title: 1,1-Disubstituted olefin synthesis via Ni-catalyzed Markovnikov hydroalkylation of alkynes with alkyl halides.
abstract: A Ni-catalyzed Markovnikov hydroalkylation of alkynes with alkyl halides is described. The reaction proceeds smoothly without the use of sensitive organometallic reagents and shows good functional-group compatibility, enabling the efficient synthesis of a variety of 1,1-disubstituted olefins. It also provides a straightforward approach for the modification of complex organic molecules.
authors.affiliation: Hefei National Laboratory for Physical Sciences at the Microscale, iChEM, CAS Key Laboratory of Urban Pollutant Conversion, Anhui Province Key Laboratory of Biomass Clean Energy, University of Science and Technology of China, Hefei 230026, China. binxiao@ustc.edu.cn fuyao@ustc.edu.cn.
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Lu
authors.forename: Jing-Hui
authors.initials: JH
authors.lastname: Liu
authors.forename: Xi
authors.initials: X
authors.lastname: Lu
authors.forename: Zheng-Qi
authors.initials: ZQ
authors.lastname: Zhang
authors.forename: Tian-Jun
authors.initials: TJ
authors.lastname: Gong
authors.forename: Bin
authors.initials: B
authors.lastname: Xiao
authors.forename: Yao
authors.initials: Y
authors.lastname: Fu