title: Feasibility and efficacy of a robotic device for hand rehabilitation in hemiplegic stroke patients: a randomized pilot controlled study.
abstract: OBJECTIVE
  The purpose of the study was to evaluate the feasibility and efficacy of robot-assisted hand rehabilitation in improving arm function abilities in sub-acute hemiplegic patients.
  
  
  METHODS
  Randomized controlled pilot study.
  
  
  METHODS
  Inpatient rehabilitation centers.
  
  
  METHODS
  Thirty hemiplegic stroke patients (Ashworth spasticity index <3) were recruited and randomly divided into a Treatment group (TG) and Control group (CG).
  
  
  METHODS
  Patients in the TG received intensive hand training with Gloreha, a hand rehabilitation glove that provides computer-controlled, repetitive, passive mobilization of the fingers, with multisensory feedback. Patients in the CG received the same amount of time in terms of conventional hand rehabilitation.
  
  
  METHODS
  Hand motor function (Motricity Index, MI), fine manual dexterity (Nine Hole Peg Test, NHPT) and strength (Grip and Pinch test) were measured at baseline and after rehabilitation, and the differences, (Δ) mean(standard deviation), compared between groups. Results Twenty-seven patients concluded the program: 14 in the TG and 13 in the CG. None of the patients refused the device and only one adverse event of rheumatoid arthritis reactivation was reported. Baseline data did not differ significantly between the two groups. In TG, ΔMI 23(16.4), ΔNHPT 0.16(0.16), ΔGRIP 0.27(0.23) and ΔPINCH 0.07(0.07) were significantly greater than in CG, ΔMI 5.2(9.2), ΔNHPT 0.02(0.07), ΔGRIP 0.03(0.06) and ΔPINCH 0.02(0.03)] ( p=0.002, p=0.009, p=0.003 and p=0.038, respectively).
  
  
  CONCLUSIONS
  Gloreha Professional is feasible and effective in recovering fine manual dexterity and strength and reducing arm disability in sub-acute hemiplegic patients.
authors.affiliation: 1 Neurological Rehabilitation Unit, Fondazione Salvatore Maugeri, IRCCS, Institute of Lumezzane, Brescia, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Vanoglio
authors.affiliation: 2 Care Continuity Unit, Fondazione Salvatore Maugeri, IRCCS, Institute of Lumezzane, Brescia, Italy.
authors.forename: Palmira
authors.initials: P
authors.lastname: Bernocchi
authors.affiliation: 3 Habilita Hospital, Sarnico, Bergamo, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Mulè
authors.affiliation: 1 Neurological Rehabilitation Unit, Fondazione Salvatore Maugeri, IRCCS, Institute of Lumezzane, Brescia, Italy.
authors.forename: Francesca
authors.initials: F
authors.lastname: Garofali
authors.affiliation: 1 Neurological Rehabilitation Unit, Fondazione Salvatore Maugeri, IRCCS, Institute of Lumezzane, Brescia, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Mora
authors.affiliation: 3 Habilita Hospital, Sarnico, Bergamo, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Taveggia
authors.affiliation: 2 Care Continuity Unit, Fondazione Salvatore Maugeri, IRCCS, Institute of Lumezzane, Brescia, Italy.
authors.forename: Simonetta
authors.initials: S
authors.lastname: Scalvini
authors.affiliation: 1 Neurological Rehabilitation Unit, Fondazione Salvatore Maugeri, IRCCS, Institute of Lumezzane, Brescia, Italy.
authors.forename: Alberto
authors.initials: A
authors.lastname: Luisa
mesh_terms: D000368:Aged; D005260:Female; D006225:Hand / Q000503:physiopathology*; D018737:Hand Strength / Q000502:physiology; D006429:Hemiplegia / Q000209:etiology / Q000503:physiopathology / Q000534:rehabilitation*; D006801:Humans; D007297:Inpatients; D007558:Italy; D008297:Male; D010865:Pilot Projects; D011446:Prospective Studies; D020127:Recovery of Function / Q000502:physiology*; D012047:Rehabilitation Centers; D012371:Robotics / Q000379:methods*; D020521:Stroke / Q000150:complications; D000071939:Stroke Rehabilitation / Q000379:methods*
keywords: Stroke; hand; rehabilitation; robotics