title: [Consensus validation of a tool to identify inappropriate prescribing in pediatrics (POPI)].
abstract: OBJECTIVE
  Medication errors including inappropriate prescriptions and drug omissions are one of the causes of adverse drug events in children. Our aim was to develop a preliminary screening tool to detect omissions and inappropriate prescriptions in pediatrics based on French and international guidelines.
  
  
  METHODS
  Disease classification was based on the prevalence rate of pathology and hospital statistics. The criteria were obtained by reviewing many French and international references. The Delphi consensus technique was used to establish the content validity of POPI. The level of agreement and the proposals of healthcare professionals was noted on a nine-point Likert scale.
  
  
  RESULTS
  The criteria were categorized according to the main physiological systems (gastroenterology, respiratory infections, pain, neurology, dermatology, and miscellaneous). They were distributed to 16 French pediatric panelists (eight pharmacists, eight pediatricians who were hospital-based [50%] or working in the community [50%]). After two rounds of the Delphi process, 101 of 108 criteria were chosen with strong consensus (76 inappropriate prescriptions and 25 omissions).
  
  
  CONCLUSIONS
  POPI is the first screening tool to detect inappropriate prescriptions and omissions in pediatrics. It is now necessary to conduct a prospective study to determine inter-rater reliability and the tool's detection capacity.
authors.affiliation: Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Inserm ECEVE unité 1123, 75019 Paris, France; Groupe pédiatrie de la Société française de pharmacie clinique, France. Electronic address: sonia.prot-labarthe@aphp.fr.
authors.forename: S
authors.initials: S
authors.lastname: Prot-Labarthe
authors.affiliation: Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: T
authors.initials: T
authors.lastname: Weil
authors.affiliation: Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: N P K
authors.initials: NP
authors.lastname: Nguyen
authors.affiliation: Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Berthe-Aucejo
authors.affiliation: Service d'accueil des urgences, hôpital Necker, AP-HP, 75015 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Angoulvant
authors.affiliation: Unité d'épidémiologie clinique, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: R
authors.initials: R
authors.lastname: Boulkedid
authors.affiliation: Inserm ECEVE unité 1123, 75019 Paris, France; Unité d'épidémiologie clinique, hôpital Robert-Debré, AP-HP, 75019 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Alberti
authors.affiliation: Département de pharmacie, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Groupe pédiatrie de la Société française de pharmacie clinique, France; Pharmacie clinique, université Paris Descartes, Sorbonne Paris Cité, 75006 Paris, France; EA3412, laboratoire éducations et pratiques de santé, université Paris XIII, 93017 Bobigny, France.
authors.forename: O
authors.initials: O
authors.lastname: Bourdon
mesh_terms: D000328:Adult; D000368:Aged; D032921:Consensus; D011307:Drug Prescriptions / Q000706:statistics & numerical data*; D005260:Female; D005602:France / Q000453:epidemiology; D017408:Guidelines as Topic; D006801:Humans; D057970:Inappropriate Prescribing / Q000706:statistics & numerical data*; D008297:Male; D008875:Middle Aged; D010372:Pediatrics; D010595:Pharmacists / Q000706:statistics & numerical data; D010820:Physicians / Q000706:statistics & numerical data; D010818:Practice Patterns, Physicians' / Q000706:statistics & numerical data*; D015995:Prevalence; D015203:Reproducibility of Results