title: Design of Multiple Logic Gates Based on Chemically Triggered Fluorescence Switching of Functionalized Polyethylenimine.
abstract: In this study, two new functionalized polyethylenimine (PEI), PEIR and PEIQ, have been synthesized by covalently conjugating rhodamine 6G (R6G) or 8-chloroacetyl-aminoquinoline (CAAQ) and have been investigated for their sensing capabilities toward metal ions and anions basing on fluorescence on-off and off-on mechanisms. When triggered by protons, metal ions, or anions, functionalized PEIs can behave as a fluorescence switch, leading to a multiaddressable system. Inspired by these results, functionalized PEI-based logic systems capable of performing elementary logic operations (YES, NOT, NOR, and INHIBIT) and integrative logic operations (OR + INHIBIT) have been constructed by observing the change in the fluorescence with varying the chemical inputs such as protons, metal ions, and anions. Due to its characteristics, such as high sensitivity and fast response, developing functionalized PEI as a new material to perform logic operations may pave a new avenue to construct the next generation of molecular devices with better applicability for biomedical research.
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Pan
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Yupeng
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Zhihua
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Junying
authors.initials: J
authors.lastname: Chen
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Mengfei
authors.initials: M
authors.lastname: Hou
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Zhanpeng
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Institute of Chinese Medical Sciences, University of Macau , Macau, China.
authors.forename: Cheuk-Wing
authors.initials: CW
authors.lastname: Li
authors.affiliation: Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University , Guangzhou, 510275 China.
authors.forename: Changqing
authors.initials: C
authors.lastname: Yi
mesh_terms: D000634:Aminoquinolines / Q000737:chemistry; D039301:Computers, Molecular; D005453:Fluorescence; D007477:Ions / Q000737:chemistry; D008670:Metals / Q000737:chemistry; D011094:Polyethyleneimine / Q000138:chemical synthesis / Q000737:chemistry*; D011522:Protons; D012235:Rhodamines / Q000737:chemistry
chemical_list: D000634:Aminoquinolines; D007477:Ions; D008670:Metals; D011522:Protons; D012235:Rhodamines; C026188:rhodamine 6G; D011094:Polyethyleneimine
keywords: 8-chloroacetyl-aminoquinoline; fluorescence; functionalized polyethylenimine; logic gates; rhodamine 6G