title: Pharmacokinetic analysis of gefitinib in a patient with advanced non-small cell lung cancer undergoing hemodialysis.
abstract: Patients undergoing hemodialysis (HD) are frequently elderly with poor performance status and usually cannot withstand chemotherapy because of its toxicities. We report a case of an elderly woman with chronic renal failure undergoing HD who was diagnosed with advanced non-small cell lung cancer and treated with orally administered gefitinib. We analyzed the pharmacokinetic data of gefitinib in this patient and found that that gefitinib was safe under these conditions.
authors.affiliation: Respiratory Department Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
authors.forename: Jinmei
authors.initials: J
authors.lastname: Luo
authors.affiliation: Respiratory Department Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
authors.forename: Li
authors.initials: L
authors.lastname: Ni
authors.affiliation: Respiratory Department Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
authors.forename: Mengzhao
authors.initials: M
authors.lastname: Wang
authors.affiliation: Respiratory Department Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhong
authors.affiliation: Respiratory Department Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: Department of Nephrology Peking Union Medical College Hospital Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
authors.forename: Ke
authors.initials: K
authors.lastname: Zheng
authors.affiliation: Clinical Pharmacology Research Center Peking Union Medical College Hospital Peking Union Medical College Chinese Academy of Medical Sciences Beijing China.
authors.forename: Pei
authors.initials: P
authors.lastname: Hu
keywords: Gefitinib; lung cancer; renal failure