Acute Dystonia Following a Switch in Treatment from Atomoxetine to Low-dose Aripiprazole.
The present report describes the cases of a 17-year-old male patient and a 13-year-old female patient who developed acute dystonia following the administration of low-dose aripiprazole (5 mg/day) after the cessation of atomoxetine treatment. Although aripiprazole-induced dystonia has been previously reported in the literature, it is rare, and most of these cases were associated with doses higher than 5 mg/day. Furthermore, both of the patients in the present study discontinued atomoxetine prior to the initiation of aripiprazole treatment; thus, this report also discussed the possible mechanisms underlying the manifestation of dystonia from the perspective of neurotransmitter activity.
Department of Child and Adolescent Psychiatry, School of Medicine, Pamukkale University, Denizli.
Ömer
Ö
Başay
Department of Child and Adolescent Psychiatry, School of Medicine, Pamukkale University, Denizli.
Burge Kabukcu
BK
Basay
Department of Child and Adolescent Psychiatry, School of Medicine, Pamukkale University, Denizli.
Önder
Ö
Öztürk
Department of Child and Adolescent Psychiatry, School of Medicine, Ege University, Izmir, Turkey.
Zeki
Z
Yüncü
Aripiprazole; Atomoxetine; Dystonia