title: Current and future strategies for treatment of glioma.
abstract: Gliomas are one of the most common types of primary brain tumors and have remained particularly challenging to treat. This review illustrates a multidisciplinary approach to the treatment of glioma and glioblastoma. We will review current advances in surgical approaches, novel imaging techniques, advanced molecular characterization of tumors and translational efforts for treatment. We will focus on current clinical trials as well as the pursuit of personalized or precision therapy. We will also comment on the importance of both quality of life of our patients and their care givers.
authors.affiliation: Division of Neuro-Oncology, Department of Neurological Surgery, University of California, San Francisco, CA, USA. Nancyann.oberheimbush@ucsf.edu.
authors.forename: Nancy Ann Oberheim
authors.initials: NA
authors.lastname: Bush
authors.affiliation: Division of Neuro-Oncology, Department of Neurological Surgery, University of California, San Francisco, CA, USA.
authors.forename: Susan M
authors.initials: SM
authors.lastname: Chang
authors.affiliation: Department of Neurological Surgery, University of California, San Francisco, CA, USA.
authors.forename: Mitchel S
authors.initials: MS
authors.lastname: Berger
mesh_terms: D001921:Brain / Q000473:pathology* / Q000601:surgery; D001932:Brain Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D005910:Glioma / Q000145:classification / Q000473:pathology* / Q000628:therapy*; D006801:Humans; D011788:Quality of Life; D033581:Stem Cell Transplantation; D013234:Stem Cells / Q000166:cytology*
keywords: Glioblastoma; Glioma; Pharmacology; Quality of life; Review; Stem cell; Targeted therapy; Treatment