title: Outcomes of different protocols of pelvic floor physical therapy and anti-cholinergics in women with wet over-active bladder: A 4-year follow-up.
abstract: We investigated the 4-year outcomes of three protocols of pelvic floor physical therapy and anticholinergic drug in women with wet over-active bladder (OAB).
  
  
  
  One hundred and sixty-four women were randomly allocated to one of four interventions: drug therapy (DT), bladder training (BT), pelvic floor muscle training (PFMT), or combined pelvic floor rehabilitation (CPFR) that includes BT, PFMT, and behavioral advice. The active treatment in each group lasted 3 months. Of the 132 women who completed a 1-year follow-up, 120 women (90%) responded to our questionnaires and therefore were included in this study. Outcome measures were the number of voids per day, number of urgency urinary incontinence (UUI) episodes per week, completely dry rate and Incontinence Quality of Life questionnaire (I-QOL) at 4 years.
  
  
  
  After 4 years of follow-up, the outcome measures improved significantly and equally in all four groups. The median number of UUI episodes/week dropped by 3, 1, 2, and 2 in the DT, BT, PFMT, and CPFR groups, respectively (P = ns). The dry rates were 25%, 31%, 44%, 34% in the DT, BT, PFMT, and CPFR groups, respectively (P = ns). I-QOL scores improved significantly in all four groups.
  
  
  
  Women who suffer from wet-OAB may experience the same degree of long-term improvement following various pelvic floor physical therapy protocols as they would from drug therapy. Neurourol. Urodynam. 36:755-758, 2017. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Maccabi Healthcare Services, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv, Israel.
authors.forename: Joseph
authors.initials: J
authors.lastname: Azuri
authors.affiliation: Department of Physical Therapy, Maccabi Healthcare Services, Rishon Lezion, Israel.
authors.forename: Rachel
authors.initials: R
authors.lastname: Kafri
authors.affiliation: Sackler Faculty of Medicine, Department of Epidemiology and Preventive Medicine, School of Public Health, Tel-Aviv University, Tel Aviv, Israel.
authors.forename: Tomer
authors.initials: T
authors.lastname: Ziv-Baran
authors.affiliation: Department of Urology, Assaf Harofeh Medical Center, Zerifin, Affiliated to Sackler School of Medicine, Tel-Aviv University, Tel Aviv, Israel.
authors.forename: Kobi
authors.initials: K
authors.lastname: Stav
mesh_terms: D000368:Aged; D018680:Cholinergic Antagonists / Q000627:therapeutic use*; D003131:Combined Modality Therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D017773:Pelvic Floor / Q000503:physiopathology*; D026741:Physical Therapy Modalities; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D053201:Urinary Bladder, Overactive / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*; D014549:Urinary Incontinence / Q000188:drug therapy / Q000503:physiopathology / Q000628:therapy*
chemical_list: D018680:Cholinergic Antagonists
keywords: bladder training; overactive bladder; pelvic floor muscle training; pelvic floor rehabilitation; urgency urinary incontinence