title: Unprecedented iron-catalyzed selective hydrogenation of activated amides to amines and alcohols.
abstract: The first example of hydrogenation of amides homogeneously catalyzed by an earth-abundant metal complex is reported. The reaction is catalyzed by iron PNP pincer complexes. A wide range of secondary and tertiary N-substituted 2,2,2-trifluoroacetamides were hydrogenated to form amines and trifluoroethanol.
authors.affiliation: Department of Organic Chemistry, Weizmann Institute of Science, 76100 Rehovot, Israel. david.milstein@weizmann.ac.il.
authors.forename: Jai Anand
authors.initials: JA
authors.lastname: Garg
authors.forename: Subrata
authors.initials: S
authors.lastname: Chakraborty
authors.forename: Yehoshoa
authors.initials: Y
authors.lastname: Ben-David
authors.forename: David
authors.initials: D
authors.lastname: Milstein