title: Hydroxylation and Glycosylation of Phenylpropanoids by Cultured Cells of Phytolacca americana.
abstract: Hydroxylation and glycosylation of cinnamic acid, p-coumaric acid, caffeic acid, and ferulic acid were investigated using cultured plant cells of Phytolacca americana as biocatalysts. Regioselective hydroxylation at the 4-position of cinnamic acid and 3-position of p-coumaric acid was observed. Although cinnamic acid was transformed to mono-glucoside products, di-glycosylation occurred in the case of the biotransformation of p-coumaric acid, caffeic acid, and ferulic acid.
authors.forename: Kei
authors.initials: K
authors.lastname: Shimoda
authors.forename: Naoji
authors.initials: N
authors.lastname: Kubota
authors.forename: Daisuke
authors.initials: D
authors.lastname: Uesugi
authors.forename: Masato
authors.initials: M
authors.lastname: Tanigawa
authors.forename: Hiroki
authors.initials: H
authors.lastname: Hamada
mesh_terms: D001711:Biotransformation; D002478:Cells, Cultured; D002934:Cinnamates / Q000737:chemistry*; D003373:Coumaric Acids / Q000737:chemistry*; D006031:Glycosylation; D006900:Hydroxylation; D015394:Molecular Structure; D029604:Phytolacca americana / Q000166:cytology* / Q000378:metabolism*; D011422:Propionates
chemical_list: D002934:Cinnamates; D003373:Coumaric Acids; D011422:Propionates; C029010:cinnamic acid; C004999:ferulic acid; C495469:p-coumaric acid