title: Syphilis: presentations in general medicine.
abstract: Syphilis is caused by the spirochete bacteriumTreponema pallidumand can be transmitted both sexually and from mother to child.T pallidumcan infect any organ and produces a clinical disease with a relapsing and remitting course. It is not hard to see, therefore, why it is often described as the great mimic. In this review, we provide an update of modern syphilis epidemiology, clinical presentations, and testing and treatment strategies.
authors.affiliation: Jefferiss Wing for Sexual Health, Imperial College NHS Healthcare Trust, London, UK.
authors.forename: Farai
authors.initials: F
authors.lastname: Nyatsanza
authors.affiliation: Jefferiss Wing for Sexual Health, Imperial College NHS Healthcare Trust, London, UK craig.tipple@imperial.nhs.uk.
authors.forename: Craig
authors.initials: C
authors.lastname: Tipple
mesh_terms: D019468:Disease Management; D006801:Humans; D013587:Syphilis / Q000175:diagnosis / Q000453:epidemiology / Q000473:pathology / Q000628:therapy
keywords: Syphilis; Treponema pallidum; epidemiology; neurosyphilis; treatment