title: Increased incidence of invasive meningococcal disease of serogroup C / clonal complex 11, Tuscany, Italy, 2015 to 2016.
abstract: We report an increase of serogroup C Neisseria meningitidis invasive meningococcal disease in Tuscany. From January 2015 to end February 2016, 43 cases were reported, among which 10 were fatal, compared to two cases caused by serogroup C recorded in 2014 and three in 2013. No secondary cases occurred. Thirty-five strains belonged to C:P1.5-1,10-8:F3-6:ST-11(cc11). Control measures have been adopted and immunisation campaigns implemented. Studies on risk factors and carriage are ongoing.
authors.affiliation: Department of Infectious, Parasitic & Immuno-mediated Diseases, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Stefanelli
authors.forename: Alessandro
authors.initials: A
authors.lastname: Miglietta
authors.forename: Patrizio
authors.initials: P
authors.lastname: Pezzotti
authors.forename: Cecilia
authors.initials: C
authors.lastname: Fazio
authors.forename: Arianna
authors.initials: A
authors.lastname: Neri
authors.forename: Paola
authors.initials: P
authors.lastname: Vacca
authors.forename: Fabio
authors.initials: F
authors.lastname: Voller
authors.forename: Fortunato P
authors.initials: FP
authors.lastname: D'Ancona
authors.forename: Raniero
authors.initials: R
authors.lastname: Guerra
authors.forename: Stefania
authors.initials: S
authors.lastname: Iannazzo
authors.forename: Maria Grazia
authors.initials: MG
authors.lastname: Pompa
authors.forename: Giovanni
authors.initials: G
authors.lastname: Rezza
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002353:Carrier State / Q000453:epidemiology; D002648:Child; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008585:Meningitis, Meningococcal / Q000175:diagnosis / Q000453:epidemiology*; D008589:Meningococcal Infections / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D038542:Neisseria meningitidis, Serogroup C / Q000235:genetics / Q000302:isolation & purification*; D012703:Serotyping; D014611:Vaccination / Q000706:statistics & numerical data; D055815:Young Adult
keywords: Neisseria meningitidis; outbreak; public health response; serogroup C