title: A Central Line Care Maintenance Bundle for the Prevention of Central Line-Associated Bloodstream Infection in Non-Intensive Care Unit Settings.
abstract: OBJECTIVE To evaluate a central line care maintenance bundle to reduce central line-associated bloodstream infection (CLABSI) in non-intensive care unit settings. DESIGN Before-after trial with 12-month follow-up period. SETTING A 1,250-bed teaching hospital. PARTICIPANTS Patients with central lines on 8 general medicine wards. Four wards received the intervention and 4 served as controls. INTERVENTION A multifaceted catheter care maintenance bundle consisting of educational programs for nurses, update of hospital policies, visual aids, a competency assessment, process monitoring, regular progress reports, and consolidation of supplies necessary for catheter maintenance. RESULTS Data were collected for 25,542 catheter-days including 43 CLABSI (rate, 1.68 per 1,000 catheter-days) and 4,012 catheter dressing observations. Following the intervention, a 2.5% monthly decrease in the CLABSI incidence density was observed on intervention floors but this was not statistically significant (95% CI, -5.3% to 0.4%). On control floors, there was a smaller but marginally significant decrease in CLABSI incidence during the study (change in monthly rate, -1.1%; 95% CI, -2.1% to -0.1%). Implementation of the bundle was associated with improvement in catheter dressing compliance on intervention wards (78.8% compliance before intervention vs 87.9% during intervention/follow-up; P<.001) but improvement was also observed on control wards (84.9% compliance before intervention vs 90.9% during intervention/follow-up; P=.001). CONCLUSIONS A multifaceted program to improve catheter care was associated with improvement in catheter dressing care but no change in CLABSI rates. Additional study is needed to determine strategies to prevent CLABSI in non-intensive care unit patients. Infect Control Hosp Epidemiol 2016;37:692-698.
authors.affiliation: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors.forename: Caroline
authors.initials: C
authors.lastname: O'Neil
authors.affiliation: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors.forename: Kelly
authors.initials: K
authors.lastname: Ball
authors.affiliation: 2Barnes-Jewish Hospital,St. Louis,Missouri.
authors.forename: Helen
authors.initials: H
authors.lastname: Wood
authors.affiliation: 2Barnes-Jewish Hospital,St. Louis,Missouri.
authors.forename: Kathleen
authors.initials: K
authors.lastname: McMullen
authors.affiliation: 2Barnes-Jewish Hospital,St. Louis,Missouri.
authors.forename: Pamala
authors.initials: P
authors.lastname: Kremer
authors.affiliation: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors.forename: S Reza
authors.initials: SR
authors.lastname: Jafarzadeh
authors.affiliation: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors.forename: Victoria
authors.initials: V
authors.lastname: Fraser
authors.affiliation: 1Division of Infectious Diseases,Washington University School of Medicine,St. Louis,Missouri.
authors.forename: David
authors.initials: D
authors.lastname: Warren
mesh_terms: D055499:Catheter-Related Infections / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects* / Q000379:methods; D003428:Cross Infection / Q000517:prevention & control*; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D064872:Patient Care Bundles / Q000379:methods*