title: [Nutritional therapy of gout].
abstract: Nutrition and nutritional behaviours have been found to play a major role in the development of gout. Studies show that body mass index (BMI), as well as excessive intake of alcoholic beverages, meat, soft drinks and fruit juices increase the risk of developing gout. Similarly, dairy products and coffee have been seen to decrease the risk of hyperuricemia and gout, as they increase the excretion of uric acid. Flares of gout are often caused by large meals and high alcohol consumption. Each additional intake of meat portion per day increases the risk of gout by 21 %. Taking total alcohol consumption into account, the risk of gout increases after one to two standard drinks. In contrast to previous assumptions purine-rich plant foods like legumes and vegetables do not increase the risk of gout. The current dietary guidelines take into account nutritional factors, which not only consider purine intake, but also their endogenous production and their influence on renal excretion. A balanced diet based on the Swiss healthy eating guideline pyramid as well as the Mediterranean diet is appropriate for this patient population. The treatment of gout is multi-faceted, since this patient population presents other comorbidities such as obesity, diabetes mellitus, dyslipidemia and hypertension. Collectively, these risk factors are diet dependent and require a treatment strategy that is centered on modifying one's nutrition and nutritional behaviours. The aim of such therapy is to educate the patient as well as treat the accompanying comorbidities with the goal of decreasing serum uric acid values. Motivated patients require consultation and follow-up care in order to be able to actively decrease the serum uric acid.
authors.affiliation: 1 Ernährungsberatung, Universitätsspital Basel.
authors.forename: Beate
authors.initials: B
authors.lastname: Nickolai
authors.affiliation: 1 Ernährungsberatung, Universitätsspital Basel.
authors.forename: Caroline
authors.initials: C
authors.lastname: Kiss
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects; D003131:Combined Modality Therapy; D038441:Diet, Mediterranean; D005247:Feeding Behavior; D006073:Gout / Q000178:diet therapy* / Q000209:etiology; D006801:Humans; D018673:Nutrition Policy; D013557:Switzerland; D014527:Uric Acid / Q000097:blood
chemical_list: D014527:Uric Acid