title: [Alcohol-related neuropsychological impairments: Nature, impact and detection].
abstract: Alcohol-related neuropsychological deficits result from chronic and excessive alcohol consumption and are associated with structural and functional damage of Papez's circuit and frontocerebellar circuit. Alcohol-related cognitive deficits are heterogeneous but especially affect executive functions and memory abilities. They result in difficulties to change alcohol behavior combined with a tendency for patients to overestimate their capacity to succeed. Alcohol-related cognitive deficits could be a risk-factor for relapse since they hamper patients to benefit fully from treatment (especially when based on relapse prevention). Screening tools usable by non-psychologists are available and can be completed by an extensive neuropsychological examination conducted by a neuropsychologist when necessary. Alcohol treatment should be adjusted to take alcohol-related cognitive deficits into account, by promoting longer treatment in healthy environment for example. Improvements of alcohol treatment options, including specific neuropsychological rehabilitation, are required for patients with persistent alcohol-related cognitive deficits.
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: François
authors.initials: F
authors.lastname: Vabret
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: Coralie
authors.initials: C
authors.lastname: Lannuzel
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Cabe
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: Ludivine
authors.initials: L
authors.lastname: Ritz
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: Céline
authors.initials: C
authors.lastname: Boudehent
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Eustache
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France.
authors.forename: Anne Lise
authors.initials: AL
authors.lastname: Pitel
authors.affiliation: CHU de Caen, université de Caen Normandie, Inserm, EPHE, unité U1077, GIP Cyceron, 14032 Caen, France. Electronic address: helene.beaunieux@unicaen.fr.
authors.forename: Hélène
authors.initials: H
authors.lastname: Beaunieux
mesh_terms: D000437:Alcoholism / Q000150:complications*; D001927:Brain Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003663:Decision Trees; D006801:Humans