title: Effect of muscarinic blocker on enhancing the action of fructus aurantii immaturus on intestinal myoelectric activity in dogs.
abstract: OBJECTIVE
  To investigate the effect of fructus aurantii immaturus (FAI) on small intestinal electrical activity in dogs.
  
  
  METHODS
  The effect of FAI was observed using a computerized electrophysiological method with the migrating myoelectric complex as a criterion. Fasted, healthy, and conscious dogs were given 100% FAI concentrated solution by gastrostogavage, and as soon as the effect on small intestinal electrical activity appeared, atropine was injected intramuscularly.
  
  
  RESULTS
  The enhancing action of FAI was inhibited significantly by atropine, a cholinergic receptor antagonist. Both the number of spike bursts per cluster and the number of spikes per minute in phase II and III and the general cycle were decreased (P < 0.01), although the duration of phase II and the general cycle was prolonged.
  
  
  CONCLUSIONS
  The effect of FAI might be related to the muscarinic receptors.
authors.affiliation: Zi-He Huang, Yin-Hui Luo, Second Affiliated Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China.
authors.forename: Z H
authors.initials: ZH
authors.lastname: Huang
authors.affiliation: Zi-He Huang, Yin-Hui Luo, Second Affiliated Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China.
authors.forename: D Z
authors.initials: DZ
authors.lastname: Yang
authors.affiliation: Zi-He Huang, Yin-Hui Luo, Second Affiliated Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China.
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Wei
authors.affiliation: Zi-He Huang, Yin-Hui Luo, Second Affiliated Hospital of Shantou University Medical College, Shantou 515031, Guangdong Province, China.
authors.forename: Y H
authors.initials: YH
authors.lastname: Luo
keywords: Atropine; Electrophysiology; Fructus aurantii immaturus; Small intestine