title: [Genome Wide Association Study:its theory and methodological review].
abstract: This review article describes the background and practical aspects for the Genome Wide Association Studies(GWAS). I introduce several softwares which are actually used in practice so that the readers could perform GWAS without difficulty. Imputation method is also explained. Finally, some comments are provided regarding advanced topics such as missing heritability or intergenic association signals affecting regulatory mechanisms.
authors.affiliation: Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Japan.
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Kamatani
mesh_terms: D055106:Genome-Wide Association Study / Q000379:methods*; D006801:Humans; D012984:Software