title: [Studies on chemical constituents of aqueous extract of Lonicera japonica flower buds].
abstract: From an aqueous extract of Lonicera japonica flower buds, sixteen compounds were isolated by a combination of various chromatographic techniques including column chromatography over macroporous resin, MCI gel, silica gel, and sephadex LH-20 and reversed-phase HPLC. Their structures were elucidated by spectroscopic data analysis as 6'-O-acetylvogeloside (1), 6'-O-acetylsecoxyloganin (2), dichlorogelignate (3), guanosinyl-(3' --> 5')-adenosine monophosphate(GpA,4) , 5'-O-methyladenosine (5), 2'-O-methyladenosine (6), adenosine (7), syringin (8), methyl 4-O-β-D-glucopyranosyl caffeate (9), (-)-dihydrophaseic acid 4'-O-β-D-glucopyranoside (10), ketologanin (11), 7α-morroniside (12), 7β-morroniside (13), kingiside (14), cryptochlorogenic acid methyl ester (15), and 6-hydroxymethyl-3-pyridinol (16). All the compounds were obtained from this plant for the first time, compounds 1 and 2 are new compounds, 3 and 5 are new natural products, and 4 is the first example of dinucleoside monophosphate isolated from a plant extract.
authors.forename: Yang
authors.initials: Y
authors.lastname: Yu
authors.forename: Wei-xia
authors.initials: WX
authors.lastname: Song
authors.forename: Qing-lan
authors.initials: QL
authors.lastname: Guo
authors.forename: Sheng
authors.initials: S
authors.lastname: Lin
authors.forename: Su-juan
authors.initials: SJ
authors.lastname: Wang
authors.forename: Yong-chun
authors.initials: YC
authors.lastname: Yang
authors.forename: Jian-gong
authors.initials: JG
authors.lastname: Shi
mesh_terms: D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry* / Q000302:isolation & purification; D035264:Flowers / Q000737:chemistry*; D031239:Lonicera / Q000737:chemistry*; D013058:Mass Spectrometry; D015394:Molecular Structure
chemical_list: D004365:Drugs, Chinese Herbal