One new berberine from the branches and leaves of Polyalthia obliqua Hook.f. & Thomson.
One new alkaloid consanguine B (1), together with 10 known alkaloids (2-11), were isolated from ethanol extract of the branches and leaves of Polyalthia obliqua Hook.f. & Thomson collected in the Hainan Province, China. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their cytotoxic activities. Compound 1 showed weak cytotoxic activities against Hela and MCF-7 human cancer cell lines.
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Li-Jun
LJ
Wu
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Cai-Juan
CJ
Zheng
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Liu-Kai
LK
Wang
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Chang-Ri
CR
Han
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Xiao-Ping
XP
Song
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Guang-Ying
GY
Chen
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Xue-Ming
XM
Zhou
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Shou-Yuan
SY
Wu
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Xiao-Bao
XB
Li
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Meng
M
Bai
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Chun-Xin
CX
Liu
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education, College of Chemistry and Chemical Engineering , Hainan Normal University , Haikou , China.
Jun
J
Yao
D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000494:pharmacology*; D001599:Berberine / Q000737:chemistry; D001600:Berberine Alkaloids / Q000302:isolation & purification / Q000494:pharmacology; D002681:China; D004354:Drug Screening Assays, Antitumor; D006367:HeLa Cells / Q000187:drug effects; D006801:Humans; D061986:MCF-7 Cells / Q000187:drug effects; D015394:Molecular Structure; D010936:Plant Extracts / Q000737:chemistry; D018515:Plant Leaves / Q000737:chemistry; D031044:Polyalthia / Q000737:chemistry*
D000470:Alkaloids; D000972:Antineoplastic Agents, Phytogenic; D001600:Berberine Alkaloids; D010936:Plant Extracts; C000619084:consanguine B; D001599:Berberine
Polyalthia oblique; alkaloid; cytotoxic activities