title: An Incidental Primary Papillary Carcinoma Arising in a Thyroglossal Duct Cyst: Report of a Rare Finding.
abstract: The thyroglossal duct cysts (TGDCs) are the most common congenital anomaly of the thyroid, usually manifested as painless midline neck mass. Malignancy is very rare and is reported in around 1% of cases as an incidental finding after histopathological evaluation of resected cyst. Papillary carcinoma is the most common carcinoma reported in TGDC. Here, we report a case of 17-year-old-female, who presented with a gradually increasing midline neck mass which moves with swallowing. On imaging a diagnosis of infected TGDC was made. The Sistrunk operation was done and a diagnosis of primary papillary carcinoma arising in a TGDC was rendered histopathologically. The contemporary appearance of papillary carcinoma thyroid was reported in about 20% cases of TGDC carcinoma, thus it is essential to differentiate primary papillary carcinoma arising in a TGDC from those of metastatic papillary carcinoma thyroid by strict diagnostic criteria.
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Mohammad Jaseem
authors.initials: MJ
authors.lastname: Hassan
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Safia
authors.initials: S
authors.lastname: Rana
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Sabina
authors.initials: S
authors.lastname: Khan
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Zeeba Shamim
authors.initials: ZS
authors.lastname: Jairajpuri
authors.affiliation: Department of Otorhinolaryngology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Seema
authors.initials: S
authors.lastname: Monga
authors.affiliation: Department of Radio-Diagnosis, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Abhinav
authors.initials: A
authors.lastname: Jain
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, Jamia Hamdard, New Delhi, India.
authors.forename: Sujata
authors.initials: S
authors.lastname: Jetley
keywords: Papillary carcinoma; Sistrunk operation; thyroglossal duct