title: Options in Prophylactic Surgery to Prevent Ovarian Cancer in High-Risk Women: How New Hypotheses of Fallopian Tube Origin Influence Recommendations.
abstract: In women at increased risk of developing ovarian cancer, risk-reducing salpingo-oophorectomy is the only intervention that has been shown to decrease mortality from ovarian cancer and is the standard of care for risk reduction. Prophylactic salpingectomy with delayed oophorectomy should be considered in high-risk premenopausal women in the setting of a clinical trial.
authors.affiliation: Department of Obstetrics and Gynecology, Division of Gynecologic Surgery, Mayo Clinic, Eisenberg Lobby 71, 200 First Street SW, Rochester, MN, 55905, USA.
authors.forename: Casey L
authors.initials: CL
authors.lastname: Swanson
authors.affiliation: Department of Obstetrics and Gynecology, Division of Gynecologic Surgery, Mayo Clinic, Eisenberg Lobby 71, 200 First Street SW, Rochester, MN, 55905, USA. bakkum.jamie@mayo.edu.
authors.forename: Jamie N
authors.initials: JN
authors.lastname: Bakkum-Gamez
mesh_terms: D005187:Fallopian Tubes / Q000601:surgery*; D005260:Female; D006801:Humans; D010051:Ovarian Neoplasms / Q000517:prevention & control*; D010052:Ovariectomy; D017697:Premenopause; D012307:Risk Factors; D013246:Sterilization, Tubal
keywords: BRCA; Fimbriectomy; Hereditary breast and ovarian cancer syndrome; Oophorectomy; Ovarian cancer; Salpingectomy