title: Evaluation of Ag containing hydroxyapatite coatings to the Candida albicans infection.
abstract: In this research work, the synthesis of Ag doped hydroxyapatite coatings for dental or orthopedic implants was performed. The main goal was to determine the influence of Ag content on the roughness and antimicrobial performance of the prepared thin films. The films were deposited on Ti6Al4V alloy by means of RF magnetron sputtering. Those coatings were characterized by X-ray diffraction (XRD) and 3D surface profilometry. The antifungal activity after 1 and 7days of culture was evaluated in the presence of Candida albicans (ATCC - 10231). The increase of Ag content increased roughness and reduced the antifungal activity. The results showed that the Ag doped hydroxyapatite coatings can be a potential solution for the improvement of the antifungal activities of Ti based alloy.
authors.affiliation: University Politehnica of Bucharest, 313 Spl. Independentei, 060042 Bucharest, Romania.
authors.forename: S
authors.initials: S
authors.lastname: Ciuca
authors.affiliation: Transilvania University of Brasov, Faculty of Medicine, 29 Bdul Eroilor, 500039 Brasov, Romania. Electronic address: mihaela.badea@unitbv.ro.
authors.forename: M
authors.initials: M
authors.lastname: Badea
authors.affiliation: Transilvania University of Brasov, Faculty of Medicine, 29 Bdul Eroilor, 500039 Brasov, Romania.
authors.forename: E
authors.initials: E
authors.lastname: Pozna
authors.affiliation: National Institute for Optoelectronics, 409 Atomistilor St., 077125 Magurele, Romania.
authors.forename: I
authors.initials: I
authors.lastname: Pana
authors.affiliation: National Institute for Optoelectronics, 409 Atomistilor St., 077125 Magurele, Romania.
authors.forename: A
authors.initials: A
authors.lastname: Kiss
authors.affiliation: Transilvania University of Brasov, Faculty of Electrical Engineering and Computers, 29 Bdul Eroilor, 500039 Brasov, Romania.
authors.forename: L
authors.initials: L
authors.lastname: Floroian
authors.affiliation: University Politehnica of Bucharest, 313 Spl. Independentei, 060042 Bucharest, Romania.
authors.forename: A
authors.initials: A
authors.lastname: Semenescu
authors.affiliation: University Politehnica of Bucharest, 313 Spl. Independentei, 060042 Bucharest, Romania.
authors.forename: C M
authors.initials: CM
authors.lastname: Cotrut
authors.affiliation: Transilvania University of Brasov, Faculty of Medicine, 29 Bdul Eroilor, 500039 Brasov, Romania.
authors.forename: M
authors.initials: M
authors.lastname: Moga
authors.affiliation: National Institute for Optoelectronics, 409 Atomistilor St., 077125 Magurele, Romania.
authors.forename: A
authors.initials: A
authors.lastname: Vladescu
mesh_terms: D000497:Alloys; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D002176:Candida albicans / Q000187:drug effects*; D002177:Candidiasis / Q000382:microbiology; D020099:Coated Materials, Biocompatible / Q000737:chemistry* / Q000494:pharmacology; D015921:Dental Implants; D017886:Durapatite / Q000737:chemistry* / Q000494:pharmacology; D004574:Electromagnetic Fields; D019736:Prostheses and Implants; D012834:Silver / Q000032:analysis / Q000737:chemistry / Q000494:pharmacology*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry
chemical_list: D000497:Alloys; D000935:Antifungal Agents; D020099:Coated Materials, Biocompatible; D015921:Dental Implants; C031462:titanium alloy (TiAl6V4); D012834:Silver; D017886:Durapatite; D014025:Titanium
keywords: Biomedical applications; Magnetron sputtering; Roughness; Silver