title: The role of hormones in the pathogenesis of psoriasis vulgaris.
abstract: Psoriasis vulgaris is a chronic, common skin disease, which affects the patient's quality of life to the highest degree. Several exogenous factors and endogenous hormonal changes may act as triggers for psoriasis. The skin possesses a true endocrine system, which is very important in multiple systemic diseases. A number of conditions are associated with psoriasis, and its severity can also be influenced by hormones. Even though the sex hormones and prolactin have a major role in psoriasis pathogenicity, there are a lot of other hormones which can influence the psoriasis clinical manifestations: glucocorticoids, epinephrine, thyroid hormones, and insulin.
authors.affiliation: Department of Physiology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Iulia Ioana
authors.initials: II
authors.lastname: Roman
authors.affiliation: Department of Histology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Anne-Marie
authors.initials: AM
authors.lastname: Constantin
authors.affiliation: Department of Histology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Mihaela Elena
authors.initials: ME
authors.lastname: Marina
authors.affiliation: Department of Physiology, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania.
authors.forename: Remus Ioan
authors.initials: RI
authors.lastname: Orasan
keywords: glucocorticoids; prolactin; psoriasis vulgaris; sex hormones