title: Constituents of the Leaves of Pandanus utilis.
abstract: Nineteen compounds, including seven triterpenoids (1-7), five steroids (8-12), four cyclohexenone derivatives (13-16), two benzenoid glycosides (17 and 18) and one lignan (19), were isolated and separated from the leaves of Pandanus utilis through bioactivity-guided fractionation. Among them, one new lanosterol- type triterpenoid was found and named as (24R)-24-methyl-5a-4-demethyllanosta-9(11),25-dien-3β-ol (1). The structures of the isolates were determined by mass and spectroscopic analyses, and the compounds were subjected to anti-inflammatory, anti-oxidative and cytotoxic assays.
authors.forename: I-Wen
authors.initials: IW
authors.lastname: Loa
authors.forename: Yuan-Bin
authors.initials: YB
authors.lastname: Cheng
authors.forename: Chen-Chang
authors.initials: CC
authors.lastname: Haung
authors.forename: Tsong-Long
authors.initials: TL
authors.lastname: Hwang
authors.forename: Chin-Chung
authors.initials: CC
authors.lastname: Wu
authors.forename: Jing-Ru
authors.initials: JR
authors.lastname: Liou
authors.forename: Ming-Feng
authors.initials: MF
authors.lastname: Hou
authors.forename: Shyng-Shiou
authors.initials: SS
authors.lastname: Yuan
authors.forename: Fang-Rong
authors.initials: FR
authors.lastname: Chang
authors.forename: Yang-Chang
authors.initials: YC
authors.lastname: Wu
mesh_terms: D000893:Anti-Inflammatory Agents / Q000737:chemistry / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology; D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology; D045744:Cell Line, Tumor; D006027:Glycosides / Q000737:chemistry; D006801:Humans; D017705:Lignans / Q000737:chemistry; D008958:Models, Molecular; D015394:Molecular Structure; D031673:Pandanaceae / Q000737:chemistry*; D018515:Plant Leaves / Q000737:chemistry*; D013256:Steroids / Q000737:chemistry; D014315:Triterpenes / Q000737:chemistry
chemical_list: D000893:Anti-Inflammatory Agents; D000972:Antineoplastic Agents, Phytogenic; D000975:Antioxidants; D006027:Glycosides; D017705:Lignans; D013256:Steroids; D014315:Triterpenes