Autoimmune-mediated peripheral neuropathies and autoimmune pain.
Peripheral neuropathies have diverse acquired and inherited causes. The autoimmune neuropathies represent an important category where treatment is often available. There are overlapping signs and symptoms between autoimmune neuropathies and other forms. Making a diagnosis can be challenging and first assisted by electrophysiologic and sometimes pathologic sampling, with autoimmune biomarkers providing increased assistance. Here we provide a review of the autoimmune and inflammatory neuropathies, their available biomarkers, and approaches to treatment. Also discussed is new evidence to support a mechanism of autoimmune pain.
Department of Neurology, Mayo Clinic, Rochester, MN, USA. Electronic address: klein.christopher@mayo.edu.
Christopher J
CJ
Klein
D001327:Autoimmune Diseases / Q000150:complications*; D006801:Humans; D010146:Pain / Q000150:complications* / Q000276:immunology; D010523:Peripheral Nervous System Diseases / Q000150:complications* / Q000276:immunology
autoimmune; inflammatory; neuropathy; pain