title: Video-Assisted Thoracoscopic Surgery Versus Thoracotomy Lymph Node Dissection in Clinical Stage I Lung Cancer: A Meta-Analysis and System Review.
abstract: Video-assisted thoracoscopic surgery (VATS) is the preferred surgical procedure, causing fewer injuries compared with thoracotomy, but whether VATS can achieve the same lymph node (LN) dissection efficacy is controversial. A systematic literature search was performed to identify studies comparing VATS and thoracotomy in LN dissection for clinical stage I lung cancer. Twenty articles met the inclusion criteria and involved 2,190 patients in the VATS group and 3,000 patients in the open group. Meta-analysis showed that fewer total LNs were dissected in the VATS group, although VATS harvested more left-side LNs. The same number of total LN stations, N2 LNs, N2 LN stations, N1 LNs, and right-side LNs was harvested in both groups. Our findings require further validation in more high-quality, large-scale randomized controlled trials.
authors.affiliation: Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
authors.forename: Wenxiong
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
authors.forename: Yiping
authors.initials: Y
authors.lastname: Wei
authors.affiliation: Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
authors.forename: Han
authors.initials: H
authors.lastname: Jiang
authors.affiliation: Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
authors.forename: Jianjun
authors.initials: J
authors.lastname: Xu
authors.affiliation: Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Nanchang University, Nanchang, China. Electronic address: yudongliang2015@163.com.
authors.forename: Dongliang
authors.initials: D
authors.lastname: Yu
mesh_terms: D000068598:Data Accuracy; D006801:Humans; D008175:Lung Neoplasms / Q000473:pathology / Q000601:surgery*; D008197:Lymph Node Excision / Q000379:methods*; D008207:Lymphatic Metastasis; D009367:Neoplasm Staging; D016032:Randomized Controlled Trials as Topic; D012189:Retrospective Studies; D020775:Thoracic Surgery, Video-Assisted; D013906:Thoracoscopy; D016896:Treatment Outcome