title: Investigating the Familial Basis of Heightened Risk-Taking in Adolescents With Conduct Disorder and Their Unaffected Relatives.
abstract: Previous studies have demonstrated increased risk-taking in adolescents with Conduct Disorder (CD) compared with typically developing controls. Increased risk-taking may partly mediate the pathway from genetic or environmental risk to CD. We investigated the familial basis of risk-taking by examining whether the unaffected relatives of CD probands (n = 22) showed heightened risk-taking in a gambling task, in common with affected probands (n = 44). Adolescents with CD were more likely to select risky options than the typically developing controls (n = 37) and unaffected relatives. Our findings confirm the association between CD and increased risk-taking, but suggest that this decision-making style may not have a familial basis.
authors.affiliation: a Academic Unit of Psychology , University of Southampton , Southampton , United Kingdom.
authors.forename: Kate
authors.initials: K
authors.lastname: Sully
authors.affiliation: a Academic Unit of Psychology , University of Southampton , Southampton , United Kingdom.|b Department of Experimental, Clinical and Health Psychology , Ghent University , Ghent , Belgium.
authors.forename: Edmund J S
authors.initials: EJ
authors.lastname: Sonuga-Barke
authors.affiliation: c School of Psychology , Cardiff University , Cardiff , United Kingdom.
authors.forename: Justin
authors.initials: J
authors.lastname: Savage
authors.affiliation: a Academic Unit of Psychology , University of Southampton , Southampton , United Kingdom.
authors.forename: Graeme
authors.initials: G
authors.lastname: Fairchild
mesh_terms: D000293:Adolescent; D000987:Antisocial Personality Disorder / Q000235:genetics* / Q000523:psychology*; D002755:Choice Behavior; D019955:Conduct Disorder / Q000235:genetics* / Q000523:psychology*; D003657:Decision Making; D005260:Female; D005715:Gambling / Q000235:genetics* / Q000523:psychology*; D006801:Humans; D008297:Male; D012016:Reference Values; D012309:Risk-Taking