title: Personalized external aortic root support: a review of the current status.
abstract: Personalized external aortic root support (PEARS) is an emerging technology. It is a pre-emptive operation to halt aortic root expansion and maintain aortic valve function in Marfan syndrome and is also applicable to aortic root aneurysms of other aetiologies. To fully evaluate PEARS, awareness of all those who advise these patients is necessary to ensure that patients are fully informed of the alternative operations, to carefully build experience, to ensure safety and quality and to monitor outcomes. Herein, we present a summary of published methods and outcomes and the arrangements in place for fuller evaluation.
authors.affiliation: Clinical Operational Research Unit, University College London, London, UK tom.treasure@gmail.com.
authors.forename: Tom
authors.initials: T
authors.lastname: Treasure
authors.affiliation: John Radcliffe Hospital, Oxford, UK.
authors.forename: Mario
authors.initials: M
authors.lastname: Petrou
authors.affiliation: NIHR Biomedical Research Unit, Royal Brompton Hospital, London, UK.
authors.forename: Ulrich
authors.initials: U
authors.lastname: Rosendahl
authors.affiliation: St Thomas' Hospital, London, UK.
authors.forename: Conal
authors.initials: C
authors.lastname: Austin
authors.affiliation: Leuven University Hospital, Leuven, Belgium.
authors.forename: Filip
authors.initials: F
authors.lastname: Rega
authors.affiliation: Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
authors.forename: Jan
authors.initials: J
authors.lastname: Pirk
authors.affiliation: NIHR Biomedical Research Unit, Royal Brompton Hospital, London, UK.
authors.forename: John
authors.initials: J
authors.lastname: Pepper
mesh_terms: D001011:Aorta / Q000601:surgery*; D001014:Aortic Aneurysm / Q000601:surgery*; D001807:Blood Vessel Prosthesis / Q000009:adverse effects; D017076:Computer-Aided Design; D006801:Humans; D008382:Marfan Syndrome / Q000601:surgery*; D011474:Prosthesis Design; D013526:Surgical Mesh; D013673:Technology Assessment, Biomedical
keywords: Aortic root aneurysm; Marfan syndrome; Personalized external aortic root support