title: Association between mild traumatic brain injury and mental health problems and self-reported cognitive dysfunction in Iraq and Afghanistan Veterans.
abstract: The Department of Veterans Affairs traumatic brain injury (TBI) screening program is intended to detect and expedite treatment for TBI and postconcussive symptoms. Between April 14, 2007, and May 31, 2012, of 66,089 Iraq and Afghanistan Veterans who screened positive on first-level TBI screening and later completed comprehensive TBI evaluation that includes the Neurobehavioral Symptoms Inventory, 72% reported moderate to very severe cognitive impairment (problems with attention, concentration, memory, etc.) that interfered with daily activities. This included 42% who were found not to have sustained combat-related mild TBI (mTBI). In contrast, 70.0% received a posttraumatic stress disorder (PTSD) diagnosis and 45.8% received a depression diagnosis. Compared with Veterans without mTBI, PTSD, or depression diagnoses, the lowest risk for self-reported cognitive impairment was in Veterans with confirmed mTBI only; a greater risk was found in those with PTSD diagnoses, with the greatest risk in Veterans with PTSD, depression, and confirmed mTBI, suggesting only a weakly additive effect of mTBI. These findings suggest that Veterans with multiple mental health comorbidities, not just those with TBI, report moderate to very severe cognitive impairment. Mental health treatment for conditions such as PTSD and depression (with or without TBI) may result in improvements in cognitive functioning and/or include assessment and support for Veterans experiencing cognitive problems.
authors.affiliation: San Francisco Department of Veterans Affairs (VA) Health Care System, San Francisco, CA;
authors.forename: Karen H
authors.initials: KH
authors.lastname: Seal
authors.forename: Daniel
authors.initials: D
authors.lastname: Bertenthal
authors.forename: Kristin
authors.initials: K
authors.lastname: Samuelson
authors.forename: Shira
authors.initials: S
authors.lastname: Maguen
authors.forename: Sant
authors.initials: S
authors.lastname: Kumar
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Vasterling
mesh_terms: D000293:Adolescent; D000328:Adult; D055826:Afghan Campaign 2001-; D001924:Brain Concussion / Q000175:diagnosis / Q000453:epidemiology* / Q000523:psychology; D060825:Cognitive Dysfunction / Q000453:epidemiology* / Q000209:etiology; D003863:Depression / Q000175:diagnosis / Q000453:epidemiology*; D005260:Female; D006801:Humans; D054542:Iraq War, 2003-2011; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D015995:Prevalence; D012189:Retrospective Studies; D057566:Self Report; D013313:Stress Disorders, Post-Traumatic / Q000175:diagnosis / Q000453:epidemiology*; D014481:United States; D014728:Veterans / Q000523:psychology*; D055815:Young Adult
keywords: Veterans; cognitive dysfunction; concussion; depression; mental health; mild traumatic brain injury; population-based screening; postdeployment; posttraumatic stress disorder; primary care; recovery expectations