title: Quantitative evaluation of left ventricular volume and function in middle-aged healthy chinese people with 3 Tesla MRI.
abstract: To quantitatively investigate left ventricular volume and function in middle-aged healthy subjects.
  
  
  
  Ninety healthy volunteers underwent cardiac 3 Tesla MRI. The left ventricular end-diastolic volume (EDV) and end-systolic volume (ESV), stroke volume (SV), ejection fraction (EF), cardiac output (CO), myocardial mass (MM), and their normalized indices (EDVI, ESVI, SVI, CI, and MI, respectively) after corrected with the body surface area (BSA) were analyzed and compared at different ages.
  
  
  
  All subjects had successfully completed the 3-Tesla cardiac MR. Females had significantly smaller EDV (110.5 ± 9.2 versus 125.7 ± 8.3 mL), ESV (36.1 ± 3.5 versus 41.5 ± 3.8 mL), SV (74.3 ± 6.3 versus 84.2 ± 6.7 mL), CO (5.4 ± 0.8 versus 5.8 ± 0.9 l/min) and MM (73.0 ± 10.5 versus 94.8 ± 10.6 g) than males (P < 0.05). The EF had no significant (P = 0.47) difference between genders (67.3 ± 1.7 percent in females versus 66.9 ± 2.4 percent in males). After normalization with BSA, no significant (P > 0.05) difference was detected between the genders in EDVI (71.2 ± 4.3 versus 71.1 ± 4.2 mL/m2, P = 0.882), ESVI (23.3 ± 1.9 versus 23.5 ± 1.9 mL/m2, P = 0.733) and SVI (47.9 ± 2.9 versus 47.7 ± 3.7 mL/m2, P = 0.698) except for CI and MI. Females had significantly (P < 0.05) greater CI (3.5 ± 0.4 versus 3.3 ± 0.4) but smaller MI (46.9 ± 5.3 versus 53.6 ± 7.6) than males. EDV, EDVI, ESV, ESVI, SV, and SVI significantly (P < 0.05) decreased with age increase. BSA was positively correlated with EDV, ESV, SV, MM, and CO. No significance (P > 0.05) was detected in other parameters.
  
  
  
  The left ventricular volume and function differs in women compared with men in the middle-aged population, and these parameters have a tendency of decrease with ageing. J. Magn. Reson. Imaging 2016;44:1143-1150.
authors.affiliation: Department of Medical Imaging, Second Hospital, Hebei Medical University, Hebei, China. licaiying63@163.com.
authors.forename: Cai-Ying
authors.initials: CY
authors.lastname: Li
authors.affiliation: Department of Medical Research, Shijiazhuang First Hospital, Hebei Medical University, Hebei, China. browngao@163.com.
authors.forename: Bu-Lang
authors.initials: BL
authors.lastname: Gao
authors.affiliation: Department of Medical Imaging, Second Hospital, Hebei Medical University, Hebei, China.
authors.forename: Fu-Qian
authors.initials: FQ
authors.lastname: Guo
authors.affiliation: Department of Medical Research, Shijiazhuang First Hospital, Hebei Medical University, Hebei, China.
authors.forename: Xue-Jing
authors.initials: XJ
authors.lastname: Zhang
authors.affiliation: Department of Medical Research, Shijiazhuang First Hospital, Hebei Medical University, Hebei, China.
authors.forename: Qiong-Ying
authors.initials: QY
authors.lastname: Fan
authors.affiliation: Department of Medical Imaging, Second Hospital, Hebei Medical University, Hebei, China.
authors.forename: Bai-Lin
authors.initials: BL
authors.lastname: Wu
authors.affiliation: Department of Medical Research, Shijiazhuang First Hospital, Hebei Medical University, Hebei, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Xiang
authors.affiliation: Department of Medical Imaging, Second Hospital, Hebei Medical University, Hebei, China.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Liu
authors.affiliation: Department of Medical Imaging, Second Hospital, Hebei Medical University, Hebei, China.
authors.forename: Tong
authors.initials: T
authors.lastname: Pan
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000375:Aging / Q000473:pathology / Q000502:physiology*; D002681:China / Q000453:epidemiology; D005260:Female; D006352:Heart Ventricles / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D013318:Stroke Volume / Q000502:physiology*; D016277:Ventricular Function, Left / Q000502:physiology*
keywords: function; left ventricle; magnetic resonance imaging; middle age; volume