title: Weight Regain Following Sleeve Gastrectomy-a Systematic Review.
abstract: Sleeve gastrectomy (SG) is a commonly performed bariatric procedure. Weight regain following SG is a significant issue. Yet the defining, reporting and understanding of this phenomenon remains largely neglected. Systematic review was performed to locate articles reporting the definition, rate and/or cause of weight regain in patients at least 2 years post-SG. A range of definitions employed to describe weight regain were identified in the literature. Rates of regain ranged from 5.7 % at 2 years to 75.6 % at 6 years. Proposed causes of weight regain included initial sleeve size, sleeve dilation, increased ghrelin levels, inadequate follow-up support and maladaptive lifestyle behaviours. Bariatric literature would benefit from standardising definitions used to report weight regain and its rate in clinical series. Larger prospective studies are required to further understand mechanisms of weight regain following SG.
authors.affiliation: Department of Surgery, South Auckland Clinical Campus, University of Auckland, Auckland, New Zealand. m.lauti@auckland.ac.nz.
authors.forename: Melanie
authors.initials: M
authors.lastname: Lauti
authors.affiliation: Department of Surgery, South Auckland Clinical Campus, University of Auckland, Auckland, New Zealand.
authors.forename: Malsha
authors.initials: M
authors.lastname: Kularatna
authors.affiliation: Department of Surgery, South Auckland Clinical Campus, University of Auckland, Auckland, New Zealand.
authors.forename: Andrew G
authors.initials: AG
authors.lastname: Hill
authors.affiliation: Department of Surgery, South Auckland Clinical Campus, University of Auckland, Auckland, New Zealand.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: MacCormick
mesh_terms: D050110:Bariatric Surgery / Q000295:instrumentation / Q000379:methods*; D005743:Gastrectomy / Q000295:instrumentation / Q000379:methods*; D054439:Ghrelin / Q000097:blood; D006801:Humans; D008019:Life Style; D008134:Long-Term Care / Q000379:methods / Q000592:standards; D009767:Obesity, Morbid / Q000097:blood / Q000503:physiopathology / Q000601:surgery*; D011446:Prospective Studies; D012008:Recurrence; D015430:Weight Gain / Q000502:physiology*
chemical_list: D054439:Ghrelin
keywords: Bariatric surgery; Sleeve gastrectomy; Weight regain