title: The role of orthobiologics in hip preservation surgery.
abstract: The potential regenerative role of different orthobiologics is becoming more recognized for the treatment of chronic and degenerative musculoskeletal conditions. Over the last few years there has been an increasing number of publications on cell therapy and other orthobiologics for the treatment of avascular necrosis of the femoral head and other hip conditions with promising short-term clinical results. In this article, we have used a systematic search of the literature to identify potentially relevant topics on orthobiologics and then selected those most applicable to hip preservation surgery. We identified several innovative strategies and present a summary of the currently available evidence on their potential role in hip preservation surgery. For many of these treatment strategies there was a lack of clinical evidence and therefore we suggest that there is a need for comparative studies in this field.
authors.affiliation: 1. Health Education East of England, 2-4 victoria house, Cambridge, CB21 5XB.
authors.forename: Zeiad
authors.initials: Z
authors.lastname: Alshameeri
authors.affiliation: 2. Division of Trauma and Orthopaedic Surgery, Department of Surgery, University of Cambridge and; 3. Arthritis Research UK Tissue Engineering Centre.
authors.forename: Andrew
authors.initials: A
authors.lastname: McCaskie