title: Diffusion-Weighted Imaging of Small Peritoneal Implants in "Potentially" Early-Stage Ovarian Cancer.
abstract: BACKGROUND
  MRI is established modality for the diagnosis of ovarian malignancies. Advances in MRI technology, including DW imaging, could lead to the further increase in the sensitivity of MRI for the detection of peritoneal metastases. The aim of this study was to assess the accuracy of DW imaging for detection of peritoneal metastatic disease in patients suspected of having potentially early ovarian cancer and secondly to evaluate ADC values of peritoneal implants.
  
  
  METHODS
  The prospective study group consisted of 26 women with sonographic or/and CT diagnosis of suspected ovarian tumor. Based on the results of the above imaging, in none of them was extraovarian spread of disease or ascites recognized. All patients underwent MRI with DW imaging.
  
  
  RESULTS
  Overall, 18 extraovarian peritoneal lesions were found on DW images in 10 from 26 examined patients. All implants had diameter ≤10 mm. The presence of all lesions diagnosed by MRI was confirmed intraoperatively. Histopathologic findings in 17 proofs confirmed ovarian cancer. PPV was 94%. On all DW images (with b values of 0, 50, 100, 150, 200, 400, 800, and 1200 s/mm(2)) the mean signal intensities of peritoneal lesions were significantly higher than the mean signal intensities of normal adjacent tissue (p = 0.000001).
authors.affiliation: 2nd Department of Clinical Radiology, Medical University of Warsaw, Banacha 1a Street, 02-097 Warsaw, Poland.
authors.forename: Laretta
authors.initials: L
authors.lastname: Grabowska-Derlatka
authors.affiliation: 2nd Department of Obstetrics and Gynecology, Medical University of Warsaw, Karowa 2 Street, 00-315 Warsaw, Poland.
authors.forename: Pawel
authors.initials: P
authors.lastname: Derlatka
authors.affiliation: 2nd Department of Clinical Radiology, Medical University of Warsaw, Banacha 1a Street, 02-097 Warsaw, Poland.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Szeszkowski
authors.affiliation: 2nd Department of Clinical Radiology, Medical University of Warsaw, Banacha 1a Street, 02-097 Warsaw, Poland; Department of Radiology I, Maria Sklodowska-Curie Memorial Cancer Center, Institute of Oncology, Roentgena 5 Street, 02-781 Warsaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Cieszanowski
mesh_terms: D000328:Adult; D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D006801:Humans; D008875:Middle Aged; D009362:Neoplasm Metastasis; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging*; D010534:Peritoneal Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary*; D011446:Prospective Studies; D019736:Prostheses and Implants