title: Age and education-matched cut-off scores for the revised German/Swiss-German version of ECAS.
abstract: The Edinburgh Cognitive and Behavioural ALS Screen (ECAS) has been developed to assess cognition and behaviour in patients with amyotrophic lateral sclerosis (ALS). Cognitive impairments of ALS-specific and ALS-non-specific functions can be determined using cut-off scores based on performance of healthy subjects. However, detailed analyses show that older healthy subjects perform worse than younger ones, whereas highly-educated individuals perform better than those with lower education levels. As a consequence, this study presents new age and education matched cut-off scores for the revised German/Swiss-German version of the ECAS based on the performance of 86 healthy subjects.
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Markus
authors.initials: M
authors.lastname: Loose
authors.affiliation: b Kantonsspital St. Gallen, Neuromuscular Disease Centre/ALS Clinic , Switzerland .
authors.forename: Christian
authors.initials: C
authors.lastname: Burkhardt
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Helena
authors.initials: H
authors.lastname: Aho-Özhan
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Jürgen
authors.initials: J
authors.lastname: Keller
authors.affiliation: c Department of Neurology , Hanover Medical School .|d Department of Neurology , Otto-von-Guericke University Magdeburg, Magdeburg, and German Centre for Neurodegenerative Diseases , Magdeburg , Germany , and.
authors.forename: Susanne
authors.initials: S
authors.lastname: Abdulla
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Sarah
authors.initials: S
authors.lastname: Böhm
authors.affiliation: c Department of Neurology , Hanover Medical School .
authors.forename: Katja
authors.initials: K
authors.lastname: Kollewe
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Ingo
authors.initials: I
authors.lastname: Uttner
authors.affiliation: e Psychology-PPLS, Euan MacDonald Centre for Motor Neuron Disease Research & Anne Rowling Regenerative Neurology Clinic, University of Edinburgh , UK.
authors.forename: Sharon
authors.initials: S
authors.lastname: Abrahams
authors.affiliation: c Department of Neurology , Hanover Medical School .
authors.forename: Susanne
authors.initials: S
authors.lastname: Petri
authors.affiliation: b Kantonsspital St. Gallen, Neuromuscular Disease Centre/ALS Clinic , Switzerland .
authors.forename: Markus
authors.initials: M
authors.lastname: Weber
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Albert C
authors.initials: AC
authors.lastname: Ludolph
authors.affiliation: a Department of Neurology , Ulm University , Germany .
authors.forename: Dorothée
authors.initials: D
authors.lastname: Lulé
mesh_terms: D000293:Adolescent; D000328:Adult; D000375:Aging; D000690:Amyotrophic Lateral Sclerosis / Q000150:complications*; D002648:Child; D003072:Cognition Disorders / Q000175:diagnosis* / Q000209:etiology*; D004522:Educational Status; D005260:Female; D005858:Germany; D006801:Humans; D008297:Male; D001523:Mental Disorders / Q000175:diagnosis / Q000209:etiology; D008875:Middle Aged; D009483:Neuropsychological Tests; D015203:Reproducibility of Results; D013557:Switzerland; D055815:Young Adult
keywords: ECAS; German; amyotrophic lateral sclerosis; cognition; cut-off; executive; stratified; validation