title: Bidirectional Data Collaborations in Distributed Research.
abstract: BACKGROUND
  The need for collaborations with bidirectional data exchange within and across distributed research networks has increased.
  This commentary will present currently publically available activities including the Sentinel Initiative, the Patient-Centered Outcomes Research Network (PCORnet), and the NIH Research Collaboratory.
  Even with the advances made in this arena, several technical and governance challenges remain including the evolution of clinically rich data sources and modes of care, availability of longitudinal data resources through data linkage, and the processes to share data and link data resources while ensuring privacy and proprietary control of data.
  
  
  CONCLUSIONS
  These activities will require enhanced levels of trust between entities involved in the delivery of healthcare (Trust 2.0) in addition to the trust health plans and health systems have with patients (Trust 1.0). Recent public funding announcements and public access to data resources will likely improve the landscape of bidirectional data collaborations in distributed research.
authors.affiliation: HealthCore, Inc.
authors.forename: Kevin
authors.initials: K
authors.lastname: Haynes
authors.affiliation: HealthCore, Inc.
authors.forename: Nandini
authors.initials: N
authors.lastname: Selvam
authors.affiliation: HealthCore, Inc.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Cziraky
keywords: Data Use and Quality; Electronic Health Record (EHR); Governance; Health Information Technology; Informatics; Patient-Centered Outcomes Research (PCOR); Research Networks