title: Cancer cell-targeted two-photon fluorescence probe for the real-time ratiometric imaging of DNA damage.
abstract: Real-time imaging of DNA damage in cancer cells could provide valuable information on the formation and development of cancer. Herein, a two-photon fluorescence probe was discovered. Through sequential ICT processes, it allows successful in vivo visualization of DNA damage in cancer cells by one/two-photon microscopic imaging or by the unaided eye and a hand-held ultraviolet lamp.
authors.affiliation: Henan Key Laboratory of Green Chemical Media and Reactions, Ministry of Education, Key Laboratory of Green Chemical Media and Reactions, Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals, School of Chemistry and Chemical Engineering Institution, Henan Normal University, 453007 Xinxiang, China. zhh1106@htu.edu.cn zhanghua1106@163.com ghm@htu.edu.cn.
authors.forename: Hua
authors.initials: H
authors.lastname: Zhang
authors.forename: Kui
authors.initials: K
authors.lastname: Wang
authors.forename: Xiaopeng
authors.initials: X
authors.lastname: Xuan
authors.forename: Qingzhang
authors.initials: Q
authors.lastname: Lv
authors.forename: Yamin
authors.initials: Y
authors.lastname: Nie
authors.forename: Haiming
authors.initials: H
authors.lastname: Guo
mesh_terms: D000818:Animals; D002460:Cell Line; D003412:Cricetulus; D004249:DNA Damage; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D009369:Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D017785:Photons; D013050:Spectrometry, Fluorescence; D013997:Time Factors; D014466:Ultraviolet Rays
chemical_list: D005456:Fluorescent Dyes