Racial Disparities in Corneal Transplantation Rates, Complications, and Outcomes.
Corneal transplantation is a common type of tissue transplantation that aims to improve vision or relieve pain. Given the immune privilege of the cornea, the primary graft often has a high success rate, approaching 90%. Despite the good overall outcome of corneal transplantation in various studies, the individual graft survival rate varies, depending on the preoperative diagnosis and donor and recipient factors. Race and ethnicity have been shown to be important in other types of organ transplantation. The aim of this study was to review the available ophthalmic literature regarding any differences in rates and outcomes of corneal transplantation based on ethnicity and race. A small body of evidence suggests that race might be an important risk factor for graft rejection and graft failure. More robust studies are needed to clarify these associations.
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Jeanie D
JD
Ling
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Viraj
V
Mehta
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Cherie
C
Fathy
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Yuna
Y
Rapoport
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Matthew M
MM
Zhang
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Anthony
A
Daniels
a Vanderbilt Eye Institute, Vanderbilt University Medical Center , Nashville , TN , USA.
Sahar
S
Kohanim
D003316:Corneal Diseases / Q000208:ethnology / Q000601:surgery; D016039:Corneal Transplantation / Q000706:statistics & numerical data*; D005006:Ethnicity; D006084:Graft Rejection / Q000208:ethnology; D054624:Health Status Disparities; D006801:Humans; D044469:Racial Groups / Q000208:ethnology*; D012307:Risk Factors
Corneal transplantation; disparity; keratoplasty; outcomes; race