Finding a new role for NEMO: A key player in preventing hepatocyte apoptosis and liver tumorigenesis by inhibiting RIPK1.
Division of Gastroenterology Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
I-Fang
IF
Hsin
Division of Gastroenterology Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
Erica
E
Montano
Division of Gastroenterology Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA.
Ekihiro
E
Seki
D000818:Animals; D017209:Apoptosis / Q000235:genetics* / Q000502:physiology; D063646:Carcinogenesis / Q000235:genetics / Q000473:pathology*; D015972:Gene Expression Regulation, Neoplastic; D022781:Hepatocytes / Q000166:cytology / Q000378:metabolism*; D006801:Humans; D047908:Intracellular Signaling Peptides and Proteins / Q000235:genetics / Q000378:metabolism*; D008113:Liver Neoplasms / Q000235:genetics / Q000473:pathology*; D051379:Mice; D018345:Mice, Knockout; D053422:Receptor-Interacting Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism*; D012680:Sensitivity and Specificity; D015398:Signal Transduction
D047908:Intracellular Signaling Peptides and Proteins; C514981:NEMO protein, mouse; D053422:Receptor-Interacting Protein Serine-Threonine Kinases; C506251:Ripk1 protein, mouse