Headache in Caucasian patients with Moyamoya angiopathy - a systematic cohort study.
Background Headache is common in patients with Moyanoya angiopathy (MMA), but usually underestimated in its management and not well characterized. Methods A validated self-administered headache screening questionnaire and a telephone interview were used in order to investigate headache characteristics, frequency and pain intensity in a large cohort of 55 German patients with MMA. Results Thirty-seven patients (67.3%) had suffered from headache in the past year. Headache intensity was rated 3.2 ± 1.3 on a verbal rating scale from 0 to 10. Seventeen patients (47.9%) reported migraine-like headache, 10 patients (27.0%) reported tension type-like headache and 10 patients (27.0%) had a combination of both. The majority of patients with migraine-like headache ( n = 10, 58.8%) described migrainous aura. Headache frequency and intensity improved significantly after revascularization surgery; however, nine patients developed new-onset headache postoperatively. Conclusion Headache is very common in MMA, often with a migraine-like phenotype. Tension type-like headache was also found in 27% of patients, which is a new finding that has not been reported before.
1 Department of Neurology, Alfried-Krupp-Hospital Essen, Germany.
Markus
M
Kraemer
1 Department of Neurology, Alfried-Krupp-Hospital Essen, Germany.
Sie-In
SI
Lee
2 Department of Neurology, St. Josef Hospital, Ruhr University of Bochum, Bochum, Germany.
Ilya
I
Ayzenberg
1 Department of Neurology, Alfried-Krupp-Hospital Essen, Germany.
Jan Claudius
JC
Schwitalla
1 Department of Neurology, Alfried-Krupp-Hospital Essen, Germany.
Rolf R
RR
Diehl
1 Department of Neurology, Alfried-Krupp-Hospital Essen, Germany.
Peter
P
Berlit
3 Department of Neurology and Headache Center, University Hospital Essen, University of Duisburg-Essen, Germany.
Bert
B
Bosche
4 Department of Neurology, Evangelic Hospital Unna, Germany.
Zaza
Z
Katsarava
3 Department of Neurology and Headache Center, University Hospital Essen, University of Duisburg-Essen, Germany.|5 Center for Neurology, Asklepios Hospitals Schildautal, Seesen, Germany.
Mark
M
Obermann
D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D006261:Headache / Q000175:diagnosis* / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009072:Moyamoya Disease / Q000175:diagnosis* / Q000453:epidemiology*; D012189:Retrospective Studies; D044465:White People; D055815:Young Adult
Moyamoya angiopathy; aura; bypass intervention; headache; migraine like; tension type-like headache