title: Objective Melanin Measurements: Review of Novel Dosimetry Guidance Device for Intense Pulsed Light in Aesthetic Treatments.
abstract: A melanin meter has been created to assess real time skin pigmentation to optimize settings for visible light aesthetic applications.
  
  
  METHODS
  A handheld meter was applied to non sun-damaged skin on the back of volunteers to measure skin pigmentation prior to treatment with IPL light sources over a range of pulse widths and ascending fluences. Curves for maximum epidermal tolerances as a function of pigmentation were determined. These curves were then tabulated for each pulse width in device software to provide guidance in the selection of fluences. Based on these findings, the device was applied in over 300 patients at a comprehensive laser and cosmetic dermatology center.
  
  
  RESULTS
  A pigment meter evaluation led to treatment parameter guidance in intense pulsed light applications. These suggested ranges for settings based on the melanin index score proved useful, accurate, and safe in applications over a broad range of skin colors and across various anatomic units of the skin.
  
  
  CONCLUSIONS
  A pigment meter can be used to identify appropriate settings with IPL treatments in order to enhance safety and efficacy when treating epidermal pigmented lesions, vessels, general photodamage and excessive hair (where the principles of selective photothermolysis are applied).
authors.forename: E Victor
authors.initials: EV
authors.lastname: Ross
authors.forename: Travis W
authors.initials: TW
authors.lastname: Blalock
authors.forename: Douglas
authors.initials: D
authors.lastname: Winstanley
authors.forename: Joel L
authors.initials: JL
authors.lastname: Cohen
authors.forename: James J
authors.initials: JJ
authors.lastname: Childs
mesh_terms: D003357:Cosmetic Techniques / Q000295:instrumentation*; D006801:Humans; D062325:Intense Pulsed Light Therapy / Q000295:instrumentation* / Q000379:methods*; D008543:Melanins / Q000032:analysis*; D010859:Pigmentation Disorders / Q000175:diagnosis* / Q000628:therapy*; D011880:Radiotherapy Planning, Computer-Assisted / Q000295:instrumentation / Q000379:methods; D015595:Skin Aging / Q000473:pathology; D016896:Treatment Outcome
chemical_list: D008543:Melanins