Convenient synthesis of allenylphosphoryl compounds via Cu-catalysed couplings of P(O)H compounds with propargyl acetates.
A novel Cu-catalysed substitution reaction of propargyl acetates with P(O)H compounds is developed to afford allenylphosphoryl compounds via C-P bond coupling in high yields under mild conditions. A plausible mechanism involving the nucleophilic interception of the Cu-allenylidene intermediates is proposed.
State Key Laboratory of Materials-Oriented Chemical Engineering, College of Chemistry and Chemical Engineering, Nanjing Tech University, Nanjing 210009, China. shenrw@njtech.edu.cn.
Ruwei
R
Shen
Bing
B
Luo
Jianlin
J
Yang
Lixiong
L
Zhang
Li-Biao
LB
Han