title: Failure of primary atovaquone prophylaxis for prevention of toxoplasmosis in hematopoietic cell transplant recipients.
abstract: The efficacy of primary prophylaxis with atovaquone in preventing Toxoplasma reactivation and disease in hematopoietic cell transplant (HCT) recipients is unknown. We describe 2 cases of atovaquone prophylaxis failure in pre-HCT Toxoplasma-seropositive (pre-HCTSP) recipients who underwent allogeneic HCT (allo-HCT) and review the literature on atovaquone prophylaxis in HCT recipients.
authors.affiliation: Division of Infectious Diseases and Geographic Medicine, School of Medicine, Stanford University, Stanford, California, USA.
authors.forename: K
authors.initials: K
authors.lastname: Gajurel
authors.affiliation: Division of Infectious Diseases and Geographic Medicine, School of Medicine, Stanford University, Stanford, California, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Gomez
authors.affiliation: Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California, USA.
authors.forename: R
authors.initials: R
authors.lastname: Dhakal
authors.affiliation: Department of Pathology, School of Medicine, Stanford University, Stanford, California, USA.
authors.forename: H
authors.initials: H
authors.lastname: Vogel
authors.affiliation: Division of Infectious Diseases and Geographic Medicine, School of Medicine, Stanford University, Stanford, California, USA.|Toxoplasma Serology Laboratory, National Reference Center for the Study and Diagnosis of Toxoplasmosis, Palo Alto, California, USA.
authors.forename: J G
authors.initials: JG
authors.lastname: Montoya
keywords: 
  Toxoplasma
  ; atovaquone; hematopoietic cell transplant; preemptive treatment; prophylaxis; toxoplasmosis