title: [Correlation of occupational stress with serum levels of immunoglobulins and complement in police].
abstract: OBJECTIVE
  To investigate the correlation of occupational stress with the serum levels of immunoglobulins(IgG, IgM, and IgA) and complement(C3 and C4).
  
  
  METHODS
  In May 2011, convenience sampling and cluster sampling were used to select 225 policemen from a local police station as study subjects. A questionnaire was used to investigate demographic features and occupational stress, and the immunoturbidimetric assay was applied to measure the serum levels of IgG, IgM, IgA, and complement C3 and C4.
  
  
  RESULTS
  Positive affectivity was positively correlated with the concentration of IgG(r=0.084, P<0.01); positive affectivity, coping strategy, and sleep quality were positively correlated with the concentration of IgM(r= 0.146, 0.155, and 0.203, all P<0.05); negative affectivity was negatively correlated with the concentration of IgM(r=-0.185, P<0.05). Reward and sleep quality were positively correlated with the concentration of C3(r= 0.172 and 0.285, both P<0.05), and negative affectivity was negatively correlated with the concentration of C3 (r=-0.174, P<0.05); sleep quality was positively correlated with the concentration of C4(r= 0.173, P<0.05), and negative affectivity was negatively correlated with the concentration of C4(r=-0.164, P<0.05). The logistic regression analysis revealed that the risks for a reduced concentration of IgG in the groups with high scores of social support and positive affectivity were 0.460 and 0.495 times those in the groups with low scores, while the risk for a reduced concentration of IgM in the group with a high score of coping strategy was 0.482 times that in the group with a low score.
  
  
  CONCLUSIONS
  Occupational stress is correlated with the serum levels of immunoglobulins and complement.
authors.affiliation: Henan Provincial Institute of Occupational Health, Zhengzhou 450052, China.
authors.forename: H
authors.initials: H
authors.lastname: Wu
authors.forename: K Y
authors.initials: KY
authors.lastname: Jiang
authors.forename: W H
authors.initials: WH
authors.lastname: Zhou
authors.forename: G Z
authors.initials: GZ
authors.lastname: Gu
authors.forename: Y Y
authors.initials: YY
authors.lastname: Wu
authors.forename: S F
authors.initials: SF
authors.lastname: Yu
mesh_terms: D000223:Adaptation, Psychological; D003176:Complement C3; D003181:Complement C4; D006801:Humans; D007136:Immunoglobulins; D016495:Police; D012201:Reward; D012944:Social Support; D013315:Stress, Psychological; D011795:Surveys and Questionnaires
chemical_list: C038245:C3 protein, human; D003176:Complement C3; D003181:Complement C4; D007136:Immunoglobulins