title: Patellofemoral Osteoarthritis: Are We Missing an Important Source of Symptoms After Anterior Cruciate Ligament Reconstruction?
abstract: Anterior cruciate ligament (ACL) rupture is a well-established risk factor for knee osteoarthritis (OA). Fifty to ninety percent of individuals will develop radiographic tibiofemoral OA within a decade after ACL injury and anterior cruciate ligament reconstruction (ACLR). Although less well recognized, radiographic patellofemoral OA is present in approximately 50% of individuals at more than 10 years after ACLR. This early-onset OA and its associated pain and functional limitations pose a particular challenge to younger adults with OA compared to an older OA population. Targeted interventions need to be developed to reduce the burden of early-onset OA following ACLR. Emerging evidence suggests that such interventions should target both the patellofemoral and tibiofemoral joints.
authors.forename: Adam G
authors.initials: AG
authors.lastname: Culvenor
authors.forename: Kay M
authors.initials: KM
authors.lastname: Crossley
mesh_terms: D000328:Adult; D000070598:Anterior Cruciate Ligament Injuries / Q000150:complications* / Q000503:physiopathology / Q000601:surgery*; D059549:Anterior Cruciate Ligament Reconstruction / Q000009:adverse effects* / Q000534:rehabilitation; D001696:Biomechanical Phenomena; D001915:Braces; D006801:Humans; D020370:Osteoarthritis, Knee / Q000209:etiology* / Q000503:physiopathology; D057071:Patellofemoral Joint / Q000503:physiopathology*; D026741:Physical Therapy Modalities; D011183:Postoperative Complications; D012307:Risk Factors
keywords: ACL; ACLR; OA; age; anterior cruciate ligament; knee osteoarthritis; patellofemoral osteoarthritis; tibial osteoarthritis