Relationship between mean platelet volume and central serous chorioretinopathy.
The aim of this study was to investigate the mean platelet volume (MPV) of patients with central serous chorioretinopathy (CSCR). Thirty patients were included in the study. Thirty healthy volunteers were recruited as the control group. All patients and control subjects underwent complete ocular examination. Hemoglobin, hematocrit, white blood cell, neutrophil, lymphocyte, platelet count, and MPV of the participants were recorded. Data of patients with CSCR were compared with the control subjects. Patients with CSCR had significantly higher MPV values (9.76 ± 1.36 fL) compared with the control subjects (8.37 ± 0.72 fL) (p = 0.004). No significant difference was found in platelet counts between the CSCR group and the control group (259 ± 53.75 and 243 ± 52.11 K/Ul, p = 0.253). According to the receiver operator characteristics curve analysis, the optimal cut-off value of MPV to predict the CSCR was >9.4, with 60.0 % sensitivity and 93.3 % specificity. Our results demonstrated that the MPV values were significantly higher in patients with CSCR. MPV may be used as a predictive tool for identifying risk for CSCR.
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey. dursunayhan01@gmail.com.
Ayhan
A
Dursun
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey.
Mustafa Ilker
MI
Toker
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey.
Ayşe Vural
AV
Ozec
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey.
Erman
E
Bozali
Department of Ophthalmology, School of Medicine, Bozok University, Yozgat, Turkey.
Kadir
K
Kirboga
Department of Ophthalmology, Numune Hospital, 58000, Sivas, Turkey.
Feyza Gulac
FG
Dursun
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey.
Haydar
H
Erdogan
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey.
Aysen
A
Topalkara
Department of Ophthalmology, School of Medicine, Cumhuriyet University, 58140, Sivas, Turkey.
Mustafa Kemal
MK
Arici
D000328:Adult; D016022:Case-Control Studies; D056833:Central Serous Chorioretinopathy / Q000097:blood*; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014792:Visual Acuity
Central serous chorioretinopathy; Mean platelet volume