[One-year survival improvement in lung cancer in France. Results of the prospective real life studies KBP-2000-CPHG and KBP-2010-CPHG].
BACKGROUND
The French college of general hospital respiratory physicians (CPHG) has conducted 10 years apart two prospective observational studies to assess changes in the primary lung cancer epidemiology and outcomes, including 1-year mortality.


METHODS
In 2000 and 2010, all volunteer adult patients followed in the respiratory department of general hospitals participating in the study were consecutively included if their lung cancer was histologically or cytologically diagnosed between 01 January and 31 December (sample date). Their vital status at least 1 year after inclusion and date of death (if applicable) were collected.


RESULTS
Respectively, 5667 and 7051 patients were included in the study in 2000 and 2010 and vital status of 5441 (96.0%) and 6981 (99%) patients known. One-year mortality rate was 61.8% in 2000 and 56.4% in 2010 (P<0.0001). Mortality rate significantly decreased from 2000 to 2010 in non-small-cell lung cancer (60.7% vs. 55.2%; P<0.0001) but not in small-cell lung cancer (66.9% vs. 64.2%; P=0.22). The year of diagnosis was an independent risk factor of mortality (OR=0.84; 95% CI: 0.77-0.91; P<0.0001).


CONCLUSIONS
Although it remains low (43.6% in 2010), life expectancy at 1 year for patients with lung cancer has improved in 10 years. Five-year results are expected to show whether this improvement is maintained or not over time.
Service de pneumologie, centre hospitalier de Meaux, 6-8, rue Saint-Fiacre, BP 218, 77104 Meaux cedex, France. Electronic address: m-grivaux@ch-meaux.fr.
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M
Grivaux
Service d'oncologie, centre hospitalier de Montélimar, quartier Beausseret, route de Sauzet, 26216 Montélimar, France.
B
B
Duvert
Service de pneumologie, centre hospitalier de la polynésie française, avenue du Général-de-Gaulle, 98713 Papeete, Polynésie française.
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P
Ferrer-Lopez
Service de pneumologie, centre hospitalier de la Région D'annecy, 1, avenue de l'Hôpital, 74370 Metz-Tessy, France.
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S
Hominal
Service de pneumologie, centre hospitalier de Saint-Malo, 1, rue de la Marne, 35400 Saint-Malo, France.
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E
Goarant
Service de pneumologie, centre hospitalier Victor-Provo, 35, rue de Barbieux, CS 60359, 59056 Roubaix cedex, France.
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A
Brichet-Martin
Service de pneumologie, hôpitaux du Leman, 3, avenue de la Dame, 74200 Thonon-les-Bains, France.
P
P
Romand
Service de pneumologie, polyclinique de Henin-Beaumont, 1110, route de Courrières, 62110 Hénin-Beaumont, France.
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E
Fournier
75116 Paris, France.
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B
Asselain
Service de pneumologie, hôpital Émile-Muller, 20, avenue du Dr-René-Laennec, 68070 Mulhouse, France.
D
D
Debieuvre
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002289:Carcinoma, Non-Small-Cell Lung / Q000401:mortality / Q000628:therapy; D005260:Female; D005602:France / Q000453:epidemiology; D006769:Hospitals, General; D006801:Humans; D008017:Life Expectancy; D008175:Lung Neoplasms / Q000401:mortality* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D058996:Quality Improvement / Q000639:trends; D055752:Small Cell Lung Carcinoma / Q000401:mortality / Q000628:therapy; D012907:Smoking / Q000453:epidemiology; D016019:Survival Analysis
Cancer du poumon; Epidemiology; France; General; Hospital; Hôpitaux généraux; Lung cancer; Mortality; Mortalité; Épidémiologie