title: Short-Term Outcomes of Laparoscopic Distal Gastrectomy for Advanced Gastric Cancer.
abstract: The purpose of this study was to investigate the oncologic outcomes of laparoscopic distal gastrectomy (LDG) for advanced gastric cancer (AGC). Between April 2003 and March 2014, LDG was performed for 392 patients, 91 patients (23.2%) had histopathologically diagnosed AGC beyond T2 depth. The clinicopathological features, postoperative outcomes, mortality, morbidity, recurrence rate, and survivals of those patients were reviewed. The TNM stages of the tumor were IB in 26 patients (28.5%), IIA in 20 (21.9%), IIB in 18 (19.7%), IIIA in 13 (14.2%), IIIB in 6 (6.5%), IIIC in 6 (6.5%), and IV in 2 (2.1%). Major morbidity occurred in 14 patients (15.3%), with no postoperative mortality. Median follow-up was 24.5 months; 10 patients developed recurrence during the follow-up period, and 10 patients died, including 6 cancer deaths. The 5-year overall and disease-free survival rates were 76.8% and 72.6%, respectively. By stage, OS/DFS was 92.3%/91.8% in stage IB, 85.4%/85.4% in stage II, and 49.3%/26.9% in stage III. Oncologic outcomes were good in patients with AGC, especially with stage IB-IIB, who underwent LDG. LDG appears to be an effective approach for treating stage IB and II gastric cancer.
authors.affiliation: Department of Gastroenterological Surgery, Tokushima Red Cross Hospital.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Goto
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Okitsu
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Yuasa
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Kuramoto
authors.forename: Atsushi
authors.initials: A
authors.lastname: Tomibayashi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Matsumoto
authors.forename: Yuri
authors.initials: Y
authors.lastname: Masuda
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Edagawa
authors.forename: Ryotaro
authors.initials: R
authors.lastname: Tani
authors.forename: Osamu
authors.initials: O
authors.lastname: Mori
authors.forename: Yuta
authors.initials: Y
authors.lastname: Matsuo
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D005743:Gastrectomy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000209:etiology; D013274:Stomach Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome