title: Factors predicting contralateral hematoma growth after unilateral drainage of bilateral chronic subdural hematoma.
abstract: OBJECTIVE Chronic subdural hematoma (CSDH) is a common form of intracranial hemorrhage with a recurrence rate of 9.2%-26.5% after bur hole surgery. Occasionally patients with bilateral CSDH undergo unilateral surgery because the contralateral hematoma is deemed to be asymptomatic, and in some of these patients the contralateral hematoma may subsequently enlarge, requiring additional surgery. The authors investigated the factors related to the growth of these hematomas. METHODS Ninety-three patients with bilateral CSDH who underwent unilateral bur hole surgery at Aizu Chuo Hospital were included in a retrospective analysis. Findings on preoperative MRI, preoperative thickness of the drained hematoma, and the influence of antiplatelet or anticoagulant drugs were considered and evaluated in univariate and multivariate analyses. RESULTS The overall growth rate was 19% (18 of 93 hematomas), and a significantly greater percentage of the hematomas that were iso- or hypointense on preoperative T1-weighted imaging showed growth compared with other hematomas (35.4% vs 2.3%, p < 0.001). Multivariate logistic regression analysis showed that findings on preoperative T1-weighted MRI were the sole significant predictor of hematoma growth, and other factors such as antiplatelet or anticoagulant drug use, patient age, patient sex, thickness of the treated hematoma, and T2-weighted MRI findings were not significantly related to hematoma growth. The adjusted odds ratio for hematoma growth in the T1 isointense/hypointense group relative to the T1 hyperintense group was 25.12 (95% CI 3.89-51.58, p < 0.01). CONCLUSIONS The findings of preoperative MRI, namely T1-weighted sequences, may be useful in predicting the growth of hematomas that did not undergo bur hole surgery in patients with bilateral CSDH.
authors.affiliation: Department of Neurosurgery, Aizu Chuo Hospital, Aizuwakamatsu, Fukushima; and.
authors.forename: Shigeta
authors.initials: S
authors.lastname: Fujitani
authors.affiliation: Department of Neurosurgery, Showa General Hospital, Kodaira, Tokyo, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Ishikawa
authors.affiliation: Department of Neurosurgery, Aizu Chuo Hospital, Aizuwakamatsu, Fukushima; and.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Miura
authors.affiliation: Department of Neurosurgery, Aizu Chuo Hospital, Aizuwakamatsu, Fukushima; and.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Takeda
authors.affiliation: Department of Neurosurgery, Aizu Chuo Hospital, Aizuwakamatsu, Fukushima; and.
authors.forename: Haruo
authors.initials: H
authors.lastname: Goto
authors.affiliation: Department of Neurosurgery, Aizu Chuo Hospital, Aizuwakamatsu, Fukushima; and.
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Maeda
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging; D018450:Disease Progression; D004322:Drainage; D005260:Female; D020200:Hematoma, Subdural, Chronic / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D011300:Preoperative Care; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors
keywords: CSDH = chronic subdural hematoma; INR = international normalized ratio; antiplatelet and anticoagulant therapy; chronic subdural hematoma; magnetic resonance imaging; recurrence; trauma