title: [Infantile cortical hyperostosis: Case report].
abstract: Infantile Cortical Hyperostosis, or Caffey-Silverman disease, is a rare condition characterised by generalised bone proliferation mediated by an acute inflammatory process. Diagnosis can be made through clinical evaluation and X-ray studies. The course is generally self-limiting and prognosis is excellent.
  
  
  OBJECTIVE
  To present the case of a 4-month child with clinical and radiological symptoms compatible with Infantile Cortical Hyperostosis.
  
  
  METHODS
  A 4-month old male who presented with crying and irritability associated with swelling of the face, arms and legs was admitted to the Emergency Room of National Institute of Pediatrics. Bilateral mandibular swelling extending to periauricular region was observed, with no signs of inflammation. X-ray studies showed a periosteal reaction in the jaw, left femur and tibia, and radius bilateral. Clinical observation combined with analgesics and antipyretics was the only medical intervention. Four to six months after discharge from hospital, the symptoms disappeared, confirming the good prognosis of this condition.
  
  
  CONCLUSIONS
  Infantile cortical hyperostosis is a collagenopathy, which must be considered as a differential diagnosis in acute bone inflammatory processes, irritability and fever. It is important to understand and identify this disease and clinical-radiological correlation is remarkable.
authors.affiliation: Residencia Pediatría Médica, Instituto Nacional de Pediatría, Ciudad de México, México. Electronic address: mon.medley@gmail.com.
authors.forename: Mónica
authors.initials: M
authors.lastname: Rodríguez
authors.affiliation: Residencia Pediatría Médica, Instituto Nacional de Pediatría, Ciudad de México, México.
authors.forename: Luz Elena
authors.initials: LE
authors.lastname: Martínez
authors.affiliation: Servicio Ortopedia Pediátrica, Instituto Nacional de Pediatría, Ciudad de México, México.
authors.forename: José
authors.initials: J
authors.lastname: Cortés
authors.affiliation: Servicio Radiología Pediátrica, Instituto Nacional de Pediatría, Ciudad de México, México.
authors.forename: Armando
authors.initials: A
authors.lastname: de Uña
authors.affiliation: Residencia Urgencias Pediátricas, Instituto Nacional de Pediatría, Ciudad de México, México.
authors.forename: Valentina
authors.initials: V
authors.lastname: Vega
authors.affiliation: Servicio Urgencias Pediátricas, Instituto Nacional de Pediatría, Ciudad de México, México.
authors.forename: Mario
authors.initials: M
authors.lastname: Acosta
mesh_terms: D000700:Analgesics / Q000008:administration & dosage*; D058633:Antipyretics / Q000008:administration & dosage*; D003937:Diagnosis, Differential; D005334:Fever / Q000209:etiology; D006801:Humans; D006958:Hyperostosis, Cortical, Congenital / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D007223:Infant; D008297:Male; D011379:Prognosis
chemical_list: D000700:Analgesics; D058633:Antipyretics
keywords: Collagen; Colágeno; Cortical hyperostosis; Hiperostosis cortical; Inflamación; Inflammation; Periostio; Periostium