title: Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma.
abstract: Primary angle closure glaucoma (PACG) is a major cause of blindness worldwide. We conducted a genome-wide association study (GWAS) followed by replication in a combined total of 10,503 PACG cases and 29,567 controls drawn from 24 countries across Asia, Australia, Europe, North America, and South America. We observed significant evidence of disease association at five new genetic loci upon meta-analysis of all patient collections. These loci are at EPDR1 rs3816415 (odds ratio (OR) = 1.24, P = 5.94 × 10(-15)), CHAT rs1258267 (OR = 1.22, P = 2.85 × 10(-16)), GLIS3 rs736893 (OR = 1.18, P = 1.43 × 10(-14)), FERMT2 rs7494379 (OR = 1.14, P = 3.43 × 10(-11)), and DPM2-FAM102A rs3739821 (OR = 1.15, P = 8.32 × 10(-12)). We also confirmed significant association at three previously described loci (P < 5 × 10(-8) for each sentinel SNP at PLEKHA7, COL11A1, and PCMTD1-ST18), providing new insights into the biology of PACG.
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.|Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Department of Biochemistry, National University of Singapore, Singapore.
authors.forename: Chiea Chuen
authors.initials: CC
authors.lastname: Khor
authors.affiliation: Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
authors.forename: Tan
authors.initials: T
authors.lastname: Do
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Jia
authors.affiliation: Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Masakazu
authors.initials: M
authors.lastname: Nakano
authors.affiliation: Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.
authors.forename: Ronnie
authors.identifier: http://orcid.org/0000-0001-7368-0252
authors.initials: R
authors.lastname: George
authors.affiliation: Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.|Department of Ophthalmology, College of Medicine, University of Florida, Jacksonville, Florida, USA.
authors.forename: Khaled
authors.initials: K
authors.lastname: Abu-Amero
authors.affiliation: Department of Genetics, Aravind Medical Research Foundation, Madurai, India.
authors.forename: Roopam
authors.initials: R
authors.lastname: Duvesh
authors.affiliation: Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Li Jia
authors.initials: LJ
authors.lastname: Chen
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Zheng
authors.identifier: http://orcid.org/0000-0002-7060-2213
authors.initials: Z
authors.lastname: Li
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Monisha E
authors.initials: ME
authors.lastname: Nongpiur
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Shamira A
authors.initials: SA
authors.lastname: Perera
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Qiao
authors.affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.
authors.forename: Hon-Tym
authors.initials: HT
authors.lastname: Wong
authors.affiliation: Department of Ophthalmology, University of the Ryukyus, Okinawa, Nishihara, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Sakai
authors.affiliation: Center of Molecular Biology and Genetic Engineering, University of Campinas, Campinas, Brazil.
authors.forename: Mônica
authors.initials: M
authors.lastname: Barbosa de Melo
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Mei-Chin
authors.initials: MC
authors.lastname: Lee
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Anita S
authors.initials: AS
authors.lastname: Chan
authors.affiliation: Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia and Hospital Universiti Sains Malaysia, Kelantan, Malaysia.
authors.forename: Yaakub
authors.initials: Y
authors.lastname: Azhany
authors.affiliation: Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
authors.forename: Thi Lam Huong
authors.initials: TL
authors.lastname: Dao
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Ikeda
authors.affiliation: Instituto de Glaucoma y Catarata, Lima, Peru.
authors.forename: Rodolfo A
authors.initials: RA
authors.lastname: Perez-Grossmann
authors.affiliation: Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Zarnowski
authors.affiliation: NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.|Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.|Division of Genetics, UCL Institute of Ophthalmology, London, UK.
authors.forename: Alexander C
authors.identifier: http://orcid.org/0000-0002-2099-8870
authors.initials: AC
authors.lastname: Day
authors.affiliation: Department of Ophthalmology, Medical Faculty Mannheim of the Ruprecht Karls University Heidelberg, Heidelberg, Germany.
authors.forename: Jost B
authors.initials: JB
authors.lastname: Jonas
authors.affiliation: Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Pancy O S
authors.initials: PO
authors.lastname: Tam
authors.affiliation: Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.
authors.forename: Tuan Anh
authors.initials: TA
authors.lastname: Tran
authors.affiliation: Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.
