Association of Serum Concentration of Different Trace Elements with Biomarkers of Systemic Oxidant Status in Dairy Cattle.
There has been some recent criticism about the reliability of the assays commonly used to measure oxidant status in cattle, because some recent publications suggested that the concentration of different trace elements influences the results of these assays. The aim of this study was to test the correlation in 502 bovine serum samples between the concentration of several trace elements (Br, Co, Cr, Cu, Fe, I, Mn, Mo, Ni, Se, Sr, V and Zn) and markers of oxidant status (reactive oxygen species (ROS) and total serum antioxidant capacity (SAC)). The Oxidative Stress index (OSi) was also calculated as ROS/SAC. Some significant correlations were found, although weak (|ρ| < 0.50). Therefore, the relationships observed might be attributed to the different pro- and antioxidant effect of the different elements rather than to the assays detecting these elements instead of the oxidised molecules or total antioxidant potential, respectively. The OSi was poorly correlated (|ρ| ≤ 0.36) with the concentration of the studied trace elements, and therefore, its use is recommended to assess shifts in the systemic redox balance.
Graham Centre for Agricultural Innovation, School of Animal and Veterinary Sciences, Charles Sturt University and NSW Department of Primary Industries, Wagga Wagga, NSW, 2678, Australia. aabuelo@csu.edu.au.|Departamento de Patología Animal, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002, Lugo, Spain. aabuelo@csu.edu.au.
Angel
A
Abuelo
Departamento de Patología Animal, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002, Lugo, Spain.
Joaquín
J
Hernandez
Graham Centre for Agricultural Innovation, School of Animal and Veterinary Sciences, Charles Sturt University and NSW Department of Primary Industries, Wagga Wagga, NSW, 2678, Australia.|Departamento de Patología Animal, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002, Lugo, Spain.
Víctor
V
Alves-Nores
Departamento de Patología Animal, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002, Lugo, Spain.
José L
JL
Benedito
Departamento de Patología Animal, Facultad de Veterinaria, Universidade de Santiago de Compostela, 27002, Lugo, Spain.
Cristina
C
Castillo
D000818:Animals; D000975:Antioxidants / Q000378:metabolism*; D015415:Biomarkers / Q000097:blood; D002417:Cattle; D005260:Female; D008670:Metals / Q000097:blood*; D016877:Oxidants / Q000097:blood*; D018384:Oxidative Stress; D017382:Reactive Oxygen Species / Q000097:blood*; D014131:Trace Elements / Q000097:blood*
D000975:Antioxidants; D015415:Biomarkers; D008670:Metals; D016877:Oxidants; D017382:Reactive Oxygen Species; D014131:Trace Elements
Antioxidants; Metabolic stress; Oxidative Stress index; Oxidative stress; Redox balance