title: The Characteristics of Staphylococcus aureus Small Colony Variant Isolated from Chronic Mastitis at a Dairy Farm in Yunnan Province, China.
abstract: Staphylococcus aureus is a major causative agent leading to bovine mastitis and has specific phonotypical characteristics including small colony, slow growth, and decreased hemolysis, therefore named as the small colony variants (SCVs). Out of 30 tested samples of the chronic S. aureus cases, one strain of SCVs (S. aureus SCV22) was isolated along with its parental strains (S. aureus11). S. aureus SCV22 showed a slow growth rate when it is compared with the parental strain. However, their resistant patterns were similar. Meanwhile, S. aureus SCV22 depicted the lower rate of apoptosis in bovine mammary epithelial cells. These findings of the present study presented the unique characteristics of S. aureus SCV22 for the first time in Yunnan province, which provided a prophase foundation for further study about the pathogenesis of S. aureus SCVs in chronic mastitis.
authors.affiliation: Institute of Animal Science and Technology, Yunnan Agricultural University, Kunming 650051, China.
authors.forename: Li-li
authors.initials: LL
authors.lastname: Zhu
authors.affiliation: Institute of Animal Science and Technology, Yunnan Agricultural University, Kunming 650051, China.
authors.forename: Feng-cai
authors.initials: FC
authors.lastname: Zou
authors.affiliation: Institute of Animal Science and Technology, Yunnan Agricultural University, Kunming 650051, China.
authors.forename: Yu-lin
authors.initials: YL
authors.lastname: Yan
authors.affiliation: Institute of Animal Science and Technology, Yunnan Agricultural University, Kunming 650051, China.
authors.forename: Qi-hui
authors.initials: QH
authors.lastname: Wang
authors.affiliation: Institute of Animal Science and Technology, Yunnan Agricultural University, Kunming 650051, China.
authors.forename: Yong-qiang
authors.initials: YQ
authors.lastname: Shi
authors.affiliation: Institute of Animal Science and Technology, Yunnan Agricultural University, Kunming 650051, China.
authors.forename: Wei-jie
authors.initials: WJ
authors.lastname: Qu
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D017209:Apoptosis / Q000187:drug effects; D002417:Cattle; D002681:China; D015169:Colony Count, Microbial; D003612:Dairying; D005260:Female; D042541:Intracellular Space / Q000378:metabolism; D008414:Mastitis, Bovine / Q000382:microbiology*; D008826:Microbial Sensitivity Tests; D008892:Milk / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000254:growth & development* / Q000302:isolation & purification* / Q000648:ultrastructure
chemical_list: D000900:Anti-Bacterial Agents