title: Change in body mass index among girls with precocious puberty under treatment.
abstract: Changes in body mass index (BMI) among girls with idiopathic central precocious puberty (ICPP) under treatment have been controversial in other populations.
  
  
  
  To assess changes in BMI Z score and the rate of overweight and obesity in Mexican girls with ICPP during their first year of treatment.
  
  
  
  A retrospective study was conducted among girls with ICPP under treatment with leuprolide, with a somatometry performed every six months, over a 1-year period. An analysis of variance (ANOVA) was done to establish differences in BMI Z score and a multivariate analysis was used to assess the relationship among the different factors.
  
  
  
  Among 121 girls, BMI Z score increased from 0.87 to 1.32, and the rate of overweight and obesity increased from 40.5% to 70.3%, a statistically significant difference.
  
  
  
  Changes in BMI Z score and the rate of overweight and obesity among Mexican girls with ICPP increased significantly.
authors.affiliation: Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad (UMAE), Hospital de Pediatría Centro Médico Nacional Siglo XXI, Doctores, Ciudad de Mexico, D.F., 06720, México.|Instituto Mexicano del Seguro Social, Cuauhtémoc, Juárez, Ciudad de México, D.F., 06600, México.
authors.forename: Jessie N
authors.initials: JN
authors.lastname: Zurita Cruz
authors.affiliation: Departamento de Endocrinología Pediátrica, Hospital de Pediatría Centro Médico Nacional Siglo XXI, Doctores, Ciudad de Mexico, D.F., 06720, México.|Instituto Mexicano del Seguro Social, Cuauhtémoc, Juárez, Ciudad de México, D.F., 06600, México.
authors.forename: Irene
authors.initials: I
authors.lastname: Díaz Rodríguez
authors.affiliation: Departamento de Endocrinología Pediátrica, Hospital de Pediatría Centro Médico Nacional Siglo XXI, Doctores, Ciudad de Mexico, D.F., 06720, México.|Instituto Mexicano del Seguro Social, Cuauhtémoc, Juárez, Ciudad de México, D.F., 06600, México.
authors.forename: Elisa
authors.initials: E
authors.lastname: Nishimura Meguro
authors.affiliation: Unidad de Investigación Médica en Epidemiología Clínica, Unidad Médica de Alta Especialidad (UMAE), Hospital de Pediatría Centro Médico Nacional Siglo XXI, Doctores, Ciudad de Mexico, D.F., 06720, México.|Instituto Mexicano del Seguro Social, Cuauhtémoc, Juárez, Ciudad de México, D.F., 06600, México.
authors.forename: Miguel Á
authors.initials: MÁ
authors.lastname: Villasis Keever
authors.affiliation: Departamento de Endocrinología Pediátrica, Hospital de Pediatría Centro Médico Nacional Siglo XXI, Doctores, Ciudad de Mexico, D.F., 06720, México.|Instituto Mexicano del Seguro Social, Cuauhtémoc, Juárez, Ciudad de México, D.F., 06600, México.
authors.forename: Aleida
authors.initials: A
authors.lastname: De Jesús Rivera Hernández
authors.affiliation: Departamento de Endocrinología Pediátrica, Hospital de Pediatría Centro Médico Nacional Siglo XXI, Doctores, Ciudad de Mexico, D.F., 06720, México.|Instituto Mexicano del Seguro Social, Cuauhtémoc, Juárez, Ciudad de México, D.F., 06600, México.
authors.forename: Eulalia
authors.initials: E
authors.lastname: Garrido Magaña
mesh_terms: D015992:Body Mass Index; D002648:Child; D005260:Female; D006801:Humans; D008800:Mexico; D050177:Overweight / Q000453:epidemiology*; D063766:Pediatric Obesity / Q000453:epidemiology*; D011629:Puberty, Precocious / Q000503:physiopathology*; D012189:Retrospective Studies
keywords: Body mass index; Central precocious puberty; Leuprolide; Obesity