title: Cutaneous manifestation of gastrointestinal disease.
abstract: The gastrointestinal (GI) and cutaneous systems are closely linked in origin. Skin manifestations are frequently seen as a part of different GI syndromes. Gastroenterologists play an important role in recognizing the symptoms, patient workup and arriving at appropriate diagnoses, often in consultation with dermatologists. This review discusses the diseases with both cutaneous and intestinal involvement. Hereditary polyposis GI cancers, hereditary nonpolyposis colorectal cancers (CRCs), hamartomatous disorders, and inflammatory bowel disease (IBD) are reviewed with emphasis on the genetic basis, diagnostic, histologic findings, screening modalities, and therapeutic options.
authors.affiliation: Department of Pathology and Laboratory Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
authors.forename: Maral
authors.initials: M
authors.lastname: Rahvar
authors.affiliation: Department of Pathology and Laboratory Medicine, Loma Linda University Medical Center, Loma Linda, CA, USA.
authors.forename: Justin
authors.initials: J
authors.lastname: Kerstetter
keywords: Skin; hamartomatous disorders; hereditary nonpolyposis colorectal cancers (CRCs); hereditary polyposis gastrointestinal (GI) cancers; inflammatory bowel disease (IBD); intestine