title: New Finding in Vernal Keratoconjunctivitis: Splendore-Hoeppli Phenomenon.
abstract: OBJECTIVE
  To report 2 cases of Splendore-Hoeppli phenomenon, a rare histopathologic observation, as a late clinical finding in vernal keratoconjunctivitis (VKC).
  
  
  METHODS
  We report the cases of 2 young women with subconjunctival nodules as a manifestation of Splendore-Hoeppli phenomenon with a history of severe VKC.
  
  
  RESULTS
  After eliminating other conditions causing such a reaction, both patients were treated using frequent topical corticosteroid, plus topical cyclosporine 2% in one of patient. Complete resolution was observed in both patients.
  
  
  CONCLUSIONS
  The Splendore-Hoeppli phenomenon could be a part of VKC manifestations.
authors.affiliation: Eye Research Center, Ocular Trauma and Emergency Unit, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Soleimani
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Tabatabaei
authors.forename: Reza
authors.initials: R
authors.lastname: Mirshahi
authors.forename: Zohreh
authors.initials: Z
authors.lastname: Nozarian
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Jabbarvand Behrbouz
mesh_terms: D000328:Adult; D001623:Betamethasone / Q000627:therapeutic use; D003233:Conjunctivitis, Allergic / Q000175:diagnosis* / Q000188:drug therapy; D016572:Cyclosporine / Q000627:therapeutic use; D003594:Cytoplasmic Granules / Q000473:pathology; D004803:Eosinophilic Granuloma / Q000175:diagnosis* / Q000188:drug therapy; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents; D016572:Cyclosporine; D001623:Betamethasone