Clinical Evaluation of the Luminex NxTAG Respiratory Pathogen Panel.
An evaluation of the Luminex NxTAG Respiratory Pathogen Panel was performed on 404 clinical respiratory specimens. Clinical sensitivities and specificities of the assay compared to those of the reference methods were 80.0% to 100.0% and 98.9% to 100.0%, respectively. Correct genotyping information was provided for 95.5% of influenza virus A specimens. The closed-tube format of the assay simplified the workflow and minimized carryover contamination.
Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA tangy@mskcc.org.|Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA.
Yi-Wei
http://orcid.org/0000-0003-4888-6771
YW
Tang
New York, New York, USA; Luminex Corporation, Austin, Texas, USA.
Sarah
S
Gonsalves
Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.|Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York, USA.
Janet Y
JY
Sun
Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Jeffrey
J
Stiles
Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Kathleen A
KA
Gilhuley
Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
Albina
A
Mikhlina
New York, New York, USA; Luminex Corporation, Austin, Texas, USA.
Sherry A
SA
Dunbar
Department of Laboratory Medicine, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.
N Esther
http://orcid.org/0000-0003-4399-1249
NE
Babady
New York, New York, USA; Luminex Corporation, Austin, Texas, USA.
Hongwei
H
Zhang
D060005:Genotyping Techniques / Q000379:methods; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000379:methods*; D009975:Orthomyxoviridae; D012141:Respiratory Tract Infections / Q000175:diagnosis* / Q000821:virology; D012680:Sensitivity and Specificity; D014777:Virus Diseases / Q000175:diagnosis* / Q000821:virology; D014780:Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*