title: Pediatric Thromboembolism in Japan.
abstract: OBJECTIVE
  To investigate the clinical and epidemiologic characteristics of thromboembolism in Japanese children.
  
  
  METHODS
  Clinical data of 77 patients with thromboembolism from a national tertiary pediatric care center were reviewed.
  
  
  RESULTS
  Incidence of thromboembolism was calculated to be 15 per 10,000 hospital admissions. Infants younger than one year of age made up the largest age group (25 patients, including nine neonates younger than 30 d). The occurrence of thromboembolism increased over the years in the index population. Thromboembolism was diagnosed as follows: portal vein thrombosis (n = 15), obstruction of central venous catheter (n = 13) and cerebral infarction (n = 9). Among the 77 patients, there were eight mortalities and six significant sequelae.
  
  
  CONCLUSIONS
  In pediatric care, especially in intensive care, we should pay more attention to thromboembolism in order to detect it promptly.
authors.affiliation: Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan. ken-tetsuhara@mti.biglobe.ne.jp.|Division of Emergency Service and Transport Medicine, National Center for Child Health and Development, Tokyo, Japan. ken-tetsuhara@mti.biglobe.ne.jp.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Tetsuhara
authors.affiliation: Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan.|Division of Hematology, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Ishiguro
authors.affiliation: Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan.
authors.forename: Nobuaki
authors.initials: N
authors.lastname: Michihata
authors.affiliation: Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan.
authors.forename: Sonoko
authors.initials: S
authors.lastname: Sensaki
authors.affiliation: Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan.|Division of Hematology, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: Hisaya
authors.initials: H
authors.lastname: Nakadate
authors.affiliation: Department of General Pediatrics and Interdisciplinary Medicine, National Center for Child Health and Development, 2-10-1 Okura, Setagaya-ku, Tokyo, Japan.
authors.forename: Yui
authors.initials: Y
authors.lastname: Kimura
authors.affiliation: Division of Hematology, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Tomizawa
authors.affiliation: Division of Hematology, Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
authors.forename: Kimikazu
authors.initials: K
authors.lastname: Matsumoto
mesh_terms: D002648:Child; D002675:Child, Preschool; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D007564:Japan / Q000453:epidemiology; D012307:Risk Factors; D013923:Thromboembolism / Q000453:epidemiology*; D020246:Venous Thrombosis / Q000453:epidemiology*
keywords: Children; Epidemiology; Thromboembolism; Thrombophilia