title: A case report of gastric cancer with brain metastasis: Rare peripheral nervous system symptoms.
abstract: Gastric cancer with brain metastasis is rare. The present study reports a case of gastric cancer with isolated brain metastasis 1 year after gastrectomy. To the best of our knowledge, there have been no prior reports of solitary brain metastasis from gastric cancer with peripheral nervous system symptoms. A distal gastrectomy was performed on a 60-year-old male patient with gastric cancer in November 2012. Postoperative pathological analysis revealed a moderately differentiated adenocarcinoma with tumor invasion into the serosa and metastasis to one dissected lymph node. No abnormalities were found at follow-up examination. However, a tumor representing metastasis to the brain was recognized by a cranial enhanced magnetic resonance imaging examination 1 year after gastrectomy, which was performed when the patient exhibited numbness and thigmesthesia. The patient was administered 30 Gy of stereotactic radiotherapy, delivered in 5 fractions. The patient succumbed to disease 10 months subsequent to undergoing radiotherapy. This case report suggests that gastric cancer may re-present as brain metastasis with peripheral nervous system symptoms.
authors.affiliation: Department of Integrative Oncology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
authors.forename: Ge-Liang
authors.initials: GL
authors.lastname: Yang
authors.affiliation: Department of General Surgery, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
authors.forename: Tian-Hang
authors.initials: TH
authors.lastname: Luo
authors.affiliation: Department of Integrative Oncology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
authors.forename: Hui-Qing
authors.initials: HQ
authors.lastname: Zhang
authors.affiliation: Department of Integrative Oncology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
authors.forename: Chang-Quan
authors.initials: CQ
authors.lastname: Ling
authors.affiliation: Department of Integrative Oncology, Changhai Hospital, Second Military Medical University, Shanghai 200433, P.R. China.
authors.forename: Bai
authors.initials: B
authors.lastname: Li
keywords: brain metastasis; gastric cancer; peripheral nervous system symptoms