title: Evaluation of Acute Physiology and Chronic Health Evaluation II and sequential organ failure assessment scoring systems for prognostication of outcomes among Intensive Care Unit's patients.
abstract: BACKGROUND
  Acute Physiology and Chronic Health Evaluation II (APACHE II) and sequential organ failure assessment (SOFA) are of the most validated and prevalent general scoring systems over the world.
  
  
  OBJECTIVE
  The aim of the current study was to evaluate APACHE II and SOFA ability in predicting the outcomes (survivors, nonsurvivors) in surgical and medical Intensive Care Unit (ICU).
  
  
  METHODS
  This was an observational and prospective study of 300 consecutive patients admitted in surgical and medical ICU during a 6-month period.
  
  
  METHODS
  APACHE II and SOFA scores and demographic characteristics were recorded for each patient separately in the first admission 24 h.
  
  
  METHODS
  Receiver operator characteristic (ROC) curves, Hosmer-Lemeshow test, and logistic regression were used in the statistical analysis (95% confidence interval).
  
  
  RESULTS
  Data analysis showed a significant statistical difference in APACHE II and SOFA scores between survivor and nonsurvivor patients (P < 0.0001, P = 0.001; respectively). The discrimination power was acceptable for APACHE II and poor for SOFA (area under ROC [AUC] curve: 73.7% (standard error [SE]: 3.2%), 63.4% [SE: 3.6%]; respectively). The acceptable calibration was seen just for SOFA (χ(2) = 11.018, P = 0.051).
  
  
  CONCLUSIONS
  Both APACHE II and SOFA showed good predictive accuracy for results in surgical and medical ICUs; however, the SOFA is the choice to select, because of being simpler and easier to record data.
authors.affiliation: Faculty Member, Department of Nursing, North Khorasan University of Medical Sciences, North Khorasan Province, Iran.
authors.forename: M
authors.initials: M
authors.lastname: Hosseini
authors.affiliation: Faculty Member, Department of Nursing, Islamic Azad University, Bojnord, North Khorasan Province, Iran.
authors.forename: J
authors.initials: J
authors.lastname: Ramazani
keywords: Acute Physiology and Chronic Health Evaluation II; Intensive Care Unit; nonsurvivor; sequential organ failure assessment; survivor