title: Characterization and hypoglycemic activity of a β-pyran polysaccharides from bamboo shoot (Leleba oldhami Nakal) shells.
abstract: The bamboo shoot (Leleba oldhami Nakal) shell is a by-product during bamboo shoot processing. It is a cheap and available resource for dietary polysaccharides. Herein, a novel polysaccharide BSSP2a was isolated and characterized from the bamboo shoot shell polysaccharides, and it was identified as a homogeneous highly-branched beta type pyran polysaccharide with a molecular weight of 1.63×10(4)kDa, which consisted of arabinose, xylose, mannose, glucose and galactose at a molar ratio of 20.4:4.9:1:3.4:20.6. The crude polysaccharides (BSSP) from the bamboo shoots shell showed hypoglycemic activity on the high fat diet and streptozotocin induced diabetic mice in a dose-dependent manner. The administration of high dose BSSP (400mg/kg) improved body weight loss and serum insulin loss, and significantly decreased the blood glucose level, serum triglycerides as well as total cholesterol levels by 48.7%, 34.8% and 26.5%, respectively. The results highlight the potential of the bamboo shoot shell polysaccharides as a natural anti-diabetic agent.
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou 350002, Fujian, China.
authors.forename: Yafeng
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou 350002, Fujian, China.
authors.forename: Shuai
authors.initials: S
authors.lastname: Zhang
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Institute of Agricultural Engineering, Fujian Academy of Agriculture Sciences, Fuzhou 350003, China.
authors.forename: Qi
authors.initials: Q
authors.lastname: Wang
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou 350002, Fujian, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Lu
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou 350002, Fujian, China.
authors.forename: Liangmei
authors.initials: L
authors.lastname: Lin
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou 350002, Fujian, China.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Tian
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China. Electronic address: jianboxiao@yahoo.com.
authors.forename: Jianbo
authors.initials: J
authors.lastname: Xiao
authors.affiliation: College of Food Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China; Fujian Provincial Key Laboratory of Quality Science and Processing Technology in Special Starch, Fuzhou 350002, Fujian, China. Electronic address: zbdfst@163.com.
authors.forename: Baodong
authors.initials: B
authors.lastname: Zheng
mesh_terms: D000818:Animals; D031723:Bambusa / Q000737:chemistry*; D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight / Q000187:drug effects; D003921:Diabetes Mellitus, Experimental / Q000097:blood / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D007328:Insulin / Q000097:blood; D051379:Mice; D008970:Molecular Weight; D009005:Monosaccharides / Q000032:analysis; D018520:Plant Shoots / Q000737:chemistry*; D011134:Polysaccharides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology* / Q000627:therapeutic use; D011714:Pyrans / Q000737:chemistry*; D014280:Triglycerides / Q000097:blood
chemical_list: D001786:Blood Glucose; D007004:Hypoglycemic Agents; D007328:Insulin; D009005:Monosaccharides; D011134:Polysaccharides; D011714:Pyrans; D014280:Triglycerides
keywords: Bamboo shoot shells; Hypoglycemic activity; Polysaccharides; Structural characterization