title: Prolonged biochemical response after discontinuation of orteronel (TAK-700) in a patient with metastasized castration-resistant prostate cancer.
authors.affiliation: a Department of Internal Medicine , Sint Franciscus Gasthuis , Rotterdam , The Netherlands.
authors.forename: Laura
authors.initials: L
authors.lastname: Manenschijn
authors.affiliation: a Department of Internal Medicine , Sint Franciscus Gasthuis , Rotterdam , The Netherlands.
authors.forename: Paul
authors.initials: P
authors.lastname: Hamberg
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy* / Q000473:pathology; D000368:Aged; D018931:Antineoplastic Agents, Hormonal / Q000008:administration & dosage / Q000627:therapeutic use; D058070:Asymptomatic Diseases; D065607:Cytochrome P-450 Enzyme Inhibitors / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D007093:Imidazoles / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008297:Male; D009281:Naphthalenes / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D017430:Prostate-Specific Antigen / Q000097:blood*; D064129:Prostatic Neoplasms, Castration-Resistant / Q000188:drug therapy* / Q000473:pathology; D016032:Randomized Controlled Trials as Topic; D013254:Steroid 17-alpha-Hydroxylase / Q000037:antagonists & inhibitors; D028761:Withholding Treatment
chemical_list: D018931:Antineoplastic Agents, Hormonal; D065607:Cytochrome P-450 Enzyme Inhibitors; D007093:Imidazoles; D009281:Naphthalenes; D011239:Prednisolone; C501892:CYP17A1 protein, human; D013254:Steroid 17-alpha-Hydroxylase; D017430:Prostate-Specific Antigen; C571806:orteronel