title: Enantioselective Synthesis of Ring-Fused Spiroannulated 1,2,3-Thiadiazole Derivatives.
abstract: An organocatalytic enantioselective domino α-amination/oxidative coupling/cyclization of thioamides to azodicarboxylates catalyzed by an easily available organic catalyst has been developed. The key step, oxidative coupling, is smoothly fulfilled in air. Optically active spiroannulated 1,2,3-thiadiazole derivatives are obtained with high yields and enantioselectivities for the first time.
authors.affiliation: Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry and Life Science, Zhejiang Normal University , Jinhua 321004, P. R. China.
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Zeng
authors.affiliation: Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry and Life Science, Zhejiang Normal University , Jinhua 321004, P. R. China.
authors.forename: Jian-Wu
authors.initials: JW
authors.lastname: Xie