title: Detection of Vaccine-Induced Antibodies to Ebola Virus in Oral Fluid.
abstract: Blood sampling to assess production of antigen-specific antibodies after immunization is commonly performed, but it presents logistical difficulties for trials carried out during an infectious disease outbreak. In this study, we show that antibodies may be reliably detected in oral fluid collected in a minimally invasive manner without use of sharps. Clinical Trials Registration. NCT02240875.
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Teresa
authors.initials: T
authors.lastname: Lambe
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Tommy
authors.initials: T
authors.lastname: Rampling
authors.affiliation: Virus Reference Department , National Infection Service, Public Health England.
authors.forename: Dhan
authors.initials: D
authors.lastname: Samuel
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Georgina
authors.initials: G
authors.lastname: Bowyer
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Katie J
authors.initials: KJ
authors.lastname: Ewer
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Navin
authors.initials: N
authors.lastname: Venkatraman
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Matthew
authors.initials: M
authors.lastname: Edmans
authors.affiliation: Transfusion Microbiology , National Health Service Blood and Transport , Colindale, London , United Kingdom.
authors.forename: Steve
authors.initials: S
authors.lastname: Dicks
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Adrian V S
authors.initials: AV
authors.lastname: Hill
authors.affiliation: Virus Reference Department , National Infection Service, Public Health England.
authors.forename: Richard S
authors.initials: RS
authors.lastname: Tedder
authors.affiliation: Jenner Institute , University of Oxford.
authors.forename: Sarah C
authors.initials: SC
authors.lastname: Gilbert
keywords: Ebola vaccine; antibodies; oral fluid; serology