title: Diabetes Mellitus and Risk of Bronchopleural Fistula After Pulmonary Resections: A Meta-Analysis.
abstract: We conducted this meta-analysis to evaluate the association between diabetes mellitus and the risk of bronchopleural fistula in patients undergoing pulmonary resection. The PubMed and EMBASE databases were searched, and 15 retrospective observational studies were included. The pooled analysis showed that diabetes mellitus was significantly associated with the formation of bronchopleural fistula after pulmonary resection (odds ratio = 1.97; 95% confidence interval = 1.39 to 2.80; p < 0.001). This association remained statistically prominent in the subgroups classified by statistical analysis, diagnoses and operative modes and in Asian patients. Therefore, diabetes mellitus can be an independent risk factor for bronchopleural fistula after pulmonary resection.
authors.affiliation: Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Shuang-Jiang
authors.initials: SJ
authors.lastname: Li
authors.affiliation: Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Fan
authors.affiliation: Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Jian
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Lung Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Yu-Tao
authors.initials: YT
authors.lastname: Ren
authors.affiliation: Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Shen
authors.affiliation: Department of Thoracic Surgery, West China Hospital, Sichuan University, Chengdu, China. Electronic address: guowei_che@yahoo.com.
authors.forename: Guo-Wei
authors.initials: GW
authors.lastname: Che
mesh_terms: D001983:Bronchial Fistula / Q000209:etiology*; D003920:Diabetes Mellitus; D005402:Fistula / Q000209:etiology; D006801:Humans; D010995:Pleural Diseases / Q000209:etiology*; D011013:Pneumonectomy / Q000009:adverse effects*; D011183:Postoperative Complications; D012307:Risk Factors