Brain Multimodality Monitoring: Updated Perspectives.
The challenges posed by acute brain injury (ABI) involve the management of the initial insult in addition to downstream inflammation, edema, and ischemia that can result in secondary brain injury (SBI). SBI is often subclinical, but can be detected through physiologic changes. These changes serve as a surrogate for tissue injury/cell death and are captured by parameters measured by various monitors that measure intracranial pressure (ICP), cerebral blood flow (CBF), brain tissue oxygenation (PbtO2), cerebral metabolism, and electrocortical activity. In the ideal setting, multimodality monitoring (MMM) integrates these neurological monitoring parameters with traditional hemodynamic monitoring and the physical exam, presenting the information needed to clinicians who can intervene before irreversible damage occurs. There are now consensus guidelines on the utilization of MMM, and there continue to be new advances and questions regarding its use. In this review, we examine these recommendations, recent evidence for MMM, and future directions for MMM.
Department of Neurology and Neurocritical Care, Columbia University, 177 Fort Washington Ave, New York, NY, 10032, USA.
David
D
Roh
Department of Neurology and Neurocritical Care, Columbia University, 177 Fort Washington Ave, New York, NY, 10032, USA. sp3291@cumc.columbia.edu.
Soojin
S
Park
D001921:Brain / Q000503:physiopathology*; D001927:Brain Diseases / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000503:physiopathology; D002560:Cerebrovascular Circulation / Q000502:physiology; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology; D008991:Monitoring, Physiologic; D064847:Multimodal Imaging
Brain metabolism; Brain tissue oxygenation; Cerebral blood flow; Intracranial pressure; Microdialysis; Multimodal monitoring