title: Dioxazoles, a new mild nitrene transfer reagent in gold catalysis: highly efficient synthesis of functionalized oxazoles.
abstract: A gold-catalyzed regioselective [3+2] cycloaddition of ynamides with 1,4,2-dioxazoles was developed and offers a novel approach to obtain highly functionalized oxazoles under mild reaction conditions. 1,4,2-Dioxazole was found to act as an efficient N-acyl nitrene equivalent to trigger a facile generation of α-imino gold-carbene intermediate through the elimination of a ketone.
authors.affiliation: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 345 Lingling Road, Shanghai 200032, China. yhliu@sioc.ac.cn.
authors.forename: Ming
authors.initials: M
authors.lastname: Chen
authors.forename: Ning
authors.initials: N
authors.lastname: Sun
authors.forename: Haoyi
authors.initials: H
authors.lastname: Chen
authors.forename: Yuanhong
authors.initials: Y
authors.lastname: Liu