title: Bowel preparation in "real-life" small bowel capsule endoscopy: a two-center experience.
abstract: BACKGROUND
  Video capsule endoscopy (VCE) is an established diagnostic tool for the investigation of small bowel (SB) pathology. Bowel preparation prior to VCE may improve visualization, transit time, and diagnostic yield. We aimed to evaluate the "real-life" experience comparing two different preparation protocols in patients undergoing SB VCE.
  
  
  METHODS
  We performed a retrospective analysis of prospectively collected data from SB VCE procedures, performed in two tertiary care medical centers in Israel. VCE procedures performed at "Sheba Medical Center" used a 2-L polyethylene glycol (PEG) bowel preparation (n=360) while VCEs performed at "Rambam Health Care campus" used a clear liquid diet plus 12-h fast protocol (n=500). A dichotomous preparation scale (adequate, inadequate) was used to classify cleansing quality. Data collection included patient and procedural details. The proportion of VCE procedures with adequate bowel preparation and the overall positive SB findings in the two different bowel preparation protocols were evaluated.
  
  
  RESULTS
  SB completion rates were higher in the PEG protocol (96% vs. 83%, P<0.001) and SB passage time was significantly faster in the PEG protocol (mean 217±73 vs. 238±77 min, P<0.001). Bowel preparation quality was similar between groups (8% vs. 7% inadequate preparation, P=0.591). Overall positive SB findings were similar between the two groups (57% clear liquid fasting only vs. 51% PEG protocol, P=0.119).
  
  
  CONCLUSIONS
  In this large cohort, a 2-L PEG protocol had similar preparation quality and diagnostic yield compared with clear liquid fasting.
authors.affiliation: Gastroenterology, Rambam Health Care Campus, Rappaport Family Faculty of Medicine Technion-Israel Institute of Technology, Haifa (Amir Klein, Marianna Dashkovsky, Ian Gralnek, Ravit Peled, Yehuda Chowers, Iyad Khamaysi), Tel-Aviv, Israel.
authors.forename: Amir
authors.initials: A
authors.lastname: Klein
authors.affiliation: Gastroenterology, Rambam Health Care Campus, Rappaport Family Faculty of Medicine Technion-Israel Institute of Technology, Haifa (Amir Klein, Marianna Dashkovsky, Ian Gralnek, Ravit Peled, Yehuda Chowers, Iyad Khamaysi), Tel-Aviv, Israel.
authors.forename: Marianna
authors.initials: M
authors.lastname: Dashkovsky
authors.affiliation: Gastroenterology, Rambam Health Care Campus, Rappaport Family Faculty of Medicine Technion-Israel Institute of Technology, Haifa (Amir Klein, Marianna Dashkovsky, Ian Gralnek, Ravit Peled, Yehuda Chowers, Iyad Khamaysi), Tel-Aviv, Israel.
authors.forename: Ian
authors.initials: I
authors.lastname: Gralnek
authors.affiliation: Gastroenterology, Rambam Health Care Campus, Rappaport Family Faculty of Medicine Technion-Israel Institute of Technology, Haifa (Amir Klein, Marianna Dashkovsky, Ian Gralnek, Ravit Peled, Yehuda Chowers, Iyad Khamaysi), Tel-Aviv, Israel.
authors.forename: Ravit
authors.initials: R
authors.lastname: Peled
authors.affiliation: Gastroenterology, Rambam Health Care Campus, Rappaport Family Faculty of Medicine Technion-Israel Institute of Technology, Haifa (Amir Klein, Marianna Dashkovsky, Ian Gralnek, Ravit Peled, Yehuda Chowers, Iyad Khamaysi), Tel-Aviv, Israel.
authors.forename: Yehuda
authors.initials: Y
authors.lastname: Chowers
authors.affiliation: Gastroenterology, Rambam Health Care Campus, Rappaport Family Faculty of Medicine Technion-Israel Institute of Technology, Haifa (Amir Klein, Marianna Dashkovsky, Ian Gralnek, Ravit Peled, Yehuda Chowers, Iyad Khamaysi), Tel-Aviv, Israel.
authors.forename: Iyad
authors.initials: I
authors.lastname: Khamaysi
authors.affiliation: Gastroenterology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv (Ofir Har-Noy, Idan Levi, Moshe Nadler, Rami Eliakim, Uri Kopylov), Tel-Aviv, Israel.
authors.forename: Ofir
authors.initials: O
authors.lastname: Har-Noy
authors.affiliation: Gastroenterology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv (Ofir Har-Noy, Idan Levi, Moshe Nadler, Rami Eliakim, Uri Kopylov), Tel-Aviv, Israel.
authors.forename: Idan
authors.initials: I
authors.lastname: Levi
authors.affiliation: Gastroenterology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv (Ofir Har-Noy, Idan Levi, Moshe Nadler, Rami Eliakim, Uri Kopylov), Tel-Aviv, Israel.
authors.forename: Moshe
authors.initials: M
authors.lastname: Nadler
authors.affiliation: Gastroenterology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv (Ofir Har-Noy, Idan Levi, Moshe Nadler, Rami Eliakim, Uri Kopylov), Tel-Aviv, Israel.
authors.forename: Rami
authors.initials: R
authors.lastname: Eliakim
authors.affiliation: Gastroenterology, Chaim Sheba Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv (Ofir Har-Noy, Idan Levi, Moshe Nadler, Rami Eliakim, Uri Kopylov), Tel-Aviv, Israel.
authors.forename: Uri
authors.initials: U
authors.lastname: Kopylov
keywords: Capsule endoscopy; bowel preparation; diagnostic yield; polyethylene glycol