title: Comparison of Dysfunctional Lens Index and Scheimpflug Lens Densitometry in the Evaluation of Age-Related Nuclear Cataracts.
abstract: OBJECTIVE
  To describe the Dysfunctional Lens Index (DLI) from ray-tracing aberrometry and to test its correlations with logMAR corrected distance visual acuity (CDVA) and lens grading based on the Lens Opacities Classification System III (LOCS III) and the Scheimpflug-based lens density.
  
  
  METHODS
  The DLI was calculated by the i-Trace Visual Functional Analyzer (Tracey Technologies, Houston, TX). Forty eyes of 30 patients with mild to moderate age-related nuclear cataract were included retrospectively. Nuclear opalescence grading was obtained by slit lamp using the LOCS III, and objective lens densitometry was evaluated by Scheimpflug imaging (Pentacam HR; Oculus Optikgeräte GmbH, Wetzlar, Germany). The average density parameter obtained by Scheimpflug imaging of the nucleus lens was considered.
  
  
  RESULTS
  The DLI showed a high negative linear correlation with the LOCS III nuclear opalescence score (r = -0.662; P < .01). The average density of the lens nucleus was positively correlated with the LOCS III nuclear opalescence score (r = 0.682; P < .01). The CDVA had a stronger relationship with the DLI parameter (r = -0.702, P < .01) compared to the average density values (r = 0.630, P < .01).
  
  
  CONCLUSIONS
  The DLI was correlated with the LOCS III nuclear opalescence score and the Scheimpflug-based lens density. The DLI had a stronger correlation with CDVA compared to the LOCS III classification or the Scheimpflug-based lens density. The DLI may improve the preoperative evaluation of nuclear cataract and the monitoring of its progression.
authors.forename: Fernando
authors.initials: F
authors.lastname: Faria-Correia
authors.forename: Isaac
authors.initials: I
authors.lastname: Ramos
authors.forename: Bernardo
authors.initials: B
authors.lastname: Lopes
authors.forename: Tiago
authors.initials: T
authors.lastname: Monteiro
authors.forename: Nuno
authors.initials: N
authors.lastname: Franqueira
authors.forename: Renato
authors.initials: R
authors.lastname: Ambrósio
mesh_terms: D057128:Aberrometry / Q000379:methods; D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000145:classification* / Q000175:diagnosis*; D003720:Densitometry; D005260:Female; D006801:Humans; D007907:Lens Nucleus, Crystalline / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology