title: Reconstruction with β-Tricalcium Phosphate for Giant Cell Tumor of Bone around the Knee.
abstract: Giant cell tumor of bone is a locally aggressive metaphyseal lesion extending to the epiphysis, mostly occurring around the knee joint. Reconstruction to preserve the joint is difficult when there is little subarticular bone. Four such cases with a giant cell tumor of bone around the knee joint were treated by curettage and reconstruction using β-tricalcium phosphate (β-TCP). Block-shaped β-TCP with high mechanical strength (hard-type β-TCP) was implanted into the cavity, while standard β-TCP particles were put into the subarticular space. Exercise to promote improved range of motion was performed after the operation. The hard-type β-TCP is mechanically stronger than cancellous bone. Therefore, weight bearing can start around 3 months postoperatively when bone has been incorporated into the subarticular area but before complete bone incorporation into the lesion. This reconstructive procedure also provides excellent knee function.
authors.affiliation: Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Sakamoto
mesh_terms: D000328:Adult; D001672:Biocompatible Materials; D001859:Bone Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D002130:Calcium Phosphates; D005260:Female; D005269:Femur; D018212:Giant Cell Tumor of Bone / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D008297:Male; D016059:Range of Motion, Articular; D013977:Tibia
chemical_list: D001672:Biocompatible Materials; D002130:Calcium Phosphates; C485817:beta-tricalcium phosphate