title: Two cases of ultrathin Descemet stripping automated endothelial keratoplasty utilizing a graft that had undergone radial keratotomy.
abstract: This is a report of two cases in which tissue that had undergone radial keratotomy (RK) was utilized for double-pass ultrathin Descemet stripping automated endothelial keratoplasty (UT-DSAEK). Postoperative slit-lamp examination, visual acuity, anterior segment optical coherence tomography, and specular microscopy were available 30 months after surgery. Both corneas from a donor, who had undergone RK several years before his demise, and were otherwise suitable for endothelial keratoplasty were prepared for UT-DSAEK using double-pass dissection using first a 300 mm microkeratome head and then a 130μm microkeratome head (ALTK system, Moria, Antony, France). After the second cut, the tissue was punched to 9.0 mm and transplanted in two eyes with endothelial decompensation according to standard technique. As early as 3 months after surgery, both patients had 20/25 best-corrected visual acuity, which remained stable for the following 27 months. Postoperative endothelial cell loss was 34% and 57% at 2.5 years. In conclusion, post-RK donor tissue can be used for UT-DSAEK.
authors.forename: Yoav
authors.initials: Y
authors.lastname: Nahum
authors.forename: Diego
authors.initials: D
authors.lastname: Ponzin
authors.affiliation: Department of Ophthalmology, Villa Igea Hospital, Forlì; Istituto Internazionale per la Ricerca e Formazione in Oftalmologia, Forlì,, Italy.
authors.forename: Massimo
authors.initials: M
authors.lastname: Busin
mesh_terms: D000328:Adult; D002452:Cell Count; D057111:Descemet Stripping Endothelial Keratoplasty / Q000379:methods*; D004728:Endothelium, Corneal / Q000033:anatomy & histology* / Q000637:transplantation; D005260:Female; D005642:Fuchs' Endothelial Dystrophy / Q000601:surgery; D006084:Graft Rejection / Q000601:surgery; D006085:Graft Survival; D006801:Humans; D007646:Keratotomy, Radial; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D012189:Retrospective Studies; D014019:Tissue Donors; D041623:Tomography, Optical Coherence; D066027:Transplant Recipients; D014792:Visual Acuity