title: Approaching Pharmacometrics as a Paleontologist Would: Recovering the Links Between Drugs and the Body Through Reconstruction.
abstract: Our knowledge of dinosaurs comes primarily from the fossil record. Notwithstanding the condition of these vestiges, paleontologists reconstruct early reptilian life by comparison to previously discovered specimens. When relics are missing, reasonable deductions are used to fill in the gaps.
authors.affiliation: Faculté de Pharmacie Université de Montréal Montréal QC Canada; Centre for Applied Mathematics in Bioscience and Medicine (CAMBAM) McGill University Montreal Quebec Canada.
authors.forename: M
authors.initials: M
authors.lastname: Craig
authors.affiliation: Faculté de Pharmacie Université de Montréal Montréal QC Canada; inVentiv Health Clinical Montréal Quebec Canada.
authors.forename: M
authors.initials: M
authors.lastname: González-Sales
authors.affiliation: Faculté de Pharmacie Université de Montréal Montréal QC Canada; Centre for Applied Mathematics in Bioscience and Medicine (CAMBAM) McGill University Montreal Quebec Canada.
authors.forename: J
authors.initials: J
authors.lastname: Li
authors.affiliation: Faculté de Pharmacie Université de Montréal Montréal QC Canada; Centre for Applied Mathematics in Bioscience and Medicine (CAMBAM) McGill University Montreal Quebec Canada.
authors.forename: F
authors.initials: F
authors.lastname: Nekka
mesh_terms: D003198:Computer Simulation; D004305:Dose-Response Relationship, Drug; D006410:Hematopoiesis / Q000187:drug effects; D006801:Humans; D008954:Models, Biological; D010599:Pharmacokinetics