Neurotrophic and Neuroprotective Effects of Muscle Contraction.
Physical activity has been shown to be associated with reduced risk of coronary heart disease but the same effect seems to be produced in neurological diseases.



In this review, we focused on the interplay between physical activity and some neurological conditions (Stroke, dementia, epilepsy, headache, Parkinson' s disease, amyotrophic lateral sclerosis, multiple sclerosis, insomnia, depression and anxiety) with the aim of describing the potential role of physical activity in the prevention of such diseases and the physiological mechanisms involved in these processes.



Despite a growing body of evidence which reveals that physical activity is able to reduce the frequency of neurological diseases, directly or indirectly by enhancing cardiovascular conditions, further studies are necessary to better characterize which type of exercise is useful for each condition.



Physical activity could represent an additional approach to fight against such diseases.
Valentina Arnao U. O di Neurologia e Neurofisiopatologia, Università degli Studi di Palermo, Via G. La Loggia n 1, 90129 - Italy. arnao.valentina@gmail.com.
Valentina
V
Arnao
Domenico
D
Di Raimondo
Antonino
A
Tuttolomondo
Antonio
A
Pinto
D019208:Brain-Derived Neurotrophic Factor / Q000378:metabolism; D002560:Cerebrovascular Circulation; D003704:Dementia / Q000503:physiopathology; D063388:Endocannabinoids / Q000378:metabolism; D015444:Exercise; D006801:Humans; D008019:Life Style; D009119:Muscle Contraction; D009422:Nervous System Diseases / Q000503:physiopathology; D009424:Nervous System Physiological Phenomena; D018384:Oxidative Stress; D020521:Stroke / Q000503:physiopathology
D019208:Brain-Derived Neurotrophic Factor; D063388:Endocannabinoids