How cells kill a "killer" messenger.
Establishing a link between the nonsense-mediated decay pathway and a gene associated with programmed cell death could explain why this pathway is essential in most, but not all, eukaryotes.
Institut Pasteur, Paris, France.|CNRS UMR3525, Paris, France.
Cosmin
C
Saveanu
Institut Pasteur, Paris, France.|CNRS UMR3525, Paris, France.
Alain
A
Jacquier
D006801:Humans; D059365:Nonsense Mediated mRNA Decay; D012333:RNA, Messenger / Q000235:genetics*
D012333:RNA, Messenger
D. melanogaster; Drosophila; Gadd45; NMD; Upf1; Upf2; cell biology; mRNA decay