title: Surgery first in orthognathic surgery: A systematic review of the literature.
abstract: BACKGROUND
  Compared to the conventional approach to orthognathic surgery, "surgery first" protocols could be advantageous in terms of shortened treatment times and immediate esthetic improvement. However, consensus regarding patient selection, technical protocol, and stability is still lacking.
  
  
  METHODS
  A systematic review of the scientific literature on surgery-first treatment (January 2000 to January 2015) was performed. The PubMED and Cochrane Library databases were accessed. Patient selection criteria, specific surgical-orthodontic protocol, treatment duration, patient and orthodontist satisfaction, and stability of results were compared with a similar population treated conventionally.
  
  
  RESULTS
  The search yielded 179 publications. The application of strict selection criteria gave the final group of 11 articles. In total, 295 patients were managed with a surgery-first approach. A Class III malocclusion was the most prevalent underlying malocclusion (84.7%). Total treatment duration was shorter in surgery-first patients than in those treated conventionally. There was substantial heterogeneity among articles and high reporting bias regarding the inclusion and exclusion criteria, the orthodontic and surgical protocols, and the stability of results. A meta-analysis of combined data was not possible.
  
  
  CONCLUSIONS
  The surgery-first approach is a new treatment paradigm for the management of dentomaxillofacial deformity. Studies have reported satisfactory outcomes and high acceptance. However, the results should be interpreted with caution because of the wide varieties of study designs and outcome variables, reporting biases, and lack of prospective long-term follow-ups.
authors.affiliation: Fellow, International University of Catalonia, Barcelona, Spain.
authors.forename: María A
authors.initials: MA
authors.lastname: Peiró-Guijarro
authors.affiliation: Oral and maxillofacial surgeon, Institute of Maxillofacial Surgery, Teknon Medical Center Barcelona, Barcelona, Spain; assistant professor, Department of Oral and Maxillofacial Surgery, International University of Catalonia, Barcelona, Spain. Electronic address: guijarro.raq@gmail.com.
authors.forename: Raquel
authors.initials: R
authors.lastname: Guijarro-Martínez
authors.affiliation: Director, Institute of Maxillofacial Surgery, Teknon Medical Center Barcelona, Barcelona, Spain; chairman, Department of Oral and Maxillofacial Surgery, International University of Catalonia, Barcelona, Spain.
authors.forename: Federico
authors.initials: F
authors.lastname: Hernández-Alfaro
mesh_terms: D002985:Clinical Protocols; D063169:Dentofacial Deformities / Q000601:surgery / Q000628:therapy; D006801:Humans; D008313:Malocclusion, Angle Class III / Q000601:surgery / Q000628:therapy; D009971:Orthodontics, Corrective / Q000379:methods*; D056948:Orthognathic Surgical Procedures / Q000379:methods*; D017060:Patient Satisfaction; D018579:Patient Selection; D012008:Recurrence; D013997:Time Factors; D016896:Treatment Outcome