Formation of [Ru(III)(edta)(SNO)](2-) in Ru(III)(edta)-Mediated S-Nitrosylation of Bisulfide Ion.
The reaction of hydrogen sulfide (H2S) and nitric oxide (NO) is of great physiological significance in human organisms. Our present studies show that Ru(III)(edta) (edta(4-) = ethylenediaminetetraacetate) mediates the S-nitrosylation of bisulfide ion (HS(-)) using NO to form [Ru(III)(edta)(SNO)](2-), the first-ever example of a ruthenium complex containing thionitrite (SNO(-)) in aqueous solution. The reaction product [Ru(III)(edta)(SNO)](2-) was characterized by IR, electron paramagnetic resonance, and electrospray ionization mass spectroscopy. Our studies further show that formation of the putative thionitrous acid coordinated to Ru(III)(edta) does not occur via the reaction of [Ru(III)(edta)NO](-) with HS(-).
Chemistry and Biomimetics Group, CSIR-Central Mechanical Engineering Research Institute , M.G. Avenue, Durgapur 713209, India.
Debabrata
D
Chatterjee
Chemistry and Biomimetics Group, CSIR-Central Mechanical Engineering Research Institute , M.G. Avenue, Durgapur 713209, India.
Papiya
P
Sarkar
Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.
Maria
M
Oszajca
Faculty of Chemistry, Jagiellonian University , Ingardena 3, 30-060 Krakow, Poland.|Department of Chemistry and Pharmacy, University of Erlangen-Nuremberg , Egerlandstr. 1, 91058 Erlangen, Germany.
Rudi
R
van Eldik