title: Ulcerative Colitis-associated Cancer/Dysplasia Detected Using Surveillance Colonoscopy Performed in the Clinical Remission Phase: A Report of Five Cases.
abstract: We herein report five cases of ulcerative colitis-associated cancer/dysplasia. Although clinical remission had been achieved in all patients, mucosal inflammation had been resolved in only one patient. Thus, in order to prevent cancer from developing, appropriate medical therapy aiming not only to relieve the clinical symptoms, but also to suppress chronic inflammation appears to be necessary. Moreover, cancer occurred as early as 4 years after the diagnosis in one patient. In patients without complete resolution of mucosal inflammation, careful surveillance colonoscopy should be initiated in the early phase.
authors.affiliation: Department of Gastroenterology, Dokkyo Medical University, Japan.
authors.forename: Ruiko
authors.initials: R
authors.lastname: Muraoka
authors.forename: Keiichi
authors.initials: K
authors.lastname: Tominaga
authors.forename: Xubin
authors.initials: X
authors.lastname: Sai
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Takenaka
authors.forename: Takeshi
authors.initials: T
authors.lastname: Sugaya
authors.forename: Masakazu
authors.initials: M
authors.lastname: Nakano
authors.forename: Naoto
authors.initials: N
authors.lastname: Yoshitake
authors.forename: Satoru
authors.initials: S
authors.lastname: Yamaguchi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Nagata
authors.forename: Hidetsugu
authors.initials: H
authors.lastname: Yamagishi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Mitomi
authors.forename: Hideyuki
authors.initials: H
authors.lastname: Hiraishi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D003093:Colitis, Ulcerative / Q000150:complications*; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000209:etiology* / Q000473:pathology; D005260:Female; D006801:Humans; D006965:Hyperplasia; D007249:Inflammation; D008297:Male; D008875:Middle Aged