title: Radiological and histopathological examination of apparent lytic lesions in allograft long bones-No cause for concern.
abstract: OBJECTIVE
  Identify the nature of apparent lytic lesions within human allograft specimens from patients with no known malignancy, using radiological and histopathological analysis.
  
  
  METHODS
  123 Post-retrieval radiographs from 23 donors were examined. Sixty-seven radiographs were noted to show apparent lytic lesions. The number, size, character and position of the apparent lesions were recorded.
  
  
  RESULTS
  CT scanning of 9 specimens confirmed the lesions to be of air pockets causing artefact. Histopathological analysis showed no malignant or pathological process.
  
  
  CONCLUSIONS
  Apparent lesions were not pathological.
  
  
  CONCLUSIONS
  Specimens with similar appearances, in donors with no malignancy, can be safely used in donation.
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
authors.forename: Mike
authors.initials: M
authors.lastname: Kent
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
authors.forename: Greg
authors.initials: G
authors.lastname: Brooker
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
authors.forename: Ryan
authors.initials: R
authors.lastname: Fisher
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
authors.forename: Geraldine
authors.initials: G
authors.lastname: Goh
authors.affiliation: Department of Radiology, Sir Charles Gairdner Hospital, Perth 6009, Western Australia Australia.
authors.forename: Ranieri Falcao
authors.initials: RF
authors.lastname: Aguiar
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia; PathWest, Sir Charles Gairdner Hospital, Perth 6009, Western Australia Australia.
authors.forename: John
authors.initials: J
authors.lastname: Papadimitriou
authors.affiliation: PathWest, Sir Charles Gairdner Hospital, Perth 6009, Western Australia Australia.
authors.forename: Daniel
authors.initials: D
authors.lastname: Wong
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
authors.forename: Richard
authors.initials: R
authors.lastname: Carey-Smith
authors.affiliation: PlusLife, Perth Orthopaedic Institute, Perth 6009, Western Australia, Australia.
authors.forename: Anne
authors.initials: A
authors.lastname: Cowie
keywords: Bone and tissue banking; Long bone allografts; Lytic lesions; Quality control; Tumour reconstruction