title: Genetic and epigenetic study of ALS-discordant identical twins with double mutations in SOD1 and ARHGEF28.
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Ming
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Zhengrui
authors.initials: Z
authors.lastname: Xi
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Mahdi
authors.initials: M
authors.lastname: Ghani
authors.affiliation: Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
authors.forename: Peixin
authors.initials: P
authors.lastname: Jia
authors.affiliation: Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
authors.forename: Mrinal
authors.initials: M
authors.lastname: Pal
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Karolina
authors.initials: K
authors.lastname: Werynska
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Danielle
authors.initials: D
authors.lastname: Moreno
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Christine
authors.initials: C
authors.lastname: Sato
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liang
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Janice
authors.initials: J
authors.lastname: Robertson
authors.affiliation: Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
authors.forename: Arturas
authors.initials: A
authors.lastname: Petronis
authors.affiliation: Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Lorne
authors.initials: L
authors.lastname: Zinman
authors.affiliation: Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
authors.forename: Ekaterina
authors.initials: E
authors.lastname: Rogaeva
mesh_terms: D000690:Amyotrophic Lateral Sclerosis; D002170:Canada; D019175:DNA Methylation; D006801:Humans; D007558:Italy / Q000208:ethnology; D008875:Middle Aged; D009154:Mutation / Q000235:genetics*; D064067:Rho Guanine Nucleotide Exchange Factors / Q000235:genetics*; D000072105:Superoxide Dismutase-1 / Q000235:genetics*; D014430:Twins, Monozygotic / Q000235:genetics*
chemical_list: C576601:ARHGEF3 protein, human; D064067:Rho Guanine Nucleotide Exchange Factors; C000606290:SOD1 protein, human; D000072105:Superoxide Dismutase-1
keywords: ALS; GENETICS