Benzoic Acid Interactions Affect Aquatic Properties and Toxicity of Copper Oxide Nanoparticles.
Effects of benzoic acid (BA) on physicochemical properties and ecotoxicities of CuO nanoparticles (CuONPs) in model aqueous media were studied. The CuONPs had larger hydrodynamic sizes and higher surface zeta potentials during 96 h of settling in the presence of BA than when the BA were not present. BA interaction with CuONPs is shown to promote dissolved Cu release from CuONPs in a dose-dependent manner. The contribution of free Cu(2+)-ions to growth inhibition toxicity of the CuONP suspensions at a toxicologically relevant concentration for the green alga Scenedesmus obliquus was around 22 %, indicating that dissolved fraction was not the major source of toxicity of CuONPs. The toxicity of CuONPs increased as the BA concentration increased. BA significantly altered total antioxidant capacity of CuONPs-exposed algal cells. The mechanism of the BA effect on the CuONPs toxicity may be mainly associated with degree of agglomeration, dissolved Cu, and particle-induced oxidative stress.
Collaborative Innovation Center of Atmospheric Environment and Equipment Technology (AEET), Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC), School of Environmental Science and Engineering, Nanjing University of Information Science and Technology, Nanjing, 210044, People's Republic of China. zhuang.wang@nuist.edu.cn.
Zhuang
Z
Wang
Collaborative Innovation Center of Atmospheric Environment and Equipment Technology (AEET), Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC), School of Environmental Science and Engineering, Nanjing University of Information Science and Technology, Nanjing, 210044, People's Republic of China. fh@nuist.edu.cn.
Hao
H
Fang
Collaborative Innovation Center of Atmospheric Environment and Equipment Technology (AEET), Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC), School of Environmental Science and Engineering, Nanjing University of Information Science and Technology, Nanjing, 210044, People's Republic of China.
Se
S
Wang
D000975:Antioxidants / Q000378:metabolism; D019817:Benzoic Acid / Q000737:chemistry*; D003300:Copper / Q000737:chemistry* / Q000633:toxicity; D007477:Ions; D008956:Models, Chemical; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D018384:Oxidative Stress; D010087:Oxides; D013535:Suspensions; D014874:Water Pollutants, Chemical / Q000737:chemistry* / Q000633:toxicity
D000975:Antioxidants; D007477:Ions; D010087:Oxides; D013535:Suspensions; D014874:Water Pollutants, Chemical; D003300:Copper; D019817:Benzoic Acid; C000520:cuprous oxide
Benzoic acid; CuO nanoparticles; Ecotoxicity; Fate; Oxidative stress