title: [PREEMPTIVE ANALGESIA AS PART OF MULTICOMPONENT ANESTHESIA IN CHILDREN WITH OPERATIONS IN THE NASAL CAVITY AND NASOPHARYNX].
abstract: OBJECTIVE
  The article presents the results of assessing the impact of pre-emptive analgesia with lidocaine and paracetamol compared withfentanyl for postoperative pain in children undergoing surgery for nasal cavity and nasopharynx.
  
  
  METHODS
  We evaluated the incidence and severity ofpostoperative pain in 150 patients aged 3 to 17 years (ASA I-II), following operations in the nasal cavity and nasopharynx.
  
  
  RESULTS
  In pre-emptive analgesia group, patients (n = 75) experienced postoperative pain at 28% less in comparison with the control group. The severity ofpain was observed at 50% less in the intervention group which was accompanied by lower levels of cortisol. Additional analgesia during the first 2 hours after surgery there was within 15% less in a pre-emptive analgesia group when compared to the control group. Patients with multi-component of general anesthesia and local anesthetic lidocaine via a nebulizer and paracetamol i. v. were ready for extubation/removal of the laryngeal mask at 40% earlier; andfor transfer to the general department 50% sooner than patient with combined anesthesia with sevoflurane, nitrous oxide and fentanyl.
authors.forename: E V
authors.initials: EV
authors.lastname: Ivlev
authors.forename: E A
authors.initials: EA
authors.lastname: Bojko
authors.forename: E A
authors.initials: EA
authors.lastname: Ruban
authors.forename: O V
authors.initials: OV
authors.lastname: Butov
authors.forename: E V
authors.initials: EV
authors.lastname: Grigor'ev
mesh_terms: D000082:Acetaminophen / Q000008:administration & dosage / Q000627:therapeutic use; D000293:Adolescent; D000698:Analgesia / Q000379:methods*; D000768:Anesthesia, General; D000772:Anesthesia, Local; D002648:Child; D002675:Child, Preschool; D004359:Drug Therapy, Combination; D005283:Fentanyl / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage / Q000627:therapeutic use; D009296:Nasal Cavity / Q000601:surgery*; D009305:Nasopharynx / Q000601:surgery*; D010149:Postoperative Pain / Q000517:prevention & control; D011300:Preoperative Care / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D000082:Acetaminophen; D008012:Lidocaine; D005283:Fentanyl