Coping strategies modify risk of depression associated with hematopoietic cell transplant symptomatology.
To determine whether coping strategies modify the risk of depression among allogeneic recipients experiencing post-transplant-related symptomatology, 105 participants (mean age = 52 years, 42% female) completed questionnaires 90 days post-transplant. A total of 28 percent reported depressive symptoms. Univariate correlations indicated that depression was associated with greater transplant-related symptomatology and avoidance, acceptance/resignation, and emotional discharge coping. Depression was negatively associated with problem-solving coping. Moderator analyses indicated that transplant-related symptomatology was significantly associated with depression among patients who frequently used maladaptive coping and rarely used adaptive coping. These data suggest that transplant-related symptomatology, combined with maladaptive coping, place patients at risk of depression.
1 Moffitt Cancer Center, USA.|2 Universitat Autònoma de Barcelona, Spain.
Anna
A
Barata
1 Moffitt Cancer Center, USA.
Brian D
BD
Gonzalez
1 Moffitt Cancer Center, USA.
Steven K
SK
Sutton
3 University of South Florida, USA.
Brent J
BJ
Small
1 Moffitt Cancer Center, USA.
Paul B
PB
Jacobsen
1 Moffitt Cancer Center, USA.
Teresa
T
Field
1 Moffitt Cancer Center, USA.
Hugo
H
Fernandez
1 Moffitt Cancer Center, USA.
Heather Sl
HS
Jim
D000223:Adaptation, Psychological; D000328:Adult; D003863:Depression / Q000523:psychology*; D003866:Depressive Disorder / Q000523:psychology*; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000523:psychology* / Q000628:therapy*
cancer; coping; depression; hematopoietic stem cell transplantation; oncology