title: Daily Rhythms in Mosquitoes and Their Consequences for Malaria Transmission.
abstract: The 24-h day involves cycles in environmental factors that impact organismal fitness. This is thought to select for organisms to regulate their temporal biology accordingly, through circadian and diel rhythms. In addition to rhythms in abiotic factors (such as light and temperature), biotic factors, including ecological interactions, also follow daily cycles. How daily rhythms shape, and are shaped by, interactions between organisms is poorly understood. Here, we review an emerging area, namely the causes and consequences of daily rhythms in the interactions between vectors, their hosts and the parasites they transmit. We focus on mosquitoes, malaria parasites and vertebrate hosts, because this system offers the opportunity to integrate from genetic and molecular mechanisms to population dynamics and because disrupting rhythms offers a novel avenue for disease control.
authors.affiliation: Centre for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh EH9 3FL, UK. Samuel.Rund@ed.ac.uk.
authors.forename: Samuel S C
authors.initials: SS
authors.lastname: Rund
authors.affiliation: Institutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK. Aidan.Odonnell@ed.ac.uk.
authors.forename: Aidan J
authors.initials: AJ
authors.lastname: O'Donnell
authors.affiliation: Invincea Labs LLC, Arlington, VA 22203, USA. jegentile@gmail.com.
authors.forename: James E
authors.initials: JE
authors.lastname: Gentile
authors.affiliation: Institutes of Evolutionary Biology, and Immunology and Infection Research, University of Edinburgh, Edinburgh EH9 3FL, UK. Sarah.Reece@ed.ac.uk.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Reece
keywords: Anopheles; Plasmodium; chronobiology; circadian; diel; diurnal; nocturnal