title: A High-Quality Biobank Supports Breast Cancer Research in Harbin, China.
abstract: We established a standard breast cancer biobank at Harbin Medical University Cancer Hospital (HMUCH) in 2009. More than 100,000 biospecimens, including high-quality human breast cancer samples, matched blood samples, and adjacent normal tissues, were collected from patients and healthy donors in HMUCH and were then deposited in the repository. We reported the establishment of a biobank in our hospital and its crucial role in translational medicine research. We stored, processed, and distributed qualified biological specimens in accordance with international standard operating procedures. We also summarized the utilization of this biobank and its influence on research projects over the years since its establishment. Therefore, we can verify specific biomarkers that may aid in the development of targeted breast cancer therapies by using high-quality, well-annotated tissue samples provided by the biobank.
authors.affiliation: 1 Breast Cancer Biobank, Harbin Medical University Cancer Hospital, Harbin, China .
authors.forename: Guangwen
authors.initials: G
authors.lastname: Zhang
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .|3 Center for Infectious and Inflammatory Diseases at Institute of Biosciences and Technology, Texas A&M University Health Science Center , Houston, Texas.
authors.forename: Bingshu
authors.initials: B
authors.lastname: Xia
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .
authors.forename: Tong
authors.initials: T
authors.lastname: Liu
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .
authors.forename: Jinfeng
authors.initials: J
authors.lastname: Zhang
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .
authors.forename: Ming
authors.initials: M
authors.lastname: Niu
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .
authors.forename: Shouping
authors.initials: S
authors.lastname: Xu
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .
authors.forename: Xianan
authors.initials: X
authors.lastname: Bai
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .
authors.forename: Zilong
authors.initials: Z
authors.lastname: You
authors.affiliation: 1 Breast Cancer Biobank, Harbin Medical University Cancer Hospital, Harbin, China .
authors.forename: Qiuju
authors.initials: Q
authors.lastname: Xu
authors.affiliation: 1 Breast Cancer Biobank, Harbin Medical University Cancer Hospital, Harbin, China .
authors.forename: Yin
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: 3 Center for Infectious and Inflammatory Diseases at Institute of Biosciences and Technology, Texas A&M University Health Science Center , Houston, Texas.|4 College of Medicine, Texas A&M University Health Science Center , Houston, Texas.
authors.forename: Joseph
authors.initials: J
authors.lastname: Cleveland
authors.affiliation: 2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .|3 Center for Infectious and Inflammatory Diseases at Institute of Biosciences and Technology, Texas A&M University Health Science Center , Houston, Texas.
authors.forename: Dekai
authors.initials: D
authors.lastname: Zhang
authors.affiliation: 1 Breast Cancer Biobank, Harbin Medical University Cancer Hospital, Harbin, China .|2 Department of Breast Surgery, The Third Affiliated Hospital of Harbin Medical University, Harbin, China .|5 Tumor Research Institute, Heilongjiang Medical Science Institute, Harbin, China .
authors.forename: Da
authors.initials: D
authors.lastname: Pang
mesh_terms: D014408:Biomarkers, Tumor / Q000378:metabolism; D035843:Biomedical Research; D001943:Breast Neoplasms / Q000235:genetics / Q000378:metabolism / Q000473:pathology; D005260:Female; D006801:Humans; D012313:RNA / Q000302:isolation & purification / Q000592:standards; D013048:Specimen Handling / Q000592:standards*; D014015:Tissue Banks / Q000592:standards*; D059467:Transcriptome; D057170:Translational Research, Biomedical
chemical_list: D014408:Biomarkers, Tumor; D012313:RNA
keywords: biobank; breast cancer; high-quality samples; storage conditions