title: Acute Glucose Response Properties Beyond Feeding.
abstract: Hypothalamic AgRP neurons potently coordinate feeding behavior to ensure an organism's viability. However, their acute role in glucose-regulatory function remains to be addressed. Steculorum et al. now report that activation of a specific set of AgRP neurons results in an impairment of insulin-stimulated glucose uptake in brown fat through a myogenic signature program.
authors.affiliation: Diabetes, Endocrinology and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD, USA; National Institute on Drug Abuse (NIDA), National Institutes of Health, Baltimore, MD, USA; Brown-NIH Graduate Partnerships Program, Brown University, Providence, RI, USA.
authors.forename: C Joseph
authors.initials: CJ
authors.lastname: Burnett
authors.affiliation: Diabetes, Endocrinology and Obesity Branch, National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health, Bethesda, MD, USA; National Institute on Drug Abuse (NIDA), National Institutes of Health, Baltimore, MD, USA. Electronic address: michael.krashes@nih.gov.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Krashes
mesh_terms: D054369:Agouti-Related Protein; D005247:Feeding Behavior; D005947:Glucose; D007031:Hypothalamus; D009474:Neurons
chemical_list: D054369:Agouti-Related Protein; D005947:Glucose