title: Immunotherapy for Non-Small Cell Lung Cancer - Finally a Hint of Hope.
abstract: Lung cancer is a major public health problem worldwide and the leading cause of cancerrelated mortality in developed countries. Significant advances have been made especially with the discovery of targeted agents. However, only a small proportion of patients carry activating mutations; until recently conventional chemotherapy and angiogenesis inhibitors were the preferred treatment for the vast majority of patients. Now, the successful experience of anti-PD-1 agents may have opened the door to a novel and previously unexplored dimension in the treatment of lung cancer: immunotherapy. In this mini-review we will discuss the current applications and future consequences related this topic, paying special attention to the clinical studies that constitute the scientific evidence to supports its use.
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Recondo
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Recondo
authors.forename: Fernando
authors.initials: F
authors.lastname: Galanternik
authors.forename: Martín
authors.initials: M
authors.lastname: Greco
authors.forename: Máximo
authors.initials: M
authors.lastname: de la Vega
authors.lastname: E Diaz Cantón
authors.affiliation: 5170 U.S. Route 60 East, Huntington, WV 25705, USA. meval78@yahoo.com.
authors.forename: Matías E
authors.initials: ME
authors.lastname: Valsecchi
mesh_terms: D002289:Carcinoma, Non-Small-Cell Lung / Q000188:drug therapy*; D006801:Humans; D007167:Immunotherapy; D008175:Lung Neoplasms / Q000188:drug therapy*