title: Periungual pyogenic granuloma formation in a patient with complex regional pain syndrome.
abstract: Peripheral nerve injury has been associated with the development of periungual pyogenic granuolomas (PGs). We present the case of a 39-year-old woman with an eight-month history of periungual PGs in the setting of a four-to-five year history of a traumatic inciting event that produced symptoms consistent with complex regional pain syndrome (CRPS). Although recurrent, these periungual PGs have remitted after treatment with topical timolol maleate. This case exhibits an underappreciated association between peripheral neurologic abnormalities, which include CRPS, and cutaneous abnormalities. It also presents evidence that supports the concept that PGs that are not appropriate for surgical treatments may be treated with topical timolol maleate.
authors.affiliation: New York University School of Medicine.
authors.forename: Rachel
authors.initials: R
authors.lastname: Resenstein
authors.forename: Stephen
authors.initials: S
authors.lastname: Lewellis
authors.forename: Marie
authors.initials: M
authors.lastname: Leger
mesh_terms: D000328:Adult; D020918:Complex Regional Pain Syndromes / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005260:Female; D017789:Granuloma, Pyogenic / Q000175:diagnosis / Q000209:etiology*; D006801:Humans; D012867:Skin / Q000473:pathology*