title: [EFFECT OF ANTIOXIDANTS ON ESOPHAGUS TISSUE REPAIR UPON EXPERIMENTAL CHEMICAL BURN FROM ACETIC ACID].
abstract: This work is an experimental study on 30 rabbits to determine the effect of antioxidants on the process of repair of the esophagus. Chemical agent was 46% acetic acid, a The antioxidant "Mexidol" were injected to core group of test animals in 2 weeks. Animals were taken from the experiment at 5, 14, 21, 30, 45 and 60 hours. We conducted morphometric study of histological exemplars, determining the number of inflammatory cells, epithelial thickness, the area of newformed blood vessels. In the study group we reported an improvement of reparative processes in the wall of the body: it was increased blood supply to the burn surface on 242% and more rapid relief of inflammatory processes on 117% (p < 0.05).
authors.forename: A V
authors.initials: AV
authors.lastname: Klimashevich
authors.forename: V I
authors.initials: VI
authors.lastname: Nikol'skii
authors.forename: A V
authors.initials: AV
authors.lastname: Shabrov
mesh_terms: D019342:Acetic Acid; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D002057:Burns, Chemical / Q000188:drug therapy* / Q000473:pathology; D004848:Epithelium / Q000187:drug effects / Q000293:injuries; D004947:Esophagus / Q000098:blood supply / Q000187:drug effects* / Q000293:injuries; D007273:Injections, Intramuscular; D008297:Male; D018919:Neovascularization, Physiologic / Q000187:drug effects; D010847:Picolines / Q000494:pharmacology*; D011817:Rabbits; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D000975:Antioxidants; D010847:Picolines; C070020:emoxypine succinate; D019342:Acetic Acid