title: Ultrasound-Guided Thrombin Injection for the Treatment of Femoral Pseudoaneurysm in Pediatric Patients.
abstract: Eight patients with nine femoral pseudoaneurysms were treated with 13 ultrasound-guided thrombin injections. Mean patient age was 3.3 years (range, 5 mo to 13.6 y), mean pseudoaneurysm diameter was 2.0 cm ± 0.6, and mean thrombin dose was 119 IU (500 IU/mL ± 116; 0.95 CI). Mean follow-up was 27 days (range, 7-120 d). Eight pseudoaneurysms were successfully treated, and one failed to close as a result of arterial wall disease. No complications were observed. The approach used at the authors' pediatric institution resulted in safe and effective treatment of femoral pseudoaneurysms.
authors.affiliation: Division of Imaging Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, ON, Canada M5G 1X8.
authors.forename: Jason J
authors.initials: JJ
authors.lastname: Boubalos
authors.affiliation: Division of Imaging Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, ON, Canada M5G 1X8.
authors.forename: Bairbre L
authors.initials: BL
authors.lastname: Connolly
authors.affiliation: Division of Imaging Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, ON, Canada M5G 1X8.
authors.forename: Joao G
authors.initials: JG
authors.lastname: Amaral
authors.affiliation: Division of Imaging Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, ON, Canada M5G 1X8.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Temple
authors.affiliation: Division of Imaging Guided Therapy, Department of Diagnostic Imaging, The Hospital for Sick Children, University of Toronto, 555 University Ave., Toronto, ON, Canada M5G 1X8. Electronic address: dimitri.parra@sickkids.ca.
authors.forename: Dimitri A
authors.initials: DA
authors.lastname: Parra
mesh_terms: D000293:Adolescent; D000367:Age Factors; D017541:Aneurysm, False / Q000000981:diagnostic imaging / Q000188:drug therapy*; D002648:Child; D002675:Child, Preschool; D005260:Female; D005263:Femoral Artery / Q000000981:diagnostic imaging / Q000187:drug effects*; D006801:Humans; D007223:Infant; D007269:Injections, Intra-Arterial; D008297:Male; D012189:Retrospective Studies; D013917:Thrombin / Q000008:administration & dosage*; D013997:Time Factors; D016896:Treatment Outcome; D018615:Ultrasonography, Doppler, Color; D018084:Ultrasonography, Interventional / Q000379:methods*
chemical_list: D013917:Thrombin