title: Formal Total Synthesis of (±)-Cephalotaxine and Congeners via Aryne Insertion Reaction.
abstract: The formal total synthesis of pentacyclic core alkaloid, (±)-cephalotaxine is achieved in nine steps from known 2-allylpyrrolidine-2-carboxaldehyde using aryne insertion reaction as a key step in 10% overall yield. The developed novel strategy enabled easy access to cephalotaxine congeners.
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007, India.
authors.forename: Pashikanti
authors.initials: P
authors.lastname: Gouthami
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007, India.
authors.forename: Rambabu
authors.initials: R
authors.lastname: Chegondi
authors.affiliation: Division of Natural Products Chemistry, CSIR-Indian Institute of Chemical Technology , Hyderabad 500007, India.
authors.forename: Srivari
authors.initials: S
authors.lastname: Chandrasekhar