title: Clinical Significance of a Novel Knee Joint Stability Assessment System for Evaluating Anterior Cruciate Ligament Deficient Knees.
abstract: OBJECTIVE
  To investigate the six degrees of freedom (6DOF) kinematics of anterior cruciate ligament (ACL) deficient knees during gait and to explore the clinical significance of a novel knee joint stability assessment system (Opti_Knee, Innomotion, Shanghai, China) in comparison with imaging and arthroscopic examination.
  
  
  METHODS
  Three subjects diagnosed with ACL deficient knees on the basis of preoperative MRI and CT findings were subjected to treadmill gait analysis. Motion of both knees in 6DOF was measured and analyzed with an optical joint kinematics measurement system. Arthroscopic examination, the gold standard, was performed to confirm the final diagnosis and the clinical diagnosis of ACL deficiency by imaging and motion marker techniques compared with this gold standard.
  
  
  RESULTS
  Only two of the three subjects diagnosed with ACL deficiency by imaging techniques were later confirmed to have this condition by arthroscopic examination; the third was found to have an intact ACL. When the kinematics of their injured and contralateral knees were compared, abnormalities were found in the two subjects confirmed by arthroscopy to be ACL deficient However, no kinematic difference between the two knees was found in the ACL intact subject.
  
  
  CONCLUSIONS
  Opti_Knee (Innomotion) can detect abnormal kinematics in ACL deficient knees and thus provides an effective way of assisting the diagnosis of this condition and has potential for clinical application.
authors.affiliation: Southern Medical University, Guangzhou, Guangdong, China.|Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Zi-long
authors.initials: ZL
authors.lastname: Yao
authors.affiliation: Key Laboratory of Exercise and Health Science, Ministry of Education, Shanghai University of Sport, Shanghai, China.
authors.forename: Shao-bai
authors.initials: SB
authors.lastname: Wang
authors.affiliation: Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Wen-han
authors.initials: WH
authors.lastname: Huang
authors.affiliation: Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Hong-yuan
authors.initials: HY
authors.lastname: Shen
authors.affiliation: Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Li-min
authors.initials: LM
authors.lastname: Ma
authors.affiliation: Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Hua-yang
authors.initials: HY
authors.lastname: Huang
authors.affiliation: Department of Orthopaedic Surgery, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.|Department of Orthopedics, Guangdong Key Lab of Orthopaedic Technology and Implant, Guangzhou General Hospital of Guangzhou Military Command, Guangzhou, Guangdong, China.
authors.forename: Hong
authors.initials: H
authors.lastname: Xia
mesh_terms: D000328:Adult; D016118:Anterior Cruciate Ligament / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001182:Arthroscopy; D001696:Biomechanical Phenomena; D005684:Gait; D006801:Humans; D007593:Joint Instability / Q000175:diagnosis* / Q000503:physiopathology; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000503:physiopathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D016059:Range of Motion, Articular; D014057:Tomography, X-Ray Computed
keywords: Anterior cruciate ligament; Gait analysis; Kinematics; Knee