title: Enantioselective intramolecular cyclization of alkynyl esters catalyzed by a chiral Brønsted base.
abstract: An enantioselective intramolecular cyclization reaction of alkynyl esters was developed, which employs a Brønsted base catalyst generated in situ from a chiral Schiff base and t-BuOK. This reaction is a rare example of the enantioselective intramolecular addition of simple ester enolates to alkynes under Brønsted base catalysis.
authors.affiliation: Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan. mterada@m.tohoku.ac.jp.
authors.forename: Azusa
authors.initials: A
authors.lastname: Kondoh
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Hoa Thi Quynh
authors.initials: HT
authors.lastname: Tran
authors.affiliation: Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Kyoko
authors.initials: K
authors.lastname: Kimura
authors.affiliation: Research and Analytical Center for Giant Molecules, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan. mterada@m.tohoku.ac.jp and Department of Chemistry, Graduate School of Science, Tohoku University, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Terada