title: Chemical Adulterants in Herbal Medicinal Products: A Review.
abstract: Many herbal medicinal products have been found to contain synthetic prescription drugs as chemical adulterants. This has become evident by the number of toxicity cases and adverse reactions reported in which casualties were reported via analytical techniques that detected the presence of chemical adulterants in them, which could be responsible for their toxicity. The adulteration of herbal medicinal products with synthetic drugs continues to be a serious problem for regulatory agencies. This review provides up to date information on cases of toxicity, major chemical adulterants in herbal medicinal products, and current analytical techniques used for their detection.
authors.affiliation: Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, USA.
authors.forename: Jacob
authors.initials: J
authors.lastname: Calahan
authors.affiliation: Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, USA.
authors.forename: Dylan
authors.initials: D
authors.lastname: Howard
authors.affiliation: Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, USA.
authors.forename: Ahmad J
authors.initials: AJ
authors.lastname: Almalki
authors.affiliation: Centro de Investigaciones Farmacognósticas de la Flora Panameña, Facultad de Farmacia, Universidad de Panamá, Panamá, República de Panamá
authors.forename: Mahabir P
authors.initials: MP
authors.lastname: Gupta
authors.affiliation: Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL, USA.
authors.forename: Angela I
authors.initials: AI
authors.lastname: Calderón
mesh_terms: D002855:Chromatography, Thin Layer / Q000379:methods; D004340:Drug Contamination; D019075:Electrophoresis, Capillary / Q000379:methods; D029001:Herbal Medicine; D006801:Humans; D013058:Mass Spectrometry / Q000379:methods; D028321:Plant Preparations / Q000009:adverse effects / Q000737:chemistry* / Q000633:toxicity*; D010946:Plants, Medicinal
chemical_list: D028321:Plant Preparations