title: The burden of cutaneous melanoma and status of preventive measures in Central and South America.
abstract: OBJECTIVE
  Very little is known about the burden of cutaneous melanoma in Central and South America, despite the existence of a reasonable amount of population-based data. We present data on melanoma incidence calculated in a standardized way for Central and South America, as well as an overview of primary and secondary prevention issues in the region.
  
  
  METHODS
  Cancer registry data on all incident cases reported in the different registries present in Central and South America were combined to provide registry-based country estimates of age-standardized, sex-specific cutaneous melanoma incidence overall, and by histological subtype and anatomical site. A literature search provided additional information.
  
  
  RESULTS
  Age-standardized incidence rates were between 1 and 5 per 100,000 and tended to be higher further away from the equator. Cutaneous melanomas of the acral type, mostly occurring on the lower limbs, are a distinguishing feature of melanoma in Central and South America in comparison with high-incidence areas. Several preventive measures, both primary and secondary, are in place, albeit largely without evaluation.
  
  
  CONCLUSIONS
  Due to incomplete registration and different registration practices, reliable and comparable data on melanoma were difficult to obtain; thus it is likely that the true burden of melanoma in Central and South America has been underestimated. The different characteristics of the cutaneous melanoma patient population in terms of anatomical site and histological type distribution imply a need for adapted primary and secondary prevention measures. The generally high ambient ultraviolet radiation levels require sufficient sun protection measures.
authors.affiliation: International Agency for Research on Cancer, Section of Cancer Surveillance, Lyon, France; National Cancer Institute, Directorate of Research, Surveillance, Prevention and Promotion, Colombia; Erasmus MC University Medical Center, Department of Public Health, Rotterdam, The Netherlands. Electronic address: estherdevries77@gmail.com.
authors.forename: Esther
authors.initials: E
authors.lastname: de Vries
authors.affiliation: International Agency for Research on Cancer, Section of Cancer Surveillance, Lyon, France.
authors.forename: Mónica
authors.initials: M
authors.lastname: Sierra
authors.affiliation: International Agency for Research on Cancer, Section of Cancer Surveillance, Lyon, France.
authors.forename: Marion
authors.initials: M
authors.lastname: Piñeros
authors.affiliation: Argentinian Registry of Cutaneous Melanoma, Argentina.
authors.forename: Dora
authors.initials: D
authors.lastname: Loria
authors.affiliation: International Agency for Research on Cancer, Section of Cancer Surveillance, Lyon, France.
authors.forename: David
authors.initials: D
authors.lastname: Forman
keywords: Central and South America; Incidence; Melanoma; Prevention