title: [Detection of bocavirus in 4-week-old puppies with acute diarrhea].
abstract: Two 4-month-old female Doberman puppies were presented with clinical signs of acute diarrhea and emesis. They also showed sneezing and nasal discharge. The clinical presentation and neutropenia were suggestive of a parvovirus infection. The puppies were hospitalized for several days and treated symptomatically. Fecal samples tested negative for parasites. Virological examination of feces using polymerase chain reaction (PCR) and immune electron microscopy failed to confirm a parvovirus infection. With a recently developed PCR, bocavirus could be identified, thus making an infection with this virus a possible diagnosis. This case report presents a less well-known viral puppy disease and its successful therapy.
authors.affiliation: Sina Rudolf, Klinik für Kleintiere, Innere Medizin, Justus-Liebig-Universität Gießen, Frankfurter Straße 126, 35392 Gießen, E-Mail: sina.rudolf@vetmed.uni-giessen.de.
authors.forename: S
authors.initials: S
authors.lastname: Rudolf
authors.forename: R
authors.initials: R
authors.lastname: Neiger
authors.forename: M
authors.initials: M
authors.lastname: König
mesh_terms: D000818:Animals; D000897:Anti-Ulcer Agents / Q000627:therapeutic use; D000932:Antiemetics / Q000627:therapeutic use; D000998:Antiviral Agents / Q000627:therapeutic use; D052660:Bocavirus / Q000235:genetics / Q000302:isolation & purification*; D003967:Diarrhea / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary* / Q000821:virology; D004283:Dog Diseases / Q000175:diagnosis / Q000628:therapy / Q000821:virology*; D004285:Dogs; D004573:Electrolytes / Q000008:administration & dosage; D005243:Feces / Q000821:virology; D005260:Female; D007262:Infusions, Intravenous / Q000662:veterinary; D007372:Interferons / Q000627:therapeutic use; D010322:Parvoviridae Infections / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D054328:Proton Pump Inhibitors / Q000627:therapeutic use
chemical_list: D000897:Anti-Ulcer Agents; D000932:Antiemetics; D000998:Antiviral Agents; D004573:Electrolytes; D054328:Proton Pump Inhibitors; D007372:Interferons
keywords: Dog; PCR; bocavirus; nasal discharge; neutropenia