title: Cardiac troponin T and echocardiographic dimensions after repeated sprint vs. moderate intensity continuous exercise in healthy young males.
abstract: Regular physical exercise can positively influence cardiac function; however, investigations have shown an increase of myocardial damage biomarkers after acute prolonged endurance exercises. We investigated the effect of repeated sprint vs. moderate long duration exercise on markers of myocardial necrosis, as well as cardiac dimensions and functions. Thirteen healthy males performed two different running sessions (randomized, single blinded cross-over design): 60 minutes moderate intensity continuous training (MCT, at 70% of peak heart rate (HRpeak)) and two series of 12 × 30-second sprints with set recovery periods in-between (RST, at 90% HRpeak). Venous blood samples for cardiac troponin T (cTnT), creatine kinase (CK) and MB isoenzyme (CK-MB) were taken 1 and 4 hours after exercise sessions. After each session electrocardiographic (ECG) and transthoracic echocardiographic (TTE) data were recorded. Results showed that all variables - average heart rate, serum lactate concentration during RST, subjective exertion and cTnT after RST - were significantly higher compared to MCT. CK and CK-MB significantly increased regardless of exercise protocol, while ECG and TTE indicated normal cardiac function. Our results provide evidence that RST contributes significantly to cTnT and CK release. This biomarker increase seems to reflect a physiological rather than a pathological phenomenon in healthy, exercising subjects.
authors.affiliation: Institute of Sport Science, University of Rostock, Germany.|Institute of Exercise Physiology and Public Health, Rostock, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Weippert
authors.affiliation: Department of Cardiology, Campus Marburg, University Clinic Giessen and Marburg, Germany.
authors.forename: Dimitar
authors.initials: D
authors.lastname: Divchev
authors.affiliation: Department of Sports Medicine, Humboldt-University/Charité University Medicine, Berlin, Germany.
authors.forename: Paul
authors.initials: P
authors.lastname: Schmidt
authors.affiliation: Institute of Sport Science, University of Rostock, Germany.|Institute of Exercise Physiology and Public Health, Rostock, Germany.
authors.forename: Hannes
authors.initials: H
authors.lastname: Gettel
authors.affiliation: Department of Cardiology, Campus Marburg, University Clinic Giessen and Marburg, Germany.
authors.forename: Antina
authors.initials: A
authors.lastname: Neugebauer
authors.affiliation: Institute of Sport Science, University of Rostock, Germany.|Institute of Exercise Physiology and Public Health, Rostock, Germany.
authors.forename: Kristin
authors.initials: K
authors.lastname: Behrens
authors.affiliation: Department of Sports Medicine, Humboldt-University/Charité University Medicine, Berlin, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Wolfarth
authors.affiliation: Institute of Human Movement Science, University of Hamburg, Hamburg, Germany.
authors.forename: Klaus-Michael
authors.initials: KM
authors.lastname: Braumann
authors.affiliation: Department of Cardiology, Center for Internal Medicine, Rostock University Medicine, Rostock, Germany.
authors.forename: Christoph A
authors.initials: CA
authors.lastname: Nienaber
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D004452:Echocardiography; D004569:Electroencephalography; D015444:Exercise; D006321:Heart / Q000000981:diagnostic imaging* / Q000502:physiology; D006339:Heart Rate; D006801:Humans; D008297:Male; D020107:Troponin T / Q000097:blood*
chemical_list: D015415:Biomarkers; D020107:Troponin T