title: [Estimation of plasma 25(OH)D vitamin level in residents of Lodz].
abstract: Recent evidence for the pleiotropic differentiated effects of vitamin D, coupled with recognition that vitamin D deficiency is common, has revived interest in this hormone. Vitamin D is produced by skin exposed to ultraviolet B radiation or obtained from dietary sources, including supplements. Persons commonly at risk for vitamin D deficiency include those with inadequate sun exposure, limited oral intake, or impaired intestinal absorption.
  
  
  OBJECTIVE
  of this study was to evaluate plasma 25(OH)D level in residents of Lodz.
  
  
  METHODS
  The study included 326 residents of Lodz, 156 men and 170 women, aged 30-65 years (mean 57,25±8,24 years). The study group was divided according to the age and season. The concentration of 25-hydroxy vitamin D (25-OH-D) was assessed with the application of the LIAISON® test using chemiluminescent immunoassay (CLIA) technology.
  
  
  RESULTS
  The mean plasma level of 25(OH)D was 24,96±9,84 ng/ml in studied population and it was not significantly higher in women than men (25,24 ±3,31 ng/ml vs. 23,97±3,71 ng/ml, p>0,05); The highest 25(OH)D concentration was noted in the oldest age group (29,12±2,78 ng/ml)and in summer months (33,21±2,91 ng/ml).
  
  
  CONCLUSIONS
  The concentration of vitamin D in the plasma of residents of Lodz was significantly lower than its recommendations. Age and season of the year were the factors strongly affecting the level of 25(OH)D in studied group.
authors.affiliation: Medical University of Lodz, Poland: Department of Hygiene of Nutrition and Epidemiology.
authors.forename: Małgorzata
authors.initials: M
authors.lastname: Godala
authors.affiliation: Medical University of Lodz, Poland: Department of Internal Diseases and Nephrodiabetology.
authors.forename: Izabela
authors.initials: I
authors.lastname: Materek-Kuśmierkiewicz
authors.affiliation: Medical University of Lodz, Poland: Department of Internal Diseases and Nephrodiabetology.
authors.forename: Dariusz
authors.initials: D
authors.lastname: Moczulski
authors.affiliation: Medical University of Lodz, Poland: Department of Hygiene and Health Promotion, 5Department of Internal and Infectious Diseases.
authors.forename: Franciszek
authors.initials: F
authors.lastname: Szatko
authors.affiliation: Medical University of Lodz, Poland: Department of Hygiene and Health Promotion, 5Department of Internal and Infectious Diseases.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Gaszyńska
authors.affiliation: Faculty of Medicine University of Rzeszow, Poland.
authors.forename: Sławomir
authors.initials: S
authors.lastname: Tokarski
authors.affiliation: Medical University of Lodz, Poland: Department of Internal and Infectious Diseases.
authors.forename: Jan
authors.initials: J
authors.lastname: Kowalski
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D005260:Female; D006801:Humans; D007118:Immunoassay; D008163:Luminescent Measurements; D008297:Male; D008875:Middle Aged; D011044:Poland; D012621:Seasons; D014807:Vitamin D / Q000031:analogs & derivatives* / Q000097:blood
chemical_list: D014807:Vitamin D; C104450:25-hydroxyvitamin D
keywords: residents of Lodz; seasonal variations; vitamin D