title: Fluorescence detection of telomerase activity in high concentration of cell lysates based on strand-displacement mediated recycling.
abstract: Based on a template of the telomere elongation reaction of a telomerase substrate primer in the presence of telomerase, the strand-displacement process was used to prepare a fluorescence signal nanoprobe. An amplified fluorescence detection of telomerase activity in cancer cells is described in this manuscript.
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P.R. China. dingcaifeng2003@163.com.
authors.forename: Xiaoqian
authors.initials: X
authors.lastname: Li
authors.forename: Wei
authors.initials: W
authors.lastname: Wang
authors.forename: Yaoyao
authors.initials: Y
authors.lastname: Chen
authors.forename: Caifeng
authors.initials: C
authors.lastname: Ding
mesh_terms: D016923:Cell Death; D057075:Enzyme Assays / Q000379:methods*; D005240:Feasibility Studies; D006367:HeLa Cells; D006801:Humans; D013050:Spectrometry, Fluorescence; D019098:Telomerase / Q000378:metabolism*
chemical_list: D019098:Telomerase