title: Effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts.
abstract: OBJECTIVE
  We aimed to evaluate the effectiveness of single-session ultrasound-guided percutaneous ethanol sclerotherapy in simple breast cysts.
  
  
  METHODS
  From January 2002 to January 2014, 35 simple breast cysts (mean volume, 8.2 mL; range, 4-33 mL) in 28 females (mean age, 39 years) were evaluated. In a single session, all cysts were aspirated using 20G needles, refilled with 99% ethanol (90% of the volume of the aspirated fluid), and reaspirated completely after 10 minutes of exposure under ultrasound guidance. Follow-up ultrasonography examinations were performed at one week, one month, three months, and six months for all patients and 12 months, 18 months, and 24 months for available patients. Follow- up duration varied between 6 and 24 months (mean, 15 months).
  
  
  RESULTS
  The technical success rate of ultrasound-guided percutaneous etha-nol sclerotherapy was 97%. The needle tip was dislocated and ethanol was given into the breast parenchyma in one patient (3%). One cyst (3%) was reaspirated at the first week follow-up due to intracystic hemorrhage. Of the 34 cysts treated, 25 (74%) completely responded to therapy and were no longer detectable on follow-up examinations. Eight cysts (24%) significantly decreased in size and then completely disappeared at six months. At the end of the follow-up period, the clinical success rate reached 100%, and none of the cysts were visible. Except mild to moderate sensation of burning or pain which disappeared or subsided significantly in a couple of minutes, no other complications were observed in patients.
  
  
  CONCLUSIONS
  Ultrasound-guided ethanol sclerotherapy is a fast, safe, and highly effective method in the treatment of simple breast cysts.
authors.affiliation: Department of Radiology, Yeditepe University Hospital, İstanbul, Turkey. draliozgen@hotmail.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Özgen
mesh_terms: D000328:Adult; D047688:Breast Cyst / Q000000981:diagnostic imaging* / Q000628:therapy*; D004322:Drainage / Q000295:instrumentation / Q000379:methods; D000431:Ethanol / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D015911:Sclerotherapy / Q000295:instrumentation / Q000379:methods*; D016896:Treatment Outcome; D014463:Ultrasonography; D055815:Young Adult
chemical_list: D000431:Ethanol