Acute effects of waterpipe smoking on blood pressure and heart rate: a real-life trial.
Waterpipe smoking is becoming a popular way of tobacco use in the world. Its acute effects on the cardiovascular system are not well investigated.



This is a trial designed to evaluate the acute effects of waterpipe smoking on blood pressure (BP) and heart rate (HR) in healthy adults. Individuals who ordered waterpipe in 6 Lebanese restaurants were enrolled (cases) and were compared to controls who consisted of subjects who were sitting at the same table of smokers but who did not smoke (passive smokers) and of subjects who were sitting in nonsmoking sections (nonsmokers). BP and HR were measured immediately before and 15 min after smoking or at baseline and 15 min later in controls.



A total of 194 subjects were enrolled: 101 waterpipe smokers, 51 passive smokers, and 42 nonsmokers. Systolic and diastolic BP and HR significantly increased after 15 min of smoking in cases (mean 3.1 mm Hg (95% CI 0.8-5.5; p = 0.009) for systolic BP, 2.1 mm Hg (95% CI 0-4.2; p = 0.053) for diastolic BP, and 6.3 beats/minute (95% CI 4.3-8.3; p < 0.001) for HR, but did not change in controls.



Waterpipe smoking for duration as short as 15 min has acute hemodynamic effects and significantly increases systolic BP and HR.
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Rabih R
RR
Azar
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Antonio H
AH
Frangieh
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Jad
J
Mroué
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Lilliane
L
Bassila
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Mohamad
M
Kasty
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Georges
G
Hage
a Division of Cardiology , Hotel Dieu de France Hospital and the St. Joseph University School of Medicine , Beirut , Lebanon.
Zena
Z
Kadri
D000328:Adult; D001794:Blood Pressure / Q000187:drug effects*; D005260:Female; D006339:Heart Rate / Q000187:drug effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D012907:Smoking / Q000503:physiopathology*; D000073867:Water Pipe Smoking / Q000009:adverse effects*; D055815:Young Adult
Blood pressure; heart rate; waterpipe smoking