[Serrated adenomas and carcinomas of the colon].
Approximately 5 - 35 % of colorectal carcinomas arise through serrated carcinogenesis. The precursor of such carcinomas are serrated adenomas, which differ from conventional adenomas morphologically as well as genetically. Herein, we provide a basic overview of serrated lesions of the large intestine with the focus on histological diagnosis and molecular biology.
Alena
A
Chlumská
Petr
P
Martínek
Petr
P
Mukenšnabl
Michael
M
Michal
Michal
M
Zámečník
D000236:Adenoma / Q000473:pathology*; D063646:Carcinogenesis; D002277:Carcinoma / Q000473:pathology*; D003110:Colonic Neoplasms / Q000473:pathology*; D003111:Colonic Polyps / Q000473:pathology*; D006801:Humans
hyperplastic polyp - sessile serrated adenoma - traditional serrated adenoma - serrated carcinoma - serrated carcinogenesis.