title: RETRACTED: miR-221/222 enhance the tumorigenicity of human breast cancer stem cells via modulation of PTEN/Akt pathway.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the Editor-in-Chief.
  
  Concerns were raised in the public domain and also reported by the authors to the journal regarding the similarity between various panels from Figures 2 and 3. Given also the institutional investigation, the journal requested the authors to provide the raw data. However, the authors were not able to provide raw data of sufficient quality and detail for the journal to independently audit the provenance and validity of the data, and therefore the Editor-in-Chief decided to retract the article.
authors.affiliation: Department of Clinical Medicine, Grade 2013, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Bailong
authors.initials: B
authors.lastname: Li
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Lu
authors.affiliation: Academic Affairs Department, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Honghai
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Xiaocui
authors.initials: X
authors.lastname: Han
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Mao
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Jiazhi
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Lihui
authors.initials: L
authors.lastname: Yu
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Shujun
authors.initials: S
authors.lastname: Fan
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China.
authors.forename: Xiaotang
authors.initials: X
authors.lastname: Yu
authors.affiliation: Department of Pathology and Forensics, Dalian Medical University, No. 9 West Section, Lvshun Road, Dalian 116044, China. Electronic address: yr0806@hotmail.com.
authors.forename: Bo
authors.initials: B
authors.lastname: Song
mesh_terms: D001483:Base Sequence; D001943:Breast Neoplasms / Q000235:genetics / Q000473:pathology*; D063646:Carcinogenesis / Q000235:genetics* / Q000473:pathology; D002465:Cell Movement; D049109:Cell Proliferation; D004789:Enzyme Activation; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D061986:MCF-7 Cells; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism*; D009361:Neoplasm Invasiveness; D014411:Neoplastic Stem Cells / Q000378:metabolism / Q000473:pathology*; D051059:PTEN Phosphohydrolase / Q000378:metabolism*; D051057:Proto-Oncogene Proteins c-akt / Q000378:metabolism*; D015398:Signal Transduction / Q000235:genetics; D018874:Spheroids, Cellular / Q000378:metabolism / Q000473:pathology
chemical_list: D035683:MicroRNAs; D051059:PTEN Phosphohydrolase; D051057:Proto-Oncogene Proteins c-akt; C525709:MIR221, human; C525710:MIR222, human; C494929:PTEN protein, human
keywords: Breast cancer; Cancer stem cell; PTEN/Akt pathway; microRNA-221/222