title: A new and highly selective turn-on fluorescent sensor with fast response time for the monitoring of cadmium ions in cosmetic, and health product samples.
abstract: Cadmium (Cd) which is an extremely toxic could be found in many products like plastics, fossil fuel combustion, cosmetics, water resources, and wastewaters. It is capable of causing serious environmental and health problems such as lung, prostate, renal cancers and the other disorders. So, the development of a sensor to continually monitor cadmium is considerably demanding. Tetrakis(4-nitrophenyl)porphyrin, T(4-NO2-P)P, was synthesized and used as a new and highly selective fluorescent probe for monitoring cadmium ions in the "turn-on" mode. There was a linear relationship between fluorescence intensity and the concentration of Cd(II) in the range of 1.0×10(-6) to 1.0×10(-5)molL(-1) with a detection limit of 0.276μM. To examine the most important parameters involved and their interactions in the sensor optimization procedure, a four-factor central composite design (CCD) combined with response surface modeling (RSM) was implemented. The practical applicability of the developed sensor was investigated using real cosmetic, and personal care samples.
authors.affiliation: Department of Chemistry, Faculty of Science, University of Birjand, P.O. Box 414, Birjand, Iran.
authors.forename: Rouhollah
authors.initials: R
authors.lastname: Khani
authors.affiliation: Department of Chemistry, Faculty of Science, University of Birjand, P.O. Box 414, Birjand, Iran. Electronic address: eghiamati@birjand.ac.ir.
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Ghiamati
authors.affiliation: Department of Chemistry, Faculty of Science, University of Birjand, P.O. Box 414, Birjand, Iran.
authors.forename: Ramin
authors.initials: R
authors.lastname: Boroujerdi
authors.affiliation: Department of Chemistry, Faculty of Science, University of Birjand, P.O. Box 414, Birjand, Iran.
authors.forename: Abdolreza
authors.initials: A
authors.lastname: Rezaeifard
authors.affiliation: Department of Chemistry, Faculty of Science, University of Birjand, P.O. Box 414, Birjand, Iran.
authors.forename: Mohadeseh Hosseinpour
authors.initials: MH
authors.lastname: Zaryabi
mesh_terms: D000704:Analysis of Variance; D002104:Cadmium / Q000032:analysis*; D003358:Cosmetics / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D007477:Ions; D008968:Molecular Conformation; D013050:Spectrometry, Fluorescence / Q000295:instrumentation* / Q000379:methods*; D013056:Spectrophotometry, Ultraviolet; D013997:Time Factors
chemical_list: D003358:Cosmetics; D005456:Fluorescent Dyes; D007477:Ions; D002104:Cadmium
keywords: Cadmium; Cosmetic samples; Fluorescent probe; Multivariate optimization; Porphyrin; Turn-on sensor