title: A Mild and General One-Pot Synthesis of Densely Functionalized Diaryliodonium Salts.
abstract: Diaryliodonium salts are powerful and widely used arylating agents in organic chemistry. Here we report a scalable, synthesis of densely functionalized diaryliodonium salts from aryl iodides under mild conditions. This two-step, one-pot process has remarkable functional group tolerance, is compatible with commonly employed acid-labile protective group strategies, avoids heavy metal and transition metal reagents, and provides a direct route to stable precursors to PET imaging agents.
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Linlin
authors.initials: L
authors.lastname: Qin
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group; Institute of Industrial Catalysis, College of Chemical Engineering, Zhejiang University of Technology, Hangzhou, Zhejiang 310014 (China).
authors.forename: Bao
authors.initials: B
authors.lastname: Hu
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Kiel D
authors.initials: KD
authors.lastname: Neumann
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Ethan J
authors.initials: EJ
authors.lastname: Linstad
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Katelyenn
authors.initials: K
authors.lastname: McCauley
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Jordan
authors.initials: J
authors.lastname: Veness
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Jayson J
authors.initials: JJ
authors.lastname: Kempinger
authors.affiliation: Department of Chemistry & Nebraska Center for Materials and Nanoscience, University of Nebraska, Lincoln, Nebraska 68588-0304 (USA), http://chem.unl.edu/dimagno-group.
authors.forename: Stephen G
authors.initials: SG
authors.lastname: DiMagno
keywords: Selectfluor™; aryl iodides; diaryliodonium salts; iodane synthesis; oxidation