title: A Time Bomb for Leukemia.
abstract: Alterations of the circadian clock have been linked to cancer development. Puram et al. (in this issue) now uncover differential requirements between healthy hematopoietic and diseased leukemic stem cells for core circadian transcription factors, wherein leukemic cells depend on the clock machinery for survival and growth.
authors.affiliation: Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
authors.forename: Maria
authors.initials: M
authors.lastname: Maryanovich
authors.affiliation: Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA; Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: paul.frenette@einstein.yu.edu.
authors.forename: Paul S
authors.initials: PS
authors.lastname: Frenette
mesh_terms: D054042:Bombs; D057906:Circadian Clocks; D002940:Circadian Rhythm; D006801:Humans; D007938:Leukemia; D014157:Transcription Factors
chemical_list: D014157:Transcription Factors