title: Assessment of Imatinib in the treatment of chronic myeloid leukemia in Gabon: a cohort of 17 cases.
abstract: The prognosis for chronic myeloid leukemia, the first hematologic malignancy for which successful targeted therapy has been developed, has changed markedly in the West. In developing countries, however, prognosis remains poor, mainly because of lack of access to treatment. The effort made by some nongovernmental organizations to distribute first-generation tyrosine kinase inhibitors free of charge has changed this situation in some regions, notably in sub-Saharan Africa and Gabon in particular. We report the results in a cohort of 17 patients.
authors.affiliation: Hôpital d'instruction des armées Omar Bongo Ondimba, Hôpital militaire de Libreville, BP 12038 Libreville, Gabon.
authors.forename: G L
authors.initials: GL
authors.lastname: Gaudong Mbethe
authors.affiliation: Hôpital d'instruction des armées Omar Bongo Ondimba, Hôpital militaire de Libreville, BP 12038 Libreville, Gabon.
authors.forename: D
authors.initials: D
authors.lastname: Mounguengui
authors.affiliation: Hôpital d'instruction des armées Omar Bongo Ondimba, Hôpital militaire de Libreville, BP 12038 Libreville, Gabon.
authors.forename: C
authors.initials: C
authors.lastname: Magne
authors.affiliation: Hôpital d'instruction des armées Omar Bongo Ondimba, Hôpital militaire de Libreville, BP 12038 Libreville, Gabon.
authors.forename: M
authors.initials: M
authors.lastname: Ondounda
authors.affiliation: Hôpital d'instruction des armées Omar Bongo Ondimba, Hôpital militaire de Libreville, BP 12038 Libreville, Gabon.
authors.forename: L
authors.initials: L
authors.lastname: Yboutsi
authors.affiliation: Centre hospitalo-universitaire de Libreville, Gabon.
authors.forename: J
authors.initials: J
authors.lastname: Ibaba
authors.affiliation: Centre hospitalo-universitaire de Libreville, Gabon.
authors.forename: J B
authors.initials: JB
authors.lastname: Moussavou Kombila
authors.affiliation: Centre hospitalo-universitaire de Libreville, Gabon.
authors.forename: J B
authors.initials: JB
authors.lastname: Boguikouma
authors.affiliation: Centre hospitalo-universitaire de Libreville, Gabon.
authors.forename: E
authors.initials: E
authors.lastname: Belembaogo
authors.affiliation: Hôpital d'instruction des armées Omar Bongo Ondimba, Hôpital militaire de Libreville, BP 12038 Libreville, Gabon.
authors.forename: J R
authors.initials: JR
authors.lastname: Nzenze
mesh_terms: D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D015331:Cohort Studies; D005260:Female; D005681:Gabon; D006801:Humans; D000068877:Imatinib Mesylate / Q000627:therapeutic use*; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000175:diagnosis / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents; D000068877:Imatinib Mesylate
keywords: Gabon; chronic myeloid leukemia; imatinib