title: Comorbidity in rheumatoid arthritis.
abstract: Rheumatoid arthritis (RA) is a chronic inflammatory condition, which is associated with an increased risk of comorbidity from other diseases. RA disease severity is a major predictor of development of cardiovascular disease, serious infections and malignant lymphoma. This reflects the role of chronic inflammation in the underlying pathology. Recent surveys indicate that although clinical outcomes have improved in patients with RA, mainly owing to access to more efficient pharmacotherapy, comorbidity remains a major issue in many patients. Register-based observational studies are useful sources of information on the impact of comorbidity and the efficacy and safety of antirheumatic treatment in patients with coexisting diseases. As a part of strategies to improve further the management of patients with RA, multidisciplinary collaboration for prevention and early detection of comorbidities is of major importance.
authors.affiliation: Rheumatology, Department of Clinical Sciences, Malmö, Faculty of Medicine, Lund University, Sweden; and Department of Rheumatology, Skåne University Hospital, Malmö, Sweden.
authors.forename: Carl
authors.initials: C
authors.lastname: Turesson
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000188:drug therapy / Q000453:epidemiology*; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015897:Comorbidity; D006801:Humans; D007239:Infections / Q000453:epidemiology*; D008223:Lymphoma / Q000453:epidemiology*; D009369:Neoplasms / Q000453:epidemiology
chemical_list: D018501:Antirheumatic Agents