Connecting the regulatory genome.
Determining how the evolving genome-wide map of distal regulatory elements is connected with target genes has remained a significant challenge, despite progress in understanding chromatin architecture and regulation. A new study presents a computational approach for predicting distal element-gene interactions.
Departments of Genome Sciences and Medicine at the University of Washington and at the Altius Institute for Biomedical Sciences, Seattle, Washington, USA.
John
J
Stamatoyannopoulos
D002843:Chromatin; D047369:Chromatin Immunoprecipitation; D002874:Chromosome Mapping; D016678:Genome; D012045:Regulatory Sequences, Nucleic Acid
D002843:Chromatin