title: Paget's Disease of Bone: Approach to Its Historical Origins.
abstract: Paget's disease of bone is the second most common bone disease after osteoporosis. It is characterized by focal regions of highly exaggerated bone remodeling, with abnormalities in all phases of the remodeling process. This study aims to investigate the hypothesis of a possible British origin of Paget's disease of bone by studying the worldwide geographic distribution of cases identified in ancient skeletons excavated from archaeological sites. The methodology consists in reviewing cases of Paget's disease of bone described in the literature.
authors.affiliation: Departamento de Prehistoria, Historia Antigua y Arqueología, Universidad de Salamanca, Salamanca, España. Electronic address: mbueyes@usal.es.
authors.forename: Luis R
authors.initials: LR
authors.lastname: Menéndez-Bueyes
authors.affiliation: Servicio de Medicina Interna, Complejo Asistencial de Zamora, Zamora, España.
authors.forename: María Del Carmen
authors.initials: MD
authors.lastname: Soler Fernández
mesh_terms: D014943:Global Health / Q000266:history; D049668:History, 15th Century; D049669:History, 16th Century; D049670:History, 17th Century; D049672:History, 19th Century; D049690:History, Ancient; D049691:History, Medieval; D006801:Humans; D010001:Osteitis Deformans / Q000175:diagnosis / Q000453:epidemiology / Q000266:history* / Q000473:pathology; D010164:Paleopathology
keywords: Epidemiology; Epidemiología; Historic; Histórico; Osteitis deformans; Osteítis deformante; Paleopathology; Paleopatología; Roman; Romano