title: Brazilian experience of the influence of endovascular treatment on headache in patients with ruptured intracranial aneurysms.
abstract: BACKGROUND
  The characteristics of primary headaches in patients with ruptured brain aneurysm embolization have not been well understood to date.
  
  
  OBJECTIVE
  This study was conducted to evaluate the influence of endovascular treatment (EVT) of ruptured intracranial aneurysm (RIA) and the pattern of previous primary headache.
  
  
  METHODS
  We evaluated the pattern of headache in patients who suffered a RIA and EVT within one year before the rupture, and prospectively evaluated the characteristics of headache for up to 12 months after EVT. Sixty patients were evaluated and a questionnaire about headache was applied at the time of admission. These patients were contacted 3, 6 and 12 months after treatment to complete the study by filling out follow-up questionnaire on the headache.
  
  
  RESULTS
  Thirty-seven patients had headache before the rupture, 16 with tension-type headache (TTH), 11 with migraine without aura, nine with migraine with aura with and one with non-specific characteristics. There was a significant reduction in the frequency of pain for up to 12 months for patients with TTH (P < 0.001) and migraine without aura (P = 0.012), but there was a reduction in pain intensity over the same period in TTH (P = 0.002), migraine with aura (P = 0.004) and migraine without aura (P < 0.001).
  
  
  CONCLUSIONS
  There was a reduction of the primary headache after endovascular treatment of ruptured brain aneurysm.
authors.affiliation: Internal Medicine Department, Neurology Service, Headache Specialty, Hospital de Clínicas, Federal University of Paraná (UFPR), Curitiba, Brazil.
authors.forename: B B
authors.identifier: http://orcid.org/0000-0003-1870-4893
authors.initials: BB
authors.lastname: Esmanhotto
authors.affiliation: Internal Medicine Department, Neurology Service, Headache Specialty, Hospital de Clínicas, Federal University of Paraná (UFPR), Curitiba, Brazil.
authors.forename: E J
authors.initials: EJ
authors.lastname: Piovesan
authors.affiliation: Internal Medicine Department, Neurology Service, Headache Specialty, Hospital de Clínicas, Federal University of Paraná (UFPR), Curitiba, Brazil.
authors.forename: M C
authors.initials: MC
authors.lastname: Lange
mesh_terms: D000328:Adult; D017542:Aneurysm, Ruptured / Q000453:epidemiology / Q000628:therapy*; D001938:Brazil / Q000453:epidemiology; D004621:Embolization, Therapeutic / Q000706:statistics & numerical data*; D005260:Female; D051270:Headache Disorders, Primary / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D002532:Intracranial Aneurysm / Q000453:epidemiology / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D017063:Outcome Assessment, Health Care; D055815:Young Adult
keywords: cerebral aneurysm; migraine; primary headache; tension-type headache