title: Contribution of inorganic and organic components to sorption of neutral and ionizable pharmaceuticals by sediment/soil.
abstract: Our previous study showed that the sorption coefficient of certain polar pharmaceuticals to river sediment, especially particular amines, was unexpectedly high. Thus, we conducted sorption experiments of selected polar pharmaceuticals and pyrene derivatives, including amines, carboxylic acids, and neutral compounds, to model clay minerals, i.e., montmorillonite and kaolin, in addition to silica sands and humic substances. The contribution of each component was roughly estimated by simple fractionation of the individual sorption coefficients. Relatively high sorption coefficients (Kdvalues) were found, especially for amines on clay minerals, which suggest that electrochemical affinity may play an important role. The estimated contribution percentage suggests a relatively large contribution from inorganic constituents, such as clay minerals, for silt loam soil; in contrast, organic components predominantly contribute for sandy river sediments. These findings could be the key to understanding not only the fate and transport but also bioavailability and environmental risks of pharmaceuticals, which are mostly polar and/or ionizable.
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan. hiroshi.yamamoto@tokushima-u.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Yamamoto
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.|Research Center for Environmental Quality Management, Kyoto University, 1-1 Yumihama, Otsu, Shiga, Japan.
authors.forename: Kohei
authors.initials: K
authors.lastname: Takemoto
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.|National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki, 305-8506, Japan.
authors.forename: Ikumi
authors.initials: I
authors.lastname: Tamura
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.
authors.forename: Norihiro
authors.initials: N
authors.lastname: Shin-Oka
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakano
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.
authors.forename: Masayo
authors.initials: M
authors.lastname: Nishida
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Honda
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.
authors.forename: Shigemi
authors.initials: S
authors.lastname: Moriguchi
authors.affiliation: Faculty of Integrated Arts and Sciences, Tokushima University, 1-1 Minamijosanjima-cho, Tokushima, 770-8502, Japan.
authors.forename: Yudai
authors.initials: Y
authors.lastname: Nakamura
mesh_terms: D000327:Adsorption; D001546:Bentonite / Q000737:chemistry*; D001682:Biological Availability; D000077215:Clay; D019015:Geologic Sediments; D006812:Humic Substances / Q000032:analysis*; D008903:Minerals / Q000737:chemistry*; D045483:Rivers; D012987:Soil / Q000737:chemistry*; D012989:Soil Pollutants / Q000032:analysis*
chemical_list: D006812:Humic Substances; D008903:Minerals; D012987:Soil; D012989:Soil Pollutants; D001546:Bentonite; D000077215:Clay
keywords: Cation-exchange capacity; Clay minerals; Electrochemical affinity; Pharmaceuticals; Sediment; Sorption