Impact of Gender on Outcome in Octogenarians after Coronary Artery Bypass Grafting.
BackgroundIncreasing life expectancy makes cardiac surgery in octogenarians not very uncommon. In this study, the impact of gender on outcome of octogenarians after coronary artery bypass grafting (CABG) was assessed.Materials and MethodsWe retrospectively studied 485 octogenarians (176 females: mean age 82.4 ± 2.2 years vs. 306 males: mean age 82.2 ± 2.4 years) who underwent isolated CABG using extracorporeal circulation between January 2005 and December 2012.ResultsNo significant differences were noted between both gender groups with regard to preoperative risk factors. At baseline, the groups differed significantly with respect to mean logistic European System for Cardiac Operative Risk Evaluation (EuroSCORE) (women: 22.3 ± 17.4% vs. men: 17.5 ± 13.3%;p< 0.001). Likewise, EuroSCORE II differs significantly between women and men in our cohort (women: 16.7 ± 11.9% vs. men: 13.9 ± 10.7%;p= 0.008). Intraoperatively, the number of distal anastomoses (3.1 ± 0.9 vs. 3.2 ± 0.8), the mean extracorporeal circulation time (99 ± 31 vs. 102 ± 29 minutes), and the mean aortic cross-clamp time (63 ± 31 vs. 60 ± 19 minutes) were similar in both groups. Postoperatively, no significant differences in complications and major morbidity were observed between the groups. The 30-day mortality (women 8.0 vs. men 9.7%;p= 0.62) were without statistical significance between the groups.ConclusionOutcome of octogenarians after CABG resulted in acceptable mortality. Female gender was not associated with increased risks for morbidity and mortality after surgery. Satisfactory outcomes encourage the offering of surgery in octogenarians.
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Rouven
R
Berndt
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Bernd
B
Panholzer
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Katharina
K
Huenges
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Jill
J
Jussli-Melchers
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Felix
F
Schoeneich
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Christine
C
Friedrich
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Grischa
G
Hoffmann
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Jochen
J
Cremer
Department of Cardiovascular Surgery, University of Schleswig-Holstein, Kiel, Germany.
Assad
A
Haneya
D000367:Age Factors; D000369:Aged, 80 and over; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000401:mortality; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D005260:Female; D005858:Germany; D006801:Humans; D053208:Kaplan-Meier Estimate; D008297:Male; D018579:Patient Selection; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome