title: New Approaches for Controlling Saprolegnia parasitica, the Causal Agent of a Devastating Fish Disease.
abstract: Pathogenic oomycetes have the ability to infect a wide range of plant and animal hosts and are responsible for a number of economically important diseases. Saprolegniasis, a disease affecting fish eggs and juvenile fish in hatcheries worldwide, is caused by the pathogenic oomycete Saprolegnia parasitica. This disease presents as greyish-white patches of filamentous mycelium on the body or fins of fish and is associated with tissue damage leading to death of the animal. Traditionally, saprolegniasis was controlled using Malachite green; however, this chemical was banned in 2002 due to its carcinogenic and toxicological effects. As a direct result of this ban, there has been a recent resurgence of saprolegniasis in the aquaculture industry, leading to economic losses world-wide. Hence, there is an urgent need to find alternative methods to control this pathogen. We discuss the use of molecular approaches for the study of saprolegniasis, which are anticipated to enable the development of effective fish vaccines and the potential for the development of new methods to control this devastating disease.
authors.affiliation: Department of Biology, University of Victoria, PO Box 3020 STN CSC, Victoria, BC V8W 3N5, Canada.
authors.forename: Gregory
authors.initials: G
authors.lastname: Earle
authors.affiliation: Department of Biology, University of Victoria, PO Box 3020 STN CSC, Victoria, BC V8W 3N5, Canada.
authors.forename: William
authors.initials: W
authors.lastname: Hintz
keywords: Oomycete; Pathology; Saprolegnia parasitica; Saprolegniasis