title: Albumin-bilirubin score for predicting the in-hospital mortality of acute upper gastrointestinal bleeding in liver cirrhosis: A retrospective study.
abstract: OBJECTIVE
  The albumin-bilirubin (ALBI) score is a new model for assessing the severity of liver dysfunction. In the present study, we aimed to retrospectively compare the performance of ALBI with Child-Pugh and the model for end-stage liver disease (MELD) scores for predicting the in-hospital mortality of acute gastrointestinal bleeding (AUGIB) in liver cirrhosis.
  
  
  METHODS
  All cirrhotic patients with AUGIB were eligible, provided they had the data needed to determine the ALBI score. Areas under the receiving-operator characteristics curve (AUC) are reported.
  
  
  RESULTS
  Overall, 631 patients were included. In all the included patients, the AUC of the ALBI, Child-Pugh, and MELD scores were 0.808, 0.785 (p=0.5831), and 0.787 (p=0.7033), respectively. In patients with only hepatitis B virus-related liver cirrhosis, the AUC of the ALBI, Child-Pugh, and MELD scores were 0.865, 0.836 (p=0.6064), and 0.818 (p=0.6399), respectively. In patients with only alcohol-related liver cirrhosis, the AUC of the ALBI, Child-Pugh, and MELD scores were 0.869, 0.860 (p=0.9003), and 0.801 (p=0.5548), respectively. In patients treated with endoscopic therapy for AUGIB, the AUC of the ALBI, Child-Pugh, and MELD scores were 0.873, 0.884 (p=0.7898), and 0.834 (p=0.5531), respectively.
  
  
  CONCLUSIONS
  The prognostic performance of the ALBI score was comparable with that of the Child-Pugh and MELD scores for predicting the in-hospital mortality of AUGIB in liver cirrhosis.
authors.affiliation: Liver Cirrhosis Study Group, Department of Gastroenterology, General Hospital of Shenyang Military Area, No. 83 Wenhua Road, Shenyang, China. guo_xiao_zhong@126.com.
authors.forename: Deli
authors.initials: D
authors.lastname: Zou
authors.forename: Xingshun
authors.initials: X
authors.lastname: Qi
authors.forename: Cuihong
authors.initials: C
authors.lastname: Zhu
authors.forename: Zheng
authors.initials: Z
authors.lastname: Ning
authors.forename: Feifei
authors.initials: F
authors.lastname: Hou
authors.forename: Jiancheng
authors.initials: J
authors.lastname: Zhao
authors.forename: Ying
authors.initials: Y
authors.lastname: Peng
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Han
authors.initials: H
authors.lastname: Deng
authors.forename: Xiaozhong
authors.initials: X
authors.lastname: Guo
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001663:Bilirubin / Q000097:blood; D002648:Child; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000401:mortality*; D017052:Hospital Mortality; D006801:Humans; D008103:Liver Cirrhosis / Q000097:blood* / Q000150:complications / Q000401:mortality; D008111:Liver Function Tests / Q000379:methods; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D012709:Serum Albumin / Q000032:analysis; D012720:Severity of Illness Index; D055815:Young Adult
chemical_list: D012709:Serum Albumin; D001663:Bilirubin