title: Spatial Hotspot Analysis of Acute Myocardial Infarction Events in an Urban Population: A Correlation Study of Health Problems and Industrial Installation.
abstract: BACKGROUND
  The current study's objectives were to find any possible spatial patterns and hotspot of cardiovascular events and to perform a correlation study to find any possible relevance between cardiovascular disease (CVE) and location of industrial installation said above.
  
  
  METHODS
  We used the Acute Myocardial Infarction (AMI) hospital admission record in three main hospitals in Yazd, Yazd Province, Iran during 2013, because of CVDs and searched for possible correlation between industries as point-source pollutants and non-random distribution of AMI events.
  
  
  RESULTS
  MI incidence rate in Yazd was obtained 531 per 100,000 person-year among men, 458 per 100,000 person-year among women and 783/100,000 person-yr totally. We applied a GIS Hotspot analysis to determine feasible clusters and two sets of clusters were observed. Mean age of 56 AMI events occurred in the cluster cells was calculated as 62.21±14.75 yr. Age and sex as main confounders of AMI were evaluated in the cluster areas in comparison to other areas. We observed no significant difference regarding sex (59% in cluster cells versus 55% in total for men) and age (62.21±14.7 in cluster cells versus 63.28±13.98 in total for men).
  
  
  CONCLUSIONS
  We found proximity of AMI events cluster to industries installations, and a steel industry, specifically. There could be an association between road-related pollutants and the observed sets of cluster due to the proximity exist between rather crowded highways nearby the events cluster.
authors.affiliation: Dept. of Environmental Engineering, Yazd University, Yazd, Iran.
authors.forename: Motahareh Sadat
authors.initials: MS
authors.lastname: Namayande
authors.affiliation: Dept. of Environmental Engineering, Yazd University, Yazd, Iran.
authors.forename: Farhad
authors.initials: F
authors.lastname: Nejadkoorki
authors.affiliation: Yazd Cardiovascular Research Center, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
authors.forename: Seyedeh Mahdieh
authors.initials: SM
authors.lastname: Namayande
authors.affiliation: Dept. of Health Technology Assessment, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran.
authors.forename: Hamidreza
authors.initials: H
authors.lastname: Dehghan
keywords: Cardiac events; Correlation study; Geographical Information System; Hotspot; Industries