title: Imaging Findings in Pediatric Posterior Reversible Encephalopathy Syndrome (PRES): 5 Years of Experience From a Tertiary Care Center in India.
abstract: This study sought to evaluate the radiological and clinical spectrum of posterior reversible encephalopathy syndrome (PRES) in pediatric population. A retrospective evaluation of the pediatric patients with posterior reversible encephalopathy syndrome seen over the last 5 years in the authors' hospital was done. The magnetic resonance imaging (MRI) findings were analyzed, and a review of literature was performed. Out of 32 pediatric patients of posterior reversible encephalopathy syndrome, 10 (31.25%) were males and 22 (68.75%) were females, with a mean age of 10.6 years. Renal disease (62.5%) was the most common primary disease, followed by chemotherapy for hemato-oncologic malignancies (15.6%). Hypertension was present in 81.2% of cases. Atypical MRI findings were seen in 62.5% cases. Frontal involvement was common and seen in 56% of the cases. Overall, MRI findings considered atypical in adults were found to be common in the series of pediatric posterior reversible encephalopathy syndrome. The understanding of the clinical settings and familiarity with radiological findings in pediatric posterior reversible encephalopathy syndrome patients is important to adequately treat these patients and to avoid misdiagnosis.
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh, India drvivekgupta.pgi@gmail.com.
authors.forename: Vivek
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Bhatia
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh, India.
authors.forename: Niranjan
authors.initials: N
authors.lastname: Khandelwal
authors.affiliation: Department of Radiodiagnosis, PGIMER, Chandigarh, India.
authors.forename: Paramjeet
authors.initials: P
authors.lastname: Singh
authors.affiliation: Department of Pediatric Neurology, PGIMER, Chandigarh, India.
authors.forename: Pratibha
authors.initials: P
authors.lastname: Singhi
mesh_terms: D000293:Adolescent; D001921:Brain / Q000000981:diagnostic imaging*; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007194:India; D008279:Magnetic Resonance Imaging; D008297:Male; D054038:Posterior Leukoencephalopathy Syndrome / Q000000981:diagnostic imaging* / Q000209:etiology / Q000503:physiopathology; D062606:Tertiary Care Centers
keywords: MRI; brain; pediatrics; posterior reversible encephalopathy syndrome (PRES); seizures