title: Clinical outcomes of implant therapy in ectodermal dysplasia patients: a systematic review.
abstract: The purpose of this review was to determine the outcome of oral function reconstruction in ectodermal dysplasia (ED) patients who have received dental implant therapy. A search was made of the PubMed and Web of Science databases; key words used were "(ectodermal dysplasia) AND (implant OR implants)", with supplementary retrieval key words "dental implant", "zygomatic implant", "anodontia", and "edentulous". Patient age, use of bone graft, implant site, type of implant, and survival rate of the implants were included in the subsequent data analysis. Forty-five articles published between 1988 and October 2015 were included in this analysis. The cases of a total of 96 patients were retrieved (22 children and 74 adults); these patients received a total of 701 implants. Fourteen implants were removed during a median follow-up time of 24 months. The 24-month implant survival rate was 97.9% in adult subjects and 98.6% in children. Sixty-eight percent of adult patients underwent bone augmentation prior to implant placement. Based on this review, dental implants are commonly used in the oral reconstruction of ED patients. However, long-term data on bone augmentation and implant success are needed, as well as additional clinical evidence on bone resorption, the esthetic outcomes of implant therapy, and physiological considerations in ED patients.
authors.affiliation: Dental Implant Centre, Stomatology Hospital and College, Key Laboratory of Oral Diseases Research of Anhui Province, Anhui Medical University, Hefei, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Dental Implant Centre, Stomatology Hospital and College, Key Laboratory of Oral Diseases Research of Anhui Province, Anhui Medical University, Hefei, China.
authors.forename: J
authors.initials: J
authors.lastname: He
authors.affiliation: Department of Periodontics and Oral Medicine, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
authors.forename: A M
authors.initials: AM
authors.lastname: Decker
authors.affiliation: Department of Biologic and Materials Sciences, University of Michigan School of Dentistry, Ann Arbor, MI, USA.
authors.forename: J C
authors.initials: JC
authors.lastname: Hu
authors.affiliation: Dental Implant Centre, Stomatology Hospital and College, Key Laboratory of Oral Diseases Research of Anhui Province, Anhui Medical University, Hefei, China. Electronic address: zdhyy@ahmu.edu.cn.
authors.forename: D
authors.initials: D
authors.lastname: Zou
mesh_terms: D000328:Adult; D002648:Child; D003758:Dental Implantation, Endosseous; D015921:Dental Implants / Q000706:statistics & numerical data*; D019094:Dental Prosthesis, Implant-Supported; D019232:Dental Restoration Failure / Q000706:statistics & numerical data; D004476:Ectodermal Dysplasia / Q000601:surgery*; D004955:Esthetics, Dental; D006801:Humans; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants
keywords: dental implant; ectodermal dysplasia; oral function reconstruction