title: SEROPREVALENCE OF TOXOPLASMA GONDII INFECTION AMONG PATIENTS ADMITTED TO AL-ZAHRA HOSPITAL, ISFAHAN, IRAN.
abstract: BACKGROUND
  Toxoplasma gondii (T. gondii) infection is one of the most common parasitic infections among humans and other warm-blooded animals worldwide. The aim of this study was to evaluate toxoplasmosis status in patients admitted to Al-Zahra hospital, Isfahan, Iran.
  
  
  METHODS
  This cross-sectional study was conducted from October 2012 to January 2015. During this period, 716 patients referred to AI-Zahra hospital in Isfahan city, Iran, were studied to investigate the IgG and IgM antibodies against T. gondii using ELISA kit. The data were analysed by Chi-square and Fisher's exact tests. In addition, the relation of data with age and sex were also examined.
  
  
  RESULTS
  Among 716 patients, 21 patients (2.9%) had positive IgM and 288 patients (40.2%) had positive IgG titer against T. gondii. Data analysis by Chi-square and Fisher's exact tests revealed that there was no significant relationship between IgG titer and age (p > 0.05). Additionally, there was no relationship between IgM titer and age (p > 0.05). The data showed that there was no relationship between IgG and IgM antibody titer and sex (p > 0.05).
  
  
  CONCLUSIONS
  The prevalence of toxoplasmosis in Isfahan inhabitants seems fairly high but it can be concluded that the rate of seropositive patient is moderate comparing to other regions of country. Accordingly, the authors propose that all sensitive patients have to be tested for T. gondii antibody in order to prevent the consequences of disease.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Mohaghegh
authors.forename: Hajar
authors.initials: H
authors.lastname: Yazdani
authors.forename: Mahboobe
authors.initials: M
authors.lastname: Hadipour
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Namdar
authors.forename: Mehdi
authors.initials: M
authors.lastname: Azami
authors.forename: Hamed
authors.initials: H
authors.lastname: Kalani
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Mirzaei
authors.forename: Seyed Hossein
authors.initials: SH
authors.lastname: Hejazi
authors.forename: Mahmood
authors.initials: M
authors.lastname: Taghavi-Shahri
authors.forename: Mohsen
authors.initials: M
authors.lastname: Ghomashlooyan
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D000913:Antibodies, Protozoan / Q000276:immunology*; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006761:Hospitals; D006801:Humans; D007297:Inpatients; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D016036:Seroepidemiologic Studies; D014122:Toxoplasma / Q000276:immunology*; D014123:Toxoplasmosis / Q000453:epidemiology* / Q000276:immunology / Q000469:parasitology; D055815:Young Adult
chemical_list: D000913:Antibodies, Protozoan