title: Dual-channel optical sensing platform for detection of diminazene aceturate based on thioglycolic acid-wrapped cadmium telluride/cadmium sulfide quantum dots.
abstract: A dual-channel optical sensing platform which combines the advantages of dual-wavelength overlapping resonance Rayleigh scattering (DWO-RRS) and fluorescence has been designed for the detection of diminazene aceturate (DA). It is based on the use of thioglycolic acid-wrapped CdTe/CdS quantum dots (Q-dots). In the absence of DA, the thioglycolic acid-wrapped CdTe/CdS Q-dots exhibit the high fluorescence spectrum and low RRS spectrum, so are selected to develop an easy-to-get system. In the presence of DA, the thioglycolic acid-wrapped CdTe/CdS Q-dots and DA form a complex through electrostatic interaction, which result in the RRS intensity getting enhanced significantly with new RRS peaks appearing at 317 and 397 nm; the fluorescence is powerfully quenched. Under optimum conditions, the scattering intensities of the two peaks are proportional to the concentration of DA in the range of 0.0061-3.0 μg mL(-1). The detection limits for the two single peaks are 4.1 ng mL(-1) and 3.3 ng mL(-1), while that of the DWO-RRS method is 1.8 ng mL(-1), indicating that the DWO-RRS method has high sensitivity. Besides, the fluorescence also exhibits good linear range from 0.0354 to 10.0 μg mL(-1) with a detection limit of 10.6 ng mL(-1). In addition, the system has been applied to the detection of DA in milk samples with satisfactory results.
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Chenxia
authors.initials: C
authors.lastname: Hao
authors.affiliation: College of Chemistry & Chemical Engineering, Chongqing University, Chongqing 400044, PR China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhou
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Shaopu
authors.initials: S
authors.lastname: Liu
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Linlin
authors.initials: L
authors.lastname: Wang
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Bowen
authors.initials: B
authors.lastname: Huang
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China.
authors.forename: Nianxi
authors.initials: N
authors.lastname: Kuang
authors.affiliation: Key Laboratory on Luminescence and Real-Time Analysis, Ministry of Education, School of Chemistry and Chemical Engineering, Southwest University, Chongqing 400715, PR China. Electronic address: heyq@swu.edu.cn.
authors.forename: Youqiu
authors.initials: Y
authors.lastname: He
mesh_terms: D000818:Animals; D000981:Antiprotozoal Agents / Q000032:analysis*; D019187:Cadmium Compounds / Q000737:chemistry*; D004133:Diminazene / Q000031:analogs & derivatives* / Q000032:analysis; D005506:Food Contamination / Q000032:analysis; D057230:Limit of Detection; D008892:Milk / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure; D013050:Spectrometry, Fluorescence / Q000379:methods; D013056:Spectrophotometry, Ultraviolet; D013440:Sulfides / Q000737:chemistry*; D013691:Tellurium / Q000737:chemistry*; D013864:Thioglycolates / Q000737:chemistry*
chemical_list: D000981:Antiprotozoal Agents; D019187:Cadmium Compounds; D013440:Sulfides; D013864:Thioglycolates; C034939:cadmium sulfide; C017487:2-mercaptoacetate; C003915:diminazene aceturate; D013691:Tellurium; C028337:cadmium telluride; D004133:Diminazene
keywords: Diminazene aceturate; Dual-wavelength overlapping resonance Rayleigh scattering; Fluorescence; Quantum dots