Occult gastric cancer with distant metastasis proven by random gastric biopsy.
Krukenberg tumor, a rare metastatic ovarian tumor arising from gastrointestinal adenocarcinoma mainly, tends to occur in premenopausal females. Finding the origin of a Krukenberg tumor is crucial for determining prognosis. In Eastern countries, the most common origin of Krukenberg tumor is stomach cancer, which is generally diagnosed via endoscopic biopsy to investigate an abnormal mucosal lesion. Here, we describe a case of huge adnexal mass in a 33-year-old woman who presented with abdominal distension. Two independent endoscopic examinations performed by experts in two tertiary university hospitals revealed no abnormal mucosal lesion. The patient was diagnosed with a Krukenberg tumor according to findings from random endoscopic biopsies taken from normal-looking gastric mucosa in our hospital. It is very rare to be diagnosed via a random biopsy in cases where three well-trained endoscopists had not found any mucosal lesion previously. Thus, in this case, random biopsy was helpful in finding the origin of a Krukenberg tumor.
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Sang Hyuk
SH
Lee
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Kyu-Hyoung
KH
Lim
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Seo-Young
SY
Song
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Hui-Young
HY
Lee
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Sung Chul
SC
Park
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Chang Don
CD
Kang
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Sung Joon
SJ
Lee
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Dong Wook
DW
Choi
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Sung Bae
SB
Park
Sang Hyuk Lee, Kyu-Hyoung Lim, Seo-Young Song, Hui-Young Lee, Sung Chul Park, Chang Don Kang, Sung Joon Lee, Dong Wook Choi, Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon 24341, South Korea.
Young-Joon
YJ
Ryu
D000328:Adult; D001706:Biopsy; D003113:Colonoscopy; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D005773:Gastroscopy; D006801:Humans; D007725:Krukenberg Tumor / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D010051:Ovarian Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000556:secondary*; D000072078:Positron Emission Tomography Computed Tomography; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000473:pathology*; D016896:Treatment Outcome; D051598:Whole Body Imaging / Q000379:methods
Biopsy; Diagnosis; Endoscopy; Gastric cancer; Krukenberg tumor