title: Low-Grade Myofibroblastic Sarcoma in the Mandibular Canal: A Case Report.
abstract: Low-grade myofibroblastic sarcoma (LGMS) represents an atypical myofibroblastic tumor characterized by a diffusely infiltrating pattern of spindle-shaped tumor cells. It was classified as a distinct soft tissue tumor by the World Health Organization in 2002. LGMS occurs mostly in adult patients and has a predilection for the head and neck region. So far, only a few cases of LGMS located in the mandible have been reported. Aggressive surgical resection with clear margins is the primary treatment for LGMS. Because of its rarity, reports of radiation therapy are limited, and the therapeutic effect is still controversial. We present the case of an 8-year-old girl with LGMS of the mandibular canal to highlight the clinical features and rarity and to improve the understanding of the therapeutic effect of radiotherapy on LGMS.
authors.affiliation: Resident and Oral Surgeon, Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, China. Electronic address: 275577782@qq.com.
authors.forename: Yueyuan
authors.initials: Y
authors.lastname: Yu
authors.affiliation: Attending Physician and Oral Surgeon, Department of Oral and Maxillofacial Surgery, School & Hospital of Stomatology, Wenzhou Medical University, Wenzhou, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Xiao
authors.affiliation: Clinical Professor, Department of Pathology, Second Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
authors.forename: Lan
authors.initials: L
authors.lastname: Wang
authors.affiliation: Radiotherapy Technician, Department of Radiotherapy, First Affiliated Hospital, Wenzhou Medical University, Wenzhou, China.
authors.forename: Guiqiang
authors.initials: G
authors.lastname: Yang
mesh_terms: D002648:Child; D003937:Diagnosis, Differential; D003952:Diagnostic Imaging; D017809:Fatal Outcome; D005260:Female; D005354:Fibrosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007150:Immunohistochemistry; D008339:Mandibular Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D009217:Myosarcoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D060787:Neoplasm Grading