title: [Adult acute lymphoblastic leukemia: current therapies and future perspectives].
abstract: There was no significant improvement in the treatment of adult acute lymphoblastic leukemia (ALL) in the 1ast two decades of the 20th century. However, remarkable improvements in survival have been achieved since the beginning of the 21st century, employing new treatments such as those for AYA ALL based on pediatric protocols and Ph+ ALL chemotherapies combining imatinib with other treatments. This review introduces the frontline therapies for adult ALL and discusses the current perspectives on the treatment of this malignancy.
authors.affiliation: Department of Hematology and Oncology, Nagoya University Graduate School of Medicine.
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Hayakawa
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects / Q000627:therapeutic use*; D002986:Clinical Trials as Topic; D006801:Humans; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000188:drug therapy*; D016896:Treatment Outcome