title: Simultaneous Determination of 10 Photoinitiators in Milk by Solid-Phase Microextraction Coupled with Gas Chromatography/Mass Spectrometry.
abstract: Photoinitiators (PIs) are widely used in food packaging materials, can migrate easily from packaging materials to food, and cause food contamination. It is essential to establish a method of determining PIs residues in food. A new method for simultaneously determining 10 kinds of PIs in milk has been established by using solid-phase microextraction (SPME) combined with a simple method of protein precipitation as the pretreatment approach and gas chromatography/mass spectrometry as the detecting technique. The limits of detection for 10 PIs in different milks were between 0.05 and 1.4 μg/L (skimmed milk), between 0.07 and 2.2 μg/L (semi-skimmed milk), between 0.11 and 4.4 μg/L (whole milk), respectively. The recoveries were from 71.5% to 133.5%, and the relative standard deviations were less than 15%. Twelve kinds of packed milk with different brands and fat contents were determined using this method.
authors.affiliation: College of Chemistry & Environmental Science, Hebei Univ, Baoding, 071000, China.|Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, 071000, China.
authors.forename: Pengyan
authors.initials: P
authors.lastname: Liu
authors.affiliation: College of Chemistry & Environmental Science, Hebei Univ, Baoding, 071000, China.|Key Laboratory of Analytical Science and Technology of Hebei Province, Baoding, 071000, China.
authors.forename: Chunxia
authors.initials: C
authors.lastname: Zhao
authors.affiliation: College of Chemistry & Environmental Science, Hebei Univ, Baoding, 071000, China.
authors.forename: Yajing
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: College of Chemistry & Environmental Science, Hebei Univ, Baoding, 071000, China.
authors.forename: Yanjie
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000098:Acetophenones / Q000032:analysis; D000818:Animals; D001577:Benzophenones / Q000032:analysis; D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D015386:Hazardous Substances / Q000032:analysis*; D006801:Humans; D008892:Milk / Q000737:chemistry*; D052617:Solid Phase Microextraction / Q000379:methods; D013892:Thioxanthenes / Q000032:analysis; D062366:para-Aminobenzoates / Q000032:analysis
chemical_list: D000098:Acetophenones; D001577:Benzophenones; D015386:Hazardous Substances; D013892:Thioxanthenes; C523330:ethyl 4-N,N-dimethylaminobenzoate; C518329:isopropyl-9H-thioxanthen-9-one; D062366:para-Aminobenzoates
keywords: determination; gas chromatography/mass spectrometry; milk; photoinitiators; solid-phase microextraction