title: [The changes and significance of IL-6 levels in patients with OSAHS associated Type 2 diabetes Mellites].
abstract: OBJECTIVE
  To explore the changes of serum interleukin-6 (IL-6) level in patients with obstructive sleep apnea hypopnea syndrome (OSAHS) and OSAHS associated type 2 diabetes mellitus (T2DM) and their significance.
  
  
  METHODS
  All observed subjects were divided into 3 groups: 20 cases of normal subjects, 35 cases of simple OSAHS patients, 48 cases of OSAHS associated T2DM patients, IL-6 concentrations of serum were measured by the enzyme-linked immunosorbent.
  
  
  RESULTS
  IL-6 level was higher in the group of OSAHS with T2DM than the group of OSAHS and the healthy control group (P < 0.05); IL-6 level was higher in the simple OSAHS group than the healthy controls.
  
  
  CONCLUSIONS
  IL-6 and other inflammatory factors may involved pathological physiological process in OSAHS patients sugar metabolic abnormalities; and is associated with the development of OSAHS associated with type 2 diabetes.
authors.forename: Peilin
authors.initials: P
authors.lastname: Hui
authors.forename: Shuangbao
authors.initials: S
authors.lastname: Jia
authors.forename: Wei
authors.initials: W
authors.lastname: Ma
authors.forename: Lijun
authors.initials: L
authors.lastname: Zhao
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Wang
authors.forename: Xiaoquan
authors.initials: X
authors.lastname: Wei
authors.forename: Liya
authors.initials: L
authors.lastname: Zhou
authors.forename: Manke
authors.initials: M
authors.lastname: Dai
authors.forename: Wenjuan
authors.initials: W
authors.lastname: Zhang
authors.forename: Yuping
authors.initials: Y
authors.lastname: Xie
mesh_terms: D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications; D006801:Humans; D015850:Interleukin-6 / Q000097:blood*; D020181:Sleep Apnea, Obstructive / Q000097:blood* / Q000150:complications
chemical_list: C508600:IL6 protein, human; D015850:Interleukin-6