title: Lensless two-photon imaging through a multicore fiber with coherence-gated digital phase conjugation.
abstract: We performed near-diffraction limited two-photon fluorescence (TPF) imaging through a lensless, multicore-fiber (MCF) endoscope utilizing digital phase conjugation. The phase conjugation technique is compatible with commercially available MCFs with high core density. We demonstrate focusing of ultrashort pulses through an MCF and show that the method allows for resolution that is not limited by the MCF core spacing. We constructed TPF images of fluorescent beads and cells by digital scanning of the phase-conjugated focus on the target object and collection of the emitted fluorescence through the MCF.
authors.affiliation: École Polytechnique Fédérale de Lausanne, Laboratory of Optics, Station 17, Lausanne 1015, Switzerland.
authors.forename: Donald B
authors.initials: DB
authors.lastname: Conkey
authors.affiliation: École Polytechnique Fédérale de Lausanne, Laboratory of Optics, Station 17, Lausanne 1015, Switzerland.
authors.forename: Nicolino
authors.initials: N
authors.lastname: Stasio
authors.affiliation: École Polytechnique Fédérale de Lausanne, Laboratory of Applied Photonics Devices, Station 17, Lausanne 1015, Switzerland.
authors.forename: Edgar E
authors.initials: EE
authors.lastname: Morales-Delgado
authors.affiliation: École Polytechnique Fédérale de Lausanne, Laboratory of Optics, Station 17, Lausanne 1015, Switzerland.
authors.forename: Marilisa
authors.initials: M
authors.lastname: Romito
authors.affiliation: École Polytechnique Fédérale de Lausanne, Laboratory of Applied Photonics Devices, Station 17, Lausanne 1015, Switzerland.
authors.forename: Christophe
authors.initials: C
authors.lastname: Moser
authors.affiliation: École Polytechnique Fédérale de Lausanne, Laboratory of Optics, Station 17, Lausanne 1015, Switzerland.
authors.forename: Demetri
authors.initials: D
authors.lastname: Psaltis
mesh_terms: D019723:Endoscopes; D005336:Fiber Optic Technology / Q000295:instrumentation; D005456:Fluorescent Dyes; D045325:HCT116 Cells; D006696:Holography / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D061848:Optical Imaging / Q000295:instrumentation* / Q000379:methods*
chemical_list: D005456:Fluorescent Dyes