A lysin to kill.
An enzyme produced by a bacteriophage can enter human cells and kill intracellular Streptococcus pyogenes.
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, United States.|Department of Microbiology and Immunobiology, Harvard Medical School, Boston, United States.
Anthony O
AO
Gaca
Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, United States.|Department of Microbiology and Immunobiology, Harvard Medical School, Boston, United States.
Michael S
0000-0001-6389-832X
MS
Gilmore
D001435:Bacteriophages; D006801:Humans; D009238:N-Acetylmuramoyl-L-alanine Amidase; D013297:Streptococcus pyogenes
D009238:N-Acetylmuramoyl-L-alanine Amidase
<i>s. pyogenes</i>; bacteriophage; biochemistry; biophysics; endolysin; human; membrane protein; structural biology; structure/function