Multiple Chronic Conditions in Older Adults with Acute Coronary Syndromes.
Older adults presenting with acute coronary syndromes (ACSs) often have multiple chronic conditions (MCCs). In addition to traditional cardiovascular (CV) risk factors (ie, hypertension, hyperlipidemia, and diabetes), common CV comorbidities include heart failure, stroke, and atrial fibrillation, whereas prevalent non-CV comorbidities include chronic kidney disease, anemia, depression, and chronic obstructive pulmonary disease. The presence of MCCs affects the presentation (eg, increased frequency of type 2 myocardial infarctions [MIs]), clinical course, and prognosis of ACS in older adults. In general, higher comorbidity burden increases mortality following MI, reduces utilization of ACS treatments, and increases the importance of developing individualized treatment plans.
Department of Cardiology, Linköping University, Linköping, Sweden; Department of Medical and Health Sciences, Linköping University, Linköping, Sweden; Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA.
Joakim
J
Alfredsson
Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: Karen.alexander@duke.edu.
Karen P
KP
Alexander
D054058:Acute Coronary Syndrome / Q000453:epidemiology / Q000628:therapy; D000368:Aged; D015897:Comorbidity; D006801:Humans; D000071069:Multiple Chronic Conditions / Q000453:epidemiology / Q000628:therapy; D009203:Myocardial Infarction / Q000453:epidemiology / Q000628:therapy; D011379:Prognosis; D020379:Risk Adjustment
Acute coronary syndrome; Multiple chronic conditions; Myocardial infarction (MI); Older adults; Type 2 MI