title: We Use Bioincompatible Peritoneal Dialysis Solutions.
abstract: Despite advances in peritoneal dialysis (PD) technique and therapy over the last 40 years, PD therapy for end-stage renal disease (ESRD) in the United States remains underutilized. One of the major factors contributing to this underutilization involves concerns about technique failure. More physiologic PD solutions, with a lower concentration of glucose degradation products and a neutral pH, exist and are readily available in Europe, Asia, and Australia. Several benefits of these biocompatible solutions exist over the conventional solutions including a slower decline in residual renal function and better maintenance of urine volumes. There may also be a beneficial effect of the biocompatible solutions in limiting the increase in peritoneal transport that is characteristic of patients maintained on conventional solutions. It should be of concern to the US nephrology community that biocompatible PD solutions are unavailable in the United States.
authors.affiliation: Department of Internal Medicine, Yale University, New Haven, Connecticut.
authors.forename: Laura
authors.initials: L
authors.lastname: Troidle
authors.affiliation: Department of Internal Medicine, Yale University, New Haven, Connecticut.
authors.forename: Joni
authors.initials: J
authors.lastname: Hansson
authors.affiliation: Department of Internal Medicine, Yale University, New Haven, Connecticut.
authors.forename: Peter
authors.initials: P
authors.lastname: Juergensen
authors.affiliation: Department of Internal Medicine, Yale University, New Haven, Connecticut.
authors.forename: Fredric O
authors.initials: FO
authors.lastname: Finkelstein
mesh_terms: D001672:Biocompatible Materials; D015314:Dialysis Solutions / Q000737:chemistry*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D009398:Nephrology / Q000379:methods*; D010530:Peritoneal Dialysis
chemical_list: D001672:Biocompatible Materials; D015314:Dialysis Solutions