Relationship between blood pressure reverse dipping and type 2 diabetes in hypertensive patients.
Recent studies suggested that nocturnal variations of blood pressure (BP) were closely related to type 2 diabetes. However, little information has been revealed about the relationship between reverse-dipper pattern of BP and type 2 diabetes. In this cross-sectional study, BP variations of 531 hypertensive patients were evaluated with ambulatory BP monitoring (ABPM). Diagnosis of diabetes in Chinese adults was made according to diabetes diagnostic criteria of 2015. Multivariate logistic regression was used to examine the relationships between type 2 diabetes and ABPM results. In the study, patients with reverse-dipper pattern (32.3%) had the highest prevalence of type 2 diabetes compared with dippers (21.4%) and nondippers (23.3%). After multivariate logistic regression, reverse-dipper BP pattern (OR 2.067, P = 0.024) and nondipper BP pattern (OR 1.637, P = 0.039) were found to be correlated with type 2 diabetes compared with dipper pattern. The results of our study also suggested that type 2 diabetes might contribute to the reverse-dipper pattern of BP (OR 1.691, P = 0.023). In addition, fasting glucose was negatively correlated with the decline rate of nocturnal SBP (r = -0.095, P = 0.029). Reverse-dipper pattern of BP in ABPM may be independently associated with type 2 diabetes in patients with hypertension.
Department of Ultrasound, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Lu
L
Sun
Department of Emergency Medicine, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Bin
B
Yan
Department of Emergency Medicine, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Ya
Y
Gao
Department of Cardiology, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Dan
D
Su
Department of Emergency Medicine, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Liyuan
L
Peng
Department of Endocrinology, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Yang
Y
Jiao
Department of Endocrinology, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Yuhuan
Y
Wang
Department of Ultrasound, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Donggang
D
Han
Department of Emergency Medicine, the Second Affiliated Hospital, Xi'an Jiaotong University, Xi'an, China.
Gang
G
Wang
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001794:Blood Pressure / Q000502:physiology; D018660:Blood Pressure Monitoring, Ambulatory; D002681:China / Q000453:epidemiology; D002940:Circadian Rhythm; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged