title: [Determination of Plasticizer DEHP Released from Medical Injection Equipment].
abstract: To established an effective GC-MS /MS method for the contents determination of the residual DEHP in injection equipment, and investigate the effect of the pretreatment on the measurement. To simulate the clinical conditions of use, under the condition of 37 degrees C balance extraction, extract liquor by chloroform extraction, then the extract followed by analysis of GC-MS /MS. The method was simple, rapid, sensitive and accurate. The limits of quantitation (LOQ, S/N = 5) of cyclohexanone was 0.075 μg/mL, The spiked average recoveries ranged from 92% to 98%. The relative standard deviations (RSDs) of the method ranged from 1.01% to 1.61%, The method was simple, fast, sensitive and accurate, and may serve as a mass control method for residual DEHP in injection equipment.
authors.forename: Jian
authors.initials: J
authors.lastname: Zheng
authors.forename: Minzhu
authors.initials: M
authors.lastname: Wang
authors.lastname: Wang Anyan
authors.forename: Pinghua
authors.initials: P
authors.lastname: Xu
authors.forename: Yin
authors.initials: Y
authors.lastname: Han
authors.forename: Yan
authors.initials: Y
authors.lastname: Wen
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
mesh_terms: D003512:Cyclohexanones / Q000737:chemistry; D004051:Diethylhexyl Phthalate / Q000737:chemistry*; D004866:Equipment Contamination; D008401:Gas Chromatography-Mass Spectrometry; D007267:Injections / Q000295:instrumentation; D057230:Limit of Detection; D010968:Plasticizers / Q000737:chemistry*
chemical_list: D003512:Cyclohexanones; D010968:Plasticizers; C036468:cyclohexanone; D004051:Diethylhexyl Phthalate