Prospective memory impairment in chemotherapy-exposed early breast cancer survivors: Preliminary evidence from a clinical test.
We report the results of a secondary analysis of a cross-sectional study (Paquet et al., 2013 ) to evaluate the cognitive operations involved in prospective memory (PM) deficits exhibited by chemotherapy-exposed breast cancer (BC) survivors. PM was assessed with the memory for intentions screening test administered to 80 patients and 80 healthy controls. Patients performed worse than controls on the PM tasks and had more "omission" errors (indices of the prospective component of the tasks) than the controls. No group differences emerged on a recognition test. Although further studies will be needed to disentangle the multiple cognitive operations involved in PM, these findings are consistent with the notion that self-initiated retrieval processes rather than encoding are implicated in PM impairment among BC survivors.
a Department of Psychology , Carleton University , Ottawa , Ontario , Canada.
Marc
M
Bedard
b The Ottawa Hospital Cancer Centre , Ottawa , Ontario , Canada.
Shailendra
S
Verma
c Department of Neuropsychology , The Ottawa Hospital , Ottawa , Ontario , Canada.
Barbara
B
Collins
b The Ottawa Hospital Cancer Centre , Ottawa , Ontario , Canada.
Xinni
X
Song
a Department of Psychology , Carleton University , Ottawa , Ontario , Canada.
Lise
L
Paquet
D000970:Antineoplastic Agents / Q000009:adverse effects*; D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000523:psychology*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008569:Memory Disorders / Q000139:chemically induced*; D061212:Memory, Episodic; D008875:Middle Aged; D009367:Neoplasm Staging; D009483:Neuropsychological Tests; D017741:Survivors / Q000523:psychology* / Q000706:statistics & numerical data
D000970:Antineoplastic Agents
breast cancer; chemobrain; chemotherapy; cognitive deficits; prospective memory impairment