Infections caused by Tissierella praeacuta: A report of two cases and literature review.
Herein we report two cases of infections caused by Tissierella praeacuta and a review of the literature. The first case was a septic pseudarthrosis of the left femur after multiple fractures. Two per-operative samples were positive with T. praeacuta. The patient was successfully treated by piperacillin - tazobactam and metronidazole. The second case was a bacteremia in a patient suffering from pyonephrosis and a hepatic abscess. The treatment was meropenem. No relapses were observed in both cases. Identification of the strains using MALDI-TOF coupled to mass spectrometry (MS) (Beckman coulter, France) was inconclusive in the two cases. Identification by 16S rRNA sequencing was then performed. This bacterium was susceptible to beta-lactams, chloramphenicol, rifampicine and metronidazole.
Laboratoire de microbiologie clinique, GH Paris Saint-Joseph, Paris, France.
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Caméléna
Equipe mobile de microbiologie clinique, GH Paris Saint-Joseph, Paris, France.
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Pilmis
Equipe mobile de microbiologie clinique, GH Paris Saint-Joseph, Paris, France.
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Mollo
Service de chirurgie orthopédique, GH Paris Saint-Joseph, Paris, France.
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Hadj
Laboratoire de microbiologie clinique, GH Paris Saint-Joseph, Paris, France.
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Le Monnier
Laboratoire de microbiologie clinique, GH Paris Saint-Joseph, Paris, France. Electronic address: amizrahi@hpsj.fr.
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Mizrahi
D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D016470:Bacteremia / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D015373:Bacterial Typing Techniques; D005265:Femoral Neck Fractures / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005269:Femur / Q000382:microbiology / Q000473:pathology; D000068536:Bacillota / Q000235:genetics / Q000302:isolation & purification*; D006801:Humans; D008100:Liver Abscess / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D000077731:Meropenem; D010397:Penicillanic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D010878:Piperacillin / Q000627:therapeutic use; D000077725:Piperacillin, Tazobactam Drug Combination; D016133:Polymerase Chain Reaction; D011542:Pseudarthrosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D053018:Pyonephrosis / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D012336:RNA, Ribosomal, 16S / Q000235:genetics; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; D013845:Thienamycins / Q000627:therapeutic use; D016896:Treatment Outcome
D000900:Anti-Bacterial Agents; D012336:RNA, Ribosomal, 16S; D013845:Thienamycins; D000077725:Piperacillin, Tazobactam Drug Combination; D010397:Penicillanic Acid; D000077731:Meropenem; D010878:Piperacillin
16S rRNA; Blood stream infection; Joint infection; MALDI-TOF mass spectrometry; Tissierella praeacuta