title: Cardiac Manifestation of Acute Lymphoblastic Leukemia.
abstract: Here, we report on a 38-year-old man with unclear right heart failure. Imaging with cardiac MRI and combined PET/CT with F-FDG revealed a hypermetabolic mass extending from the right ventricle to the atrium. In addition, intense glucose utilization throughout the bone marrow was noted. Biopsies of both bone marrow and cardiac mass were performed and revealed precursor B-cell acute lymphoblastic leukemia with gross leukemic infiltration of the myopericardium, a rare manifestation of acute lymphoblastic leukemia at initial diagnosis.
authors.affiliation: From the *Department of Nuclear Medicine, †Comprehensive Heart Failure Center, University Hospital Würzburg; ‡Institute for Pathology, University of Würzburg; and §Institute for Radiology, University Hospital Würzburg, Würzburg, Germany.
authors.forename: Rudolf A
authors.initials: RA
authors.lastname: Werner
authors.forename: Martina
authors.initials: M
authors.lastname: Rudelius
authors.forename: Annette
authors.initials: A
authors.lastname: Thurner
authors.forename: Takahiro
authors.initials: T
authors.lastname: Higuchi
authors.forename: Constantin
authors.initials: C
authors.lastname: Lapa
mesh_terms: D000328:Adult; D006333:Heart Failure / Q000000981:diagnostic imaging* / Q000209:etiology; D006801:Humans; D017254:Leukemic Infiltration / Q000000981:diagnostic imaging; D008279:Magnetic Resonance Imaging; D008297:Male; D064847:Multimodal Imaging; D010496:Pericardium / Q000473:pathology; D000072078:Positron Emission Tomography Computed Tomography; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000150:complications / Q000000981:diagnostic imaging*