title: Short Communication: Rheological properties of blood serum of rats after irradiation with different gamma radiation doses in vivo.
abstract: The blood serum rheological properties open the door to find suitable radio-protectors and convenient therapy for many cases of radiation exposure. The present study aimed to investigate the rheological properties of rat blood serum at wide range of shear rates after whole body irradiation with different gamma radiation doses in vivo. Healthy male rats were divided into five groups; one control group and 4 irradiated groups. The irradiation process was carried out using Co60 source with dose rate of 0.883cG/sec. Several rheological parameters were measured using Brookfield LVDV-III Programmable rheometer. A significant increase in viscosity and shear stress was observed with 25 and 50Gy corresponding to each shear rate compared with the control; while a significant decrease observed with 75 and 100Gy. The viscosity exhibited a Non-Newtonian behaviour with the shear rate while shear stress values were linearly related with shear rate. The decrease in blood viscosity might be attributed to changes in molecular weight, pH sensitivity and protein structure. The changes in rheological properties of irradiated rats' blood serum might be attributed to destruction changes in the haematological and dimensional properties of rats' blood products.
authors.affiliation: Physics and Astronomy, King Saud University, College of Science, Riyadh, Saudi Arabia.
authors.forename: Mohamed Anwar K
authors.initials: MA
authors.lastname: Abdelhalim
authors.affiliation: Department of Physics, College of Science, Al-Imam Mohammad Ibn Saud Islamic University, Riyadh, Saudi Arabia.
authors.forename: Sherif Aa
authors.initials: SA
authors.lastname: Moussa
authors.affiliation: Physics and Astronomy, King Saud University, College of Science, Riyadh, Saudi Arabia.
authors.forename: Al-Ayed
authors.initials: AA
authors.lastname: Ms
mesh_terms: D000818:Animals; D001798:Blood Proteins / Q000737:chemistry; D001809:Blood Viscosity / Q000528:radiation effects; D005720:Gamma Rays; D018056:Hemorheology; D006863:Hydrogen-Ion Concentration; D008297:Male; D008970:Molecular Weight; D011879:Radiotherapy Dosage; D051381:Rats; D011921:Rats, Inbred WKY; D044967:Serum / Q000737:chemistry* / Q000528:radiation effects*; D033081:Shear Strength / Q000528:radiation effects
chemical_list: D001798:Blood Proteins