title: Intramolecular Pd-Catalyzed Arylation of 1-Amidosugars: A New Route to N-Glycosyl Quinolin-2-ones.
abstract: The synthesis of N-glycosylated quinolin-2-ones via an intramolecular N-arylation of glycosylamides is reported. The coupling involves the use of only Pd(OAc)2 as the catalyst and nBu4NOAc as the base in 1,4-dioxane. This versatile approach allows the synthesis of various N-glycosylated quinolin-2-ones with exclusive α or β selectivity.
authors.affiliation: BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.
authors.forename: Thi Thanh Huyen
authors.initials: TT
authors.lastname: Luong
authors.affiliation: BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.
authors.forename: Jean-Daniel
authors.initials: JD
authors.lastname: Brion
authors.affiliation: Institut de Chimie des Substances Naturelles ICSN-CNRS , Gif-sur-Yvette, France.
authors.forename: Ewen
authors.initials: E
authors.lastname: Lescop
authors.affiliation: BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.
authors.forename: Mouad
authors.initials: M
authors.lastname: Alami
authors.affiliation: BioCIS, Univ. Paris-Sud, CNRS, University Paris-Saclay , Châtenay-Malabry, France.
authors.forename: Samir
authors.initials: S
authors.lastname: Messaoudi