title: Vaccines against 'the other' Ebolavirus species.
abstract: The Ebolavirus genus includes five member species, all of which pose a threat to global public health. These viruses cause fatal hemorrhagic fever in humans and nonhuman primates, and are considered category A pathogens due to the risk of their use as a bioweapon. The potential for an outbreak, either as a result of a natural emergence, deliberate release, or imported case underscores the need for protective vaccines. Recent progress in advancing vaccines for use against the strain of Zaire ebolavirus (EBOV) responsible for the West African Ebola outbreak offers reasons for optimism against EBOV, and demonstrates that protection against other Ebolavirus species is achievable.
authors.affiliation: a Special Pathogens Program, National Microbiology Laboratory , Public Health Agency of Canada , Winnipeg , Canada.|b Department of Medical Microbiology , University of Manitoba , Winnipeg , Canada.
authors.forename: Robert A
authors.initials: RA
authors.lastname: Kozak
authors.affiliation: a Special Pathogens Program, National Microbiology Laboratory , Public Health Agency of Canada , Winnipeg , Canada.|b Department of Medical Microbiology , University of Manitoba , Winnipeg , Canada.|c Department of Pathology and Laboratory Medicine , University of Pennsylvania School of Medicine , Philadelphia , PA , USA.
authors.forename: Gary P
authors.initials: GP
authors.lastname: Kobinger
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D046129:Ebola Vaccines / Q000276:immunology* / Q000302:isolation & purification*; D029043:Ebolavirus / Q000276:immunology*; D019142:Hemorrhagic Fever, Ebola / Q000517:prevention & control* / Q000821:virology; D006801:Humans
chemical_list: D046129:Ebola Vaccines
keywords: Bundibugyo ebolavirus; Reston ebolavirus; Sudan ebolavirus; non-human primates; vaccines