title: Corneal Epithelium Thickness Profile in 614 Normal Chinese Children Aged 7-15 Years Old.
abstract: The purpose of the study is to describe the values and distribution of corneal epithelium thickness (CET) in normal Chinese school-aged children, and to explore associated factors with CET. CET maps were measured by Fourier-domain optical coherence tomography (FD-OCT) in normal Chinese children aged 7 to 15 years old from two randomly selected schools in Shanghai, China. Children with normal intraocular pressure were further examined for cycloplegic autorefraction, corneal curvature radius (CCR) and axial length. Central (2-mm diameter area), para-central (2- to 5-mm diameter area), and peripheral (5- to 6-mm diameter area) CET in the superior, superotemporal, temporal, inferotemporal, inferior, inferonasal, nasal, superonasal cornea; minimum, maximum, range, and standard deviation of CET within the 5-mm diameter area were recorded. The CET was thinner in the superior than in the inferior and was thinner in the temporal than in the nasal. The maximum CET was located in the inferior zone, and the minimum CET was in the superior zone. A thicker central CET was associated with male gender (p = 0.009) and older age (p = 0.037) but not with CCR (p = 0.061), axial length (p = 0.253), or refraction (p = 0.351) in the multiple regression analyses. CCR, age, and gender were correlated with para-central and peripheral CET.
authors.affiliation: Shanghai Eye Hospital, Shanghai Eye Disease Prevention &Treatment Center, No. 380 KangDing Road, Shanghai 200040, China.|Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, No. 100 HaiNing Road, Shanghai 200080, China.
authors.forename: Yingyan
authors.initials: Y
authors.lastname: Ma
authors.affiliation: Shanghai Eye Hospital, Shanghai Eye Disease Prevention &Treatment Center, No. 380 KangDing Road, Shanghai 200040, China.|Department of Maternal and Child Health, School of Public Health, Key Laboratory of Public Health Safety, Ministry of Education, Fudan University, No. 130 DongAn Road, Shanghai 200032, China.
authors.forename: Xiangui
authors.initials: X
authors.lastname: He
authors.affiliation: Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, No. 100 HaiNing Road, Shanghai 200080, China.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Shanghai Eye Hospital, Shanghai Eye Disease Prevention &Treatment Center, No. 380 KangDing Road, Shanghai 200040, China.
authors.forename: Lina
authors.initials: L
authors.lastname: Lu
authors.affiliation: Shanghai Eye Hospital, Shanghai Eye Disease Prevention &Treatment Center, No. 380 KangDing Road, Shanghai 200040, China.
authors.forename: Jianfeng
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Shanghai Eye Hospital, Shanghai Eye Disease Prevention &Treatment Center, No. 380 KangDing Road, Shanghai 200040, China.|Department of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, No. 100 HaiNing Road, Shanghai 200080, China.
authors.forename: Haidong
authors.initials: H
authors.lastname: Zou
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002681:China; D019573:Epithelium, Corneal / Q000000981:diagnostic imaging* / Q000502:physiology; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008297:Male; D012044:Regression Analysis; D012727:Sex Characteristics; D041623:Tomography, Optical Coherence / Q000379:methods*