title: Dietary total antioxidant capacity is associated with plasmatic antioxidant capacity, nutrient intake and lipid and DNA damage in healthy women.
abstract: Dietary total antioxidant capacity (DTAC) seems to be associated with reducing risk of diseases. However, data about the influence of the DTAC on oxidative stress parameters are scarce. The aim of this study was to estimate the DTAC and its influence on plasma total antioxidant capacity (PTAC), and damage to lipids, proteins and DNA in healthy women. It was found a positive correlation between DTAC and PTAC in young and healthy subjects, where presumably the endogenous defenses are fully functional. DTAC and PTAC were positively correlated with the intake of known antioxidants, including vitamin C and polyphenols. The DTAC exhibited a negative correlation with lipid oxidative damage, while PTAC showed a negative correlation with DNA damage. This data contributes to better understanding of the recommended dietary antioxidant intake for promoting health.
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: Natalia
authors.initials: N
authors.lastname: Stedile
authors.affiliation: b Department of Social Medicine , Federal University of Rio Grande do Sul , Porto Alegre , RS , Brazil.
authors.forename: Raquel
authors.initials: R
authors.lastname: Canuto
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: Camila Dallavechia de
authors.initials: CD
authors.lastname: Col
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: Juliane Souza de
authors.initials: JS
authors.lastname: Sene
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: Adriana
authors.initials: A
authors.lastname: Stolfo
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: Gabrielle Nunes de Souza
authors.initials: GN
authors.lastname: Wisintainer
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: João Antonio Pêgas
authors.initials: JA
authors.lastname: Henriques
authors.affiliation: a Institute of Biotechnology , University of Caxias do Sul , Caxias do Sul , RS , Brazil ;
authors.forename: Mirian
authors.initials: M
authors.lastname: Salvador
mesh_terms: D000293:Adolescent; D000328:Adult; D000975:Antioxidants / Q000008:administration & dosage* / Q000032:analysis; D001205:Ascorbic Acid / Q000008:administration & dosage; D015415:Biomarkers / Q000097:blood; D001938:Brazil; D004249:DNA Damage; D000072001:Diet, Healthy; D015444:Exercise; D005260:Female; D000070497:Healthy Lifestyle; D006801:Humans; D006854:Hydrocortisone / Q000097:blood; D015227:Lipid Peroxidation; D018384:Oxidative Stress; D059808:Polyphenols / Q000008:administration & dosage; D050050:Protein Carbonylation; D057566:Self Report; D013315:Stress, Psychological / Q000097:blood / Q000503:physiopathology; D055815:Young Adult
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D059808:Polyphenols; D001205:Ascorbic Acid; D006854:Hydrocortisone
keywords: Antioxidants; diet; oxidative stress