title: Enantioselective Organocatalytic Cyclopropanation of Enals Using Benzyl Chlorides.
abstract: Herein, we describe the first enantioselective cyclopropanation of enals using benzyl chlorides as bifunctional (nucleophilic and electrophilic) reagents. The reaction is simply catalyzed by chiral secondary amines to afford the formyl cyclopropane derivatives in good yields with moderate to excellent stereoselectivities.
authors.affiliation: Faculty of Natural and Environmental Science, School of Chemistry, University of Southampton , Highfield Campus, Southampton SO17 1BJ, United Kingdom.
authors.forename: Marta
authors.initials: M
authors.lastname: Meazza
authors.affiliation: Faculty of Natural and Environmental Science, School of Chemistry, University of Southampton , Highfield Campus, Southampton SO17 1BJ, United Kingdom.
authors.forename: Maria
authors.initials: M
authors.lastname: Ashe
authors.affiliation: Department of Energy Science, Sungkyunkwan University , Suwon 440-746, South Korea.
authors.forename: Hun Yi
authors.initials: HY
authors.lastname: Shin
authors.affiliation: Department of Energy Science, Sungkyunkwan University , Suwon 440-746, South Korea.
authors.forename: Hye Sung
authors.initials: HS
authors.lastname: Yang
authors.affiliation: Department of Industrial Chemistry "Toso Montanari", School of Science, Alma Mater Studiorum-University of Bologna , V. Risorgimento 4, 40136 Bologna, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Mazzanti
authors.affiliation: Department of Energy Science, Sungkyunkwan University , Suwon 440-746, South Korea.
authors.forename: Jung Woon
authors.initials: JW
authors.lastname: Yang
authors.affiliation: Faculty of Natural and Environmental Science, School of Chemistry, University of Southampton , Highfield Campus, Southampton SO17 1BJ, United Kingdom.
authors.forename: Ramon
authors.initials: R
authors.lastname: Rios