title: Genetic Characterization of an Ancestral Strain of the Avian-Origin H3N2 Canine Influenza Virus Currently Circulating in East Asia.
abstract: H3N2 canine influenza virus emerged in South Korea in 2007 and subsequently spread to China and Thailand, causing epidemic or endemic respiratory diseases in dogs. Through intermammalian species transmission, the virus has also infected cats. However, no direct evidence of significant genetic evolution has been reported since its first emergence. Here, we describe in depth the genetic and molecular characteristics of the ancestral strain (i.e., the first virus isolate from South Korea) of the H3N2 canine influenza virus currently circulating in East Asia.
authors.affiliation: Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
authors.forename: Jeong-Ki
authors.initials: JK
authors.lastname: Kim
authors.affiliation: Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
authors.forename: Jeong-Hyun
authors.initials: JH
authors.lastname: Nam
authors.affiliation: Korea Zoonosis Research Institute, Chonbuk National University, Iksan 54531, Republic of Korea.
authors.forename: Kwang-Soo
authors.initials: KS
authors.lastname: Lyoo
authors.affiliation: Research Unit, Green Cross Veterinary Products, Yongin 17066, Republic of Korea.
authors.forename: Hyoungjoon
authors.initials: H
authors.lastname: Moon
authors.affiliation: Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
authors.forename: Woonsung
authors.initials: W
authors.lastname: Na
authors.affiliation: Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
authors.forename: Eun-Jung
authors.initials: EJ
authors.lastname: Song
authors.affiliation: Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
authors.forename: Minjoo
authors.initials: M
authors.lastname: Yeom
authors.affiliation: Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
authors.forename: Sang-Mu
authors.initials: SM
authors.lastname: Shim
authors.affiliation: Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Republic of Korea.
authors.forename: Dae Gwin
authors.initials: DG
authors.lastname: Jeong
authors.affiliation: Animal and Plant Quarantine Agency, Gimcheon 39660, Republic of Korea.
authors.forename: Dong-Jun
authors.initials: DJ
authors.lastname: An
authors.affiliation: Research Unit, Green Cross Veterinary Products, Yongin 17066, Republic of Korea.
authors.forename: Bo-Kyu
authors.initials: BK
authors.lastname: Kang
authors.affiliation: Department of Pharmacy, College of Pharmacy, Korea University, Sejong 30019, Republic of Korea.
authors.forename: Daesub
authors.initials: D
authors.lastname: Song
mesh_terms: D000818:Animals; D002415:Cats / Q000821:virology; D002681:China / Q000453:epidemiology; D004283:Dog Diseases / Q000821:virology; D004285:Dogs / Q000821:virology; D019143:Evolution, Molecular; D005838:Genotype; D053122:Influenza A Virus, H3N2 Subtype / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D009976:Orthomyxoviridae Infections / Q000635:transmission / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D056910:Republic of Korea / Q000453:epidemiology; D017422:Sequence Analysis, DNA; D013785:Thailand / Q000453:epidemiology
keywords: Canine influenza virus; Cats; Companion animals; Dogs