title: Successful treatment of ulcerated hemangiomas with a dual-wavelength 595- and 1064-nm laser system.
abstract: BACKGROUND
  Pulsed dye laser (PDL) treatment has been shown to be effective for the management of ulcerated areas of hemangiomas. However, targeting deeper dermal lesions requires a laser system that penetrates more deeply than a PDL. Thus, we applied a dual-wavelength 595- and 1064-nm laser system to the treatment of ulcerated hemangiomas.
  
  
  METHODS
  Twenty-two infants with ulcerated hemangiomas (mean are, 3.8 cm2) were reviewed. Ulcers were treated by debridement and the surface received 595-nm PDL treatment at 4-5 J/cm2with a pulse width of 0.5 ms. Then, the remaining hemangioma excluding the ulcerated portion was treated with dual-wavelength laser. Laser treatment was repeated at two-week intervals until cutaneous healing was observed.
  
  
  RESULTS
  Ulcerative lesions in 20 of the 22 patients (90.9%) healed entirely within 2 weeks following the first laser treatment. Two patients also required oral steroids, and one patient underwent two laser treatments. The follow-up period ranged from 6 to 24 months, and no evidence of recurrent ulceration or hemangioma regrowth was observed.
  
  
  CONCLUSIONS
  Our findings confirm that PDL treatment leads to a rapid decrease in pain and initiation of the healing process and indicate that dual-wavelength laser treatment offers rapid healing with few adverse effects.
authors.affiliation: a Department of Dermatology , the First Affiliated Hospital of Jinan University , Guangzhou , People's Republic of China.|b Department of Dermatology , Shanxi Children Hospital , Taiyuan , People's Republic of China.
authors.forename: Yuanjun
authors.initials: Y
authors.lastname: Li
authors.affiliation: a Department of Dermatology , the First Affiliated Hospital of Jinan University , Guangzhou , People's Republic of China.
authors.forename: Yunfeng
authors.initials: Y
authors.lastname: Hu
authors.affiliation: c Department of Dermatology , Guangzhou Women and Children's Medical Center , Guangzhou , People's Republic of China.
authors.forename: Haipian
authors.initials: H
authors.lastname: Li
authors.affiliation: a Department of Dermatology , the First Affiliated Hospital of Jinan University , Guangzhou , People's Republic of China.
authors.forename: Liehua
authors.initials: L
authors.lastname: Deng
mesh_terms: D003646:Debridement; D005260:Female; D006391:Hemangioma / Q000601:surgery*; D006801:Humans; D007223:Infant; D054025:Lasers, Dye / Q000627:therapeutic use*; D008297:Male; D016896:Treatment Outcome; D014456:Ulcer / Q000601:surgery; D014945:Wound Healing
keywords: Dual-wavelength laser system; infant; ulcerated hemangioma