title: Quality of Life Analysis and Smoking Correlation in Symptomatic Spine Osteoarthritis: A Nationwide Health Survey Analysis of an Elderly Population with EQ-5D.
abstract: OBJECTIVE
  To analyze quality of life in people with symptomatic spine osteoarthritis (OA) using the results of a cross-sectional, nationwide survey.
  
  
  METHODS
  This study used data from the Fifth Korean National Health and Nutrition Examination Survey (KNHANES V-5; 2010-2012). After excluding ineligible subjects, the total number of subjects in the study was 8,963, including 4,091 males and 4,872 females. All participants reported disabilities related to spine OA. Plain radiographs of the spine were taken for all participants.
  
  
  RESULTS
  Age, sex, smoking, drinking, education, and income level were significantly related to spine OA morbidity (P<0.05). OA morbidity was significantly higher in female ex-smokers (OR; 2.94, P<0.05). Quality of life (EQ-5D: L1~5) was significantly compromised in the group with spine OA compared to the group without spine OA (P<0.05). Overall, LQ 1, 2, 3, 4, and 5 domain scores were significantly higher in the group with spine OA (P<0.05). In the group with spine OA, quality of life was reduced on more than three questions for 34.3% of the group (EQ-5D: grade≥2); on two questions, for 18.5% of the group; and on one question, for 11.1% of the group. Mental stress, melancholy, and suicidal thinking were also more common in the group with spine OA (P<0.05). The group with radiographic spine OA but without symptoms did not have compromised EQ-5D scores, whereas the group with radiographic OA and symptoms showed a significantly reduced quality of life.
  
  
  CONCLUSIONS
  Quality of life was significantly reduced in the group with symptomatic spine OA in a large cross-sectional analysis. Physicians should consider quality of life in the treatment of patients with spine OA.
authors.affiliation: Department of Orthopedics, Korea University Ansan Hospital, Ansan, South Korea.
authors.forename: Jae-Young
authors.initials: JY
authors.lastname: Hong
authors.affiliation: Department of Biostatistics, College of Medicine, Catholic University, Seoul, South Korea.
authors.forename: Kyungdo
authors.initials: K
authors.lastname: Han
authors.affiliation: Department of Orthopedics, Korea University Ansan Hospital, Ansan, South Korea.
authors.forename: Dong-Hyup
authors.initials: DH
authors.lastname: Shin
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ewha Womans University Mokdong Hospital, Seoul, South Korea.
authors.forename: Eun Mi
authors.initials: EM
authors.lastname: Chun
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D005260:Female; D006306:Health Surveys; D006801:Humans; D008297:Male; D055013:Osteoarthritis, Spine / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D011788:Quality of Life; D011859:Radiography; D056910:Republic of Korea; D012648:Self Care / Q000706:statistics & numerical data; D012907:Smoking / Q000453:epidemiology; D012959:Socioeconomic Factors