title: Relative Stereochemistry and Absolute Configuration of Farinosin, a Eudesmanolide From Encelia farinosa.
abstract: The naturally occurring eudesmanolide farinosin () is now fully characterized for the first time despite its original isolation almost half a century ago. The early assumed relative stereochemistry and absolute configuration were confirmed by vibrational circular dichroism together with evaluation of the Hooft X-ray parameters. The molecular conformation is very similar in the gas stage and in the solid state. Chirality 28:415-419, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Mexico City, Mexico.
authors.forename: Alfredo R
authors.initials: AR
authors.lastname: Ortega
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Mexico City, Mexico.
authors.forename: Mariano
authors.initials: M
authors.lastname: Sánchez-Castellanos
authors.affiliation: Escuela Nacional de Medicina y Homeopatía, Instituto Politécnico Nacional, Mexico City, Mexico.
authors.forename: Nury
authors.initials: N
authors.lastname: Pérez-Hernández
authors.affiliation: Departamento de Ciencias Químico Biológicas, Universidad de Sonora, Hermosillo, Sonora, Mexico.
authors.forename: Ramón E
authors.initials: RE
authors.lastname: Robles-Zepeda
authors.affiliation: Departamento de Química, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, Mexico City, Mexico.
authors.forename: Pedro
authors.initials: P
authors.lastname: Joseph-Nathan
authors.affiliation: Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Mexico City, Mexico.
authors.forename: Leovigildo
authors.initials: L
authors.lastname: Quijano
mesh_terms: D019659:Asteraceae / Q000737:chemistry*; D002942:Circular Dichroism; D018360:Crystallography, X-Ray; D015394:Molecular Structure; D012717:Sesquiterpenes / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D012717:Sesquiterpenes; C476916:eudesmanolide
keywords: Hooft parameter; absolute configuration; relative stereochemistry; single crystal X-ray diffraction; vibrational circular dichroism