title: Orofacial Pain: Pharmacologic Paradigms for Therapeutic Intervention.
abstract: Pain is a universal experience with profound effects on the physiology, psychology, and sociology of the population. Orofacial pain (OFP) conditions are especially prevalent and can be severely debilitating to a patient's health-related quality of life. Evidence-based clinical trials suggest that pharmacologic therapy may significantly improve patient outcomes either alone or when used as part of a comprehensive treatment plan for OFP. The aim of this article is to provide therapeutic options from a pharmacologic perspective to treat a broad spectrum of OFP. Clinical-based systemic and topical applied pharmaceutical approaches are presented to treat the most common OFP syndromes.
authors.affiliation: Residency, Oral and Maxillofacial Surgery, Meharry Medical College, 1005 TB Todd Jr. Boulevard, Nashville, TN 37208, USA. Electronic address: lhalpern@mmc.edu.
authors.forename: Leslie
authors.initials: L
authors.lastname: Halpern
authors.affiliation: Oral and Maxillofacial Surgery, Meharry Medical College, 1005 TB Todd Jr. Boulevard, Nashville, TN 37208, USA.
authors.forename: Porchia
authors.initials: P
authors.lastname: Willis
mesh_terms: D005157:Facial Pain / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D015995:Prevalence; D011788:Quality of Life
keywords: Anticonvulsants; Antidepressants; Antivirals; Botox; Episodic/continuous pain; SSRIs; Topical medicaments