title: Osteoporosis, osteoporotic fractures, and carotid artery calcification detected on panoramic radiographs in Japanese men and women.
abstract: OBJECTIVE
  We investigated the association among diagnosed osteoporosis, osteoporotic fractures, and carotid artery calcification (CAC) detected on panoramic radiographs. Additionally, we assessed whether osteoporosis or fractures could be predicted by an incidental finding of CAC.
  
  
  METHODS
  One thousand twenty-one patients participated in this study. Patients completed a structured questionnaire. Logistic regression analysis adjusted for covariates was used to calculate the odds ratio (95% confidence interval) for diagnosed osteoporosis or fractures according to the presence of CAC. Extended receiver operating characteristic (ROC) curve analysis was used to clarify whether osteoporosis or fractures were predicted by the detection of CAC.
  
  
  RESULTS
  The odds ratios for diagnosed osteoporosis or fracture associated with CAC were 1.82 (1.02-3.24) and 0.77 (0.33-1.77), respectively. The areas under the ROC curves for identifying patients with osteoporosis or fractures according to the detection of CAC were 0.54 and 0.50, respectively.
  
  
  CONCLUSIONS
  CAC may not be useful for identifying Japanese individuals with osteoporosis or those at risk of fracture, although the presence of CAC was significantly associated with a history of diagnosed osteoporosis without osteoporotic fractures.
authors.affiliation: Doctoral Student, Department of Hard Tissue Research, Graduate School of Oral Medicine, Matsumoto Dental University, Nagano, Japan.
authors.forename: Yae
authors.initials: Y
authors.lastname: Iwamoto
authors.affiliation: Associate Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Nagano, Japan.
authors.forename: Keiichi
authors.initials: K
authors.lastname: Uchida
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Nagano, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Sugino
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Nagano, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kuroiwa
authors.affiliation: Director, Center of Oral and Maxillofacial Surgery and Dental Implant, Nagano, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Kitamura
authors.affiliation: Professor and Chair, Department of Biochemistry, School of Dentistry, Matsumoto Dental University, Nagano, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Udagawa
authors.affiliation: Professor, Department of Oral and Maxillofacial Surgery, School of Dentistry, Matsumoto Dental University, Nagano, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Shinohara
authors.affiliation: Professor, Department of Regeneration and Medicine, Research Center for Radiation Genome Medicine, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
authors.forename: Yukihito
authors.initials: Y
authors.lastname: Higashi
authors.affiliation: Professor and Chair, Department of Oral and Maxillofacial Radiology, School of Dentistry, Matsumoto Dental University, Nagano, Japan. Electronic address: akiro@po.mdu.ac.jp.
authors.forename: Akira
authors.initials: A
authors.lastname: Taguchi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016893:Carotid Stenosis / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D033162:Incidental Findings; D007564:Japan; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000000981:diagnostic imaging*; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging*; D011237:Predictive Value of Tests; D011862:Radiography, Panoramic; D012307:Risk Factors; D011795:Surveys and Questionnaires; D061205:Vascular Calcification / Q000000981:diagnostic imaging*