Rapid analysis of six trace trichlorophenols in seawater by magnetic micro-solid-phase extraction and liquid chromatography with tandem mass spectrometry.
A new facile, rapid, inexpensive, and sensitive method for the analysis of six trace trichlorophenols in seawater samples was developed by magnetic micro-solid-phase extraction coupled to liquid chromatography with tandem mass spectrometry. Core-shell covalently functionalized ferroferric oxide coated with aminated silicon dioxide and decorated with multiwalled carbon nanotubes was applied as an adsorbent to perform the extraction process. The effect of factors including solution pH, contact time, adsorbent amount, and ionic strength were investigated in detail. The obtained results revealed that the proposed adsorbent was a highly effective and low-cost magnetic micro-solid-phase extraction material for the enrichment of 2,3,4-trichlorophenol, 2,3,5-trichlorophenol, 2,3,6-trichlorophenol, 2,4,5-trichlorophenol, 2,4,6-trichlorophenol, and 3,4,5-trichlorophenol from seawater. Under the optimized conditions, the recoveries ranged from 88.0 to 99.5% at the three spiking levels, the limits of detection and the limits of quantification were 0.002 and 0.007 μg/L for the six trichlorophenols, respectively. The intra- and interday relative standard deviations were 2.0-6.7 and 4.5-8.9%, respectively. The calibration curves showed a good linearity in the range of 0.02-5.0 μg/L. The routine run analyses showed that the developed method was fast, simple, accurate, solvent-saving and high resolution, and it was suitable for the determination of trace trichlorophenols in seawater.
College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou, China.
Mei-Lan
ML
Chen
College of Biology and Environmental Engineering, Zhejiang Shuren University, Hangzhou, China.
Jian-Qing
JQ
Min
School of Environmental Science and Engineering, Zhejiang Gongshang University, Hangzhou, China.
Mei-Qiang
MQ
Cai
Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, China.|Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Sheng-Dong
SD
Pan
Key Laboratory of Health Risk Appraisal for Trace Toxic Chemicals of Zhejiang Province, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, Zhejiang, China.|Ningbo Key Laboratory of Poison Research and Control, Ningbo Municipal Center for Disease Control and Prevention, Ningbo, China.
Mi-Cong
MC
Jin
Ionic strength; Liquid chromatography with tandem mass spectrometry; Magnetic micro-solid phase extraction; Seawater; Trichlorophenols