title: Advances in the Surgical Management of Resectable and Borderline Resectable Pancreas Cancer.
abstract: Successful surgical resection offers the only chance for cure in patients with pancreatic cancer. However, pancreatic resection is feasible in less than 20% of the patients. In this review, the current state of surgical management of pancreatic cancer is discussed. The definition of resectability based on cross-sectional imaging and the technical aspects of surgery, including vascular resection and/or reconstruction, management of aberrant vascular anatomy and extent of lymphadenectomy, are appraised. Furthermore, common pancreatic resection-specific postoperative complications and their management are reviewed.
authors.affiliation: Division of Surgical Oncology, Vanderbilt University Medical Center, 597 PRB, 2220 Pierce Avenue, Nashville, TN 37232, USA.
authors.forename: Beth A
authors.initials: BA
authors.lastname: Helmink
authors.affiliation: Department of Surgical Oncology, University of Texas M.D. Anderson Cancer Center, 1400 Pressler Street, Unit Number: 1484, Houston, TX 77030, USA.
authors.forename: Rebecca A
authors.initials: RA
authors.lastname: Snyder
authors.affiliation: Division of Surgical Oncology, Vanderbilt University Medical Center, 597 PRB, 2220 Pierce Avenue, Nashville, TN 37232, USA.
authors.forename: Kamran
authors.initials: K
authors.lastname: Idrees
authors.affiliation: Division of Surgical Oncology, Sylvester Comprehensive Cancer Center, University of Miami Medical Center, 1120 Northwest 14th Street, Clinical Research Building, Suite 410, Miami, FL 33136, USA.
authors.forename: Nipun B
authors.initials: NB
authors.lastname: Merchant
authors.affiliation: Division of Surgical Oncology, Vanderbilt University Medical Center, 597 PRB, 2220 Pierce Avenue, Nashville, TN 37232, USA. Electronic address: alexander.parikh@vanderbilt.edu.
authors.forename: Alexander A
authors.initials: AA
authors.lastname: Parikh
mesh_terms: D006801:Humans; D008197:Lymph Node Excision; D009364:Neoplasm Recurrence, Local / Q000401:mortality; D009367:Neoplasm Staging; D010179:Pancreas / Q000601:surgery*; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016577:Pancreaticoduodenectomy / Q000379:methods*
keywords: Aberrant vascular anatomy; Borderline resectable; Delayed gastric emptying; Lymphadenectomy; Palliation; Pancreatic fistula; Resectability; Vascular resection