Not All Diabetes in Infants is Type 1: A Case Report.
Neonatal diabetes mellitus (NDM), defined as persistent hyperglycemia occurring in the first months of life, is a rare cause of hyperglycemia and is often misdiagnosed as type 1 diabetes mellitus (T1DM). Numerous reports have shown that the successful transition from insulin to sulfonylurea agents can be achieved in up to 90% of patients with NDM. However, most of the reports pertain to infants; the literature is limited regarding treatment of adults with NDM. We present our experience with a patient with permanent NDM, initially misdiagnosed as T1DM, who subsequently was successfully transitioned to oral sulfonylurea therapy after 37 years of insulin dependence.
Department of Endocrinology, Diabetes and Metabolism, Mount Sinai Medical Center, Miami Beach, FL, USA.
Karla M
KM
Arce
Department of Endocrinology, Diabetes and Metabolism, Cleveland Clinic, Cleveland, OH, USA. pantalk@ccf.org.
Kevin M
KM
Pantalone
Neonatal diabetes mellitus; Sodium-glucose cotransporter-2 inhibitor; Sulfonylurea