title: Tuning the nitric oxide release from CPO-27 MOFs.
abstract: Nitric oxide (NO) storage and release measurements have been recorded for Ni-doped CPO-27 (Mg) and CPO-27 (Zn), and the biological effect of the released NO was assessed in porcine coronary artery relaxation tests. The results indicate that the doping strategy leads to increased levels of NO storage and delivery compared to the parent materials and that the NO dosage and biological response can be tunedviathis approach to suit the requirements of particular applications.
authors.affiliation: School of Chemistry, University of St Andrews, St Andrews, Fife, KY16 9ST, Scotland, UK. Email: sjw9@st-andrews.ac.uk.
authors.forename: Damiano
authors.initials: D
authors.lastname: Cattaneo
authors.affiliation: School of Chemistry, University of St Andrews, St Andrews, Fife, KY16 9ST, Scotland, UK. Email: sjw9@st-andrews.ac.uk.
authors.forename: Stewart J
authors.initials: SJ
authors.lastname: Warrender
authors.affiliation: School of Chemistry, University of St Andrews, St Andrews, Fife, KY16 9ST, Scotland, UK. Email: sjw9@st-andrews.ac.uk.
authors.forename: Morven J
authors.initials: MJ
authors.lastname: Duncan
authors.affiliation: Department of Diabetes & Cardiovascular Science, University of the Highlands and Islands, Centre for Health Science, Inverness, IV2 3JH, Scotland, UK.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Kelsall
authors.affiliation: Department of Diabetes & Cardiovascular Science, University of the Highlands and Islands, Centre for Health Science, Inverness, IV2 3JH, Scotland, UK.
authors.forename: Mary K
authors.initials: MK
authors.lastname: Doherty
authors.affiliation: Department of Diabetes & Cardiovascular Science, University of the Highlands and Islands, Centre for Health Science, Inverness, IV2 3JH, Scotland, UK.
authors.forename: Phillip D
authors.initials: PD
authors.lastname: Whitfield
authors.affiliation: Department of Diabetes & Cardiovascular Science, University of the Highlands and Islands, Centre for Health Science, Inverness, IV2 3JH, Scotland, UK.
authors.forename: Ian L
authors.initials: IL
authors.lastname: Megson
authors.affiliation: School of Chemistry, University of St Andrews, St Andrews, Fife, KY16 9ST, Scotland, UK. Email: sjw9@st-andrews.ac.uk.
authors.forename: Russell E
authors.initials: RE
authors.lastname: Morris