title: Acetazolamide polymorphism: a case of hybridization induced polymorphism?
abstract: The unusual phenomenon of the formation of the kinetic form as against the thermodynamic form upon slow cooling of boiling aqueous solution in the case of diuretic drug acetazolamide is rationalized in terms of "hybridization induced polymorphism" based on extensive experimental and theoretical investigations.
authors.affiliation: Solid State and Structural Chemistry Unit, Indian Institute of Science, Bangalore 560 012, India. ssctng@sscu.iisc.ernet.in.
authors.forename: Sounak
authors.initials: S
authors.lastname: Sarkar
authors.forename: Mysore S
authors.initials: MS
authors.lastname: Pavan
authors.forename: Suryanarayan
authors.initials: S
authors.lastname: Cherukuvada
authors.forename: Tayur N
authors.initials: TN
authors.lastname: Guru Row
mesh_terms: D000086:Acetazolamide / Q000737:chemistry*; D003460:Crystallization; D004232:Diuretics / Q000737:chemistry*; D008956:Models, Chemical; D008968:Molecular Conformation; D015394:Molecular Structure; D014961:X-Ray Diffraction
chemical_list: D004232:Diuretics; D000086:Acetazolamide