title: Flagellate Pattern of Toxic Erythema of Chemotherapy Due to Doxorubicin: A Case Report.
abstract: BACKGROUND
  Doxorubicin is an antineoplastic agent frequently used in diverse cancer regimens. Cutaneous adverse effects have frequently been reported with its use. However, a flagellate-like dermatitis is not mentioned in the literature.
  
  
  OBJECTIVE
  The investigators report a case of toxic erythema of chemotherapy with a flagellate pattern induced by doxorubicin.
  
  
  RESULTS
  A 75-year-old woman with endometrial cancer received doxorubicin as part of her treatment. After her third cycle, she presented a pruritic vesiculobullous eruption, with linear elements that left hyperpigmented streaks on follow-up. A biopsy was compatible with a drug eruption.
  
  
  CONCLUSIONS
  Doxorubicin is a well-known cause of toxic erythema of chemotherapy. As seen in this patient, the investigators suggest that it also be added to the list of causes of flagellate dermatosis.
authors.affiliation: Division of Dermatology, Université de Montréal, Montreal, QC, Canada sophie.vadeboncoeur@umontreal.ca.
authors.forename: Sophie
authors.initials: S
authors.lastname: Vadeboncoeur
authors.affiliation: Division of Dermatology, Université de Montréal, Montreal, QC, Canada.
authors.forename: Benoît
authors.initials: B
authors.lastname: Côté
mesh_terms: D000368:Aged; D000903:Antibiotics, Antineoplastic / Q000009:adverse effects*; D004317:Doxorubicin / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology / Q000473:pathology*; D016889:Endometrial Neoplasms / Q000188:drug therapy*; D004890:Erythema / Q000139:chemically induced / Q000473:pathology*; D005260:Female; D006801:Humans
chemical_list: D000903:Antibiotics, Antineoplastic; D004317:Doxorubicin
keywords: dermatology; doxorubicin; flagellate dermatitis; inflammatory dermatosis; toxic erythema of chemotherapy