title: Vascular Regression After Pinguecula Excision and Conjunctival Autograft Using Fibrin Glue.
abstract: OBJECTIVE
  To determine the change in local vascularization after pinguecula excision and conjunctival autograft secured with fibrin glue at 12 months.
  
  
  METHODS
  Thirty-one eyes of 31 patients which underwent excision and conjunctival autografting with fibrin glue were retrospectively reviewed. Anterior segment photography was obtained before and after the surgery. Cosmetic outcome was evaluated by patient self-grading (five-point scale; excellent (5), good (4), acceptable (3), poor (2), and very poor (1)), and medical evaluation of treatment outcome was based on subjective evaluation of vascularization on anterior segment photography (four-point severity scale; 0 [low] to 3 [high]). Clinical outcome and complications are reported at 12 months.
  
  
  RESULTS
  Overall cosmetic results were excellent or good in 93.5% (29 of 31) (score 4.68±0.60). Anterior segment photography showed that most cases demonstrated complete removal of pinguecula and regression of surrounding vascularization with mean change in score from 2.13±0.34 preoperatively to 0.09±0.30 postoperatively.
  
  
  CONCLUSIONS
  Pinguecula excision and conjunctival autograft using fibrin glue is an effective and safe method to remove pinguecula for cosmetic purposes. The method presented facilitated regression of vascularization.
authors.affiliation: Department of Ophthalmology (S.J., J.-W.K.), Myongji Hospital Seonam University College of Medicine, Goyang, Korea; Department of Ophthalmology (H.S.H.), Chuncheon Sacred Heart Hospital Hallym University College of Medicine, Chuncheon, Korea; and Department of Ophthalmology and Visual Sciences (R.S.C., J.-W.K.), Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY.
authors.forename: Seungil
authors.initials: S
authors.lastname: Jung
authors.forename: Ji-Won
authors.initials: JW
authors.lastname: Kwon
authors.forename: Ho Sik
authors.initials: HS
authors.lastname: Hwang
authors.forename: Roy S
authors.initials: RS
authors.lastname: Chuck
mesh_terms: D000328:Adult; D000869:Anterior Eye Segment / Q000473:pathology; D064592:Autografts; D003228:Conjunctiva / Q000098:blood supply / Q000637:transplantation*; D003229:Conjunctival Diseases / Q000175:diagnosis / Q000601:surgery*; D018450:Disease Progression; D005260:Female; D015718:Fibrin Tissue Adhesive / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000473:pathology; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D011183:Postoperative Complications / Q000473:pathology / Q000517:prevention & control*; D012189:Retrospective Studies; D014014:Tissue Adhesives / Q000627:therapeutic use; D016378:Tissue Transplantation / Q000379:methods*; D055815:Young Adult
chemical_list: D015718:Fibrin Tissue Adhesive; D014014:Tissue Adhesives