title: The effect of low-volatile organic compounds, water-based paint on aggravation of allergic disease in schoolchildren.
abstract: Whether indoor painting aggravates preexisting allergic diseases remains unclear. We aimed to evaluate the impact of new classroom painting on aggravation of asthma, allergic rhinitis (AR), and atopic dermatitis (AD) in children. Studied school was previously painted with conventional water-based paint 20 years ago and had natural ventilation system. We identified a total of 172 children aged 10-12 years with allergic diseases in 17 classrooms, which were allocated to newly painted rooms with low-volatile organic compounds (VOC), water-based paint, or existing rooms. After painting, there was no intervention or internal airflow to influence indoor air environment in both classrooms. We prospectively assessed the symptom severity and serious events of allergic diseases between both classrooms at baseline and after one and eight weeks after painting. At one and eight weeks, there were no significant changes in the Childhood Asthma Control Test scores, the fractional nitric oxide levels, lung function in asthmatic children in either classroom. There were also no significant changes in the severity score of AR or AD, or serious events in all allergic diseases. These findings suggest classroom painting with this new paint at the levels encountered in this study might not be a major aggravating factor for school-aged children with allergic diseases.
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: D W
authors.identifier: 0000-0002-4538-6045
authors.initials: DW
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: S-H
authors.initials: SH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: J-Y
authors.initials: JY
authors.lastname: Moon
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: J S
authors.initials: JS
authors.lastname: Song
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: J
authors.initials: J
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: H J
authors.initials: HJ
authors.lastname: Kwak
authors.affiliation: Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: M G
authors.initials: MG
authors.lastname: Jeong
authors.affiliation: Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: Y S
authors.initials: YS
authors.lastname: Ro
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: T H
authors.initials: TH
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: J W
authors.initials: JW
authors.lastname: Sohn
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: D H
authors.initials: DH
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: S S
authors.initials: SS
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea.
authors.forename: H J
authors.initials: HJ
authors.lastname: Yoon
mesh_terms: D016902:Air Pollution, Indoor / Q000009:adverse effects* / Q000032:analysis; D001249:Asthma / Q000139:chemically induced; D002648:Child; D003876:Dermatitis, Atopic / Q000139:chemically induced; D005260:Female; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology*; D008297:Male; D010150:Paint / Q000032:analysis / Q000633:toxicity*; D011446:Prospective Studies; D065631:Rhinitis, Allergic / Q000139:chemically induced; D000067251:Symptom Flare Up; D055549:Volatile Organic Compounds / Q000032:analysis / Q000633:toxicity*
chemical_list: D055549:Volatile Organic Compounds
keywords: Allergic rhinitis; Asthma; Atopic dermatitis; Indoor air; Paint