title: Effects of sodium ferrous chlorophyll treatment on anemia of hemodialysis patients and relevant biochemical parameters.
abstract: This study explores the effects of sodium ferrous chlorophyll treatment on the anemia of maintenance hemodialysis (MHD) patients, as well as the relevant biochemical parameters. We selected 72 patients who had received regular MHD treatment two or three times a week for more than 3 months in the Hospital of Traditional Chinese Medicine of Zhengzhou City of Henan Province from March 2014 to March 2016. They were equally divided into a treatment group and a control group. Haemoglobin (HB) and hematocrit (HCT) of the treatment group increased significantly after treatment (p < 0.01), but less in the control group (p < 0.05); Also serum ferritin (SF) and transferrin saturation (TAST) of the treatment group increased significantly after treatment (p < 0.01); SF of the control group also increased significantly (p < 0.01) and TAST of the control group increased (p < 0.05) but less than in the treatment group. No obvious changes of serum creatinine (SCR), blood urea nitrogen (BUN), C-reactive protein (CRP) and superoxide dismutase (SOD) were found in either groups after treatment (p>0.05). Albumin (ALB) dosage of the treatment group increased after treatment (p < 0.05) while hemopoietin (EPO) decreased significantly (p < 0.01). ALB and EPO of the control group had no obvious changes after treatment (p>0.05). ALB level of the treatment group increased more significantly than in the control group (p < 0.05), while EPO dosage decreased more significantly than in the control group (p <0.05). Therefore, the combination of conventional western medicine and sodium ferrous chlorophyll can effectively improve anemia conditions of MHD patients and their quality of life.
authors.affiliation: Nephrology Division, Zhengzhou TCM Hospital, Zhengzhou, China.
authors.forename: X F
authors.initials: XF
authors.lastname: Xu
authors.affiliation: Nephrology Division, Zhengzhou TCM Hospital, Zhengzhou, China.
authors.forename: J P
authors.initials: JP
authors.lastname: Hu
authors.affiliation: Nephrology Division, Zhengzhou TCM Hospital, Zhengzhou, China.
authors.forename: X
authors.initials: X
authors.lastname: Cheng
authors.affiliation: Nephrology Division, Affiliated Hospital, Henan Province, Chinese Medicine Research Institute, Zhengzhou, China.
authors.forename: G J
authors.initials: GJ
authors.lastname: Yu
authors.affiliation: Endocrinology Division, Zhengzhou Central Hospital, Zhengzhou, China.
authors.forename: F
authors.initials: F
authors.lastname: Luo
authors.affiliation: Nephrology Division, Zhengzhou TCM Hospital, Zhengzhou, China.
authors.forename: G S
authors.initials: GS
authors.lastname: Zhang
authors.affiliation: Science and Education Department, Zhengzhou TCM Hospital, Zhengzhou, China.
authors.forename: N
authors.initials: N
authors.lastname: Yang
authors.affiliation: Nephrology Division, Zhengzhou TCM Hospital, Zhengzhou, China.
authors.forename: P
authors.initials: P
authors.lastname: Shen
mesh_terms: D000418:Albumins / Q000378:metabolism; D000740:Anemia / Q000097:blood / Q000188:drug therapy*; D001806:Blood Urea Nitrogen; D002097:C-Reactive Protein / Q000378:metabolism; D002734:Chlorophyll / Q000627:therapeutic use*; D003404:Creatinine / Q000097:blood; D004921:Erythropoietin / Q000378:metabolism; D005260:Female; D005293:Ferritins / Q000097:blood; D006400:Hematocrit; D006454:Hemoglobins / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D013482:Superoxide Dismutase / Q000378:metabolism; D014168:Transferrin / Q000378:metabolism; D016896:Treatment Outcome
chemical_list: D000418:Albumins; D006454:Hemoglobins; D014168:Transferrin; D004921:Erythropoietin; D002734:Chlorophyll; D002097:C-Reactive Protein; D005293:Ferritins; D003404:Creatinine; D013482:Superoxide Dismutase