Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive oxygen and nitrogen species.
Reactive oxygen (ROS) and nitrogen (RNS) species cause oxidative and nitrosative stresses, respectively. These stresses are implicated not only in diverse physiological processes but also in various pathological processes, including cancer and neurodegenerative disorders. In addition, some ROS and RNS in the environment are pollutants that threaten human health. As a consequence of these effects, sensitive methods, which can be employed to selectively monitor ROS and RNS in live cells, tissues and organisms as well as in environmental samples, are needed so that their biological roles can be understood and their concentrations in environmental samples can be determined. In this review, fluorescent, luminescent and colorimetric ROS and RNS probes, which have been developed since 2011, are comprehensively discussed.
Department of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea. jyoon@ewha.ac.kr.
Xiaoqiang
X
Chen
Fang
F
Wang
Ji Young
JY
Hyun
Tingwen
T
Wei
Jian
J
Qiang
Xintong
X
Ren
Injae
I
Shin
Juyoung
J
Yoon
D000818:Animals; D003124:Colorimetry; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D049449:Luminescence; D049408:Luminescent Agents / Q000737:chemistry*; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry; D009584:Nitrogen / Q000737:chemistry; D061848:Optical Imaging / Q000379:methods; D010100:Oxygen / Q000737:chemistry; D026361:Reactive Nitrogen Species / Q000032:analysis*; D017382:Reactive Oxygen Species / Q000032:analysis*
D005456:Fluorescent Dyes; D049408:Luminescent Agents; D026361:Reactive Nitrogen Species; D017382:Reactive Oxygen Species; D009584:Nitrogen; D010100:Oxygen