title: Quality of Life and Mental State After Sight Restoration by Corneal Transplantation.
abstract: Quality of life has frequently been reported to improve after corneal transplantation. However, mental status before and after surgery has until now been less well investigated.
  
  
  
  The aim of this study was to investigate quality of life and mental status before and after corneal transplantation including postoperative immunosuppression and visual acuity.
  
  
  
  A total of 45 patients were assessed before, and 3 weeks and 4 months after transplantation using the following questionnaires: Visual Function Questionnaire, Beck Depression Inventory, and Hamilton Anxiety Rating Scale. Assessment included a visual acuity test using the logMAR chart, and recognition of the role of postoperative immunosuppression. Finally, patients were asked if they would be willing to have the surgery again.
  
  
  
  In the candidates for surgery, quality of life was reduced, and symptoms of depression and anxiety were present. Corneal transplantation improved their quality of life and reduced symptoms of depression and anxiety. Changes in quality of life and in mental state were associated with a change in visual acuity in the grafted eye. Higher doses of prednisone were associated with a worse quality of life and with more severe symptoms of depression and anxiety after transplantation. Further, 82.5% of patients would have the surgery again.
  
  
  
  Assessment for psychiatric symptoms should be considered in individuals facing corneal surgery.
authors.affiliation: Department of Psychiatry and Psychotherapy, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland. Electronic address: kdrzyzga@sum.edu.pl.
authors.forename: Karolina
authors.initials: K
authors.lastname: Drzyzga
authors.affiliation: Department of Psychiatry and Psychotherapy, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
authors.forename: Irena
authors.initials: I
authors.lastname: Krupka-Matuszczyk
authors.affiliation: Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Drzyzga
authors.affiliation: Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Mrukwa-Kominek
authors.affiliation: Department of Psychiatry and Psychotherapy, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Kucia
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001007:Anxiety / Q000523:psychology*; D001766:Blindness / Q000523:psychology / Q000601:surgery*; D003316:Corneal Diseases / Q000523:psychology / Q000601:surgery*; D016039:Corneal Transplantation; D003863:Depression / Q000523:psychology*; D005260:Female; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D011241:Prednisone / Q000627:therapeutic use; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D012307:Risk Factors; D011795:Surveys and Questionnaires; D014792:Visual Acuity; D055815:Young Adult
chemical_list: D007166:Immunosuppressive Agents; D011241:Prednisone
keywords: blindness; corneal surgery; corneal transplantation; quality of life; visual function