title: [Treatment of primary hypothyroidism in adult patients].
abstract: The diagnosis of hypothyroidism is based on the findings of an increased serum TSH (above the reference range) and decreased serum free T4 (below the reference range) concentration. Treatment of subclinical hypothyroidism is indicated if serum THS is above 10 mU/l. For less severe forms of subclinical hypothyroidism, the treatment should be individually tailored. The treatment of choice is synthetic human levothyroxine. The goals for treatment are amelioration of symptoms and normalization of TSH and free T4 concentrations.
authors.forename: Pasi
authors.initials: P
authors.lastname: Salmela
authors.forename: Saara
authors.initials: S
authors.lastname: Metso
authors.forename: Leena
authors.initials: L
authors.lastname: Moilanen
authors.forename: Leo
authors.initials: L
authors.lastname: Niskanen
authors.forename: Pirjo
authors.initials: P
authors.lastname: Nuutila
authors.forename: Camilla
authors.initials: C
authors.lastname: Schalin-Jäntti
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D006801:Humans; D007037:Hypothyroidism / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy*; D013972:Thyrotropin / Q000097:blood; D013974:Thyroxine / Q000097:blood / Q000627:therapeutic use*
chemical_list: D015415:Biomarkers; D013972:Thyrotropin; D013974:Thyroxine