title: Comparison of laparoscopy and open surgery in treating severe acute pancreatitis and its relative aftercare.
abstract: This study was designed to determine the effects and compare laparoscopic intervention and open surgery in treating severe acute pancreatitis (SAP) and its relative aftercare, to improve the overall treatment of SAP. Ninety patients with SAP were enrolled from the 2nd Affiliated Hospital of Harbin Medical University from 2008 to 2014 and divided into a laparoscopic intervention group (25 cases) and an open surgery group (65 cases). Patients were asked for clinical symptoms, general hospital information, laboratory inspection, imageological examination, local and systemic complications, treatment and outcome. SAP patients relevant clinical indicators were compared between the two groups before and after the operation. Results revealed that there was no statistical significance in lesion range and main scoring indexes for reflecting the severity of the disease. For both groups statistical significance was found in blood loss (285.3±79.8 mL vs 362±91.6 mL), intensive care unit (ICU) monitoring time (9.04±6.35 d vs 12.48±8.34 d) and service time of breathing machine (9.47±6.24 d vs 12.98±8.25 d), and the laparoscopic operation group was superior to the open surgery group (p < 0.05). Besides, the laparoscopic operation group was also superior to the open surgery group in demand for main analgesics one week after the operation, as well as for recovery rate and incidence of complications (p < 0.05). Thus, it can be concluded that patients undergoing laparoscopic intervention are less likely to develop pulmonary infection and more likely to be cured in comparison with patients who receive open surgery. In addition, laparoscopic intervention results in less damage, lighter pain and fewer complications compared with open surgery.
authors.affiliation: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Radiotherapy, Harbin Medical University Cancer Hospital, Harbin, China.
authors.forename: M X
authors.initials: MX
authors.lastname: Jiang
authors.affiliation: Department of Ear-Nose-Throat, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: Department of Orthopaedics, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: M
authors.initials: M
authors.lastname: Shu
authors.affiliation: Department of General Surgery, The 2nd Affiliated Hospital of Harbin Medical University, Harbin, China.
authors.forename: S B
authors.initials: SB
authors.lastname: Sun
mesh_terms: D000208:Acute Disease; D000328:Adult; D000359:Aftercare; D000368:Aged; D000681:Amylases / Q000097:blood; D000700:Analgesics / Q000627:therapeutic use; D002118:Calcium / Q000097:blood; D005260:Female; D006801:Humans; D007362:Intensive Care Units; D010535:Laparoscopy / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000097:blood / Q000188:drug therapy / Q000201:enzymology / Q000601:surgery*; D011182:Postoperative Care; D011183:Postoperative Complications / Q000209:etiology; D012121:Respiration, Artificial; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000700:Analgesics; D000681:Amylases; D002118:Calcium