title: Post-stroke dysphagia: A review and design considerations for future trials.
abstract: Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive complication of acute stroke and is associated with increased mortality, morbidity, and institutionalization due in part to aspiration, pneumonia, and malnutrition. Although most patients recover swallowing spontaneously, a significant minority still have dysphagia at six months. Although multiple advances have been made in the hyperacute treatment of stroke and secondary prevention, the management of dysphagia post-stroke remains a neglected area of research, and its optimal management, including diagnosis, investigation and treatment, have still to be defined.
authors.affiliation: Care of Older People, Northwick Park Hospital, UK.
authors.forename: David L
authors.initials: DL
authors.lastname: Cohen
authors.affiliation: Stroke Research, University Hospital of North Midlands, Keele University, UK.
authors.forename: Christine
authors.initials: C
authors.lastname: Roffe
authors.affiliation: Stroke, Royal Derby Hospital, UK.
authors.forename: Jessica
authors.initials: J
authors.lastname: Beavan
authors.affiliation: Nutrition, Salford Royal Hospital, UK.
authors.forename: Brenda
authors.initials: B
authors.lastname: Blackett
authors.affiliation: School of Psychology and Clinical Language Sciences, University of Reading, UK.
authors.forename: Carol A
authors.initials: CA
authors.lastname: Fairfield
authors.affiliation: Institute of Inflammation and Repair, University of Manchester, UK.
authors.forename: Shaheen
authors.initials: S
authors.lastname: Hamdy
authors.affiliation: Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, UK.
authors.forename: Di
authors.initials: D
authors.lastname: Havard
authors.affiliation: Speech and Language, Northwick Park Hospital, UK.
authors.forename: Mary
authors.initials: M
authors.lastname: McFarlane
authors.affiliation: Speech & Language, Royal Victoria Hospital, UK.
authors.forename: Carolee
authors.initials: C
authors.lastname: McLauglin
authors.affiliation: Neurology, Leeds Teaching Hospitals, UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Randall
authors.affiliation: Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, UK.
authors.forename: Katie
authors.initials: K
authors.lastname: Robson
authors.affiliation: Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, UK.
authors.forename: Polly
authors.initials: P
authors.lastname: Scutt
authors.affiliation: Stroke and Vascular Research Centre, University of Manchester, UK.
authors.forename: Craig
authors.initials: C
authors.lastname: Smith
authors.affiliation: Elderly Medicine, Princess Royal University Hospital, UK.
authors.forename: David
authors.initials: D
authors.lastname: Smithard
authors.affiliation: Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, UK.
authors.forename: Nikola
authors.initials: N
authors.lastname: Sprigg
authors.affiliation: Acute Stroke Unit, University Hospitals of North Midlands, UK.
authors.forename: Anushka
authors.initials: A
authors.lastname: Warusevitane
authors.affiliation: College of Health and Wellbeing, University of Central Lancashire, UK.
authors.forename: Caroline
authors.initials: C
authors.lastname: Watkins
authors.affiliation: Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, UK.
authors.forename: Lisa
authors.initials: L
authors.lastname: Woodhouse
authors.affiliation: Stroke Trials Unit, Division of Clinical Neuroscience, University of Nottingham, UK philip.bath@nottingham.ac.uk.
authors.forename: Philip M
authors.initials: PM
authors.lastname: Bath
mesh_terms: D003680:Deglutition Disorders / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control / Q000628:therapy*; D006801:Humans; D016032:Randomized Controlled Trials as Topic / Q000379:methods; D012107:Research Design; D020521:Stroke / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
keywords: Stroke; aspiration; design; dysphagia; pneumonia; randomized controlled trial; rehabilitation; treatment