title: Comparison of Visceral Fat Measures with Cardiometabolic Risk Factors in Healthy Adults.
abstract: We aimed to evaluate the associations of visceral adiposity with cardiometabolic risk factors in normal subjects with integrated 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT). A total of 58 normal subjects who underwent 18F-FDG PET/CT scan for cancer screening were included in this study. Volume and average Hounsfield unit (HU) of visceral adipose tissue (VAT) was measured from CT components of integrated PET/CT. Standardized uptake values (SUVmax) of liver, spleen, lumbar spine and ascending aorta (AA) were measured from PET components of integrated PET/CT. Body mass index (coefficient 78.25, p = 0.0259), glucose (37.62, p<0.0001), insulin (348.90, p = 0.0011), logarithmic transformation of homeostatic model assessment index-insulin resistance (-2118.37, p = 0.0007), and VAT HU (-134.99, p<0.0001) were independently associated with VAT volume. Glucose (0.1187, p = 0.0098) and VAT volume (-0.004, p<0.0001) were found to be associated with VAT HU. Both VAT volume and VAT HU of whole abdominal cavity is significantly associated with cardiometabolic risk factors.
authors.affiliation: Department of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Kyoungjune
authors.initials: K
authors.lastname: Pak
authors.affiliation: Department of Family Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Seung Hun
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Family Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: Jeong Gyu
authors.initials: JG
authors.lastname: Lee
authors.affiliation: Department of Nuclear Medicine, Chung-Ang University College of Medicine, Seoul, Korea.
authors.forename: Ju Won
authors.initials: JW
authors.lastname: Seok
authors.affiliation: Department of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Korea.
authors.forename: In Joo
authors.initials: IJ
authors.lastname: Kim
mesh_terms: D050154:Adiposity; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D050152:Intra-Abdominal Fat / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged; D049268:Positron-Emission Tomography; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
chemical_list: D019788:Fluorodeoxyglucose F18