title: [Factors associated with the surgical efficacy and prognosis of seizures in patients with low-grade glioma].
abstract: OBJECTIVE
  To explore the relevant factors associated with the surgical efficacy and prognosis of seizures in patients with low-grade glioma (LGG).
  
  
  METHODS
  The clinical cases of seizures in patients with LGG admitted to our department were retrospectively collected from January 2010 to December 2014. A total of 45 cases were studied to analyze the relevant factors associated with the surgical efficacy and prognosis.
  
  
  RESULTS
  During a follow-up period of 1 to 5 years after surgery, Engel classⅠ to Ⅱ were achieved in 36 patients (80%) and Engel class Ⅲ to Ⅳ in 9 cases (20%). The preoperative epilepsy frequency and the use of intraoperative electrocardiograph (ECoG) were correlated with the surgical efficacy and prognosis (P<0.05). The other factors, such as age, gender, duration of epilepsy, and tumor characteristics, had no significant statistical difference.
  
  
  CONCLUSIONS
  The surgical efficacy of seizures in patients with LGG is favorable. Our results suggest that preoperative epilepsy frequency and intraoperative ECoG are important factors for surgical efficacy and prognosis. Consequently, based on gross total resection for seizures in patients with LGG, epileptogenic zones should be considered and dealt with by use of ECoG.
authors.affiliation: Department of Neurosurgery, the First Affiliated Hospital of Fujian Medical University, Fuzhou 350005, China.
authors.forename: F
authors.initials: F
authors.lastname: Fang
authors.forename: Y X
authors.initials: YX
authors.lastname: Lin
authors.forename: D Z
authors.initials: DZ
authors.lastname: Kang
authors.forename: F
authors.initials: F
authors.lastname: Wang
authors.forename: X F
authors.initials: XF
authors.lastname: Huang
authors.forename: L H
authors.initials: LH
authors.lastname: Yu
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Lin
mesh_terms: D001932:Brain Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D004562:Electrocardiography; D004827:Epilepsy / Q000209:etiology / Q000601:surgery*; D005910:Glioma / Q000150:complications / Q000473:pathology* / Q000601:surgery*; D006801:Humans; D011379:Prognosis; D012189:Retrospective Studies; D012640:Seizures / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome