title: [Insulin therapy: as early as possible].
abstract: The guidelines of the leading national and international diabetes associations enable the early use of insulin in the treatment of type 2 diabetes, in particular, if HbA1c is markedly increased or a rapid metabolic normalisation is aspired. The early use of insulin, and particularly of long-acting insulin analogues, is effective and safe. A short-term aggressive insulin treatment as first-line therapy of a newly diagnosed type 2 diabetes has the potential to induce a prolonged recovery of beta-cell function and improvement of insulin sensitivity.
authors.forename: Karsten
authors.initials: K
authors.lastname: Müssig
mesh_terms: D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D006801:Humans; D006943:Hyperglycemia / Q000188:drug therapy; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use*; D017410:Practice Guidelines as Topic; D013997:Time Factors
chemical_list: D007004:Hypoglycemic Agents; D007328:Insulin