[Hemichorea with Contralateral High Signal Intensity Putaminal Lesion on T1-Weighted Images in Non-Ketotic Hyperglycemia].
A 64-year-old diabetic female patient presented with involuntary unilateral hyperkinetic movements of the left limbs. Cranial MRI showed a contralateral high signal intensity putaminal lesion on T1-weighted images without any signal changes in the T2-weighted images. This finding is characteristic for hemichorea-hemiballism associated with insufficiently treated diabetes mellitus. Additionally, proton MR spectroscopy was performed and revealed a decreased N-acetylaspartate/creatine and N-acetylaspartate/choline ratio, indicating neuronal damage of the contralateral putamen.
Klinik und Poliklinik für Neurologie, Uniklinik Köln, Köln.
E I S
EI
Achilles
Institut für Diagnostische und Interventionelle Radiologie, Uniklinik Köln, Köln.
V
V
Maus
Klinik und Poliklinik für Neurologie, Uniklinik Köln, Köln.
G R
GR
Fink
Institut für Diagnostische und Interventionelle Radiologie, Uniklinik Köln, Köln.
D
D
Maintz
Klinik und Poliklinik für Neurologie, Uniklinik Köln, Köln.
T
T
van Eimeren
Institut für Diagnostische und Interventionelle Radiologie, Uniklinik Köln, Köln.
A
A
Mpotsaris
D001224:Aspartic Acid / Q000031:analogs & derivatives / Q000378:metabolism; D002794:Choline / Q000378:metabolism; D002819:Chorea / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003401:Creatine / Q000378:metabolism; D048909:Diabetes Complications / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D003924:Diabetes Mellitus, Type 2 / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D038524:Diffusion Magnetic Resonance Imaging; D004292:Dominance, Cerebral / Q000502:physiology*; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D020158:Hyperglycinemia, Nonketotic / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D009682:Magnetic Resonance Spectroscopy; D008875:Middle Aged; D011699:Putamen / Q000000981:diagnostic imaging* / Q000503:physiopathology*
D001224:Aspartic Acid; D002794:Choline; D003401:Creatine; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human; C000179:N-acetylaspartate