title: Prognostic significance of whole blood viscosity estimated by de Simone's formula in ST-elevation myocardial infarction.
abstract: We assessed the predictive value of estimated whole blood viscosity (WBV) in-hospital and long-term cardiovascular outcomes in patients with ST-elevation myocardial infarction (STEMI).
  
  
  
  One thousand eight hundred and thirty-five STEMI patients were followed up for median 34.6 months. WBV was calculated consistent with the de Simone's formula.
  
  
  
  In-hospital and long-term major adverse cardiovascular events (MACE) demonstrated an incremental trend in ascending order of WBV tertiles at low and high shear rate. Kaplan-Meier analysis showed a higher occurrence of long-term MACE in third WBV tertiles compared with other tertiles.
  
  
  
  WBV seems to be a feasible prognostic indicator of short- and long-term cardiovascular adverse events in patients with STEMI. As an easily available parameter, WBV may be utilized in identifying high-risk patients for subsequent MACE.
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Elif Hande Ozcan
authors.initials: EH
authors.lastname: Cetin
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Mehmet Serkan
authors.initials: MS
authors.lastname: Cetin
authors.affiliation: Cardiology Department, Hacettepe University, Ankara, Turkey.
authors.forename: Uğur
authors.initials: U
authors.lastname: Canpolat
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Selahattin
authors.initials: S
authors.lastname: Aydin
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Dursun
authors.initials: D
authors.lastname: Aras
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Topaloglu
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Temizhan
authors.affiliation: Cardiology Department, Turkey Yuksek Ihtisas Training & Research Hospital, Ankara, Turkey.
authors.forename: Sinan
authors.initials: S
authors.lastname: Aydogdu
mesh_terms: D000368:Aged; D000465:Algorithms; D019540:Area Under Curve; D001809:Blood Viscosity / Q000502:physiology*; D017023:Coronary Angiography; D004452:Echocardiography; D005260:Female; D005500:Follow-Up Studies; D006760:Hospitalization; D006801:Humans; D053208:Kaplan-Meier Estimate; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D016016:Proportional Hazards Models; D012372:ROC Curve; D000072657:ST Elevation Myocardial Infarction / Q000175:diagnosis* / Q000401:mortality / Q000473:pathology; D012680:Sensitivity and Specificity; D033081:Shear Strength; D013997:Time Factors
keywords: MACE; ST-elevation myocardial infarction; shear rate; whole blood viscosity