title: The impact of chorionicity and type of conception on maternal-neonatal outcome in twin pregnancies.
abstract: OBJECTIVE
  To evaluate the maternal and neonatal outcomes in twin pregnancies according to chorionicity (monochorionic (MC) versus dichorionic (DC) and type of conception [spontaneously conceived (SC) versus assisted reproduction technology (ART)].
  
  
  METHODS
  A retrospective study of 196 twin pregnancies admitted to the Department of Gynecology, Obstetrics and Urology of the University of Rome Sapienza, from January 2008 to April 2013.
  
  
  RESULTS
  There were 55 MC and 141 DC twin pregnancies (82 SC and 59 ART). MC twin pregnancies had a higher incidence of preterm birth (p < 0.008), twin-twin transfusion syndrome (TTTS) (p < 0.021), and intrauterine growth restriction (IUGR) (p < 0.05). MC pregnancies had lower neonatal birth weight (p < 0.05), and lower Apgar score. ART DC pregnancies had a higher incidence of preterm delivery (p < 0.05).
  
  
  CONCLUSIONS
  MC twin pregnancy is associated with higher risk of adverse maternal and perinatal outcomes. In the DC subgroup, ART is associated to a higher incidence of preterm delivery.
authors.forename: S
authors.initials: S
authors.lastname: D'Arpe
authors.forename: S
authors.initials: S
authors.lastname: Franceschetti
authors.forename: M G
authors.initials: MG
authors.lastname: De Stefano
authors.forename: R
authors.initials: R
authors.lastname: D'Amelio
authors.forename: A M
authors.initials: AM
authors.lastname: Maragno
authors.forename: M
authors.initials: M
authors.lastname: Candelieri
authors.forename: L
authors.initials: L
authors.lastname: Muzii
authors.forename: P
authors.initials: P
authors.lastname: Benedetti Panici
mesh_terms: D000328:Adult; D001034:Apgar Score; D002823:Chorion / Q000166:cytology*; D005260:Female; D005306:Fertilization; D005317:Fetal Growth Retardation / Q000175:diagnosis*; D005330:Fetofetal Transfusion / Q000175:diagnosis*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011256:Pregnancy Outcome; D059285:Pregnancy, Twin; D047928:Premature Birth; D012189:Retrospective Studies