title: [A co-twin control study on birth weight, overweight and obesity among children younger than 18 years old in China].
abstract: OBJECTIVE
  To analyze the associations between birth weight and overweight/obesity among children.
  
  
  METHODS
  A total of 8 267 twin pairs younger than 18 years old from the Chinese National Twin Registry were included in the study. Associations between birth weight, childhood BMI and overweight/obesity were explored by this co-twin control study.
  
  
  RESULTS
  After adjusting for sex and zygosity, when birth weight had an increase of 0.5 kg per fold, the OR values for overweight and obesity were 1.87(95%CI: 1.40-2.48) for 2-6 year olds, 1.69 (95%CI: 1.16-2.46) for 6-12 year olds and 1.28 (95%CI: 0.80-2.07) for 12-18 year olds.
  
  
  RESULTS
  from the stratified analysis in the 2-6 year-olds, statistically significant differences were seen. When birth weight increased 0.5 kg per fold, the risk of overweight and obesity increased by 0.87 times among the dizygotic twins, more than that of the monozygotic twins (OR=1.86, 95%CI:1.24-2.81). The risk for male twins was 1.12 times higher than that of female twins (OR=1.65, 95%CI:1.11-2.44).
  
  
  CONCLUSIONS
  Birth weight seemed associated with overweight and obesity for kids at early childhood or at age for schools. However, guidance on the implementation of public health interventions is still needed on these children.
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Canqing
authors.initials: C
authors.lastname: Yu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Wenjing
authors.initials: W
authors.lastname: Gao
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Weihua
authors.initials: W
authors.lastname: Cao
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Lyu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Shengfeng
authors.initials: S
authors.lastname: Wang
authors.affiliation: Qingdao Center for Disease Control and Prevention, Qingdao 266033, China.
authors.forename: Zengchang
authors.initials: Z
authors.lastname: Pang
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
authors.forename: Liming
authors.initials: L
authors.lastname: Cong
authors.affiliation: Department of Chronic and Non-communicable Disease Control and Prevention, Beijing Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: Zhong
authors.initials: Z
authors.lastname: Dong
authors.affiliation: Shanghai Center for Disease Control and Prevention, Shanghai 200336, China.
authors.forename: Fan
authors.initials: F
authors.lastname: Wu
authors.affiliation: Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.affiliation: Sichuan Provincial Center for Disease Control and Prevention, Chengdu 610041, China.
authors.forename: Xianping
authors.initials: X
authors.lastname: Wu
authors.affiliation: Department of Chronic and Non-communicable Disease Control and Prevention, Tianjin Center for Disease Control and Prevention, Tianjin 300011, China.
authors.forename: Dezheng
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Epidemiology, School of Public Health, Harbin Medical University, Harbin 150081, China.
authors.forename: Binyou
authors.initials: B
authors.lastname: Wang
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing 100191, China.
authors.forename: Liming
authors.initials: L
authors.lastname: Li
mesh_terms: D000293:Adolescent; D001724:Birth Weight; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000208:ethnology*; D050177:Overweight / Q000208:ethnology*; D012042:Registries; D012306:Risk; D014429:Twins, Dizygotic; D014430:Twins, Monozygotic