title: Beyond efficacy and safety-the need for convenient and cost-effective iron therapy in health care.
abstract: The National Service Framework advocates correction of anaemia in patients with chronic kidney disease (CKD). Oral iron is insufficient, while intravenous (IV) supplementation replenishes and maintains iron stores. Previously, effective delivery of iron therapy using available parenteral preparations has been hampered by dosing schedules and the need in some cases of a test dose. The introduction in Europe of newer iron preparations, including iron isomaltoside 1000 (Monofer) and iron carboxymaltose (Ferinject), now offers a potentially safe, effective and time-efficient method of outpatient iron repletion. This may potentially lead to better cost-effectiveness in a resource-limited service.
authors.affiliation: Department of Renal Medicine , Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School , Hull Royal Infirmary, Anlaby Road, Kingston upon Hull, HU3 2JZ UK.
authors.forename: Sunil
authors.initials: S
authors.lastname: Bhandari
keywords: anaemia; chronic kidney disease; cost; ferumoxytol (Feraheme); iron carboxymaltose (Ferinject); iron isomaltoside 1000 (Monofer); iron sucrose (Venofer); low-molecular-weight iron dextran (Cosmofer); patient choice