title: Complementary Metal-Oxide-Semiconductor Integrated Carbon Nanotube Arrays: Toward Wide-Bandwidth Single-Molecule Sensing Systems.
abstract: There is strong interest in realizing genomic molecular diagnostic platforms that are label-free, electronic, and single-molecule. One attractive transducer for such efforts is the single-molecule field-effect transistor (smFET), capable of detecting a single electronic charge and realized with a point-functionalized exposed-gate one-dimensional carbon nanotube field-effect device. In this work, smFETs are integrated directly onto a custom complementary metal-oxide-semiconductor chip, which results in an array of up to 6000 devices delivering a measurement bandwidth of 1 MHz. In a first exploitation of these high-bandwidth measurement capabilities, point functionalization through electrochemical oxidation of the devices is observed with microsecond temporal resolution, which reveals complex reaction pathways with resolvable scattering signatures. High-rate random telegraph noise is detected in certain oxidized devices, further illustrating the measurement capabilities of the platform.
authors.affiliation: Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.
authors.forename: Steven B
authors.initials: SB
authors.lastname: Warren
authors.affiliation: Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.
authors.forename: Sefi
authors.initials: S
authors.lastname: Vernick
authors.affiliation: Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.
authors.forename: Ethan
authors.initials: E
authors.lastname: Romano
authors.affiliation: Department of Electrical Engineering, Columbia University , New York, New York 10027, United States.
authors.forename: Kenneth L
authors.initials: KL
authors.lastname: Shepard
mesh_terms: D008670:Metals / Q000737:chemistry*; D037742:Nanotubes, Carbon / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry; D012666:Semiconductors
chemical_list: D008670:Metals; D037742:Nanotubes, Carbon; D010087:Oxides
keywords: CMOS; Single-molecule; carbon nanotube; electrochemical oxidation; random telegraph noise