title: Baseline Predictors for Success Following Strategy-Based Cognitive Remediation Group Training in Schizophrenia.
abstract: Our aim was to examine predictive variables associated with the improvement in cognitive, clinical, and functional outcomes after outpatient participation in REPYFLEC strategy-based Cognitive Remediation (CR) group training. In addition, we investigated which factors might be associated with some long-lasting effects at 6 months' follow-up. Predictors of improvement after CR were studied in a sample of 29 outpatients with schizophrenia. Partial correlations were computed between targeted variables and outcomes of response to explore significant associations. Subsequently, we built linear regression models for each outcome variable and predictors of improvement. The improvement in negative symptoms at posttreatment was linked to faster performance in the Trail Making Test B. Disorganization and cognitive symptoms were related to changes in executive function at follow-up. Lower levels of positive symptoms were related to durable improvements in life skills. Levels of symptoms and cognition were associated with improvements following CR, but the pattern of resulting associations was nonspecific.
authors.affiliation: *Parc Sanitari Sant Joan de Déu, CIBERSAM (Biomedical Research Center in Mental Health Net, Spain), Barcelona, Spain; †Olin Neuropsychiatry Research Center, Institute of Living, Hartford Hospital, Hartford; and ‡Department of Psychiatry, Yale School of Medicine, New Haven, CT.
authors.forename: Aida
authors.initials: A
authors.lastname: Farreny
authors.forename: Jaume
authors.initials: J
authors.lastname: Aguado
authors.forename: Silvia
authors.initials: S
authors.lastname: Corbera
authors.forename: Susana
authors.initials: S
authors.lastname: Ochoa
authors.forename: Elena
authors.initials: E
authors.lastname: Huerta-Ramos
authors.forename: Judith
authors.initials: J
authors.lastname: Usall
mesh_terms: D000328:Adult; D060825:Cognitive Dysfunction / Q000209:etiology / Q000534:rehabilitation*; D000072466:Cognitive Remediation / Q000379:methods*; D056344:Executive Function / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D011615:Psychotherapy, Group / Q000379:methods*; D012559:Schizophrenia / Q000150:complications / Q000534:rehabilitation*