title: The Effects of Two Novel Copper-Based Formulations on Helicobacter pylori.
abstract: We investigated the effects of two novel copper-based inorganic formulations for their activity against 60 isolates of Helicobacter pylori (Hp). The two copper-based formulations were tested against three NCTC Helicobacter pylori isolates and 57 clinical strains isolated from the UK and Italy in time-kill assays. Both copper-based formulations were bio-cidal against all Helicobacter pylori strains tested reducing the viable count by 4-5 log within 2 h. These two copper-based anti-microbial agents deserve further study in relation to the treatment of H. pylori-related gastric disease.
authors.affiliation: First Medical Clinic, University of Bologna, Bologna 40121, Italy. iliaria.saracino@unibo.it.
authors.forename: Ilaria M
authors.initials: IM
authors.lastname: Saracino
authors.affiliation: First Medical Clinic, University of Bologna, Bologna 40121, Italy. crysette@hotmail.it.
authors.forename: Cristina
authors.initials: C
authors.lastname: Zaccaro
authors.affiliation: First Medical Clinic, University of Bologna, Bologna 40121, Italy. giovanna.lore@studio.unibo.it.
authors.forename: Giovanna Lo
authors.initials: GL
authors.lastname: Re
authors.affiliation: First Medical Clinic, University of Bologna, Bologna 40121, Italy. beradino.vaira@unibo.it.
authors.forename: Dino
authors.initials: D
authors.lastname: Vaira
authors.affiliation: Department of Health & Social Sciences, University of Middlesex, NW4 4Bt London, UK. john.holton@nhs.net.
authors.forename: John
authors.initials: J
authors.lastname: Holton
keywords: bactericidal; copper; helicobacter; novel formulation