title: Schnitzler Syndrome: A Dramatic Response to Anakinra.
abstract: Schnitzler syndrome is a rare acquired systemic disease with a chronic evolution and difficult treatment. We report a 50-year-old woman with Schnitzler syndrome for 10 years, with major impact on her quality of life and refractory to conventional therapies. The patient was started on anakinra, an IL-1 receptor antagonist, with a rapid and sustained remission of the syndrome manifestations.
authors.affiliation: Hospital de Santa Maria, University Clinic of Dermatology, Lisbon, Portugal. anaisabelgouveia@hotmail.com.
authors.forename: Ana Isabel
authors.initials: AI
authors.lastname: Gouveia
authors.affiliation: Instituto Português de Reumatologia, Lisbon, Portugal.
authors.forename: Manuela
authors.initials: M
authors.lastname: Micaelo
authors.affiliation: Department of Hematology, Instituto Português de Oncologia de Lisboa, Francisco Gentil, Lisbon, Portugal.
authors.forename: Francesca
authors.initials: F
authors.lastname: Pierdomenico
authors.affiliation: Hospital de Santa Maria, University Clinic of Dermatology, Lisbon, Portugal.
authors.forename: João Pedro
authors.initials: JP
authors.lastname: Freitas
keywords: Anakinra; Schnitzler syndrome; Urticaria