title: [Role of bacteriobilia in postoperative complications].
abstract: OBJECTIVE
  At present there is a controversy regarding the impact of positive bile cultures on morbidity and mortality rates, and on the incidence of readmissions in patients with biliar disease. The aim of this study was to evaluate the role of bacteriobilia in postoperatory infections, mortality or readmissions in these patients.
  
  
  METHODS
  The information was obtained from all patients with bile cultures admitted to Hospital Universitario Marqués de Valdecilla (Santander, Spain) from January to December 2011. Clinical, epidemiological and microbiological data and laboratory findings were analyzed. The patients were followed for two years.
  
  
  RESULTS
  One hundred and fifty-two patients (65% men) were included. Mean age was 67 years (SD= 15 years). The most frequent diagnoses were acute cholecystitis (79%) and cholangitis (8%). Laparoscopic cholecystectomy was performed in 42% of patients, open cholecystectomy in 45% and percutaneous cholecystostomy in 8%. Bacteriobilia was present in 83 patients (55%). The most frecuent microorganisms isolated were Escherichia coli (31%), Enterococcus faecium (13%) and Klebsiella pneumoniae (13%). The initial antimicrobial agent was a carbapenem in 62 patients (44%) and piperacillin-tazobactam in 28 (18%). There were 39 postoperative infections (26%), 21 readmissions (14%) and 17 patients died during admission (11%). The presence of microorganisms in bile cultures was not a statistically significant predictor of neither complications nor readmissions.
  
  
  CONCLUSIONS
  Intra-operative bile cultures would allow guide early appropriate antibiotic treatment use in case of infection, or empiric antimicrobial therapy, however there was no correlation between bacteriobilia and postoperative infections, length of stay, mortality or readmissions.
authors.forename: C
authors.initials: C
authors.lastname: Armiñanzas
authors.forename: T
authors.initials: T
authors.lastname: Tigera
authors.forename: D
authors.initials: D
authors.lastname: Ferrer
authors.forename: J
authors.initials: J
authors.lastname: Calvo
authors.forename: L A
authors.initials: LA
authors.lastname: Herrera
authors.forename: M
authors.initials: M
authors.lastname: Pajarón
authors.forename: M
authors.initials: M
authors.lastname: Gómez-Fleitas
authors.affiliation: M. Carmen Fariñas, Sección de Enfermedades Infecciosas. Hospital Universitario Marqués de Valdecilla Universidad de Cantabria. Av. Valdecilla s/n 39008, Santander, Spain. mcfarinas@humv.es.
authors.forename: M C
authors.initials: MC
authors.lastname: Fariñas
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000150:complications / Q000382:microbiology* / Q000401:mortality; D001646:Bile / Q000382:microbiology; D001649:Bile Duct Diseases / Q000150:complications / Q000382:microbiology* / Q000401:mortality; D002761:Cholangitis / Q000601:surgery; D002763:Cholecystectomy; D017081:Cholecystectomy, Laparoscopic; D002764:Cholecystitis / Q000601:surgery; D002767:Cholecystostomy; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010359:Patient Readmission / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000382:microbiology* / Q000401:mortality; D011379:Prognosis
chemical_list: D000900:Anti-Bacterial Agents