title: Prevalence of human herpesvirus 8 infection in people living with HIV/AIDS in Pernambuco, Brazil.
abstract: This cross-sectional study aimed to estimate the seroprevalence and risk factors for Human herpesvirus 8 (HHV-8) infection among people living with HIV/AIDS in Recife, Pernambuco, Brazil. A total of 500 individuals were tested for antibodies against HHV-8 using the whole-virus ELISA. The prevalence of anti-HHV-8 was 28.6% and the frequency among 140 men who have sex with men (MSM) was 38.6%. In the univariate model, there were significant associations with male gender, detectable HIV load, travel abroad, bissexual, and homossexual orientation. The first HHV-8 seroepidemiologic study, in northeast Brazil, documents a highly prevalent HHV-8 infection among MSM living with HIV/AIDS. J. Med. Virol. 88:2016-2020, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Virology Division, Laboratory of Immunopathology Keizo Asami (LIKA), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.|Postgraduate Program in Tropical Medicine, Center for Health Sciences (CCS), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
authors.forename: Georgea Gertrudes
authors.initials: GG
authors.lastname: de Oliveira Mendes Cahú
authors.affiliation: Virology Division, Laboratory of Immunopathology Keizo Asami (LIKA), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.|Postgraduate Program in Tropical Medicine, Center for Health Sciences (CCS), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
authors.forename: Viviane Martha Santos
authors.initials: VM
authors.lastname: Morais
authors.affiliation: Virology Division, Laboratory of Immunopathology Keizo Asami (LIKA), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
authors.forename: Thaisa Regina Rocha
authors.initials: TR
authors.lastname: Lopes
authors.affiliation: Virology Division, Laboratory of Immunopathology Keizo Asami (LIKA), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
authors.forename: Dayvson Maurício
authors.initials: DM
authors.lastname: da Silva
authors.affiliation: Departament of Physiology and Pharmacology, Center for Biological Sciences (CCB), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
authors.forename: Tania Regina
authors.initials: TR
authors.lastname: Tozetto-Mendoza
authors.affiliation: Departament of Physiology and Pharmacology, Center for Biological Sciences (CCB), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.
authors.forename: Claudio Sergio
authors.initials: CS
authors.lastname: Pannuti
authors.affiliation: Virology Division, Laboratory of Immunopathology Keizo Asami (LIKA), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.|Postgraduate Program in Tropical Medicine, Center for Health Sciences (CCS), Federal University of Pernambuco (UFPE), Recife, Pernambuco, Brazil.|Laboratory of Virology (LIM52), Institute of Tropical Medicine of São Paulo, University of São Paulo, São Paulo, Brazil.
authors.forename: Maria Rosângela
authors.initials: MR
authors.lastname: Cunha Duarte Coêlho
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology*; D000163:Acquired Immunodeficiency Syndrome / Q000150:complications* / Q000821:virology; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood; D001727:Bisexuality; D001938:Brazil / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D015658:HIV Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology; D015497:HIV-1 / Q000276:immunology / Q000302:isolation & purification; D006566:Herpesviridae Infections / Q000453:epidemiology* / Q000276:immunology / Q000821:virology*; D019288:Herpesvirus 8, Human / Q000276:immunology / Q000302:isolation & purification; D018451:Homosexuality, Male; D006801:Humans; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D014195:Travel; D019562:Viral Load; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral
keywords: Brazil; human herpesvirus 8 (HHV-8); human immunodeficiency virus (HIV); prevalence; sexually transmitted disease