title: Lymphangioma Circumscriptum: Good Clinical Response to Isotretinoin Therapy.
abstract: Lymphangioma circumscriptum (LC) is a superficial form of lymphatic malformation that can be difficult to treat. Therapeutic approaches to LC such as laser therapy, sclerotherapy, and surgical excision give varying results. This is the first description of a case of LC successfully treated with oral isotretinoin. Further studies are needed to confirm whether this is a reproducible treatment option.
authors.affiliation: Department of Dermatology, Tokat Zile State Hospital, Tokat, Turkey.
authors.forename: Erhan
authors.initials: E
authors.lastname: Ayhan
mesh_terms: D000284:Administration, Oral; D000293:Adolescent; D001707:Biopsy, Needle; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007150:Immunohistochemistry; D015474:Isotretinoin / Q000627:therapeutic use*; D007641:Keratolytic Agents / Q000627:therapeutic use*; D008202:Lymphangioma / Q000175:diagnosis* / Q000188:drug therapy*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000188:drug therapy*; D013848:Thigh; D016896:Treatment Outcome
chemical_list: D007641:Keratolytic Agents; D015474:Isotretinoin