title: Can propolis and caffeic acid phenethyl ester be promising agents against cyclophosphamide toxicity?
abstract: Propolis is a mixture having hundreds of polyphenols including caffeic acid phenethyl ester (CAPE). They have been using in several medical conditions/diseases in both in vitro and in vivo experimental setup. Cyclophosphamide (CP) has been used to treat a broad of malignancies including Hodgkin's and non-Hodgkin's lymphoma, Burkitt's lymphoma, chronic lymphocytic leukemia, Ewing's sarcoma, breast cancer, testicular cancer, etc. It may cause several side effects after treatment. In this mini review, the protective effects of propolis and CAPE were compared each other in terms of effectiveness against CP-induced injuries.
authors.affiliation: Department of Medical Biology, Turgut Ozal University Medical Faculty, Ankara, Turkey.
authors.forename: Sumeyya
authors.initials: S
authors.lastname: Akyol
authors.affiliation: Department of Medical Biochemistry, Faculty of Medicine, Turgut Ozal University, Ankara, Turkey.
authors.forename: Mehmet Akif
authors.initials: MA
authors.lastname: Gulec
authors.affiliation: Department of Biochemistry Laboratory, Corum Training and Research Hospital, Corum, Turkey.
authors.forename: Haci Kemal
authors.initials: HK
authors.lastname: Erdemli
authors.affiliation: Department of Medical Biochemistry, Hacettepe University Medical Faculty, Ankara, Turkey.
authors.forename: Omer
authors.initials: O
authors.lastname: Akyol
keywords: Caffeic acid phenethyl ester; cyclophosphamide; propolis