title: Efficacy, safety, and acceptability of thermocoagulation for treatment of cervical intraepithelial neoplasia in a hospital setting in Brazil.
abstract: OBJECTIVE
  To analyze the acceptability, safety, and effectiveness of thermocoagulation for the treatment of histologically proven cervical intraepithelial neoplasia grade 2-3 (CIN2-3) lesions.
  
  
  METHODS
  In a retrospective study, data were obtained for women treated for CIN2-3 lesions by thermocoagulation at the Hospital de Clínicas de Porto Alegre, Brazil, between March 6, 2012, and October 29, 2013, and followed up after 1 year. The proportions of women with no evidence of disease, adverse effects, or complications were determined.
  
  
  RESULTS
  Among 52 women included, 44 (85%) had no evidence of disease 1year after thermocoagulation. The rate of no disease at follow-up was similar for women treated for CIN2 (17/20 [85%]) and CIN3 (27/32 [84%]). No serious adverse effects or complications requiring hospitalization were observed during the follow-up period.
  
  
  CONCLUSIONS
  Thermocoagulation is useful in the management of ectocervical CIN and should be integrated into public health services for management of cervical cancer.
authors.affiliation: Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Paulo S V
authors.initials: PS
authors.lastname: Naud
authors.affiliation: Screening Group, Early Detection and Prevention Section, International Agency for Research on Cancer, Lyon, France.
authors.forename: Richard
authors.initials: R
authors.lastname: Muwonge
authors.affiliation: Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil; Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Eduardo P
authors.initials: EP
authors.lastname: Passos
authors.affiliation: Federal University of Rio Grande do Sul, Porto Alegre, Brazil.
authors.forename: Valentino
authors.initials: V
authors.lastname: Magno
authors.affiliation: Hospital de Clínicas de Porto Alegre, Porto Alegre, Brazil.
authors.forename: Jean
authors.initials: J
authors.lastname: Matos
authors.affiliation: Screening Group, Early Detection and Prevention Section, International Agency for Research on Cancer, Lyon, France. Electronic address: sankarr@iarc.fr.
authors.forename: Rengaswamy
authors.initials: R
authors.lastname: Sankaranarayanan
mesh_terms: D000328:Adult; D001938:Brazil; D004564:Electrocoagulation; D005260:Female; D006801:Humans; D060787:Neoplasm Grading; D012189:Retrospective Studies; D016896:Treatment Outcome; D002583:Uterine Cervical Neoplasms / Q000473:pathology* / Q000601:surgery*; D002578:Uterine Cervical Dysplasia / Q000473:pathology* / Q000601:surgery*
keywords: Cervical intraepithelial neoplasia; Thermocoagulation