title: [Chronic cerebral circulatory insufficiency: A clinical case report].
abstract: Chronic cerebral circulatory insufficiency (CCCI) is a result of cerebral microangiopathy, most commonly due to uncontrolled hypertension. In this case, the brain is affected due to recurrent silent infarcts and/or microbleedings without clinical manifestations of stroke and chronic brain ischemia. Progressive cognitive impairments with a preponderance of inadequate attention and lower rates of cognitive performance, with impaired planning and control abilities in relative preservation of memory serve as the main manifestation of chronic progressive non-stroke vascular lesion in the brain. The above impairments are generally associated with emotional changes as affective lability and depression. The paper gives an account of a characteristic clinical case of CCCI, analyzes the mechanisms for the development of neurological symptoms, and sets forth current approaches to managing these patients.
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Zakharov
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: N V
authors.initials: NV
authors.lastname: Vakhnina
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: D O
authors.initials: DO
authors.lastname: Gromova
authors.affiliation: I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Tarapovskaya
mesh_terms: D001921:Brain / Q000098:blood supply*; D002545:Brain Ischemia / Q000175:diagnosis / Q000209:etiology; D002319:Cardiovascular System; D006801:Humans; D006973:Hypertension / Q000150:complications; D020521:Stroke