title: A three-year survey of the antimicrobial resistance of microorganisms at a Chinese hospital.
abstract: The present retrospective study aimed to investigate the antibiotic susceptibility of bacteria at Shanghai First People's Hospital (Shanghai, China) between 2009 and 2011. An increasing trend of antibiotic resistance was observed in this hospital between 2009 and 2011.Escherichia coli,Acinetobacter baumanniiandStaphylococcus aureuswere the most prevalent resistant strains. Antimicrobial susceptibility was detected using standard Kirby-Bauer disk diffusion and analyzed using World Health Organization software.E. coliwas demonstrated to be the most prevalent bacterium in the present survey between 2009 and 2011 (16.2, 20.0 and 19.6%, respectively); followed byA. baumannii(13.5, 13.3 and 10.6%, respectively) andS. aureus. Notably, >70% ofE. coliand 70% ofS. aureuswere resistant to common antibiotics; whereas 60% ofA. baumanniiand 20% ofPseudomonas aeruginosawere resistant to the majority of the antibiotics investigated. In 2011,Enterococcus faecalisexhibited a resistance rate of 55.6% against levofloxacin andE. faeciumexhibited a 53.2% resistance rate. The present survey demonstrated an increasing trend in bacterial resistance against antibiotics; therefore, more stringent guidelines for antibiotics should be advocated.
authors.affiliation: Department of Clinical Pharmacy, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Tang
authors.affiliation: Department of Blood Transfusion, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, P.R. China.
authors.forename: Lili
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Clinical Pharmacy, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, P.R. China.
authors.forename: Yufei
authors.initials: Y
authors.lastname: Xi
authors.affiliation: Department of Clinical Pharmacy, Shanghai First People's Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai 200080, P.R. China.
authors.forename: Gaolin
authors.initials: G
authors.lastname: Liu
keywords: Acinetobacter; Escherichia coli; Staphylococcus aureus; antimicrobial resistance; bacterial infection