title: Pregnancy is not a risk factor for idiopathic sudden sensorineural hearing loss: A nationwide population-based study.
abstract: CONCLUSIONS
  Sudden sensorineural hearing loss (SSNHL) in pregnancy is rare. It usually occurs in the third trimester. SSNHL in pregnancy does not increase risks during delivery or subsequent stroke.
  
  
  OBJECTIVE
  This study aimed to investigate the incidence and to determine the factors associated with SSNHL in pregnancy.
  
  
  METHODS
  Data were retrieved from Taiwan's National Health Insurance Database (NHIRD), covering the years 2000-2009. Patients admitted for SSNHL during pregnancy were enrolled. An age-matched controlled cohort was randomly selected from pregnant women without SSNHL in the NHIRD. The clinical characteristics of both cohorts were collected for further analyses.
  
  
  RESULTS
  Thirty-three patients with SSNHL in pregnancy were enrolled. The estimated incidence of SSNHL in pregnancy in Taiwan was 2.71 per 100,000 pregnancies. The incidence of SSNHL in pregnancy was lower than that of the general female population. The incidence of SSNHL in the third trimester was higher compared to the other two. The incidence of SSNHL occurring in the 30-39 years old age group was higher than other groups. Women with better socioeconomic status had a higher incidence of SSNHL. There were no identified systemic diseases before SSNHL. Two patients had pre-eclampsia and one patient had premature delivery. Nevertheless, SSNHL in pregnancy did not increase the risk for stroke.
authors.affiliation: a Department of Otolaryngology , Taichung Veterans General Hospital , Taichung , Taiwan ;|b Graduate Institute of Natural Healing Sciences, Nanhua University , Cha-Yi , Taiwan ;|c Department of Medicine , National Yang-Ming Medical University , Taipei , Taiwan ;
authors.forename: Ting-Ting
authors.initials: TT
authors.lastname: Yen
authors.affiliation: d Department of Medical Research , Taichung Veterans General Hospital , Taichung , Taiwan ;
authors.forename: Ching-Heng
authors.initials: CH
authors.lastname: Lin
authors.affiliation: a Department of Otolaryngology , Taichung Veterans General Hospital , Taichung , Taiwan ;|c Department of Medicine , National Yang-Ming Medical University , Taipei , Taiwan ;
authors.forename: Jiun-Yih
authors.initials: JY
authors.lastname: Shiao
authors.affiliation: a Department of Otolaryngology , Taichung Veterans General Hospital , Taichung , Taiwan ;|c Department of Medicine , National Yang-Ming Medical University , Taipei , Taiwan ;|e School of Medicine, Chung Shan Medical University , Taichung , Taiwan.
authors.forename: Kai-Li
authors.initials: KL
authors.lastname: Liang
mesh_terms: D000328:Adult; D015331:Cohort Studies; D005260:Female; D006319:Hearing Loss, Sensorineural / Q000453:epidemiology*; D003639:Hearing Loss, Sudden / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology; D013624:Taiwan / Q000453:epidemiology
keywords: Incidence rate; pregnancy; stroke; sudden deafness; sudden sensorineural hearing loss