title: EVALUATION OF HEPATIC FUNCTION AMONG PATIENTS UNDERGOING TOTAL HIP ARTHROPLASTY USING ENOXAPARIN.
abstract: OBJECTIVE
  To evaluate hepatic changes resulting from the use of enoxaparin for prophylaxis of deep vein thrombosis among patients undergoing total hip arthroplasty.
  
  
  METHODS
  Thirty-two patients underwent elective total hip arthroplasty, using enoxaparin, and were followed up for 65 days with serial hepatic enzyme assays.
  
  
  RESULTS
  Changes in laboratory parameters were found in up to 75% of the patients during the study, but the parameters normalized after suspension of the treatment. No clinical evidence of hepatic lesions was found.
  
  
  CONCLUSIONS
  The hepatic enzyme levels increase in most patients using enoxaparin, but without clinical correlation, and the levels normalize after suspension of the treatment.
authors.affiliation: Resident Physician in the Orthopedics and Traumatology Service, Santa Casa Hospital Complex, Porto Alegre, RS, Brazil.
authors.forename: Felipe Vitiello
authors.initials: FV
authors.lastname: Wink
authors.affiliation: Titular Professor of the Discipline of Orthopedics and Traumatology, Foundation of the Federal School of Medical Sciences of Porto Alegre; Head of the Orthopedics and Traumatology Service, Santa Casa Hospital Complex, Porto Alegre, RS, Brazil.
authors.forename: Carlos Roberto
authors.initials: CR
authors.lastname: Schwartsmann
keywords: Arthroplasty, hip; Enoxaparin; Liver failure; Venous thrombosis