title: MetaboLights: An Open-Access Database Repository for Metabolomics Data.
abstract: MetaboLights is the first general purpose, open-access database repository for cross-platform and cross-species metabolomics research at the European Bioinformatics Institute (EMBL-EBI). Based upon the open-source ISA framework, MetaboLights provides Metabolomics Standard Initiative (MSI) compliant metadata and raw experimental data associated with metabolomics experiments. Users can upload their study datasets into the MetaboLights Repository. These studies are then automatically assigned a stable and unique identifier (e.g., MTBLS1) that can be used for publication reference. The MetaboLights Reference Layer associates metabolites with metabolomics studies in the archive and is extensively annotated with data fields such as structural and chemical information, NMR and MS spectra, target species, metabolic pathways, and reactions. The database is manually curated with no specific release schedules. MetaboLights is also recommended by journals for metabolomics data deposition. This unit provides a guide to using MetaboLights, downloading experimental data, and depositing metabolomics datasets using user-friendly submission tools.
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Namrata S
authors.initials: NS
authors.lastname: Kale
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Haug
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Pablo
authors.initials: P
authors.lastname: Conesa
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Kalaivani
authors.initials: K
authors.lastname: Jayseelan
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Pablo
authors.initials: P
authors.lastname: Moreno
authors.affiliation: Oxford e-Research Centre, University of Oxford, Oxford, United Kingdom.
authors.forename: Philippe
authors.initials: P
authors.lastname: Rocca-Serra
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Venkata Chandrasekhar
authors.initials: VC
authors.lastname: Nainala
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Rachel A
authors.initials: RA
authors.lastname: Spicer
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Mark
authors.initials: M
authors.lastname: Williams
authors.affiliation: MRC HNR, Elsie Widdowson Laboratory, Cambridge, United Kingdom.
authors.forename: Xuefei
authors.initials: X
authors.lastname: Li
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Reza M
authors.initials: RM
authors.lastname: Salek
authors.affiliation: MRC HNR, Elsie Widdowson Laboratory, Cambridge, United Kingdom.
authors.forename: Julian L
authors.initials: JL
authors.lastname: Griffin
authors.affiliation: European Bioinformatics Institute (EMBL-EBI), European Molecular Biology Laboratory, Wellcome Trust Genome Campus, Hinxton, United Kingdom.
authors.forename: Christoph
authors.initials: C
authors.lastname: Steinbeck
mesh_terms: D022126:Access to Information; D016208:Databases, Factual; D055432:Metabolomics / Q000379:methods*; D057386:Search Engine
keywords: cross-platform; cross-species; metabolites; metabolomics; metadata; open-access; raw data