Expanded Criteria Donor Kidney Transplantation: Comparative Outcome Evaluation Between Single Versus Double Kidney Transplantation at 8 Years: A Single Center Experience.
Transplantation of kidneys retrieved from expanded criteria donors is one of the options to expand the pool of available grafts, shorten the waiting time and increase the number of kidney transplant recipients. This study was a retrospective assessment of 99 patients who underwent renal transplantation during the period 2007-2015 with kidneys harvested from expanded criteria donors (ECD) as defined by the United Network for Organ Sharing (UNOS) following routine biopsy of all kidneys obtained by Karpinsky Score. They formed two groups: SKT (67 recipients that received a single kidney) and DKT (32 patients that received dual kidney transplant). An analysis of differences of two groups between graft and patient survival and graft function were performed after 8 years of observation. We observed between two groups the following statistical differences: Donor age (P < .001), basal high risk of recipients (P < .05), wait time before transplant (P < .05), recipient age (P < .001) delayed graft function (P < .005) while we observe similar values of donor renal function, outcome in graft and patient survival and graft function in recipients. The transplantation of kidneys obtained from expanded criteria donor, allows increase in the number of kidney transplants and in the respect of values of biopsy score and the donor renal function, showed in single or dual kidney transplantation with similar graft and patient survival.
Department of Nephrology and Transplant Unit, A.O. S. Camillo-Forlanini, Rome, Italy. Electronic address: pdepaolis@scamilloforlanini.rm.it.
P
P
De Paolis
Department of Nephrology and Transplant Unit, A.O. S. Camillo-Forlanini, Rome, Italy.
R
R
Colonnelli
Department of Nephrology and Transplant Unit, A.O. S. Camillo-Forlanini, Rome, Italy.
A
A
Favarò
Department of Nephrology and Transplant Unit, A.O. S. Camillo-Forlanini, Rome, Italy.
F
F
Salem
Department of Emergency, Hospital Galliena, Genova, Italy.
P
P
Vignally
Transplant Surgical Unit, A.O. S. Camillo-Forlanini, Rome, Italy.
C
C
Carriero
Transplant Surgical Unit, A.O. S. Camillo-Forlanini, Rome, Italy.
M
M
Iappelli
Department of Nephrology and Transplant Unit, A.O. S. Camillo-Forlanini, Rome, Italy.
S
S
Di Giulio
D000328:Adult; D000368:Aged; D001706:Biopsy; D051799:Delayed Graft Function; D046148:Donor Selection / Q000145:classification / Q000379:methods*; D005260:Female; D006085:Graft Survival; D006801:Humans; D007668:Kidney / Q000473:pathology; D007674:Kidney Diseases / Q000601:surgery; D016030:Kidney Transplantation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013995:Time; D014019:Tissue Donors / Q000145:classification* / Q000600:supply & distribution; D016896:Treatment Outcome