title: [Advance in molecular genetic research on primary congenital glaucoma].
abstract: Primary congenital glaucoma (PCG) is one of the major diseases causing blindness in children, but its pathogenesis has remained unclear. Genetic factors play an important role in the pathogenesis of PCG. Molecular genetics of candidate genes such as CYP1B1, MYOC, LTBP2 and FOXC1 has so far been explored, but no disease-causing gene has been identified. Molecular genetic research on PCG including candidate gene screening and research strategies are reviewed here.
authors.affiliation: Zunyi Medical University, Zunyi, Guizhou 563000, China. zdd25@sina.com.
authors.forename: Xiulan
authors.initials: X
authors.lastname: Li
authors.forename: Haotian
authors.initials: H
authors.lastname: Liu
authors.forename: Dingding
authors.initials: D
authors.lastname: Zhang
mesh_terms: D000818:Animals; D004252:DNA Mutational Analysis; D005820:Genetic Testing; D005901:Glaucoma / Q000235:genetics*; D006801:Humans