Living donor liver transplantation in the USA.
Living donor liver transplant (LDLT) accounts for a small volume of the transplants in the USA. Due to the current liver allocation system based on the model for end-stage liver disease (MELD), LDLT has a unique role in providing life-saving transplantation for patients with low MELD scores and significant complications from portal hypertension, as well as select patients with hepatocellular carcinoma (HCC). Donor safety is paramount and has been a topic of much discussion in the transplant community as well as the general media. The donor risk appears to be low overall, with a favorable long-term quality of life. The latest trend has been a gradual shift from right-lobe grafts to left-lobe grafts to reduce donor risk, provided that the left lobe can provide adequate liver volume for the recipient.
Simmons Transplant Institute, Baylor University Medical Center, Dallas, Texas, USA.
Peter T W
PT
Kim
Simmons Transplant Institute, Baylor University Medical Center, Dallas, Texas, USA.
Giuliano
G
Testa
Donor risk; left-lobe graft; liver transplantation; living donor; mortality