title: N(2)-Selective Iodofunctionalization of Olefins with NH-1,2,3-Triazoles to provide N(2)-Alkyl-Substituted 1,2,3-Triazoles.
abstract: A new method was developed to synthesize N(2)-alkyl-substituted 1,2,3-triazole through N-iodosuccinimide (NIS) mediated iodofuctionalization reaction of the alkene group with bi-, mono-, and unsubstituted NH-1,2,3-triazoles. The favored N-1 type hydrogen bond between the iodonium ion intermediate and 1,2,3-triazole was supposed to be generated, which gave the desired N(2)-alkyl triazole with a high N(2)-selectivity.
authors.affiliation: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Zhu
authors.affiliation: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors.forename: Xiao-Qi
authors.initials: XQ
authors.lastname: Xu
authors.affiliation: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors.forename: Jin-Wei
authors.initials: JW
authors.lastname: Shi
authors.affiliation: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors.forename: Bai-Ling
authors.initials: BL
authors.lastname: Chen
authors.affiliation: Department of Chemistry, Renmin University of China , Beijing 100872, China.
authors.forename: Zili
authors.initials: Z
authors.lastname: Chen