title: Endoplasmic Stress Inhibitors for Homocysteine Induced Cardiovascular Disease.
abstract: Cardiovascular disease (CVD) remains a major cause of death and disability worldwide, thus preventing and inhibiting CVD remains a health priority. Several lines of pharmacological interventions have not met with great success, thus inhibition of novel cellular stress pathways could be a novel therapeutic avenue to treat CVD. This review will focus on homocysteine and endoplasmic reticulum stress linked to mitochondria function, and possible therapeutic avenues for treatment.
authors.affiliation: College of Health and Biomedicine, Victoria University, St. Albans, Autstralia. Anthony.Zulli@vu.edu.au.
authors.forename: Anthony
authors.initials: A
authors.lastname: Zulli
mesh_terms: D000818:Animals; D002318:Cardiovascular Diseases / Q000188:drug therapy* / Q000378:metabolism; D004721:Endoplasmic Reticulum / Q000187:drug effects* / Q000378:metabolism; D059865:Endoplasmic Reticulum Stress / Q000187:drug effects*; D006710:Homocysteine / Q000037:antagonists & inhibitors* / Q000378:metabolism; D006801:Humans; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism
chemical_list: D006710:Homocysteine