title: Somatostatin Analog Therapy in Small Cell Lung Cancer.
abstract: Chemotherapy represents the cornerstone of treatment for patients with small cell lung cancer (SCLC); however, standard therapy has reached a plateau in improving patient survival with overall disappointing results. The demonstration that SCLC expresses neuroendocrine markers, such as somatostatin (SST) receptors, has led to use SST analogs or radiolabeled SST analogs in the treatment of SCLC patients. In the current review, we would focus on the possible role of SST analogs in SCLC.
authors.affiliation: Unit of Medical Oncology, Department of Onco-Hematology, IRCCS, Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture, PZ, Italy. Electronic address: tarta1@virgilio.it.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Tartarone
authors.affiliation: Hospital Pharmacy, Department of Onco-Hematology, IRCCS, Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture, PZ, Italy.
authors.forename: Rosa
authors.initials: R
authors.lastname: Lerose
authors.affiliation: Unit of Medical Oncology, Department of Onco-Hematology, IRCCS, Centro di Riferimento Oncologico della Basilicata, Rionero in Vulture, PZ, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Aieta
mesh_terms: D000818:Animals; D006801:Humans; D008175:Lung Neoplasms / Q000188:drug therapy / Q000378:metabolism / Q000532:radiotherapy / Q000628:therapy*; D017481:Receptors, Somatostatin / Q000378:metabolism; D055752:Small Cell Lung Carcinoma / Q000188:drug therapy / Q000378:metabolism / Q000532:radiotherapy / Q000628:therapy*; D013004:Somatostatin / Q000031:analogs & derivatives* / Q000378:metabolism / Q000627:therapeutic use*
chemical_list: D017481:Receptors, Somatostatin; D013004:Somatostatin