title: DPABI: Data Processing & Analysis for (Resting-State) Brain Imaging.
abstract: Brain imaging efforts are being increasingly devoted to decode the functioning of the human brain. Among neuroimaging techniques, resting-state fMRI (R-fMRI) is currently expanding exponentially. Beyond the general neuroimaging analysis packages (e.g., SPM, AFNI and FSL), REST and DPARSF were developed to meet the increasing need of user-friendly toolboxes for R-fMRI data processing. To address recently identified methodological challenges of R-fMRI, we introduce the newly developed toolbox, DPABI, which was evolved from REST and DPARSF. DPABI incorporates recent research advances on head motion control and measurement standardization, thus allowing users to evaluate results using stringent control strategies. DPABI also emphasizes test-retest reliability and quality control of data processing. Furthermore, DPABI provides a user-friendly pipeline analysis toolkit for rat/monkey R-fMRI data analysis to reflect the rapid advances in animal imaging. In addition, DPABI includes preprocessing modules for task-based fMRI, voxel-based morphometry analysis, statistical analysis and results viewing. DPABI is designed to make data analysis require fewer manual operations, be less time-consuming, have a lower skill requirement, a smaller risk of inadvertent mistakes, and be more comparable across studies. We anticipate this open-source toolbox will assist novices and expert users alike and continue to support advancing R-fMRI methodology and its application to clinical translational studies.
authors.affiliation: Key Laboratory of Behavioral Science and Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, Beijing, 100101, China. ycg.yan@gmail.com.|Department of Child and Adolescent Psychiatry, NYU Langone Medical Center School of Medicine, New York, NY, USA. ycg.yan@gmail.com.
authors.forename: Chao-Gan
authors.initials: CG
authors.lastname: Yan
authors.affiliation: State Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
authors.forename: Xin-Di
authors.initials: XD
authors.lastname: Wang
authors.affiliation: Key Laboratory of Behavioral Science and Magnetic Resonance Imaging Research Center, Institute of Psychology, Chinese Academy of Sciences, 16 Lincui Road, Chaoyang District, Beijing, 100101, China.
authors.forename: Xi-Nian
authors.initials: XN
authors.lastname: Zuo
authors.affiliation: Center for Cognition and Brain Disorders, Hangzhou Normal University, Hangzhou, China.|Zhejiang Key Laboratory for Research in Assessment of Cognitive Impairments, Hangzhou, Zhejiang, China.|Department of Psychology, College of Education, Hangzhou Normal University, Hangzhou, China.
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Zang
mesh_terms: D000818:Animals; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D008279:Magnetic Resonance Imaging; D015203:Reproducibility of Results; D012815:Signal Processing, Computer-Assisted; D012984:Software
keywords: Data processing; Quality control; Resting-state fMRI; Standardization; Statistical analysis