title: Acute arterial ischemia in a patient with polyarthritis.
abstract: Cryoglobulins are immunoglobulins that precipitate at cold temperatures. Their presence can be related to a type of vasculitis referred to as cryoglobulinemia. This condition, especially mixed cryoglobulinemia, has been associated with viral infections like hepatitis C virus in 60%-90% of cases, but it has also been reported in relation to connective tissue diseases, usually resulting in a more severe course. We describe the case of a patient with seronegative polyarthritis who developed acute arterial ischemia in association with cryoglobulinemia, with a good response to rituximab therapy.
authors.affiliation: Unidad de Reumatología, Hospital General de Villarrobledo, Albacete, España. Electronic address: sandrasoromarin@hotmail.com.
authors.forename: Sandra
authors.initials: S
authors.lastname: Soro Marín
authors.affiliation: Sección de Reumatología, Complejo Hospitalario Universitario de Albacete, Albacete, España.
authors.forename: Enrique
authors.initials: E
authors.lastname: Júdez Navarro
authors.affiliation: Servicio de Medicina Interna, Complejo Hospitalario Universitario de Albacete, Albacete, España.
authors.forename: Antonio Salvador
authors.initials: AS
authors.lastname: Alamillo Sanz
authors.affiliation: Sección de Reumatología, Complejo Hospitalario Universitario de Albacete, Albacete, España.
authors.forename: Ginés
authors.initials: G
authors.lastname: Sánchez Nievas
mesh_terms: D000328:Adult; D001157:Arterial Occlusive Diseases / Q000175:diagnosis / Q000209:etiology*; D001168:Arthritis / Q000209:etiology*; D003449:Cryoglobulinemia / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D006225:Hand / Q000098:blood supply*; D006801:Humans; D007511:Ischemia / Q000175:diagnosis / Q000209:etiology*; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000175:diagnosis*; D016491:Peripheral Vascular Diseases / Q000175:diagnosis / Q000209:etiology*; D017534:Radial Artery
keywords: Acute arterial ischemia; Crioglobulinemia; Cryoglobulinemia; Isquemia arterial aguda; Lupus eritematoso sistémico; Rituximab; Systemic lupus erythematosus