A strategic stakeholder approach for addressing further analysis requests in whole genome sequencing research.
Whole genome sequencing (WGS) can be a cost-effective and efficient means of diagnosis for some children, but it also raises a number of ethical concerns. One such concern is how researchers derive and communicate results from WGS, including future requests for further analysis of stored sequences. The purpose of this paper is to think about what is at stake, and for whom, in any solution that is developed to deal with such requests. To accomplish this task, this paper will utilize stakeholder theory, a common method used in business ethics. Several scenarios that connect stakeholder concerns and WGS will also posited and analyzed. This paper concludes by developing criteria composed of a series of questions that researchers can answer in order to more effectively address requests for further analysis of stored sequences.
Philosophy Department, Saginaw Valley State University, 7400 Bay Rd. University Center, 48710, Saginaw, MI, USA. bradley.thornock@gmail.com.
Bradley Steven O
BS
Thornock
D001291:Attitude of Health Personnel; D030541:Databases, Genetic; D036281:Genetic Research / Q000941:ethics; D015894:Genome, Human; D006801:Humans; D007258:Informed Consent; D010372:Pediatrics; D017422:Sequence Analysis, DNA; D014342:Truth Disclosure