title: Plant sphingolipids: Their importance in cellular organization and adaption.
abstract: Sphingolipids and their phosphorylated derivatives are ubiquitous bio-active components of cells. They are structural elements in the lipid bilayer and contribute to the dynamic nature of the membrane. They have been implicated in many cellular processes in yeast and animal cells, including aspects of signaling, apoptosis, and senescence. Although sphingolipids have a better defined role in animal systems, they have been shown to be central to many essential processes in plants including but not limited to, pollen development, signal transduction and in the response to biotic and abiotic stress. A fuller understanding of the roles of sphingolipids within plants has been facilitated by classical biochemical studies and the identification of mutants of model species. Recently the development of powerful mass spectrometry techniques hailed the advent of the emerging field of lipidomics enabling more accurate sphingolipid detection and quantitation. This review will consider plant sphingolipid biosynthesis and function in the context of these new developments. This article is part of a Special Issue entitled: Plant Lipid Biology edited by Kent D. Chapman and Ivo Feussner.
authors.affiliation: Biological Chemistry and Crop Protection, Rothamsted Research, Harpenden AL5 2JQ, UK. Electronic address: louise.michaelson@rothamsted.ac.uk.
authors.forename: Louise V
authors.initials: LV
authors.lastname: Michaelson
authors.affiliation: Biological Chemistry and Crop Protection, Rothamsted Research, Harpenden AL5 2JQ, UK. Electronic address: Johnathan.Napier@rothamsted.ac.uk.
authors.forename: Johnathan A
authors.initials: JA
authors.lastname: Napier
authors.affiliation: Ecole Normale Supérieure-PSL Research University, Département de Chimie, Sorbonne Universités - UPMC Univ Paris 06, CNRS UMR 8640 PASTEUR, Paris, France. Electronic address: dmolino@gmail.com.
authors.forename: Diana
authors.initials: D
authors.lastname: Molino
authors.affiliation: INRA, Institut Jean-Pierre Bourgin, UMR 1318, ERL CNRS3559, Saclay Plant Sciences, Versailles, France; Agro Paris Tech, Institut Jean-Pierre Bourgin, UMR 1318, ERL CNRS3559, Saclay Plant Sciences, Versailles, France. Electronic address: Jean-Denis.Faure@versailles.inra.fr.
authors.forename: Jean-Denis
authors.initials: JD
authors.lastname: Faure
mesh_terms: D000064:Acclimatization / Q000235:genetics; D002462:Cell Membrane / Q000235:genetics* / Q000378:metabolism; D008051:Lipid Bilayers / Q000378:metabolism*; D010766:Phosphorylation; D011058:Pollen / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics; D013107:Sphingolipids / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D013312:Stress, Physiological / Q000235:genetics
chemical_list: D008051:Lipid Bilayers; D013107:Sphingolipids
keywords: Fatty acid; Glycans; Long chain base; Membrane; Phosphorylation