title: Epidemiological Characteristics of Sapovirus and Human Astrovirus Detected among Children in Nara Prefecture, Japan, during the 2009/2010-2014/2015 Seasons.
abstract: The current study elucidated the epidemiological characteristics of sapovirus (SaV) and human astrovirus (HAstV) associated with gastroenteritis among children in regional populations of Nara Prefecture, Japan, during the 2009/2010-2014/2015 seasons. The SaV detection rate was 7.5% (71/948) according to reverse transcription-polymerase chain reaction. A high SaV detection rate of 13.5% was observed among children 4 years of age. The highest SaV detection rate was observed in June (19.2%), followed by July (11.1%). The detected SaV included 7 genotypes: GI.1, GI.2, GII.3, GII.1, GI.3, GII.2, and GV, in order of decreasing prevalence. In comparison, the HAstV detection rate was 4.2% (40/948). The HAstV detection rate among children 4 years of age was 12.2%. The HAstV detection rate was highest in July (13.9%), followed by May (10.5%) and August (6.7%). The detected HAstVs included genotypes 1, 4, 6, and 8. The most prevalent genotype was 1, followed by 4 and 8. This report provides an epidemiological overview of SaV and HAstV infection in Nara Prefecture, Japan.
authors.affiliation: Virology and Epidemiology Division, Nara Prefecture Institute of Health.
authors.forename: Masaki
authors.initials: M
authors.lastname: Yoneda
authors.forename: Mamoru
authors.initials: M
authors.lastname: Nakano
authors.forename: Daichi
authors.initials: D
authors.lastname: Sugimoto
authors.forename: Machi
authors.initials: M
authors.lastname: Inada
authors.forename: Misako
authors.initials: M
authors.lastname: Fujitani
authors.forename: Yoshiteru
authors.initials: Y
authors.lastname: Kitahori
mesh_terms: D000293:Adolescent; D019350:Astroviridae Infections / Q000453:epidemiology* / Q000821:virology; D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D002648:Child; D002675:Child, Preschool; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D008297:Male; D001257:Mamastrovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D015995:Prevalence; D020133:Reverse Transcriptase Polymerase Chain Reaction; D029341:Sapovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012621:Seasons