title: Bottom-Up Fabrication of Nanopatterned Polymers on DNA Origami by In Situ Atom-Transfer Radical Polymerization.
abstract: Bottom-up strategies to fabricate patterned polymers at the nanoscale represent an emerging field in the development of advanced nanodevices, such as biosensors, nanofluidics, and nanophotonics. DNA origami techniques provide access to distinct architectures of various sizes and shapes and present manifold opportunities for functionalization at the nanoscale with the highest precision. Herein, we conduct in situ atom-transfer radical polymerization (ATRP) on DNA origami, yielding differently nanopatterned polymers of various heights. After cross-linking, the grafted polymeric nanostructures can even stably exist in solution without the DNA origami template. This straightforward approach allows for the fabrication of patterned polymers with low nanometer resolution, which provides access to unique DNA-based functional hybrid materials.
authors.affiliation: Organic Chemistry III, Macromolecular Chemistry and Biomaterials, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
authors.forename: Yu
authors.initials: Y
authors.lastname: Tokura
authors.affiliation: Organic Chemistry III, Macromolecular Chemistry and Biomaterials, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.|Centre for Advanced Macromolecular Design (CAMD), School of Chemistry, University of New South Wales, Sydney, NSW, 2052, Australia.
authors.forename: Yanyan
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: Preparative Macromolecular Chemistry, Institute for Technical Chemistry and Polymer Chemistry, Karlsruhe Institute of Technology (KIT), Engesserstrasse 18, 76131, Karlsruhe, Germany.|Institute for Biological Interfaces, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.|Karlsruhe Nano Micro Facility, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Welle
authors.affiliation: Centre for Advanced Macromolecular Design (CAMD), School of Chemistry, University of New South Wales, Sydney, NSW, 2052, Australia.
authors.forename: Martina H
authors.initials: MH
authors.lastname: Stenzel
authors.affiliation: Institute of Biophysics, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
authors.forename: Katarzyna M
authors.initials: KM
authors.lastname: Krzemien
authors.affiliation: Institute of Biophysics, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany.
authors.forename: Jens
authors.initials: J
authors.lastname: Michaelis
authors.affiliation: Max Planck Institute for Polymer Research, Ackermannweg 10, 55128, Mainz, Germany.
authors.forename: Rüdiger
authors.initials: R
authors.lastname: Berger
authors.affiliation: Preparative Macromolecular Chemistry, Institute for Technical Chemistry and Polymer Chemistry, Karlsruhe Institute of Technology (KIT), Engesserstrasse 18, 76131, Karlsruhe, Germany.|Institute for Biological Interfaces, Karlsruhe Institute of Technology (KIT), Hermann-von-Helmholtz-Platz 1, 76344, Eggenstein-Leopoldshafen, Germany.
authors.forename: Christopher
authors.initials: C
authors.lastname: Barner-Kowollik
authors.affiliation: Organic Chemistry III, Macromolecular Chemistry and Biomaterials, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany. yuzhou.wu@uni-ulm.de.
authors.forename: Yuzhou
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Organic Chemistry III, Macromolecular Chemistry and Biomaterials, Ulm University, Albert-Einstein-Allee 11, 89081, Ulm, Germany. tanja.weil@uni-ulm.de.
authors.forename: Tanja
authors.initials: T
authors.lastname: Weil
keywords: DNA nanotechnology; atom-transfer radical polymerization; origami nanostructures; polymerization; self-assembly