title: Sinapic Acid and Its Derivatives as Medicine in Oxidative Stress-Induced Diseases and Aging.
abstract: Sinapic acid (3,5-dimethoxy-4-hydroxycinnamic acid) is an orally bioavailable phytochemical, extensively found in spices, citrus and berry fruits, vegetables, cereals, and oilseed crops and is known to exhibit antioxidant, anti-inflammatory, anticancer, antimutagenic, antiglycemic, neuroprotective, and antibacterial activities. The literature reveals that sinapic acid is a bioactive phenolic acid and has the potential to attenuate various chemically induced toxicities. This minireview is an effort to summarize the available literature about pharmacokinetic, therapeutic, and protective potential of this versatile molecule in health related areas.
authors.affiliation: Key Laboratory of Biorheological Science and Technology, Ministry of Education, Bioengineering College, Chongqing University, Chongqing 400030, China.
authors.forename: Chunye
authors.initials: C
authors.lastname: Chen
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D003373:Coumaric Acids / Q000737:chemistry / Q000378:metabolism / Q000494:pharmacology*; D005609:Free Radicals / Q000737:chemistry; D006801:Humans; D008568:Memory / Q000187:drug effects; D018696:Neuroprotective Agents / Q000737:chemistry / Q000494:pharmacology; D018384:Oxidative Stress / Q000187:drug effects*; D014675:Vegetables / Q000737:chemistry / Q000378:metabolism
chemical_list: D000975:Antioxidants; D003373:Coumaric Acids; D005609:Free Radicals; D018696:Neuroprotective Agents; C073734:sinapinic acid