title: A case of nosocomial Legionnaires' disease: The importance of early diagnosis, adequate prevention and eradication measures.
abstract: This case-report describes a patient with confirmed nosocomial Legionnaires' disease, a diagnosis which should be suspected when pneumonia does not respond to empiric therapy with beta-lactam antibiotics, or develops in the presence of certain risk factors. Culture is currently the golden standard for diagnosis, although the use of more modern techniques, such as a combination of urinary antigen testing and polymerase chain reaction, are on the rise. Specific detection and eradication methods are discussed.
authors.affiliation: a KU Leuven , Leuven , Belgium.
authors.forename: Alexander
authors.initials: A
authors.lastname: Lucardie
authors.affiliation: b Department of Pneumology , AZ Sint Lucas , Brugge , Belgium.
authors.forename: Philippe
authors.initials: P
authors.lastname: Rogiers
authors.affiliation: c Department of Microbiology , AZ Sint Lucas , Brugge , Belgium.
authors.forename: Katelijne Marie-José
authors.initials: KM
authors.lastname: Floré
keywords: Legionella PCR; Legionnaires’ disease; Nosocomial pneumonia; Water decontamination