title: Intraductal papillary mucinous neoplasm presenting with recurrent pancreatitis: a report of a painful 3-decade-long history.
abstract: Intraductal papillary mucinous neoplasm represents the most common pancreatic cystic neoplasm and harbours significant malignant potential. Duct obliteration can lead to recurrent episodes of pancreatic inflammation mimicking acute and chronic pancreatitis. We report a case of a patient with multiple episodes of idiopathic pancreatitis occurring over a period of three decades. Following admission with severe upper gastrointestinal bleeding, the patient was diagnosed as having invasive pancreatic adenocarcinoma. Examination of the surgical specimen confirmed an intraductal papillary mucinous neoplasm with multiple foci of invasive adenocarcinoma. This case is of significant interest, highlighting the long delay until diagnosis seen in this situation. Intraductal papillary mucinous neoplasm should be considered in the presence of recurrent acute or chronic pancreatitis of unknown aetiology.
authors.affiliation: Serviço de Gastrenterologia e Hepatologia, Hospital de Santa Maria, Lisbon, Portugal.
authors.forename: Samuel Raimundo
authors.initials: SR
authors.lastname: Fernandes
authors.affiliation: Serviço de Gastrenterologia e Hepatologia, Hospital de Santa Maria, Lisbon, Portugal.
authors.forename: Luís Araújo
authors.initials: LA
authors.lastname: Correia
authors.affiliation: Serviço de Gastrenterologia e Hepatologia, Hospital de Santa Maria, Lisbon, Portugal.
authors.forename: Teresa
authors.initials: T
authors.lastname: Antunes
authors.affiliation: Serviço de Gastrenterologia e Hepatologia, Hospital de Santa Maria, Lisbon, Portugal.
authors.forename: Helena
authors.initials: H
authors.lastname: Cortez-Pinto
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D000368:Aged; D021441:Carcinoma, Pancreatic Ductal / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D003937:Diagnosis, Differential; D016099:Endoscopy, Gastrointestinal; D006801:Humans; D008297:Male; D010190:Pancreatic Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery; D050500:Pancreatitis, Chronic / Q000209:etiology*; D016896:Treatment Outcome