title: A cluster of salivirus A1 (Picornaviridae) infections in newborn babies with acute gastroenteritis in a neonatal hospital unit in Hungary.
abstract: Salivirus (family Picornaviridae) may be associated with acute gastroenteritis in humans, but there have been no reports of salivirus outbreaks. Salivirus A1 infection with faecal virus concentrations of 2.1-2.6 × 10(9)/g were identified retrospectively in newborn babies, between the ages of 1.5 and 5 days, with apparent clinical symptoms of diarrhea (100 %), fever (40 %), vomiting (40 %), and loss of appetite (40 %) in a neonatal hospital unit in Hungary in July 2013. The complete genome sequence of the salivirus (including the 5'-terminal end) was determined. Salivirus mono-infection may be associated with gastroenteritis in babies who are a few days old. Salivirus testing should be done in public health laboratories in gastroenteritis outbreaks with unknown etiology.
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Szabadság út 7, 7623, Pécs, Hungary.|University of Pécs, Pécs, Hungary.
authors.forename: Ákos
authors.initials: Á
authors.lastname: Boros
authors.affiliation: Department of Epidemiology, ÁNTSZ Regional Institute of State Public Health Service, Kecskemét, Hungary.
authors.forename: Margit
authors.initials: M
authors.lastname: Raáb
authors.affiliation: Department of Pediatrics, Neonatal Care Unit, Town Hospital of Baja, Baja, Hungary.
authors.forename: Éva
authors.initials: É
authors.lastname: Károly
authors.affiliation: Department of Pediatrics, Neonatal Care Unit, Town Hospital of Baja, Baja, Hungary.
authors.forename: Adrienn
authors.initials: A
authors.lastname: Karai
authors.affiliation: Laboratory of Virology, ÁNTSZ Regional Institute of State Public Health Service, Szeged, Hungary.
authors.forename: Andrea
authors.initials: A
authors.lastname: Kátai
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Szabadság út 7, 7623, Pécs, Hungary.|University of Pécs, Pécs, Hungary.
authors.forename: Nóra
authors.initials: N
authors.lastname: Bolba
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Szabadság út 7, 7623, Pécs, Hungary.|University of Pécs, Pécs, Hungary.
authors.forename: Péter
authors.initials: P
authors.lastname: Pankovics
authors.affiliation: Regional Laboratory of Virology, National Reference Laboratory of Gastroenteric Viruses, ÁNTSZ Regional Institute of State Public Health Service, Szabadság út 7, 7623, Pécs, Hungary. reuter.gabor@gmail.com.|University of Pécs, Pécs, Hungary. reuter.gabor@gmail.com.
authors.forename: Gábor
authors.initials: G
authors.lastname: Reuter
mesh_terms: D000208:Acute Disease; D004196:Disease Outbreaks; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology*; D016679:Genome, Viral; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D007231:Infant, Newborn; D017720:Molecular Epidemiology; D009690:Nucleic Acid Conformation; D009725:Nurseries, Hospital; D010802:Phylogeny; D010849:Picornaviridae / Q000235:genetics* / Q000302:isolation & purification / Q000472:pathogenicity; D010850:Picornaviridae Infections / Q000453:epidemiology* / Q000821:virology*; D012367:RNA, Viral / Q000737:chemistry / Q000235:genetics; D012189:Retrospective Studies
chemical_list: D012367:RNA, Viral