title: [Obstructive sleep apnea syndrome: Metabolic complications].
abstract: Strongly linked to the presence of obesity, the obstructive sleep apnea syndrome is an independent risk factor for abnormalities of glucose metabolism ranging from simple impaired glucose tolerance to type 2 diabetes. It is also a risk factor for dyslipidemia, metabolic syndrome and non-alcoholic fatty liver disease. The pathological mechanisms underlying these associations remain to be precisely discovered, but intermittent hypoxia is probably one of the major factors. The place of obstructive apnea treatment in the management of metabolic conditions remains unclear.
authors.affiliation: Université Pierre-et-Marie-Curie, 47, boulevard de l'Hôpital, 75651 Paris, France. Electronic address: eofrija@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Frija-Orvoën
mesh_terms: D045422:Continuous Positive Airway Pressure; D003924:Diabetes Mellitus, Type 2 / Q000209:etiology; D050171:Dyslipidemias / Q000209:etiology; D006801:Humans; D008659:Metabolic Diseases / Q000209:etiology* / Q000517:prevention & control; D024821:Metabolic Syndrome / Q000209:etiology; D065626:Non-alcoholic Fatty Liver Disease / Q000209:etiology; D009765:Obesity / Q000209:etiology; D012307:Risk Factors; D020181:Sleep Apnea, Obstructive / Q000150:complications* / Q000628:therapy
keywords: Continuous positive airway pressure; Diabète de type 2; Dyslipidemia; Dyslipidémie; Fatty liver; Obstructive sleep apnea syndrome; Pression positive continue; Stéatose hépatique; Syndrome des apnées obstructives du sommeil; Type 2 diabetes