Adipose derived stem cells for regenerative therapy in osteoarticular diseases.
In the recent years, adipose derived stem cells (ASCs) led to significant findings in the field of regenerative therapy. ASCs have various biological properties and capacity as differentiation in three lineages (chondrocytes, osteocytes and adipocytes) or immunomodulation by releasing paracrine factors. Osteoarthritis (OA) is the most frequent osteoarticular disease characterized by none curative treatment. We reviewed all current data on the proof of concept of ASCs in OA pathophysiology as well as an inventory of ASC promising cell therapy in OA.
Yves-Marie
YM
Pers
Christian
C
Jorgensen
D017667:Adipocytes / Q000166:cytology*; D001847:Bone Diseases / Q000628:therapy*; D006801:Humans; D007592:Joint Diseases / Q000628:therapy*; D044968:Regenerative Medicine; D033581:Stem Cell Transplantation / Q000379:methods*; D013234:Stem Cells / Q000166:cytology*