authors.forename: Humaira
authors.initials: H
authors.lastname: Ayub
authors.affiliation: Pakistan Institute of Ophthalmology, Al-Shifa Trust Eye Hospital, Rawalpindi, Pakistan.
authors.forename: Farah
authors.initials: F
authors.lastname: Akhtar
authors.affiliation: Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands.
authors.forename: Shazia
authors.initials: S
authors.lastname: Micheal
authors.affiliation: Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Paul T K
authors.initials: PT
authors.lastname: Chew
authors.affiliation: King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: Leyla A
authors.initials: LA
authors.lastname: Aljasim
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Tanuj
authors.initials: T
authors.lastname: Dada
authors.affiliation: Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.
authors.forename: Tam Thi
authors.initials: TT
authors.lastname: Luu
authors.affiliation: Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.
authors.forename: Mona S
authors.initials: MS
authors.lastname: Awadalla
authors.affiliation: Department of Ophthalmology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Naris
authors.initials: N
authors.lastname: Kitnarong
authors.affiliation: Glaucoma Services, Department of Ophthalmology, Rajavithi Hospital, Bangkok, Thailand.|College of Medicine, Rangsit University, Bangkok, Thailand.
authors.forename: Boonsong
authors.initials: B
authors.lastname: Wanichwecharungruang
authors.affiliation: Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.
authors.forename: Yee Yee
authors.initials: YY
authors.lastname: Aung
authors.affiliation: Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
authors.forename: Jelinar
authors.initials: J
authors.lastname: Mohamed-Noor
authors.affiliation: Department of Genetics, Aravind Medical Research Foundation, Madurai, India.
authors.forename: Saravanan
authors.initials: S
authors.lastname: Vijayan
authors.affiliation: Vision Research Foundation, Sankara Nethralaya, Chennai, India.
authors.forename: Sripriya
authors.initials: S
authors.lastname: Sarangapani
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Division of Ophthalmology, Changi General Hospital, Singapore.
authors.forename: Rahat
authors.initials: R
authors.lastname: Husain
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Division of Ophthalmology, Changi General Hospital, Singapore.
authors.forename: Aliza
authors.initials: A
authors.lastname: Jap
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Mani
authors.initials: M
authors.lastname: Baskaran
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: David
authors.initials: D
authors.lastname: Goh
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Daniel H
authors.initials: DH
authors.lastname: Su
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.
authors.forename: Huaizhou
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.
authors.forename: Vernon K
authors.initials: VK
authors.lastname: Yong
authors.affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.
authors.forename: Leonard W
authors.initials: LW
authors.lastname: Yip
authors.affiliation: Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.
authors.forename: Tuyet Bach
authors.initials: TB
authors.lastname: Trinh
authors.affiliation: Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.
authors.forename: Manchima
authors.initials: M
authors.lastname: Makornwattana
authors.affiliation: Eye Department, Viet Tiep General Hospital, Hai Phong, Vietnam.
authors.forename: Thanh Thu
authors.initials: TT
authors.lastname: Nguyen
authors.affiliation: Asian Eye Institute, Manila, Philippines.|Division of Ophthalmology, University of the East, Manila, Philippines.
authors.forename: Edgar U
authors.initials: EU
authors.lastname: Leuenberger
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: Ki-Ho
authors.initials: KH
authors.lastname: Park
authors.affiliation: Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.|Faculty of Medicine, University of Indonesia, Jakarta, Indonesia.
authors.forename: Widya Artini
authors.initials: WA
authors.lastname: Wiyogo
authors.affiliation: Narayana Nethralaya Eye Hospital, Bangalore, India.
authors.forename: Rajesh S
authors.initials: RS
authors.lastname: Kumar
authors.affiliation: Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.
authors.forename: Celso
authors.initials: C
authors.lastname: Tello
authors.affiliation: Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Kurimoto
authors.affiliation: Nepal Glaucoma Eye Clinic, Tilganga Institute of Ophthalmology, Kathmandu, Nepal.
authors.forename: Suman S
authors.initials: SS
authors.lastname: Thapa
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.
authors.forename: Kessara
authors.initials: K
authors.lastname: Pathanapitoon
authors.affiliation: Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
authors.forename: John F
authors.initials: JF
authors.lastname: Salmon
authors.affiliation: Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.
