[Oral films as perspective dosage form].
Oral films, namely buccal mucoadhesive films and orodispersible films represent innovative formulations for administration of a wide range of drugs. Oral films show many advantageous properties and are intended for systemic drug delivery or for local treatment of the oral mucosa. In both cases, the film represents a thin layer, which could be intended to adhere to the oral mucosa by means of mucoadhesion; or to rapid dissolution and subsequent swallowing without the need of liquid intake, in the case of orodispersible films. Main constitutive excipients are film-forming polymers, which must in the case of mucoadhesive forms remain on the mucosa within the required time interval. Oral films are currently available on the pharmaceutical market and could compete with conventional oral dosage forms in the future.


BACKGROUND
oral cavity oral films buccal mucoadhesive films orodispersible films film-forming polymers.
Veronika
V
Walicová
Jan
J
Gajdziok
D000268:Adhesiveness; D000284:Administration, Oral; D004304:Dosage Forms; D016503:Drug Delivery Systems; D005079:Excipients / Q000008:administration & dosage; D009061:Mouth Mucosa / Q000378:metabolism; D004364:Pharmaceutical Preparations / Q000008:administration & dosage; D011108:Polymers / Q000008:administration & dosage
D004304:Dosage Forms; D005079:Excipients; D004364:Pharmaceutical Preparations; D011108:Polymers