title: Functional Agents to Biologically Control Deoxynivalenol Contamination in Cereal Grains.
abstract: Mycotoxins, as microbial secondary metabolites, frequently contaminate cereal grains and pose a serious threat to human and animal health around the globe. Deoxynivalenol (DON), a commonly detected Fusarium mycotoxin, has drawn utmost attention due to high exposure levels and contamination frequency in the food chain. Biological control is emerging as a promising technology for the management of DON contamination. Functional biological control agents (BCAs), which include antagonistic microbes, natural fungicides derived from plants and detoxification enzymes, can be used to control DON contamination at different stages of grain production. In this review, studies regarding different biological agents for DON control in recent years are summarized for the first time. Furthermore, this article highlights the significance of BCAs for controlling DON contamination, as well as the need for more practical and efficient BCAs concerning food safety.
authors.affiliation: SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Tian
authors.affiliation: SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
authors.forename: Yanglan
authors.initials: Y
authors.lastname: Tan
authors.affiliation: SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
authors.forename: Na
authors.initials: N
authors.lastname: Liu
authors.affiliation: College of Plant Science and Technology, Huazhong Agricultural University Wuhan, China.
authors.forename: Yucai
authors.initials: Y
authors.lastname: Liao
authors.affiliation: Academy of State Administration of Grain Beijing, China.
authors.forename: Changpo
authors.initials: C
authors.lastname: Sun
authors.affiliation: SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
authors.forename: Shuangxia
authors.initials: S
authors.lastname: Wang
authors.affiliation: SIBS-UGENT-SJTU Joint Laboratory of Mycotoxin Research, Key Laboratory of Food Safety Research, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences Shanghai, China.
authors.forename: Aibo
authors.initials: A
authors.lastname: Wu
keywords: Fusarium; biological agents; control; deoxynivalenol (DON); mycotoxin