title: Exceeding the limits - Cdc45 overexpression turns bad.
authors.affiliation: a DNA Replication Group, Institute of Clinical Sciences, Imperial College London , London , UK.|b bMRC Clinical Sciences Centre , Du Cane Road, London , UK.
authors.forename: Christian
authors.initials: C
authors.lastname: Speck
mesh_terms: D018797:Cell Cycle Proteins / Q000235:genetics; D004265:DNA Helicases; D004261:DNA Replication; D064110:Minichromosome Maintenance Proteins; D018741:Replication Origin
chemical_list: D018797:Cell Cycle Proteins; D004265:DNA Helicases; D064110:Minichromosome Maintenance Proteins
keywords: Apoptosis; CMG helicase; Cdc45; DNA Replication; MCM2-7; RPA; genome stability; origin firing; replication fork; single stranded DNA