title: Mast cells in lymphomas.
abstract: Tumor microenvironment is involved in the pathogenesis and progression of human lymphomas. The lymphoma microenvironment is composed by stromal cells, immune cells (macrophages, plasma cells, mast cells, eosinophils, basophils, T- and B-cells), blood vessels and extracellular matrix proteins. This article is focused on the role of mast cells in lymphoma progression and angiogenesis. Mast cells might be regarded in a future perspective as a new target for the adjuvant treatment of tumors, including lymphomas.
authors.affiliation: Department of Basic Medical Sciences, Neurosciences and Sensory Organs, University of Bari Medical School, Bari, Italy, National Cancer Institute "Giovanni Paolo II", Bari, Italy. Electronic address: domenico.ribatti@uniba.it.
authors.forename: Domenico
authors.initials: D
authors.lastname: Ribatti
mesh_terms: D018450:Disease Progression; D006801:Humans; D008223:Lymphoma / Q000473:pathology*; D008407:Mast Cells / Q000473:pathology*; D009389:Neovascularization, Pathologic / Q000378:metabolism; D059016:Tumor Microenvironment
keywords: Angiogenesis; Lymphoma; Mast cells; Tumor microenvironment; Tumor progression