Solid Organ Transplantation in HIV+ Recipients: Italian Experience.
BACKGROUND
According to current estimates, there are about 540,000 patients who are infected with HIV in Western Europe, of which about 3100 are potential candidates for organ transplantation. In Italy, there are currently 85 HIV patients on the transplant list.


METHODS
Organ transplantation activity in HIV recipients from 2002 to December 2014 was assessed from the database provided by the Transplant Center of Modena until the year 2011. For the years 2012 to 2014, data are from the Transplant Information System (SIT). The follow-up data have been extracted from the function "Quality" of the SIT.


RESULTS
The transplant centers on Italian territory that meet the requirements according to national protocol are in total 29: 11 for the liver, 9 for the kidney including 1 pediatric, 3 for the heart, 3 for the lungs, and for 3 for the combined kidney-pancreas. Since 2002, 257 organ transplantations were carried out, including 185 liver, 59 kidney, 5 combined liver-kidney, 5 combined kidney-pancreas, 2 heart, and 1 double lung. The first cause of death is represented by co-hepatitis C virus infection, in particular in 26 liver recipients (37%) and in 3 kidney recipients (20%).


CONCLUSIONS
The analysis showed that transplantation activity in HIV is on the rise, especially in the last 2 years, with an outcome similar to that reported in the literature.
Italian National Transplant Center, Rome, Italy. Electronic address: vemorabito@gmail.com.
V
V
Morabito
Insubria University, Varese, Italy.
P
P
Grossi
Italian National Transplant Center, Rome, Italy.
L
L
Lombardini
Italian National Transplant Center, Rome, Italy.
A
A
Ricci
Italian National Transplant Center, Rome, Italy.
S
S
Trapani
Italian National Transplant Center, Rome, Italy.
D
D
Peritore
Italian National Transplant Center, Rome, Italy.
A
A
Gaeta
Italian National Transplant Center, Rome, Italy.
D
D
Ballanti
Italian National Transplant Center, Rome, Italy.
E
E
Del Sordo
Italian National Transplant Center, Rome, Italy.
L
L
Rizzato
Italian National Transplant Center, Rome, Italy.
A
A
Nanni Costa
D060085:Coinfection; D058625:End Stage Liver Disease / Q000150:complications* / Q000601:surgery; D005060:Europe; D015658:HIV Infections / Q000150:complications*; D006333:Heart Failure / Q000150:complications / Q000601:surgery*; D016027:Heart Transplantation; D006526:Hepatitis C / Q000150:complications*; D006801:Humans; D007558:Italy; D007676:Kidney Failure, Chronic / Q000150:complications* / Q000601:surgery; D016030:Kidney Transplantation; D016031:Liver Transplantation; D008171:Lung Diseases / Q000150:complications / Q000601:surgery*; D016040:Lung Transplantation; D016035:Pancreas Transplantation; D016896:Treatment Outcome