title: Marine Metabolites Modulating CB Receptors and TRP Channels.
abstract: Transient receptor potential channels and cannabinoid receptors are deputed to the regulation of sensory, homeostatic, and inflammatory events in the human organism. Therefore, their modulation promises to have relevant applications in important therapeutic areas such as inflammation, pain, and cancer. This review summarizes the contribution of marine research in this relatively young field, highlighting the potential of the chemodiversity carried by marine natural products in the discovery of new ligands.
authors.affiliation: Department of Pharmacy, University of Naples Federico II, Naples, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Rigano
authors.affiliation: Department of Pharmacy, University of Naples Federico II, Naples, Italy.
authors.forename: Carmen
authors.initials: C
authors.lastname: Formisano
authors.affiliation: Department of Pharmacy, University of Naples Federico II, Naples, Italy.
authors.forename: Orazio
authors.initials: O
authors.lastname: Taglialatela-Scafati
mesh_terms: D000818:Animals; D037421:Anthozoa / Q000737:chemistry; D059001:Aquatic Organisms; D001688:Biological Products / Q000494:pharmacology*; D000458:Cyanobacteria / Q000737:chemistry; D005658:Fungi / Q000737:chemistry; D006801:Humans; D011161:Porifera / Q000737:chemistry; D043882:Receptors, Cannabinoid / Q000187:drug effects*; D050051:Transient Receptor Potential Channels / Q000187:drug effects*
chemical_list: D001688:Biological Products; D043882:Receptors, Cannabinoid; D050051:Transient Receptor Potential Channels