[Metabolic and cardiovascular consequences of suction-assisted lipectomy: Systematic review].
BACKGROUND
Suction-assisted lipectomy is one of the most frequent procedures in plastic surgery. The aim of this study was to investigate whether suction-assisted lipectomy causes changes in the carbohydrates and lipid metabolism and the potential effects on cardiovascular risk factors.


METHODS
We interrogated five databases: Medline, American College of Physicians Journal Club Database, Cochrane central register of controlled trials, Cochrane database of systematic reviews, Database of abstracts of reviews of effects. A systematic review of the literature was performed in order to compare results of randomized controlled trials and observational studies concerning changes in weight, metabolism, endocrinology, inflammatory markers and cardiovascular risk factors after suction-assisted lipectomy. All articles were assessed by criteria from Oxford Center For Evidence Based Medicine (OCEBM).


RESULTS
The search resulted in 40 articles: 12 experimental animal studies and 28 human studies.


CONCLUSIONS
Different metabolic parameters are affected by suction-assited lipectomy. First, all articles point out a decrease of body weight after suction-assisted lipectomy. Weight lost only affects fat mass without any change of lean mass. The potential compensatory growth of visceral fat seems to be counteracted by physical activity. Then, resting energy expenditure seems to be stable or decrease after the surgery. This reduction is significantly related to the decrease of leptin levels and also seems to be counteracted by physical activity. About adipocytokines, leptin level decreases after suction-assisted lipectomy while results are contradictory about adiponectin and resistin levels. However adiponectin seems to tend to increase after surgery. Inflammatory markers seem to increase within first hours after surgery. Then they seem to decrease or remain at the preoperative levels. Fasting insulin level decreases and is linked to the aspirated volume. So insulin sensitivity seems to be improved. Concerning lipid profil, it tends to remain the same or to be improved by suction-assisted lipectomy. In conclusion, regarding all the literature, there is still debate about metabolic effect of suction-assisted lipectomy. Prospective clinical studies are needed to confirm or invalidate some hypotheses. These studies must consider some potential biases as physical activity, diet and medical treatment modifications (statins).
Domaine universitaire du Sart-Tilman, CHU de Liège, B. 35, 4000 Liège, Belgique. Electronic address: fxcrahay@hotmail.com.
F-X
FX
Crahay
Service de chirurgie plastique et maxillo-faciale, domaine universitaire du Sart-Tilman, CHU de Liège, B. 35, 4000 Liège, Belgique.
J L
JL
Nizet
D054392:Adipokines / Q000097:blood; D000818:Animals; D002784:Cholesterol / Q000097:blood; D004734:Energy Metabolism; D006801:Humans; D007328:Insulin / Q000097:blood; D020738:Leptin / Q000378:metabolism; D015187:Lipectomy / Q000009:adverse effects*; D008055:Lipids / Q000097:blood; D013396:Suction; D015431:Weight Loss
D054392:Adipokines; D007328:Insulin; D020738:Leptin; D008055:Lipids; D002784:Cholesterol
Adipocytokines; Cardiovascular; Consequences; Conséquences; Cytokines; Facteur de risque cardiovasculaire; Lipoaspiration; Metabolic; Métabolique; Suction-assisted lipectomy