title: Prevalence and Risk Factors of Carotid Plaque Among Middle-aged and Elderly Adults in Rural Tianjin, China.
abstract: Carotid plaque (CP) is associated with cardiovascular and cerebrovascular events. However, population-based studies with a large sample are rare in China, particularly those in the low-income population. We aimed to determine the prevalence of CP and the associated risk factors in the rural areas of northern China. Between April 2014 and June 2014, we recruited 3789 residents aged ≥45 years. B-mode ultrasonography was performed to measure the extent of CP. The prevalence of CP was 40.3% overall, 47.1% in men, and 35.4% in women (P < 0.001). The prevalence of CP increased with increasing age (P < 0.001). The participants with CP were more likely to have hypertension, diabetes, high total cholesterol (TC) levels, and high low-density lipoprotein-cholesterol levels and be a current smoker; however, they were less likely to be obese. Multiple logistic regression analysis, adjusted for confounders, indicated that age, male sex, hypertension, diabetes, current smoking, and high LDL-C levels were the independent risk factors for CP. There was a lower risk of CP with alcohol consumption. The findings suggest that managing the conventional risk factors is crucial to reduce the burden of cardiovascular and cerebrovascular diseases in the low-income population in China.
authors.affiliation: Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, 241000, China.|Department of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, China.|Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
authors.forename: Changqing
authors.initials: C
authors.lastname: Zhan
authors.affiliation: Department of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, China.|Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
authors.forename: Min
authors.initials: M
authors.lastname: Shi
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing, 100034, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Yang
authors.affiliation: Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, 241000, China.
authors.forename: Hongbo
authors.initials: H
authors.lastname: Pang
authors.affiliation: Department of Neurology, Wuhu No. 2 People's Hospital, Wuhu, Anhui Province, 241000, China.
authors.forename: Shizao
authors.initials: S
authors.lastname: Fei
authors.affiliation: Department of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, China.|Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Bai
authors.affiliation: Department of Ultrasound, Tianjin Huanhu Hospital, Tianjin, 300060, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, China.|Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Tu
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing, 100034, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huo
authors.affiliation: Department of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, China.|Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
authors.forename: Xianjia
authors.initials: X
authors.lastname: Ning
authors.affiliation: Department of Cardiology, Peking University First Hospital, Beijing, 100034, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology, Tianjin Neurological Institute, Tianjin, 300052, China.|Department of Neurology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
authors.forename: Jinghua
authors.initials: J
authors.lastname: Wang
mesh_terms: D000367:Age Factors; D000368:Aged; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000473:pathology*; D002681:China / Q000453:epidemiology; D002784:Cholesterol / Q000097:blood; D003920:Diabetes Mellitus / Q000503:physiopathology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000503:physiopathology; D008077:Lipoproteins, LDL / Q000097:blood; D008297:Male; D008875:Middle Aged; D058226:Plaque, Atherosclerotic / Q000000981:diagnostic imaging / Q000191:economics / Q000453:epidemiology* / Q000473:pathology*; D011203:Poverty; D015995:Prevalence; D012307:Risk Factors; D012424:Rural Population; D012737:Sex Factors; D012907:Smoking / Q000503:physiopathology; D014280:Triglycerides / Q000097:blood; D014463:Ultrasonography / Q000379:methods
chemical_list: D008077:Lipoproteins, LDL; D014280:Triglycerides; D002784:Cholesterol