title: The relationship between coronary atherosclerosis and body fat distribution measured using dual energy X-ray absorptiometry.
abstract: OBJECTIVE
  Body fat distribution is closely related to cardiovascular diseases. We aimed to evaluate the relationship between truncal fat distribution and the extent of coronary atherosclerosis.
  
  
  METHODS
  Total body fat and regional body fat distributions were measured using dual-energy X-ray absorptiometry (DXA) in 746 Korean patients who underwent coronary angiography. The ratios of truncal fat mass to total body fat mass (FMtrunk/FMtotal), truncal fat mass to fat mass in both legs (FMtrunk/FMleg) and truncal fat mass to fat mass in both arms (FMtrunk/FMarm) were calculated as representative parameters for truncal fat accumulation. The extent of coronary atherosclerosis was assessed using the Gensini score.
  
  
  RESULTS
  The mean Gensini score of the patients was 21.3 ± 24.4. FMtrunk/FMtotal, FMtrunk/FMleg and FMtrunk/FMarm revealed positive correlations with the Gensini score (r = 0.242, p < 0.001; r = 0.219, p < 0.001; r = 0.133, p < 0.001, respectively). In contrast, body mass index (BMI) and total body fat mass did not correlate with the Gensini score. On multiple regression analysis, FMtrunk/FMtotal was associated with the Gensini score independently of age, gender, BMI and major risk factors of coronary heart disease (B = 0.039, p < 0.001).
  
  
  CONCLUSIONS
  Truncal fat distribution is associated with the extent of coronary atherosclerosis and more clinically relevant to that compared with total body fat or BMI in Korean patients.
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea; Division of Cardiology, Cardiovascular Center, Chun-Cheon Sacred Heart Hospital, Hallym University College of Medicine, 77 Sakju-Ro, Chun-Cheon 24253, Republic of Korea.
authors.forename: Se-Jun
authors.initials: SJ
authors.lastname: Park
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Hyoung-Mo
authors.initials: HM
authors.lastname: Yang
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Kyoung-Woo
authors.initials: KW
authors.lastname: Seo
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: So-Yeon
authors.initials: SY
authors.lastname: Choi
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Byoung-Joo
authors.initials: BJ
authors.lastname: Choi
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Myeong-Ho
authors.initials: MH
authors.lastname: Yoon
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Gyo-Seung
authors.initials: GS
authors.lastname: Hwang
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Seung-Jea
authors.initials: SJ
authors.lastname: Tahk
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea.
authors.forename: Seung-Soo
authors.initials: SS
authors.lastname: Sheen
authors.affiliation: Department of Cardiology, Medical College of Wisconsin, Milwaukee, WI 53266, USA.
authors.forename: Byung-Il W
authors.initials: BI
authors.lastname: Choi
authors.affiliation: Department of Cardiology, Ajou University School of Medicine, 164 Worldcup-Ro, Suwon 16499, Republic of Korea. Electronic address: hslimmd@gmail.com.
authors.forename: Hong-Seok
authors.initials: HS
authors.lastname: Lim
mesh_terms: D015502:Absorptiometry, Photon; D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000378:metabolism*; D050154:Adiposity; D000368:Aged; D015992:Body Mass Index; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000378:metabolism; D012044:Regression Analysis; D056910:Republic of Korea; D013909:Thorax / Q000000981:diagnostic imaging
keywords: Atherosclerosis; Body fat distribution; Gensini score; Obesity