title: Safety of prothrombin complex concentrate in healthy subjects.
authors.affiliation: Centre for Thrombosis and Haemostasis, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.|Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Stefano
authors.identifier: 0000-0002-2618-347X
authors.initials: S
authors.lastname: Barco
authors.affiliation: Oncology Unit, Istituto di Cura Città di Pavia, Gruppo San Donato, University and Research Hospital, Pavia, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Picchi
authors.affiliation: Centre for Thrombosis and Haemostasis, University Medical Centre of the Johannes Gutenberg University, Mainz, Germany.
authors.forename: Alice
authors.initials: A
authors.lastname: Trinchero
authors.affiliation: Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Saskia
authors.initials: S
authors.lastname: Middeldorp
authors.affiliation: Department of Vascular Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Michiel
authors.initials: M
authors.lastname: Coppens
mesh_terms: D001777:Blood Coagulation / Q000187:drug effects*; D001779:Blood Coagulation Factors / Q000008:administration & dosage / Q000009:adverse effects*; D064368:Healthy Volunteers; D006470:Hemorrhage / Q000188:drug therapy / Q000209:etiology; D006801:Humans
chemical_list: D001779:Blood Coagulation Factors; C025667:prothrombin complex concentrates
keywords: anticoagulants; bleeding disorders; meta-analysis; prothrombin complex concentrate; reversal; thrombosis