title: Glutathione S-transferase in the midgut tissue of gypsy moth (Lymantria dispar) caterpillars exposed to dietary cadmium.
abstract: Activity of glutathione S-transferase (GST) in midgut of gypsy moth caterpillars exposed to 10 and 30μg Cd/g dry food was examined. Based on the enzyme reaction through conjugation with glutathione, overall activity remained unaltered after acute and chronic treatment. No-observed-effect-concentration (10μg Cd/g dry food) significantly increased activity only after 3-day recovery following cadmium administration. Almost all comparisons of the indices of phenotypic plasticity revealed statistically significant differences. Despite the facts that GST has important role in xenobiotic biotransformation, our results indicate that this enzyme in insect midgut does not represent the key factor in cadmium detoxification.
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia. Electronic address: minavl@ibiss.bg.ac.rs.
authors.forename: Milena
authors.initials: M
authors.lastname: Vlahović
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia.
authors.forename: Larisa
authors.initials: L
authors.lastname: Ilijin
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia.
authors.forename: Marija
authors.initials: M
authors.lastname: Mrdaković
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia.
authors.forename: Dajana
authors.initials: D
authors.lastname: Todorović
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia.
authors.forename: Dragana
authors.initials: D
authors.lastname: Matić
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia.
authors.forename: Jelica
authors.initials: J
authors.lastname: Lazarević
authors.affiliation: Department of Insect Physiology and Biochemistry, Institute for Biological Research "Siniša Stanković", Despot Stefan Blvd. 142, University of Belgrade, Serbia.
authors.forename: Vesna Perić
authors.initials: VP
authors.lastname: Mataruga
mesh_terms: D000818:Animals; D002104:Cadmium / Q000494:pharmacology*; D004032:Diet; D004064:Digestive System / Q000187:drug effects* / Q000201:enzymology; D005982:Glutathione Transferase / Q000378:metabolism*; D007814:Larva / Q000187:drug effects* / Q000201:enzymology; D009036:Moths / Q000187:drug effects* / Q000201:enzymology
chemical_list: D002104:Cadmium; D005982:Glutathione Transferase
keywords: Dietary cadmium; Glutathione S-transferase; Gypsy moth; Midgut