title: Clinicopathologic analysis of isolated hematuria in child/adolescent and adult patients.
abstract: To our knowledge, no in-depth clinicopathologic study of isolated hematuria (IH) is currently available. To address this gap, we analyzed the clinicopathologic features of IH as it manifests in child/adolescent and adult patients. The clinical data and pathological types of 543 IH patients who underwent renal pathological examinations from January 2005 to June 2010 were retrospectively analyzed. Clinical manifestations differed among the age groups: children/adolescents exhibited the highest percentage of mesangial proliferative glomerulonephritis (41.78%), whereas adults showed the highest percentage of immunoglobulin A nephropathy (IgAN) (52.39%). In addition, the percentage of IH patients who were classified according to clinical pathology differed from that of patients who were classified according to renal pathological type. Patients with IgAN who were found to have minimal proteinuria had more severe IH. For IH patients, especially those with a small amount of proteinuria, renal biopsy should be performed as early as possible in order to develop a long-term treatment plan and prognosis evaluation.
authors.affiliation: Lu Ma, Department of Nephrology, Beidaihe Sanatorium of Beijing Military Area Command, Qinhuangdao 066100, China, tel. +86 335 5360274, fax: +86 335 5360270, e-mail: lumadoc@163.com.
authors.forename: GuangLei
authors.initials: G
authors.lastname: Chen
authors.forename: Jun
authors.initials: J
authors.lastname: Zhu
authors.forename: MingHui
authors.initials: M
authors.lastname: Song
authors.forename: Lu
authors.initials: L
authors.lastname: Ma
authors.forename: Tao
authors.initials: T
authors.lastname: Pan
authors.forename: Qi
authors.initials: Q
authors.lastname: Yang
authors.forename: WenSheng
authors.initials: W
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001706:Biopsy; D002648:Child; D002675:Child, Preschool; D005260:Female; D006417:Hematuria / Q000473:pathology*; D006801:Humans; D007223:Infant; D007668:Kidney / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D055815:Young Adult