Current evidence for the effectiveness of heated and humidified high flow nasal cannula supportive therapy in adult patients with respiratory failure.
High flow nasal cannula (HFNC) supportive therapy has emerged as a safe, useful therapy in patients with respiratory failure, improving oxygenation and comfort. Recently several clinical trials have analyzed the effectiveness of HFNC therapy in different clinical situations and have reported promising results. Here we review the current knowledge about HFNC therapy, from its mechanisms of action to its effects on outcomes in different clinical situations.
Critical Care Department, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Barcelona, Spain. oroca@vhebron.net.|Ciber Enfermedades Respiratorias (Ciberes), Instituto de Salud Carlos III, Madrid, Spain. oroca@vhebron.net.
Oriol
O
Roca
Critical Care Department, Virgen de la Salud Hospital, Toledo, Spain.
Gonzalo
G
Hernández
Respiratory Medicine Department, Ramón y Cajal University Hospital, Madrid, Spain.
Salvador
S
Díaz-Lobato
Emergency Medicine Department, Alicante General Hospital, Alicante, Spain.
José M
JM
Carratalá
Anesthesiology Department, De Cruces General Hospital, Bilbao, Spain.
Rosa M
RM
Gutiérrez
Ciber Enfermedades Respiratorias (Ciberes), Instituto de Salud Carlos III, Madrid, Spain.|Critical Care Department, Del Mar University Hospital, IMIM (Medical Research del Mar Hospital Institute), Barcelona, Spain.
Joan R
JR
Masclans
D000328:Adult; D000072601:Cannula; D006801:Humans; D000068998:Humidifiers; D010102:Oxygen Inhalation Therapy / Q000379:methods*; D012131:Respiratory Insufficiency / Q000628:therapy*
High flow nasal cannula; High flow oxygen therapy; Respiratory failure