title: An investigation of general predictors for cognitive-behavioural therapy outcome for anxiety disorders in a routine clinical setting.
abstract: BACKGROUND
  Cognitive-behavioural therapy (CBT) is effective for treating anxiety disorders and is offered in most mental health services around the world. However, a relatively large number of patients with anxiety disorders do not benefit from CBT, experience relapses or drop out. Reliable predictors of treatment effects are lacking. The aim of this study is to investigate the predictive value of emotion regulation and attentional control for CBT outcome in a routine setting.
  
  
  METHODS
  In this prospective and practice-based study, 112 patients with anxiety disorders referred for manual-based group CBT at two psychiatric outpatient clinics will be recruited. Emotion regulation, severity of anxiety and attentional control will be assessed with self-report measures and with an experimental computer-based attentional control task at baseline, post-treatment and at a 6-month follow-up. Emotion regulation will be measured with Difficulties in Emotion Regulation Questionnaire, severity of anxiety will be assessed with Beck Anxiety Inventory and attentional control will be measured with the self-report questionnaire, Attention Control Scale, and with an experimental computer-based attentional control task based on theory of visual attention. Data will be analysed using multilevel mixed-effects modelling.
  
  
  BACKGROUND
  The study is approved by the Danish National Ethical Board, the Department of Psychology Ethical Board, University of Copenhagen and by the Danish Data Protection Agency. Study findings will be disseminated through peer-reviewed journal publications and conference presentations. The Danish Committee System on Health Research Ethics has been notified about the project.
  
  
  BACKGROUND
  NCT02638363.
authors.affiliation: Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Sara Kerstine Kaya
authors.initials: SK
authors.lastname: Nielsen
authors.affiliation: Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Signe
authors.initials: S
authors.lastname: Vangkilde
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences Semel Institute, University of California, California, USA.
authors.forename: Kate B
authors.initials: KB
authors.lastname: Wolitzky-Taylor
authors.affiliation: Department of Psychology, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Sarah Ingrid Franksdatter
authors.initials: SI
authors.lastname: Daniel
authors.affiliation: Psychiatric Centre Copenhagen, Copenhagen University Hospital, Copenhagen, Denmark.
authors.forename: Ida
authors.initials: I
authors.lastname: Hageman
mesh_terms: D000293:Adolescent; D000328:Adult; D001008:Anxiety Disorders / Q000628:therapy*; D003071:Cognition; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D003718:Denmark; D004644:Emotions; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D012107:Research Design; D057566:Self Report; D012720:Severity of Illness Index; D016896:Treatment Outcome; D055815:Young Adult
keywords: MENTAL HEALTH