Norovirus epidemics caused by new GII.2 chimera viruses in 2012-2014 in Japan.
The new GII.2 variant collected from May 2012-March 2014 consisted of GII.15 and GII.2 genomes, in which the putative recombination points found in the boundary region between ORF1 and ORF2. These findings suggested that the swapping of structural and non-structural proteins is a common mechanism for generating new epidemic variants in nature.
Osaka University, Osaka 565-0871, Japan. Electronic address: kmotomura@biken.osaka-u.ac.jp.
Kazushi
K
Motomura
Osaka University, Osaka 565-0871, Japan.
Michittra
M
Boonchan
National Institute of Health Sciences, Tokyo 158-8501, Japan.
Mamoru
M
Noda
Sakai City Institute of Public Health, Osaka 590-0953, Japan; Hidaka General Hospital, Wakayama 644-0002, Japan.
Tomoyuki
T
Tanaka
Osaka University, Osaka 565-0871, Japan.
Naokazu
N
Takeda
D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D004196:Disease Outbreaks; D062665:Epidemiological Monitoring; D005243:Feces / Q000821:virology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000821:virology; D005838:Genotype; D006801:Humans; D007564:Japan / Q000453:epidemiology; D009030:Mosaicism; D029322:Norovirus / Q000235:genetics* / Q000472:pathogenicity; D010802:Phylogeny; D016865:Reassortant Viruses / Q000235:genetics* / Q000472:pathogenicity; D011995:Recombination, Genetic; D012189:Retrospective Studies
GII.2; New chimera virus; Norovirus