title: A potential role for cytomegalovirus in a facial ulcer in a renal transplant recipient.
abstract: Cytomegalovirus infection (CMV) is a well-known consequence of immunosuppression and one of the expected pathogens in recipients of solid organs such as renal transplant recipients (RTRs). Infection by CMV in immunocompromised settings can be life-threatening since many organs are involved and affected. Skin involvement has been rarely reported. In this report, we present a highly immunosuppressed RTR with CMV infection manifested as ulcerative skin lesions on the face, along with allograft dysfunction diagnosed by biopsy of the skin and the renal allograft, in addition to the presence of viral DNA in the tissue and antigenemia, which resolved following antiviral treatment. To the best of our knowledge, this is the first report in the literature of facial skin involvement induced by CMV in an RTR. This report emphasizes the value of early biopsy in RTRs with skin lesions and highlights CMV infection as a possible etiology.
authors.affiliation: Shiraz Nephrology Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: S
authors.initials: S
authors.lastname: Ezzatzadegan Jahromi
authors.affiliation: Kidney Transplantation Complications Research Center, Montaserie Organ Transplantation Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
authors.forename: Z
authors.initials: Z
authors.lastname: Lotfi
authors.affiliation: Shiraz Nephrology Urology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: S
authors.initials: S
authors.lastname: Torabi-Nezhad
authors.affiliation: Department of Pathology, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: F S
authors.initials: FS
authors.lastname: Aslani
authors.affiliation: Prof. Alborzi Clinical Microbiology Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran.
authors.forename: B
authors.initials: B
authors.lastname: Pourabbas
keywords: cytomegalovirus; renal transplantation; skin ulcer