[The niche for hematopoietic stem and progenitor cells in bone marrow].
It has been hypothesized that the special microenvironments known as niches in the bone marrow play an essential role in maintaining hematopoietic stem and progenitor cells(HSPCs), and the identification of the HSPC niche has been a subject of long-standing argument. Recent studies identified candidate cells meeting the criteria for HSPC niches and the critical transcription factor of their development and maintenance.
Laboratory of Stem Cell Biology and Developmental Immunology,Graduate School of Frontier Biosciences and Graduate School of Medicine, Osaka University, Japan.
Yoshiki
Y
Omatsu
D000818:Animals; D001853:Bone Marrow / Q000276:immunology*; D002454:Cell Differentiation / Q000276:immunology / Q000502:physiology*; D002465:Cell Movement / Q000276:immunology / Q000502:physiology; D006412:Hematopoietic Stem Cells / Q000166:cytology* / Q000276:immunology; D006801:Humans; D010006:Osteoblasts / Q000166:cytology*; D055153:Stem Cell Niche / Q000276:immunology*