title: Treatment options for apnoea of prematurity.
abstract: Apnoea of prematurity (AOP) affects almost all infants born at <28 weeks gestation or with birth weight <1000 g. When untreated, AOP may be associated with negative outcomes. Because of these negative outcomes, effective treatment for AOP is an important part of optimising care of preterm infants. Standard treatment usually involves xanthine therapy and respiratory support. Cutting-edge work with stochastic vibrotactile stimulation and new pharmaceutical agents continues to expand therapeutic options. In this article, we review the pathophysiology of AOP, associated conditions and treatment options.
authors.affiliation: Harvard Neonatal-Perinatal Fellowship Program, Boston Children's Hospital Boston, Boston, Massachusetts, USA.
authors.forename: Sarah U
authors.initials: SU
authors.lastname: Morton
authors.affiliation: Department of Neonatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Vincent C
authors.initials: VC
authors.lastname: Smith
mesh_terms: D001049:Apnea / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D019468:Disease Management; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
keywords: Apnea of prematurity; Intensive care, neonatal; review article