title: The validity and reliability of the diagnosis of hyperkinetic disorders in the Danish Psychiatric Central Research Registry.
abstract: To validate the diagnosis of hyperkinetic disorders (HD) in the Danish Psychiatric Central Research Registry (DPCRR) for children and adolescents aged 4 to 15 given in the years 1995 to 2005.
  
  
  
  From a total of 4568 participants, a representative random subsample of n=387 patients were used to validate the diagnosis. Patient files were systematically scored for the presence of ICD-10 criteria for HD and oppositional defiant disorder/conduct disorder (ODD/CD; F91). Further to this, an inter-rater reliability study was also conducted, whereby two experienced child and adolescent psychiatrists who were blind to patients discharge diagnoses, rated a random subsample of n=101 participants.
  
  
  
  Information was available for 372 out of 387 patients. Out of n=372 available files, n=324 (86.8%) were evaluated to fulfil diagnostic criteria for HD. Due to missing information it was not possible to reach a conclusion for 5.1% of the cases, 3.8% of the diagnoses were registration errors, and in 4.3% of the files the diagnosis had to be rejected. Inter-rater agreement was high (κ=0.83, z=10.9, P<.001). The validity of hyperkinetic disorders, unspecified (F90.9) was lower and comorbid CD/ODD were under-diagnosed in the sample. All participants fulfilling HD criteria also fulfilled DSM-5-criteria for ADHD.
  
  
  
  The risk of misclassification of patients with HD in the DPCRR is relatively low, with the exception of the diagnosis of hyperkinetic disorders, unspecified (F90.9).
authors.affiliation: Research Unit of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark. Electronic address: christina.j@rn.dk.
authors.forename: C
authors.initials: C
authors.lastname: Mohr-Jensen
authors.affiliation: Child and Adolescent Mental Health Centre, Mental Health Services, Capital Region of Denmark and Institute of Clinical Medicine, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
authors.forename: S
authors.initials: S
authors.lastname: Vinkel Koch
authors.affiliation: Research Unit of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark.
authors.forename: M
authors.initials: M
authors.lastname: Briciet Lauritsen
authors.affiliation: Research Unit of Child and Adolescent Psychiatry, Aalborg Psychiatric Hospital, Aalborg University Hospital, Aalborg, Denmark; Clinical Psychology and Epidemiology, Department of Psychology, University of Basel, Basel, Switzerland; Department of Child and Adolescent Psychiatry, University of Zurich, Zurich, Switzerland.
authors.forename: H-C
authors.initials: HC
authors.lastname: Steinhausen
mesh_terms: D000293:Adolescent; D001289:Attention Deficit Disorder with Hyperactivity / Q000175:diagnosis* / Q000523:psychology; D019958:Attention Deficit and Disruptive Behavior Disorders / Q000175:diagnosis*; D002648:Child; D015897:Comorbidity; D019955:Conduct Disorder / Q000175:diagnosis; D005260:Female; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D012042:Registries; D015203:Reproducibility of Results; D011795:Surveys and Questionnaires / Q000592:standards*
keywords: ADHD; Diagnostic validity; Hyperkinetic disorders; Research registry