title: Occult Mediastinal Yolk Sac Tumor Producing α-Fetoprotein Detected by 18F-FDG PET/CT.
abstract: Malignant mediastinal yolk sac tumor (YST), especially adult onset, is rare. Herein, we report a case of occult mediastinal YST with α-fetoprotein production revealed by F-FDG PET/CT in a young adult, in which the intense tracer uptake was demonstrated in the anterior mediastinum. This case indicates F-FDG PET/CT may be a useful tool for detecting the occult primaries of YST.
authors.affiliation: From the *Department of Nuclear Medicine, Peking University First Hospital, Beijing; †Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China; and ‡Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.
authors.forename: Meng
authors.initials: M
authors.lastname: Liu
authors.forename: Guoqian
authors.initials: G
authors.lastname: Chen
authors.forename: Zhanli
authors.initials: Z
authors.lastname: Fu
authors.forename: Ziao
authors.initials: Z
authors.lastname: Li
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
mesh_terms: D000328:Adult; D001692:Biological Transport; D018240:Endodermal Sinus Tumor / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D009382:Neoplasms, Unknown Primary / Q000000981:diagnostic imaging* / Q000378:metabolism / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography; D000509:alpha-Fetoproteins / Q000096:biosynthesis*
chemical_list: D000509:alpha-Fetoproteins; D019788:Fluorodeoxyglucose F18