title: Pulmonary arterial hypertension associated with hereditary hemorrhagic telangiectasia successfully treated with sildenafil.
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Miyake
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan. Electronic address: tafujino@cardiol.med.kyushu-u.ac.jp.
authors.forename: Takeo
authors.initials: T
authors.lastname: Fujino
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: Kohtaro
authors.initials: K
authors.lastname: Abe
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Hosokawa
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: Kisho
authors.initials: K
authors.lastname: Ohtani
authors.affiliation: Department of Bioscience and Genetics, National Cerebral and Cardiovascular Center Research Institute, 5-7-1, Fujishirodai, Suita, Osaka 565-8565, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Morisaki
authors.affiliation: Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center Research Institute, 5-7-1, Fujishirodai, Suita, Osaka 565-8565, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Yamada
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: Taiki
authors.initials: T
authors.lastname: Higo
authors.affiliation: Department of Cardiovascular Medicine, Kyushu University Hospital, 3-1-1, Maidashi, Higashiku, Fukuoka 812-8582, Japan.
authors.forename: Tomomi
authors.initials: T
authors.lastname: Ide
mesh_terms: D030301:Activin Receptors, Type II / Q000235:genetics; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000188:drug therapy* / Q000235:genetics; D008875:Middle Aged; D020125:Mutation, Missense; D010375:Pedigree; D000081029:Pulmonary Arterial Hypertension; D000068677:Sildenafil Citrate / Q000008:administration & dosage*; D013684:Telangiectasis / Q000151:congenital* / Q000188:drug therapy / Q000235:genetics; D016896:Treatment Outcome; D014665:Vasodilator Agents / Q000008:administration & dosage
chemical_list: D014665:Vasodilator Agents; D000068677:Sildenafil Citrate; C425364:ACVRL1 protein, human; D030301:Activin Receptors, Type II
keywords: ACVRL1 gene mutation; Hereditary hemorrhagic telangiectasia; Pulmonary arterial hypertension; Sildenafil