title: [RESEARCH PROGRESS OF EXPERIMENTAL ANIMAL MODELS OF AVASCULAR NECROSIS OF FEMORAL HEAD].
abstract: OBJECTIVE
  To summarize the current researches and progress on experimental animal models of avascular necrosis of the femoral head.
  
  
  METHODS
  Domestic and internation literature concerning experimental animal models of avascular necrosis of the femoral head was reviewed and analyzed.
  
  
  RESULTS
  The methods to prepare the experimental animal models of avascular necrosis of the femoral head can be mainly concluded as traumatic methods (including surgical, physical, and chemical insult), and non-traumatic methods (including steroid, lipopolysaccharide, steroid combined with lipopolysaccharide, steroid combined with horse serum, etc). Each method has both merits and demerits, yet no ideal methods have been developed.
  
  
  CONCLUSIONS
  There are many methods to prepare the experimental animal models of avascular necrosis of the femoral head, but proper model should be selected based on the aim of research. The establishment of ideal experimental animal models needs further research in future.
authors.forename: Kaifu
authors.initials: K
authors.lastname: Yu
authors.forename: Hongbo
authors.initials: H
authors.lastname: Tan
authors.forename: Yongqing
authors.initials: Y
authors.lastname: Xu
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000473:pathology*; D001853:Bone Marrow / Q000473:pathology; D004195:Disease Models, Animal; D005270:Femur Head / Q000098:blood supply* / Q000473:pathology; D005271:Femur Head Necrosis / Q000139:chemically induced / Q000473:pathology*; D008070:Lipopolysaccharides / Q000633:toxicity*; D023421:Models, Animal
chemical_list: D008070:Lipopolysaccharides