title: Primary Vaginal Adenosarcoma With Sarcomatous Overgrowth Arising in Recurrent Endometriosis: Feasibility of Laparoscopic Treatment and Review of the Literature.
abstract: We report a case of a primary vaginal adenosarcoma with sarcomatous overgrowth in a postmenopausal 58-year-old woman with recurrent endometriosis. In the past 5 years she underwent several biopsies of a polypoid lesion on the vaginal cuff, and the last histologic examination of the biopsy showed an adenosarcoma with "sarcomatous overgrowth" in a background of endometriosis. There was no evidence of distant metastatic disease on the diagnostic workup, and we performed a laparoscopy to remove the pelvic mass. We reviewed the literature on the electronic databases Medline, Embase, and Science Direct on articles published in English from 1990 to 2015. We identified 5 articles in which the surgical treatment was performed via a laparotomic approach. The present case is the first in the literature to report feasibility of laparoscopic treatment for this kind of pathology with a detailed description of the surgical technique.
authors.affiliation: Department of Obstetrics and Gynecologic Oncology and Minimally Invasive Pelvic Surgery Unit, International School of Surgical Anatomy, "Sacred Heart" Hospital, Negrar, Verona, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Pontrelli
authors.affiliation: Department of Biomedical, Experimental and Clinical Sciences, Division of Obstetrics and Gynecology, University of Florence, Florence, Italy. Electronic address: maurocoz@yahoo.it.
authors.forename: Mauro
authors.initials: M
authors.lastname: Cozzolino
authors.affiliation: Department of Obstetrics and Gynecologic Oncology and Minimally Invasive Pelvic Surgery Unit, International School of Surgical Anatomy, "Sacred Heart" Hospital, Negrar, Verona, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Stepniewska
authors.affiliation: Department of Obstetrics and Gynecologic Oncology and Minimally Invasive Pelvic Surgery Unit, International School of Surgical Anatomy, "Sacred Heart" Hospital, Negrar, Verona, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Bruni
authors.affiliation: Department of Human Pathology, "Sacred Heart" Hospital, Negrar, Verona, Italy.
authors.forename: Anna
authors.initials: A
authors.lastname: Pesci
authors.affiliation: Department of Obstetrics and Gynecologic Oncology and Minimally Invasive Pelvic Surgery Unit, International School of Surgical Anatomy, "Sacred Heart" Hospital, Negrar, Verona, Italy.
authors.forename: Marcello
authors.initials: M
authors.lastname: Ceccaroni
mesh_terms: D018195:Adenosarcoma / Q000473:pathology / Q000601:surgery*; D002471:Cell Transformation, Neoplastic; D004715:Endometriosis / Q000150:complications* / Q000473:pathology / Q000601:surgery; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008875:Middle Aged; D012008:Recurrence; D018615:Ultrasonography, Doppler, Color; D014625:Vaginal Neoplasms / Q000473:pathology / Q000601:surgery*
keywords: Endometriosis; Laparoscopy; Malignant transformation; Sarcomatous overgrowth; Vaginal adenosarcoma