title: Actin'g against the Ball and Chain.
abstract: Spinocerebellar ataxia type 13 is a rare autosomal-dominant neurodegenerative disease induced by mutations in the voltage-dependent Kv3.3 potassium channel. Recently in Cell, Zhang et al. (2016) provide new insights into how Arp2/3-dependent actin polymerization modulates both Kv3.3 activity and its ability to stimulate actin polymerization via Hax-1.
authors.affiliation: Cellular Signalling and Cytoskeletal Function Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK.
authors.forename: Jasmine V G
authors.initials: JVG
authors.lastname: Abella
authors.affiliation: Cellular Signalling and Cytoskeletal Function Laboratory, The Francis Crick Institute, Lincoln's Inn Fields Laboratory, 44 Lincoln's Inn Fields, London WC2A 3LY, UK. Electronic address: michael.way@crick.ac.uk.
authors.forename: Michael
authors.initials: M
authors.lastname: Way
mesh_terms: D000199:Actins / Q000235:genetics*; D006801:Humans; D009154:Mutation; D051670:Shaw Potassium Channels; D013132:Spinocerebellar Degenerations
chemical_list: D000199:Actins; D051670:Shaw Potassium Channels