Optimising electrogenerated chemiluminescence of quantum dots via co-reactant selection.
We demonstrate that for quantum dot (QD) based electrochemiluminescence (ECL), the commonly used co-reactant does not perform as effectively as potassium persulfate. By exploiting this small change in co-reactant, ECL intensity can be enhanced dramatically in a cathodic-based ECL system. However, TPA remains the preferential co-reactant-based system for anodic ECL. This phenomenon can be rationalised through the relative energy-level profiles of the QD to the co-reactant in conjunction with the applied potential range. This work highlights the importance of understanding the co-reactant pathway for optimising the application of ECL to bioanalytical analysis, in particular for near-infrared (NIR) QDs which can be utilised for analysis in blood. Graphical Abstract Optimising ECL Production Through Careful Selection of Co-Reactions Based on Energetics Involved.
Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK.
Rebekah
R
Russell
Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK.
Alasdair J
AJ
Stewart
Department of Pure and Applied Chemistry, Technology and Innovation Centre, University of Strathclyde, 99 George Street, Glasgow, G1 1RD, UK. lynn.dennany@strath.ac.uk.
Lynn
L
Dennany
D019187:Cadmium Compounds / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry; D055664:Electrochemical Techniques / Q000379:methods*; D004566:Electrodes; D049449:Luminescence; D049408:Luminescent Agents / Q000737:chemistry*; D008163:Luminescent Measurements / Q000379:methods*; D010084:Oxidation-Reduction; D017680:Potassium Compounds / Q000737:chemistry; D045663:Quantum Dots / Q000737:chemistry*; D012643:Selenium / Q000737:chemistry*; D013431:Sulfates / Q000737:chemistry; D013440:Sulfides / Q000737:chemistry*; D013691:Tellurium / Q000737:chemistry*; D017967:Zinc Compounds / Q000737:chemistry*
D019187:Cadmium Compounds; D049408:Luminescent Agents; D017680:Potassium Compounds; D013431:Sulfates; D013440:Sulfides; D017967:Zinc Compounds; C009007:potassium persulfate; D048271:Chitosan; D012643:Selenium; C031238:zinc sulfide; D013691:Tellurium; C028337:cadmium telluride
Electroanalytical methods; Electrochemiluminescence; Quantum dots