title: Comparison of Two Different Sprint Interval Training Work-to-Rest Ratios on Acute Inflammatory Responses.
abstract: BACKGROUND
  The study aims to compare how work-to-rest ratio (W:R) influences insulin sensitivity (Si) and inflammatory responses following one session of sprint interval training (SIT).
  
  
  METHODS
  Thirteen men and two women completed a cross-over comparison of two SIT interventions-Tabata (TAB), 10 × 20-s sprints/10-s rest, and Wingate (WIN), 5 × 30-s sprints with 270-s rest. IL-6, IL-10, and TNF-α were assessed at baseline, immediately following, and 1 h after SIT, as well as prior to the 24-h post-exercise oral glucose tolerance tests (OGTTs).
  
  
  RESULTS
  Participants were 23.8 (±3.5) years old and 180.0 (±10.2) cm tall, weighed 78.5 (13.0) kg, and had 16.9 (±6.5) % body fat, with a mean VO2Peakof 42.0 (±7.9) ml kg-1min-1. There were no differences in total work (kJ) between TAB (64.7 ± 12.0) and WIN (68.0 ± 15.0). Mean (±95 % CI) Si24 h changed -2.8 (-5.1, -0.5) from baseline after TAB and -3.9 (-6.9, -0.9) after WIN. Cytokines were measured in pg ml-1and expressed as mean change (±95 % CI). IL-6 increased significantly immediately following SIT for TAB 0.70 (0.23, 1.17), and WIN 1.11 (0.60, 1.62), and remained elevated 1 h post SIT for TAB 1.10 (0.37, 1.83), and WIN 0.95 (0.26, 1.65). IL-10 showed a significant positive change immediately following exercise for TAB 1.53 (0.77, 2.29) and WIN 1.59 (0.58, 2.59). TNF-α also increased immediately both TAB 3.26 (1.57, 4.96) and WIN 3.05 (0.56, 5.54) and was directly proportional to IL-10 (r= 0.64,p< 0.0001).
  
  
  CONCLUSIONS
  W:R did not alter either the inflammatory or metabolic response following SIT nor does SIT improve 24-h Si, despite increased levels of IL-10.
authors.affiliation: Department of Health and Human Performance, Ferrum College, Ferrum, VA 24088 USA.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Harnish
authors.affiliation: Department of Biostatistics, Virginia Commonwealth University, Richmond, VA 23298 USA.
authors.forename: Roy T
authors.initials: RT
authors.lastname: Sabo
keywords: Cytokines; Myokines; SIT; Tabata; Wingate