title: Molecularly Responsive Binding through Co-occupation of Binding Space: A Lock-Key Story.
abstract: When two guest molecules co-occupy a binding pocket of a water-soluble host, the first guest could be used as a signal molecule to turn on the binding of the second. This type of molecularly responsive binding strongly depends on the size of the two guests and the location of the signal molecule.
authors.affiliation: Department of Chemistry, Iowa State University , Ames, Iowa 50011-3111, United States.
authors.forename: Joseph K
authors.initials: JK
authors.lastname: Awino
authors.affiliation: Department of Chemistry, Iowa State University , Ames, Iowa 50011-3111, United States.
authors.forename: Lan
authors.initials: L
authors.lastname: Hu
authors.affiliation: Department of Chemistry, Iowa State University , Ames, Iowa 50011-3111, United States.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D001665:Binding Sites; D047028:Macrocyclic Compounds / Q000737:chemistry*; D015394:Molecular Structure; D010084:Oxidation-Reduction; D012995:Solubility; D014230:Triazoles / Q000737:chemistry*; D014753:Vinyl Compounds / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D047028:Macrocyclic Compounds; D014230:Triazoles; D014753:Vinyl Compounds; D014867:Water