title: Crystal structure of ethyl 2-[2-(4-methyl-benzo-yl)-5-p-tolyl-1H-imidazol-1-yl]acetate.
abstract: In the title compound, C22H22N2O3, the plane of the five-membered ring is oriented at dihedral angles of 45.4 (1) and 52.5 (1)° to the phenyl rings. Furthermore, this ring makes an angle of 85.2 (2)° with the plane of the ethyl acetate substituent. The mol-ecular structure is affected by an intra-molecular C-H⋯O hydrogen bond between an H atom from the p-tolyl group and the carbonyl O atom of the acetate. The methyl group of the ethyl acetate residue is disordered over two sites with equal occupancies. The crystal structure features inter-molecular C-H⋯O and C-H⋯N inter-actions. One of the C-H⋯O hydrogen bonds forms a C(5) chain motif extending along the a axis. In addition, C-H⋯N contacts form inversion dimers with R 2 (2)(12) ring motifs, linking the imidazole ring system to the benzene ring of the p-tolyl substituent.
authors.affiliation: Department of Physics, University College of Engineering Nagercoil, Anna University, Nagercoil 629 004, India.
authors.forename: E Arockia Jeya Yasmi
authors.initials: EA
authors.lastname: Prabha
authors.affiliation: Department of Physics, University College of Engineering Nagercoil, Anna University, Nagercoil 629 004, India.
authors.forename: S Suresh
authors.initials: SS
authors.lastname: Kumar
authors.affiliation: Medicinal Chemistry Division, Indian Institute of Integrative Medicine (IIIM) and Academy of Scientific and Innovative Research (AcSIR-IIIM), Jammu 180 001, India.
authors.forename: Anil K
authors.initials: AK
authors.lastname: Padala
authors.affiliation: Medicinal Chemistry Division, Indian Institute of Integrative Medicine (IIIM) and Academy of Scientific and Innovative Research (AcSIR-IIIM), Jammu 180 001, India.
authors.forename: Qazi Naveed
authors.initials: QN
authors.lastname: Ahmed
authors.affiliation: Department of Physics, University College of Engineering Nagercoil, Anna University, Nagercoil 629 004, India.
authors.forename: S
authors.initials: S
authors.lastname: Athimoolam
keywords: 2-(4-meth­oxy­phen­yl)-2-oxoacetaldehyde; crystal structure; glycine methyl ester hydro­chloride; imidazole derivative; new synthesis