title: Comparison of Subtenon Triamcinolone Acetonide Injection with Topical Nepafenac for the Treatment of Pseudophakic Cystoid Macular Edema.
abstract: OBJECTIVE
  To compare the efficacy and safety of subtenon triamcinolone acetonide (TA) injection with topical nepafenac 0.1% for the treatment of pseudophakic cystoid macular edema (CME).
  
  
  METHODS
  In this prospective study, the TA group comprised 24 eyes and the nepafenac group 24 eyes. Best-corrected visual acuity (BCVA), central retinal thickness (CRT), intraocular pressure measurements, and slit-lamp fundoscopy were performed in all subjects at baseline, 1, 2, 3, and 6 months.
  
  
  RESULTS
  Changes in BCVA and CRT over four follow-up visits were statistically significant (p<0.001). The mean CRT decreased from 513.3 to 318.9 μm in the TA group and from 483.7 to 278.0 μm in the nepafenac group. This reduction was statistically significant (p<0.001 for both groups).
  
  
  CONCLUSIONS
  Our visual and OCT results suggest that both treatment modalities are effective with few side-effects. However, nepafenac is more efficacious than subtenon TA in terms of visual gain and its correlation with the reduction in CRT.
authors.affiliation: a Izmir Bozyaka Training and Research Hospital , Department of Ophthalmology , Izmir , Turkey.
authors.forename: Bora
authors.initials: B
authors.lastname: Yüksel
authors.affiliation: a Izmir Bozyaka Training and Research Hospital , Department of Ophthalmology , Izmir , Turkey.
authors.forename: Umut Duygu
authors.initials: UD
authors.lastname: Uzunel
authors.affiliation: a Izmir Bozyaka Training and Research Hospital , Department of Ophthalmology , Izmir , Turkey.
authors.forename: Süleyman Gökhan
authors.initials: SG
authors.lastname: Kerci
authors.affiliation: a Izmir Bozyaka Training and Research Hospital , Department of Ophthalmology , Izmir , Turkey.
authors.forename: Levent
authors.initials: L
authors.lastname: Sağban
authors.affiliation: a Izmir Bozyaka Training and Research Hospital , Department of Ophthalmology , Izmir , Turkey.
authors.forename: Tuncay
authors.initials: T
authors.lastname: Küsbeci
authors.affiliation: a Izmir Bozyaka Training and Research Hospital , Department of Ophthalmology , Izmir , Turkey.
authors.forename: Tümay
authors.initials: T
authors.lastname: Örsel
mesh_terms: D060433:Administration, Ophthalmic; D000368:Aged; D000369:Aged, 80 and over; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage*; D044482:Benzeneacetamides / Q000008:administration & dosage*; D005260:Female; D005451:Fluorescein Angiography; D005938:Glucocorticoids / Q000008:administration & dosage*; D006801:Humans; D056965:Injections, Intraocular; D008269:Macular Edema / Q000188:drug therapy* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D010648:Phenylacetates / Q000008:administration & dosage*; D011446:Prospective Studies; D019591:Pseudophakia / Q000188:drug therapy* / Q000503:physiopathology; D012160:Retina / Q000187:drug effects / Q000473:pathology; D058475:Tenon Capsule / Q000187:drug effects*; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014222:Triamcinolone Acetonide / Q000008:administration & dosage*; D014792:Visual Acuity / Q000502:physiology
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D044482:Benzeneacetamides; D005938:Glucocorticoids; D010648:Phenylacetates; C414203:nepafenac; D014222:Triamcinolone Acetonide
keywords: Central retinal thickness; cystoid macular edema; nepafenac; pseudophakia; triamcinolone acetonide