title: Outcome of preterm infants born to overweight and obese mothers†.
abstract: OBJECTIVE
  To evaluate perinatal morbidity and mortality among preterm neonates who were born to overweight and obese mothers compared to preterm neonates who were born to mothers with normal pre-pregnancy body mass index (BMI).
  
  
  METHODS
  Retrospective recordings of medical charts of 110 preterm infants born to overweight (n = 68) and obese (n = 42) mothers at gestational age (GA) 28-34 weeks, as well as 110 controls matched for GA and birth weight. All infants were born at the Sheba Medical Center between 2007 and 2014. Data regarding maternal pre-pregnancy weight and height were recorded, as well as maternal and neonatal complications and feeding methods.
  
  
  RESULTS
  Obese mothers had more pregnancy-induced hypertension (52.4% versus 21.4%, p = 0.006) and caesarean section deliveries (81% versus 52.4%, p = 0.018). Overweight mothers had more gestational diabetes (20.6% versus 2.9%, p = 0.001). The study and control groups were similar on all neonatal outcome parameters. No differences between the groups were recorded throughout hospitalization with respect to Apgar score, respiratory distress and support, hypotension, cardiac manifestations, brain pathologies, infection, feeding type and total hospitalization days.
  
  
  CONCLUSIONS
  Although the maternal complications are greater among obese and overweight women, it seems that preterm infants born to these women are not at increased risk for neonatal complications.
authors.affiliation: a Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.
authors.forename: S
authors.initials: S
authors.lastname: Danieli-Gruber
authors.affiliation: a Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.|b Department of Neonatology , Edmond and Lili Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
authors.forename: A
authors.initials: A
authors.lastname: Maayan-Metzger
authors.affiliation: a Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.|b Department of Neonatology , Edmond and Lili Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
authors.forename: I
authors.initials: I
authors.lastname: Schushan-Eisen
authors.affiliation: a Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.|b Department of Neonatology , Edmond and Lili Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
authors.forename: T
authors.initials: T
authors.lastname: Strauss
authors.affiliation: a Sackler Faculty of Medicine, Tel Aviv University , Tel Aviv , Israel , and.|b Department of Neonatology , Edmond and Lili Safra Children's Hospital, Sheba Medical Center , Tel Hashomer , Israel.
authors.forename: L
authors.initials: L
authors.lastname: Leibovitch
mesh_terms: D000704:Analysis of Variance; D001724:Birth Weight; D016022:Case-Control Studies; D002585:Cesarean Section / Q000706:statistics & numerical data; D016640:Diabetes, Gestational / Q000209:etiology; D005260:Female; D005865:Gestational Age; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000209:etiology; D007231:Infant, Newborn; D007234:Infant, Premature; D008297:Male; D009765:Obesity / Q000150:complications* / Q000453:epidemiology; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology*; D047928:Premature Birth; D012189:Retrospective Studies
keywords: Maternal obesity; neonatal outcome; preterm infants