title: Biosynthesis of silver nanoparticles using Aeromonas sp. THG-FG1.2 and its antibacterial activity against pathogenic microbes.
abstract: Silver nanoparticles were prepared through green route with the aid of Aeromonas sp. THG-FG1.2 as reductant. Visual observation, ultraviolet-visible spectroscopy, transmission electron microscopy, elemental mapping, energy dispersive X-ray spectroscopy, selected area diffraction pattern (SAED), and X-ray diffraction (XRD) were used to characterize the synthesized silver nanoparticles. UV visible studies indicated the surface plasmon resonance at 400 nm which depicts the formation of silver nanoparticles. The TEM images show spherical silver nanoparticles of 8-16 nm. XRD and SAED fringes revealed the structure of silver nanoparticles as face centered cubic (fcc). These silver nanoparticles also tested for their antimicrobial potential and showed effective antimicrobial activity against tested pathogens and thus applicable as potent antimicrobial agent. Furthermore, the nanoparticles potential has been reconnoitered for their enhanced synergistic effect with antibiotics against multidrug resistant bacteria. Thus, the silver nanoparticles synthesized by Aeromonas sp. THG-FG1.2, were effective in inhibition of pathogenic microbes and also show enhanced antibacterial activity with antibiotics.
authors.affiliation: a Department of Oriental Medicine Biotechnology , College of Life Science, Kyung Hee University Global Campus , Yongin-si , R epublic of Korea.
authors.forename: Hina
authors.initials: H
authors.lastname: Singh
authors.affiliation: a Department of Oriental Medicine Biotechnology , College of Life Science, Kyung Hee University Global Campus , Yongin-si , R epublic of Korea.
authors.forename: Juan
authors.initials: J
authors.lastname: Du
authors.affiliation: a Department of Oriental Medicine Biotechnology , College of Life Science, Kyung Hee University Global Campus , Yongin-si , R epublic of Korea.
authors.forename: Tae-Hoo
authors.initials: TH
authors.lastname: Yi
mesh_terms: D000333:Aeromonas / Q000737:chemistry* / Q000502:physiology; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D002175:Candida / Q000187:drug effects / Q000254:growth & development; D052978:Disk Diffusion Antimicrobial Tests; D004357:Drug Synergism; D006090:Gram-Negative Bacteria / Q000187:drug effects / Q000254:growth & development; D006094:Gram-Positive Bacteria / Q000187:drug effects / Q000254:growth & development; D055772:Green Chemistry Technology; D018942:Macrolides / Q000494:pharmacology; D053768:Metal Nanoparticles / Q000737:chemistry / Q000633:toxicity* / Q000648:ultrastructure; D010316:Particle Size; D012835:Silver Nitrate / Q000737:chemistry* / Q000378:metabolism; D014640:Vancomycin / Q000494:pharmacology; D047090:beta-Lactams / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D018942:Macrolides; D047090:beta-Lactams; D014640:Vancomycin; D012835:Silver Nitrate
keywords: Aeromonas sp. THG-FG1.2; antimicrobial effect; biosynthesis; silver nanoparticles