title: New Efficient Synthesis of 3,4-Dihydropyrimidin-2(1H)-ones Catalyzed by Benzotriazolium-Based Ionic Liquids under Solvent-Free Conditions.
abstract: An efficient synthesis of novel 3,4-dihydropyrimidin-2(1H)-ones (DHPMs) and their derivatives, using Brønsted acidic ionic liquid [C₂O₂BBTA][TFA] as a catalyst, from the condensation of aryl aldehyde, β-ketoester and urea was described. Reactions proceeded smoothly for 40 min under solvent-free conditions and gave the desirable products with good to excellent yields (up to 99%). The catalyst could be easily recycled and reused with similar eﬃcacies for at least six cycles.
authors.affiliation: Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China. 15293606480@163.com.
authors.forename: Zhiqing
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China. marong19851208@126.com.
authors.forename: Rong
authors.initials: R
authors.lastname: Ma
authors.affiliation: Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China. lzxlxx123@126.com.
authors.forename: Dawei
authors.initials: D
authors.lastname: Cao
authors.affiliation: Key Laboratory of Oil and Gas Fine Chemicals of Ministry of Education, School of Chemistry and Chemical Engineering, Xinjiang University, Urumqi 830046, China. pxylcj@126.com.|Physics and Chemistry Detecting Center, Xinjiang University, Urumqi 830046, China. pxylcj@126.com.
authors.forename: Chenjiang
authors.initials: C
authors.lastname: Liu
mesh_terms: D000447:Aldehydes / Q000737:chemistry; D002384:Catalysis; D052578:Ionic Liquids / Q000737:chemistry*; D011744:Pyrimidinones / Q000138:chemical synthesis* / Q000737:chemistry; D012997:Solvents / Q000737:chemistry; D014508:Urea / Q000737:chemistry
chemical_list: D000447:Aldehydes; D052578:Ionic Liquids; D011744:Pyrimidinones; D012997:Solvents; D014508:Urea
keywords: Benzotriazolium-based ionic liquids; Biginelli reaction; catalysis; synthesis