title: Active learning based segmentation of Crohns disease from abdominal MRI.
abstract: This paper proposes a novel active learning (AL) framework, and combines it with semi supervised learning (SSL) for segmenting Crohns disease (CD) tissues from abdominal magnetic resonance (MR) images. Robust fully supervised learning (FSL) based classifiers require lots of labeled data of different disease severities. Obtaining such data is time consuming and requires considerable expertise. SSL methods use a few labeled samples, and leverage the information from many unlabeled samples to train an accurate classifier. AL queries labels of most informative samples and maximizes gain from the labeling effort. Our primary contribution is in designing a query strategy that combines novel context information with classification uncertainty and feature similarity. Combining SSL and AL gives a robust segmentation method that: (1) optimally uses few labeled samples and many unlabeled samples; and (2) requires lower training time. Experimental results show our method achieves higher segmentation accuracy than FSL methods with fewer samples and reduced training effort.
authors.affiliation: Department of Computer Science, ETH Zurich, Switzerland. Electronic address: dwarikanath.mahapatra@inf.ethz.ch.
authors.forename: Dwarikanath
authors.initials: D
authors.lastname: Mahapatra
authors.affiliation: Department of Radiology, Academic Medical Center, The Netherlands; Quantitative Imaging Group, Delft University of Technology, The Netherlands.
authors.forename: Franciscus M
authors.initials: FM
authors.lastname: Vos
authors.affiliation: Department of Computer Science, ETH Zurich, Switzerland.
authors.forename: Joachim M
authors.initials: JM
authors.lastname: Buhmann
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging*; D000465:Algorithms; D003424:Crohn Disease / Q000000981:diagnostic imaging*; D003936:Diagnosis, Computer-Assisted / Q000379:methods*; D019277:Entropy; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D000069550:Machine Learning; D008279:Magnetic Resonance Imaging; D015233:Models, Statistical; D018794:Problem-Based Learning / Q000379:methods*; D015203:Reproducibility of Results; D012984:Software
keywords: Active learning; Crohns disease; Graph cuts; Label query; Segmentation; Semi supervised classification