title: Verification of I-125 brachytherapy source strength for use in radioactive seed localization procedures.
abstract: A general-purpose nuclear medicine dose calibrator was assessed as a potential replacement for a dedicated air-communicating well-type ionization chamber (brachytherapy source strength verification instrument) for (125)I seed source strength verification for radioactive seed localization, where less stringent accuracy tolerances may be acceptable. The accuracy, precision and reproducibility of the dose calibrator were measured and compared to regulatory requirements. The results of this work indicate that a dose calibrator can be used for (125)I seed source strength verification for radioactive seed localization.
authors.affiliation: Department of Environmental Health and Safety, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030-4009, USA. Electronic address: jpmetyko@mdanderson.org.
authors.forename: John
authors.initials: J
authors.lastname: Metyko
authors.affiliation: Department of Imaging Physics Department, MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030-4009, USA. Electronic address: werwin@mdanderson.org.
authors.forename: William
authors.initials: W
authors.lastname: Erwin
authors.affiliation: University of Texas, Nuclear Engineering Teaching Lab, 10,100 Burnet Road, Building 159, Austin, TX 78758, USA. Electronic address: s.landsberger@mail.utexas.edu.
authors.forename: Sheldon
authors.initials: S
authors.lastname: Landsberger
mesh_terms: D001918:Brachytherapy / Q000379:methods* / Q000706:statistics & numerical data; D002138:Calibration; D006801:Humans; D007457:Iodine Radioisotopes / Q000008:administration & dosage* / Q000627:therapeutic use; D011874:Radiometry / Q000295:instrumentation; D011879:Radiotherapy Dosage; D015203:Reproducibility of Results
chemical_list: D007457:Iodine Radioisotopes
keywords: Dose calibrator; Radioactive seed localization; Source strength verification