title: Chronic Traumatic Encephalopathy and Movement Disorders: Update.
abstract: Association of repetitive brain trauma with progressive neurological deterioration has been described since the 1920s. Punch drunk syndrome and dementia pugilistica (DP) were introduced first to explain symptoms in boxers, and more recently, chronic traumatic encephalopathy (CTE) has been used to describe a neurodegenerative disease in athletes and military personal with a history of multiple concussions. Although there are many similarities between DP and CTE, a number of key differences are apparent especially when comparing movement impairments. The aim of this review is to compare clinical and pathological aspects of DP and CTE with a focus on disorders of movement.
authors.affiliation: Division of Neurology, Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Canada.|UHN-Toronto Western Hospital, Concussion Clinic, 750 Dundas St, West (Med West), Room 3-313, Mailbox no. 2, Toronto, ON, M6J 3S3, Canada.
authors.forename: Apameh
authors.initials: A
authors.lastname: Tarazi
authors.affiliation: Division of Neurology, Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Canada.|Krembil Research Institute, Toronto Western Hospital, Toronto, Canada.|University of Toronto, Division of Neurosurgery and Toronto Western Hospital Senior Scientist, Toronto Western Research Institute, Toronto Western Hospital, 4W-422-399 Bathurst St., Toronto, ON, M5T 2S8, Canada.
authors.forename: Charles H
authors.initials: CH
authors.lastname: Tator
authors.affiliation: Division of Neurology, Krembil Neuroscience Centre, Toronto Western Hospital, Toronto, Canada. Carmela.tartaglia@uhn.ca.|Krembil Research Institute, Toronto Western Hospital, Toronto, Canada. Carmela.tartaglia@uhn.ca.|Tanz Center for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Tower, 60 Leonard Avenue, 6th Floor, 6KD407, Toronto, ON, M5T 2S8, Canada. Carmela.tartaglia@uhn.ca.
authors.forename: Maria Carmela
authors.initials: MC
authors.lastname: Tartaglia
mesh_terms: D000818:Animals; D001924:Brain Concussion / Q000150:complications; D020208:Brain Injury, Chronic / Q000150:complications* / Q000473:pathology; D006801:Humans; D009069:Movement Disorders / Q000209:etiology*
keywords: Chronic traumatic encephalopathy; Concussion; Dementia pugilistica; Postconcussion syndrome; Tauopathy