title: Translational Control: Selective Upregulation of ECM Components Drives Tumour Growth.
abstract: A new mechanistic link has been identified between the expression of initiator methionine tRNA and cancer progression, whereby elevated levels of this tRNA specifically drive synthesis of secretome components, resulting in a type II collagen-rich matrix that promotes tumour progression.
authors.affiliation: MRC Toxicology Unit, Lancaster Rd, Leicester LE1 9HN, UK. Electronic address: aew5@leicester.ac.uk.
authors.forename: Anne E
authors.initials: AE
authors.lastname: Willis
mesh_terms: D006801:Humans; D009369:Neoplasms; D015533:Transcriptional Activation; D015854:Up-Regulation