title: Correlating Preoperative Imaging with Histologic Subtypes of Renal Cell Carcinoma and Common Mimickers.
abstract: Renal cell carcinoma (RCC) consists of distinct subtypes that have unique pathologic and imaging features as well as specific cytogenetic and molecular characteristics. As the prognosis and therapeutic strategies may differ for each subtype, correlation of the preoperative imaging with the pathologic findings is of great clinical relevance. In addition, differentiation of RCC from benign entities is ideal in order to prevent overtreatment. However, a noninvasive diagnosis with imaging alone is not always straightforward due to the overlapping appearance of RCC with benign lesions such as fat-poor angiomyolipoma and oncocytoma. With new imaging modalities, there have been significant improvements in correlating preoperative imaging with pathologic characteristics. These new discoveries are able to aid in a more specific, noninvasive, diagnosis that in turn helps direct patient management.
authors.affiliation: Department of Pathology, University of Alabama at Birmingham, NP 3550, 1802 6th Avenue South, Birmingham, AL, 35249, USA. jgordetsky@uabmc.edu.|Department of Urology, University of Alabama at Birmingham, Birmingham, AL, USA. jgordetsky@uabmc.edu.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Gordetsky
authors.affiliation: Department of Radiology, The University of Alabama at Birmingham, JTN 357, 619 19th Street South, Birmingham, AL, 35294, USA.
authors.forename: Jessica
authors.initials: J
authors.lastname: Zarzour
mesh_terms: D018249:Adenoma, Oxyphilic / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D018207:Angiomyolipoma / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002292:Carcinoma, Renal Cell / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D003937:Diagnosis, Differential; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000601:surgery; D011300:Preoperative Care
keywords: Angiomyolipoma; Oncocytoma; Pathology; Radiology; Renal cell carcinoma