title: Current strategies against invasive fungal infections in patients with aplastic anemia, strong power and weak weapon, a case report and review of literature.
abstract: We report an 18 year old boy with Aplastic anemia complicated by serious fungal rhinosinusitis. Despite prompt treatment and early repeated surgical debridements, he died after about more than 6 weeks of hard challenges with fungal infections. Current strategies against invasive fungal infections (IFIs) in patients with Aplastic anemia may be inadequate for the management of serious complications. Antifungal prophylaxis is highly recommended in pre-transplant period for severe form of Aplastic anemia.
authors.affiliation: Hematology Research Center, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran; Department of Pediatric Oncology, Amir Oncology Hospital, Farhang Shahr, Shiraz 7187915998, Iran.
authors.forename: Omid Reza
authors.initials: OR
authors.lastname: Zekavat
authors.affiliation: Professor Alborzi Clinical Microbiology Research Center, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran; Department of Pediatric Infectious Diseases, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Amanati
authors.affiliation: Department of Pediatric Oncology, Amir Oncology Hospital, Farhang Shahr, Shiraz 7187915998, Iran.
authors.forename: Fazl
authors.initials: F
authors.lastname: Saleh
authors.affiliation: Department of Pediatric Oncology, Amir Oncology Hospital, Farhang Shahr, Shiraz 7187915998, Iran.
authors.forename: Babak
authors.initials: B
authors.lastname: Abdolkarimi
authors.affiliation: Department of Pediatric Oncology, Amir Oncology Hospital, Farhang Shahr, Shiraz 7187915998, Iran.
authors.forename: Gholamreza
authors.initials: G
authors.lastname: Fathpour
authors.affiliation: Professor Alborzi Clinical Microbiology Research Center, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran.
authors.forename: Parisa
authors.initials: P
authors.lastname: Badiee
authors.affiliation: Department of Pathology Transplant Research Center, Namazi Hospital, Karimkhan Zand St., Shiraz 7193711351, Iran.
authors.forename: Bita
authors.initials: B
authors.lastname: Geramizadeh
keywords: Anemia, Aplastic; Antifungal agents; Aspergillosis; Mucormycosis