title: Molecular Epidemiology and Genetic Characteristics of Various blaPER Genes in Shanghai, China.
abstract: We describe the genetic characteristics and possible transmission mechanism of blaPER in 25 clinical Gram-negative bacilli in Shanghai. blaPER, including blaPER-1, blaPER-3, and blaPER-4, was located chromosomally or in different plasmids. Tn1213 harboring blaPER-1 was first identified in two Proteus mirabilis isolates in China. The other blaPER variants were preceded by an ISCR1 element inside the complex class 1 integron associated with IS26, Tn21, Tn1696, and a miniature inverted-repeat transposable element.
authors.affiliation: Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Lianyan
authors.initials: L
authors.lastname: Xie
authors.affiliation: Department of Critical Care Medicine, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Fangfang
authors.initials: F
authors.lastname: Zhang
authors.affiliation: Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Lizhong
authors.initials: L
authors.lastname: Han
authors.affiliation: Department of Medical Microbiology and Parasitology, Institutes of Medical Sciences, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Xiaokui
authors.initials: X
authors.lastname: Guo
authors.affiliation: Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Yuxing
authors.initials: Y
authors.lastname: Ni
authors.affiliation: Department of Clinical Microbiology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China 13671578899@126.com.
authors.forename: Jingyong
authors.initials: J
authors.lastname: Sun
mesh_terms: D000151:Acinetobacter Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D040981:Acinetobacter baumannii / Q000235:genetics* / Q000302:isolation & purification; D002681:China / Q000453:epidemiology; D002876:Chromosomes, Bacterial / Q000737:chemistry; D004251:DNA Transposable Elements; D015870:Gene Expression; D006801:Humans; D032023:Integrons; D017720:Molecular Epidemiology; D010957:Plasmids / Q000737:chemistry / Q000378:metabolism*; D011512:Proteus Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D011513:Proteus mirabilis / Q000235:genetics* / Q000302:isolation & purification; D011552:Pseudomonas Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D011550:Pseudomonas aeruginosa / Q000235:genetics* / Q000302:isolation & purification; D012480:Salmonella Infections / Q000453:epidemiology / Q000382:microbiology / Q000635:transmission; D019779:Salmonella enterica / Q000235:genetics* / Q000302:isolation & purification; D001618:beta-Lactamases / Q000235:genetics*
chemical_list: D004251:DNA Transposable Elements; D001618:beta-Lactamases