title: The Influence of Pre-natal Supplement Initiation on Preterm Birth Among Majority Hispanic Women in Los Angeles County: The Role of Nativity.
abstract: Objectives Despite being encouraged to take pre-natal supplements, suboptimal micronutrient intake is common in pregnancy, especially among Hispanic women. In this study, we assessed whether initiation and timing of pre-natal vitamin use influences the risk of preterm birth. Methods Women who gave birth to singletons in 2003 in Los Angeles County, California, were enrolled into a population-based case-control study. Focusing on non-Hispanic white and Hispanic women, associations between timing of pre-natal supplement use and preterm birth were assessed using logistic regression. Results Among Hispanic mothers, the odds of preterm birth increased the later a woman initiated pre-natal supplement use in pregnancy. The magnitude of this association was larger in US-born compared to foreign-born Hispanic women. Conclusions These findings suggest that nativity may modify the relationship between pre-natal supplement use and preterm birth possibly due to underlying differences in diet composition of Hispanic women by place of birth.
authors.affiliation: Department of Epidemiology, University of California, Los Angeles, Fielding School of Public Health, Box 951772, Los Angeles, CA, 90095, USA. vivianhelena@ucla.edu.
authors.forename: Vivian H
authors.initials: VH
authors.lastname: Alfonso
authors.affiliation: Department of Community Health Sciences, University of California, Los Angeles, Fielding School of Public Health, Box 951772, Los Angeles, CA, 90095, USA.
authors.forename: Ondine
authors.initials: O
authors.lastname: von Ehrenstein
authors.affiliation: Department of Epidemiology, University of California, Los Angeles, Fielding School of Public Health, Box 951772, Los Angeles, CA, 90095, USA.
authors.forename: Gretchen
authors.initials: G
authors.lastname: Bandoli
authors.affiliation: Department of Epidemiology, University of California, Los Angeles, Fielding School of Public Health, Box 951772, Los Angeles, CA, 90095, USA.
authors.forename: Beate
authors.initials: B
authors.lastname: Ritz
mesh_terms: D000328:Adult; D002140:California / Q000453:epidemiology; D016022:Case-Control Studies; D019587:Dietary Supplements; D005006:Ethnicity / Q000706:statistics & numerical data; D005260:Female; D006306:Health Surveys; D006630:Hispanic or Latino / Q000706:statistics & numerical data*; D006801:Humans; D007231:Infant, Newborn; D011159:Population Surveillance / Q000379:methods*; D011203:Poverty; D016742:Preconception Care; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth / Q000453:epidemiology / Q000208:ethnology; D011295:Prenatal Care; D014815:Vitamins / Q000008:administration & dosage*; D044465:White People / Q000706:statistics & numerical data*
chemical_list: D014815:Vitamins
keywords: Folic acid; Maternal public health; Nutritional epidemiology; Preconception nutrition; Prenatal nutrition; Preterm birth