title: Alterations in antioxidant/oxidant gene expression and proteins following treatment of transformed and normal colon cells with tellurium compounds.
abstract: The current study evaluated the potential of TeCl4 and DPDT to accumulate within cells and cause oxidative stress. HO-1, antioxidant gene expression and protein alterations were studied.
authors.affiliation: Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Jamaica, NY 11439, USA.
authors.forename: Puneet
authors.initials: P
authors.lastname: Vij
authors.affiliation: Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Jamaica, NY 11439, USA. Electronic address: hardejd@stjohns.edu.
authors.forename: Diane
authors.initials: D
authors.lastname: Hardej
mesh_terms: D000975:Antioxidants; D002460:Cell Line; D003106:Colon; D015870:Gene Expression; D015386:Hazardous Substances / Q000633:toxicity*; D051547:Heme Oxygenase-1 / Q000235:genetics; D006801:Humans; D016877:Oxidants; D018384:Oxidative Stress; D013691:Tellurium / Q000633:toxicity*; D018675:Toxicity Tests
chemical_list: D000975:Antioxidants; D015386:Hazardous Substances; D016877:Oxidants; C496541:HMOX1 protein, human; D051547:Heme Oxygenase-1; D013691:Tellurium
keywords: Metalloid accumulation; Oxidative stress; Tellurium