title: Zika virus: A new human teratogen? Implications for women of reproductive age.
abstract: In 2015 an unprecedented increase of reports of newborns with microcephaly in Brazil made news headlines around the world. A possible etiological association with prenatal maternal infection by Zika virus (ZIKV) was suggested based on temporal and geographic distribution of ZIKV infection and the subsequent increase in the reports of microcephaly cases. Here we discuss ZIKV as a new human teratogen, with comments on potential treatment options.
authors.affiliation: SIAT, Brazilian Teratogen Information Service, Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Brazil.|Post-Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Schuler-Faccini
authors.affiliation: SIAT, Brazilian Teratogen Information Service, Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Brazil.|Post-Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul, Brazil.
authors.forename: Mtv
authors.initials: M
authors.lastname: Sanseverino
authors.affiliation: SIAT, Brazilian Teratogen Information Service, Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Brazil.|Post-Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul, Brazil.
authors.forename: Fsl
authors.initials: F
authors.lastname: Vianna
authors.affiliation: SIAT, Brazilian Teratogen Information Service, Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Brazil.|UNIVATES University, Brazil.
authors.forename: A A
authors.initials: AA
authors.lastname: da Silva
authors.affiliation: SIAT, Brazilian Teratogen Information Service, Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Brazil.|Post-Graduate Program in Genetics and Molecular Biology, Federal University of Rio Grande do Sul, Brazil.
authors.forename: M
authors.initials: M
authors.lastname: Larrandaburu
authors.affiliation: Veterinary Sciences Faculty, UniRitter Laureate International Universities, Brazil.
authors.forename: C
authors.initials: C
authors.lastname: Marcolongo-Pereira
authors.affiliation: SIAT, Brazilian Teratogen Information Service, Medical Genetics Service, Hospital de Clinicas de Porto Alegre, Brazil.|Obstetrics and Gynecology Department, Federal University of Rio Grande do Sul, Brazil.
authors.forename: A M
authors.initials: AM
authors.lastname: Abeche
mesh_terms: D000818:Animals; D001938:Brazil / Q000453:epidemiology; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008831:Microcephaly / Q000453:epidemiology* / Q000821:virology; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000453:epidemiology* / Q000821:virology; D000071243:Zika Virus Infection / Q000150:complications* / Q000453:epidemiology / Q000628:therapy