In vitro antioxidant, antimicrobial, cytotoxic potential of gold and silver nanoparticles prepared using Embelia ribes.
In recent years, the green synthesis of gold (GNPs) and silver (SNPs) nanoparticles has gained great interest among chemists and researchers. The present study reports an eco-friendly, cost-effective, rapid and easy method for the synthesis of gold and silver nanoparticles using the seed extract of Embelia ribes (SEEr) as capping and reducing agent. The synthesised GNPs and SNPs were characterised using the following techniques: UV-vis spectroscopy, DLS, HR-TEM, FT-IR and XRD. The free radical scavenging potential of GNPs and SNPs was measured by DPPH assay and Phosphomolybdenum assay. Further, the antimicrobial activity against two micro-organisms were tested using disc diffusion method and cytotoxicity of GNPs and SNPs was determined against MCF-7 cell lines at different concentrations by MTT assay. Both the GNPs and SNPs prepared from E. ribes comparatively showed promising results thereby proving their clinical importance.
a Department of Chemical Engineering , Alagappa College of Technology, Anna University , Chennai , India.
Manikandan
M
Dhayalan
b Department of Biotechnology , University of Madras , Chennai , India.
Michael Immanuel Jesse
MI
Denison
a Department of Chemical Engineering , Alagappa College of Technology, Anna University , Chennai , India.
Anitha Jegadeeshwari
AJ
L
b Department of Biotechnology , University of Madras , Chennai , India.
Kathiravan
K
Krishnan
a Department of Chemical Engineering , Alagappa College of Technology, Anna University , Chennai , India.
Nagendra Gandhi
NG
N
D000890:Anti-Infective Agents / Q000494:pharmacology*; D000970:Antineoplastic Agents / Q000494:pharmacology*; D000975:Antioxidants / Q000494:pharmacology*; D031645:Embelia / Q000378:metabolism*; D006046:Gold / Q000494:pharmacology; D006801:Humans; D061986:MCF-7 Cells; D053768:Metal Nanoparticles; D010936:Plant Extracts / Q000378:metabolism; D012639:Seeds / Q000378:metabolism; D012834:Silver / Q000494:pharmacology; D017550:Spectroscopy, Fourier Transform Infrared
D000890:Anti-Infective Agents; D000970:Antineoplastic Agents; D000975:Antioxidants; D010936:Plant Extracts; D012834:Silver; D006046:Gold
Embelia ribes; Green synthesis; gold nanoparticles; seed extract; silver nanoparticles