[Surgical management of primary hyperthyroidism and coexistent thyroid carcinoma].
OBJECTIVE
To evaluated the results of surgical treatment for primary hyperparathyroidism coexistent with thyroid cancer.


METHODS
From March 2007 to May 2014, 27 patients suffered thyroid carcinoma coexistent with primary hyperparathyroidism with pathological and laboratory confirmation were studied retrospectively. In 8 of 27 cases thyroidectomy and parathyroidectomy were performed separately, with interval time of 3 to 26 months, and in the remaining cases both procedures were done simultaneously. During surgery quick PTH evaluation and calcium measure were routinely performed.


RESULTS
Postoperative temporary hypoparathyroidism was found in 26 of 27 cases, and postoperative permanent hypoparathyroidism developed in 4 cases that underwent separate operation. Limited movement of vocal cord was showed in 4 cases after parathyroidectomy, but it lasted no more than 2 months. No permanent paralysis of recurrent laryngeal nerve was found. No thyroid cancer or hyperparathyroidism was found with follows-up of 11 to 43 months.


CONCLUSIONS
Thyroidectomy and parathyroidectomy performed separately have higher risk to develop hypoparathyroidism than they are done simultaneously. PTH and calcium should be evaluated in patients with thyroid carcinoma whenever available.
Department of Otorhinolaryngology Head and Neck Surgery, Shijitan Hospital, Capital Medicial University, College of Otorhinolaryngology, Captial Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery (Capital Medicial University), Ministry of Education, Beijing 100038, China.
H
H
Shen
Department of Otorhinolaryngology Head and Neck Surgery, Shijitan Hospital, Capital Medicial University, College of Otorhinolaryngology, Captial Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery (Capital Medicial University), Ministry of Education, Beijing 100038, China.
B B
BB
Wei
Department of Otorhinolaryngology Head and Neck Surgery, Shijitan Hospital, Capital Medicial University, College of Otorhinolaryngology, Captial Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery (Capital Medicial University), Ministry of Education, Beijing 100038, China.
H
H
Xie
Department of Otorhinolaryngology Head and Neck Surgery, Shijitan Hospital, Capital Medicial University, College of Otorhinolaryngology, Captial Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery (Capital Medicial University), Ministry of Education, Beijing 100038, China.
Z X
ZX
Peng
Department of Otorhinolaryngology Head and Neck Surgery, Shijitan Hospital, Capital Medicial University, College of Otorhinolaryngology, Captial Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery (Capital Medicial University), Ministry of Education, Beijing 100038, China.
J
J
Wang
Department of Otorhinolaryngology Head and Neck Surgery, Shijitan Hospital, Capital Medicial University, College of Otorhinolaryngology, Captial Medical University, Key Laboratory of Otorhinolaryngology Head and Neck Surgery (Capital Medicial University), Ministry of Education, Beijing 100038, China.
J
J
Bai
D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications / Q000601:surgery*; D007011:Hypoparathyroidism / Q000175:diagnosis / Q000209:etiology; D016105:Parathyroidectomy / Q000009:adverse effects; D011183:Postoperative Complications / Q000175:diagnosis; D012009:Recurrent Laryngeal Nerve; D012189:Retrospective Studies; D013964:Thyroid Neoplasms / Q000150:complications / Q000601:surgery*; D013965:Thyroidectomy / Q000009:adverse effects; D016896:Treatment Outcome; D014826:Vocal Cord Paralysis