title: A Geodesics-Based Surface Parameterization to Assess Aneurysm Progression.
abstract: Abdominal aortic aneurysm (AAA) intervention and surveillance is currently based on maximum transverse diameter, even though it is recognized that this might not be the best strategy. About 10% of patients with small AAA transverse diameters, for whom intervention is not considered, still rupture; while patients with large AAA transverse diameters, for whom intervention would have been recommended, have stable aneurysms that do not rupture. While maximum transverse diameter is easy to measure and track in clinical practice, one of its main drawbacks is that it does not represent the whole AAA and rupture seldom occurs in the region of maximum transverse diameter. By following maximum transverse diameter alone clinicians are missing information on the shape change dynamics of the AAA, and clues that could lead to better patient care. We propose here a method to register AAA surfaces that were obtained from the same patient at different time points. Our registration method could be used to track the local changes of the patient-specific AAA. To achieve registration, our procedure uses a consistent parameterization of the AAA surfaces followed by strain relaxation. The main assumption of our procedure is that growth of the AAA occurs in such a way that surface strains are smoothly distributed, while regions of small and large surface growth can be differentiated. The proposed methodology has the potential to unravel different patterns of AAA growth that could be used to stratify patient risks.
authors.forename: Ly
authors.initials: L
authors.lastname: Phan
authors.forename: Katherine
authors.initials: K
authors.lastname: Courchaine
authors.forename: Amir
authors.initials: A
authors.lastname: Azarbal
authors.forename: David
authors.initials: D
authors.lastname: Vorp
authors.forename: Cindy
authors.initials: C
authors.lastname: Grimm
authors.forename: Sandra
authors.initials: S
authors.lastname: Rugonyi
mesh_terms: D000818:Animals; D017544:Aortic Aneurysm, Abdominal / Q000175:diagnosis* / Q000000981:diagnostic imaging; D018450:Disease Progression; D042241:Early Diagnosis; D006801:Humans; D007091:Image Processing, Computer-Assisted; D013499:Surface Properties; D014057:Tomography, X-Ray Computed