authors.forename: Yong Ho
authors.initials: YH
authors.lastname: Sohn
authors.affiliation: Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Fea
authors.affiliation: Ozaki Eye Hospital, Hyuga, Japan.|Department of Ophthalmology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
authors.forename: Mineo
authors.initials: M
authors.lastname: Ozaki
authors.affiliation: Department of Ophthalmology, University of Hong Kong, Hong Kong, China.
authors.forename: Jimmy S M
authors.initials: JS
authors.lastname: Lai
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Visanee
authors.initials: V
authors.lastname: Tantisevi
authors.affiliation: Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.
authors.forename: Chaw Chaw
authors.initials: CC
authors.lastname: Khaing
authors.affiliation: Mizoguchi Eye Hospital, Sasebo, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Mizoguchi
authors.affiliation: Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.
authors.forename: Satoko
authors.initials: S
authors.lastname: Nakano
authors.affiliation: Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Chan-Yun
authors.initials: CY
authors.lastname: Kim
authors.affiliation: Shijiazhuang First Eye Hospital, Shijiazhuang, China.
authors.forename: Guangxian
authors.initials: G
authors.lastname: Tang
authors.affiliation: Handan Eye Hospital, Handan, China.
authors.forename: Sujie
authors.initials: S
authors.lastname: Fan
authors.affiliation: Eye Institute and Affiliated Xiamen Eye Center, Xiamen University, Fujian Provincial Key Laboratory of Ophthalmology and Visual Science, Xiamen, China.
authors.forename: Renyi
authors.initials: R
authors.lastname: Wu
authors.affiliation: Anyang Eye Hospital, Anyang, China.
authors.forename: Hailin
authors.initials: H
authors.lastname: Meng
authors.affiliation: Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
authors.forename: Thi Thuy Giang
authors.initials: TT
authors.lastname: Nguyen
authors.affiliation: Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
authors.forename: Tien Dat
authors.initials: TD
authors.lastname: Tran
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Morio
authors.initials: M
authors.lastname: Ueno
authors.affiliation: Department of Ophthalmology, Pasig City General Hospital, Pasig City, Philippines.
authors.forename: Jose Maria
authors.initials: JM
authors.lastname: Martinez
authors.affiliation: University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.|Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Norlina
authors.initials: N
authors.lastname: Ramli
authors.affiliation: Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.|Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.
authors.forename: Yin Mon
authors.initials: YM
authors.lastname: Aung
authors.affiliation: Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.|Binan Doctors Eye Center, Binan Doctors Hospital, Laguna, Philippines.
authors.forename: Rigo Daniel
authors.initials: RD
authors.lastname: Reyes
authors.affiliation: Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.|BMI Park Hospital Nottingham, Nottingham, UK.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Vernon
authors.affiliation: International Specialist Eye Centre, Kuala Lumpur, Malaysia.
authors.forename: Seng Kheong
authors.initials: SK
authors.lastname: Fang
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Zhicheng
authors.initials: Z
authors.lastname: Xie
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Xiao Yin
authors.initials: XY
authors.lastname: Chen
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Jia Nee
authors.identifier: http://orcid.org/0000-0001-9899-2308
authors.initials: JN
authors.lastname: Foo
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Kar Seng
authors.identifier: http://orcid.org/0000-0002-3822-7759
authors.initials: KS
authors.lastname: Sim
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Tina T
authors.initials: TT
authors.lastname: Wong
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Desmond T
authors.initials: DT
authors.lastname: Quek
authors.affiliation: Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.
authors.forename: Rengaraj
authors.initials: R
authors.lastname: Venkatesh
authors.affiliation: Glaucoma Clinic, Aravind Eye Hospital, Pondicherry, India.
authors.forename: Srinivasan
authors.initials: S
authors.lastname: Kavitha
authors.affiliation: Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.
authors.forename: Subbiah R
authors.initials: SR
authors.lastname: Krishnadas
authors.affiliation: Vision Research Foundation, Sankara Nethralaya, Chennai, India.
authors.forename: Nagaswamy
authors.initials: N
authors.lastname: Soumittra
authors.affiliation: Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.
authors.forename: Balekudaru
authors.initials: B
authors.lastname: Shantha
authors.affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.
authors.forename: Boon-Ang
authors.initials: BA
authors.lastname: Lim
authors.affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.
