Correlation of Allograft Weight to Recipient Body Weight Index on Renal Function in Kidney Transplantation.
BACKGROUND
The function of renal transplant grafts can be modified by many factors. In one study of graft weight/weight of the recipient, it was concluded to avoid renal transplantation in patients with kidneys with a low ratio between the graft and recipient weight (<2.5 g/kg).


OBJECTIVE
The objective of this study was to describe the association between renal allograft weight and renal function 1 month after renal transplantation in the Mexican population.


METHODS
We studied patients who underwent transplantation from living or cadaveric donors with 1 month of follow-up with a functioning graft. An observational, retrospective, analytic study from January 1, 2014 to November 1, 2014 was conducted. Graft weight, donor weight, recipient weight, age, donor gender, recipient creatinine, and renal function were recorded.


RESULTS
A total of 88 patients were included: 35 women (39.8%) and 53 men (60.2%). Sixty (68%) received kidneys from living donors and 28 (31.8%) from deceased donors. Mean recipient body mass index (BMI) was 24.7 (±2.6). Mean graft weight was 152 g (±33.9). Creatinine at 1 month post-transplantation was 1.6 mg/dL (±2.0). Using a linear regression model cold ischemia time was related to serum creatinine at 1 month post-transplantation (P = .020). Using multivariate analysis, significance was observed with respect to these indexes and recipient renal function. Recipient gender also was related and showed statistical significance (P = .015).


CONCLUSIONS
Renal graft function depends on many factors including the amount of functional renal mass and nephrons required according to the recipient's weight. The donor kidney weigt (DKW) / receptor body weigt (RBW) index should be considered as selection criteria of donors.
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico; Department of Organ Donation and Transplantation, Hospital General de Mexico "Dr. Eduardo Liceaga," Mexico City, Mexico. Electronic address: asfa@live.com.mx.
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García-Covarrubias
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Pliego
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Bermudez
Department of Organ Donation and Transplantation, Hospital General de Mexico "Dr. Eduardo Liceaga," Mexico City, Mexico.
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Cicero
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Cancino
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Bautista
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Guerrero
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Silva
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Hernández
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Rodriguez
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Cruz
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Ibarra
Department of Kidney Transplantation, Centro Médico Nacional SXXI, Instituto Mexicano Del Seguro Social, Mexico City, Mexico.
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Espinoza
D000328:Adult; D064591:Allografts; D015992:Body Mass Index; D001835:Body Weight; D005260:Female; D005919:Glomerular Filtration Rate / Q000502:physiology*; D006801:Humans; D007668:Kidney / Q000503:physiopathology*; D016030:Kidney Transplantation; D019520:Living Donors; D008297:Male; D009929:Organ Size; D012189:Retrospective Studies