title: Declining trends in invasive orthopedic interventions for people with hemophilia enrolled in the Universal Data Collection program (2000-2010).
abstract: BACKGROUND
  Recurrent joint hemarthroses due to hemophilia (Factor VIII and Factor IX deficiency) often lead to invasive orthopedic interventions to decrease frequency of bleeding and/or to alleviate pain associated with end-stage hemophilic arthropathy.
  
  
  OBJECTIVE
  Identify trends in invasive orthopedic interventions among people with hemophilia who were enrolled in the Universal Data Collection (UDC) program during the period 2000-2010.
  
  
  METHODS
  Data were collected from 130 hemophilia treatment centers in the United States annually during the period 2000-2010, in collaboration with the Centers for Disease Control and Prevention (CDC). The number of visits in which an invasive orthopedic intervention was reported was expressed as a proportion of the total visits in each year of the program. Invasive orthopedic interventions consisted of arthroplasty, arthrodesis, and synovectomy. Joints included in this study were the shoulder, elbow, hip, knee, and ankle.
  
  
  RESULTS
  A 5.6% decrease in all invasive orthopedic interventions in all joints of people with hemophilia enrolled in the UDC program over the 11-year study period was observed.
  
  
  CONCLUSIONS
  These data reflect a declining trend in invasive orthopedic interventions in people with hemophilia. Further research is needed to understand the characteristics that may influence invasive orthopedic interventions.
authors.affiliation: Hemophilia Treatment Center, University of California, San Francisco, San Francisco, CA, USA.
authors.forename: P
authors.initials: P
authors.lastname: Tobase
authors.affiliation: Intermountain Hemophilia and Thrombosis Center Primary Children's Hospital, Salt Lake City, UT, USA.
authors.forename: H
authors.initials: H
authors.lastname: Lane
authors.affiliation: Division of Blood Disorders, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.
authors.forename: A-E-A
authors.initials: AE
authors.lastname: Siddiqi
authors.affiliation: The Hemophilia Center at Oregon Health and Science University, Portland, OR, USA.
authors.forename: R
authors.initials: R
authors.lastname: Ingram-Rich
authors.affiliation: Department of Physical Therapy, University of Utah College of Health, Salt Lake City, UT, USA.
authors.forename: R S
authors.initials: RS
authors.lastname: Ward
mesh_terms: D000843:Ankle Joint / Q000503:physiopathology; D001174:Arthrodesis / Q000706:statistics & numerical data / Q000639:trends; D001178:Arthroplasty / Q000706:statistics & numerical data / Q000639:trends; D003625:Data Collection; D006467:Hemophilia A / Q000150:complications*; D006470:Hemorrhage / Q000209:etiology; D006801:Humans; D007592:Joint Diseases / Q000150:complications* / Q000453:epidemiology / Q000601:surgery; D008297:Male
keywords: arthropathy; arthroplasty; hemophilia; orthopedic