title: The role of the mean platelet volume and neutrophil-to-lymphocyte ratio in peritonsillar abscesses.
abstract: BACKGROUND
  Peritonsillar abscess is a serious infectious disease of the tonsillar tissue. Treatment generally requires both medical and surgical approaches to relieve the symptoms. Recently, in addition to clinical follow-up, some inflammatory markers, such as the mean platelet volume and neutrophil-to-lymphocyte ratio, have been considered to be additional inflammatory monitoring markers in inflammatory diseases.
  
  
  OBJECTIVE
  The aim of this study was to describe the role of mean platelet volume and neutrophil-to-lymphocyte ratio in patients with peritonsillar abscess.
  
  
  METHODS
  A retrospective study was conducted in 88 patients with peritonsillar abscess and 88 healthy individuals. We analyzed the white blood cell count, neutrophil count, lymphocyte count, platelet count, C-reactive protein, mean platelet volume and neutrophil-to-lymphocyte ratio values and compared them among the patient and control groups.
  
  
  RESULTS
  The mean platelet volume levels were significantly higher in the peritonsillar abscess pretreatment group than in the peritonsillar abscess posttreatment group and the control group. A mean platelet volume value of 8.7 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 75%, 65.9%, 68% and 72%, respectively. The neutrophil-to-lymphocyte ratio levels were significantly higher in the peritonsillar abscess pretreatment group than in the peritonsillar abscess post-treatment group and the control group. A neutrophil-to-lymphocyte ratio value of 3.08 was the optimal cut-off value for evaluating the sensitivity, specificity, positive predictive value and negative predictive value of 90.9%, 90.9%, 90.9% and 90.9%, respectively. While the white blood cell count, neutrophil count, lymphocyte count and C-reactive protein values were significantly different among the patient and control groups (p<0.05), the platelet count was not significantly different among the patient and control groups (p>0.05).
  
  
  CONCLUSIONS
  The mean platelet volume and neutrophil-to-lymphocyte ratio values made us think that these parameters were quick, inexpensive and reliable inflammatory follow-up parameters and could be easily integrated into daily practice for peritonsillar abscess treatment except platelet count.
authors.affiliation: Konya Education and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey. Electronic address: drmehmetsenturk@gmail.com.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Şentürk
authors.affiliation: Konya Education and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey.
authors.forename: İsa
authors.initials: İ
authors.lastname: Azgın
authors.affiliation: Konya Education and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey.
authors.forename: Gültekin
authors.initials: G
authors.lastname: Övet
authors.affiliation: Konya Education and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey.
authors.forename: Necat
authors.initials: N
authors.lastname: Alataş
authors.affiliation: Konya Education and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey.
authors.forename: Betül
authors.initials: B
authors.lastname: Ağırgöl
authors.affiliation: Konya Education and Research Hospital, Department of Otolaryngology Head and Neck Surgery, Konya, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Yılmaz
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D018655:Lymphocyte Count; D008297:Male; D063847:Mean Platelet Volume; D009504:Neutrophils; D000039:Peritonsillar Abscess / Q000097:blood* / Q000473:pathology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers
keywords: Abscesso periamigdaliano; Mean platelet volume; Neutrophil-to-lymphcyte rate; Peritonsillar abscess; Relação neutrófilos/linfócitos; Tratamento; Treatment; Volume plaquetário médio