title: Arabidopsis atypical kinase ABC1K1 is involved in red light-mediated development.
abstract: ABC1K1 functions as a novel negative regulator downstream of phyB and HY5 in red light-mediated Arabidopsis development. Light is a key environmental factor for plant morphogenesis. To understand the role of ACTIVITY OF BC1 COMPLEX KINASE (ABC1K) family members in light-mediated Arabidopsis development, we examined the phenotype of abc1k mutants under various light conditions. We show that abc1k1 mutants display significantly short hypocotyls specifically under continuous red light and this effect is more apparent under higher red light fluence rates. The expression of PHYTOCHROME-INTERACTING FACTORs (PIFs), transcription factors in red light signaling, is repressed in abc1k1 mutants under continuous red light. The expression pattern of ABC1K1 is independent of light conditions. Furthermore, genetic analysis indicates that abc1k1 almost completely suppresses the long hypocotyl phenotype of phyB and hy5. However, the mutation of ABC1K3, one homolog of ABC1K1, reverses the inhibition of hypocotyl elongation in phyB and hy5 by abc1k1. Together, our research describes novel characteristics for ABC1K1 in seedling stage and defines it as a novel negative component in red light-mediated Arabidopsis development.
authors.affiliation: State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Advanced Agriculture Sciences and School of Life Sciences, Peking University, Beijing, 100871, China.
authors.forename: Mei
authors.initials: M
authors.lastname: Yang
authors.affiliation: School of Life Sciences and School of Medicine, Tsinghua University, Beijing, 100084, China.
authors.forename: Hao
authors.initials: H
authors.lastname: Huang
authors.affiliation: State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100094, China.
authors.forename: Caiguo
authors.initials: C
authors.lastname: Zhang
authors.affiliation: State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100094, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Botany, College of Life Sciences, Hunan Normal University, Changsha, 410081, China.
authors.forename: Yan'e
authors.initials: Y
authors.lastname: Su
authors.affiliation: State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Advanced Agriculture Sciences and School of Life Sciences, Peking University, Beijing, 100871, China.
authors.forename: Pan
authors.initials: P
authors.lastname: Zhu
authors.affiliation: State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing, 100094, China. guoyan@cau.edu.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Protein and Plant Gene Research, Peking-Tsinghua Center for Life Sciences, School of Advanced Agriculture Sciences and School of Life Sciences, Peking University, Beijing, 100871, China. deng@pku.edu.cn.
authors.forename: Xing Wang
authors.initials: XW
authors.lastname: Deng
mesh_terms: D017360:Arabidopsis / Q000201:enzymology / Q000254:growth & development* / Q000528:radiation effects; D029681:Arabidopsis Proteins / Q000502:physiology*; D018506:Gene Expression Regulation, Plant / Q000187:drug effects / Q000502:physiology; D018546:Hypocotyl / Q000254:growth & development; D008027:Light; D009154:Mutation; D016133:Polymerase Chain Reaction; D011494:Protein Kinases / Q000502:physiology*; D017346:Protein Serine-Threonine Kinases; D036226:Seedlings / Q000254:growth & development / Q000528:radiation effects; D014157:Transcription Factors
chemical_list: D029681:Arabidopsis Proteins; D014157:Transcription Factors; D011494:Protein Kinases; C000604980:ABC1K1 protein, Arabidopsis; D017346:Protein Serine-Threonine Kinases
keywords: ABC1 kinase; Arabidopsis; HY5; Hypocotyl; Light signaling; phyB