title: Recommendations of the German Central Committee against Tuberculosis (DZK) and the German Respiratory Society (DGP) for the Diagnosis and Treatment of Non-tuberculous Mycobacterioses.
abstract: Non-tuberculous mycobacterioses comprise a group of diseases caused by mycobacteria which do not belong to the Mycobacterium (M.) tuberculosis-complex and are not ascribed to M. leprae. These mycobacteria are characterized by a broad variety as to environmental distribution and adaptation. Some of the species may cause specific diseases, especially in patients with underlying immunosuppressive diseases, chronic pulmonary diseases or genetic predisposition, respectively. Worldwide, a rising prevalence and significance of non-tuberculous mycobacterioses is recognized. The present recommendations summarise current aspects of epidemiology, pathogenesis, clinical aspects, diagnostics - especially microbiological methods including susceptibility testing -, and specific treatment for the most relevant species. Diagnosis and treatment of non-tuberculous mycobacterioses during childhood and in HIV-infected individuals are described in separate chapters.
authors.affiliation: Department of Pneumology, Lungenklinik Heckeshorn, Helios Klinikum Emil von Behring, Berlin.
authors.forename: N
authors.initials: N
authors.lastname: Schoenfeld
authors.affiliation: Department for Infectious Disease Epidemiology, Respiratory Infections Unit, Robert Koch Institute, Berlin.
authors.forename: W
authors.initials: W
authors.lastname: Haas
authors.affiliation: Head of TB laboratory; MVZ Labor Dr. Limbach & Kollegen GbR.
authors.forename: E
authors.initials: E
authors.lastname: Richter
authors.affiliation: Department of Pneumology, Lungenklinik Heckeshorn, Helios Klinikum Emil von Behring, Berlin.
authors.forename: T
authors.initials: T
authors.lastname: Bauer
authors.affiliation: German Central Committee against Tuberculosis, Berlin.
authors.forename: L
authors.initials: L
authors.lastname: Boes
authors.affiliation: German Central Committee against Tuberculosis, Berlin.
authors.forename: S
authors.initials: S
authors.lastname: Castell
authors.affiliation: Department for Infectious Disease Epidemiology, Respiratory Infections Unit, Robert Koch Institute, Berlin.
authors.forename: B
authors.initials: B
authors.lastname: Hauer
authors.affiliation: Department of Pediatrics, Subspecialty Pneumology and Immunology, Charité Universitäts-Medizin Berlin, Stiftung Oskar-Helene-Heim, Berlin.
authors.forename: K
authors.initials: K
authors.lastname: Magdorf
authors.affiliation: Coswig Specialist Hospital, Center for Pneumology and Thoracic Surgery.
authors.forename: W
authors.initials: W
authors.lastname: Matthiessen
authors.affiliation: Department of Microbiology, Immunology and Laboratory Medicine, Helios Klinikum Emil von Behring, Berlin.
authors.forename: H
authors.initials: H
authors.lastname: Mauch
authors.affiliation: Department for Infectious Disease Epidemiology, Respiratory Infections Unit, Robert Koch Institute, Berlin.
authors.forename: A
authors.initials: A
authors.lastname: Reuss
authors.affiliation: German Central Committee against Tuberculosis, Berlin.
authors.forename: K
authors.initials: K
authors.lastname: Schenkel
authors.affiliation: Microbiologist consultant, Reinbek, member of the WHO GLI Europe.
authors.forename: S
authors.initials: S
authors.lastname: Ruesch-Gerdes
authors.affiliation: Research Center Borstel, Medical Clinic, Borstel.
authors.forename: P
authors.initials: P
authors.lastname: Zabel
authors.affiliation: Department of Medicine III (Pulmonology), University Hospital of Schleswig-Holstein, Luebeck Campus.
authors.forename: K
authors.initials: K
authors.lastname: Dalhoff
authors.affiliation: Center for Pneumology, Agaplesion Diakonie Hospital, Rotenburg.
authors.forename: T
authors.initials: T
authors.lastname: Schaberg
authors.affiliation: German Central Committee against Tuberculosis, Berlin.
authors.forename: R
authors.initials: R
authors.lastname: Loddenkemper
mesh_terms: D003948:Diagnostic Techniques, Respiratory System / Q000592:standards*; D019317:Evidence-Based Medicine; D005858:Germany; D006801:Humans; D055552:Infectious Disease Medicine / Q000592:standards*; D009165:Mycobacterium Infections, Nontuberculous / Q000175:diagnosis* / Q000382:microbiology / Q000628:therapy*; D017410:Practice Guidelines as Topic; D015272:Pulmonary Medicine / Q000592:standards*; D016896:Treatment Outcome