Primary malignant mixed Müllerian tumour (MMMT) of the vagina and review of the literature.
Primary malignant mixed Müllerian tumour (MMMT) of the vagina is a rare entity. We report a case of a 62-year-old woman who presented with a fixed and hard anterior vaginal wall mass with contact bleeding. She proceeded to have an anterior infralevator pelvic exenteration with urethrectomy and anterior vaginectomy, creation of an ileal conduit and bilateral lymph node dissection. Histopathological examination and immunohistochemistry confirmed the diagnosis of primary MMMT of the vagina. The patient was stage IVA at diagnosis. Despite chemotherapy and radiotherapy, she had progressive disease and eventually passed away at the age of 65 years.
KK Women's and Children's Hospital, Singapore, Singapore.
Geetha
G
Visvalingam
KK Women's and Children's Hospital, Singapore, Singapore.
Wai Kheong Ryan
WK
Lee
Tan Tock Seng Hospital, Singapore, Singapore.
Chin Fong
CF
Wong
Department of Gynaecological Oncology, KK Women's and Children's Hospital, KK Hospital, Singapore, Singapore.
Yong Kuei
YK
Lim
D001706:Biopsy; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008875:Middle Aged; D018200:Mixed Tumor, Mullerian / Q000175:diagnosis / Q000601:surgery*; D009367:Neoplasm Staging; D010385:Pelvic Exenteration; D014621:Vagina / Q000473:pathology* / Q000601:surgery; D014625:Vaginal Neoplasms / Q000473:pathology* / Q000601:surgery