Synchronous metastatic skull base chordoma to the breast: case report and literature review.
METHODS
During routine staging work-up for a left breast mass, a 68-year-old woman complained of dysphagia and dysphonia. During further investigations, a left-sided lesion at the foramen magnum was observed on brain imaging. Both lesions were biopsied and showed a classical chordoma.


RESULTS
The skull-base lesion and the breast lesion were surgically resected, and adjuvant radiotherapy was given.


CONCLUSIONS
Chordoma is a rare primary central nervous system tumour that seldom metastasizes. The lung is the most common site of metastasis. Synchronous breast metastasis from a skull-base chordoma is very rare, and a safe management option includes a maximum resection followed by adjuvant radiotherapy.
Department of Radiation Oncology, Jewish General Hospital, McGill University, Montreal, QC;
S I
SI
Shakir
Department of Pathology, Jewish General Hospital, McGill University, Montreal, QC;
M
M
Pelmus
Department of Pathology, Jewish General Hospital, McGill University, Montreal, QC;
A
A
Florea
Department of Surgery, Jewish General Hospital, McGill University, Montreal, QC;
J F
JF
Boileau
Department of Pathology, Montreal Neurological Institute, McGill University, Montreal, QC;
M C
MC
Guiot
Department of Neurosurgery, Jewish General Hospital, McGill University, Montreal, QC.
S
S
Di Maio
Department of Radiation Oncology, Jewish General Hospital, McGill University, Montreal, QC;
T M
TM
Muanza
Chordoma; radiotherapy; surgery; synchronous metastasis