title: Relationship of maternal mean platelet volume with fetal Doppler parameters and neonatal complications in pregnancies with and without intrauterine growth restriction.
abstract: OBJECTIVE
  In this study, we investigated the relationship of mean platelet volume (MPV) with the presence and the severity of intrauterine growth restriction (IUGR) and with neonatal complications.
  
  
  METHODS
  The pregnancies with and without IUGR, that were followed-up in our hospital between 2003 and 2009 were analyzed retrospectively. Pregnancies which resulted in birth of a newborn with a birthweight less than 10th percentile for the gestational age were selected for IUGR group. IUGR cases were divided into three groups according to the Doppler parameters.
  
  
  RESULTS
  There was no significant difference between the MPV values in the groups. There was no association between MPV and Doppler parameters that can be used in predicting the severity of IUGR. There was no significant relation between MPV and the perinatal complications such as intracranial hemorrhage (ICH), bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), the development of sepsis, postpartum exitus (PPEX) and intrauterine exitus (IUEX). Higher MPV values were associated with hospitalization in the neonatal intensive care unit (NICU) and respiratory distress syndrome (RDS) in the IUGR group.
  
  
  CONCLUSIONS
  Analysis of MPV is a simple and readily available laboratory test. Prospective researches employing standard measurement technics are required to clarify the relationship between MPV and IUGR.
authors.affiliation: a Department of Gynecology and Obstetrics , Antalya Training and Research Hospital , Antalya , Turkey.
authors.forename: Isin
authors.initials: I
authors.lastname: Ureyen
authors.affiliation: b Department of Gynecology and Obstetrics , Hacettepe University Medical School , Ankara , Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Ozyuncu
authors.affiliation: c Department of Gynecology and Obstetrics , Başkent University Medical School , Ankara , Turkey.
authors.forename: Nihal
authors.initials: N
authors.lastname: Sahin-Uysal
authors.affiliation: d Department of Gynecology and Obstetrics , Zekai Tahir Burak Women's Health Teaching and Research Hospital , Ankara , Turkey , and.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Kara
authors.affiliation: e Department of Gynecology and Obstetrics , Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital , Ankara , Turkey.
authors.forename: Derman
authors.initials: D
authors.lastname: Basaran
authors.affiliation: b Department of Gynecology and Obstetrics , Hacettepe University Medical School , Ankara , Turkey.
authors.forename: Mert
authors.initials: M
authors.lastname: Turgal
authors.affiliation: b Department of Gynecology and Obstetrics , Hacettepe University Medical School , Ankara , Turkey.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Deren
mesh_terms: D000293:Adolescent; D000328:Adult; D001724:Birth Weight; D016022:Case-Control Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000097:blood* / Q000000981:diagnostic imaging; D005500:Follow-Up Studies; D006801:Humans; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000097:blood* / Q000175:diagnosis / Q000209:etiology; D007236:Infant, Small for Gestational Age; D063847:Mean Platelet Volume; D011247:Pregnancy; D012016:Reference Values; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D018608:Ultrasonography, Doppler / Q000379:methods*; D016216:Ultrasonography, Prenatal; D014469:Umbilical Arteries / Q000000981:diagnostic imaging; D055815:Young Adult
keywords: Intrauterine growth restriction; mean platelet volume; perinatal complications