Semiology of neglect: An update.
Hemispatial neglect is a common disabling condition following brain damage to the right hemisphere. Generally, it involves behavioral bias directed ipsilaterally to the damaged hemisphere and loss of spatial awareness for the contralesional side. In this syndrome, several clinical subtypes were identified. The objective of this article is to provide a nosological analysis of the recent data from the literature on the different subtypes of neglect (visual, auditory, somatosensory, motor, egocentric, allocentric and representational neglect), associated ipsilesional and contralesional productive manifestations and their anatomical lesion correlates. These different anatomical-clinical subtypes can be associated or dissociated. They reflect the heterogeneity of this unilateral neglect syndrome that cannot be approached or interpreted in a single manner. We propose that these subtypes result from different underlying deficits: exogenous attentional deficit (visual, auditory neglect); representational deficit (personal neglect, representational neglect, hyperschematia); shift of the egocentric reference frame (egocentric neglect); attentional deficit between objects and within objects (allocentric neglect), endogenous attentional deficit (representational neglect) and transsaccadic working memory or spatial remapping deficit (ipsilesional productive manifestations). Taking into account the different facets of the unilateral neglect syndrome should promote the development of more targeted cognitive rehabilitation protocols.
Service de médecine physique et réadaptation, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neuroscience de Lyon, Université́ Lyon 1, France; Plate-forme "Mouvement et Handicap", Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France. Electronic address: gilles.rode@chu-lyon.fr.
G
G
Rode
Département de Psychologie, Université Catholique, Milan, Italy; Laboratoire de Résonance Magnétique, Fondation Don Gnocchi, Milan, Italy.
C
C
Pagliari
Service de médecine physique et réadaptation, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neuroscience de Lyon, Université́ Lyon 1, France; Plate-forme "Mouvement et Handicap", Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France.
L
L
Huchon
Service de médecine physique et réadaptation, Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France; Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neuroscience de Lyon, Université́ Lyon 1, France; Plate-forme "Mouvement et Handicap", Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France.
Y
Y
Rossetti
Inserm UMR-S 1028, CNRS UMR 5292, ImpAct, Centre de Recherche en Neuroscience de Lyon, Université́ Lyon 1, France; Plate-forme "Mouvement et Handicap", Hôpital Henry-Gabrielle, Hospices Civils de Lyon, France.
L
L
Pisella
D001308:Auditory Perceptual Disorders / Q000145:classification / Q000523:psychology; D001927:Brain Diseases / Q000150:complications*; D007839:Functional Laterality; D006801:Humans; D010468:Perceptual Disorders / Q000145:classification* / Q000503:physiopathology / Q000523:psychology*; D011596:Psychomotor Disorders; D013028:Space Perception; D014796:Visual Perception
Allocentric neglect; Egocentric neglect; Extrapersonal neglect; Hemineglect; Motor neglect; Neglect; Personal neglect; Representational neglect; Sensory neglect; Unilateral spatial neglect