title: Pharmacological Provocation of Outflow-Tract Tachycardia in a Patient With Brugada Syndrome.
abstract: We present a case of a symptomatic patient with Brugada syndrome, who had sustained right ventricular outflow tract tachycardia after pronounced exercise-induced ST segment elevation in V1and V2. In electrophysiological study he developed right ventricular outflow tract tachycardia provoked by combined infusion of ajmaline and orciprenaline. After ablation no further arrhythmia was provoked by pharmacological stimulation.
authors.affiliation: Cardiology, St Josefs-Hospital, Wiesbaden, Germany.
authors.forename: Gerd
authors.initials: G
authors.lastname: Bürkle
authors.affiliation: Intensive Care Medicine, Bürgerhospital, Frankfurt, Germany.
authors.forename: Henry
authors.initials: H
authors.lastname: Schäfer
authors.affiliation: Institute for Human Genetics, Martinsried, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Marschall
authors.affiliation: Cardiology, University Hospital, Brussels, Belgium.
authors.forename: Pedro
authors.initials: P
authors.lastname: Brugada
authors.affiliation: Cardiology, St Josefs-Hospital, Wiesbaden, Germany. Electronic address: joachimehrlich@t-online.de.
authors.forename: Joachim R
authors.initials: JR
authors.lastname: Ehrlich
mesh_terms: D000404:Ajmaline / Q000008:administration & dosage / Q000009:adverse effects; D000889:Anti-Arrhythmia Agents / Q000008:administration & dosage / Q000009:adverse effects; D053840:Brugada Syndrome / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D017115:Catheter Ablation / Q000379:methods*; D004562:Electrocardiography / Q000379:methods; D006329:Heart Conduction System / Q000187:drug effects / Q000503:physiopathology; D006801:Humans; D008297:Male; D009921:Metaproterenol / Q000008:administration & dosage / Q000009:adverse effects; D008875:Middle Aged; D013268:Stimulation, Chemical; D017180:Tachycardia, Ventricular / Q000139:chemically induced / Q000503:physiopathology / Q000517:prevention & control; D016896:Treatment Outcome
chemical_list: D000889:Anti-Arrhythmia Agents; D000404:Ajmaline; D009921:Metaproterenol