title: [THE DIAGNOSTIC VALUE OF MODERN METHODS OF MICROBIOLOGICAL VERIFICATION OF COMMUNITY-ACQUIRED PNEUMONIA IN CLINICAL PRACTICE].
abstract: The study was carried out to determine etiological structure and informativeness of different methods of detection of agents of community-acquired pneumonia, the sampling included 274 examined patients aged from 16 to 80 years with community-acquired pneumonia of different degree of severity and being under hospital treatment. Besides of standard laboratory and clinical methods of examination ofpatients with community-acquired pneumonia special techniques of etiological verification were applied: molecular genetic analysis (polymerase chain reaction) of phlegm, qualitative detection of antigen Legionella pneumophila of serogroup 1 and antigen Streptococcus pneumoniae in samples of urine using quick immune chromatographic test, detection of level of serum specific immunoglobulines class M and G to Chlamidophilia pneumoniae, Mycoplasma pListeria monocytogenes in dynamics using immunoenzyme technique. The etiological structure of community-acquired pneumonia was established based of study results. The analysis of informativeness of different methods of etiological verification of diagnosis of community-acquired pneumonia demonstrated that combination ofpolymerase chain reaction and serological method is the optimal one.
authors.forename: G A
authors.initials: GA
authors.lastname: Mavzyutova
authors.forename: O Z
authors.initials: OZ
authors.lastname: Kuzovkina
authors.forename: I A
authors.initials: IA
authors.lastname: Mirsayapova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000907:Antibodies, Bacterial / Q000097:blood*; D016993:Chlamydophila pneumoniae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D017714:Community-Acquired Infections; D005260:Female; D006801:Humans; D007118:Immunoassay / Q000379:methods*; D007074:Immunoglobulin G / Q000097:blood; D007075:Immunoglobulin M / Q000097:blood; D016952:Legionella pneumophila / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D008089:Listeria monocytogenes / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D008297:Male; D008875:Middle Aged; D009093:Mucus / Q000382:microbiology; D009177:Mycoplasma pneumoniae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification; D018410:Pneumonia, Bacterial / Q000097:blood / Q000175:diagnosis*; D016133:Polymerase Chain Reaction / Q000379:methods*; D012703:Serotyping; D012720:Severity of Illness Index; D013296:Streptococcus pneumoniae / Q000235:genetics / Q000276:immunology / Q000302:isolation & purification
chemical_list: D000907:Antibodies, Bacterial; D007074:Immunoglobulin G; D007075:Immunoglobulin M