title: [The methodological approaches to the evaluation of the risk of developing pathology of the upper respiratory tract in the employees engaged in the dust-producing industries].
abstract: The objective of the present work was to develop the scientifically sound criteria for the evaluation of the occupational risks bearing in mind the high frequency of pathological changes in the ciliary epithelium of the upper respiratory tract in the employees engaged in the dust-producing industries. It was proposed to consider an increase of the SIgA level, alkaline shift in nasal secretion pH, elevation of body temperature, slowdown of the mucociliary transport, disintegration of the epithelial mucous membrane, and high frequency of its inflammatory and dystrophic changes as the criteria for early diagnostics of developing pathology of the upper respiratory tract. We have developed the method for the score-based evaluation of the risk of formation of pathological changes in the upper respiratory tract of the employees engaged in the dust-producing industries. This method can be used to enhance the effectiveness of the preventive and health-promoting measures.
authors.affiliation: All-Russian Research Institute of Railway Hygiene, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Moscow, Russsia, 125497.
authors.forename: V B
authors.initials: VB
authors.lastname: Pankova
authors.affiliation: Institute of General and Occupational Pathology, F.F. Erisman Federal Research Centre of Hygiene, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Mytishchi, Moscow region, Russia, 141014.
authors.forename: I N
authors.initials: IN
authors.lastname: Fedina
authors.forename: P V
authors.initials: PV
authors.lastname: Serebryakov
authors.affiliation: Institute of General and Occupational Pathology, F.F. Erisman Federal Research Centre of Hygiene, Russian Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing, Mytishchi, Moscow region, Russia, 141014.
authors.forename: E A
authors.initials: EA
authors.lastname: Preobrazhenskaya
authors.affiliation: ,Medical Sanitary Unit, 'Stoilensky' open joint-stock company, Belgorod region, Russia, 309517.
authors.forename: O N
authors.initials: ON
authors.lastname: Grishin
mesh_terms: D000395:Air Pollutants, Occupational / Q000009:adverse effects*; D004391:Dust; D006801:Humans; D015994:Incidence; D007221:Industry; D009784:Occupational Diseases / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D020545:Respiratory Mucosa / Q000473:pathology*; D012140:Respiratory Tract Diseases / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D012426:Russia / Q000453:epidemiology
chemical_list: D000395:Air Pollutants, Occupational; D004391:Dust