title: Clinicopathologic Correlation of White, Non scrapable Oral Mucosal Surface Lesions: A Study of 100 Cases.
abstract: BACKGROUND
  White, non scrapable lesions are commonly seen in the oral cavity. Based on their history and clinical appearance, most of these lesions can be easily diagnosed, but sometimes diagnosis may go wrong. In order to arrive to a confirmative diagnosis, histopathological assessment is needed in many cases, if not all.
  
  
  OBJECTIVE
  1) To find out the prevalence of clinically diagnosed oral white, non scrapable lesions. 2) To find out the prevalence of histopathologically diagnosed oral white, non scrapable lesions. 3) To correlate the clinical and histopathological diagnosis in the above lesions.
  
  
  METHODS
  A total of 100 cases of oral white, non scrapable lesions were included in the study. Based on their history and clinical presentation, clinical provisional diagnosis was made. Then biopsy was done and confirmatory histopathological diagnosis was given and both were correlated. In order to correlate clinical and histopathological diagnosis Discrepancy Index (DI) was calculated for all the cases.
  
  
  RESULTS
  Based on clinical diagnosis, there were 59 cases (59%) of leukoplakia, 29 cases (29%) of lichen planus and six cases (6%) of lichenoid reaction; whereas, based on histopathological diagnosis, there were 66 cases (66%) of leukoplakia epithelial hyperplasia and hyperkeratosis (leukoplakia) and 30 cases (30%) of lichen planus. Seventy eight clinically diagnosed cases (78%) correlated with the histopathological diagnosis and 22 cases (22%) did not correlate. The total discrepancy index was 22%.
  
  
  CONCLUSIONS
  A clinician needs to be aware of oral white, non scrapable lesions. Due to the overlapping of many clinical features in some of these lesions and also due to their malignant potential, a histopathological confirmative diagnosis is recommended.
authors.affiliation: Assistant Professor, Department of Oral & Maxillofacial Pathology, S.B Patil Dental College and Hospital , Bidar, Karnataka, India .
authors.forename: Mohammed
authors.initials: M
authors.lastname: Abidullah
authors.affiliation: Professor and HOD, Department of Oral & Maxillofacial Pathology, Narayana Dental College & Hospital , Nellore, AP, India .
authors.forename: Vandana
authors.initials: V
authors.lastname: Raghunath
authors.affiliation: Professor, Department of Oral & Maxillofacial Surgery, S.B Patil Dental College and Hospital , Bidar, Karnataka, India .
authors.forename: Tanveer
authors.initials: T
authors.lastname: Karpe
authors.affiliation: Reader, Department of Oral & Maxillofacial Surgery, Daswani Dental College & Hospital , Kota, Rajasthan, India .
authors.forename: Syed
authors.initials: S
authors.lastname: Akifuddin
authors.affiliation: Post Graduate Student, Department of Oral Medicine & Radiology, MNR Dental College , Sanga Reddy, Telagana, India .
authors.forename: Shahid
authors.initials: S
authors.lastname: Imran
authors.affiliation: Graduate Student, Ragas Dental College , Chennai, Tamil Nadu, India .
authors.forename: Venkata Naga Nalini
authors.initials: VN
authors.lastname: Dhurjati
authors.affiliation: Consulting Oral & Maxillofacial Surgeon, Life Prime Dental Hospital , Hyderabad, Telangana, India .
authors.forename: Mohammed Ahtesham
authors.initials: MA
authors.lastname: Aleem
authors.affiliation: Director, Dentomax Dental & Maxillofacial Solutions , Hyderabad, Telangana, India .
authors.forename: Farheen
authors.initials: F
authors.lastname: Khatoon
keywords: Frictional keratosis; Leukoedema; Leukoplakia; Lichen planus; Lichenoid reaction