title: Main Trunk and Division Middle Cerebral Artery Occlusions: Differences in Recanalization Times, Number of Stent Retriever Passes and Clinical Outcomes: A Single-Center Experience.
abstract: OBJECTIVE
  In this article, we present our experience with the recanalization of the middle cerebral artery (MCA), we hypothesize that there are higher rates of recanalization with fewer stent retriever passes and better clinical outcomes in patients with division MCA occlusions. A more complex anatomy at the bifurcation may prevent a faster recanalization in main trunk MCA occlusions.
  
  
  METHODS
  We retrospectively identified consecutive patients admitted with MCA occlusions who underwent mechanical thrombectomy using stent retrievers. We categorized patients into division MCA and main trunk MCA occlusions based on angiography. Variables were compared between the groups. We further analyzed patients with trunk MCA occlusions to identify reasons for delays in recanalization.
  
  
  RESULTS
  There were 32 MCA occlusions that underwent mechanical thrombectomy and eligible for the analysis during the study period. Of those, 11 were main trunk MCA occlusions. Univariate analysis disclosed a trend toward a lower GP-to-recanalization time (p = 0.05) and a lower number of passes required for recanalization in division MCA occlusions. However, there was a significantly better outcome in patients with division MCA occlusion after multivariate analysis. Analyzing main trunk MCA occlusion data, we found that the need for more than one pass to achieve recanalization led to a trend toward a longer GP-to-recanalization time and a worse outcome. When the stent was placed in the dominant division, the chances of recanalization were significantly higher.
  
  
  CONCLUSIONS
  Division MCA occlusions have higher recanalization rates with fewer stent retriever passes and better clinical outcomes than main trunk MCA occlusions, likely due to a more favorable anatomy. Measures like placing the stent retriever in the dominant division may decrease recanalization times and improve clinical outcomes in main trunk MCA occlusions.
authors.affiliation: Neurology Department, Texas Tech University Health Sciences Center, El Paso, Tex., USA.
authors.forename: Ihtesham A
authors.initials: IA
authors.lastname: Qureshi
authors.affiliation: Neurology Department, Texas Tech University Health Sciences Center, El Paso, Tex., USA.
authors.forename: Alberto
authors.initials: A
authors.lastname: Maud
authors.affiliation: Neurology Department, Texas Tech University Health Sciences Center, El Paso, Tex., USA.
authors.forename: Salvador
authors.initials: S
authors.lastname: Cruz-Flores
authors.affiliation: Neurology Department, Texas Tech University Health Sciences Center, El Paso, Tex., USA.
authors.forename: Gustavo J
authors.initials: GJ
authors.lastname: Rodriguez
keywords: Dominant division; Endovascular treatment; Main trunk; Middle cerebral artery; Recanalization; Stent retriever