title: High-pressure differential scanning microcalorimeter.
abstract: A differential scanning microcalorimeter for studying thermotropic conformational transitions of biopolymers at high pressure has been designed. The calorimeter allows taking measurements of partial heat capacity of biopolymer solutions vs. temperature at pressures up to 3000 atm. The principles of operation of the device, methods of its calibration, as well as possible applications are discussed.
authors.affiliation: Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Senin
authors.affiliation: L. F. Vereshchagin Institute for High Pressure Physics, Russian Academy of Sciences, 142190 Troitsk, Moscow Region, Russia.
authors.forename: L N
authors.initials: LN
authors.lastname: Dzhavadov
authors.affiliation: Institute of Protein Research, Russian Academy of Sciences, 142290 Pushchino, Moscow Region, Russia.
authors.forename: S A
authors.initials: SA
authors.lastname: Potekhin
mesh_terms: D002138:Calibration; D002151:Calorimetry / Q000295:instrumentation*; D011312:Pressure; D013696:Temperature