title: Effect of condensed tannins supplementation through leaf meal mixture on voluntary feed intake, immune response and worm burden in Haemonchus contortus infected sheep.
abstract: The study was carried out to assess the effect of condensed tannins (CT) supplementation through leaf meal mixture (LMM) on feed intake, humoral [Immunoglobulin G (IgG)], cell mediated immune response (CMI) and faecal egg counts in Haemonchus contortus infected sheep. Eighteen sheep were randomly divided into three groups (negative control-NC, infected control-C and Infected treatment-T) of six animals in each group in a completely randomized block design for a period of 90 days. Twelve H. contortus infected adult sheep were allocated into two equal groups C and T, supplemented with 0 and 1.5 % of CT, respectively. Six non-infected sheep of similar age and body weight of NC group were included in this study to compare their immune response with H. contortus C and CT supplemented T groups. Intake of dry matter and organic matter (g day(-1) and % live weight) was statistically similar (P < 0.05) among the three groups. The anti-Haemonchus IgG and CMI response was higher in T group as compared to C group. The mean faecal egg counts was significantly (P < 0.001) higher in C group as compared to T group. It may be concluded that dietary supplementation of CT (1.5 %) through LMM improved humoral and CMI immune response and decreased worm load in H. contortus infected sheep.
authors.affiliation: Centre of Advanced Faculty Training in Animal Nutrition Division, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122 UP India ; Division of Animal Nutrition, Faculty of Veterinary Sciences & AH, SKUAST-J, R. S. Pura, Jammu, 181 102 India.
authors.forename: A K
authors.initials: AK
authors.lastname: Pathak
authors.affiliation: Centre of Advanced Faculty Training in Animal Nutrition Division, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122 UP India.
authors.forename: Narayan
authors.initials: N
authors.lastname: Dutta
authors.affiliation: Parasitology Division, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: P S
authors.initials: PS
authors.lastname: Banerjee
authors.affiliation: Immunology Division, Indian Veterinary Research Institute, Izatnagar, 243 122 UP India.
authors.forename: T K
authors.initials: TK
authors.lastname: Goswami
authors.affiliation: Centre of Advanced Faculty Training in Animal Nutrition Division, Indian Veterinary Research Institute, Izatnagar, Bareilly, 243 122 UP India ; Indian Council of Agricultural Research, Krishi Anusandhan Bhawan, New Delhi, 110 012 India.
authors.forename: K
authors.initials: K
authors.lastname: Sharma
keywords: Condensed tannins; Haemonchus contortus infection; Immune response; Leaf meal mixture; Sheep