title: Prognostic value of funisitis and/or chorionic vasculitis compared to histologic chorioamnionitis in full-term infants.
abstract: OBJECTIVE
  To compare pathological findings in the placenta and cord with the prognosis of full-term infants in cases of neonatal infection and microbial analyses.
  
  
  METHODS
  The pathological findings in the placenta and cord and microbial analyses of amniotic fluid and neonatal samples based on culture or polymerase chain reaction (PCR) were observed in 1208 full-term mother-infant pairs at our center. We also collected neonatal clinical infection data, such as the occurrence of septicemia and other infectious diseases.
  
  
  RESULTS
  Neonatal infection and positive identification of microorganisms were more common in the funisitis and/or chorionic vasculitis group than in the histologic chorioamnionitis group.
  
  
  CONCLUSIONS
  Funisitis and/or chorionic vasculitis is a valuable pathological marker for assessing the comparison between intrauterine infection and neonatal inflammatory conditions in infants delivered at full-term.
authors.affiliation: a Department of Pathology , School of Medicine, Xi'an Jiaotong University , Xi'an , China.|b Department of Pathology , Maternity and Children Hospital of Shannxi Province , Xi'an , China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Du
authors.affiliation: a Department of Pathology , School of Medicine, Xi'an Jiaotong University , Xi'an , China.
authors.forename: Enqi
authors.initials: E
authors.lastname: Liu
authors.affiliation: a Department of Pathology , School of Medicine, Xi'an Jiaotong University , Xi'an , China.
authors.forename: Changfu
authors.initials: C
authors.lastname: Xu
authors.affiliation: a Department of Pathology , School of Medicine, Xi'an Jiaotong University , Xi'an , China.
authors.forename: Sihai
authors.initials: S
authors.lastname: Zhao
authors.affiliation: c Department of Gynaecology and Obstetrical , and.
authors.forename: Han
authors.initials: H
authors.lastname: Xiang
authors.affiliation: d Department of Neonatology , Maternity and Children Hospital of Shannxi Province , Xi'an , China.
authors.forename: Zhang
authors.initials: Z
authors.lastname: Li
mesh_terms: D000328:Adult; D000653:Amniotic Fluid / Q000382:microbiology; D000704:Analysis of Variance; D016009:Chi-Square Distribution; D002821:Chorioamnionitis / Q000175:diagnosis*; D002823:Chorion / Q000473:pathology*; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D010920:Placenta / Q000473:pathology*; D011247:Pregnancy; D011379:Prognosis; D011446:Prospective Studies; D012372:ROC Curve; D014470:Umbilical Cord / Q000473:pathology*; D014657:Vasculitis / Q000175:diagnosis*
keywords: Full-term delivery; funisitis and/or chorionic vasculitis; histologic chorioamnionitis; intrauterine infection; microbial analysis; neonatal infection