title: Lessons learned from a SIRT2-selective inhibitor.
authors.affiliation: Howard Hughes Medical Institute, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA.
authors.forename: Hui
authors.initials: H
authors.lastname: Jing
authors.affiliation: Howard Hughes Medical Institute, Department of Chemistry and Chemical Biology, Cornell University, Ithaca, NY, USA.
authors.forename: Hening
authors.initials: H
authors.lastname: Lin
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D004353:Drug Evaluation, Preclinical / Q000379:methods*; D056572:Histone Deacetylase Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D051379:Mice; D058990:Molecular Targeted Therapy / Q000379:methods*; D009369:Neoplasms / Q000188:drug therapy* / Q000201:enzymology; D010641:Phenotype; D016271:Proto-Oncogene Proteins c-myc / Q000096:biosynthesis / Q000172:deficiency; D056565:Sirtuin 2 / Q000037:antagonists & inhibitors*
chemical_list: D000970:Antineoplastic Agents; D056572:Histone Deacetylase Inhibitors; C489427:MYC protein, human; D016271:Proto-Oncogene Proteins c-myc; C474199:SIRT2 protein, human; D056565:Sirtuin 2
keywords: COMPARE analysis; Myc; oncoprotein; sirtuin; targeted cancer therapy