title: Severe allergic-like contrast reactions: epidemiology and appropriate treatment.
abstract: Epinephrine is the most important treatment for severe allergic-like contrast reactions. The signs and symptoms of a severe reaction and the dose and methods of epinephrine administration are important for all radiologists to master. In this review article, we review the epidemiology of severe allergic-like contrast reactions, their common clinical manifestations, and their appropriate treatment, with a focus on correct epinephrine administration. We also discuss systematic limitations in the training of current and future radiologists, and recommend strategies for improvement.
authors.affiliation: Department of Radiology, Division of Abdominal Imaging, Massachusetts General Hospital, 55 Fruit Street, White 270, Boston, MA, 02114, USA. mascwill@med.umich.edu.
authors.forename: William R
authors.initials: WR
authors.lastname: Masch
authors.affiliation: Department of Radiology, Division of Abdominal Imaging, University of Washington, 1959 NE Pacific St., Seattle, WA, 98195, USA.
authors.forename: Carolyn L
authors.initials: CL
authors.lastname: Wang
authors.affiliation: Department of Radiology, Division of Abdominal Imaging, and Michigan Radiology Quality Collaborative, University of Michigan Health System, 1500 E. Medical Center Dr., Ann Arbor, MI, 48108, USA.
authors.forename: Matthew S
authors.initials: MS
authors.lastname: Davenport
mesh_terms: D000316:Adrenergic alpha-Agonists / Q000008:administration & dosage / Q000627:therapeutic use*; D003287:Contrast Media / Q000009:adverse effects*; D004305:Dose-Response Relationship, Drug; D004333:Drug Administration Routes; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D004837:Epinephrine / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D012307:Risk Factors
chemical_list: D000316:Adrenergic alpha-Agonists; D003287:Contrast Media; D004837:Epinephrine
keywords: Contrast media; Contrast reaction; Severe allergiclike reaction; Severe contrast reaction; Severe contrast reaction epidemiology; Severe contrast reaction treatment