title: Microwave-Assisted Synthesis of Bioactive Six-Membered Heterocycles and Their Fused Analogues.
abstract: This review describes the formation of six-membered heterocyclic compounds and their fused analogues under microwave activation using modern organic transformations including cyclocondensation, cycloaddition, multicomponents and other modular reactions. The review is divided according to the main heterocycle types in order of increasing complexity, starting with heterocyclic systems containing one, two and three heteroatoms and their fused analogues. Recent microwave applications are reviewed, with special focus on the chemistry of bioactive compounds. Selected examples from the 2006 to 2015 literature are discussed.
authors.affiliation: Laboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, Maroc. m.driowya@hotmail.com.
authors.forename: Mohsine
authors.initials: M
authors.lastname: Driowya
authors.affiliation: Laboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, Maroc. aziza.saber@ymail.com.
authors.forename: Aziza
authors.initials: A
authors.lastname: Saber
authors.affiliation: Laboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, Maroc. marzaghamid@gmail.com.
authors.forename: Hamid
authors.initials: H
authors.lastname: Marzag
authors.affiliation: Institut de Chimie de Nice, ICN UMR UNS CNRS 7272, Université Nice-Sophia Antipolis-Université Côte d'Azur, Parc Valrose, 06108 Nice Cedex 2, France. luc.demange@unice.fr.|Department of Chemistry, Université Paris Descartes, Sorbonne Paris Cité, UFR des Sciences Pharmaceutiques, 4 avenue de l'Observatoire &amp; UFR Biomédicale des Saints Pères, 45 rue des Saints Pères, Paris Fr-75006, France. luc.demange@unice.fr.
authors.forename: Luc
authors.initials: L
authors.lastname: Demange
authors.affiliation: Institut de Chimie de Nice, ICN UMR UNS CNRS 7272, Université Nice-Sophia Antipolis-Université Côte d'Azur, Parc Valrose, 06108 Nice Cedex 2, France. rachid.benhida@unice.fr.
authors.forename: Rachid
authors.initials: R
authors.lastname: Benhida
authors.affiliation: Laboratoire de Chimie des Plantes et de Synthèse Organique et Bioorganique, URAC23, Faculté des Sciences, Université Mohammed V, B.P. 1014 Rabat, Maroc. kbougrin@yahoo.fr.
authors.forename: Khalid
authors.initials: K
authors.lastname: Bougrin
mesh_terms: D020650:Combinatorial Chemistry Techniques; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D008872:Microwaves; D009930:Organic Chemicals / Q000138:chemical synthesis* / Q000737:chemistry; D013237:Stereoisomerism
chemical_list: D006571:Heterocyclic Compounds; D009930:Organic Chemicals
keywords: bioactive molecules; cycloaddition; cyclocondensation; microwave irradiation; multicomponent reactions