title: [Surgical Treatment for Refractory Metastatic Lung Tumors from Urachal Carcinoma after Chemotherapy].
abstract: A 33-year-old man underwent radical surgery for urachal cancer. Histology of the cancer revealed an adenocarcinoma of the urachus, Sheldon stage ⅢA. He developed a right lung nodule 23 months after the surgery. Partial lobectomy was performed;it revealed an adenocarcinoma compatible with urachal carcinoma. Additionally, 2 right lung metastases measuring 0.5 cm and 1.6 cm in diameter were found 12 months after partial lobectomy. The patient was treated with 4 different chemotherapy regimens including TS-1 and cisplatin, paclitaxel, folinic acid・fluorouracil・oxaliplatin(FOLFOX), and folinic acid・fluorouracil・irinotecan (FOLFIRI). Computed tomography reports showed progression of the pulmonary nodules, now measuring 1.4 cm and 10 cm in diameter. There was no evidence of distant metastasis except for in the lung and local recurrence. Right pneumonectomy was performed;the histology of the specimen confirmed urachal adenocarcinoma. Three months later, he developed cerebellar metastasis. The tumor was removed by neurosurgeons. The patient died of widespread metastases 6 months after the pneumonectomy.
authors.affiliation: Department of Thoracic Surgery, Sapporo Medical Center Tonan Hospital, Sapporo, Japan.
authors.forename: Tetsuyuki
authors.initials: T
authors.lastname: Okubo
authors.forename: Masaya
authors.initials: M
authors.lastname: Kawada
authors.forename: Daisuke
authors.initials: D
authors.lastname: Saikawa
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Suzuki
authors.forename: Yo
authors.initials: Y
authors.lastname: Kawarada
authors.forename: Shuji
authors.initials: S
authors.lastname: Kitashiro
authors.forename: Shunichi
authors.initials: S
authors.lastname: Okushiba
mesh_terms: D000230:Adenocarcinoma / Q000188:drug therapy / Q000473:pathology* / Q000556:secondary / Q000601:surgery; D000328:Adult; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000556:secondary* / Q000601:surgery*; D008297:Male; D001749:Urinary Bladder Neoplasms / Q000473:pathology*