title: Access to 4,6-Diarylpicolinates via a Domino Reaction of Cyclic Sulfamidate Imines with Morita-Baylis-Hillman Acetates of Nitroolefins/Nitrodienes.
abstract: An interesting domino reaction of 5-membered cyclic sulfamidate imines with a variety of Morita-Baylis-Hillman acetates of nitroolefins/nitrodienes in the presence of DABCO as an organic base at 55 °C is reported for the first time. This new synthetic strategy provides a series of pharmacologically interesting 4,6-diarylpicolinates in high to excellent yields and allows several compatible functionalities on aryl rings. Moreover, the biologically interesting imidazo[1,2-a]pyridine (alpidem derivative) has been prepared in high chemical yield through a unique procedure.
authors.affiliation: Discipline of Chemistry, Indian Institute of Technology Indore , Simrol, Indore, 452020 Madhya Pradesh, India.
authors.forename: Debashis
authors.initials: D
authors.lastname: Majee
authors.affiliation: Discipline of Chemistry, Indian Institute of Technology Indore , Simrol, Indore, 452020 Madhya Pradesh, India.
authors.forename: Soumen
authors.initials: S
authors.lastname: Biswas
authors.affiliation: Discipline of Chemistry, Indian Institute of Technology Indore , Simrol, Indore, 452020 Madhya Pradesh, India.
authors.forename: Shaikh M
authors.initials: SM
authors.lastname: Mobin
authors.affiliation: Discipline of Chemistry, Indian Institute of Technology Indore , Simrol, Indore, 452020 Madhya Pradesh, India.
authors.forename: Sampak
authors.initials: S
authors.lastname: Samanta