title: [Adult-onset opsoclonus-myoclonus-ataxia syndrome revealing rubella meningoencephalitis].
abstract: BACKGROUND
  Opsoclonus-myoclonus-ataxia (OMS) is a rare clinical syndrome, of paraneoplastic infectious, post-infectious, post-vaccinal or idiopathic origin.
  
  
  METHODS
  We report a 24-year-old young man who presented with gait disorder preceded by a febrile rash and retroauricular lymph nodes. Three days before admission, he had headache, vertigo, nausea and vomiting followed by gait unsteadiness and movement disorders of limbs and eyes. On examination, he had OMS syndrome. Brain MRI, total body scan, MIBG scintigraphy, tumor markers and onconeural antibodies were normal. Cerebro-spinal fluid (CSF) analysis showed lymphocytic meningitis. Positive serum and CSF immunoglobulin M antibody against rubella virus was demonstrated. He received acyclovir with full recovery within two weeks. We discuss the peculiarities of this association with a literature review.
  
  
  CONCLUSIONS
  This observation enlarges the spectrum of neurological manifestations of rubella as well as that of OMS etiologies.
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie. Electronic address: dr.nasri.amina@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Nasri
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Mansour
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: M
authors.initials: M
authors.lastname: Messelmani
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: A
authors.initials: A
authors.lastname: Riahi
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: H
authors.initials: H
authors.lastname: Derbali
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: I
authors.initials: I
authors.lastname: Bedoui
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: J
authors.initials: J
authors.lastname: Zaouali
authors.affiliation: Service de neurologie, hôpital militaire principal d'instruction de Tunis, Tunis, Tunisie.
authors.forename: R
authors.initials: R
authors.lastname: Mrissa
mesh_terms: D000212:Acyclovir / Q000627:therapeutic use; D000914:Antibodies, Viral / Q000097:blood / Q000134:cerebrospinal fluid; D000998:Antiviral Agents / Q000627:therapeutic use; D006801:Humans; D007075:Immunoglobulin M / Q000097:blood / Q000134:cerebrospinal fluid; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D053578:Opsoclonus-Myoclonus Syndrome / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D012409:Rubella / Q000175:diagnosis / Q000188:drug therapy / Q000821:virology*; D012412:Rubella virus / Q000276:immunology; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D000998:Antiviral Agents; D007075:Immunoglobulin M; D000212:Acyclovir
keywords: Adult; Adulte; Kinsbourne; Meningoencephalitis; Méningo-encéphalite; Opsoclonus-myoclonus; Rubella; Rubéole