title: Chemical composition of groundwater/drinking water and oncological disease mortality in Slovak Republic.
abstract: This study deals with the analysis of relationship between chemical composition of the groundwater/drinking water and the data on mortality from oncological diseases (MOD) in the Slovak Republic. Primary data consist of the Slovak national database of groundwater analyses (20,339 chemical analyses, 34 chemical elements/compounds) and data on MOD (17 health indicators) collected for the 10-year period (1994-2003). The chemical and health data were unified in the same form and expressed as the mean values for each of 2883 municipalities within the Slovak Republic. Pearson and Spearman correlation as well as artificial neural network (ANN) methods were used for analysis of the relationship between chemical composition of groundwater/drinking water and MOD. The most significant chemical elements having influence on MOD were identified together with their limit values (limit and optimal contents). Based on the results of calculations, made through the neural networks, the following eight chemical elements/parameters in the groundwater were defined as the most significant for MOD: Ca + Mg (mmol l-1), Ca, Mg, TDS, Cl, HCO3, SO4and NO3. The results document the highest relationship between MOD and groundwater contents of Ca + Mg (mmol l-1), Ca and Mg. We observe increased MOD with low (deficit) contents of these three parameters of groundwater/drinking water. The following limit values were set for the most significant groundwater chemicals/parameters: Ca + Mg 1.73-5.85 mmol l-1, Ca 60.5-196.8 mg l-1and Mg 25.6-35.8 mg l-1. At these concentration ranges, the mortality for oncological diseases in the Slovak Republic is at the lowest levels. These limit values are about twice higher in comparison with the current Slovak valid guideline values for the drinking water.
authors.affiliation: State Geological Institute of Dionyz Stur, Mlynská dolina 1, 817 04, Bratislava, Slovak Republic. stanislav.rapant@geology.sk.|Faculty of Tourism, Goethe Uni Bratislava, Winterová 29, 921 01, Piešťany, Slovak Republic. stanislav.rapant@geology.sk.
authors.forename: S
authors.initials: S
authors.lastname: Rapant
authors.affiliation: State Geological Institute of Dionyz Stur, Mlynská dolina 1, 817 04, Bratislava, Slovak Republic.
authors.forename: V
authors.initials: V
authors.lastname: Cvečková
authors.affiliation: State Geological Institute of Dionyz Stur, Mlynská dolina 1, 817 04, Bratislava, Slovak Republic.
authors.forename: K
authors.initials: K
authors.lastname: Fajčíková
authors.affiliation: Regional Public Health Authority of the Slovak Republic, Ipeľská 1, 040 11, Kosice, Slovak Republic.
authors.forename: Z
authors.initials: Z
authors.lastname: Dietzová
authors.affiliation: Faculty of Economy and Business, Panaeuropean University, Tematínska 10, 851 05, Bratislava, Slovak Republic.
authors.forename: B
authors.initials: B
authors.lastname: Stehlíková
mesh_terms: D060766:Drinking Water / Q000737:chemistry*; D060587:Groundwater / Q000737:chemistry*; D006801:Humans; D009369:Neoplasms / Q000139:chemically induced / Q000401:mortality*; D018154:Slovakia / Q000453:epidemiology
chemical_list: D060766:Drinking Water
keywords: Calcium; Groundwater; Magnesium; Neural network; Oncological mortality; Slovak Republic