Effects of a buried magnetic field on cranial bone reconstruction in rats.
The understanding of bone repair phenomena is a fundamental part of dentistry and maxillofacial surgery. Objective The present study aimed to evaluate the influence of buried magnetic field stimulation on bone repair in rat calvaria after reconstruction with autogenous bone grafts, synthetic powdered hydroxyapatite, or allogeneic cartilage grafts, with or without exposure to magnetic stimulation. Material and Methods Ninety male Wistar rats were divided into 18 groups of five animals each. Critical bone defects were created in the rats' calvaria and immediately reconstructed with autogenous bone, powdered synthetic hydroxyapatite or allogeneic cartilage. Magnetic implants were also placed in half the animals. Rats were euthanized for analysis at 15, 30, and 60 postoperative days. Histomorphometric analyses of the quantity of bone repair were performed at all times. Results These analyses showed significant group by postoperative time interactions (p=0.008). Among the rats subjected to autogenous bone reconstruction, those exposed to magnetic stimulation had higher bone fill percentages than those without magnetic implants. Results also showed that the quality of bone repair remained higher in the former group as compared to the latter at 60 postoperative days. Conclusions After 60 postoperative days, bone repair was greater in the group treated with autogenous bone grafts and exposed to a magnetic field, and bone repair was most pronounced in animals treated with autogenous bone grafts, followed by those treated with powdered synthetic hydroxyapatite and allogeneic cartilage grafts.
Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Maíra Cavallet de
MC
Abreu
Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Deise
D
Ponzoni
Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Renan
R
Langie
Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Felipe Ernesto
FE
Artuzi
Departamento de Cirurgia Oral e Maxilofacial, Faculdade de Odontologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brasil.
Edela
E
Puricelli
D000818:Animals; D001861:Bone Regeneration / Q000502:physiology*; D018786:Bone Substitutes / Q000627:therapeutic use; D016025:Bone Transplantation / Q000379:methods*; D017886:Durapatite / Q000627:therapeutic use; D055909:Magnetic Field Therapy / Q000379:methods*; D060526:Magnetic Fields; D008297:Male; D011897:Random Allocation; D017208:Rats, Wistar; D015203:Reproducibility of Results; D012886:Skull / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome
D018786:Bone Substitutes; D017886:Durapatite