title: Validity Study of Vertebral Rotation Measurement Using 3-D Ultrasound in Adolescent Idiopathic Scoliosis.
abstract: This study aimed to assess the validity of 3-D ultrasound measurements on the vertebral rotation of adolescent idiopathic scoliosis (AIS) under clinical settings. Thirty curves (mean Cobb angle: 21.7° ± 15.9°) from 16 patients with AIS were recruited. 3-D ultrasound and magnetic resonance imaging scans were performed at the supine position. Each of the two raters measured the apical vertebral rotation using the center of laminae (COL) method in the 3-D ultrasound images and the Aaro-Dahlborn method in the magnetic resonance images. The intra- and inter-reliability of the COL method was demonstrated by the intra-class correlation coefficient (ICC) (both [2, K] >0.9, p < 0.05). The COL method showed no significant difference (p < 0.05) compared with the Aaro-Dahlborn method. Furthermore, the agreement between these two methods was demonstrated by the Bland-Altman method, and high correlation was found (r > 0.9, p < 0.05). These results validated the proposed 3-D ultrasound method in the measurements of vertebral rotation in the patients with AIS.
authors.affiliation: Interdisciplinary Division of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China; Center of Rehabilitation Medicine, West China Hospital, Sichuan University, Chengdu, China; Institute for Disaster Management and Reconstruction, Sichuan University-The Hong Kong Polytechnic University, Chengdu, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Interdisciplinary Division of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China.
authors.forename: Meng
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Canada.
authors.forename: Edmond H M
authors.initials: EH
authors.lastname: Lou
authors.affiliation: Department of Imaging & Interventional Radiology, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Winnie C W
authors.initials: WC
authors.lastname: Chu
authors.affiliation: Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Tsz-Ping
authors.initials: TP
authors.lastname: Lam
authors.affiliation: Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: Jack C Y
authors.initials: JC
authors.lastname: Cheng
authors.affiliation: Interdisciplinary Division of Biomedical Engineering, The Hong Kong Polytechnic University, Hong Kong, China. Electronic address: m.s.wong@polyu.edu.hk.
authors.forename: Man-Sang
authors.initials: MS
authors.lastname: Wong
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008279:Magnetic Resonance Imaging; D015203:Reproducibility of Results; D012399:Rotation; D012600:Scoliosis / Q000000981:diagnostic imaging*; D013131:Spine / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D014463:Ultrasonography / Q000379:methods*
keywords: 3-D ultrasound; Adolescent idiopathic scoliosis; Measurement; Validity; Vertebral rotation; reliability