title: Coinfections: Another Variable in the Herpesvirus Latency-Reactivation Dynamic.
abstract: Chronic viruses, such as herpesviruses, shape host physiology. These viruses modulate the inflammatory state of the immune system and have evolved to harness inflammation as a mechanism to regulate viral latency and reactivation. In this review, I examine some of the recent work demonstrating the important role of inflammation in the regulation of the herpesvirus life cycle and discuss recent work that implicates coinfection in the regulation of herpesvirus latency.
authors.affiliation: Departments of Immunology and Microbiology, University of Texas Southwestern Medical Center, Dallas, Texas, USA tiffany.reese@utsouthwestern.edu.
authors.forename: Tiffany A
authors.initials: TA
authors.lastname: Reese
mesh_terms: D000818:Animals; D060085:Coinfection / Q000276:immunology* / Q000821:virology*; D018142:Gammaherpesvirinae / Q000276:immunology / Q000502:physiology*; D054884:Host-Pathogen Interactions / Q000276:immunology; D006801:Humans; D007249:Inflammation; D051379:Mice; D014775:Virus Activation; D017735:Virus Latency