authors.forename: Jeanne
authors.initials: J
authors.lastname: Ogle
authors.affiliation: Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.
authors.forename: José P C
authors.initials: JP
authors.lastname: de Vasconcellos
authors.affiliation: Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.
authors.forename: Vital P
authors.initials: VP
authors.lastname: Costa
authors.affiliation: Glaucoma Clinic, Aravind Eye Hospital, Madurai, India.
authors.forename: Ricardo Y
authors.initials: RY
authors.lastname: Abe
authors.affiliation: Center of Molecular Biology and Genetic Engineering, University of Campinas, Campinas, Brazil.
authors.forename: Bruno B
authors.initials: BB
authors.lastname: de Souza
authors.affiliation: Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Chelvin C
authors.initials: CC
authors.lastname: Sng
authors.affiliation: Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Maria C
authors.initials: MC
authors.lastname: Aquino
authors.affiliation: Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Kosior-Jarecka
authors.affiliation: Instituto de Ciencias Médicas, Lima, Peru.
authors.forename: Guillermo Barreto
authors.initials: GB
authors.lastname: Fong
authors.affiliation: Hospital Nacional Arzobispo Loayza, Lima, Peru.
authors.forename: Vania Castro
authors.initials: VC
authors.lastname: Tamanaja
authors.affiliation: Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima, Peru.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Fujita
authors.affiliation: NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.|Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.|Division of Genetics, UCL Institute of Ophthalmology, London, UK.
authors.forename: Yuzhen
authors.initials: Y
authors.lastname: Jiang
authors.affiliation: NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.|Division of Genetics, UCL Institute of Ophthalmology, London, UK.
authors.forename: Naushin
authors.initials: N
authors.lastname: Waseem
authors.affiliation: NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.|Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.|Division of Genetics, UCL Institute of Ophthalmology, London, UK.
authors.forename: Sancy
authors.initials: S
authors.lastname: Low
authors.affiliation: Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.
authors.forename: Huan Nguyen
authors.initials: HN
authors.lastname: Pham
authors.affiliation: King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
authors.forename: Sami
authors.initials: S
authors.lastname: Al-Shahwan
authors.affiliation: King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.|Wilmer Eye Institute, Johns Hopkins Hospital School of Medicine, Baltimore, Maryland, USA.
authors.forename: E Randy
authors.initials: ER
authors.lastname: Craven
authors.affiliation: Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.
authors.forename: Muhammad Imran
authors.initials: MI
authors.lastname: Khan
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Rrima
authors.initials: R
authors.lastname: Dada
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Kuldeep
authors.initials: K
authors.lastname: Mohanty
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Muneeb A
authors.initials: MA
authors.lastname: Faiq
authors.affiliation: Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.|Centre for Eye Research Australia, University of Melbourne, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.
authors.forename: Alex W
authors.initials: AW
authors.lastname: Hewitt
authors.affiliation: Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.|Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.
authors.forename: Kathryn P
authors.identifier: http://orcid.org/0000-0001-8217-1249
authors.initials: KP
authors.lastname: Burdon
authors.affiliation: Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
authors.forename: Eng Hui
authors.initials: EH
authors.lastname: Gan
authors.affiliation: Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.
authors.forename: Anuwat
authors.initials: A
authors.lastname: Prutthipongsit
authors.affiliation: Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.
authors.forename: Thipnapa
authors.initials: T
authors.lastname: Patthanathamrongkasem
authors.affiliation: Asian Eye Institute, Manila, Philippines.
authors.forename: Mary Ann T
authors.initials: MA
authors.lastname: Catacutan
authors.affiliation: Asian Eye Institute, Manila, Philippines.
authors.forename: Irene R
authors.initials: IR
authors.lastname: Felarca
authors.affiliation: Asian Eye Institute, Manila, Philippines.
authors.forename: Chona S
authors.initials: CS
authors.lastname: Liao
authors.affiliation: Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.
authors.forename: Emma
authors.initials: E
authors.lastname: Rusmayani
authors.affiliation: Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.
authors.forename: Vira Wardhana
authors.initials: VW
authors.lastname: Istiantoro
authors.affiliation: Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Consolandi
authors.affiliation: Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.
