title: Solution Structures of Hauser Base (i)Pr2NMgCl and Turbo-Hauser Base (i)Pr2NMgCl·LiCl in THF and the Influence of LiCl on the Schlenk-Equilibrium.
abstract: Grignard reagents that are at the simplest level described as "RMgX" (where R is an organic substituent and X a halide) are one of the most widely utilized classes of synthetic reagents. Lately, especially Grignard reagents with amido ligands of the type R1R2NMgX, so-called Hauser bases, and their Turbo analogue R1R2NMgX·LiCl play an outranging role in modern synthetic chemistry. However, because of their complex solution behavior, where Schlenk-type equilibria are involved, very little is known about their structure in solution. Especially the impact of LiCl on the Schlenk-equilibrium was still obscured by complexity and limited analytical access. Herein, we present unprecedented insights into the solution structure of the Hauser base (i)Pr2NMgCl 1 and the Turbo-Hauser base (i)Pr2NMgCl·LiCl 2 at various temperatures in THF-d8 solution by employing a newly elaborated diffusion ordered spectroscopy (DOSY) NMR method hand-in-hand with theoretical calculations.
authors.affiliation: Institut für Anorganische Chemie, Georg-August-Universität , Tammannstrasse 4, D-37077 Göttingen, Germany.
authors.forename: Roman
authors.initials: R
authors.lastname: Neufeld
authors.affiliation: Institut für Physikalische Chemie, Georg-August-Universität , Tammannstrasse 6, D-37077 Göttingen, Germany.
authors.forename: Thorsten L
authors.initials: TL
authors.lastname: Teuteberg
authors.affiliation: Institut für Anorganische Chemie, Georg-August-Universität , Tammannstrasse 4, D-37077 Göttingen, Germany.
authors.forename: Regine
authors.initials: R
authors.lastname: Herbst-Irmer
authors.affiliation: Institut für Physikalische Chemie, Georg-August-Universität , Tammannstrasse 6, D-37077 Göttingen, Germany.
authors.forename: Ricardo A
authors.initials: RA
authors.lastname: Mata
authors.affiliation: Institut für Anorganische Chemie, Georg-August-Universität , Tammannstrasse 4, D-37077 Göttingen, Germany.
authors.forename: Dietmar
authors.initials: D
authors.lastname: Stalke