title: Early transcatheter valve dysfunction after transapical mitral valve-in-valve implantation.
abstract: Some patients who underwent previous mitral valve surgery experience bioprosthetic valve degeneration or recurrent mitral valve regurgitation, and the transcatheter valve-in-valve or valve-in-ring procedure is a promising therapeutic option. Early thrombotic complications have been recently reported in 0.6-0.8% of TAVI prostheses implanted in aortic position. To the best of our knowledge, this article reports on the first case of thrombotic transcatheter mitral valve dysfunction which occurred on oral anticoagulation with Coumadin in combination with antiplatelet therapy. Although it is quite a rare complication, early thrombotic dysfunction of transcatheter valve prosthesis may occur.
authors.affiliation: Department of Cardiac Surgery, Heart Center, Central Hospital Bad Berka, Bad Berka, Germany baldizon.ibarra@gmail.com.
authors.forename: Isabel
authors.initials: I
authors.lastname: Baldizon
authors.affiliation: Department of Cardiac Surgery, Heart Center, Central Hospital Bad Berka, Bad Berka, Germany.
authors.forename: Andres
authors.initials: A
authors.lastname: Espinoza
authors.affiliation: Department of Cardiac Surgery, Heart Center, Central Hospital Bad Berka, Bad Berka, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Kuntze
authors.affiliation: Department of Cardiac Surgery, Heart Center, Central Hospital Bad Berka, Bad Berka, Germany.
authors.forename: Evaldas
authors.initials: E
authors.lastname: Girdauskas
mesh_terms: D000284:Administration, Oral; D000368:Aged; D000925:Anticoagulants / Q000008:administration & dosage; D001705:Bioprosthesis; D006328:Cardiac Catheterization / Q000009:adverse effects / Q000295:instrumentation*; D017548:Echocardiography, Transesophageal; D005260:Female; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation*; D006801:Humans; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011474:Prosthesis Design; D011475:Prosthesis Failure; D013927:Thrombosis / Q000175:diagnosis / Q000209:etiology*; D013997:Time Factors; D016896:Treatment Outcome; D014859:Warfarin / Q000008:administration & dosage
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors; D014859:Warfarin
keywords: Thrombosis; Transcatheter valve therapy; Valve disease