title: [FEATURES BONE METABOLISM IN ADOLESCENTS LIVING IN KAZAKHSTAN (ON THE EXAMPLE AKTOBE)].
abstract: The purpose of this work is to study by densitometry the bone mineral density (BMD) in Kazakhstan adolescents of Aktobe and biological markers of the bone metabolism. By obtained data revealed the presence of osteopenia among apparently healthy Kazakhstan adolescents in 72% of cases. Indicators of bone mineral density in adolescents two ethnic groups (Kazakhs and Russian) were unremarkable. Sexual features of the BMD concluded that the sign of osteoporosis was 1.5 times higher among boys than girls. Remodeling of bone tissue in the examined pupils was due to the markers of osteosynthesis and osteoresorption respectively PINP and ß-CrossLaps with their strong correlation (r=0.8) in normal and reduced BMD. Reduced BMD in Kazakhstan adolescents is reflected in increased value of the marker ß-CrossLaps and humoral regulator of PTH, responsible for osteoresorbtion of the overall process of the bone remodeling.
authors.affiliation: Marat Ospanov West Kazakhstan State Medical University, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: R
authors.initials: R
authors.lastname: Nurgalieva
authors.affiliation: Marat Ospanov West Kazakhstan State Medical University, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: A
authors.initials: A
authors.lastname: Amanzholkyzy
authors.affiliation: Marat Ospanov West Kazakhstan State Medical University, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: A
authors.initials: A
authors.lastname: Kaldybaeva
authors.affiliation: Marat Ospanov West Kazakhstan State Medical University, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: A
authors.initials: A
authors.lastname: Dosimov
authors.affiliation: Marat Ospanov West Kazakhstan State Medical University, Aktobe, Kazakhstan; Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: E
authors.initials: E
authors.lastname: Stankevichus
mesh_terms: D000293:Adolescent; D015415:Biomarkers / Q000097:blood / Q000652:urine; D015519:Bone Density; D016723:Bone Remodeling; D001842:Bone and Bones / Q000378:metabolism*; D005260:Female; D006801:Humans; D008297:Male; D010024:Osteoporosis / Q000378:metabolism / Q000503:physiopathology; D012737:Sex Factors
chemical_list: D015415:Biomarkers