title: Hesperidin Alleviates Oxidative Stress and Upregulates the Multidrug Resistance Protein 2 in Isoniazid and Rifampicin-Induced Liver Injury in Rats.
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China. xinanwu6511@163.com.
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.|Department of Core laboratory, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Junfang
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Yuhui
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Lili
authors.initials: L
authors.lastname: Xi
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Qin
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Rao
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.|College of Pharmaceutical Science, Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Miao
authors.initials: M
authors.lastname: Han
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Yanrong
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Department of Pharmacy, The First Hospital of Lanzhou University, Lanzhou, 730000, People's Republic of China.
authors.forename: Xin'an
authors.initials: X
authors.lastname: Wu
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B / Q000819:agonists* / Q000378:metabolism; D000410:Alanine Transaminase / Q000097:blood; D000818:Animals; D000995:Antitubercular Agents / Q000633:toxicity; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D056486:Chemical and Drug Induced Liver Injury / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D005978:Glutathione / Q000378:metabolism; D005979:Glutathione Peroxidase / Q000378:metabolism; D005980:Glutathione Reductase / Q000378:metabolism; D006569:Hesperidin / Q000494:pharmacology*; D007538:Isoniazid / Q000633:toxicity*; D008099:Liver / Q000187:drug effects / Q000378:metabolism / Q000473:pathology; D008297:Male; D018384:Oxidative Stress; D020011:Protective Agents / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D012293:Rifampin / Q000633:toxicity*; D015854:Up-Regulation
chemical_list: D018435:ATP Binding Cassette Transporter, Subfamily B; D000995:Antitubercular Agents; D020011:Protective Agents; C095122:multidrug resistance protein 3; D006569:Hesperidin; D005979:Glutathione Peroxidase; D005980:Glutathione Reductase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D005978:Glutathione; D001663:Bilirubin; D007538:Isoniazid; D012293:Rifampin
keywords: Hesperidin; Isoniazid; Multidrug resistance proteins; Oxidative stress; Rifampicin