title: [New possibilities will open up in human gene therapy].
abstract: Gene therapy is divided into somatic and germ line therapy. The latter involves reproductive cells or their stem cells, and its results are heritable. The effects of somatic gene therapy are generally restricted to a single tissue of the patient in question. Until now, all gene therapies in the world have belonged to the regime of somatic therapy, germ line therapy having been a theoretical possibility only. Very recently, however, a method has been developed which is applicable to germ line therapy as well. In addition to technical challenges, severe ethical problems are associated with germ line therapy, demanding opinion statement.
authors.forename: Petter
authors.initials: P
authors.lastname: Portin
mesh_terms: D004992:Ethics, Medical; D005788:Gene Pool; D005818:Genetic Engineering; D015316:Genetic Therapy / Q000941:ethics* / Q000639:trends*; D005854:Germ Cells; D006801:Humans