Cutaneous Small/Medium CD4+ Pleomorphic T-Cell Lymphoma-Like Nodule in a Patient With Erythema Chronicum Migrans.
CD4+ small/medium pleomorphic T-cell lymphoma is a relatively rare subtype of cutaneous lymphoproliferative disorder with an indolent clinical behavior. The place of this condition among lymphomas is debatable. The authors describe a rare case of the direct association of CD4 small/medium pleomorphic T-cell lymphoma-like solitary nodule with Borrelia burgdorferi infection in a 5-year-old boy, discuss the reactive nature of this condition, and emphasize the importance of clinicopathological correlation.
*Department of Dermatology, University of Pittsburgh, Pittsburgh, PA; †Division of Hematopathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA; ‡Division of Molecular and Genomic Pathology, Department of Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA; and §Pediatric Dermatology, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA.
Nil
N
Celebi Cherukuri
Christine G
CG
Roth
Nidhi
N
Aggarwal
Jonhan
J
Ho
Robin
R
Gehris
Oleg E
OE
Akilov
D015496:CD4-Positive T-Lymphocytes / Q000276:immunology*; D002675:Child, Preschool; D003937:Diagnosis, Differential; D015787:Erythema Chronicum Migrans / Q000276:immunology* / Q000473:pathology*; D006801:Humans; D016410:Lymphoma, T-Cell, Cutaneous / Q000276:immunology / Q000473:pathology*; D008297:Male; D012878:Skin Neoplasms / Q000276:immunology / Q000473:pathology*