title: Resolution of spontaneous hemoabdomen secondary to peliosis hepatis following surgery and azithromycin treatment in a Bartonella species infected dog.
abstract: OBJECTIVE
  To describe a case of hemoperitonium in a dog with Bartonellosis and peliosis hepatis (PH) lesions that resolved following antimicrobial therapy.
  
  
  METHODS
  A 3-year-11-month-old 22.5 kg female spayed mixed breed dog presented for progressive lethargy and vomiting. An abdominal ultrasonographic examination revealed moderate ascites, which when sampled was nonclotting hemorrhagic fluid. An exploratory laparotomy revealed a large volume of nonclotted blood in the dog's abdomen and blood-filled vesicular lesions dispersed diffusely along multiple lobes of the liver. Biopsies revealed lesions indicative of PH. Serology testing for Bartonella species was positive. Treatment with azithromycin resulted in Bartonella serology negative status and no further evidence of hemoperitonium at recheck examination 12 months after initial presentation.
  
  
  CONCLUSIONS
  This is the first reported case of PH and hemoperitoneum in a Bartonella species serology positive dog wherein treatment with azithromycin resulted in serology negative status. There have been no subsequent episodes of hemoperitoneum in the 12 months since treatment.
authors.affiliation: Oradell Animal Hospital, Paramus, NJ, 07652. sberkowitz@northstarvets.com.
authors.forename: Steven T
authors.initials: ST
authors.lastname: Berkowitz
authors.affiliation: Oradell Animal Hospital, Paramus, NJ, 07652.
authors.forename: Kristi M
authors.initials: KM
authors.lastname: Gannon
authors.affiliation: Oradell Animal Hospital, Paramus, NJ, 07652.
authors.forename: Carol A
authors.initials: CA
authors.lastname: Carberry
authors.affiliation: Oradell Animal Hospital, Paramus, NJ, 07652.
authors.forename: Yonaira
authors.initials: Y
authors.lastname: Cortes
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017963:Azithromycin / Q000008:administration & dosage / Q000627:therapeutic use*; D001474:Bartonella Infections / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000601:surgery; D004285:Dogs; D005260:Female; D006465:Hemoperitoneum / Q000175:diagnosis / Q000662:veterinary*; D010382:Peliosis Hepatis / Q000175:diagnosis / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D017963:Azithromycin
keywords: Bartonellosis; bacillary angiomatosis; hemoabdomen; peliotic