title: First Case Report of Acute Renal Failure After Mesh-Plug Inguinal Hernia Repair in a Kidney Transplant Recipient.
abstract: Acute renal failure due to ureter compression after a mesh-plug inguinal repair in a kidney transplant recipient has not been previously reported to our knowledge. A 62-year-old man, who successfully underwent kidney transplantation from a deceased donor 6 years earlier, was admitted for elective repair of a direct inguinal hernia. The patient underwent an open mesh-plug repair of the inguinal hernia with placement of a plug in the preperitoneal space. We did not observe the transplanted ureter and bladder during dissection of the inguinal canal. Immediately after surgery, the patient became anuric, and a graft sonography demonstrated massive hydronephrosis. The serum creatinine level increased rapidly, and the patient underwent an emergency reoperation 8 hours later. During surgery, we did not identify the ureter but, immediately after plug removal, urine output increased progressively. We completed the hernia repair using the standard technique, without plug interposition, and the postoperative course was uneventful with complete resolution of graft dysfunction 3 days later. Furthermore, we reviewed the clinical features of complications related to inguinal hernia surgery. An increased risk of urological complications was reported recently in patients with a previous prosthetic hernia repair undergoing kidney transplantation, mainly due to the mesh adhesion to surrounding structures, making the extraperitoneal dissection during the transplant surgery very challenging. Moreover, older male kidney transplant recipients undergoing an inguinal hernia repair may be at higher risk of graft dysfunction due to inguinal herniation of a transplanted ureter. Mesh-plug inguinal hernia repair is a safe surgical technique, but this unique case suggests that kidney transplant recipients with inguinal hernia may be at higher risk of serious urological complications. Surgeons must be aware of the graft and ureter position before proceeding with hernia repair. A prompt diagnosis with graft sonography and abdominal computed tomography scan and emergency surgery may avoid the need for nephrostomy and may resolve graft dysfunction more rapidly.
authors.affiliation: From the Vascular Surgery and Organ Transplant Unit (MV, VA, DZ, PC, NS, AG, PV), Department of Medical and Surgical Sciences and Advanced Technologies; and Radiodiagnostic and Radiotherapy Unit (SP), University Hospital of Catania, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Veroux
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ardita
authors.forename: Domenico
authors.initials: D
authors.lastname: Zerbo
authors.forename: Pietro
authors.initials: P
authors.lastname: Caglià
authors.forename: Stefano
authors.initials: S
authors.lastname: Palmucci
authors.forename: Nunziata
authors.initials: N
authors.lastname: Sinagra
authors.forename: Alessia
authors.initials: A
authors.lastname: Giaquinta
authors.forename: Pierfrancesco
authors.initials: P
authors.lastname: Veroux
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology*; D006552:Hernia, Inguinal / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007677:Kidney Function Tests; D016030:Kidney Transplantation / Q000009:adverse effects; D008297:Male; D011183:Postoperative Complications / Q000209:etiology*; D012086:Reoperation; D013526:Surgical Mesh / Q000009:adverse effects*