title: From FHB Resistance QTLs to Candidate Genes Identification in Triticum aestivum L.
abstract: Fusarium head blight (FHB) caused by Fusarium graminearum is a worldwide destructive disease affecting cereals such as wheat. FHB resistance is a quantitative trait, and information for FHB resistance QTLs in wheat is available. However, little is known about genes underlying the FHB resistance QTL regions. Using a computational approach in this study, we have mined eight FHB resistance QTLs in wheat and predicted the candidate genes falling within these QTL intervals based on the available sequences and markers. A total of 18 genomic scaffolds located at chromosomes 2AL, 2DL, 3B and 4BS were prioritized to harbor FHB-resistant candidate genes. These genes are mainly involved in plant defense response, immune regulation and cellular detoxification. We believe that our results constitute a starting point for further validation to improve FHB-resistant bread wheat varieties.
authors.affiliation: Laboratory of Plant Protection and Improvement, Center of Biotechnology of Sfax, University of Sfax, Route Sidi Mansour, Po Box 1177, 3018, Sfax, Tunisia. mouna.choura@cbs.rnrt.tn.
authors.forename: Mouna
authors.initials: M
authors.lastname: Choura
authors.affiliation: Laboratory of Plant Protection and Improvement, Center of Biotechnology of Sfax, University of Sfax, Route Sidi Mansour, Po Box 1177, 3018, Sfax, Tunisia.
authors.forename: Moez
authors.initials: M
authors.lastname: Hanin
authors.affiliation: Molecular and Cellular Diagnosis Processes, Centre of Biotechnology of Sfax, University of Sfax, Sfax, Tunisia.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Rebaï
authors.affiliation: International Center for Biosaline Agriculture (ICBA), Dubai, United Arab Emirates.
authors.forename: Khaled
authors.initials: K
authors.lastname: Masmoudi
mesh_terms: D060467:Disease Resistance / Q000235:genetics; D005670:Fusarium / Q000472:pathogenicity*; D010935:Plant Diseases / Q000235:genetics / Q000382:microbiology; D010940:Plant Proteins / Q000235:genetics*; D040641:Quantitative Trait Loci / Q000235:genetics*; D014908:Triticum / Q000235:genetics* / Q000382:microbiology*
chemical_list: D010940:Plant Proteins
keywords: Candidate gene; FHB resistance; QTL; Triticum aestivum