title: Intramolecular addition of diarylmethanols to imines promoted by KOt-Bu/DMF: a new synthetic approach to indole derivatives.
abstract: KOt-Bu/DMF promoted intramolecular addition of diarylmethanols to imines was developed. A series of 2,3-disubstituted indoles was obtained in good yields. A reaction mechanism of radical cyclization and subsequent dehydration is proposed.
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Jia-Hua
authors.initials: JH
authors.lastname: Chen
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Zi-Cong
authors.initials: ZC
authors.lastname: Chen
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Hong
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Wei-Juan
authors.initials: WJ
authors.lastname: Wang
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Zou
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Xue-Jing
authors.initials: XJ
authors.lastname: Zhang
authors.affiliation: Institute of Drug Synthesis and Pharmaceutical Process, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. zhangxj33@mail.sysu.edu.cn.
authors.forename: Ming
authors.initials: M
authors.lastname: Yan