title: Hyperbaric oxygen therapy and osteonecrosis.
abstract: Osteonecrosis of the jaw may be caused by radiation, medication, or infection. Optimal therapy requires a multimodal approach that combines surgery with adjuvant treatments. This review focuses on the use of adjunctive hyperbaric oxygen therapy for this condition. In addition to evidence regarding the basic and clinical science behind hyperbaric oxygen therapy, controversies in the field and economic implications are discussed.
authors.affiliation: Hyperbaric Division, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.|Royal Canadian Medical Service, Canadian Armed Forces, Ottawa, ON, Canada.
authors.forename: P
authors.identifier: http://orcid.org/0000-0002-6581-983X
authors.initials: P
authors.lastname: Ceponis
authors.affiliation: Hyperbaric Division, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
authors.forename: C
authors.initials: C
authors.lastname: Keilman
authors.affiliation: Hyperbaric Division, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
authors.forename: C
authors.initials: C
authors.lastname: Guerry
authors.affiliation: Hyperbaric Division, Department of Anesthesiology, Duke University Medical Center, Durham, NC, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Freiberger
mesh_terms: D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000191:economics / Q000628:therapy*; D006801:Humans; D006931:Hyperbaric Oxygenation; D007568:Jaw; D010020:Osteonecrosis / Q000209:etiology / Q000628:therapy; D010025:Osteoradionecrosis / Q000191:economics / Q000628:therapy*
keywords: hyperbaric oxygen; osteonecrosis; therapies; wound healing