A large outbreak of Japanese encephalitis predominantly among adults in northern region of West Bengal, India.
Unusual rise of acute encephalitis syndrome cases (AES) were reported in July 2014 in the northern region of West Bengal, India. Investigations were carried out to characterize the outbreak and to identify the associated virus etiology. This observational study is based on 398 line listed AES cases, mostly (70.8%, 282/398) adults, with case fatality ratio of 28.9% (115/398). Japanese encephalitis virus infection was detected in 134 (49.4%) among 271 AES cases tested and most of them (79.1%, 106/134) were adults. The study reports a large outbreak of genotype III Japanese encephalitis among adults in northern region of West Bengal, India. J. Med. Virol. 88:2004-2011, 2016. © 2016 Wiley Periodicals, Inc.
Epidemiology Group, National Institute of Virology, Pune, India.
Yogesh K
YK
Gurav
Encephalitis Group, National Institute of Virology, Pune, India.
Vijay P
VP
Bondre
Epidemiology Group, National Institute of Virology, Pune, India.
Babasaheb V
BV
Tandale
Encephalitis Group, National Institute of Virology, Pune, India.
Rekha G
RG
Damle
Department of Microbiology, North Bengal Medical College, Siliguri, Darjeeling, West Bengal, India.
Sanjay
S
Mallick
Department of Medicine, North Bengal Medical College, Siliguri, Darjeeling, West Bengal, India.
Uday S
US
Ghosh
Department of Paediatric, North Bengal Medical College, Siliguri, Darjeeling, West Bengal, India.
Shankha S
SS
Nag
D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D002648:Child; D004196:Disease Outbreaks; D004664:Encephalitis Virus, Japanese / Q000235:genetics / Q000302:isolation & purification; D004672:Encephalitis, Japanese / Q000453:epidemiology* / Q000401:mortality / Q000821:virology; D005260:Female; D005838:Genotype; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D055815:Young Adult
Acute encephalitis syndrome; Eastern India; Japanese encephalitis virus; adults; disease outbreak; genotype II