BRAF-Like Colorectal Cancer Cells Are Selectively Dependent on RANBP2.
In BRAF-like colorectal cancer cells, RANBP2 loss induces mitotic abnormalities and cell death.
D015179:Colorectal Neoplasms / Q000235:genetics* / Q000378:metabolism* / Q000473:pathology; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D018832:Molecular Chaperones / Q000378:metabolism*; D009154:Mutation; D028861:Nuclear Pore Complex Proteins / Q000378:metabolism*; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics* / Q000378:metabolism
D018832:Molecular Chaperones; D028861:Nuclear Pore Complex Proteins; C094493:ran-binding protein 2; D048493:Proto-Oncogene Proteins B-raf