title: Duchenne Muscular Dystrophy Mice and Men: Can Understanding a Genetic Cardiomyopathy Inform Treatment of Other Myocardial Diseases?
authors.affiliation: From the Department of Physiology and Cell Biology (J.A.R.-F., J.A.C.), Division of Cardiovascular Medicine, Department of Internal Medicine (S.V.R.), College of Medicine and Wexner Medical Center, The Ohio State University, Columbus. rafael-fortney.1@osu.edu.
authors.forename: Jill A
authors.initials: JA
authors.lastname: Rafael-Fortney
authors.affiliation: From the Department of Physiology and Cell Biology (J.A.R.-F., J.A.C.), Division of Cardiovascular Medicine, Department of Internal Medicine (S.V.R.), College of Medicine and Wexner Medical Center, The Ohio State University, Columbus.
authors.forename: Jessica A
authors.initials: JA
authors.lastname: Chadwick
authors.affiliation: From the Department of Physiology and Cell Biology (J.A.R.-F., J.A.C.), Division of Cardiovascular Medicine, Department of Internal Medicine (S.V.R.), College of Medicine and Wexner Medical Center, The Ohio State University, Columbus.
authors.forename: Subha V
authors.initials: SV
authors.lastname: Raman
mesh_terms: D000818:Animals; D009202:Cardiomyopathies / Q000628:therapy*; D002311:Cardiomyopathy, Dilated / Q000209:etiology* / Q000628:therapy; D002317:Cardiovascular Agents / Q000627:therapeutic use; D062507:Claudin-5 / Q000172:deficiency / Q000235:genetics; D018450:Disease Progression; D004311:Double-Blind Method; D004353:Drug Evaluation, Preclinical; D016189:Dystrophin / Q000172:deficiency / Q000235:genetics; D005786:Gene Expression Regulation; D015316:Genetic Therapy; D006333:Heart Failure / Q000188:drug therapy / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D051379:Mice; D018101:Mice, Inbred mdx; D000451:Mineralocorticoid Receptor Antagonists / Q000627:therapeutic use; D009137:Muscular Dystrophy, Animal / Q000150:complications / Q000235:genetics*; D020388:Muscular Dystrophy, Duchenne / Q000150:complications / Q000235:genetics*; D016032:Randomized Controlled Trials as Topic; D057170:Translational Research, Biomedical; D049411:Utrophin / Q000172:deficiency / Q000235:genetics
chemical_list: D002317:Cardiovascular Agents; D062507:Claudin-5; C491511:Cldn5 protein, mouse; C484258:DMD protein, human; D016189:Dystrophin; D000451:Mineralocorticoid Receptor Antagonists; C483600:Utrn protein, mouse; D049411:Utrophin
keywords: cardiomyopathy; claudin-5; dystrophin; heart; mineralocorticoid receptor