title: Platelet rich plasma in ocular surface.
abstract: The use of platelet-rich preparations has experienced a significant increase in recent years due to its role in tissue-repair and regeneration. The aim of this study is to examine the available evidence regarding the application of plasma rich in growth factors, and its variations, on the ocular surface. A review is also presented on the effects of platelet-derived growth factors, the implications of the preparation methods, and the existing literature on the safety and efficacy of these therapies in ocular surface diseases. Despite the widespread use of platelet preparations there is no consensus on the most appropriate preparation method, and growth factors concentration vary with different systems. These preparations have been used in the treatment of ocular surface diseases, such as dry eye or persistent epithelial defects, among others, with good safety and efficacy profiles, but further studies are needed to compare to the currently available alternatives.
authors.affiliation: Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, España. Electronic address: ana.riestra@fio.as.
authors.forename: A C
authors.initials: AC
authors.lastname: Riestra
authors.affiliation: Hospital Universitario Los Arcos del Mar Menor, Pozo Aledo, Murcia, España.
authors.forename: J M
authors.initials: JM
authors.lastname: Alonso-Herreros
authors.affiliation: Instituto Universitario Fernández-Vega, Fundación de Investigación Oftalmológica, Universidad de Oviedo, Oviedo, España.
authors.forename: J
authors.initials: J
authors.lastname: Merayo-Lloves
mesh_terms: D005128:Eye Diseases / Q000628:therapy*; D006801:Humans; D053657:Platelet-Rich Plasma
keywords: Blood products; Cornea; Córnea; Derivados hemáticos; Ocular surface; Plasma rich in growth factors; Plasma rico en factores de crecimiento; Plasma rico en plaquetas; Platelet rich plasma; Superficie ocular