title: Relationship between Serum Ferritin Levels and Dyslipidemia in Korean Adolescents.
abstract: BACKGROUND
  Ferritin is associated with various cardiometabolic risk factors such as dyslipidemia, hypertension, obesity, and insulin resistance in adults. We aimed to study the association between serum ferritin levels and dyslipidemia in adolescents, because dyslipidemia is considered an important modifiable cardiovascular risk factor in the young.
  
  
  METHODS
  We analyzed 1,879 subjects (1,026 boys and 853 girls) from the 2009-2010 Korean National Health and Nutrition Examination Survey IV. Subjects were categorized into quartiles according to their lipid parameters, which were classified according to age and gender. Those in the highest quartile groups for total cholesterol, low-density lipoprotein cholesterol (LDL-C), and triglyceride concentrations were diagnosed as having dyslipidemia. Those in the lowest quartile for high-density lipoprotein cholesterol (HDL-C) values were diagnosed with abnormal levels.
  
  
  RESULTS
  In boys, total cholesterol, LDL-C, and triglyceride concentrations were significantly correlated with serum ferritin levels. In both boys and girls, serum ferritin levels were negatively associated with HDL-C values, even after adjusting for all covariates. Furthermore, there was no significant correlation between serum ferritin levels and total cholesterol, LDL, and triglyceride concentrations in girls.
  
  
  CONCLUSIONS
  Serum ferritin levels were significantly associated with major dyslipidemia parameters, more prominently in boys than in girls, and this association represents a cardiometabolic risk factor.
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Young-Eun
authors.initials: YE
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Do-Hoon
authors.initials: DH
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Hallym University, College of Medicine, Chunchon, Republic of Korea.
authors.forename: Yong-Kyun
authors.initials: YK
authors.lastname: Roh
authors.affiliation: Department of Family Medicine, Catholic University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Sang-Yhun
authors.initials: SY
authors.lastname: Ju
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Yeo-Joon
authors.initials: YJ
authors.lastname: Yoon
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Ga-Eun
authors.initials: GE
authors.lastname: Nam
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Hyo-Yun
authors.initials: HY
authors.lastname: Nam
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Jun-Seok
authors.initials: JS
authors.lastname: Choi
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Jong-Eun
authors.initials: JE
authors.lastname: Lee
authors.affiliation: Department of Family Medicine, Korea University, College of Medicine, Seoul, Republic of Korea.
authors.forename: Jung-Eun
authors.initials: JE
authors.lastname: Sang
authors.affiliation: Department of Biostatistics, Catholic University College of Medicine, Seoul, Republic of Korea.
authors.forename: Kyungdo
authors.initials: K
authors.lastname: Han
authors.affiliation: Department of Biostatistics, Catholic University College of Medicine, Seoul, Republic of Korea.
authors.forename: Yong-Gyu
authors.initials: YG
authors.lastname: Park
mesh_terms: D000293:Adolescent; D002648:Child; D002784:Cholesterol / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood; D008078:Cholesterol, LDL / Q000097:blood; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000097:blood* / Q000145:classification; D005260:Female; D005293:Ferritins / Q000097:blood*; D006801:Humans; D007333:Insulin Resistance; D008297:Male; D009749:Nutrition Surveys; D056910:Republic of Korea; D012307:Risk Factors; D014280:Triglycerides / Q000097:blood
chemical_list: D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D014280:Triglycerides; D005293:Ferritins; D002784:Cholesterol