title: Conflict-Related Anterior Cingulate Functional Connectivity Is Associated With Past Suicidal Ideation and Behavior in Recent-Onset Psychotic Major Mood Disorders.
abstract: Suicidal ideation and behavior are highly prevalent in psychotic major mood disorders, yet their relationship to brain function remains unclear. Thirty patients with recent-onset of bipolar disorder type I (N=21) or major depressive disorder (N=9) with past psychosis were evaluated for past suicidal ideation/behavior and functional MRI during conflict-monitoring. Suicidal ideation was related to relatively higher dorsal anterior cingulate cortex (dACC)-seeded functional connectivity with dorsal fronto-parietal and inferior temporal-occipital cortex, as well as lower dACC connectivity with bilateral ventrolateral prefrontal cortex (PFC) and adjacent fronto-striatal regions. Past suicidal behavior was associated with lower dACC functional connectivity with dorsolateral PFC and premotor cortex, as well as temporal-parietal cortex.
authors.affiliation: From the Dept. of Psychiatry, UC, San Francisco School of Medicine, San Francisco, CA (MJM, YC); the Center for Neuroscience, UC, Davis, Davis, CA (TAL); and the Dept. of Psychiatry, UC, Davis School of Medicine, Sacramento, CA (TAN, CSC).
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Minzenberg
authors.affiliation: From the Dept. of Psychiatry, UC, San Francisco School of Medicine, San Francisco, CA (MJM, YC); the Center for Neuroscience, UC, Davis, Davis, CA (TAL); and the Dept. of Psychiatry, UC, Davis School of Medicine, Sacramento, CA (TAN, CSC).
authors.forename: Tyler A
authors.initials: TA
authors.lastname: Lesh
authors.affiliation: From the Dept. of Psychiatry, UC, San Francisco School of Medicine, San Francisco, CA (MJM, YC); the Center for Neuroscience, UC, Davis, Davis, CA (TAL); and the Dept. of Psychiatry, UC, Davis School of Medicine, Sacramento, CA (TAN, CSC).
authors.forename: Tara A
authors.initials: TA
authors.lastname: Niendam
authors.affiliation: From the Dept. of Psychiatry, UC, San Francisco School of Medicine, San Francisco, CA (MJM, YC); the Center for Neuroscience, UC, Davis, Davis, CA (TAL); and the Dept. of Psychiatry, UC, Davis School of Medicine, Sacramento, CA (TAN, CSC).
authors.forename: Yaoan
authors.initials: Y
authors.lastname: Cheng
authors.affiliation: From the Dept. of Psychiatry, UC, San Francisco School of Medicine, San Francisco, CA (MJM, YC); the Center for Neuroscience, UC, Davis, Davis, CA (TAL); and the Dept. of Psychiatry, UC, Davis School of Medicine, Sacramento, CA (TAN, CSC).
authors.forename: Cameron S
authors.initials: CS
authors.lastname: Carter