title: Facial rejuvenation via the sequential combined use of multiple laser modalities: Safety and efficacy.
abstract: Multi-modal combination treatments for facial rejuvenation offer the potential to achieve superior results in a single treatment session. In this study, we evaluate the safety and efficacy of combining multiple laser modalities in a single treatment session.
  
  
  
  Fifty patients underwent a multi-modal facial laser resurfacing procedure consisting of the sequential use of 595 nm pulsed dye laser, 755 nm alexandrite laser, superficial fractionated and fully ablative CO2 laser, superficial fully ablative erbium-YAG laser, and deep fractionated ablative CO2 laser in a single treatment session. Improvements in dyspigmentation, rhytides, telangiectasia, and skin texture were assessed. Patient satisfaction, healing times, and tolerability of procedure was also evaluated.
  
  
  
  Highly significant improvements in all clinical parameters were demonstrated at both short- and long-term follow-up evaluations. Patients reported a high satisfaction rate.
  
  
  
  Mega-combination treatment utilizing a variety of laser devices in a single treatment session is safe and highly effective at achieving facial rejuvenation. This approach represents an efficient use of both patient and physician time and resources. Lasers Surg. Med. 48:577-583, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Goldman, Butterwick, Groff, Fabi, and Wu, Cosmetic Laser Dermatology, 9339 Genesee Avenue, Suite 300, San Diego, California, 92121.
authors.forename: Douglas C
authors.initials: DC
authors.lastname: Wu
authors.affiliation: Goldman, Butterwick, Groff, Fabi, and Wu, Cosmetic Laser Dermatology, 9339 Genesee Avenue, Suite 300, San Diego, California, 92121.
authors.forename: Richard E
authors.initials: RE
authors.lastname: Fitzpatrick
mesh_terms: D003357:Cosmetic Techniques; D062109:Dermatologic Surgical Procedures / Q000379:methods*; D005145:Face; D005500:Follow-Up Studies; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D054025:Lasers, Dye / Q000627:therapeutic use; D054020:Lasers, Gas / Q000627:therapeutic use; D053844:Lasers, Solid-State / Q000627:therapeutic use; D017060:Patient Satisfaction / Q000706:statistics & numerical data; D010859:Pigmentation Disorders / Q000601:surgery*; D012060:Rejuvenation; D012189:Retrospective Studies; D015595:Skin Aging; D013684:Telangiectasis / Q000601:surgery*; D016896:Treatment Outcome
keywords: CO2 laser; alexandrite; combination treatment; facial rejuvenation; laser resurfacing; pulsed dye laser