title: Comparison of Guided and Unguided Ocriplasmin Injection for the Treatment of Vitreomacular Traction: A Preliminary Study.
abstract: This retrospective quality control study aimed at comparing resolution in patients treated with intravitreal ocriplasmin (IVO) using two injection techniques, classical injection procedure (unguided) and targeted injection using a surgical microscope with a 30-gauge 1-inch needle (guided) for the treatment of focal VMT without macular hole. The two groups presented a statistically significant difference in terms of resolution of VMT within the first month following treatment: 1/7 for the unguided group versus 6/7 for the guided group (p = 0.0291). The majority of the guided group presented an earlier resolution than the single resolved case in the unguided group. The results of this preliminary study indicate that the injection of ocriplasmin closer to the site of VMT results in the resolution in a higher number of cases and that this resolution occurs in a short time interval.
authors.affiliation: Ophthalmology Unit, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona, 37100 Verona, Italy.
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Mastropasqua
authors.affiliation: Ophthalmology Clinic, Department of Medicine and Aging Science, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Di Antonio
authors.affiliation: Ophthalmology Clinic, Department of Medicine and Aging Science, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Ciciarelli
authors.affiliation: Ophthalmology Clinic, Department of Medicine and Aging Science, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
authors.forename: Agbeanda
authors.initials: A
authors.lastname: Aharrh-Gnama
authors.affiliation: Centro Oftalmologico Mediterraneo, 00195 Roma, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Rispoli
authors.affiliation: Ophthalmology Clinic, Department of Medicine and Aging Science, University "G. d'Annunzio" of Chieti-Pescara, 66100 Chieti, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Carpineto