The Emerging Roles of Coronary Computed Tomographic Angiography: Acute Chest Pain Evaluation and Screening for Asymptomatic Individuals.
Coronary computed tomographic angiography (CCTA) has been widely available since 2004. After that, the diagnostic accuracy of CCTA has been extensively validated with invasive coronary angiography for detection of coronary arterial stenosis. In this paper, we reviewed the updated evidence of the role of CCTA in both scenarios including acute chest pain and screening in asymptomatic adults. Several large-scale studies have been conducted to evaluate the diagnostic value of CCTA in the context of acute chest pain patients. CCTA could play a role in delivering more efficient care. For risk stratification of asymptomatic patients using CCTA, latest studies have revealed incremental benefits. Future studies evaluating the totality of plaque characteristics may be useful for determining the role of noncalcified plaque for risk stratification in asymptomatic individuals.


BACKGROUND
Acute chest pain • Computed tomography • Coronary artery disease • Health screening • Stable angina.
Department of Medical Imaging;
Ning
N
Chien
Cardiovascular Center and Division of Cardiology, Department of Internal Medicine;
Tzung-Dau
TD
Wang
Department of Medical Imaging;
Yeun-Chung
YC
Chang
Cardiovascular Center and Division of Cardiology, Department of Internal Medicine;
Po-Chih
PC
Lin
Department of Medical Imaging;
Yao-Hui
YH
Tseng
Department of Medical Imaging;
Yee-Fan
YF
Lee
Department of Medical Imaging;
Wei-Chun
WC
Ko
Department of Internal Medicine, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei;
Bai-Chin
BC
Lee
Department of Medical Imaging; ; Department of Medical Imaging, National Taiwan University Hospital Hsin-Chu Branch, Hsinchu, Taiwan.
Wen-Jeng
WJ
Lee