title: [Lidocaine-containing hyaluronic acid filler on a CPM® basis for lip augmentation : Experience from clinical practice].
abstract: BACKGROUND
  Lip augmentation with hyaluronic acid fillers is an established procedure. As monophasic polydensified hyaluronic acid products with variable density CPM-HAL1 (Belotero® Balance Lidocaine) and CPM-HAL2 (Belotero® Intense Lidocaine) are qualified for beautification and particularly natural-looking rejuvenation, respectively.
  
  
  OBJECTIVE
  Assessment of handling and outcome of lip augmentation using the lidocaine-containing hyaluronic acid fillers CPM-HAL1 and CPM-HAL2.
  
  
  METHODS
  Data from patients who received lip augmentation by means of bautification and/or rejuvenation using CPM-HAL1 and/or CPM-HAL2 were documented. Observation period was 4 months, with assessment of natural outcome, evenness, handling, fluidity, distribution, malleability, tolerability, as well as patient satisfaction and pain.
  
  
  RESULTS
  In total, 146 patients from 21 German centres participated. Physicians rated natural outcome and evenness as good or very good for > 95 % of patients. Handling, fluidity, distribution and malleability were assessed for both fillers as good or very good in > 91 % of patients. At every evaluation point, more than 93 % of patients were very or very much satisfied with the product. A total of 125 patients (85.6 %) experienced transient injection-related side effects. Pain intensity during the procedure was mild (2.72 ± 1.72 on the 0-10 pain assessment scale) and abated markedly within 30 min (0.42 ± 0.57).
  
  
  CONCLUSIONS
  Lip augmentation with hyaluronic acid fillers produced a long-term cosmetic result. Due to the lidocaine content, procedural pain was low and transient. Accordingly, a high degree of patient satisfaction was achieved that was maintained throughout the observation period.
authors.affiliation: Haut- & Lasercentrum Potsdam, Kurfürstenstr. 40, 14467, Potsdam, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Fischer
authors.affiliation: Rosenparkklinik GmbH, Heidelberger Landstr. 18-20, 64297, Darmstadt, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Sattler
authors.affiliation: Klinik für Dermatologie und Allergologie, Ludwig-Maximilians-Universität München, Frauenlobstr. 9-11, 80337, München, Deutschland. Gerd.Gauglitz@med.uni-muenchen.de.
authors.forename: G
authors.initials: G
authors.lastname: Gauglitz
mesh_terms: D000328:Adult; D000779:Anesthetics, Local / Q000008:administration & dosage; D003357:Cosmetic Techniques / Q000009:adverse effects / Q000523:psychology; D003358:Cosmetics / Q000008:administration & dosage / Q000009:adverse effects; D000067548:Dermal Fillers / Q000008:administration & dosage* / Q000009:adverse effects; D004338:Drug Combinations; D005157:Facial Pain / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006801:Humans; D006820:Hyaluronic Acid / Q000008:administration & dosage* / Q000009:adverse effects; D008012:Lidocaine / Q000008:administration & dosage*; D008046:Lip / Q000033:anatomy & histology / Q000000981:diagnostic imaging*; D008297:Male; D017060:Patient Satisfaction; D012060:Rejuvenation / Q000523:psychology; D015595:Skin Aging / Q000187:drug effects; D016896:Treatment Outcome
chemical_list: D000779:Anesthetics, Local; D003358:Cosmetics; D000067548:Dermal Fillers; D004338:Drug Combinations; C584568:belotero balance; D006820:Hyaluronic Acid; D008012:Lidocaine
keywords: Adverse effects; Hyaluronic acid; Injection; Pain; Satisfaction