title: Correlation between Doppler, Manual Morphometry, and Histopathology Based Morphometry of Radial Artery as a Conduit in Coronary Artery Bypass Grafting.
abstract: Background. Long-term graft patency is the major factor impacting survival after coronary artery bypass grafting. Arteries are superior in this regard. Radial artery is considered the second best conduit after internal mammary artery. Several studies have shown excellent radial artery patency. We evaluated the morphologic characteristics of radial artery by three modalities, (i) preoperative Doppler ultrasound, (ii) intraoperative manual morphometry, and (iii) postoperative histology-based morphometry, and compared these with the aim of validating Doppler as a noninvasive test of choice for preoperative assessment of radial artery. Methods. This was a prospective study involving 100 patients undergoing coronary artery bypass grafting in which radial artery was used. The radial artery was assessed using preoperative Doppler ultrasound studies, intraoperative morphometry, and postoperative histopathology and morphometry. The morphometric measurements included (i) luminal diameter, (ii) intimal and medial thickness, and (iii) intima-media thickness ratio. Results. Using Bland-Altman plots, there was a 95% limit of agreement between the preoperative Doppler measurements and the postoperative histopathology and morphometry. Conclusion. Doppler ultrasound is an accurate screening test for evaluation of radial artery, in terms of intimal/medial thickness and luminal diameter as a conduit in coronary artery bypass grafting and has been validated by both morphometric and histopathology based studies.
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Om Prakash
authors.initials: OP
authors.lastname: Yadava
authors.affiliation: Department of Cardiology, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Vinod
authors.initials: V
authors.lastname: Sharma
authors.affiliation: Department of Cardiac Anesthesiology, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Arvind
authors.initials: A
authors.lastname: Prakash
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Ahlawat
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Anirban
authors.identifier: 0000-0002-3653-8158
authors.initials: A
authors.lastname: Kundu
authors.affiliation: Department of Cardiothoracic Surgery, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Bikram K
authors.initials: BK
authors.lastname: Mohanty
authors.affiliation: Department of Cardiology, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India.
authors.forename: Rekha
authors.initials: R
authors.lastname: Mishra
authors.affiliation: Department of Pathology, All India Institute of Medical Sciences, New Delhi 110029, India.
authors.forename: Amit K
authors.initials: AK
authors.lastname: Dinda