title: Rapid onset of squamous cell carcinoma in a thin skin graft donor site.
abstract: BACKGROUND
  Squamous cell carcinomas are malignant tumours of epithelial origin that can appear on sites subjected to chronic inflammation after a period of several years. The rapid development of squamous cell carcinoma at the donor site for a thin skin graft is a rare and poorly understood situation.
  
  
  METHODS
  We report the case of a patient undergoing thin skin grafting to cover the area of removal of a vertex squamous cell carcinoma and in whom squamous cell carcinoma appeared at the donor site within 9 weeks.
  
  
  CONCLUSIONS
  In our case, we ruled out intraoperative contamination because two sets of surgical instruments were used. Given the number of cases reported in the literature, a chance event seems unlikely. The hypothesis of an acute inflammatory process caused by scarring of the thin skin graft site appears to us the most convincing. Development of cancer at the graft donor site may thus be added to the list of complications of thin skin grafting.
authors.affiliation: Department of plastic, reconstructive and aesthetic surgery, hôpital Trousseau, CHU de Tours, avenue de la République, 37170 Chambray-Lès-Tours, France. Electronic address: camillanipi@hotmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Herard
authors.affiliation: Department of plastic, reconstructive and aesthetic surgery, CHU d'Angers, 4, rue Larrey, 49933 Angers, France.
authors.forename: D
authors.initials: D
authors.lastname: Arnaud
authors.affiliation: Department of plastic, reconstructive and aesthetic surgery, hôpital Trousseau, CHU de Tours, avenue de la République, 37170 Chambray-Lès-Tours, France.
authors.forename: D
authors.initials: D
authors.lastname: Goga
authors.affiliation: Department of plastic, reconstructive and aesthetic surgery, CHU d'Angers, 4, rue Larrey, 49933 Angers, France.
authors.forename: P
authors.initials: P
authors.lastname: Rousseau
authors.affiliation: Department of plastic, reconstructive and aesthetic surgery, polyclinique du Parc, 49300 Cholet, France.
authors.forename: B
authors.initials: B
authors.lastname: Potier
mesh_terms: D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D012535:Scalp / Q000473:pathology / Q000601:surgery; D012878:Skin Neoplasms / Q000473:pathology* / Q000601:surgery; D016038:Skin Transplantation; D060053:Transplant Donor Site / Q000473:pathology*
keywords: Carcinome épidermoïde; Donor site; Greffe de peau mince; Inflammation; Site donneur de greffe de peau; Squamous cell carcinoma; Thin skin graft