title: Polymorphic variants of the HSD11B1 gene may be involved in adverse metabolic effects of glucocorticoid replacement therapy in Addison's disease.
authors.affiliation: Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego, 60-355 Poznan, Poland; Institute of Human Genetics, Polish Academy of Sciences, 32 Strzeszynska, 60-479 Poznan, Poland; Department of Clinical Immunology, Poznan University of Medical Sciences, 5d Rokietnicka, 60-805 Poznan, Poland. Electronic address: mfichna@man.poznan.pl.
authors.forename: Marta
authors.initials: M
authors.lastname: Fichna
authors.affiliation: Institute of Human Genetics, Polish Academy of Sciences, 32 Strzeszynska, 60-479 Poznan, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Żurawek
authors.affiliation: Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego, 60-355 Poznan, Poland.
authors.forename: Maria
authors.initials: M
authors.lastname: Gryczyńska
authors.affiliation: Department of Computer Science and Statistics, Poznan University of Medical Sciences, 79 Dabrowskiego, 60-529 Poznan, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Sowińska
authors.affiliation: Institute of Human Genetics, Polish Academy of Sciences, 32 Strzeszynska, 60-479 Poznan, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Nowak
authors.affiliation: Department of Endocrinology, Metabolism and Internal Medicine, Poznan University of Medical Sciences, 49 Przybyszewskiego, 60-355 Poznan, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Ruchała
mesh_terms: D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1 / Q000235:genetics*; D000224:Addison Disease / Q000188:drug therapy* / Q000235:genetics*; D000328:Adult; D015992:Body Mass Index; D002784:Cholesterol / Q000097:blood; D003430:Cross-Sectional Studies; D005260:Female; D005838:Genotype; D005938:Glucocorticoids / Q000009:adverse effects* / Q000627:therapeutic use; D006801:Humans; D016015:Logistic Models; D008297:Male; D024821:Metabolic Syndrome / Q000453:epidemiology*; D008875:Middle Aged; D011044:Poland; D011110:Polymorphism, Genetic; D014280:Triglycerides / Q000097:blood
chemical_list: D005938:Glucocorticoids; D014280:Triglycerides; D002784:Cholesterol; D043205:11-beta-Hydroxysteroid Dehydrogenase Type 1; C468386:HSD11B1 protein, human
keywords: 11β-Hydroxysteroid dehydrogenase type 1; Addison's disease; Glucocorticoid replacement; Metabolic syndrome; Polymorphism