title: Comparative analysis of the GNAQ, GNA11, SF3B1, and EIF1AX driver mutations in melanoma and across the cancer spectrum.
authors.affiliation: Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: Douglas B
authors.initials: DB
authors.lastname: Johnson
authors.affiliation: Department of Melanoma Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.|Department of Systems Biology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Roszik
authors.affiliation: Melanoma and Immunotherapeutics Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.
authors.forename: Alexander N
authors.initials: AN
authors.lastname: Shoushtari
authors.affiliation: Department of Cutaneous Oncology, Moffitt Cancer Center, Tampa, FL, USA.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Eroglu
authors.affiliation: Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.|Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: Justin M
authors.initials: JM
authors.lastname: Balko
authors.affiliation: School of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: Catherine
authors.initials: C
authors.lastname: Higham
authors.affiliation: Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: Igor
authors.initials: I
authors.lastname: Puzanov
authors.affiliation: Department of Melanoma Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
authors.forename: Sapna P
authors.initials: SP
authors.lastname: Patel
authors.affiliation: Department of Medicine, Division of Hematology/Oncology, Vanderbilt University Medical Center, Nashville, TN, USA.
authors.forename: Jeffrey A
authors.initials: JA
authors.lastname: Sosman
authors.affiliation: Department of Melanoma Medical Oncology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.|Department of Systems Biology, MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
authors.forename: Scott E
authors.initials: SE
authors.lastname: Woodman
mesh_terms: D015977:Eukaryotic Initiation Factor-1 / Q000235:genetics*; D044385:GTP-Binding Protein alpha Subunits / Q000235:genetics*; D043802:GTP-Binding Protein alpha Subunits, Gq-G11 / Q000235:genetics*; D052138:Genes, Neoplasm; D006801:Humans; D007167:Immunotherapy; D008545:Melanoma / Q000453:epidemiology / Q000235:genetics* / Q000628:therapy; D009154:Mutation; D020125:Mutation, Missense; D009369:Neoplasms / Q000453:epidemiology / Q000235:genetics*; D010750:Phosphoproteins / Q000235:genetics*; D017354:Point Mutation; D011379:Prognosis; D000072260:RNA Splicing Factors / Q000235:genetics*
chemical_list: D015977:Eukaryotic Initiation Factor-1; C554062:GNA11 protein, human; C554061:GNAQ protein, human; D044385:GTP-Binding Protein alpha Subunits; D010750:Phosphoproteins; D000072260:RNA Splicing Factors; C112491:SF3B1 protein, human; C026022:eukaryotic peptide initiation factor-1A; D043802:GTP-Binding Protein alpha Subunits, Gq-G11