title: Detection and monitoring of human bocavirus 1 infection by a new rapid antigen test.
abstract: Clinically relevant diagnosis of human bocavirus 1 (HBoV1) is challenging, as the virus is frequently detected in asymptomatic patients, and cofindings with other respiratory viruses are common. The clinical value of current diagnostic methods, such as PCR, is therefore low, and alternative diagnostic strategies are needed. We describe for the first time the use of an antigen detection assay for the rapid identification of HBoV1 in a paediatric patient with respiratory tract infection symptoms. We estimate the duration of active HBoV1 infection to be 6 days.
authors.affiliation: Department of Pediatric Infectious Diseases, Emma Children's Hospital, Academic Medical Center, Amsterdam, The Netherlands.
authors.forename: A H L
authors.initials: AH
authors.lastname: Bruning
authors.affiliation: Department of Virology, University of Turku and Biomaterials and Diagnostics Group, Turku University of Applied Sciences, Turku, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Susi
authors.affiliation: ArcDia International Oy Ltd., Turku, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Toivola
authors.affiliation: Trondheim University Hospital and Norwegian University of Science and Technology, Trondheim, Norway.
authors.forename: A
authors.initials: A
authors.lastname: Christensen
authors.affiliation: Department of Virology, University of Helsinki, and Helsinki University Hospital, Helsinki, Finland.
authors.forename: M
authors.initials: M
authors.lastname: Söderlund-Venermo
authors.affiliation: Department of Virology, University of Helsinki, and Helsinki University Hospital, Helsinki, Finland.
authors.forename: K
authors.initials: K
authors.lastname: Hedman
authors.affiliation: ArcDia International Oy Ltd., Turku, Finland.
authors.forename: H
authors.initials: H
authors.lastname: Aatola
authors.affiliation: Department of Immunology and Cell Biology, Institute of Biotechnology, Vilnius University, Lithuania.
authors.forename: A
authors.initials: A
authors.lastname: Zvirbliene
authors.affiliation: ArcDia International Oy Ltd., Turku, Finland.
authors.forename: J O
authors.initials: JO
authors.lastname: Koskinen
keywords: Human bocavirus; human bocavirus 1; point-of-care test; rapid antigen detection assay; respiratory infection