title: Universal influenza vaccines: a realistic option?
abstract: The extensive antigenic drift displayed by seasonal influenza viruses and the risk of pandemics caused by newly emerging antigenically distinct influenza A viruses of novel subtypes has raised considerable interest in the development of so-called universal influenza vaccines. We review options for the development of universal flu vaccines and discuss progress that has been made recently.
authors.affiliation: Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: R D
authors.initials: RD
authors.lastname: de Vries
authors.affiliation: Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands.
authors.forename: A F
authors.initials: AF
authors.lastname: Altenburg
authors.affiliation: Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands. Electronic address: g.rimmelzwaan@erasmusmc.nl.
authors.forename: G F
authors.initials: GF
authors.lastname: Rimmelzwaan
mesh_terms: D000914:Antibodies, Viral; D006801:Humans; D009980:Influenza A virus / Q000145:classification / Q000276:immunology*; D007252:Influenza Vaccines / Q000276:immunology*; D007251:Influenza, Human / Q000453:epidemiology / Q000517:prevention & control*; D058873:Pandemics / Q000517:prevention & control*; D012621:Seasons
chemical_list: D000914:Antibodies, Viral; D007252:Influenza Vaccines
keywords: Antibodies; Immunity; Influenza; T lymphocytes; Universal vaccine; Virus vectors