title: Lidocaine 5% Medicated Plaster for Spinal Neuropathic Pain.
abstract: Spinal cord injuries frequently determine central pain symptoms that are difficult to control. The authors present the case of a 67-year-old suffering from a pleural mesothelioma. During the disease course, he developed a paraplegia syndrome from mesothelioma compression of the spinal cord at T4-T5 level. Following spinal decompression surgery, the patient presented an intense at-level, superficial neuropathic pain syndrome with allodynia and hyperalgesia. After systemic pharmacological therapies had failed, treatment with lidocaine 5% plaster was initiated. The superficial neuropathic symptoms almost completely disappeared within a few days. The lidocaine topical treatment was continued for months with durable analgesic effect.
authors.forename: Ulderico
authors.initials: U
authors.lastname: Freo
authors.forename: Francesco
authors.initials: F
authors.lastname: Ambrosio
authors.forename: Maurizio
authors.initials: M
authors.lastname: Furnari
authors.forename: Carlo
authors.initials: C
authors.lastname: Ori
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D000779:Anesthetics, Local / Q000008:administration & dosage*; D019299:Decompression, Surgical / Q000379:methods; D006801:Humans; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D008654:Mesothelioma / Q000150:complications; D009437:Neuralgia / Q000188:drug therapy* / Q000209:etiology; D010997:Pleural Neoplasms / Q000150:complications; D013117:Spinal Cord Compression / Q000209:etiology / Q000601:surgery*
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine
keywords: lidocaine medicated plaster; mesothelioma; neuropathic pain; spinal cord injury