title: Computed Tomography-Guided Radiofrequency Ablation Following Transcatheter Arterial Embolization in Treatment of Large Hepatic Hemangiomas.
abstract: The aim of the study was to evaluate the feasibility, safety, and efficacy of computed tomography (CT)-guided radiofrequency (RF) ablation combined with transcatheter arterial embolization (TAE) to treat large (≥10 cm) hepatic hemangiomas. We retrospectively reviewed our sequential experience with 15 large hepatic hemangiomas in 15 patients. The mean diameter of the 15 hemangiomas was 13.0 ± 2.2 cm (10.0-16.0 cm). RF ablation combined with TAE treatment was performed successfully in all patients. The mean diameter of the hemangiomas decreased from 13.0 ± 2.2 to 7.1 ± 2.0 cm (P < 0.001) after TAE treatment. Out of 15 hepatic hemangiomas, 14 (93.3%) showed no enhancement on CT or MRI indicating complete ablation after RF treatment. The mean diameter of the ablation zone decreased to 6.1 ± 2.0 cm 1 month after ablation and further decreased to 4.9 ± 1.6 cm 6 months after ablation. There were 6 complications related to the ablation in 4 patients. According to the Dindo-Clavien classification, all the complications were minor (Grade I). RF ablation combined with TAE is a safe and effective treatment for large hepatic hemangiomas. TAE can improve the disruption of lesion blood supply and reduce lesion size to facilitate subsequent RF ablation and reduce the risk of ablation-related complications.
authors.affiliation: From the Department of Radiology (JJ, JT, JS), Lishui Central Hospital, The Fifth Affiliated Hospital of Wenzhou Medical College, Zhejiang; Department of Hepatobiliary Surgery (JG, WS) Beijing Chao-yang Hospital Affiliated with Capital Medical University, Beijing; and Department of General Practice (LZ), Beijing Chao-yang Hospital Affiliated with Capital Medical University, Beijing, China.
authors.forename: Jiansong
authors.initials: J
authors.lastname: Ji
authors.forename: Jun
authors.initials: J
authors.lastname: Gao
authors.forename: Lizhen
authors.initials: L
authors.lastname: Zhao
authors.forename: Jianfei
authors.initials: J
authors.lastname: Tu
authors.forename: Jingjing
authors.initials: J
authors.lastname: Song
authors.forename: Wenbing
authors.initials: W
authors.lastname: Sun
mesh_terms: D000328:Adult; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D004621:Embolization, Therapeutic / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006391:Hemangioma / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D015641:Radiography, Interventional; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed