title: Cheilitis in acne vulgaris patients with no previous use of systemic retinoid products.
abstract: OBJECTIVE
  Isotretinoin is commonly used in the treatment of acne vulgaris. While one of the more common side-effects is cheilitis, we have observed an increased incidence of cheilitis prior to the commencement of systemic isotretinoin. The aim of this study was to assess the prevalence of cheilitis among acne vulgaris patients.
  
  
  METHODS
  A non-interventional cross-sectional study of patients with acne vulgaris. Patients with previous use of systemic retinoids were excluded. The patients were examined for signs and symptoms of cheilitis.
  
  
  RESULTS
  Of a total of 400 patients, 134 (34%) had evidence of cheilitis at initial presentation. Two-thirds (63%) were female (P < 0.001). The distribution of the cheilitis was as follows; 55% on the lower lip, 30% on both lips, and 16% on the upper lip. Over a quarter (27%) of patients with cheilitis had acne excorie, compared with only 8% of patients with no signs of cheilitis.
  
  
  CONCLUSIONS
  Our findings suggest that cheilitis is quite common among acne vulgaris patients even before treatment with isotretinoin.
authors.affiliation: Dermatology Department, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Kamran
authors.initials: K
authors.lastname: Balighi
authors.affiliation: Dermatology Department, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Daneshpazhooh
authors.affiliation: Dermatology Department, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Vahideh
authors.initials: V
authors.lastname: Lajevardi
authors.affiliation: Dermatology Department, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Shahin
authors.initials: S
authors.lastname: Talebi
authors.affiliation: Dermatology Department, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Arghavan
authors.initials: A
authors.lastname: Azizpour
mesh_terms: D000152:Acne Vulgaris / Q000453:epidemiology* / Q000523:psychology; D000293:Adolescent; D000328:Adult; D002613:Cheilitis / Q000453:epidemiology*; D015897:Comorbidity; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D055815:Young Adult
keywords: acne; acne vulgaris; cheilitis; isotretinoin; retinoid