title: Loading rates during walking in adolescents with type II osteonecrosis secondary to pelvic osteotomy.
abstract: Although Pemberton osteotomy has shown a high success rate even in older children, the occurrence of osteonecrosis (ON) remains one of the most severe complications, leading to premature osteoarthritis. Patients with type II ON are characterized by a valgus deformity of the proximal femur with altered musculoskeletal conditions, affecting the ability to attenuate or sustain the impulsive loading from the ground reaction force. It remains unclear whether these conditions also predispose these patients to harmful impulsive loadings. This study aimed to bridge the gap by measuring the loading rates in the lower limbs during level walking in adolescents who were treated during their infancy for unilateral developmental dysplasia of the hip by a pelvic osteotomy, with or without having developed type II ON. Patients with type II ON were found to display increased loading rates, not only at both the affected and unaffected hip, but also at other joints of the affected limb during level walking when compared to patients without ON changes (p < 0.05). These results suggest that patients with type II ON may be at a higher risk of developing premature hip osteoarthritis that is closely related to abnormal loading rates during gait. It is suggested that regular monitoring of joint loading rates in patients with type II ON is necessary for early identification of damaging loadings, and that early intervention aimed at reducing these loadings should be considered. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 34:2199-2206, 2016.
authors.affiliation: Department of Orthopaedic Surgery, School of Medicine, National Taiwan University, Taiwan, Republic of China.|Department of Orthopaedic Surgery, National Taiwan University Hospital, Taiwan, Republic of China.
authors.forename: Ting-Ming
authors.initials: TM
authors.lastname: Wang
authors.affiliation: Department of Orthopaedic Surgery, National Taiwan University Hospital, Taiwan, Republic of China.|Institute of Biomedical Engineering, National Taiwan University, Taiwan, Republic of China.
authors.forename: Kuan-Wen
authors.initials: KW
authors.lastname: Wu
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, Taiwan, Republic of China.
authors.forename: Ching-Ru
authors.initials: CR
authors.lastname: Chen
authors.affiliation: Institute of Biomedical Engineering, National Taiwan University, Taiwan, Republic of China.
authors.forename: Shih-Wun
authors.initials: SW
authors.lastname: Hong
authors.affiliation: Department of Orthopaedic Surgery, School of Medicine, National Taiwan University, Taiwan, Republic of China.|Institute of Biomedical Engineering, National Taiwan University, Taiwan, Republic of China.
authors.forename: Tung-Wu
authors.initials: TW
authors.lastname: Lu
authors.affiliation: Department of Orthopaedic Surgery, National Taiwan University Hospital, Taiwan, Republic of China.
authors.forename: Ken N
authors.initials: KN
authors.lastname: Kuo
authors.affiliation: Department of Orthopaedic Surgery, National Taiwan University Hospital, Taiwan, Republic of China.
authors.forename: Shier-Chieg
authors.initials: SC
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D002648:Child; D005260:Female; D006618:Hip Dislocation, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D007596:Joints / Q000503:physiopathology*; D008297:Male; D010020:Osteonecrosis / Q000209:etiology / Q000503:physiopathology*; D010027:Osteotomy / Q000009:adverse effects; D011183:Postoperative Complications / Q000209:etiology / Q000503:physiopathology*; D012189:Retrospective Studies; D016138:Walking / Q000502:physiology; D016474:Weight-Bearing
keywords: developmental dysplasia of the hip; motion analysis; osteonecrosis