title: Regulation of nuclear shape and size in plants.
abstract: Nuclear shape and size changes have long been used by cytopathologists to diagnose, stage, and prognose cancer. However, the underlying causalities and molecular mechanisms are largely unknown. The current eukaryotic tree of life groups eukaryotes into five supergroups, with all organisms between humans and yeast falling into the supergroup Opisthokonta. The emergence of model organisms with strong molecular genetic methodology in the other supergroups has recently facilitated a broader evolutionary approach to pressing biological questions. Here, we review what is known about the control of nuclear shape and size in the Archaeplastidae, the supergroup containing the higher plants. We discuss common themes as well as differences toward a more generalized model of how eukaryotic organisms regulate nuclear morphology.
authors.affiliation: Department of Molecular Genetics, The Ohio State University, 520 Aronoff Laboratory, 318 West 12th Avenue, Columbus, OH 43210, USA. Electronic address: meier.56@osu.edu.
authors.forename: Iris
authors.initials: I
authors.lastname: Meier
authors.affiliation: Department of Molecular Genetics, The Ohio State University, 520 Aronoff Laboratory, 318 West 12th Avenue, Columbus, OH 43210, USA.
authors.forename: Anna Hn
authors.initials: AH
authors.lastname: Griffis
authors.affiliation: Department of Molecular Genetics, The Ohio State University, 520 Aronoff Laboratory, 318 West 12th Avenue, Columbus, OH 43210, USA.
authors.forename: Norman R
authors.initials: NR
authors.lastname: Groves
authors.affiliation: Department of Molecular Genetics, The Ohio State University, 520 Aronoff Laboratory, 318 West 12th Avenue, Columbus, OH 43210, USA.
authors.forename: Alecia
authors.initials: A
authors.lastname: Wagner
mesh_terms: D005075:Biological Evolution; D002467:Cell Nucleus; D053144:Cell Nucleus Shape; D005057:Eukaryotic Cells / Q000145:classification / Q000166:cytology; D009687:Nuclear Proteins / Q000378:metabolism; D053141:Organelle Size; D059828:Plant Cells / Q000378:metabolism*; D010940:Plant Proteins / Q000378:metabolism; D010944:Plants / Q000235:genetics / Q000378:metabolism
chemical_list: D009687:Nuclear Proteins; D010940:Plant Proteins