title: Analysis of the Optical Quality of Spherical and Aspheric Intraocular Lenses in Simulated Nanophthalmic Eyes.
abstract: OBJECTIVE
  To analyze the optical performance of different implant strategies in simulated nanophthalmic eyes.
  
  
  METHODS
  An optical design software was used. Analysis included eye models that required 30.00, 45.00, and 60.00 diopters (D) intraocular lenses (IOLs) to achieve emmetropia. Spherical and aspheric IOLs were designed. They were tested either with a single implant setting S or by splitting the power into two lenses. Setting P1 had an even split of the power between the lenses and setting P2 had an uneven power split with one-third of the power in the anterior lens and two-thirds in the posterior IOL. The area under the modulation transfer function (MTF) curve was calculated and spherical aberration was recorded in each setting.
  
  
  RESULTS
  Setting S had the worst optical performance in the spherical group and the best performance in the aspheric group. A statistically significant difference was found between setting S and the piggyback options (settings P1 and P2) in all analyzed variables for the spherical and aspheric groups for the 45.00 and 60.00 D IOL requirement. No statistically significant difference was found between the piggyback settings.
  
  
  CONCLUSIONS
  Single aspheric IOLs had better optical performance than piggybacking lower-power aspheric IOLs. In the spherical lenses group, the results were the opposite, with the piggyback options having higher optical quality than the single IOL. MTF shows that single aspheric lenses provide the highest contrast sensitivity among all of the analyzed settings.
authors.forename: Bruno Lovaglio Cançado
authors.initials: BL
authors.lastname: Trindade
authors.forename: Felipe Tayer
authors.initials: FT
authors.lastname: Amaral
authors.forename: Davies William
authors.initials: DW
authors.lastname: de Lima Monteiro
mesh_terms: D058452:Axial Length, Eye / Q000473:pathology; D002386:Cataract / Q000150:complications*; D015350:Contrast Sensitivity / Q000502:physiology; D006801:Humans; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008850:Microphthalmos / Q000150:complications*; D008962:Models, Theoretical; D055095:Optics and Photonics; D018918:Phacoemulsification; D011474:Prosthesis Design; D014785:Vision, Ocular / Q000502:physiology