A survey of synthetic nicotinamide cofactors in enzymatic processes.
Synthetic nicotinamide cofactors are analogues of the natural cofactors used by oxidoreductases as redox intermediates. Their ability to be fine-tuned makes these biomimetics an attractive alternative to the natural cofactors in terms of stability, reactivity, and cost. The following mini-review focuses on the current state of the art of those biomimetics in enzymatic processes.
Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628BL, Delft, The Netherlands. c.e.paul@tudelft.nl.
Caroline E
CE
Paul
Department of Biotechnology, Delft University of Technology, Julianalaan 136, 2628BL, Delft, The Netherlands.
Frank
F
Hollmann
D040761:Biomimetic Materials / Q000737:chemistry*; D032701:Biomimetics; D004138:Dinitrocresols / Q000737:chemistry; D009536:Niacinamide / Q000737:chemistry*; D010084:Oxidation-Reduction; D010088:Oxidoreductases / Q000378:metabolism*
D004138:Dinitrocresols; C024132:4,6-dinitro-o-cresol; D009536:Niacinamide; D010088:Oxidoreductases
Biocatalysis; Biomimetics; Cofactor analogues; Oxidoreductases; Synthetic nicotinamide cofactors; mNADHs