title: Epidemiology and Characteristics of Kikuchi-Fujimoto Disease in the African-Descent Population of Martinique, French West Indies.
abstract: To provide an epidemiologic description of Kikuchi-Fujimoto disease (KFD), and to describe its relationship with systemic lupus erythematosus (SLE) in a population of sub-Saharan origin.
  
  
  
  Patients were retrospectively included on the basis of lymph node histology compatible with KFD reported in Martinique from 1991 until 2013. In order to describe the characteristics of the disease in a larger cohort, we subsequently included more patients of Afro-Caribbean origin from Guadeloupe and French Guiana.
  
  
  
  In Martinique, mean annual incidence between 1991 and 2013 was 2.78 cases for 1 million inhabitants (95% confidence interval 1.73-3.93). A total of 36 Afro-Caribbean patients from the 3 French American regions were included. Mean age was 30.5 years (range 5-59 years) and the female:male ratio was 3:1. The main characteristics were cervical adenopathies (88.8%), fever (83.3%), asthenia (73.0%), weight loss (64.4%), and recurrence in 33.3%. KFD was associated with lupus (n = 9 for SLE, n = 2 for cutaneous lupus) in 36.6% (11 of 30).
  
  
  
  We report the first epidemiologic description of KFD in a population of sub-Saharan origin. According to our data, this disease is present in the black African diaspora and is strongly associated with autoimmune diseases, particularly lupus.
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Florence
authors.initials: F
authors.lastname: Moinet
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Vincent
authors.initials: V
authors.lastname: Molinié
authors.affiliation: Centre Hospitalier Universitaire de Poitiers, Poitiers, France.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Béraud
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Katlyne
authors.initials: K
authors.lastname: Polomat
authors.affiliation: Centre Centre Hospitalier Universitaire de Pointe-à-Pitre/Abymes, Pointe-à-Pitre, Guadeloupe.
authors.forename: Nadège
authors.initials: N
authors.lastname: Cordel
authors.affiliation: Dominique Sainte-Marie, MD, Centre Hospitalier André Rosemond, Cayenne, French Guiana.
authors.forename: Dominique
authors.initials: D
authors.lastname: Sainte-Marie
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Olivier
authors.initials: O
authors.lastname: Duffas
authors.affiliation: Centre Centre Hospitalier Universitaire de Pointe-à-Pitre/Abymes, Pointe-à-Pitre, Guadeloupe.
authors.forename: Suzy
authors.initials: S
authors.lastname: Duflo
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Charlène
authors.initials: C
authors.lastname: Bomahou
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Serge
authors.initials: S
authors.lastname: Arfi
authors.affiliation: Centre Hospitalier Universitaire Pierre Zobda Quitman, Fort de France, Martinique.
authors.forename: Christophe
authors.initials: C
authors.lastname: Deligny
mesh_terms: D000293:Adolescent; D000328:Adult; D044383:Black People / Q000706:statistics & numerical data*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005602:France / Q000208:ethnology; D020042:Histiocytic Necrotizing Lymphadenitis / Q000453:epidemiology* / Q000208:ethnology / Q000209:etiology; D006801:Humans; D015994:Incidence; D008180:Lupus Erythematosus, Systemic / Q000150:complications / Q000453:epidemiology / Q000208:ethnology; D008297:Male; D008395:Martinique / Q000453:epidemiology; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult