title: Multi-scale patch and multi-modality atlases for whole heart segmentation of MRI.
abstract: A whole heart segmentation (WHS) method is presented for cardiac MRI. This segmentation method employs multi-modality atlases from MRI and CT and adopts a new label fusion algorithm which is based on the proposed multi-scale patch (MSP) strategy and a new global atlas ranking scheme. MSP, developed from the scale-space theory, uses the information of multi-scale images and provides different levels of the structural information of images for multi-level local atlas ranking. Both the local and global atlas ranking steps use the information theoretic measures to compute the similarity between the target image and the atlases from multiple modalities. The proposed segmentation scheme was evaluated on a set of data involving 20 cardiac MRI and 20 CT images. Our proposed algorithm demonstrated a promising performance, yielding a mean WHS Dice score of 0.899 ± 0.0340, Jaccard index of 0.818 ± 0.0549, and surface distance error of 1.09 ± 1.11 mm for the 20 MRI data. The average runtime for the proposed label fusion was 12.58 min.
authors.affiliation: SJTU-CU ICRC, Department of Engineering Mechanics, School of Naval Architecture, Ocean and Civil Engineering, Shanghai Jiao Tong University, P R China; Collaborative Innovation Center for Advanced Ship and Deep-Sea Exploration (CISSE), Shanghai 200240, P R China. Electronic address: zhuangxiahai@sjtu.edu.cn.
authors.forename: Xiahai
authors.initials: X
authors.lastname: Zhuang
authors.affiliation: Department of Statistics, School of Management, Fudan University, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Shen
mesh_terms: D000465:Algorithms; D006321:Heart / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D006801:Humans; D007089:Image Enhancement; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D064847:Multimodal Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013382:Subtraction Technique; D014057:Tomography, X-Ray Computed
keywords: Local atlas ranking; Multi-modality atlas; Multi-scale patch; Whole heart segmentation