title: Cardiac Manifestations of Twin-to-Twin Transfusion Syndrome.
abstract: This review addresses the physiology of monochorionic diamniotic (MC/DA) twins and the potential for twin-twin transfusion syndrome (TTTS). It focuses on the underlying cardiovascular pathophysiology of TTTS and the cardiovascular impact of TTTS for both the recipient and the donor twin. It explains the principles for assessment and monitoring of these cardiovascular changes and how these may be used to guide pregnancy management. Finally, it describes the effect of treatment on the altered hemodynamics and how this can influence pregnancy and perinatal management, as well as longer-term follow-up.
authors.affiliation: Fetal Cardiology,Oxford University Hospitals,Oxford,UK.
authors.forename: Nicky
authors.initials: N
authors.lastname: Manning
authors.affiliation: Fetal Cardiology,Oxford University Hospitals,Oxford,UK.
authors.forename: Nick
authors.initials: N
authors.lastname: Archer
mesh_terms: D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000209:etiology / Q000503:physiopathology*; D005260:Female; D005330:Fetofetal Transfusion / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D006439:Hemodynamics; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000453:epidemiology / Q000503:physiopathology*; D059285:Pregnancy, Twin; D014430:Twins, Monozygotic
keywords: cardiac function; cardiomyopathy; monochorionic twins; outflow tract obstruction; twin–twin transfusion syndrome