title: Successful Coronary Artery Bypass in Types 2M and 2N von Willebrand Disease.
abstract: von Willebrand disease is a quantitative or qualitative deficiency of von Willebrand factor (VWF) that results in a significant risk of bleeding during surgical procedures unless precautions are taken. We describe for the first time 2 patients with type 2M and type 2N von Willebrand disease, respectively, who underwent coronary artery bypass grafting. Because of their high cardiovascular risk factors, replacement therapy was given at low doses with minimal postoperative bleeding.
authors.affiliation: Laboratory of Haematology, University Hospital of Bordeaux, Bordeaux, France. Electronic address: mathieu.fiore@chu-bordeaux.fr.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Fiore
authors.affiliation: Laboratory of Haematology, University Hospital of Bordeaux, Bordeaux, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Tuffigo
authors.affiliation: Materiovigilance Unit, University Hospital of Bordeaux, Bordeaux, France.
authors.forename: Véronique
authors.initials: V
authors.lastname: Cahoreau
authors.affiliation: Cardiac Surgery Unit, University Hospital of Bordeaux, Bordeaux, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Oses
authors.affiliation: Laboratory of Haematology, University Hospital of Bordeaux, Bordeaux, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Mouton
mesh_terms: D000368:Aged; D017023:Coronary Angiography; D001026:Coronary Artery Bypass / Q000379:methods*; D003331:Coronary Vessels / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000150:complications / Q000175:diagnosis / Q000601:surgery*; D014842:von Willebrand Diseases / Q000150:complications*