title: Postoperative Quality of Life in Patients with Ileal Neobladder at Short-, Intermediate- and Long-Term Follow-Up.
abstract: BACKGROUND
  To evaluate the difference at different steps of follow-up of the postoperative quality of life (QoL) in patients who had undergone radical cystectomy and ileal orthotopic neobladder derivation.
  
  
  METHODS
  A multicentric, cross-qualitative study was performed in 5 Italian centers of reference for the treatment of bladder cancer. One hundred seventy one patients who underwent radical cystectomy and creation of ileal orthotopic neobladder according to 'Vescica Ileale Padovana' between 2006 and 2011 have been analyzed. The validated and dedicated questionnaires EORTC QLQ-C30, IOB-PRO and EORTC QLQ-BLM30 were used.
  
  
  RESULTS
  All data gathered were then processed, specifically means ± SD were included for comparison during 4 periods of follow-up (quartile): the first ranging from 1 to 18 months; the second ranging from 19 to 36 months; the third from 37 to 72 months and the fourth >72 months. Cancer-specific and health-related factors were analyzed separately, and the change was determined during follow-up.
  
  
  CONCLUSIONS
  The global QoL, highlighted by validated cancer-specific and health-related questionnaires, is certainly on a satisfactory level. Thus, the education of the patient, the exploration of the pros and cons of an orthotopic neobladder and the active participation in treatment decision seem to be the keys to better improve the post-operative QoL during the follow-up period.
authors.affiliation: Urology Clinic, Catholic University of the Sacred Heart, Rome, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: D''Agostino
authors.forename: Marco
authors.initials: M
authors.lastname: Racioppi
authors.forename: Dario
authors.initials: D
authors.lastname: Pugliese
authors.forename: Mauro
authors.initials: M
authors.lastname: Ragonese
authors.forename: Luca
authors.initials: L
authors.lastname: Di Gianfrancesco
authors.forename: Alessio
authors.initials: A
authors.lastname: Filianoti
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Palermo
authors.forename: Emanuele
authors.initials: E
authors.lastname: Belgrano
authors.forename: Salvatore
authors.initials: S
authors.lastname: Siracusano
authors.forename: Mauro
authors.initials: M
authors.lastname: Niero
authors.forename: Ciro
authors.initials: C
authors.lastname: Imbimbo
authors.forename: Massimo
authors.initials: M
authors.lastname: Iafrate
authors.forename: Walter
authors.initials: W
authors.lastname: Artibani
authors.forename: Maria Angela
authors.initials: MA
authors.lastname: Cerruto
authors.forename: Renato
authors.initials: R
authors.lastname: Talamini
authors.forename: PierFrancesco
authors.initials: P
authors.lastname: Bassi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D015653:Cystectomy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007082:Ileum / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D057566:Self Report; D013997:Time Factors; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D016476:Urinary Reservoirs, Continent