title: MITF Drives a Reversible Drug-Tolerant State in Melanoma.
abstract: PAX3-mediated upregulation of MITF promotes mutation-independent tolerance to MAPK inhibition.
mesh_terms: D045744:Cell Line, Tumor; D006801:Humans; D008545:Melanoma; D051739:Microphthalmia-Associated Transcription Factor / Q000235:genetics*; D009154:Mutation; D000072041:PAX3 Transcription Factor; D051761:Paired Box Transcription Factors / Q000235:genetics*
chemical_list: D051739:Microphthalmia-Associated Transcription Factor; D000072041:PAX3 Transcription Factor; D051761:Paired Box Transcription Factors