title: [Infection status and virulent genes of Aeromonas in diarrhea patients in Pudong New Area, Shanghai].
abstract: OBJECTIVE
  To investigate the infection status and virulent genes of Aeromonas in patients with acute diarrhea in Pudong New Area, Shanghai.
  
  
  METHODS
  In 2012, stool samples were collected from diarrhea patients in 12 sentinel hospitals in Pudong for the detections of 13 pathogens causing diarrhea, and the detections of 5 diarrhea related virulent genes were conducted for Aeromonas isolates.
  
  
  RESULTS
  A total of 101 patients were infected with Aeromonas in 2533 patients (4.0%). A total of 101 Aeromonas strains were isolated, including 17 Aeromonas hydrophila strains (18.8%), 44 Aeromonas veronii biovar sobria strains (52.5%) and 12 Aeromonas caviae strains (29.7%). And 44 coinfections with other pathogens were detected. Aeromonas infection mainly occurred in summer and in people aged ≥20 years. Among the patients infected with Aeromonas, 71 (70.3%) had watery diarrhea, 20 (19.8%) had vomiting and 11 (10.9%) had fever. Virulent genes detection showed that 95.0% of the Aeromonas. strains carried virulent genes, and the detection rates of hlyA, aerA, act, alt, and ast genes were 5.9%, 6.9%, 67.3%, 42.6% and 13.9%, respectively.
  
  
  CONCLUSIONS
  High incidence of Aeromonas infection was found in the patients with acute diarrhea in Pudong, and a high proportion of coinfections with other pathogens was detected too. Most Aeromonas strains carried virulent genes, and the distribution varied.
authors.affiliation: Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Wenqing
authors.initials: W
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Communicable Disease Control and Prevention, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
authors.forename: Duochun
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Linying
authors.initials: L
authors.lastname: Zhu
authors.affiliation: Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Yifei
authors.initials: Y
authors.lastname: Fu
authors.affiliation: Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Lipeng
authors.initials: L
authors.lastname: Hao
authors.affiliation: Department of Microbiology of Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China.
authors.forename: Xuebin
authors.initials: X
authors.lastname: Xu
authors.affiliation: Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Jinghua
authors.initials: J
authors.lastname: Su
authors.affiliation: Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Huiqin
authors.initials: H
authors.lastname: Fu
authors.affiliation: Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Chuchu
authors.initials: C
authors.lastname: Ye
authors.affiliation: Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China.
authors.forename: Qiao
authors.initials: Q
authors.lastname: Sun
authors.affiliation: Key Laboratory of Public Health Safety of the Ministry of Education, Department of Public Health Microbiology, Fudan University School of Public Health, Shanghai 200032, China.
authors.forename: Yingjie
authors.initials: Y
authors.lastname: Zheng
mesh_terms: D000333:Aeromonas / Q000235:genetics*; D016980:Aeromonas hydrophila / Q000235:genetics; D002681:China / Q000453:epidemiology; D003967:Diarrhea / Q000382:microbiology*; D016905:Gram-Negative Bacterial Infections / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D012621:Seasons; D014774:Virulence / Q000235:genetics*; D055815:Young Adult