title: Supraglottic jet oxygenation and ventilation during colonoscopy under monitored anesthesia care: a controlled randomized clinical trial.
abstract: OBJECTIVE
  Supraglottic jet oxygenation and ventilation may provide active pulse oxygenation and ventilation in patients with respiratory suppression. This randomized controlled clinical study was designed to determine the efficacy and safety of supraglottic jet oxygenation/ventilation during monitored anesthesia care (MAC) by intravenous (IV) infusion of propofol in patients undergoing colonoscopy.
  
  
  METHODS
  Forty-nine adult patients receiving colonoscopy were randomly divided into two groups: the control group with passive oxygen supply from regular nasal cannula (N = 24) and the supraglottic jet oxygenation/ventilation (SJV) group with active pulse oxygen supply and ventilation using a manual jet ventilator (N = 25). MAC was induced and maintained by intravenous injection of propofol. HR, ECG, BP, SaO2 were continuously monitored during and 1 hour after the procedure.
  
  
  RESULTS
  Demographic characteristics were similar in height, weight, age and BMI (Body Mass Index) between the two groups. Compared to the control group, the SJV group had similar averaged lowest SaO2, but highest SaO2 in SJV group were significantly lower during operation (p = 0.01). The proportion of maximum chest rise movement were increased significantly in SJV group (p = 0.03) compared with control group. Demographic characteristics were similar in the times needed to use facial mask ventilation, percentage of time to maintain SaO2 above 96%, average PetCO2 during the procedure, or complications between the two groups.
  
  
  CONCLUSIONS
  SJV can provide adequate oxygenation/ventilation during monitored anesthesia care and convenient monitoring for patients' breath, without complications.
authors.affiliation: Department of Anesthesiology, International Peace Maternity and Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. yzey15@163.com.
authors.forename: Z-Y
authors.initials: ZY
authors.lastname: Yang
authors.forename: Q
authors.initials: Q
authors.lastname: Meng
authors.forename: Y-H
authors.initials: YH
authors.lastname: Xu
authors.forename: J-W
authors.initials: JW
authors.lastname: Wang
authors.forename: D-S
authors.initials: DS
authors.lastname: Yu
authors.forename: H-F
authors.initials: HF
authors.lastname: Wei
mesh_terms: D000328:Adult; D000758:Anesthesia / Q000379:methods*; D003113:Colonoscopy / Q000379:methods*; D005260:Female; D006611:High-Frequency Jet Ventilation / Q000379:methods*; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D015742:Propofol; D014691:Ventilation
chemical_list: D015742:Propofol