title: I-TiO2/PVC film with highly photocatalytic antibacterial activity under visible light.
abstract: Iodine-modified TiO2(I-TiO2) film were coated on medical-grade PVC material by impregnation-deposition method and subsequently characterized by XRD, SEM, TEM, AFM, DRS and XPS. The photocatalytic anti-bacterial activity of I-TiO2/PVC was investigated both by in vitro anti-bacterial experiments and by clinical study. The results revealed that I-TiO2/PVC exhibit excellent photocatalytic antibacterial activity, which can destroy the propagation of the Escherichia coli and cause the deactivation and death of most E. coli bacteria within 30min visible light illumination. Clinical study on animals showed that I-TiO2 coated on PVC decrease the formation of biofilm on PVC surface in the mechanical ventilation. Furthermore, I-TiO2/PVC can effectively reduce inflammation of tracheal tissue of bam suckling pig and prevents the occurrence of VAP.
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Weihua
authors.initials: W
authors.lastname: Deng
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Shangbo
authors.initials: S
authors.lastname: Ning
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Qianying
authors.initials: Q
authors.lastname: Lin
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Hualei
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Tanghua
authors.initials: T
authors.lastname: Zhou
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China. Electronic address: lhx@fzu.edu.cn.
authors.forename: Huaxiang
authors.initials: H
authors.lastname: Lin
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Jinlin
authors.initials: J
authors.lastname: Long
authors.affiliation: First Affiliated Hospital, Fujian Medical University, Fuzhou, 350002, China.
authors.forename: Qun
authors.initials: Q
authors.lastname: Lin
authors.affiliation: Research Institute of Photocatalysis, State Key Laboratory of Photocatalysis on Energy and Environment, Fuzhou University, Fuzhou 350002, PR China.
authors.forename: Xuxu
authors.initials: X
authors.lastname: Wang
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D018441:Biofilms / Q000187:drug effects / Q000528:radiation effects; D002384:Catalysis / Q000187:drug effects / Q000528:radiation effects; D004926:Escherichia coli / Q000187:drug effects / Q000502:physiology / Q000528:radiation effects / Q000648:ultrastructure; D007454:Iodides / Q000494:pharmacology*; D008027:Light; D008168:Lung / Q000473:pathology; D056951:Photoelectron Spectroscopy; D053717:Pneumonia, Ventilator-Associated / Q000473:pathology; D011143:Polyvinyl Chloride / Q000494:pharmacology*; D012121:Respiration, Artificial; D013056:Spectrophotometry, Ultraviolet; D034421:Sus scrofa; D014025:Titanium / Q000494:pharmacology*; D014961:X-Ray Diffraction
chemical_list: D000900:Anti-Bacterial Agents; D007454:Iodides; C009495:titanium dioxide; D011143:Polyvinyl Chloride; D014025:Titanium
keywords: Antibacterial activity; Biofilm; Iodine-modified TiO(2) film; PVC; Photocatalysis