title: Characteristics and Predictors of Mortality in Patients With Cardiovascular Shock in Japan　- Results From the Japanese Circulation Society Cardiovascular Shock Registry.
abstract: BACKGROUND
  There are little data about cardiovascular shock caused by various diseases. We evaluated the characteristics and predictors of 30-day mortality in patients with cardiovascular shock in Japan.
  
  
  RESULTS
  The Japanese Circulation Society Cardiovascular Shock registry was a prospective, observational, multicenter, cohort study. Between May 2012 and June 2014, 979 patients with cardiovascular shock were analyzed. The primary endpoint was 30-day all-cause mortality. The mean systolic blood pressure on hospital arrival was 78±18 mmHg. The main causes of shock were acute coronary syndrome (51.0%), non-ischemic arrhythmia (16.4%), and aortic disease (14.9%). The 30-day all-cause mortality was 34.3%. After adjustment for independent predictors of 30-day mortality, the odds ratios for systolic blood pressure (per 10-mmHg decrease), consciousness disturbance, congestive heart failure, out-of-hospital cardiac arrest, estimated glomerular filtration rate (per 10-ml/min/1.73 m(2)decrease), and causes of shock (non-ischemic arrhythmia, aortic disease, and myocarditis) were 1.15 (95% confidence interval [CI], 1.08-1.22), 2.62 (95% CI, 1.80-3.82), 2.58 (95% CI, 1.67-3.99), 1.62 (95% CI, 1.05-2.51), 1.20 (95% CI, 1.10-1.30), and 0.48 (95% CI, 0.30-0.77), 3.98 (95% CI, 2.32-6.81), and 3.25 (95% CI, 1.20-8.84), respectively.
  
  
  CONCLUSIONS
  The 30-day mortality for cardiovascular shock was still high at 34%. Primary predictors of mortality were cardiorenal function on hospital arrival and shock etiology.
authors.affiliation: JCS Shock Registry Scientific Committee.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Ueki
authors.forename: Masahiro
authors.initials: M
authors.lastname: Mohri
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Matoba
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Tsujita
authors.forename: Masao
authors.initials: M
authors.lastname: Yamasaki
authors.forename: Eizo
authors.initials: E
authors.lastname: Tachibana
authors.forename: Naohiro
authors.initials: N
authors.lastname: Yonemoto
authors.forename: Ken
authors.initials: K
authors.lastname: Nagao
mesh_terms: D054058:Acute Coronary Syndrome / Q000150:complications / Q000401:mortality / Q000503:physiopathology; D000368:Aged; D000369:Aged, 80 and over; D001018:Aortic Diseases / Q000150:complications / Q000401:mortality / Q000503:physiopathology; D001145:Arrhythmias, Cardiac / Q000150:complications / Q000401:mortality / Q000503:physiopathology; D044466:Asian People; D001775:Blood Circulation; D001794:Blood Pressure; D006801:Humans; D007564:Japan / Q000453:epidemiology; D008875:Middle Aged; D009205:Myocarditis / Q000150:complications / Q000401:mortality / Q000503:physiopathology; D058687:Out-of-Hospital Cardiac Arrest / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D011446:Prospective Studies; D012042:Registries; D012770:Shock, Cardiogenic / Q000209:etiology / Q000401:mortality / Q000503:physiopathology; D012955:Societies, Medical