title: First case of yellow fever vaccine-associated viscerotropic disease (YEL-AVD) in Hong Kong.
abstract: Yellow fever is an important and potentially fatal infection in tropical regions of Africa, South America, eastern Panama in Central America and Trinidad in the Caribbean. Yellow fever vaccination is not only crucial to reduce the disease risk and mortality in individuals travelling to these areas, but also an important public health measure to prevent the spread of the disease. Despite generally considered as a safe vaccine, yellow fever vaccine can rarely be associated with severe adverse reactions including yellow fever vaccine-associated viscerotropic disease (YEL-AVD). Here, we report the first case of YEL-AVD in Hong Kong. Clinicians should alert to the possibility of YEL-AVD in vaccinees presenting with compatible symptoms after yellow fever vaccination, particularly in people at higher risk of adverse events.
authors.affiliation: Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China leungws4@ha.org.hk.
authors.forename: Wai Shing
authors.initials: WS
authors.lastname: Leung
authors.affiliation: Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China.
authors.forename: Man Chun
authors.initials: MC
authors.lastname: Chan
authors.affiliation: Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China.
authors.forename: Shiu Hong
authors.initials: SH
authors.lastname: Chik
authors.affiliation: Department of Medicine and Geriatrics, Princess Margaret Hospital, Hong Kong, China.
authors.forename: Tak Yin
authors.initials: TY
authors.lastname: Tsang
mesh_terms: D000368:Aged; D006723:Hong Kong; D006801:Humans; D008297:Male; D017410:Practice Guidelines as Topic; D014195:Travel; D014611:Vaccination / Q000009:adverse effects*; D014944:World Health Organization; D015004:Yellow Fever / Q000517:prevention & control; D022341:Yellow Fever Vaccine / Q000009:adverse effects*
chemical_list: D022341:Yellow Fever Vaccine
keywords: Hong Kong; Yellow fever vaccination; viscerotropic disease