title: Outcomes of Same Day Pacemaker Implantation after TAVI.
abstract: BACKGROUND
  Transcatheter aortic valve implantation (TAVI) is often associated with conduction disturbances, followed by permanent pacemaker (PPM) implantation. Because of the potential reversibility of these conduction disorders, controversy exists regarding the right timing of PPM implantation. TAVI is routinely performed under dual-antiplatelet and antithrombotic therapy, which poses an additional hemorrhagic risk on a same-day procedure. The aim of the present study was to evaluate the safety and effectiveness of same-day PPM implantation in patients undergoing TAVI.
  
  
  METHODS
  Consecutive patients undergoing TAVI with Medtronic Corevalve bioprosthesis (Medtronic Inc., Minneapolis, MN, USA) in a tertiary center were divided into two study groups. Group A included patients undergoing PPM implantation the same day with TAVI, and Group B patients were implanted with a PPM later after TAVI and before hospital discharge. The two study groups were compared for all complications associated with PPM implantation.
  
  
  RESULTS
  In total, 168 patients were included in the study. PPM was implanted in 65 patients (38.7%). In 23 patients, a PPM was implanted the same day with TAVI (Group A) and in 42 patients PPM implantation was postponed at least 1 day (Group B). Cephalic vein was the access used for the leads in the majority of cases. There was only one case of pneumothorax in Group B. There were no differences in the incidence of pocket hematomas between the study groups.
  
  
  CONCLUSIONS
  Same-day PPM implantation after TAVI is safe and feasible. Strategies reducing pocket hematomas are essential in such patients of high hemorrhagic risk.
authors.affiliation: Cardiac Department, Hippokration Hospital, Athens, Greece.
authors.forename: Skevos
authors.initials: S
authors.lastname: Sideris
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: Georgios
authors.initials: G
authors.lastname: Benetos
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Toutouzas
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Drakopoulou
authors.affiliation: Cardiac Department, Hippokration Hospital, Athens, Greece.
authors.forename: Elias
authors.initials: E
authors.lastname: Sotiropoulos
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Gatzoulis
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Latsios
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: Andreas
authors.initials: A
authors.lastname: Synetos
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Trantalis
authors.affiliation: First Department of Cardiology, Hippokration Hospital, Athens School of Medicine, Athens, Greece.
authors.forename: Dimitris
authors.initials: D
authors.lastname: Tousoulis
authors.affiliation: Cardiac Department, Hippokration Hospital, Athens, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kallikazaros
mesh_terms: D000368:Aged; D001024:Aortic Valve Stenosis / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D003131:Combined Modality Therapy / Q000379:methods; D005260:Female; D006115:Greece / Q000453:epidemiology; D006801:Humans; D008297:Male; D010138:Pacemaker, Artificial / Q000706:statistics & numerical data*; D015995:Prevalence; D019736:Prostheses and Implants / Q000706:statistics & numerical data*; D012307:Risk Factors; D013997:Time Factors; D065467:Transcatheter Aortic Valve Replacement / Q000706:statistics & numerical data*; D016896:Treatment Outcome
keywords: TAVI; bleeding; pacemaker implantation; timing