title: p85α is an intrinsic regulator of human natural killer cell effector functions.
authors.affiliation: Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Brescia, Italy. Electronic address: vlougarisbs@yahoo.com.
authors.forename: Vassilios
authors.initials: V
authors.lastname: Lougaris
authors.affiliation: Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Ornella
authors.initials: O
authors.lastname: Patrizi
authors.affiliation: Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Manuela
authors.initials: M
authors.lastname: Baronio
authors.affiliation: Department of Molecular and Translational Medicine, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Giovanna
authors.initials: G
authors.lastname: Tabellini
authors.affiliation: Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Tampella
authors.affiliation: Department of Molecular and Translational Medicine, University of Brescia, Spedali Civili di Brescia, Brescia, Italy; Institute for Molecular Medicine A. Nocivelli, Laboratory of Genetic Disorders of Childhood, University of Brescia, Spedali Civili di Brescia, Brescia, Italy; Department of Pathology, Laboratory of Genetic Disorders of Childhood, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Gaetana
authors.initials: G
authors.lastname: Lanzi
authors.affiliation: Pediatric Department, San Paolo Hospital, University of Milan, Milan, Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Salvini
authors.affiliation: Department of Pediatric Oncology and Hematology, ARNAS CIVICO, Palermo, Italy.
authors.forename: Antonino
authors.initials: A
authors.lastname: Trizzino
authors.affiliation: Department of Molecular and Translational Medicine, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Parolini
authors.affiliation: Department of Clinical and Experimental Sciences, Pediatrics Clinic and Institute for Molecular Medicine A. Nocivelli, University of Brescia, Spedali Civili di Brescia, Brescia, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Plebani
mesh_terms: D016022:Case-Control Studies; D015550:Cell Degranulation; D058543:Class Ia Phosphatidylinositol 3-Kinase; D003602:Cytotoxicity, Immunologic; D006801:Humans; D053306:Hyper-IgM Immunodeficiency Syndrome / Q000201:enzymology* / Q000235:genetics / Q000276:immunology*; D007371:Interferon-gamma / Q000096:biosynthesis; D020014:K562 Cells; D007694:Killer Cells, Natural / Q000201:enzymology* / Q000276:immunology*; D009154:Mutation; D019869:Phosphatidylinositol 3-Kinases / Q000235:genetics / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D058543:Class Ia Phosphatidylinositol 3-Kinase; D007371:Interferon-gamma; D019869:Phosphatidylinositol 3-Kinases; C588001:PIK3R1 protein, human