Expanding Our Understanding of Human Skin Aging.
Two very different studies expand our understanding of human skin aging. In the first study, Hüls et al. show an association between nitrogen dioxide levels in outdoor air and number of lentigines on the cheek. In the second study, Bowman and Birch-Machin show that mitochondrial complex II activity in human skin fibroblasts decreases with age.
Stanford University School of Medicine, Redwood City, California, USA. Electronic address: alschang@stanford.edu.
Anne Lynn S
ALS
Chang
D002478:Cells, Cultured; D032882:Comprehension; D004787:Environmental Pollution / Q000009:adverse effects*; D005347:Fibroblasts / Q000166:cytology*; D006801:Humans; D007911:Lentigo / Q000209:etiology* / Q000503:physiopathology; D024101:Mitochondrial Proteins / Q000096:biosynthesis; D009585:Nitrogen Dioxide / Q000009:adverse effects; D010085:Oxidative Phosphorylation; D018384:Oxidative Stress / Q000502:physiology*; D012680:Sensitivity and Specificity; D015595:Skin Aging / Q000473:pathology*
D024101:Mitochondrial Proteins; D009585:Nitrogen Dioxide