Mevastatin suppresses melanogenesis by lowering the levels of cyclic adenosine monophosphate and cholesterol.
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.
Heun Joo
HJ
Lee
Asan Institute for Life Science, Seoul, Korea.
Soo Youn
SY
Jo
Department of Genetic Engineering, College of Life Sciences, Kyung Hee University, Yongin, Korea. jshwang@khu.ac.kr.
Jae Sung
JS
Hwang
Department of Dermatology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea. csesnumd@gmail.com.
Sung Eun
SE
Chang
D000818:Animals; D000924:Anticholesteremic Agents / Q000494:pharmacology*; D045744:Cell Line, Tumor; D002784:Cholesterol / Q000378:metabolism*; D000242:Cyclic AMP / Q000378:metabolism*; D008148:Lovastatin / Q000031:analogs & derivatives* / Q000494:pharmacology; D008543:Melanins / Q000096:biosynthesis*; D051379:Mice
D000924:Anticholesteremic Agents; D008543:Melanins; C012258:mevastatin; D002784:Cholesterol; D008148:Lovastatin; D000242:Cyclic AMP
cholesterol; cyclic AMP; melanogenesis; mevastatin; microphthalmia-associated transcription factor