Reconstruction of human oncological tracheal defects with xenogenic acellular dermal matrix.
OBJECTIVE
This study aimed to explore the effectiveness of xenogenic acellular dermal matrix (xeno-ADM) in tracheal reconstruction.


METHODS
Two patients were treated with this surgical method to reconstruct the trachea in 2013. The patients were diagnosed with tracheal adenoid cystic carcinoma by histopathological biopsy. The tumor was resected with half of the tracheal circumference and repaired by xeno-ADM. The patients were followed up for 31 and 33 months, respectively.


RESULTS
No infection or tracheal fistula was observed. The grafts were clear. Both patients were successfully decannulated without dyspnea and could breathe and speak without prosthesis. The cervical mobility was not impaired.


CONCLUSIONS
Xeno-ADM was successfully used to reconstruct a stable and well-functioning trachea. This surgical method is simple, safe, and effective with fewer complications.
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Ping
P
Li
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Shisheng
S
Li
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Qinglai
Q
Tang
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Xiangbo
X
He
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Danhui
D
Yin
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China.
Shuang
S
Wang
Department of Otolaryngology, Head and Neck Surgery, the Second Xiangya Hospital, Central South University, Changsha 410011, Hunan, PR China. Electronic address: x16y2003@aliyun.com.
Xinming
X
Yang
D062088:Acellular Dermis; D000328:Adult; D003528:Carcinoma, Adenoid Cystic / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D006801:Humans; D008297:Male; D019651:Plastic Surgery Procedures / Q000379:methods*; D014057:Tomography, X-Ray Computed; D014132:Trachea / Q000601:surgery*; D014134:Tracheal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D014183:Transplantation, Heterologous
Reconstruction; Surgery; Tracheal carcinoma; Xenogeneic ADM