title: Management of External Hemorrhage in Tactical Combat Casualty Care: The Adjunctive Use of XStat™ Compressed Hemostatic Sponges: TCCC Guidelines Change 15-03.
abstract: Exsanguination from wounds in the so-called junctional regions of the body (i.e., the neck, the axilla, and the groin) was responsible for 19% of the combat fatalities who died from potentially survivable wounds sustained in Afghanistan or Iraq during 2001 to 2011. The development of improved techniques and technology to manage junctional hemorrhage has been identified in the past as a high-priority item by the Committee on Tactical Combat Casualty Care (CoTCCC) and the Army Surgeon General's Dismounted Complex Blast Injury (DCBI) Task Force. Additionally, prehospital care providers have had limited options with which to manage hemorrhage resulting from deep, narrow-track, penetrating trauma. XStat™ is a new product recently approved by the US Food and Drug Administration as a hemostatic adjunct to aid in the control of bleeding from junctional wounds in the groin or axilla. XStat has now been recommended by the CoTCCC as another tool for the combat medical provider to use in the management of junctional hemorrhage. The evidence that supports adding XStat to the TCCC Guidelines for the treatment of external hemorrhage is summarized in this paper.
authors.forename: Kyle
authors.initials: K
authors.lastname: Sims
authors.forename: Harold R
authors.initials: HR
authors.lastname: Montgomery
authors.forename: Paul
authors.initials: P
authors.lastname: Dituro
authors.forename: Bijan S
authors.initials: BS
authors.lastname: Kheirabadi
authors.forename: Frank K
authors.initials: FK
authors.lastname: Butler
mesh_terms: D001365:Axilla / Q000293:injuries*; D006119:Groin / Q000293:injuries*; D006470:Hemorrhage / Q000209:etiology / Q000628:therapy*; D006490:Hemostatics / Q000008:administration & dosage*; D006801:Humans; D008887:Military Medicine / Q000592:standards*; D017410:Practice Guidelines as Topic; D015503:Surgical Sponges; D000067398:War-Related Injuries / Q000150:complications / Q000628:therapy
chemical_list: D006490:Hemostatics