title: Asymmetric preparation of polysubstituted cyclopentanes by synergistic Pd(0)/amine catalyzed formal [3+2] cycloadditions of vinyl cyclopropanes with enals.
abstract: We report herein a novel diastereo- and enantiocontrolled preparation of polysubstituted cyclopentanes by the formal [3+2] cycloadditions of vinyl cyclopropanes with enals. In constrast with previously developed strategies, our original approach is based on the synergistic merger of iminium/enamine organocatalysis with palladium(0) catalysis.
authors.affiliation: PSL Research University, Chimie ParisTech - CNRS, Institut de Recherche de Chimie Paris, Paris, 75005, France. virginie.vidal@chimie-paristech.fr veronique.michelet@chimie-paristech.fr maxime.vitale@chimie-paristech.fr.
authors.forename: Maxime
authors.initials: M
authors.lastname: Laugeois
authors.forename: Sudipta
authors.initials: S
authors.lastname: Ponra
authors.forename: Virginie
authors.initials: V
authors.lastname: Ratovelomanana-Vidal
authors.forename: Véronique
authors.initials: V
authors.lastname: Michelet
authors.forename: Maxime R
authors.initials: MR
authors.lastname: Vitale