title: Cardiac time intervals derived by magnetocardiography in fetuses exposed to pregnancy hypertension syndromes.
abstract: To test the hypothesis that fetuses exposed to maternal preeclampsia or chronic hypertension have deranged development of cardiac time intervals.
  
  
  
  Pregnancies were divided into three groups: Intrauterine Growth Restricted (IUGR), Hypertensive, and Normal. Each group's mean fetal cardiac time intervals (P, PR, QRS and RR) derived by magnetocardiography were calculated using an analysis of covariance model's regression-adjusted estimates for a gestational age of 35 weeks.
  
  
  
  We reviewed 141 recordings from 21 IUGR, 46 Hypertensive and 74 Normal patients. The IUGR, Hypertensive and Normal groups, respectively, had adjusted mean intervals in milliseconds of 66.4, 66.8 and 76.2 for P (P=0.001), 95.9, 101.6 and 109.6 for PR (P=0.002), 77.2, 78.7 and 78.7 for QRS (P=0.81) and 429.8, 429.2 and 428.5 for RR (P=0.97).
  
  
  
  P and PR intervals are abbreviated in normotrophic fetuses exposed to maternal hypertension, suggesting shortened atrioventricular conduction times.
authors.affiliation: Department of Pediatrics, Division of Cardiology, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR, USA.
authors.forename: E H
authors.initials: EH
authors.lastname: Bolin
authors.affiliation: Department of Biostatistics, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
authors.forename: E R
authors.initials: ER
authors.lastname: Siegel
authors.affiliation: Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
authors.forename: H
authors.initials: H
authors.lastname: Eswaran
authors.affiliation: Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, AR, USA.
authors.forename: C L
authors.initials: CL
authors.lastname: Lowery
authors.affiliation: Department of Pediatrics, Division of Cardiology, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR, USA.
authors.forename: D
authors.initials: D
authors.lastname: Zakaria
authors.affiliation: Department of Pediatrics, Division of Cardiology, University of Arkansas for Medical Sciences, Arkansas Children's Hospital, Little Rock, AR, USA.
authors.forename: T H
authors.initials: TH
authors.lastname: Best
mesh_terms: D000328:Adult; D001131:Arkansas; D016022:Case-Control Studies; D005260:Female; D005317:Fetal Growth Retardation / Q000503:physiopathology*; D005318:Fetal Heart / Q000503:physiopathology*; D005865:Gestational Age; D006340:Heart Rate, Fetal; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000503:physiopathology*; D053798:Magnetocardiography; D011225:Pre-Eclampsia / Q000503:physiopathology*; D011247:Pregnancy; D012044:Regression Analysis; D055815:Young Adult