title: Ultrasound-guided percutaneous ethanol ablation for primary non-parasitic splenic cysts in 15 patients.
abstract: OBJECTIVE
  This study aimed to evaluate the feasibility, safety, and efficacy of ultrasound (US)-guided percutaneous ethanol ablation (PEA) for primary non-parasitic splenic cysts.
  
  
  METHODS
  Between February 2006 and February 2015, 15 patients (4 men and 11 women; mean age, 33 ± 15.3 years; age range, 17-65 years) with primary non-parasitic splenic cysts were treated with US-guided PEA. 99.5% absolute ethanol in an amount of approximately 50%-100% of the aspirated volume was injected into each cyst and no more than 240 mL. Standard laboratory tests (hemogram, coagulation, serum, and biochemical tumor marker levels) were performed before and after PEA.
  
  
  RESULTS
  The median follow-up time was 18.7 months (range 2.8-59.2 months). During follow-up, seven cysts after treatment had disappeared completely, while the other eight cysts had decreased significantly in size. The 3-, 6-, 12-, and 24-month volume reduction rates were 49.7%, 87.6%, 94.3%, and 96.7%. Serum tumor marker CA19-9 levels significantly decreased. Mild adverse reactions included moderate pain in four (26.7%), unbearable pain in one (6.67%), fever in two (13.3%) and slight intracystic bleeding in one (6.67%). There were no serious complications.
  
  
  CONCLUSIONS
  US-guided PEA appears to be a safe and effective minimally invasive technique for management of primary non-parasitic splenic cysts.
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
authors.forename: Xiaohuan
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Yu
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China. liangping301@hotmail.com.
authors.forename: Ping
authors.initials: P
authors.lastname: Liang
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
authors.forename: Xiaoling
authors.initials: X
authors.lastname: Yu
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Cheng
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
authors.forename: Zhiyu
authors.initials: Z
authors.lastname: Han
authors.affiliation: Department of Interventional Ultrasound, Chinese PLA General Hospital, 28 Fuxing Road, Beijing, 100853, China.
authors.forename: Fangyi
authors.initials: F
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003560:Cysts / Q000628:therapy*; D000431:Ethanol / Q000627:therapeutic use*; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D012597:Sclerosing Solutions / Q000627:therapeutic use*; D015911:Sclerotherapy / Q000379:methods*; D013158:Splenic Diseases / Q000628:therapy*; D016896:Treatment Outcome; D018084:Ultrasonography, Interventional; D055815:Young Adult
chemical_list: D012597:Sclerosing Solutions; D000431:Ethanol
keywords: Percutaneous ethanol ablation; Sclerotherapy; Splenic cysts; Ultrasound