title: Eosinophilic Granuloma of the Mandible: Is a Conservative Treatment Sufficient for Local Disease Control?
abstract: Eosinophilic granuloma is the most benign and common form of the Langerhans cell histiocytosis, a rare proliferative disease that can affect single or multiple organs. In the quite common head and neck manifestation these lesions can be confused in the beginning, with other bone diseases such as odontogenic cysts, periodontal disease, or malignancies. Treatment varies depending on the size, number, localization of the lesions, and patient's general conditions. The authors describe here a patient of a single lesion of eosinophilic granuloma localized in the posterior mandible region treated with a very conservative surgical approach in a patient with poor socio-economic conditions. The authors performed teeth extractions, an excisional biopsy and open curettage and after a follow-up of 24 months without partial mandible resection and reconstruction time the lesion had healed. The clinical situation confirmed that, in carefully selective patients, a conservative approach could be a useful therapeutic opportunity.
authors.affiliation: Division of Maxillofacial Surgery, Head and Neck Department, San Giovanni Battista Hospital, University of Turin, Turin, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Fiorini
authors.forename: Cesare
authors.initials: C
authors.lastname: Gallesio
authors.forename: Valentina
authors.initials: V
authors.lastname: Longoni
authors.forename: Guglielmo
authors.initials: G
authors.lastname: Ramieri
mesh_terms: D000328:Adult; D001706:Biopsy; D000072700:Conservative Treatment / Q000379:methods*; D003657:Decision Making; D004803:Eosinophilic Granuloma / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D008297:Male; D008334:Mandible / Q000000981:diagnostic imaging*; D008336:Mandibular Diseases / Q000175:diagnosis / Q000628:therapy*; D049268:Positron-Emission Tomography; D011862:Radiography, Panoramic