title: Fragrant Sesquiterpene Ketones as Trace Constituents in Frankincense Volatile Oil of Boswellia sacra.
abstract: In a previous study, two highly potent yet unidentified odorants were detected that were present at trace levels in the volatile fraction of Boswellia sacra gum resin. These two compounds were isolated semipreparatively from the volatile oil by a sensory-guided fractionation process involving microscale bulb-to-bulb distillation, countercurrent chromatography, and preparative gas chromatography. In this manner, the two oxygenated sesquiterpenes could be identified as rotundone (1) and mustakone (2). Compound 2 is described for the first time as a potent odorant with a very low odor threshold.
authors.affiliation: Department of Chemistry and Pharmacy, Food Chemistry, Emil Fischer Center, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) , Schuhstraße 19, 91052 Erlangen, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Niebler
authors.affiliation: Department of Chemistry and Pharmacy, Food Chemistry, Emil Fischer Center, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) , Schuhstraße 19, 91052 Erlangen, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Zhuravlova
authors.affiliation: Biothermodynamics, TUM School of Life Sciences Weihenstephan, Technische Universität München , Gregor-Mendel Straße 4, 85354 Freising, Germany.
authors.forename: Mirjana
authors.initials: M
authors.lastname: Minceva
authors.affiliation: Department of Chemistry and Pharmacy, Food Chemistry, Emil Fischer Center, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) , Schuhstraße 19, 91052 Erlangen, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Buettner
mesh_terms: D029743:Boswellia / Q000737:chemistry*; D065260:Frankincense / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D005858:Germany; D007659:Ketones / Q000302:isolation & purification*; D015394:Molecular Structure; D009812:Odorants / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry*; D012116:Resins, Plant / Q000737:chemistry; D012717:Sesquiterpenes / Q000032:analysis* / Q000737:chemistry
chemical_list: D007659:Ketones; D009822:Oils, Volatile; D012116:Resins, Plant; D012717:Sesquiterpenes; C000610614:mustakone; C530290:rotundone; D065260:Frankincense