title: 3D printing of functional biomaterials for tissue engineering.
abstract: 3D printing is emerging as a powerful tool for tissue engineering by enabling 3D cell culture within complex 3D biomimetic architectures. This review discusses the prevailing 3D printing techniques and their most recent applications in building tissue constructs. The work associated with relatively well-known inkjet and extrusion-based bioprinting is presented with the latest advances in the fields. Emphasis is put on introducing two relatively new light-assisted bioprinting techniques, including digital light processing (DLP)-based bioprinting and laser based two photon polymerization (TPP) bioprinting. 3D bioprinting of vasculature network is particularly discussed for its foremost significance in maintaining tissue viability and promoting functional maturation. Limitations to current bioprinting approaches, as well as future directions of bioprinting functional tissues are also discussed.
authors.affiliation: NanoEngineering Department, University of California, San Diego, USA.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhu
authors.affiliation: Bioengineering Department, University of California, San Diego, USA.
authors.forename: Xuanyi
authors.initials: X
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, and Collaborative Innovation Center for Biotherapy, Chengdu, China.
authors.forename: Maling
authors.initials: M
authors.lastname: Gou
authors.affiliation: Department of Mechanical Engineering, Zhejiang University, China.
authors.forename: Deqing
authors.initials: D
authors.lastname: Mei
authors.affiliation: Shiley Eye Center and Institute for Genomic Medicine, University of California, San Diego, USA.
authors.forename: Kang
authors.initials: K
authors.lastname: Zhang
authors.affiliation: NanoEngineering Department, University of California, San Diego, USA; Bioengineering Department, University of California, San Diego, USA. Electronic address: chen168@eng.ucsd.edu.
authors.forename: Shaochen
authors.initials: S
authors.lastname: Chen
mesh_terms: D000818:Animals; D001672:Biocompatible Materials; D032701:Biomimetics; D062028:Bioprinting / Q000379:methods*; D006801:Humans; D066330:Printing, Three-Dimensional / Q000295:instrumentation*; D023822:Tissue Engineering / Q000295:instrumentation* / Q000379:methods*; D054457:Tissue Scaffolds
chemical_list: D001672:Biocompatible Materials