title: Pregnancy in women with complete transposition of the great arteries following the atrial switch procedure. A study from three of the largest Adult Congenital Heart Disease centers in Poland.
abstract: OBJECTIVE
  We sought to identify maternal/neonatal and cardiovascular complications in pregnant women with complete transposition of great arteries (D-TGA) following atrial switch.
  
  
  METHODS
  Clinical records of all women with D-TGA after the Mustard/Senning (M/S) operation who were followed at the three largest Adult Congenital Heart Disease (ACHD) centers in Poland were reviewed.
  
  
  RESULTS
  Fifteen of the fifty-nine women followed had a total of 24 pregnancies, including two spontaneous miscarriages. Twenty-two pregnancies (92%) resulted in a live birth, 91% were by cesarean section. During 5 (23%) of the 22 completed pregnancies obstetric complications were observed (one gestational diabetes, one hypertension in pregnancy, one placenta increta and two preterm labors). The mean pregnancy duration was 37.2 weeks (range: 26-41 weeks).We observed one neonatal death due to extreme prematurity. Six (25%) children had a birth weight of ≤2500 g. None of women had severe cardiac complications during pregnancy nor in the postpartum period.
  
  
  CONCLUSIONS
  In our study, we demonstrated a large number of obstetric complications and low birth weight in the presence of a systemic right ventricle. However, from a cardiologist's point of view pregnancy after the M/S operation was well-tolerated and relatively safe.
authors.affiliation: a Department of Congenital Cardiac Defects , Institute of Cardiology , Warsaw , Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Lipczyńska
authors.affiliation: b Department of Acquired Cardiac Defects , Institute of Cardiology , Warsaw , Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Szymański
authors.affiliation: c First Department of Cardiology, University of Medical Sciences , Poznań , Poland.
authors.forename: Olga
authors.initials: O
authors.lastname: Trojnarska
authors.affiliation: d Institute of Cardiology, Jagiellonian University Medical College and John Paul II Hospital , Kraków , Poland , and.
authors.forename: Lidia
authors.initials: L
authors.lastname: Tomkiewicz-Pająk
authors.affiliation: e First Department of Obstetrics and Gynecology, Medical University of Warsaw , Warsaw , Poland.
authors.forename: Bronisława
authors.initials: B
authors.lastname: Pietrzak
authors.affiliation: a Department of Congenital Cardiac Defects , Institute of Cardiology , Warsaw , Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Klisiewicz
authors.affiliation: a Department of Congenital Cardiac Defects , Institute of Cardiology , Warsaw , Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Kumor
authors.affiliation: d Institute of Cardiology, Jagiellonian University Medical College and John Paul II Hospital , Kraków , Poland , and.
authors.forename: Piotr
authors.initials: P
authors.lastname: Podolec
authors.affiliation: a Department of Congenital Cardiac Defects , Institute of Cardiology , Warsaw , Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Hoffman
mesh_terms: D000328:Adult; D000069278:Arterial Switch Operation / Q000009:adverse effects*; D016022:Case-Control Studies; D004562:Electrocardiography; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D011044:Poland; D049590:Postpartum Period; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000209:etiology*; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D014188:Transposition of Great Vessels / Q000150:complications*; D055815:Young Adult
keywords: Cardiac complication; congenital heart disease; obstetric/neonatal outcome