title: [PCR study of the human herpes virus type 6 and other viruses of the herpes group in eye diseases].
abstract: To study the role of the HHV-6 type in the development of eye diseases PCR tests of blood (152), cornea biopsies (61), and intraocular fluids (11) for HHV-6 and other viruses of the herpes group (HSV type 1 and 2, CMV, EBV) were conducted. It was found that the HHV-6, along with other representatives of the Herpesviridae, can be detected in patients with different clinical forms of ophthalmopathology (174 patients were surveyed). Viral DNA was detected in blood, cornea, and in the anterior chamber fluid. The obtained data allow that the HHV-6 to be suggested as a possible cause of the ophthalmic herpes along with the other viruses of this group. It makes finding the virus DNA an essential step towards setting the etiologic diagnosis of the ophthalmological patients.
authors.forename: O S
authors.initials: OS
authors.lastname: Slepowa
authors.forename: E V
authors.initials: EV
authors.lastname: Svetlova
authors.forename: L A
authors.initials: LA
authors.lastname: Kovaleva
authors.forename: P V
authors.initials: PV
authors.lastname: Makarov
authors.forename: A E
authors.initials: AE
authors.lastname: Kugusheva
authors.forename: E V
authors.initials: EV
authors.lastname: Denisova
authors.forename: E S
authors.initials: ES
authors.lastname: Vahova
authors.forename: G Yu
authors.initials: GY
authors.lastname: Zaharova
authors.forename: Yu A
authors.initials: YA
authors.lastname: Kondrat'eva
authors.forename: A E
authors.initials: AE
authors.lastname: Andryushin
authors.forename: V V
authors.initials: VV
authors.lastname: Demkin
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000867:Anterior Chamber / Q000473:pathology / Q000821:virology; D001082:Aqueous Humor / Q000821:virology; D002648:Child; D002675:Child, Preschool; D003315:Cornea / Q000473:pathology / Q000821:virology; D003587:Cytomegalovirus / Q000235:genetics / Q000302:isolation & purification; D004279:DNA, Viral / Q000235:genetics*; D005128:Eye Diseases / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D005260:Female; D006566:Herpesviridae Infections / Q000175:diagnosis* / Q000473:pathology / Q000821:virology; D018259:Herpesvirus 1, Human / Q000235:genetics / Q000302:isolation & purification; D018258:Herpesvirus 2, Human / Q000235:genetics / Q000302:isolation & purification; D004854:Herpesvirus 4, Human / Q000235:genetics / Q000302:isolation & purification; D015654:Herpesvirus 6, Human / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D008297:Male; D008875:Middle Aged; D016133:Polymerase Chain Reaction
chemical_list: D004279:DNA, Viral