title: Successful renal transplantation in a patient with cold agglutinin disease.
abstract: Cold agglutinin disease is a rare cause of acute graft loss after renal transplantation. A 71-year-old female with end stage renal failure was diagnosed to have cold agglutinin disease when investigated for recurrent clotting of hemodialysis circuits. Kidney transplantation was a major challenge due to unavoidable exposure of the transplant kidney to cold temperatures. Large volume plasma exchange given pre-transplant and infusion of warm saline prior to anastomosis resulted in successful renal transplantation with good graft function despite initial delayed graft function. This challenging case illustrates the complete removal of cold agglutinin antibodies with therapeutic large volume plasma exchange. J. Clin. Apheresis 32:56-58, 2017. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Newcastle Transplant Unit, John Hunter Hospital, New South Whales, Australia.|School of Medicine and Public Health, University of Newcastle, Newcastle, New South Whales, Australia.
authors.forename: Eswari
authors.initials: E
authors.lastname: Vilayur
authors.affiliation: Newcastle Transplant Unit, John Hunter Hospital, New South Whales, Australia.|School of Medicine and Public Health, University of Newcastle, Newcastle, New South Whales, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: Trevillian
authors.affiliation: Newcastle Transplant Unit, John Hunter Hospital, New South Whales, Australia.
authors.forename: Munish
authors.initials: M
authors.lastname: Heer
mesh_terms: D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000628:therapy*; D001323:Autoantibodies / Q000097:blood; D051799:Delayed Graft Function; D005260:Female; D006085:Graft Survival; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy; D016030:Kidney Transplantation / Q000379:methods* / Q000592:standards; D010951:Plasma Exchange / Q000379:methods
chemical_list: D001323:Autoantibodies
keywords: cold agglutinin disease; plasma exchange; renal transplantation