title: [GOAL-DIRECTED FLUID THERAPY IN SEVERE CONCOMITANT TRAUMA].
abstract: METHODS
  We examined 78 patients with severe concomitant injury. Were evaluated the severity of the injury and indices of volumetric haemodynamic monitoring by PICCO. The retrospective comparison group consisted of 50 patients with severe concomitant injury who were treated in the ICU of Trauma Institution during 2009-2011.
  
  
  RESULTS
  In patients with severe concomitant injury goal-directed fluid therapy based on PICCO monitoring parameters increasing the volume of infusion on the second and third post-traumatic days by 45% and 24%, respectively (< 0.05). Infusion-related pulmonary complications in the study group patients were not recorded Goal-directed fluid therapy was one of the factors that made it possible to reduce patient's mortality 2.1 times on conditions that severity of the injury and the initial state were similar. Colloid (6% HES 200/0.5) infusion was associated with increases in rate of transient azotemia.
authors.forename: A K
authors.initials: AK
authors.lastname: Konkaev
authors.forename: E I
authors.initials: EI
authors.lastname: Gurbanova
authors.forename: Z N
authors.initials: ZN
authors.lastname: Mynbaeva
mesh_terms: D000328:Adult; D000368:Aged; D000077324:Crystalloid Solutions; D017707:Erythrocyte Transfusion / Q000379:methods; D005440:Fluid Therapy / Q000379:methods*; D006439:Hemodynamics; D006801:Humans; D007552:Isotonic Solutions / Q000008:administration & dosage; D008875:Middle Aged; D009104:Multiple Trauma / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D015532:Rehydration Solutions / Q000008:administration & dosage; D012121:Respiration, Artificial; D015599:Trauma Severity Indices; D016896:Treatment Outcome
chemical_list: D000077324:Crystalloid Solutions; D007552:Isotonic Solutions; D015532:Rehydration Solutions