title: Jones-matrix mapping of complex degree of mutual anisotropy of birefringent protein networks during the differentiation of myocardium necrotic changes.
abstract: The azimuthally stable method of Jones-matrix mapping of histological sections of myocardium tissue biopsy using spatial-frequency selection of the mechanisms of linear and circular birefringence is proposed. Correlation parameter-the complex degree of mutual anisotropy-and its diagnostic application are analytically substantiated. The method of measuring the complex degree of mutual-anisotropy coordinate distributions using spatial filtration of their high- and low-frequency components is developed. The interconnections between such distributions and parameters of linear and circular birefringence of myocardium tissue histological sections are defined. The comparative investigations of coordinate distributions of the complex degree of mutual anisotropy formed by fibrillar networks of myocardium tissues of different necrotic states (dead due to coronary heart disease and acute coronary insufficiency) are performed. The values and ranges of change of the statistical (moments of the first-fourth order) parameters of coordinate distributions of the complex degree of mutual anisotropy are defined. The objective criteria of cause of death differentiation are determined.
authors.forename: Yu A
authors.initials: YA
authors.lastname: Ushenko
authors.forename: V T
authors.initials: VT
authors.lastname: Bachynsky
authors.forename: O Ya
authors.initials: OY
authors.lastname: Vanchulyak
authors.forename: A V
authors.initials: AV
authors.lastname: Dubolazov
authors.forename: M S
authors.initials: MS
authors.lastname: Garazdyuk
authors.forename: V A
authors.initials: VA
authors.lastname: Ushenko
mesh_terms: D016880:Anisotropy; D001718:Birefringence; D005583:Fourier Analysis; D006801:Humans; D008859:Microscopy, Polarization / Q000379:methods*; D009206:Myocardium / Q000473:pathology*; D011506:Proteins / Q000032:analysis*; D012542:Scattering, Radiation
chemical_list: D011506:Proteins