title: Depression moderates the associations between beliefs about medicines and medication adherence in patients with rheumatoid arthritis: Cross-sectional study.
abstract: The 'necessity-concerns framework' postulates that patients' adherence behaviour is influenced by beliefs about the necessity and the concerns patients have regarding their prescribed medicines. We hypothesized that depression moderates the associations between beliefs about medicines and medication adherence among people with rheumatoid arthritis. Using multivariate logistic regression, we observed that people experiencing more depressive symptoms showed stronger associations between necessity beliefs and adherence as well as attenuated associations between concerns and adherence, respectively, in a cross-sectional sample ( N = 361). Thus, depression moderates the associations postulated in the 'necessity-concerns framework' in a differential way in people with rheumatoid arthritis.
authors.affiliation: 1 University of Regensburg, Germany.
authors.forename: Susanne
authors.initials: S
authors.lastname: Brandstetter
authors.affiliation: 1 University of Regensburg, Germany.
authors.forename: Gertraud
authors.initials: G
authors.lastname: Riedelbeck
authors.affiliation: 1 University of Regensburg, Germany.
authors.forename: Mark
authors.initials: M
authors.lastname: Steinmann
authors.affiliation: 1 University of Regensburg, Germany.
authors.forename: Julika
authors.initials: J
authors.lastname: Loss
authors.affiliation: 2 Asklepios Medical Center Bad Abbach, Germany.
authors.forename: Boris
authors.initials: B
authors.lastname: Ehrenstein
authors.affiliation: 1 University of Regensburg, Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Apfelbacher
mesh_terms: D000328:Adult; D000368:Aged; D001172:Arthritis, Rheumatoid / Q000188:drug therapy* / Q000523:psychology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000523:psychology*; D003866:Depressive Disorder / Q000523:psychology*; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D008297:Male; D055118:Medication Adherence / Q000523:psychology*; D008875:Middle Aged
keywords: beliefs about medicines; depression; medication adherence; rheumatoid arthritis