title: Metabolic control of arthritis: Switch pathways to treat.
abstract: A shunting of glucose metabolism to the pentose phosphate pathway in rheumatoid arthritis T cells causes exhaustion of oxidants, enhanced cell proliferation, and differentiation toward the T helper 1 (TH1) and TH17 programs (Yanget al, this issue).
authors.affiliation: Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA. gtsokos@bidmc.harvard.edu.
authors.forename: George C
authors.initials: GC
authors.lastname: Tsokos
mesh_terms: D001172:Arthritis, Rheumatoid; D002454:Cell Differentiation; D006801:Humans; D018417:Th1 Cells / Q000378:metabolism*; D058504:Th17 Cells / Q000378:metabolism