title: [Hypervitaminosis D due to a dietary supplement].
abstract: In the Netherlands, over-the-counter dietary supplements are controlled by the NVWA (Netherlands Food and Consumer Product Safety Authority). Nevertheless, health problems may ensue from the use of these freely available supplements. We describe the case of a 39-year-old woman with a four-week history of headaches, nausea, reduced appetite and weight loss. Laboratory results showed severe hypercalcemia and impaired kidney function. An isolated increased vitamin D level was shown to be the cause. Although initial drug-taking history was negative, it appeared our patient had consumed a concentrated vitamin D supplement, supplied by a naturopath. The vitamin D concentration of the contents of this specific flacon proved to be 78 times higher than stated on the label. Consumers must be aware of the potential health risks posed by over-the-counter dietary supplements. We appeal to GPs, medical specialists and pharmacists to report these kinds of intoxications, allowing relevant authorities to subject the associated companies to adequate control measures.
authors.affiliation: Erasmus MC, afd. Huisartsgeneeskunde, Rotterdam.
authors.forename: Maaike
authors.initials: M
authors.lastname: Zigenhorn
authors.forename: Elsbeth M
authors.initials: EM
authors.lastname: Westerman
authors.forename: Arie P
authors.initials: AP
authors.lastname: Rietveld
mesh_terms: D000328:Adult; D019587:Dietary Supplements / Q000009:adverse effects*; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D006934:Hypercalcemia / Q000139:chemically induced* / Q000209:etiology; D009426:Netherlands; D004366:Nonprescription Drugs; D051437:Renal Insufficiency / Q000139:chemically induced*; D014807:Vitamin D / Q000008:administration & dosage / Q000009:adverse effects*
chemical_list: D004366:Nonprescription Drugs; D014807:Vitamin D