title: Disseminated Panton-Valentine Leukocidin-Positive Staphylococcus aureus infection in a child.
abstract: Panton-Valentine leukocidin (PVL) is an exotoxin that is produced by many strains of Staphylococcus aureus, and an important virulence factor. A PVL-positive S. aureus infection leads to rapid and severe infections of soft tissue and necrotizing pneumonia in healthy adolescents, and has a high mortality. This case report included a 12-year-old male patient who admitted for fever, respiratory distress and hip pain and was identified with necrotizing pneumonia with septic pulmonary embolism, psoas abscess, cellulitis and osteomyelitis. The PVL positive methicillin-sensitive S. aureus (MSSA) was isolated in the patient blood culture.
authors.affiliation: Department of Pediatric Infectious Diseases, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey. drarzukarli@yahoo.com.
authors.forename: Arzu
authors.initials: A
authors.lastname: Karli
authors.affiliation: Department of Clinical Microbiology, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Keramettin
authors.initials: K
authors.lastname: Yanik
authors.affiliation: Department of Pediatric Intensive Care Unit, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Muhammet S
authors.initials: MS
authors.lastname: Paksu
authors.affiliation: Department of Pediatric Infectious Diseases, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Gulnar
authors.initials: G
authors.lastname: Sensoy
authors.affiliation: Department of Pediatric Intensive Care Unit, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Aykanat
authors.affiliation: Department of Pediatric Intensive Care Unit, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Nazik
authors.initials: N
authors.lastname: Yener
authors.affiliation: Department of Pediatric Infectious Diseases, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Nursen
authors.initials: N
authors.lastname: Belet
authors.affiliation: Department of Radiology, Tıp Fakültesi, Ondokuz Mayıs Üniversitesi (OMÜ), Atakum/Samsun, 55270, Turkey.
authors.forename: Meltem
authors.initials: M
authors.lastname: Ceyhan
mesh_terms: D001427:Bacterial Toxins / Q000032:analysis*; D002648:Child; D017714:Community-Acquired Infections; D005098:Exotoxins / Q000032:analysis*; D006801:Humans; D007956:Leukocidins / Q000032:analysis*; D008297:Male; D013203:Staphylococcal Infections / Q000175:diagnosis*; D013211:Staphylococcus aureus
chemical_list: D001427:Bacterial Toxins; D005098:Exotoxins; D007956:Leukocidins; C078284:Panton-Valentine leukocidin
keywords: Necrotizing pneumonia; Panton-Valentine leukocidin; Sepsis; Staphylococcus aureus