title: Tenosynovial Giant Cell Tumor in the Dermis of the External Auditory Meatus.
abstract: A 26-year-old African American woman with a history of a recurring "oozing papule" in the right ear presented to the emergency department in July 2010 with a 2-month history of an enlarging, painful growth in the right ear canal. Physical examination revealed a 1-cm round cystic lesion along the right, anterior external auditory canal wall, just medial to the tragus. Initial diagnosis was an infected cyst of the external ear canal. The patient was instructed to follow-up with an ear, nose, and throat (ENT) office. Two months following the emergency department visit, inspection by ENT revealed a 3- to 4-mm round, firm subcutaneous nodule that did not extend into the ear canal or cartilage. According to the patient, this lesion had recurred with several infections. The lesion was biopsied in the outpatient setting and demonstrated ulceration with marked acute and chronic inflammation in addition to granulation tissue. Two months later, the lesion was surgically excised. The final diagnosis of giant cell tumor, tenosynovial type with lesion-free margins, and no involvement of the cartilage was made (Figures 1-3). No further treatment was recommended. Gross examination of the excised lesion revealed tan to white soft tissue measuring 1.0×0.7×0.3 cm. Results from factor XIII A immunostain was negative, confirming that the lesion did not represent an unusual variant of fibrous histiocytoma (Figure 4). To date, recurrence of this lesion has not been appreciated.
authors.affiliation: Department of Dermatology, Rutgers University-New Jersey Medical School, Newark, NJ.|Department of Pathology, Rutgers University-New Jersey Medical School, Newark, NJ.
authors.forename: Amin
authors.initials: A
authors.lastname: Maghari
authors.affiliation: Rowan University, School of Osteopathic Medicine, Stratford, NJ.
authors.forename: Theresa A
authors.initials: TA
authors.lastname: Zaleski
authors.affiliation: Department of Dermatology, Rutgers University-New Jersey Medical School, Newark, NJ.|Department of Pathology, Rutgers University-New Jersey Medical School, Newark, NJ.
authors.forename: Tiffany
authors.initials: T
authors.lastname: Jow
authors.affiliation: Department of Dermatology, Rutgers University-New Jersey Medical School, Newark, NJ.|Department of Pathology, Rutgers University-New Jersey Medical School, Newark, NJ; lamberwc@umdnj.edu.
authors.forename: W Clark
authors.initials: WC
authors.lastname: Lambert
mesh_terms: D000328:Adult; D004424:Ear Canal; D004428:Ear Neoplasms / Q000473:pathology*; D005260:Female; D000070779:Giant Cell Tumor of Tendon Sheath / Q000473:pathology*; D006801:Humans; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D012878:Skin Neoplasms / Q000473:pathology*