title: Pregabalin in the treatment of red scrotum syndrome: a report of two cases.
abstract: Red scrotum syndrome is a poorly understood, chronic dysesthetic erythema primarily involving the anterior scrotum. Previous reports have indicated that red scrotum syndrome is occasionally responsive to oral doxycycline and oral gabapentin. Otherwise, few therapies have proven successful in treating the disorder. We report two cases of red scrotum syndrome responding to oral pregabalin, an anticonvulsant medication commonly used for neuropathic pain. These two cases suggest pregabalin as an effective means for treating red scrotum syndrome and endorse a neuropathic etiology.
authors.affiliation: University of Tennessee College of Medicine, Chattanooga, Tennessee.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Miller
authors.affiliation: Division of Dermatology, Department of Internal Medicine, East Tennessee State University, Johnson City, Tennessee.
authors.forename: Stuart
authors.initials: S
authors.lastname: Leicht
mesh_terms: D004890:Erythema / Q000188:drug therapy*; D006801:Humans; D006930:Hyperalgesia / Q000188:drug therapy*; D008297:Male; D008875:Middle Aged; D000069583:Pregabalin / Q000627:therapeutic use*; D012611:Scrotum / Q000187:drug effects*; D013577:Syndrome
chemical_list: D000069583:Pregabalin
keywords: genital dysesthesia; neuropathic pain; pregabalin; red scrotum syndrome; systemic therapy