Use of Postexposure Prophylaxis After Occupational Exposure to Zaire ebolavirus.
From September 2014 to April 2015, 6 persons who had occupational exposures to Zaire ebolavirus in West Africa received investigational agent rVSV-ZEBOV or TKM-100802 for postexposure prophylaxis and were monitored in the United States. All patients experienced self-limited symptoms after postexposure prophylaxis; none developed Ebola virus disease.
Centers for Disease Control and Prevention.
Karen K
KK
Wong
National Institute of Allergy and Infectious Diseases.
Richard T
RT
Davey
University of Nebraska Medical Center, Omaha.
Angela L
AL
Hewlett
Emory University, Atlanta, Georgia.
Colleen S
CS
Kraft
Emory University, Atlanta, Georgia.
Aneesh K
AK
Mehta
Emory University, Atlanta, Georgia.
Mark J
MJ
Mulligan
Emory University, Atlanta, Georgia.
Allison
A
Beck
US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland.
William
W
Dorman
University of Nebraska Medical Center, Omaha.
Christopher J
CJ
Kratochvil
Emory University, Atlanta, Georgia.
Lilin
L
Lai
National Institute of Allergy and Infectious Diseases.
Tara N
TN
Palmore
Emory University, Atlanta, Georgia.
Susan
S
Rogers
University of Nebraska Medical Center, Omaha.
Philip W
PW
Smith
Critical Care Medicine Department, Clinical Center, National Institutes of Health, Bethesda.
Anthony F
AF
Suffredini
US Army Medical Research Institute of Infectious Diseases, Frederick, Maryland.
Mark
M
Wolcott
Centers for Disease Control and Prevention.
Ute
U
Ströher
Centers for Disease Control and Prevention.
Timothy M
TM
Uyeki
D000328:Adult; D000354:Africa, Western; D029043:Ebolavirus / Q000502:physiology*; D005260:Female; D019142:Hemorrhagic Fever, Ebola / Q000175:diagnosis / Q000517:prevention & control* / Q000821:virology; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure; D056990:Post-Exposure Prophylaxis; D012189:Retrospective Studies; D014481:United States
Ebola virus; TKM-Ebola; postexposure prophylaxis; vesicular stomatitis virus