Factors affecting quality of life in patients on haemodialysis: a cross-sectional study from Palestine.
Haemodialysis (HD) is a life-sustaining treatment for patients with end-stage renal disease (ESRD). HD can bring about significant impairment in health-related quality of life (HRQOL) and outcomes. Therefore, we sought to describe the patterns of HRQOL and determine the independent factors associated with poor HRQOL in Palestinian patients on HD.



A multicenter cross-sectional study was performed from June 2014 to January 2015 using the EuroQOL-5 Dimensions instrument (EQ-5D-5L) for the assessment of HRQOL. ESRD patients undergoing HD in all dialysis centres in the West Bank of Palestine were approached and recruited for this study. Multiple linear regression was carried out to identify factors that were significantly associated with HRQOL.



Two hundred and sixty-seven patients were participated in the current study giving response rate of 96 %. Overall, 139 (52.1 %) were male, and the mean ± standard deviation age was 53.3 ± 16.2 years. The reported HRQOL as measured by mean EQ-5D-5L index value and Euro QOL visual analogue scale (EQ-VAS) score was 0.37 ± 0.44 and 59.38 ± 45.39, respectively. There was a moderate positive correlation between the EQ-VAS and the EQ-5D-5L index value (r = 0.42, p < 0.001). The results of multiple linear regression showed a significant negative association between HRQOL with age, total number of chronic co-morbid diseases and the total number of chronic medications. However, a significant positive association was found between HRQOL with male gender, university education level and patients who live in village.



Our results provided insight into a number of associations between patient variables and their HRQOL. Healthcare providers should be aware of low HRQOL among patients with no formal education, female gender, patient's residents of refugee camps, multiple co-morbid diseases, multiple chronic medications, and elderly patients to improve their quality of life.
Poison Control and Drug Information Center (PCDIC), College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine. saedzyoud@yahoo.com.|Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine. saedzyoud@yahoo.com.|WHO Collaborating Centre for Drug Information, National Poison Centre, Universiti Sains Malaysia (USM), Penang, 11800, Malaysia. saedzyoud@yahoo.com.
Sa'ed H
SH
Zyoud
PharmD program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Dala N
DN
Daraghmeh
PharmD program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Diana O
DO
Mezyed
PharmD program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Razan L
RL
Khdeir
PharmD program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Mayas N
MN
Sawafta
PharmD program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Nora A
NA
Ayaseh
PharmD program, College of Medicine and Health Sciences, An-Najah National University, Nablus, Palestine.
Ghada H
GH
Tabeeb
Department of Pharmacology and Toxicology, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.
Waleed M
WM
Sweileh
WHO Collaborating Centre for Drug Information, National Poison Centre, Universiti Sains Malaysia (USM), Penang, 11800, Malaysia.
Rahmat
R
Awang
Department of Clinical and Community Pharmacy, College of Medicine and Health Sciences, An-Najah National University, Nablus, 44839, Palestine.
Samah W
SW
Al-Jabi
D000328:Adult; D000368:Aged; D018912:Arabs / Q000523:psychology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007676:Kidney Failure, Chronic / Q000453:epidemiology / Q000523:psychology* / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D008877:Middle East / Q000453:epidemiology; D010865:Pilot Projects; D011788:Quality of Life / Q000523:psychology*; D006435:Renal Dialysis / Q000523:psychology* / Q000639:trends
Haemodialysis; Health-related quality of life; Palestine; Risk factors