title: Multidisciplinary management of nonfunctional neuroendocrine tumor of the pancreas.
abstract: Pancreatic neuroendocrine tumors (PNETs) are a rare and diverse group of tumors; nonfunctional (NF) PNETs account for the majority of cases. Most patients with NF-PNETs have metastatic disease at the time of presentation. A variety of treatment modalities exist, including medical, liver directed, and surgical treatments. Aggressive surgical management is associated with prolonged survival, however available data are limited by selection bias and the frequent combination of PNETs with carcinoid tumors. Although few patients with metastatic disease will be cured, application of currently available therapies in a multidisciplinary setting can lead to excellent outcomes with prolonged patient survival.
authors.affiliation: Ian W Folkert, Paul Hernandez, Robert E Roses, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States.
authors.forename: Ian W
authors.initials: IW
authors.lastname: Folkert
authors.affiliation: Ian W Folkert, Paul Hernandez, Robert E Roses, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States.
authors.forename: Paul
authors.initials: P
authors.lastname: Hernandez
authors.affiliation: Ian W Folkert, Paul Hernandez, Robert E Roses, Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, PA 19104, United States.
authors.forename: Robert E
authors.initials: RE
authors.lastname: Roses
mesh_terms: D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging / Q000401:mortality / Q000556:secondary / Q000628:therapy*; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging / Q000401:mortality / Q000473:pathology / Q000628:therapy*; D010348:Patient Care Team; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
keywords: Multidisciplinary; Neuroendocrine tumor; Nonfunctional; Pancreas; Pancreatic neuroendocrine tumor