title: Change in choroidal thickness and the relationship with accommodation following myopic excimer laser surgery.
abstract: PurposeTo investigate early changes in choroidal thickness (CT) and the relationship with accommodation after myopic excimer laser surgery.MethodsWe enrolled the right eye of 70 patients with myopia and without other ophthalmic or systemic diseases who were suitable for myopic excimer laser surgery. The CT was measured at the fovea and at distances of 0.5 and 2.5 mm for the following: nasal; temporal; superior; and inferior to the fovea preoperatively and at 1 month postoperatively. Other data collected included demographic information (age, sex, and refractive error), the amplitude of accommodation (AA), intraocular pressure, axial length, corneal thickness, and surgical parameters. The data were analyzed with a paired Student's t-test, stepwise linear regression, and correlation analysis.ResultsThe CT was significantly thicker postoperatively compared with the preoperative CT. The AA significantly decreased postoperatively. The change in the AA was the most significant factor associated with the change in the CT at the fovea. Except for 2.5 mm inferior to the fovea, the increase in the CT at other locations was positively correlated with the decrease in the AA.ConclusionsThe CT increased following myopic excimer laser surgery and the change was most obvious when accompanied by a decrease in the AA early after the surgery.
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: M
authors.identifier: http://orcid.org/0000-0002-6162-7742
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: H
authors.initials: H
authors.lastname: Cheng
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Yuan
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: J
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: R
authors.initials: R
authors.lastname: Me
authors.affiliation: Department of Ophthalmology, Shanghai First People's Hospital, Shanghai JiaoTong University School of Medicine, Shanghai, China.
authors.forename: B
authors.initials: B
authors.lastname: Ke
mesh_terms: D000065:Accommodation, Ocular / Q000502:physiology*; D000328:Adult; D002829:Choroid / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D049008:Keratectomy, Subepithelial, Laser-Assisted / Q000379:methods*; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008297:Male; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D041623:Tomography, Optical Coherence; D055815:Young Adult