Impact of postoperative drainage autologous blood re-transfusion on the coagulation parameters and D-dimer levels of patients after total hip arthroplasty.
BACKGROUND
Postoperative drainage autologous blood re-transfusion (ABT) is an important treatment method that maintains a high haemoglobin (HGB) content and obviates the need for allogeneic blood transfusion in patients after surgery. However, the safety of ABT remains controversial.


OBJECTIVE
This study aimed to investigate the safety of postoperative drainage ABT in primary total hip arthroplasty (THA). In this randomized, controlled study, patients undergoing THA were selected and randomly divided into two groups. A device for postoperative ABT was used for the 49 patients in the ABT group, whereas conventional postoperative vacuum drainage was used for the 42 patients in the drainage blood (Drain) group without ABT. The coagulation parameters and D-dimer (DD) levels of the two groups of patients were recorded before surgery (T0) and on postoperative days one (T1), three (T2), seven (T3), and 14 (T4).


RESULTS
A within-group comparison after THA showed that the postoperative fibrinogen (FIB) and DD levels were higher than those before surgery in both groups (P < 0.01). A between-group comparison showed that, at different time points, the postoperative drainage blood amount and the coagulation parameters were not significantly different between the two groups. Compared with the Drain group, the DD levels in the ABT group were significantly higher at T1, T2, and T3 (P < 0.05).


CONCLUSIONS
Postoperative drainage ABT did not significantly impact the coagulation parameters of patients after THA. However, the DD levels after ABT significantly increased, which may affect the risk of thrombosis.
Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China; Department of Joint Surgery, Panyu Central Hospital, Guangzhou 511400, China.
Cheng
C
Luo
Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
Xiangping
X
Luo
Department of Anesthesiology, Panyu Central Hospital, Guangzhou 511400, China.
Yingyi
Y
He
Department of Joint Surgery, Panyu Central Hospital, Guangzhou 511400, China.
Jiewen
J
Li
Department of Joint Surgery, Panyu Central Hospital, Guangzhou 511400, China.
Bingsheng
B
Huang
Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China.
Lijun
L
Lin
Department of Orthopedics, Zhujiang Hospital, Southern Medical University, Guangzhou 510282, Guangdong Province, China. Electronic address: qili565@foxmail.com.
Qi
Q
Li
D000368:Aged; D019644:Arthroplasty, Replacement, Hip; D001777:Blood Coagulation; D001804:Blood Transfusion, Autologous; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000378:metabolism*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care
D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D
Coagulation parameters; D-dimer; Drainage autologous blood re-transfusion; Total hip arthroplasty