title: [Heart transplant: when the candidate is a child].
abstract: Heart transplant (HT) has been considered as a therapy for pediatric end-stage heart failure (HF) for more than four decades. Children with HF represent a very heterogeneous population, affected by different congenital or acquired heart diseases. Progresses in cardiac surgery and medical therapies, leading to improved prognosis, require periodic re-assessment of indications to HT. Systemic diseases, inherited inborn errors of metabolism, genetic syndromes or associated extra-cardiac malformations can contraindicate HT. In these conditions a tailored evaluation is needed. Pediatric heart disease, which more often may be an indication to HT, as well as prognostic parameters in pediatric HF are discussed.
authors.affiliation: S.O.D.C. Cardiologia Pediatrica, Azienda Ospedaliero-Universitaria Meyer, Firenze.
authors.forename: Silvia
authors.initials: S
authors.lastname: Favilli
authors.affiliation: S.O.D.C. Cardiologia Pediatrica, Azienda Ospedaliero-Universitaria Meyer, Firenze.
authors.forename: Gaia
authors.initials: G
authors.lastname: Spaziani
authors.affiliation: S.O.D.C. Cardiologia Pediatrica, Azienda Ospedaliero-Universitaria Meyer, Firenze.
authors.forename: Iva
authors.initials: I
authors.lastname: Pollini
authors.affiliation: S.O.D.C. Cardiologia Pediatrica, Azienda Ospedaliero-Universitaria Meyer, Firenze.
authors.forename: Enrico
authors.initials: E
authors.lastname: Chiappa
mesh_terms: D002648:Child; D006330:Heart Defects, Congenital / Q000150:complications / Q000401:mortality / Q000601:surgery*; D006333:Heart Failure / Q000209:etiology / Q000401:mortality / Q000601:surgery*; D016027:Heart Transplantation / Q000379:methods; D006801:Humans; D010372:Pediatrics; D011379:Prognosis; D018570:Risk Assessment; D012307:Risk Factors; D016896:Treatment Outcome