title: A convenient enantioselective CBS-reduction of arylketones in flow-microreactor systems.
abstract: A convenient, versatile, and green CBS-asymmetric reduction of aryl and heteroaryl ketones has been developed by using the microreactor technology. The study demonstrates that it is possible to handle borane solution safely within microreactors and that the reaction performs well using 2-MeTHF as a greener solvent.
authors.affiliation: Department of Pharmacy - Drug Sciences, University of Bari "A. Moro"; FLAME-Lab - Flow Chemistry and Microreactor Technology Laboratory, Via E. Orabona 4, I-70125, Italy. renzo.luisi@uniba.it leonardo.degennaro@uniba.it.
authors.forename: Sonia
authors.initials: S
authors.lastname: De Angelis
authors.affiliation: Department of Pharmacy - Drug Sciences, University of Bari "A. Moro"; FLAME-Lab - Flow Chemistry and Microreactor Technology Laboratory, Via E. Orabona 4, I-70125, Italy. renzo.luisi@uniba.it leonardo.degennaro@uniba.it.
authors.forename: Maddalena
authors.initials: M
authors.lastname: De Renzo
authors.affiliation: Department of Pharmacy - Drug Sciences, University of Bari "A. Moro"; FLAME-Lab - Flow Chemistry and Microreactor Technology Laboratory, Via E. Orabona 4, I-70125, Italy. renzo.luisi@uniba.it leonardo.degennaro@uniba.it.
authors.forename: Claudia
authors.initials: C
authors.lastname: Carlucci
authors.affiliation: Department of Pharmacy - Drug Sciences, University of Bari "A. Moro"; FLAME-Lab - Flow Chemistry and Microreactor Technology Laboratory, Via E. Orabona 4, I-70125, Italy. renzo.luisi@uniba.it leonardo.degennaro@uniba.it.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Degennaro
authors.affiliation: Department of Pharmacy - Drug Sciences, University of Bari "A. Moro"; FLAME-Lab - Flow Chemistry and Microreactor Technology Laboratory, Via E. Orabona 4, I-70125, Italy. renzo.luisi@uniba.it leonardo.degennaro@uniba.it.
authors.forename: Renzo
authors.initials: R
authors.lastname: Luisi