title: GenoType NTM-DR for Identifying Mycobacterium abscessus Subspecies and Determining Molecular Resistance.
abstract: We studied the performance of a new line probe assay for identifying the subspecies and determining the macrolide and aminoglycoside resistance levels of 50 Mycobacterium abscessus isolates. Agreement of GenoType NTM-DR results with sequencing and phenotypic resistance results was 92% for subspecies identification and 98% for determining molecular and phenotypic resistance.
authors.affiliation: Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany jan.kehrmann@uk-essen.de.
authors.forename: Jan
authors.initials: J
authors.lastname: Kehrmann
authors.affiliation: Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
authors.forename: Nermin
authors.initials: N
authors.lastname: Kurt
authors.affiliation: Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hanover, Germany.
authors.forename: Kai
authors.initials: K
authors.lastname: Rueger
authors.affiliation: Institute of Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hanover, Germany.
authors.forename: Franz-Christoph
authors.initials: FC
authors.lastname: Bange
authors.affiliation: Institute of Medical Microbiology, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Buer
mesh_terms: D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D024881:Drug Resistance, Bacterial; D060005:Genotyping Techniques / Q000379:methods*; D006801:Humans; D018942:Macrolides / Q000494:pharmacology; D008826:Microbial Sensitivity Tests / Q000379:methods*; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009161:Mycobacterium / Q000187:drug effects* / Q000302:isolation & purification*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D018942:Macrolides