title: Physiological Activities of Thiacremonone Produced in High Temperature and High Pressure Treated Garlic.
abstract: To examine the possibility of using thiacremonone isolated from high-temperature-high-pressure treated garlic, this study investigated the physiological activities properties. The IC50 values of hydroxyl, superoxide, hydrogen peroxide, and nitric oxide radical scavenging activities of thiacremonone were 92.50, 65.05, 12.60, and 81.53 μg/mL, respectively. On the other hand, the activities of vitamin C were 104.93, 99.43, 42.42, and 122.64 μg/mL, and the activities of butylated hydroxyanisole were 37.22, 68.45, 22.47, and 40.54 μg/mL, respectively. The IC50 value of ACE inhibition activities of thiacremonone and captoprill were 0.265 and 0.036 μg/mL, respectively. The IC50 value of xanthine oxidase inhibition activities of thiacremonone and allopurinol were 39.430 and 9.346 μg/mL, respectively. The IC50 value of tyrosinase inhibition activities of thiacremonone and kojic acid were 101.931 and 65.648 μg/mL, respectively.
authors.affiliation: National Institute of Crop Science, Rural Development Administration, Gyeonggi 16616, Korea.
authors.forename: Koan Sik
authors.initials: KS
authors.lastname: Woo
authors.affiliation: National Academy of Agricultural Science, Rural Development Administration, Jeonbuk 54875, Korea.
authors.forename: In Guk
authors.initials: IG
authors.lastname: Hwang
authors.affiliation: National Institute of Crop Science, Rural Development Administration, Gyeonggi 16616, Korea.
authors.forename: Hyun Young
authors.initials: HY
authors.lastname: Kim
authors.affiliation: Department of Food Science and Technology, Chungbuk National University, Chungbuk 28644, Korea.
authors.forename: Sang Hoon
authors.initials: SH
authors.lastname: Lee
authors.affiliation: Department of Food Science and Technology, Chungbuk National University, Chungbuk 28644, Korea.
authors.forename: Heon Sang
authors.initials: HS
authors.lastname: Jeong
keywords: 2,4-dihydroxy-2,5-dimethyl-thiophene-3-one; garlic (Allium sativum L.); radical scavenging activity; thiacremonone