title: [Immune and genetic changes in workers exposed to industrial noise and dust].
abstract: Comparative analysis covered immune genetic parameters in nonferrous metallurgy workers. The authors demonstrated differences in immune genetic profile between male and female workers, under exposure to combination of occupational hazards: noise and dust. Analysis of gene polymorphism revealed predominant disorders in the female workers, concerning criterion of prevalence for minor allele of genes in 1 and 2 phases of detoxication, neuro-endocrine regulation, lipid and energy metabolism, genes of immune regulation and apoptosis.
authors.forename: O V
authors.initials: OV
authors.lastname: Dolgikh
authors.forename: A M
authors.initials: AM
authors.lastname: Krivtsov
authors.forename: K G
authors.initials: KG
authors.lastname: Starkova
authors.forename: O A
authors.initials: OA
authors.lastname: Boubnova
authors.forename: D G
authors.initials: DG
authors.lastname: Dianova
authors.forename: N A
authors.initials: NA
authors.lastname: Vdovina
authors.forename: V M
authors.initials: VM
authors.lastname: Uhabov
mesh_terms: D000328:Adult; D000395:Air Pollutants, Occupational / Q000009:adverse effects* / Q000032:analysis; D016022:Case-Control Studies; D004391:Dust / Q000032:analysis*; D005260:Female; D005838:Genotype; D006801:Humans; D055633:Immune System Phenomena / Q000187:drug effects* / Q000235:genetics; D007111:Immunity, Cellular / Q000187:drug effects / Q000235:genetics; D056724:Immunity, Humoral / Q000187:drug effects / Q000235:genetics; D008658:Inactivation, Metabolic / Q000187:drug effects / Q000235:genetics; D008297:Male; D008669:Metallurgy; D009623:Noise, Occupational / Q000009:adverse effects*; D020641:Polymorphism, Single Nucleotide / Q000187:drug effects* / Q000276:immunology; D012426:Russia; D012737:Sex Factors
chemical_list: D000395:Air Pollutants, Occupational; D004391:Dust