title: Pneumatosis Coli in Complex Neurodisability: An Increasingly Problematic Disease Spectrum and Proposed Management.
abstract: This case series describes our experience in managing 4 children with complex neurodisability, feed intolerance, and pneumatosis coli. In all of the 4 patients, symptoms and feed tolerance were substantially improved by the formation of a laparoscopically assisted defunctioning ileostomy. We describe our present management strategy and believe this is a promising treatment for those patients who can reduce long-term dependence on parenteral nutrition, although we acknowledge that there is a long-term risk of disuse colitits in the defunctioned bowel.
authors.affiliation: *Paediatric Surgical Unit †Department of Neurology, Sheffield Children's National Health Service Trust ‡Department of Gastroenterology, Sheffield Children's Hospital, Sheffield, UK.
authors.forename: Rebecca
authors.initials: R
authors.lastname: West
authors.forename: Dipanker
authors.initials: D
authors.lastname: Dass
authors.forename: Santosh
authors.initials: S
authors.lastname: Mordekar
authors.forename: David
authors.initials: D
authors.lastname: Campbell
authors.forename: Richard
authors.initials: R
authors.lastname: Lindley
mesh_terms: D000293:Adolescent; D002648:Child; D004750:Enteral Nutrition; D005260:Female; D006801:Humans; D007081:Ileostomy; D010535:Laparoscopy; D009422:Nervous System Diseases / Q000150:complications*; D010288:Parenteral Nutrition; D011006:Pneumatosis Cystoides Intestinalis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy