title: Breeding animals for quality products: not only genetics.
abstract: The effect of the Developmental Origins of Health and Disease on the spread of non-communicable diseases is recognised by world agencies such as the United Nations and the World Health Organization. Early environmental effects on offspring phenotype also apply to domestic animals and their production traits. Herein, we show that maternal nutrition not only throughout pregnancy, but also in the periconception period can affect offspring phenotype through modifications of gametes, embryos and placental function. Because epigenetic mechanisms are key processes in mediating these effects, we propose that the study of epigenetic marks in gametes may provide additional information for domestic animal selection.
authors.affiliation: INRA, UMR 1198 Biologie du Développement et Reproduction, 78350 Jouy en Josas, France.
authors.forename: Pascale
authors.initials: P
authors.lastname: Chavatte-Palmer
authors.affiliation: INRA, UMR 1198 Biologie du Développement et Reproduction, 78350 Jouy en Josas, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Tarrade
authors.affiliation: INRA, UMR 1198 Biologie du Développement et Reproduction, 78350 Jouy en Josas, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Kiefer
authors.affiliation: INRA, UMR 1198 Biologie du Développement et Reproduction, 78350 Jouy en Josas, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Duranthon
authors.affiliation: INRA, UMR 1198 Biologie du Développement et Reproduction, 78350 Jouy en Josas, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Jammes
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D015415:Biomarkers / Q000032:analysis / Q000378:metabolism; D047108:Embryonic Development; D044127:Epigenesis, Genetic; D005260:Female; D047109:Fetal Development; D063427:Food Quality; D006197:Hair / Q000737:chemistry / Q000254:growth & development / Q000378:metabolism; D058751:Livestock / Q000254:growth & development / Q000502:physiology*; D008297:Male; D039382:Maternal Nutritional Physiological Phenomena; D008460:Meat / Q000032:analysis; D008892:Milk / Q000737:chemistry / Q000378:metabolism; D008954:Models, Biological; D010929:Placentation; D011247:Pregnancy; D011786:Quality Control; D000068618:Selective Breeding; D014480:United Nations; D014935:Wool / Q000737:chemistry / Q000254:growth & development* / Q000378:metabolism; D014944:World Health Organization
chemical_list: D015415:Biomarkers