title: Anemia in the frail, elderly patient.
abstract: Anemia and frailty are two common findings in geriatric patients and have been shown to be associated with poor outcomes in this patient group. Recent studies have contributed to the growing evidence of a possible association with the age-related chronic inflammatory status known as "inflammaging". These findings do not only give a better insight into the pathogenesis of anemia in frailty, but also offer new treatment options. The present article focuses on this assumed association between anemia, frailty, and inflammaging and summarizes current management options for anemia in frail patients.
authors.affiliation: Ageing Clinical Research, Department II of Internal Medicine, University Hospital Cologne, Cologne, Germany; Department of Geriatrics, St Marien Hospital Cologne, Cologne, Germany.
authors.forename: Gabriele
authors.initials: G
authors.lastname: Röhrig
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D000740:Anemia / Q000503:physiopathology* / Q000628:therapy; D004912:Erythrocytes / Q000378:metabolism*; D016330:Frail Elderly; D015577:Geriatric Assessment; D006801:Humans; D007249:Inflammation / Q000503:physiopathology* / Q000628:therapy; D017382:Reactive Oxygen Species / Q000378:metabolism*
chemical_list: D017382:Reactive Oxygen Species
keywords: anemia of chronic inflammation; eryptosis; frailty; inflammaging; reactive oxygen species