Precision medicine and oncology: an overview of the opportunities presented by next-generation sequencing and big data and the challenges posed to conventional drug development and regulatory approval pathways.
Genentech, Inc., South San Francisco, USA doherty.michael@gene.com.
M
M
Doherty
F. Hoffmann-La Roche, Basel, Switzerland.
T
T
Metcalfe
Genentech, Inc., South San Francisco, USA.
E
E
Guardino
Genentech, Inc., South San Francisco, USA.
E
E
Peters
F. Hoffmann-La Roche, Basel, Switzerland.
L
L
Ramage
D003627:Data Interpretation, Statistical; D017277:Drug Approval / Q000379:methods*; D055808:Drug Discovery / Q000379:methods* / Q000639:trends; D059014:High-Throughput Nucleotide Sequencing / Q000379:methods* / Q000639:trends; D006801:Humans; D008495:Medical Oncology / Q000379:methods* / Q000639:trends; D009369:Neoplasms / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D057285:Precision Medicine / Q000379:methods* / Q000639:trends