title: Acute lead poisoning in western Canadian cattle - A 16-year retrospective study of diagnostic case records.
abstract: This study describes the epidemiology of acute lead poisoning in western Canadian cattle over the 16-year period of 1998 to 2013 and reports background bovine tissue lead concentrations. Case records from Prairie Diagnostic Services, Western College of Veterinary Medicine, identified 525 cases of acute lead toxicity over the investigational period. Poisonings were influenced by year (P < 0.0001) and month (P < 0.0001). Submissions were highest in 2009 (15.6%), 2001 (11.2%), and 2006 (9.9%). Most cases were observed during May, June, and July (62.3%). Cattle 6 months of age and younger were frequently poisoned (53.5%; P < 0.0001). Beef breeds were predominantly poisoned. Mean toxic lead concentrations (mg/kg wet weight) in the blood, liver, and kidney were 1.30 ± 1.70 (n = 301), 33.5 ± 80.5 (n = 172), and 56.3 ± 39.7 (n = 61). Mean normal lead concentrations in the blood, liver, and kidney were 0.036 ± 0.003 mg/kg (n= 1081), 0.16 ± 0.63 mg/kg (n = 382), and 0.41 ± 0.62 mg/kg (n = 64).
authors.affiliation: Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine and Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4.
authors.forename: Vanessa
authors.initials: V
authors.lastname: Cowan
authors.affiliation: Department of Veterinary Biomedical Sciences, Western College of Veterinary Medicine and Toxicology Centre, University of Saskatchewan, Saskatoon, Saskatchewan S7N 5B4.
authors.forename: Barry
authors.initials: B
authors.lastname: Blakley
mesh_terms: D000818:Animals; D002170:Canada / Q000453:epidemiology; D002417:Cattle; D002418:Cattle Diseases / Q000453:epidemiology*; D007668:Kidney / Q000737:chemistry; D007854:Lead / Q000097:blood; D007855:Lead Poisoning / Q000453:epidemiology / Q000662:veterinary*; D008099:Liver / Q000737:chemistry; D000069466:Red Meat / Q000032:analysis; D012189:Retrospective Studies
chemical_list: D007854:Lead