Any route for melanoblasts to colonize the skin!
Melanocytes arise from the fourth embryonic layer, the neural crest. They emerge from the roof plate of the neural tube and migrate throughout the body. In mammals, these cells have the capacity to migrate in any type of environment and use various pathways and mechanisms to colonize the skin and hair, and for their maintenance throughout the life of the animal.
Institut Curie, INSERM U1021, Normal and Pathological Development of Melanocytes, PSL Research University, Orsay, France.|CNRS UMR 3347, University of Paris-Sud, University of Paris-Saclay, Orsay, France.|Equipe Labellisée Ligue Contre le Cancer, Orsay, France.
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Institut Curie, INSERM U1021, Normal and Pathological Development of Melanocytes, PSL Research University, Orsay, France.|CNRS UMR 3347, University of Paris-Sud, University of Paris-Saclay, Orsay, France.|Equipe Labellisée Ligue Contre le Cancer, Orsay, France.
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D000818:Animals; D002465:Cell Movement; D006801:Humans; D008544:Melanocytes; D012867:Skin / Q000196:embryology*
coat colour; development; fur; melanocyte; migration; neural crest; stem cell