title: Embolosclerotherapy by the Transvenous Approach for Lower Extremity Arteriovenous Malformation in Cowden Syndrome: A Case Report.
abstract: A 69-year-old female with Cowden syndrome presented with pain at rest in the right leg. Arteriovenous malformations (AVMs) of the right lower extremity were detected by computed tomography and magnetic resonance imaging. Angiography indicated arteriolovenous fistulae, which were initially treated using a transarterial approach with minimal therapeutic effect. In contrast, excellent outcomes were achieved with a transvenous approach using coil embolization and liquid sclerotherapy for the venous component of the nidus. At 15 months after embolosclerotherapy, no angiographic evidence of AVM recurrence was noted. Embolosclerotherapy by the transvenous approach for AVM in Cowden syndrome was a useful therapeutic strategy for arteriolovenous fistulae.
authors.affiliation: Department of Radiology, Saitama Cancer Center, Kitaadachi-gun, Saitama, Japan.
authors.forename: Akiyuki
authors.initials: A
authors.lastname: Matsuhisa
authors.affiliation: Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Kishino
authors.affiliation: Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Masashi
authors.initials: M
authors.lastname: Nakadate
authors.affiliation: Department of Surgery, Division of Vascular and Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Kudo
authors.affiliation: Department of Surgery, Division of Vascular and Endovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Inoue
authors.affiliation: Department of Radiology, Tokyo Medical and Dental University, Tokyo, Japan.
authors.forename: Ukihide
authors.initials: U
authors.lastname: Tateishi
keywords: Cowden syndrome; arteriovenous malformation; embolosclerotherapy