title: [THE MOLECULAR GENETIC CHARACTERISTIC OF SPECIES CONTENT OF SALIVA AND GINGIVAL RECESS UNDER PERIODONTITIS].
abstract: The examination was carried out of samplings of 110 patients with periodontitis (observation group) and 60 patients without pathology of periodont (comparison group). The polymerase chain reaction was used to analyze samples of saliva and contents of periodontal recesses for detecting species-specific DNA fragments of Porphymmonas gigngivalis, Streptococcus macacae, S. mutans, S. oralis, S. salivarius, S. sangis, S. sobrinus, Treponema denticola. In patients with periodontitis S. mutans, S. oralis S. sobrinus were reliably more often detected in the content of periodontal recesses and S. mutans, S. sobrinus i in saliva. In the observation group the rate of detection of association S. mutans--S. oralis--S. sangis--S. sobrinus was significantly exceeded (up to 15.6%, X2 = 9.1, p = 0.004). In ten days of effective treatment of periodontitis reliable decreastng of rate of detection of S. wasoralis, S. sobrinus was observed in contents of periodontal recesses but not in of saliva. The detection of S.sobrinus using technique of polymerase chain reaction in contents of periodontal recesses and/or saliva of patients with periodontitis has a diagnostic value. The detection of S.sobrinus in contents of periodontal recesses is significant both in monoculture and in association S. mutans--S. oralis--S. sangis--S.sobrinus. The absence of S. sobrinus in contents of periodontal recesses testifies effectiveness of treatment of main disease (periodontitis).
authors.forename: E R
authors.initials: ER
authors.lastname: Tamarova
authors.forename: A Kh
authors.initials: AKh
authors.lastname: Baimiev
authors.forename: K Yu
authors.initials: KY
authors.lastname: Shvetz
authors.forename: A R
authors.initials: AR
authors.lastname: Mavzyutov
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D004269:DNA, Bacterial / Q000235:genetics*; D005260:Female; D005881:Gingiva / Q000382:microbiology; D006801:Humans; D008012:Lidocaine; D008034:Lincomycin / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D010514:Periodontal Pocket / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D010518:Periodontitis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology / Q000473:pathology; D016133:Polymerase Chain Reaction / Q000379:methods; D016966:Porphyromonas gingivalis / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D012463:Saliva / Q000382:microbiology; D013291:Streptococcus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D048373:Treponema denticola / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification
chemical_list: D000779:Anesthetics, Local; D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial; D008012:Lidocaine; D008034:Lincomycin