title: Application of Inverse Liquid Chromatography for Surface Characterization of Biomaterials.
abstract: In the present study, a novel approach for surface characterization of ceramic biomaterials is proposed. Two ceramic biomaterials-hydroxyapatite and β-tricalcium phosphate-were examined by means of inverse liquid chromatography. The Abraham LFER model was applied for physicochemical characteristics of the surface. Different compounds, characterized by different polarity and different donor-acceptor properties of functional group, were used as test solutes. The chromatographic experiments were carried out with two compositions of the mobile phase: pure acetonitrile (MeCN) and the mixture of acetonitrile and water in 80:20 ratio (MeCN/H2O). Thus, the influence of mobile phase on sorption properties of hydroxyapatite and tricalcium phosphate surface was also discussed.
authors.affiliation: Institute of Chemical Technology and Engineering, Poznań University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Adamska
authors.affiliation: Institute of Chemical Technology and Engineering, Poznań University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.
authors.forename: Karol
authors.initials: K
authors.lastname: Kadlec
authors.affiliation: Institute of Chemical Technology and Engineering, Poznań University of Technology, ul. Berdychowo 4, 60-965 Poznań, Poland.
authors.forename: Adam
authors.initials: A
authors.lastname: Voelkel
keywords: Biomaterials; Hydroxyapatite; Inverse liquid chromatography; Linear free energy relationship; Surface characterization