title: Predictors of Hospitalization in Patients With Transient Ischemic Attack or Minor Ischemic Stroke.
abstract: BACKGROUND
  Transient ischemic attack (TIA) and minor stroke are associated with a substantial risk of subsequent stroke; however, there is uncertainty about whether such patients require admission to hospital for their initial management. We used data from a clinical stroke registry to determine the frequency and predictors of hospitalization for TIA or minor stroke across the province of Ontario, Canada.
  
  
  METHODS
  The Ontario Stroke Registry collects information on a population-based sample of all patients seen in the emergency department with acute stroke or TIA in Ontario. We identified patients with minor ischemic stroke or TIA included in the registry between April 1, 2008, and March 31, 2011, and used multivariable analyses to evaluate predictors of hospitalization.
  
  
  RESULTS
  Our study sample included 8540 patients with minor ischemic stroke or TIA, 47.2% of whom were admitted to hospital, with a range of 37.6% to 70.3% across Ontario's 14 local health integration network regions. Key predictors of admission were preadmission disability, vascular risk factors, presentation with weakness, speech disturbance or prolonged/persistent symptoms, arrival by ambulance, and presentation on a weekend or during periods of emergency department overcrowding.
  
  
  CONCLUSIONS
  More than one-half of patients with minor stroke or TIA were not admitted to the hospital, and there were wide regional variations in admission patterns. Additional work is needed to provide guidance to health care workers around when to admit such patients and to determine whether discharged patients are receiving appropriate follow-up care.
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Moira K
authors.initials: MK
authors.lastname: Kapral
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Ruth
authors.initials: R
authors.lastname: Hall
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Jiming
authors.initials: J
authors.lastname: Fang
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Austin
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Frank L
authors.initials: FL
authors.lastname: Silver
authors.affiliation: 2Department of Medicine,University of Toronto,Toronto,Canada.
authors.forename: Leanne K
authors.initials: LK
authors.lastname: Casaubon
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: David J
authors.initials: DJ
authors.lastname: Gladstone
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Melissa
authors.initials: M
authors.lastname: Stamplecoski
authors.affiliation: 1Institute for Clinical Evaluative Sciences,Toronto,Canada.
authors.forename: Jack V
authors.initials: JV
authors.lastname: Tu
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D004632:Emergency Medical Services / Q000706:statistics & numerical data; D004636:Emergency Service, Hospital / Q000706:statistics & numerical data; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000150:complications* / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D009864:Ontario; D011237:Predictive Value of Tests; D012042:Registries; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology / Q000209:etiology* / Q000628:therapy*
keywords: Health Services Research; TIA; hospitalization; registries; stroke; transient ischemic attack