Wormhole Travel for Macrophages.
Leukocyte recruitment is generally achieved by rapid migration of inflammatory cells out of circulation, through modified blood vessels, and into affected tissues. Now, Wang and Kubes show that macrophages can be rapidly recruited from body cavities to the liver, via a non-vascular route, where they help to coordinate tissue repair.
Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, USA.
Yasutaka
Y
Okabe
Department of Immunobiology, Howard Hughes Medical Institute, Yale University School of Medicine, 300 Cedar Street, New Haven, CT 06520, USA. Electronic address: ruslan.medzhitov@yale.edu.
Ruslan
R
Medzhitov
D006801:Humans; D007962:Leukocytes; D008099:Liver / Q000098:blood supply; D008264:Macrophages