title: TREATMENT OF INFECTION AFTER TOTAL KNEE ARTHROPLASTY.
abstract: OBJECTIVE
  To identify and compare the rate of success of therapeutic modalities applied in surgeries for the treatment of infections associated with total knee arthroplasty (TKA), and to evaluate the functional outcome and pain in different therapeutic modalities by means of quality of life scores.
  
  
  METHODS
  We evaluated all patients who developed periprosthetic infection after TKA for primary or secondary osteoarthritis, in the period from January 1(st), 2008 to December 31(st), 2010.
  
  
  RESULTS
  In the study period, 29 patients with TKA had infection, and 12 of these underwent debridement and retention of the prosthesis (D+R), seven received two-stage and six one-stage exchange arthroplasties, and four patients were treated with suppressive antibiotic therapy because they could not undergo another surgical procedure.
  
  
  CONCLUSIONS
  The D+R, one-stage revision and two-stage revision success rates were 75%, 83.3%, and 100%, respectively. The best results of quality of life (QoL) and function occur in patients undergoing D+R. In contrast, the worst QoL and functional results were obtained in patients treated with two-stage revision arthroplasty. Level of Evidence II, Prognostic Studies - Investigating the Effect of a Patient Characteristic on the Outcome of Disease.
authors.affiliation: Faculdade de Medicina da Santa Casa de Misericórdia de São Paulo (SCMSP), São Paulo, SP, Brazil.
authors.forename: Ricardo de Paula Leite
authors.initials: Rde P
authors.lastname: Cury
authors.affiliation: Faculdade de Medicina da Santa Casa de Misericórdia de São Paulo (SCMSP), São Paulo, SP, Brazil.
authors.forename: Eduardo Hitoshi Tsuge
authors.initials: EH
authors.lastname: Cinagawa
authors.affiliation: Faculdade de Medicina da Santa Casa de Misericórdia de São Paulo (SCMSP), São Paulo, SP, Brazil.
authors.forename: Osmar Pedro Arbix
authors.initials: OP
authors.lastname: Camargo
authors.affiliation: Faculdade de Medicina da Santa Casa de Misericórdia de São Paulo (SCMSP), São Paulo, SP, Brazil.
authors.forename: Emerson Kiyoshi
authors.initials: EK
authors.lastname: Honda
authors.affiliation: Faculdade de Medicina da Santa Casa de Misericórdia de São Paulo (SCMSP), São Paulo, SP, Brazil.
authors.forename: Giselle Burlamaqui
authors.initials: GB
authors.lastname: Klautau
authors.affiliation: Faculdade de Medicina da Santa Casa de Misericórdia de São Paulo (SCMSP), São Paulo, SP, Brazil.
authors.forename: Mauro José Costa
authors.initials: MJ
authors.lastname: Salles
keywords: Arthroplasty; Infection; Knee prosthesis; Prosthesis retention; Prosthesis-related infections