title: In vitroAg Cross-presentation andin vivoAg Cross-presentation by Dendritic Cells in the Mouse.
abstract: Antigen cross presentation is important for effective immune responses to tumors and viral infections. Dendritic cells are professional antigen presenting cells and are unique in their ability to cross-present exogenous antigens on MHC class I molecules and activate antigen specific cytotoxic T cells. This protocol describes antigen cross presentation by dendritic cells (DCs) (bone marrow derived DCs and splenic DCs) in anin vitroand in anin vivoassay system using soluble ovalbumin protein.
authors.forename: Mallika
authors.initials: M
authors.lastname: Ghosh
authors.forename: Linda H
authors.initials: LH
authors.lastname: Shapiro