title: Comparing the Trend of Physical Activity and Caloric Intake between Lipid-Lowering Drug Users and Nonusers among Adults with Dyslipidemia: Korean National Health and Nutrition Examination Surveys (2010-2013).
abstract: BACKGROUND
  The purpose of this study was to compare the physical activity and caloric intake trends of lipid-lowering drug users with those of non-users among Korean adults with dyslipidemia.
  
  
  METHODS
  This study was a repeated cross-sectional study with a nationally representative sample of 2,635 Korean adults with dyslipidemia based on the 2010-2013 Korea National Health and Nutrition Examination Survey. Physical activity was assessed using the International Physical Activity Questionnaire, and caloric intake was estimated through 24-hour dietary recall. All statistical analyses were conducted using IBM SPSS ver. 21.0 (IBM Co., Armonk, NY, USA). The changes in physical activity and caloric intake were investigated for lipid-lowering drug users and non-users using generalized linear models.
  
  
  RESULTS
  The proportion of lipid-lowering drug users in the 2010-2013 survey population increased from 3.5% to 5.0% (P<0.001). Among adults of dyslipidemia, total of 1,562 participants (56.6%) reported taking lipid-lowering drugs, and 1,073 (43.4%) reported not taking lipid-lowering drugs. Drug users were more likely to be older and less educated and to have a diagnosis of diabetes, higher body mass index, and lower low density lipoprotein cholesterol level. Physical activity trends were tested separately for the lipid-lowering drug users and non-users, and a significant decrease was found among the drug users during the study period. Physical activity among the drug users in 2013 was 38% lower (1,357.3±382.7 metabolic equivalent [MET]; P for trend=0.002) than in 2010 (2,201.4±442.6 MET). In contrast, there was no statistically significant difference between drug users and non-users in the trend of caloric intake during the same period.
  
  
  CONCLUSIONS
  Physical activity significantly decreased among lipid-lowering drug users between 2010 and 2013, which was not observed among non-users. The importance of physical activity may need to be re-emphasized for lipid-lowering drug users.
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jin-Young
authors.initials: JY
authors.lastname: Oh
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Lan
authors.initials: L
authors.lastname: Chekal
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Se-Won
authors.initials: SW
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jee-Yon
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Family Medicine, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Duk-Chul
authors.initials: DC
authors.lastname: Lee
keywords: Drug Users; Dyslipidemias; Energy Intake; Physical Activity