title: State-of-the-Art Review of 3D Bioprinting for Cardiovascular Tissue Engineering.
abstract: 3D bioprinting is a group of rapidly growing techniques that allows building engineered tissue constructs with complex and hierarchical structures, mechanical and biological heterogeneity. It enables implementation of various bioinks through different printing mechanisms and precise deposition of cell and/or biomolecule laden biomaterials in predefined locations. This review briefly summarizes applicable bioink materials and various bioprinting techniques, and presents the recent advances in bioprinting of cardiovascular tissues, with focusing on vascularized constructs, myocardium and heart valve conduits. Current challenges and further perspectives are also discussed to help guide the bioink and bioprinter development, improve bioprinting strategies and direct future organ bioprinting and translational applications.
authors.affiliation: Division of Cardiology, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, 68198, USA. bin.duan@unmc.edu.|Mary & Dick Holland Regenerative Medicine Program, University of Nebraska Medical Center, Omaha, NE, 68198, USA. bin.duan@unmc.edu.
authors.forename: Bin
authors.initials: B
authors.lastname: Duan
mesh_terms: D000818:Animals; D001672:Biocompatible Materials / Q000737:chemistry*; D006350:Heart Valve Prosthesis; D006801:Humans; D009206:Myocardium; D066330:Printing, Three-Dimensional; D023822:Tissue Engineering / Q000295:instrumentation / Q000379:methods
chemical_list: D001672:Biocompatible Materials
keywords: Bioink; Heart valve; Hydrogel; Organ Bioprinting; Vascularization