Spectral-Statistical Approach for Revealing Latent Regular Structures in DNA Sequence.
Methods of the spectral-statistical approach (2S-approach) for revealing latent periodicity in DNA sequences are described. The results of data analysis in the HeteroGenome database which collects the sequences similar to approximate tandem repeats in the genomes of model organisms are adduced. In consequence of further developing of the spectral-statistical approach, the techniques for recognizing latent profile periodicity are considered. These techniques are basing on extension of the notion of approximate tandem repeat. Examples of correlation of latent profile periodicity revealed in the CDSs with structural-functional properties in the proteins are given.
Institute of Mathematical Problems of Biology, Russian Academy of Sciences, Institutskaya st., 4, 142290, Pushchino, Russia. maramaria@yandex.ru.
Maria
M
Chaley
Department of Computational Mathematics and Mathematical Physics, Moscow State Technical University, n.a. N.E. Bauman the 2nd Baumanskaya st., 5, 105005, Moscow, Russia.
Vladimir
V
Kutyrkin
D019295:Computational Biology; D004247:DNA / Q000737:chemistry* / Q000378:metabolism*; D030541:Databases, Genetic; D006801:Humans; D008957:Models, Genetic; D015233:Models, Statistical; D009690:Nucleic Acid Conformation; D010507:Periodicity; D017422:Sequence Analysis, DNA / Q000379:methods*; D020080:Tandem Repeat Sequences
D004247:DNA
Approximate tandem repeats; CDS; HeteroGenome database; Latent periodicity; Profile periodicity; Spectral–statistical approach