title: Two Cases of Hypophosphatemia with Increased Renal Phosphate Excretion in Legionella Pneumonia.
abstract: We encountered 2 cases of hypophosphatemia due to Legionella pneumonia. Both cases showed increased urinary phosphate excretion and renal tubular dysfunction, which ameliorated with recovery from Legionella pneumonia. Serum fibroblast growth factor-23 level was suppressed, whereas serum 1,25(OH)2 vitamin D and parathyroid hormone levels were normal. Delayed elevation of serum 1,25(OH)2 vitamin D levels was observed with improvement in renal tubular function. These findings suggested hypophosphatemia might be mediated by renal tubular dysfunction.
authors.affiliation: Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, Kobe, Japan; Division of Nephrology, Akashi Medical Center, Akashi, Japan.
authors.forename: Shuhei
authors.initials: S
authors.lastname: Watanabe
authors.affiliation: Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, Kobe, Japan; Division of Nephrology, Akashi Medical Center, Akashi, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Kono
authors.affiliation: Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Fujii
authors.affiliation: Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Nakai
authors.affiliation: Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Goto
authors.affiliation: Division of Nephrology and Kidney Center, Kobe University Graduate School of Medicine, Kobe, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Nishi
keywords: 1,25(OH)2 vitamin D; Fibroblast growth factor-23; Hypophosphatemia; Legionella pneumonia; Renal tubular dysfunction