title: Biomechanical, micro-computed tomographic and immunohistochemical analysis of early osseous integration at titanium implants placed following lateral ridge augmentation using extracted tooth roots.
abstract: OBJECTIVE
  To assess biomechanical, micro-computed tomographic (micro CT) and immunohistochemical characteristics of early osseous integration at titanium implants placed following lateral ridge augmentation using autogenous extracted tooth roots.
  
  
  METHODS
  The roots of healthy maxillary premolars (PM) and retromolar cortical autogenous bone (AB) blocks were used for lateral ridge augmentation at chronic-type defects in the lower quadrants of n = 16 foxhounds. At 12 weeks, titanium implants were inserted and left to heal for another 3 weeks. Osteocalcin (OC) antigen reactivity, removal torque values (RT) and the bone volume per tissue volume (micro CT- BV/TV) along the implants were assessed.
  
  
  RESULTS
  Median OC (PM: 6.71 vs. AB: 2.73%), RT (PM: 61.97 vs. AB: 44.8 Ncm) and BV/TV (PM: 0.34 vs. AB: 0.21) values were comparable in both PM and AB groups.
  
  
  CONCLUSIONS
  PM and AB grafted sites equally supported the early stages of osseointegration.
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.|Department of Orthodontics, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Kathrin
authors.initials: K
authors.lastname: Becker
authors.affiliation: Department of Orthodontics, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Dieter
authors.initials: D
authors.lastname: Drescher
authors.affiliation: Department of Orthodontics, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Ralf
authors.initials: R
authors.lastname: Hönscheid
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Golubovic
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Ilja
authors.initials: I
authors.lastname: Mihatovic
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
mesh_terms: D000540:Alveolar Ridge Augmentation; D000818:Animals; D001696:Biomechanical Phenomena; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D017267:Dental Prosthesis Design; D004285:Dogs; D007150:Immunohistochemistry; D008334:Mandible / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology* / Q000601:surgery; D016348:Osseointegration; D014025:Titanium; D014057:Tomography, X-Ray Computed / Q000379:methods; D014081:Tooth Extraction; D014092:Tooth Root
chemical_list: D015921:Dental Implants; D014025:Titanium
keywords: alveolar ridge augmentation; animal experiment; histological technique; tooth transplantation