title: Saccadic Impairment Associated With Remote History of Mild Traumatic Brain Injury.
abstract: Evidence suggests that mild traumatic brain injury (TBI) is associated with long-term changes in brain function, but conventional neurocognitive tools are often insensitive to deficits after 90 days. Eye movements have been proposed as a means to identify more chronic forms of impairment. In this study, saccadic, manual, and conventional neuropsychological measures were compared between participants with remote mild TBI and well-matched control participants. Saccadic impairment was more frequent within the mild TBI group, and a history of multiple injuries or high symptom burden appeared to compound this risk. However, other neurocognitive measures did not differ by group, number of injuries, or symptom severity. These results suggest that saccadic impairment may reflect chronic effects of mild TBI that conventional measures are unable to detect.
authors.affiliation: From the Dept. of Medical and Clinical Psychology, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD.
authors.forename: Mark L
authors.initials: ML
authors.lastname: Ettenhofer
authors.affiliation: From the Dept. of Medical and Clinical Psychology, F. Edward Hebert School of Medicine, Uniformed Services University of the Health Sciences, Bethesda, MD.
authors.forename: David M
authors.initials: DM
authors.lastname: Barry
mesh_terms: D000328:Adult; D001288:Attention; D001924:Brain Concussion / Q000150:complications*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology; D003936:Diagnosis, Computer-Assisted; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015835:Ocular Motility Disorders / Q000209:etiology*; D011569:Psychiatric Status Rating Scales; D012044:Regression Analysis; D012438:Saccades / Q000502:physiology*; D012720:Severity of Illness Index; D055815:Young Adult