[Acute toxicity of LDS, a molluscicide, to non-target organisms].
OBJECTIVE
To evaluate the acute toxicity of 10% LDS, a new molluscicide, to non-target organisms.


METHODS
Based on "Chemical pesticide environmental safety test evaluation standard", an acute toxicity test was carried out with Coturnix coturnix japonica (quail), Apis mellifera L (bee), Bombyx mori (silkworm), and Brachydonio rerio (zebra fish) , and the skin stimulus test was also performed with guinea pig.


RESULTS
The quails had no toxic symptoms while the maximum poisoning concentration of LDS was 200 mg/kg (no toxicity). LC₅₀ of bees was 2.68 x 10³ mg/L (low toxicity). After 96 hours, no silkworms died in each group of different concentrations of LDS while the most concentration was 6.00 x 10² mg/kg, but there were some toxic symptoms such as inappetence and inactive in the high concentration group as compared to the blank control group (low toxic). LC₅₀ (96 h) of zebra fish was 6.16 mg/L (medium toxicity).


CONCLUSIONS
LDS has no toxicity to Coturnix coturnix japonica, low toxicity to Apis mellifera L and Bombyx mori, and medium toxicity to Brachydonio rerio. Compared with niclosamide ethanolamine salt, the toxicity to the fish is lower, and therefore, it is more suitable for the field application.
Yi
Y
Yuan
Min
M
Liu
Ru-juan
RJ
Chen
Feng-hua
FH
Wei
Gui-lin
GL
Li
Jian-qiang
JQ
Li
Xing-jian
XJ
Xu
D000818:Animals; D001516:Bees / Q000187:drug effects / Q000254:growth & development; D001681:Biological Assay; D012831:Bombyx / Q000187:drug effects / Q000254:growth & development; D003370:Coturnix / Q000254:growth & development; D004305:Dose-Response Relationship, Drug; D006168:Guinea Pigs / Q000254:growth & development; D007928:Lethal Dose 50; D008975:Molluscacides / Q000633:toxicity*; D018675:Toxicity Tests; D015027:Zebrafish / Q000254:growth & development
D008975:Molluscacides