title: Chromo-fluorogenic probes for carbon monoxide detection.
abstract: The sensing of carbon monoxide (CO) using electrochemical cells or semiconducting metal oxides has led to inexpensive alarms for the home and workplace. It is now recognised that chronic exposure to low levels of CO also poses a significant health risk. It is perhaps surprising therefore that the CO is used in cell-signalling pathways and plays a growing role in therapy. However, the selective monitoring of low levels of CO remains challenging, and it is this area that has benefited from the development of probes which give a colour or fluorescence response. This feature article covers the design of chromo-fluorogenic probes and their application to CO sensing in air, solution and in cells.
authors.affiliation: Instituto Interuniversitario de Investigación de Reconocimiento Molecular y Desarrollo Tecnológico (IDM), Unidad Mixta Universidad Politécnica de Valencia-Universidad de Valencia, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Marín-Hernández
authors.forename: Anita
authors.initials: A
authors.lastname: Toscani
authors.forename: Félix
authors.initials: F
authors.lastname: Sancenón
authors.forename: James D E T
authors.initials: JD
authors.lastname: Wilton-Ely
authors.forename: Ramón
authors.initials: R
authors.lastname: Martínez-Máñez
mesh_terms: D002248:Carbon Monoxide / Q000032:analysis* / Q000737:chemistry*; D002623:Chemistry Techniques, Analytical / Q000295:instrumentation*; D003116:Color; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans
chemical_list: D005456:Fluorescent Dyes; D002248:Carbon Monoxide