Two-stage protocol and spacer implantation in the treatment of destructive septic arthritis of the hip joint.
BACKGROUND
The ideal treatment of the destructive septic arthritis of the hip joint remains controversial. The aim of the present retrospective study was to report on our experience about the use of antibiotic-loaded cement spacers in the treatment of destructive bacterial coxitis.


METHODS
22 consecutive patients (11 male, 11 female, mean age 59.7 years) have been treated with a two-stage protocol and implantation of an antibiotic-loaded cement spacer. All patients' records have been retrospectively evaluated with regard to comorbidities/predisposing factors, infection cause, causative pathogen organism, presence of a psoas abscess, surgical time of spacer implantation, duration of spacer implantation, spacer articulation, impregnation of bone cement, systemic antibiotic therapy, surgical time of prosthesis implantation, implant type, complications, and infection control rate.


RESULTS
The most common identified organism was Staphylococcus aureus (73 %). The mean duration of spacer implantation was 88 days. Spacer-specific complications were observed in 23 % of the cases and spacer non-specific ones in 50 % between stages. The mortality rate after the first stage was 18 %. Prosthesis implantation was performed in 16 cases. At a mean follow-up of 44.8 (12-120) months, the primary infection control rate (after one spacer implantation) was 87 % (13/15) and the secondary infection control rate (after two spacer implantations) 100 %.


CONCLUSIONS
Two-stage treatment and spacer implantation is associated with a high rate of infection control but also with a high mortality rate between stages.
Klinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes, Kirrbergerstr. 100, 66421, Homburg, Saar, Germany. k.anagnostakos@web.de.
Konstantinos
K
Anagnostakos
Klinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes, Kirrbergerstr. 100, 66421, Homburg, Saar, Germany.
Luise
L
Duchow
Klinik für Orthopädie und Orthopädische Chirurgie, Universitätsklinikum des Saarlandes, Kirrbergerstr. 100, 66421, Homburg, Saar, Germany.
Katrin
K
Koch
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001170:Arthritis, Infectious / Q000150:complications / Q000401:mortality / Q000601:surgery*; D001843:Bone Cements / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D006621:Hip Joint / Q000382:microbiology / Q000601:surgery*; D006801:Humans; D007595:Joint Prosthesis / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D019637:Orthopedic Procedures / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D016459:Prosthesis-Related Infections / Q000601:surgery; D012189:Retrospective Studies; D013203:Staphylococcal Infections / Q000150:complications / Q000601:surgery; D013211:Staphylococcus aureus
D000900:Anti-Bacterial Agents; D001843:Bone Cements
Cement spacer; Coxitis; Hip spacer; Mortality; Septic arthritis