title: Foveal Thickness Alterations in Patients with Migraine.
abstract: OBJECTIVE
  To investigate the alterations in foveal retinal thickness (FT) values in patients with migraine and to reveal the correlations between FT and clinical characteristics of migraine disease.
  
  
  METHODS
  This study included sixty-eight eyes of 34 migraine patients [twenty-eight eyes of 14 patients with aura (group 1), and forty eyes of 20 patients without aura (group 2)] and forty eyes of 20 healthy volunteer who served as the control group (group 3). FT values were measured by optical coherence tomography (OCT) in each group.
  
  
  RESULTS
  Mean age of patients in group 1, 2, and 3 was 34.0± 6.82, 35.2±10.12, and 35.1± 6.85 years, respectively (p=0.84). Mean FT was 211.07±7.36, 220.0±12.01, and 221.85±12.27 in groups 1, 2, and 3, respectively. There was statistically significance among the group 1-2 and 1-3 (p=0.002 and p< 0.001). There was no statistically significance between group 2-3 (p=0.88).
  
  
  CONCLUSIONS
  This study suggests that in particular migraine with aura may lead to a reduction in FT values. This finding can be explained by the blood flow decrease theory in migraine; however larger studies seem mandatory.
authors.affiliation: Gozde Kisla Hospital, Eye Clinic, Malatya, Turkey.
authors.forename: Cem
authors.initials: C
authors.lastname: Cankaya
authors.affiliation: Department of Neurology, Faculty of Medicine, University of Inonu, Malatya, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Tecellioglu
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003430:Cross-Sectional Studies; D005260:Female; D005584:Fovea Centralis / Q000098:blood supply / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D020325:Migraine with Aura / Q000000981:diagnostic imaging / Q000503:physiopathology*; D020326:Migraine without Aura / Q000000981:diagnostic imaging / Q000503:physiopathology*; D011237:Predictive Value of Tests; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology*; D041623:Tomography, Optical Coherence
keywords: Foveal thickness; migraine; optical coherence tomography