title: Oxazole: A Promising Building Block for the Development of Potent Antitumor Agents.
abstract: Oxazole derivatives are found to have a variety of biological activities. A large number of studies have revealed their outstanding anticancer activities. Here we review four different types of oxazole derivatives with anticancer potential reported over the last ten years. We focus our discussion on their activity, selectivity in different cancer cell lines, mechanisms of action, and their structural evolution.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhou
authors.forename: Jiang-Qun
authors.initials: JQ
authors.lastname: Cheng
authors.forename: Zhi-Sen
authors.initials: ZS
authors.lastname: Wang
authors.forename: Fei-Hu
authors.initials: FH
authors.lastname: Chen
authors.affiliation: School of Pharmacy, Anhui Medical University, Hefei 230032, China.. xhliuhx@163.com.
authors.forename: Xin-Hua
authors.initials: XH
authors.lastname: Liu
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology*; D015195:Drug Design; D010080:Oxazoles / Q000737:chemistry*
chemical_list: D000970:Antineoplastic Agents; D010080:Oxazoles