Efficient Synthesis of 5-Carboxy-2'-Deoxypyrimidine Nucleoside 5'-Triphosphates.
An efficient P(V)-N activation method for the synthesis of 5-carboxy-2'-deoxyuridine and 5-carboxy-2'-deoxycytidine triphosphates directly from the corresponding phosphoropiperidate precursors has been developed.
a Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University , Nanchang , Jiangxi , PR China.
Shan-Shan
SS
Gong
a Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University , Nanchang , Jiangxi , PR China.
Jian
J
Sun
a Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University , Nanchang , Jiangxi , PR China.
Yue-Hai
YH
You
a Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University , Nanchang , Jiangxi , PR China.
Ji-Zong
JZ
Chen
a Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University , Nanchang , Jiangxi , PR China.
Guo-Dong
GD
Liu
a Jiangxi Key Laboratory of Organic Chemistry, Jiangxi Science and Technology Normal University , Nanchang , Jiangxi , PR China.
Qi
Q
Sun
D002384:Catalysis; D002851:Chromatography, High Pressure Liquid; D006865:Hydrogenation; D007700:Kinetics; D014500:Uracil Nucleotides / Q000138:chemical synthesis* / Q000302:isolation & purification
D014500:Uracil Nucleotides
4,5-dicyanoimidazole; 5-carboxy-2′-deoxynucleoside; P(V)–N activation; phosphoropiperidate; triphosphate