title: Design of an Immersion Vaccine Against Aeromonad Septicemia in Perch (Perca fluviatilis L.).
abstract: The production of an immersion vaccine and the vaccination procedure to immunize fry of perch (Perca fluviatilis L.) against pathogenic Aeromonas sobria that harbor a type III secretion system is described. The vaccine, based on chemically inactivated A. sobria, enables rapid vaccination of a large number of fish by immersion of fry in an aqueous vaccine suspension during 5 min, giving them high protection during fattening under open water conditions in a freshwater lake for at least 4 months.
authors.affiliation: Institute of Veterinary Bacteriology, Vetsuisse, University of Bern, Laenggassstrasse 122, 3001, Bern, Switzerland. joachim.frey@vetsuisse.unibe.ch.
authors.forename: Joachim
authors.initials: J
authors.lastname: Frey
authors.affiliation: Institute of Veterinary Bacteriology, Vetsuisse, University of Bern, Laenggassstrasse 122, 3001, Bern, Switzerland.|Clinical Research Department, London School of Hygiene and Tropical Medicine, London, UK.
authors.forename: Sarah E
authors.initials: SE
authors.lastname: Burr
authors.affiliation: Centre for Fish and Wildlife Health, Vetsuisse, University of Bern, Bern, Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Wahli
mesh_terms: D000333:Aeromonas / Q000276:immunology* / Q000502:physiology; D000818:Animals; D000942:Antigens, Bacterial / Q000276:immunology; D001428:Bacterial Vaccines / Q000276:immunology*; D010471:Perches / Q000382:microbiology*; D014611:Vaccination
chemical_list: D000942:Antigens, Bacterial; D001428:Bacterial Vaccines
keywords: Aeromonad septicemia; Immersion vaccination; Long term protection; Motile Aeromonas species; Type III secretion