[Zinc homeostasis and indicators of muscle activity in experimental graduated exercise on the background of zinc asparaginate].
The influence of a regular (for 7 and 14 days) 10-minute dosed exercise in isolation and on the background of intragastric administration of 5 and 15 mg/kg of zinc (II) asparaginate on the distribution of this metal in the organs and tissues of experimental animals and the indicators of muscle activity such as the level of lactate, creatinine and creatine kinase (EC 2.7.3.2.) serum were studied. It has been shown that exercise stress for 14 days causes a more pronounced change in homeostasis Zn, compared with 7 day, it is reflected in increased levels in the kidney, serum, liver, skeletal muscle and fur animals. It has been shown that graduated exercise for 14 days causes a more pronounced change in Zn homeostasis, compared with 7 day that expressed in increased its levels in the kidney, serum, liver, skeletal muscle and fur animals. Introduction zinc (II) asparaginate accompanied by an increase of its content in the liver, kidneys, hair and serum, but not skeletal and cardiac muscle. The combination of physical activity and the introduction of zinc positive effect on homeostasis of Zn, and the terms of muscle activity. The protective effect of zinc asparaginate with graduated exercise in the experiment was concluded.
A A
AA
Skalny
A A
AA
Tinkov
Yu S
YS
Medvedeva
I B
IB
Alchinova
E Yu
EY
Bonitenko
M Yu
MY
Karganov
A A
AA
Nikonorov
D000818:Animals; D001216:Asparagine / Q000494:pharmacology*; D006706:Homeostasis / Q000187:drug effects*; D008297:Male; D018482:Muscle, Skeletal / Q000378:metabolism*; D010805:Physical Conditioning, Animal; D051381:Rats; D017208:Rats, Wistar; D015032:Zinc / Q000378:metabolism* / Q000494:pharmacology*
D001216:Asparagine; D015032:Zinc