title: Microfluidics for effective concentration and sorting of waterborne protozoan pathogens.
abstract: We report on an inertial focussing based microfluidics technology for concentrating waterborne protozoa, achieving a 96% recovery rate of Cryptosporidium parvum and 86% for Giardia lamblia at a throughput (mL/min) capable of replacing centrifugation. The approach can easily be extended to other parasites and also bacteria.
authors.affiliation: Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot-Watt University, Riccarton, Scotland, Edinburgh EH14 4AS, United Kingdom. Electronic address: Melanie.jimenez@Glasgow.ac.uk.
authors.forename: M
authors.initials: M
authors.lastname: Jimenez
authors.affiliation: Institute of Biological Chemistry, Biophysics and Bioengineering, Heriot-Watt University, Riccarton, Scotland, Edinburgh EH14 4AS, United Kingdom.
authors.forename: H
authors.initials: H
authors.lastname: Bridle
mesh_terms: D001698:Biomedical Engineering / Q000379:methods; D002498:Centrifugation; D016785:Cryptosporidium parvum / Q000302:isolation & purification* / Q000472:pathogenicity; D004867:Equipment Design; D016829:Giardia lamblia / Q000302:isolation & purification* / Q000472:pathogenicity; D046210:Microfluidic Analytical Techniques / Q000379:methods*; D044085:Microfluidics; D014867:Water / Q000469:parasitology*
chemical_list: D014867:Water
keywords: Concentration; Cryptosporidium; Giardia; Microfluidics; Protozoa; Recovery rate; Sample processing; Waterborne disease