title: [Optimization for vacuum belt drying process of Qibai Pingfei granule through response surface methodology].
abstract: Based on single factor tests,the optimum vacuum belt drying conditions of Qibai Pingfei granule were obtained through Box-Benhnken central combination design and RSM. In this study, drying time, drying temperature and extract density were chosen as independent variables, while transferring rate ginsenoside Rg₁, Re, Rb₁and astragaloside IV were taken as dependent variables. The optimum parameters are as follows: drying time of 112 min, drying temperature of 87 °C and extract density of 1.30 g · mL⁻¹. At the optimum condition, transferring rate ginsenoside Rg₁+ Re, Rb₁and astragaloside IV were 88.01%, 87.31%, 84. 34%. Above all, the optimum processing parameters of vacuum belt drying of Qibai Pingfei granule is reasonable and feasible, which can provide reliable basis for production.
authors.forename: Xue-feng
authors.initials: XF
authors.lastname: Li
authors.forename: Zhen-qiu
authors.initials: ZQ
authors.lastname: Xu
authors.forename: Ming
authors.initials: M
authors.lastname: Yan
authors.forename: Jing
authors.initials: J
authors.lastname: Shang
authors.forename: Yan-jun
authors.initials: YJ
authors.lastname: Zhang
authors.forename: Hui-juan
authors.initials: HJ
authors.lastname: Mi
authors.forename: Wei
authors.initials: W
authors.lastname: Xiao
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000295:instrumentation / Q000379:methods*; D003890:Desiccation / Q000295:instrumentation / Q000379:methods*; D004365:Drugs, Chinese Herbal / Q000737:chemistry*; D010946:Plants, Medicinal / Q000737:chemistry*; D011786:Quality Control; D013696:Temperature; D014618:Vacuum
chemical_list: D004365:Drugs, Chinese Herbal