title: [Preoperative Use of Tolvaptan in a Patient with Constrictive Pericarditis].
abstract: Tolvaptan is a new selective vasopression V2-receptor antagonist. We report our experience with a use of tolvaptan for preoperative fluid management in a patient with severe constrictive pericarditis. A 66-year-old man presented with heart failure symptoms derived from constrictive pericarditis. Chest X-ray showed right pleural effusion and chest computed tomography demonstrated severe pericardial calcification. Despite that he received optimal conventional medical treatments, his hemodynamic condition further exacerbated during hospitalization. We administered tolvaptan in an attempt to optimize preoperative fluid management. Tolvaptan was found to be remarkably effective in that regard. The body weight decreased and the heart failure symptoms improved. Pericardiectomy was performed successfully, and he recovered uneventfully.
authors.affiliation: Division of Cardiovascular Surgery, Tohoku University, Graduate School of Medicine, Sendai, Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Kawatsu
authors.forename: Shingo
authors.initials: S
authors.lastname: Takahara
authors.forename: Kou
authors.initials: K
authors.lastname: Sakatsume
authors.forename: Keisuke
authors.initials: K
authors.lastname: Kanda
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Suzuki
authors.forename: Shintaro
authors.initials: S
authors.lastname: Katahira
authors.forename: Hidenori
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Osamu
authors.initials: O
authors.lastname: Adachi
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Akiyama
authors.forename: Kiichiro
authors.initials: K
authors.lastname: Kumagai
authors.forename: Shunsuke
authors.initials: S
authors.lastname: Kawamoto
authors.forename: Yoshikatsu
authors.initials: Y
authors.lastname: Saiki
mesh_terms: D000368:Aged; D065092:Antidiuretic Hormone Receptor Antagonists / Q000627:therapeutic use; D001552:Benzazepines / Q000627:therapeutic use*; D001835:Body Weight / Q000187:drug effects; D006801:Humans; D008297:Male; D010494:Pericarditis, Constrictive / Q000150:complications / Q000601:surgery*; D010996:Pleural Effusion / Q000209:etiology / Q000601:surgery; D011300:Preoperative Care; D000077602:Tolvaptan; D014057:Tomography, X-Ray Computed
chemical_list: D065092:Antidiuretic Hormone Receptor Antagonists; D001552:Benzazepines; D000077602:Tolvaptan