title: Surgical Management of Pancreatic Neuroendocrine Tumors.
abstract: Pancreatic neuroendocrine tumors (pancNETs) are rare neoplasms that comprise 2% to 4% of all clinically detected pancreatic tumors. They are usually indolent, and their malignant potential is often underestimated. The management of this disease poses a challenge because of the heterogeneous clinical presentation and varying degree of aggressiveness. Treatment decisions for this clinical entity are still patient- and/or physician-specific. Optimal clinical management of pancNETs requires a multidisciplinary approach. The only potentially curative treatment option, especially in the early stage disease, remains surgical resection; however, as many as 75% of patients present with advanced disease (nodal and/or distant metastases).
authors.affiliation: Department of Surgery, Winship Cancer Institute, Emory University School of Medicine, 1365 C Clifton Road, Northeast, 2nd Floor, Atlanta, GA 30322, USA.
authors.forename: Amareshwar
authors.initials: A
authors.lastname: Chiruvella
authors.affiliation: Department of Surgery, Winship Cancer Institute, Emory University School of Medicine, 1365 C Clifton Road, Northeast, 2nd Floor, Atlanta, GA 30322, USA. Electronic address: dkooby@emory.edu.
authors.forename: David A
authors.initials: DA
authors.lastname: Kooby
mesh_terms: D006801:Humans; D018358:Neuroendocrine Tumors / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D010190:Pancreatic Neoplasms / Q000150:complications / Q000175:diagnosis / Q000601:surgery*
keywords: Carcinoid; Gastrinoma; Hepatectomy; Insulinoma; Neuroendocrine tumor; Pancreatectomy; Pancreatic neoplasm