[Prevention and management of anterior resection syndrome].
Because of the improvement of surgical technique and the widely use of multimodality therapy, more patients with rectal cancer undergo sphincter-preserving surgery. However, it has been reported that up to 90% of such patients will suffer from bowel dysfunction, ranging from increased bowel frequency to faecal incontinence or evacuatory dysfunction. This wide spectrum of symptoms after resection of the rectum has been termed anterior resection syndrome (ARS). This disordered bowel function has a substantial negative effect on quality of life, however, the causal mechanisms have not been clarified. The present review discusses the clinical manifestation, underlying mechanisms, as well as prevention and treatment strategies.
Department of Colorectal Cancer Surgery, Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University Cancer Hospital and Institute, Beijing 100142, China. zlgujin@126.com.
Jin
J
Gu
Hongda
H
Pan
D003131:Combined Modality Therapy; D013505:Digestive System Surgical Procedures / Q000009:adverse effects*; D005242:Fecal Incontinence; D006801:Humans; D059351:Organ Sparing Treatments; D011183:Postoperative Complications / Q000517:prevention & control* / Q000628:therapy*; D011788:Quality of Life; D012004:Rectal Neoplasms / Q000601:surgery*; D012007:Rectum / Q000503:physiopathology*