title: Lipid Nanoparticles and their Application in Nanomedicine.
abstract: In recent years many different nanotechnology platforms have been developed for both diagnostics and cancer therapy. Researchers have been attracted to use lipid-based nanoparticles with particle size approximately 100 nm as a new pharmaceutical delivery system or pharmaceutical formulation that can be assembled from different types of lipid or other chemical components in order to overcome biological barriers. This mini-review highlights the recently published studies in the development of lipid-based nanoparticles as appropriate vehicles in cancer diagnosis and therapy with focus on their chemical structure, formulation recipes, stability, drug encapsulation, and other factors related to their formulation.
authors.forename: Mehdi
authors.initials: M
authors.lastname: Rajabi
authors.affiliation: Pharmaceutical Research Institute, Albany College of Pharmacy and Health Sciences, 1 Discovery Drive, Suite 238, Rensselaer, New York 12144, USA. shaker.mousa@acphs.edu.
authors.forename: Shaker A
authors.initials: SA
authors.lastname: Mousa
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods*; D004355:Drug Stability; D006801:Humans; D008055:Lipids / Q000737:chemistry*; D050997:Nanomedicine / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology; D010316:Particle Size
chemical_list: D008055:Lipids