title: Hepatic Perfusion Therapy.
abstract: Isolated hepatic perfusion uses the unique vascular supply of hepatic malignancies to deliver cytotoxic chemotherapy. The procedure involves vascular isolation of the liver and delivery of chemotherapy via the hepatic artery and extraction from retrohepatic vena cava. Benefits of hepatic perfusion have been observed in hepatic metastases of ocular melanoma and colorectal cancer and primary hepatocellular carcinoma. Percutaneous and prophylactic perfusions are avenues of ongoing research.
authors.affiliation: Division of Surgical Oncology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: Rahul
authors.initials: R
authors.lastname: Rajeev
authors.affiliation: Division of Surgical Oncology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA.
authors.forename: T Clark
authors.initials: TC
authors.lastname: Gamblin
authors.affiliation: Division of Surgical Oncology, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA. Electronic address: kturaga@mcw.edu.
authors.forename: Kiran K
authors.initials: KK
authors.lastname: Turaga
mesh_terms: D010478:Chemotherapy, Cancer, Regional Perfusion / Q000379:methods; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy*; D018579:Patient Selection
keywords: Colorectal cancer; Hepatic metastases; Hepatocellular carcinoma; Isolated hepatic perfusion; Melanoma; Percutaneous hepatic perfusion; Regional therapies