title: The incidence of post-operative adhesion following transection of uterine septum: a cohort study comparing three different adjuvant therapies.
abstract: OBJECTIVE
  To investigate the clinical efficacy of postoperative estrogen therapy, intrauterine device (IUD) and intrauterine balloon in preventing intrauterine adhesions after transcervical resection of septum (TCRS).
  
  
  METHODS
  238 patients who underwent TCRS in our hospital from March 2012 to December 2013 were allocated into one of four groups. In Group 1 (50 patients), women received postoperative estrogen therapy. In Group 2 (59 patients), an intrauterine contraceptive device (IUD) was placed into the uterine cavity at the end of the operation. In Group 3 (75 patients), a Foley catheter with the balloon inflated with 4ml of normal saline solution was placed into the uterine cavity at the end of the operation for five days. In Group 4 (54 patients), women did not receive any of the above treatment (comparison group). All subjects underwent two further hysteroscopy, one and three months after the initial surgery.
  
  
  RESULTS
  The intrauterine adhesion rates among the four groups at one month were 22.0%, 28.81, 26.7% and 24.1% (p>0.05); and at the third month were 0%, 1.7%, 1.3% and 3.4%, respectively (p>0.05).
  
  
  CONCLUSIONS
  The use of postoperative estrogen therapy, IUD or intrauterine balloon did not appear to have any benefit in reducing the incidence of postoperative intrauterine adhesion formation.
authors.affiliation: Department of Hysteroscopic Center, Fuxing Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Yu
authors.affiliation: Department of Hysteroscopic Center, Fuxing Hospital, Capital Medical University, Beijing 100038, China. Electronic address: rain_1022@163.com.
authors.forename: Liu
authors.initials: L
authors.lastname: Yuhan
authors.affiliation: Department of Hysteroscopic Center, Fuxing Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: Song
authors.initials: S
authors.lastname: Dongmei
authors.affiliation: Department of Hysteroscopic Center, Fuxing Hospital, Capital Medical University, Beijing 100038, China.
authors.forename: Xia
authors.initials: X
authors.lastname: Enlan
authors.affiliation: Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, China.
authors.forename: Li
authors.initials: L
authors.lastname: Tinchiu
mesh_terms: D000328:Adult; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D004967:Estrogens / Q000627:therapeutic use*; D005260:Female; D013509:Gynecologic Surgical Procedures / Q000009:adverse effects*; D006801:Humans; D007434:Intrauterine Devices; D000267:Tissue Adhesions / Q000453:epidemiology / Q000209:etiology / Q000517:prevention & control*; D014599:Uterus / Q000002:abnormalities* / Q000601:surgery
chemical_list: D004967:Estrogens
keywords: Foley balloon; Intrauterine adhesions; Uterine septum