title: Case report of an anal adenocarcinoma arising from a perineal lump.
abstract: Anal adenocarcinoma is a rare condition and can arise in chronic inflammatory states such as in Crohn's disease, or in a chronic fistula-in-ano. We report our diagnosis and management of a patient who presented with a large perineal lump with a long-standing history of perianal fistulous disease. This was initially evaluated with a Magnetic Resonance Imaging, and the diagnosis was confirmed with biopsy. Multimodality treatment with chemoradiotherapy and surgery should be offered to achieve the best outcomes.
authors.affiliation: Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore.
authors.forename: Dedrick Kok-Hong
authors.initials: DK
authors.lastname: Chan
authors.affiliation: Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore.
authors.forename: Choon-Seng
authors.initials: CS
authors.lastname: Chong
authors.affiliation: Division of Colorectal Surgery, University Surgical Cluster, National University Health System, Singapore; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Ker-Kan
authors.initials: KK
authors.lastname: Tan
keywords: Anal adenocarcinoma; Chronic inflammation; Perineal lump