title: Handling Big Data in Medical Imaging: Iterative Reconstruction with Large-Scale Automated Parallel Computation.
abstract: The primary goal of this project is to implement the iterative statistical image reconstruction algorithm, in this case maximum likelihood expectation maximum (MLEM) used for dynamic cardiac single photon emission computed tomography, on Spark/GraphX. This involves porting the algorithm to run on large-scale parallel computing systems. Spark is an easy-to- program software platform that can handle large amounts of data in parallel. GraphX is a graph analytic system running on top of Spark to handle graph and sparse linear algebra operations in parallel. The main advantage of implementing MLEM algorithm in Spark/GraphX is that it allows users to parallelize such computation without any expertise in parallel computing or prior knowledge in computer science. In this paper we demonstrate a successful implementation of MLEM in Spark/GraphX and present the performance gains with the goal to eventually make it useable in clinical setting.
authors.affiliation: University of North Carolina, Chapel Hill, NC 27599 USA.
authors.forename: Jae H
authors.initials: JH
authors.lastname: Lee
authors.affiliation: National Energy Research Scientific Computing (NERSC) Center, Berkeley, CA 94704 USA.
authors.forename: Yushu
authors.initials: Y
authors.lastname: Yao
authors.affiliation: Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 USA.
authors.forename: Uttam
authors.initials: U
authors.lastname: Shrestha
authors.affiliation: Structural Biology and Imaging Department, Life Sciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94704 USA.
authors.forename: Grant T
authors.initials: GT
authors.lastname: Gullberg
authors.affiliation: Physics Research Laboratory, Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA 94143 USA.
authors.forename: Youngho
authors.initials: Y
authors.lastname: Seo