title: Developments in urologic oncology «OncoForum»: The best of 2015.
abstract: OBJECTIVE
  To review the latest evidence on the oncologic urology of prostate, renal and bladder tumours, analysing their impact on daily clinical practice and future medium to long-term regimens.
  
  
  METHODS
  We review the abstracts on prostate, renal and bladder cancer presented at the 2015 congresses (EAU, AUA, ASCO, ESMO y ASTRO) that received the best evaluations by the OncoForum committee.
  
  
  RESULTS
  Cabozantinib could represent a new second-line (or subsequent) treatment option for patients with advanced renal cancer. In muscle-invasive bladder cancer, the genetic expression profile could predict the clinical benefit of neoadjuvant therapy in treating urothelial tumours. In metastatic castration-resistant prostate cancer, results were presented from various studies that evaluated the addition of chemotherapy to standard treatment with androgen deprivation, showing a reduction in the progression risk and higher PSA response rates.
  
  
  CONCLUSIONS
  New options for the second-line treatment of renal cancer were presented. In metastatic castration-resistant prostate cancer, various studies have been published on treatment with enzalutamide, which has been shown to delay the symptomatic disease and benefit overall survival.
authors.affiliation: Servicio de Urología, Hospital Universitario de Salamanca, Grupo de Investigación Traslacional de Urología (GITUR), Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, España. Electronic address: fgveiga@telefonica.net.
authors.forename: F
authors.initials: F
authors.lastname: Gómez-Veiga
authors.affiliation: Servicio de Urología, Hospital Clínic Universitari, Barcelona, España.
authors.forename: A
authors.initials: A
authors.lastname: Alcaraz-Asensio
authors.affiliation: Servicio de Urología, Hospital Universitario Ramón y Cajal, Madrid, España.
authors.forename: J
authors.initials: J
authors.lastname: Burgos-Revilla
authors.affiliation: Servicio de Urología, Complejo Hospitalario Universitario de Granada, Granada, España.
authors.forename: J
authors.initials: J
authors.lastname: Cózar-Olmo
mesh_terms: D001706:Biopsy; D006801:Humans; D007680:Kidney Neoplasms / Q000628:therapy; D008297:Male; D008495:Medical Oncology; D009362:Neoplasm Metastasis; D009367:Neoplasm Staging; D011471:Prostatic Neoplasms / Q000473:pathology / Q000628:therapy; D001749:Urinary Bladder Neoplasms / Q000628:therapy; D014572:Urology
keywords: Bladder cancer; Cáncer de próstata; Cáncer de vejiga; Cáncer renal; Oncologic urology.; Oncourología; Prostate cancer; Renal cancer; Urologic oncology; Urooncología