title: Duct Ectasia and Periductal Mastitis in Indian Women.
abstract: There is very little awareness of the general physicians and surgeons about the benign breast conditions such as duct ectasia (DE) and periductal mastitis (PDM) causing nipple discharge. Not only that these benign breast diseases ring a false alarm of cancer, they are also the second most common cause of benign breast diseases. The objective was to study the clinical and microbiological profiles of duct ectasia and periductal mastitis in Indian women for better understanding of the disease process, in order to be able to treat them well. Forty-one consecutive patients presenting to the Surgical Out-Patient Department with non-bloody nipple discharge with clinical and radiological features suggestive of DE or PDM were included. Microbial culture and cytopathological study of the nipple discharge were done. Histopathological studies and culture of the ductal tissue taken intraoperatively were carried out. There is no significant difference in the age distribution among women with DE and PDM. Smoking is not associated with DE and PDM of Indian patients in contrast to the Western literature evidence. Infective etiology was present in nearly 46 % of the patients in the study population more so in the periductal mastitis cases. The most common isolated pathogens were Staphylococcus aureus and Staphylococcus epidermidis, unlike in Western population where nearly 50 % were anaerobes. Since the isolated organisms were resistant to the routinely used antibiotics in high proportion of cases, culture and sensitivity should be done in all possible cases for appropriately treating the subareolar sepsis before proceeding with the definitive treatment in the form of duct excision.
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India ; Door No. D'3, Second Floor, Queens' Apartment, Banyan Beach Resort Compound, Old pattinam Pathai, Kottakuppam, Pondicherry, 605104 India.
authors.forename: Kirithiga
authors.initials: K
authors.lastname: Ramalingam
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Anurag
authors.initials: A
authors.lastname: Srivastava
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Seenu
authors.initials: S
authors.lastname: Vuthaluru
authors.affiliation: Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Anita
authors.initials: A
authors.lastname: Dhar
authors.affiliation: Microbiology Department, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Rama
authors.initials: R
authors.lastname: Chaudhry
keywords: Benign breast disease; Culture of nipple discharge; Duct ectasia; Duct ectasia in Indian women; Mammary duct excision; Management of periductal mastitis/duct ectasia; Mastitis in Indian women; Nipple discharge; Periductal mastitis