title: Drug-laden 3D biodegradable label using QR code for anti-counterfeiting of drugs.
abstract: Wiping out counterfeit drugs is a great task for public health care around the world. The boost of these drugs makes treatment to become potentially harmful or even lethal. In this paper, biodegradable drug-laden QR code label for anti-counterfeiting of drugs is proposed that can provide the non-fluorescence recognition and high capacity. It is fabricated by the laser cutting to achieve the roughness over different surface which causes the difference in the gray levels on the translucent material the QR code pattern, and the micro mold process to obtain the drug-laden biodegradable label. We screened biomaterials presenting the relevant conditions and further requirements of the package. The drug-laden microlabel is on the surface of the troches or the bottom of the capsule and can be read by a simple smartphone QR code reader application. Labeling the pill directly and decoding the information successfully means more convenient and simple operation with non-fluorescence and high capacity in contrast to the traditional methods.
authors.affiliation: Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Fei
authors.affiliation: Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China. Electronic address: liuran@tsinghua.edu.cn.
authors.forename: Ran
authors.initials: R
authors.lastname: Liu
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry / Q000378:metabolism*; D040421:Cell Phone; D004348:Drug Labeling / Q000379:methods*; D007091:Image Processing, Computer-Assisted; D054020:Lasers, Gas; D019904:Polymethyl Methacrylate / Q000737:chemistry
chemical_list: D001672:Biocompatible Materials; D019904:Polymethyl Methacrylate
keywords: Anti-counterfeiting; Drug-laden biodegradable label; Identification; QR code