title: Skin Biomes.
abstract: The cutaneous microbiome has been investigated broadly in recent years and some traditional perspectives are beginning to change. A diverse microbiome exists on human skin and has a potential to influence pathogenic microbes and modulate the course of skin disorders, e.g. atopic dermatitis. In addition to the known dysfunctions in barrier function of the skin and immunologic disturbances, evidence is rising that frequent skin disorders, e.g. atopic dermatitis, might be connected to a dysbiosis of the microbial community and changes in the skin microbiome. As a future perspective, examining the skin microbiome could be seen as a potential new diagnostic and therapeutic target in inflammatory skin disorders.
authors.affiliation: Department of Bacteriology and Immunology, University of Helsinki, Helsinki, Finland.
authors.forename: N
authors.initials: N
authors.lastname: Fyhrquist
authors.affiliation: Department of Dermatology and Allergology, University of Helsinki and Helsinki University, Meilahdentie 2, 00250, Helsinki, Finland.
authors.forename: A
authors.initials: A
authors.lastname: Salava
authors.affiliation: Institute of Biotechnology, DNA Sequencing and Genomics Laboratory, University of Helsinki, Helsinki, Finland.
authors.forename: P
authors.initials: P
authors.lastname: Auvinen
authors.affiliation: Department of Dermatology and Allergology, University of Helsinki and Helsinki University, Meilahdentie 2, 00250, Helsinki, Finland. antti.lauerma@hus.fi.
authors.forename: A
authors.initials: A
authors.lastname: Lauerma
mesh_terms: D000818:Animals; D017753:Ecosystem; D006801:Humans; D054892:Metagenome; D064307:Microbiota; D012867:Skin / Q000382:microbiology*; D012871:Skin Diseases / Q000382:microbiology* / Q000473:pathology
keywords: Cutaneous microbial diversity; Inflammatory skin diseases; Metagenomics; Skin microbiome; Staphylococcus aureus