[Role of non-coding regulatory ribonucleic acids in chronic inflammatory diseases].
Non-coding regulatory ribonucleic acids (RNA), including microRNA, long non-coding RNA and circular RNA, can influence the expression of genes mediating inflammatory processes and therefore affect the course and progression of chronic inflammatory diseases. Recent studies using antisense oligonucleotides suggest that such non-coding regulatory RNAs are suitable as novel therapeutic target molecules for the treatment of inflammatory rheumatic diseases.
Deutsches Rheuma-Forschungszentrum (DRFZ), Charitéplatz 1, 10117, Berlin, Deutschland.
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Heinz
Deutsches Rheuma-Forschungszentrum (DRFZ), Charitéplatz 1, 10117, Berlin, Deutschland. mashreghi@drfz.de.
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Mashreghi
D002908:Chronic Disease; D019317:Evidence-Based Medicine; D006801:Humans; D055261:Immunogenetic Phenomena; D007249:Inflammation / Q000235:genetics* / Q000276:immunology*; D035683:MicroRNAs / Q000235:genetics* / Q000276:immunology*; D022661:RNA, Untranslated / Q000235:genetics* / Q000276:immunology*; D038621:Regulatory Sequences, Ribonucleic Acid / Q000235:genetics / Q000276:immunology
D035683:MicroRNAs; D022661:RNA, Untranslated; D038621:Regulatory Sequences, Ribonucleic Acid
Circular RNA; Inflammation; Long non coding RNA; MicroRNA; Rheumatoid arthritis