title: The AdaptiSPECT Imaging Aperture.
abstract: In this paper, we present the imaging aperture of an adaptive SPECT imaging system being developed at the Center for Gamma Ray Imaging (AdaptiSPECT). AdaptiSPECT is designed to automatically change its configuration in response to preliminary data, in order to improve image quality for a particular task. In a traditional pinhole SPECT imaging system, the characteristics (magnification, resolution, field of view) are set by the geometry of the system, and any modification can be accomplished only by manually changing the collimator and the distance of the detector to the center of the field of view. Optimization of the imaging system for a specific task on a specific individual is therefore difficult. In an adaptive SPECT imaging system, on the other hand, the configuration can be conveniently changed under computer control. A key component of an adaptive SPECT system is its aperture. In this paper, we present the design, specifications, and fabrication of the adaptive pinhole aperture that will be used for AdaptiSPECT, as well as the controls that enable autonomous adaptation.
authors.affiliation: College of Optical Sciences, University of Arizona.
authors.forename: Cécile
authors.initials: C
authors.lastname: Chaix
authors.affiliation: College of Optical Sciences, University of Arizona.
authors.forename: Jared W
authors.initials: JW
authors.lastname: Moore
authors.affiliation: Department of Electronics and Information Systems, Ghent University, Belgium.
authors.forename: Roel
authors.initials: R
authors.lastname: Van Holen
authors.affiliation: College of Optical Sciences, University of Arizona.
authors.forename: Harrison H
authors.initials: HH
authors.lastname: Barrett
authors.affiliation: College of Optical Sciences, University of Arizona.
authors.forename: Lars R
authors.initials: LR
authors.lastname: Furenlid
keywords: Imaging; SPECT; collimator design; instrumentation; small-animal