title: A Rare and Extensive Case of Oral Malignant Melanoma involving Mandibular Gingiva.
abstract: Oral malignant melanoma is an infrequent but an aggressive neoplasm of unknown etiology, seen most commonly in middle age male patients and is more frequently seen at the hard palate and gingiva. The tumor tends to metastasize or locally invade tissue more readily than other malignant tumors in the oral region. In this article, we report a rare case of extensive oral melanoma in a 55-year-old male patient, with a chief complaint of painless growth in mandibular anterior gingiva measuring about 2.6 X 1.7 X 0.8 cm and extending bilaterally till posterior mandibular gingiva and unilaterally to right buccal mucosa. The most common site being hard palate and maxillary gingiva, it is extremely rare in mandibular gingiva (less than 7%) and hence, this rare occurrence in mandibular gingiva is reported, the diagnosis of which was confirmed by histopathology and immunohistochemistry.
authors.affiliation: Professor and Head of Department, Department of Oral Pathology, Manubhai Patel Dental College & Hospital , Vadodara, Gujarat, India .
authors.forename: Rajendrasinh S
authors.initials: RS
authors.lastname: Rathore
authors.affiliation: Professor, Department of Oral Pathology, Manubhai Patel Dental College & Hospital , Vadodara, Gujarat, India .
authors.forename: Rashmi Gs
authors.initials: RG
authors.lastname: Phulari
authors.affiliation: Senior Lecturer, Department of Oral Pathology, Manubhai Patel Dental College & Hospital , Vadodara, Gujarat, India .
authors.forename: Dharmesh G
authors.initials: DG
authors.lastname: Vasavada
authors.affiliation: Senior Lecturer, Department of Oral Pathology, Manubhai Patel Dental College & Hospital , Vadodara, Gujarat, India .
authors.forename: Dipen K
authors.initials: DK
authors.lastname: Patel
keywords: HMB-45; Melanocytes; Nodular malignant melanoma