Pilot Randomized Trial of Collaborative Behavioral Treatment for Chronic Pain and Depression in Persons Living with HIV/AIDS.
In this pilot study, we assessed feasibility and acceptability of a behavior therapy intervention for pain and depressive symptoms in persons living with HIV/AIDS (PLWH). We randomly assigned 23 participants to HIV-PASS (HIV-Pain and Sadness Study) or a health education control arm for 3 months. On average, participants attended more than 5 sessions (of 7 possible) in both arms. Qualitative data suggest HIV-PASS participants understood key messages and made concrete behavioral changes. HIV-PASS was associated with effects in the expected direction for three of four outcomes, including the primary outcome (pain-related interference with functioning). Findings suggest that HIV-PASS is promising.
Butler Hospital, 345 Blackstone Boulevard, Providence, RI, 02906, USA. luebelacker@butler.org.|Alpert Medical School of Brown University, Providence, RI, USA. luebelacker@butler.org.
Lisa A
LA
Uebelacker
Alpert Medical School of Brown University, Providence, RI, USA.|Boston VA Healthcare System, Boston, MA, USA.
Risa B
RB
Weisberg
Butler Hospital, 345 Blackstone Boulevard, Providence, RI, 02906, USA.|Alpert Medical School of Brown University, Providence, RI, USA.
Debra S
DS
Herman
Alpert Medical School of Brown University, Providence, RI, USA.|Stanley Street Treatment and Resources, Fall River, MA, USA.
Genie L
GL
Bailey
Alpert Medical School of Brown University, Providence, RI, USA.|The Miriam Hospital, Providence, RI, USA.
Megan M
MM
Pinkston-Camp
Butler Hospital, 345 Blackstone Boulevard, Providence, RI, 02906, USA.|Alpert Medical School of Brown University, Providence, RI, USA.
Sarah L
SL
Garnaat
Alpert Medical School of Brown University, Providence, RI, USA.|The Miriam Hospital, Providence, RI, USA.
Michael D
MD
Stein
D000163:Acquired Immunodeficiency Syndrome / Q000150:complications; D000328:Adult; D001521:Behavior Therapy / Q000379:methods*; D059350:Chronic Pain / Q000523:psychology / Q000628:therapy*; D003863:Depression / Q000175:diagnosis / Q000523:psychology / Q000628:therapy*; D003866:Depressive Disorder; D005260:Female; D015658:HIV Infections / Q000150:complications* / Q000523:psychology; D006266:Health Education; D006801:Humans; D008297:Male; D008875:Middle Aged; D010353:Patient Education as Topic / Q000379:methods; D010865:Pilot Projects; D016896:Treatment Outcome
Behavioral medicine; Chronic pain; Depression; HIV/AIDS