Magnitude and Impact of Multimorbidity on Clinical Outcomes in Older Adults with Cardiovascular Disease: A Literature Review.
The authors aim to synthesize the current literature on the magnitude and impact of multimorbidity on clinical outcomes in older adults with cardiovascular disease (CVD). Most studies reported a significant association between the number of morbidities and the risk of dying. Multimorbidity was assessed either by counting the number of conditions or by use of the Charlson or Elixhauser indices. There are limited data available on the magnitude and impact of multimorbidity on clinical outcomes in patients with CVD and essentially no data on universal health outcomes (eg, health-related quality of life, symptom burden, and function).
Division of Geriatric Medicine, Department of Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, 425 North Lake Avenue, Worcester, MA 01605, USA; Department of Quantitative Health Sciences, University of Massachusetts Medical School, 425 North Lake Avenue, Worcester, MA 01605, USA.
Mayra
M
Tisminetzky
Department of Quantitative Health Sciences, University of Massachusetts Medical School, 425 North Lake Avenue, Worcester, MA 01605, USA; Division of Cardiovascular Medicine, Department of Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, 425 North Lake Avenue, Worcester, MA 01605, USA.
Robert
R
Goldberg
Division of Geriatric Medicine, Department of Medicine, Meyers Primary Care Institute, University of Massachusetts Medical School, 425 North Lake Avenue, Worcester, MA 01605, USA; Department of Quantitative Health Sciences, University of Massachusetts Medical School, 425 North Lake Avenue, Worcester, MA 01605, USA. Electronic address: jerry.gurwitz@umassmed.edu.
Jerry H
JH
Gurwitz
D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology / Q000628:therapy; D015897:Comorbidity; D006801:Humans; D010346:Patient Care Management / Q000379:methods; D063868:Patient Outcome Assessment
Cardiovascular disease; Clinical outcomes; Elderly; Multimorbidity