title: [Drug-induced dementia].
abstract: Many drugs have been reported to induce not only delirium but also cognitive impairment. Some types of drugs are reported to induce dementia, and prolonged hypotension or hypoglycemia induced by overuse of antihypertensive drugs or oral antidiabetic drugs could result in dementia. Recently, taking multiple drugs with anticholinergic activity are reported to cause cognitive decline and anticholinergic burden should be avoided especially in patients with dementia. Drug-induced dementia can be prevented by avoiding polypharmacy and adhering to the saying 'start low and go slow' . Early diagnosis of drug-induced dementia and withdrawal of the offending drug is essential to improve cognitive function.
authors.forename: Taro
authors.initials: T
authors.lastname: Kojima
authors.forename: Masahiro
authors.initials: M
authors.lastname: Akishita
mesh_terms: D018680:Cholinergic Antagonists / Q000009:adverse effects; D003704:Dementia / Q000139:chemically induced*; D006801:Humans; D000067561:Potentially Inappropriate Medication List
chemical_list: D018680:Cholinergic Antagonists