title: Development of Primary Thyroid Lymphoma during an Ultrasonographic Follow-up of Hashimoto's Thyroiditis: A Report of 9 Cases.
abstract: We herein experienced 9 patients with primary thyroid lymphoma that developed during 3-18 years of ultrasonographic follow-up of Hashimoto's thyroiditis. All nine patients had localized mucosa-associated lymphoid tissue (MALT) lymphoma. Two patients had diffuse type, one had mixed type, and six had nodular type according to the ultrasonographic classification. A clearly enlarging goiter was observed before the diagnosis of lymphoma in 3 patients. An enlarging goiter was not apparent in the remaining 6 patients with nodular type lymphoma, however, the emergence or enlargement of a hypoechoic nodular lesion was observed. Thyroid MALT lymphoma may be diagnosed early by an ultrasonographic follow-up of Hashimoto's thyroiditis.
authors.affiliation: Tajiri Thyroid Clinic, Japan.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Mizokami
authors.forename: Katsuhiko
authors.initials: K
authors.lastname: Hamada
authors.forename: Tetsushi
authors.initials: T
authors.lastname: Maruta
authors.forename: Kiichiro
authors.initials: K
authors.lastname: Higashi
authors.forename: Hiroto
authors.initials: H
authors.lastname: Yamashita
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Noguchi
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Noguchi
authors.forename: Junichi
authors.initials: J
authors.lastname: Tajiri
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005500:Follow-Up Studies; D050031:Hashimoto Disease / Q000150:complications* / Q000000981:diagnostic imaging; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology