title: Prospective evaluation of skin and nipple-areola sensation and patient satisfaction after nipple-sparing mastectomy.
abstract: BACKGROUND
  Sensation and quality of life (QOL) before and after nipple sparing mastectomy (NSM) are poorly understood.
  
  
  METHODS
  Women electing mastectomy with immediate reconstruction and eligible for NSM were prospectively enrolled in a sensation and satisfaction/QOL study. Women self-selected skin-sparing mastectomy (SSM) or NSM. Skin sensation testing using Semmes Weinstein monofilaments and patient satisfaction/QOL surveys were administered preoperatively and at 1 year postoperatively.
  
  
  RESULTS
  53 patients were enrolled (n = 38, 72% NSM and n = 15, 28% SSM). Both groups had significant reduction in postoperative skin sensation. For NSM, measurable NAC sensation was preserved in both NAC for 26% of patients and in one NAC for 68%. QOL and satisfaction was similar between groups. Neither group was satisfied with sexual arousal with breast or nipple stimulation after surgery.
  
  
  CONCLUSIONS
  Patients undergoing SSM and NSM have considerable loss in skin and NAC sensation following surgery. Satisfaction and QOL did not differ between groups. J. Surg. Oncol. 2016;114:11-16. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Comprehensive Breast Program, Moffitt Cancer Center, Tampa, Florida.
authors.forename: Lesly A
authors.initials: LA
authors.lastname: Dossett
authors.affiliation: Comprehensive Breast Program, Moffitt Cancer Center, Tampa, Florida.
authors.forename: Janell
authors.initials: J
authors.lastname: Lowe
authors.affiliation: Comprehensive Breast Program, Moffitt Cancer Center, Tampa, Florida.
authors.forename: Weihong
authors.initials: W
authors.lastname: Sun
authors.affiliation: Comprehensive Breast Program, Moffitt Cancer Center, Tampa, Florida.
authors.forename: M C
authors.initials: MC
authors.lastname: Lee
authors.affiliation: Comprehensive Breast Program, Moffitt Cancer Center, Tampa, Florida.|Division of Plastic Surgery, Department of Surgery, University of South Florida, Tampa, Florida.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Smith
authors.affiliation: Department of Health Outcomes and Behavior, Moffitt Cancer Center, Tampa, Florida.
authors.forename: Paul B
authors.initials: PB
authors.lastname: Jacobsen
authors.affiliation: Comprehensive Breast Program, Moffitt Cancer Center, Tampa, Florida.
authors.forename: Christine
authors.initials: C
authors.lastname: Laronga
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001828:Body Image; D001943:Breast Neoplasms / Q000601:surgery; D005260:Female; D006801:Humans; D015414:Mastectomy, Subcutaneous; D008875:Middle Aged; D009558:Nipples / Q000502:physiology*; D017063:Outcome Assessment, Health Care; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D011446:Prospective Studies; D011788:Quality of Life; D012879:Skin Physiological Phenomena; D014110:Touch; D055815:Young Adult
keywords: breast cancer; nipple sensation; nipple-sparing mastectomy; outcomes; quality of life