title: New 6,6-Spiroketal from the Alga-Derived Fungus Penicillium lividum.
abstract: The new 6,6-spiroketal,sargassopenilline H (1), and known peneciraistin C (2) have been isolated from an EtOAc extract of the marine-derived fungus Penicillium lividumKMM 4663. The structure of the new metabolite was determined by HR ESIMS and 1D and 2D NMR spectroscopy. Sargassopenilline H (1) in non-cytotoxic concentration inhibited colony formation of RPMI-7951 and MDA-MB-231 cell lines.
authors.forename: Olesya I
authors.initials: OI
authors.lastname: Zhuravleva
authors.forename: Maria P
authors.initials: MP
authors.lastname: Sobolevskaya
authors.forename: Vladimir A
authors.initials: VA
authors.lastname: Denisenko
authors.forename: Natalya N
authors.initials: NN
authors.lastname: Kirichuk
authors.forename: Maxim E
authors.initials: ME
authors.lastname: Zhidkov
authors.forename: Svetlana P
authors.initials: SP
authors.lastname: Ermakova
authors.forename: Natalya Yu
authors.initials: NY
authors.lastname: Kim
authors.forename: Alekxandr S
authors.initials: AS
authors.lastname: Antonov
authors.forename: Elena V
authors.initials: EV
authors.lastname: Leshchenko
authors.forename: Shamil Sh
authors.initials: SSh
authors.lastname: Afiyatullov
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology; D001578:Benzopyrans / Q000737:chemistry* / Q000494:pharmacology*; D045744:Cell Line, Tumor; D049109:Cell Proliferation / Q000187:drug effects; D006801:Humans; D015394:Molecular Structure; D010407:Penicillium / Q000737:chemistry*; D013141:Spiro Compounds / Q000737:chemistry* / Q000494:pharmacology*
chemical_list: D000970:Antineoplastic Agents; D001578:Benzopyrans; D013141:Spiro Compounds; C587960:peneciraistin C; C000607233:sargassopenilline H