title: [Optimization of hypolipidemic therapy in patients with ischemic stroke and diabetes mellitus].
abstract: OBJECTIVE
  Evaluation of effectiveness of Mexidol in optimization of hypolipidemic therapy in ischemic stroke and diabetes mellitus patients.
  
  
  METHODS
  Authors analyzed the indicators of lipid status: total cholesterol, low-density lipoproteins, high density lipoproteins, triglycerides and concentration of platelet factor-4, β-tromboglobulin, von Willebrand factor in 68 patients with acute ischemic stroke and diabetes mellitus. Authors investigate the dynamics of these parameters (1(st), 21(st), 3-d and 6(th) month after onset stroke) depending on timing and dose of Mexidol.
  
  
  RESULTS
  Long time therapy of Mexidol may optimize of hypolipidemic therapy in ischemic stroke and diabetes mellitus patients.
authors.affiliation: Research Institute of Experimental and Clinical Medicine, Novosibirsk.
authors.forename: L A
authors.initials: LA
authors.lastname: Shchepankevich
authors.affiliation: Research Institute of Experimental and Clinical Medicine, Novosibirsk.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Nikolaev
authors.affiliation: Research Institute of Experimental and Clinical Medicine, Novosibirsk.
authors.forename: N A
authors.initials: NA
authors.lastname: Dolgova
authors.affiliation: H. Berbekov Kabardino-Balkarian State University, Nalchik, Russia.
authors.forename: D T
authors.initials: DT
authors.lastname: Chipova
mesh_terms: D001792:Blood Platelets / Q000187:drug effects; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D006487:Hemostasis / Q000187:drug effects; D006801:Humans; D000960:Hypolipidemic Agents / Q000494:pharmacology / Q000627:therapeutic use*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D010847:Picolines / Q000627:therapeutic use*; D011446:Prospective Studies; D020521:Stroke / Q000097:blood / Q000150:complications* / Q000188:drug therapy*; D016896:Treatment Outcome; D001620:beta-Thromboglobulin / Q000032:analysis; D014841:von Willebrand Factor / Q000032:analysis
chemical_list: D000960:Hypolipidemic Agents; D008055:Lipids; D010847:Picolines; D001620:beta-Thromboglobulin; D014841:von Willebrand Factor; C070020:emoxypine succinate