title: [A woman with a pure seminoma and a contralateral intratubular germinal neoplasm. A case report].
abstract: BACKGROUND
  Androgen insensitivity syndrome is an X-linked disorder, and is characterised by a female phenotype in a chromosomally male individual. It usually occurs in puberty with primary amenorrhoea or as an inguinal tumour in a female infant. In recent years, it is often also diagnosed in fertility clinics in adulthood.
  
  
  OBJECTIVE
  The case is presented of a pure seminoma in a woman with the reference diagnosis of inguinal hernia.
  
  
  METHODS
  A 53 year old woman, who was operated on in 2014 due to a nodule in left groin. Androgen insensitivity syndrome was corroborated, and histopathology reported it as a right testicular seminoma.
  
  
  CONCLUSIONS
  The importance of early diagnosis is discussed, highlighting the consequences of misdiagnosis, and question whether these patients have been adequately treated in the past. The risk of malignant transformation of an undescended testicle increases with age, thus gonadectomy should be performed after puberty, and in some cases hormone replacement therapy.
authors.affiliation: Servicio de Cirugía Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México. Electronic address: aherrera.incan@gmail.com.
authors.forename: Ángel
authors.initials: Á
authors.lastname: Herrera-Gómez
authors.affiliation: Servicio de Cirugía Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México.
authors.forename: Leticia
authors.initials: L
authors.lastname: García-Pérez
authors.affiliation: Servicio de Genética, Instituto Nacional de Cancerología, Ciudad de México, México.
authors.forename: Leny
authors.initials: L
authors.lastname: Gallardo-Alvarado
authors.affiliation: Servicio de Cirugía Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México.
authors.forename: David
authors.initials: D
authors.lastname: Isla-Ortiz
authors.affiliation: Servicio de Cirugía Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México.
authors.forename: Rosa A
authors.initials: RA
authors.lastname: Salcedo-Hernández
authors.affiliation: Servicio de Patología Oncológica, Instituto Nacional de Cancerología, Ciudad de México, México.
authors.forename: José
authors.initials: J
authors.lastname: Chanona-Vilchis
mesh_terms: D013734:Androgen-Insensitivity Syndrome / Q000097:blood / Q000150:complications* / Q000175:diagnosis; D014408:Biomarkers, Tumor / Q000097:blood; D006063:Chorionic Gonadotropin / Q000097:blood; D003456:Cryptorchidism / Q000150:complications*; D057210:Delayed Diagnosis; D003951:Diagnostic Errors; D004407:Dysgerminoma / Q000175:diagnosis; D055088:Early Detection of Cancer; D005260:Female; D006061:Gonadal Dysgenesis, 46,XY / Q000150:complications*; D006552:Hernia, Inguinal / Q000150:complications; D006801:Humans; D007986:Luteinizing Hormone / Q000097:blood; D008279:Magnetic Resonance Imaging; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D010051:Ovarian Neoplasms / Q000175:diagnosis; D018239:Seminoma / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D013736:Testicular Neoplasms / Q000097:blood / Q000175:diagnosis* / Q000209:etiology; D013739:Testosterone / Q000097:blood
chemical_list: D014408:Biomarkers, Tumor; D006063:Chorionic Gonadotropin; D013739:Testosterone; D007986:Luteinizing Hormone
keywords: Androgen insensitivity syndrome; Hernia inguinal; Inguinal hernia; Seminoma; Síndrome de insensibilidad a andrógenos