Critical analysis of anatomical landmarks within the sphenoid sinus for transsphenoidal surgery.
The transsphenoidal approach to the sellar region has been introduced more than a 100 years ago. It is the accepted standard operative corridor to pathologies of the pituitary gland and surrounding structures. There are anatomical landmarks within the sphenoid sinus that are used for orientation directing to the sella floor or the cavernous sinus. Yet, little data can be found on the consistency of these landmarks. It is the aim of this study to evaluate the reliability of these anatomical landmarks for the surgeon's orientation. A total of 245 computed tomography (CT) volume data sets of the cranium performed according to a standardized protocol were analyzed for study purposes. CT scans of the cranium of 125 patients admitted to the emergency room of our hospital receiving a trauma spiral according to the local protocol were employed as a control group when no pathology in the sellar region was observed. In addition, preoperative CT scans of a group of 120 patients diagnosed with pituitary adenomas between 2009 and 2013 were analyzed. Image analysis of the anatomical landmarks included the minimal intercarotid distance (ICD), diameter of the sphenoid sinus (DSS), direction of the septum sinuum sphenoidalium (SSS), and the distance between vomer and clivus (VCD). The overall mean ICD was 16.2 mm, with patients suffering from adenomas showing a mean ICD of 15.8 mm compared with an average 16.5 mm in the control group. DSS was equal for both groups (adenoma group: mean 31.5 mm; controls: mean 31.3 mm). Mean VCD was 27.9 mm in patients with pituitary adenomas compared with 26.7 mm in controls. A septum of the sphenoid sinus located in the midline was found in overall 23 % only. SSS was directed into the bony shield of the internal carotid artery in 28 % of underlying tumors and in 37 % of the control group. This is the first detailed description of landmarks of the sphenoid sinus based on a large radiologic-anatomical analysis of CT scans yielding a wide variation and high inconsistency of these landmarks. From out data, we suggest that the surgeon approaching the sphenoid sinus should handle the anatomical landmarks with care bearing their inconsistency in mind. A thorough planning of the procedure up front is highly recommended. Usage of a navigation system considering the bony structures might as well facilitate as steady the approach to the sellar region in some cases for the patient's sake.
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany. yahya.ahmadipour@uk-essen.de.
Yahya
Y
Ahmadipour
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Elias
E
Lemonas
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Homajoun
H
Maslehaty
Institute of Radiology, University Hospital Essen, Essen, Germany.
Sophia
S
Goericke
Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Essen, Essen, Germany.
Boris A
BA
Stuck
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Nicolai
N
El Hindy
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany.
Ulrich
U
Sure
Department of Neurosurgery, University Hospital Essen, Hufelandstrasse 55, 45122, Essen, Germany. oliver.mueller@uk-essen.de.
Oliver
O
Mueller
D000236:Adenoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000328:Adult; D059925:Anatomic Landmarks / Q000000981:diagnostic imaging*; D002343:Carotid Artery, Internal / Q000000981:diagnostic imaging; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D010911:Pituitary Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D015203:Reproducibility of Results; D019291:Skull Base / Q000000981:diagnostic imaging; D013100:Sphenoid Bone / Q000000981:diagnostic imaging; D013101:Sphenoid Sinus / Q000000981:diagnostic imaging* / Q000601:surgery; D014057:Tomography, X-Ray Computed
Anatomical landmarks; Pituitary adenomas; Sphenoid sinus; Transsphenoidal approach