title: Association between Self-Reported Health Status and Frailty in Community-Dwelling Elderly.
abstract: BACKGROUND
  The phenotype of frailty proposed by Fried et al. has been related with increased vulnerability for the development of adverse health-related outcomes. However, this phenotype is not often used in daily clinical practice. On the other hand, poor self-reported health status (SRHS) has been associated with similar adverse health-related outcomes.
  
  
  OBJECTIVE
  To determine the association between poor SRHS and frailty.
  
  
  METHODS
  Cross-sectional study of 927 community-dwelling elderly aged 70 and older, participating in the Mexican Study of Nutritional and Psychosocial Markers of Frailty.
  
  
  METHODS
  SRHS was established by the question "How do you rate your health status in general?" Frailty was defined according to the phenotype proposed by Fried et al. The association between SRHS and frailty was determined through the construction of multinomial logistic regression models. Final analyses were adjusted by socio-demographic and health covariates, including depressive symptoms. Also, agreement between SRHS and the phenotype of frailty was explored.
  
  
  RESULTS
  Prevalence of frailty was 14.1%, and 4.4% of participants rated their health status as "poor". The unadjusted regression analyses demonstrated that fair and poor SRHS were significantly associated with prefrail and frail status. After adjustment for multiple covariates, the association remained statistically significant. However, in the final adjustment for depressive symptoms, only the association between poor SRHS and frail status continued to be statistically significant. Fair agreement between poor SRHS and frail status was also found.
  
  
  CONCLUSIONS
  Poor SRHS shares common correlates as well as health-related adverse outcomes with frailty syndrome, and remains associated with it even when possible confounders are taken into account. Therefore, poor SRHS could be further explored as an option for frailty syndrome screening.
authors.affiliation: José Alberto Ávila-Funes. Department of Geriatrics. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Vasco de Quiroga 15. CP 14000; Tlalpan, México, Distrito Federal. Phone: + 52 (55) 54 87 09 00, 5703. E-mail: avilafunes@live.com.mx.
authors.forename: A M
authors.initials: AM
authors.lastname: González-Pichardo
authors.forename: A P
authors.initials: AP
authors.lastname: Navarrete-Reyes
authors.forename: H
authors.initials: H
authors.lastname: Adame-Encarnación
authors.forename: S
authors.initials: S
authors.lastname: Aguilar-Navarro
authors.forename: J M A
authors.initials: JM
authors.lastname: García-Lara
authors.forename: H
authors.initials: H
authors.lastname: Amieva
authors.forename: J A
authors.initials: JA
authors.lastname: Avila-Funes