title: Comparison of femtosecond and excimer laser platforms available for corneal refractive surgery.
abstract: OBJECTIVE
  The evolution of laser technology has left today's refractive surgeon with a choice between multiple laser platforms. The purpose of this review is to compare currently available femtosecond and excimer laser platforms, providing a summary of current evidence.
  
  
  RESULTS
  Femtosecond lasers create LASIK flaps with better accuracy, uniformity, and predictability than mechanical microkeratomes. Newer higher-frequency femtosecond platforms elicit less inflammation, producing better visual outcomes. SMILE achieved similar safety, efficacy, and predictability as LASIK with greater preservation of corneal nerves and biomechanical strength. The emergence of wavefront technology has resulted in improved excimer laser treatments. Comparisons of wavefront-guided and wavefront-optimized treatments suggest that there is an advantage to using wavefront-guided platforms in terms of visual acuity and quality of vision. Topography-guided ablations are another well tolerated and effective option, especially in eyes with highly irregular corneas.
  
  
  CONCLUSIONS
  Advances in femtosecond and excimer laser technology have not only improved the safety and efficacy of refractive procedures, but have also led to the development of promising new treatment modalities, such as SMILE and the use of wavefront-guided and topography-guided ablation. Future studies and continued technological progress will help to better define the optimal use of these treatment platforms.
authors.affiliation: The Byers Eye Institute, Stanford University School of Medicine, Palo Alto, California, USA.
authors.forename: Lisa Y
authors.initials: LY
authors.lastname: Chen
authors.forename: Edward E
authors.initials: EE
authors.lastname: Manche
mesh_terms: D003315:Cornea / Q000601:surgery*; D006801:Humans; D006956:Hyperopia / Q000601:surgery; D020731:Keratomileusis, Laser In Situ / Q000379:methods; D053685:Laser Therapy / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D009216:Myopia / Q000601:surgery; D054140:Refractive Surgical Procedures / Q000379:methods*; D013524:Surgical Flaps; D016896:Treatment Outcome; D014792:Visual Acuity