title: [OPIOID-FREE ANESTHESIA, ANALGESIA AND SEDATION IN SURGERY OF HEAD AND NECK TUMOR].
abstract: 62 adult patients had highly traumatic cancer head and neck surgery under multimodal non-opioid general anesthesia consisted of dexmedetomidine, lidocane, nefopam and sevoflurane. 18 patients had been intubatedwith fiber optic bronchoscope because of II-IV grade trismus. 10 patients with laryngeal stenosis had been tracheotomizedfor intubation. All these 28 patients had been sedated with dexmedetomidine, lidocane and small doses (10-20 mg) ketamine additionally to local anesthesia. All these patients maintained consciousness and breathed spontaneously. Propofol and rocuronium preceded tracheal intubation. I.V. infusion of dexmedetomidine and lidocane proceeded additionally to sevoflurane (1-1.5MAC) .during the main surgery procedure course. All 62 cases went and finished uneventfully. Awakening and spontaneous breathing recovered just after the end of the surgery. During two first postoperative days all the patients had persistent i.v. analgesia with 1% lidocaine, nefopam and tenoxycam. On the day. 3 analgesia proceeded with nefopam and tenoxycam i.m. The quality of analgesia was good, with no complications. Only 3 patients had one promedol (trimeperidine) or tramadol iniection at the start-up of this new method of analgesia.
authors.forename: V V
authors.initials: VV
authors.lastname: Balandin
authors.forename: E S
authors.initials: ES
authors.lastname: Gorobec
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000698:Analgesia / Q000379:methods*; D018712:Analgesics, Non-Narcotic / Q000008:administration & dosage / Q000627:therapeutic use*; D000701:Analgesics, Opioid / Q000008:administration & dosage / Q000627:therapeutic use; D000768:Anesthesia, General / Q000379:methods*; D000772:Anesthesia, Local / Q000379:methods; D000779:Anesthetics, Local / Q000008:administration & dosage / Q000627:therapeutic use; D016292:Procedural Sedation / Q000379:methods*; D020927:Dexmedetomidine / Q000008:administration & dosage / Q000627:therapeutic use*; D004359:Drug Therapy, Combination; D006258:Head and Neck Neoplasms / Q000601:surgery*; D006801:Humans; D007442:Intubation, Intratracheal; D008875:Middle Aged; D010149:Postoperative Pain / Q000188:drug therapy; D016896:Treatment Outcome
chemical_list: D018712:Analgesics, Non-Narcotic; D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D020927:Dexmedetomidine