title: For an alliance between science, ethics and politics in promoting paediatric trials. Commentary.
abstract: After several decades during which children tended to be excluded from clinical trials, provisions to encourage trials with children have been in place for some years both at international level and in individual countries. The Nuffield Council on Bioethics has published a broad-ranging report on the subject, which makes concrete proposals for decision-makers and comes at a crucial moment in the definition of European Union regulations on this topic.
authors.affiliation: Unità di Bioetica, Presidenza, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Petrini
authors.affiliation: UO Malattie Rare, Dipartimento Medicina Pediatrica, Ospedale Bambino Gesù, Rome, Italy.
authors.forename: Ippolita
authors.initials: I
authors.lastname: Rana
authors.affiliation: Dipartimento di Biologia Cellulare e Neuroscienze, Istituto Superiore di Sanità, Rome, Italy.
authors.forename: Enrico
authors.initials: E
authors.lastname: Alleva
mesh_terms: D000328:Adult; D002648:Child; D002986:Clinical Trials as Topic / Q000331:legislation & jurisprudence; D004992:Ethics, Medical; D005062:European Union; D006801:Humans; D010372:Pediatrics / Q000331:legislation & jurisprudence / Q000458:organization & administration*; D011057:Politics; D012586:Science / Q000941:ethics*