title: [EFFECT OF SYNTHETIC ANTIOXIADNT THIOPHAN AND SCUTELLARIA BAICALENSIS ROOT EXTRACT ON DRUG-INDUCED MUTAGENESIS].
abstract: Gene protective properties of synthetic antioxidant thiophane and the extract of in vitro cultivated roots of Scutellaria baicalensis were studied on the model of Dr. melanogaster larvae genetic structure damage by drugs cisplatin and cyclophosphan (cyclophosphamide). It is established that adding thiophane or Scutellaria baicalensis root extract to a nutrient medium leads to a decrease in amount of Dr. melanogaster recombinants (females bearing recessive yellow and/or singed marker mutations).
authors.forename: O V
authors.initials: OV
authors.lastname: Neupokoeva
authors.forename: O L
authors.initials: OL
authors.lastname: Voronova
authors.forename: A A
authors.initials: AA
authors.lastname: Churin
authors.forename: N I
authors.initials: NI
authors.lastname: Suslov
authors.forename: I V
authors.initials: IV
authors.lastname: Shilova
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002945:Cisplatin / Q000009:adverse effects / Q000494:pharmacology; D003520:Cyclophosphamide / Q000009:adverse effects / Q000494:pharmacology; D004331:Drosophila melanogaster; D016296:Mutagenesis / Q000187:drug effects*; D010936:Plant Extracts / Q000737:chemistry / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry*; D031364:Scutellaria baicalensis / Q000737:chemistry*; D013876:Thiophenes / Q000494:pharmacology*
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D013876:Thiophenes; C045141:thiophane; D003520:Cyclophosphamide; D002945:Cisplatin