[HCV infection and specific T lymphocyte immunity].
Adaptive immunity, especially the cellular immunity mediated by T lymphocytes, plays an important role in the body's fight against hepatitis C virus (HCV) infection. The clearance of HCV requires a strong, sustained, and multi-epitope response from specific T lymphocytes, and the dysfunction of specific T lymphocytes is the major reason for chronic infection. Effective treatment can restore the function of specific T lymphocytes to a certain extent. This article reviews the features and related mechanisms of immune response from specific T lymphocytes when the prognosis of patients with HCV infection is different.
Infectious Disease Diagnosis, Treatment and Research Center, 302 Military Hospital of China-Peking University Teaching Hospital, Beijing 100039, China.
J J
JJ
Shi
Infectious Disease Diagnosis, Treatment and Research Center, 302 Military Hospital, Beijing 100039, China.
J Y
JY
Zhang
Infectious Disease Diagnosis, Treatment and Research Center, 302 Military Hospital of China-Peking University Teaching Hospital, Beijing 100039, China.
X X
XX
Zhang
Infectious Disease Diagnosis, Treatment and Research Center, 302 Military Hospital, Beijing 100039, China; Infectious Disease Diagnosis, Treatment and Research Center, 302 Military Hospital of China-Peking University Teaching Hospital, Beijing 100039, China.
F S
FS
Wang
D016174:Hepacivirus / Q000276:immunology*; D006526:Hepatitis C / Q000276:immunology*; D019698:Hepatitis C, Chronic / Q000276:immunology*; D006801:Humans; D007111:Immunity, Cellular; D013601:T-Lymphocytes / Q000276:immunology / Q000821:virology*