title: Diagnosis of Choroidal Melanoma in Dense Asteroid Hyalosis.
abstract: OBJECTIVE
  To demonstrate the utility of Optos ultra-wide field imaging in the diagnosis and management of choroidal melanoma in the setting of asteroid hyalosis.
  
  
  METHODS
  Observational case report.
  
  
  METHODS
  A 52-year-old female was referred for evaluation of floaters, photopsias, and blurry vision in the right eye. Clinical examination revealed dense asteroid hyalosis obscuring the fundus, and a limited view of a pigmented choroidal lesion in the nasal periphery. Optos ultra-wide field fluorescein angiography and ultrasonography facilitated the diagnosis of a choroidal melanoma.
  
  
  RESULTS
  The patient underwent Iodine-125 brachytherapy for local tumor control and excellent tumor response was confirmed with serial follow-up Optos imaging and ultrasonography.
  
  
  CONCLUSIONS
  Ultra-wide field fundus fluorescein angiography facilitated the diagnosis of a choroidal melanoma, which was obscured by dense asteroid hyalosis, allowing for local tumor control with brachytherapy. Optos wide-field imaging may be a valuable tool for detecting potentially life-threatening lesions in the setting of asteroid hyalosis.
authors.affiliation: a Ophthalmic Oncology Center, Jules Stein Eye Institute, Department of Ophthalmology , University of California, Los Angeles (UCLA) , Los Angeles , CA , USA.
authors.forename: Meghna V
authors.initials: MV
authors.lastname: Motiani
authors.affiliation: a Ophthalmic Oncology Center, Jules Stein Eye Institute, Department of Ophthalmology , University of California, Los Angeles (UCLA) , Los Angeles , CA , USA.
authors.forename: Colin A
authors.initials: CA
authors.lastname: McCannel
authors.affiliation: a Ophthalmic Oncology Center, Jules Stein Eye Institute, Department of Ophthalmology , University of California, Los Angeles (UCLA) , Los Angeles , CA , USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Almanzor
authors.affiliation: a Ophthalmic Oncology Center, Jules Stein Eye Institute, Department of Ophthalmology , University of California, Los Angeles (UCLA) , Los Angeles , CA , USA.
authors.forename: Tara A
authors.initials: TA
authors.lastname: McCannel
mesh_terms: D001918:Brachytherapy; D002829:Choroid / Q000000981:diagnostic imaging*; D002830:Choroid Neoplasms / Q000175:diagnosis* / Q000532:radiotherapy; D003937:Diagnosis, Differential; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D008545:Melanoma / Q000175:diagnosis* / Q000532:radiotherapy; D008875:Middle Aged; D041623:Tomography, Optical Coherence
keywords: Choroidal melanoma; Optos; asteroid hyalosis; fluorescein angiography; ultrasonography; uveal melanoma