Efficacy of ultrasound-guided core-needle biopsy in the diagnosis of hepatic alveolar echinococcosis: a retrospective analysis.
BACKGROUND
This study retrospectively analyzed the clinical data, laboratory results, imaging findings, and histopathological features of 28 patients who underwent ultrasound-guided core-needle biopsy from a hepatic lesion and were diagnosed with alveolar echinococcosis.


RESULTS
Among 28 patients included in the study, 16 were females and 12 were males. The mean age of the studied population was 53 ± 16 years, and the age range was 18-79 years. The most common presenting symptom was abdominal pain, which was observed in 14 patients. A total of 36 lesions were detected in the patients' livers, out of which 7 had a cystic appearance. Hepatic vascular involvement, bile duct involvement, and other organ involvement were depicted in 14, 5, and 7 patients, respectively. The average number of cores taken from the lesions was 2.7, ranging between 2 and 5. In histopathological evaluation, PAS+ parasitic membrane structures were visualized on a necrotic background in all cases. Regarding seven patients, who were operated, the pathological findings of preoperative percutaneous biopsies were in perfect agreement with the pathological examinations after surgical resections. None of the patients developed major complications after biopsy.


CONCLUSIONS
Ultrasound-guided core-needle biopsy is a minimally invasive, reliable, and effective diagnostic tool for the definitive diagnosis of hepatic alveolar echinococcosis.
Department of Radiology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Mesut
M
Bulakci
Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Mehmet
M
Ilhan
Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Suleyman
S
Bademler
Department of Radiology, Trakya University, Faculty of Medicine, Edirne, Turkey.
Erdem
E
Yilmaz
Department of Pathology, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Mine
M
Gulluoglu
Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Adem
A
Bayraktar
Department of Radiology, Medeniyet University, Faculty of Medicine, Istanbul, Turkey.
Murat
M
Asik
Department of General Surgery, Istanbul University, Istanbul Faculty of Medicine, Istanbul, Turkey.
Recep
R
Guloglu
D015746:Abdominal Pain / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001649:Bile Duct Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000473:pathology; D001707:Biopsy, Needle / Q000379:methods*; D004444:Echinococcosis, Hepatic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D048210:Echinococcus multilocularis / Q000302:isolation & purification; D019353:Endemic Diseases; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D014421:Turkey; D018084:Ultrasonography, Interventional; D055815:Young Adult