title: Spectroscopic Terahertz Imaging at Room Temperature Employing Microbolometer Terahertz Sensors and Its Application to the Study of Carcinoma Tissues.
abstract: A terahertz (THz) imaging system based on narrow band microbolometer sensors (NBMS) and a novel diffractive lens was developed for spectroscopic microscopy applications. The frequency response characteristics of the THz antenna-coupled NBMS were determined employing Fourier transform spectroscopy. The NBMS was found to be a very sensitive frequency selective sensor which was used to develop a compact all-electronic system for multispectral THz measurements. This system was successfully applied for principal components analysis of optically opaque packed samples. A thin diffractive lens with a numerical aperture of 0.62 was proposed for the reduction of system dimensions. The THz imaging system enhanced with novel optics was used to image for the first time non-neoplastic and neoplastic human colon tissues with close to wavelength-limited spatial resolution at 584 GHz frequency. The results demonstrated the new potential of compact RT THz imaging systems in the fields of spectroscopic analysis of materials and medical diagnostics.
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. irmantak@ktl.mii.lt.
authors.forename: Irmantas
authors.initials: I
authors.lastname: Kašalynas
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. rimvydas.venckevicius@ftmc.lt.
authors.forename: Rimvydas
authors.initials: R
authors.lastname: Venckevičius
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. linas.minkevicius@ftmc.lt.
authors.forename: Linas
authors.initials: L
authors.lastname: Minkevičius
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, Ljubljana 1000, Slovenia. aleksander.sesek@fe.uni-lj.si.
authors.forename: Aleksander
authors.initials: A
authors.lastname: Sešek
authors.affiliation: Instituto de Investigacao e Inovacao em Saudeand, Instituto de Engenharia Biomedica, University of Porto, Rua do Campo Alegre, 823, Porto 4150-180, Portugal. fwahaia@fc.up.pt.
authors.forename: Faustino
authors.initials: F
authors.lastname: Wahaia
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. vincas.tamosiunas@ftmc.lt.
authors.forename: Vincas
authors.initials: V
authors.lastname: Tamošiūnas
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. bogdan.voisiat@ftmc.lt.
authors.forename: Bogdan
authors.initials: B
authors.lastname: Voisiat
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. dalius@pfi.lt.
authors.forename: Dalius
authors.initials: D
authors.lastname: Seliuta
authors.affiliation: Department of Optoelectronics, Center for Physical Sciences and Technology, Savanoriu Ave. 231, Vilnius 02300, Lithuania. gintaras.valusis@ftmc.lt.
authors.forename: Gintaras
authors.initials: G
authors.lastname: Valušis
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, Ljubljana 1000, Slovenia. andrej.svigelj@fe.uni-lj.si.
authors.forename: Andrej
authors.initials: A
authors.lastname: Švigelj
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Trzaska 25, Ljubljana 1000, Slovenia. janez.trontelj1@guest.arnes.si.
authors.forename: Janez
authors.initials: J
authors.lastname: Trontelj
mesh_terms: D002277:Carcinoma / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D003110:Colonic Neoplasms / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000503:physiopathology; D006801:Humans; D025341:Principal Component Analysis; D017550:Spectroscopy, Fourier Transform Infrared; D055069:Terahertz Imaging / Q000379:methods*; D055068:Terahertz Spectroscopy / Q000379:methods*
keywords: THz imaging systems; compact THz sensors and components; medical THz imaging; multispectral THz imaging