title: Care System Versus Transmitted Light Wavefront Pattern of Contact Lenses.
abstract: OBJECTIVE
  This article compares the optical performance of soft contact lenses (CLs) treated with multipurpose or hydrogen peroxide care systems.
  
  
  METHODS
  The investigated care systems were (1) 3% hydrogen peroxide solution Oxysept (Abbot Medical Optics, Abbott Park, IL) and (2) multipurpose solution Regard (Vita Research, Ariccia, Italy). Three types of silicone hydrogel CLs were studied (comfilcon A, lotrafilcon B, and balafilcon A), unworn and exposed for 30 times to the solutions, which were replaced every 8 hr. The optical performance of the CLs was evaluated through the on-eye transmitted light wavefront patterns by considering new CLs as references. The surface morphology of the CLs was investigated by scanning electron microscopy.
  
  
  RESULTS
  Statistically significant modifications in the range 0.1 to 0.3 μm of Zernicke coefficients and modifications of the root mean square of the wavefront aberration function were found for CLs treated with multipurpose solution, in agreement with the observed modifications of the surface morphology. Statistically significant changes were also found after exposure to the hydrogen peroxide solution, but the variation of the Zernicke coefficients was found lower than 0.1 μm, thus being negligible in CL optical performances.
  
  
  CONCLUSIONS
  In addition to disinfection ability and ocular surface reactions, CL care systems are different in solution-related CL optical performance. Multipurpose solutions may affect the CL surface morphology with significant modifications of the transmitted light wavefront pattern.
authors.affiliation: Materials Science Department (S.C., A.B., F.C., L.F., M.A., S.T.), University of Milano Bicocca, Milan, Italy; COMiB (A.B., M.A., S.T.), University of Milano Bicocca, Milan, Italy; National Interuniversity Consortium of Materials Science and Technology INSTM (F.C.), Florence, Italy; and DeFENS, Department of Food, Environmental and Nutritional Sciences (S.F.), Packaging Division, University of Milan, Milan, Italy.
authors.forename: Stefano
authors.initials: S
authors.lastname: Chiericati
authors.forename: Alessandro
authors.initials: A
authors.lastname: Borghesi
authors.forename: Federica
authors.initials: F
authors.lastname: Cozza
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Ferraro
authors.forename: Maurizio
authors.initials: M
authors.lastname: Acciarri
authors.forename: Stefano
authors.initials: S
authors.lastname: Farris
authors.forename: Silvia
authors.initials: S
authors.lastname: Tavazzi
mesh_terms: D018639:Contact Lens Solutions / Q000737:chemistry*; D003261:Contact Lenses; D004866:Equipment Contamination / Q000517:prevention & control; D006801:Humans; D008422:Materials Testing; D008855:Microscopy, Electron, Scanning; D016249:Optical Storage Devices
chemical_list: D018639:Contact Lens Solutions