Hyponatremia and Hepatorenal Syndrome.
Hyponatremia and hepatorenal syndrome are severe complications in patients with cirrhosis and ascites resulting from circulatory abnormalities (splanchnic and systemic vasodilatation) that develop with portal hypertension. Both conditions are associated with an increased risk of death. Hyponatremia and renal failure may develop in patients with cirrhosis due to causes other than portal hypertension. Making an accurate differential diagnosis is important both therapeutically and prognostically. In this article, we discuss the pathophysiology, diagnosis, differential diagnosis, and management of hyponatremia and hepatorenal syndrome in patients with cirrhosis.
Dr Mohanty is a clinical fellow in the Section of Digestive Diseases at Yale University School of Medicine in New Haven, Connecticut and is affiliated with the Section of Digestive Diseases at the Veterans Administration-Connecticut Health Care System in West Haven, Connecticut. Dr Garcia-Tsao is a professor of medicine in the Section of Digestive Diseases at Yale University School of Medicine and is the chief of the Section of Digestive Diseases at the Veterans Administration-Connecticut Health Care System.
Arpan
A
Mohanty
Dr Mohanty is a clinical fellow in the Section of Digestive Diseases at Yale University School of Medicine in New Haven, Connecticut and is affiliated with the Section of Digestive Diseases at the Veterans Administration-Connecticut Health Care System in West Haven, Connecticut. Dr Garcia-Tsao is a professor of medicine in the Section of Digestive Diseases at Yale University School of Medicine and is the chief of the Section of Digestive Diseases at the Veterans Administration-Connecticut Health Care System.
Guadalupe
G
Garcia-Tsao
Hyponatremia; ascites; cirrhosis; hepatorenal syndrome