title: Visual Functioning and Health-related Quality-of-Life are Compromised in Patients with Uveitis.
abstract: OBJECTIVE
  To assess the vision-related (VR) and health-related (HR) quality-of-life (QoL) of patients with uveitis.
  
  
  METHODS
  In total, 60 patients with uveitis, 81 patients with diabetic retinopathy (DR), and 70 healthy subjects completed the National Eye Institute Visual Functioning Questionnaire and the Medical Outcome Study 36-Item Short Form.
  
  
  RESULTS
  Patients with uveitis reported lower HR- and VR-QoL than healthy subjects (p<0.05) and lower VR-QoL (p<0.001) than patients with DR. For patients with uveitis, multiple linear regression analyses indicated that lower HR-QoL scores were predicted by younger age (p<0.01), while lower VR-QoL scores were predicted by poorer visual acuity (p<0.001), ocular comorbidities (p<0.05), and female sex (p<0.05).
  
  
  CONCLUSIONS
  Patients with uveitis have significantly poorer VR- and HR-QoL than healthy control subjects. Uveitis has a more debilitating impact on VR-QoL than DR.
authors.affiliation: a School of Medical Science , Faculty of Medicine (UNSW) , Kensington , New South Wales , Australia.
authors.forename: Michelle M
authors.initials: MM
authors.lastname: Hui
authors.affiliation: a School of Medical Science , Faculty of Medicine (UNSW) , Kensington , New South Wales , Australia.|b Department of Ophthalmology , St Vincent's Hospital , Darlinghurst , New South Wales , Australia.
authors.forename: Denis
authors.initials: D
authors.lastname: Wakefield
authors.affiliation: c Hornsby Eye Specialists , Hornsby , New South Wales , Australia.
authors.forename: Ilesh
authors.initials: I
authors.lastname: Patel
authors.affiliation: e School of Psychiatry, University of New South Wales , Kensington , New South Wales , Australia.
authors.forename: Erin
authors.initials: E
authors.lastname: Cvejic
authors.affiliation: a School of Medical Science , Faculty of Medicine (UNSW) , Kensington , New South Wales , Australia.|b Department of Ophthalmology , St Vincent's Hospital , Darlinghurst , New South Wales , Australia.|g Save Sight Institute, University of Sydney , Sydney , New South Wales , Australia.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: McCluskey
authors.affiliation: a School of Medical Science , Faculty of Medicine (UNSW) , Kensington , New South Wales , Australia.|d Retina and Vitreous Centre , Strathfield , New South Wales , Australia.|f Marsden Eye Specialists , Parramatta , New South Wales , Australia.
authors.forename: John H
authors.initials: JH
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003930:Diabetic Retinopathy / Q000503:physiopathology / Q000523:psychology; D005260:Female; D006304:Health Status; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life / Q000523:psychology*; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014605:Uveitis / Q000503:physiopathology* / Q000523:psychology*; D014792:Visual Acuity / Q000502:physiology*; D055815:Young Adult
keywords: Diabetic retinopathy; ocular inflammation; quality-of-life; uveitis