[Application of perfusion of low molecular dextran via splenic artery in portal azygous devascularization for portal hypertension].
OBJECTIVE
To evaluate the effects of the perfusion of low molecular dextran via the splenic artery in portal azygous devascularization for portal hypertension in the prevention from portal vein thrombosis.


METHODS
A total of 92 patients with portal hypertension were randomly divided into a control group (46 cases) that received the extensive devascularization around the cardia, and a trial group (46 cases) that received the above-mentioned operation and the perfusion of low molecular dextran via the splenic artery. The incidence of portal vein thrombus after the operation and the preoperative and postoperative blood transfusion were observed and the results were analyzed and compared between the two groups.


RESULTS
The incidence of thrombosis and blood transfusion were 26.1% (12/46) and CRBC 4~6 U respectively in the control group, while those were 4.3% (2/46) and CRBC 2~3 U respectively in the trial group. The differences were statistically significant (P < 0.05).


CONCLUSIONS
The perfusion of low molecular dextran via the splenic artery in portal azygous devascularization for portal hypertension is effective and safe in the prevention from portal vein thrombosis.
Li-jun
LJ
Liu
Wei
W
Yu
Yong-jun
YJ
Kuang
D000293:Adolescent; D000328:Adult; D000368:Aged; D003911:Dextrans / Q000008:administration & dosage* / Q000737:chemistry; D005260:Female; D006801:Humans; D006975:Hypertension, Portal / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D011169:Portal Vein / Q000601:surgery; D011183:Postoperative Complications / Q000188:drug therapy* / Q000209:etiology; D013156:Splenectomy / Q000009:adverse effects; D013157:Splenic Artery / Q000187:drug effects; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control*; D055815:Young Adult
D003911:Dextrans