title: Evaluation of hyperdense renal lesions incidentally detected on single-phase post-contrast CT using dual-energy CT.
abstract: OBJECTIVE
  To investigate the utility of dual-energy CT (DECT) for differentiating between solid and benign cystic lesions presenting as hyperdense renal lesions incidentally detected on single-phase post-contrast CT.
  
  
  METHODS
  90 hyperdense renal lesions incidentally detected on single-phase post-contrast CT were evaluated with follow-up DECT. DECT protocols included true non-contrast (TNC), DE corticomedullary and DE late nephrographic phase imaging. The CT numbers of hyperdense renal lesions were calculated on linearly blended and iodine overlay (IO) images, and the results were compared.
  
  
  RESULTS
  In total, 47 benign cystic and 43 solid renal lesions were analyzed. For differentiating between solid and benign cystic lesions on the two phases, the specificity and accuracy of all lesions and lesions <1.5 cm were statistically lower in IO images than in linearly blended images (p < 0.05), while those for lesions ≥1.5 cm were not statistically different between them (p > 0.05). For all types of lesions ≥1.5 cm, the CT numbers between linearly blended and IO images and between TNC and virtual non-contrast images were not statistically different (p > 0.05).
  
  
  CONCLUSIONS
  DECT may be useful for differentiating between solid and benign cystic lesions presenting as hyperdense renal lesions incidentally detected on single-phase post-contrast CT, particularly with the size ≥1.5 cm.
  
  
  CONCLUSIONS
  DECT may be used to characterize hyperdense renal lesions ≥1.5 cm incidentally detected on single-phase post-contrast CT, without the use of TNC images.
authors.affiliation: 1 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Dongik
authors.initials: D
authors.lastname: Cha
authors.affiliation: 1 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.|2 Department of Medical Device Management and Research, SAIHST, Sungkyunkwan University, Seoul, Republic of Korea.
authors.forename: Chan Kyo
authors.initials: CK
authors.lastname: Kim
authors.affiliation: 1 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Jung Jae
authors.initials: JJ
authors.lastname: Park
authors.affiliation: 1 Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Byung Kwan
authors.initials: BK
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D003287:Contrast Media / Q000008:administration & dosage; D003937:Diagnosis, Differential; D006801:Humans; D033162:Incidental Findings; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging* / Q000473:pathology*; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D008875:Middle Aged; D015588:Observer Variation; D015900:Radiography, Dual-Energy Scanned Projection / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D014057:Tomography, X-Ray Computed / Q000379:methods*; D055815:Young Adult
chemical_list: D003287:Contrast Media