Knowledge and Attitudes towards Antibiotic Use and Resistance - A Latent Class Analysis of a Swedish Population-Based Sample.
BACKGROUND
In 2006, a study investigating knowledge and attitudes regarding antibiotic use and resistance in Sweden, indicated high level of knowledge but also areas in need of improvement.


OBJECTIVE
(i) To provide an update on the knowledge and attitudes to antibiotic use and resistance of the Swedish population, and (ii) to identify which groups within the population are in particular need of improved knowledge or attitudes.


METHODS
A questionnaire was sent by post in 2013 to 2,500 randomly-selected individuals aged 18-74, living in Sweden. Latent class analyses were conducted to group respondents based on their responses. The association between socio-demographic characteristics and the probability of belonging to each latent class was assessed.


RESULTS
The response rate was 57%. Ninety-four per cent of the responders knew that bacteria could become resistant to antibiotics and the majority answered correctly to the questions regarding antibiotic resistance development. The respondents expressed confidence in doctors who decided not to prescribe antibiotics. Three latent classes related to 'knowledge regarding antibiotic use and resistance', two regarding 'attitudes towards antibiotic accessibility and infection prevention' and three regarding 'attitudes towards antibiotic use and effects' were revealed. Men, younger and more educated people were more knowledgeable but males had a less restrictive attitude. Respondents with high levels of knowledge on antibiotics were more likely to have appropriate restrictive attitudes to antibiotics.


CONCLUSIONS
Knowledge on antibiotic use and resistance is maintained high and has improved in Sweden compared to 2006. People with lower education and elderly are especially in need of improved knowledge about antibiotic use and resistance.
Karolinska Institutet, Department of Public Health Sciences, Tomtebodavägen 18A, Stockholm, Sweden.
Martina
M
Vallin
Karolinska Institutet, Department of Public Health Sciences, Tomtebodavägen 18A, Stockholm, Sweden.
Maria
M
Polyzoi
Karolinska Institutet, Department of Public Health Sciences, Tomtebodavägen 18A, Stockholm, Sweden.
Gaetano
G
Marrone
Karolinska Institutet, Department of Public Health Sciences, Tomtebodavägen 18A, Stockholm, Sweden.
Senia
S
Rosales-Klintz
Public Health Agency of Sweden, Nobels väg 18, Solna, Sweden.
Karin
K
Tegmark Wisell
Karolinska Institutet, Department of Public Health Sciences, Tomtebodavägen 18A, Stockholm, Sweden.
Cecilia
C
Stålsby Lundborg
D000293:Adolescent; D000328:Adult; D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001294:Attitude to Health; D001419:Bacteria / Q000187:drug effects*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000453:epidemiology*; D003430:Cross-Sectional Studies; D024881:Drug Resistance, Bacterial; D005260:Female; D005500:Follow-Up Studies; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D011795:Surveys and Questionnaires; D013548:Sweden / Q000453:epidemiology; D055815:Young Adult
D000900:Anti-Bacterial Agents