Three-Way Laryngeal Mask Reduces Anesthesia-Related Stress Responses in Bronchoalveolar Lavage: An Experimental Canine Study.
OBJECTIVE
To compare the ventilatory effects of the three-way laryngeal mask airway (TLMA) and tracheal tube (TT) on hemodynamics, respiratory function, and stress responses in a canine model during bronchoalveolar lavage (BAL).


METHODS
Experimental study.


METHODS
The 303rd Hospital of the Chinese People&amp;#039;s Liberation Army in May 2013.


METHODS
Sixteen dogs were divided into two groups. MAP, SpO2 and HR were recorded before anesthesia (T0), immediately before intubation (T1), during intubation (T2), at 3 (T3) and 10 (T4) minutes after mechanical ventilation, at 10 (T5), 20 (T6), and 30 (T7) minutes during the course of BAL, during extubation (T8), and 3 minutes after extubation (T9). Tidal volume, peak inspiratory airway pressure, and expiratory CO2 pressure were recorded at time points T2, T5, T6, T7, and T8. Stress responses variables, including epinephrine and norepinephrine levels, were examined at time points T0, T2, T3, T5, T8, and T9.


RESULTS
BAL was successfully completed in all animals. In comparison to the TT, the TLMA was capable of maintaining hemodynamic stability and ventilation (p &amp;lt; 0.05), and producing less stress responses (p &amp;lt; 0.05).


CONCLUSIONS
In a canine model, ventilation with the TLMA was better than the TT during BAL in terms of maintaining effective ventilation and stable hemodynamics, and producing less stress responses.
Department of Anesthesiology, 303 Hospital of PLA, 52 Zhiwu Road, Nanning 530021, China.
Tian-Ming
TM
Yang
Guangxi Food and Drug Administration, Nanning 530021, Guangxi, China.
Qi-Zhi
QZ
Wei
Department of Respiratory Diseases, 303 Hospital of PLA, 52 Zhiwu Road, Nanning 530021, China.
Wei-Zhong
WZ
Lu
Department of Anesthesiology, 303 Hospital of PLA, 52 Zhiwu Road, Nanning 530021, China.
Xue-Liang
XL
Fan
D000768:Anesthesia, General; D000818:Animals; D001784:Blood Gas Analysis; D018893:Bronchoalveolar Lavage / Q000379:methods*; D001999:Bronchoscopy; D004285:Dogs; D006339:Heart Rate / Q000502:physiology; D006439:Hemodynamics; D007442:Intubation, Intratracheal; D017214:Laryngeal Masks; D012121:Respiration, Artificial / Q000379:methods*; D012129:Respiratory Function Tests; D016896:Treatment Outcome