title: [Current status of urinary iodine analysis and its clinical interest].
abstract: Iodine deficiency especially during pregnancy causes neurological disorders in the fetus. Actually, about two billion people are suffering from iodine deficiency through the world. The assessment of iodine intake is based on the determination of urinary iodine in the target population. Despite the complexity of the urinary matrix, a reliable assay must be achieved. After a review of pathophysiological interest of urinary iodine, various techniques for its measurement and their analytical performance were analyzed in order to select a reliable technique and enhance results interpretation.
authors.affiliation: Laboratoire de surveillance et d'épidémiologie nutritionnelles en Tunisie, Institut national de nutrition et de technologie alimentaire, Bab Saadoun-Tunis, Tunisie.
authors.forename: Radhouene
authors.initials: R
authors.lastname: Doggui
authors.affiliation: Laboratoire de toxicologie, Unité de toxicologie, recherche et environnement, Montfleury, Tunis, Tunisie.
authors.forename: Myriam
authors.initials: M
authors.lastname: El Ati-Hellal
authors.affiliation: Laboratoire de surveillance et d'épidémiologie nutritionnelles en Tunisie, Institut national de nutrition et de technologie alimentaire, Bab Saadoun-Tunis, Tunisie.
authors.forename: Jalila
authors.initials: J
authors.lastname: El Ati
mesh_terms: D003677:Deficiency Diseases / Q000175:diagnosis / Q000652:urine; D005260:Female; D006801:Humans; D007455:Iodine / Q000032:analysis / Q000172:deficiency / Q000652:urine*; D011247:Pregnancy; D011296:Prenatal Diagnosis / Q000379:methods; D016482:Urinalysis / Q000379:methods / Q000592:standards / Q000706:statistics & numerical data
chemical_list: D007455:Iodine
keywords: ICP-MS; Sandell-Kolthoff; diagnosis; iodine; iodine deficiency; urine