title: Survival of Dental Implants Placed in Grafted and Nongrafted Bone: A Retrospective Study in a University Setting.
abstract: OBJECTIVE
  To compare dental implant survival rates when placed in native bone and grafted sites. Additionally, risk factors associated with dental implant loss were identified. This study was based on the hypothesis that bone grafting has no effect on implant survival rates.
  
  
  METHODS
  A retrospective chart review was conducted for patients receiving dental implants at the University of Texas, School of Dentistry from 1985 to 2012. Exclusion criteria included patients with genetic diseases, radiation and chemotherapy, or an age less than 18 years. To avoid misclassification bias, implants were excluded if bone grafts were only done at the same time of placement. Data on age, sex, tobacco use, diabetes, osteoporosis, anatomical location of the implant, implant length and width, bone graft, and professional maintenance were collected for analysis.
  
  
  RESULTS
  A total of 1,222 patients with 2,729 implants were included. The cumulative survival rates at 5 and 10 years were 92% and 87% for implants placed in native bone and 90% and 79% for implants placed in grafted bone, respectively. The results from multivariate analysis (Cox regression) indicated no significant difference in survival between the two groups; having maintenance therapy after implant placement reduced the failure rate by 80% (P < .001), and using tobacco increased the failure rate by 2.6-fold (P = .001).
  
  
  CONCLUSIONS
  There was no difference in the dental implant survival rate when implants were placed in native bone or bone-grafted sites. Smoking and lack of professional maintenance were significantly related to increased implant loss.
authors.forename: Duong T
authors.initials: DT
authors.lastname: Tran
authors.forename: Isabel C
authors.initials: IC
authors.lastname: Gay
authors.forename: Janice
authors.initials: J
authors.lastname: Diaz-Rodriguez
authors.forename: Kavitha
authors.initials: K
authors.lastname: Parthasarathy
authors.forename: Robin
authors.initials: R
authors.lastname: Weltman
authors.forename: Lawrence
authors.initials: L
authors.lastname: Friedman
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000540:Alveolar Ridge Augmentation / Q000379:methods / Q000706:statistics & numerical data*; D016025:Bone Transplantation / Q000379:methods / Q000706:statistics & numerical data*; D003758:Dental Implantation, Endosseous / Q000379:methods / Q000706:statistics & numerical data*; D015921:Dental Implants / Q000706:statistics & numerical data*; D019232:Dental Restoration Failure / Q000706:statistics & numerical data; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008334:Mandible / Q000601:surgery; D008437:Maxilla / Q000601:surgery; D008875:Middle Aged; D010024:Osteoporosis / Q000453:epidemiology; D012189:Retrospective Studies; D012907:Smoking / Q000453:epidemiology; D016019:Survival Analysis; D013781:Texas / Q000453:epidemiology; D055815:Young Adult
chemical_list: D015921:Dental Implants