title: Course of illness in comorbid bipolar disorder and obsessive-compulsive disorder patients.
abstract: Psychiatric comorbidity is extremely common. One of the most common and difficult to manage comorbid conditions is the co-occurrence of bipolar disorder (BD) and obsessive compulsive disorder (OCD). We updated our recent systematic review searching the electronic databases MEDLINE, Embase, and PsycINFO to investigate course of illness in BD-OCD patients. We identified a total of 13 relevant papers which found that the majority of comorbid OCD cases appeared to be related to mood episodes. OC symptoms in comorbid patients appeared more often during depressive episodes, and comorbid BD and OCD cycled together, with OC symptoms often remitting during manic/hypomanic episodes.
authors.affiliation: Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy; Mood Disorders Program, Tufts Medical Center, Boston, MA, USA. Electronic address: andrea.amerio@studenti.unipr.it.
authors.forename: A
authors.initials: A
authors.lastname: Amerio
authors.affiliation: Department of Mental Health, Local Health Service, Parma, Italy. Electronic address: mtonna@ausl.pr.it.
authors.forename: M
authors.initials: M
authors.lastname: Tonna
authors.affiliation: Department of Biomedical, Biotechnological and Translational Sciences, Unit of Public Health, University of Parma, Parma, Italy. Electronic address: anna.odone@mail.harvard.edu.
authors.forename: A
authors.initials: A
authors.lastname: Odone
authors.affiliation: Institute of Psychiatry, Kings College London, London, UK. Electronic address: brendon.stubbs@kcl.ac.uk.
authors.forename: B
authors.initials: B
authors.lastname: Stubbs
authors.affiliation: Mood Disorders Program, Tufts Medical Center, Boston, MA, USA; Tufts University Medical School, Department of Psychiatry and Pharmacology, Boston, MA, USA. Electronic address: nghaemi@tuftsmedicalcenter.org.
authors.forename: S N
authors.initials: SN
authors.lastname: Ghaemi
mesh_terms: D001714:Bipolar Disorder / Q000453:epidemiology / Q000503:physiopathology*; D015897:Comorbidity; D018450:Disease Progression; D006801:Humans; D009771:Obsessive-Compulsive Disorder / Q000453:epidemiology / Q000503:physiopathology*
keywords: Bipolar; Comorbidity; Course of illness; Obsessive–compulsive