title: Hydrogen sulphide in cardiovascular system: A cascade from interaction between sulphur atoms and signalling molecules.
abstract: As a gasotransmitter, hydrogen sulphide exerts its extensive physiological and pathophysiological effects in mammals. The interaction between sulphur atoms and signalling molecules forms a cascade that modulates cellular functions and homeostasis. In this review, we focus on the signalling mechanism underlying the effect of hydrogen sulphide in the cardiovascular system and metabolism as well as the biological relevance to human diseases.
authors.affiliation: Research Center on Aging and Medicine, Fudan University, Shanghai Key Laboratory of Bioactive Small Molecules, Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, Shanghai, China.
authors.forename: Ming-Jie
authors.initials: MJ
authors.lastname: Wang
authors.affiliation: Department of Basic Medicine, College of Medical Instruments and Foodstuff, University of Shanghai for Science and Technology, Shanghai, China.
authors.forename: Wen-Jie
authors.initials: WJ
authors.lastname: Cai
authors.affiliation: Research Center on Aging and Medicine, Fudan University, Shanghai Key Laboratory of Bioactive Small Molecules, Department of Physiology and Pathophysiology, Shanghai Medical College, Fudan University, Shanghai, China. Electronic address: yczhu@shmu.edu.cn.
authors.forename: Yi-Chun
authors.initials: YC
authors.lastname: Zhu
mesh_terms: D002319:Cardiovascular System / Q000378:metabolism*; D006862:Hydrogen Sulfide / Q000378:metabolism*; D015398:Signal Transduction; D013455:Sulfur / Q000378:metabolism*
chemical_list: D013455:Sulfur; D006862:Hydrogen Sulfide
keywords: Atomic biology; Cardiovascular system; Hydrogen sulphide; Metabolism; Signal transduction