title: Osteochondral Allograft Transplantation in the Knee.
abstract: The technique of osteochondral allograft (OCA) transplantation has been used to treat a wide spectrum of cartilage deficiencies in the knee. Its use has been supported by basic science and clinical studies that show it is a safe and effective treatment option. What sets fresh OCA transplantation apart from other cartilage procedures in the knee, is the ability to treat large defects with mature hyaline cartilage. Studies looking at transplantation of fresh OCAs in the general population have shown reliable pain relief and return to activities of daily living. Reports of cartilage injuries in athletes have risen over the years and more research is needed in evaluating the successfulness of OCA transplantation in the athletic population.
authors.affiliation: *Kerlan-Jobe Orthopaedic Clinic, Los Angeles †Division of Orthopaedic Surgery, Scripps Clinic ‡Department of Bioengineering, University of California-San Diego, La Jolla, CA.
authors.forename: Ioannis C
authors.initials: IC
authors.lastname: Zouzias
authors.forename: William D
authors.initials: WD
authors.lastname: Bugbee
mesh_terms: D016025:Bone Transplantation / Q000534:rehabilitation; D002358:Cartilage, Articular / Q000000981:diagnostic imaging / Q000293:injuries / Q000601:surgery; D005269:Femur / Q000601:surgery; D006801:Humans; D051457:Hyaline Cartilage / Q000637:transplantation*; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D014184:Transplantation, Homologous / Q000534:rehabilitation