title: Growth and neurodevelopment outcome in symmetric versus asymmetric small for gestational age term infants.
abstract: Few studies compared growth and neurodevelopment outcome between asymmetric (aSYM) and symmetric (SYM) small for gestational age (SGA) term infants. We aimed at evaluating their respective outcome at 9 months postnatal age.
  
  
  
  A cohort study including infants born in 2010 to 2011 with a birth weight <5th centile and a head circumference (HC) below (SYM) or above (aSYM) the 5th centile. Catch-up growth was defined as weight, height and HC ⩾-2 s.d. of World Health Organization reference values. Neurodevelopment was evaluated with Brunet-Lezine test items.
  
  
  
  Of 6586 infants, 194 were SGA: 38.7% SYM and 61.3% aSYM. The aSYM group showed better catch-up growth (85% versus 70%, P=0.03) with larger HC (44.9±1.6 versus 43.7±1.2 cm, P<0.0001). No difference in neurodevelopmental screening was observed between SGA groups, but infants without any catch-up growth were at higher risk of delayed outcome.
  
  
  
  Term SGA infants must be closely followed, regardless of their characteristics, to improve their outcome.
authors.affiliation: Department of Neonatology, Maternité Régionale, CHRU Nancy, Nancy, France.
authors.forename: E
authors.initials: E
authors.lastname: Maciejewski
authors.affiliation: Department of Neonatology, Maternité Régionale, CHRU Nancy, Nancy, France.|Universite de Lorraine, Faculté de Médecine de Nancy, Vandoeuvre-les-Nancy, France.
authors.forename: I
authors.initials: I
authors.lastname: Hamon
authors.affiliation: Department of Medical Information, CHRU Nancy, Nancy, France.
authors.forename: J
authors.initials: J
authors.lastname: Fresson
authors.affiliation: Department of Neonatology, Maternité Régionale, CHRU Nancy, Nancy, France.|Universite de Lorraine, Faculté de Médecine de Nancy, Vandoeuvre-les-Nancy, France.
authors.forename: J-M
authors.initials: JM
authors.lastname: Hascoet
mesh_terms: D001724:Birth Weight; D001827:Body Height; D002508:Cephalometry; D005260:Female; D005317:Fetal Growth Retardation / Q000209:etiology*; D005602:France; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age / Q000254:growth & development*; D008297:Male; D012016:Reference Values; D012189:Retrospective Studies; D047929:Term Birth; D014944:World Health Organization