title: The influence of the representation of collagen fibre organisation on the cartilage contact mechanics of the hip joint.
abstract: The aim of this study was to develop a finite element (FE) hip model with subject-specific geometry and biphasic cartilage properties. Different levels of detail in the representation of fibre reinforcement were considered to evaluate the feasibility to simplify the complex depth-dependent fibre pattern in the native hip joint. A FE model of a cadaveric hip with subject-specific geometry was constructed through micro-computed-tomography (µCT) imaging. The cartilage was assumed to be biphasic and fibre-reinforced with different levels of detail in the fibre representation. Simulations were performed for heel-strike, mid-stance and toe-off during walking and one-leg-stance over 1500s. It was found that the required level of detail in fibre representation depends on the parameter of interest. The contact stress of the native hip joint could be realistically predicted by simplifying the fibre representation to being orthogonally reinforced across the whole thickness. To predict the fluid pressure, depth-dependent fibre organisation is needed but specific split-line pattern on the surface of cartilage is not necessary. Both depth-dependent and specific surface fibre orientations are required to simulate the strains.
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK. Electronic address: ljyjerry@gmail.com.
authors.forename: Junyan
authors.initials: J
authors.lastname: Li
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK.
authors.forename: Xijin
authors.initials: X
authors.lastname: Hua
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK.
authors.forename: Alison C
authors.initials: AC
authors.lastname: Jones
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK.
authors.forename: Sophie
authors.initials: S
authors.lastname: Williams
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK; School of Mechanical Engineering, Xi'an Jiaotong University, China.
authors.forename: Zhongmin
authors.initials: Z
authors.lastname: Jin
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK.
authors.forename: John
authors.initials: J
authors.lastname: Fisher
authors.affiliation: Institute of Medical and Biological Engineering, School of Mechanical Engineering, University of Leeds, UK.
authors.forename: Ruth K
authors.initials: RK
authors.lastname: Wilcox
mesh_terms: D002358:Cartilage, Articular / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D003094:Collagen / Q000502:physiology*; D020342:Finite Element Analysis; D006621:Hip Joint / Q000033:anatomy & histology / Q000000981:diagnostic imaging / Q000502:physiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D016138:Walking / Q000502:physiology; D055114:X-Ray Microtomography
chemical_list: D003094:Collagen
keywords: Articular cartilage; Biphasic; Collagen fibre; Contact mechanics; Finite element