title: Electrostatic powder coating: Principles and pharmaceutical applications.
abstract: A majority of pharmaceutical powders are insulating materials that have a tendency to accumulate charge. This phenomenon has contributed to safety hazards and issues during powder handling and processing. However, increased understanding of this occurrence has led to greater understanding and control of processing and product performance. More recently, the charging of pharmaceutical powders has been employed to adopt electrostatic powder coating as a pharmaceutical process. Electrostatic powder coating is a mature technology used in the finishing industry and much of that knowledge applies to its use in pharmaceutical applications. This review will serve to summarize the principles of electrostatic powder coating and highlight some of the research conducted on its use for the preparation of pharmaceutical dosage forms.
authors.affiliation: College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Campus Mail Code A1920, Austin, TX 78712, USA. Electronic address: leena.prasad@utexas.edu.
authors.forename: Leena Kumari
authors.initials: LK
authors.lastname: Prasad
authors.affiliation: College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Campus Mail Code A1920, Austin, TX 78712, USA.
authors.forename: James W
authors.initials: JW
authors.lastname: McGinity
authors.affiliation: College of Pharmacy, The University of Texas at Austin, 2409 University Avenue, Campus Mail Code A1920, Austin, TX 78712, USA.
authors.forename: Robert O
authors.initials: RO
authors.lastname: Williams
mesh_terms: D002626:Chemistry, Pharmaceutical / Q000379:methods; D005079:Excipients / Q000737:chemistry*; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry; D011208:Powders; D055672:Static Electricity; D013678:Technology, Pharmaceutical / Q000379:methods
chemical_list: D005079:Excipients; D004364:Pharmaceutical Preparations; D011208:Powders
keywords: Dry powder coating; Electrostatic powder coating; Electrostatic powder deposition; Oral film; Powder charging