title: Synthesis of 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles by the reaction of indoline-2,3-diones with difluoromethylene phosphabetaine.
abstract: An unprecedent reaction of indoline-2,3-diones and (triphenylphosphonio)difluoroacetate (PDFA) afforded novel 3-fluoroalkenyl-3-trifluoromethyl-2-oxindoles in moderate to excellent yields. These products could be transformed into other trifluoromethylated oxindole derivatives.
authors.affiliation: School of Chemistry and Pharmaceutical Engineering, Sichuan University of Science & Engineering, 180 Xueyuan Street, Huixing Lu, Zigong, Sichuan 643000, China. liuyingleyou@163.com.
authors.forename: Yingle
authors.initials: Y
authors.lastname: Liu
authors.forename: Ke
authors.initials: K
authors.lastname: Zhang
authors.forename: Yangen
authors.initials: Y
authors.lastname: Huang
authors.forename: Shen
authors.initials: S
authors.lastname: Pan
authors.forename: Xiao-Qiang
authors.initials: XQ
authors.lastname: Liu
authors.forename: Yi
authors.initials: Y
authors.lastname: Yang
authors.forename: Yan
authors.initials: Y
authors.lastname: Jiang
authors.forename: Xiu-Hua
authors.initials: XH
authors.lastname: Xu
mesh_terms: D001622:Betaine / Q000031:analogs & derivatives* / Q000737:chemistry; D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D000078183:Oxindoles
chemical_list: D007211:Indoles; D000078183:Oxindoles; C000613168:difluoromethylene phosphabetaine; C572590:indoline-2,3-dione; C022960:2-oxindole; D001622:Betaine