Effects of Pyriproxifen on Aedes japonicus Development and Its Auto-Dissemination by Gravid Females in Laboratory Trials.
In a series of laboratory experiments, we investigated the effects of the juvenile-hormone analog pyriproxyfen on the inhibition of Aedes japonicus adult emergence after exposure of late-stage (3rd/4th) larvae (either field-collected or lab-reared from field-collected eggs) to pyriproxyfen. Emergence inhibition was 74%, 83%, 86%, and 92% at 0.01, 0.5, 2.5, and 5 μg/liter, respectively. Additionally, following a 1-day exposure of larvae to pyriproxyfen-containing water (5 μg/liter), and for a separate cohort exposed to that same water 10 days later, significantly more pupae died resulting in fewer adults emerged in the treatment versus control group. In 4 tent trials, gravid adult females were able to auto-disseminate a 5% pyriproxyfen powder to larval development habitats at high enough concentrations to cause a significant increase in inhibition of adult emergence. Therefore, we conclude that pyriproxyfen has a great potential for use in controlling this invasive cryptic breeder.
1   Institute of Parasitology, National Centre for Vector Entomology, University of Zürich, 8057 Zürich, Switzerland.|2   Present address: NSF Center for Integrated Pest Management, 1730 Varsity Drive, Suite 110, Venture IV Building, Raleigh, NC 27606.
Holly C
HC
Tuten
1   Institute of Parasitology, National Centre for Vector Entomology, University of Zürich, 8057 Zürich, Switzerland.|3   Present address: Institute of Microbiology, ETH Zürich, 8093 Zürich, Switzerland.
Philipp
P
Moosmann
1   Institute of Parasitology, National Centre for Vector Entomology, University of Zürich, 8057 Zürich, Switzerland.
Alexander
A
Mathis
1   Institute of Parasitology, National Centre for Vector Entomology, University of Zürich, 8057 Zürich, Switzerland.|4   Avia-GIS, 2980 Zoersel, Belgium.
Francis
F
Schaffner
D000330:Aedes / Q000187:drug effects*; D000818:Animals; D004305:Dose-Response Relationship, Drug; D005260:Female; D007306:Insecticides / Q000008:administration & dosage / Q000494:pharmacology*; D007814:Larva / Q000187:drug effects / Q000254:growth & development; D011679:Pupa / Q000187:drug effects; D011725:Pyridines / Q000008:administration & dosage / Q000494:pharmacology*; D012098:Reproduction
D007306:Insecticides; D011725:Pyridines; C055613:pyriproxyfen
Aedes japonicus; auto-dissemination; cryptic breeder; juvenile-hormone mimic; mosquito control