title: MR findings of Lynch syndrome-related uterine endometrial carcinoma: a case report.
abstract: A 41-year-old woman presented with atypical genital bleeding. Magnetic resonance imaging demonstrated a polypoid mass from the lower uterine segment to cervical canal, approximately 32 mm in size. Additionally, a thickened sigmoid colon wall showing a markedly high signal intensity on diffusion-weighted imaging was observed. Barium enema and colonoscopy revealed a type I sigmoid colon cancer. Since this patient was relatively young and had multiple relatives with colon cancer, Lynch syndrome was suspected and proved by an immunohistochemical survey. Uterine endometrial carcinoma related to Lynch syndrome tends to occur in the lower uterine segment. Radiologists should be aware of this syndrome so that the correct diagnosis can be suggested in the imaging report.
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan. kiyo829@hotmail.co.jp.
authors.forename: Kiyoyuki
authors.initials: K
authors.lastname: Minamiguchi
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Takahama
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Nagaaki
authors.initials: N
authors.lastname: Marugami
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Aki
authors.initials: A
authors.lastname: Marugami
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Masayo
authors.initials: M
authors.lastname: Haga
authors.affiliation: Department of Radiology, Heisei Memorial Hospital, 827 Shijo-cho, Kashihara, Nara, 634-0813, Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Takewa
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Itoh
authors.affiliation: Department of Radiology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Kimihiko
authors.initials: K
authors.lastname: Kichikawa
authors.affiliation: Department of Diagnostic Pathology, Nara Medical University, 850 Shijo-cho, Kashihara, Nara, 634-8522, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Uchiyama
mesh_terms: D000328:Adult; D012809:Colon, Sigmoid; D003113:Colonoscopy; D003123:Colorectal Neoplasms, Hereditary Nonpolyposis; D016889:Endometrial Neoplasms; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging
keywords: Endometrial carcinoma; Lynch syndrome; MRI