title: Intravenous maintenance fluid therapy in children.
abstract: Intravenous fluids are frequently used in paediatrics but have been associated with significant adverse outcomes. Understanding the composition of fluid prescribed and administering an appropriate rate is essential for safe fluid administration, along with regular monitoring. Recent evidence has shown that using an isotonic fluid with a sodium concentration similar to plasma can decrease the risk of hyponatraemia without an increase in adverse effects. This should lead to a change in guidelines: isotonic fluid should now be used as the primary maintenance intravenous fluid given to the majority of children.
authors.affiliation: Department of General Medicine, The Royal Children's Hospital, Melbourne, Victoria, Australia.|Murdoch Childrens Research Institute, Melbourne, Victoria, Australia.|Department of Paediatrics, The University of Melbourne, Melbourne, Victoria, Australia.
authors.forename: Sarah
authors.initials: S
authors.lastname: McNab
mesh_terms: D002648:Child; D005440:Fluid Therapy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D007010:Hyponatremia / Q000209:etiology / Q000517:prevention & control; D007262:Infusions, Intravenous; D007552:Isotonic Solutions; D000070316:Pediatric Emergency Medicine; D012965:Sodium Chloride
chemical_list: D007552:Isotonic Solutions; D012965:Sodium Chloride
keywords: children; hydration; hypotonic; intravenous fluid; isotonic; paediatrics