title: [Assessment of transmammary transmission of Trichinella patagoniensis in BALB/c mice].
abstract: Since 1916 to date, it has been suspected that vertical transmission of parasites from the genus Trichinella could occur in pregnant or lactating women during the parenteral phase of infection. The aim of the present study was to evaluate the transmammary transmission of T. patagoniensis in BALB/c mice. Twenty 7-week-old BALB/c mice were distributed into two groups of 10 individuals each, depending on the time of gestation when they were infected, 15 or 18 days after detection of the vaginal plug. Each group was subdivided into two subgroups of 5 mice each, which were given an oral dose of 100 or 500 infective larvae respectively. Euthanasia and subsequent artificial digestion was performed in the pups and the dams. No T. patagoniensis L1 larvae were found in any of the offsprings analyzed. The observed results suggest that vertical transmission of T. patagoniensis would not be possible in BALB/c mice.
authors.affiliation: Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (FCV-UBA), CABA, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), CABA, Argentina. Electronic address: fernandoaf@fvet.uba.ar.
authors.forename: Fernando A
authors.initials: FA
authors.lastname: Fariña
authors.affiliation: Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (FCV-UBA), CABA, Argentina.
authors.forename: Mariana I
authors.initials: MI
authors.lastname: Pasqualetti
authors.affiliation: Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (FCV-UBA), CABA, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), CABA, Argentina.
authors.forename: Natalia M
authors.initials: NM
authors.lastname: Cardillo
authors.affiliation: Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (FCV-UBA), CABA, Argentina.
authors.forename: Tatiana
authors.initials: T
authors.lastname: Aronowicz
authors.affiliation: Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (FCV-UBA), CABA, Argentina.
authors.forename: Mariano
authors.initials: M
authors.lastname: Ercole
authors.affiliation: Departamento de Parasitología, INEI, ANLIS, «Dr. Carlos Malbrán», CABA, Argentina.
authors.forename: Silvio J
authors.initials: SJ
authors.lastname: Krivokapich
authors.affiliation: Cátedra de Parasitología y Enfermedades Parasitarias, Facultad de Ciencias Veterinarias, Universidad de Buenos Aires (FCV-UBA), CABA, Argentina.
authors.forename: Mabel M
authors.initials: MM
authors.lastname: Ribicich
mesh_terms: D000818:Animals; D000833:Animals, Suckling; D005260:Female; D018445:Infectious Disease Transmission, Vertical; D007814:Larva; D008321:Mammary Glands, Animal / Q000469:parasitology; D051379:Mice; D008807:Mice, Inbred BALB C / Q000469:parasitology*; D008892:Milk / Q000469:parasitology*; D009132:Muscles / Q000469:parasitology; D011247:Pregnancy; D013045:Species Specificity; D014234:Trichinella / Q000302:isolation & purification / Q000472:pathogenicity*; D014235:Trichinellosis / Q000635:transmission*
keywords: BALB/c; Congenital trichinellosis; Transmisión vertical; Trichinella patagoniensis; Trichinellosis congénita; Vertical transmission