title: Changes in self-reported health and quality of life in octogenarian patients one month after transcatheter aortic valve implantation.
abstract: In addition to favourable results regarding mortality and morbidity it is important to identify the impact transcatheter aortic valve implantation (TAVI) has on patients' quality of life.
  
  
  
  The aims were: (i) to describe clinical characteristics, self-reported health and quality of life in octogenarians before TAVI intervention; (ii) to determine changes in self-reported health and quality of life one month after TAVI; and (iii) to establish the clinical importance of the findings.
  
  
  
  A prospective cohort study was conducted on consecutively enrolled octogenarians with severe aortic stenosis undergoing TAVI ( N = 65). Self-reported health and quality of life were recorded at baseline and one month later using two global questions from the World Health Organization Quality of Life Instrument Abbreviated (WHOQOL-BREF), the generic Short Form Health 12 and the disease-specific Minnesota Living with Heart Failure Questionnaire.
  
  
  
  One month after TAVI, WHOQOL-BREF showed that self-reported health improved moderately ( p < 0.001), while quality of life improved slightly, but not statistically significantly ( p = 0.06). There were changes in all Short Form Health 12 domains, except social functioning and role emotional. The estimated changes were 3.6 to 5.8 with large confidence intervals. The Physical Component Summary increased statistically significantly from baseline to 30 days (30.6-34.7; p = 0.02), but the Mental Component Summary did not (46.9-50.0; p = 0.13).
  
  
  
  Despite being an advanced treatment performed in a high risk population, TAVI in octogenarians improves short-term self-reported global health and generic physical health and quality of life. These patient-reported outcomes have importance, particularly in this age group.
authors.affiliation: 1 Division of Internal Medicine, University Hospital of North Norway, Harstad, Norway.|2 Department of Health and Care Sciences, The Arctic University of Norway, Harstad, Norway.
authors.forename: Siv Js
authors.initials: SJ
authors.lastname: Olsen
authors.affiliation: 3 Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.|4 School for Health and Welfare, Jönköping University, Sweden.|5 Institute of Nursing, Faculty of Health and Social Science, Bergen University College, Norway.
authors.forename: Bengt
authors.initials: B
authors.lastname: Fridlund
authors.affiliation: 6 Department of Clinical Science, University of Bergen, Norway.
authors.forename: Leslie Sp
authors.initials: LS
authors.lastname: Eide
authors.affiliation: 7 Centre for Clinical Research, Haukeland University Hospital, Bergen, Norway.
authors.forename: Karl O
authors.initials: KO
authors.lastname: Hufthammer
authors.affiliation: 3 Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.
authors.forename: Karel Kj
authors.initials: KK
authors.lastname: Kuiper
authors.affiliation: 6 Department of Clinical Science, University of Bergen, Norway.|8 Department of Cardiology, Stavanger University Hospital, Norway.
authors.forename: Jan E
authors.initials: JE
authors.lastname: Nordrehaug
authors.affiliation: 3 Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.|9 Kavli Research Centre for Geriatrics and Dementia, Haraldsplass Deaconess Hospital, Bergen, Norway.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Skaar
authors.affiliation: 3 Department of Heart Disease, Haukeland University Hospital, Bergen, Norway.|5 Institute of Nursing, Faculty of Health and Social Science, Bergen University College, Norway.|6 Department of Clinical Science, University of Bergen, Norway.
authors.forename: Tone M
authors.initials: TM
authors.lastname: Norekvål
mesh_terms: D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000601:surgery*; D015331:Cohort Studies; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D057566:Self Report; D011795:Surveys and Questionnaires; D013997:Time Factors; D065467:Transcatheter Aortic Valve Replacement / Q000523:psychology*
keywords: TAVI; older people; quality of life; self-reported health; severe aortic stenosis