title: The effect of the acceleration/deceleration trauma in angioid streaks: A pathogenic hypothesis.
abstract: METHODS
  A 59-year-old male with acceleration/deceleration cranial trauma (ADT), caused by a car accident. After one month, he presented with loss of visual acuity in the right eye. A fluorescein angiography test was performed and it detected centrifugal hyperfluorescent lines from the optic nerve head, a characteristic compatible with the diagnosis of angioid streaks. The loss of visual acuity was demonstrated by the discovery of a juxtafoveal choroidal neovascular membrane (CNV).
  
  
  CONCLUSIONS
  ADT can cause hyper-extension of the eyeball in its equator line, producing the rupture of fragile structures such as the Bruch membrane (MB) in patients with angioid streaks and the subsequent formation of CNV.
authors.affiliation: Oftalmología, Hospital General Universitario Gregorio Marañón, Instituto Provincial de Oftalmología, Madrid, España. Electronic address: Julia.fajardosanchez@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Fajardo Sánchez
authors.affiliation: Oftalmología, Hospital General Universitario Gregorio Marañón, Instituto Provincial de Oftalmología, Madrid, España.
authors.forename: C E
authors.initials: CE
authors.lastname: Chau Ramos
authors.affiliation: Oftalmología, Hospital General Universitario Gregorio Marañón, Instituto Provincial de Oftalmología, Madrid, España.
authors.forename: P J
authors.initials: PJ
authors.lastname: Mazagatos Used
authors.affiliation: Sección de Retina, Hospital General Universitario Gregorio Marañón, Instituto Provincial de Oftalmología, Madrid, España.
authors.forename: M J
authors.initials: MJ
authors.lastname: Aparicio Hernandez-Lastras
mesh_terms: D000054:Acceleration / Q000009:adverse effects*; D000063:Accidents, Traffic; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use; D000793:Angioid Streaks / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology; D000068258:Bevacizumab / Q000627:therapeutic use; D016570:Bruch Membrane / Q000293:injuries*; D020256:Choroidal Neovascularization / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000503:physiopathology; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D008875:Middle Aged; D060051:Occupational Injuries / Q000503:physiopathology*; D061848:Optical Imaging; D012422:Rupture, Spontaneous; D013314:Stress, Mechanical; D014911:Whiplash Injuries / Q000150:complications*
chemical_list: D020533:Angiogenesis Inhibitors; D000068258:Bevacizumab
keywords: Acceleration/deceleration trauma; Angiografía fluoresceínica; Angioid streaks; Anti-VEGF; Choroidal neovascularisation membrane; Estrías angioides; Fluorescein angiography; Membrana neovascular coroidea; Trauma por aceleración/desaceleración