title: [Tumor stem cells in breast cancer].
abstract: High mortality from breast cancer is associated with the high heterogeneity of tumor and the frequent recurrences of the pathological process, which are due to the presence of tumor stem cells. The review considers the biological properties of tumor stem cells, the molecular mechanisms of their regulation, interaction with the microenvironment, and their role in the heterogeneity of the morphological and clinical forms of breast cancer.
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation.
authors.forename: A A
authors.initials: AA
authors.lastname: Ivanov
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation.
authors.forename: O P
authors.initials: OP
authors.lastname: Popova
authors.affiliation: N.K. Koltsov Institute for Developmental Biology, Russian Academy of Sciences, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Kuznetsova
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation.
authors.forename: T I
authors.initials: TI
authors.lastname: Danilova
mesh_terms: D001943:Breast Neoplasms / Q000235:genetics* / Q000473:pathology; D005260:Female; D018740:Genetic Heterogeneity; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000235:genetics* / Q000473:pathology; D014411:Neoplastic Stem Cells / Q000473:pathology; D059016:Tumor Microenvironment / Q000235:genetics*