title: Evaluation of furazolidone, sulfadimidine and amprolium to treat coccidiosis in Beetal goats under field conditions.
abstract: Coccidiosis is a protozoal and occasionally fatal diarrheic disease of goats imposing heavy economic losses to farming community. This study aimed to evaluate the efficacies of Furazolidone, Sulfadimidine and Amprolium against coccidiosis in Beetal goats. Twenty-four (24) Beetal goats naturally infected with coccidiosis were randomly divided into four groups of 6 (A-D). Goats in groups A, B and C were treated orally with Furazolidone (10 mg/Kg), Sulfadimidine (100 mg/Kg) and Amprolium (55 mg/Kg), respectively for 7 days. Goats in-group D served as positive control. Oocysts per gram (OPG) of feces counts of individual goats in each group were performed on Days; 0 (pre-treatment) 7, 14 and 21 (post-treatment). OPG counts amongst goats in all groups at day 0 were not significant (P>0.05). On days 7, 14 and 21, OPG values decreased significantly (P<0.05) in groups A, B and C compared to group D. The efficacy of Furazolidone, Sulfadimidine and Amprolium was 98.6, 98.0 and 99.6 percent, respectively on Day 21 (end of trial). Statistically, the efficacies of three drugs were not significantly different (P>0.05). In conclusion, Furazolidone, Sulfadimidine and Amprolium are well-tolerated and any one of these may be recommended to effectively treat coccidiosis in Beetal goats.
authors.affiliation: Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Avais
authors.affiliation: Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
authors.forename: Ghazanfar
authors.initials: G
authors.lastname: Rashid
authors.affiliation: Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Ijaz
authors.affiliation: Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
authors.forename: Muhammad Arif
authors.initials: MA
authors.lastname: Khan
authors.affiliation: Department of Clinical Sciences, College of Veterinary and Animal Sciences, Jhang, Pakistan.
authors.forename: Amar
authors.initials: A
authors.lastname: Nasir
authors.affiliation: Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
authors.forename: Muhammad Shoaib
authors.initials: MS
authors.lastname: Jahanzaib
authors.affiliation: Department of Clinical Medicine and Surgery, Faculty of Veterinary Science, University of Veterinary and Animal Sciences, Lahore, Pakistan.
authors.forename: Jawaria Ali
authors.initials: JA
authors.lastname: Khan
authors.affiliation: University College of Veterinary and Animal Sciences, Islamia University Bahawalpur, Pakistan.
authors.forename: Sajid
authors.initials: S
authors.lastname: Hameed
authors.affiliation: School of Animal and Veterinary Sciences, University of Adelaide, Roseworthy Campus, Roseworthy, Australia.
authors.forename: Michael Philipp
authors.initials: MP
authors.lastname: Reichel
mesh_terms: D000284:Administration, Oral; D000670:Amprolium / Q000008:administration & dosage / Q000627:therapeutic use*; D000818:Animals; D003048:Coccidiosis / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology / Q000662:veterinary*; D003049:Coccidiostats / Q000008:administration & dosage / Q000627:therapeutic use*; D005243:Feces / Q000469:parasitology; D005664:Furazolidone / Q000008:administration & dosage / Q000627:therapeutic use*; D015511:Goat Diseases / Q000175:diagnosis / Q000188:drug therapy* / Q000469:parasitology; D006041:Goats; D010154:Pakistan; D010270:Parasite Egg Count / Q000662:veterinary; D011897:Random Allocation; D013418:Sulfamethazine / Q000008:administration & dosage / Q000627:therapeutic use*; D013997:Time Factors; D016896:Treatment Outcome; D019155:Veterinary Drugs / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D003049:Coccidiostats; D019155:Veterinary Drugs; D013418:Sulfamethazine; D005664:Furazolidone; D000670:Amprolium