Efficacy of Positron Emission Tomography/Computed Tomography in Gastric Mucosa-associated Lymphoid Tissue Lymphoma.
OBJECTIVE
This study evaluated the diagnostic efficacy of fluorine-18 fluorodeoxyglucose PET/CT (F-18 FDG PET/CT) for patients with gastric mucosa-associated lymphoid tissue (MALT) lymphoma and examined the association between FDG avidity and the clinical factors affecting lesions.


METHODS
Among the patients diagnosed with gastric MALT lymphoma, 16 who underwent a PET/CT for gastric MALT lymphoma were semi-quantitatively and qualitatively tested for FDG avidity of lesions in the stomach. Retrospectively collected data was analyzed to investigate the clinicoradiological factors and endoscopic findings between the patients with positive F-18 FDG PET/CT scans and those with negative scans.


RESULTS
Eight of the 16 patients showed FDG avidity. When comparing the size of lesions in the stomach, the patients with FDG avidity had significantly larger lesions than those without (28.8 mm vs. 15.0 mm, p=0.03). The FDG-avid group has a significantly higher rate of positive CT scans than the non-avid group (75% vs. 13%, p=0.03). According to the endoscopic finding of the lesions, FDG avidity was pronounced with 75% of the protruding tumors, and 100% of the erosive-ulcerative types, which are a type of depressed tumors.


CONCLUSIONS
When gastric MALT lymphoma is large, when lesions are found using abdominal CT scans, and the macroscopic appearance of a lesion is that of a protruding tumor or erosive-ulcerative type of depressed tumor, there is a high probability that such patients may have a positive F-18 FDG PET/CT scan.
Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Jin Won
JW
Hwang
Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Sam Ryong
SR
Jee
Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Sang Heon
SH
Lee
Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Ji Hyun
JH
Kim
Department of Internal Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Sang Yong
SY
Seol
Department of Nuclear Medicine, Busan Paik Hospital, Inje University College of Medicine, Busan, Korea.
Seok Mo
SM
Lee
D000368:Aged; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000737:chemistry / Q000378:metabolism; D005773:Gastroscopy; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000000981:diagnostic imaging; D008297:Male; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography; D012189:Retrospective Studies; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging / Q000378:metabolism
D019788:Fluorodeoxyglucose F18
Lymphoma, B-cell, marginal zone; Positron emission tomography; Stomach