title: Australasian Society of Infectious Diseases updated guidelines for the management of Clostridium difficile infection in adults and children in Australia and New Zealand.
abstract: The incidence of Clostridium difficile infection (CDI) continues to rise, whilst treatment remains problematic due to recurrent, refractory and potentially severe nature of disease. The treatment of C. difficile is a challenge for community and hospital-based clinicians. With the advent of an expanding therapeutic arsenal against C. difficile since the last published Australasian guidelines, an update on CDI treatment recommendations for Australasian clinicians was required. On behalf of the Australasian Society of Infectious Diseases, we present the updated guidelines for the management of CDI in adults and children.
authors.affiliation: Infectious Diseases Department, Austin Health, Melbourne, Western Australia.|Infectious Diseases Department, Peter MacCallum Cancer Centre, Melbourne, Western Australia.
authors.forename: J A
authors.initials: JA
authors.lastname: Trubiano
authors.affiliation: Infectious Diseases Department, Alfred Health, Melbourne, Western Australia.|Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Western Australia.|Infection Prevention and Healthcare Epidemiology Unit, Alfred Hospital, Melbourne, Western Australia.
authors.forename: A C
authors.initials: AC
authors.lastname: Cheng
authors.affiliation: Monash Infectious Diseases, Monash Health, Monash University, Melbourne, Western Australia.
authors.forename: T M
authors.initials: TM
authors.lastname: Korman
authors.affiliation: School of Medicine, Deakin University, Geelong, Victoria, Western Australia.|Geelong Centre for Emerging Infectious Diseases, Barwon Health, Geelong, Victoria, Western Australia.
authors.forename: C
authors.initials: C
authors.lastname: Roder
authors.affiliation: Infectious Diseases Department, Princess Margaret Hospital for Children, Queen Elizabeth II Medical Centre, Perth, Western Australia.
authors.forename: A
authors.initials: A
authors.lastname: Campbell
authors.affiliation: Infection Management and Prevention Service, Lady Cilento Children's Hospital and Sullivan Nicolaides Pathology, Brisbane, Queensland.
authors.forename: M L A
authors.initials: ML
authors.lastname: May
authors.affiliation: Infectious Diseases Department, Princess Margaret Hospital for Children, Queen Elizabeth II Medical Centre, Perth, Western Australia.|School of Paediatrics and Child Health, The University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia.|Department of Microbiology, PathWest Laboratory Medicine, Princess Margaret Hospital, Queen Elizabeth II Medical Centre, Perth, Western Australia.
authors.forename: C C
authors.initials: CC
authors.lastname: Blyth
authors.affiliation: Pathology North, NSW Pathology, Wellington South, New Zealand.|Immunology and Infectious Diseases Unit, John Hunter Hospital, Wellington South, New Zealand.|Universities of New England and Newcastle, Newcastle, New South Wales, Australia.
authors.forename: J K
authors.initials: JK
authors.lastname: Ferguson
authors.affiliation: Laboratory Services, Wellington Regional Hospital, Wellington South, New Zealand.
authors.forename: T K
authors.initials: TK
authors.lastname: Blackmore
authors.affiliation: Microbiology and Immunology, School of Pathology and Laboratory Medicine, The University of Western Australia, Queen Elizabeth II Medical Centre, Perth, Western Australia.|Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Western Australia.
authors.forename: T V
authors.initials: TV
authors.lastname: Riley
authors.affiliation: School of Medicine, Deakin University, Geelong, Victoria, Western Australia.|Department of Infectious Disease, Barwon Health, Geelong, Victoria, Western Australia.
authors.forename: E
authors.initials: E
authors.lastname: Athan
mesh_terms: D000328:Adult; D044362:Australasia / Q000453:epidemiology; D001315:Australia / Q000453:epidemiology; D016360:Clostridioides difficile / Q000302:isolation & purification; D003015:Clostridium Infections / Q000175:diagnosis / Q000453:epidemiology* / Q000628:therapy*; D003141:Communicable Diseases / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy; D019468:Disease Management; D006801:Humans; D009520:New Zealand / Q000453:epidemiology; D017410:Practice Guidelines as Topic / Q000592:standards*; D012955:Societies, Medical / Q000592:standards* / Q000639:trends
keywords: Clostridium difficile; faecal microbiota transplant (FMT); fidaxomicin; metronidazole; treatment; vancomycin