Cp*Co(III)-Catalyzed Dehydrative C-H Allylation of 6-Arylpurines and Aromatic Amides Using Allyl Alcohols in Fluorinated Alcohols.
Cp*Co(III)-catalyzed C-H allylation of various aromatic C-H bonds using allyl alcohols as allylating reagents is described. Improved reaction conditions using fluorinated alcohol solvents afforded efficient directed C-H allylation of 6-arylpurines, benzamides, and a synthetically useful Weinreb amide with good functional group compatibility.
Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.
Youka
Y
Bunno
Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.
Nanami
N
Murakami
Graduate School of Pharmaceutical Sciences, The University of Tokyo , Bunkyo-ku, Tokyo 113-0033, Japan.
Yudai
Y
Suzuki
Graduate School of Pharmaceutical Sciences, The University of Tokyo , Bunkyo-ku, Tokyo 113-0033, Japan.
Motomu
M
Kanai
Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.|ACT-C, Japan Science and Technology Agency, Sapporo 060-0812, Japan.
Tatsuhiko
T
Yoshino
Faculty of Pharmaceutical Sciences, Hokkaido University , Sapporo 060-0812, Japan.|ACT-C, Japan Science and Technology Agency, Sapporo 060-0812, Japan.
Shigeki
S
Matsunaga