PIDA-I2 mediated direct vicinal difunctionalization of olefins: iodoazidation, iodoetherification and iodoacyloxylation.
Iodinium cation (I(+) or IOAc) was produced from the combination of phenyliodine diacetate (PIDA) and iodine. I(+) facilitated the direct vicinal difunctionalization of olefins to α-azido, α-trideuteriomethoxy, α-2,2,2-trifluoroethoxy and α-acyloxy alkyl iodides via cation-π interaction at room temperature and under transition-metal free conditions.
School of Chemical Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, PO Bhimpur-Padanpur, Via Jatni, District Khurda, Odisha 752050, India. pmal@niser.ac.in.
Tapas Kumar
TK
Achar
School of Chemical Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, PO Bhimpur-Padanpur, Via Jatni, District Khurda, Odisha 752050, India. pmal@niser.ac.in.
Saikat
S
Maiti
School of Chemical Sciences, National Institute of Science Education and Research (NISER) Bhubaneswar, PO Bhimpur-Padanpur, Via Jatni, District Khurda, Odisha 752050, India. pmal@niser.ac.in.
Prasenjit
P
Mal