title: Vitamin-D measurement in patients with adolescent idiopathic scoliosis.
abstract: Our retrospective study compared vitamin-D levels in 229 patients with adolescent idiopathic scoliosis (AIS) and 389 age-matched controls, and evaluated the correlation between vitamin-D levels and sex, Cobb's angle, and serum levels of calcium (Ca), phosphorus, and alkaline phosphatase in the AIS group. Vitamin-D levels were lower in the AIS group, with no sex-specific effects, indicative of a possible vitamin-D resistance in AIS. Vitamin-D levels correlated positively with Ca levels and negatively with Cobb's angle, indicative of a possible role of vitamin D in the etiopathogenesis of AIS. Patients with AIS should be monitored for vitamin-D deficiency/insufficiency.
authors.affiliation: Departments of aOrthopaedics and Traumatology bSports Medicine, M.H. Metin Sabanci Baltalimani Bone Diseases Training and Research Hospital, Baltalimani, Istanbul, Turkey.
authors.forename: Mehmet B
authors.initials: MB
authors.lastname: Balioglu
authors.forename: Canan
authors.initials: C
authors.lastname: Aydin
authors.forename: Deniz
authors.initials: D
authors.lastname: Kargin
authors.forename: Akif
authors.initials: A
authors.lastname: Albayrak
authors.forename: Yunus
authors.initials: Y
authors.lastname: Atici
authors.forename: Suleyman K
authors.initials: SK
authors.lastname: Tas
authors.forename: Mehmet A
authors.initials: MA
authors.lastname: Kaygusuz
mesh_terms: D000293:Adolescent; D000469:Alkaline Phosphatase / Q000097:blood; D002118:Calcium / Q000097:blood; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012600:Scoliosis / Q000097:blood*; D012737:Sex Factors; D014807:Vitamin D / Q000097:blood*; D014808:Vitamin D Deficiency / Q000097:blood; D055815:Young Adult
chemical_list: D014807:Vitamin D; D000469:Alkaline Phosphatase; D002118:Calcium