title: The association between dental health and nutritional status in chronic obstructive pulmonary disease.
abstract: Chronic obstructive pulmonary disease (COPD) and periodontitis are chronic inflammatory systemic diseases with common risk factors (smoking and aging). In COPD, poor periodontal health could result in inadequate nutrition, potentially causing loss of muscle volume. The purpose of this case-control study was to examine our hypothesis that COPD patients have poorer periodontal health and poorer nutritional status than non-COPD patients. Periodontal status was assessed using bleeding on probing (BOP), pocket depth (PD), and plaque-control ratio (PCR). Nutritional status was assessed using body mass index, lean body mass, and serum albumin levels. The COPD group ( n = 60) had fewer remaining teeth, greater BOP, greater PD, and lower serum albumin levels compared with smokers without COPD ( n = 41) and nonsmokers ( n = 35; p < 0.001). COPD was an independent risk factor for poor periodontal health, demonstrated by fewer remaining teeth (relative risk (RR), 5.48; p = 0.0024), BOP (RR, 12.8; p = 0.0009), and having >30% of remaining teeth with a PD ≥ 4 mm (RR, 4.82; p = 0.011). A significant negative correlation existed between the number of teeth with a PD ≥ 4 mm and serum albumin level ( r2= 0.127; p = 0.013). We demonstrated that poor periodontal health was associated with hypoalbuminemia, suggesting poor nutritional status and inflammation in COPD.
authors.affiliation: 1 Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Terashima
authors.affiliation: 1 Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Shotaro
authors.initials: S
authors.lastname: Chubachi
authors.affiliation: 1 Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Tatsu
authors.initials: T
authors.lastname: Matsuzaki
authors.affiliation: 1 Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakajima
authors.affiliation: 1 Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Minako
authors.initials: M
authors.lastname: Satoh
authors.affiliation: 1 Department of Respiratory Medicine, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Eri
authors.initials: E
authors.lastname: Iwami
authors.affiliation: 2 Department of Oral Medicine and Maxillofacial Surgery, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Kyouko
authors.initials: K
authors.lastname: Yoshida
authors.affiliation: 2 Department of Oral Medicine and Maxillofacial Surgery, Tokyo Dental College Ichikawa General Hospital, Ichikawa, Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Katakura
authors.affiliation: 3 Division of Pulmonary Medicine, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Betsuyaku
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D016022:Case-Control Studies; D003774:Dental Plaque Index; D005260:Female; D005541:Forced Expiratory Volume; D005888:Gingival Pocket / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009752:Nutritional Status; D009909:Oral Health; D010512:Periodontal Index; D010518:Periodontitis / Q000150:complications*; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications* / Q000503:physiopathology; D012307:Risk Factors; D012709:Serum Albumin / Q000378:metabolism; D012907:Smoking; D016388:Tooth Loss / Q000150:complications*
chemical_list: D012709:Serum Albumin
keywords: COPD; Periodontitis; bleeding on probing; hypoalbuminemia; pocket depth