title: Immobilization of two organometallic complexes into a single cage to construct protein-based microcompartments.
abstract: Natural protein-based microcompartments containing multiple enzymes promote cascade reactions within cells. We use the apo-ferritin protein cage to mimic such biocompartments by immobilizing two organometallic Ir and Pd complexes into the single protein cage. Precise locations of the metals and their accumulation mechanism were studied by X-ray crystallography.
authors.affiliation: Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, B-55, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. tueno@bio.titech.ac.jp.
authors.forename: Basudev
authors.initials: B
authors.lastname: Maity
authors.affiliation: Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, B-55, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. tueno@bio.titech.ac.jp.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Fukumori
authors.affiliation: Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, B-55, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. tueno@bio.titech.ac.jp.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Abe
authors.affiliation: Department of Biomolecular Engineering, Graduate School of Bioscience and Biotechnology, Tokyo Institute of Technology, B-55, 4259 Nagatsuta-cho, Midori-ku, Yokohama 226-8501, Japan. tueno@bio.titech.ac.jp.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Ueno
mesh_terms: D000818:Animals; D001052:Apoferritins / Q000737:chemistry*; D018360:Crystallography, X-Ray; D006736:Horses; D007495:Iridium / Q000737:chemistry*; D008958:Models, Molecular; D009942:Organometallic Compounds / Q000737:chemistry*; D010165:Palladium / Q000737:chemistry*
chemical_list: D009942:Organometallic Compounds; D007495:Iridium; D010165:Palladium; D001052:Apoferritins