title: Rickettsia massiliae infection and SENLAT syndrome in Romania.
abstract: The purpose of this prospective study is to describe the clinical and epidemiological characteristics of rickettsioses in Romania, where only Rickettsia conorii is known by clinicians but new Rickettsia species have been identified recently in ticks. A total of eight patients, including a nine-year-old child, were included between June 2011 and June 2012, in the Hospital for Infectious and Tropical Diseases, Bucharest, Romania. Seven cases presented during summer months and one in spring. Six patients presented a generalized rash with fever, myalgia and skin eschar. The last two patients presented a typical SENLAT syndrome, characterized by scalp eschar and neck lymphadenopathy. Using serological tools, we confirmed for the first time two cases of Rickettsia massiliae, the agent of spotted fever disease, and one case of Rickettsia slovaca, and one case of R. slovacaRickettsia raoultii the agents of SENLAT syndrome.
authors.affiliation: Dr. Victor Babes Clinical Hospital for Infectious and Tropical Diseases, Bucharest, Romania.
authors.forename: Mihaela
authors.initials: M
authors.lastname: Zaharia
authors.affiliation: Dr. Victor Babes Clinical Hospital for Infectious and Tropical Diseases, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Romania.
authors.forename: Corneliu Petru
authors.initials: CP
authors.lastname: Popescu
authors.affiliation: Dr. Victor Babes Clinical Hospital for Infectious and Tropical Diseases, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Romania.
authors.forename: Simin Aysel
authors.initials: SA
authors.lastname: Florescu
authors.affiliation: Dr. Victor Babes Clinical Hospital for Infectious and Tropical Diseases, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania, Romania.
authors.forename: Emanoil
authors.initials: E
authors.lastname: Ceausu
authors.affiliation: Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, 13005 Marseille, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Raoult
authors.affiliation: Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, 13005 Marseille, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Parola
authors.affiliation: Aix Marseille Université, URMITE, UM63, CNRS 7278, IRD 198, Inserm 1095, 13005 Marseille, France. Electronic address: cr_socolovschi@yahoo.com.
authors.forename: Cristina
authors.initials: C
authors.lastname: Socolovschi
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D002648:Child; D005260:Female; D006801:Humans; D000072281:Lymphadenopathy / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D012281:Rickettsia / Q000145:classification* / Q000302:isolation & purification; D012282:Rickettsia Infections / Q000097:blood / Q000453:epidemiology / Q000382:microbiology*; D020114:Rickettsia conorii / Q000302:isolation & purification; D012383:Romania / Q000453:epidemiology; D013577:Syndrome; D017282:Tick-Borne Diseases / Q000453:epidemiology* / Q000382:microbiology; D013987:Ticks / Q000382:microbiology
keywords: Rickettsia massiliae; Rickettsia raoultii; Rickettsia slovaca; Rickettsioses; Romania; Tick