title: Burden of Malaria in Iran, 1990-2010: Findings from the Global Burden of Disease Study 2010.
abstract: BACKGROUND
  Malaria is a major public health challenge in tropical and semi-tropical countries in terms of high morbidity and mortality. The present study aimed to report the burden of malaria in Iran, extracted from the global burden of disease 2010 study (GBD 2010) covering the period 1990 to 2010, to compare these findings with similar results, and to present some recommendations as potential solutions for gaining more accurate estimations regarding the burden of the disease in Iran.
  
  
  METHODS
  Data covering the period from 1990 to 2010 were derived from the GBD 2010, which is published by the Institute for Health Metrics and Evaluation (IHME). The findings were used to estimate the years lived with disability (YLDs), the years of life lost (YLLs), the disability-adjusted life-years (DALYs), and the death rate of malaria in Iran.
  
  
  RESULTS
  The GBD 2010 estimated that there was a sharp declining death trend with regard to DALYs and death rate, showing that 4,647.63 DALYs were due to malaria in Iranian people of all ages and both genders, and that DALYs per 100,000 individuals declined from 37.15 in 1990 to 5.87 in 2010. The total number of malaria deaths over the 20 years was 73.37.
  
  
  CONCLUSIONS
  The findings revealed that the burden of malaria decreased remarkably between 1990 and 2010. The explanation for this decrease is the establishment of a malaria surveillance system in various parts of Iran, and utilization of proper intervention and the improvement of infrastructures, which play a role in disease transmission, especially in endemic areas.
authors.affiliation: 1)Department of Medical Parasitology and Mycology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran. 2)Department of Microbiology and Immunology, Faculty of Medicine, Qom University of Medical Sciences, Qom, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Badirzadeh
authors.affiliation: 3)Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran. 4)Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Shohreh
authors.initials: S
authors.lastname: Naderimagham
authors.affiliation: Department of Environmental Health Engineering, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Zahra
authors.initials: Z
authors.lastname: Asadgol
authors.affiliation: School of Public Health, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Yaser
authors.initials: Y
authors.lastname: Mokhayeri
authors.affiliation: Department of Biostatistics, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
authors.forename: Azin
authors.initials: A
authors.lastname: Khosravi
authors.affiliation: Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
authors.forename: Elham
authors.initials: E
authors.lastname: Tohidnejad
authors.affiliation: 9)Health Sector Policy Coordination Group, in Charge of Minister for Policy Making Affairs Bureau, Ministry of Health and Medical Education, Tehran, Iran. 3)Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Vosoogh-Moghaddam
authors.affiliation: Department of Epidemiology, School of Medicine, Aja University of Medical Sciences, Tehran, Iran.
authors.forename: Ali
authors.initials: A
authors.lastname: Khoshdel
authors.affiliation: 4)Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Research Institute, Tehran University of Medical Sciences, Tehran, Iran. 3)Non-communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute,Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Nazila
authors.initials: N
authors.lastname: Rezaei
authors.affiliation: Department of Hematology and Oncology, Children's Hospital Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Farzad
authors.initials: F
authors.lastname: Kompani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D006233:Persons with Disabilities / Q000706:statistics & numerical data*; D005260:Female; D000071219:Global Burden of Disease / Q000639:trends*; D006306:Health Surveys; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008288:Malaria / Q000453:epidemiology* / Q000401:mortality / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D011159:Population Surveillance; D019057:Quality-Adjusted Life Years; D055815:Young Adult