title: Rethinking preventive post-discharge intervention programmes for very preterm infants and their parents.
abstract: Post-discharge preventive intervention programmes with involvement of the parent may support the resilience and developmental outcomes of infants born very preterm. Randomized controlled trials of home-based family-centred intervention programmes in very preterm infants that aimed to improve cognitive outcome, at least at age two, were selected and updated on the basis of a recent systematic review to compare their content and effect over time to form the basis of a narrative review. Six programmes were included in this narrative review. Four of the six programmes led to improved child cognitive and/or motor development. Two programmes, which focused primarily on responsive parenting and development, demonstrated improved cognitive outcome up till 5 years after completion of the programme. The programmes that also focused on maternal anxiety remediation led to improved maternal mental well-being, along with improved child behaviour, in one study - even at 3 years after completion of the programme. The magnitude of the effects was modest. Family-centred preventive intervention programmes that aim at improvement of child development should be continued after discharge home to improve the preterm child's resilience. Programmes may be most effective when they support the evolvement of a responsive parent-infant relationship over time, as well as the parent's well-being.
authors.affiliation: Department of Neonatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Aleid G
authors.initials: AG
authors.lastname: van Wassenaer-Leemhuis
authors.affiliation: Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Martine
authors.initials: M
authors.lastname: Jeukens-Visser
authors.affiliation: Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Janeline W P
authors.initials: JW
authors.lastname: van Hus
authors.affiliation: Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Dominique
authors.initials: D
authors.lastname: Meijssen
authors.affiliation: Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Marie-Jeanne
authors.initials: MJ
authors.lastname: Wolf
authors.affiliation: Department of Neonatology, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Joke H
authors.initials: JH
authors.lastname: Kok
authors.affiliation: Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Frans
authors.initials: F
authors.lastname: Nollet
authors.affiliation: Department of Rehabilitation, Academic Medical Centre, University of Amsterdam, Amsterdam, the Netherlands.
authors.forename: Karen
authors.initials: K
authors.lastname: Koldewijn
mesh_terms: D000328:Adult; D002657:Child Development / Q000502:physiology*; D002675:Child, Preschool; D005196:Family Therapy / Q000379:methods*; D006801:Humans; D007223:Infant; D062071:Infant, Extremely Premature / Q000502:physiology*; D007231:Infant, Newborn; D010287:Parent-Child Relations; D016487:Parenting / Q000523:psychology*; D011322:Primary Prevention / Q000379:methods*