Comparison of Vertebral Artery and Middle Cerebral Artery Monitoring for Right-to-left Shunt Detection by Contrast-enhanced Transcranial Doppler.
Contrast-enhanced transcranial Doppler (c-TCD) is a reliable and reproducible method for right-to-left shunt (RLS) detection, with high sensitivity. Monitoring the middle cerebral artery (MCA) is an optimal choice, yet for patients with insufficient temporal bone windows or severe stenosis of carotid arteries, an alternative should be established. The aim of the present study was to further establish whether c-TCD with vertebral artery (VA) monitoring is as effective as MCA monitoring for RLS detection. We evaluated 194 subjects for RLS detection with VA and MCA monitoring simultaneously. There was no significant difference between the positive rates of VA and MCA monitoring for RLS detection. c-TCD with VA monitoring could be an alternative for RLS detection, with high sensitivity and specificity both at rest and during the Valsalva manoeuvre.
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Yu-Zhu
YZ
Guo
Department of Cardiac Surgery, The First Hospital of Jilin University, Changchun, China.
Yong-Sheng
YS
Gao
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Zhen-Ni
ZN
Guo
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Peng-Peng
PP
Niu
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Yi
Y
Yang
Neuroscience Center, Department of Neurology, The First Hospital of Jilin University, Changchun, China.
Ying-qi
YQ
Xing
D000328:Adult; D003287:Contrast Media; D005260:Female; D006801:Humans; D007089:Image Enhancement; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000502:physiology*; D012039:Regional Blood Flow; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods; D014711:Vertebral Artery / Q000502:physiology*
D003287:Contrast Media