title: Should we interpret the results of 'two-step' glucose screening again according to the obstetric outcomes?
abstract: We aimed to re-evaluate the 'two-step' antenatal glucose screening programme in relation to maternal and foetal outcomes in pregnant women screened for gestational diabetes mellitus and to compare maternal and foetal outcomes between different groups divided according to glucose tolerance test results. Two-thousand four-hundred and two pregnant women attending for antenatal care were recruited retrospectively for the study. Mean birthweight for pregnancies with single-value abnormality (SVA) in 100-g oral glucose tolerance test (OGTT) was significantly higher than the control group [3420 ± 378 vs. 3294 ± 444]. We found a significantly higher rate of macrosomia in the subgroup of 50-g glucose challenge test (GCT) between 130 and 140 mg/dl [9.7% vs. 4.8%]. Pregnant women whose 50-g GCT results are between 130 and 140 mg/dl or who have SVA in 100-g OGTT not only have gestational diabetes, but are also at increased risk for diabetic complications.
authors.affiliation: a Department of Obstetrics and Gynecology , Kecioren Education and Research Hospital , Ankara , Turkey and.
authors.forename: Mehmet Murat
authors.initials: MM
authors.lastname: Seval
authors.affiliation: a Department of Obstetrics and Gynecology , Kecioren Education and Research Hospital , Ankara , Turkey and.
authors.forename: Sabri
authors.initials: S
authors.lastname: Cavkaytar
authors.affiliation: a Department of Obstetrics and Gynecology , Kecioren Education and Research Hospital , Ankara , Turkey and.
authors.forename: Zeliha
authors.initials: Z
authors.lastname: Atak
authors.affiliation: b Department of Clinical Biochemistry , Kecioren Education and Research Hospital , Ankara , Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Cagman
mesh_terms: D000328:Adult; D001724:Birth Weight; D001786:Blood Glucose / Q000032:analysis*; D016640:Diabetes, Gestational / Q000175:diagnosis*; D005260:Female; D005320:Fetal Macrosomia / Q000209:etiology; D005865:Gestational Age; D005951:Glucose Tolerance Test / Q000706:statistics & numerical data*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011256:Pregnancy Outcome; D011295:Prenatal Care / Q000706:statistics & numerical data; D012189:Retrospective Studies
chemical_list: D001786:Blood Glucose
keywords: Gestastional diabetes mellitus; diabetic complications; glucose screening; macrosomia