title: Are Weight Status and Cognition Associated? An Examination of Cognitive Development in Children and Adolescents with Anorexia Nervosa 1 Year after First Hospitalisation.
abstract: The aim of this study was to characterise the association between the cognitive profile and weight restoration in children and adolescents with anorexia nervosa.
  
  
  
  The study was a longitudinal, matched case-control, multicentre study. An assessment of cognitive functions was conducted by using the Wechsler Intelligence Scale for Children-III/the Wechsler Adult Intelligence Scale-III, the Test of Memory and Learning-second edition, Trail Making Tests A and B, the Rey-Osterrieth Complex Figure Test and the Cambridge Neuropsychological Test Automated Battery.
  
  
  
  One hundred twenty individuals, 60 patients with anorexia nervosa with mean age of 14.65 (SD 1.820) years and 60 healthy controls with mean age of 14.76 (SD 1.704) years, participated. No association was found between weight recovery and cognitive functions. However, a significant increase in motor speed was found in Trail Making Test A (p = 0.004), Reaction Time (RTI) five-choice movement time (p = 0.002) and RTI simple movement time (p = 0.011), resulting in a normalisation corresponding to that found in healthy controls. Furthermore, a significantly lower score in the perceptual organization index (p = 0.029) was found at follow-up.
  
  
  
  Weight recovery appears not to be associated with cognition. Copyright © 2016 The Authors European Eating Disorders Review published by Eating Disorders Association and John Wiley & Sons Ltd.
authors.affiliation: Unit for Psychiatric Research, Aalborg University Hospital, Aalborg, Denmark.|Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.
authors.forename: Gry
authors.initials: G
authors.lastname: Kjaersdam Telléus
authors.affiliation: Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) and Center for Neuropsychiatric Schizophrenia Research (CNSR), Psychiatric Center Glostrup, Glostrup, Denmark.
authors.forename: Birgitte
authors.initials: B
authors.lastname: Fagerlund
authors.affiliation: Lundbeck Foundation Center for Clinical Intervention and Neuropsychiatric Schizophrenia Research (CINS) and Center for Neuropsychiatric Schizophrenia Research (CNSR), Psychiatric Center Glostrup, Glostrup, Denmark.|Child and Adolescent Mental Health Center, Mental Health Services, Copenhagen, Denmark.
authors.forename: Jens Richardt
authors.initials: JR
authors.lastname: Jepsen
authors.affiliation: Child and Adolescent Mental Health Center, Mental Health Services, Copenhagen, Denmark.
authors.forename: Mette
authors.initials: M
authors.lastname: Bentz
authors.affiliation: Medical Specialist Clinic in Child and Adolescent Psychiatry in a Private Setting, Copenhagen, Denmark.
authors.forename: Eva
authors.initials: E
authors.lastname: Christiansen
authors.affiliation: Unit for Psychiatric Research, Aalborg University Hospital, Aalborg, Denmark.
authors.forename: Jan Brink
authors.initials: JB
authors.lastname: Valentin
authors.affiliation: Department of Clinical Medicine, Faculty of Medicine, Aalborg University, Aalborg, Denmark.|Regional Centre of Child and Adolescent Psychiatry, Risskov.|Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Per Hove
authors.initials: PH
authors.lastname: Thomsen
mesh_terms: D000293:Adolescent; D000328:Adult; D000856:Anorexia Nervosa / Q000175:diagnosis / Q000523:psychology*; D001835:Body Weight; D002648:Child; D003071:Cognition; D003072:Cognition Disorders / Q000175:diagnosis* / Q000523:psychology; D005260:Female; D006760:Hospitalization; D006801:Humans; D007360:Intelligence; D007361:Intelligence Tests; D008297:Male; D008568:Memory; D009483:Neuropsychological Tests / Q000706:statistics & numerical data*; D014145:Trail Making Test; D014888:Wechsler Scales
keywords: adolescents; anorexia nervosa; children; cognitive functions; follow-up; weight recovery; weight status