title: Interfering with CCL5/CCR5 at the Tumor-Stroma Interface.
abstract: In this issue of Cancer Cell, Halama et al. (2016) further advance chemokine interference as a therapeutic option for cancer by demonstrating the effect of CCR5 blockade in reshaping macrophage polarization toward an anti-tumor functional state in patient-derived tumor models and liver metastases of colorectal cancer patients.
authors.affiliation: Immunology, Department of Medicine, Verona University Hospital, Verona 37134, Italy. Electronic address: vincenzo.bronte@univr.it.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bronte
authors.affiliation: Medical Oncology, Department of Medicine, Verona University Hospital, Verona 37134, Italy.
authors.forename: Emilio
authors.initials: E
authors.lastname: Bria
mesh_terms: D018946:Chemokine CCL5; D015179:Colorectal Neoplasms; D006801:Humans; D019713:Receptors, CCR5; D012983:Soft Tissue Neoplasms
chemical_list: D018946:Chemokine CCL5; D019713:Receptors, CCR5