title: Association of Age and Lipid Profiles with Measures of Renal Function in an Iranian Population.
abstract: OBJECTIVE
  We have investigated the association between markers of renal function [serum urea nitrogen, creatinine, and estimated glomerular filtration rate (eGFR)] and age and lipid profile in an Iranian population sample of 4,567 subjects.
  
  
  METHODS
  Serum creatinine and urea nitrogen, together with anthropometric parameters and lipid profile were determined in all the subjects. eGFR was calculated using the modification of diet in renal disease formula.
  
  
  RESULTS
  Serum creatinine and urea nitrogen increased with age (p < .05), and this relationship was also more pronounced in men compared to women. Increased levels of these renal function markers were significantly associated with altered lipid profiles.
  
  
  CONCLUSIONS
  Levels of renal function markers increased with age and were associated with altered lipid profile.
authors.affiliation: a Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.|b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.|c Department of Biology, Payame Noor University , Taft , Islamic Republic of Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Mohammadi
authors.affiliation: a Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.|b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Amir
authors.initials: A
authors.lastname: Avan
authors.affiliation: b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Marzieh
authors.initials: M
authors.lastname: Emamian
authors.affiliation: d Department of Physiology, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Khajavi-Rad
authors.affiliation: b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Malihe
authors.initials: M
authors.lastname: Aghasizadeh-Sharbaf
authors.affiliation: b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Tayefi
authors.affiliation: e Biostatistics and Epidemiology, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Habibollah
authors.initials: H
authors.lastname: Esmaeili
authors.affiliation: b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Davoud
authors.initials: D
authors.lastname: Zomorrodian
authors.affiliation: f Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Moohebati
authors.affiliation: f Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Ebrahimi
authors.affiliation: a Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Mohsen
authors.initials: M
authors.lastname: Nematy
authors.affiliation: f Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Reza Azarpazhooh
authors.affiliation: b Department of Modern Sciences and Technologies, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Mina
authors.initials: M
authors.lastname: Mousavi
authors.affiliation: c Department of Biology, Payame Noor University , Taft , Islamic Republic of Iran.
authors.forename: Fatemeh
authors.initials: F
authors.lastname: Daneshmand
authors.affiliation: g Brighton & Sussex Medical School, Division of Medical Education , Falmer, Brighton , Sussex , UK.
authors.forename: Gordon A
authors.initials: GA
authors.lastname: Ferns
authors.affiliation: a Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Parizadeh
authors.affiliation: a Biochemistry of Nutrition Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.|f Cardiovascular Research Center, School of Medicine, Mashhad University of Medical Sciences , Mashhad , Iran.
authors.forename: Majid
authors.initials: M
authors.lastname: Ghayour-Mobarhan
mesh_terms: D000328:Adult; D000375:Aging / Q000502:physiology*; D015415:Biomarkers / Q000097:blood; D001806:Blood Urea Nitrogen; D015992:Body Mass Index; D003404:Creatinine / Q000097:blood; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007492:Iran; D007668:Kidney / Q000502:physiology*; D008055:Lipids / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012737:Sex Factors; D012907:Smoking
chemical_list: D015415:Biomarkers; D008055:Lipids; D003404:Creatinine
keywords: age; creatinine; lipid profile; renal function markers