title: [Dongfeng-Tongji cohort: methodology of the survey and the characteristics of baseline and initial population of follow-up program].
abstract: OBJECTIVE
  To explore the effects of related environment, occupational, lifestyle, genetic factors as well as their interactions on the etiology of major chronic diseases in an occupational population.
  
  
  METHODS
  Dongfeng-Tongji cohort (DFTJ cohort), one of the large prospective cohort studies with biobank. Baseline study was conducted in Shiyan city, Hubei province from 2008 to 2009. This cohort study included questionnaire, physical examination and tests on blood samples. Dongfeng-Tongji cohort was followed up every 5 years and the first follow-up program was completed, from April to October in 2013. During the first follow-up period in 2013, questionnaire, physical examination, clinical and blood sample tests were conducted again.
  
  
  RESULTS
  27 009 retired participants with mean age of 63.6 years including 44.6% males, were recruited in this study. In the first follow-up program in 2013, among 38 295 subjects (44.7% males), 40.5% of them received diploma from high school or above. Prevalence rates of current regular smokers were 33.6% in men and 2.0% in women and the rates on current alcohol drinkers were 39.9% in men and 10.6% in women. The prevalence rates on self-reported hypertension, hypercholesterolemia, diabetes mellitus, coronary heart disease, stroke, chronic bronchitis, and asthma were 41.1%, 24.3%, 13.9%, 16.7%, 5.1%, 12.7% and 4.0%, respectively. The self-reported prevalence of hypertension and stroke in males was higher than that in females. 25 978 individuals who were involved in the baseline database successfully completed the followed up program in 2013, with the follow-up rate as 96.2%.
  
  
  CONCLUSIONS
  The DFTJ cohort study offered us an opportunity to explore the effects of environmental, genetic, as well as their interactions with major chronic diseases in a Chinese occupational population.
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Meian
authors.initials: M
authors.lastname: He
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Ce
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Jiang
authors.initials: J
authors.lastname: Zhu
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Yao
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Xiulou
authors.initials: X
authors.lastname: Li
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yuan
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Feng
authors.initials: F
authors.lastname: Wang
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Yuewei
authors.initials: Y
authors.lastname: Liu
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Chen
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Xinwen
authors.initials: X
authors.lastname: Min
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Han
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Guan
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Fang
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Liang
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Youjie
authors.initials: Y
authors.lastname: Wang
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Wei
authors.affiliation: Social Insurance Center, Dongfeng Motor Corporation, Shiyan 442008, Hubei, China.
authors.forename: Jichun
authors.initials: J
authors.lastname: Liu
authors.affiliation: Social Insurance Center, Dongfeng Motor Corporation, Shiyan 442008, Hubei, China.
authors.forename: Wenhu
authors.initials: W
authors.lastname: Si
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Miao
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Dongfeng
authors.initials: D
authors.lastname: Li
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Jianru
authors.initials: J
authors.lastname: Zheng
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Xiaomin
authors.initials: X
authors.lastname: Zhang
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Huan
authors.initials: H
authors.lastname: Guo
authors.affiliation: Dongfeng Central Hospital, Dongfeng Motor Corporation and Hubei University of Medicine, Shiyan 442008, Hubei, China.
authors.forename: Handong
authors.initials: H
authors.lastname: Yang
authors.affiliation: Departments of Nutrition and Epidemiology, Harvard School of Public Health, Boston, 02115, Massachusetts, USA.
authors.forename: Frank B
authors.initials: FB
authors.lastname: Hu
authors.affiliation: MOE Key Lab of Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China.
authors.forename: Tangchun
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authors.lastname: Wu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000428:Alcohol Drinking / Q000453:epidemiology; D044466:Asian People / Q000706:statistics & numerical data*; D002908:Chronic Disease / Q000208:ethnology*; D003920:Diabetes Mellitus / Q000453:epidemiology; D004777:Environment; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006937:Hypercholesterolemia / Q000453:epidemiology; D006973:Hypertension / Q000453:epidemiology; D008019:Life Style; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D017584:Reproductive History; D011795:Surveys and Questionnaires