Percutaneous ultrasound-guided core needle biopsy of solid pancreatic masses: Results in 250 patients.
BACKGROUND
To determine the diagnostic accuracy and complications of percutaneous sonographic (US)-guided core needle-needle biopsy in the diagnosis of solid pancreatic masses.


METHODS
Cases of US-guided percutaneous core needle biopsy of solid pancreatic masses performed in our department between July 2009 and June 2015 were analyzed retrospectively. The demographic data, lesions' size and location, pathology results, accuracy, sensitivity, specificity, positive predictive value, negative predictive value, and complications of the biopsies were determined.


RESULTS
A total of 250 patients (150 males, 100 females; age range, 16-88 years; mean age, 64.3 ± 12.1 years) were included in the study. The overall diagnostic accuracy, sensitivity, specificity, positive predictive value, and negative predictive value of all 250 biopsies were 94.8%, 94.3%, 97.2%, 99.5%, and 75%, respectively, and changed to 98.4%, 99%, 94.7%, 99%, and 94.7%, respectively, after the biopsy was repeated in 12 patients. Four (1.6%) major complications, including a pseudoaneurysm of the gastroduodenal artery, and three cases of acute pancreatitis, and one (0.4%) minor complication (a vaso-vagal syncope), were observed. There was no biopsy-related death.


CONCLUSIONS
US-guided percutaneous core needle biopsy is a safe and highly effective method with acceptable complication rates in the diagnosis of solid pancreatic masses. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44:470-473, 2016.
Erciyes University, Medical Faculty, Gevher Nesibe Hospital, Department of Radiology, 38039, Kayseri, Turkey. guvenkahriman@hotmail.com.
Guven
G
Kahriman
Erciyes University, Medical Faculty, Gevher Nesibe Hospital, Department of Radiology, 38039, Kayseri, Turkey.
Nevzat
N
Ozcan
Erciyes University, Medical Faculty, Gevher Nesibe Hospital, Department of Radiology, 38039, Kayseri, Turkey.
Serap
S
Dogan
Erciyes University, Medical Faculty, Gevher Nesibe Hospital, Department of Radiology, 38039, Kayseri, Turkey.
Soner
S
Ozmen
Erciyes University, Medical Faculty, Gevher Nesibe Hospital, Department of Radiology, 38039, Kayseri, Turkey.
Kemal
K
Deniz
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D062005:Biopsy, Large-Core Needle; D005260:Female; D006801:Humans; D061705:Image-Guided Biopsy / Q000379:methods; D008297:Male; D008875:Middle Aged; D010179:Pancreas / Q000000981:diagnostic imaging / Q000473:pathology; D010190:Pancreatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D018084:Ultrasonography, Interventional / Q000379:methods*; D055815:Young Adult
abdomen; neoplasms; pancreas; pancreatic tumor; ultrasound-guided biopsy