title: Improving the reliability of peer-reviewed publications: We are all in it together.
abstract: The current, and welcome, focus on standardization of techniques and transparency of reporting in the biomedical, peer-reviewed literature is commendable. However, that focus has been intermittent as well as lacklustre and so failed to tackle the alarming lack of reliability and reproducibly of biomedical research. Authors have access to numerous recommendations, ranging from simple standards dealing with technical issues to those regulating clinical trials, suggesting that improved reporting guidelines are not the solution. The elemental solution is for editors to require meticulous implementation of their journals' instructions for authors and reviewers and stipulate that no paper is published without a transparent, complete and accurate materials and methods section.
authors.affiliation: Faculty of Medical Science, Postgraduate Medical Institute, Anglia Ruskin University, Chelmsford CM1 1SQ, UK; The Gene Team Ltd., UK.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Bustin
authors.affiliation: The Gene Team Ltd., UK; Institute of Population Health, Faculty of Medical and Human Sciences, University of Manchester, Manchester, UK.
authors.forename: Tania
authors.initials: T
authors.lastname: Nolan
keywords: Biomedicine; Microarrays; Next generation sequencing; Reproducibility; Research; qPCR