title: Marked prolongation of QRS duration after initiation of dronedarone therapy.
abstract: Dronedarone is a relatively new antiarrhythmic drug and is held to be less proarrhythmic than comparable compounds, although its proarrhythmia potential in humans has not been sufficiently evaluated. We describe a so far unreported dronedarone effect, namely a significant alteration of both the morphology and the duration of the QRS complex on the electro cardiogram in a 41-year old patient with symptomatic paroxysmal atrial fibrillation.
authors.affiliation: Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany.
authors.forename: Conrad
authors.initials: C
authors.lastname: Genz
authors.affiliation: Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany.
authors.forename: Hans D
authors.initials: HD
authors.lastname: Esperer
authors.affiliation: Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Schmeisser
authors.affiliation: Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany.
authors.forename: Ruediger C
authors.initials: RC
authors.lastname: Braun-Dullaeus
authors.affiliation: Section of Electrophysiology, Division of Cardiology, Otto-von-Guericke University, University Hospital Magdeburg, Magdeburg - Germany.
authors.forename: Samir M
authors.initials: SM
authors.lastname: Said
keywords: Adverse drug events; Antiarrhythmic drugs; Atrial fibrillation; Dronedarone