title: Application areas of 3D bioprinting.
abstract: Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.
authors.affiliation: Engineering Science and Mechanics Department, The Pennsylvania State University, State College, PA 16802, USA; The Huck Institutes of the Life Sciences, The Pennsylvania State University, State College, PA 16802, USA. Electronic address: ito1@psu.edu.
authors.forename: Ibrahim T
authors.initials: IT
authors.lastname: Ozbolat
authors.affiliation: Engineering Science and Mechanics Department, The Pennsylvania State University, State College, PA 16802, USA; The Huck Institutes of the Life Sciences, The Pennsylvania State University, State College, PA 16802, USA; Department of Pharmacology, Nanchang University, Nanchang, JX 330006, China.
authors.forename: Weijie
authors.initials: W
authors.lastname: Peng
authors.affiliation: Mechanical Engineering Department, Ceyhan Engineering Faculty, Cukurova University, 01330 Adana, Turkey.
authors.forename: Veli
authors.initials: V
authors.lastname: Ozbolat
mesh_terms: D000818:Animals; D035843:Biomedical Research; D062028:Bioprinting; D055808:Drug Discovery; D057166:High-Throughput Screening Assays; D006801:Humans; D009369:Neoplasms; D066330:Printing, Three-Dimensional; D044968:Regenerative Medicine; D023822:Tissue Engineering