title: Dexmedetomidine: Superiority trials needed? Reply.
authors.affiliation: Department of perioperative medicine, University Hospital of Clermont-Ferrand, 63000 Clermont-Ferrand, France. Electronic address: jmconstantin@chu-clermontferrand.fr.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Constantin
authors.affiliation: Department of perioperative medicine, University Hospital of Clermont-Ferrand, 63000 Clermont-Ferrand, France.
authors.forename: Sebastien
authors.initials: S
authors.lastname: Perbet
mesh_terms: D058647:Adrenergic alpha-2 Receptor Agonists; D000070642:Brain Injuries, Traumatic / Q000150:complications / Q000628:therapy; D000075202:Contraindications; D003422:Critical Care; D054810:Deep Sedation / Q000379:methods; D020927:Dexmedetomidine; D006801:Humans; D006993:Hypnotics and Sedatives; D012128:Respiratory Distress Syndrome / Q000150:complications / Q000628:therapy
chemical_list: D058647:Adrenergic alpha-2 Receptor Agonists; D006993:Hypnotics and Sedatives; D020927:Dexmedetomidine
keywords: ARDS; Acute respiratory distress syndrome; Alpha-2 adrenergic agonists; Alpha-2 agonists; Clonidine; Critical care; Dexmedetomidine; Intracranial pressure; Sedation; Severe ARDS; Traumatic brain injury