title: Analysis of Blood Glucose Distribution Characteristics and Its Risk Factors among a Health Examination Population in Wuhu (China).
abstract: BACKGROUND
  Diabetes mellitus (DM) and Impaired Fasting Glucose (IFG) represent serious threats to human health, and as a result, this study was aimed at understanding the blood glucose distribution characteristics and the risk factors among a large health examination population in China.
  
  
  METHODS
  An investigation with physical and biochemical examinations and questionnaires was conducted in the physical examination center from 2011 to 2014 and as a result 175,122 physical examination attendees were enrolled in this study. Multivariate logistic regression was used to explore the factors influencing blood sugar levels.
  
  
  RESULTS
  The rates of IFG and DM were 6.0% and 3.8%. Prevalence were 7.6%/5.1% in males and 5.1%/2.8% in females for IFG and DM, respectively. The prevalence of IFG and DM were thus higher in males than in females. In the normal group, except high density lipoprotein (HDL) that was significantly higher than in the IFG and DM group, the other indexes (age, body mass index (BMI), glucose (Glu), total cholesterol (TC) and total glycerides (TG) were lower than those in the IFG and DM group. The proportion of IFG and DM also increased with the increases in proportion of abnormal blood pressure, smoking and alcohol consumption. Multivariate logistic regression analysis showed that increasing age, high BMI, high TC, high TG and low HDL increased the risk of diabetes, while in males, in addition to the above factors, the smoking and drinking factors also increased the risk of diabetes. After the age of 65, the blood glucose level reached a peak in males, while in females, the increasing trends was on the rise. The inflexion age of the fast rise was younger in males than in females.
  
  
  CONCLUSIONS
  The study population showed a high prevalence of DM and IFG among the adults. Regular physical examination for the early detection of diabetes is recommended in the high-risk population.
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241002, Anhui, China. songjian_gen@163.com.
authors.forename: Jiangen
authors.initials: J
authors.lastname: Song
authors.affiliation: Department of Physical Examination, Yijishan Hospital of Wannan Medical College, Wuhu 241002, Anhui, China. 13705533568@139.com.
authors.forename: Xiaojuan
authors.initials: X
authors.lastname: Zha
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241002, Anhui, China. haiboli89@163.com.
authors.forename: Haibo
authors.initials: H
authors.lastname: Li
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241002, Anhui, China. guorui0710075@126.com.
authors.forename: Rui
authors.initials: R
authors.lastname: Guo
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241002, Anhui, China. kutuomonk@foxmail.com.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: School of Public Health, Wannan Medical College, Wuhu 241002, Anhui, China. wyf2015w@sina.com.
authors.forename: Yufeng
authors.initials: Y
authors.lastname: Wen
mesh_terms: D000328:Adult; D000368:Aged; D000428:Alcohol Drinking; D001786:Blood Glucose; D015992:Body Mass Index; D002681:China / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D003920:Diabetes Mellitus / Q000453:epidemiology; D050171:Dyslipidemias; D005260:Female; D005947:Glucose; D006801:Humans; D006943:Hyperglycemia / Q000453:epidemiology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011236:Prediabetic State / Q000453:epidemiology*; D015995:Prevalence; D012307:Risk Factors; D012907:Smoking
chemical_list: D001786:Blood Glucose; D002784:Cholesterol; D005947:Glucose
keywords: blood glucose; diabetes; hyperglycaemia; impaired fasting glucose; risk factors