Pneumocystis Jirovecii Pneumonia in a Patient with Anti-N-Methyl-D-Aspartate Receptor Postherpetic Encephalitis.
Anti-N-methyl-D-aspartate receptor encephalitis is a neuroimmunologic disorder that has been increasingly diagnosed during the past 5 years. It provokes a predictable syndrome treated with several immunomodulatory agents, such as corticosteroids and/or biologics. We managed a child with this disease who developed Pneumocystis jirovecii pneumonia as a direct infectious complication of the use of rituximab.
From the *Pediatric Intensive Care Unit, Department of Pediatrics, Hospital Universitario Donostia, San Sebastián, Spain; and †Microbiology Department, Hospital Universitario Donostia, Biodonostia Institute, Biomedical Research Center Network for Respiratory Diseases (CIBERES), San Sebastián. Spain.
Jorge
J
García-Moreno
Jon
J
Igartua Laraudogoitia
Milagrosa
M
Montes Ros
D060426:Anti-N-Methyl-D-Aspartate Receptor Encephalitis / Q000188:drug therapy* / Q000382:microbiology* / Q000473:pathology / Q000821:virology; D001688:Biological Products / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use; D007223:Infant; D008297:Male; D045363:Pneumocystis carinii / Q000302:isolation & purification*; D011020:Pneumonia, Pneumocystis / Q000188:drug therapy* / Q000473:pathology*; D000069283:Rituximab / Q000009:adverse effects / Q000627:therapeutic use
D001688:Biological Products; D007155:Immunologic Factors; D000069283:Rituximab