Adding Sufentanil to TAP Block Hyperbaric Bupivacaine Decreases Post-Cesarean Delivery Morphine Consumption.
Pain management is crucially important in the postoperative period as it increases patient comfort and satisfaction. The primary outcome of present study was to evaluate the effect of sufentanil added to hyperbaric bupivacaine solution 0.25% in transversus abdominis plane (TAP) block, on postoperative analgesic consumption. Fifty ASA physical status I-II term primiparous single-tone pregnant women aged 20-40 years scheduled for elective cesarean delivery with Pfannenstiel incision under general anaesthesia were enrolled in this randomized, double-blind, placebo-controlled trial. Ultrasound guided TAP block was performed at the end of surgery. Patients were randomly enrolled into two groups. Patients in the study group received 20 ml of hyperbaric bupivacaine 0.25% plus 1mL of sufentanil on either side while patients in the placebo group were administered 20 ml of hyperbaric bupivacaine 0.25% along with 1mL of placebo. Post-cesarean delivery visual analogue scale (VAS) for pain and morphine usage were measured and recorded. The morphine consumption was significantly less in the study group (37.2 ± 16.1 mg) than the control group (52.8 ± 16.7 mg, P =0.002).The VAS for pain both in rest and coughing were same in groups. Sufentanil added to 0.25% hyperbaric bupivacaine in TAP block decreases post cesarean delivery morphine consumption.
Department of Obstetrics & Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Laleh
L
Eslamian
Department of Obstetrics & Gynecology Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Motahareh
M
Kabiri-Nasab
Department of Obstetrics & Gynecology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Marzieh
M
Agha-Husseini
Department of Anesthesiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Omid
O
Azimaraghi
Department of Anesthesiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Gilda
G
Barzin
Department of Anesthesiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Ali
A
Movafegh
D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage; D000768:Anesthesia, General / Q000379:methods; D000779:Anesthetics, Local / Q000008:administration & dosage; D002045:Bupivacaine / Q000008:administration & dosage*; D002585:Cesarean Section / Q000379:methods; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D009020:Morphine / Q000008:administration & dosage*; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement; D010149:Postoperative Pain / Q000188:drug therapy; D011247:Pregnancy; D017409:Sufentanil / Q000008:administration & dosage*; D055815:Young Adult
D000701:Analgesics, Opioid; D000779:Anesthetics, Local; D009020:Morphine; D017409:Sufentanil; D002045:Bupivacaine
Analgesia; Cesarean delivery; Pain intensity; TAP block