Fiber Optic Surface Plasmon Resonance-Based Biosensor Technique: Fabrication, Advancement, and Application.
Fiber optic-based biosensors with surface plasmon resonance (SPR) technology are advanced label-free optical biosensing methods. They have brought tremendous progress in the sensing of various chemical and biological species. This review summarizes four sensing configurations (prism, grating, waveguide, and fiber optic) with two ways, attenuated total reflection (ATR) and diffraction, to excite the surface plasmons. Meanwhile, the designs of different probes (U-bent, tapered, and other probes) are also described. Finally, four major types of biosensors, immunosensor, DNA biosensor, enzyme biosensor, and living cell biosensor, are discussed in detail for their sensing principles and applications. Future prospects of fiber optic-based SPR sensor technology are discussed.
a College of Chemistry, Sichuan University , Chengdu , China.
Gaoling
G
Liang
b Research Center of Analytical Instrumentation, Key Laboratory of Bio-resource and Eco-environment, Sichuan University , Chengdu , China.
Zewei
Z
Luo
a College of Chemistry, Sichuan University , Chengdu , China.|c Faculty of Biotechnology Industry, Chengdu University , Chengdu , China.
Kunping
K
Liu
b Research Center of Analytical Instrumentation, Key Laboratory of Bio-resource and Eco-environment, Sichuan University , Chengdu , China.
Yimin
Y
Wang
d Analytical and Testing Center, Sichuan University , Chengdu , China.
Jianxiong
J
Dai
b Research Center of Analytical Instrumentation, Key Laboratory of Bio-resource and Eco-environment, Sichuan University , Chengdu , China.
Yixiang
Y
Duan
D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods*; D005336:Fiber Optic Technology; D006801:Humans; D055100:Optical Fibers; D020349:Surface Plasmon Resonance
Fiber optic biosensor; localized surface plasmon resonance (LSPR); probe geometry; surface plasmons