title: Education on electrical phenomena involved in electroporation-based therapies and treatments: a blended learning approach.
abstract: BACKGROUND
  Electroporation-based applications require multidisciplinary expertise and collaboration of experts with different professional backgrounds in engineering and science. Beginning in 2003, an international scientific workshop and postgraduate course electroporation based technologies and treatments (EBTT) has been organized at the University of Ljubljana to facilitate transfer of knowledge from leading experts to researches, students and newcomers in the field of electroporation. In this paper we present one of the integral parts of EBTT: an e-learning practical work we developed to complement delivery of knowledge via lectures and laboratory work, thus providing a blended learning approach on electrical phenomena involved in electroporation-based therapies and treatments.
  
  
  METHODS
  The learning effect was assessed via a pre- and post e-learning examination test composed of 10 multiple choice questions (i.e. items). The e-learning practical work session and both of the e-learning examination tests were carried out after the live EBTT lectures and other laboratory work. Statistical analysis was performed to compare and evaluate the learning effect measured in two groups of students: (1) electrical engineers and (2) natural scientists (i.e. medical doctors, biologists and chemists) undergoing the e-learning practical work in 2011-2014 academic years. Item analysis was performed to assess the difficulty of each item of the examination test.
  
  
  RESULTS
  The results of our study show that the total score on the post examination test significantly improved and the item difficulty in both experimental groups decreased. The natural scientists reached the same level of knowledge (no statistical difference in total post-examination test score) on the post-course test take, as do electrical engineers, although the engineers started with statistically higher total pre-test examination score, as expected.
  
  
  CONCLUSIONS
  The main objective of this study was to investigate whether the educational content the e-learning practical work presented to the students with different professional backgrounds enhanced their knowledge acquired via lectures during EBTT. We compared the learning effect assessed in two experimental groups undergoing the e-learning practical work: electrical engineers and natural scientists. The same level of knowledge on the post-course examination was reached in both groups. The results indicate that our e-learning platform supported by blended learning approach provides an effective learning tool for populations with mixed professional backgrounds and thus plays an important role in bridging the gap between scientific domains involved in electroporation-based technologies and treatments.
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Tržaška c. 25, 1000, Ljubljana, Slovenia. selma.corovic@fe.uni-lj.si.
authors.forename: Selma
authors.initials: S
authors.lastname: Čorović
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Tržaška c. 25, 1000, Ljubljana, Slovenia.
authors.forename: Samo
authors.initials: S
authors.lastname: Mahnič-Kalamiza
authors.affiliation: Faculty of Electrical Engineering, University of Ljubljana, Tržaška c. 25, 1000, Ljubljana, Slovenia.
authors.forename: Damijan
authors.initials: D
authors.lastname: Miklavčič
mesh_terms: D020375:Education, Distance / Q000379:methods*; D053672:Electrochemotherapy; D055724:Electrophysiological Phenomena; D004738:Engineering / Q000193:education; D008051:Lipid Bilayers / Q000737:chemistry / Q000378:metabolism; D008968:Molecular Conformation; D056004:Molecular Dynamics Simulation; D012586:Science / Q000193:education; D012984:Software; D013334:Students
chemical_list: D008051:Lipid Bilayers
keywords: E-learning; Electric field; Electroporation; Electroporation-based technologies and treatments; Item analysis