title: Usefulness of the fast spin-echo three-point Dixon (mDixon) image of the knee joint on 3.0-T MRI: comparison with conventional fast spin-echo T2 weighted image.
abstract: OBJECTIVE
  To compare the quality of two different imaging methods, three-point Dixon (mDixon) and fast spin-echo (FSE) T2 weighted image (T2WI) [and fat suppression (FS) T2WI], and to assess the utility of mDixon for the imaging of knee joint pathology.
  
  
  METHODS
  This retrospective study included 66 patients who underwent both mDixon and FSE T2WI (and FS T2WI) of the knee joint. Signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of the two sequences at the articular cartilage and ligament were measured. Two radiologists independently evaluated the anatomic identification score and diagnostic performances of the two sequences.
  
  
  RESULTS
  The mean SNRs and CNRs of the patellar cartilage, femoral cartilage and anterior cruciate ligament (ACL) were significantly higher on T2WI and FS T2WI than on mDixon imaging, with the exception of the mean SNR of ACL on in-phase images. Most of the anatomic identification scores did not show significant differences, except for inferiorities of the in-phase mDixon in the evaluation of the cruciate ligament. There were no significant differences in sensitivity, specificity and accuracy between mDixon and T2WI regarding diagnostic performance.
  
  
  CONCLUSIONS
  mDixon images have equivalent anatomic identification ability with the exception of cruciate ligament delineation on in-phase images and have a diagnostic performance comparable with that of FSE T2WI for meniscal, cartilage and ligament injuries of the knee joint. There would be a net saving in time, if mDixon was the only sequence used.
  
  
  CONCLUSIONS
  The mDixon images have equivalent anatomic identification abilities, with the exception of cruciate ligament delineation on in-phase images and have a diagnostic performance comparable with that of FSE T2WI for meniscal, cartilage and ligament injuries of the knee joint.
authors.affiliation: 1 Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
authors.forename: Hee J
authors.initials: HJ
authors.lastname: Park
authors.affiliation: 1 Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
authors.forename: So Y
authors.initials: SY
authors.lastname: Lee
authors.affiliation: 1 Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
authors.forename: Myung H
authors.initials: MH
authors.lastname: Rho
authors.affiliation: 1 Department of Radiology, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
authors.forename: Eun C
authors.initials: EC
authors.lastname: Chung
authors.affiliation: 2 Department of Orthopaedic Surgery, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
authors.forename: Jin H
authors.initials: JH
authors.lastname: Ahn
authors.affiliation: 2 Department of Orthopaedic Surgery, Sungkyunkwan University School of Medicine, Kangbuk Samsung Hospital, Seoul, Republic of Korea.
authors.forename: Jai H
authors.initials: JH
authors.lastname: Park
authors.affiliation: 3 Department of Radiology, Pusan National University Hospital, Busan, Republic of Korea.
authors.forename: In S
authors.initials: IS
authors.lastname: Lee
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D017352:Echo-Planar Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D007718:Knee Injuries / Q000000981:diagnostic imaging*; D007719:Knee Joint / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D059629:Signal-To-Noise Ratio; D017695:Soft Tissue Injuries / Q000000981:diagnostic imaging*; D013113:Spin Labels; D055815:Young Adult
chemical_list: D013113:Spin Labels