title: COMPARATIVE STUDY OF MICROANASTOMOSIS WITH DISTINCT 10-0 NYLON SUTURES IN RATS.
abstract: OBJECTIVE
  The aim of this study is to compare micro-sutures commonly used in our midst.
  
  
  METHODS
  In this double-blind study, 30 Wistar rats were operated randomly divided into three groups matched according to the suture used (Nylon 10-0, 75micron, brands Microsuture((r)), Polysuture((r)) and Ethicon((r))). We analyzed the number of surgical nodes required, bleeding, surgical time and histological evaluation.
  
  
  RESULTS
  There was no significant difference between the amount of stitches of arterial suture per anastomosis. Surgical time was longer in Microsuture((r)) group as compared to Polysuture((r)) (p ≤ 0.05). Bleeding in Microsuture((r)) group was higher when compared to the others (p <0.01). In the histological analysis, the Microsuture((r)) group showed a greater tendency to develop fibrosis and aneurysm in surgical site than the others (p <0.01 and p≤0,05, respectively). Similarly, the Ethicon((r)) group showed less tendency to myointimal proliferation than the rest. (p = 0.025).
  
  
  CONCLUSIONS
  The results confirm the relevance of the choice of surgical thread as an independent determining factor for the success of the procedure, besides serving as a rational subsidy for a better cost-benefit analysis. Level of Evidence I, Experimental Study, Controlled Animal Study.
authors.affiliation: . Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Ortopedia e Traumatologia, São Paulo, SP, Brazil.
authors.forename: Ricardo Teixeira E
authors.initials: RT
authors.lastname: Silva
authors.affiliation: . Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Ortopedia e Traumatologia, São Paulo, SP, Brazil.
authors.forename: Thiago Felipe Santos
authors.initials: TF
authors.lastname: Barros
authors.affiliation: . Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Ortopedia e Traumatologia, São Paulo, SP, Brazil.
authors.forename: José Thomé
authors.initials: JT
authors.lastname: de Carvalho
authors.affiliation: . Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Ortopedia e Traumatologia, São Paulo, SP, Brazil.
authors.forename: André Araújo
authors.initials: AA
authors.lastname: Ribeiro
authors.affiliation: . Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Ortopedia e Traumatologia, São Paulo, SP, Brazil.
authors.forename: André Fernandes
authors.initials: AF
authors.lastname: Pires
authors.affiliation: . Universidade de São Paulo, Faculdade de Medicina, Hospital das Clínicas, Instituto de Ortopedia e Traumatologia, São Paulo, SP, Brazil.
authors.forename: Teng Hsiang
authors.initials: TH
authors.lastname: Wei
keywords: Anastomosis, sugical; Microsurgery; Rats, Wistar; Sutures