Fruitful Decades for Canthin-6-ones from 1952 to 2015: Biosynthesis, Chemistry, and Biological Activities.
In this review, more than 60 natural canthin-6-one alkaloids and their structures are considered. The biosynthesis, efficient and classic synthetic approaches, and biological activities of canthin-6-one alkaloids, from 1952 to 2015, are discussed. From an analysis of their structural properties and an investigation of the literature, possible future trends for canthin-6-one alkaloids are proposed. The information reported will be helpful in future research on canthin-6-one alkaloids.
College of Science, Northwest A &amp; F University, Yangling 712100, Shaanxi, China. daijkun@hotmail.com.
Jiangkun
J
Dai
College of Science, Northwest A &amp; F University, Yangling 712100, Shaanxi, China. lnuk@nwsuaf.edu.cn.
Na
N
Li
College of Science, Northwest A &amp; F University, Yangling 712100, Shaanxi, China. wangjunru@nwsuaf.edu.cn.
Junru
J
Wang
EaStCHEM School of Chemistry, The University of Edinburgh, The King's Buildings, David Brewster Road, Edinburgh EH9 3FJ, UK. uwe.schneider@ed.ac.uk.
Uwe
U
Schneider
D000470:Alkaloids / Q000138:chemical synthesis* / Q000737:chemistry / Q000494:pharmacology*; D000890:Anti-Infective Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000893:Anti-Inflammatory Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D000970:Antineoplastic Agents / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology; D002243:Carbolines / Q000737:chemistry; D005638:Fruit / Q000737:chemistry*; D026121:Indole Alkaloids / Q000737:chemistry; D015394:Molecular Structure; D047428:Protein Kinase Inhibitors / Q000138:chemical synthesis / Q000737:chemistry / Q000494:pharmacology
D000470:Alkaloids; D000890:Anti-Infective Agents; D000893:Anti-Inflammatory Agents; D000970:Antineoplastic Agents; D002243:Carbolines; D026121:Indole Alkaloids; D047428:Protein Kinase Inhibitors; C453379:canthin-6-one
biological activities; biosynthesis; canthin-6-one; chemistry