Centromeres of a Different CAL-ibre.
Centromeres of higher eukaryotes are defined by the epigenetic inheritance of the centromere-specific CENP-A nucleosome. Reporting in Developmental Cell, Rosin and Mellone (2016) show that co-evolution of the CENP-A histone variant and its chaperone CAL1 accounts for species incompatibility between centromeric histones in Drosophila.
Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
Ewelina
E
Zasadzińska
Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: dfoltz@northwestern.edu.
Daniel R
DR
Foltz
D000818:Animals; D002503:Centromere; D004330:Drosophila; D029721:Drosophila Proteins; D006657:Histones; D009707:Nucleosomes
D029721:Drosophila Proteins; D006657:Histones; D009707:Nucleosomes