Multicenter Cohort Study of Acute Myocardial Infarction in Korea　- Interim Analysis of the Korea Acute Myocardial Infarction Registry-National Institutes of Health Registry.
BACKGROUND
The Korea Acute Myocardial Infarction Registry (KAMIR)-National Institutes of Health (NIH) registry has the aim of evaluating the clinical characteristics, management, and long-term outcomes of patients with acute myocardial infarction (AMI) in Korea.


RESULTS
Patients hospitalized for AMI in 20 tertiary university hospitals in Korea have been enrolled since November 2011. The study is expected to complete the scheduled enrollment of approximately 13,000 patients in October 2015, and follow-up duration is up to 5 years for each patient. As of October 2015, an interim analysis of 13,623 subjects was performed to understand the baseline clinical profiles of the study population. The mean age was 64.1 years; 73.5% were male; and 48.2% were diagnosed with ST-segment elevation AMI. Hypertension is a leading cause of AMI in Korea (51.2%), followed by smoking (38.5%) and diabetes mellitus (28.6%). Percutaneous coronary intervention was performed in 87.4% and its success rate was very high (99.4%). In-hospital, 1-year, and 2-year mortality rates were 3.9%, 4.3%, and 8.6%, respectively. The rates of major adverse cardiac events at 1 and 2 years were 9.6% and 18.8%, respectively.


CONCLUSIONS
This analysis demonstrated the clinical characteristics of Korean AMI patients in comparison with those of other countries. It is necessary to develop guidelines for Asian populations to further improve their prognosis. (Circ J 2016; 80: 1427-1436).
Heart Center of Chonnam National University Hospital.
Ju Han
JH
Kim
Shung-Chull
SC
Chae
Dong Joo
DJ
Oh
Hyo-Soo
HS
Kim
Young Jo
YJ
Kim
Youngkeun
Y
Ahn
Myeong Chan
MC
Cho
Chong Jin
CJ
Kim
Jung-Han
JH
Yoon
Hyun-Young
HY
Park
Myung Ho
MH
Jeong
D002423:Cause of Death; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000453:epidemiology* / Q000401:mortality; D009316:National Institutes of Health (U.S.); D062645:Percutaneous Coronary Intervention / Q000401:mortality; D012042:Registries; D056910:Republic of Korea; D012307:Risk Factors; D014481:United States