title: Anterior and posterior segment parameters measured with Fourier domain optical coherence tomography in photopic and scotopic conditions.
abstract: OBJECTIVE
  To compare anterior and posterior segment parameters measured with the iVue-100 optical coherence tomography (OCT) in photopic and scotopic conditions.
  
  
  METHODS
  Central and peripheral corneal thickness, retinal nerve fiber layer and macula thickness were measured using the iVue-100 OCT in 47 healthy individuals at a higher education institution in photopic (958 lux) and scotopic (0.03 lux) conditions.
  
  
  RESULTS
  As the lighting conditions changed from scotopic to photopic, a significant change in pupil size was noted (P < 0.001). However, there was no significant difference in central corneal thickness measurements with this change in surrounding illumination with only the temporal peripheral corneal area showing a significant difference (3.44 μm thinner). No significant differences were found in the retinal nerve fiber layer thickness. A significant decrease in the reading was noted in only the inferior (P = 0.05) and temporal (P = 0.05) inner macula area.
  
  
  CONCLUSIONS
  Change in the ambient lighting conditions does not result in a clinically significant difference in corneal, retinal nerve fiber layer, and macula thickness when measured with the iVue-100 OCT.
authors.forename: Nishanee
authors.initials: N
authors.lastname: Rampersad
authors.affiliation: Discipline of Optometry, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.
authors.forename: Rekha
authors.initials: R
authors.lastname: Hansraj
mesh_terms: D000293:Adolescent; D000328:Adult; D000869:Anterior Eye Segment / Q000033:anatomy & histology*; D055253:Color Vision / Q000502:physiology*; D003315:Cornea / Q000033:anatomy & histology; D003430:Cross-Sectional Studies; D005260:Female; D005583:Fourier Analysis; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D009412:Nerve Fibers; D055254:Night Vision / Q000502:physiology*; D057972:Posterior Eye Segment / Q000033:anatomy & histology*; D012165:Retinal Ganglion Cells / Q000166:cytology; D041623:Tomography, Optical Coherence; D055815:Young Adult