title: Analysis of long-term follow-up and examination of pathological liver tissue in chronic hepatitis E.
abstract: Hepatitis E is chronic in immunocompromised patients with HIV infection, organ transplant, or radiation and chemotherapy. General cases are not chronic. Fifty-five cases were collected and followed up for 4-14 years. It was found that chronic hepatitis E is more common in males, but a high degree of inflammatory activity and fibrosis was not evident. After 4-14 years of follow-up observation, cirrhosis or liver cancer did not appear. This is significantly different from the hepatitis B and C viruses. We speculated that the chronic mechanism in the general patients with hepatitis E might be different from that of immunocompromised cases.
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China. Electronic address: liuli197210@163.com.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Yunhua
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Yingrong
authors.initials: Y
authors.lastname: Du
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Chunyun
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Weikun
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Huimin
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Jia
authors.affiliation: Department of Hepatopathy, The Third People's Hospital of Kunming City, Kunming, China.
authors.forename: Lixian
authors.initials: L
authors.lastname: Chang
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D016751:Hepatitis E / Q000503:physiopathology* / Q000821:virology; D016752:Hepatitis E virus; D006521:Hepatitis, Chronic / Q000503:physiopathology* / Q000821:virology; D006801:Humans; D008099:Liver / Q000473:pathology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged
keywords: Chronic; Hepatitis E; Liver tissue