title: Multidrug-resistant Combined Infections in a Liver Transplanted Patient: Case Report.
abstract: We report a case of successfully treated multiple liver abscesses in a liver-transplanted patient, sustained by combined multidrug-resistant infections. Two months after a liver transplant, a computed tomography scan revealed the presence of multiple abscesses in the liver graft. Blood cultures and abscessual liver fluid were both positive for acquired colistin- and carbapenem- resistant Klebsiella pneumoniae and an extended-spectrum of beta-lactamases-producing Enterobacter aerogenes. The treatment strategy consisted of different prolonged antimicrobial combinations and draining of the abscesses with complete recovery of the liver lesions.
authors.affiliation: Department of General Surgery and Odontoiatrics, Liver Transplant Unit, University Hospital of Verona, Verona, Italy, 37126.
authors.forename: Amedeo
authors.initials: A
authors.lastname: Carraro
authors.forename: Umberto
authors.initials: U
authors.lastname: Montin
authors.forename: Paola
authors.initials: P
authors.lastname: Violi
authors.forename: Fabio
authors.initials: F
authors.lastname: Soldani
authors.forename: Romualdo
authors.initials: R
authors.lastname: Mazzi
authors.forename: Mara
authors.initials: M
authors.lastname: Merighi
authors.forename: Faheem
authors.initials: F
authors.lastname: Kanani
authors.forename: Ercole
authors.initials: E
authors.lastname: Concia
authors.forename: Umberto
authors.initials: U
authors.lastname: Tedeschi
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D060085:Coinfection; D004322:Drainage; D024901:Drug Resistance, Multiple, Bacterial; D004359:Drug Therapy, Combination; D021902:Enterobacter aerogenes / Q000187:drug effects* / Q000302:isolation & purification; D004756:Enterobacteriaceae Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D007711:Klebsiella pneumoniae / Q000187:drug effects* / Q000302:isolation & purification; D008100:Liver Abscess / Q000175:diagnosis / Q000188:drug therapy* / Q000382:microbiology; D016031:Liver Transplantation / Q000009:adverse effects*; D008826:Microbial Sensitivity Tests; D000072078:Positron Emission Tomography Computed Tomography; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents