title: Effects of tail docking on the expression of genes related to lipid metabolism in Lanzhou fat-tailed sheep.
abstract: To evaluate stearoyl-CoA desaturase (SCD), hormone-sensitive lipase (HSL), lipoprotein lipase (LPL), and peroxisome proliferator-activated receptor (PPARγ) expression in Lanzhou fat-tailed sheep (with and without docked tails), 18 rams were randomly divided into two equal groups (docked group, LT; control group, LC). These data were also used to increase the understanding of sheep fat deposition and metabolism. All animals were harvested at the age of 18 months, and expression was determined for 10 tissues. The results indicated that the fat weight of each tissue in LT was higher than in LC (P < 0.05). SCD expression in semitendinosus, omentum majus fat (OF), subcutaneous fat, kidney fat (KF), and subcutaneous rump fat was higher in LT than in LC rams (P < 0.05). Trends (P < 0.10) associated with higher HSL expression of LC in comparison to that of LT rams in intestinal fat, OF, and KF tissues were detected. Numerically, LPL expression was the highest in KF, OF, and kidney tissues, but there were few differences (P > 0.10). PPARγexpression was greater in LT than in LC rams in liver tissues (P < 0.05), but there were few differences in other tissues. No significant differences were found with regard to the regression analysis of expression and adipose tissue weights, but the two indices exhibited the same trend. The results indicated that changes in fatty deposits may be due to the common control of docking management and the minor effects associated with the regulation of SCD, HSL, LPL, and PPARγexpression.
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Yue
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: X
authors.initials: X
authors.lastname: Cheng
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: S G
authors.initials: SG
authors.lastname: Zhao
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Liu
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: L S
authors.initials: LS
authors.lastname: Liu
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: R
authors.initials: R
authors.lastname: Zhou
authors.affiliation: College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, Gansu, China.
authors.forename: J P
authors.initials: JP
authors.lastname: Wu
authors.affiliation: B&B Research & Development, LLC, El Reno, OK, USA.
authors.forename: M A
authors.initials: MA
authors.lastname: Brown
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000671:Amputation, Surgical / Q000662:veterinary; D000818:Animals; D005227:Fatty Acids / Q000378:metabolism; D050356:Lipid Metabolism / Q000502:physiology*; D008071:Lipoprotein Lipase / Q000378:metabolism; D008297:Male; D047495:PPAR gamma / Q000378:metabolism; D012756:Sheep; D034561:Sheep, Domestic; D013230:Stearoyl-CoA Desaturase / Q000378:metabolism; D013623:Tail / Q000601:surgery*
chemical_list: D005227:Fatty Acids; D047495:PPAR gamma; D013230:Stearoyl-CoA Desaturase; D008071:Lipoprotein Lipase