Cannabinoid hyperemesis syndrome and the onset of a manic episode.
Cannabinoid hyperemesis syndrome is a rare, recently described, clinically diagnosed condition that is characterised by a chronic history of cannabis use, cyclic nausea and vomiting, symptomatic relief with hot water bathing, and resolution with cessation of use. We present a case of this syndrome concurrent in a patient with bipolar mania. We suggest that a 3-week period of vomiting in the context of this syndrome contributed to the precipitation of a manic episode by lowering mood stabiliser serum levels, and that this syndrome will have significant consequences for the patient's mental health.
University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
Phillip
http://orcid.org/0000-0002-6245-138X
P
Gregoire
University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
Michael
M
Tau
University of Toronto Faculty of Medicine, Toronto, Ontario, Canada.
David
D
Robertson
D000328:Adult; D000339:Affect / Q000187:drug effects; D018692:Antimanic Agents / Q000097:blood / Q000494:pharmacology; D001714:Bipolar Disorder / Q000150:complications* / Q000188:drug therapy / Q000523:psychology; D002186:Cannabinoids / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008297:Male; D002189:Marijuana Abuse / Q000150:complications*; D009325:Nausea / Q000139:chemically induced / Q000150:complications*; D011247:Pregnancy; D013577:Syndrome; D014839:Vomiting / Q000139:chemically induced / Q000150:complications*
D018692:Antimanic Agents; D002186:Cannabinoids