Concise total synthesis of (±)-serotobenine.
A concise total synthesis of (±)-serotobenine via a strategy inspired by the biosynthetic hypothesis for this alkaloid was accomplished. The indolofuran core was constructed by an iron-catalyzed intermolecular oxidative radical cross-coupling reaction developed by our group.
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China. xiachengfeng@mail.kib.ac.cn and University of Chinese Academy of Sciences, Beijing 100049, China.
Kangjiang
K
Liang
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China. xiachengfeng@mail.kib.ac.cn and University of Chinese Academy of Sciences, Beijing 100049, China.
Ting
T
Wu
State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, Yunnan, China. xiachengfeng@mail.kib.ac.cn and Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, Yunnan University, Kunming 650091, China.
Chengfeng
C
Xia
D002384:Catalysis; D060326:Chemistry Techniques, Synthetic; D007211:Indoles / Q000138:chemical synthesis* / Q000737:chemistry*; D007501:Iron / Q000737:chemistry; D013237:Stereoisomerism
D007211:Indoles; C531376:serotobenine; D007501:Iron