title: Characteristics of Hyperautofluorescent Choroidal Vessels within the Macular Atrophic Area Using Spectral-Domain Optical Coherence Tomography.
abstract: OBJECTIVE
  The aim of this study was to clarify the characteristic findings in patients with geographic atrophy with or without hyperautofluorescent choroidal vessels within macular atrophic areas on short-wavelength fundus autofluorescence imaging.
  
  
  METHODS
  Sixty-seven eyes of 43 consecutive patients with macular atrophic areas were divided into groups with (group 1) and without (group 2) hyperautofluorescent choroidal vessels on fundus autofluorescence imaging and then retrospectively studied using spectral-domain optical coherence tomography.
  
  
  RESULTS
  In group 1 (n = 21), the average subfoveal choroidal thickness was 61.5 ± 20.1 μm, and the average foveal retinal thickness was 93.0 ± 51.3 μm. On the other hand, in group 2 (n = 46), the average subfoveal choroidal thickness was 200.7 ± 83.1 μm, and the average foveal retinal thickness was 109.2 ± 58.5 μm. Although retinal thickness did not differ significantly between the two groups (p = 0.28), the difference in choroidal thickness was statistically significant (p < 0.001).
  
  
  CONCLUSIONS
  Choroidal thinning might contribute to the hyperautofluorescence of choroidal vessels.
authors.affiliation: Department of Ophthalmology, School of Medicine, Nihon University, Tokyo, Japan.
authors.forename: Ari
authors.initials: A
authors.lastname: Shinojima
authors.forename: Ryusaburo
authors.initials: R
authors.lastname: Mori
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nakashizuka
authors.forename: Koji
authors.initials: K
authors.lastname: Tanaka
authors.forename: Kyoko
authors.initials: K
authors.lastname: Fujita
authors.forename: Akiyuki
authors.initials: A
authors.lastname: Kawamura
authors.forename: Miho
authors.initials: M
authors.lastname: Haruyama
authors.forename: Atsushi
authors.initials: A
authors.lastname: Yamamoto
authors.forename: Mitsuko
authors.initials: M
authors.lastname: Yuzawa
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002829:Choroid / Q000098:blood supply*; D005260:Female; D005451:Fluorescein Angiography; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D008268:Macular Degeneration / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D012171:Retinal Vessels / Q000473:pathology*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*