title: NUTRITIONAL THERAPY IN THE TREATMENT OF ACUTE CORROSIVE INTOXICATION IN ADULTS.
abstract: BACKGROUND
  Acute intoxications with corrosive substances can cause severe chemical injuries of the upper gastrointestinal tract, most often located in the mouth, pharynx, esophagus, stomach and duodenum. If a patient survives the acute phase of intoxication, regenerative response may result in esophageal and/or gastric stenosis, and increased risk of esophageal and gastric cancer. Such intoxication may be fatal due to perforation or tracheal necrosis. Enteral nutrition is a nutritional method when nutritional substances are administered through specially designed tubing placed through the nose or percutaneously, directly into the GIT.
  
  
  OBJECTIVE
  The aim of this study is to describe the methods of artificial nutrition in patients with acute corrosive intoxications and the importance of nutritional support in the treatment of these intoxications.
  
  
  CONCLUSIONS
  Nutrition in the treatment of acute corrosive intoxications is one of the most important therapeutic processes that largely contribute to faster recovery of the post-corrosive injuries of upper GIT, stabilization of biologic, immunologic and metabolic parameters, and reduction of length of stay in hospital Aim of the treatment of acute corrosive intoxications is to prevent perforation and progressive fibrosis, and esophageal and gastric stenosis. There are different and often conflicting positions, on the conservative treatment of acute corrosive intoxications in adults. Such treatment mainly consists of anti-secretory treatment, antibiotics and intensive hyper-alimentation, aiming to prevent late post-corrosive intoxications.
  
  
  CONCLUSIONS
  It is considered that nutritional support plays a major role in maintenance of metabolic processes and prevention of severe metabolic complications that could additionally aggravate the condition and impair the treatment.
authors.affiliation: University Clinic for Toxicology and Urgent Internal Medicine, Skopje, Republic of Macedonia.
authors.forename: Andon
authors.initials: A
authors.lastname: Chibishev
authors.affiliation: University "Goce Delcev", Medical faculty, Shtip, Republic of Macedonia.
authors.forename: Velo
authors.initials: V
authors.lastname: Markoski
authors.affiliation: University Clinic for Toxicology and Urgent Internal Medicine, Skopje, Republic of Macedonia.
authors.forename: Ivica
authors.initials: I
authors.lastname: Smokovski
authors.affiliation: Institute for Preclinical Pharmacology and Toxicology, Skopje, Republic of Macedonia.
authors.forename: Emilija
authors.initials: E
authors.lastname: Shikole
authors.affiliation: University Clinic for Toxicology and Urgent Internal Medicine, Skopje, Republic of Macedonia.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Stevcevska
keywords: corrosive poisonings; deglutition; deglutition disorders; enteral nutrition; nutritional therapy; parenteral nutrition