title: Commentary on "Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives".
abstract: We comment on the recent report entitled "Platelet Studies in Autism Spectrum Disorder Patients and First-Degree Relatives" [Molecular Autism 2015;6:57]. We find it commendable that the authors have investigated platelet factors potentially involved in the well-replicated observation of platelet hyperserotonemia in autism. However, we believe the results need a fuller discussion in the context of prior studies, think that certain aspects of the interpretation need to be reassessed, and attempt to provide a framework for further research in this area.
authors.affiliation: Yale Child Study Center, Yale University School of Medicine, 230 South Frontage Rd., 06519 New Haven, CT USA ; Department of Laboratory Medicine, Yale University School of Medicine, New Haven, CT USA.
authors.forename: George M
authors.initials: GM
authors.lastname: Anderson
authors.affiliation: Institute for Juvenile Research, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL USA.
authors.forename: Edwin H
authors.initials: EH
authors.lastname: Cook
keywords: 5-HT; Autism; Hyperserotonemia; Platelet aggregation; Platelet count; Platelet functioning; Platelet release; Serotonin