Complete genome sequence of Bacillus amyloliquefaciens B15 isolated from grape skin, a strain of strong inhibitory activity against fungi.
Bacillus amyloliquefaciens B15 is a Gram-positive, plant-associated bacterium which shows strong antifungal activity, isolated from grape skin in Xinjiang, China. The genome of B. amyloliquefaciens B15 comprises a 4,006,754bp long circular chromosome containing 3991 protein coding genes and 109 RNA genes. Based on genomic analysis, we identified the giant gene clusters, nonribosomal peptidesynthetases (NRPS), and polyketide synthases (PKS), responsible for the biosynthesis of numerous bioactive metabolites. In addition, several functionally related genes, such as TasA, were also been identified for the antagonistic effect on pathogenic fungi but has no effect on the growth of itself.
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China.
Yinzhuo
Y
Yan
College of Life Science and Technology, Guangxi University, Nanning, 530004 Guangxi, China.
Shiyu
S
Liu
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China.
Deliang
D
Wang
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China.
Jie
J
Xue
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China.
Danyang
D
Guo
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China.
Xulei
X
Song
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China.
Fengjie
F
Zhang
College of Life Science and Technology, Guangxi University, Nanning, 530004 Guangxi, China.
Shihai
S
Huang
The Department of Traditional Fermentation Engineering (Brewing), China National Research Institute of Food and Fermentation Industries, 100015 Beijing, China. Electronic address: chunguangluan@163.com.
Chunguang
C
Luan
D000935:Antifungal Agents / Q000378:metabolism* / Q000494:pharmacology; D000069977:Bacillus amyloliquefaciens / Q000737:chemistry / Q000235:genetics*; D005658:Fungi / Q000187:drug effects; D005798:Genes, Bacterial / Q000235:genetics; D016680:Genome, Bacterial / Q000235:genetics*; D005810:Multigene Family / Q000235:genetics; D027843:Vitis / Q000382:microbiology*
D000935:Antifungal Agents
Antifungal; Bacillus amyloliquefaciens B15; Genome sequencing; Lipopeptides; TasA gene