title: Estimation and correlation of salivary thiocyanate levels in periodontally healthy subjects, smokers, nonsmokers, and gutka-chewers with chronic periodontitis.
abstract: OBJECTIVE
  This study was conducted to estimate and correlate salivary thiocyanate (SCN) levels in periodontally healthy subjects, smokers, nonsmokers, and gutka-chewers with chronic periodontitis.
  
  
  METHODS
  The study population consisted of 40 systemically healthy subjects in the age group of 18-55 years that was further divided into four groups: Control, smokers, nonsmokers, and gutka-chewers with chronic periodontitis. Gingival index (GI) (Loe and Silness-1963), probing depth (PD), clinical attachment loss was assessed. Estimation of SCN was performed by ultraviolet spectrophotometer at 447 nm wavelength. Statistical analysis was performed using the one-way ANOVAs Welch test and Pearson's correlation test using SPSS version 17 software.
  
  
  RESULTS
  Results showed statistically significant increase in SCN levels in smokers as compared to gutka-chewers with chronic periodontitis, control, and nonsmokers with chronic periodontitis subjects. Significantly higher PD and loss of attachment were seen in smokers group compared with other groups. A negative correlation observed between the GI and thiocyanate levels.
  
  
  CONCLUSIONS
  The present study revealed a significant increase in SCN levels in smokers with periodontitis as compared to nonsmokers.
authors.forename: Shashikanth
authors.initials: S
authors.lastname: Hegde
authors.affiliation: Department of Periodontics, Yenepoya Dental College and Hospital, Mangalore, Karnataka, India.
authors.forename: Elashri
authors.initials: E
authors.lastname: Chatterjee
authors.forename: K S
authors.initials: KS
authors.lastname: Rajesh
authors.forename: M S Arun
authors.initials: MS
authors.lastname: Kumar
mesh_terms: D000293:Adolescent; D000328:Adult; D055113:Chronic Periodontitis / Q000175:diagnosis*; D064368:Healthy Volunteers; D006801:Humans; D008875:Middle Aged; D010512:Periodontal Index; D012463:Saliva / Q000737:chemistry; D012907:Smoking / Q000009:adverse effects*; D013861:Thiocyanates / Q000032:analysis*; D014030:Tobacco, Smokeless / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D013861:Thiocyanates