title: Advanced Imaging for Biopsy Guidance in Primary Brain Tumors.
abstract: Accurate glioma sampling is required for diagnosis and establishing eligibility for relevant clinical trials. MR-based perfusion and spectroscopy sequences supplement conventional MR in noninvasively predicting the areas of highest tumor grade for biopsy. We report the case of a patient with gliomatosis cerebri and multifocal patchy enhancement in whom the combination of advanced and conventional imaging attributes successfully guided a diagnostic biopsy.
authors.affiliation: Neurological Surgery, NewYork-Presbyterian/Weill Cornell Medical Center.
authors.forename: Nelson
authors.initials: N
authors.lastname: Moussazadeh
authors.affiliation: Radiology, Division of Neuroradiology, Weill Cornell Medical College.
authors.forename: Apostolos J
authors.initials: AJ
authors.lastname: Tsiouris
authors.affiliation: Neurological Surgery, Weill Cornell Medical College ; Neurological Surgery, NewYork-Presbyterian/Weill Cornell Medical Center.
authors.forename: Rohan
authors.initials: R
authors.lastname: Ramakrishna
keywords: glioma surgery; gliomatosis cerebri; image-guided therapy; magnetic resonance imaging; magnetic resonance spectroscopy; perfusion imaging