title: Peripherally inserted central catheters optimize nutrient intake in moderately preterm infants.
abstract: While very preterm (<32 wk gestation) infants are routinely provided intensive nutritional support via central line, clinical practice varies for nutrient delivery in infants born moderately preterm (32-34 wk gestation). We sought to define the impact of nutritional support via peripherally inserted central catheter (PICC) on nutrient delivery in the first 2 wk of life and growth by discharge.
  
  
  
  Data were extracted from the records of 187 infants born between 32 and 34 6/7 wk gestation and admitted to the University of Iowa Children's Hospital between April 2012 and December 2013. Records of all feedings, weights, and PICC placements were collected. The growth outcomes at discharge for infants who received nutrition via PICC were compared to those who did not.
  
  
  
  In the first week of life, newborns who received nutrition via PICC line received 17.6 more kilocalories (confidence interval (CI): 12.5-22.7, P < 0.001) and 1.2 more grams protein per kilogram body weight per day (CI: 0.9-1.4, P < 0.001) compared to control infants. By discharge, the PICC group had gained 302 g more body weight (P < 0.001).
  
  
  
  This study demonstrates superior nutrient intake and growth in the first 2 wk of life for infants who received nutrition via PICC line.
authors.affiliation: Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa.
authors.forename: Anne L
authors.initials: AL
authors.lastname: Smazal
authors.affiliation: Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa.
authors.forename: Anne B
authors.initials: AB
authors.lastname: Kavars
authors.affiliation: Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa.
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Carlson
authors.affiliation: Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa.
authors.forename: Tarah T
authors.initials: TT
authors.lastname: Colaizy
authors.affiliation: Department of Pediatrics, University of Iowa Children's Hospital, Iowa City, Iowa.
authors.forename: John M
authors.initials: JM
authors.lastname: Dagle
mesh_terms: D002405:Catheterization, Central Venous / Q000009:adverse effects / Q000379:methods*; D002406:Catheterization, Peripheral / Q000379:methods*; D002149:Energy Intake; D004750:Enteral Nutrition; D005260:Female; D005865:Gestational Age; D006801:Humans; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007234:Infant, Premature; D007363:Intensive Care Units, Neonatal; D008297:Male; D010289:Parenteral Nutrition, Total