title: Normal development and experimental embryology: Edmund Beecher Wilson and Amphioxus.
abstract: This paper concerns the concept of normal development, and how it is enacted in experimental procedures. To that end, I use an historical case study to assess the three ways in which normal development is and has been produced, used, and interpreted in the practice of experimental biology. I argue that each of these approaches involves different processes of abstraction, which manage biological variation differently. I then document the way in which Edmund Beecher Wilson, a key contributor to late-nineteenth century experimental embryology, approached the study of normal development and show that his work does not fit any of the three established categories in the taxonomy. On the basis of this new case study, I present a new interpretation of normal development as a methodological norm which operates as a technical condition in various experimental systems. I close by suggesting the questions, and ways of investigating developmental biology, that are opened up by this perspective.
authors.affiliation: Department of Sociology, Philosophy and Anthropology, and Egenis, The Centre for the Study of Life Sciences, University of Exeter, UK. Electronic address: j.w.e.lowe@exeter.ac.uk.
authors.forename: James W E
authors.initials: JW
authors.lastname: Lowe
mesh_terms: D000818:Animals; D015509:Developmental Biology / Q000266:history*; D049672:History, 19th Century; D049673:History, 20th Century; D064175:Lancelets / Q000196:embryology*; D014481:United States
keywords: Abstraction; Edmund Beecher Wilson; Experimental systems; Normal development; Variation