title: [Spondylarthropathies: conventional treatments and anti-TNF].
abstract: Non-steroidal anti-inflammatory drugs (NSAID) are the first line treatment for spondylarthritis. NSAIDs are effective when used continuously or on demand, in short or long-term use. An effect on radiologic progression of the spine is still controversial. However, physicians have to be aware of potential cardiovascular, renal or gastro-intestinal secondary effects when prescribing NSAIDs. DMARDs like methotrexate or systemic corticosteroids are generally not recommended for the treatment of spondylarthritis. After NSAIDs failure, a TNF inhibitor can be used. 5 anti-TNF are available in Switzerland and they are all effective in this disease. Before starting an anti-TNF treatment, a screening is mandatory. Patients treated with an anti-TNF must be followed regularly.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Dumusc
authors.forename: Alexander
authors.initials: A
authors.lastname: So
mesh_terms: D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use*; D018501:Antirheumatic Agents / Q000627:therapeutic use*; D006801:Humans; D015201:Meta-Analysis as Topic; D016032:Randomized Controlled Trials as Topic; D025242:Spondylarthropathies / Q000188:drug therapy*; D013557:Switzerland; D013997:Time Factors; D016896:Treatment Outcome; D014409:Tumor Necrosis Factor-alpha / Q000037:antagonists & inhibitors*
chemical_list: D000894:Anti-Inflammatory Agents, Non-Steroidal; D018501:Antirheumatic Agents; D014409:Tumor Necrosis Factor-alpha