title: Active Hip Flexion is a predictor of mobility in Amyotrophic Lateral Sclerosis.
abstract: BACKGROUND
  Muscle Force (MF) and amplitude of active movement (AAM) are progressively affected in amyotrophic lateral sclerosis (ALS). These measurements are correlated with mobility but influence it in a distinct manner.
  
  
  OBJECTIVE
  To determine the influence of MF and AAM on the mobility of the subjects with ALS.
  
  
  METHODS
  The formula for identifying the covariables and scale of mobility of the Amyotrophic Lateral Sclerosis Assessment Questionnaire were applied to 23 subjects with ALS. The MF data of the knee and ankle flexors and extensors were collected in the most affected limb. In conjunction, the AAM of hip and knee flexion were captured. Multiple linear regressions were used, considering alpha ≤0.05.
  
  
  RESULTS
  MF and AAM interfered in mobility and are responsible for 63.6% of the variation in mobility. The variable that explained this variation was the AAM of hip flexion. The stage of disease was considered a covariable.
  
  
  CONCLUSIONS
  AAM of hip flexion is a safe predictor of mobility in ALS. Retarding loss of this AAM may maintain these subjects functional for a longer time. It was not possible to use MF of the muscles evaluated to predict mobility.
authors.affiliation: Functional Electrostimulation Laboratory, Biomorphology Department, Federal University of Bahia, Salvador, Brazil.|Federal University of Bahia, University Hospital of the Federal University of Bahia, Salvador, Brazil.
authors.forename: Cleber Luz
authors.initials: CL
authors.lastname: Santos
authors.affiliation: Functional Electrostimulation Laboratory, Biomorphology Department, Federal University of Bahia, Salvador, Brazil.|Federal University of Bahia, University Hospital of the Federal University of Bahia, Salvador, Brazil.
authors.forename: Diana Oliveira
authors.initials: DO
authors.lastname: Noronha
authors.affiliation: Functional Electrostimulation Laboratory, Biomorphology Department, Federal University of Bahia, Salvador, Brazil.
authors.forename: Paulo Itamar Ferraz
authors.initials: PI
authors.lastname: Lessa
authors.affiliation: Health Sciences Department, Federal University of Bahia, Salvador, Brazil.
authors.forename: Janine Ribeiro
authors.initials: JR
authors.lastname: Camatti
authors.affiliation: Health Sciences Department, Federal University of Bahia, Salvador, Brazil.
authors.forename: Iasmyn Adélia
authors.initials: IA
authors.lastname: Victor de Oliveira Fernandes
authors.affiliation: Functional Electrostimulation Laboratory, Biomorphology Department, Federal University of Bahia, Salvador, Brazil.
authors.forename: Alaí
authors.initials: A
authors.lastname: Barbosa Paixão
authors.affiliation: Functional Electrostimulation Laboratory, Biomorphology Department, Federal University of Bahia, Salvador, Brazil.|Bahian School of Medicine and Public Health, Salvador, Brazil.
authors.forename: Kátia Nunes
authors.initials: KN
authors.lastname: Sá
authors.affiliation: Functional Electrostimulation Laboratory, Biomorphology Department, Federal University of Bahia, Salvador, Brazil.|Federal University of Rio de Janeiro, Salvador, Brazil.
authors.forename: Abrahão Fontes
authors.initials: AF
authors.lastname: Baptista
authors.affiliation: Federal University of Bahia, University Hospital of the Federal University of Bahia, Salvador, Brazil.
authors.forename: Rita de Cássia Saldanha
authors.initials: Rde C
authors.lastname: de Lucena
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000690:Amyotrophic Lateral Sclerosis / Q000503:physiopathology*; D000843:Ankle Joint / Q000503:physiopathology; D005260:Female; D006621:Hip Joint / Q000503:physiopathology*; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009068:Movement; D016059:Range of Motion, Articular / Q000502:physiology*
keywords: Amyotrophic Lateral Sclerosis; limitation of mobility; muscle force