title: Citrate-Based Biomaterials and Their Applications in Regenerative Engineering.
abstract: Advances in biomaterials science and engineering are crucial to translating regenerative engineering, an emerging field that aims to recreate complex tissues, into clinical practice. In this regard, citrate-based biomaterials have become an important tool owing to their versatile material and biological characteristics including unique antioxidant, antimicrobial, adhesive, and fluorescent properties. This review discusses fundamental design considerations, strategies to incorporate unique functionality, and examples of how citrate-based biomaterials can be an enabling technology for regenerative engineering.
authors.affiliation: Department of Biomedical Engineering, Materials Research Institute, and The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802.
authors.forename: Richard T
authors.initials: RT
authors.lastname: Tran
authors.affiliation: Department of Biomedical Engineering, Materials Research Institute, and The Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, Pennsylvania 16802.
authors.forename: Jian
authors.initials: J
authors.lastname: Yang
authors.affiliation: Biomedical Engineering Department, Northwestern University, Evanston, Illinois 60208; Department of Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611; Chemistry of Life Processes Institute, Northwestern University, Evanston, Illinois 60208; Simpson Querrey Institute for Bionanotechnology, Northwestern University, Chicago, Illinois 60611.
authors.forename: Guillermo A
authors.initials: GA
authors.lastname: Ameer
keywords: citric acid; degradation; elastomer; medical device; tissue engineering