title: Striking Difference between Succinimidomethyl and Phthalimidomethyl Radicals in Conjugate Addition to Alkylidenemalonate Initiated by Dimethylzinc.
abstract: We used dimethylzinc to develop a conjugate addition reaction of imidomethyl radicals to alkylidenemalonates, in which we observed a significant difference between succinimidomethyl and phthalimidomethyl radicals. This reaction provides new access to γ-aminobutyric acid derivatives, which often function as neurotransmitters.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University Yoshida , Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Ken-Ichi
authors.initials: K
authors.lastname: Yamada
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University Yoshida , Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsumoto
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University Yoshida , Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Shintaro
authors.initials: S
authors.lastname: Fujii
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University Yoshida , Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Takehito
authors.initials: T
authors.lastname: Konishi
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University Yoshida , Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Yousuke
authors.initials: Y
authors.lastname: Yamaoka
authors.affiliation: Graduate School of Pharmaceutical Sciences, Kyoto University Yoshida , Sakyo-ku, Kyoto 606-8501, Japan.
authors.forename: Kiyosei
authors.initials: K
authors.lastname: Takasu