title: DISSEMINATED FUNGAL INFECTION WITH ADRENAL INVOLVEMENT: REPORT OF TWO HIV NEGATIVE BRAZILIAN PATIENTS.
abstract: Paracoccidioidomycosis and histoplasmosis are systemic fungal infections endemic in Brazil. Disseminated clinical forms are uncommon in immunocompetent individuals. We describe two HIV-negative patients with disseminated fungal infections, paracoccidioidomycosis and histoplasmosis, who were diagnosed by biopsies of suprarenal lesions. Both were treated for a prolonged period with oral antifungal agents, and both showed favorable outcomes.
authors.affiliation: Departamento de Doenças Infecciosas, Hospital Edmundo Vasconcelos, São Paulo, SP, Brasil, ghpereira@terra.com.br; elisa.m.beirao@gmail.com; artur.timerman@globo.com.
authors.forename: Graziella Hanna
authors.initials: GH
authors.lastname: Pereira
authors.affiliation: Departamento de Patologia, Hospital Edmundo Vasconcelos, São Paulo, SP, Brasil, vlanzoni@unifesp.br.
authors.forename: Valéria Pereira Barbosa
authors.initials: VP
authors.lastname: Lanzoni
authors.affiliation: Departamento de Doenças Infecciosas, Hospital Edmundo Vasconcelos, São Paulo, SP, Brasil, ghpereira@terra.com.br; elisa.m.beirao@gmail.com; artur.timerman@globo.com.
authors.forename: Elisa Maria
authors.initials: EM
authors.lastname: Beirão
authors.affiliation: Departamento de Doenças Infecciosas, Hospital Edmundo Vasconcelos, São Paulo, SP, Brasil, ghpereira@terra.com.br; elisa.m.beirao@gmail.com; artur.timerman@globo.com.
authors.forename: Artur
authors.initials: A
authors.lastname: Timerman
authors.affiliation: Instituto Adolfo Lutz, São Paulo, SP, Brasil, melhemmr@uol.com.br.
authors.forename: Marcia de Souza Carvalho
authors.initials: Mde S
authors.lastname: Melhem
mesh_terms: D000307:Adrenal Gland Diseases / Q000175:diagnosis* / Q000382:microbiology; D001706:Biopsy; D001938:Brazil; D020314:Central Nervous System Fungal Infections / Q000175:diagnosis* / Q000382:microbiology; D005148:Facial Dermatoses / Q000175:diagnosis* / Q000382:microbiology; D006660:Histoplasmosis / Q000175:diagnosis*; D006801:Humans; D007121:Immunocompetence / Q000502:physiology; D008297:Male; D008875:Middle Aged; D010229:Paracoccidioidomycosis / Q000175:diagnosis*