title: Transcatheter Arterial Embolization with n-Butyl Cyanoacrylate for the Treatment of Acquired Uterine Vascular Malformations.
abstract: OBJECTIVE
  The purpose of the study was to evaluate the technique and outcomes of transcatheter arterial embolization (TAE) with n-butyl cyanoacrylate (NBCA) for the treatment of acquired uterine arteriovenous malformations (AVMs).
  
  
  METHODS
  A retrospective review identified five women treated for suspected acquired uterine AVMs with TAE at our institution. Four women (80 %) presented with heavy or intermittent vaginal bleeding after obstetric manipulation. One woman (20 %) was treated for an incidental AVM discovered on ultrasound after an uncomplicated cesarean section. Three women underwent one embolization procedure and two women required two procedures. Embolization material included NBCA in six procedures (80 %) and gelatin sponge in one procedure (20 %).
  
  
  RESULTS
  Embolization resulted in angiographic stasis of flow in all seven procedures. Four women (80 %) presented with vaginal bleeding which was improved after treatment. One woman returned 24 days after unilateral embolization with recurrent bleeding, which resolved after retreatment. One woman underwent two treatments for an asymptomatic lesion identified on ultrasound. There were no major complications. Three women (60 %) experienced mild postembolization pelvic pain that was controlled with non-steroidal anti-inflammatory drugs. Three women (60 %) had pregnancies and deliveries after embolization.
  
  
  CONCLUSIONS
  TAE is a safe alternative to surgical therapy for acquired uterine AVMs with the potential to maintain fertility. Experience from this case series suggests that NBCA provides predictable and effective occlusion.
authors.affiliation: Department of Radiology, University of California, San Diego, 200 West Arbor Drive, San Diego, CA, 92103-8756, USA. apicel@ucsd.edu.
authors.forename: Andrew C
authors.initials: AC
authors.lastname: Picel
authors.affiliation: Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
authors.forename: Sonya J
authors.initials: SJ
authors.lastname: Koo
authors.affiliation: Department of Radiology, University of California, San Diego, 200 West Arbor Drive, San Diego, CA, 92103-8756, USA.
authors.forename: Anne C
authors.initials: AC
authors.lastname: Roberts
mesh_terms: D000328:Adult; D000792:Angiography; D001165:Arteriovenous Malformations / Q000150:complications / Q000628:therapy*; D002585:Cesarean Section; D004621:Embolization, Therapeutic / Q000379:methods*; D004659:Enbucrilate / Q000627:therapeutic use*; D005260:Female; D005780:Gelatin; D006801:Humans; D011247:Pregnancy; D019233:Retreatment; D012189:Retrospective Studies; D016896:Treatment Outcome; D014592:Uterine Hemorrhage / Q000150:complications / Q000628:therapy; D014599:Uterus / Q000098:blood supply*; D055815:Young Adult
chemical_list: D005780:Gelatin; D004659:Enbucrilate
keywords: Transcatheter arterial embolization; Uterine arteriovenous fistula; Uterine arteriovenous malformation; Uterine vascular malformation; n-Butyl cyanoacrylate