title: Jacob's disease: Report of a case.
abstract: OBJECTIVE
  Jacob's disease (JD) is an uncommon disorder that presents as pseudojoint formation between the enlarged mandibular coronoid process and the zygoma, resulting in mouth opening limitation (MOL). Intraosseous lipoma (IOL) usually presents in the long bone, but it is very rare in the mandible. The authors present a rare case of JD and coexisting IOL in the same anatomical area and discuss diagnosis and surgical intervention.
  
  
  METHODS
  The patient was a 39-year-old Korean female with MOL. Magnetic resonance imaging showed a large lobulated mass with fat-specific signal intensity. A combined extraoral and intraoral approach was used to resect the large mass. Histopathologic examination revealed a degenerated lipomatous tumor replacing the marrow cavity, with cartilaginous cap formation on the articular surface.
  
  
  CONCLUSIONS
  Postoperatively, the patient showed uneventful healing and resolution of MOL.
authors.affiliation: a Department of Oral and Maxillofacial Surgery, Section of Dentistry , Seoul Metropolitan Government - Seoul National University Boramae Medical Center , Seoul , Republic of Korea.
authors.forename: Dong-Whan
authors.initials: DW
authors.lastname: Shin
authors.affiliation: b Department of Pathology , Seoul National University College of Medicine , Seoul , Republic of Korea.
authors.forename: Ji-Eun
authors.initials: JE
authors.lastname: Kim
authors.affiliation: c Department of Conservative Dentistry, Section of Dentistry , Seoul Metropolitan Government - Seoul National University Boramae Medical Center , Seoul , Republic of Korea.
authors.forename: Hee-Sun
authors.initials: HS
authors.lastname: Kim
authors.affiliation: a Department of Oral and Maxillofacial Surgery, Section of Dentistry , Seoul Metropolitan Government - Seoul National University Boramae Medical Center , Seoul , Republic of Korea.
authors.forename: Ho
authors.initials: H
authors.lastname: Lee
mesh_terms: D000328:Adult; D044466:Asian People; D005260:Female; D006801:Humans; D006965:Hyperplasia; D008279:Magnetic Resonance Imaging / Q000379:methods; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D008336:Mandibular Diseases / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D015831:Osteochondroma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D016059:Range of Motion, Articular; D013705:Temporomandibular Joint Disorders / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000379:methods; D015050:Zygoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery
keywords: Intraosseous lipoma; Jacob’s disease; Mandibular coronoid process; Mouth opening limitation; Temporomandibular joint disorders