title: Physiological Bone Remodeling: Systemic Regulation and Growth Factor Involvement.
abstract: Bone remodeling is essential for adult bone homeostasis. It comprises two phases: bone formation and resorption. The balance between the two phases is crucial for sustaining bone mass and systemic mineral homeostasis. This review highlights recent work on physiological bone remodeling and discusses our knowledge of how systemic and growth factors regulate this process.
authors.affiliation: Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, New York.
authors.forename: Jawed A
authors.initials: JA
authors.lastname: Siddiqui
authors.affiliation: Department of Basic Science and Craniofacial Biology, New York University College of Dentistry, New York, New York ncp234@nyu.edu.
authors.forename: Nicola C
authors.initials: NC
authors.lastname: Partridge
mesh_terms: D000818:Animals; D016723:Bone Remodeling / Q000502:physiology*; D001862:Bone Resorption / Q000378:metabolism; D001842:Bone and Bones / Q000378:metabolism*; D002118:Calcium / Q000378:metabolism*; D006706:Homeostasis / Q000502:physiology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D002118:Calcium