciences Institute, The Ohio State University, Columbus, OH, 43210, USA. wang.1807@mbi.osu.edu.
authors.forename: M
authors.initials: M
authors.lastname: Wang
authors.affiliation: Department of Mathematics, Program on Bioinformatics and Computational Biology, Iowa State University, Ames, IA, 50011, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Mathematics, Program on Bioinformatics and Computational Biology, Iowa State University, Ames, IA, 50011, USA.
authors.forename: Z
authors.initials: Z
authors.lastname: Wu
mesh_terms: D000465:Algorithms; D005075:Biological Evolution; D003198:Computer Simulation; D005716:Game Theory; D055641:Mathematical Concepts; D056265:Microbial Interactions / Q000502:physiology*; D008954:Models, Biological; D009154:Mutation; D012441:Saccharomyces cerevisiae / Q000235:genetics / Q000502:physiology*; D013269:Stochastic Processes
keywords: Evolution of cooperation; Evolution of spatial groups; Evolutionary game theory; Games for yeast cooperation in 2D; Simulation of evolutionary games in 2D