title: Nonalcoholic Fatty Liver Disease and Liver Transplantation.
abstract: Nonalcoholic fatty liver disease (NAFLD) is prevalent in the general population and a growing indication for liver transplant. Longer wait times and challenges with pretransplant survivorship are expected, underscoring the need for improved management of attendant comorbidities. Recognition with potential modification of obesity, sarcopenia, chronic kidney disease, and cardiovascular disease in patients with NAFLD may have important implications in the pretransplant and posttransplant periods. Although patients with NAFLD have generally favorable postoperative outcomes, they are at risk for developing recurrent disease in their allograft, driving the need for pharmacotherapies and dietary innovations appropriate for use in the posttransplant period.
authors.affiliation: Division of Gastroenterology and Hepatology, University of Utah, 30 N 1900 E, Salt Lake City, UT 84132, USA.
authors.forename: Tuan
authors.initials: T
authors.lastname: Pham
authors.affiliation: Department of Pharmacy, Intermountain Medical Center, 5121 South Cottonwood Street, Murray, UT 84107-5701, USA.
authors.forename: Travis B
authors.initials: TB
authors.lastname: Dick
authors.affiliation: Hepatology and Liver Transplantation, Intermountain Transplant Center, Intermountain Medical Center, 5121 South Cottonwood Street, Murray, UT 84107-5701, USA. Electronic address: michael.charlton@imail.org.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Charlton
mesh_terms: D000975:Antioxidants / Q000627:therapeutic use; D015992:Body Mass Index; D001835:Body Weight; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015897:Comorbidity; D004032:Diet; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D016031:Liver Transplantation; D065626:Non-alcoholic Fatty Liver Disease / Q000453:epidemiology* / Q000601:surgery* / Q000628:therapy; D012008:Recurrence; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology*; D015996:Survival Rate; D014810:Vitamin E / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D007004:Hypoglycemic Agents; D014810:Vitamin E
keywords: Liver transplantation; Nonalcoholic fatty liver disease; Nonalcoholic steatohepatitis; The metabolic syndrome