Prostatic Artery Embolization Using Embosphere Microspheres for Prostates Measuring 80-150 cm(3): Early Results from a US Trial.
Between November 2014 and October 2015, 12 patients with prostates measuring 80-150 cm(3) and lower urinary tract symptoms (LUTSs) were enrolled in a prospective single-center US trial to evaluate Embosphere Microspheres for use in prostatic artery embolization (PAE). At 3 months, mean improvements in International Prostate Symptom Score and quality of life score were 18.3 points (range, 5-27) and 3.6 points (range, 1-6), respectively. One-month cystoscopies and anoscopies demonstrated no ischemic injuries. There were no major complications. In this cohort, Embosphere Microspheres, when used for PAE, were safe and effective in reducing LUTSs in the early follow-up period.
Department of Radiology, University of North Carolina, 101 Manning Dr., Chapel Hill, NC 27514. Electronic address: ari_isaacson@med.unc.edu.
Ari J
AJ
Isaacson
Department of Urology, University of North Carolina, 101 Manning Dr., Chapel Hill, NC 27514.
Mathew C
MC
Raynor
Department of Radiology, University of North Carolina, 101 Manning Dr., Chapel Hill, NC 27514.
Hyeon
H
Yu
Department of Radiology, University of North Carolina, 101 Manning Dr., Chapel Hill, NC 27514.
Charles T
CT
Burke
D000180:Acrylic Resins / Q000008:administration & dosage* / Q000009:adverse effects; D000368:Aged; D015901:Angiography, Digital Subtraction; D000072226:Computed Tomography Angiography; D003558:Cystoscopy; D004621:Embolization, Therapeutic / Q000379:methods*; D005780:Gelatin / Q000008:administration & dosage* / Q000009:adverse effects; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology; D008297:Male; D009657:North Carolina; D011446:Prospective Studies; D011470:Prostatic Hyperplasia / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D011788:Quality of Life; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome
D000180:Acrylic Resins; C496735:trisacryl gelatin microspheres; D005780:Gelatin