title: The Distribution of 18 Enterotoxin and Enterotoxin-Like Genes in Staphylococcus aureus Strains from Different Sources in East China.
abstract: The distribution of 18 staphylococcal enterotoxin (SE) or SE-like (SEl) genes in Staphylococcus aureus strains from different sources in east China was investigated. Among all 496 S. aureus strains, 291 strains carried one or more SE genes. The more frequently occurred genes were sea, seb, seg, selk, sell, selm, selo, and seq; the less frequent occurred genes were sec, selj, and ser. The classic SE genes and the enterotoxin gene cluster (egc) (seg, sei, selm, seln, selo, and/or selu) accounted for 25.67% and 61.68% of all detected genes, respectively. There were three gene clusters (egc, sea-sek-seq, and sed-sej-ser), of which the egc cluster was the important one that could generate novel complexes, and the sea-sek-seq cluster was a close relative to the hospital-acquired methicillin-resistant S. aureus. The SE gene distributions were different among strains of different sources and formed diverse toxin gene profiles. The human- and foodborne-origin strains harbored classic and novel SE and SEl genes, whereas animal-origin strains harbored egc and other novel SE and SEl genes mainly. The foodborne- and human-origin strains were the main dangerous factors of classic staphylococcal foodborne poisoning, whereas the strains (especially from animals) that carried egc and other novel genes mainly should be new potential dangerous factors for food safety.
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Jinghua
authors.initials: J
authors.lastname: Cheng
authors.affiliation: 2 Yangzhou Center for Disease Control and Prevention , Yangzhou, China .
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Yongzhong
authors.initials: Y
authors.lastname: Cao
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Wenguang
authors.initials: W
authors.lastname: Yan
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Xiaosai
authors.initials: X
authors.lastname: Niu
authors.affiliation: 2 Yangzhou Center for Disease Control and Prevention , Yangzhou, China .
authors.forename: Liping
authors.initials: L
authors.lastname: Zhou
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Jianhao
authors.initials: J
authors.lastname: Chen
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Ying
authors.initials: Y
authors.lastname: Sun
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Chenxi
authors.initials: C
authors.lastname: Li
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Zhang
authors.affiliation: 1 Jiangsu Co-Innovation Center for Prevention of Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University , Yangzhou, China .
authors.forename: Yantao
authors.initials: Y
authors.lastname: Wu
mesh_terms: D000818:Animals; D000829:Animals, Domestic / Q000382:microbiology; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002681:China; D004768:Enterotoxins / Q000235:genetics* / Q000378:metabolism; D005513:Food Inspection; D005516:Food Microbiology; D005798:Genes, Bacterial; D006762:Hospitals, Animal; D006801:Humans; D008892:Milk / Q000382:microbiology; D058889:Molecular Typing / Q000662:veterinary; D005810:Multigene Family; D013202:Staphylococcal Food Poisoning / Q000382:microbiology / Q000662:veterinary; D013203:Staphylococcal Infections / Q000382:microbiology / Q000662:veterinary; D013211:Staphylococcus aureus / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification / Q000378:metabolism; D062606:Tertiary Care Centers; D037521:Virulence Factors / Q000235:genetics* / Q000378:metabolism
chemical_list: D001426:Bacterial Proteins; D004768:Enterotoxins; D037521:Virulence Factors