title: High-intensity focused ultrasound treatment for intra-abdominal desmoid tumors: a report of four cases.
abstract: Desmoid tumors are rare clonal fibroblastic proliferations that can arise at abdominal or extra-abdominal sites. Complete surgical resection is the primary treatment for resectable desmoid tumors, but a high rate of local recurrence has been reported even after complete resection. For patients with a recurrent tumor, the goals of treatment are to control the recurrence, maintain quality of life, and prolong survival. Radiofrequency ablation, radiotherapy, chemotherapy, and other medical therapies can be used as alternative methods, but there are considerable controversies over the roles of these methods in the management of desmoid tumors. High-intensity focused ultrasound (HIFU) is a minimally invasive and effective method for treatment of solid tumors. We used HIFU to treat four patients with intra-abdominal desmoid tumors from June 2011 to September 2013. Post-procedural pain was seen in all patients. One patient had an intra-abdominal abscess and another suffered a slight injury to the femoral nerve. The patients were followed up for 19-46 months (mean 34 months) until April 2015. The tumor in one patient disappeared, and no tumor progression was observed in the other patients.
authors.affiliation: Department of Surgical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Hangzhou, Zhejiang Province, People's Republic of China.|The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang, 310009, People's Republic of China.
authors.forename: Yulan
authors.initials: Y
authors.lastname: Shi
authors.affiliation: Cancer Institute, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310009, People's Republic of China.
authors.forename: Yanqin
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Surgical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Hangzhou, Zhejiang Province, People's Republic of China.|The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang, 310009, People's Republic of China.
authors.forename: Meiqi
authors.initials: M
authors.lastname: Zhou
authors.affiliation: Department of Surgical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Hangzhou, Zhejiang Province, People's Republic of China.|The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang, 310009, People's Republic of China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Ying
authors.affiliation: Department of Surgical Oncology, Key Laboratory of Cancer Prevention and Intervention, National Ministry of Education, Key Laboratory of Molecular Biology in Medical Sciences, Hangzhou, Zhejiang Province, People's Republic of China. huhu3570@gmail.com.|The Second Affiliated Hospital, Zhejiang University School of Medicine, 88 Jiefang Road, Hangzhou, Zhejiang, 310009, People's Republic of China. huhu3570@gmail.com.
authors.forename: Xiaoye
authors.initials: X
authors.lastname: Hu
mesh_terms: D000008:Abdominal Neoplasms / Q000000981:diagnostic imaging / Q000628:therapy*; D000328:Adult; D005260:Female; D018221:Fibromatosis, Abdominal / Q000000981:diagnostic imaging / Q000628:therapy*; D057086:High-Intensity Focused Ultrasound Ablation / Q000379:methods; D006801:Humans
keywords: Aggressive fibromatosis; Desmoid tumor; Desmoid-type fibromatosis; HIFU