Fever and arthralgia as the initial symptoms of primary bone marrow diffuse large B-cell lymphoma: A case report.
Primary bone marrow diffuse large B-cell lymphoma (DLBCL) is rare, and only a few cases have been reported. Fever and arthralgia as the initial symptom are extremely rare; however, awareness must be made of this presentation. The current study describes the clinical and pathological findings of a 41-year-old man affected by fever and arthralgia. Blood tests revealed leukopenia and anemia. Multiple bone marrow biopsies were conducted and confirmed the diagnosis of primary bone marrow DLBCL. Primary bone marrow DLBCL is a rare and frequently misdiagnosed subset of non-Hodgkin's lymphoma. The current case demonstrates that utility of bone marrow biopsy for diagnosis should not be ignored, and that repeated bone marrow punctures in multiple locations may be necessary.
Graduate School, Jining Medical University, Jining, Shandong 272000, P.R. China; Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China.
Saisai
S
Ren
Department of Pediatrics, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China.
Yanling
Y
Tao
Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China.
L U
LU
Jia
Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China.
Panpan
P
Cheng
Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China.
Jilei
J
Zhang
Department of Hematology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272129, P.R. China.
Hao
H
Zhang
arthralgia; bone marrow biopsy; diffuse large B-cell lymphoma; fever