title: Adaptation and validation of the Spanish version of the Actinic Keratosis Quality of Life questionnaire.
abstract: OBJECTIVE
  While there are questionnaires for evaluating the effects of skin cancer on patient quality of life, there are no specific questionnaires available in Spanish for evaluating quality of life in patients with actinic keratosis. The aim of this study was to translate and culturally adapt the Actinic Keratosis Quality of Life (AKQoL) questionnaire into Spanish.
  
  
  METHODS
  The original questionnaire was translated into Spanish following the guidelines for the cross-cultural adaptation of self-report measures. Several measures of general reliability and validity were calculated, including Cronbach α for internal consistency and the Spearman rank-order correlation coefficient and a Bland-Altman plot for test-retest reliability. To test concurrent validity, we used the Pearson correlation coefficient to measure the correlation between AKQoL and Skindex-29 scores.
  
  
  RESULTS
  The final version of the questionnaire was administered to 621 patients with actinic keratosis, who scored a mean (SD) of 5.25 (4.73) points (total possible score, 0-25). The Cronbach α reliability coefficient analysis was 0.84. The correlation between the mean (SD) score on the Skindex-29 (1.87 [4.07]) and on the AKQoL (1.97 [2.98] was 0.344 (P=.002, Spearman's rho), with a proportion of shared variance of 11.8%.
  
  
  CONCLUSIONS
  The translation, cross-cultural adaptation, and validation of the original AKQoL produced a reliable, easily understandable questionnaire for evaluating the impact of actinic keratosis on the quality of life of patients in our setting.
authors.affiliation: Servicio de Dermatología, Hospital Central de la Defensa Gómez Ulla, Madrid, España.
authors.forename: Isabel
authors.initials: I
authors.lastname: Longo Imedio
authors.affiliation: Servicio de Dermatolgía, Instituto Valenciano de Oncología, Valencia, España. Electronic address: cserraguillen@gmail.com.
authors.forename: Carlos
authors.initials: C
authors.lastname: Serra-Guillén
mesh_terms: D000368:Aged; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D055623:Keratosis, Actinic / Q000175:diagnosis*; D007802:Language; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D014177:Translations
keywords: Actinic keratosis; Calidad de vida; Español; Estudio de validación; Quality of life; Queratosis actínica; Spanish; Validation study