title: [RETROSPECTIVE DATA ANALYSIS OF THE PATIENTS WITH INFLAMMATORY JOINT DISEASES TREATED WITH GOLIMUMAB IN CROATIA].
abstract: Golimumab is a human monoclonal antibody which inhibits tumor necrosis factor-alpha (TNF-α) and is approved for the treatment of inflammatory arthritides (rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis) when the conventional non-pharmacological and pharmacological therapies fail to cause remission or low disease activity. In this retrospective study there were included patients with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis who were treated in Croatia with golimumab, from June 2011 to June 2013. included and these retrospective data are compared with similar data from clinical trials and other available databases. Standard variables of disease activity and functional ability were observed. Results demonstrated significant efficacy of golimumab regarding lowring the disease activity and imrpving functional ability in pateints with these inflammatory rherumatic disease. In conclusion, in this retrospective study during two years treatment golimumab showed efficacy in decreasing disease activity and imrpove functional ability in patiemts with rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis.
authors.forename: Branimir
authors.initials: B
authors.lastname: Anić
authors.forename: Ðurđica
authors.initials: Ð
authors.lastname: Babić-Naglić
authors.forename: Simeon
authors.initials: S
authors.lastname: Grazio
authors.forename: Tatjana
authors.initials: T
authors.lastname: Kehler
authors.forename: Dusanka Martinović
authors.initials: DM
authors.lastname: Kaliterna
authors.forename: Ksenija Mastrović
authors.initials: KM
authors.lastname: Radoncić
authors.forename: Jadranka
authors.initials: J
authors.lastname: Morović-Vergles
authors.forename: Srđan
authors.initials: S
authors.lastname: Novak
authors.forename: Visnja
authors.initials: V
authors.lastname: Prus
authors.forename: Tonko
authors.initials: T
authors.lastname: Vlak
authors.forename: Marko
authors.initials: M
authors.lastname: Baresić
mesh_terms: D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D015535:Arthritis, Psoriatic / Q000188:drug therapy* / Q000503:physiopathology; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000503:physiopathology; D017523:Croatia; D006801:Humans; D012189:Retrospective Studies; D013167:Spondylitis, Ankylosing / Q000188:drug therapy* / Q000503:physiopathology
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; C529000:golimumab