title: Perisaccadic Receptive Field Expansion in the Lateral Intraparietal Area.
abstract: Humans and monkeys have access to an accurate representation of visual space despite a constantly moving eye. One mechanism by which the brain accomplishes this is by remapping visual receptive fields around the time of a saccade. In this process a neuron can be excited by a probe stimulus in the current receptive field, and also simultaneously by a probe stimulus in the location that will be brought into the neuron's receptive field by the saccade (the future receptive field), even before saccade begins. Here we show that perisaccadic neuronal excitability is not limited to the current and future receptive fields but encompasses the entire region of visual space across which the current receptive field will be swept by the saccade. A computational model shows that this receptive field expansion is consistent with the propagation of a wave of activity across the cerebral cortex as saccade planning and remapping proceed.
authors.affiliation: Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Kavli Institute for Neuroscience, Columbia University, New York, NY 10032, USA.
authors.forename: Xiaolan
authors.initials: X
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China; Department of Physics, The Hong Kong University of Science and Technology, Clear Water, Hong Kong, China.
authors.forename: C C Alan
authors.initials: CC
authors.lastname: Fung
authors.affiliation: Department of Neuroscience, Brown University, Providence, RI 02912, USA.
authors.forename: Shaobo
authors.initials: S
authors.lastname: Guan
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China. Electronic address: wusi@bnu.edu.cn.
authors.forename: Si
authors.initials: S
authors.lastname: Wu
authors.affiliation: Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Mahoney-Keck Center for Brain and Behavior Research, Department of Neuroscience, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Departments of Neurology, Psychiatry, and Ophthalmology, College of Physicians and Surgeons, Columbia University, New York, NY 10032, USA; Kavli Institute for Neuroscience, Columbia University, New York, NY 10032, USA; Division of Neurobiology and Behavior, New York State Psychiatric Institute, New York, NY 10032, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Goldberg
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning, IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing 100875, China. Electronic address: mingsha.zhang@bnu.edu.cn.
authors.forename: Mingsha
authors.initials: M
authors.lastname: Zhang
mesh_terms: D000818:Animals; D008253:Macaca mulatta; D008959:Models, Neurological; D009474:Neurons / Q000502:physiology; D010296:Parietal Lobe / Q000502:physiology*; D010775:Photic Stimulation; D012438:Saccades / Q000502:physiology*; D014794:Visual Fields / Q000502:physiology*