title: Epidemiology of Nonalcoholic Fatty Liver Disease and Nonalcoholic Steatohepatitis in the United States and the Rest of the World.
abstract: Nonalcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease with increasing prevalence, which can progress to cirrhosis and liver failure. Because of the obesity epidemic and increasing prevalence of metabolic syndrome, NAFLD and its progressive form, nonalcoholic steatohepatitis, are seen more commonly in different parts of the world. This article reviews the worldwide epidemiology of NAFLD and nonalcoholic steatohepatitis. The PubMed database was used to identify studies related to epidemiology of NAFLD in the adult population. It is estimated that the epidemic of obesity will continue to fuel the burden of NAFLD and its long-term complications.
authors.affiliation: Betty and Guy Beatty Center for Integrated Research, Inova Fairfax Hospital, Claude Moore Health Education and Research Building, 3300 Gallows Road, Falls Church, VA 22042, USA.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Sayiner
authors.affiliation: Betty and Guy Beatty Center for Integrated Research, Inova Fairfax Hospital, Claude Moore Health Education and Research Building, 3300 Gallows Road, Falls Church, VA 22042, USA.
authors.forename: Aaron
authors.initials: A
authors.lastname: Koenig
authors.affiliation: Betty and Guy Beatty Center for Integrated Research, Inova Fairfax Hospital, Claude Moore Health Education and Research Building, 3300 Gallows Road, Falls Church, VA 22042, USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Henry
authors.affiliation: Betty and Guy Beatty Center for Integrated Research, Inova Fairfax Hospital, Claude Moore Health Education and Research Building, 3300 Gallows Road, Falls Church, VA 22042, USA; Department of Medicine, Center for Liver Diseases, Inova Fairfax Hospital, 300 Gallows Road, Falls Church, VA 22042, USA. Electronic address: zobair.younossi@inova.org.
authors.forename: Zobair M
authors.initials: ZM
authors.lastname: Younossi
mesh_terms: D000349:Africa / Q000453:epidemiology; D001208:Asia / Q000453:epidemiology; D005060:Europe / Q000453:epidemiology; D006801:Humans; D015994:Incidence; D008659:Metabolic Diseases / Q000453:epidemiology; D065626:Non-alcoholic Fatty Liver Disease / Q000453:epidemiology*; D009656:North America / Q000453:epidemiology; D015995:Prevalence; D012307:Risk Factors; D012737:Sex Factors; D013020:South America / Q000453:epidemiology; D014481:United States / Q000453:epidemiology
keywords: Epidemiology; NAFLD; NASH; Prevalence