title: Serum Lactate Dehydrogenase in Non-Hodgkin's Lymphoma: A Prognostic Indicator.
abstract: Non-Hodgkin's lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50-75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin's lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).
authors.affiliation: Department of Biochemistry, Kasturba Medical College, Manipal University, Mangalore, 575004 India.
authors.forename: Charu
authors.initials: C
authors.lastname: Yadav
authors.affiliation: Department of Biochemistry, Kasturba Medical College, Manipal University, Mangalore, 575004 India.
authors.forename: Afzal
authors.initials: A
authors.lastname: Ahmad
authors.affiliation: Department of Biochemistry, Kasturba Medical College, Manipal University, Mangalore, 575004 India.
authors.forename: Benedicta
authors.initials: B
authors.lastname: D'Souza
authors.affiliation: Department of Biochemistry, Kasturba Medical College, Manipal University, Mangalore, 575004 India.
authors.forename: Ashish
authors.initials: A
authors.lastname: Agarwal
authors.affiliation: Department of Biochemistry, Kasturba Medical College, Manipal University, Mangalore, 575004 India.
authors.forename: M
authors.initials: M
authors.lastname: Nandini
authors.affiliation: Department of Biochemistry, Kasturba Medical College, Manipal University, Mangalore, 575004 India.
authors.forename: K
authors.initials: K
authors.lastname: Ashok Prabhu
authors.affiliation: Department of Biochemistry, Kanachur Institute of Medical Science, Deralakatte, Mangalore, India.
authors.forename: Vivian
authors.initials: V
authors.lastname: D'Souza
keywords: Lactate dehydrogenase (LDH); Non-Hodgkin’s lymphoma (NHL)