title: MYCN Transforms Prostate Epithelium to Neuroendocrine Prostate Cancer.
abstract: Overexpression of MYCN in normal basal prostate cells drives formation of metastatic NEPC.
mesh_terms: D064096:Aurora Kinase A / Q000037:antagonists & inhibitors; D002471:Cell Transformation, Neoplastic / Q000235:genetics* / Q000378:metabolism; D018450:Disease Progression; D004848:Epithelium / Q000378:metabolism* / Q000473:pathology*; D006801:Humans; D008297:Male; D000071447:N-Myc Proto-Oncogene Protein / Q000235:genetics* / Q000378:metabolism; D009362:Neoplasm Metastasis; D018358:Neuroendocrine Tumors / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D011471:Prostatic Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology; D047428:Protein Kinase Inhibitors / Q000494:pharmacology
chemical_list: D000071447:N-Myc Proto-Oncogene Protein; D047428:Protein Kinase Inhibitors; D064096:Aurora Kinase A