Outcomes of Women Treated for Popliteal Artery Aneurysms.
BACKGROUND
Popliteal artery aneurysms (PAAs) in women are rare and their outcomes compared with men with PAA are unknown. The purpose of this study was to compare the surgical outcomes of PAA of women with men.


METHODS
All patients who underwent PAA repair at a single institution from 1985 to 2013 were reviewed. All women with degenerative PAA treated during that time frame were matched on year of repair to men. Presentation, mode of repair, and outcomes were reviewed. Survival and amputation-free survival were evaluated by life table analysis.


RESULTS
During the study interval, 8 women with degenerative PAA underwent surgical treatment (1.6% of 485 total PAA repairs). The overall median follow-up was 5 years (range 1 month to 19 years), but the median follow-up was shorter for women than men (1.6 vs. 6 years, P = 0.04). At the time of repair, women were of similar age compared with men (73.5 vs. 71.7 years) and had similar aneurysm size (2.7 vs. 2.9 cm). Women had similar urgency (25 vs. 17.5% emergent) and symptomatic status (50% vs. 55% acute) even though 7 of the 8 women had a thrombosed PAA at the time of repair. Operative time, approach, graft type, and inflow and outflow sources were similar between genders. No women received endovascular repair (0% vs. 10%, P = 0.5). One patient of each gender underwent major amputation (one woman on post-operative day 158 and one man on post-operative day 3). Overall, women had lower survival and amputation-free survival at 2 years (51% vs. 100% and 20% vs. 94%, P < 0.01 for both, standard error 0.2).


CONCLUSIONS
PAA requiring intervention in women is a rare clinical occurrence. Although our series is limited, women requiring PAA repair had higher long-term mortality compared with men with a similar pathology and treatment strategy.
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Syed
S
Peeran
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN. Electronic address: DeMartino.Randall@Mayo.edu.
Randall R
RR
DeMartino
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Ying
Y
Huang
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Mark
M
Fleming
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Maju
M
Kalra
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Gustavo S
GS
Oderich
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Audra A
AA
Duncan
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Thomas C
TC
Bower
Division of Vascular and Endovascular Surgery, Mayo Clinic, Rochester, MN.
Peter
P
Gloviczki
D000368:Aged; D000369:Aged, 80 and over; D000671:Amputation, Surgical; D000783:Aneurysm / Q000000981:diagnostic imaging / Q000401:mortality / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation; D018572:Disease-Free Survival; D057510:Endovascular Procedures; D005260:Female; D054624:Health Status Disparities; D006801:Humans; D053208:Kaplan-Meier Estimate; D015993:Life Tables; D008026:Ligation; D023821:Limb Salvage; D008297:Male; D008875:Middle Aged; D008910:Minnesota; D011150:Popliteal Artery / Q000000981:diagnostic imaging / Q000601:surgery*; D012042:Registries; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D012501:Saphenous Vein / Q000637:transplantation; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures / Q000009:adverse effects / Q000401:mortality