title: Red blood cell transfusion to treat or prevent complications in sickle cell disease: an overview of Cochrane reviews.
abstract: This is the protocol for a review and there is no abstract. The objectives are as follows: To summarize the evidence in Cochrane reviews of the effectiveness and safety of red cell transfusions versus no transfusion, or restrictive (to increase the total haemoglobin) versus liberal (to decrease the haemoglobin S level below a specified percentage) transfusion, for treatment or prevention of complications experienced by people with SCD.
authors.affiliation: Haematology/Transfusion Medicine, NHS Blood and Transplant, Oxford, UK.
authors.forename: Lise J
authors.initials: LJ
authors.lastname: Estcourt
authors.affiliation: Systematic Review Initiative, NHS Blood and Transplant, Oxford, UK.
authors.forename: Patricia M
authors.initials: PM
authors.lastname: Fortin
authors.affiliation: Oxford Clinical Trials Research Unit, University of Oxford, Oxford, UK.
authors.forename: Sally
authors.initials: S
authors.lastname: Hopewell
authors.affiliation: Centre for Statistics in Medicine, University of Oxford, Oxford, UK.
authors.forename: Marialena
authors.initials: M
authors.lastname: Trivella