title: Comparison of Blood Loss After Total Hip Arthroplasty Between Ankylosing Spondylitis and Osteoarthritis.
abstract: This study was conducted to compare the blood loss during primary total hip arthroplasty (THA) between ankylosing spondylitis (AS) and hip osteoarthritis (OA).
  
  
  
  We reviewed 120 THAs in 68 patients comprising 3 groups: AS with total bony ankylosis of the hips (ASB), AS with stiff hips (ASS), and OA. Demographics, perioperative laboratory values, intraoperative data, blood loss, transfusion rate, transfusion reactions, surgical complications, hospitalization cost, and length of stay (LOS) were collected and analyzed among ASB, ASS, and OA groups.
  
  
  
  The patients of the ASB and ASS groups were much younger and thinner than those of the OA group. There were no significant differences in the preoperative values of activated partial thromboplastin time, prothrombin time, and international normalized ratio among the 3 groups (all P > .05). The intraoperative blood loss, volume of drainage, hidden blood loss, transfusion rate, transfusion reactions, and hospitalization cost in the ASB group were significantly higher than in the other 2 groups, although not significantly different between the ASS and OA groups (P > .05).
  
  
  
  Both AS and OA can cause hyperosteogeny to the hips, but ASB patients have more serious symptoms in their affected hips. This may cause more blood loss in THA surgery because of bone surface bleeding. The reason that ASB patients suffered more blood loss may be related to the high difficulty and long duration of the operation.
authors.affiliation: Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, China.
authors.forename: Jia
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Orthopedics, No. 401 Hospital, Jinan Military Region of PLA, Qingdao, Shandong, China.
authors.forename: Jinzhu
authors.initials: J
authors.lastname: Zhao
authors.affiliation: Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, China.
authors.forename: Chongru
authors.initials: C
authors.lastname: He
authors.affiliation: Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, China.
authors.forename: Wenwen
authors.initials: W
authors.lastname: Tong
authors.affiliation: Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, China.
authors.forename: Yuming
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, China.
authors.forename: Weidong
authors.initials: W
authors.lastname: Xu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D016063:Blood Loss, Surgical; D001803:Blood Transfusion; D005260:Female; D006621:Hip Joint / Q000601:surgery; D006801:Humans; D008297:Male; D008875:Middle Aged; D015207:Osteoarthritis, Hip / Q000601:surgery*; D012189:Retrospective Studies; D012307:Risk Factors; D013167:Spondylitis, Ankylosing / Q000601:surgery*; D055815:Young Adult
keywords: ankylosing spondylitis; blood loss; osteoarthritis; osteophyma; total hip arthroplasty