title: Chest CT for suspected pulmonary complications of oncologic therapies: how I review and report.
abstract: In cancer patient during or following oncologic therapies with respiratory symptoms and pulmonary pathology at chest CT the differential diagnosis includes infection, therapy-induced disease and tumour progression.Although CT morphology may be typical or even pathognomonic in some conditions the diagnosis is usually made by a synopsis of imaging, clinical and laboratory features.Close communication with referring colleagues and a good knowledge of potential side effects of therapeutic concepts, their time course and CT morphology is crucial in the differential diagnosis.This review describes a personal approach to the radiological diagnosis of therapy-induced pulmonary abnormalities in cancer patients.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Marien Hospital, Academic Teaching Hospital, Rochusstr. 2, D- 40479, Düsseldorf, Germany. stefan.diederich@vkkd-kliniken.de.
authors.forename: Stefan
authors.initials: S
authors.lastname: Diederich
mesh_terms: D000970:Antineoplastic Agents / Q000633:toxicity; D003287:Contrast Media; D018549:Cryptogenic Organizing Pneumonia / Q000175:diagnosis; D003937:Diagnosis, Differential; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008168:Lung / Q000187:drug effects; D008171:Lung Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D008175:Lung Neoplasms / Q000175:diagnosis / Q000556:secondary; D008206:Lymphatic Diseases / Q000175:diagnosis; D009369:Neoplasms / Q000628:therapy*; D009503:Neutropenia / Q000175:diagnosis; D016066:Pleural Effusion, Malignant / Q000175:diagnosis; D045363:Pneumocystis carinii / Q000302:isolation & purification; D011014:Pneumonia / Q000175:diagnosis / Q000382:microbiology; D011020:Pneumonia, Pneumocystis / Q000175:diagnosis; D011654:Pulmonary Edema / Q000175:diagnosis; D011655:Pulmonary Embolism / Q000175:diagnosis; D017564:Radiation Pneumonitis / Q000175:diagnosis; D013902:Radiography, Thoracic / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D000970:Antineoplastic Agents; D003287:Contrast Media
keywords: Computed tomography; Cryptogenic organizing pneumonia; Drug toxicity; Image display; Image interpretation; Infection; Lung; Oedema; Radiation pneumonitis