title: Antibiotic Resistance Profiles and Genetic Similarities Within a New Generation of Carbapenem-Resistant Acinetobacter calcoaceticus-A. baumannii Complex Resistotypes in Bosnia and Herzegovina.
abstract: Acinetobacter calcoaceticus-A. baumannii complex (ACB complex) is a nosocomial pathogen. Due to its high ability to develop antibiotic resistance, it has become a problematic challenge in the modern healthcare system. The molecular and genetic mechanisms of gaining multidrug resistance in ACB complex are well known. This study focuses on providing an overview of the antibiotic resistance profiles, genetic similarities and resistotypes, and general characteristics of carbapenem-resistant ACB complex (CRACB) in Bosnia and Herzegovina (BiH). In light of the data collected in this study, together with the already known information concerning antibiotic resistance of ACB complex, we intend to further elucidate the antibiotic therapy for CRACB strain resistotypes in BiH.
authors.affiliation: 1 Biology Education, Ishik University , Erbil, Iraq .
authors.forename: Aydin
authors.initials: A
authors.lastname: Çöl
authors.affiliation: 2 Clinical Microbiology, Clinical Center University of Sarajevo , Sarajevo, Bosnia and Herzegovina.
authors.forename: Amela
authors.initials: A
authors.lastname: Dedeić-Ljubović
authors.affiliation: 2 Clinical Microbiology, Clinical Center University of Sarajevo , Sarajevo, Bosnia and Herzegovina.
authors.forename: Irma
authors.initials: I
authors.lastname: Salimović-Bešić
authors.affiliation: 3 Genetics and Bioengineering, International Burch University , Sarajevo, Bosnia and Herzegovina.
authors.forename: Mirsada
authors.initials: M
authors.lastname: Hukic
mesh_terms: D000151:Acinetobacter Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D040981:Acinetobacter baumannii / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D016954:Acinetobacter calcoaceticus / Q000145:classification / Q000187:drug effects / Q000235:genetics* / Q000302:isolation & purification; D000617:Aminoglycosides / Q000494:pharmacology; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D015373:Bacterial Typing Techniques; D017522:Bosnia and Herzegovina / Q000453:epidemiology; D015780:Carbapenems / Q000494:pharmacology; D002999:Clone Cells; D003428:Cross Infection / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D024901:Drug Resistance, Multiple, Bacterial / Q000235:genetics*; D006801:Humans; D010802:Phylogeny; D015662:Trimethoprim, Sulfamethoxazole Drug Combination / Q000494:pharmacology; D018440:beta-Lactam Resistance / Q000235:genetics*
chemical_list: D000617:Aminoglycosides; D000900:Anti-Bacterial Agents; D015780:Carbapenems; D015662:Trimethoprim, Sulfamethoxazole Drug Combination
keywords: ACB complex; Bosnia; antibiotic resistance; carbapenem-resistant Acinetobacter; genetic similarities; resistotypes