Copper-Promoted Double Oxidative C-H Amination Cascade for the Synthesis of Imidazo[1,5-a]quinolines.
A copper-promoted cascade reaction of 2-methylazaarenes and benzylamines has been developed via sequential double oxidative C(sp(3))-H aminations. This protocol provides straightforward access to imidazo[1,5-a]quinoline derivatives without employing prefunctionalized substrates.
School of Chemical Engineering, Anhui University of Science and Technology , Huainan, Anhui 232001, PR China.
Zhong
Z
Li
School of Chemical Engineering, Anhui University of Science and Technology , Huainan, Anhui 232001, PR China.
Song-Song
SS
Wu
School of Chemical Engineering, Anhui University of Science and Technology , Huainan, Anhui 232001, PR China.
Zai-Gang
ZG
Luo
School of Chemical Engineering, Anhui University of Science and Technology , Huainan, Anhui 232001, PR China.
Wei-Kang
WK
Liu
School of Chemical Engineering, Anhui University of Science and Technology , Huainan, Anhui 232001, PR China.
Cheng-Tao
CT
Feng
College of Food and Drug, Anhui Science and Technology University , Fengyang, Anhui 233100, PR China.
Shi-Tang
ST
Ma