title: Chemo- and regioselective reductive deoxygenation of 1-en-4-yn-ols into 1,4-enynes through FeF3 and TfOH co-catalysis.
abstract: We report chemo- and regioselective direct reductive deoxygenation of 1-en-4-yn-3-ols into 1,4-enynes through FeF3 and TfOH cooperative catalysis under NBSH-mediated conditions. Further, we show the efficient synthesis of a pharmaceutically significant 1,4-enyne. The present methodology can also be used for chemo- and regioselective direct deoxygenation of other alcohols.
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China. bixh507@nenu.edu.cn.
authors.forename: Zonglian
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China. bixh507@nenu.edu.cn.
authors.forename: Rapolu Kiran
authors.initials: RK
authors.lastname: Kumar
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China. bixh507@nenu.edu.cn.
authors.forename: Peiqiu
authors.initials: P
authors.lastname: Liao
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China. bixh507@nenu.edu.cn.
authors.forename: Zhaohong
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China. bixh507@nenu.edu.cn.
authors.forename: Xingqi
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China. bixh507@nenu.edu.cn and State Key Laboratory of Elemento-Organic Chemistry, Nankai University, 300071 Tianjin, China.
authors.forename: Xihe
authors.initials: X
authors.lastname: Bi