title: Primary rectal mucosa-associated lymphoid tissue lymphoma in a patient with previously identified primary biliary cirrhosis and secondary Sjögren's syndrome.
abstract: An 83-year-old female began treatment with prednisolone and ursodeoxycholic acid at 62 years of age, following a diagnosis of primary biliary cirrhosis (PBC) and secondary Sjögren's syndrome (SjS). With persisting bloody stools, the patient underwent colonoscopy at 83 years of age. Histopathological evaluation revealed mucosa-associated lymphoid tissue (MALT) lymphoma. The elevated rectal lesion resolved with rituximab treatment. We report this case because although patients with SjS are at increased risk of malignant lymphoma, primary rectal MALT lymphoma is very uncommon in association with PBC and secondary SjS.
authors.affiliation: Department of Gastroenterology, Public Soma General Hospital, Fukushima, Japan.|Department of Gastroenterology and Rheumatology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Kawashima
authors.affiliation: Department of Gastroenterology and Rheumatology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan. k-kata@fmu.ac.jp.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Katakura
authors.affiliation: Department of Gastroenterology, Public Soma General Hospital, Fukushima, Japan.
authors.forename: Yuta
authors.initials: Y
authors.lastname: Takahashi
authors.affiliation: Department of Gastroenterology, Public Soma General Hospital, Fukushima, Japan.|Department of Gastroenterology and Rheumatology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Asama
authors.affiliation: Department of Gastroenterology and Rheumatology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Fujiwara
authors.affiliation: Department of Gastroenterology, Public Soma General Hospital, Fukushima, Japan.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Kumakawa
authors.affiliation: Department of Gastroenterology and Rheumatology, Fukushima Medical University, 1 Hikarigaoka, Fukushima, 960-1295, Japan.
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use; D001706:Biopsy; D003106:Colon / Q000473:pathology; D003113:Colonoscopy; D005260:Female; D006801:Humans; D008105:Liver Cirrhosis, Biliary / Q000150:complications*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography; D012004:Rectal Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology* / Q000473:pathology; D000069283:Rituximab / Q000627:therapeutic use; D012859:Sjogren's Syndrome / Q000150:complications*
chemical_list: D000970:Antineoplastic Agents; D000069283:Rituximab
keywords: Primary biliary cirrhosis; Rectal MALT lymphoma; Secondary Sjögren’s syndrome