title: Associations between Diet Behaviors and Measures of Glycemia, in Clinical Setting, in Obese Adolescents.
abstract: To determine the influence of dietary behaviors, assessed in a clinical setting, on measures of glycemia in overweight and obese adolescents.
  
  
  
  The study is a retrospective, cross-sectional chart review. Eligible participants were overweight youth (N = 146, age 9-21 years) who attended the Youth Diabetes Prevention Clinic in Indianapolis, IN. Glycemic status was assessed during a 2-hour oral glucose tolerance test (OGTT). In the Bright Futures Questionnaire, a recommended clinical tool for assessing unhealthy behaviors in youth, nutrition-specific questions were modified to quantify dietary habits. Associations between dietary habits and measures of glycemia were determined using multiple linear regression models. Skewed data are presented as geometric means and 95% confidence intervals.
  
  
  
  Of the 146 adolescents who were assessed [60% girls, age 13.7 years (13.3, 14.0), BMI 33.9 kg/m(2) (33.3, 34.5)], 40% were diagnosed with prediabetes. Higher intake of dessert foods was associated with increased glucose levels at 2 hours following the OGTT (β = 0.23, p = 0.004), and higher intake of packaged snack foods was associated with elevated levels of hemoglobin A1c (β = 0.04, p = 0.04), independent of adiposity.
  
  
  
  In obese youth, high intakes of dessert and packaged snack items were associated with elevated concentrations of glucose at 2 hours following the OGTT and hemoglobin A1c. Findings demonstrate the usefulness of a modified Bright Futures Questionnaire, used in a clinical setting, for identifying dietary behaviors associated with hyperglycemia in obese adolescents. ClinicalTrials.gov registration number: NCT02535169.
authors.affiliation: 1 Department of Nutrition Science, Purdue University , West Lafayette, IN.
authors.forename: Kelly A
authors.initials: KA
authors.lastname: Wagner
authors.affiliation: 1 Department of Nutrition Science, Purdue University , West Lafayette, IN.
authors.forename: Seth M
authors.initials: SM
authors.lastname: Armah
authors.affiliation: 2 Youth Diabetes Prevention Clinic, IU School of Medicine, Indiana University , Indianapolis, IN.
authors.forename: Lisa G
authors.initials: LG
authors.lastname: Smith
authors.affiliation: 2 Youth Diabetes Prevention Clinic, IU School of Medicine, Indiana University , Indianapolis, IN.
authors.forename: Julie
authors.initials: J
authors.lastname: Pike
authors.affiliation: 3 Department of Biostatistics, Indiana University School of Medicine , Indianapolis, IN.
authors.forename: Wanzhu
authors.initials: W
authors.lastname: Tu
authors.affiliation: 1 Department of Nutrition Science, Purdue University , West Lafayette, IN.
authors.forename: Wayne W
authors.initials: WW
authors.lastname: Campbell
authors.affiliation: 4 Epidemiology Program, University of Hawaii Cancer Center , Honolulu, HI.
authors.forename: Carol J
authors.initials: CJ
authors.lastname: Boushey
authors.affiliation: 5 Department of Pediatrics, Indiana University School of Medicine , Indianapolis, IN.
authors.forename: Tamara S
authors.initials: TS
authors.lastname: Hannon
authors.affiliation: 1 Department of Nutrition Science, Purdue University , West Lafayette, IN.
authors.forename: Nana
authors.initials: N
authors.lastname: Gletsu-Miller
mesh_terms: D050154:Adiposity; D000293:Adolescent; D001786:Blood Glucose / Q000378:metabolism*; D002648:Child; D003430:Cross-Sectional Studies; D004032:Diet / Q000009:adverse effects*; D005247:Feeding Behavior / Q000523:psychology*; D005260:Female; D005951:Glucose Tolerance Test; D006442:Glycated Hemoglobin / Q000378:metabolism*; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D007196:Indiana / Q000453:epidemiology; D008297:Male; D009752:Nutritional Status; D063766:Pediatric Obesity / Q000097:blood / Q000150:complications* / Q000453:epidemiology; D011236:Prediabetic State / Q000097:blood / Q000209:etiology* / Q000517:prevention & control; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human