title: A Case Report: Hybrid Treatment Approach to Lipoid Proteinosis of the Larynx.
abstract: OBJECTIVE
  Previous research on treatment of lipoid proteinosis has focused on genetic etiology and clinical diagnosis of this rare laryngeal disorder. However, few studies on this disorder have examined treatment methods directed at improving voice qualities. The purpose of this study was to examine a novel hybrid treatment approach and its improvements in the patient's voice quality.
  
  
  METHODS
  In this case study, a 27-year-old man complaining of hoarseness of voice and effortful phonation was diagnosed with lipoid proteinosis. He was then prescribed a combination of surgical intervention and voice therapy to improve his overall voice quality.
  
  
  RESULTS
  The results of the posttreatment evaluation demonstrate significant improvements in both objective and subjective voice quality measurements.
  
  
  CONCLUSIONS
  A further examination of this hybrid approach in the treatment of lipoid proteinosis is warranted to determine its efficacy.
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, The Eye and ENT Hospital of Fudan University, Shanghai, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Chen
authors.affiliation: Department of Surgery, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin.
authors.forename: William
authors.initials: W
authors.lastname: Calawerts
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, The Eye and ENT Hospital of Fudan University, Shanghai, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, The Eye and ENT Hospital of Fudan University, Shanghai, China; Department of Surgery, University of Wisconsin Madison School of Medicine and Public Health, Madison, Wisconsin.
authors.forename: Jack
authors.initials: J
authors.lastname: Jiang
authors.affiliation: Department of Otorhinolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China.. Electronic address: xuwendoc@126.com.
authors.forename: Wen
authors.initials: W
authors.lastname: Xu
mesh_terms: D000328:Adult; D003131:Combined Modality Therapy; D006685:Hoarseness / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D007828:Laryngoscopy; D008065:Lipoid Proteinosis of Urbach and Wiethe / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D008297:Male; D008866:Microsurgery / Q000379:methods*; D010699:Phonation; D020127:Recovery of Function; D049489:Stroboscopy; D016896:Treatment Outcome; D014833:Voice Quality; D014834:Voice Training
keywords: Diagnosis; Lipoid proteinosis; Microphonosurgery; Treatment; Voice therapy