title: Cellular Organization of Triacylglycerol Biosynthesis in Microalgae.
abstract: Eukaryotic cells are characterized by compartmentalization and specialization of metabolism within membrane-bound organelles. Nevertheless, many fundamental processes extend across multiple subcellular compartments. Here, we describe and assess the pathways and cellular organization of triacylglycerol biosynthesis in microalgae. In particular, we emphases the dynamic interplay among the endoplasmic reticulum, lipid droplets and chloroplasts in acyl remodeling and triacylglycerol accumulation under nitrogen starvation in the model alga Chlamydomonas reinhardtii.
authors.affiliation: Biology Department, Brookhaven National Laboratory, Upton, NY, 11973, USA. cxu@bnl.gov.
authors.forename: Changcheng
authors.initials: C
authors.lastname: Xu
authors.affiliation: Biology Department, Brookhaven National Laboratory, Upton, NY, 11973, USA.
authors.forename: Carl
authors.initials: C
authors.lastname: Andre
authors.affiliation: Biology Department, Brookhaven National Laboratory, Upton, NY, 11973, USA.
authors.forename: Jilian
authors.initials: J
authors.lastname: Fan
authors.affiliation: Biology Department, Brookhaven National Laboratory, Upton, NY, 11973, USA.
authors.forename: John
authors.initials: J
authors.lastname: Shanklin
mesh_terms: D000214:Acyl Coenzyme A / Q000378:metabolism; D004075:Diglycerides / Q000096:biosynthesis; D058086:Microalgae / Q000378:metabolism*; D013347:Subcellular Fractions / Q000378:metabolism; D014280:Triglycerides / Q000096:biosynthesis* / Q000378:metabolism
chemical_list: D000214:Acyl Coenzyme A; D004075:Diglycerides; D014280:Triglycerides
keywords: Acyl remodeling; Chloroplast; Endoplasmic reticulum; Oil droplet; Triacylglycerol