title: Assessment of a Novel Anti-Aging Hand Cream.
abstract: There are few creams that have been developed for the purpose of treating the aging hand, yet UV damage and secondary signs of aging on the hands make them one of the most obvious indicators of age outside the face. This study documents results of a 120 day trial using a novel cream preparation containing ingredients including Retinol, Alpha-Arbutin, Kojic Dipalmitate, Azaeleic Acid, Hexylresorcinol, Licorice Root, and other ingredients. Results were tabulated comparing physician and patient assessment scores using a comprehensive scoring assay, which showed significant improvements across eight parameters tested. This was statistically significant for physician ratings of texture, wrinkles and pigment at 120 days versus baseline (P < 0.001). Further research is needed, but the results appear to indicate the benefits of a targeted hand cream in improving the appearance of the aging hand.
authors.forename: Joel
authors.initials: J
authors.lastname: Schlessinger
authors.forename: Subhash
authors.initials: S
authors.lastname: Saxena
authors.forename: Stuart
authors.initials: S
authors.lastname: Mohr
mesh_terms: D000328:Adult; D000368:Aged; D000975:Antioxidants / Q000008:administration & dosage; D005260:Female; D006225:Hand / Q000473:pathology*; D006801:Humans; D008875:Middle Aged; D017060:Patient Satisfaction; D010936:Plant Extracts / Q000008:administration & dosage; D011446:Prospective Studies; D015595:Skin Aging / Q000187:drug effects* / Q000473:pathology*; D063465:Skin Cream / Q000008:administration & dosage*; D014801:Vitamin A / Q000008:administration & dosage
chemical_list: D000975:Antioxidants; D010936:Plant Extracts; D014801:Vitamin A