title: [Application of big data analyses for musculoskeletal cell differentiation].
abstract: Next generation sequencer has strongly progress big data analyses in life science. Among various kinds of sequencing data sets, epigenetic platform has just been important key to clarify the questions on broad and detail phenomenon in various forms of life. In this report, it is introduced that the research on identification of novel transcription factors in osteoclastogenesis using DNase-seq. Big data on musculoskeletal research will be organized by IFMRS and is getting more crucial.
authors.affiliation: Division of Integrative Pathophysiology, Proteo-Science Center,Department of Pathophysiology, Graduate School of Medicine,Division of Experimental Animal Research, Advanced Research Support Center,Ehime University, Japan.
authors.forename: Yuuki
authors.initials: Y
authors.lastname: Imai
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D042002:Chromatin Assembly and Disassembly; D044127:Epigenesis, Genetic; D020869:Gene Expression Profiling; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D018482:Muscle, Skeletal / Q000166:cytology* / Q000378:metabolism; D020543:Proteome / Q000737:chemistry; D017422:Sequence Analysis, DNA
chemical_list: D020543:Proteome