title: Optical coherence tomography angiography in paracentral acute middle maculopathy secondary to central retinal vein occlusion.
abstract: PurposeTo report the clinical course and the optical coherence tomography angiography (OCTA) findings of patients presenting with paracentral acute middle maculopathy (PAMM) and central retinal vein occlusion (CRVO).MethodsRetrospective case series. Clincal records and multimodal imaging findings of patients presenting with PAMM and CRVO were reviewed.ResultsThree eyes of three patients (2 males; mean age: 66 years) were included in the study. Mean follow-up was 9 months and images using OCTA (AngioVue OCT angiography system, Optovue, Inc., Fremont, CA, USA) were available at the last follow-up visit. During follow-up, best corrected visual acuity (BCVA) of case 1 was unchanged at 85 ETDRS letters and OCTA revealed a mild attenuation of the perifoveal deep capillary plexus (DCP); in case 2, BCVA changed from 83 to 77 ETDRS letters and OCTA revealed patchy areas of attenuation and pruning of the DCP; in case 3, BCVA decreased from 26 to 8 ETDRS letters and OCTA revealed extensive areas of DCP dropout.ConclusionThe natural course of visual acuity in patients with PAMM secondary to CRVO may vary. In these patients, the extent of DCP dropout on OCTA may reflect the extent of visual acuity impairment.
authors.affiliation: Ophthalmology Macular Service, Belfast Health and Social Care Trust and Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.|Department of Ophthalmology, Scientific Institute San Raffaele, Vita-Salute University, Milan, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Casalino
authors.affiliation: Ophthalmology Macular Service, Belfast Health and Social Care Trust and Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.
authors.forename: M
authors.initials: M
authors.lastname: Williams
authors.affiliation: Ophthalmology Macular Service, Belfast Health and Social Care Trust and Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.
authors.forename: C
authors.initials: C
authors.lastname: McAvoy
authors.affiliation: Department of Ophthalmology, Scientific Institute San Raffaele, Vita-Salute University, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Bandello
authors.affiliation: Ophthalmology Macular Service, Belfast Health and Social Care Trust and Centre for Experimental Medicine, Queen's University Belfast, Belfast, UK.
authors.forename: U
authors.initials: U
authors.lastname: Chakravarthy
mesh_terms: D000368:Aged; D000792:Angiography; D005260:Female; D006801:Humans; D007511:Ischemia / Q000000981:diagnostic imaging* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging; D012170:Retinal Vein Occlusion / Q000150:complications*; D012171:Retinal Vessels / Q000000981:diagnostic imaging* / Q000473:pathology; D012189:Retrospective Studies; D012607:Scotoma / Q000000981:diagnostic imaging* / Q000209:etiology; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology