title: Contribution of tactile dysfunction to manual motor dysfunction in type II diabetes.
abstract: Changes in sensory and motor functions of the hand in type II diabetes (T2D) patients have been reported; there is speculation that these changes are driven by tactile dysfunction. The purpose of this study was to evaluate the effects of tactile feedback on manual function in T2D patients.
  
  
  
  T2D patients and healthy controls underwent median nerve blocks at the wrist and elbow. All participants underwent traditional timed motor evaluations, force dynamometry, laboratory-based kinetic evaluations, and sensory evaluation.
  
  
  
  Tactile sensation in the T2D group at baseline was found to be equivalent to tactile function of the control group after median nerve block. Traditional timed evaluation results were negatively impacted by anesthesia, but more sensitive kinetic measures were not impacted.
  
  
  
  These data suggest that mechanisms outside of tactile dysfunction play a significant role in motor dysfunction in T2D. Muscle Nerve 54: 895-902, 2016.
authors.affiliation: Department of Health and Human Performance, University of Houston, 3875 Holman Street, Garrison 104N, Houston, Texas, 77204, USA.|Center for Neuromotor and Biomechanics Research, University of Houston, Houston, Texas, USA.
authors.forename: Nereyda
authors.initials: N
authors.lastname: Ochoa
authors.affiliation: Hand and Upper Extremity Surgery, Shriners Hospitals for Children, Houston, Houston, Texas, USA.
authors.forename: Gloria R
authors.initials: GR
authors.lastname: Gogola
authors.affiliation: Department of Health and Human Performance, University of Houston, 3875 Holman Street, Garrison 104N, Houston, Texas, 77204, USA. sgorniak@uh.edu.|Center for Neuromotor and Biomechanics Research, University of Houston, Houston, Texas, USA. sgorniak@uh.edu.|Texas Obesity Research Center, University of Houston, Houston, Texas, USA. sgorniak@uh.edu.
authors.forename: Stacey L
authors.initials: SL
authors.lastname: Gorniak
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D000779:Anesthetics, Local / Q000494:pharmacology; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000150:complications*; D005260:Female; D018737:Hand Strength / Q000502:physiology; D006801:Humans; D007699:Kinesthesis / Q000502:physiology; D008012:Lidocaine / Q000494:pharmacology; D008297:Male; D008475:Median Nerve / Q000187:drug effects / Q000503:physiopathology; D008875:Middle Aged; D011434:Proprioception / Q000187:drug effects / Q000502:physiology; D011596:Psychomotor Disorders / Q000175:diagnosis / Q000209:etiology*; D012678:Sensation Disorders / Q000209:etiology*; D012720:Severity of Illness Index; D014110:Touch / Q000502:physiology*
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine
keywords: finger; hand; motor; sensory function; tactile; type II diabetes