title: Angiosarcoma Causing Cardiac Constriction Late after Radiation Therapy for Breast Carcinoma.
abstract: Therapeutic radiotherapy rarely causes sarcoma, and this occurs years after completion of the intended treatment. In treating breast carcinoma, careful planning in the application of modern radiotherapeutic techniques usually can shield the heart and pericardium. We report a rare case of angiosarcoma of the pericardium, which presented in a 41-year-old woman as constrictive pericarditis 8 years after irradiation for cancer of the left breast. To our knowledge, this is only the 2nd report of angiosarcoma of the pericardium after radiotherapy.
authors.forename: Ashwini
authors.initials: A
authors.lastname: Sharma
authors.forename: Patrick A
authors.initials: PA
authors.lastname: DeValeria
authors.forename: Robyn M
authors.initials: RM
authors.lastname: Scherber
authors.forename: Gavin
authors.initials: G
authors.lastname: Sugrue
authors.forename: Ann E
authors.initials: AE
authors.lastname: McCullough
authors.forename: Prasad M
authors.initials: PM
authors.lastname: Panse
authors.forename: Farouk
authors.initials: F
authors.lastname: Mookadam
mesh_terms: D000328:Adult; D001706:Biopsy; D001943:Breast Neoplasms / Q000175:diagnosis / Q000532:radiotherapy*; D002291:Carcinoma, Papillary / Q000175:diagnosis / Q000532:radiotherapy*; D005260:Female; D006394:Hemangiosarcoma / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D010494:Pericarditis, Constrictive / Q000175:diagnosis / Q000209:etiology*; D010997:Pleural Neoplasms / Q000150:complications* / Q000175:diagnosis; D011832:Radiation Injuries / Q000150:complications* / Q000175:diagnosis; D014057:Tomography, X-Ray Computed
keywords: Angiosarcoma; constrictive pericarditis; neoplasms, radiation-induced; pericardium/radiation effects; postradiation tumor; radiotherapy/adverse effects