title: Effect of ankaferd blood stopper in experimental peritoneal adhesion model.
abstract: OBJECTIVE
  Ankaferd Blood Stopper (ABS) is an herbal extract attained from 5 different plants. It has the therapeutic potential to be used for the management of external hemorrhage and controlling gastrointestinal bleedings. To date, the safety of ABS for intraperitoneal usage is not clear. In this study, we investigated the effectiveness and safety of using intraperitoneal ABS in an experimental peritoneal adhesion model.
  
  
  METHODS
  Twenty-four male Wistar Albino rats were used in the study. The rats were randomly divided into 3 groups: saline, ABS, and control. On the 10th day, all rats were euthanized. The adhesions were evaluated by Nair's macroscopic adhesion classification, and pathologically evaluated with Zühlke's microscopic adhesion classification.
  
  
  RESULTS
  macroscopic and microscopic comparison between the ABS and saline groups did not show any differences but both the ABS and saline groups were superior when compared to the control group.
  
  
  CONCLUSIONS
  ABS was found equally effective with saline on the abdominal adhesions and to no effect on postoperative adhesion formation.
authors.affiliation: Department of General Surgery, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Karaca
authors.affiliation: Department of General Surgery, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
authors.forename: Oktay
authors.initials: O
authors.lastname: Aydin
authors.affiliation: Department of General Surgery, Faculty of Medicine, Kırıkkale University, Kırıkkale, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Pehlivanli
authors.affiliation: Department of General Surgery, Ağrı State Hospital, Ağrı, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Kocael
authors.affiliation: Department of General Surgery, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Recep
authors.initials: R
authors.lastname: Pekcici
authors.affiliation: Department of General Surgery, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Esat
authors.initials: E
authors.lastname: Duymus
authors.affiliation: Department of Pathology, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Sukran
authors.initials: S
authors.lastname: Akgedik
authors.affiliation: Department of General Surgery, Ankara Education and Research Hospital, Ankara, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Guler
keywords: Ankaferd blood stopper; Intra-abdominal adhesion; Peritoneum; Rats