title: Nodular Lymphocyte Predominant Hodgkin Lymphoma Presenting With Unilateral Orbital Involvement.
abstract: A 40-year-old white woman presented to her general ophthalmologist for swelling of the left upper eyelid that began approximately 6 months before. CT scan of the orbits with and without contrast demonstrated homogenous enhancement of the left lacrimal gland. Examination was notable for left hypoglobus and proptosis. The patient underwent left lateral orbitotomy with biopsy of the mass and frozen section analysis showed lymphoid infiltrates. Subsequent histopathologic diagnosis was consistent with nodular lymphocyte predominant Hodgkin lymphoma, a rare subtype of Hodgkin lymphoma that has only once been previously reported in the orbit. The authors review the case and the relevant literature.
authors.affiliation: *Department of Ophthalmology, †Department of Laboratory Medicine and Pathology, and ‡Department of Otolaryngology, University of Minnesota Medical School, Minneapolis, Minnesota, U.S.A.
authors.forename: Pradeep
authors.initials: P
authors.lastname: Mettu
authors.forename: Megan
authors.initials: M
authors.lastname: Griffith
authors.forename: Sophia
authors.initials: S
authors.lastname: Yohe
authors.forename: Andrew R
authors.initials: AR
authors.lastname: Harrison
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005094:Exophthalmos / Q000175:diagnosis; D005260:Female; D006689:Hodgkin Disease / Q000473:pathology*; D006801:Humans; D007765:Lacrimal Apparatus / Q000473:pathology; D009918:Orbital Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed