title: Effects of chlorhexidine (gel) application on bacterial levels and orthodontic brackets during orthodontic treatment.
abstract: The objectives of this study were to evaluate the effects of applying 0.50% chlorhexidine (CHX) gel using the dental drug delivery system (3DS) on salivary Streptococcus mutans (S. mutans) and on the surface topography of metal and ceramic orthodontic brackets. The study involved 20 orthodontic patients with high levels of salivary S. mutans. The patients were treated with professional mechanical tooth cleaning followed by application of 0.50% CHX using individual trays (3DS). Salivary S. mutans levels were repeatedly measured 1, 2, 4, and 8 weeks post-treatment. In vitro study utilized forty ceramic and metallic brackets that were immersed in 0.50% CHX gel for 10 min, whereas another untreated forty brackets served as controls. The frictional resistances of stainless steel wires to the brackets before and after CHX treatment were recorded using a universal testing machine. Scanning electron microscopy was used to compare changes in the surface topography of brackets. Statistical analyses were used to determine the effect of CHX on bacterial count and to evaluate the effect of CHX on frictional resistance. According to the results of this study, S. mutans levels were reduced significantly (P < 0.05). There were no significant changes in the frictional resistance and surface topography of brackets before or after application of CHX. (J Oral Sci 58, 35-42, 2016).
authors.affiliation: Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University.
authors.forename: Samar M
authors.initials: SM
authors.lastname: Al-Bazi
authors.forename: Mona A
authors.initials: MA
authors.lastname: Abbassy
authors.forename: Ahmed S
authors.initials: AS
authors.lastname: Bakry
authors.forename: Leena A
authors.initials: LA
authors.lastname: Merdad
authors.forename: Ali H
authors.initials: AH
authors.lastname: Hassan
mesh_terms: D000891:Anti-Infective Agents, Local / Q000008:administration & dosage*; D001419:Bacteria / Q000302:isolation & purification*; D002710:Chlorhexidine / Q000008:administration & dosage*; D015169:Colony Count, Microbial; D008855:Microscopy, Electron, Scanning; D016910:Orthodontic Brackets
chemical_list: D000891:Anti-Infective Agents, Local; D002710:Chlorhexidine