title: [Diagnosis Values of Back Propagation Neural Network Integrating Age, Transrectal Ultrasound Characteristics and Serum PSA for Prostate Cancer].
abstract: OBJECTIVE
  To explore the diagnosis value of back propagation (BP) neural network integrating age, transrectal ultrasound characteristics and serum prostate specific antigen (PSA) for prostate cancer.
  
  
  METHODS
  The data of age, PSA, and transrectal ultrasound characteristics were collected from 941 patients who received color doppler transrectal ultrasound scan and systemic biopsies of prostates. A prostate cancer diagnosis system of BP neural network with age, transrectal ultrasound characteristics and serum PSA was developed in MATLAB software, and its diagnostic value for prostate cancer was analyzed based on the pathological results of prostatic biopsy.
  
  
  RESULTS
  The biopsy results confirmed 358 cases of prostate cancer (38.04%) and 583 cases noncancerous prostate diseases (61.96%). The sensitivity, specificity, accuracy, positive value and negative predictive value of BP neural networks for prostate cancer diagnosis were 78.57%, 92.94%, 87.23%, 88.00% and 86.81% respectively.
  
  
  CONCLUSIONS
  Back propagation neural network with age, transrectal ultrasound characteristics and PSA shows good diagnosis value for prostate cancer.
authors.forename: Liang-cheng
authors.initials: LC
authors.lastname: Xiang
authors.forename: Li-hong
authors.initials: LH
authors.lastname: Xiao
authors.forename: Mei
authors.initials: M
authors.lastname: Li
authors.forename: Ju-hong
authors.initials: JH
authors.lastname: Mou
authors.forename: Hai-ping
authors.initials: HP
authors.lastname: Wang
authors.forename: Wei
authors.initials: W
authors.lastname: Zhang
authors.forename: Ping
authors.initials: P
authors.lastname: Feng
mesh_terms: D001706:Biopsy; D006801:Humans; D008297:Male; D016571:Neural Networks, Computer; D017430:Prostate-Specific Antigen / Q000097:blood*; D011471:Prostatic Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging; D012680:Sensitivity and Specificity; D012984:Software; D018615:Ultrasonography, Doppler, Color
chemical_list: D017430:Prostate-Specific Antigen