title: Multiple Xanthogranulomas in an Adult: Known Entity, New Association.
abstract: BACKGROUND
  Multiple xanthogranulomas (XGs) in adults are rare, although an increasing number of case reports are being published. The most frequent association is hematologic malignancies, but the majority of cases remain idiopathic, with occasional spontaneous resolution.
  
  
  OBJECTIVE
  The aims of this report are to describe a case of eruptive XG in a woman with a solid neoplasia who was receiving imatinib and to review the literature.
  
  
  RESULTS
  This 33-year-old woman had a gastrointestinal stromal tumor. After undergoing surgical removal and being on imatinib for 1 year, the patient developed multiple slightly erythematous papules with an orange hue on the axillary region, trunk, abdomen, and thighs. A biopsy confirmed the diagnosis of XG.
  
  
  CONCLUSIONS
  This is to the investigators' knowledge the first case of eruptive XG in the setting of a solid neoplasia. The possibility of drug-induced XG lesions due to imatinib cannot be excluded. This presentation could be added to the list of associations of adult XG.
authors.affiliation: Division of Dermatology, Université de Montréal, Montreal, QC, Canada sophie.vadeboncoeur@umontreal.ca.
authors.forename: Sophie
authors.initials: S
authors.lastname: Vadeboncoeur
authors.affiliation: Division of Dermatology, Université de Montréal, Montreal, QC, Canada.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Provost
mesh_terms: D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D017024:Chemotherapy, Adjuvant / Q000009:adverse effects; D003875:Drug Eruptions / Q000209:etiology* / Q000473:pathology; D005260:Female; D046152:Gastrointestinal Stromal Tumors / Q000188:drug therapy* / Q000601:surgery; D006099:Granuloma / Q000139:chemically induced* / Q000473:pathology; D015616:Histiocytosis, Non-Langerhans-Cell / Q000139:chemically induced* / Q000473:pathology; D006801:Humans; D000068877:Imatinib Mesylate / Q000009:adverse effects*; D013274:Stomach Neoplasms / Q000188:drug therapy* / Q000601:surgery; D014973:Xanthomatosis / Q000139:chemically induced* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate
keywords: GIST; adult xanthogranuloma; dermatology