Plant GABA:proline ratio modulates dissemination of the virulence Ti plasmid within the Agrobacterium tumefaciens hosted population.
Accumulation of amino acids is a common plant response to several biotic and abiotic stresses, even if the roles of these accumulations remain often poorly understood. In a recent study we measured the levels of different amino acids in tumors of Arabidopsis thaliana induced by the phytopathogen Agrobacterium tumefaciens and correlated these data with changes of gene expressions in both organisms. This led to the demonstration that the non-protein amino acid GABA plays an important role for the adaptation of the bacteria to the plant tumor environment, and especially in the control of the virulent Ti plasmid dissemination. Here we present a model that describes how different GABA:proline ratios in the A. thaliana host may have different impacts on the conjugation of A. tumefaciens Ti plasmid, and advance the view that the amino acid metabolism of plant hosts could be critical for the propagation of the virulence genes in A. tumefaciens populations.
a Institute for Integrative Biology of the Cell (I2BC), CNRS CEA Univ. Paris-Sud, Université Paris-Saclay , Avenue de la Terrasse, Gif-sur-Yvette , France.
Julien
J
Lang
a Institute for Integrative Biology of the Cell (I2BC), CNRS CEA Univ. Paris-Sud, Université Paris-Saclay , Avenue de la Terrasse, Gif-sur-Yvette , France.
Denis
D
Faure
D016960:Agrobacterium tumefaciens / Q000472:pathogenicity*; D017360:Arabidopsis / Q000378:metabolism / Q000382:microbiology*; D001426:Bacterial Proteins / Q000378:metabolism; D001692:Biological Transport; D018698:Glutamic Acid / Q000378:metabolism; D008954:Models, Biological; D036741:Plant Tumor-Inducing Plasmids / Q000378:metabolism*; D010941:Plant Tumors / Q000382:microbiology; D011073:Polyamines / Q000378:metabolism; D011392:Proline / Q000378:metabolism*; D053038:Quorum Sensing; D015398:Signal Transduction; D014774:Virulence; D005680:gamma-Aminobutyric Acid / Q000378:metabolism*
D001426:Bacterial Proteins; D011073:Polyamines; D018698:Glutamic Acid; D005680:gamma-Aminobutyric Acid; D011392:Proline
ABC transporter; Agrobacterium tumefaciens; GABA; lactonase; plant tumor; proline; quorum quenching; quorum sensing