title: Controlled DNA condensation and targeted cellular imaging by ligand exchange in a polysaccharide-quantum dot conjugate.
abstract: A multicomponent supramolecular nanoparticle composed of a polysaccharide-quantum dot conjugate was successfully constructed using a ligand-exchange method, which possessed low cellular cytotoxicity and showed controlled DNA condensation and targeted cellular imaging abilities toward cancer cells.
authors.affiliation: Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, Nankai University, Tianjin 300071, P. R. China. yuliu@nankai.edu.cn.
authors.forename: Yu-Hui
authors.initials: YH
authors.lastname: Zhang
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Zhang
authors.forename: Yang
authors.initials: Y
authors.lastname: Yang
authors.forename: Li-Xia
authors.initials: LX
authors.lastname: Chen
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
mesh_terms: D000818:Animals; D004247:DNA / Q000737:chemistry / Q000378:metabolism*; D000067493:Dynamic Light Scattering; D006801:Humans; D057927:Hydrophobic and Hydrophilic Interactions; D008024:Ligands; D061986:MCF-7 Cells; D051379:Mice; D018625:Microscopy, Atomic Force; D018613:Microscopy, Confocal; D046529:Microscopy, Electron, Transmission; D041681:NIH 3T3 Cells; D011134:Polysaccharides / Q000737:chemistry*; D045663:Quantum Dots / Q000737:chemistry*
chemical_list: D008024:Ligands; D011134:Polysaccharides; D004247:DNA