title: Surgical treatment for pelvic giant cell tumor: a multi-center study.
abstract: BACKGROUND
  The purpose of this study was to discuss the clinical results which related to the location of giant cell tumors (GCTs) in the pelvis so as to determine the ideal surgical treatment protocol.
  
  
  METHODS
  We report 29 cases who accepted surgical treatment from five clinical centers during the last 12 years. All patients were divided into three groups according to tumor locations, and they were also classified into two groups in light of surgical treatments. The parameters for outcome evaluation consisting of general condition, surgical complications, local disease control, and Musculoskeletal Tumor Society (MSTS) 93 functional score had been analyzed, respectively.
  
  
  RESULTS
  Surgical treatment in the acetabular area usually resulted in postoperative complications and poor function. One patient who accepted intralesional surgery and two who accepted wide resection had local recurrence. The mean functional score was 25.4 for the 8 patients who received intralesional surgery and 21.9 for the 21 patients who received wide resection. Surgical complications occurred in 1 patient who underwent intralesional surgery and the other 6 patients who underwent wide resection.
  
  
  CONCLUSIONS
  We conclude that surgical treatment of pelvic GCTs in the acetabular area is difficult to select as it is always accompanied by complications and poor function. Compared to wide resection, intralesional surgery combined with a meticulous preoperative planning may lower the recurrence rate and obtain favorable postoperative functional results.
authors.affiliation: Second Military Medical University, Shanghai, China.|Department of Orthopaedics, The General Hospital of Jinan Military Commanding Region, Jinan, Shandong, China.|Giant Cell Tumor Group of China (GTOC), Beijing, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Zheng
authors.affiliation: Second Military Medical University, Shanghai, China. yxch48@vip.sina.com.|Department of Orthopaedics, The General Hospital of Jinan Military Commanding Region, Jinan, Shandong, China. yxch48@vip.sina.com.|Giant Cell Tumor Group of China (GTOC), Beijing, China. yxch48@vip.sina.com.
authors.forename: Xiuchun
authors.initials: X
authors.lastname: Yu
authors.affiliation: Department of Bone Oncology, Tianjin Hospital, Tianjin, China. yongchenghu@126.com.|Giant Cell Tumor Group of China (GTOC), Beijing, China. yongchenghu@126.com.
authors.forename: Yongcheng
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xian, Shannxi, China.|Giant Cell Tumor Group of China (GTOC), Beijing, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Orthopaedics, Jinling Hospital, Clinical School of Medical College, Nanjing University, Nanjing, Jiangsu, China.|Giant Cell Tumor Group of China (GTOC), Beijing, China.
authors.forename: Sujia
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Orthopaedics, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang, China.|Giant Cell Tumor Group of China (GTOC), Beijing, China.
authors.forename: Zhaoming
authors.initials: Z
authors.lastname: Ye
mesh_terms: D000293:Adolescent; D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D018212:Giant Cell Tumor of Bone / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D010384:Pelvic Bones / Q000473:pathology / Q000601:surgery*; D011379:Prognosis; D012189:Retrospective Studies; D055815:Young Adult
keywords: Giant cell tumor; Pelvis; Surgical treatment