title: Recurrence rates and survival in a Danish cohort with renal cell carcinoma.
abstract: BACKGROUND
  Patients with localised and locally advanced renal cancer experience about 20% recurrence during a five-year follow-up period. The aim of the present study was to report recurrence rates and survival in a Danish population with renal cancer.
  
  
  METHODS
  Data on patients diagnosed with renal cell carcinoma (RCC) at our institute from January 2005 to December 2013 were collected retrospectively.
  
  
  RESULTS
  Overall, 367 patients were diagnosed with RCC during the period, and 78 patients (21%) presented with metastasis. The mean follow-up period for all patients was 41 months (standard deviation = 29, 95% confidence interval: 38-44). The total recurrence rates (RRs) at one, three and five years were 4.5%, 13.5% and 22.3%, respectively. Overall survival rates in the patients who underwent surgery with localised and locally advanced disease were 96.1%, 88.2% and 78.3% for one, three and five years, respectively. The mean time to first recurrence was 26.6 months. The one-year RR was 1.2%, 5.5% and 13.8% for low, intermediate and high-risk Leibovich scores, respectively. The three-year RR was 8.3%, 14.1% and 29.6% for low, intermediate and high-risk Leibovich scores, respectively; and the five-year RR was 12.0%, 26.6% and 52.9% for low, intermediate and high-risk Leibovich scores, respectively.
  
  
  CONCLUSIONS
  RRs after localised and locally advanced RCC was 22%. According to the risk of recurrence, we recommend a follow-up programme after nephrectomy with computed tomography every second year for low-risk patients, annually for intermediate-risk patients and every six months for high-risk patients.
  
  
  BACKGROUND
  none.
  
  
  BACKGROUND
  none.
authors.affiliation: azawinessn@gmail.com.
authors.forename: Nessn H
authors.initials: NH
authors.lastname: Azawi
authors.forename: Helen
authors.initials: H
authors.lastname: Tesfalem
authors.forename: Karina Sif Søndergaard
authors.initials: KS
authors.lastname: Mosholt
authors.forename: Peter
authors.initials: P
authors.lastname: Høyerup
authors.forename: Elisa Skovgaard
authors.initials: ES
authors.lastname: Jensen
authors.forename: Erik
authors.initials: E
authors.lastname: Malchau
authors.forename: Mikkel
authors.initials: M
authors.lastname: Fode
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002292:Carcinoma, Renal Cell / Q000175:diagnosis / Q000401:mortality*; D003718:Denmark / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009362:Neoplasm Metastasis / Q000175:diagnosis; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate