title: THink: Inferring Cognitive Status from Subtle Behaviors.
abstract: The Digital Clock Drawing Test is a fielded application that provides a major advance over existing neuropsychological testing technology. It captures and analyzes high precision information about both outcome and process, opening up the possibility of detecting subtle cognitive impairment even when test results appear superficially normal. We describe the design and development of the test, document the role of AI in its capabilities, and report on its use over the past seven years. We outline its potential implications for earlier detection and treatment of neurological disorders. We also set the work in the larger context of the THink project, which is exploring multiple approaches to determining cognitive status through the detection and analysis of subtle behaviors.
authors.affiliation: MIT CSAIL Cambridge, MA, davis@csail.mit.edu.
authors.forename: Randall
authors.initials: R
authors.lastname: Davis
authors.affiliation: Neurology Department Drexel College of Med., david.libon@drexelmed.edu.
authors.forename: David J
authors.initials: DJ
authors.lastname: Libon
authors.affiliation: Neurology Department Boston Univ Sch of Med, rhodaau@bu.edu.
authors.forename: Rhoda
authors.initials: R
authors.lastname: Au
authors.affiliation: MIT CSAIL Cambridge, MA, dpitman@ mit.edu.
authors.forename: David
authors.initials: D
authors.lastname: Pitman
authors.affiliation: Department of Neurology Lahey Health, dana.l.penney@lahey.org.
authors.forename: Dana L
authors.initials: DL
authors.lastname: Penney