title: A lot of nexts: Next-generation sequencing, databases, and neurologists.
abstract: Whole-exome sequencing (WES) was featured prominently in the first issue of Neurology® Genetics,(1) and this technology again contributed to identification of a homozygous AMPD2 mutation as the cause of a neurodevelopmental syndrome published in this issue.(2) A different approach to analysis of a large number of exons is described by Tian and collaborators(3) and discussed by Bönnemann and colleagues,(4) both in this issue.
authors.affiliation: Department of Neurology, University of Utah, Salt Lake City.
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Pulst