title: PROGRESSIVE SYRINGOHYDROMYELIA AND DEGENERATIVE AXONOPATHY IN A BOBCAT (LYNX RUFUS) FOLLOWING SURGICAL CORRECTION OF A CHIARI-LIKE MALFORMATION.
abstract: A 3-yr-old male captive bobcat (Lynx rufus) presented with chronic ataxia and right-sided head tilt. Magnetic resonance imaging (MRI) revealed cerebellar crowding and compression consistent with Chiari-like malformation. The clinical signs did not improve after surgical occipital craniectomy, and 2 mo postoperatively a second MRI showed hydromyelia and continued cerebellar compression. The bobcat was euthanized, and necropsy showed chronic focal cerebellar herniation and chronic multifocal atlanto-occipital joint osteophyte proliferation. Histology confirmed the presence of a thick fibrous membrane along the caudal aspect of the cerebellar vermis, suggestive of postoperative adhesions, and axonal degeneration of the cervical spinal cord, even in sections without a central canal lesion. These lesions appear to have been complications associated with surgical correction of the Chiari-like malformation.
authors.forename: Ryan
authors.initials: R
authors.lastname: Sadler
authors.forename: Juergen
authors.initials: J
authors.lastname: Schumacher
authors.forename: Edward
authors.initials: E
authors.lastname: Ramsay
authors.forename: Brynn
authors.initials: B
authors.lastname: McCleery
authors.forename: Katherine
authors.initials: K
authors.lastname: Baine
authors.forename: William
authors.initials: W
authors.lastname: Thomas
authors.forename: Michelle
authors.initials: M
authors.lastname: Nobrega-Lee
authors.forename: George A
authors.initials: GA
authors.lastname: Henry
authors.forename: Shelley J
authors.initials: SJ
authors.lastname: Newman
mesh_terms: D000818:Animals; D001139:Arnold-Chiari Malformation / Q000601:surgery / Q000662:veterinary*; D002526:Cerebellar Diseases / Q000473:pathology / Q000601:surgery / Q000662:veterinary*; D019299:Decompression, Surgical / Q000662:veterinary*; D046008:Lynx; D008297:Male; D013595:Syringomyelia / Q000473:pathology / Q000662:veterinary*
keywords: Chiari-like malformation; Lynx rufus; bobcat; syringohydromyelia