title: Urethroplasty Improves Overactive Bladder Symptoms in Men With Anterior Urethral Strictures.
abstract: OBJECTIVE
  To assess the effect of urethroplasty on overactive bladder (OAB) symptoms.
  
  
  METHODS
  From March 2011 to November 2014, 47 anterior urethroplasties were performed by a single surgeon (RSP). Of these, 42 men prospectively completed the validated Overactive Bladder Symptom Score (OABSS) prior to and after urethroplasty. Comparative analysis of preoperative to postoperative OABSS results was performed.
  
  
  RESULTS
  The median (range) age of men who comprised our cohort was 49 (22-90). Questionnaires were completed preoperatively and at a median of 12 months (2.3-74.6) postoperatively. Stricture location included the following: bulbar (75%), penile (15%), and membranous (7.5%) urethra. Median stricture length was 3 cm (1-6). Half of the men underwent an excision and anastomotic repair, and half underwent buccal mucosal graft. Men experienced significant improvement in urinary flow rate, postvoid residual urine, and OAB symptoms reported on the OABSS. Of the 28/42 men with preoperative, clinically significant OAB (ie, OABSS ≥ 8), 25/28 reported a 54.2% (0%-100%) median reduction in OABSS, with only 1 patient reporting worsening of symptoms following surgery. Those men with the highest preoperative OABSS experienced the greatest improvement in OAB symptoms postoperatively.
  
  
  CONCLUSIONS
  In men with anterior urethral strictures and OAB, urethroplasty decreased reported OABSS by >50% and cured 90% of men with clinically significant OAB symptoms.
authors.affiliation: Department of Urology, University of California, San Francisco, CA. Electronic address: charlesosterberg@gmail.com.
authors.forename: E Charles
authors.initials: EC
authors.lastname: Osterberg
authors.affiliation: Department of Urology, Weill Cornell Medical College, New York, NY.
authors.forename: Michael
authors.initials: M
authors.lastname: Schulster
authors.affiliation: Department of Urology, Weill Cornell Medical College, New York, NY.
authors.forename: Jerry G
authors.initials: JG
authors.lastname: Blaivas
authors.affiliation: Department of Urology, University of Pittsburgh Medical Center, Pittsburgh, PA.
authors.forename: Avinash
authors.initials: A
authors.lastname: Maganty
authors.affiliation: Department of Urology, Weill Cornell Medical College, New York, NY.
authors.forename: Daniel J
authors.initials: DJ
authors.lastname: Lee
authors.affiliation: Department of Urology, Weill Cornell Medical College, New York, NY.
authors.forename: Rajveer S
authors.initials: RS
authors.lastname: Purohit
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D059026:Diagnostic Self Evaluation; D006801:Humans; D008297:Male; D008875:Middle Aged; D012074:Remission Induction; D014521:Urethra / Q000601:surgery*; D014525:Urethral Stricture / Q000150:complications* / Q000473:pathology / Q000601:surgery*; D053201:Urinary Bladder, Overactive / Q000209:etiology* / Q000601:surgery*; D013520:Urologic Surgical Procedures / Q000379:methods; D055815:Young Adult