Dabigatran in the Treatment of Warfarin-Induced Skin Necrosis: A New Hope.
Warfarin-induced skin necrosis is an infrequent and well-recognized complication of warfarin treatment. The incidence was estimated between 0.01% and 0.1% whereas a paradoxal prothrombotic state that arises from warfarin therapy seems to be responsible for this life-threatening disease. To the best of our knowledge we present the first case of an old woman diagnosed with warfarin-induced skin necrosis, in whom novel oral anticoagulants and extensive surgical debridement were combined safely with excellent results.
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Christos
C
Bakoyiannis
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Georgios
G
Karaolanis
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Nikolaos
N
Patelis
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Anastasios
A
Maskanakis
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Georgios
G
Tsaples
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Christos
C
Klonaris
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Sotirios
S
Georgopoulos
1st Department of Surgery, Vascular Surgery Unit, Laikon General Hospital, Medical School of Athens, Agiou Thoma 17, 11527 Athens, Greece.
Theodoros
T
Liakakos