title: Approximate Entropy of Respiratory Movements in Human Newborns during Different Sleep States.
abstract: Previous studies have reported that the respiratory cycle of healthy newborns is more irregular during active sleep. This study aimed to apply non-linear analysis to examine the irregularity of respiratory movement in newborns at different sleep states. The respiratory movement signals from an abdominal band during quiet and active sleep were analyzed using approximate entropy (ApEn). The breathing interval of active sleep was significantly shorter than that of quiet sleep [1.30 (0.17) s vs. 1.58 (0.11) s; (P < 0.03)]. The ApEn of respiratory movements during active sleep were significantly larger than that during quiet sleep [0.785 (0.135) s vs. 0.678 (0.083) s; (P < 0.05)]. We found that the ApEn of respiratory movement in healthy newborns could detect irregularities in respiration during sleep.
authors.affiliation: Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Hiroo
authors.initials: H
authors.lastname: Tamaki
authors.affiliation: †Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Mazumi
authors.initials: M
authors.lastname: Miura
authors.affiliation: Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Sachiko
authors.initials: S
authors.lastname: Nakamoto
authors.affiliation: Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Horie
authors.affiliation: †Division of Pediatrics and Perinatology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Susumu
authors.initials: S
authors.lastname: Kanzaki
authors.affiliation: ‡Division of Medical Oncology and Molecular Respirology, Department of Multidisciplinary Internal Medicine, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Shimizu
authors.affiliation: §Department of Biological Regulation, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Amisaki
authors.affiliation: Department of Pathobiological Science and Technology, School of Health Science, Tottori University Faculty of Medicine, Yonago 683-8503, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Burioka
keywords: active sleep; approximate entropy; newborn; quiet sleep; respiration