title: Recent advances in mycotoxins detection.
abstract: Mycotoxins contamination in both food and feed is inevitable. Mycotoxin toxicity in foodstuff can occur at very low concentrations necessitating early availability of sensitive and reliable methods for their detection. The present research thrust is towards the development of a user friendly biosensor for mycotoxin detection at both academic and industrial levels to replace conventional expensive chromatographic and ELISA techniques. This review critically analyzes the recent research trend towards the construction of immunosensor, aptasensor, enzymatic sensors and others for mycotoxin detection with a reference to label and label free methods, synthesis of new materials including nano dimension, and transuding techniques. Technological aspects in the development of biosensors for mycotoxin detection, current challenges and future prospects are also included to provide a overview and suggestions for future research directions.
authors.affiliation: Amity Institute of Nanotechnology, Amity University Uttar Pradesh, Noida, India. Electronic address: ruchikachauhan@hotmail.com.
authors.forename: Ruchika
authors.initials: R
authors.lastname: Chauhan
authors.affiliation: Department of Applied Chemistry & Polymer Technology, Delhi Technological University, Delhi 110042, India. Electronic address: jaimnnit@gmail.com.
authors.forename: Jay
authors.initials: J
authors.lastname: Singh
authors.affiliation: Amity Institute of Nanotechnology, Amity University Uttar Pradesh, Noida, India. Electronic address: tsachdev0430@gmail.com.
authors.forename: Tushar
authors.initials: T
authors.lastname: Sachdev
authors.affiliation: Amity Institute of Nanotechnology, Amity University Uttar Pradesh, Noida, India. Electronic address: basu002@yahoo.com.
authors.forename: T
authors.initials: T
authors.lastname: Basu
authors.affiliation: Department of Biotechnology, Delhi Technological University, Delhi, India. Electronic address: bansi.malhotra@gmail.com.
authors.forename: B D
authors.initials: BD
authors.lastname: Malhotra
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D005506:Food Contamination / Q000032:analysis*; D006801:Humans; D007118:Immunoassay / Q000295:instrumentation / Q000379:methods; D054802:Molecular Imprinting / Q000379:methods; D009183:Mycotoxins / Q000032:analysis*; D011108:Polymers / Q000737:chemistry
chemical_list: D052157:Aptamers, Nucleotide; D009183:Mycotoxins; D011108:Polymers
keywords: Aptamers; Enzymatic inhibition; Immunosensor; Molecularly imprinted polymers, mimotopes; Mycotoxins