title: Guideline-Concordant Versus Discordant Antimicrobial Therapy in Patients With Community-Onset Complicated Intra-abdominal Infections.
abstract: Overall IDSA/SIS intra-abdominal infection guideline compliance was not associated with improved outcomes; however, there was a longer time to active therapy (P=.024) and higher mortality (P=.077) if empiric therapy was too narrow per guidelines. These findings support the need for the implementation of customized institutional guidelines adapted from the IDSA/SIS guidelines. Infect Control Hosp Epidemiol 2016;37:855-858.
authors.affiliation: 1Veterans' Affairs Medical Center,Patient Care Services,Ann Arbor,Michigan.
authors.forename: Lori L
authors.initials: LL
authors.lastname: Huang
authors.affiliation: 3University of Nebraska Medical Center,College of Medicine,Omaha,Nebraska.
authors.forename: Trevor C
authors.initials: TC
authors.lastname: Van Schooneveld
authors.affiliation: 3University of Nebraska Medical Center,College of Medicine,Omaha,Nebraska.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Huang
authors.affiliation: 2University of Nebraska Medical Center,College of Pharmacy,Omaha,Nebraska.
authors.forename: Keith M
authors.initials: KM
authors.lastname: Olsen
authors.affiliation: 3University of Nebraska Medical Center,College of Medicine,Omaha,Nebraska.
authors.forename: Mark E
authors.initials: ME
authors.lastname: Rupp
authors.affiliation: 2University of Nebraska Medical Center,College of Pharmacy,Omaha,Nebraska.
authors.forename: Alan E
authors.initials: AE
authors.lastname: Gross
mesh_terms: D000328:Adult; D000368:Aged; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology / Q000401:mortality; D003428:Cross Infection / Q000188:drug therapy / Q000401:mortality; D019983:Guideline Adherence / Q000706:statistics & numerical data*; D006801:Humans; D059413:Intraabdominal Infections / Q000188:drug therapy* / Q000382:microbiology / Q000401:mortality; D008875:Middle Aged; D017410:Practice Guidelines as Topic; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000890:Anti-Infective Agents