title: Use of ustekinumab for severe refractory atopic dermatitis in a young teenager.
abstract: When conventional systemic immunosuppressive treatments fail in the setting of severe eczema, unlike in psoriasis, there are limited treatment options and only anecdotal evidence to help guide clinicians. There is a growing body of evidence for the use of certain biologic agents for moderate to severe eczema. We report the youngest case to date successfully and safely treated with ustekinumab for severe refractory atopic dermatitis.
authors.affiliation: Department of Dermatology, Bristol Children's Hospital, Bristol, UK.
authors.forename: C
authors.initials: C
authors.lastname: Wlodek
authors.affiliation: Department of Dermatology, Bristol Children's Hospital, Bristol, UK.
authors.forename: H
authors.initials: H
authors.lastname: Hewitt
authors.affiliation: Department of Dermatology, Bristol Children's Hospital, Bristol, UK.
authors.forename: C T
authors.initials: CT
authors.lastname: Kennedy
mesh_terms: D000293:Adolescent; D000911:Antibodies, Monoclonal / Q000627:therapeutic use*; D003876:Dermatitis, Atopic / Q000188:drug therapy*; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D007279:Injections, Subcutaneous / Q000379:methods*; D011239:Prednisolone / Q000008:administration & dosage / Q000627:therapeutic use; D011788:Quality of Life; D016896:Treatment Outcome; D000069549:Ustekinumab / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D000911:Antibodies, Monoclonal; D007166:Immunosuppressive Agents; D011239:Prednisolone; D000069549:Ustekinumab