title: Inflammatory pseudotumor (IPT)-surgical cure of an inflammatory syndrome.
abstract: We report on four female adolescents, who presented with inflammatory symptoms. Extensive diagnostic workup revealed tumors on different locations. After surgical removal, clinical and laboratory signs of inflammation disappeared rapidly. On histology, the tumors showed a mixture of inflammatory cells characteristic of inflammatory pseudotumors in three of the patients.
  
  
  CONCLUSIONS
  In patients with unclear inflammatory symptoms, inflammatory pseudotumor should be added to the differential diagnosis.
  
  
  BACKGROUND
  • The inflammatory pseudotumor (IPT) is a mostly benign myofibroblastic tumor of the soft tissue and causes inflammatory symptoms. What is new: • IPTs have may wider than hitherto defined histologic features. Removal of IPT is curative.
authors.affiliation: Children's Hospital, Infectious Diseases and Immunology, University of Munich, Munich, Germany.
authors.forename: A
authors.initials: A
authors.lastname: Rack
authors.affiliation: Children's Hospital, Infectious Diseases and Immunology, University of Munich, Munich, Germany.
authors.forename: B H
authors.initials: BH
authors.lastname: Belohradsky
authors.affiliation: Children's Hospital, Pediatric Surgery, University of Munich, Munich, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Grantzow
authors.affiliation: Children's Hospital, Pediatric Surgery, University of Munich, Munich, Germany.
authors.forename: D V
authors.initials: DV
authors.lastname: Schweinitz
authors.affiliation: Department of Nuclear Medicine, University of Munich, Munich, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Pfluger
authors.affiliation: Department of Pediatric Radiology, University of Munich, Munich, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Kammer
authors.affiliation: Children's Hospital, Vivantes Klinik, Berlin, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Girschick
authors.affiliation: Institute of Pathology, University of Munich, Munich, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Horst
authors.affiliation: Department of Pediatrics, Hospital of Braunau, Braunau, Austria. uwe.wintergerst@khbr.at.
authors.forename: U
authors.initials: U
authors.lastname: Wintergerst
mesh_terms: D000293:Adolescent; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002648:Child; D003937:Diagnosis, Differential; D005260:Female; D006104:Granuloma, Plasma Cell / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D006801:Humans; D049268:Positron-Emission Tomography
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents
keywords: Fever of unknown origin; Inflammatory pseudotumor; Inflammatory symptoms; Recurrent fever