Is Serum Uric Acid Level Correlated with Erectile Dysfunction in Coronary Artery Disease Patients?
Coronary artery disease (CAD) and vascular insufficiency are consequences of modern lifestyle, and vasogenic erectile dysfunction (ED) is one of the leading causes of sexual dysfunction which could be prevented like ischemic heart disease if the risk factors are discovered and managed. Seventy-five men scheduled for coronary angiography were asked to fill out the IIEF5 questionnaire and underwent serum lipoprotein-a, uric acid, lipid profile, testosterone, Sex Hormone Binding Globulin (SHBG), dehyderoepiandrostendion sulfate (DHEAS) tests; and the results were compared with those of erectile dysfunction patients with and without coronary artery disease. Ten out of 32 CAD patients (30%) and 6 of 43 normal coronary men had ED Prevalence (P=0.04). The average serum uric acid in ED patients with normal coronary was 5.6 (± 0.68) 6.5 ±078 mg/dl in ED patients of CAD group P=0.034. Men with both ED and CAD had significantly higher levels of lipoprotein-a compared to those CAD patients with normal sexual function. Higher uric acid and lipoprotein-a levels are correlated with the presence of ED in patients with CAD.
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Alborz
A
Salavati
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Abdolrasoul
A
Mehrsai
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farzad
F
Allameh
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farimah
F
Alizadeh
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Farshad
F
Namdari
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Mehdi
M
Hosseinian
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Elaheh
E
Salimi
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Fariba
F
Heidari
Department of Urology, Urology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Gholamreza
G
Pourmand
D000328:Adult; D016022:Case-Control Studies; D017023:Coronary Angiography / Q000379:methods; D003324:Coronary Artery Disease / Q000097:blood*; D007172:Erectile Dysfunction / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012307:Risk Factors; D013739:Testosterone / Q000097:blood; D014527:Uric Acid / Q000097:blood*; D014652:Vascular Diseases / Q000453:epidemiology
D014527:Uric Acid; D013739:Testosterone
Cronary artery disease; Erectile dysfunction; Uric acid