title: Performance of three large-volume infusion pumps with the monoplace hyperbaric chamber.
abstract: We evaluated the Zyno Medical Z-800F, CME Body Guard 323 Color Vision, and Baxter Flo-Gard 6201 infusion pumps for monoplace chamber conditions. We adjusted pump occlusion pressure allowing infusion to 3 atmospheres absolute (atm abs). Baxter and Zyno pumps were connected to the chamber pass-through with rigid small-bore tubing. The CME infusion set was connected directly to the pass-through. We infused saline to a collection manifold inside a monoplace chamber at 1-100 mL/ hour under pressures ranging from 0.85-3.0 atm abs. We averaged results from three to five separate tests for each condition. At baseline, pumps performed within ±10% of expected (our measurement capability). However, clinical engineering verified performance within manufacturer specifications (±5% at atmospheric pressure). During a carbon monoxide hyperbaric protocol (3 atm abs/2 atm abs), measured flow with the Baxter, CME and Zyno pumps was ±5% of setting at 10 mL/hour (95%, 103%, 95%, respectively); at 1 mL/hour, average flow were 91%, 83%, 83%, respectively. During timed testing (volume recorded before decompression), pump accuracy was ±10% at 10 and 100 mL/hour. Tubing compliance compromised performance at lower flow rates, magnified by increased pressure. These pumps have potential for monoplace chamber use, although not supported by the manufacturers or FDA-cleared. At low flow rates, tubing compliance affects delivered volumes.
authors.forename: James
authors.initials: J
authors.lastname: Bell
authors.forename: Lindell K
authors.initials: LK
authors.lastname: Weaver
authors.forename: Kayla
authors.initials: K
authors.lastname: Deru
mesh_terms: D001274:Atmospheric Pressure; D018795:Device Approval; D004867:Equipment Design; D005069:Evaluation Studies as Topic; D006931:Hyperbaric Oxygenation / Q000295:instrumentation*; D007260:Infusion Pumps / Q000592:standards*; D007262:Infusions, Intravenous / Q000295:instrumentation*; D008422:Materials Testing / Q000379:methods*; D012015:Reference Standards; D012965:Sodium Chloride / Q000008:administration & dosage
chemical_list: D012965:Sodium Chloride