title: Synthesis of 2-aryl-2H-tetrazoles via a regioselective [3+2] cycloaddition reaction.
abstract: A regioselective cycloaddition reaction of arenediazonium salts with trimethylsilyldiazomethane is reported. A series of 2-aryltetrazoles were obtained in good to moderate yields with wide functional group compatibility. Furthermore, this cycloaddition reaction opens the way to build up the versatile intermediate 2-aryl-5-bromotetrazole.
authors.affiliation: The Scripps Research Institute, Scripps Florida, Department of Molecular Therapeutics, 130 Scripps Way #A2A, Jupiter, FL 33458, USA.
authors.forename: Remi
authors.initials: R
authors.lastname: Patouret
authors.affiliation: The Scripps Research Institute, Scripps Florida, Department of Molecular Therapeutics, 130 Scripps Way #A2A, Jupiter, FL 33458, USA.
authors.forename: Theodore M
authors.initials: TM
authors.lastname: Kamenecka
keywords: 2H-Tetrazole; Silver catalysis; Trimethylsilyldiazomethane; [3+2] Cycloaddition