title: Glucose dependent insulinotropic polypeptide and dipeptidyl peptidase inhibitors: Their roles in management of type 2 diabetes mellitus.
abstract: This review paper highlights the major advances investigating the roles of glucose dependent insulinotropic polypeptide and its receptors in glucose metabolism and their potential use in management of type 2 diabetes mellitus. It also focusses on the role of dipeptidyl peptidase-4 inhibitors in the treatment of this disease. This study discussed the recent therapeutic development which have occurred in this field, and also covering the evolvement of the potential treatments for diabetes which can be discovered and implemented in the near future to design an effective therapy for diabetes and prediabetes.
authors.affiliation: School of Medicine, University of Tasmania, Hobart, Australia.
authors.forename: Ankit
authors.initials: A
authors.lastname: Gupta
authors.affiliation: School of Medicine, University of Tasmania, Hobart, Australia. Electronic address: H.AlAubaidy@utas.edu.au.
authors.forename: Hayder A
authors.initials: HA
authors.lastname: Al-Aubaidy
authors.affiliation: College of Pharmacy, Al-Qadisiya University, Iraq.
authors.forename: Bassim I
authors.initials: BI
authors.lastname: Mohammed
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D054873:Dipeptidyl-Peptidase IV Inhibitors / Q000627:therapeutic use*; D005749:Gastric Inhibitory Polypeptide / Q000627:therapeutic use*; D006801:Humans; D054795:Incretins / Q000627:therapeutic use*; D008954:Models, Biological
chemical_list: D054873:Dipeptidyl-Peptidase IV Inhibitors; D054795:Incretins; D005749:Gastric Inhibitory Polypeptide
keywords: Dipeptidyl peptidase-4 inhibitors; Glucose dependent insulinotropic polypeptide; Type 2 diabetes mellitus