title: Expanding the Genetic Profile of BCC.
abstract: Basal cell carcinoma, the most common form of skin cancer, most often occurs as a result of aberrant Hedgehog signaling. However, new research suggests that additional molecular drivers may be involved, including mutations that lead to N-Myc accumulation and oncogenic YAP1 activity.
mesh_terms: D002280:Basal Cell Carcinoma / Q000235:genetics* / Q000378:metabolism; D002471:Cell Transformation, Neoplastic / Q000235:genetics / Q000378:metabolism; D020869:Gene Expression Profiling; D020022:Genetic Predisposition to Disease; D023281:Genomics / Q000379:methods; D006801:Humans; D009154:Mutation; D012878:Skin Neoplasms / Q000235:genetics* / Q000378:metabolism; D059467:Transcriptome