Comparison of Anthropometric and Atherogenic Indices as Screening Tools of Metabolic Syndrome in the Kazakh Adult Population in Xinjiang.
OBJECTIVE
To compare the screening ability of various anthropometric and atherogenic indices for Metabolic syndrome (MetS) using three common criteria and to evaluate the validity of suitable parameters in combination for the screening of MetS among a Kazakh population in Xinjiang.


METHODS
A total of 3752 individuals were selected using the stratified cluster random sampling method from nomadic Kazakhs (≥18 years old) in Xinyuan county, Xinjiang, China, which is approximately 4407 km away from the capital Beijing. MetS was defined by the International Diabetes Federation (IDF), National Cholesterol Education Program Adult Treatment Panel III (ATP III) and Joint Interim Statement (JIS) criteria. The receiver operating characteristic curve (ROC) was used to compare the area under the ROC curve (AUC) of each index. The sensitivity, specificity, Youden's index and cut-offs of each index for the screening of MetS were calculated.


RESULTS
According to the IDF, ATP III and JIS criteria, 18.61%, 10.51%, and 24.83% of males and 23.25%, 14.88%, and 25.33% of females had MetS. According to the IDF criteria, the waist-to-height ratio (WHtR) was the index that most accurately identified individuals with and without MetS both in males (AUC = 0.872) and females (AUC = 0.804), with the optimal cut-offs of 0.53 and 0.52, respectively. According to both the ATP III and JIS criteria, the lipid accumulation product (LAP) was the best index to discriminate between individuals with and without MetS in males (AUC = 0.856 and 0.816, respectively) and females (AUC = 0.832 and 0.788, respectively), with optimal cut-offs of 41.21 and 34.76 in males and 28.16 and 26.49 in females, respectively. On the basis of the IDF standard, Youden's indices of WHtR and LAP serial tests for the screening of MetS were 0.590 and 0.455 in males and females, respectively, and those of WHtR and LAP parallel tests were 0.608 and 0.479, accordingly.


CONCLUSIONS
According to the IDF, ATP III and JIS criteria, both the WHtR and LAP were better indices for the screening of MetS. The WHtR and LAP parallel test was the most accurate.
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. 18999335467@163.com.
Xiang-Hui
XH
Zhang
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. zmberry@foxmail.com.
Mei
M
Zhang
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. hejia123.shihezi@163.com.
Jia
J
He
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. erniu19880215@sina.com.
Yi-Zhong
YZ
Yan
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. jiaojiaolong881202@163.com.
Jiao-Long
JL
Ma
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. kwang311@hotmail.com.
Kui
K
Wang
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. marulin@126.com.
Ru-Lin
RL
Ma
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. guoheng@shzu.edu.cn.
Heng
H
Guo
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. murat08123@163.com.
La-Ti
LT
Mu
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. 13399931625@163.com.
Yu-Song
YS
Ding
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. yfyxxzjy@126.com.
Jing-Yu
JY
Zhang
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. liujiaming@shzu.edu.cn.
Jia-Ming
JM
Liu
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. lishugang@ymail.com.
Shu-Gang
SG
Li
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. niuqiang1214@163.com.
Qiang
Q
Niu
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. ruidongsheng@gmail.com.
Dong-Sheng
DS
Rui
Department of Public Health, Shihezi University School of Medicine, Shihezi 832000, China. gsxshzu@sina.com.|Department of Pathology and Key Laboratory of Xinjiang Endemic and Ethnic Diseases, Ministry of Education, Shihezi University School of Medicine, Shihezi 832000, China. gsxshzu@sina.com.
Shu-Xia
SX
Guo
D000328:Adult; D019540:Area Under Curve; D050197:Atherosclerosis / Q000175:diagnosis* / Q000503:physiopathology; D001823:Body Composition; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000295:instrumentation* / Q000379:methods; D024821:Metabolic Syndrome / Q000175:diagnosis* / Q000453:epidemiology / Q000503:physiopathology; D012372:ROC Curve; D015203:Reproducibility of Results; D065927:Waist-Height Ratio
Kazakh; anthropometric indices; atherogenic indices; metabolic syndrome; screening