title: The Risk of Sleep Disorder Among Persons with Mild Traumatic Brain Injury.
abstract: Sleep disorders and mild traumatic brain injury (mTBI) are among the most commonly occurring neurological problems clinicians encounter simultaneously. Each can cause the other, and both share common predisposing factors. An important question that remains to be addressed is whether high-risk groups can be defined. We observed an accumulation of considerable knowledge on sleep dysfunction in mTBI in recently published works. The results highlight sleep disturbances in mTBI as the product of diverse internal and external influences, acting on a genetically determined substrate. This may partially explain the clinical heterogeneity of mTBI, pointing to the importance of establishing an accurate history on the onset and course of a specific sleep disorder in the early stages post-mTBI in the individual patient. Such an approach will aid not only diagnosis and treatment but may also lead to identification of disorders whose symptoms mimic those of TBI and thereby direct the most suitable treatment and management.
authors.affiliation: Acquired Brain Injury Lab, Rehabilitation Science Institute, University of Toronto, Toronto Rehabilitation Institute, 550 University Avenue, Rm 11207, Toronto, ON, M5G 2A2, Canada. tatyana.mollayeva@utoronto.ca.
authors.forename: Tatyana
authors.initials: T
authors.lastname: Mollayeva
authors.affiliation: Department of Cell & Systems Biology, University of Toronto, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.
authors.forename: Shirin
authors.initials: S
authors.lastname: Mollayeva
authors.affiliation: Acquired Brain Injury Lab, Rehabilitation Science Institute, University of Toronto, 160-500 University Ave., Toronto, ON, M5G 1V7, Canada.
authors.forename: Angela
authors.initials: A
authors.lastname: Colantonio
mesh_terms: D000818:Animals; D001921:Brain / Q000473:pathology; D001924:Brain Concussion / Q000150:complications* / Q000473:pathology; D006801:Humans; D012307:Risk Factors; D012893:Sleep Wake Disorders / Q000209:etiology* / Q000235:genetics; D014851:Wakefulness
keywords: Concussion; Mild traumatic brain injury; Risk; Sleep disorders