title: Saprochaete clavata invasive infection in a patient with severe aplastic anemia: Efficacy of voriconazole and liposomal amphotericin B with adjuvant granulocyte transfusions before neutrophil recovery following allogeneic bone marrow transplantation.
abstract: We report a case of a 27-year old man with severe aplastic anemia who developed a Saprochaete clavata (Geotrichum clavatum) disseminated invasive infection shortly prior a scheduled allogeneic bone marrow transplantation. Treatment with a combination of voriconazole, liposomal amphotericin B and adjuvant granulocyte transfusions was successful before neutrophil recovery.
authors.affiliation: Service d'Hématologie et de Thérapie Cellulaire, CHU Haut-Lévêque, Bordeaux, France.
authors.forename: Simon
authors.initials: S
authors.lastname: Favre
authors.affiliation: Laboratoire de Parasitologie Mycologie, CHU Pellegrin, Bordeaux, France.
authors.forename: Amandine
authors.initials: A
authors.lastname: Rougeron
authors.affiliation: Etablissement Français du Sang, Bordeaux, France.
authors.forename: Laure
authors.initials: L
authors.lastname: Levoir
authors.affiliation: Service d'Hématologie et de Thérapie Cellulaire, CHU Haut-Lévêque, Bordeaux, France.
authors.forename: Baptiste
authors.initials: B
authors.lastname: Pérard
authors.affiliation: Service d'Hématologie et de Thérapie Cellulaire, CHU Haut-Lévêque, Bordeaux, France; Université Bordeaux Segalen, Bordeaux, France.
authors.forename: Noël
authors.initials: N
authors.lastname: Milpied
authors.affiliation: Laboratoire de Parasitologie Mycologie, CHU Pellegrin, Bordeaux, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Accoceberry
authors.affiliation: Laboratoire de Parasitologie Mycologie, CHU Pellegrin, Bordeaux, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Gabriel
authors.affiliation: Service d'Hématologie et de Thérapie Cellulaire, CHU Haut-Lévêque, Bordeaux, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Vigouroux
keywords: Aplastic anemia; Hematological disease; Invasive infection; Saprochaete clavata