title: Formation of α-chalcogenyl acrylamides through unprecedented chalcogen-mediated metal-free oxyfunctionalization of ynamides with DMSO as an oxidant.
abstract: A novel chalcogen-mediated oxyfunctionalization mode of ynamides for the synthesis of α-chalcogenyl acrylamides has been developed. Independent of metal catalysts, external oxidants and additives, this mild process afforded a range of structurally diverse α-chalcogenyl acrylamides, including α-selanyl acrylamides and α-tellanyl acrylamides. Interestingly, diverse ynamides tolerated in this approach gave different stereoselectivities.
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China. hegk@njtech.edu.cn zhuhj@njtech.edu.cn.
authors.forename: Hai
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China. hegk@njtech.edu.cn zhuhj@njtech.edu.cn.
authors.forename: Luning
authors.initials: L
authors.lastname: Tang
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China. hegk@njtech.edu.cn zhuhj@njtech.edu.cn.
authors.forename: Qi
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China. hegk@njtech.edu.cn zhuhj@njtech.edu.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Xi
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China. hegk@njtech.edu.cn zhuhj@njtech.edu.cn.
authors.forename: Guangke
authors.initials: G
authors.lastname: He
authors.affiliation: Department of Applied Chemistry, College of Sciences, Nanjing Tech University, Nanjing 211816, People's Republic of China. hegk@njtech.edu.cn zhuhj@njtech.edu.cn.
authors.forename: Hongjun
authors.initials: H
authors.lastname: Zhu
mesh_terms: D000178:Acrylamides / Q000138:chemical synthesis* / Q000737:chemistry; D000577:Amides / Q000737:chemistry*; D018011:Chalcogens / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D008670:Metals / Q000737:chemistry*; D016877:Oxidants / Q000737:chemistry*
chemical_list: D000178:Acrylamides; D000577:Amides; D018011:Chalcogens; D008670:Metals; D016877:Oxidants; D004121:Dimethyl Sulfoxide