title: Antibiotic resistance and polymorphism in the quinolone resistance-determining region of Campylobacter spp. isolated from 1-day-old ducklings.
abstract: Thirty-three isolates of Campylobacter coli and three isolates of Campylobacter jejuni were recovered from 150 1-day-old ducklings. All isolates were sensitive to chloramphenicol and amikacin, but resistant to sulfamethoxazole-trimethoprim (SXT) by the disc diffusion method. Most isolates were susceptible to tetracycline and erythromycin, but resistant to ofloxacin and ciprofloxacin. Of the 33 C. coli isolates, nine were positive for the tetracycline resistance gene tet(O), although only two of these were resistant to tetracycline in the disc diffusion test. None of the isolates possessed mutations in the quinolone resistance-determining region (QRDR) of the gyrA gene infrequently linked to FQ-resistance. The finding indicated that ducklings may be a source of antibiotic resistant Campylobacter spp. with potential poultry and public health hazard.
authors.affiliation: Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Ministry of Agriculture and Land Reclamation, Dokki, Giza 12618, Egypt. Electronic address: drengyahmed_2020@yahoo.com.
authors.forename: Engy A
authors.initials: EA
authors.lastname: Hamed
authors.affiliation: Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Ministry of Agriculture and Land Reclamation, Dokki, Giza 12618, Egypt.
authors.forename: Mona A A
authors.initials: MA
authors.lastname: AbdelRahman
authors.affiliation: Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Ministry of Agriculture and Land Reclamation, Dokki, Giza 12618, Egypt.
authors.forename: Azhar G
authors.initials: AG
authors.lastname: Shalaby
authors.affiliation: Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Ministry of Agriculture and Land Reclamation, Dokki, Giza 12618, Egypt.
authors.forename: Mai M
authors.initials: MM
authors.lastname: Morsy
authors.affiliation: Reference Laboratory for Veterinary Quality Control on Poultry Production, Animal Health Research Institute, Ministry of Agriculture and Land Reclamation, Dokki, Giza 12618, Egypt.
authors.forename: Soad A
authors.initials: SA
authors.lastname: Nasef
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001483:Base Sequence; D002167:Campylobacter / Q000187:drug effects* / Q000201:enzymology / Q000235:genetics; D002169:Campylobacter Infections / Q000453:epidemiology / Q000382:microbiology / Q000662:veterinary*; D017000:Campylobacter coli / Q000187:drug effects / Q000201:enzymology / Q000235:genetics; D016123:Campylobacter jejuni / Q000187:drug effects / Q000201:enzymology / Q000235:genetics; D027081:DNA Gyrase / Q000235:genetics*; D024881:Drug Resistance, Bacterial; D004372:Ducks; D004534:Egypt / Q000453:epidemiology; D010802:Phylogeny; D011110:Polymorphism, Genetic; D011201:Poultry Diseases / Q000453:epidemiology* / Q000382:microbiology; D015363:Quinolones / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D015363:Quinolones; D027081:DNA Gyrase
keywords: Antibiotic resistance; Campylobacter spp; Ducklings; gyrA; tet(O)