title: Afebrile Multi-valve Infective Endocarditis Caused by Lactococcus garvieae: A Case Report and Literature Review.
abstract: Lactococcus garvieae is considered to be a rare pathogen with low virulence in humans. We herein experienced an unusual case of multi-valve infective endocarditis caused by L. garvieae in an elderly woman who had undergone bioprosthetic mitral valve replacement due to severe mitral stenosis with rheumatic etiology. The patient was successfully treated with cardiac surgery after teicoplanin antimicrobial therapy failure followed by ceftriaxone treatment. L. garvieae was confirmed as the pathogen through 16S rRNA sequencing. To the best of our knowledge, this is the first case to indicate an effective treatment for infective endocarditis caused by L. garvieae in the Republic of Korea.
authors.affiliation: Division of Infectious Diseases, Department of Internal Medicine, University of Ulsan College of Medicine, Korea.
authors.forename: Yooseok
authors.initials: Y
authors.lastname: Suh
authors.forename: Min
authors.initials: M
authors.lastname: Ja Kim
authors.forename: Jae
authors.initials: J
authors.lastname: Seung Jung
authors.forename: Yong
authors.initials: Y
authors.lastname: Pil Chong
authors.forename: Chul
authors.initials: C
authors.lastname: Hwan Kim
authors.forename: Youngjin
authors.initials: Y
authors.lastname: Kang
authors.forename: Jang
authors.initials: J
authors.lastname: Wook Sohn
authors.forename: Young
authors.initials: Y
authors.lastname: Kyung Yoon
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D004697:Endocarditis, Bacterial / Q000209:etiology / Q000382:microbiology*; D005260:Female; D016908:Gram-Positive Bacterial Infections / Q000209:etiology / Q000382:microbiology*; D006350:Heart Valve Prosthesis / Q000009:adverse effects; D006801:Humans; D017045:Lactococcus; D008946:Mitral Valve Stenosis / Q000601:surgery; D056910:Republic of Korea; D017334:Teicoplanin / Q000627:therapeutic use
chemical_list: D000900:Anti-Bacterial Agents; D017334:Teicoplanin