title: Exposing the Molecular Machinery of BK Polyomavirus.
abstract: BK polyomavirus (BKV) is an opportunistic pathogen that poses a serious threat to organ transplant recipients. In this issue of Structure, Hurdiss and colleagues' (Hurdiss et al., 2016) beautiful new high-resolution cryo-EM reconstruction of BKV provides a structural roadmap for the ongoing development of therapeutic antibodies and vaccines targeting this potentially deadly virus. The study also serves as a platform for exploring the basic biology of virion assembly and infectious entry.
authors.affiliation: Center for Cancer Research, NCI, NIH, Bethesda, MD 20892, USA. Electronic address: buckc@mail.nih.gov.
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Buck
mesh_terms: D001739:BK Virus; D016030:Kidney Transplantation; D008958:Models, Molecular; D027601:Polyomavirus Infections