Future Research Directions for Multimorbidity Involving Cardiovascular Diseases.
Multimorbidity, defined as the co-occurrence of two or more chronic conditions, increases with age and may be found in approximately two-thirds of older adults in population studies, commonly including a variety of cardiovascular risk factors and chronic diseases. This article offers a research agenda for cardiovascular disease from a patient-centered multimorbidity perspective. Definitional issues remain for multimorbidity, along with high interest in understanding the inter-relationships between aging, diseases, treatments, and organ dysfunction in the development and progression of multimorbidity. Clinical trials, practice-based and population-based observational studies, and linkages of big data can play a role in improving health outcomes among persons with multimorbidity.
Division of Geriatrics and Clinical Gerontology, National Institute on Aging, National Institutes of Health, 7201 Wisconsin Avenue, Suite 3c307, MSC 9205, Bethesda, MD 20892-9205, USA. Electronic address: msalive@msn.com.
Marcel E
ME
Salive
D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000628:therapy; D015897:Comorbidity; D006801:Humans; D010346:Patient Care Management / Q000379:methods / Q000458:organization & administration / Q000639:trends; D012106:Research / Q000639:trends*
Aging; Chronic disease; Multimorbidity; Multiple morbidities