title: Caveolae and Caveolin-1 Integrate Reverse Cholesterol Transport and Inflammation in Atherosclerosis.
abstract: Lipid disorder and inflammation play critical roles in the development of atherosclerosis. Reverse cholesterol transport is a key event in lipid metabolism. Caveolae and caveolin-1 are in the center stage of cholesterol transportation and inflammation in macrophages. Here, we propose that reverse cholesterol transport and inflammation in atherosclerosis can be integrated by caveolae and caveolin-1.
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. lqin1011@126.com.
authors.forename: Li
authors.initials: L
authors.lastname: Qin
authors.affiliation: Department of Urology, The First Hospital of Hunan University of Chinese Medicine, Changsha 410208, China. Nzhu0116@126.com.
authors.forename: Neng
authors.initials: N
authors.lastname: Zhu
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. aobaoxue@126.com.
authors.forename: Bao-Xue
authors.initials: BX
authors.lastname: Ao
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. iriniliu@163.com.
authors.forename: Chan
authors.initials: C
authors.lastname: Liu
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. syndyx0808@163.com.
authors.forename: Ya-Ning
authors.initials: YN
authors.lastname: Shi
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. Cocoadu006@163.com.
authors.forename: Ke
authors.initials: K
authors.lastname: Du
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. jchen3@umc.edu.|Department of Pharmacology and Toxicology, University of Mississippi Medical Center, School of Medicine, Jackson, MS 39216, USA. jchen3@umc.edu.
authors.forename: Jian-Xiong
authors.initials: JX
authors.lastname: Chen
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. xlzheng@ucalgary.ca.|Department of Biochemistry &amp; Molecular Biology, the Libin Cardiovascular Institute of Alberta, University of Calgary, 3330 Hospital Drive NW, Calgary, AB T2N 4N1, Canada. xlzheng@ucalgary.ca.
authors.forename: Xi-Long
authors.initials: XL
authors.lastname: Zheng
authors.affiliation: School of Pharmacy, Hunan University of Chinese Medicine, Changsha 410208, China. dfliao66@aliyun.com.
authors.forename: Duan-Fang
authors.initials: DF
authors.lastname: Liao
mesh_terms: D000818:Animals; D050197:Atherosclerosis / Q000378:metabolism*; D001693:Biological Transport, Active; D021941:Caveolae / Q000378:metabolism*; D051242:Caveolin 1 / Q000378:metabolism*; D002784:Cholesterol / Q000378:metabolism*; D006801:Humans; D007249:Inflammation / Q000378:metabolism
chemical_list: D051242:Caveolin 1; D002784:Cholesterol
keywords: atherosclerosis; caveolae; caveolin-1; inflammation; reverse cholesterol transport