title: Five Years' Evaluation of the BD ProbeTec System for the Direct Molecular Detection of Mycobacterium tuberculosis Complex in Respiratory and Nonrespiratory Clinical Samples.
abstract: In this study, Mycobacterium tuberculosis complex was detected by BD ProbeTec ET system in 4716 respiratory and 167 nonrespiratory samples [mostly (98%) smear negative). Sensitivity, specificity, positive and negative predictive values were 81.8%, 98.3, 85.1 and 97.9 for respiratory and 100%, 96.2, 64.7 and 100, for nonrespiratory samples, respectively. Among 149 (3.1%) ProbeTec DTB positive and culture negative samples, 72 (65 respiratory and seven nonrespiratory) (48.3%) were recovered from the patients who were evaluated as having TB infection. The system has been found as useful in early diagnosis of tuberculosis infection in association with the clinical, radiological and histopathological findings.
authors.forename: Can
authors.initials: C
authors.lastname: Bicmen
authors.forename: Onur
authors.initials: O
authors.lastname: Karaman
authors.forename: Ayriz T
authors.initials: AT
authors.lastname: Gunduz
authors.forename: Onur F
authors.initials: OF
authors.lastname: Erer
authors.forename: Meral
authors.initials: M
authors.lastname: Coskun
authors.forename: Osman
authors.initials: O
authors.lastname: Kaftan
authors.forename: Mahmut M
authors.initials: MM
authors.lastname: Demirel
authors.forename: Gunes
authors.initials: G
authors.lastname: Senol
authors.forename: Tulay
authors.initials: T
authors.lastname: Akarca
authors.forename: Sevket
authors.initials: S
authors.lastname: Dereli
authors.forename: Ayse
authors.initials: A
authors.lastname: Ozsoz
mesh_terms: D015373:Bacterial Typing Techniques; D001431:Bacteriological Techniques / Q000295:instrumentation* / Q000379:methods; D001826:Body Fluids / Q000382:microbiology; D002555:Cerebrospinal Fluid / Q000382:microbiology; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D010996:Pleural Effusion / Q000382:microbiology; D011237:Predictive Value of Tests; D011933:Reagent Kits, Diagnostic; D012680:Sensitivity and Specificity; D013183:Sputum / Q000382:microbiology*; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology; D014556:Urine / Q000382:microbiology
chemical_list: D011933:Reagent Kits, Diagnostic