title: Sweet Mitochondrial Dynamics in VMH Neurons.
abstract: The ventromedial nucleus of the hypothalamus (VMH) is a central region known to maintain glucose homeostasis. Toda et al. (2016) unravel a new mechanism underlying VMH-dependent regulation of systemic glucose homeostasis via uncoupling protein 2 (UCP2)-mediated control of mitochondrial dynamics and activation of glucose-excited neurons.
authors.affiliation: Max-Planck-Institute for Metabolism Research, Gleueler Strasse 50a, 50931 Köln, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Ageing Associated Diseases (CECAD), Joseph-Stelzmann-Strasse 26, 50931 Köln, Germany; Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital, Joseph-Stelzmann-Strasse 26, 50931 Köln, Germany.
authors.forename: Sophie M
authors.initials: SM
authors.lastname: Steculorum
authors.affiliation: Max-Planck-Institute for Metabolism Research, Gleueler Strasse 50a, 50931 Köln, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Ageing Associated Diseases (CECAD), Joseph-Stelzmann-Strasse 26, 50931 Köln, Germany; Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital, Joseph-Stelzmann-Strasse 26, 50931 Köln, Germany. Electronic address: bruening@sf.mpg.de.
authors.forename: Jens C
authors.initials: JC
authors.lastname: Brüning
mesh_terms: D000818:Animals; D002467:Cell Nucleus / Q000378:metabolism*; D005947:Glucose / Q000378:metabolism*; D007473:Ion Channels / Q000378:metabolism*; D063154:Mitochondrial Dynamics; D024101:Mitochondrial Proteins / Q000378:metabolism*; D014697:Ventromedial Hypothalamic Nucleus / Q000378:metabolism*
chemical_list: D007473:Ion Channels; D024101:Mitochondrial Proteins; D005947:Glucose