title: Incidental Finding of a Neuroendocrine Tumor Arising from Meckel Diverticulum During Hernia Repair - A Case Report and Literature Review.
abstract: Meckel diverticulum is the most common abnormality of the gastrointestinal tract arising from an incomplete obliteration of the vitelline duct during the intrauterine life. Although tumor development in Meckel diverticulum is not a common situation, it can occur due to the persistence of cellular islets with gastric, pancreatic or intestinal origin. The presence of a neuroendocrine tumor arising from Meckel diverticulum is even scarcer. We present the case of a 59-year-old patient in whom a Meckel diverticulum was found during surgery for inguinal hernia; the histopathological and immunohistochemical studies revealed the presence of a well-differentiated neuroendocrine tumor with low mitotic index.
authors.affiliation: Carol Davila University of Medicine and Pharmacy, Bucharest, Romania nicolae_bacalbasa@yahoo.ro.
authors.forename: Nicolae
authors.initials: N
authors.lastname: Bacalbasa
authors.affiliation: Ilfov County Hospital, Bucharest, Romania.
authors.forename: Radu
authors.initials: R
authors.lastname: Costin
authors.affiliation: Fundeni Clinical Institute, Bucharest, Romania.
authors.forename: Carmen
authors.initials: C
authors.lastname: Orban
authors.affiliation: Fundeni Clinical Institute, Bucharest, Romania.
authors.forename: Laura
authors.initials: L
authors.lastname: Iliescu
authors.affiliation: Faculty of Economic Sciences and Public Administration, Stefan cel Mare University, Suceava, Romania.
authors.forename: Ioan
authors.initials: I
authors.lastname: Hurjui
authors.affiliation: Faculty of Economic Sciences and Public Administration, Stefan cel Mare University, Suceava, Romania.
authors.forename: Marcela
authors.initials: M
authors.lastname: Hurjui
authors.affiliation: Faculty of Entrepreneurship, Business Engineering and Management, University Politehnica, Bucharest, Romania.
authors.forename: Nicoleta
authors.initials: N
authors.lastname: Niculescu
authors.affiliation: Faculty of Economics and Business Administration, University of Craiova, Craiova, Romania.
authors.forename: Mirela
authors.initials: M
authors.lastname: Cristea
authors.affiliation: Ponderas Hospital, Bucharest, Romania.
authors.forename: Irina
authors.initials: I
authors.lastname: Balescu
mesh_terms: D053379:Chromogranin A / Q000378:metabolism; D006552:Hernia, Inguinal / Q000601:surgery*; D059685:Herniorrhaphy; D006801:Humans; D033162:Incidental Findings; D019394:Ki-67 Antigen / Q000378:metabolism; D008467:Meckel Diverticulum / Q000150:complications* / Q000473:pathology; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D017481:Receptors, Somatostatin / Q000378:metabolism; D016708:Synaptophysin / Q000378:metabolism
chemical_list: D053379:Chromogranin A; D019394:Ki-67 Antigen; D017481:Receptors, Somatostatin; C574734:SSTR2 protein, human; D016708:Synaptophysin; C094573:somatostatin receptor 5
keywords: Hernia; Meckel diverticulum; neuroendocrine tumor