title: Transient Deformation of Neutrophils in Kawasaki Disease.
abstract: In the treatment of Kawasaki disease, resistance to high-dose immunoglobulin intravenous (IGIV) can occur. The neutrophil morphology analyses in 17 patients revealed that transient pseudo-Pelger-Huët anomaly was more frequently detected in the IGIV-resistant group. This finding may aid the prediction of IGIV resistance.
authors.affiliation: Department of General Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Yumi
authors.initials: Y
authors.lastname: Koike
authors.affiliation: Department of Hematology/Oncology, Nagano Children's Hospital, Azumino, Japan; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan. Electronic address: ryu@shinshu-u.ac.jp.
authors.forename: Ryu
authors.initials: R
authors.lastname: Yanagisawa
authors.affiliation: Department of Clinical Pathology, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Yoshifumi
authors.initials: Y
authors.lastname: Ogiso
authors.affiliation: Department of General Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Cho
authors.affiliation: Department of General Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Kisei
authors.initials: K
authors.lastname: Minami
authors.affiliation: Department of General Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Takeuchi
authors.affiliation: Department of Hematology/Oncology, Nagano Children's Hospital, Azumino, Japan; Department of Pediatrics, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Sakashita
authors.affiliation: Department of General Pediatrics, Nagano Children's Hospital, Azumino, Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Higuchi
mesh_terms: D002675:Child, Preschool; D004351:Drug Resistance; D005260:Female; D006801:Humans; D016756:Immunoglobulins, Intravenous / Q000627:therapeutic use*; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000188:drug therapy*; D010381:Pelger-Huet Anomaly / Q000150:complications / Q000175:diagnosis*; D012189:Retrospective Studies
chemical_list: D016756:Immunoglobulins, Intravenous
keywords: Coronary artery lesion; High-dose intravenous immunoglobulin; Kawasaki disease; Mucocutaneous lymph node syndrome; Pseudo-Pelger‐Huët anomaly