title: A FeCl3-catalyzed highly regioselective 1,2-addition/substitution sequence for the construction of coumarin-substituted bis(indolyl)methanes.
abstract: A FeCl3-catalyzed highly regioselective 1,2-addition/substitution sequence of 3-acetylcoumarins and indoles has been developed to afford highly hindered tetrasubstituted bis(indolyl)methanes bearing a biologically useful coumarin motif in 56-99% yields.
authors.affiliation: College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China. wangqilin@henu.edu.cn buzhanwei@henu.edu.cn.
authors.forename: Wen-Bo
authors.initials: WB
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China. wangqilin@henu.edu.cn buzhanwei@henu.edu.cn.
authors.forename: Yan-Shuo
authors.initials: YS
authors.lastname: Zhu
authors.affiliation: College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China. wangqilin@henu.edu.cn buzhanwei@henu.edu.cn.
authors.forename: Sheng-Qiang
authors.initials: SQ
authors.lastname: Guo
authors.affiliation: College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China. wangqilin@henu.edu.cn buzhanwei@henu.edu.cn.
authors.forename: Qi-Lin
authors.initials: QL
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, China. wangqilin@henu.edu.cn buzhanwei@henu.edu.cn.
authors.forename: Zhan-Wei
authors.initials: ZW
authors.lastname: Bu
mesh_terms: D002384:Catalysis; D002712:Chlorides / Q000737:chemistry*; D003374:Coumarins / Q000737:chemistry*; D005290:Ferric Compounds / Q000737:chemistry*; D007211:Indoles / Q000737:chemistry*; D008697:Methane / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D002712:Chlorides; D003374:Coumarins; D005290:Ferric Compounds; D007211:Indoles; C030123:coumarin; D008697:Methane; C024555:ferric chloride