title: Dural Reduction Surgery: A Treatment Option for Frontotemporal Brain Sagging Syndrome.
abstract: Frontotemporal brain sagging syndrome is a dementia associated with hypersomnolence, personality changes, and features of intracranial hypotension on magnetic resonance imaging. The literature is sparse with respect to treatment options; many patients simply worsen. We present a case in which this syndrome responded to lumbar dural reduction surgery. Postoperative magnetic resonance imaging indicated normalization of brain sagging and lumbar intrathecal pressure. Although no evidence of cerebrospinal leak was found, extremely thin dura was noted intraoperatively, suggesting that a thin and incompetent dura could result in this low-pressure syndrome. Clinicians who encounter this syndrome should consider dural reduction surgery as a treatment strategy.
authors.affiliation: 1Department of Biological Sciences,University of Alberta,Edmonton,Alberta,Canada.
authors.forename: Emily
authors.initials: E
authors.lastname: Mostofi
authors.affiliation: 3Department of Neurosurgery,Cedars-Sinai Medical Center,Los Angeles,California.
authors.forename: Wouter I
authors.initials: WI
authors.lastname: Schievink
authors.affiliation: 2Department of Medicine,University of Alberta,Edmonton,Alberta,Canada.
authors.forename: Valerie L
authors.identifier: http://orcid.org/0000-0002-0088-8666
authors.initials: VL
authors.lastname: Sim
mesh_terms: D006970:Disorders of Excessive Somnolence / Q000150:complications* / Q000000981:diagnostic imaging; D057180:Frontotemporal Dementia / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D019585:Intracranial Hypotension / Q000150:complications* / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000379:methods*; D010554:Personality Disorders / Q000150:complications* / Q000000981:diagnostic imaging
keywords: Frontotemporal Dementia; Neuroimaging; Neurosurgery