title: Chronological Endoscopic and Pathological Observations in Russell Body Duodenitis.
abstract: A 64-year-old man was found to have a nodule in his right lung. He also complained of nausea and abdominal pain during the clinical course. Esophagogastroduodenoscopy revealed a duodenal ulcer associated with severe stenosis and a suspicion of malignancy. However, three subsequent biopsies revealed no evidence of malignancy. The fourth biopsy showed scattered large eosinophilic cells with an eccentric nucleus, leading to a diagnosis of Russell body duodenitis (RBD). RBD is an extremely rare disease, and little is known about its etiology and clinical course. The pathogenesis of RBD is discussed based on our experience with this case.
authors.affiliation: Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Goto
authors.affiliation: Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Okamoto
authors.affiliation: Department of Gastroenterology and Hepatology, Hagi Civil Hospital, Hagi, Japan.
authors.forename: Masaharu
authors.initials: M
authors.lastname: Matsumoto
authors.affiliation: Department of General Medicine, Hagi Civil Hospital, Hagi, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Saito
authors.affiliation: Department of Gastroenterology and Hepatology, Kanmon Medical Center, Shimonoseki, Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Yanai
authors.affiliation: Department of Molecular Pathology, Yamaguchi University Graduate School of Medicine, Ube, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Itoh
authors.affiliation: Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Ube, Japan.
authors.forename: Isao
authors.initials: I
authors.lastname: Sakaida
keywords: Duodenal ulcer; Russell body; Russell body duodenitis