title: Appetite-Enhancing Effects: The Influence of Concentrations of Benzylacetone and trans-Cinnamaldehyde and Their Inhalation Time, as Well as the Effect of Aroma, on Body Weight in Mice.
abstract: Benzylacetone has appetite-enhancing and locomotor-reducing effects. The effective doses for these two outcomes overlap, and the weight gain of mice exposed to benzylacetone is caused by both appetite-enhancement and a reduction in locomotor activity. The appetite-enhancing effects of trans-cinnamaldehyde and benzylacetone have been reported previously. In this study, these appetite-enhancing effects were seen in mice after short-term, high-dose exposure.
authors.affiliation: Department of Pharmacognosy, Graduate School of Pharmaceutical Sciences, Kyoto University.
authors.forename: Kakuyou
authors.initials: K
authors.lastname: Ogawa
authors.forename: Michiho
authors.initials: M
authors.lastname: Ito
mesh_terms: D000096:Acetone / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D000171:Acrolein / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000494:pharmacology; D000280:Administration, Inhalation; D000818:Animals; D001066:Appetite / Q000187:drug effects*; D019167:Appetite Stimulants / Q000008:administration & dosage* / Q000494:pharmacology; D001835:Body Weight / Q000187:drug effects; D004305:Dose-Response Relationship, Drug; D008297:Male; D051379:Mice; D009043:Motor Activity / Q000187:drug effects
chemical_list: D019167:Appetite Stimulants; C531285:benzyl acetone; D000096:Acetone; D000171:Acrolein; C012843:cinnamaldehyde