[Characteristics of cognitive impairment of different infarct locations among patients after acute ischemic stroke].
OBJECTIVE
To investigate the characteristics of cognitive function changes of different infarct sites among patients after acute ischemic stroke, so as to provide theoretical basis for preventing and treating vascular cognitive dysfunction.


METHODS
One hundred and five cases of acute ischemic stroke within fourteen days meeting the standard set were enrolled, and they were tested by Mini-Mental State Examination (MMSE) and Montreal Cognitive Assessment (MoCA). And the characteristics of cognitive changes with different infarction sites were analyzed.


RESULTS
Patients with acute stroke suffered cognitive impairment.The significantly impaired cognitive domains in MMSE were: graphics execution in patients with left hemisphere infarction (P=0.027); verbal repetition in frontal infarction (P=0.003); short memory (P=0.04) and verbal repetition (P=0.007) in parietal infarction.The significantly impaired cognitive domains in MoCA were: language (P=0.002), naming (P=0.011), attention (P=0.028) and time orientation (P=0.031) in frontal infarction; delayed memory (P<0.001), attention (P=0.041), language (P=0.049) and visual space and executive ability (P=0.049) in parietal infarction; attention in temporal infarction (P=0.045); language (P=0.009) and time orientation (P=0.026) in basal ganglia region infarction.


CONCLUSIONS
Most ischemic stroke patients at acute phase suffered cognitive impairment and the characteristics of cognitive changes differed according to different infarction sites.Comprehensive assessment of cognitive impairment after acute stroke is of great importance.
Department of Neurology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
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D001288:Attention; D001921:Brain / Q000473:pathology; D020520:Brain Infarction / Q000473:pathology*; D003071:Cognition; D003072:Cognition Disorders; D060825:Cognitive Dysfunction / Q000145:classification / Q000503:physiopathology*; D006801:Humans; D007802:Language; D008568:Memory; D009483:Neuropsychological Tests; D020521:Stroke / Q000503:physiopathology*