title: Eight-year experience of using HTA in drug reimbursement: South Korea.
abstract: This study describes the process and results of drug reimbursement decision-making in South Korea and evaluates its performance from the perspectives of the various stakeholders involved. Data were retrieved from the evaluation report posted on the Health Insurance Review and Assessment Service (HIRA) website. As of 2014, 253 new drugs had been submitted to the HIRA for appraisal. Of these, 175 (69.2%) were recommended in favor of listing and 78 (30.8%) were rejected. Furthermore, 68 of these drugs were deemed clinically improved relative to existing drugs. For those drugs that did not demonstrate clinical superiority (which was most of them), a simple price comparison to the existing drug was utilized as a gate toward listing. On top of the base-line analysis, 104 stakeholders from the industry, academia, public office, and civic society responded to a questionnaire designed to obtain their opinions on the South Korean positive list system (PLS). Stakeholders agreed that the consistency of reimbursement decision-making has improved since 2007, while accessibility to new drugs has apparently decreased. Respondents also indicated a preference toward improved public access to decision-making information. This examination of reimbursement decisions in South Korea will illuminate critical issues for countries that are considering the introduction of similar policies.
authors.affiliation: School of Pharmacy, Gyeongsang National University, Jinju, South Korea; Institute of Pharmacy, Gyeongsang National University, Jinju, South Korea. Electronic address: eybae@gnu.ac.kr.
authors.forename: Eun-Young
authors.initials: EY
authors.lastname: Bae
authors.affiliation: Graduate School of Public Health, Seoul National University, Seoul, South Korea.
authors.forename: Ji-Min
authors.initials: JM
authors.lastname: Hong
authors.affiliation: School of Techno-Sciences, Mokwon University, Daejeon, South Korea.
authors.forename: Hye-Young
authors.initials: HY
authors.lastname: Kwon
authors.affiliation: Graduate School of Public Health, Seoul National University, Seoul, South Korea.
authors.forename: Suhyun
authors.initials: S
authors.lastname: Jang
authors.affiliation: Health Insurance Policy Research Institute, National Health Insurance Service, Seoul, South Korea.
authors.forename: Hye-Jae
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Ewha Womans University, Seoul, South Korea.
authors.forename: SeungJin
authors.initials: S
authors.lastname: Bae
authors.affiliation: Graduate School of Public Health, Seoul National University, Seoul, South Korea.
authors.forename: Bong-Min
authors.initials: BM
authors.lastname: Yang
mesh_terms: D003362:Cost-Benefit Analysis; D003657:Decision Making; D016527:Drug Costs; D006291:Health Policy; D006801:Humans; D007349:Insurance, Health, Reimbursement / Q000191:economics*; D009313:National Health Programs / Q000191:economics; D056910:Republic of Korea; D013673:Technology Assessment, Biomedical / Q000379:methods*
keywords: Accountability; Drug reimbursement; Economic evaluation; Health technology assessment; South Korea