title: Natural Killer Cell Lymphoma: A Case with Classification Dilemma.
abstract: Non-Hodgkins lymphoma of the Natural Killer (NK) cell type is rare. World Health Organisation recognises 3 NK-cell phenotypic entities; extranodal NK/T cell lymphoma, nasal type (ENK/TL); aggressive NK cell leukaemia (ANKL); and chronic lymphoproliferative disorders of NK cells (CLPD-NK) which is classified as a provisional entity. Though specific clinical, morphological and immunophenotypic criteria have been laid down to diagnose these conditions there may however, be considerable variations in the clinical presentation making diagnosis difficult. We present a case with contrasting clinical and haematopathological findings posing difficulty in its diagnosis and classification, and despite the aggressive presentation showing favourable response to treatment.
authors.affiliation: Senior Resident, Department of Pathology, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Ankit Kumar
authors.initials: AK
authors.lastname: Jitani
authors.affiliation: Associate Professor, Department of Pathology, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Yookarin
authors.initials: Y
authors.lastname: Khonglah
authors.affiliation: Assistant Professor, Department of Oncology, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Ritesh
authors.initials: R
authors.lastname: Kumar
authors.affiliation: Junior Resident, Department of Pathology, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Bidyut Bikash
authors.initials: BB
authors.lastname: Gogoi
authors.affiliation: Junior Resident, Department of Pathology, NEIGRIHMS , Shillong, Meghalaya, India .
authors.forename: Ekta
authors.initials: E
authors.lastname: Jajodia
keywords: Flow cytometry; NK-cell; Non-Hodgkins lymphoma