title: Infantile Respiratory Distress Syndrome and Its Probable Links With Parameters of the Maternal Patient History: A Forensic Case Report.
abstract: Respiratory distress syndrome (RDS) has a major contribution to neonatal mortality worldwide. Multiple factors associated with increased risk for RDS have been documented to effectively understand the emergence and progression of this disorder. A portion of these parameters has been broadly examined whereas the role of others, despite being clinically described, has not been fully evaluated. In this report, we analyze a forensic RDS case of a late preterm infant. Taking the maternal medical history into account, we focused on 2 not widely established risk factors, oligohydramnios and maternal age, discussing their possible pathophysiological relation to the development of RDS. Simultaneously, the fundamental role of the histopathological examination as a diagnostic tool resurfaces. Following a multidisciplinary approach derived from the collaboration of clinicians and researchers, the identification of factors that precipitate or contribute to this syndrome can be enhanced, leading to novel prognostic and therapeutic strategies against RDS.
authors.affiliation: From the *School of Medicine, Faculty of Health Sciences, and †Laboratory of Forensic Medicine and Toxicology, Medical School, Aristotle University of Thessaloniki, Thessaloniki; and ‡Laboratory of Forensic Medicine, Medical School, Democritus University of Thrace, Komotini, Greece.
authors.forename: Charilaos
authors.initials: C
authors.lastname: Giannitsis
authors.forename: Asterios
authors.initials: A
authors.lastname: Arampatzis
authors.forename: Maria
authors.initials: M
authors.lastname: Stefanidou
authors.forename: Doxakis
authors.initials: D
authors.lastname: Anestakis
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Raikos
authors.forename: Pavlos
authors.initials: P
authors.lastname: Pavlidis
mesh_terms: D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007235:Infant, Premature, Diseases; D008168:Lung / Q000473:pathology; D008423:Maternal Age; D016104:Oligohydramnios; D011247:Pregnancy; D012127:Respiratory Distress Syndrome, Newborn / Q000473:pathology*; D012307:Risk Factors