title: Iyengar-Yoga Compared to Exercise as a Therapeutic Intervention during (Neo)adjuvant Therapy in Women with Stage I-III Breast Cancer: Health-Related Quality of Life, Mindfulness, Spirituality, Life Satisfaction, and Cancer-Related Fatigue.
abstract: This study aims to test the effects of yoga on health-related quality of life, life satisfaction, cancer-related fatigue, mindfulness, and spirituality compared to conventional therapeutic exercises during (neo)adjuvant cytotoxic and endocrine therapy in women with breast cancer. In a randomized controlled trial 92 women with breast cancer undergoing oncological treatment were randomly enrolled for a yoga intervention (YI) (n = 45) or for a physical exercise intervention (PEI) (n = 47). Measurements were obtained before (t 0) and after the intervention (t 1) as well as 3 months after finishing intervention (t 2) using standardized questionnaires. Life satisfaction and fatigue improved under PEI (p < 0.05) but not under YI (t 0 to t 2). Regarding quality of life (EORTC QLQ-C30) a direct effect (t 0 to t 1; p < 0.001) of YI was found on role and emotional functioning, while under PEI only emotional functioning improved. Significant improvements (p < 0.001) were observed at both t 1 and t 2 also for symptom scales in both groups: dyspnea, appetite loss, constipation, and diarrhea. There was no significant difference between therapies for none of the analyzed variables neither for t 1 nor for t 2. During chemotherapy, yoga was not seen as more helpful than conventional therapeutic exercises. This does not argue against its use in the recovery phase.
authors.affiliation: Institute of Integrative Medicine, University of Witten/Herdecke, Herdecke, 58313 Herdecke, Germany.
authors.forename: Désirée
authors.initials: D
authors.lastname: Lötzke
authors.affiliation: Institute of Integrative Medicine, University of Witten/Herdecke, Herdecke, 58313 Herdecke, Germany.
authors.forename: Florian
authors.initials: F
authors.lastname: Wiedemann
authors.affiliation: Institute of Integrative Medicine, University of Witten/Herdecke, Herdecke, 58313 Herdecke, Germany.
authors.forename: Daniela
authors.initials: D
authors.lastname: Rodrigues Recchia
authors.affiliation: Department of Psychology and Psychotherapy, University of Witten/Herdecke, Herdecke, 58448 Witten, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Ostermann
authors.affiliation: Praxis Gynäkologie Arabella, 81925 Munich, Germany.
authors.forename: Daniel
authors.initials: D
authors.lastname: Sattler
authors.affiliation: Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Ettl
authors.affiliation: Klinikum rechts der Isar, Technical University Munich, 81675 Munich, Germany.
authors.forename: Marion
authors.initials: M
authors.lastname: Kiechle
authors.affiliation: Institute of Integrative Medicine, University of Witten/Herdecke, Herdecke, 58313 Herdecke, Germany.
authors.forename: Arndt
authors.initials: A
authors.lastname: Büssing