title: Topical timolol maleate 0.5% solution for the management of deep periocular infantile hemangiomas.
abstract: This retrospective, consecutive, clinical case series examined the use of topical timolol in the treatment of 5 children with deep, periocular infantile hemangiomas that caused astigmatism, change in head posture, or ptosis. All patients were treated with timolol maleate solution 0.5% twice daily until the lesions had regressed. All 5 children showed regression of the lesion and improvement in amblyogenic risk factors within 2 weeks.
authors.affiliation: Department of Pediatric Ophthalmology, Royal Berkshire Hospital, Reading, and King Edward VII Hospital, Windsor, United Kingdom. Electronic address: sallylpainter@cantab.net.
authors.forename: Sally L
authors.initials: SL
authors.lastname: Painter
authors.affiliation: Department of Pediatric Ophthalmology, Royal Berkshire Hospital, Reading, and King Edward VII Hospital, Windsor, United Kingdom.
authors.forename: Göran Darius
authors.initials: GD
authors.lastname: Hildebrand
mesh_terms: D000287:Administration, Topical; D000319:Adrenergic beta-Antagonists / Q000008:administration & dosage*; D000550:Amblyopia / Q000517:prevention & control; D005142:Eyelid Neoplasms / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D018324:Hemangioma, Capillary / Q000188:drug therapy* / Q000473:pathology; D006801:Humans; D007223:Infant; D008297:Male; D009386:Neoplastic Syndromes, Hereditary / Q000188:drug therapy* / Q000473:pathology; D009883:Ophthalmic Solutions; D009918:Orbital Neoplasms / Q000188:drug therapy* / Q000473:pathology; D012189:Retrospective Studies; D013999:Timolol / Q000008:administration & dosage*
chemical_list: D000319:Adrenergic beta-Antagonists; D009883:Ophthalmic Solutions; D013999:Timolol