title: Markovnikov-Selective Addition of Fluorous Solvents to Unactivated Olefins Using a Co Catalyst.
abstract: We developed an addition reaction of fluorous solvents to olefins using salen-cobalt (Co) complex, N-fluoro-2,4,6-trimethylpyridinium tetrafluoroborate, and 1,1,3,3-tetramethyldisiloxane. This reaction condition was found to activate olefins, which enabled them to be attacked by 2,2,2-trifluoroethanol (TFE) and 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP), both of which are electronically weak nucleophiles.
authors.affiliation: Department of Pharmacy, Musashino University.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Shigehisa
authors.forename: Harue
authors.initials: H
authors.lastname: Kikuchi
authors.forename: Kou
authors.initials: K
authors.lastname: Hiroya
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002384:Catalysis; D003035:Cobalt / Q000737:chemistry*; D005461:Fluorine / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D013058:Mass Spectrometry; D012997:Solvents / Q000737:chemistry*; D013055:Spectrophotometry, Infrared
chemical_list: D000475:Alkenes; D012997:Solvents; D005461:Fluorine; D003035:Cobalt