title: Summertime Dyskinesia-Hyperpyrexia Syndrome: The "Dual Heat" Hypothesis.
abstract: The dyskinesia-hyperpyrexia syndrome is a rare complication of Parkinson disease. Here, we present an exceptional case affected by this syndrome. Its singularity is 2-fold. On one hand, the patient presented periodic episodes of dyskinesia-hyperpyrexia during 3 consecutive summers. On the other, after unsuccessfully trying several therapies, she had an excellent response to an infusion of enteral L-dopa. Both features allow us to hypothesize that this complication is central in origin and propose a new potential mean of treating future refractory cases.
authors.affiliation: *Department of Neurology, "Infanta Leonor" Hospital; and †Department of Neurology, "Doce de Octubre" Hospital, Madrid, Spain; ‡Research Laboratory of Electronics, Massachusetts Institute of Technology (MIT), Cambridge, MA; and §Centro Integral en Neurociencias HM CINAC, HM Hospitales, Madrid, Spain.
authors.forename: Jaime
authors.initials: J
authors.lastname: Herreros-Rodriguez
authors.forename: Álvaro
authors.initials: Á
authors.lastname: Sánchez-Ferro
mesh_terms: D000368:Aged; D004409:Dyskinesia, Drug-Induced / Q000209:etiology*; D005260:Female; D006358:Hot Temperature / Q000009:adverse effects*; D006801:Humans; D007958:Leukocyte Count; D007980:Levodopa / Q000009:adverse effects; D010300:Parkinson Disease / Q000178:diet therapy
chemical_list: D007980:Levodopa