Androgen Receptor Antagonists Suppress Immunotherapy in Prostate Cancer.
Surgical castration synergizes with immunotherapy, but chemical castration has suppressive effects.
D000726:Androgen Antagonists / Q000494:pharmacology / Q000627:therapeutic use*; D006801:Humans; D056747:Immunomodulation / Q000187:drug effects*; D007167:Immunotherapy / Q000379:methods; D008297:Male; D011471:Prostatic Neoplasms / Q000188:drug therapy* / Q000276:immunology / Q000378:metabolism* / Q000473:pathology; D011944:Receptors, Androgen / Q000378:metabolism*; D011963:Receptors, GABA-A / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D016176:T-Lymphocyte Subsets / Q000187:drug effects / Q000276:immunology / Q000378:metabolism
D000726:Androgen Antagonists; D011944:Receptors, Androgen; D011963:Receptors, GABA-A