Extra-axial primary non-Hodgkin's CNS lymphoma mimicking meningioma, in a 5-year-old immunocompetent child: a rare entity.
We describe a case of a 5-year-old immunocompetent girl who presented with features of raised intracranial pressure with left eye ptosis of 1-month duration. CT scan and MRI of the brain showed an extra-axial, intensely contrast enhancing lesion in the left temporoparieto-occipital region, consistent with meningioma. On open tissue biopsy and immunohistochemistry staining, a diagnosis of B cell non-Hodgkin's lymphoma was made. Six cycles of chemotherapy with cyclophosphamide, adriamycin, vincristine and prednisolone regimen were given and showed a good clinical outcome without any recurrence during follow-up of 5 months.
Department of Neurosurgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Mukesh Kumar
MK
Bhaskar
Department of Neurosurgery, CSM Medical University, Lucknow, Uttar Pradesh, India.
Balkrishna
B
Ojha
Department of Neurosurgery, King George's Medical University, Lucknow, Uttar Pradesh, India.
Manish
M
Jaiswal
Department of Pathology, CSM Medical University, Lucknow, Uttar Pradesh, India.
Mala
M
Sagar
D000941:Antigens; D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001921:Brain / Q000473:pathology*; D001932:Brain Neoplasms / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D016543:Central Nervous System Neoplasms; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007107:Immune System; D007427:Intracranial Pressure; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology; D008228:Lymphoma, Non-Hodgkin; D008579:Meningioma / Q000473:pathology*
D000941:Antigens; D000970:Antineoplastic Agents