Robust power spectral estimation for EEG data.
Typical electroencephalogram (EEG) recordings often contain substantial artifact. These artifacts, often large and intermittent, can interfere with quantification of the EEG via its power spectrum. To reduce the impact of artifact, EEG records are typically cleaned by a preprocessing stage that removes individual segments or components of the recording. However, such preprocessing can introduce bias, discard available signal, and be labor-intensive. With this motivation, we present a method that uses robust statistics to reduce dependence on preprocessing by minimizing the effect of large intermittent outliers on the spectral estimates.



Using the multitaper method (Thomson, 1982) as a starting point, we replaced the final step of the standard power spectrum calculation with a quantile-based estimator, and the Jackknife approach to confidence intervals with a Bayesian approach. The method is implemented in provided MATLAB modules, which extend the widely used Chronux toolbox.



Using both simulated and human data, we show that in the presence of large intermittent outliers, the robust method produces improved estimates of the power spectrum, and that the Bayesian confidence intervals yield close-to-veridical coverage factors.



The robust method, as compared to the standard method, is less affected by artifact: inclusion of outliers produces fewer changes in the shape of the power spectrum as well as in the coverage factor.



In the presence of large intermittent outliers, the robust method can reduce dependence on data preprocessing as compared to standard methods of spectral estimation.
Tri-Institutional Program in Computational Biology in Medicine, Weill Cornell Medical College, 1300 York Avenue, Box 194, New York, NY 10065, United States. Electronic address: tam2022@med.cornell.edu.
Tamar
T
Melman
Feil Family Brain and Mind Research Institute and Department of Neurology, Weill Cornell Medical College, 1300 York Avenue, New York, NY 10021, United States. Electronic address: jdvicto@med.cornell.edu.
Jonathan D
JD
Victor
D016477:Artifacts; D001499:Bayes Theorem; D001767:Blinking; D001921:Brain / Q000502:physiology; D003198:Computer Simulation; D003627:Data Interpretation, Statistical; D004569:Electroencephalography / Q000379:methods*; D006801:Humans; D008297:Male; D008959:Models, Neurological; D012815:Signal Processing, Computer-Assisted; D012984:Software; D055815:Young Adult
Bayesian confidence interval estimation; Fourier decomposition; Multitaper method; Order statistics; Spectral analysis