title: Successful Fecal Microbiota Transplantation as an Initial Therapy for Clostridium difficile Infection on an Outpatient Basis.
abstract: A 64-year-old woman developed diarrhea after taking clindamycin for a dental infection. We diagnosed her with Clostridium difficile infection (CDI) and performed fecal microbiota transplantation (FMT) as the initial therapy using colonoscopy on an outpatient basis. The frequency of her bowel movements decreased from 10 times per day to two times per day three days after the procedure. The key component of FMT is to restructure the protective microbiome of the natural intestinal flora. We consider that FMT could be used as an effective first-line therapy for CDI if the efficacy and safety of this procedure is established in the future.
authors.affiliation: Department of General Internal Medicine, Kitano Hospital, Tazuke-Kofukai, Medical Research Institute, Japan.
authors.forename: Takamasa
authors.initials: T
authors.lastname: Tanaka
authors.forename: Haru
authors.initials: H
authors.lastname: Kato
authors.forename: Takushi
authors.initials: T
authors.lastname: Fujimoto
mesh_terms: D016360:Clostridioides difficile; D003015:Clostridium Infections / Q000628:therapy*; D003113:Colonoscopy / Q000379:methods; D000069467:Fecal Microbiota Transplantation / Q000379:methods*; D005260:Female; D000069196:Gastrointestinal Microbiome; D006801:Humans; D008875:Middle Aged; D010045:Outpatients; D012008:Recurrence