title: Allergic Rhinitis: Environmental Determinants.
abstract: The increasing prevalence of allergic rhinitis (AR) seems to be linked to several important environmental factors that interact with underlying genetic predisposition to influence the risk of this disease. This article examines these environmental determinants of AR, and the evidence for their association with disease prevalence. Exposure to a variety of aeroallergens is strongly implicated in the pathogenesis and progression of AR. Other environmental exposures have been suggested to play potential roles in the risk of AR, including bacterial exposure, air pollution, and environmental toxicants.
authors.affiliation: Division of Emergency Medicine, Children's National Health System, 111 Michigan Avenue NW, Washington, DC 20010, USA.
authors.forename: Joan
authors.initials: J
authors.lastname: Dunlop
authors.affiliation: Division of Pediatric Allergy and Immunology, Johns Hopkins School of Medicine, 600 N. Wolfe Street, CMSC 1102, Baltimore, MD 21287, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Matsui
authors.affiliation: Division of Allergy and Immunology, Children's National Health System, George Washington University School of Medicine and Health Sciences, 111 Michigan Avenue, Northwest, Suite W-100A, Washington, DC 20010, USA. Electronic address: hsharma@childrensnational.org.
authors.forename: Hemant P
authors.initials: HP
authors.lastname: Sharma
mesh_terms: D000397:Air Pollution / Q000009:adverse effects; D004781:Environmental Exposure / Q000009:adverse effects*; D006801:Humans; D065631:Rhinitis, Allergic / Q000209:etiology*; D012307:Risk Factors
keywords: Allergen; Allergic rhinitis; Environment; Risk; Sensitization