title: Diagnostics for pulmonary tuberculosis.
abstract: Tuberculosis (TB) remains a leading cause of human suffering and mortality despite decades of effective treatment being available. Accurate and timely diagnosis remains an unmet goal. The HIV epidemic has also led to new challenges in the diagnosis of TB. Several new developments in TB diagnostics have the potential to positively influence the global campaign against TB. We aim to review the performance of both established as well as new diagnostics for pulmonary TB in adults, and discuss the ongoing challenges.
authors.affiliation: Section of Infectious Diseases, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Patrick
authors.identifier: http://orcid.org/0000-0003-4462-9567
authors.initials: P
authors.lastname: Cudahy
authors.affiliation: Section of Infectious Diseases, Department of Medicine, Yale University School of Medicine, New Haven, Connecticut, USA.
authors.forename: Sheela V
authors.identifier: http://orcid.org/0000-0001-7654-4344
authors.initials: SV
authors.lastname: Shenoi
mesh_terms: D019411:Clinical Laboratory Techniques; D060085:Coinfection; D003362:Cost-Benefit Analysis; D003906:Developing Countries; D015658:HIV Infections / Q000175:diagnosis* / Q000382:microbiology; D006801:Humans; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D019095:Point-of-Care Systems / Q000191:economics / Q000706:statistics & numerical data; D014397:Tuberculosis, Pulmonary / Q000175:diagnosis* / Q000382:microbiology
keywords: INFECTIOUS DISEASES; PUBLIC HEALTH