authors.forename: Giulia
authors.initials: G
authors.lastname: Pignata
authors.affiliation: Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Lavia
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Prin
authors.initials: P
authors.lastname: Rojanapongpun
authors.affiliation: Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
authors.forename: Lerprat
authors.initials: L
authors.lastname: Mangkornkanokpong
authors.affiliation: Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
authors.forename: Sunee
authors.initials: S
authors.lastname: Chansangpetch
authors.affiliation: Department of Ophthalmology, Queen Mary Hospital, Hong Kong, China.
authors.forename: Jonathan C H
authors.initials: JC
authors.lastname: Chan
authors.affiliation: Department of Ophthalmology, University of Hong Kong, Hong Kong, China.
authors.forename: Bonnie N K
authors.initials: BN
authors.lastname: Choy
authors.affiliation: Department of Ophthalmology, University of Hong Kong, Hong Kong, China.
authors.forename: Jennifer W H
authors.initials: JW
authors.lastname: Shum
authors.affiliation: Department of Ophthalmology, North Okkalarpa General Hospital, Yangon, Myanmar.
authors.forename: Hlaing May
authors.initials: HM
authors.lastname: Than
authors.affiliation: Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.|Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.
authors.forename: Khin Thida
authors.initials: KT
authors.lastname: Oo
authors.affiliation: Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.|Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.
authors.forename: Aye Thi
authors.initials: AT
authors.lastname: Han
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Victor H
authors.initials: VH
authors.lastname: Yong
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Xiao-Yu
authors.initials: XY
authors.lastname: Ng
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Shuang Ru
authors.initials: SR
authors.lastname: Goh
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Yaan Fun
authors.initials: YF
authors.lastname: Chong
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Martin L
authors.initials: ML
authors.lastname: Hibberd
authors.affiliation: Institute for Human Genetics, University of California, San Francisco, San Francisco, California, USA.
authors.forename: Mark
authors.identifier: http://orcid.org/0000-0001-5783-1401
authors.initials: M
authors.lastname: Seielstad
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.
authors.forename: Eileen
authors.initials: E
authors.lastname: Png
authors.affiliation: Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.|Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: Sarah J
authors.identifier: http://orcid.org/0000-0001-7873-933X
authors.initials: SJ
authors.lastname: Dunstan
authors.affiliation: Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam.
authors.forename: Nguyen Van Vinh
authors.initials: NV
authors.lastname: Chau
authors.affiliation: Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.|Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China.
authors.forename: Jinxin
authors.initials: J
authors.lastname: Bei
authors.affiliation: Sun Yat-Sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China.|Department of Experimental Research, Sun Yat-sen University Cancer Center, Guangzhou, China.|Peking Union Medical College, Beijing, China.
authors.forename: Yi Xin
authors.initials: YX
authors.lastname: Zeng
authors.affiliation: Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.
authors.forename: Abhilasha
authors.initials: A
authors.lastname: Karkey
authors.affiliation: Oxford University Clinical Research Unit-Nepal, Patan Academy of Health Sciences, Patan Hospital, Patan, Nepal.
authors.forename: Buddha
authors.initials: B
authors.lastname: Basnyat
authors.affiliation: Institute of Human Genetics, Friedrich Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
authors.forename: Francesca
authors.initials: F
authors.lastname: Pasutto
authors.affiliation: Department of Ophthalmology, Monfalcone Hospital, Gorizia, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Paoli
authors.affiliation: Department of Surgery, Section of Ophthalmology, University of Siena, Siena, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Frezzotti
authors.affiliation: Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Jie Jin
authors.initials: JJ
authors.lastname: Wang
authors.affiliation: Centre for Vision Research, Department of Ophthalmology, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: Mitchell
authors.affiliation: Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA.|Wynn Institute for Vision Research, University of Iowa, Iowa City, Iowa, USA.
authors.forename: John H
authors.initials: JH
authors.lastname: Fingert
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina, USA.
authors.forename: R Rand
authors.initials: RR
authors.lastname: Allingham
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Department of Ophthalmology, Duke University Eye Center, Durham, North Carolina, USA.|Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA.
authors.forename: Michael A
authors.identifier: http://orcid.org/0000-0003-2667-5420
authors.initials: MA
authors.lastname: Hauser
authors.affiliation: Division of Medical Oncology, National Cancer Centre, Singapore.
authors.forename: Soon Thye
authors.initials: ST
authors.lastname: Lim
authors.affiliation: Department of Economics, National University of Singapore, Singapore.
