Incidence and Trend of Liver Cancer in Iran.
OBJECTIVE
To determine incidence and trend of the liver cancer in Iran.


METHODS
An observational study.


METHODS
The Cancer Registry System in Iran, from 2003 to 2009.


METHODS
Crude incidence rate for liver cancer were calculated per 100,000 people. Age standardized incidence rates (ASRs) were estimated using direct standardization and the standard population of World Health Organization (WHO). Data was analyzed using Cochran-Armitage test for linear trend and software of WinPepi 2.1.


RESULTS
Of 3,584 cases of liver cancer recorded between 2003 and 2009, 2,224 and 1,360 cases were men and women, respectively, which revealed significantly increasing trends (p=0.001). The highest incidence rate (950 cases) occurred in 2007 and the lowest rate (256 cases) in 2003. Based on the result, liver cancer incidence was more in men compared to women and the incidence increased with age.


CONCLUSIONS
According to this study, the trend of age-standardized incidence rate of liver cancer in Iran is rising. Hence to prevent and control this cancer, it is necessary to investigate the related risk factors and implement prevention programs in Iran.
Department of Epidemiology, Tabriz University of Medical Sciences, Tabriz, Iran.
Maryam
M
Mirzaei
Department of Epidemiology and Biostatistics, Hamadan University of Medical Sciences, Hamadan, Iran.
Mahshid
M
Ghoncheh
Pregnancy Health Research Center, Zahedan University of Medical Sciences, Zahedan, Iran.
Zahra
Z
Pournamdar
Minimally Invasive Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Fahimeh
F
Soheilipour
Epidemiology and Biostatistics, Tehran University of Medical Sciences, Tehran, Iran.
Hamid
H
Salehiniya
D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D015994:Incidence; D007492:Iran / Q000453:epidemiology; D008113:Liver Neoplasms / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D008875:Middle Aged; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors; D017678:Sex Distribution; D014944:World Health Organization; D055815:Young Adult