title: Highly regioselective meta arylation of oxalyl amide-protected β-arylethylamine via the Catellani reaction.
abstract: The first bidentate directing group assisted highly selective meta arylation of β-arylethylamine derivatives via palladium/norbornene catalysis is reported, and the range of aryl iodides for the oxalyl amide assisted meta-selective arylation reactions is broadest yet reported. This meta arylation also proceeds well with thiophene derivatives, giving the corresponding products in satisfactory yields. And three-step functionalization of arylethyloxalamide with three different functional groups is successfully performed.
authors.affiliation: Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China. yszhao@suda.edu.cn.
authors.forename: Jian
authors.initials: J
authors.lastname: Han
authors.forename: Li
authors.initials: L
authors.lastname: Zhang
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhu
authors.forename: Yongxiang
authors.initials: Y
authors.lastname: Zheng
authors.forename: Xiaolan
authors.initials: X
authors.lastname: Chen
authors.forename: Zhi-Bin
authors.initials: ZB
authors.lastname: Huang
authors.forename: Da-Qing
authors.initials: DQ
authors.lastname: Shi
authors.forename: Yingsheng
authors.initials: Y
authors.lastname: Zhao