title: Laparoscopic Resection of Recurrence from Hepatocellular Carcinoma after Liver Transplantation: Case Reports and Review of the Literature.
abstract: Background. Recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) indicates a poor prognosis. Surgery is considered the only curative option for selected patients with HCC recurrence following LT. Traditionally, the preference is given to the open approach. Methods. In this report, we present two cases of laparoscopic resections (LR) for recurrent HCC after LT, performed at Oslo University Hospital, Rikshospitalet. Results. Both procedures were executed without intraoperative and postoperative adverse events. Whereas one of the patients had a recurrence one year after LR, the other patient did not have any sign of disease during 3-year follow-up. Conclusions. We argue that, in selected cases, patients with HCC recurrence following LT may benefit from LR due to its limited tissue trauma and timely start of subsequent treatment if curative resection cannot be obtained. In patients with relatively favorable prognosis, LR facilitates postoperative recovery course and avoids unnecessary laparotomy.
authors.affiliation: The Intervention Centre, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway; Institute of Clinical Research, Medical Faculty, University of Oslo, 0318 Oslo, Norway; Department of Surgery No. 1, Yerevan State Medical University after M. Heratsi, 0025 Yerevan, Armenia.
authors.forename: Mushegh A
authors.identifier: 0000-0002-4815-7694
authors.initials: MA
authors.lastname: Sahakyan
authors.affiliation: The Intervention Centre, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway; Department of Gastrointestinal Surgery, Akershus University Hospital, 1478 Lørenskog, Norway.
authors.forename: Airazat M
authors.initials: AM
authors.lastname: Kazaryan
authors.affiliation: Department of HPB Surgery, Oslo University Hospital, Rikshospitalet, 0407 Oslo, Norway.
authors.forename: Ewa
authors.initials: E
authors.lastname: Pomianowska
authors.affiliation: Department of Radiology, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway.
authors.forename: Andreas
authors.initials: A
authors.lastname: Abildgaard
authors.affiliation: Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, 0424 Oslo, Norway.
authors.forename: Pål-Dag
authors.initials: PD
authors.lastname: Line
authors.affiliation: Department of HPB Surgery, Oslo University Hospital, Rikshospitalet, 0407 Oslo, Norway.
authors.forename: Bjørn Atle
authors.initials: BA
authors.lastname: Bjørnbeth
authors.affiliation: The Intervention Centre, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway; Institute of Clinical Research, Medical Faculty, University of Oslo, 0318 Oslo, Norway; Department of HPB Surgery, Oslo University Hospital, Rikshospitalet, 0407 Oslo, Norway.
authors.forename: Bjørn
authors.initials: B
authors.lastname: Edwin
authors.affiliation: Department of HPB Surgery, Oslo University Hospital, Rikshospitalet, 0407 Oslo, Norway.
authors.forename: Bård Ingvald
authors.initials: BI
authors.lastname: Røsok