Short Term Donor Outcomes After Hepatectomy in Living Donor Liver Transplantation.
OBJECTIVE
To determine the outcome of living-donor liver transplant (LDLT) donors from the first liver transplant program in Pakistan.


METHODS
Cohort study.


METHODS
Shifa International Hospital, Islamabad, from April 2012 to August 2014.


METHODS
A total of 100 live donors who underwent hepatectomy were included. Demographics, etiologies, graft characteristics and operative variables were retrospectively assessed. Outcome was assessed based on morbidity and mortality.


RESULTS
Median donor age was 28 (17 - 45) years and median body mass index (BMI) was 24 kg/m2 (15 - 36). Male to female ratio was 1.5:1. Hepatitis B and C were the most common underlying etiologies and accounted for 79/100 (79%) of LDLT&amp;#039;s. Overall, 93/100 (93%) donors donated a right lobe graft. Median estimated graft weight to recipient body weight (GW/BW) ratio was 1.03 (0.78 - 2). Standard arterial anatomy was present in 56% donors. The 90-day morbidity was 13/100 (13%) and overall morbidity was 17/100 (17%). Bile leak was encountered in 3 (3%) patients. There was no donor mortality.


CONCLUSIONS
Acceptable short-term donor outcomes were achieved in an LDLT program in Pakistan with careful donor selection and planning.
Department of HPB and Liver Transplantation, Shifa International Hospital, Islamabad.
Faisal Saud
FS
Dar
Department of HPB and Liver Transplantation, Shifa International Hospital, Islamabad.
Haseeb
H
Zia
Department of HPB and Liver Transplantation, Shifa International Hospital, Islamabad.
Abu Bakar
AB
Hafeez Bhatti
Department of Radiology, Shifa International Hospital, Islamabad.
Atif
A
Rana
Department of Radiology, Shifa International Hospital, Islamabad.
Rashid
R
Nazer
Department of HPB and Liver Transplantation, Shifa International Hospital, Islamabad.
Rubab
R
Kazmi
Department of Anesthesia, Shifa International Hospital, Islamabad.
Etizaz-Ud-Din
EU
Khan
Department of Anesthesia, Shifa International Hospital, Islamabad.
Nasir Ayub
NA
Khan
Department of Hepatology, Shifa International Hospital, Islamabad.
Muhammad
M
Salih
Department of Hepatology, Shifa International Hospital, Islamabad.
Najmul Hassan
NH
Shah
D000293:Adolescent; D000328:Adult; D001706:Biopsy; D058625:End Stage Liver Disease / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D006498:Hepatectomy; D006509:Hepatitis B / Q000150:complications / Q000601:surgery*; D006526:Hepatitis C / Q000150:complications / Q000601:surgery*; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D009017:Morbidity; D010154:Pakistan / Q000453:epidemiology; D011183:Postoperative Complications; D012189:Retrospective Studies; D009927:Tissue and Organ Procurement / Q000379:methods*; D016896:Treatment Outcome; D055815:Young Adult