Cognition, Depressive Symptoms and Vascular Factors among Southwest Tribal Elders.
OBJECTIVE
Few data exist on cognitive and depressive symptoms and vascular factors in American Indian (AI) elders. Since vascular risk factors increase risk for cognitive impairments, depression and dementia, and since AI elders are at high vascular risk, it is timely to assess the interplay of these factors in comprehensive studies of aging in this population. To begin, pilot studies must be conducted to show these types of data can be collected successfully.


METHODS
A cross-sectional pilot study, the Southwest Heart Mind Study (SHMS).


METHODS
Tribal community in the Southwest United States.


METHODS
AI elders, aged ≥55 years.


METHODS
Cross-cultural demographic, social network and risk factor surveys; tests of cognition, depression and anxiety; physical measurements; blood biochemistries; and APOE genotyping.


RESULTS
SHMS elders were comparable to other rural elder populations on cognitive and depressive symptom scores. The average CogScore was 28.8 (out of 32), the average Geriatric Depression Scale (GDS) was 6.7 (of 30), and the average Hamilton Anxiety Scale was 1.2 (of 4). 32% possessed at least one APOEe4 allele. High vascular risk was evident: 76% were overweight or obese; 54% self-reported history of hypertension; 24% heart trouble; 32% type 2 diabetes; 35% depression; and 24% a family history of serious memory loss. More than 70% reported prescription medication use. 54% cared for someone besides self.


CONCLUSIONS
A better understanding of the burden of vascular risk in relation to cognition and depression among Southwest Tribes is needed.
Department of Family and Community Medicine, University of Arizona.
Francine
F
Gachupin
Department of Family and Community Medicine, University of Arizona.
Michael D
MD
Romero
Department of Family and Community Medicine, University of Arizona.
Willa J
WJ
Ortega
Isleta Pueblo Senior Center, Isleta, New Mexico.
Rita
R
Jojola
Department of Psychiatry, Indiana University.
Hugh
H
Hendrie
Isleta Tribal Governor.
Eddie Paul Sr
EP
Torres
Tribal Council Members.
Frank
F
Lujan
Tribal Council Members.
Michael
M
Lente
Tribal Council Members.
Barbara
B
Sanchez
Tribal Council Members.
Verna
V
Teller
Tribal Council Members.
Fernando
F
Beita
Tribal Council Members.
Ulysses
U
Abeita
Tribal Council Members.
Beatrice
B
Lente
Department of Neurology, SUNY-Downstate Medical Center.
Deborah Ruth
DR
Gustafson
D000368:Aged; D000369:Aged, 80 and over; D002318:Cardiovascular Diseases / Q000208:ethnology; D003071:Cognition; D003430:Cross-Sectional Studies; D003704:Dementia / Q000208:ethnology; D003863:Depression / Q000208:ethnology*; D003924:Diabetes Mellitus, Type 2 / Q000208:ethnology*; D005260:Female; D006801:Humans; D007198:Indians, North American / Q000523:psychology* / Q000706:statistics & numerical data; D008297:Male; D008875:Middle Aged; D010865:Pilot Projects; D012307:Risk Factors; D015206:Southwestern United States; D011795:Surveys and Questionnaires
American Indian; Cognition; Depression; Vascular