title: The Plot Thickens: Diet Microbe Interactions May Modulate Thrombosis Risk.
abstract: Thrombosis plays an important role in cardiovascular disease (CVD). Platelet activation is an essential step in the genesis and propagation of atherothrombotic complications. In a recent publication, Zhu and colleagues report that gut microbe-derived TMAO enhances platelet responsiveness and thrombosis, providing a novel mechanistic connection between microbes and CVD (Zhu et al., 2016).
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA.
authors.forename: Ana
authors.initials: A
authors.lastname: Martínez-Del Campo
authors.affiliation: Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
authors.forename: Kymberleigh A
authors.initials: KA
authors.lastname: Romano
authors.affiliation: Department of Bacteriology, University of Wisconsin-Madison, Madison, WI 53706, USA.
authors.forename: Federico E
authors.initials: FE
authors.lastname: Rey
authors.affiliation: Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address: balskus@chemistry.harvard.edu.
authors.forename: Emily P
authors.initials: EP
authors.lastname: Balskus
mesh_terms: D002318:Cardiovascular Diseases; D004032:Diet; D006801:Humans; D056265:Microbial Interactions; D013927:Thrombosis