title: [Prevalence of HPV DNA among male sexual partners of women diagnosed with CIN and early invasive cervical cancer].
abstract: Human Papilloma Virus (HPV) infection is the most common sexually transmitted disease. Chronic HPV infection is indispensable for development of cervical intraepithelial neoplasia and cervical cancer. First data stating that HPV transmission among heterosexual partners is very common appeared in last years. The aim of this study was to estimate the HPV infection prevalence among male sexual partners of women diagnosed with subclinical HPV infection, cervical intraepithelial neoplasia and early invasive cervical cancer. The study was conducted among 289 women aged 25-60 diagnosed with CIN and cervical cancer stage IA; control group consisted of 44 women aged 28-56 HPV testing using the material from retroglandular sulcus was conducted among male sexual partners of women from the study group. Testing was performed with HC2 method. In the study group, HPV infection was stated in 218 (75.43%) women and in 6 (13.63%) in control group. HPV DNA was present in 148 (51.21%) men--sexual partners of women from the study group and only 1 (2.27%) from control group. Additionally, HPV types of high and low oncogenic potential were analyzed with regard to histological diagnosis (SPI, CIN, early invasive cervical cancer). As the analysis shows, HPV infection of male sexual partners of women diagnosed with SPI and CIN is relatively high (9.09-93.33%).
authors.forename: Jacek
authors.initials: J
authors.lastname: Drabina
authors.forename: Hubert
authors.initials: H
authors.lastname: Huras
authors.forename: Tomasz
authors.initials: T
authors.lastname: Basta
authors.forename: Ewa
authors.initials: E
authors.lastname: Posadzka
authors.forename: Wioletta
authors.initials: W
authors.lastname: Hosiawa
authors.forename: Marcin
authors.initials: M
authors.lastname: Jabłoński
authors.forename: Joanna
authors.initials: J
authors.lastname: Streb
authors.forename: Robert
authors.initials: R
authors.lastname: Jach
mesh_terms: D000328:Adult; D004279:DNA, Viral / Q000032:analysis*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000235:genetics*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology; D015995:Prevalence; D012747:Sexual Partners; D002583:Uterine Cervical Neoplasms; D002578:Uterine Cervical Dysplasia
chemical_list: D004279:DNA, Viral