title: The Rh(ii)-catalyzed formal N-S bond insertion reaction of aryldiazoacetates into N-phenyl-sulfenyl phthalimide.
abstract: The Rh(ii)-catalyzed sulfur ylide [1,2]-rearrangement of carbenoids generated from aryldiazoacetates has been realized via N-S bond insertion, generating tertiary sulfides in moderate to excellent yields. This demonstrates the first use of the sulfur ylide [1,2]-rearrangement undergoing N-S bond insertion. This protocol could proceed smoothly with high regioselectivity, low catalyst loading (0.1 mol% Rh2(OAc)4), gram-scale reaction and broad substrate scope. And the product could be converted into glycine derivatives through simple procedures.
authors.affiliation: Jiangsu Key Laboratory of Drug Discovery for Metabolic Disease and State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjia Xiang, Nanjing 210009, China. hbsun2000@yahoo.com qlxu@cpu.edu.cn.
authors.forename: Zhuang
authors.initials: Z
authors.lastname: Song
authors.forename: Yizhou
authors.initials: Y
authors.lastname: Wu
authors.forename: Tao
authors.initials: T
authors.lastname: Xin
authors.forename: Chao
authors.initials: C
authors.lastname: Jin
authors.forename: Xiaoan
authors.initials: X
authors.lastname: Wen
authors.forename: Hongbin
authors.initials: H
authors.lastname: Sun
authors.forename: Qing-Long
authors.initials: QL
authors.lastname: Xu