title: Scalability of Continuous Flow Production of Metal-Organic Frameworks.
abstract: Achieving the large-scale production of metal-organic frameworks (MOFs) is crucial for their utilization in applied settings. For many MOFs, quality suffers from large-scale, batch reaction systems. We have developed continuous processes for their production which showed promise owing to their versatility and the high quality of the products. Here, we report the successful upscaling of this concept by more than two orders of magnitude to deliver unprecedented production rates and space-time-yields (STYs) while maintaining the product quality. Encouragingly, no change in the reaction parameters, obtained at small scale, was required. The production of aluminium fumarate was achieved at an STY of 97 159 kg m(-3)  day(-1) and a rate of 5.6 kg h(-1) .
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia. marta.rubio@csiro.au.
authors.forename: Marta
authors.initials: M
authors.lastname: Rubio-Martinez
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Trevor D
authors.initials: TD
authors.lastname: Hadley
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Batten
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Keri
authors.initials: K
authors.lastname: Constanti-Carey
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Tim
authors.initials: T
authors.lastname: Barton
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Dylan
authors.initials: D
authors.lastname: Marley
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Andreas
authors.initials: A
authors.lastname: Mönch
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia.
authors.forename: Kok-Seng
authors.initials: KS
authors.lastname: Lim
authors.affiliation: CSIRO, Private Bag 10, Clayton, South VIC, 3169, Australia. matthew.hill@csiro.au.|Department of Chemical Engineering, Monash University, Clayton, VIC, 3800, Australia. matthew.hill@csiro.au.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Hill
mesh_terms: D000535:Aluminum / Q000737:chemistry*; D005650:Fumarates / Q000138:chemical synthesis* / Q000737:chemistry; D009942:Organometallic Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D005650:Fumarates; D009942:Organometallic Compounds; D000535:Aluminum
keywords: aluminum fumarate; flow chemistry; metal-organic frameworks; rheology; synthetic methods