title: [Testosterone therapy].
abstract: Hormone replacement therapy with testosterone has become well-established over the course of time. The initial substantial concerns with respect to complications and potential adverse events, particularly in older patients, were proven to be unfounded over time. Testosterone therapy has therefore gradually become a regular treatment modality in urological practice. It has also been shown to represent a valuable tool as supportive treatment for patients with erectile dysfunction and hypogonadism. A variety of testosterone preparations are available for treatment. Recent pharmaceutical developments have greatly improved the practicability and ease of administration for patients. Several guidelines have been developed that provide clearly formulated standards and instructions for indications, contraindications, application, risk factors and monitoring of testosterone therapy. Adverse events affecting the cardiovascular system and especially diseases of the prostate gland are of great importance, thus making the urologist the primary partner in the treatment of patients with testosterone deficiency.
authors.affiliation: Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus-Liebig-Universität Gießen, Rudolf-Buchheim-Straße 7, 35385, Gießen, Deutschland. Thorsten.Diemer@chiru.med.uni-giessen.de.
authors.forename: T
authors.initials: T
authors.lastname: Diemer
authors.affiliation: Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus-Liebig-Universität Gießen, Rudolf-Buchheim-Straße 7, 35385, Gießen, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Hauptmann
authors.affiliation: Klinik und Poliklinik für Urologie, Kinderurologie und Andrologie, Universitätsklinikum Gießen und Marburg GmbH, Standort Gießen, Justus-Liebig-Universität Gießen, Rudolf-Buchheim-Straße 7, 35385, Gießen, Deutschland.
authors.forename: F M E
authors.initials: FM
authors.lastname: Wagenlehner
mesh_terms: D002318:Cardiovascular Diseases / Q000139:chemically induced / Q000517:prevention & control; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D007172:Erectile Dysfunction / Q000188:drug therapy* / Q000517:prevention & control; D019317:Evidence-Based Medicine; D005260:Female; D020249:Hormone Replacement Therapy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007006:Hypogonadism / Q000188:drug therapy* / Q000517:prevention & control; D008297:Male; D011469:Prostatic Diseases / Q000139:chemically induced / Q000517:prevention & control; D013739:Testosterone / Q000008:administration & dosage* / Q000009:adverse effects / Q000172:deficiency*; D016896:Treatment Outcome
chemical_list: D013739:Testosterone
keywords: Erectile dysfunction; Hormone replacement therapy; Hypogonadism; Late-onset hypogonadism; Testosterone