authors.forename: Soo Hong
authors.initials: SH
authors.lastname: Chew
authors.affiliation: Department of Psychology, National University of Singapore, Singapore.
authors.forename: Richard P
authors.initials: RP
authors.lastname: Ebstein
authors.affiliation: Institut Pasteur, Functional Genetics of Infectious Diseases Unit, Department of Genomes and Genetics, Paris, France.|Centre National de la Recherche Scientifique, Unité de Recherche Associée 3012, Paris, France.
authors.forename: Anavaj
authors.initials: A
authors.lastname: Sakuntabhai
authors.affiliation: Department of Ophthalmology, Seoul National University Bundang Hospital, Gyeonggi, Republic of Korea.
authors.forename: Kyu Hyung
authors.initials: KH
authors.lastname: Park
authors.affiliation: Department of Ophthalmology, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Republic of Korea.
authors.forename: Jeeyun
authors.initials: J
authors.lastname: Ahn
authors.affiliation: Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.
authors.forename: Greet
authors.initials: G
authors.lastname: Boland
authors.affiliation: Department of Medical Microbiology and Virology, University Medical Center Utrecht, Utrecht, the Netherlands.
authors.forename: Harm
authors.initials: H
authors.lastname: Snippe
authors.affiliation: Department of Ophthalmology, University Hospital Nottingham, University of Nottingham, Nottingham, UK.
authors.forename: Richard
authors.initials: R
authors.lastname: Stead
authors.affiliation: Department of Ophthalmology/Glaucoma Section, Asian Hospital and Medical Center, Muntinlupa City, Philippines.
authors.forename: Raquel
authors.initials: R
authors.lastname: Quino
authors.affiliation: Myanmar Eye Centre, Pun Hlaing Silom Hospital, Yangon, Myanmar.|Myanmar Eye Centre, Shwe La Min Hospital, Yangon, Myanmar.
authors.forename: Su Nyunt
authors.initials: SN
authors.lastname: Zaw
authors.affiliation: Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin, Poland.
authors.forename: Urszula
authors.initials: U
authors.lastname: Lukasik
authors.affiliation: Narayana Nethralaya Eye Hospital, Bangalore, India.
authors.forename: Rohit
authors.initials: R
authors.lastname: Shetty
authors.affiliation: University of Malaya, Eye Research Centre, Kuala Lumpur, Malaysia.|Department of Ophthalmology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
authors.forename: Mimiwati
authors.initials: M
authors.lastname: Zahari
authors.affiliation: Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Republic of Korea.
authors.forename: Hyoung Won
authors.initials: HW
authors.lastname: Bae
authors.affiliation: Department of Ophthalmology, No. 1 Defence Services General Hospital, Yangon, Myanmar.
authors.forename: Nay Lin
authors.initials: NL
authors.lastname: Oo
authors.affiliation: Department of Ophthalmology, Oita University Faculty of Medicine, Oita, Japan.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Kubota
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
authors.forename: Anita
authors.initials: A
authors.lastname: Manassakorn
authors.affiliation: Department of Ophthalmology, King Chulalongkorn Memorial Hospital, Bangkok, Thailand.
authors.forename: Wing Lau
authors.initials: WL
authors.lastname: Ho
authors.affiliation: Dipartimento di Scienze Chirurgiche, Università di Torino, Turin, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Dallorto
authors.affiliation: Department of Ophthalmology, Konyang University, Kim's Eye Hospital, Myung-Gok Eye Research Institute, Seoul, Republic of Korea.
authors.forename: Young Hoon
authors.initials: YH
authors.lastname: Hwang
authors.affiliation: Oxford Eye Hospital, John Radcliffe Hospital, Oxford University Hospitals NHS Trust, Oxford, UK.
authors.forename: Christine A
authors.initials: CA
authors.lastname: Kiire
authors.affiliation: Department of Ophthalmology, Kobe City Medical Center General Hospital, Kobe, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Kuroda
authors.affiliation: Glaucoma Service Jakarta Eye Center, Jakarta, Indonesia.
authors.forename: Zeiras Eka
authors.initials: ZE
authors.lastname: Djamal
authors.affiliation: Asian Eye Institute, Manila, Philippines.
