title: Malignant mesothelioma not related to asbestos exposure: Analytical scanning electron microscopic analysis of 83 cases and comparison with 442 asbestos-related cases.
abstract: Epidemiological studies indicate that 80-90% of mesotheliomas are asbestos related. This suggests that 10-20% are not. Lung fiber burden analysis provides objective information about past exposures to asbestos. We have performed lung fiber burden analysis on a large cohort of mesothelioma cases and compared the findings with a reference population. Herein we report our findings along with demographic and exposure data.
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Alyssa
authors.initials: A
authors.lastname: Kraynie
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Gustaaf G
authors.initials: GG
authors.lastname: de Ridder
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Thomas A
authors.initials: TA
authors.lastname: Sporn
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Elizabeth N
authors.initials: EN
authors.lastname: Pavlisko
authors.affiliation: a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
authors.forename: Victor L
authors.initials: VL
authors.lastname: Roggli
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001194:Asbestos / Q000032:analysis*; D005260:Female; D006801:Humans; D008168:Lung / Q000648:ultrastructure; D008297:Male; D008654:Mesothelioma / Q000473:pathology*; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000473:pathology*; D010997:Pleural Neoplasms / Q000473:pathology*
chemical_list: D001194:Asbestos
keywords: Asbestos exposure; asbestos related cases; electron microscopic analysis; malignant mesothelioma