title: [Pancreatic neuroendocrine neoplasms].
abstract: Pancreatic neuroendocrine neoplasms (NEN) account for 1-2% of all pancreatic neoplasms and represent a rare differential diagnosis. While some pancreatic NEN are hormonally active and exhibit endocrine activity associated with characteristic symptoms, the majority are hormonally inactive. Imaging techniques such as ultrasound, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) or as combined PET/CT play a crucial role in the initial diagnosis, therapy planning and control. Endoscopic ultrasound (EUS) and multiphase CT represent the reference methods for localization of the primary pancreatic tumor. Particularly in the evaluation of small liver lesions MRI is the method of choice. Somatostatin receptor scintigraphy and somatostatin receptor PET/CT are of particular value for whole body staging and special aspects of further therapy planning.
authors.affiliation: Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen, Hufelandstrasse 55, 45147, Essen, Deutschland. karsten.beiderwellen@uni-due.de.
authors.forename: K
authors.initials: K
authors.lastname: Beiderwellen
authors.affiliation: Klinik für Nuklearmedizin, Universitätsklinikum Essen, Hufelandstrasse 55, 45147, Essen, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Sabet
authors.affiliation: Institut für Diagnostische und Interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Essen, Hufelandstrasse 55, 45147, Essen, Deutschland.
authors.forename: T C
authors.initials: TC
authors.lastname: Lauenstein
authors.affiliation: Klinik für Endokrinologie und Stoffwechselerkrankungen, Universitätsklinikum Essen, Hufelandstrasse 55, 45147, Essen, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Lahner
authors.affiliation: Klinik für Nuklearmedizin, Universitätsklinikum Essen, Hufelandstrasse 55, 45147, Essen, Deutschland.
authors.forename: T D
authors.initials: TD
authors.lastname: Poeppel
mesh_terms: D019160:Endosonography / Q000379:methods*; D019317:Evidence-Based Medicine; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D057054:Molecular Imaging / Q000379:methods*; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging* / Q000628:therapy; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*
keywords: Magnetic resonance imaging; Neuroendocrine tumors; Positron emission tomography; Review; Ultrasound