title: Recent Advancement in Natural Hyaluronidase Inhibitors.
abstract: The use of natural products for the treatment of disease is one of the oldest cultures exists. Currently, the research of new drugs using natural products shows a poorly explored biodiversity and a great interest of marketing. The enzymatic inhibition by some natural products is investigated among these is the inhibition of hyaluronidase and the consequent reduction of the degradation of hyaluronic acid. So there is a reduction of inflammation and angiogenesis. This study reports the main natural species studied in inhibiting human hyaluronidase that can be the subject of future research for new drugs.
authors.affiliation: Health Sciences Center, Federal University of Paraíba, Campus I, 58051-970, João Pessoa-PB, Brazil. luciana.scotti@gmail.com.
authors.forename: Luciana
authors.initials: L
authors.lastname: Scotti
authors.forename: Rajeev Kumar
authors.initials: RK
authors.lastname: Singla
authors.forename: Hamilton Mitsugu
authors.initials: HM
authors.lastname: Ishiki
authors.forename: Francisco Jaime B
authors.initials: FJ
authors.lastname: Mendonca
authors.forename: Marcelo Sobral
authors.initials: MS
authors.lastname: da Silva
authors.forename: José Maria
authors.initials: JM
authors.lastname: Barbosa Filho
authors.forename: Marcus Tullius
authors.initials: MT
authors.lastname: Scotti
mesh_terms: D001688:Biological Products / Q000494:pharmacology; D055808:Drug Discovery; D004791:Enzyme Inhibitors / Q000494:pharmacology*; D006801:Humans; D006821:Hyaluronoglucosaminidase / Q000037:antagonists & inhibitors*; D010944:Plants / Q000737:chemistry
chemical_list: D001688:Biological Products; D004791:Enzyme Inhibitors; D006821:Hyaluronoglucosaminidase