title: Quantitative online sheath-flow surface enhanced Raman spectroscopy detection for liquid chromatography.
abstract: Sheath-flow surface-enhanced Raman spectroscopy (SERS) was used for online detection and quantification of small molecules separated by liquid chromatography. A mixture of model metabolites (thiamine, folic acid, and riboflavin) was separated and characterized by UV-Vis and SERS detectors connected in series. Acetonitrile in the mobile phase provided an internal standard enabling quantitative detection across SERS experiments.
authors.affiliation: Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN 46556, USA. Schultz.41@nd.edu.
authors.forename: Anh
authors.initials: A
authors.lastname: Nguyen
authors.forename: Zachary D
authors.initials: ZD
authors.lastname: Schultz