title: Breast cancer patient with everolimus-induced angioedema: A rare occurrence with potential for serious consequences.
abstract: Background The development of angioedema is a rare yet serious clinical event that may develop due to an adverse drug reaction. Rapid recognition and treatment of this adverse reaction is critical for optimal patient outcomes; however, prevention of this occurrence is preferred. Case report A 59-year-old woman presented to the emergency department with lingual angioedema caused by the addition of everolimus to her medication regimen. The patient improved after withdrawal of the offending agent and standard treatment. Early recognition by healthcare providers and management of everolimus-induced angioedema is vital for successful patient outcomes. This report increases awareness of everolimus as a potentially causative agent for the development of angioedema.
authors.affiliation: Methodist University Hospital, Memphis, TN, USA.
authors.forename: Neil
authors.initials: N
authors.lastname: Roe
authors.affiliation: Methodist University Hospital, Memphis, TN, USA.
authors.forename: Jennifer D
authors.initials: JD
authors.lastname: Twilla
authors.affiliation: Methodist University Hospital, Memphis, TN, USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Duhart
authors.affiliation: Methodist University Hospital, Memphis, TN, USA.
authors.forename: Brian
authors.initials: B
authors.lastname: Wheeler
mesh_terms: D000799:Angioedema / Q000139:chemically induced*; D000970:Antineoplastic Agents / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy*; D000068338:Everolimus / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D000970:Antineoplastic Agents; D000068338:Everolimus
keywords: Angioedema; everolimus; lingual edema