title: [Current therapy of polyarticular forms of juvenile idiopathic arthritis].
abstract: Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in infancy and childhood. Approximately 20 % of patients with JIA suffer from the polyarticular form of the disease, which causes a substantial disease burden and long-term sequelae. Therapeutic approaches have used steroids and conventional disease modifying antirheumatic drugs (DMARD) but over the last decade new drugs have become available for the treatment of JIA, in particular biologic DMARD. This article summarizes the current therapy options for polyarticular JIA.
authors.affiliation: Zentrum für Pädiatrische Rheumatologie, Klinikum Stuttgart, Olgahospital, Kriegsbergstr. 62, 70174, Stuttgart, Deutschland. a.hospach@klinikum-stuttgart.de.
authors.forename: A
authors.initials: A
authors.lastname: Hospach
authors.affiliation: Praxis für Kinderheilkunde und Jugendmedizin/Kinderrheumatologie, Göttingen, Deutschland.
authors.forename: J M
authors.initials: JM
authors.lastname: Rühlmann
authors.affiliation: Prof.-Hess-Kinderklinik, Zentrum für Kinderheilkunde und Jugendmedizin, Klinikum Bremen - Mitte, Gesundheit Nord Klinikverbund Bremen, Bremen, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Weller-Heinemann
mesh_terms: D000911:Antibodies, Monoclonal / Q000008:administration & dosage*; D018501:Antirheumatic Agents / Q000008:administration & dosage*; D001168:Arthritis / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control; D001171:Arthritis, Juvenile / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control*; D001688:Biological Products / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D015195:Drug Design; D019317:Evidence-Based Medicine; D006801:Humans; D007167:Immunotherapy / Q000639:trends; D007223:Infant; D007231:Infant, Newborn; D013256:Steroids / Q000008:administration & dosage*; D016896:Treatment Outcome
chemical_list: D000911:Antibodies, Monoclonal; D018501:Antirheumatic Agents; D001688:Biological Products; D013256:Steroids
keywords: Biologics; Disease modifying antirheumatic drugs; Juvenile idiopathic arthritis; Polyarthritis; Therapy