title: Umbilical cord and preeclampsia.
abstract: BACKGROUND
  Preeclampsia is associated with abnormalities in the umbilical cord in several ways: morphological, biochemical and functional. Alteration in blood vessels of the placenta, decidua and circulatory system of the fetus might be related to factors that cause preeclampsia and may be associated with alterations of the umbilical cord.
  
  
  OBJECTIVE
  This study aimed to analyze the relationship between each type of umbilical cord abnormality and the different subtypes of hypertensive gestational disorders.
  
  
  METHODS
  We conducted a prospective study on consecutive autopsies and its placentas, looking for abnormalities in the umbilical cord's features and their clinical associations.
  
  
  RESULTS
  Umbilical cord abnormalities including length, diameter, insertion, entanglements, knots and coils were associated with maternal gestational hypertension.
  
  
  CONCLUSIONS
  In women with gestational hypertension, umbilical cord abnormalities are associated with fetal and neonatal consequences.
authors.affiliation: Department of Pathology, Pontificia Universidad Javeriana School of Medicine, Bogota, Colombia- San Ignacio University Hospital, Bogota, Colombia.
authors.forename: M
authors.initials: M
authors.lastname: Olaya-C
authors.affiliation: Pontificia Universidad Javeriana School of Medicine, Bogota, Colombia.
authors.forename: J
authors.initials: J
authors.lastname: Salcedo-Betancourt
authors.affiliation: Pontificia Universidad Javeriana School of Medicine, Bogota, Colombia.
authors.forename: S H
authors.initials: SH
authors.lastname: Galvis
authors.affiliation: Pontificia Universidad Javeriana School of Medicine, Bogota, Colombia.
authors.forename: A M
authors.initials: AM
authors.lastname: Ortiz
authors.affiliation: Pontificia Universidad Javeriana School of Medicine, Bogota, Colombia.
authors.forename: S
authors.initials: S
authors.lastname: Gutierrez
authors.affiliation: Institute of Human Genetics, the Medical School, Pontificia Universidad Javeriana, Bogota, and Universidad Tecnologica de Bolivar en Cartagena de Indias.
authors.forename: J E
authors.initials: JE
authors.lastname: Bernal
mesh_terms: D000328:Adult; D001344:Autopsy; D003105:Colombia; D004108:Dilatation, Pathologic / Q000473:pathology; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology / Q000473:pathology; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D008431:Maternal-Fetal Exchange; D010920:Placenta / Q000098:blood supply / Q000473:pathology; D011225:Pre-Eclampsia / Q000473:pathology*; D011247:Pregnancy; D011446:Prospective Studies; D014470:Umbilical Cord / Q000002:abnormalities* / Q000473:pathology
keywords: HELLP syndrome; Placenta; eclampsia; gestational hypertension; pregnancy