[Exclusive radiotherapy for a facial basal cell carcinoma with trigeminal ganglion involvement].
Basal cell carcinomas with symptomatic perineural invasion are rare entities. We report the case of a 60year-old man (with a grafted kidney), surgically treated in 2007 for a sclerodermiform basal cell carcinoma infiltrating the left nostril. Five years later, a painful left hemifacial hypoesthesia associated with an ulcus rodens of the nasolabial fold appeared. A biopsy confirmed a recurrence. MRI showed an enhancement of the trigeminal ganglion. The patient had a trigeminal perineural invasion secondary to a cutaneous basal cell carcinoma. He received a local intensity-modulated radiotherapy alone (70Gy in 33 sessions), administered from the skin tumour to the skull base. Three years after the end of treatment, the patient is in radiological and clinical remission, with partial recovery of the hypoesthesia. Evolution was marked by iterative corneal ulcers and decreased visual acuity. Modalities of treatment by surgery and/or radiation therapy and complications are poorly described in the literature.
Service de chirurgie maxillofaciale, stomatologie et chirurgie plastique de la face, hôpital Estaing CHU de Clermont-Ferrand, université d'Auvergne, 1, place Lucie-Aubrac, 63000 Clermont-Ferrand, France. Electronic address: marielle.longeac@gmail.fr.
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Longeac
Département de radiothérapie, centre Jean-Perrin, 58, rue Montalembert, BP 392C, 63011 Clermont-Ferrand cedex 1, France.
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Lapeyre
Service de chirurgie maxillofaciale, stomatologie et chirurgie plastique de la face, hôpital Estaing CHU de Clermont-Ferrand, université d'Auvergne, 1, place Lucie-Aubrac, 63000 Clermont-Ferrand, France.
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Delbet Dupas
Service de chirurgie maxillofaciale, stomatologie et chirurgie plastique de la face, hôpital Estaing CHU de Clermont-Ferrand, université d'Auvergne, 1, place Lucie-Aubrac, 63000 Clermont-Ferrand, France; UMR Inserm/UdA, U1107, Neuro-Dol, Trigeminal Pain and Migraine, BP 10448, 63000 Clermont-Ferrand, France.
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Barthélémy
Service de chirurgie maxillofaciale, stomatologie et chirurgie plastique de la face, hôpital Estaing CHU de Clermont-Ferrand, université d'Auvergne, 1, place Lucie-Aubrac, 63000 Clermont-Ferrand, France; UMR Inserm/UdA, U1107, Neuro-Dol, Trigeminal Pain and Migraine, BP 10448, 63000 Clermont-Ferrand, France.
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Pham Dang
D002280:Basal Cell Carcinoma / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D006987:Hypesthesia / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D050397:Radiotherapy, Intensity-Modulated; D012878:Skin Neoplasms / Q000473:pathology / Q000532:radiotherapy*; D012668:Trigeminal Ganglion / Q000473:pathology* / Q000528:radiation effects*
Basal cell carcinoma; Carcinome basocellulaire; Ganglion de Gasser; Invasion; Radiotherapy; Radiothérapie; Trigeminal ganglion