title: Imaging Features of Pulmonary CT in Type 2 Diabetic Patients with Multidrug-Resistant Tuberculosis.
abstract: BACKGROUND
  Until now, radiographic manifestations of multidrug-resistant pulmonary tuberculosis (MDR- TB) in patients with diabetes mellitus (DM) have not been reported. We conducted a study to investigate the imaging features of pulmonary computed tomography (CT) for type 2 diabetic (T2DM) patients with MDR-TB.
  
  
  METHODS
  The clinical data and pulmonary CT findings of 39 type 2 diabetic patients with MDR-TB, 46 type 2 diabetic patients with drug-susceptible tuberculosis (DS-TB), and 72 pure drug-susceptible TB cases (without T2DM and MDR) treated at Dalian Tuberculosis Hospital from 2012 to 2015 were collected, and the clinical features and imaging differences of the three groups were compared.
  
  
  RESULTS
  The clinical characteristics of the three groups of patients were not significantly different except with respect to age and previous treatment history. However, on imaging, the patients with MDR-TB showed consolidation in and above the pulmonary segments was significantly more extensive than that seen in the DS-TB group with or without T2DM.
  
  
  CONCLUSIONS
  Consolidation in or above multiple pulmonary segments with multiple mouth-eaten cavities and bronchial damage on pulmonary CT images in type 2 diabetic patients with tuberculosis suggests the possibility of multi-drug resistance.
authors.affiliation: Department of Internal Medicine, Dalian Tuberculosis Hospital, Liaoning, China.
authors.forename: Qisheng
authors.initials: Q
authors.lastname: Song
authors.affiliation: Department of Radiology, Dalian Tuberculosis Hospital, Liaoning, China.
authors.forename: Guoqing
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Department of Internal Medicine, Dalian Tuberculosis Hospital, Liaoning, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Jiang
authors.affiliation: Department of Internal Medicine, Dalian Tuberculosis Hospital, Liaoning, China.
authors.forename: Yanwei
authors.initials: Y
authors.lastname: Ren
authors.affiliation: Department of Internal Medicine, Dalian Tuberculosis Hospital, Liaoning, China.
authors.forename: Xiwei
authors.initials: X
authors.lastname: Lu
mesh_terms: D000328:Adult; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed; D018088:Tuberculosis, Multidrug-Resistant / Q000150:complications* / Q000000981:diagnostic imaging*