title: Profile of microRNA in Blood Plasma of Healthy Humans.
abstract: Analysis of the plasma microRNA profile can be used for the diagnosis of various pathological and physiological conditions. Complete microRNA microprofiling is an extremely important task. Here we used microarray analysis allowing measurement of the expression of 2500 microRNA (MirBase, version 20). About 10% known microRNA were found in the plasma. Most of the detected microRNA (69 microRNA; ~30%) were encoded by mirtrons.
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia. mshkurnikov@gmail.com.|Bioclinicum Research and Engineering Center, Moscow, Russia. mshkurnikov@gmail.com.
authors.forename: M Yu
authors.initials: MY
authors.lastname: Skurnikov
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.|V. A. Engelhard Institute of Molecular Biology, Russian Academy of Sciences, Moscow, Russia.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Makarova
authors.affiliation: Bioclinicum Research and Engineering Center, Moscow, Russia.
authors.forename: E N
authors.initials: EN
authors.lastname: Knyazev
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: K A
authors.initials: KA
authors.lastname: Fomicheva
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: K M
authors.initials: KM
authors.lastname: Nyushko
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: E K
authors.initials: EK
authors.lastname: Saribekyan
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: B Ya
authors.initials: BY
authors.lastname: Alekseev
authors.affiliation: P. A. Gertsen Moscow Research Oncological Institute, Branch of the Medical Research Radiological Center, Ministry of Health of the Russian Federation, Moscow, Russia.
authors.forename: A D
authors.initials: AD
authors.lastname: Kaprin
mesh_terms: D000328:Adult; D005819:Genetic Markers; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D035683:MicroRNAs / Q000097:blood*; D009369:Neoplasms / Q000097:blood* / Q000175:diagnosis* / Q000235:genetics; D020411:Oligonucleotide Array Sequence Analysis
chemical_list: D005819:Genetic Markers; D035683:MicroRNAs
keywords: blood plasma; healthy volunteers; microRNA