A highly stable and versatile heterobifunctional fluoroalkylation reagent for preparation of fluorinated organic compounds.
A highly stable heterobifunctional fluoroalkylation reagent, 1-azido-2-chloro-1,1,2-trifluoro-2-iodoethane (ACTI) has been prepared in high yield for the first time by a new method. Moreover, the reactivity of both the azido group and the iodine atom of the reagent was systematically investigated and the results demonstrate that this compound is a very versatile and useful new fluoroalkylation reagent for preparation of fluorinated organic compounds.
CAS Key Laboratory of Soft Matter Chemistry and Department of Polymer Science and Engineering, University of Science and Technology of China, Jinzhai Road 96, Hefei, Anhui Province, People's Republic of China. bairk@ustc.edu.cn.
Jingwen
J
Dai
CAS Key Laboratory of Soft Matter Chemistry and Department of Polymer Science and Engineering, University of Science and Technology of China, Jinzhai Road 96, Hefei, Anhui Province, People's Republic of China. bairk@ustc.edu.cn.
Zili
Z
Li
CAS Key Laboratory of Soft Matter Chemistry and Department of Polymer Science and Engineering, University of Science and Technology of China, Jinzhai Road 96, Hefei, Anhui Province, People's Republic of China. bairk@ustc.edu.cn.
Taisheng
T
Wang
CAS Key Laboratory of Soft Matter Chemistry and Department of Polymer Science and Engineering, University of Science and Technology of China, Jinzhai Road 96, Hefei, Anhui Province, People's Republic of China. bairk@ustc.edu.cn.
Ruke
R
Bai