An Epigenetic Clock Measures Accelerated Aging in Treated HIV Infection.
In this issue of Molecular Cell, Gross et al. (2016) find a CpG DNA methylation signature in blood cells of patients with chronic well-controlled HIV infection that correlates with accelerated aging.
Division of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA.
Konstantinos
K
Boulias
Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA.
Judy
J
Lieberman
Division of Newborn Medicine, Boston Children's Hospital, Boston, MA 02115, USA; Department of Pediatrics, Harvard Medical School, Boston, MA 02115, USA. Electronic address: eric.greer@childrens.harvard.edu.
Eric Lieberman
EL
Greer
D000375:Aging / Q000235:genetics; D018899:CpG Islands; D019175:DNA Methylation; D044127:Epigenesis, Genetic; D057890:Epigenomics; D015658:HIV Infections / Q000235:genetics*; D006801:Humans