title: Biomaterials for hollow organ tissue engineering.
abstract: Tissue engineering is a rapidly advancing field that is likely to transform how medicine is practised in the near future. For hollow organs such as those found in the cardiovascular and respiratory systems or gastrointestinal tract, tissue engineering can provide replacement of the entire organ or provide restoration of function to specific regions. Larger tissue-engineered constructs often require biomaterial-based scaffold structures to provide support and structure for new tissue growth. Consideration must be given to the choice of material and manufacturing process to ensure the de novo tissue closely matches the mechanical and physiological properties of the native tissue. This review will discuss some of the approaches taken to date for fabricating hollow organ scaffolds and the selection of appropriate biomaterials.
authors.affiliation: Applied Biomedical Engineering Group, Division of Medicine, University College London, 21 University Street, London, UK.
authors.forename: Eseelle K
authors.initials: EK
authors.lastname: Hendow
authors.affiliation: Applied Biomedical Engineering Group, Division of Medicine, University College London, 21 University Street, London, UK.
authors.forename: Pauline
authors.initials: P
authors.lastname: Guhmann
authors.affiliation: Applied Biomedical Engineering Group, Division of Medicine, University College London, 21 University Street, London, UK.
authors.forename: Bernice
authors.initials: B
authors.lastname: Wright
authors.affiliation: Applied Biomedical Engineering Group, Division of Medicine, University College London, 21 University Street, London, UK.
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Sofokleous
authors.affiliation: Applied Biomedical Engineering Group, Division of Medicine, University College London, 21 University Street, London, UK.
authors.forename: Nina
authors.initials: N
authors.lastname: Parmar
authors.affiliation: Applied Biomedical Engineering Group, Division of Medicine, University College London, 21 University Street, London, UK.
authors.forename: Richard M
authors.initials: RM
authors.lastname: Day
keywords: Biocompatible; Biomaterials; Regenerative medicine; Scaffold; Tissue engineering