title: Magnetic nanoparticles: preparation methods, applications in cancer diagnosis and cancer therapy.
abstract: Super-paramagnetic iron oxide nanoparticles (SPIONs) have been widely explored as novel magnetic resonance imaging (MRI) contrast agents because of a combination of favorable super-paramagnetic properties, biodegradability, and surface properties. Among the numerous MNPs under examination, SPIONs have involved considerable interest due to their outstanding magnetic properties, biocompatibility, and biodegradability. This review debates the ABCs of MR imaging, reports and informs the state of the art of magnetic nanoparticles in cancer dealing the source of SPIONs' exclusive magnetic properties, recent progresses in MRI acquisition methods for detection of SPIONs.
authors.affiliation: a Faculty of Medicine , Islamic Azad University Tabriz Branch , Tabriz , Iran.
authors.forename: Saeid
authors.initials: S
authors.lastname: Shabestari Khiabani
authors.affiliation: b Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences , Tabriz University of Medical Sciences , Tabriz , Iran.|c Student Research Committee , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Farshbaf
authors.affiliation: a Faculty of Medicine , Islamic Azad University Tabriz Branch , Tabriz , Iran.|b Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences , Tabriz University of Medical Sciences , Tabriz , Iran.|d Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Akbarzadeh
authors.affiliation: b Department of Medical Nanotechnology, Faculty of Advanced Medical Sciences , Tabriz University of Medical Sciences , Tabriz , Iran.|d Drug Applied Research Center , Tabriz University of Medical Sciences , Tabriz , Iran.
authors.forename: Soodabeh
authors.initials: S
authors.lastname: Davaran
mesh_terms: D000818:Animals; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use*; D009369:Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy*
chemical_list: D058185:Magnetite Nanoparticles
keywords: Biocompatibility; MRI; SPIONs; magnetic nanoparticles