title: Human Beige Adipocytes: Epiphenomenon or Drivers of Metabolic Improvements?
abstract: There is a lack of direct evidence that human brown or beige adipocytes improve whole-body energy homeostasis. In a recent study, Min et al. implanted proliferated human adipocyte progenitors from a 3D culture system in mice. Implants responded to adipogenic stimuli and had a beige-like phenotype upon induction that significantly improved systemic metabolic parameters.
authors.affiliation: Touchstone Diabetes Center, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
authors.forename: Qiong A
authors.initials: QA
authors.lastname: Wang
authors.affiliation: Touchstone Diabetes Center, Department of Internal Medicine, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: Philipp.Scherer@utsouthwestern.edu.
authors.forename: Philipp E
authors.initials: PE
authors.lastname: Scherer
mesh_terms: D000069797:Adipocytes, Beige / Q000166:cytology* / Q000378:metabolism*; D052437:Adipocytes, Brown / Q000166:cytology / Q000378:metabolism; D050156:Adipogenesis / Q000235:genetics / Q000502:physiology; D000818:Animals; D018929:Cell Culture Techniques; D006801:Humans; D051379:Mice; D022722:Thermogenesis / Q000235:genetics / Q000502:physiology