Timing of Coronary Bypass Surgery in Patients Receiving Clopidogrel: The Role of VerifyNow.
We briefly report for the first time the association between a point of care platelet recovery test and the timing of coronary artery bypass grafting after clopidogrel withdrawal. We observe an association between suggested wait days and platelet recovery unit values that might potentially allow for safe shorter wait times before coronary artery bypass grafting without increased bleeding. Our results represent an observation and should prompt further validation.
Brigham and Women's Hospital, Boston, Massachusetts, USA.
Kareem
K
Bedeir
Sinai Hospital, Center for Thrombosis Research, Baltimore, Maryland, USA.
Kevin
K
Bliden
Sinai Hospital, Center for Thrombosis Research, Baltimore, Maryland, USA.
Udaya
U
Tantry
Sinai Hospital, Center for Thrombosis Research, Baltimore, Maryland, USA. Electronic address: purbel@lifebridgehealth.org.
Paul A
PA
Gurbel
Medizinische Universitat Graz, Graz, Austria.
Elisabeth
E
Mahla
D000077144:Clopidogrel; D001026:Coronary Artery Bypass / Q000379:methods; D017408:Guidelines as Topic; D006801:Humans; D010975:Platelet Aggregation Inhibitors / Q000008:administration & dosage*; D019095:Point-of-Care Systems; D019106:Postoperative Hemorrhage / Q000517:prevention & control; D011300:Preoperative Care / Q000379:methods; D012307:Risk Factors; D013988:Ticlopidine / Q000008:administration & dosage / Q000031:analogs & derivatives*; D016896:Treatment Outcome
D010975:Platelet Aggregation Inhibitors; D000077144:Clopidogrel; D013988:Ticlopidine