Emergence and Dissemination of ST131 Escherichia coli Isolates Among Patients with Hospital-Acquired Pneumonia in Asian Countries.
We investigated the molecular epidemiology and microbiological characteristics of 51 Escherichia coli isolates causing hospital-acquired pneumonia (HAP) in eight Asian areas. Sequence type 131 (ST131) was the most prevalent among E. coli isolates causing HAP, especially in South Korea, Thailand, and the Philippines. The current study showed that CTX-M-15-producing E. coli ST131 has emerged in and disseminated among patients with HAP in Asia. Our data suggest that this pandemic clone poses an important public health threat even in nosocomial infections.
1 Asia Pacific Foundation for Infectious Diseases (APFID) , Seoul, Republic of Korea.
Min Kyeong
MK
Cha
2 Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
Cheol-In
CI
Kang
1 Asia Pacific Foundation for Infectious Diseases (APFID) , Seoul, Republic of Korea.|2 Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
So Hyun
SH
Kim
3 Department of Medicine, Siriraj Hospital, Mahidol University , Bangkok, Thailand .
Visanu
V
Thamlikitkul
4 SureCare Medical Centre , Kowloon, Hong Kong .
Thomas Man-Kit
TM
So
2 Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
Young Eun
YE
Ha
1 Asia Pacific Foundation for Infectious Diseases (APFID) , Seoul, Republic of Korea.|2 Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
Doo Ryeon
DR
Chung
2 Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
Kyong Ran
KR
Peck
1 Asia Pacific Foundation for Infectious Diseases (APFID) , Seoul, Republic of Korea.|2 Division of Infectious Diseases, Samsung Medical Center, Sungkyunkwan University School of Medicine , Seoul, Republic of Korea.
Jae-Hoon
JH
Song
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D001210:Asia, Southeastern / Q000453:epidemiology; D001211:Asia, Western / Q000453:epidemiology; D003428:Cross Infection / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission; D004269:DNA, Bacterial / Q000235:genetics; D004926:Escherichia coli / Q000187:drug effects / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D004927:Escherichia coli Infections / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission; D006761:Hospitals; D006801:Humans; D058885:Multilocus Sequence Typing; D018410:Pneumonia, Bacterial / Q000453:epidemiology* / Q000382:microbiology / Q000635:transmission; D015995:Prevalence
D000900:Anti-Bacterial Agents; D004269:DNA, Bacterial
ESBL; Escherichia coli; ST131; pneumonia