title: Comparison of MRI features of pathologically proven hepatocellular carcinoma between patients with hepatitis B and hepatitis C infection.
abstract: OBJECTIVE
  To compare MRI features of pathologically-proven hepatocellular carcinoma (HCC) between patients with hepatitis B (HBV) and hepatitis C (HCV) infection.
  
  
  METHODS
  Two radiologists assessed 51 confirmed HCCs on MRI in HBV (n=18) or HCV (n=33) patients; a third, more experienced, radiologist resolved discrepancies.
  
  
  RESULTS
  Arterial hyperenhancement occurred more frequently in HCV (90.9% vs. 66.7%; P=.032), DWI/T2WI hyperintensity more frequently in HBV [(DWI: 78.6% vs. 45.8%, T2WI: 77.8% vs. 48.5%; P=.073-0.088)]. Tumors were larger in HBV (P≤.016). Washout, pseudocapsule, homogeneity, circumscribed margins, lipid, iron, and visually low ADC were not different.
  
  
  CONCLUSIONS
  Larger studies are required to confirm these preliminary findings.
authors.affiliation: Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, New York, NY, 10016. Electronic address: diane.belvin@gmail.com.
authors.forename: Diane
authors.initials: D
authors.lastname: Dunst
authors.affiliation: Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, New York, NY, 10016. Electronic address: Justin.ream@nyumc.org.
authors.forename: Justin M
authors.initials: JM
authors.lastname: Ream
authors.affiliation: Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, New York, NY, 10016. Electronic address: victoria.khalef@gmail.com.
authors.forename: Victoria
authors.initials: V
authors.lastname: Khalef
authors.affiliation: Department of Pathology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, New York, NY, 10016. Electronic address: Cristina.hajdu@nyumc.org.
authors.forename: Cristina H
authors.initials: CH
authors.lastname: Hajdu
authors.affiliation: Department of Radiology, NYU School of Medicine, NYU Langone Medical Center, 550 First Avenue, New York, NY, 10016. Electronic address: Andrew.rosenkrantz@nyumc.org.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Rosenkrantz
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D006528:Carcinoma, Hepatocellular / Q000000981:diagnostic imaging* / Q000821:virology; D005260:Female; D019694:Hepatitis B, Chronic / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D008113:Liver Neoplasms / Q000000981:diagnostic imaging* / Q000821:virology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies
keywords: Hepatitis B; Hepatitis C; Hepatocellular carcinoma; MRI