title: Sigmoid colon carcinoma with focal neuroendocrine differentiation associated with ulcerative colitis: A case report.
abstract: BACKGROUND
  Neuroendocrine tumors of the colon and rectum are relatively rare compared to sporadic colorectal carcinoma. There are few reports of neuroendocrine tumors of the colon and rectum in patients with ulcerative colitis.
  
  
  METHODS
  A patient with sigmoid colon carcinoma with focal neuroendocrine features is presented. A 32-year-old man, who had been followed for ulcerative colitis for 14 years, was found to have carcinoma of the sigmoid colon on routine annual colonoscopy, and he underwent laparoscopic total colectomy. Pathologic examination showed sigmoid colon adenocarcinoma with focal neuroendocrine features.
  
  
  CONCLUSIONS
  Most colorectal carcinomas associated with inflammatory bowel disease are histologically similar to the sporadic type, and tumors with neuroendocrine features are very unusual.
  
  
  CONCLUSIONS
  Very rare case of sigmoid colon carcinoma with neuroendocrine features arising in a patient with UC was described.
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: m03097kr@jichi.ac.jp.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Rifu
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: kjkoinum@jichi.ac.jp.
authors.forename: Koji
authors.initials: K
authors.lastname: Koinuma
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: hisahorie@jichi.ac.jp.
authors.forename: Hisanaga
authors.initials: H
authors.lastname: Horie
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: mittyone2000@yahoo.co.jp.
authors.forename: Mitsuaki
authors.initials: M
authors.lastname: Morimoto
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: y.kono@jichi.ac.jp.
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Kono
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: kuritama@jichi.ac.jp.
authors.forename: Makiko
authors.initials: M
authors.lastname: Tahara
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: naruchan@jichi.ac.jp.
authors.forename: Yasunaru
authors.initials: Y
authors.lastname: Sakuma
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: hosoyo@jichi.ac.jp.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Hosoya
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: kitayama@jichi.ac.jp.
authors.forename: Joji
authors.initials: J
authors.lastname: Kitayama
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: alefor@jichi.ac.jp.
authors.forename: Alan Kawarai
authors.initials: AK
authors.lastname: Lefor
authors.affiliation: Department of Surgery, Jichi Medical University, Japan. Electronic address: sata@jichi.ac.jp.
authors.forename: Naohiro
authors.initials: N
authors.lastname: Sata
authors.affiliation: Department of Pathology, Jichi Medical University, Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Suzuki
authors.affiliation: Department of Pathology, Jichi Medical University, Japan.
authors.forename: Noriyoshi
authors.initials: N
authors.lastname: Fukushima
keywords: Case report; Colorectal cancer; Neuroendocrine tumor; Ulcerative colitis