title: [A COMPARATIVE STUDY ON TREATMENT OF MID-THORACIC OSTEOPOROTIC VERTEBRAL COMPRESSION FRACTURE USING PERCUTANEOUS KYPHOPLASTY WITH UNILATERAL AND BILATERAL APPROACHES].
abstract: OBJECTIVE
  To compare the effectiveness of percutaneous kyphoplasty (PKP) between by unilateral approach and by bilateral approaches for treating mid-thoracic osteoporotic vertebral compression fracture (OVCF).
  
  
  METHODS
  A prospective randomized controlled study was performed on 22 patients with mid-thoracic OVCF between September 2012 and June 2014. PKP was performed by unilateral approach in 11 cases (group A) and by bilateral approaches in 11 cases (group B). There was no significant difference in gender, age, causes of injury, disease duration, affected segment, preoperative bone mineral density, Cobb angle, compression rate of the anterior verterbral height, and Visual analogue scale (VAS) score between 2 groups (P > 0.05). The operation time, perspective times, hospitalization expenses, the leakage of cement, the sagittal Cobb angle, compression rate of the anterior vertebral height, and VAS scores were compared between 2 groups.
  
  
  RESULTS
  The operation time, perspective times, and hospitalization expenses of group A were significantly less than those of group B (P < 0.05). Twenty-two patients were followed up 13-34 months (mean, 15.3 months). Primary healing of incision was obtained in all patients, and no early complication of cement leakage, hypostatic pneumonia, or deep vein thrombosis occurred. At last follow-up, no new fracture occurred at the adjacent segments. The Cobb angle, compression rate of anterior verterbral height, and VAS score at 1 week and last follow-up were significantly improved when compared with preoperative ones in 2 groups (P < 0.05), but no significant difference was found between at 1 week and at last follow-up (P > 0.05). There was no significant difference in Cobb angle, compression rate of the anterior vertebral height, and VAS score between 2 groups at each time point (P > 0.05).
  
  
  CONCLUSIONS
  PKP by both unilateral approach and bilateral approaches has the same effectiveness, but unilateral approach has shorter operation time, less perspective times, and less hospitalization expenses than bilateral approaches.
authors.forename: Fei
authors.initials: F
authors.lastname: Yin
authors.forename: Zhenzhong
authors.initials: Z
authors.lastname: Sun
authors.forename: Sheng
authors.initials: S
authors.lastname: Song
authors.forename: Xuming
authors.initials: X
authors.lastname: Wei
authors.forename: Xueguang
authors.initials: X
authors.lastname: Liu
authors.forename: Qudong
authors.initials: Q
authors.lastname: Yin
authors.forename: Sanjun
authors.initials: S
authors.lastname: Gu
mesh_terms: D001843:Bone Cements; D015519:Bone Density; D005260:Female; D050815:Fractures, Compression / Q000209:etiology / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty / Q000379:methods*; D008159:Lumbar Vertebrae / Q000293:injuries / Q000601:surgery*; D008875:Middle Aged; D061646:Operative Time; D058866:Osteoporotic Fractures / Q000209:etiology / Q000601:surgery*; D011183:Postoperative Complications; D011446:Prospective Studies; D016103:Spinal Fractures / Q000209:etiology / Q000473:pathology / Q000601:surgery*; D013904:Thoracic Vertebrae / Q000293:injuries / Q000601:surgery*; D016896:Treatment Outcome; D054854:Vertebroplasty; D064232:Visual Analog Scale; D014945:Wound Healing
chemical_list: D001843:Bone Cements