title: Treatment of striae distensae with needling therapy versus microdermabrasion with sonophoresis.
abstract: Striae distensae (SD) is a challenging cosmetic problem for which various treatment modalities have been applied. Our aim was to evaluate the efficacy and tolerability of needling therapy versus microdermabrasion with sonophoresis in the treatment of SD.
  
  
  METHODS
  Forty female patients with SD (mean duration 2.98 ± 2.66) were enrolled in this study. Patients were assigned to two groups, Group 1 treated with needling therapy and Group 2 treated by microdermabrasion with sonophoresis. In Group 1, three sessions of needling therapy were performed for each patient with 4-week interval between the sessions, while in Group 2, ten sessions of combined microdermabrasion and sonophoresis were performed for each patient. Skin biopsies were taken from the most atrophic site stained with hematoxylin and eosin stain and Masson trichrome stains to study the histopathological changes and efficacy of treatment, respectively.
  
  
  RESULTS
  There was a significant clinical improvement in SD in Group 1 compared with Group 2. Amount of collagen, number of fibroblasts, and epidermal thickness increased in the dermis at the end of treatment sessions (90% in Group 1 compared to 50% in Group 2).
  
  
  CONCLUSIONS
  Needling therapy is an easy, safe, and economic method and considered as a suitable modality in management of striae.
authors.affiliation: a Departments of Dermatology , Venereology and Andrology, Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.
authors.forename: Amani
authors.initials: A
authors.lastname: Nassar
authors.affiliation: a Departments of Dermatology , Venereology and Andrology, Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.
authors.forename: Soheir
authors.initials: S
authors.lastname: Ghomey
authors.affiliation: b Department of Pathology , Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.
authors.forename: Yosria
authors.initials: Y
authors.lastname: El Gohary
authors.affiliation: a Departments of Dermatology , Venereology and Andrology, Faculty of Human Medicine , Zagazig University, Zagazig , Egypt.
authors.forename: Fatma
authors.initials: F
authors.lastname: El-Desoky
mesh_terms: D000328:Adult; D003094:Collagen; D003869:Dermabrasion / Q000379:methods*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009339:Needles; D017060:Patient Satisfaction; D057896:Striae Distensae / Q000473:pathology / Q000532:radiotherapy / Q000628:therapy*; D014464:Ultrasonic Therapy / Q000379:methods*; D000069453:Ultrasonic Waves
chemical_list: D003094:Collagen
keywords: Histopathology; microdermabrasion with sonophoresis; needling therapy; striae distensae