Sleeve Gastrectomy and Type 2 Diabetes Mellitus: a Systematic Review of Long-Term Outcomes.
Long-term T2DM resolution rates are not well established following the laparoscopic sleeve gastrectomy (LSG). The aim of this paper was to systematically review the evidence on the efficacy of the LSG on long-term T2DM resolution. A comprehensive electronic literature search was conducted. Included studies reported 5-year follow-up of T2DM outcomes following the LSG. Eleven studies (n = 1354) were included in the systematic review. T2DM patients (n = 402) encompassed 29.7 % of patients. Diabetes prevalence decreased post-operatively to 20.5 % at 5 years, with diabetes resolution occurring in 60.8 % of patients. Mean plasma glucose levels and haemoglobin A1c values fell from 170.3 to 112.0 mg/dL and 8.3 to 6.7 % respectively at the 5-year mark. The LSG is an effective long-term metabolic surgery for patients with T2DM.
Department of Surgery, 2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 840-112 Street, Edmonton, Alberta, T6G 2B7, Canada. nswitzer@ualberta.ca.
Noah J
NJ
Switzer
Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Shalvin
S
Prasad
Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Estifanos
E
Debru
Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Neal
N
Church
Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Philip
P
Mitchell
Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
Richdeep S
RS
Gill
D001786:Blood Glucose / Q000032:analysis*; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000601:surgery*; D005743:Gastrectomy; D006442:Glycated Hemoglobin / Q000032:analysis*; D006801:Humans; D009767:Obesity, Morbid / Q000097:blood / Q000601:surgery*; D016896:Treatment Outcome
D001786:Blood Glucose; D006442:Glycated Hemoglobin
Diabetes; Laparoscopic; Long-term results; Sleeve gastrectomy