title: Are Metformin Doses Used in Murine Cancer Models Clinically Relevant?
authors.affiliation: Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA. Electronic address: nav@northwestern.edu.
authors.forename: Navdeep S
authors.initials: NS
authors.lastname: Chandel
authors.affiliation: Goodman and Segal Cancer Centers, McGill University, 3755 Cote-Sainte-Catherine Road, Montreal, QC H3T 1E2, Canada.
authors.forename: Dania
authors.initials: D
authors.lastname: Avizonis
authors.affiliation: Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Colleen R
authors.initials: CR
authors.lastname: Reczek
authors.affiliation: Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
authors.forename: Samuel E
authors.initials: SE
authors.lastname: Weinberg
authors.affiliation: BPH, GDD, Global Early Development, DMPK, Bayer Pharma AG, Müllerstraße 178, 13353 Berlin, Germany.
authors.forename: Stephan
authors.initials: S
authors.lastname: Menz
authors.affiliation: BPH, GDD, Global Early Development, DMPK, Bayer Pharma AG, Müllerstraße 178, 13353 Berlin, Germany.
authors.forename: Roland
authors.initials: R
authors.lastname: Neuhaus
authors.affiliation: BPH, GDD, Global Therapeutic Research Group Oncology II, Bayer Pharma AG, Müllerstraße 178, 13353 Berlin, Germany.
authors.forename: Sven
authors.initials: S
authors.lastname: Christian
authors.affiliation: BPH, GDD, Global Therapeutic Research Group Oncology II, Bayer Pharma AG, Müllerstraße 178, 13353 Berlin, Germany.
authors.forename: Andrea
authors.initials: A
authors.lastname: Haegebarth
authors.affiliation: BPH, GDD, Global Therapeutic Research Group Oncology II, Bayer Pharma AG, Müllerstraße 178, 13353 Berlin, Germany.
authors.forename: Carolyn
authors.initials: C
authors.lastname: Algire
authors.affiliation: Goodman and Segal Cancer Centers, McGill University, 3755 Cote-Sainte-Catherine Road, Montreal, QC H3T 1E2, Canada. Electronic address: michael.pollak@mcgill.ca.
authors.forename: Michael
authors.initials: M
authors.lastname: Pollak
mesh_terms: D000818:Animals; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D004195:Disease Models, Animal; D004305:Dose-Response Relationship, Drug; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D008687:Metformin / Q000008:administration & dosage / Q000494:pharmacology / Q000627:therapeutic use*; D051379:Mice; D008810:Mice, Inbred C57BL; D009369:Neoplasms / Q000188:drug therapy* / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D007004:Hypoglycemic Agents; D008687:Metformin