[Prognostic analysis of CO₂ laser surgery for early glottic cancer with anterior commissure involvement].
OBJECTIVE
To systematically analyze the local recurrence of CO₂ laser surgery for early glottic cancer and without anterior commissure involvement.


METHODS
By searching CBM, CNKI, wanfang, weipu, PubMed, Embase, OVID, and Springer database, the retrospective clinical studies were included according to inclusion and exclusion criteria. Meta analysis of extracted data was carried out by RevMan 5.0 software.


RESULTS
By analyzing the 1900 cases from 14 retrospective studies using Meta analysis, it was indicated that local recurrence rate of AC+ group was significantly higher than that of AC- group [OR = 3.00, 95% CI (2.31, 3.89), P < 0.01] for early glottic cancer. Local recurrence rates between AC+ group and AC- group for glottic cancer of Tis and T₁b stage showed no statistically significant difference, while those for glottic cancer of T₁a and T₂ stage showed statistically significant difference.


CONCLUSIONS
Local recurrence rate of CO₂laser surgery for early glottic cancer was related with anterior commissure involvement.
Suzhen
S
She
Binquan
B
Wang
Ying
Y
Li
Wei
W
Gao
Yan
Y
Feng
D002245:Carbon Dioxide; D016208:Databases, Factual; D005931:Glottis / Q000473:pathology*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000601:surgery*; D053685:Laser Therapy; D009364:Neoplasm Recurrence, Local; D012189:Retrospective Studies
D002245:Carbon Dioxide