Human Interleukin-2 and Hen Egg White Lysozyme: Screening for Bacteriolytic Activity against Various Bacterial Cells.
The bacteriolytic activity of interleukin-2 and hen egg white lysozyme against 34 different species of microorganisms has been studied. It was found that 6 species of microorganisms are lysed in the presence of interleukin-2. All interleukin-2-sensitive microorganisms belong either to the Enterobacteriaceae, Bacillaceae, or the Lactobacillaceae family. It was also found that 12 species of microorganisms are lysed in the presence of lysozyme, and 16 species of microorganisms are lysed in the presence of sodium dodecyl sulfate (SDS). The bacteriolytic activity of interleukin-2 and lysozyme was studied at various pH values.
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Levashov
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Ovchinnikova
Clinical Center, I.M. Sechenov First Moscow State Medical University, Bolshaya Pirogovskaya St., 2 -4, 119881, Moscow, Russian Federation.
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Morozova
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Matolygina
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Osipova
Department of Microbiology, Faculty of Biology, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-12, 119991, Moscow, Russian Federation.
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Cherdyntseva
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Savin
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation ; A.N. Bach Institute of Biochemistry, Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninsky Pr., 33-2, 119071, Moscow, Russian Federation.
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Zakharova
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation ; A.N. Bach Institute of Biochemistry, Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninsky Pr., 33-2, 119071, Moscow, Russian Federation.
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Alekseeva
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Belogurova
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Smirnov
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation ; A.N. Bach Institute of Biochemistry, Federal Research Centre "Fundamentals of Biotechnology" of the Russian Academy of Sciences, Leninsky Pr., 33-2, 119071, Moscow, Russian Federation.
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Tishkov
Department of Chemical Enzymology, Faculty of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory, 1-3, 119991, Moscow, Russian Federation.
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Levashov
bacteriolytic activity; interleukin-2; lysozyme