title: OrCanome: a Comprehensive Resource for Oral Cancer.
abstract: Oral cancer is one of the most prevalent cancers in India but the underlying mechanisms are minimally unraveled. Cancer research has immensely benefited from genome scale high throughput studies which have contributed to expanding the volume of data. Such datasets also exist for oral cancer genes but there has been no consolidated approach to integrate the data to reveal meaningful biological information. OrCanome is one of the largest and comprehensive, user-friendly databases of oral cancer. It features a compilation of over 900 genes dysregulated in oral cancer and provides detailed annotations of the genes, transcripts and proteins along with additional information encompassing expression, inhibitors, epitopes and pathways. The resource has been envisioned as a one-stop solution for genomic, transcriptomic and proteomic annotation of these genes and the integrated approach will facilitate the identification of potential biomarkers and therapeutic targets.
authors.affiliation: Biomedical Informatics Center, Institute of Cytology and Preventive Oncology, Noida, Uttar Pradesh, India E-mail : directoricpo@icmr.org.in, rmehrotra@icmr.org.in.
authors.forename: Deeksha
authors.initials: D
authors.lastname: Bhartiya
authors.forename: Amit
authors.initials: A
authors.lastname: Kumar
authors.forename: Harpreet
authors.initials: H
authors.lastname: Singh
authors.forename: Amitesh
authors.initials: A
authors.lastname: Sharma
authors.forename: Anita
authors.initials: A
authors.lastname: Kaushik
authors.forename: Suchitra
authors.initials: S
authors.lastname: Kumari
authors.forename: Ravi
authors.initials: R
authors.lastname: Mehrotra
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics* / Q000378:metabolism*; D019295:Computational Biology / Q000379:methods*; D016208:Databases, Factual; D023281:Genomics / Q000379:methods; D006801:Humans; D009062:Mouth Neoplasms / Q000235:genetics* / Q000378:metabolism*; D040901:Proteomics / Q000379:methods; D059467:Transcriptome / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor