title: Solid-phase synthesis of Rhodamine-110 fluorogenic substrates and their application in forensic analysis.
abstract: A novel synthetic route for the rapid and efficient preparation of fluorogenic substrates utilizing Rhodamine-110 or similar fluorophores is reported. Applicability of the synthesized peptide substrate within a forensic casework context is also presented.
authors.affiliation: Analytical & Environmental Sciences Division, King's College London, 150 Stamford Street, Waterloo, SE19NH, London. nunzianda.frascione@kcl.ac.uk.
authors.forename: J
authors.initials: J
authors.lastname: Gooch
authors.forename: V
authors.initials: V
authors.lastname: Abbate
authors.forename: B
authors.initials: B
authors.lastname: Daniel
authors.forename: N
authors.initials: N
authors.lastname: Frascione
mesh_terms: D005456:Fluorescent Dyes / Q000138:chemical synthesis* / Q000737:chemistry; D044707:Forensic Sciences; D006801:Humans; D017430:Prostate-Specific Antigen / Q000032:analysis / Q000737:chemistry; D012235:Rhodamines / Q000138:chemical synthesis* / Q000737:chemistry; D012661:Semen / Q000737:chemistry; D060327:Solid-Phase Synthesis Techniques; D013050:Spectrometry, Fluorescence
chemical_list: D005456:Fluorescent Dyes; D012235:Rhodamines; C049025:rhodamine 110; D017430:Prostate-Specific Antigen