title: Comparing long-term outcomes between early and delayed initiation of peritoneal dialysis following catheter implantation.
abstract: OBJECTIVE
  The aim of this study was to compare peritonitis rates, peritoneal dialysis technique survival and patient survival between patients who started peritoneal dialysis earlier than 14 days (early starters) and 14 days or more (delayed starters) after insertion of a Tenckhoff catheter.
  
  
  METHODS
  Observational analysis was performed for all patients who underwent insertion of a Tenckhoff catheter at Far Eastern Memorial Hospital between 1 January 2006 and 31 December 2012. The patients were divided into two groups: early and delayed starters. The rate and outcomes of peritonitis were recorded. Peritoneal dialysis technique survival and patient survival were analyzed using the Kaplan-Meier method. Cox regression analysis was performed for peritoneal dialysis technique failure and patient mortality.
  
  
  RESULTS
  There were 80 early starters and 69 delayed starters. The peritonitis rate was 0.18 episodes per year in early starters and 0.13 episodes per year in delayed starters. There was no significant difference of peritonitis free survival (p = 0.146), peritoneal dialysis technique survival (p = 0.273) and patient survival (p = 0.739) at 1, 3, 5 years between early starters and delayed starters. After adjustment with age, albumin and diabetes, early starters did not have an increased risk of peritonitis, technique failure and mortality compared to delayed starters.
  
  
  CONCLUSIONS
  Compared to the patients who started peritoneal dialysis 14 days or more after catheter implantation, the patients who started earlier did not have an increased risk of peritonitis, peritoneal dialysis technique failure and mortality.
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Mei-Fen
authors.initials: MF
authors.lastname: Pai
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Ju-Yeh
authors.initials: JY
authors.lastname: Yang
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Hung-Yuan
authors.initials: HY
authors.lastname: Chen
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Shih-Ping
authors.initials: SP
authors.lastname: Hsu
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Yen-Ling
authors.initials: YL
authors.lastname: Chiu
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Hon-Yen
authors.initials: HY
authors.lastname: Wu
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Wan-Chuan
authors.initials: WC
authors.lastname: Tsai
authors.affiliation: a Division of Nephrology, Department of Internal Medicine , Far Eastern Memorial Hospital , New Taipei City , Taiwan , R.O.C.
authors.forename: Yu-Seng
authors.initials: YS
authors.lastname: Peng
mesh_terms: D000328:Adult; D000368:Aged; D002404:Catheterization; D003404:Creatinine / Q000097:blood*; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D053208:Kaplan-Meier Estimate; D007676:Kidney Failure, Chronic / Q000401:mortality* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D010531:Peritoneal Dialysis, Continuous Ambulatory / Q000379:methods*; D010538:Peritonitis / Q000453:epidemiology*; D016016:Proportional Hazards Models; D012189:Retrospective Studies; D013624:Taiwan; D016896:Treatment Outcome
chemical_list: D003404:Creatinine
keywords: Catheter-related infections; peritoneal dialysis; peritonitis; renal dialysis; survival