Inflammatory myopathies and overlap syndromes: Update on histological and serological profile.
The term 'inflammatory myopathies' (IMs) comprise a group of muscle diseases formed by four main categories known as polymyositis (PM), dermatomyositis (DM), inclusion body myositis (IBM) and immune-mediated necrotizing myopathy (IMNM). Due to the increasing evidence of IMs over the course of different autoimmune diseases, the overlap myositis (OM) has been recently recognized as a possible stand-alone entity. IMs are characterized by a wide spectrum of autoantibodies, and the panel of myositis-associated autoantibodies (MAA) has dramatically increased over the last years giving the clinicians a further crucial support to differentiate the different types of myositis. This study aims to collect the most relevant evidence published up to date on the most commonly described OM with a particular emphasis on their histological aspects and also serological features.
Dipartimento di Medicina Interna e Specialita' Mediche, UOC Reumatologia, SapienzaUniversita' di Roma, Italy. Electronic address: serena.colafrancesco18@gmail.com.
Serena
S
Colafrancesco
Dipartimento di Medicina Interna e Specialita' Mediche, UOC Reumatologia, SapienzaUniversita' di Roma, Italy.
Roberta
R
Priori
Dipartimento di Medicina Interna e Specialita' Mediche, UOC Reumatologia, SapienzaUniversita' di Roma, Italy. Electronic address: guido.valesini@uniroma1.it.
Guido
G
Valesini
D001323:Autoantibodies / Q000276:immunology; D001327:Autoimmune Diseases / Q000276:immunology*; D006801:Humans; D009220:Myositis / Q000276:immunology*; D000074079:Undifferentiated Connective Tissue Diseases / Q000276:immunology*
D001323:Autoantibodies
Autoantibodies; Biopsy; Histology; Myositis; Overlap