title: Characteristics of Patients with Chronic Obstructive Pulmonary Disease at the First Visit to a Pulmonary Medical Center in Korea: The KOrea COpd Subgroup Study Team Cohort.
abstract: The Korea Chronic Obstructive Pulmonary Disorders Subgroup Study Team (Korea COPD Subgroup Study team, KOCOSS) is a multicenter observational study that includes 956 patients (mean age 69.9 ± 7.8 years) who were enrolled from 45 tertiary and university-affiliated hospitals from December 2011 to October 2014. The initial evaluation for all patients included pulmonary function tests (PFT), 6-minute walk distance (6MWD), COPD Assessment Test (CAT), modified Medical Research Council (mMRC) dyspnea scale, and the COPD-specific version of St. George's Respiratory Questionnaire (SGRQ-C). Here, we report the comparison of baseline characteristics between patients with early- (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage I and II/groups A and B) and late-stage COPD (GOLD stage III and IV/groups C and D). Among all patients, the mean post-bronchodilator FEV1 was 55.8% ± 16.7% of the predicted value, and most of the patients were in GOLD stage II (520, 56.9%) and group B (399, 42.0%). The number of exacerbations during one year prior to the first visit was significantly lower in patients with early COPD (0.4 vs. 0.9/0.1 vs. 1.2), as were the CAT score (13.9 vs. 18.3/13.5 vs. 18.1), mMRC (1.4 vs. 2.0/1.3 vs.1.9), and SGRQ-C total score (30.4 vs. 42.9/29.1 vs. 42.6) compared to late-stage COPD (all P < 0.001). Common comorbidities among all patients were hypertension (323, 37.7%), diabetes mellitus (139, 14.8%), and depression (207, 23.6%). The data from patients with early COPD will provide important information towards early detection, proper initial management, and design of future studies.
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Chungju Hospital, Chungju, Korea .
authors.forename: Jung Yeon
authors.identifier: 0000-0001-7011-620X
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Chungju Hospital, Chungju, Korea .
authors.forename: Gyu Rak
authors.identifier: 0000-0003-4713-9213
authors.initials: GR
authors.lastname: Chon
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, Seoul St. Mary's Hospital, Seoul, Korea .
authors.forename: Chin Kook
authors.identifier: 0000-0003-4533-7937
authors.initials: CK
authors.lastname: Rhee
authors.affiliation: Department of Internal Medicine, Seoul Metropolitan Government, Seoul National University Boramae Medical Center, Seoul, Korea .
authors.forename: Deog Kyeom
authors.identifier: 0000-0001-9379-8098
authors.initials: DK
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, Yeouido St. Mary's Hospital, Seoul, Korea .
authors.forename: Hyoung Kyu
authors.identifier: 0000-0003-4783-2077
authors.initials: HK
authors.lastname: Yoon
authors.affiliation: Department of Internal Medicine, Medical Research Center, Ewha Womans University Medical Center, Seoul, Korea .
authors.forename: Jin Hwa
authors.identifier: 0000-0003-0843-9862
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea .
authors.forename: Kwang Ha
authors.identifier: 0000-0001-9969-2657
authors.initials: KH
authors.lastname: Yoo
authors.affiliation: Department of Internal Medicine, The Catholic University of Korea, St. Paul's Hospital, Seoul, Korea .
authors.forename: Sang Haak
authors.identifier: 0000-0001-6259-7656
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Korea University Anam Hospital, Korea University College of Medicine, Seoul, Korea .
authors.forename: Sang Yeub
authors.identifier: 0000-0001-7565-1076
authors.initials: SY
authors.lastname: Lee
authors.affiliation: Department of Clinical Pharmacology, Konkuk University Medical Center, Seoul, Korea .
authors.forename: Tae-Eun
authors.identifier: 0000-0001-7598-7602
authors.initials: TE
authors.lastname: Kim
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Hanyang University Guri Hospital, Guri, Korea .
authors.forename: Tae-Hyung
authors.identifier: 0000-0002-3863-7854
authors.initials: TH
authors.lastname: Kim
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Hallym University Medical Center, Seoul, Korea .
authors.forename: Yong Bum
authors.identifier: 0000-0001-8810-6077
authors.initials: YB
authors.lastname: Park
authors.affiliation: Department of Internal Medicine, College of Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea .
authors.forename: Yong Il
authors.identifier: 0000-0002-3502-5211
authors.initials: YI
authors.lastname: Hwang
authors.affiliation: Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea .
authors.forename: Young Sam
authors.identifier: 0000-0001-9656-8482
authors.initials: YS
authors.lastname: Kim
authors.affiliation: Division of Pulmonary Medicine, Department of Internal Medicine, Hallym University Sacred Heart Hospital, Hallym University Medical School, Anyang, Korea .
authors.forename: Ki Suck
authors.identifier: 0000-0002-6878-6543
authors.initials: KS
authors.lastname: Jung
mesh_terms: D000368:Aged; D015331:Cohort Studies; D015897:Comorbidity; D003863:Depression / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000453:epidemiology; D004417:Dyspnea / Q000150:complications; D005260:Female; D005541:Forced Expiratory Volume; D006785:Hospitals, University; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D008168:Lung / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis* / Q000503:physiopathology; D011788:Quality of Life; D056910:Republic of Korea; D012129:Respiratory Function Tests; D012720:Severity of Illness Index; D012955:Societies, Medical; D011795:Surveys and Questionnaires; D062606:Tertiary Care Centers; D000070857:Walk Test
keywords: Pulmonary Disease, Chronic Obstructive; Questionnaires; Respiratory Function Tests