title: Anaplastic Sarcoma of the Kidney: A Rare Unique Renal Neoplasm.
abstract: Anaplastic sarcoma of the kidney (ASK) is an extremely rare tumor, which usually presents as a large renal mass. Microscopically, the tumor is composed of pleomorphic mesenchymal spindle cells with marked atypia, associated with chondroid differentiation and focal round primitive mesenchymal cells. Herein, we present a case of anaplastic sarcoma of the kidney in a 3-year-old female, who presented with a large abdominal mass. To the best of our knowledge, less than 25 cases are reported in the literature. In addition, this is the first case reported from the Middle East.
authors.affiliation: Department of Pathology and Lab Medicine, King Abdullah International Medical Research Center / King Saud bin Abdulaziz University for Health Sciences, King Khaled National Guard Hospital, King Abdulaziz Medical City, Jeddah, Saudi Arabia mharabi@hotmail.com.
authors.forename: Haitham
authors.initials: H
authors.lastname: Arabi
authors.affiliation: Department of Pathology and Lab Medicine, King Abdullah International Medical Research Center / King Saud bin Abdulaziz University for Health Sciences, King Khaled National Guard Hospital, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
authors.forename: Hatim
authors.initials: H
authors.lastname: Al-Maghraby
authors.affiliation: Department of Pediatric Hematology Oncology, King Abdullah International Medical Research Center / King Saud bin Abdulaziz University for Health Sciences, King Khaled National Guard Hospital, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
authors.forename: Arwa
authors.initials: A
authors.lastname: Yamani
authors.affiliation: Department of Pediatric Surgery, King Abdullah International Medical Research Center / King Saud bin Abdulaziz University for Health Sciences, King Khaled National Guard Hospital, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
authors.forename: Yasmin
authors.initials: Y
authors.lastname: Yousef
authors.affiliation: Department of Pathology and Lab Medicine, King Abdullah International Medical Research Center / King Saud bin Abdulaziz University for Health Sciences, King Khaled National Guard Hospital, King Abdulaziz Medical City, Jeddah, Saudi Arabia.
authors.forename: Hassan
authors.initials: H
authors.lastname: Huwait
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007150:Immunohistochemistry; D007680:Kidney Neoplasms / Q000473:pathology*; D012509:Sarcoma / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: Wilms tumor; anaplastic sarcoma of the kidney; children; renal tumors