title: Hippo/Yap Signaling in Cardiac Development and Regeneration.
abstract: The heart has historically been considered to be a non-regenerative organ. Recent insights have suggested that cardiomyocytes have a small but measurable ability to regenerate. Moreover, recent work has also shown that manipulating the expression of specific genetic pathways can improve the ability of the heart to repair itself. These new insights set the stage for the development of new treatments for heart failure.
authors.affiliation: Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA.|Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, 77030, USA.
authors.forename: Yang
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA.
authors.forename: John
authors.initials: J
authors.lastname: Leach
authors.affiliation: Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Molecular Physiology and Biophysics, Baylor College of Medicine, Houston, TX, 77030, USA. jfmartin@bcm.edu.|Institute of Biosciences and Technology, Texas A&M Health Science Center, Houston, TX, 77030, USA. jfmartin@bcm.edu.|Cardiomyocyte Renewal Laboratory, Texas Heart Institute, Houston, TX, 77030, USA. jfmartin@bcm.edu.|Program in Developmental Biology, Baylor College of Medicine, One Baylor Plaza, Houston, TX, 77030, USA. jfmartin@bcm.edu.|Cardiovascular Research Institute, Baylor College of Medicine, Houston, TX, 77030, USA. jfmartin@bcm.edu.
authors.forename: James F
authors.initials: JF
authors.lastname: Martin
keywords: Cardiac development; Cardiac regeneration; Hippo/Yap signaling