Preparation of a novel positively charged nanofiltration composite membrane incorporated with silver nanoparticles for pharmaceuticals and personal care product rejection and antibacterial properties.
A novel positively charged N-[(2-hydroxy-3-trimethylammonium)propyl] chloride chitosan (HTCC)-Ag/polyethersulfone (PES) composite nanofiltration membrane was easily prepared by coating the active layer, HTCC, onto PES as the support through epichlorohydrin as the cross-linking reagent and nano-Ag particles as the introduced inorganic components. Scanning election microscopy, X-ray photoelectron spectroscopy, atomic force microscopy, and X-ray diffraction were employed to characterize the morphology of the resultant membranes, of which the molecular weight cut-off was about 941 Da. At 25 °C, the pure water permeability is 16.27 L/h·m(2)·MPa. Our results showed that the rejection of pharmaceuticals and personal care products (PPCPs) followed the sequence: atenolol > carbamazepine > ibuprofen, confirming that the membranes were positively charged. The antibacterial properties of the membranes were compared to elucidate the existence of Ag nanoparticles which help to improve antibacterial activity against Gram-negative Escherichia coli (DH5α, Rosetta) and Gram-positive Bacillus subtilis. The inhibition zone diameters of HTCC-Ag/PES membranes towards E. coli DH5α, E. coli Rosetta and Bacillus subtilis were 17.77, 16.18, and 15.44 mm, respectively. It was found that HTCC-Ag/PES membrane has a better antibacterial activity against E. coli than against Bacillus subtilis, especially for E. coli DH5α.
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China E-mail: hzhlqfox@njust.edu.cn.
Zhong-Hua
ZH
Huang
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China E-mail: hzhlqfox@njust.edu.cn.
Yan-Na
YN
Yin
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China E-mail: hzhlqfox@njust.edu.cn.
Gu-li-mi-la
GL
Aikebaier
School of Environmental and Biological Engineering, Nanjing University of Science and Technology, Nanjing 210094, China E-mail: hzhlqfox@njust.edu.cn.
Yan
Y
Zhang
D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001412:Bacillus subtilis / Q000187:drug effects; D048271:Chitosan / Q000737:chemistry; D003432:Cross-Linking Reagents; D004926:Escherichia coli / Q000187:drug effects; D005374:Filtration / Q000295:instrumentation*; D008567:Membranes, Artificial; D053768:Metal Nanoparticles / Q000737:chemistry*; D010539:Permeability; D004364:Pharmaceutical Preparations / Q000737:chemistry*; D056951:Photoelectron Spectroscopy; D011108:Polymers; D012834:Silver / Q000737:chemistry*; D013450:Sulfones; D014874:Water Pollutants, Chemical / Q000737:chemistry*; D014961:X-Ray Diffraction
D000900:Anti-Bacterial Agents; D003432:Cross-Linking Reagents; D008567:Membranes, Artificial; D004364:Pharmaceutical Preparations; D011108:Polymers; D013450:Sulfones; D014874:Water Pollutants, Chemical; C022840:polyether sulfone; D012834:Silver; D048271:Chitosan