Fludarabine, idarubicin, and cytarabine regimen together with TKI followed by haploidentical hematopoietic stem cell transplantation, a success for relapsed Ph+ acute lymphoblastic leukemia.
In this report, a case of relapsed Ph+ ALL was remedied by reinduction, and consolidation regimen of TKI and Flu+ Ara-C+ IDA (FLAI) combination, followed by haploidentical SCT. Results suggest that FLAI together with TKI and subsequently with haploidentical SCT could be applied for relapsed Ph+ ALL.
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Wei
W
Sang
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Ying
Y
Wang
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Cong
C
Zhang
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Dongmei
D
Yan
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Mingshan
M
Niu
Department of Radiology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Chun
C
Yang
Department of Pathology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Xia
X
Liu
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Cai
C
Sun
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Zhe
Z
Zhang
Department of Medicine University of Virginia Cancer Center Charlottesville Virginia.
Thomas P
TP
Loughran
Department of Hematology Affiliated Hospital of Xuzhou Medical College Xuzhou China.
Kailin
K
Xu
Allogeneic hematopoietic stem cell transplantation; Ph+ acute lymphoblastic leukemia; T cells; graft‐versus‐host disease