title: Results of transnasal transostial sphenoidotomy in 79 cases of chronic sphenoid sinusitis.
abstract: OBJECTIVE
  This study was designed to retrospectively review the postoperative results of transnasal transostial sphenoidotomy in 79 patients with isolated chronic sphenoid sinusitis operated between 1995 and 2013 and evaluate the recurrence rate due to postoperative closure of the sphenoidotomy.
  
  
  METHODS
  Seventy-nine patients, 44 women and 35 men (M:F sex ratio: 0.79) aged 10 to 84 years (mean age: 48), were included. The most common presenting symptom was headache in 61% of cases. Visual disturbances were present in three cases. The diagnostic work-up comprised nasal endoscopy, computed tomography (CT) and magnetic resonance imaging (MRI) of the sinuses. The surgical indication was based on failure of antibiotic therapy and/or the nature and severity of sphenoid sinusitis. All patients were operated by endoscopic transnasal transostial sphenoidotomy. Samples were taken for histological, bacteriological and mycological examination.
  
  
  RESULTS
  No intraoperative or immediate postoperative complications were observed. Nature of the lesion: forty-seven patients (59.5%) presented nonspecific inflammatory lesions with negative bacterial or fungal culture and inflammatory mucosal changes, 19 patients (24%) had fungal sinusitis presenting as a fungus ball and 13 patients (16.4%) had documented bacterial sinusitis. Mean postoperative follow-up was 7.4 months (range: 6-48). No recurrence of the sinusitis or symptoms was observed in 71 cases (89.8%). Recurrence: eight cases (10.2%) of postoperative closure of the sphenoidotomy were observed, requiring one (6 cases) or several (2 cases) reoperations with a mean of 16.4 months after the initial procedure. Symptoms of recurrence consisted of varying degrees of headache, with similar symptoms to those of the first episode in 7 cases, and retro-orbital headache in 1 case. Reoperation was performed via a transnasal transostial approach in 6 cases and a transethmoidal approach in 2 cases.
  
  
  CONCLUSIONS
  The transnasal transostial surgical approach is a safe and effective procedure for the treatment of isolated sphenoid sinusitis. However, the recurrence rate due to postoperative closure of the sphenoidotomy observed in our series raises the question of postoperative maintenance of a patent and functional sphenoidotomy.
authors.affiliation: Service ORL et chirurgie cervico-faciale, CHU, université d'Auvergne, 58, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: J
authors.initials: J
authors.lastname: Massoubre
authors.affiliation: Service ORL et chirurgie cervico-faciale, CHU, université d'Auvergne, 58, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: N
authors.initials: N
authors.lastname: Saroul
authors.affiliation: Service ORL et chirurgie cervico-faciale, centre hospitalier Essos, Yaoundé, Cameroon.
authors.forename: J-E
authors.initials: JE
authors.lastname: Vokwely
authors.affiliation: Service ORL et chirurgie cervico-faciale, CHU, université d'Auvergne, 58, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: B
authors.initials: B
authors.lastname: Lietin
authors.affiliation: Service ORL et chirurgie cervico-faciale, CHU, université d'Auvergne, 58, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: T
authors.initials: T
authors.lastname: Mom
authors.affiliation: Service ORL et chirurgie cervico-faciale, CHU, université d'Auvergne, 58, rue Montalembert, 63000 Clermont-Ferrand, France. Electronic address: lgilain@chu-clermontferrand.fr.
authors.forename: L
authors.initials: L
authors.lastname: Gilain
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D057605:Natural Orifice Endoscopic Surgery / Q000379:methods*; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D013101:Sphenoid Sinus / Q000601:surgery*; D015524:Sphenoid Sinusitis / Q000175:diagnosis / Q000382:microbiology / Q000601:surgery*; D055815:Young Adult
keywords: Fungus ball; Sphenoid sinusitis; Sphenoidotomy; Stenosis; Transostial