title: SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY EVALUATION OF RETINAL STRUCTURE IN PATIENTS WITH SUSACS SYNDROME.
abstract: OBJECTIVE
  To report spectral-domain optical coherence tomography (SD-OCT) features in patients diagnosed with Susacs syndrome.
  
  
  METHODS
  Clinical report of two cases.
  
  
  RESULTS
  Spectral-domain optical coherence tomography was performed in two patients diagnosed with Susacs syndrome. Both the patients had normal macular perfusion on fluorescein angiography (FA). However, SD-OCT revealed bilateral, temporal macular atrophy with disorganization and thinning of the retinal layers. The outer plexiform layer showed nodularity and waviness suggestive of ischemic swelling of the bipolar cells.
  
  
  CONCLUSIONS
  Retinal structural changes in Susacs syndrome have not been described earlier. Spectral-domain optical coherence tomography may be more sensitive than fluorescein angiography in detecting microstructural retinal alterations in various layers, especially in apparently perfused retina. These findings may provide an insight into the pathogenesis of Susacs syndrome.
authors.affiliation: Ocular Imaging Research and Reading Center, Stanley M. Truhlsen Eye Institute, University of Nebraska Medical Center, Omaha, Nebraska.
authors.forename: Aniruddha
authors.initials: A
authors.lastname: Agarwal
authors.forename: Mohamed
authors.initials: M
authors.lastname: Soliman
authors.forename: Salman
authors.initials: S
authors.lastname: Sarwar
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Sadiq
authors.forename: Diana V
authors.initials: DV
authors.lastname: Do
authors.forename: Quan Dong
authors.initials: QD
authors.lastname: Nguyen
authors.forename: Yasir Jamal
authors.initials: YJ
authors.lastname: Sepah
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D012164:Retinal Diseases / Q000000981:diagnostic imaging*; D055955:Susac Syndrome / Q000000981:diagnostic imaging*; D041623:Tomography, Optical Coherence / Q000379:methods*; D055815:Young Adult