Autograft Substitutes: Conduits and Processed Nerve Allografts.
Manufactured conduits and allografts are viable alternatives to direct suture repair and nerve autograft. Manufactured tubes should have gaps less than 10 mm, and ideally should be considered as an aid to the coaptation. Processed nerve allograft has utility as a substitute for either conduit or autograft in sensory nerve repairs. There is also a growing body of evidence supporting their utility in major peripheral nerve repairs, gap repairs up to 70 mm in length, as an alternative source of tissue to bolster the diameter of a cable graft, and for the management of neuromas in non-reconstructable injuries.
The Buncke Clinic, 45 Castro Street #121, San Francisco, CA 94114, USA. Electronic address: bauback@drsafa.com.
Bauback
B
Safa
The Buncke Clinic, 45 Castro Street #121, San Francisco, CA 94114, USA.
Gregory
G
Buncke
D064591:Allografts; D064592:Autografts; D001672:Biocompatible Materials; D048091:Guided Tissue Regeneration; D006801:Humans; D009416:Nerve Regeneration; D019635:Neurosurgical Procedures; D059348:Peripheral Nerve Injuries / Q000503:physiopathology / Q000601:surgery*; D010525:Peripheral Nerves / Q000601:surgery / Q000637:transplantation*; D054457:Tissue Scaffolds; D020858:Tissue and Organ Harvesting; D014182:Transplantation, Autologous
D001672:Biocompatible Materials
Allograft; Autograft alternative; Autograft substitute; Conduit; Peripheral nerve injury; Peripheral nerve repair