JNK signaling mediates wing form polymorphism in brown planthoppers (Nilaparvata lugens).
Wing polyphenism is considered to be an adaptive trade-off between migration (long winged forms) and reproduction (short winged forms), determined by various environmental conditions. The c-Jun NH2-terminal kinase (JNK) is crucial for the regulation of the activity of a number of transcription factors, and is activated under stress and environmental fluctuations where it functions in maintaining cell viability and proliferation. We used RNA interference and a pharmacological inhibitor of JNK to test the role of JNK signaling in regulating the wing dimorphism of the brown planthopper, Nilaparvata lugens. Silencing NlJNK increased the proportion of short winged female adults, reminiscent of the effect of silencing inhibitory components of the insulin-signaling pathway, such as NlAkt. However, silencing of the JNK-activated transcription factors NlJun and NlFos did not change the wing form ratio significantly, indicating that NlJNK may not act through NlJun and NlFos in mediating this process. In summary, JNK signaling may play a role in determining wing polymorphism in N. lugens females.
College of Life Sciences, China Jiliang University, Hangzhou, 310018, China. Electronic address: linxinda@cjlu.edu.cn.
Xinda
X
Lin
College of Life Sciences, China Jiliang University, Hangzhou, 310018, China.
Yili
Y
Xu
College of Life Sciences, China Jiliang University, Hangzhou, 310018, China.
Yun
Y
Yao
College of Life Sciences, China Jiliang University, Hangzhou, 310018, China.
Bo
B
Wang
Department of Entomology, Washington State University, Pullman, WA, 99164, USA.
Mark D
MD
Lavine
Department of Entomology, Washington State University, Pullman, WA, 99164, USA.
Laura Corley
LC
Lavine
D000818:Animals; D018507:Gene Expression Regulation, Developmental; D006430:Hemiptera / Q000235:genetics* / Q000254:growth & development* / Q000378:metabolism; D019476:Insect Proteins / Q000235:genetics* / Q000378:metabolism; D048031:JNK Mitogen-Activated Protein Kinases / Q000235:genetics* / Q000378:metabolism; D017422:Sequence Analysis, DNA; D015398:Signal Transduction; D014921:Wings, Animal / Q000254:growth & development*
D019476:Insect Proteins; D048031:JNK Mitogen-Activated Protein Kinases
Brown planthopper; FOXO; Fos; JNK signaling; Jun; Polyphenism; Wing