title: Onychomycosis and its Chemotherapy.
abstract: Onychomycosis (fungal nail infections) is very common worldwide but is fortunately not often lethal. Several powerful drugs have been introduced into clinical practice in recent years, but these infections remain difficult to cure primarily due to the difficulty of penetration of drug to the site of the infection in therapeutic concentrations. The nature of the disease, the causative fungi, and the characteristics of the drugs employed to treat this condition are discussed in this review.
authors.forename: Anwer
authors.initials: A
authors.lastname: Basha
authors.affiliation: HEJ Research Institute of chemistry, Karachi university, Karachi, Pakistan. bashafz@gmail.com.
authors.forename: Fatima
authors.initials: F
authors.lastname: Basha
authors.forename: Syed K
authors.initials: SK
authors.lastname: Ali
authors.forename: Paul R
authors.initials: PR
authors.lastname: Hanson
authors.forename: Berl R
authors.initials: BR
authors.lastname: Oakley
authors.forename: Heather
authors.initials: H
authors.lastname: Hajovsky
authors.forename: Lester A
authors.initials: LA
authors.lastname: Mitscher
mesh_terms: D000818:Animals; D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D006801:Humans; D009262:Nails / Q000382:microbiology; D014009:Onychomycosis / Q000188:drug therapy*
chemical_list: D000935:Antifungal Agents