title: A high sensitivity field effect transistor biosensor for methylene blue detection utilize graphene oxide nanoribbon.
abstract: In this work, we developed a field effect transistor (FET) biosensor utilizing solution-processed graphene oxide nanoribbon (GONR) for methylene blue (MB) sensing. MB is a unique material; one of its crucial applications is as a marker in the detection of biomaterials. Therefore, a highly sensitive biosensor with a low detection limit that can be fabricated simply in a noncomplex detection scheme is desirable. GONR is made by unzipping multiwall carbon nanotubes, which can be mass-produced at low temperature. The GONR-FET biosensor demonstrated a sensitivity of 12.5μA/mM (determined according to the drain current difference caused by the MB concentration change). The Raman spectra indicate that the materials quality of the GONR and the domain size for the C=C sp2bonding were both improved after MB detection. X-ray photoelectron spectroscopy revealed that the hydroxyl groups on the GONR were removed by the reductive MB. According to XPS and Raman, the positive charge is proposed to transfer from MB to GONR during sensing. This transfer causes charge in-neutrality in the GONR which is compensated by releasing •OH functional groups. With high sensitivity, a low detection limit, and a simple device structure, the GONR-FET sensor is suitable for sensing biomaterials.
authors.affiliation: Department of Electrical Engineering, National Chung Hsing University, Taichung 40227, Taiwan.
authors.forename: Ting-Chun
authors.initials: TC
authors.lastname: Lin
authors.affiliation: Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
authors.forename: Yan-Sheng
authors.initials: YS
authors.lastname: Li
authors.affiliation: Department of Chemical Engineering, National Taiwan University of Science and Technology, Taipei 10607, Taiwan.
authors.forename: Wei-Hung
authors.initials: WH
authors.lastname: Chiang
authors.affiliation: Department of Electrical Engineering, National Chung Hsing University, Taichung 40227, Taiwan; Graduate Institute of Optoelectronic Engineering, National Chung Hsing University, Taichung 40227, Taiwan. Electronic address: zingway@dragon.nchu.edu.tw.
authors.forename: Zingway
authors.initials: Z
authors.lastname: Pei
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D055664:Electrochemical Techniques / Q000295:instrumentation; D004867:Equipment Design; D006108:Graphite / Q000737:chemistry*; D008751:Methylene Blue / Q000032:analysis*; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D010087:Oxides / Q000737:chemistry; D014173:Transistors, Electronic
chemical_list: D010087:Oxides; D006108:Graphite; D008751:Methylene Blue
keywords: Field effect transistor; Graphene oxide nanoribbon; Methylene blue; Sensitivity