title: Evaluation of autonomic nervous system function in children with overactive bladder syndrome.
abstract: We aimed to evaluate the autonomic nervous system activity in children with overactive bladder (OAB) syndrome.
  
  
  
  Included in the study were 40 children with overactive bladder and 28 healthy controls. Autonomic tests were performed on all participants, including heart rate interval variation (RRIV), heart rate response to valsalva maneuver, and sympathetic skin response (SSR).
  
  
  
  Mean valsalva rates in the overactive bladder and control groups were 1.53 ± 0.29 and 1.30 ± 0.18, respectively, a statistically significant difference (P < 0.001). Also significantly different were deep breathing RRIV values of the study and control groups: 56.65 ± 14.66 and 47.92 ± 10.15, respectively (P = 0.008). No statistical differences were found in SSR when OAB patients were compared with controls (P > 0.05).
  
  
  
  This study demonstrated a parasympathetic hyperactivity in children with OAB, results suggesting a dysfunction in their autonomic nervous systems. Neurourol. Urodynam. 36:673-676, 2017. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Faculty of Medicine, Department of Pediatrics, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Aysegul Dogan
authors.initials: AD
authors.lastname: Demir
authors.affiliation: Faculty of Medicine, Department of Neurology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Azize Esra
authors.initials: AE
authors.lastname: Gursoy
authors.affiliation: Faculty of Medicine, Department of Pediatric Cardiology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Goknar
authors.affiliation: Faculty of Medicine, Department of Pediatrics, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Selcuk
authors.initials: S
authors.lastname: Uzuner
authors.affiliation: Faculty of Medicine, Department of Pediatric Allergy and Immunology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Emin
authors.initials: E
authors.lastname: Ozkaya
authors.affiliation: Faculty of Medicine, Department of Pediatrics, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Ufuk
authors.initials: U
authors.lastname: Erenberk
authors.affiliation: Faculty of Medicine, Department of Pediatrics, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Aysel
authors.initials: A
authors.lastname: Vehapoglu
authors.affiliation: Faculty of Medicine, Department of Pediatrics, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Mehmet Rusen
authors.initials: MR
authors.lastname: Dundaroz
authors.affiliation: Faculty of Medicine, Department of Pediatric Cardiology, Bezmialem Vakif University, Istanbul, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Oktem
mesh_terms: D000293:Adolescent; D001341:Autonomic Nervous System / Q000503:physiopathology*; D002648:Child; D005260:Female; D005712:Galvanic Skin Response / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D006801:Humans; D008297:Male; D011930:Reaction Time / Q000502:physiology; D053201:Urinary Bladder, Overactive / Q000503:physiopathology*; D014636:Valsalva Maneuver
keywords: autonomic dysfunction; children; heart rate interval variation; overactive bladder