title: Adding Insult to Injury: Exacerbating TB Risk with Smoking.
abstract: Inhaled environmental pollutants, most prominently from cigarettes, confer an increased risk of tuberculosis. A recent study published in Cell by Berg et al., (2016) using the zebrafish model of Mycobacterium marinum infection provides new insights into the role of macrophage lysosomal engorgement in compromising host defense against mycobacteria.
authors.affiliation: Immunology Program, Sloan Kettering Institute, and Division of Infectious Diseases, Memorial Sloan Kettering Cancer Center, Box 477, 1275 York Avenue, New York, NY 10065, USA. Electronic address: glickmam@mskcc.org.
authors.forename: Michael S
authors.initials: MS
authors.lastname: Glickman
authors.affiliation: Division of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, 622 West 168 Street, New York, NY 10032, USA.
authors.forename: Neil
authors.initials: N
authors.lastname: Schluger
mesh_terms: D000818:Animals; D006801:Humans; D009161:Mycobacterium; D009165:Mycobacterium Infections, Nontuberculous; D019910:Mycobacterium marinum; D012907:Smoking; D014376:Tuberculosis / Q000382:microbiology; D015027:Zebrafish / Q000382:microbiology