Convenient synthesis of phosphonohydrazines from arylamines.
Phosphonohydrazines were prepared in good yield from corresponding arylamines by a one-pot reaction through diazotization with an organic nitrite and treatment with a trialkyl phosphite. The trialkyl phosphite is postulated to function as a nucleophile as well as a reducing agent.
Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132 USA.
Greggory T
GT
Kent
Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132 USA.
Daniel J
DJ
Blackburn
Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132 USA.
Joseph R
JR
Gonzalez
Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132 USA.
Megan L
ML
Mayer
Department of Chemistry and Biochemistry, San Francisco State University, San Francisco, CA 94132 USA.
Weiming
W
Wu
alkyl nitrite; arylamine; diazo compounds; phosphonohydrazine; reduction; trialkyl phosphite