title: Comparison of Transcatheter Aortic Valve Implantation versus Surgical Aortic Valve Replacement to Improve Quality of Life in Patients >70 Years of Age with Severe Aortic Stenosis.
abstract: OBJECTIVE
  Transcatheter aortic valve implantation has recently been used in the treatment of severe aortic valve stenosis, particularly in patients with high mortality and morbidity rates for open surgery. The purpose of this study was to compare quality of life in patients over 70 years of age undergoing surgical or transcatheter aortic valve implantation, before the procedure and in the early post-procedural period.
  
  
  METHODS
  Seventy-nine patients were included in the study, 38 (48.1%) male and 41 (51.9%) female. Mean age of patients was 74.3±5.2 (70-91) years. The surgical aortic valve replacement group consisted of 51 (64.6%) patients and the transcatheter aortic valve replacement group of 28 (35.4%). Quality of life data before the procedure and at the 3rd month postoperatively in patients aged 70 years and older undergoing surgical or transcatheter aortic valve implantation were assessed using the 36-item Short Form Health Survey form.
  
  
  RESULTS
  Positive increases in physical task difficulty (13.2±9.8vs. 5.1±7.3) (P=0.001), emotional task difficulty (14.4±11.9 vs.8.5±6.4) (P=0.035), and mental health (0.4±10.4 vs. 9.6±15.1) (P=0.001; P<0.01) scores in patients undergoing transcatheter aortic valve replacement were significantly higher compared to the surgical aortic valve replacement group. No statistically significant difference was determined between the groups in terms of pain, vitality, social function, physical function or general health scores in the preoperative and postoperative periods.
  
  
  CONCLUSIONS
  The positive increase in quality of life parameters in the transcatheter aortic valve implantation group at the 3rd month postoperatively was significantly higher compared to the surgical aortic valve replacement group.
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Cemal
authors.initials: C
authors.lastname: Kocaaslan
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Bülend
authors.initials: B
authors.lastname: Ketenci
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Yılmaz
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Tamer
authors.initials: T
authors.lastname: Kehlibar
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Mehmet Erdem
authors.initials: ME
authors.lastname: Memetoğlu
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Ertaş
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eren
authors.affiliation: Dr.Siyami Ersek Cardiovascular and Thoracic Surgery Hospital, İstanbul, Turkey.
authors.forename: Mahmut Murat
authors.initials: MM
authors.lastname: Demirtaş
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001021:Aortic Valve / Q000601:surgery*; D001024:Aortic Valve Stenosis / Q000601:surgery*; D005260:Female; D006350:Heart Valve Prosthesis; D006801:Humans; D008297:Male; D011184:Postoperative Period; D057234:Preoperative Period; D011446:Prospective Studies; D011788:Quality of Life; D018570:Risk Assessment; D012307:Risk Factors; D018709:Statistics, Nonparametric; D013997:Time Factors; D065467:Transcatheter Aortic Valve Replacement / Q000379:methods*; D016896:Treatment Outcome