title: Erythrocytes in nanomedicine: an optimal blend of natural and synthetic materials.
abstract: A hybrid approach strategy using synthetic nanoparticles and erythrocytes offers an optimal blend of natural and synthetic materials. The combined advantages of erythrocytes and nanoparticles could serve as an immune-evasive multifunctional platform. This review summarized the research on state-of-the-art and significant advances in erythrocytes for nanomedicine, and presented are their fabrication process, their unique properties and applications. According to its structure, this review mainly focuses on three kinds of erythrocyte-based nanomedicine: whole erythrocytes as carriers, cell membrane coated nanoparticles, and nanoerythrosomes. In addition, some future prospects are also prudentially addressed. We expect rapid success in the advancement of erythrocyte-based nanomedicines, from the bench to the bedside.
authors.affiliation: Department of Oncology, Zhongda Hospital, Medical School, Southeast University, Nanjing, People's Republic of China. zhanghaijunseu@163.com.
authors.forename: Haijun
authors.initials: H
authors.lastname: Zhang
mesh_terms: D000818:Animals; D004337:Drug Carriers / Q000737:chemistry*; D004910:Erythrocyte Membrane / Q000737:chemistry; D004912:Erythrocytes / Q000166:cytology*; D006801:Humans; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D011510:Proteolipids / Q000737:chemistry; D000068936:Theranostic Nanomedicine
chemical_list: D004337:Drug Carriers; D011108:Polymers; D011510:Proteolipids; C020485:proteoliposomes