title: Objective and quantitative assessment of motor function in Parkinson's disease-from the perspective of practical applications.
abstract: Parkinson's disease (PD) is a common neurodegenerative disorder with high morbidity because of the coming aged society. Currently, disease management and the development of new treatment strategies mainly depend on the clinical information derived from rating scales and patients' diaries, which have various limitations with regard to validity, inter-rater variability and continuous monitoring. Recently the prevalence of mobile medical equipment has made it possible to develop an objective, accurate, remote monitoring system for motor function assessment, playing an important role in disease diagnosis, home-monitoring, and severity evaluation. This review discusses the recent development in sensor technology, which may be a promising replacement of the current rating scales in the assessment of motor function of PD.
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Yang
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Wei-Xi
authors.initials: WX
authors.lastname: Xiong
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Feng-Tao
authors.initials: FT
authors.lastname: Liu
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Yi-Min
authors.initials: YM
authors.lastname: Sun
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Susan
authors.initials: S
authors.lastname: Luo
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Zheng-Tong
authors.initials: ZT
authors.lastname: Ding
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Wu
authors.affiliation: Department & Institute of Neurology, Huashan Hospital, Fudan University, Shanghai 200040, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Wang
keywords: Parkinson’s disease (PD); motor function; objective measurement; wearable sensors