Management of Pain in Complex Nerve Injuries.
Traumatic nerve injuries can be devastating and life-changing events, leading to functional morbidity and psychological stress and social constraints. Even in the event of a successful surgical repair with recovered motor function, pain can result in continued disability and poor quality of life. Pain after nerve injury can also prevent recovery and return to preinjury life. It is difficult to predict which patients will develop persistent pain; once incurred, pain can be even challenging to manage. This review seeks to define the types of pain following peripheral nerve injuries, investigate the pathophysiology and causative factors, and evaluate potential treatment options.
Department of Surgery, Palo Alto VA, Suite 400, 770 Welch Road, Palo Alto, CA 94304, USA.
Gabrielle
G
Davis
Department of Surgery, Palo Alto VA, Suite 400, 770 Welch Road, Palo Alto, CA 94304, USA; Division of Plastic Surgery, Stanford University, Suite 400, 770 Welch Road, Palo Alto, CA 94304, USA. Electronic address: curtincatherine@yahoo.com.
Catherine M
CM
Curtin
D001917:Brachial Plexus / Q000293:injuries*; D020516:Brachial Plexus Neuropathies / Q000150:complications / Q000503:physiopathology; D020918:Complex Regional Pain Syndromes / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D009437:Neuralgia / Q000209:etiology / Q000503:physiopathology / Q000628:therapy*; D009463:Neuroma / Q000209:etiology / Q000628:therapy; D059348:Peripheral Nerve Injuries / Q000150:complications* / Q000503:physiopathology; D011788:Quality of Life
CRPS; Nerve injuries; Neuroma; Neuropathic pain; Pain