Hyoid bone fusion and bone density across the lifespan: prediction of age and sex.
The hyoid bone supports the important functions of swallowing and speech. At birth, the hyoid bone consists of a central body and pairs of right and left lesser and greater cornua. Fusion of the greater cornua with the body normally occurs in adulthood, but may not occur at all in some individuals. The aim of this study was to quantify hyoid bone fusion across the lifespan, as well as assess developmental changes in hyoid bone density. Using a computed tomography imaging studies database, 136 hyoid bones (66 male, 70 female, ages 1-to-94) were examined. Fusion was ranked on each side and hyoid bones were classified into one of four fusion categories based on their bilateral ranks: bilateral distant non-fusion, bilateral non-fusion, partial or unilateral fusion, and bilateral fusion. Three-dimensional hyoid bone models were created and used to calculate bone density in Hounsfield units. Results showed a wide range of variability in the timing and degree of hyoid bone fusion, with a trend for bilateral non-fusion to decrease after age 20. Hyoid bone density was significantly lower in adult female scans than adult male scans and decreased with age in adulthood. In sex and age estimation models, bone density was a significant predictor of sex. Both fusion category and bone density were significant predictors of age group for adult females. This study provides a developmental baseline for understanding hyoid bone fusion and bone density in typically developing individuals. Findings have implications for the disciplines of forensics, anatomy, speech pathology, and anthropology.
Vocal Tract Development Lab, Waisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Rm 427, Madison, WI, 53705-2280, USA.
Ellie
E
Fisher
Vocal Tract Development Lab, Waisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Rm 427, Madison, WI, 53705-2280, USA.
Diane
D
Austin
Vocal Tract Development Lab, Waisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Rm 427, Madison, WI, 53705-2280, USA.
Helen M
HM
Werner
Vocal Tract Development Lab, Waisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Rm 427, Madison, WI, 53705-2280, USA.
Ying Ji
YJ
Chuang
School of Medicine and Public Health, University of Wisconsin-Madison, 1300 University Avenue, Madison, WI, 53706, USA.
Edward
E
Bersu
Vocal Tract Development Lab, Waisman Center, University of Wisconsin-Madison, 1500 Highland Ave, Rm 427, Madison, WI, 53705-2280, USA. vorperian@waisman.wisc.edu.
Houri K
HK
Vorperian
D000293:Adolescent; D000328:Adult; D000365:Age Determination by Skeleton / Q000379:methods*; D000368:Aged; D000369:Aged, 80 and over; D015519:Bone Density / Q000502:physiology*; D002648:Child; D002675:Child, Preschool; D005260:Female; D018732:Forensic Anthropology; D006801:Humans; D006928:Hyoid Bone / Q000000981:diagnostic imaging / Q000254:growth & development*; D021621:Imaging, Three-Dimensional; D007223:Infant; D008297:Male; D008875:Middle Aged; D010012:Osteogenesis / Q000502:physiology*; D054881:Sex Determination by Skeleton / Q000379:methods*; D014057:Tomography, X-Ray Computed; D055815:Young Adult
3D modeling; Bone density; Computed tomography; Forensic science; Hyoid bone fusion; In vivo