title: A rare adverse reaction to ethambutol: drug-induced haemolytic anaemia.
abstract: Anti-tuberculosis drugs seldom cause serious haematological side effects. However, among these drugs, isoniazid and rifampicin, especially when administered intermittently, may very rarely be linked to acute autoimmune haemolytic anaemia. Ethambutol (EMB) can cause dose-related retrobulbar neuritis. In this paper, we present the first reported case of acute fatal autoimmune haemolytic anaemia due to EMB.
authors.affiliation: Respiratory Diseases Unit, General Hospital, Sestri Levante, Genoa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Nicolini
authors.affiliation: Respiratory Diseases Unit, General Hospital, Sestri Levante, Genoa, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Perazzo
authors.affiliation: Respiratory Diseases Unit, General Hospital, Sestri Levante, Genoa, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Gatto
authors.affiliation: Respiratory Diseases Unit, General Hospital, Sestri Levante, Genoa, Italy.
authors.forename: I M G
authors.initials: IM
authors.lastname: Piroddi
authors.affiliation: Hygiene and Health Medicine Unit, General Hospital, Sestri Levante, Genoa, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Barlascini
authors.affiliation: Department of Allergy and Respiratory Diseases, General Hospital, Sestri Levante, Genoa, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Karamichali
authors.affiliation: Immunohaematology Service, Istituto Di Ricovero e Cura a Carattere Scientifico Azienda Ospedaliera Universitaria San Martino Istituto Scientifico Tumori, Genoa, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Strada
mesh_terms: D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D000995:Antitubercular Agents / Q000009:adverse effects*; D004977:Ethambutol / Q000009:adverse effects*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D012307:Risk Factors; D012830:Silicotuberculosis / Q000188:drug therapy*
chemical_list: D000995:Antitubercular Agents; D004977:Ethambutol