Occupational exposures to engine exhausts and other PAHs and breast cancer risk: A population-based case-control study.
Some previous studies have suggested that exposure to engine exhausts may increase risk of breast cancer.



In a population-based case-control study of breast cancer in Western Australia we assessed occupational exposure to engine exhausts using questionnaires and telephone interviews. Odds Ratios (OR) and 95% Confidence Intervals (CI) were calculated using logistic regression.



We found no association between risk of breast cancer and occupational exposure to diesel exhaust (OR 1.07, 95%CI: 0.81-1.41), gasoline exhaust (OR 0.98, 95%CI: 0.74-1.28), or other exhausts (OR 1.08, 95%CI: 0.29-4.08). There were also no significant dose- or duration-response relationships.



This study did not find evidence supporting the association between occupational exposures to engine exhausts and breast cancer risk. Am. J. Ind. Med. 59:437-444, 2016. © 2016 Wiley Periodicals, Inc.
School of Public Health, Curtin University Western Australia, Perth, Western Australia.
Rajni
R
Rai
Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria.
Deborah C
DC
Glass
School of Population Health, The University of Western Australia, Perth, Western Australia.
Jane S
JS
Heyworth
School of Surgery, The University of Western Australia, Perth, Western Australia.
Christobel
C
Saunders
School of Public Health, Curtin University Western Australia, Perth, Western Australia.
Lin
L
Fritschi
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001943:Breast Neoplasms / Q000139:chemically induced*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects* / Q000032:analysis; D016017:Odds Ratio; D010578:Petroleum / Q000009:adverse effects*; D011084:Polycyclic Aromatic Hydrocarbons / Q000009:adverse effects*; D017697:Premenopause; D001335:Vehicle Emissions / Q000032:analysis
D010578:Petroleum; D011084:Polycyclic Aromatic Hydrocarbons; D001335:Vehicle Emissions
breast cancer; case-control; diesel exhaust; vehicle exhaust