title: Blood Component Utilization for Disseminated Intravascular Coagulation (DIC) Cases with Respect to Underlying Condition.
abstract: To understand transfusion requirement in DIC with respect to (wrt) underlying cause. Patients' details were analyzed using parameters like yearly requirement, hemoglobin (Hb) and blood components utilization wrt age, sex and cause of DIC. Total 1931 DIC cases from 167 hospitals received 21,153 blood units including whole blood, red cell concentrate fresh frozen plasma, random donor platelets, single donor platelets and cryoprecipitate from year 2001 to 2013. Significant risk of DIC was for females compared to males (p < 0.0001). Whole blood utilization was 25.5 % in 2001 which reduced to 1.2 % in 2013. Mean ± SD Hb concentration was 8.6 ± 3.0 in females and 9.8 ± 3.2 g/dL in males. The lowest mean Hb was 7 g/dL in female DIC cases having malignancy. Septicemia was the major cause of DIC followed by obstetric complications. The highest requirement was for trauma associated with septicemia, requiring 35 units/case. Combination of two or more underlying causes for DIC increased the blood component requirement.
authors.affiliation: Surat Raktadan Kendra & Research Centre (NABH Accredited Regional Blood Transfusion Centre), 1st Floor, Khatodara Health Centre, Besides Chosath Joganiyo Mata's Temple, Udhana Magdalla Road, Khatodara, Surat, 394 210 India.
authors.forename: Snehalata C
authors.initials: SC
authors.lastname: Gupte
authors.affiliation: Surat Raktadan Kendra & Research Centre (NABH Accredited Regional Blood Transfusion Centre), 1st Floor, Khatodara Health Centre, Besides Chosath Joganiyo Mata's Temple, Udhana Magdalla Road, Khatodara, Surat, 394 210 India.
authors.forename: Abhay G
authors.initials: AG
authors.lastname: Jhaveri
keywords: Blood components; Disseminated intravascular coagulation (DIC); Liver disorders; Obstetric complications; Septicemia; Trauma