title: [Disease burden of colorectal cancer in Jinchang cohort].
abstract: OBJECTIVE
  To evaluate the disease burden of colorectal cancer in Jinchang cohort, and provide evidence for preventing colorectal cancer and reducing the disease burden of colorectal cancer in the cohort.
  
  
  METHODS
  The colorectal cancer mortality data from 2001 to 2013 and the medical records of colorectal cancer patients from 2001 to 2010 were collected for this retrospective cohort study. The colorectal cancer disease burden was described by using mortality rate, standardized mortality rate, medical expenditure, potential years of life lost (PYLL), average potential years of life lost (APYLL), working potential years of life lost (WPYLL), and average working potential years of life lost (AWPYLL). The development trend in disease burden of colorectal cancer was analyzed by using Spearman correlation and the average growth rate.
  
  
  RESULTS
  The crude mortality rate of colorectal cancer from 2001 to 2013 was 9.53/100,000 with the average annual growth rate of 12.89%. The PYLL, APYLL, WPYLL and AWPYLL of colorectal cancer were 485.00 person-years, 9.15 years, 253.00 person-years, and 4.77 years, respectively. The direct medical expenditure due to colorectal cancer was 7064.38 Yuan per case and 408.43 Yuan per day. There was no increasing trend in the direct medical expenditure due to colorectal cancer.
  
  
  CONCLUSIONS
  Colorectal cancer mortolity rate was on the rise and it caused heavy disease burden in Jinchang cohort.
authors.affiliation: Department of Cancer Prevention, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Chang
authors.affiliation: Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China.
authors.forename: Yana
authors.initials: Y
authors.lastname: Bai
authors.affiliation: Workers'Hospital of Jinchuan Group Company Limited, Jinchang 737100, China.
authors.forename: Hongquan
authors.initials: H
authors.lastname: Pu
authors.affiliation: Program Office for Cancer Screening in Urban China,Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Ni
authors.initials: N
authors.lastname: Li
authors.affiliation: School of Basic Medical Sciences, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Cheng
authors.affiliation: Workers'Hospital of Jinchuan Group Company Limited, Jinchang 737100, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Li
authors.affiliation: Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China.
authors.forename: Zhidong
authors.initials: Z
authors.lastname: Xie
authors.affiliation: Workers'Hospital of Jinchuan Group Company Limited, Jinchang 737100, China.
authors.forename: Fuxin
authors.initials: F
authors.lastname: Li
authors.affiliation: Institute of Epidemiology and Biostatistics, School of Public Health, Center for Cancer Prevention and Control, Lanzhou University, Lanzhou 730000, China.
authors.forename: Xiaobin
authors.initials: X
authors.lastname: Hu
authors.affiliation: Workers'Hospital of Jinchuan Group Company Limited, Jinchang 737100, China.
authors.forename: Jinbing
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Program Office for Cancer Screening in Urban China,Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Jie
authors.initials: J
authors.lastname: He
authors.affiliation: Program Office for Cancer Screening in Urban China,Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.
authors.forename: Min
authors.initials: M
authors.lastname: Dai
mesh_terms: D002681:China / Q000453:epidemiology; D015179:Colorectal Neoplasms / Q000191:economics* / Q000401:mortality*; D017281:Cost of Illness; D005102:Health Expenditures / Q000706:statistics & numerical data; D006801:Humans; D012189:Retrospective Studies