title: Programmed Bacteria Death Induced by Carbon Dots with Different Surface Charge.
abstract: Based on a series of biochemical experiments for analysis and characterization, it is found that the uncharged C-dots have no effect on bacterial growth while the negatively charged and positively charged C-dots can induce bacteria apoptosis. For the positively charged C-dots, they can induce both bacteria apoptosis and bacteria death. These observations will provide new insights into bioapplications of carbon dots.
authors.affiliation: College of Life Science, Jilin University, Changchun, Jilin, 130012, P. R. China.|Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Bing
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
authors.forename: Hanjun
authors.initials: H
authors.lastname: Sun
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
authors.forename: Zhengqing
authors.initials: Z
authors.lastname: Yan
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin, 130022, China. xqu@ciac.ac.cn.
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D002244:Carbon / Q000737:chemistry / Q000494:pharmacology*; D053938:DNA Fragmentation / Q000187:drug effects; D004926:Escherichia coli / Q000166:cytology* / Q000187:drug effects / Q000648:ultrastructure; D005453:Fluorescence; D005947:Glucose / Q000737:chemistry / Q000494:pharmacology; D050296:Microbial Viability / Q000187:drug effects*; D010718:Phosphatidylserines / Q000378:metabolism; D045663:Quantum Dots / Q000737:chemistry* / Q000648:ultrastructure; D013096:Spermine / Q000737:chemistry / Q000494:pharmacology; D055672:Static Electricity
chemical_list: D010718:Phosphatidylserines; D013096:Spermine; D002244:Carbon; D005947:Glucose
keywords: apoptosis; carbon dots; programmed cell death; surface charge