title: Kleine-Levin Syndrome.
abstract: Kleine-Levin syndrome is a rare recurrent hypersomnia associated with symptoms of behavioral and cognitive impairment. This article reviews common presenting symptoms, differential diagnosis, diagnostic workup, and potential treatment options. Current updates on functional imaging studies and long-term neuropsychological studies are reviewed.
authors.affiliation: Sleep Medicine, Stanford University, Redwood City, CA, USA. mmiglis@stanford.edu.
authors.forename: Mitchell G
authors.initials: MG
authors.lastname: Miglis
authors.affiliation: Sleep Medicine, Stanford University, Redwood City, CA, USA.
authors.forename: Christian
authors.initials: C
authors.lastname: Guilleminault
mesh_terms: D000818:Animals; D003937:Diagnosis, Differential; D055724:Electrophysiological Phenomena; D006801:Humans; D017593:Kleine-Levin Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D009483:Neuropsychological Tests; D011379:Prognosis
keywords: Adolescent; Derealization; Hyperphagia; Hypersexuality; Hypersomnia; Kleine-Levin syndrome; Sleep disorder