title: Carotid siphon morphology: Is it associated with posterior communicating aneurysms?
abstract: OBJECTIVE
  Posterior communicating artery (PComA) aneurysm seems to behave uniquely compared with other intracranial aneurysms at different locations. The association between the morphology of the carotid siphon and PComA aneurysms is not well known. This study aimed to investigate whether the anatomical characteristics of the carotid siphon are associated with the formation and rupture of PComA aneurysms.
  
  
  METHODS
  One hundred and thirty-two patients were retrospectively reviewed in a monocentric case-control study. Sixty-seven consecutive patients with PComA aneurysms were included in the case group, and 65 patients with anterior circulation aneurysm situated in other intracranial locations were included in the control group, matched by age and sex. Morphological characteristics of the carotid siphon were analyzed using angiography images. A univariate analysis was used to investigate the association between the morphological characteristics and the formation of PComA aneurysms. Furthermore, a subgroup analysis within the case group compared ruptured and non-ruptured PComA aneurysms.
  
  
  RESULTS
  Patients with PComA aneurysm had a significantly (1.31 ± 0.70 vs. 0.82 ± 0.46; P < 0.001) larger PComA. No association was observed between the morphological characteristics of the carotid siphon and the presence of a PComA aneurysm. Likewise, subgroup analysis showed no significant association between morphological characteristics of the carotid siphon and aneurysm rupture.
  
  
  CONCLUSIONS
  This case-control study shows that the carotid siphon morphology seems not to be related to PComA aneurysm formation or rupture.
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Paul-Emile
authors.initials: PE
authors.lastname: Labeyrie
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Gory
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Nazyad
authors.initials: N
authors.lastname: Huguet
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Grenier
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Geoffroy
authors.initials: G
authors.lastname: Ditac
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Udi
authors.initials: U
authors.lastname: Sadeh-Gonik
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France.
authors.forename: Roberto
authors.initials: R
authors.lastname: Riva
authors.affiliation: Department of Interventional Neuroradiology, Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, France francis.turjman@chu-lyon.fr.
authors.forename: Francis
authors.initials: F
authors.lastname: Turjman
mesh_terms: D015901:Angiography, Digital Subtraction; D002340:Carotid Artery Diseases / Q000150:complications* / Q000000981:diagnostic imaging; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging / Q000473:pathology*; D016022:Case-Control Studies; D002533:Cerebral Angiography; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Brain aneurysm; carotid artery; morphology; pathophysiology