title: COMPARATIVE MACROSCOPIC STUDY OF OSTEOCHONDRAL DEFECTS PRODUCED IN FEMURS OF RABBITS REPAIRED WITH BIOPOLYMER GEL CANE SUGAR.
abstract: OBJECTIVE
  To study the surface, coloring, consistency, continuity and healing of osteochondral defects produced in the femoral condyles of rabbits and filled with sugar cane biopolymer gel (SCBG), after 90, 120 and 180 days, and in comparison with a control group.
  
  
  METHODS
  Sixteen adult New Zealand white rabbits aged 6 to 7 months, weighing between 2 and 2.5 kg and without locomotor system abnormalities were studied. In all the animals, a defect was made in the femoral condyles of the right and left knees, measuring 3.2 mm in diameter and 4 mm in depth, using a trephine. The animals were divided into two groups: study group formed by the right knees, in which the medial and lateral condyles received implants of SCBG; and control group formed by the left knees, in which the medial and lateral condyles were allowed to heal naturally. The knees were assessed 90, 120 and 180 days after the operation. After the animals had been sacrificed, the anatomical specimens were resected and placed in Bouin's solution. They were then photographed with a Nikon Coolpix 5400(®) coupled to a Nikon SM2800(®) stereoscopic loupe, to analyze the surface, coloring, consistency, continuity and healing.
  
  
  RESULTS
  The results were evaluated using the chi-square test. There were no significant differences in the macroscopic assessments of healing between the study and control groups.
  
  
  CONCLUSIONS
  With regard to the surface, coloring, consistency, continuity and healing of the defects, the macroscopic appearance of the tissue repaired with SCBG was similar to that of the control group.
authors.affiliation: PhD. Professor in the Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Paulo Cezar Vidal Carneiro
authors.initials: PC
authors.lastname: de Albuquerque
authors.affiliation: PhD. Professor in the Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Saulo Monteiro
authors.initials: SM
authors.lastname: Dos Santos
authors.affiliation: PhD. Professor in the Department of Surgery, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: José Lamartine
authors.initials: JL
authors.lastname: de Andrade Aguiar
authors.affiliation: Professor in the Department of Pathology, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Nicodemus Pontes
authors.initials: NP
authors.lastname: Filho
authors.affiliation: Professor in the Department of Pathology, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Roberto José Vieira
authors.initials: RJ
authors.lastname: de Mello
authors.affiliation: Professor in the Department of Pathology, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Mariana Lúcia Correia Ramos
authors.initials: ML
authors.lastname: Costa
authors.affiliation: Medical Student at the Federal university of Pernambuco, Recife, PE, Brazil.
authors.forename: Clarissa Miranda Carneiro
authors.initials: CM
authors.lastname: de Albuquerque Olbertz
authors.affiliation: Medical Student at the Federal university of Pernambuco, Recife, PE, Brazil.
authors.forename: Tarciana Mendonça
authors.initials: TM
authors.lastname: de Souza Almeida
authors.affiliation: Assistant Professor in the Department of Accounting and Actuarial Sciences, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Alessandro Henrique
authors.initials: AH
authors.lastname: da Silva Santos
authors.affiliation: Neurosurgeon at Hospital das Clínicas, Federal University of Pernambuco, Recife, PE, Brazil.
authors.forename: Joacil Carlos
authors.initials: JC
authors.lastname: da Silva
keywords: Articular; Cartilage; Polymers; Rabbits; Sugar; Wound Healing