title: All-Polyethylene Tibial Components: An Analysis of Long-Term Outcomes and Infection.
abstract: There is debate regarding tibial component modularity and composition in total knee arthroplasty (TKA). Biomechanical studies have suggested improved stress distribution in metal-backed tibias; however, these results have not translated clinically. The purpose of this study was to analyze the outcomes of all-polyethylene components and to compare the results to those with metal-backed components.
  
  
  
  We reviewed 31,939 patients undergoing a primary TKA over a 43-year period (1970-2013). There were 28,224 (88%) metal-backed and 3715 (12%) all-polyethylene tibial components. The metal-backed and all-polyethylene groups had comparable demographics with respect to gender, age and body mass index (BMI). Mean follow-up was 7 years.
  
  
  
  The mean survival for all primary TKAs at the 5-, 10-, 20- and 30-year time points was 95%, 89%, 73%, and 57%, respectively. All-polyethylene tibial components were found to have a significantly improved (P < .0001) survivorship when compared with their metal-backed counterparts. All-polyethylene tibial components were also found to have a significantly lower rate of infection, instability, tibial component loosening, and periprosthetic fracture. The all-polyethylene group had improved survival rates in all age groups, except in patients 85 years old or greater, where there was no significant difference. All-polyethylene tibial components had improved survival for all BMI groups except in the morbidly obese (BMI ≥ 40) where there was no significant difference.
  
  
  
  All-polyethylene tibial components had significantly improved implant survival, reduced rates of postoperative infection, fracture, and tibial component loosening. All polyethylene should be considered for most of the patients, regardless of age and BMI.
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Matthew T
authors.initials: MT
authors.lastname: Houdek
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Eric R
authors.initials: ER
authors.lastname: Wagner
authors.affiliation: Mayo Graduate School of Medical Education, Rochester, Minnesota.
authors.forename: Cody C
authors.initials: CC
authors.lastname: Wyles
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Chad D
authors.initials: CD
authors.lastname: Watts
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Cass
authors.affiliation: Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota.
authors.forename: Robert T
authors.initials: RT
authors.lastname: Trousdale
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D019645:Arthroplasty, Replacement, Knee; D001696:Biomechanical Phenomena; D015992:Body Mass Index; D005260:Female; D005500:Follow-Up Studies; D050723:Fractures, Bone / Q000601:surgery; D006801:Humans; D053208:Kaplan-Meier Estimate; D007720:Knee Prosthesis; D008297:Male; D008670:Metals; D008875:Middle Aged; D009767:Obesity, Morbid / Q000601:surgery*; D020959:Polyethylene / Q000737:chemistry*; D011446:Prospective Studies; D011474:Prosthesis Design; D012042:Registries; D013314:Stress, Mechanical; D013977:Tibia / Q000601:surgery*; D013997:Time Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D008670:Metals; D020959:Polyethylene
keywords: all-polyethylene tibia; infection; metal backed; outcome; total knee arthroplasty