title: Effect of endoleaks on changes in aortoiliac volume after endovascular repair for abdominal aortic aneurysm.
abstract: OBJECTIVE
  To evaluate changes in aortoiliac volume after endovascular repair (EVAR) for abdominal aortic aneurysm (AAA) in patients with and without endoleaks.
  
  
  METHODS
  We retrospectively analyzed 137 patients who underwent EVAR for AAA. We manually measured the aortoiliac volume on pre-procedural baseline CT angiograms (CTAs) and post-procedural follow-up CTAs. All post-procedural CTAs were evaluated for the presence of endoleaks. Follow-up examinations were grouped into five time points relative to the date of the EVAR procedure and mean aortoiliac volume changes from the baseline were calculated.
  
  
  RESULTS
  In 51 patients (37.2%), endoleaks were detected during follow-up. In patients without any endoleaks, mean aortoiliac volume decreased by 21.1% from the pre-interventional baseline examination to the last follow-up examination. In patients with any endoleak during follow-up aortoiliac volume increased by 12.2% and in patients with only transient, post-procedural endoleaks (n = 18), aortoiliac volume decreased by 13.4% over the same time period.
  
  
  CONCLUSIONS
  After EVAR for AAA, aortoiliac volume on CT angiography decreases by approximately 20% over time in the absence of endoleaks and increases in the presence of endoleaks. Transient post-procedural endoleaks, however, do not influence long-term volume regression.
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Felix G
authors.initials: FG
authors.lastname: Meinel
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Mareike
authors.initials: M
authors.lastname: Haack
authors.affiliation: Department of Vascular and Endovascular Surgery, Munich Municipal Hospital Group, Klinikum Neuperlach, Munich, Germany.
authors.forename: Rolf
authors.initials: R
authors.lastname: Weidenhagen
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Katharina
authors.initials: K
authors.lastname: Hellbach
authors.affiliation: Institute for Medical Information Sciences, Biometry and Epidemiology, Munich, Germany.
authors.forename: Marietta
authors.initials: M
authors.lastname: Rottenkolber
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Marco
authors.initials: M
authors.lastname: Armbruster
authors.affiliation: Department of Vascular Surgery, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Jerkku
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Kolja M
authors.initials: KM
authors.lastname: Thierfelder
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Jessica L V
authors.initials: JL
authors.lastname: Plum
authors.affiliation: Department of Vascular Surgery, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Koeppel
authors.affiliation: Department of Radiology, Duke University, Durham, NC, USA.
authors.forename: Geoffrey D
authors.initials: GD
authors.lastname: Rubin
authors.affiliation: Institute for Clinical Radiology, Ludwig-Maximilians-University Hospital, Munich, Germany.
authors.forename: Wieland H
authors.initials: WH
authors.lastname: Sommer
mesh_terms: D000368:Aged; D017544:Aortic Aneurysm, Abdominal / Q000150:complications*; D057867:Endoleak / Q000276:immunology*; D057510:Endovascular Procedures / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D016896:Treatment Outcome
keywords: Endovascular repair; abdominal aortic aneurysm; computed tomography angiography; endoleaks; volumetric analysis