title: Signs of hydroxychloroquine toxicity in a patient with rhegmatogenous retinal detachment.
abstract: METHODS
  The case is presented of a 56 year-old patient diagnosed with rhegmatogenous retinal detachment and on treatment with hydroxychloroquine (HCQ). A Spectral Domain-Optical Coherence Tomography (SD-OCT) was performed that showed changes in the outer retina in the eye with macular detachment, as well as the «flying saucer» sign in the other eye. After a complete retinopexy the «flying saucer» sign was still present.
  
  
  CONCLUSIONS
  SD-OCT could be used as a test in order to reveal HCQ toxicity in the event of retinal detachment. In this case, this technique shows abnormalities such as a hyper-reflective line in the outer retina layers.
authors.affiliation: Servicio de Oftalmología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: Campos-Pavón
authors.affiliation: Servicio de Oftalmología, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address: javiersambricio@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Sambricio
authors.affiliation: Servicio de Oftalmología, Hospital Universitario 12 de Octubre, Madrid, España.
authors.forename: I
authors.initials: I
authors.lastname: Redondo-García
mesh_terms: D005122:Exudates and Transudates; D015785:Eye Diseases, Hereditary / Q000188:drug therapy* / Q000601:surgery; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects*; D008028:Light Coagulation; D008266:Macula Lutea / Q000000981:diagnostic imaging* / Q000187:drug effects; D008875:Middle Aged; D061848:Optical Imaging; D012163:Retinal Detachment / Q000188:drug therapy* / Q000601:surgery; D012167:Retinal Perforations / Q000000981:diagnostic imaging* / Q000601:surgery; D055213:Retinal Pigment Epithelium / Q000000981:diagnostic imaging; D041623:Tomography, Optical Coherence; D014821:Vitrectomy
chemical_list: D006886:Hydroxychloroquine
keywords: Bull's eye maculopahty; Desprendimiento de retina; Flying saucer sign; Hydroxychloroquine retinopathy; Maculopatía en ojo de buey; Optical coherence tomography; Retinal detachment; Retinopatía por hidroxicloroquina; Signo del platillo volante; Tomografía de coherencia óptica