Dynamic Chiral Nanoparticle Assemblies and Specific Chiroplasmonic Analysis of Cancer Cells.
Fabricated Ag@Au core-shell nanoparticle (CS NP) assemblies exhibit pronounced and reverse chiral bisignate plasmonic signals spanning 400 to 580 nm, in comparison to Ag NP assemblies. The time-dependent chiro-optical response of assemblies that shift with shell deposition is systematically recorded. Chiral Ag@Au CS NP assemblies first achieve the special discrimination of circulating tumor cells with HER2 overexpression.
The Key Lab of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Yuan
Y
Zhao
The Key Lab of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Yaxin
Y
Yang
The Key Lab of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Jing
J
Zhao
Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Ping
P
Weng
Wuxi Medical School, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Qingfeng
Q
Pang
The Key Lab of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi, Jiangsu, 214122, P. R. China.
Qijun
Q
Song
D045744:Cell Line, Tumor; D006046:Gold / Q000737:chemistry; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D009369:Neoplasms / Q000378:metabolism* / Q000473:pathology*; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000032:analysis* / Q000378:metabolism; D012834:Silver / Q000737:chemistry
D006046:Gold; D018719:Erb-b2 Receptor Tyrosine Kinases; D012834:Silver; C508053:ERBB2 protein, human
Ag core; cancer cells; chiroplasmonic analysis; dynamic chirality; shell deposition