title: [HPV DNA genotyping: A study of anogenital, head and neck and skin cancers in a population from west Algerian. HPV detection in different cancers from an Algerian population].
abstract: OBJECTIVE
  To investigate the prevalence of human papillomaviruses (HPV) in cancers located at different sites in patients from west Algerian and collected between 2010 and 2014.
  
  
  METHODS
  Extracted DNA from archival formaldehyde-fixed and paraffin-embedded tissues was provided from 39 anogenital cancers, 10 head and neck cancers and 36 skin cancers. The viral DNA was detected using the INNO-LiPA HPV Genotyping Extra(®) kit.
  
  
  RESULTS
  The prevalence of HPV was 100% in cervical cancers, 40% in vaginal cancers, 17% in vulvar cancers, 33% in anal cancers, 0% in tonsil and larynx cancers and 6.4% in skin squamous cell carcinoma. In cervical cancers, the most prevalent genotypes were HPV16 (52%) and HPV18 (12%) as single infection.
  
  
  CONCLUSIONS
  The overall results agree partially with literature. Extensive research is necessary to promote HPV vaccine to reduce in particular the burden of cervical cancer in Algeria.
authors.affiliation: Université de Tlemcen, laboratoire de microbiologie appliquée à l'agroalimentaire, au biomédical et à l'environnement (LAMAABE), ex. complexe biomédical, Imama, bloc C, BP 119, Tlemcen 13000, Algérie. Electronic address: nahet_amira@hotmail.fr.
authors.forename: Amira
authors.initials: A
authors.lastname: Nahet
authors.affiliation: Université de Tlemcen, laboratoire de microbiologie appliquée à l'agroalimentaire, au biomédical et à l'environnement (LAMAABE), ex. complexe biomédical, Imama, bloc C, BP 119, Tlemcen 13000, Algérie.
authors.forename: Lamia
authors.initials: L
authors.lastname: Boublenza
authors.affiliation: Université de Tlemcen, laboratoire de microbiologie appliquée à l'agroalimentaire, au biomédical et à l'environnement (LAMAABE), ex. complexe biomédical, Imama, bloc C, BP 119, Tlemcen 13000, Algérie.
authors.forename: Hafida
authors.initials: H
authors.lastname: Hassaine
authors.affiliation: Université de Tlemcen, laboratoire de microbiologie appliquée à l'agroalimentaire, au biomédical et à l'environnement (LAMAABE), ex. complexe biomédical, Imama, bloc C, BP 119, Tlemcen 13000, Algérie.
authors.forename: Nabila
authors.initials: N
authors.lastname: Masdoua
authors.affiliation: Université de Franche-Comté, UBFC, EA3181, LabEx LipSTIC, 25000 Besançon, France; CHRU de Besançon, laboratoire de biologie cellulaire et moléculaire, Inserm CIC 1431, 25000 Besançon, France.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Prétet
authors.affiliation: Université de Franche-Comté, UBFC, EA3181, LabEx LipSTIC, 25000 Besançon, France; Université Ibn Zohr, Agadir, Maroc.
authors.forename: Essaada
authors.initials: E
authors.lastname: Belglaiaa
authors.affiliation: Université de Franche-Comté, UBFC, EA3181, LabEx LipSTIC, 25000 Besançon, France; CHRU de Besançon, laboratoire de biologie cellulaire et moléculaire, Inserm CIC 1431, 25000 Besançon, France.
authors.forename: Christiane
authors.initials: C
authors.lastname: Mougin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000462:Algeria; D001005:Anus Neoplasms / Q000821:virology*; D004279:DNA, Viral / Q000302:isolation & purification*; D005260:Female; D005833:Genital Neoplasms, Female / Q000821:virology*; D005838:Genotype; D006258:Head and Neck Neoplasms / Q000821:virology*; D052162:Human papillomavirus 16 / Q000235:genetics / Q000302:isolation & purification; D052161:Human papillomavirus 18 / Q000235:genetics / Q000302:isolation & purification; D006801:Humans; D007822:Laryngeal Neoplasms / Q000821:virology; D008297:Male; D008875:Middle Aged; D027383:Papillomaviridae / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification; D012878:Skin Neoplasms / Q000821:virology*; D014067:Tonsillar Neoplasms / Q000821:virology; D002583:Uterine Cervical Neoplasms / Q000821:virology; D014625:Vaginal Neoplasms / Q000821:virology; D014846:Vulvar Neoplasms / Q000821:virology
chemical_list: D004279:DNA, Viral
keywords: Anogenital cancer; Cancers ano-génitaux; Cancers de la peau; Cancers des VADS; Genotyping; Génotypage; HPV; Head and neck cancer; INNO-LiPA; Skin cancer