title: Ataxia telangiectasia, Menkes kinky hair disease and neurocutaneous melanosis.
abstract: This article explores three neurocutaneous syndromes (NCSs), i.e. genetic disorders producing developmental abnormalities of the skin and an increased risk of neurological complications. In this review, different aspects of ataxia telangiectasia, Menkes kinky hair disease and neurocutaneous melanosis are examined: clinical features, genetic defect, mutation spectrum, pathogenesis, and neurobiological basis; indications for clinical practice are also provided to the readers. The aim of this review is to stress the importance of cooperation among dermatologists, neurologists and psychiatrists, in order to provide patients suffering from these diseases with timely diagnosis and targeted treatments.
authors.affiliation: Department of Mental and Physical Health and Preventive Medicine, Second University of Naples, Naples, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Caccavale
authors.affiliation: Department of Mental and Physical Health and Preventive Medicine, Second University of Naples, Naples, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Bove
authors.affiliation: Department of Mental and Physical Health and Preventive Medicine, Second University of Naples, Naples, Italy.|Fusis Association for Research in Child and Adolescent Neuropsychiatry, Alvignano, Italy.
authors.forename: Rocco M
authors.initials: RM
authors.lastname: Bove
authors.affiliation: Section of Psychiatry and Clinical Psychology, Department of Clinical and Experimental Sciences, University of Foggia, Foggia, Italy - maddafly87@libero.it.
authors.forename: Maddalena
authors.initials: M
authors.lastname: LA Montagna
mesh_terms: D001260:Ataxia Telangiectasia / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D003299:Cooperative Behavior; D006801:Humans; D033183:Interdisciplinary Communication; D008548:Melanosis / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D007706:Menkes Kinky Hair Syndrome / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D020752:Neurocutaneous Syndromes / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy