title: Neutrophil Gelatinase Associated Lipocalin (NGAL) as a Biomarker. Does It Apply in Abdominal Aortic Aneurysms? A Review of Literature.
abstract: Neutrophil gelatinase associated lipocalin (NGAL) as a protein derived from neutrophils has recently been the field of investigation in a wide range of diseases (renal disease, coronary artery disease, etc). The MEDLINE/PubMed database was searched for publications with the medical subject heading "NGAL" and keywords "Abdominal aortic aneurysm (AAA)," "biomarker," and "growth". We restricted our search to date. In this review, we included 38 articles and abstracts that were accessible and available in English. An effort to further explain the role of NGAL within AAA has been made. NGAL seems to be a hopeful marker for the pathogenesis and the progression of abdominal aortic aneurysms (AAAs), which has significant morbidity and mortality rates.
authors.affiliation: 2nd Department of Surgery, Vascular Surgery Unit, School of Medicine, Laikon General Hospital, Athens, Greece.
authors.forename: Georgios
authors.initials: G
authors.lastname: Karaolanis
authors.affiliation: 1st Department of Surgery, Vascular Surgery Unit, School of Medicine, Laikon General Hospital, Athens, Greece.
authors.forename: Demetrios
authors.initials: D
authors.lastname: Moris
authors.affiliation: 2nd Department of Surgery, Vascular Surgery Unit, School of Medicine, Laikon General Hospital, Athens, Greece.
authors.forename: Viktoria-Varvara
authors.initials: VV
authors.lastname: Palla
authors.affiliation: 2nd Department of Surgery, Vascular Surgery Unit, School of Medicine, Laikon General Hospital, Athens, Greece.
authors.forename: Euridiki
authors.initials: E
authors.lastname: Karanikola
authors.affiliation: 1st Department of Surgery, Vascular Surgery Unit, School of Medicine, Laikon General Hospital, Athens, Greece.
authors.forename: Chris
authors.initials: C
authors.lastname: Bakoyiannis
authors.affiliation: 1st Department of Surgery, Vascular Surgery Unit, School of Medicine, Laikon General Hospital, Athens, Greece.
authors.forename: Sotirios
authors.initials: S
authors.lastname: Georgopoulos
keywords: Abdominal aortic aneurysm (AAA); Biomarkers; Growth; Neutrophil gelatinase associated lipocalin (NGAL)