title: Synchronous uterine adenocarcinoma and leiomyosarcoma: A rare case report causing a clinical conundrum.
abstract: BACKGROUND
  Synchronous gynecologic primary cancers are uncommon. When present, the most frequent malignancies consist of endometrial and ovarian carcinomas. Here we report an exceedingly rare case of concurrent uterine adenocarcinoma and leiomyosarcoma.
  
  
  METHODS
  A 60 year-old female presented with four years of postmenopausal bleeding. An endometrial sampling showed grade 2 endometrioid adenocarcinoma. She proceeded with hysterectomy that contained an anterior endometrial mass and a posterior myometrial mass. The final pathology demonstrated concurrent uterine adenocarcinoma and leiomyosarcoma.
  
  
  CONCLUSIONS
  To the best of our knowledge, this is the third reported case of simultaneous uterine adenocarcinoma and leiomyosarcoma. As this presentation is infrequent with limited literature, this caused a clinical management conundrum. Unfortunately, the follow-up PET scan suggested possible recurrence or metastasis three months after the surgery.
  
  
  CONCLUSIONS
  Simultaneous uterine adenocarcinoma and leiomyosarcoma is an exceptionally rare event. As the experience is limited, a multidisciplinary approach in managing these patients may be the best option currently available.
authors.affiliation: Department of Obstetrics and Gynecology, University of California, Davis Medical Center, Sacramento, CA, United States. Electronic address: kkcrean@ucdavis.edu.
authors.forename: Katie K
authors.initials: KK
authors.lastname: Crean
authors.affiliation: Department of Pathology and Laboratory Medicine, University of California, Davis Medical Center, Sacramento, CA, United States.
authors.forename: Eric C
authors.initials: EC
authors.lastname: Huang
authors.affiliation: Department of Obstetrics and Gynecology, University of California, Davis Medical Center, Sacramento, CA, United States.
authors.forename: Edwin A
authors.initials: EA
authors.lastname: Alvarez
keywords: Adenocarcinoma; Concurrent; Leiomyosarcoma; Synchronous; Uterus