title: Symptom management during and after treatment with concurrent chemoradiotherapy for oropharyngeal cancer: A review of the literature and areas for future research.
abstract: Patients with locally advanced oropharyngeal cancer are at risk for poor outcomes due to the multi-modal nature of treatment and the potential for treatment-related toxicity. Although treatment with concurrent chemotherapy and radiotherapy has drastically reduced the need for a debilitating and disfiguring surgery, treatment related toxicities are often difficult to control. Acute toxicities include mucositis, skin desquamation, depression, cachexia, fatigue and nausea and vomiting. Failure to control these symptoms can adversely affect the patient's ability to complete their treatment regimen. Although there are many promising new treatments in the area of symptom management for this patient population, a review of the literature reflects the need for more research.
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Heidi
authors.initials: H
authors.lastname: Mason
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Mary Beth
authors.initials: MB
authors.lastname: DeRubeis
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Nancy
authors.initials: N
authors.lastname: Burke
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Melissa
authors.initials: M
authors.lastname: Shannon
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Danielle
authors.initials: D
authors.lastname: Karsies
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Gregory
authors.initials: G
authors.lastname: Wolf
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Avi
authors.initials: A
authors.lastname: Eisbruch
authors.affiliation: Heidi Mason, Mary Beth DeRubeis, Nancy Burke, Melissa Shannon, Danielle Karsies, Gregory Wolf, Avi Eisbruch, Francis Worden, University of Michigan School of Nursing, Ann Arbor, MI 48109-5482, United States.
authors.forename: Francis
authors.initials: F
authors.lastname: Worden
keywords: Cachexia; Chemoradiotherapy; Depression; Desquamation; Fatigue; Head and neck cancer; Mucositis; Nausea; Vomiting