title: Synchronous ileal neuroendocrine tumor: diagnosis and treatment. A case report and review of the literature.
abstract: BACKGROUND
  The majority of neuroendocrine tumors (NET) are located in the gastrointestinal tract (67.5%) and in the bronchopulmonary (25.3%).
  
  
  METHODS
  CA, female, 42 years old, profuse diarrhea about two months, cramping for increased peristalsis, vomiting and weight loss. The patient, diagnosed with ileal neuroendocrine tumor, by colonoscopy with biopsy of lesion, therefore came in our unit to be subjected to surgical therapy. Plasma assay Chromogranin A was performed: 160 ng / ml (nv: 15-100 ng / ml). The patient underwent surgery of right hemicolectomy.
  
  
  CONCLUSIONS
  Neuroendocrine tumors although are rare diseases, have an increasing impact, probably by virtue of improved diagnostic methods. In case of profuse diarrhea should be suspected a neuroendocrine tumor. Certainly the diagnosis of certainty is given by histological examination (biopsy or resected nodule).
  
  
  CONCLUSIONS
  After surgical excision is necessary to perform the follow-up of chromogranin A, and, if not executed, perform nuclear medicine examinations such as Octreoscan and PET.
  
  
  BACKGROUND
  Chromogranin A, Neuroendocrine tumor, Octreoscan.
authors.forename: Antonino
authors.initials: A
authors.lastname: Buffone
authors.forename: Dario
authors.initials: D
authors.lastname: Cavallaro
authors.forename: Salvatore
authors.initials: S
authors.lastname: Lo Bianco
authors.forename: Lidia
authors.initials: L
authors.lastname: Puzzo
authors.forename: Pietro
authors.initials: P
authors.lastname: Caglià
authors.forename: Matteo Angelo
authors.initials: MA
authors.lastname: Cannizzaro
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D053379:Chromogranin A / Q000097:blood; D003082:Colectomy; D003113:Colonoscopy; D003967:Diarrhea / Q000209:etiology; D005260:Female; D006801:Humans; D007078:Ileal Neoplasms / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D009363:Neoplasm Proteins / Q000097:blood; D009378:Neoplasms, Multiple Primary / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D018358:Neuroendocrine Tumors / Q000097:blood / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D049268:Positron-Emission Tomography; D012074:Remission Induction; D013004:Somatostatin / Q000031:analogs & derivatives
chemical_list: D014408:Biomarkers, Tumor; D053379:Chromogranin A; D009363:Neoplasm Proteins; D013004:Somatostatin; C081788:pentetreotide