title: Antibiotic resistance: challenges and successes in respiratory infection.
abstract: European Respiratory Society Congress, Amsterdam, 26-30 September 2015, and CHEST 2015, Montréal, Canada, 24-28 October 2015 With approximately 50,000 deaths in the US and EU attributed to antibacterial resistance each year, together with several million days of hospital care [1], the need to address resistance mechanisms and find new targets for novel antibiotics has never been greater. At the annual congresses of the European Respiratory Society and the American College of Chest Physicians, presenters reported advances in understanding of the mechanisms of antibiotic resistance and how these may be overcome. The latest clinical trial data on antibiotic treatment for hospital- and community-acquired pneumonia, including the potential for novel nebulized forms of therapy, were also discussed.
authors.affiliation: University at Buffalo, New York, VA WNY Healthcare System, 3495 Bailey Avenue, Buffalo, NY 14215, USA.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Sethi
authors.affiliation: Medical writer, London, UK.
authors.forename: Jenny
authors.initials: J
authors.lastname: Bryan
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology* / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D017714:Community-Acquired Infections / Q000188:drug therapy / Q000382:microbiology; D003428:Cross Infection / Q000188:drug therapy / Q000382:microbiology; D024881:Drug Resistance, Bacterial; D004358:Drug Therapy / Q000379:methods; D014943:Global Health; D006801:Humans; D018410:Pneumonia, Bacterial / Q000188:drug therapy* / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents
keywords: antibiotics; antimicrobial resistance; respiratory infections