title: Co-existing autosomal dominant polycystic kidney disease and nephrotic syndrome in a Nigerian patient with lupus nephritis.
abstract: A little over 30 cases on co-existing nephrotic syndrome and autosomal dominant polycystic kidney disease (ADPKD) have been reported from different regions of the world since 1957. We present a case report on co-existence of nephrotic syndrome (secondary to lupus nephritis) with ADPKD in a 24-year-old woman from Nigeria. She was positive for anti-double stranded DNA. Renal histology showed International Society of Nephrology/Renal Pathology Society Class II lupus nephritis. The co-existence of nephrotic syndrome and ADPKD may have been overlooked in Africa in the past. There is a need to screen for nephrotic syndrome in patients with ADPKD among clinicians in the African setting.
authors.affiliation: Kidney Care Centre, University of Medical Sciences, Ondo State, Nigeria.
authors.forename: A A
authors.initials: AA
authors.lastname: Akinbodewa
authors.forename: O A
authors.initials: OA
authors.lastname: Adejumo
authors.forename: A O
authors.initials: AO
authors.lastname: Ogunsemoyin
authors.forename: S A
authors.initials: SA
authors.lastname: Osasan
authors.forename: O A
authors.initials: OA
authors.lastname: Adefolalu
mesh_terms: D003956:Dialysis; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage; D007668:Kidney / Q000473:pathology*; D008181:Lupus Nephritis / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D009173:Mycophenolic Acid / Q000008:administration & dosage / Q000031:analogs & derivatives; D009404:Nephrotic Syndrome / Q000150:complications / Q000188:drug therapy / Q000473:pathology*; D009549:Nigeria; D016891:Polycystic Kidney, Autosomal Dominant / Q000150:complications / Q000235:genetics / Q000473:pathology*; D011239:Prednisolone / Q000008:administration & dosage; D011507:Proteinuria / Q000209:etiology; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents; D011239:Prednisolone; D009173:Mycophenolic Acid