title: [A Case of Chordoma of the Sacrum Treated with Pazopanib].
abstract: A-70-year-old man with chordoma of the sacrum was treated with pazopanib (initially 400 mg/day, upto 800 mg/day). After 2 months of treatment, a significant tumor reduction was achieved and the patient was able to sit down easily. Therefore, the pazopanib therapy was continued. He had 14 months of progression-free survival.
authors.affiliation: Dept. of Medical Oncology, Japanese Red Cross Society Suwa Hospital.
authors.forename: Akihiro
authors.initials: A
authors.lastname: Shinji
authors.forename: Satomi
authors.initials: S
authors.lastname: Okada
authors.forename: Toshitsugu
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D000368:Aged; D020533:Angiogenesis Inhibitors / Q000627:therapeutic use*; D001706:Biopsy; D002817:Chordoma / Q000188:drug therapy*; D006801:Humans; D007191:Indazoles; D008297:Male; D011743:Pyrimidines / Q000627:therapeutic use*; D011788:Quality of Life; D012447:Sacrum / Q000473:pathology*; D013125:Spinal Neoplasms / Q000188:drug therapy*; D013449:Sulfonamides / Q000627:therapeutic use*
chemical_list: D020533:Angiogenesis Inhibitors; D007191:Indazoles; D011743:Pyrimidines; D013449:Sulfonamides; C516667:pazopanib