Letter to the editor in response to the article "Clinical characteristics and risk factors for low dose methotrexate toxicity: a cohort of 28 patients" by Kivity S, Zafrir Y, Loebstein R, Pauzner R, Mouallem M, Mayan H, Autoimmun Rev. 2014 Nov.;13(11):1109-13: Height of MTX-PG levels in low-dose MTX-toxicity differs according to the time of onset.
Department of Hospital Pharmacy, Erasmus MC, Postbus 2040, 3000 CA Rotterdam, The Netherlands; Department of Hospital Pharmacy, Sint Franciscus Gasthuis, Postbus 10900, 3004 BA Rotterdam, The Netherlands.
Sophie
S
Wassenaar
Department of Clinical Chemistry, Erasmus MC, Postbus 2040, 3000 CA Rotterdam, The Netherlands.
Ethan
E
den Boer
Department of Hospital Pharmacy, Sint Franciscus Gasthuis, Postbus 10900, 3004 BA Rotterdam, The Netherlands.
Elsbeth M
EM
Westerman
Department of Rheumatology, Erasmus MC, Postbus 2040, 3000 CA Rotterdam, The Netherlands.
Johanna M
JM
Hazes
Department of Clinical Chemistry, Erasmus MC, Postbus 2040, 3000 CA Rotterdam, The Netherlands. Electronic address: r.dejonge1@vumc.nl.
Robert
R
de Jonge
D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D064420:Drug-Related Side Effects and Adverse Reactions; D006801:Humans; D008727:Methotrexate; D012307:Risk Factors
D008727:Methotrexate