Ligation of the mesovarium in dogs with a self-locking implant of a resorbable polyglycolic based co-polymer: a study of feasibility and comparison to suture ligation.
BACKGROUND
Ligation of the mesovarium in female dogs may be cumbersome with risk of complications and is associated with intense noxious stimuli. A resorbable implant, a self-locking loop designed for surgery, was developed as an alternative to traditional ligation. The study aimed to test the feasibility of ligating the canine ovarian pedicle with the implant and to compare its performance to traditional suture ligation.


RESULTS
In total 45 intact female dogs destined for elective ovariohysterectomy and adoption were included. In 21 dogs the new resorbable implant was used to ligate the mesovarium, and in 24 control dogs traditional suture was used with one encircling ligature. Mean weight of implant dogs was 10.7 ± 5.6 kg (range 3.5-22.0), and mean weight of control dogs was 12.8 ± 6.4 kg, (range 4.1-27.0). The body weight of dogs did not differ between groups (P = 0.25). In total, 42 ovarian pedicles were successfully ligated with the implant. In one control dog, intraoperative haemorrhage from the left ovarian pedicle was diagnosed. The mesovarium was re-ligated and haemostasis was confirmed. All dogs recovered uneventfully. The ligation time of the mesovarium was significantly shortened (P = 0.02) by using the self-locking implant versus a single ligature (3'28'' ± 1'05'' and 5'29'' ± 3'54'', respectively). Total duration of surgery differed between the groups (P = 0.02) with a shortened duration of surgery when using the self-locking implant (15'56'' ± 2'47'' and 20'39'' ± 8'58'', study group versus control group, respectively). In both groups, duration of surgery and time required to ligate the ovarian pedicle were longer in larger dogs than smaller dogs.


CONCLUSIONS
The results of this feasibility study suggested the implant can be used to ligate the canine mesovarium. Compared with traditional suture ligation, the results suggested that time to ligate the ovarian pedicle and duration of surgery were significantly reduced with the implant. More time was required to perform surgeries in larger dogs.
Department of Animal Clinical and Surgery, Universidade Estadual Norte Fluminense, UENF/RJ, Av. Alberto Lamego, 2000, Campos dos Goytacazes, RJ, Brazil.
Matheus Roberto da Mota
http://orcid.org/0000-0001-5040-9654
MR
Costa
Department of Animal Clinical and Surgery, Universidade Estadual Norte Fluminense, UENF/RJ, Av. Alberto Lamego, 2000, Campos dos Goytacazes, RJ, Brazil.
André Lacerda de Abreu
AL
Oliveira
Department of Veterinary Surgery and Anaesthesia, Universidade Iguaçu, UNIG/RJ, BR-356/KM 02, Itaperuna, RJ, Brazil.
Renato Moran
RM
Ramos
Department of Animal Clinical and Surgery, Universidade Estadual Norte Fluminense, UENF/RJ, Av. Alberto Lamego, 2000, Campos dos Goytacazes, RJ, Brazil.
Leonardo Waldstein de Moura
LW
Vidal
Resorbable Devices AB, Ormvråksvägen 15, SE-756 52, Uppsala, Sweden.
Niklas
http://orcid.org/0000-0003-4957-3056
N
Borg
Resorbable Devices AB, Ormvråksvägen 15, SE-756 52, Uppsala, Sweden. Odd.Hoglund@slu.se.|Department of Clinical Sciences, Swedish University of Agricultural Sciences, Box 7054, SE-750 07, Uppsala, Sweden. Odd.Hoglund@slu.se.
Odd V
http://orcid.org/0000-0003-0978-836X
OV
Höglund
D020341:Absorbable Implants / Q000662:veterinary*; D000818:Animals; D004285:Dogs; D017558:Elective Surgical Procedures / Q000379:methods / Q000662:veterinary; D005240:Feasibility Studies; D005260:Female; D007044:Hysterectomy / Q000662:veterinary; D008026:Ligation / Q000295:instrumentation / Q000379:methods / Q000662:veterinary; D010052:Ovariectomy / Q000662:veterinary; D010053:Ovary / Q000601:surgery*; D011100:Polyglycolic Acid / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry*; D011446:Prospective Studies; D019736:Prostheses and Implants / Q000662:veterinary*; D015203:Reproducibility of Results; D013537:Sutures; D013997:Time Factors
D011108:Polymers; D011100:Polyglycolic Acid
Canine; Glycolide; Medical device; Ovarian pedicle; Ovariohysterectomy; Spay; Trimethylene carbonate