title: Crohn's Disease of the Ileoanal Pouch.
abstract: Crohn's disease (CD) of the pouch is an increasingly recognized diagnosis after ileal pouch-anal anastomosis. This post-ileal pouch-anal anastomosis diagnosis in conjunction with pouchitis remains the leading reason for pouch excision. Unfortunately, CD of the pouch remains a difficult diagnosis with lack of a uniform definition largely because of its similarity to common postoperative pouch complications, including pouchitis, abscess formation, or stricture at the anastomosis. Once diagnosed, treatment algorithms largely include multimodal therapy including biologics. This review focuses on the definition, etiology, diagnosis, and treatment for CD of the pouch, a postoperative de novo diagnosis of CD.
authors.affiliation: *Division of Colon and Rectal Surgery, Mayo Clinic, Rochester, Minnesota; and †Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota.
authors.forename: Amy L
authors.initials: AL
authors.lastname: Lightner
authors.forename: John H
authors.initials: JH
authors.lastname: Pemberton
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Loftus
mesh_terms: D003093:Colitis, Ulcerative / Q000601:surgery; D039021:Colonic Pouches; D003424:Crohn Disease / Q000175:diagnosis* / Q000209:etiology / Q000601:surgery / Q000628:therapy*; D003937:Diagnosis, Differential; D006801:Humans; D011183:Postoperative Complications / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy*; D016737:Proctocolectomy, Restorative / Q000009:adverse effects*; D012307:Risk Factors