title: Plasma engineered surfaces for orthopedic devices.
abstract: Atmospheric pressure plasma was used to graft various biocompatible polymers to the surface of ultra-high molecular weight polyethylene (UHMWPE). Polymers used as grafts in this study were poly(2-hydroxyethylmethacrylate) (PHEMA) and polyethylene glycol (PEG). A significant decrease in contact angle was noted for grafted surfaces, indicating increased hydrophilicity. Surface functionalities were verified using Fourier transform infrared spectroscopy and X-ray photoelectron spectroscopy. The wear properties of the coatings were determined by weight loss under conditions of a random motion pin-on-plate apparatus with the coated polyethylene plaques immersed in DI water. Based on these tests, the grafted surfaces exhibited an improved resistance to wear, compared to UHMWPE. Cell viability studies were used to confirm that the plasma treatment had no negative effects on the surface bio-toxicity. Based on the results, it is anticipated that the incorporation of these biocompatible polymer-grafted UHMWPE surfaces in metal-on-plastic orthopedic implants should improve their performance and longevity.
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Susan
authors.initials: S
authors.lastname: Farhat
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Mary
authors.initials: M
authors.lastname: Gilliam
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Cheryl
authors.initials: C
authors.lastname: Samaniego
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Nate
authors.initials: N
authors.lastname: Dwarshuis
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Julia
authors.initials: J
authors.lastname: Carson
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Peterson
authors.affiliation: a Department of Chemistry, Biochemistry, Chemical Engineering, and Applied Biology , Kettering University , Flint , MI , USA.
authors.forename: Ali
authors.initials: A
authors.lastname: Zand
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry* / Q000494:pharmacology*; D002470:Cell Survival / Q000187:drug effects; D004738:Engineering; D008422:Materials Testing; D051379:Mice; D009985:Orthopedics; D058626:Plasma Gases / Q000737:chemistry*; D011092:Polyethylene Glycols / Q000737:chemistry; D011095:Polyethylenes / Q000737:chemistry; D019736:Prostheses and Implants; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D058626:Plasma Gases; D011095:Polyethylenes; C111601:ultra-high molecular weight polyethylene; D011092:Polyethylene Glycols
keywords: Atmospheric pressure plasma; implants; polymer grafting; wear properties