title: Morphological Changes in Degenerative Disc Disease on Magnetic Resonance Imaging: Comparison Between Young and Elderly.
abstract: BACKGROUND
  Morphological changes implicated in low back are complicated by additional age related degenerative changes in spine, which increases with aging. This study aims to compare the morphological MRI findings in young and elderly patients with low back pain and also correlate them with the clinical symptoms.
  
  
  METHODS
  The study was a retrospective hospital record based comparative study carried out in a Teaching Hospital. MRI performed for patients with low back pain during May 2012 to October 2012 were reviewed. The MRI findings were compared between below 60 years and at and above 60 years and were also correlated with symptoms.
  
  
  RESULTS
  A total of 301 MRI met the inclusion criteria out of which 228(75.74%) were young adults and 73(24.25%) were elderly adults. Degenerative changes and disc bulge was more common in elderly. Disc herniations including disc prolapse was more common in young adults. Disc protrusion involving L4-L5 was most common in the elderly while L5-S1 was most common in young adults. Nerve root compression was noted more commonly in the young adults. Radiculopathy was associated with grade III nerve root compression and paramedian disc protrusion in young adults while no such association was noted in elderly. No association of radiculopathy with presence of degenerative changes, spinal stenosis was noted in both groups.
  
  
  CONCLUSIONS
  Degenerative changes are more common in elderly while disc herniations are more common in young adults. Morphologic changes do correlate with symptoms in young adults to some extent while they do not correlate in elderly.
authors.affiliation: Department of Radiology and Imaging, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: O B
authors.initials: OB
authors.lastname: Panta
authors.affiliation: Department of Radiology and Imaging, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: S
authors.initials: S
authors.lastname: Songmen
authors.affiliation: Department of Radiology and Imaging, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: S
authors.initials: S
authors.lastname: Maharjan
authors.affiliation: Department of Radiology and Imaging, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: K
authors.initials: K
authors.lastname: Subedi
authors.affiliation: Department of Radiology and Imaging, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: M A
authors.initials: MA
authors.lastname: Ansari
authors.affiliation: Department of Radiology and Imaging, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal.
authors.forename: R K
authors.initials: RK
authors.lastname: Ghimire
mesh_terms: D000367:Age Factors; D000368:Aged; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D055959:Intervertebral Disc Degeneration / Q000473:pathology*; D017116:Low Back Pain / Q000473:pathology*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009390:Nepal; D012189:Retrospective Studies
keywords: Degenerative disc disease; elderly; low back pain; magnetic resonance imaging; young adults.