title: Neuter No More: Fly Stem Cells Know Their Sex.
abstract: While sex differences in hormonal regulation of development and tissue maintenance are well established, the importance of genetic sex determination in adult lineages remains largely unexplored. Two studies now report that reversing the genetic sex of progenitors or differentiated cells in the fly intestine dramatically affects epithelial homeostasis and longevity.
authors.affiliation: Department of Biomedical Genetics, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA.
authors.forename: Douglas S
authors.initials: DS
authors.lastname: Portman
authors.affiliation: Department of Biomedical Genetics, School of Medicine and Dentistry, University of Rochester Medical Center, Rochester, NY 14642, USA. Electronic address: benoit_biteau@urmc.rochester.edu.
authors.forename: Benoît
authors.initials: B
authors.lastname: Biteau