title: A Nutritional Approach to the Prevention of Cancer: from Assessment to Personalized Intervention.
abstract: Among lifestyle factors, nutrition is one of the most important determinants of health, and represents a pivotal element of cancer risk. Nonetheless, epidemiological evidences of the relationship between several cancers and specific foods and nutrients is still inadequate, and solid conclusions are missing. Indeed, caloric restriction without malnutrition is associated to cancer prevention. Food may be also the primary route of exposure to contaminants such as metals, persistent organic pollutants, and pesticides. Exposuredisease associations and the interplay with genetic susceptibility requires further studies on genetic variation, environment, lifestyle, and chronic disease in order to eliminate and reduce associated health risks, thus contributing to improve health outcomes for the population. A primary nutritional approach for Active and Healthy Ageing (AHA) has been developed by the Nutrition group of the European Innovation Partnership (EIP) on AHA. The working group on lifestyles of the Italian Ministry of Health has developed a comprehensive approach to adequate nutrition using a consensus methodology to collect and integrate the available evidences from the literature and from the Italian experiences at the regional level, to raise the interest of other experts and relevant stakeholders to outline and scale-up joint strategies for a primary nutritional approach to cancer prevention.
authors.affiliation: ARS Regione Marche, Federico II University, and R&D Unit, Federico II University Hospital.
authors.forename: L
authors.initials: L
authors.lastname: Di Furia
authors.affiliation: Department of Translational Medical Sciences, Federico II University, and R&D Unit, Federico II University Hospital.
authors.forename: M R
authors.initials: MR
authors.lastname: Rusciano
authors.affiliation: Regione del Veneto - Progetto Mattone Internazionale.
authors.forename: L
authors.initials: L
authors.lastname: Leonardini
authors.affiliation: Ministero della Salute, Direzione generale della comunicazione e dei rapporti europei e internazionali.
authors.forename: P
authors.initials: P
authors.lastname: Rossi
authors.affiliation: ARS Regione Marche, Federico II University, and R&D Unit, Federico II University Hospital.
authors.forename: C
authors.initials: C
authors.lastname: Giammarchi
authors.affiliation: ARS Regione Marche, Federico II University, and R&D Unit, Federico II University Hospital.
authors.forename: E
authors.initials: E
authors.lastname: Vittori
authors.affiliation: ASL8 Regione Sardegna.
authors.forename: S
authors.initials: S
authors.lastname: Tilocca
authors.affiliation: ASL Salerno regione Campania.
authors.forename: F L
authors.initials: FL
authors.lastname: Russo
authors.affiliation: Dipartimento di Sanità Pubblica, Università Federico II.
authors.forename: P
authors.initials: P
authors.lastname: Montuori
authors.affiliation: Dipartimento di Sanità Pubblica, Università Federico II.
authors.forename: M
authors.initials: M
authors.lastname: Triassi
authors.affiliation: Dipartimento di Sanità Pubblica, Università Federico II.
authors.forename: A
authors.initials: A
authors.lastname: Nardone
authors.affiliation: Direzione salute e coesione sociale- Regione Umbria.
authors.forename: M D
authors.initials: MD
authors.lastname: Giaimo
authors.affiliation: Servizio Epidemiologia Clinica e ValutativaAPSS - Trento.
authors.forename: M
authors.initials: M
authors.lastname: Migazzi
authors.affiliation: Servizio Epidemiologia Clinica e ValutativaAPSS - Trento.
authors.forename: S
authors.initials: S
authors.lastname: Piffer
authors.affiliation: Regione Calabria.
authors.forename: A
authors.initials: A
authors.lastname: Iaria
authors.affiliation: Regione Calabria.
authors.forename: A
authors.initials: A
authors.lastname: Trapasso
authors.affiliation: Università degli studi di Palermo Dipartimento di Scienze per la promozione della salute e materno Infantile (DSPSMI) "Giuseppe D'Alessandro"
authors.forename: A
authors.initials: A
authors.lastname: Firenze
authors.affiliation: Azienda USL della Valle d'Aosta.
authors.forename: R
authors.initials: R
authors.lastname: Cristaudo
authors.affiliation: Regione Piemonte.
authors.forename: M
authors.initials: M
authors.lastname: Revello
authors.affiliation: Azienda USL della Valle d'Aosta.
authors.forename: A
authors.initials: A
authors.lastname: Castiglion
authors.affiliation: U.O.C. Oncologia Medica 1, Istituto Oncologico Veneto, IRCCS, Padova.
authors.forename: V
authors.initials: V
authors.lastname: Zagonel
authors.affiliation: Dipartimento di Medicina e Chirurgia, Università di Salerno.
authors.forename: G
authors.initials: G
authors.lastname: Iaccarino
authors.affiliation: Agenzia sanitaria e sociale regionale-Assr Emilia-Romagna.
authors.forename: A
authors.initials: A
authors.lastname: Addis
authors.affiliation: Dipartimento Salute e Risorse Naturali - Regione Campania.
authors.forename: L
authors.initials: L
authors.lastname: Natale
authors.affiliation: IRCCS SDN Napoli, Universita' Federico.
authors.forename: C
authors.initials: C
authors.lastname: Di Somma
authors.affiliation: Dipartimento Di Medicina Clinica E Chirurgia, Sezione Di Endocrinologia, Universita' Federico.
authors.forename: A
authors.initials: A
authors.lastname: Colao
authors.affiliation: Istituto Superiore di Sanita, Roma.
authors.forename: A
authors.initials: A
authors.lastname: Perra
authors.affiliation: ASL Napoli 3 Sud Regione Campania.
authors.forename: K
authors.initials: K
authors.lastname: Giova
authors.affiliation: Department of Translational Medical Sciences, Federico II University, and R&D Unit, Federico II University Hospital.
authors.forename: N
authors.initials: N
authors.lastname: Montuori
authors.affiliation: Department of Translational Medical Sciences, Federico II University, and R&D Unit, Federico II University Hospital; Reference Site Campania EIP on AHA-AOU Federico II UOS Ricerca e Sviluppo.
authors.forename: M
authors.initials: M
authors.lastname: Illario
keywords: Nutritional interventions; cancer prevention; lifestyle and cancer risk