title: Application of Correlated Time-to-Event Models to Ecological Momentary Assessment Data.
abstract: Ecological momentary assessment data consist of in-the-moment sampling several times per day aimed at capturing phenomena that are highly variable. When research questions are focused on the association between a construct measured repeatedly and an event that occurs sporadically over time interspersed between repeated measures, the data consist of correlated observed or censored times to an event. In such a case, specialized time-to-event models that account for correlated observations are required to properly assess the relationships under study. In the current study, we apply two time-to-event analysis techniques, proportional hazards, and accelerated failure time modeling, to data from a study of affective states and sexual behavior in depressed adolescents and illustrate differing interpretations from the models.
authors.affiliation: Division of Biostatistics, Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, 1 Medical Center Drive, Lebanon, NH, 03766 , USA. emily.a.scherer@dartmouth.edu.
authors.forename: Emily A
authors.identifier: 0000-0002-6166-4455
authors.initials: EA
authors.lastname: Scherer
authors.affiliation: Clinical Research Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: Lin
authors.initials: L
authors.lastname: Huang
authors.affiliation: Clinical Research Center, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA.
authors.forename: Lydia A
authors.initials: LA
authors.lastname: Shrier
mesh_terms: D000293:Adolescent; D003627:Data Interpretation, Statistical; D003863:Depression; D000072860:Ecological Momentary Assessment; D005260:Female; D006801:Humans; D008297:Male; D015233:Models, Statistical; D016016:Proportional Hazards Models; D011594:Psychometrics; D012309:Risk-Taking; D012725:Sexual Behavior; D047568:Unsafe Sex
keywords: accelerated failure time model; ecological momentary assessment; proportional hazards model; time to event