title: [Atypical case of acute retinal necrosis secondary to the primary herpes simplex infection].
abstract: Acute retinal necrosis is a rare manifestation of viral chorioretinitis, accompanied by occlusive vasculitis, which is associated with poor visual prognosis. The main causal factors include varicella-zoster virus in older patients and herpes simplex in younger ones. The disease typically manifests as a reactivation of latent infections. We present a case of a 57-year-old female with atypical clinical manifestation of acute retinal necrosis secondary to the primary viral infection with herpes simplex. The serology panel of vitreous tap and blood sample confirmed viral aetiology (H. simplex). The initial clinical signs included optic disc edema with retinitis presenting as self-limiting, slowly progressing, peripheral lesions, later followed by uveitis. The antiviral therapy resolved the symptoms of uveitis and enabled healing of retinal lesions, however the natural course of disease was later complicated with retinal detachment. It was successfully treated with vitreoretinal surgery. Despite aggressive treatment, the final visual outcome was unfavourable, due to optic nerve atrophy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Terelak-Borys
authors.forename: Aldona
authors.initials: A
authors.lastname: Krzyźewska-Niedzialek
authors.forename: Agnieszka
authors.initials: A
authors.lastname: Jamrozy-Witkowska
authors.forename: Piotr K
authors.initials: PK
authors.lastname: Borkowski
authors.forename: Magdalena
authors.initials: M
authors.lastname: Ulińska
authors.forename: Iwona
authors.initials: I
authors.lastname: Grabska-Liberek
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use; D018450:Disease Progression; D015828:Eye Infections, Viral / Q000150:complications* / Q000188:drug therapy; D005260:Female; D006561:Herpes Simplex / Q000150:complications* / Q000188:drug therapy; D006801:Humans; D008875:Middle Aged; D012163:Retinal Detachment / Q000209:etiology* / Q000601:surgery; D015882:Retinal Necrosis Syndrome, Acute / Q000209:etiology* / Q000473:pathology; D014605:Uveitis / Q000188:drug therapy / Q000209:etiology; D057586:Vitreoretinal Surgery
chemical_list: D000998:Antiviral Agents