title: Plastic Antibodies for Cosmetics: Molecularly Imprinted Polymers Scavenge Precursors of Malodors.
abstract: Molecularly imprinted polymers (MIPs) are synthetic antibody mimics capable of specific molecular recognition. Advantageously, they are more stable, easy to tailor for a given application and less expensive than antibodies. These plastic antibodies are raising increasing interest and one relatively unexplored domain in which they could outplay these advantages particularly well is cosmetics. Here, we present the use of a MIP as an active ingredient of a cosmetic product, for suppressing body odors. In a dermo-cosmetic formulation, the MIP captures selectively the precursors of malodorous compounds, amidst a multitude of other molecules present in human sweat. These results pave the way to the fabrication of a novel generation of MIPs with improved selectivities in highly complex aqueous environments, and should be applicable to biotechnological and biomedical areas as well.
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France.
authors.forename: Sofia
authors.initials: S
authors.lastname: Nestora
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France.
authors.forename: Franck
authors.initials: F
authors.lastname: Merlier
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France.
authors.forename: Selim
authors.initials: S
authors.lastname: Beyazit
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France.
authors.forename: Elise
authors.initials: E
authors.lastname: Prost
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France.
authors.forename: Luminita
authors.initials: L
authors.lastname: Duma
authors.affiliation: L'Oréal Research and Innovation, 1 avenue Eugène Schueller, 93600, Aulnay sous Bois, France.
authors.forename: Bérangère
authors.initials: B
authors.lastname: Baril
authors.affiliation: L'Oréal Research and Innovation, 1 avenue Eugène Schueller, 93600, Aulnay sous Bois, France.
authors.forename: Andrew
authors.initials: A
authors.lastname: Greaves
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France. karsten.haupt@utc.fr.
authors.forename: Karsten
authors.initials: K
authors.lastname: Haupt
authors.affiliation: Sorbonne Universités - Université de Technologie de Compiègne, CNRS Enzyme and Cell Engineering Laboratory, CS 60319, 60203, Compiègne Cedex, France. jeanne.tse-sum-bui@utc.fr.
authors.forename: Bernadette
authors.initials: B
authors.lastname: Tse Sum Bui
keywords: body odors; cosmetics; human sweat; molecularly imprinted polymer; stoichiometric monomer