title: Evaluation of RGP Contact Lens Fitting in Keratoconus Patients Using Hierarchical Fuzzy Model and Genetic Algorithms.
abstract: Keratoconus is a progressive non-inflammatory disease of the cornea. Rigid gas permeable contact lenses (RGPs) are prescribed when the disease progresses. Contact lens fitting and assessment is very difficult in these patients and is a concern of ophthalmologists and optometrists. In this study, a hierarchical fuzzy system is used to capture the expertise of experienced ophthalmologists during the lens evaluation phase of prescription. The system is fine-tuned using genetic algorithms. Sensitivity, specificity and accuracy of the final system are 88.9%, 94.4% and 92.6% respectively.
authors.affiliation: Medical Informatics Department, School of Allied Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Falahati Marvast
authors.affiliation: Research Centre for Biomedical Technology and Robotics (RCBTR), Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Arabalibeik
authors.affiliation: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Alipour
authors.affiliation: Health Information Management Department, School of Health Management and Information Science, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Sheikhtaheri
authors.affiliation: Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Leila
authors.initials: L
authors.lastname: Nouri
authors.affiliation: Research Centre for Biomedical Technology and Robotics (RCBTR), Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Soozande
authors.affiliation: Research Centre for Biomedical Technology and Robotics (RCBTR), Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Masood
authors.initials: M
authors.lastname: Yarmahmoodi
mesh_terms: D000465:Algorithms; D003261:Contact Lenses; D020000:Decision Support Systems, Clinical / Q000458:organization & administration*; D017143:Fuzzy Logic; D006801:Humans; D007640:Keratoconus / Q000175:diagnosis / Q000534:rehabilitation*; D000069550:Machine Learning; D008957:Models, Genetic; D017755:Prosthesis Fitting / Q000379:methods*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013813:Therapy, Computer-Assisted / Q000379:methods*; D016896:Treatment Outcome