title: Pelianthinarubins A and B, Red Pyrroloquinoline Alkaloids from the Fruiting Bodies of the Mushroom Mycena pelianthina.
abstract: Pelianthinarubin A (1) and pelianthinarubin B (2), two previously unknown pyrroloquinoline alkaloids, have been isolated from fruiting bodies of Mycena pelianthina. The structures of these alkaloids have been deduced from their HR-(+)-ESIMS and 2D NMR data. The absolute configurations of the pelianthinarubins A (1) and B (2) were assigned by analysis of the NOE correlations and coupling constants and by comparison of the CD spectra of 1 and 2 and of hercynine obtained by degradation of 1 with suitable compounds of known absolute configuration. The pelianthinarubins A (1) and B (2), which contain an S-hercynine moiety, differ considerably from the known pyrroloquinoline alkaloids from marine organisms and other Mycena species, such as the mycenarubins, the haematopodins, and the sanguinones.
authors.affiliation: Institut für Organische und Analytische Chemie, Universität Bremen , Leobener Straße NW2C, D-28359 Bremen, Germany.
authors.forename: Anna
authors.initials: A
authors.lastname: Pulte
authors.affiliation: Institut für Organische und Analytische Chemie, Universität Bremen , Leobener Straße NW2C, D-28359 Bremen, Germany.
authors.forename: Silke
authors.initials: S
authors.lastname: Wagner
authors.affiliation: Institut für Organische und Analytische Chemie, Universität Bremen , Leobener Straße NW2C, D-28359 Bremen, Germany.
authors.forename: Herbert
authors.initials: H
authors.lastname: Kogler
authors.affiliation: Institut für Organische und Analytische Chemie, Universität Bremen , Leobener Straße NW2C, D-28359 Bremen, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Spiteller
mesh_terms: D000363:Agaricales / Q000737:chemistry*; D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification*; D001622:Betaine / Q000031:analogs & derivatives / Q000737:chemistry; D048690:Fruiting Bodies, Fungal / Q000737:chemistry*; D005858:Germany; D006639:Histidine / Q000031:analogs & derivatives / Q000737:chemistry; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D011758:Pyrroles / Q000737:chemistry / Q000302:isolation & purification*; D011804:Quinolines / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D000470:Alkaloids; D011758:Pyrroles; D011804:Quinolines; C000610477:pelianthinarubin A; C000610478:pelianthinarubin B; C410406:pyrroloquinoline; D001622:Betaine; D006639:Histidine; C007928:hercynine