title: Treatment of Non-infectious Uveitic Macular Edema with the Intravitreal Dexamethasone Implant.
abstract: OBJECTIVE
  To describe the clinical outcome of phakic eyes with macular edema (ME) due to non-infectious uveitis treated with a dexamethasone intravitreal implant.
  
  
  METHODS
  A retrospective analysis of 41 eyes treated with a total of 58 dexamethasone intravitreal implants was conducted. Best corrected visual acuity (BCVA), central retinal thickness (CRT) and complications data were collected.
  
  
  RESULTS
  One month after the first implant, even as CRT improved significantly in most eyes (p<0.001), 31.7% showed no improvement in BCVA. At 6 months post-implantation, CRT and BCVA had deteriorated in up to 70% of patients. Thirteen eyes were re-implanted, with a similar effect to that of the first implant. Ocular hypertension developed in 36.2% of eyes, and three eyes had cataract surgery, all in eyes with repeated implants.
  
  
  CONCLUSIONS
  The dexamethasone intravitreal implant can be safely used to treat ME due to non-infectious uveitis, but with a limited and short effect on BCVA.
authors.affiliation: a Département Hospitalo-Universitaire Vision and Handicaps 'ViewMaintain' , Pitié-Salpêtrière University Hospital , Paris , France.|b Department of Ophthalmology , Hospital Garcia de Orta E.P.E , Almada , Portugal.
authors.forename: João
authors.initials: J
authors.lastname: Nobre-Cardoso
authors.affiliation: a Département Hospitalo-Universitaire Vision and Handicaps 'ViewMaintain' , Pitié-Salpêtrière University Hospital , Paris , France.
authors.forename: Emmanuelle
authors.initials: E
authors.lastname: Champion
authors.affiliation: a Département Hospitalo-Universitaire Vision and Handicaps 'ViewMaintain' , Pitié-Salpêtrière University Hospital , Paris , France.
authors.forename: Adil
authors.initials: A
authors.lastname: Darugar
authors.affiliation: a Département Hospitalo-Universitaire Vision and Handicaps 'ViewMaintain' , Pitié-Salpêtrière University Hospital , Paris , France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Fel
authors.affiliation: a Département Hospitalo-Universitaire Vision and Handicaps 'ViewMaintain' , Pitié-Salpêtrière University Hospital , Paris , France.
authors.forename: Phuc
authors.initials: P
authors.lastname: Lehoang
authors.affiliation: a Département Hospitalo-Universitaire Vision and Handicaps 'ViewMaintain' , Pitié-Salpêtrière University Hospital , Paris , France.
authors.forename: Bahram
authors.initials: B
authors.lastname: Bodaghi
mesh_terms: D003907:Dexamethasone / Q000008:administration & dosage*; D004343:Drug Implants; D005260:Female; D005500:Follow-Up Studies; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D058449:Intravitreal Injections; D008269:Macular Edema / Q000188:drug therapy* / Q000209:etiology / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D012160:Retina / Q000473:pathology; D019233:Retreatment; D012189:Retrospective Studies; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology; D014822:Vitreous Body / Q000187:drug effects
chemical_list: D004343:Drug Implants; D005938:Glucocorticoids; D003907:Dexamethasone
keywords: Central retinal thickness; dexamethasone intravitreal implant; macular edema; uveitis; visual acuity