title: 68Ga-PSMA PET/CT Imaging and 153Sm-EDTMP Bone Pain Palliation Therapy.
abstract: Ga-labeled prostate-specific membrane antigen (PSMA) is a potential tool in the imaging of recurrent prostate cancer. Ga-PSMA imaging is also useful for radiotherapy planning and in targeted therapy with Lu-PSMA. A few case reports regarding the use of Ga-PSMA in nonprostate cancer malignancies are also reported. We describe the use of Ga-PSMA imaging before Sm-EDTMP bone pain palliation therapy in a 58-year-old hormone refractory prostate cancer patient with extensive bone metastases.
authors.affiliation: From the *Department of Nuclear Medicine and PET/CT, KIMS-DDNMRC; and †Department of Medical Oncology, KIMS Cancer Centre, KIMS Hospital, Trivandrum, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Sasikumar
authors.forename: Ajith
authors.initials: A
authors.lastname: Joy
authors.forename: Raviteja
authors.initials: R
authors.lastname: Nanabala
authors.forename: M R A
authors.initials: MR
authors.lastname: Pillai
authors.forename: Boben
authors.initials: B
authors.lastname: Thomas
mesh_terms: D018712:Analgesics, Non-Narcotic / Q000627:therapeutic use*; D000954:Antigens, Surface; D001859:Bone Neoplasms / Q000000981:diagnostic imaging* / Q000556:secondary; D005710:Gallium Radioisotopes / Q000493:pharmacokinetics; D043425:Glutamate Carboxypeptidase II / Q000493:pharmacokinetics; D006801:Humans; D008297:Male; D008875:Middle Aged; D009942:Organometallic Compounds / Q000627:therapeutic use*; D009943:Organophosphorus Compounds / Q000627:therapeutic use*; D010146:Pain / Q000188:drug therapy*; D010166:Palliative Care / Q000379:methods; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*
chemical_list: D018712:Analgesics, Non-Narcotic; D000954:Antigens, Surface; D005710:Gallium Radioisotopes; D009942:Organometallic Compounds; D009943:Organophosphorus Compounds; C061972:samarium Sm-153 lexidronam; C473848:FOLH1 protein, human; D043425:Glutamate Carboxypeptidase II