[Nasal endoscope negative pressure cleaning and sinupret drops to treat radiation nasosinusitis].
OBJECTIVE
To observe the effect of nasal endoscope negative pressure cleaning and sinupret drops to treat radiation nasosinusitis (RNS).


METHODS
One hundred and fifty-three patients with nasopharyngeal carcinoma were randomly divided into treatment group A, B, C . Group A using nasal endoscope negative pressure cleaning and sinupret drops, group B using nasal endoscope negative pressure cleaning and normal saline spray washing, group C using saline nasal irrigation through nasal catheter. All patients with sinusitis condition were evaluated at the end of radiotherapy, three months and six months after radiotherapy.


RESULTS
Comparison between groups, three periods of RNS incidence, moderate to severe RNS incidence are A < B < C. Six months after radiotherapy, group A compared with group C, there are significant difference (P < 0.01), group A and group C compared with group B respectively, the difference was statistically significant (P < 0.05).


CONCLUSIONS
Nasal endoscope negative pressure cleaning and sinupret drops can significantly reduce the long-term incidence of RNS, especially obviously reduce the incidence of moderate to severe RNS,which is a practical and effective method to treat RNS.
Wenbiao
W
Lin
Chaokun
C
Quan
Longcheng
L
Zhang
D002277:Carcinoma; D004724:Endoscopy; D006801:Humans; D015994:Incidence; D009296:Nasal Cavity; D055556:Nasal Lavage; D000077274:Nasopharyngeal Carcinoma; D009303:Nasopharyngeal Neoplasms / Q000532:radiotherapy*; D010936:Plant Extracts / Q000008:administration & dosage* / Q000627:therapeutic use; D011878:Radiotherapy / Q000009:adverse effects*; D012852:Sinusitis / Q000628:therapy*; D012965:Sodium Chloride
D010936:Plant Extracts; D012965:Sodium Chloride; C028353:Sinupret