Living Donor Lung Transplantation for Pleuroparenchymal Fibroelastosis.
We report the first patient with pleuroparenchymal fibroelastosis (PPFE) to undergo living donor bilateral lobar lung transplantation. The patient was diagnosed with secondary PPFE as a late complication of chemotherapy that included high-dose cyclophosphamide for mature B-cell lymphocytic leukemia. Although the patient maintained complete remission, dry cough and back pain appeared 8 years after the chemotherapy. He had repeated bilateral pneumothoraces, and his respiratory condition gradually deteriorated because of progressive pleural thickening and parenchymal fibrosis. He underwent living-donor bilateral lobar lung transplantation with an inverse transplant on the left side.
Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Atsushi
A
Hata
Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan. Electronic address: takahiro_nakajima@med.miyazaki-u.ac.jp.
Takahiro
T
Nakajima
Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Shigetoshi
S
Yoshida
Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Taku
T
Kinoshita
Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Jiro
J
Terada
Department of Respirology, Graduate School of Medicine, Chiba University, Chiba, Japan.
Koichiro
K
Tatsumi
Department of Cardiovascular Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Goro
G
Matsumiya
Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Hiroshi
H
Date
Department of General Thoracic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.
Ichiro
I
Yoshino
D000328:Adult; D000970:Antineoplastic Agents / Q000009:adverse effects*; D006801:Humans; D015448:Leukemia, B-Cell / Q000188:drug therapy*; D019520:Living Donors; D016040:Lung Transplantation; D008297:Male; D010995:Pleural Diseases / Q000601:surgery*; D011658:Pulmonary Fibrosis / Q000601:surgery*
D000970:Antineoplastic Agents