Continuous Renal Replacement Therapy for the Management of Acid-Base and Electrolyte Imbalances in Acute Kidney Injury.
Continuous renal replacement therapy (CRRT) is used to manage electrolyte and acid-base imbalances in critically ill patients with acute kidney injury. Although a standard solution and prescription is acceptable in most clinical circumstances, specific disorders may require a tailored approach such as adjusting fluid composition, regulating CRRT dose, and using separate intravenous infusions to mitigate and correct these disturbances. Errors in fluid prescription, compounding, or delivery can be rapidly fatal. This article provides an overview of the principles of acid-base and electrolyte management using CRRT.
Division of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; and Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI. Electronic address: Lyessay1@hfhs.org.
Lenar
L
Yessayan
Division of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; and Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI.
Jerry
J
Yee
Division of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; and Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI.
Stan
S
Frinak
Division of Nephrology and Hypertension, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI; and Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI.
Balazs
B
Szamosfalvi
D000137:Acid-Base Imbalance / Q000150:complications / Q000628:therapy*; D000138:Acidosis / Q000150:complications / Q000628:therapy; D058186:Acute Kidney Injury / Q000150:complications / Q000628:therapy*; D000471:Alkalosis / Q000150:complications / Q000628:therapy; D003422:Critical Care; D016638:Critical Illness; D006801:Humans; D006947:Hyperkalemia / Q000150:complications / Q000628:therapy; D007010:Hyponatremia / Q000150:complications / Q000628:therapy; D017582:Renal Replacement Therapy / Q000379:methods*; D014883:Water-Electrolyte Imbalance / Q000150:complications / Q000628:therapy*
Acidosis; Alkalosis; CRRT; Hyperkalemia; Hyponatremia