authors.forename: Jovell Ian M
authors.initials: JI
authors.lastname: Peregrino
authors.affiliation: Narayana Nethralaya Eye Hospital, Bangalore, India.|GROW Research Laboratory, Narayana Nethralaya Foundation, Bangalore, India.
authors.forename: Arkasubhra
authors.initials: A
authors.lastname: Ghosh
authors.affiliation: Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Republic of Korea.
authors.forename: Jin Wook
authors.initials: JW
authors.lastname: Jeoung
authors.affiliation: Eye Department, Viet Tiep General Hospital, Hai Phong, Vietnam.
authors.forename: Tung S
authors.initials: TS
authors.lastname: Hoan
authors.affiliation: Department of Ophthalmology, Thammasat University Faculty of Medicine, Rangsit, Thailand.
authors.forename: Nuttamon
authors.initials: N
authors.lastname: Srisamran
authors.affiliation: Department of Ophthalmology, Hospital Kuala Lumpur, Kuala Lumpur, Malaysia.
authors.forename: Thayanithi
authors.initials: T
authors.lastname: Sandragasu
authors.affiliation: Mandalay Eye Department, Mandalay Eye ENT Hospital, University of Medicine Mandalay, Mandalay, Myanmar.
authors.forename: Saw Htoo
authors.initials: SH
authors.lastname: Set
authors.affiliation: Department of Glaucoma, Da Nang Eye Hospital, Da Nang City, Vietnam.
authors.forename: Vi Huyen
authors.initials: VH
authors.lastname: Doan
authors.affiliation: Division of Genetics, UCL Institute of Ophthalmology, London, UK.
authors.forename: Shomi S
authors.initials: SS
authors.lastname: Bhattacharya
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Ching-Lin
authors.initials: CL
authors.lastname: Ho
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Donald T
authors.initials: DT
authors.lastname: Tan
authors.affiliation: All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Ramanjit
authors.initials: R
authors.lastname: Sihota
authors.affiliation: Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Seng-Chee
authors.initials: SC
authors.lastname: Loon
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Kazuhiko
authors.initials: K
authors.lastname: Mori
authors.affiliation: Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kinoshita
authors.affiliation: Department of Ophthalmology, Radboud University Medical Centre, Nijmegen, the Netherlands.|Department of Human Genetics, Radboud University Medical Centre, Nijmegen, the Netherlands.
authors.forename: Anneke I den
authors.initials: AI
authors.lastname: Hollander
authors.affiliation: Department of Biosciences, COMSATS Institute of Information Technology, Islamabad, Pakistan.|Department of Biochemistry, Al-Nafees Medical College and Hospital, Isra University, Islamabad, Pakistan.
authors.forename: Raheel
authors.initials: R
authors.lastname: Qamar
authors.affiliation: Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Ya-Xing
authors.initials: YX
authors.lastname: Wang
authors.affiliation: Genome Institute of Singapore, A-STAR, Singapore.|Saw Swee Hock School of Public Health, National University of Singapore, Singapore.|Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.|Saw Swee Hock School of Public Health, National University of Singapore, Singapore.|Life Sciences Institute, National University of Singapore, Singapore.|National University of Singapore Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore.|Department of Statistics and Applied Probability, National University of Singapore, Singapore.
authors.forename: Yik Y
authors.initials: YY
authors.lastname: Teo
authors.affiliation: Saw Swee Hock School of Public Health, National University of Singapore, Singapore.|Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: E-Shyong
authors.initials: ES
authors.lastname: Tai
authors.affiliation: Department of Glaucoma, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.
authors.forename: Curt
authors.initials: C
authors.lastname: Hartleben-Matkin
authors.affiliation: Department of Genetics, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.
authors.forename: David
authors.initials: D
authors.lastname: Lozano-Giral
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Saw Swee Hock School of Public Health, National University of Singapore, Singapore.
authors.forename: Seang Mei
authors.initials: SM
authors.lastname: Saw
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Ching-Yu
authors.initials: CY
authors.lastname: Cheng
authors.affiliation: Department of Genetics, Institute of Ophthalmology 'Conde de Valenciana', Mexico City, Mexico.|Department of Biochemistry, Faculty of Medicine, Universidad Nacional Autónoma de México, Mexico City, Mexico.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Zenteno
authors.affiliation: Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Chi Pui
authors.initials: CP
authors.lastname: Pang
authors.affiliation: Ho Chi Minh City Eye Hospital, Ho Chi Minh City, Vietnam.
