title: Postinfluenza Vaccination Idiopathic Thrombocytopenic Purpura in Three Elderly Patients.
abstract: The etiologies of secondary idiopathic thrombocytopenic purpura (ITP) include infection, autoimmune disease, and immunodeficiency. We report the cases of three elderly patients who developed ITP after receiving influenza vaccinations. The platelet count of an 81-year-old woman fell to 27,000/μL after she received an influenza vaccination. A 75-year-old woman developed thrombocytopenia (5,000 platelets/μL) after receiving an influenza vaccination. An 87-year-old woman whose laboratory test values included a platelet count of 2,000/μL experienced genital bleeding after receiving an influenza vaccination. After Helicobacter pylori (HP) eradication or corticosteroid treatment, all of the patients' platelet counts increased. Influenza vaccination is an underlying etiology of ITP in elderly patients. HP eradication or corticosteroid treatment is effective for these patients. Clinicians should be aware of the association between ITP and influenza vaccinations.
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Joji
authors.initials: J
authors.lastname: Nagasaki
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Manabe
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Ido
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Hiroyoshi
authors.initials: H
authors.lastname: Ichihara
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Aoyama
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Tadanobu
authors.initials: T
authors.lastname: Ohta
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Furukawa
authors.affiliation: Department of Hematology, Seichokai Fuchu Hospital, 1-10-17 Hikocho, Izumi-shi, Osaka 594-0076, Japan.
authors.forename: Atsuko
authors.initials: A
authors.lastname: Mugitani