title: The Rapid Effectiveness of Minocycline against Scrub Typhus Meningoencephalitis.
abstract: Scrub typhus is associated with various clinical symptoms. However, the pathogenesis of scrub typhus infection remains to be elucidated. A 73-year-old man was admitted to our hospital with consciousness disturbance and suspected meningoencephalitis. The patient's laboratory data showed deterioration and were indicative of hemophagocytic lymphohistiocytosis (HLH). A whole body examination to detect the trigger disease revealed an eschar, which is a characteristic of scrub typhus, on his back. His symptoms showed dramatic improvement after the administration of minocycline (MINO). This case report highlights that the clinical course of a case of scrub typhus meningoencephalitis that was cured with MINO.
authors.affiliation: Division of Neurology, Department of Internal Medicine, Shin-Oyama City Hospital, Japan.
authors.forename: Tameto
authors.initials: T
authors.lastname: Naoi
authors.forename: Haruo
authors.initials: H
authors.lastname: Shimazaki
authors.forename: Mikio
authors.initials: M
authors.lastname: Sawada
mesh_terms: D000368:Aged; D003937:Diagnosis, Differential; D006801:Humans; D051359:Lymphohistiocytosis, Hemophagocytic / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008911:Minocycline / Q000627:therapeutic use; D012612:Scrub Typhus / Q000150:complications* / Q000188:drug therapy
chemical_list: D008911:Minocycline