title: Solute-Solvent Interactions in Aqueous Solutions of Sulfobutyl Ether-β-cyclodextrin As Probed by UV-Raman and FTIR-ATR Analysis.
abstract: A vibrational study by means of UV-Raman and FTIR-ATR measurements has been performed on sulfobutyl ether β-cyclodextrin (SBE-β-CD)-water solutions, as a function of concentration and temperature, with the aim to provide a molecular-scale explanation of the enhanced performances as carrier agent exhibited by this modified macrocycle with respect to natural cyclodextrin. The attention has been mainly paid to the modifications induced on the vibrational band assigned to the O-H stretching intramolecular mode, in turn related to the dynamical rearrangement occurring in the hydrogen bonding (HB) network of water molecules. The results of our measurements clearly showed a characteristic "structure-breaker" effect on the tetrahedral HB arrangements induced on water molecules by increasing of both temperature and solute concentration, allowing us to also extract thermodynamic parameters. These results could be a key step for a clearer understanding of the connection between the dynamical properties of hydration water and the complexing ability of this cyclodextrin derivative.
authors.affiliation: Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Università degli Studi di Messina , viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
authors.forename: Valentina
authors.initials: V
authors.lastname: Venuti
authors.affiliation: Elettra - Sincrotrone Trieste , Strada Statale 14 km 163.5, Area Science Park, I-34149 Trieste, Italy.|Dipartimento di Fisica, Università degli Studi di Trento , via Sommarive 14, I-38123 Povo, Trento, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Rossi
authors.affiliation: Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Università degli Studi di Messina , viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
authors.forename: Vincenza
authors.initials: V
authors.lastname: Crupi
authors.affiliation: Elettra - Sincrotrone Trieste , Strada Statale 14 km 163.5, Area Science Park, I-34149 Trieste, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: D'Amico
authors.affiliation: Elettra - Sincrotrone Trieste , Strada Statale 14 km 163.5, Area Science Park, I-34149 Trieste, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Gessini
authors.affiliation: Dipartimento di Scienze Matematiche e Informatiche, Scienze Fisiche e Scienze della Terra, Università degli Studi di Messina , viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Majolino
authors.affiliation: Dipartimento di Fisica, Università degli Studi di Trento , via Sommarive 14, I-38123 Povo, Trento, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Masciovecchio
authors.affiliation: Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche e Ambientali, Università degli Studi di Messina , viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
authors.forename: Rosanna
authors.initials: R
authors.lastname: Stancanelli
authors.affiliation: Dipartimento di Scienze Chimiche, Biologiche, Farmaceutiche e Ambientali, Università degli Studi di Messina , viale Ferdinando Stagno D'Alcontres 31, 98166 Messina, Italy.
authors.forename: Cinzia Anna
authors.initials: CA
authors.lastname: Ventura