title: FACTORS RELATED TO ORAL CANDIDIASIS IN ELDERLY USERS AND NON-USERS OF REMOVABLE DENTAL PROSTHESES.
abstract: This study examined the association between oral candidiasis in elderly users and nonusers of prosthesis and its predisposing factors. To this end, we performed a cross-sectional study where saliva samples from 48 patients were collected they used prosthesis and 43 patients (control group) who did not use. Among the 91 patients, Candida spp were isolated in 40 (83.3%) who used prosthesis and in 23 (53.5%) in the control group. A statistically significant association was determined between the two groups, the isolation of yeasts and dental prosthesis (p < 0.05, OR = 4.3). The most common etiological agent was Candida albicans (37 isolates), with 23 (62.2%) in the denture group and 14 (37.8%) (control group). Among patients who presented clinical manifestations of oral candidiasis (n = 24), 83.3% (n = 20) belonged to the group that wore dentures, while only 16.7% (n = 4) belonged to the control group. Elderly patients with diabetes had 4.4 times higher estimated risk of developing oral candidiasis when compared with individuals without this condition. There was no statistically significant association between being user prostheses and have diabetes with the onset of candidiasis. No statistically significant association was determined between xerostomia, use of prosthesis and oral candidiasis. The use of prosthetics and poor oral hygiene in elderly patients predisposes to the development of oral candidiasis.
authors.affiliation: Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil, cyrabianchi@terra.com.br.
authors.forename: Cyra Maria Pires de Carvalho
authors.initials: CM
authors.lastname: Bianchi
authors.affiliation: Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil, hbianchi@terra.com.br.
authors.forename: Hélcio Aparecido
authors.initials: HA
authors.lastname: Bianchi
authors.affiliation: Laboratory of Mycology, University Hospital Júlio Muller, Cuiabá, Mato Grosso, Brazil, mokacba@terra.com.br.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tadano
authors.affiliation: Institute of Biomedical Sciences, Federal University of São Paulo, SP, Brazil, crpmicol@uol.com.br.
authors.forename: Claudete Rodrigues de
authors.initials: CR
authors.lastname: Paula
authors.affiliation: Laboratory of Investigation and Mycology, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil, biohoffmann@gmail.com.
authors.forename: Hugo Dias
authors.initials: HD
authors.lastname: Hoffmann-Santos
authors.affiliation: Laboratory of Investigation and Mycology, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil, djbiologico@gmail.com.
authors.forename: Diniz Pereira
authors.initials: DP
authors.lastname: Leite
authors.affiliation: Laboratory of Investigation and Mycology, Faculty of Medicine, Federal University of Mato Grosso, Cuiabá, Mato Grosso, Brazil, rchahn@terra.com.br.
authors.forename: Rosane Christine
authors.initials: RC
authors.lastname: Hahn
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002176:Candida albicans / Q000302:isolation & purification*; D002180:Candidiasis, Oral / Q000453:epidemiology / Q000209:etiology*; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D017266:Dental Prosthesis / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000382:microbiology; D012463:Saliva / Q000382:microbiology; D013282:Stomatitis, Denture / Q000453:epidemiology / Q000382:microbiology*