title: Chiral Phosphorus-Olefin Ligands for the Rh(I) -Catalyzed Asymmetric Addition of Aryl Boronic Acids to Electron-Deficient Olefins.
abstract: New chiral phosphorus-olefin hybrid ligands derived from the rigid "privileged" l-proline have been conveniently prepared and applied in the rhodium-catalyzed asymmetric arylation of electron-deficient olefins with arylboronic acids at room temperature; this reaction provides the desired products in excellent yields and high enantioselectivities. The origin of observed stereoselectivity has been investigated by density functional theory (DFT) calculations.
authors.affiliation: State Key Lab of Urban Water Resource and Environment (SKLUWRE), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, China. chenqian@hit.edu.cn.
authors.forename: Qian
authors.initials: Q
authors.lastname: Chen
authors.affiliation: State Key Lab of Urban Water Resource and Environment (SKLUWRE), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Li
authors.affiliation: State Key Laboratory of Fine Chemicals, School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian, 116024, China.
authors.forename: Guangli
authors.initials: G
authors.lastname: Zhou
authors.affiliation: State Key Lab of Urban Water Resource and Environment (SKLUWRE), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, China.
authors.forename: Xiaoli
authors.initials: X
authors.lastname: Ma
authors.affiliation: State Key Lab of Urban Water Resource and Environment (SKLUWRE), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Zhang
authors.affiliation: State Key Lab of Urban Water Resource and Environment (SKLUWRE), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, China.
authors.forename: Fang
authors.initials: F
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Fine Chemicals, School of Pharmaceutical Science and Technology, Dalian University of Technology, Dalian, 116024, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Luo
authors.affiliation: State Key Lab of Urban Water Resource and Environment (SKLUWRE), School of Chemistry and Chemical Engineering, Harbin Institute of Technology, Harbin, Heilongjiang, 150080, China.
authors.forename: Wujiong
authors.initials: W
authors.lastname: Xia
mesh_terms: D001555:Benzene Derivatives / Q000138:chemical synthesis* / Q000737:chemistry; D001897:Boronic Acids / Q000737:chemistry*; D002384:Catalysis; D053138:Cyclohexenes / Q000737:chemistry*; D008024:Ligands; D009943:Organophosphorus Compounds / Q000737:chemistry*; D011759:Pyrrolidines / Q000737:chemistry; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D001555:Benzene Derivatives; D001897:Boronic Acids; D053138:Cyclohexenes; D008024:Ligands; D009943:Organophosphorus Compounds; D011759:Pyrrolidines; D012428:Ruthenium
keywords: L-proline; asymmetric arylation; electron-deficient olefins; ligands; rhodium