Widespread Dissemination of Carbapenem-Resistant Escherichia coli Sequence Type 167 Strains Harboring blaNDM-5 in Clinical Settings in China.
This study reports the increasing prevalence of clinical Escherichia coli of sequence type 167 (ST167) carrying both blaNDM-1 and blaNDM-5 on the conjugative IncX3 plasmid in various parts of China. Close surveillance is needed to monitor the future dissemination of ST167 strains that harbor blaNDM-5 or other blaNDM-like genes.
Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Yonglu
Y
Huang
Department of Transfusion, General Hospital of Shenyang Military Area Command, Shenyang, China.
Xiaonan
X
Yu
Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute, Shenzhen, People's Republic of China.
Miaomiao
M
Xie
Second Affiliated Hospital of Zhejiang University, Hangzhou, China.
Xuan
X
Wang
First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Kang
K
Liao
Department of Transfusion, General Hospital of Shenyang Military Area Command, Shenyang, China.
Wencheng
W
Xue
State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Edward Wai-Chi
EW
Chan
Second Affiliated Hospital of Zhejiang University, Hangzhou, China brigitte_zx@163.com sheng.chen@polyu.edu.hk.
Rong
R
Zhang
Shenzhen Key Laboratory for Food Biological Safety Control, Food Safety and Technology Research Center, Hong Kong PolyU Shen Zhen Research Institute, Shenzhen, People's Republic of China State Key Laboratory of Chirosciences, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong brigitte_zx@163.com sheng.chen@polyu.edu.hk.
Sheng
S
Chen
D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015780:Carbapenems / Q000494:pharmacology*; D002681:China; D004926:Escherichia coli / Q000187:drug effects* / Q000201:enzymology* / Q000235:genetics; D029968:Escherichia coli Proteins / Q000235:genetics / Q000378:metabolism; D008826:Microbial Sensitivity Tests; D001618:beta-Lactamases
D000900:Anti-Bacterial Agents; D015780:Carbapenems; D029968:Escherichia coli Proteins; D001618:beta-Lactamases