authors.forename: Huong T T
authors.initials: HT
authors.lastname: Bui
authors.affiliation: Department of Ophthalmology, Tan Tock Seng Hospital, NHG Eye Institute, Singapore.
authors.forename: Owen
authors.initials: O
authors.lastname: Hee
authors.affiliation: Department of Ophthalmology, Flinders University, Flinders Medical Centre, Adelaide, South Australia, Australia.
authors.forename: Jamie E
authors.initials: JE
authors.lastname: Craig
authors.affiliation: King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.|Wilmer Eye Institute, Johns Hopkins Hospital School of Medicine, Baltimore, Maryland, USA.
authors.forename: Deepak P
authors.initials: DP
authors.lastname: Edward
authors.affiliation: Department of Ophthalmology, University of the Ryukyus, Okinawa, Nishihara, Japan.
authors.forename: Michiko
authors.initials: M
authors.lastname: Yonahara
authors.affiliation: Department of Ophthalmology, Faculty of Medical Sciences, University of Campinas, Campinas, Brazil.
authors.forename: Jamil Miguel
authors.initials: JM
authors.lastname: Neto
authors.affiliation: Centro de Genética y Biología Molecular, Universidad de San Martín de Porres, Lima, Peru.
authors.forename: Maria L
authors.initials: ML
authors.lastname: Guevara-Fujita
authors.affiliation: Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Xu
authors.affiliation: Einhorn Clinical Research Center, New York Eye and Ear Infirmary of Mount Sinai, New York, New York, USA.
authors.forename: Robert
authors.identifier: http://orcid.org/0000-0002-9368-7547
authors.initials: R
authors.lastname: Ritch
authors.affiliation: Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia and Hospital Universiti Sains Malaysia, Kelantan, Malaysia.
authors.forename: Ahmad Tajudin
authors.initials: AT
authors.lastname: Liza-Sharmini
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Tien Y
authors.initials: TY
authors.lastname: Wong
authors.affiliation: Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
authors.forename: Saleh
authors.initials: S
authors.lastname: Al-Obeidan
authors.affiliation: Vietnam National Institute of Ophthalmology, Hanoi, Vietnam.
authors.forename: Nhu Hon
authors.initials: NH
authors.lastname: Do
authors.affiliation: Department of Genetics, Aravind Medical Research Foundation, Madurai, India.
authors.forename: Periasamy
authors.initials: P
authors.lastname: Sundaresan
authors.affiliation: Department of Ophthalmology and Visual Sciences, Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Clement C
authors.initials: CC
authors.lastname: Tham
authors.affiliation: NIHR Biomedical Research Centre for Ophthalmology at Moorfields Eye Hospital and University College London Institute of Ophthalmology, London, UK.|Glaucoma Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.|Division of Genetics, UCL Institute of Ophthalmology, London, UK.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Foster
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Jadhavbhai Nathamal Singhvi Department of Glaucoma, Medical Research Foundation, Sankara Nethralaya, Chennai, India.
authors.forename: Lingam
authors.initials: L
authors.lastname: Vijaya
authors.affiliation: Department of Genomic Medical Sciences, Kyoto Prefectural University of Medicine, Kyoto, Japan.
authors.forename: Kei
authors.initials: K
authors.lastname: Tashiro
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.
authors.forename: Eranga N
authors.initials: EN
authors.lastname: Vithana
authors.affiliation: Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology and Visual Science Key Laboratory, Beijing, China.|Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
authors.forename: Ningli
authors.initials: N
authors.lastname: Wang
authors.affiliation: Singapore Eye Research Institute, Singapore National Eye Centre and Eye ACP, Duke-National University of Singapore, Singapore.|Department of Ophthalmology, National University Health System, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.
authors.forename: Tin
authors.initials: T
authors.lastname: Aung
mesh_terms: D002460:Cell Line; D002874:Chromosome Mapping; D005260:Female; D015870:Gene Expression; D056426:Genetic Loci; D020022:Genetic Predisposition to Disease; D055106:Genome-Wide Association Study; D005838:Genotype; D015812:Glaucoma, Angle-Closure / Q000235:genetics*; D006801:Humans; D008297:Male