title: Novel t(1;3)(q21,p21) translocation in a basal cell adenocarcinoma of the parotid gland: potential association with tumorigenesis.
abstract: We report a rare translocation involving chromosomes 1q23 and 3p21 regions in a basaloid salivary carcinoma. Our case together with a previously reported instance of translocation involving chromosome 1q 21-24 region defines a specific chromosomal segment that may house a gene associated with the development of a subset of basaloid salivary tumors.
authors.affiliation: Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
authors.forename: Karan
authors.initials: K
authors.lastname: Saluja
authors.affiliation: Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030.
authors.forename: Pulivarthi H
authors.initials: PH
authors.lastname: Rao
authors.affiliation: Department of Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030.
authors.forename: Jeffery N
authors.initials: JN
authors.lastname: Myers
authors.affiliation: Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030. Electronic address: anaggar@mdanderson.org.
authors.forename: Adel K
authors.initials: AK
authors.lastname: El-Naggar
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D002878:Chromosomes, Human, Pair 1; D002893:Chromosomes, Human, Pair 3; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D007621:Karyotyping; D008875:Middle Aged; D010307:Parotid Neoplasms / Q000235:genetics* / Q000473:pathology / Q000601:surgery; D010641:Phenotype; D014178:Translocation, Genetic
keywords: Adenocarcinoma; Adenoma; Basal cell; Salivary tumor; Translocation