title: Coexistence of Multiple Ileal Neuroendocrine Tumors and Idiopathic Myointimal Hyperplasia of Mesenteric Veins: Coincidence or Consequence? Case Report and Review of Literature.
abstract: In the present case, we report the association of multiple ileal neuroendocrine tumors and idiopathic myointimal hyperplasia of the mesenteric veins, 2 rare conditions that could have an etiopathogenetic relationship. Idiopathic myointimal hyperplasia of mesenteric veins implies a near-total obliteration of venular vessels, which can lead to hypoxic disorders. Hypoxia in tumors is associated with increased metastatic potential and resistance to radiotherapy and chemotherapy. Herein we speculated on the existence of a relationship between hypoxia and multiple location of neuroendocrine tumors.
authors.affiliation: University of Naples Federico II, Naples, Italy eliaguadagno84@gmail.com.
authors.forename: Elia
authors.initials: E
authors.lastname: Guadagno
authors.affiliation: University of Naples Federico II, Naples, Italy.
authors.forename: Marialaura
authors.initials: M
authors.lastname: Del Basso De Caro
authors.affiliation: University of Naples Federico II, Naples, Italy.
authors.forename: Ester
authors.initials: E
authors.lastname: Del Prete
authors.affiliation: University of Naples Federico II, Naples, Italy.
authors.forename: Francesco Paolo
authors.initials: FP
authors.lastname: D'Armiento
authors.affiliation: University of Naples Federico II, Naples, Italy.
authors.forename: Severo
authors.initials: S
authors.lastname: Campione
mesh_terms: D015687:Cell Hypoxia; D005260:Female; D006801:Humans; D006965:Hyperplasia / Q000150:complications / Q000473:pathology; D007078:Ileal Neoplasms / Q000150:complications* / Q000473:pathology; D008642:Mesenteric Veins / Q000473:pathology*; D008875:Middle Aged; D018358:Neuroendocrine Tumors / Q000150:complications* / Q000473:pathology; D017539:Tunica Intima / Q000473:pathology*
keywords: hypoxia; myointimal hyperplasia; neuroendocrine tumors; veins