title: Serum haptoglobin and C-reactive protein concentration in relation to rectal and vaginal temperature of early postpartum sows.
abstract: Various attempts were made to improve the diagnosis of the periparturient hypogalactia syndrome in sows. A new approach was the detection of elevated concentrations of acute phase proteins. The objective of our study was to investigate the serum concentrations of haptoglobin (Hp) and C-reactive protein (CRP) in sows on Day 7 postpartum and relationship to body temperature. From Day 1 to Day 6 postpartum, 199 sows were clinically examined and a blood sample was taken for measuring Hp and CRP at Day 7. The median of Hp and CRP were 1.83 mg/mL (interquartile range: 1.42-2.13 mg/mL) and 60.0 μg/mL (interquartile range: 15.2-216.5 μg/mL). We did not find a correlation between Hp and CRP (ρ = 0.11, P = 0.12) nor a difference between sows categorized as ill and healthy sows in Hp concentration (P = 0.1) and CRP (P = 0.34). Sows with Hp > 2.13 mg/mL had a higher rectal temperature than sows with Hp ≤ 2.13 mg/mL (P = 0.037), but there was no difference in vaginal temperature (P = 0.24). Regarding CRP, sows with CRP greater than 216.5 μg/mL had higher rectal temperature (P = 0.017) and vaginal temperature (P = 0.02) than sows with CRP ≤ 216.5 μg/mL. As demonstrated in this study, Hp and CRP do not support the detection of early postpartum disorders in sows.
authors.affiliation: Clinic of Animal Reproduction, Faculty of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany; Tierärztliche Praxis Am Weinberg, Jessen, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Stiehler
authors.affiliation: Clinic of Animal Reproduction, Faculty of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany. Electronic address: w.heuwieser@fu-berlin.de.
authors.forename: W
authors.initials: W
authors.lastname: Heuwieser
authors.affiliation: Tierärztliche Praxis Am Weinberg, Jessen, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Pfützner
authors.affiliation: Clinic of Animal Reproduction, Faculty of Veterinary Medicine, Freie Universität Berlin, Berlin, Germany.
authors.forename: O
authors.initials: O
authors.lastname: Burfeind
mesh_terms: D000818:Animals; D001831:Body Temperature / Q000502:physiology*; D002097:C-Reactive Protein / Q000378:metabolism*; D005260:Female; D006242:Haptoglobins / Q000378:metabolism*; D049590:Postpartum Period / Q000097:blood* / Q000502:physiology; D012007:Rectum; D013552:Swine / Q000097:blood* / Q000502:physiology; D014621:Vagina
chemical_list: D006242:Haptoglobins; D002097:C-Reactive Protein
keywords: Acute phase protein; Body temperature; Periparturient hypogalactia syndrome; Postpartum period; Sow