title: Cerebral venous thrombosis presenting with intracerebral hemorrhage in a patient with paroxysmal nocturnal hemoglobinuria.
abstract: Cerebral venous thrombosis (CVT) is an uncommon cause of stroke. Paroxysmal nocturnal hemoglobinuria (PNH) is a rare type of hemolytic anemia, frequently associated with thrombophilia. PNH may rarely present with CVT. Approximately, one-third of the patients with CVT develop cerebral hemorrhage. Here, we present a rare combination of CVT presenting with intracerebral hemorrhage in a patient with PNH. High index of suspicion is needed to avoid misdiagnosis. Patient was successfully managed with anticoagulation therapy.
authors.affiliation: Department of Anaesthesiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
authors.forename: Gentle Sunder
authors.initials: GS
authors.lastname: Shrestha
authors.affiliation: Department of Internal Medicine, Civil Service Hospital, Kathmandu, Nepal.
authors.forename: Bishesh Sharma
authors.initials: BS
authors.lastname: Poudyal
authors.affiliation: Department of General Surgery, Neurosurgery Unit, Institute of Medicine, Tribhuvan University Teaching Hospital, Kathmandu, Nepal.
authors.forename: Gopal
authors.initials: G
authors.lastname: Sedain
authors.affiliation: Department of Internal Medicine, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, England.
authors.forename: Khandokar Imran
authors.initials: KI
authors.lastname: Mahmud
authors.affiliation: Department of Internal Medicine, Civil Service Hospital, Kathmandu, Nepal.
authors.forename: Niranja
authors.initials: N
authors.lastname: Acharya
keywords: Cerebral venous thrombosis; intracerebral hemorrhage; paroxysmal nocturnal hemoglobinuria