title: Spectral X-Ray Diffraction using a 6 Megapixel Photon Counting Array Detector.
abstract: Pixel-array array detectors allow single-photon counting to be performed on a massively parallel scale, with several million counting circuits and detectors in the array. Because the number of photoelectrons produced at the detector surface depends on the photon energy, these detectors offer the possibility of spectral imaging. In this work, a statistical model of the instrument response is used to calibrate the detector on a per-pixel basis. In turn, the calibrated sensor was used to perform separation of dual-energy diffraction measurements into two monochromatic images. Targeting applications include multi-wavelength diffraction to aid in protein structure determination and X-ray diffraction imaging.
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN, USA, 47906.
authors.forename: Ryan D
authors.initials: RD
authors.lastname: Muir
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN, USA, 47906.
authors.forename: Nicholas R
authors.initials: NR
authors.lastname: Pogranichniy
authors.affiliation: IMCA-CAT, Hauptman-Woodward Medical Research Institute, Argonne National Laboratory, Argonne, IL, USA, 60439.
authors.forename: J Lewis
authors.initials: JL
authors.lastname: Muir
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN, USA, 47906.
authors.forename: Shane Z
authors.initials: SZ
authors.lastname: Sullivan
authors.affiliation: IMCA-CAT, Hauptman-Woodward Medical Research Institute, Argonne National Laboratory, Argonne, IL, USA, 60439.
authors.forename: Kevin P
authors.initials: KP
authors.lastname: Battaile
authors.affiliation: IMCA-CAT, Hauptman-Woodward Medical Research Institute, Argonne National Laboratory, Argonne, IL, USA, 60439.
authors.forename: Anne M
authors.initials: AM
authors.lastname: Mulichak
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN, USA, 47906.
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Toth
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN, USA, 47906.
authors.forename: Lisa J
authors.initials: LJ
authors.lastname: Keefe
authors.affiliation: Department of Chemistry, Purdue University, 560 Oval Dr., West Lafayette, IN, USA, 47906.
authors.forename: Garth J
authors.initials: GJ
authors.lastname: Simpson