title: Wavefront Derived Refraction and Full Eye Biometry in Pseudophakic Eyes.
abstract: OBJECTIVE
  To assess wavefront derived refraction and full eye biometry including ciliary muscle dimension and full eye axial geometry in pseudophakic eyes using spectral domain OCT equipped with a Shack-Hartmann wavefront sensor.
  
  
  METHODS
  Twenty-eight adult subjects (32 pseudophakic eyes) having recently undergone cataract surgery were enrolled in this study. A custom system combining two optical coherence tomography systems with a Shack-Hartmann wavefront sensor was constructed to image and monitor changes in whole eye biometry, the ciliary muscle and ocular aberration in the pseudophakic eye. A Badal optical channel and a visual target aligning with the wavefront sensor were incorporated into the system for measuring the wavefront-derived refraction. The imaging acquisition was performed twice. The coefficients of repeatability (CoR) and intraclass correlation coefficient (ICC) were calculated.
  
  
  RESULTS
  Images were acquired and processed successfully in all patients. No significant difference was detected between repeated measurements of ciliary muscle dimension, full-eye biometry or defocus aberration. The CoR of full-eye biometry ranged from 0.36% to 3.04% and the ICC ranged from 0.981 to 0.999. The CoR for ciliary muscle dimensions ranged from 12.2% to 41.6% and the ICC ranged from 0.767 to 0.919. The defocus aberrations of the two measurements were 0.443 ± 0.534 D and 0.447 ± 0.586 D and the ICC was 0.951.
  
  
  CONCLUSIONS
  The combined system is capable of measuring full eye biometry and refraction with good repeatability. The system is suitable for future investigation of pseudoaccommodation in the pseudophakic eye.
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.|Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States of America.
authors.forename: Xinjie
authors.initials: X
authors.lastname: Mao
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States of America.
authors.forename: James T
authors.initials: JT
authors.lastname: Banta
authors.affiliation: School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, China.|Department of Ophthalmology, Shanghai First People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
authors.forename: Bilian
authors.initials: B
authors.lastname: Ke
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States of America.
authors.forename: Hong
authors.initials: H
authors.lastname: Jiang
authors.affiliation: New England College of Optometry, Boston, Massachusetts, United States of America.
authors.forename: Jichang
authors.initials: J
authors.lastname: He
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States of America.
authors.forename: Che
authors.initials: C
authors.lastname: Liu
authors.affiliation: Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, United States of America.
authors.forename: Jianhua
authors.initials: J
authors.lastname: Wang
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001699:Biometry; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019591:Pseudophakia / Q000473:pathology*; D041623:Tomography, Optical Coherence