A Large Institutional Study on Outcomes and Complications after Transcatheter Closure of a Perimembranous-Type Ventricular Septal Defect in 890 Cases.
OBJECTIVE
To investigate the incidence, cause, and prevention of complications associated with interventional therapy for perimembranous ventricular septal defects (pmVSDs).


METHODS
A retrospective analysis was performed on 890 patients with pmVSDs after interventional therapy. The complications were then analyzed by electrocardiography and echocardiography during or after interventional therapy. During the follow-up period of 12-52 (mean of 26.9 ± 21.6) months, the technical success rate was 97.9% (871/890).


RESULTS
The incidence of serious complication was 1.12% (10/890), including five cases of third-degree atrioventricular block, two of severe tricuspid valve regurgitation, one of cerebral infarction in the basal ganglia area, and two of femoral artery thrombosis. No death was reported during patient follow-up.


CONCLUSIONS
Transcatheter closure of pmVSDs in selected patients was found to be effective and safe.


BACKGROUND
Complication; Interventional therapy; Ventricular septal defect.
Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050031, China.
Jun
J
Liu
Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050031, China.
Zhen
Z
Wang
Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050031, China.
Lei
L
Gao
Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050031, China.
Hui-Lian
HL
Tan
Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050031, China.
Qinghou
Q
Zheng
Department of Cardiology, The First Affiliated Hospital of Hebei Medical University, Shijiazhuang, Hebei Province 050031, China.
Mi-Lin
ML
Zhang