title: Data in support of dyslipidemia-associated alterations in B cell subpopulations frequency and phenotype during experimental atherosclerosis.
abstract: Cardiovascular diseases are the most common cause of death in the world, atherosclerosis being its main underlying disease. Information about the role of B cells during atherosclerotic process is scarce, but both proatherogenic and atheroprotective properties have been described in the immunopathology of this disease. Frequency and phenotype of B cell subpopulations were studied in wild type and apolipoprotein-E-deficient (apoE (-/-) ) mice fed or not with high-fat diet (HFD), by flow cytometry. Here, we provide the information about the materials, methods, analysis and additional information related to our study published in Atherosclerosis (DOI: 10.1016/j.atherosclerosis.2015.12.022, article reference: ATH14410) [1]. The data contained in this article shows and supports that mice with advanced atherosclerosis have a variety of alterations in frequency and phenotype of B cell subsets, most of which associated with dyslipidemia.
authors.affiliation: Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia.
authors.forename: Héctor
authors.initials: H
authors.lastname: Rincón-Arévalo
authors.affiliation: Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia.
authors.forename: Diana
authors.initials: D
authors.lastname: Castaño
authors.affiliation: Grupo Inmunomodulación, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia.
authors.forename: Janny
authors.initials: J
authors.lastname: Villa-Pulgarín
authors.affiliation: Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia; Unidad de Citometría, Facultad de Medicina, Sede de Investigación Universitaria, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia.
authors.forename: Mauricio
authors.initials: M
authors.lastname: Rojas
authors.affiliation: Grupo de Inmunología Celular e Inmunogenética, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia.
authors.forename: Gloria
authors.initials: G
authors.lastname: Vásquez
authors.affiliation: Sección de Dermatología, Departamento de Medicina Interna, Facultad de Medicina, Universidad de Antioquia. Laboratorio Clínico VID, Obra de la Congregación Mariana, Medellín, Colombia.
authors.forename: Luis A
authors.initials: LA
authors.lastname: Correa
authors.affiliation: Grupo Inmunomodulación, Instituto de Investigaciones Médicas, Facultad de Medicina, Universidad de Antioquia UdeA, Calle 70-52-21, Medellín, Colombia.
authors.forename: José R
authors.initials: JR
authors.lastname: Ramírez-Pineda
authors.affiliation: Grupo de Ciencias Básicas, Universidad CES, Medellín, Colombia.
authors.forename: Lina M
authors.initials: LM
authors.lastname: Yassin
keywords: Apolipoprotein E; Atherosclerosis; B cells; Cholesterol; Dyslipidemia; FBS, Fetal Bovine Serum; HFD, high fat diet; MFI, Mean fluorescence intensity; PBS, phosphate buffered saline; SLD, standard lab diet; apoE−/−, apolipoprotein-E-deficient