Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report.
An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS treatment parameters were: target volume, 8.8 cm(3); total marginal dose, 24 Gy in 3 fractionations at the 50% isodose line. The patient has been free from seizures since 9 months after GKS, with notable improvement in cognitive outcome. Fractionated GKS could be considered as a safe tool for seizure control and neuropsychological improvement in patients with MTLE.
Department of Neurosurgery, Seoul National University Hospital, Seoul 03080, Korea.; Department of Neurosurgery, Soonchunhyang University Seoul Hospital, Seoul 04401, Korea.
Hye Ran
HR
Park
Department of Neurosurgery, Seoul National University Hospital, Seoul 03080, Korea.
Hyun-Tai
HT
Chung
Department of Neurology, Seoul National University Hospital, Seoul 03080, Korea.
Sang Kun
SK
Lee
Department of Neurosurgery, Seoul National University Hospital, Seoul 03080, Korea.
Dong Gyu
DG
Kim
Department of Neurosurgery, Seoul National University Hospital, Seoul 03080, Korea.
Sun Ha
SH
Paek
Epilepsy; Radiosurgery; Stereotaxic Techniques