title: Identification of novel exonic mobile element insertions in epithelial ovarian cancers.
abstract: Mobile elements comprise about half of the human genome. Three active mobile element families (L1, Alu, and SVA) possibly cause diseases such as cancer. We conducted mobile element insertion (MEI) profiling of 44 epithelial ovarian cancers using exome-sequencing data. We identified a total of 106 MEIs using the Mobster program, 8 of which were novel exonic MEIs.
authors.affiliation: Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
authors.forename: Takahide
authors.initials: T
authors.lastname: Hayano
authors.affiliation: Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
authors.forename: Shiro
authors.initials: S
authors.lastname: Yamada
authors.affiliation: Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Hosomichi
authors.affiliation: Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Nakaoka
authors.affiliation: Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
authors.forename: Kosuke
authors.initials: K
authors.lastname: Yoshihara
authors.affiliation: Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
authors.forename: Sosuke
authors.initials: S
authors.lastname: Adachi
authors.affiliation: Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
authors.forename: Katsunori
authors.initials: K
authors.lastname: Kashima
authors.affiliation: Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan; Niigata Medical Center Hospital, Niigata, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences , Niigata, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Enomoto
authors.affiliation: Division of Human Genetics, National Institute of Genetics , Mishima, Japan.
authors.forename: Ituro
authors.initials: I
authors.lastname: Inoue