title: Surgical treatment of Peyronie's disease with small intestinal submucosa graft patch.
abstract: The objective of the study was to report our results using a porcine small intestinal submucosa graft (Surgisis ES, Cook Medical) for tunica albuginea substitution after plaque incision. We retrospectively evaluated patients surgically treated at our institution for Peyronie's disease (PD) by means of plaque incision and porcine small intestinal submucosa grafting (Surgisis) between 2009 and 2013. At the same time a literature review was conducted, searching for similar reports and results. Forty-four patients were identified who had been diagnosed with PD between 2009 and the beginning of 2013, and had been treated with corporoplasty, plaque incision and grafting with Surgisis for a severe curvature of the penis. Curvature of the penis was dorsal in 40 patients (90%) and laterally on the right in 4 patients (10%). Mean duration of surgery was 165 min (range 90-200). Mean size of the graft was 6.5 cm(2) and the mean follow-up was 19.2 months (range 11-48). In patients with severe curvature of the penis due to PD and the need for corporoplasty with plaque incision and graft placement, Surgisis represents a good option with a low risk of complications, below the rate described with previously investigated graft tissues.
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Cosentino
authors.affiliation: Urology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Kanashiro
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Vives
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Sanchez
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: M F
authors.initials: MF
authors.lastname: Peraza
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Moreno
authors.affiliation: Anesthesia Department, Hospital de la Santa Creu i Sant Pau, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Perona
authors.affiliation: Urology Department, Ospedale Borgo Trento, Verona, Italy.
authors.forename: V
authors.initials: V
authors.lastname: De Marco
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: E
authors.initials: E
authors.lastname: Ruiz-Castañe
authors.affiliation: Andrology Department, Fundació Puigvert, Universitat Autonoma de Barcelona, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Sarquella
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D007172:Erectile Dysfunction / Q000209:etiology / Q000601:surgery; D006801:Humans; D007413:Intestinal Mucosa / Q000637:transplantation*; D007421:Intestine, Small / Q000637:transplantation*; D008297:Male; D008875:Middle Aged; D010411:Penile Induration / Q000601:surgery*; D010413:Penis / Q000002:abnormalities / Q000601:surgery; D012189:Retrospective Studies; D013552:Swine; D014183:Transplantation, Heterologous / Q000379:methods*