title: EnaBILEing Growth in the Fetal Liver.
abstract: Blood stem cells develop at successive sites in the vertebrate embryo, but the functional explanation for this behavior is unknown. Sigurdsson et al. (2016) provide justification for transient fetal liver residence, where select bile acid composition, derived from mother and embryo, provides a protective environment, enabling rapid stem cell expansion.
authors.affiliation: Genetics and Gastroenterology Divisions, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA; Gastrointestinal Cancer Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA. Electronic address: wgoessling@partners.org.
authors.forename: Wolfram
authors.initials: W
authors.lastname: Goessling
authors.affiliation: Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA; Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA. Electronic address: tnorth@bidmc.harvard.edu.
authors.forename: Trista E
authors.initials: TE
authors.lastname: North
mesh_terms: D008099:Liver