title: Ductal constriction during dexamethasone treatment in an anti-SSA-antibody-exposed fetus with signs of myocardial inflammation.
abstract: This report describes the clinical course and multi-modality imaging findings in an anti-SSA-antibody-exposed fetus with suspected myocardial inflammation. Postnatal cardiac MRI - using fast acquisition, free-breathing with feed-and-swaddle technique - was used to evaluate for myocardial fibrosis/inflammation. This is the first published report, to our knowledge, of ductal constriction temporally associated with oral dexamethasone therapy in an anti-SSA-antibody-exposed fetus and of the use of this unique postnatal MRI protocol in this setting.
authors.affiliation: Department of Cardiology,Children's National Medical Center,Washington,District of Columbia,United States of America.
authors.forename: Lauren
authors.initials: L
authors.lastname: Talemal
authors.affiliation: Department of Cardiology,Children's National Medical Center,Washington,District of Columbia,United States of America.
authors.forename: Laura
authors.initials: L
authors.lastname: Olivieri
authors.affiliation: Department of Cardiology,Children's National Medical Center,Washington,District of Columbia,United States of America.
authors.forename: Anita
authors.initials: A
authors.lastname: Krishnan
mesh_terms: D000328:Adult; D003251:Constriction, Pathologic / Q000139:chemically induced / Q000000981:diagnostic imaging; D003907:Dexamethasone / Q000009:adverse effects*; D004373:Ductus Arteriosus / Q000187:drug effects*; D004452:Echocardiography; D005260:Female; D005333:Fetus; D006801:Humans; D008279:Magnetic Resonance Imaging; D009205:Myocarditis / Q000139:chemically induced / Q000000981:diagnostic imaging*; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000503:physiopathology*; D012859:Sjogren's Syndrome / Q000188:drug therapy*
chemical_list: D003907:Dexamethasone
keywords: Anti-SSA antibodies; ductus arteriosus constriction; steroids