title: Pregnancy outcomes of blastocysts cultured overnight after thawing.
abstract: To compare embryo quality and outcomes of blastocysts thawed and transferred the same day with those thawed and cultured overnight before transfer.
  
  
  
  In this retrospective study, patients with infertility who underwent thawed embryo transfer (TET) the same day as thawing (0TET group) and those that received TET after embryos were thawed and cultured overnight before transfer (1TET group) were enrolled. Univariable and multivariable logistic regression were performed to detect the factors associated with the clinical pregnancy rate (CPR), implantation rate, miscarriage rate, and multiple pregnancy rate.
  
  
  
  A total of 489 patients (489 cycles) were included with 234 in the 0TET group and 255 in the 1TET group. There were no significant differences between the two groups with respect to age, body mass index (BMI), basal FSH and estradiol (E2) level, and causes of infertility (all, p > 0.05). There were no significant differences in the CPR, implantation rate, miscarriage rate, or multiple pregnancy rate between the two groups (all, p > 0.05), and this finding was irrespective of the endometrial preparation method.
  
  
  
  Pregnancy outcomes are the same for blastocysts thawed and cultured overnight 1 day before transfer and those thawed and transferred on the same day.
authors.affiliation: Reproductive Medicine Research Center, Sixth Affiliated Hospital, Sun Yat-Sen University, No. 17, Shougouling Rd., Guangzhou, 510275, People's Republic of China. congfangfc@sina.com.
authors.forename: Cong
authors.initials: C
authors.lastname: Fang
authors.affiliation: Reproductive Medicine Research Center, Sixth Affiliated Hospital, Sun Yat-Sen University, No. 17, Shougouling Rd., Guangzhou, 510275, People's Republic of China.
authors.forename: Chao-Min
authors.initials: CM
authors.lastname: Yue
authors.affiliation: Reproductive Medicine Research Center, Sixth Affiliated Hospital, Sun Yat-Sen University, No. 17, Shougouling Rd., Guangzhou, 510275, People's Republic of China.
authors.forename: Rui
authors.initials: R
authors.lastname: Huang
authors.affiliation: Reproductive Medicine Research Center, Sixth Affiliated Hospital, Sun Yat-Sen University, No. 17, Shougouling Rd., Guangzhou, 510275, People's Republic of China.
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Wei
authors.affiliation: Reproductive Medicine Research Center, Sixth Affiliated Hospital, Sun Yat-Sen University, No. 17, Shougouling Rd., Guangzhou, 510275, People's Republic of China.
authors.forename: Lei
authors.initials: L
authors.lastname: Jia
mesh_terms: D000328:Adult; D001755:Blastocyst; D015925:Cryopreservation / Q000379:methods; D010064:Embryo Implantation; D004624:Embryo Transfer / Q000379:methods*; D005260:Female; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D007247:Infertility, Female / Q000628:therapy; D011247:Pregnancy; D011256:Pregnancy Outcome; D018873:Pregnancy Rate; D011272:Pregnancy, Multiple; D012189:Retrospective Studies; D058989:Vitrification
keywords: Blastocyst culture; Embryo transfer; Freezing; In vitro fertilization; Vitrification