title: [A clinical case of combined treatment of a patient with breast cancer and metastases to the brain and meninges].
abstract: The article describes a clinical case of successful chemotherapeutic and radiation treatment of a patient with breast cancer and metastases to the brain and meninges and with a pronounced neurological deficit. The patient underwent combined treatment (whole brain radiation with TBD of 30 Gy and local radiation of a metastasis with TBD of 15 Gy associated with capecitabine therapy) with continued administration of capecitabine until improvement. A partial metastasis reduction by 50% and complete regression of the neurological deficit were observed. Disease-free period was 1 year and 10 months, and the overall survival amounted to 2 years.
authors.affiliation: Department of Oncological Neurosurgery, Blokhin Russian Cancer Research Center, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Moskvina
authors.affiliation: Department of Oncological Neurosurgery, Blokhin Russian Cancer Research Center, Moscow, Russia.
authors.forename: D R
authors.initials: DR
authors.lastname: Naskhletashvili
authors.affiliation: Department of Oncological Neurosurgery, Blokhin Russian Cancer Research Center, Moscow, Russia.
authors.forename: A Kh
authors.initials: AK
authors.lastname: Bekyashev
authors.affiliation: Department of Oncological Neurosurgery, Blokhin Russian Cancer Research Center, Moscow, Russia.
authors.forename: S V
authors.initials: SV
authors.lastname: Medvedev
authors.affiliation: Department of Oncological Neurosurgery, Blokhin Russian Cancer Research Center, Moscow, Russia.
authors.forename: D M
authors.initials: DM
authors.lastname: Belov
authors.affiliation: Department of Oncological Neurosurgery, Blokhin Russian Cancer Research Center, Moscow, Russia.
authors.forename: T G
authors.initials: TG
authors.lastname: Gasparyan
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000473:pathology / Q000556:secondary / Q000628:therapy; D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy; D000069287:Capecitabine / Q000008:administration & dosage*; D059248:Chemoradiotherapy; D005260:Female; D006801:Humans; D008577:Meningeal Neoplasms / Q000473:pathology / Q000556:secondary / Q000628:therapy; D009362:Neoplasm Metastasis
chemical_list: D000069287:Capecitabine