Presumed Second Focus of Lung Immunoglobulin G4-Related Disease Found to be Adenocarcinoma.
We describe a patient presenting with bilateral radiologically similar lung lesions initially diagnosed as immunoglobulin (Ig) G4-related disease from biopsy of one lesion, but radiographic changes 6 months later prompted biopsy of the second lesion and showed adenocarcinoma. No case of lung IgG4-related disease and a distant lung malignancy has been previously reported. This is notable because lung IgG4-related disease often manifests in multiple thoracic locations but is diagnosed from a representative biopsy specimen.
MD/PhD Program, Oregon Health and Science University, Portland, Oregon.
Gregory D
GD
Scott
Department of Pathology, Oregon Health and Science University, Portland, Oregon.
David A
DA
Sauer
Department of Pathology/Laboratory, Portland VA Medical Center, Portland, Oregon.
Kirsten M
KM
Woolf
Division of Cardiothoracic Surgery, Oregon Health and Science University, Portland, Oregon.
Mithran S
MS
Sukumar
Division of Cardiothoracic Surgery, Oregon Health and Science University, Portland, Oregon. Electronic address: tieub@ohsu.edu.
Brandon H
BH
Tieu
D000230:Adenocarcinoma / Q000175:diagnosis*; D000077192:Adenocarcinoma of Lung; D006801:Humans; D007074:Immunoglobulin G / Q000276:immunology*; D008171:Lung Diseases / Q000175:diagnosis*; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed
D007074:Immunoglobulin G