title: Epithelioid Hemangioendothelioma: a Rare Primary Thyroid Tumor with Confirmation of WWTR1 and CAMTA1 Rearrangements.
abstract: We report a rare case of epithelioid hemangioendothelioma as a primary thyroid tumor. To our knowledge, there are only two prior unequivocal cases of primary thyroid epithelioid hemangioendothelioma reported in the English literature. This is the first case in the thyroid with molecular confirmation.
authors.affiliation: Department of Pathology, University of Pittsburgh Medical Center, Presbyterian Rm. A609 200 Lothrop St, Pittsburgh, PA, 15213, USA. akeeshaashah@gmail.com.
authors.forename: Akeesha A
authors.initials: AA
authors.lastname: Shah
authors.affiliation: Department of Pathology, University of Pittsburgh Medical Center, Presbyterian Rm. A609 200 Lothrop St, Pittsburgh, PA, 15213, USA.
authors.forename: N Paul
authors.initials: NP
authors.lastname: Ohori
authors.affiliation: Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
authors.forename: Linwah
authors.initials: L
authors.lastname: Yip
authors.affiliation: Division of Endocrinology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Coyne
authors.affiliation: Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
authors.forename: Cristina R
authors.initials: CR
authors.lastname: Antonescu
authors.affiliation: Department of Pathology, University of Pittsburgh Medical Center, Presbyterian Rm. A609 200 Lothrop St, Pittsburgh, PA, 15213, USA.
authors.forename: Raja R
authors.initials: RR
authors.lastname: Seethala
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002135:Calcium-Binding Proteins / Q000235:genetics; D005260:Female; D015321:Gene Rearrangement; D018323:Hemangioendothelioma, Epithelioid / Q000235:genetics* / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D017404:In Situ Hybridization, Fluorescence; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics; D013964:Thyroid Neoplasms / Q000235:genetics* / Q000473:pathology*; D015534:Trans-Activators / Q000235:genetics; D014157:Transcription Factors; D000091364:Transcriptional Coactivator with PDZ-Binding Motif Proteins
chemical_list: D014408:Biomarkers, Tumor; C487554:CAMTA1 protein, human; D002135:Calcium-Binding Proteins; D047908:Intracellular Signaling Peptides and Proteins; D015534:Trans-Activators; D014157:Transcription Factors; D000091364:Transcriptional Coactivator with PDZ-Binding Motif Proteins; C551991:WWTR1 protein, human
keywords: Epithelioid hemangioendothelioma; Sarcoma; Thyroid; Vascular; WWTR1-CAMTA1