Fecal Transplantation using a Nasoenteric Tube during an Initial Episode of Severe Clostridium difficile Infection.
The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be a feasible treatment option for recurrent C. difficile infection; moreover, it may be an early treatment option for severe C. difficile infection. We report a case of severe C. difficile infection treated with fecal transplantation using a nasoenteric tube during an initial episode. This is the first reported case of fecal transplantation using a nasoenteric tube during an initial episode of C. difficile infection in Korea.
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Yong Duk
0000-0002-4588-4781
YD
Jeon
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Namki
N
Hong
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Jung Ho
JH
Kim
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Se Hee
SH
Park
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Sung Bae
SB
Kim
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
In Ji
IJ
Song
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Hea Won
HW
Ann
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Jin Young
JY
Ahn
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.
Sun Bean
SB
Kim
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Nam Su
NS
Ku
Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
Kyungwon
K
Lee
Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea.
Dongeun
D
Yong
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
June Myung
JM
Kim
Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea.; AIDS Research Institute, Yonsei University College of Medicine, Seoul, Korea.
Jun Yong
0000-0002-2775-3315
JY
Choi
Clostridium difficile; Fecal microbiota; Fecal transplantation; Nasoenteric tube