title: Anterior Segment Biometry of the Accommodating Intraocular Lens and its Relationship With the Amplitude of Accommodation.
abstract: OBJECTIVE
  To evaluate the anterior segment biometry of the Tetraflex accommodating intraocular lens (AIOL) and the contribution of forward movement to the amplitude of accommodation (AMP).
  
  
  METHODS
  Patients who underwent phacoemulsification with implantation of Tetraflex AIOLs and control nonaccommodating intraocular lenses were imaged by custom-built, long scan depth spectral-domain optical coherence tomography at relaxed and maximal accommodative states. Anterior segment biometry was performed and correlated with the clinical manifestation including AMP.
  
  
  RESULTS
  Patients in the Tetraflex group showed better distance-corrected near visual acuity (logMAR 0.43±0.10 vs. logMAR 0.51±0.10, P<0.05) and greater AMP (1.99±0.58 diopters [D] vs. 1.59±0.45 D, P<0.05) compared with the control group. The measurement of the postoperative anterior chamber depth (ACD) during accommodation showed a forward movement of the AIOLs in 16 eyes (69.6%). Compared with the control group, a greater proportion of cases in the Tetraflex group experienced forward movement (χ test, P<0.001). The AMP in the AIOL group negatively correlated with changes in postoperative ACD during accommodation (r=-0.47, P<0.05), whereas AMP in the control group negatively correlated with postoperative pupil diameter (r=-0.57, P<0.05).
  
  
  CONCLUSIONS
  The Tetraflex AIOLs seemed to have a tendency for forward movement; however, the slight forward axial shifts of the Tetraflex AIOL during natural accommodation may not produce a clinically relevant change in optical power.
authors.affiliation: School of Ophthalmology and Optometry (L.L., Q.C., Y.Y., D.H., D.Z., A.Y., F.L., and M.S.), Wenzhou Medical University, Wenzhou, Zhejiang, China; and Department of Ophthalmology (J.W.), Bascom Palmer Eye Institute, University of Miami, Miami, FL.
authors.forename: Lin
authors.initials: L
authors.lastname: Leng
authors.forename: Qi
authors.initials: Q
authors.lastname: Chen
authors.forename: Yimin
authors.initials: Y
authors.lastname: Yuan
authors.forename: Di
authors.initials: D
authors.lastname: Hu
authors.forename: Dexi
authors.initials: D
authors.lastname: Zhu
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
authors.forename: Ayong
authors.initials: A
authors.lastname: Yu
authors.forename: Fan
authors.initials: F
authors.lastname: Lu
authors.forename: Meixiao
authors.initials: M
authors.lastname: Shen
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000368:Aged; D000869:Anterior Eye Segment / Q000502:physiology*; D001699:Biometry / Q000379:methods*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular / Q000592:standards; D008297:Male; D008875:Middle Aged; D018918:Phacoemulsification; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity