title: Primary adenocarcinoma of the seminal vesicles. A review of the literature.
abstract: Primary adenocarcinoma of the seminal vesicles (SV) are extremely rare and approximately only 60 cases have been reported in the literature. Due to the lack of specific symptoms the patients often present in an advanced stage of their disease. The only clinical examination that can indicate the presence of a neoplasm in the SVs is the digital rectal examination (DRE). Serum prostatic specific antigen (PSA) and prostate specific acid phosphatase (PAP) are usually normal in patients with primary adenocarcinoma of the SV and only CA-125 can be proved a useful blood biomarker contributing to the diagnosis and the follow up of the SV adenocarcinoma. Computed tomography (CT) and magnetic resonance imaging (MRI) and FDG-PET/CT have been used for the diagnosis and the staging of the SV adenocarcinoma. Various combinations of radical surgery, radiotherapy androgen deprivation therapy and chemotherapy have been proposed for the management of the disease but the prognosis is poor and the mean survival is two years after the diagnosis.
authors.affiliation: 1st University Urology Clinic Laiko Hospital, Athens. katafigiotis@yahoo.com.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Katafigiotis
authors.forename: Stavros
authors.initials: S
authors.lastname: Sfoungaristos
authors.forename: Mordechai
authors.initials: M
authors.lastname: Duvdevani
authors.forename: Panagiotis
authors.initials: P
authors.lastname: Mitsos
authors.forename: Eleni
authors.initials: E
authors.lastname: Roumelioti
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Stravodimos
authors.forename: Ioannis
authors.initials: I
authors.lastname: Anastasiou
authors.forename: Constantinos A
authors.initials: CA
authors.lastname: Constantinides
mesh_terms: D000230:Adenocarcinoma / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D018394:CA-125 Antigen / Q000097:blood; D005834:Genital Neoplasms, Male / Q000175:diagnosis / Q000473:pathology* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009367:Neoplasm Staging; D011379:Prognosis; D012669:Seminal Vesicles / Q000473:pathology*; D015996:Survival Rate; D014057:Tomography, X-Ray Computed
chemical_list: D018394:CA-125 Antigen