title: Early antiretroviral therapy initiation in west Africa has no adverse social consequences: a 24-month prospective study.
abstract: Based on social indicators collected within the TEMPRANO-ANRS12136 trial, we assessed the social consequences of early antiretroviral therapy (ART) initiation in west Africa. We did not observe any significant differences in the levels or the time trends of various social indicators, including union status, HIV disclosure and HIV-related discrimination, between early and deferred ART initiation. Early ART does not carry detectable adverse social consequences that could impair its clinical and preventive benefits.
authors.affiliation: aMRC Centre for Outbreak Analysis, Department of Infectious Diseases Epidemiology, Imperial College London, London, UKbProgramme PAC-CI/ANRS Research Site, CHU de Treichville, Abidjan, Côte d'IvoirecCentre Inserm 1219, Bordeaux University, Bordeaux, FrancedDépartement de Dermatologie et Infectiologie, UFR Sciences Médicales Université Félix Houphouët-BoignyeService des Maladies Infectieuses et Tropicales, CHU de Treichville, Abidjan, Côte d'IvoirefINSERM, UMR_S 1136gSorbonne Universités, UPMC Univ Paris 06, UMR_S 1136, ParishEpidemiology of Occupational and Social Determinants of Health, Centre for Research in Epidemiology and Population Health, INSERM U1018iUMRS 1018, Université Versailles Saint-Quentin, VillejuifjIRD, CEPED, UMR 196 Université Paris Descartes-IRD, Sorbonne Paris Cités, Paris, France.
authors.forename: Kévin
authors.initials: K
authors.lastname: Jean
authors.forename: Serge
authors.initials: S
authors.lastname: Niangoran
authors.forename: Christine
authors.initials: C
authors.lastname: Danel
authors.forename: Raoul
authors.initials: R
authors.lastname: Moh
authors.forename: Gérard Menan
authors.initials: GM
authors.lastname: Kouamé
authors.forename: Anani
authors.initials: A
authors.lastname: Badjé
authors.forename: Delphine
authors.initials: D
authors.lastname: Gabillard
authors.forename: Serge
authors.initials: S
authors.lastname: Eholié
authors.forename: Rosemary
authors.initials: R
authors.lastname: Dray-Spira
authors.forename: France
authors.initials: F
authors.lastname: Lert
authors.forename: Xavier
authors.initials: X
authors.lastname: Anglaret
authors.forename: Annabel
authors.initials: A
authors.lastname: Desgrées-Du-LoÛ
mesh_terms: D000354:Africa, Western; D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D015658:HIV Infections / Q000188:drug therapy*; D006801:Humans; D011446:Prospective Studies; D012929:Psychological Distance; D055502:Secondary Prevention / Q000379:methods*
chemical_list: D044966:Anti-Retroviral Agents