title: Recent advances in designed coiled coils and helical bundles with inorganic prosthetic groups-from structural to functional applications.
abstract: Recent contributions to the de novo design of metalloproteins based on coiled coils and helical bundles are described herein, with examples covering mononuclear, multinuclear, and metallo-porphyrin sites, as well as membrane soluble designs. Important progress is being made in the field with a diverse range of functionalities, sometimes beyond those found in biology, being successfully engineered into these simplified scaffolds and represents an exciting prospect for the future.
authors.affiliation: School of Chemistry, University of Birmingham, Edgbaston B15 2TT, UK. Electronic address: a.f.a.peacock@bham.ac.uk.
authors.forename: Anna Fa
authors.initials: AF
authors.lastname: Peacock
mesh_terms: D007287:Inorganic Chemicals / Q000737:chemistry*; D008667:Metalloproteins / Q000737:chemistry*; D011487:Protein Conformation
chemical_list: D007287:Inorganic Chemicals; D008667:Metalloproteins