title: UniProt Tools.
abstract: The Universal Protein Resource (UniProt) is a comprehensive resource for protein sequence and annotation data (UniProt Consortium, 2015). The UniProt Web site receives ∼400,000 unique visitors per month and is the primary means to access UniProt. Along with various datasets that you can search, UniProt provides three main tools. These are the 'BLAST' tool for sequence similarity searching, the 'Align' tool for multiple sequence alignment, and the 'Retrieve/ID Mapping' tool for using a list of identifiers to retrieve UniProtKB proteins and to convert database identifiers from UniProt to external databases or vice versa. This unit provides three basic protocols, three alternate protocols, and two support protocols for using UniProt tools.
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, United Kingdom.
authors.forename: Sangya
authors.initials: S
authors.lastname: Pundir
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, United Kingdom.
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Martin
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, United Kingdom.
authors.forename: Claire
authors.initials: C
authors.lastname: O'Donovan
authors.affiliation: European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Trust Genome Campus, Cambridge, United Kingdom.|Swiss Institute of Bioinformatics, University Medical Center, Geneva, Switzerland.|Protein Information Resource, Georgetown University Medical Center, Washington, D.C.|Protein Information Resource, University of Delaware, Newark, Delaware.
mesh_terms: D019295:Computational Biology / Q000379:methods*; D030562:Databases, Protein; D016247:Information Storage and Retrieval; D016415:Sequence Alignment
keywords: UniProt; navigation; search; tutorial