Idiopathic Intracranial Hypertension Induced by Topical Application of Vitamin A.
A 21-year-old nonobese woman developed headaches and papilledema while excessively using 3 topical preparations of vitamin A. Neuroimaging studies were unremarkable and opening pressure on lumbar puncture was 300 mm H2O with normal cerebrospinal fluid composition. After discontinuation of the topical vitamin A preparations, the symptoms and signs of increased intracranial pressure resolved. The association of intracranial hypertension and topical vitamin A application has only been reported once previously.
Department of Internal Medicine, King Saud University, Riyadh, Saudi Arabia.
Yousef M
YM
Mohammad
Ismail R
IR
Raslan
Fawaz A
FA
Al-Hussain
D000287:Administration, Topical; D005260:Female; D006801:Humans; D007427:Intracranial Pressure / Q000187:drug effects*; D010211:Papilledema / Q000175:diagnosis / Q000209:etiology; D011559:Pseudotumor Cerebri / Q000139:chemically induced* / Q000150:complications / Q000175:diagnosis; D014801:Vitamin A / Q000008:administration & dosage / Q000009:adverse effects*; D014815:Vitamins / Q000008:administration & dosage / Q000009:adverse effects; D055815:Young Adult
D014815:Vitamins; D014801:Vitamin A