title: Monitoring model drug microencapsulation in PLGA scaffolds using X-ray powder diffraction.
abstract: The microencapsulation of three model drugs; metronidazole, paracetamol and sulphapyridine into Poly (dl-Lactide-Co-Glycolide) (PLGA) scaffolds were probed using X-ray Powder Diffraction (XRPD). Changes in the diffraction patterns of the PLGA scaffolds after encapsulation was suggestive of a chemical interaction between the pure drugs and the scaffolds and not a physical intermixture.
authors.affiliation: Department of Mathematics and Natural Science, American University of Iraq, Kirkuk Main Road, Raparin, Sulaimani, Iraq; Drug Delivery Laboratory, School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
authors.forename: Adeyinka
authors.initials: A
authors.lastname: Aina
authors.affiliation: Drug Delivery Laboratory, School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia; School of Pharmacy, Monash University Malaysia Campus, Jalan Lagoon Selatan, 47500 Bandar Sunway, Selangor, Malaysia.
authors.forename: Manish
authors.initials: M
authors.lastname: Gupta
authors.affiliation: Drug Delivery Laboratory, School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
authors.forename: Yamina
authors.initials: Y
authors.lastname: Boukari
authors.affiliation: Drug Delivery Laboratory, School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
authors.forename: Andrew
authors.initials: A
authors.lastname: Morris
authors.affiliation: Drug Delivery Laboratory, School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
authors.forename: Nashiru
authors.initials: N
authors.lastname: Billa
authors.affiliation: Drug Delivery Laboratory, School of Pharmacy, University of Nottingham Malaysia Campus, Jalan Broga, 43500 Semenyih, Selangor Darul Ehsan, Malaysia.
authors.forename: Stephen
authors.initials: S
authors.lastname: Doughty
keywords: Encapsulation; Model drugs; PLGA; XRPD