title: Scope of Hydrolysable Tannins as Possible Antimicrobial Agent.
abstract: Hydrolysable tannins (HTs) are secondary metabolites from plants, which are roughly classified into gallotannins and ellagitannins having gallic acid and ellagic acid residues respectively attached to the hydroxyl group of glucose by ester linkage. The presence of hexahydroxydiphenoyl and nonahydroxyterphenoyl moieties is considered to render antimicrobial property to HTs. HTs also show considerable synergy with antibiotics. Nevertheless, they have low pharmacokinetic property. The present review presents the scope of HTs as future antimicrobial agent. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Department of Pharmaceutical Technology, Anna University BIT Campus, Tiruchirappalli, 620 024, Tamilnadu, India.
authors.forename: Sanmuga Priya
authors.initials: SP
authors.lastname: Ekambaram
authors.affiliation: Department of Pharmaceutical Technology, Anna University BIT Campus, Tiruchirappalli, 620 024, Tamilnadu, India.
authors.forename: Senthamil Selvan
authors.initials: SS
authors.lastname: Perumal
authors.affiliation: Department of Pharmaceutical Technology, Anna University BIT Campus, Tiruchirappalli, 620 024, Tamilnadu, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Balakrishnan
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001682:Biological Availability; D004357:Drug Synergism; D047348:Hydrolyzable Tannins / Q000493:pharmacokinetics / Q000494:pharmacology*; D008826:Microbial Sensitivity Tests
chemical_list: D000890:Anti-Infective Agents; D047348:Hydrolyzable Tannins
keywords: ETs; antimicrobials; gallotannins; hydrolysable tannins; synergy