Novel cost-effective quality control approach for the Cepheid Xpert CT/NG assay for the detection of Chlamydia Trachomatis and Neisseria Gonorrhoeae.
The Xpert CT/NG is a rapid assay for detection of Neisseria gonorrhoeae and Chlamydia trachomatis. QC materials must be formulated to emulate human specimens, and are prohibitively expensive. A creative, cost-effective QC approach is proposed. The acceptable sample types for the Xpert CT/NG assay were extended to include eye swabs.
Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889. Electronic address: Maurice_Chan@cgh.com.sg.
Maurice
M
Chan
Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889.
Boran
B
Jiang
Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889.
Siew Yong Lily
SY
Ng
Department of Laboratory Medicine, Changi General Hospital, 2 Simei Street 3, Singapore 529889.
Thean Yen
TY
Tan
D001431:Bacteriological Techniques / Q000191:economics / Q000295:instrumentation / Q000379:methods / Q000592:standards*; D002584:Cervix Uteri / Q000382:microbiology; D002690:Chlamydia Infections / Q000175:diagnosis* / Q000382:microbiology / Q000652:urine; D002692:Chlamydia trachomatis / Q000235:genetics / Q000302:isolation & purification*; D019719:Diagnostic Equipment / Q000191:economics / Q000592:standards; D005123:Eye / Q000382:microbiology; D005260:Female; D006069:Gonorrhea / Q000175:diagnosis* / Q000382:microbiology / Q000652:urine; D006801:Humans; D025202:Molecular Diagnostic Techniques / Q000191:economics / Q000295:instrumentation / Q000379:methods / Q000592:standards*; D009344:Neisseria gonorrhoeae / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction / Q000191:economics / Q000295:instrumentation / Q000379:methods / Q000592:standards; D011786:Quality Control; D012680:Sensitivity and Specificity
AmpliTrol; CT/NG; Cepheid; Chlamydia trachomatis; Neisseria gonorrhoeae; Positive controls; Quality control; Xpert