title: Male Breast Cancer in India: Series from a Cancer Research Centre.
abstract: Male breast cancer (MBC) is an uncommon malignancy. The scarcity of cases has reduced the focus of research in this area as compared with female breast cancer. The incidence of breast cancer in males is slowly rising and it becomes important to study the biology of this uncommon illness. Aim of the present work was to study the clinico-pathological behaviour of male breast cancer at a cancer research institute in India. 18 cases of MBC were identified out of 1752 cases of breast cancer registered during a 10 year period. Clinical parameters and histopathological data were analysed. MBC comprised of 1.03 % of total breast cancer cases. Median age of presentation was 60 years. Most of the patients presented to us in advanced stage. Aggressive pattern of disease was recognised with high node positivity, more perineural spread and lymphovascular invasion. Most of the cases were positive for hormone receptors. Breast cancer is seen at a relatively early age in Indian males. Disease is aggressive in nature with high hormone receptor positivity.
authors.affiliation: Department of Medical Oncology, Dharamshila Hospital & Research Centre, Vasundhara Enclave, New Delhi, 110096 India ; 79, Sector 12, Dwarka, New Delhi, 110078 India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Sundriyal
authors.affiliation: Department of Pathology, Dharamshila Hospital & Research Centre, Vasundhara Enclave, New Delhi, 110096 India.
authors.forename: Sumedha
authors.initials: S
authors.lastname: Kotwal
authors.affiliation: Department of Pathology, Dharamshila Hospital & Research Centre, Vasundhara Enclave, New Delhi, 110096 India.
authors.forename: Ramesh
authors.initials: R
authors.lastname: Dawar
authors.affiliation: Department of Medical Oncology, Dharamshila Hospital & Research Centre, Vasundhara Enclave, New Delhi, 110096 India.
authors.forename: K M
authors.initials: KM
authors.lastname: Parthasarathy
keywords: Cinico-pathological characteristics; Estrogen receptor/Progesterone receptor; Invasive ductal carcinoma; Male breast cancer