title: Potential of acute phase proteins as predictor of postpartum uterine infections during transition period and its regulatory mechanism in dairy cattle.
abstract: Among the various systemic reactions against infection or injury, the acute phase response is the cascade of reaction and mostly coordinated by cytokines-mediated acute phase proteins (APPs) production. Since APPs are sensitive innate immune molecules, they are useful for early detection of inflammation in bovines and believed to be better discriminators than routine hematological parameters. Therefore, the possibility of using APPs as a diagnostic and prognostic marker of inflammation in major bovine health disorders including postpartum uterine infection has been explored by many workers. In this review, we discussed specifically importance of postpartum uterine infection, the role of energy balance in uterine infections and potential of APPs as a predictor of postpartum uterine infections during the transition period and its regulatory mechanism in dairy cattle.
authors.affiliation: Southern Regional Station, ICAR - National Dairy Research Institute, Adugodi, Bengaluru - 560 030, Karnataka, India.
authors.forename: A
authors.initials: A
authors.lastname: Manimaran
authors.affiliation: Theriogenology Laboratory, ICAR - National Dairy Research Institute, Karnal-132 001, Haryana, Uttar Pradesh, India.
authors.forename: A
authors.initials: A
authors.lastname: Kumaresan
authors.affiliation: Southern Regional Station, ICAR - National Dairy Research Institute, Adugodi, Bengaluru - 560 030, Karnataka, India.
authors.forename: S
authors.initials: S
authors.lastname: Jeyakumar
authors.affiliation: Theriogenology Laboratory, ICAR - National Dairy Research Institute, Karnal-132 001, Haryana, Uttar Pradesh, India.
authors.forename: T K
authors.initials: TK
authors.lastname: Mohanty
authors.affiliation: Southern Regional Station, ICAR - National Dairy Research Institute, Adugodi, Bengaluru - 560 030, Karnataka, India.
authors.forename: V
authors.initials: V
authors.lastname: Sejian
authors.affiliation: Southern Regional Station, ICAR - National Dairy Research Institute, Adugodi, Bengaluru - 560 030, Karnataka, India.
authors.forename: Narender
authors.initials: N
authors.lastname: Kumar
authors.affiliation: ICAR - National Dairy Research Institute, Karnal - 132 001, Haryana, India.
authors.forename: L
authors.initials: L
authors.lastname: Sreela
authors.affiliation: ICAR - National Dairy Research Institute, Karnal - 132 001, Haryana, India.
authors.forename: M Arul
authors.initials: MA
authors.lastname: Prakash
authors.affiliation: ICAR - National Dairy Research Institute, Karnal - 132 001, Haryana, India.
authors.forename: P
authors.initials: P
authors.lastname: Mooventhan
authors.affiliation: Southern Regional Station, ICAR - National Dairy Research Institute, Adugodi, Bengaluru - 560 030, Karnataka, India.
authors.forename: A
authors.initials: A
authors.lastname: Anantharaj
authors.affiliation: Southern Regional Station, ICAR - National Dairy Research Institute, Adugodi, Bengaluru - 560 030, Karnataka, India.
authors.forename: D N
authors.initials: DN
authors.lastname: Das
keywords: bovine uterine infections; cute phase proteins; negative energy balance; pro-inflammatory cytokines; transition period