title: Access to Isoquinolines and Isoquinolin-3-ols via Rh(III)-Catalyzed Coupling/Cyclization Cascade Reaction of Arylimidates and Diazo Compounds.
abstract: A Rh(III)-catalyzed coupling/cyclization cascade reaction is described, which involves arylimidates and diazo compounds and proceeds via intermolecular C-C bond formation and subsequent intramolecular C-N bond formation. Mechanistic investigation revealed that the reaction is a two-step process: the initial Rh(III)-catalyzed coupling/cyclization proceeds very fast and the following dehydration is rather slow. The reaction provides a direct approach to isoquinolines and isoquinolin-3-ols without any oxidants.
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai 200237, China.
authors.forename: Xing Guang
authors.initials: XG
authors.lastname: Li
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai 200237, China.
authors.forename: Min
authors.initials: M
authors.lastname: Sun
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai 200237, China.
authors.forename: Qiao
authors.initials: Q
authors.lastname: Jin
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai 200237, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Liu
authors.affiliation: Shanghai Key Laboratory of Functional Materials Chemistry, Key Lab for Advanced Materials and Institute of Fine Chemicals, East China University of Science and Technology , Meilong Road 130, Shanghai 200237, China.
authors.forename: Pei Nian
authors.initials: PN
authors.lastname: Liu