title: Rhodium-Catalyzed Intramolecular C-H Silylation by Silacyclobutanes.
abstract: Silacyclobutane was discovered to be an efficient C-H bond silylation reagent. Under the catalysis of Rh(I) /TMS-segphos, silacyclobutane undergoes sequential C-Si/C-H bond activations, affording a series of π-conjugated siloles in high yields and regioselectivities. The catalytic cycle was proposed to involve a rarely documented endocyclic β-hydride elimination of five-membered metallacycles, which after reductive elimination gave rise to a Si-Rh(I) species that is capable of C-H activation.
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.
authors.forename: Qing-Wei
authors.initials: QW
authors.lastname: Zhang
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.
authors.forename: Kun
authors.initials: K
authors.lastname: An
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.
authors.forename: Li-Chuan
authors.initials: LC
authors.lastname: Liu
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.
authors.forename: Shuangxi
authors.initials: S
authors.lastname: Guo
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.
authors.forename: Chenran
authors.initials: C
authors.lastname: Jiang
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China.
authors.forename: Huifang
authors.initials: H
authors.lastname: Guo
authors.affiliation: School of Pharmaceutical Sciences, Tsinghua University, Beijing, 100084, China. whe@mail.tsinghua.edu.cn.
authors.forename: Wei
authors.identifier: 0000-0001-8167-9155
authors.initials: W
authors.lastname: He
keywords: C−H activation; metallocycle; silole; silylation; β-hydrogen elimination