Ru(II)-Catalyzed Direct C(sp(2))-H Activation/Selenylation of Arenes with Selenyl Chlorides.
A new ruthenium catalytic system was developed for the construction of a C(sp(2))-Se bond with the assistance of directing groups. This protocol features mild reaction conditions, wider substrate scope, and convenient late-stage selenylation of bioactive molecules.
Department of Medicinal Chemistry, China Pharmaceutical University , Nanjing 210009, China.
Shiqi
S
Shu
CAS Key Laboratory of Receptor Research, and Synthetic Organic & Medicinal Chemistry Laboratory (SOMCL), Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences , Shanghai 201203, China.
Zhoulong
Z
Fan
Department of Medicinal Chemistry, China Pharmaceutical University , Nanjing 210009, China.
Qizheng
Q
Yao
CAS Key Laboratory of Receptor Research, and Synthetic Organic & Medicinal Chemistry Laboratory (SOMCL), Shanghai Institute of Materia Medica (SIMM), Chinese Academy of Sciences , Shanghai 201203, China.
Ao
A
Zhang