title: Introduction of Inactivated Poliovirus Vaccine in National Immunization Program and Polio Endgame Strategy.
abstract: The World Health Organization declared India among other 10 countries in South East Region - as 'polio-free' in 2014. Since then, the Government of India (GoI) has scaled up its initiatives against polio endgame which targets virus eradication and sequential withdrawal of type 2 virus from oral polio vaccine (OPV). However, prior to choosing the switch from trivalent OPV (t-OPV) to bivalent OPV (b-OPV), it was suggested to include inactivated poliovirus vaccine (IPV) in the national immunization schedule to protect vaccine naïve population against type 2 poliovirus. The GoI declared introduction of single dose of intramuscular IPV at 14 weeks since October 2015. In addition, anticipating the scarcity of IPV at present in India, GoI also recommended two intradermal doses of IPV in few states since April 2016. This review discusses the programmatic implications of these strategies along with recommendations by the Advisory Committee on Vaccines and Immunization Practices of Indian Academy of Pediatrics (IAP-ACVIP) on polio endgame strategy.
authors.affiliation: Indian Academy of Pediatrics (IAP) Advisory Committee on Vaccines and Immunization Practices (ACVIP), Mumbai, India. Correspondence to: Dr Vipin M Vashishtha, Convener, IAP-ACVIP. vipinipsita@gmail.com.
authors.forename: Vipin M
authors.initials: VM
authors.lastname: Vashishtha
authors.forename: Jaydeep
authors.initials: J
authors.lastname: Choudhary
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Yadav
authors.forename: Jeeson C
authors.initials: JC
authors.lastname: Unni
authors.forename: Pramod
authors.initials: P
authors.lastname: Jog
authors.forename: Sachidanand S
authors.initials: SS
authors.lastname: Kamath
authors.forename: Anupam
authors.initials: A
authors.lastname: Sachdeva
authors.forename: Sanjay
authors.initials: S
authors.lastname: Srirampur
authors.forename: Baldev
authors.initials: B
authors.lastname: Prajapati
authors.forename: Bakul J
authors.initials: BJ
authors.lastname: Parekh
mesh_terms: D060740:Disease Eradication / Q000379:methods*; D014943:Global Health; D006801:Humans; D007115:Immunization Schedule; D007194:India; D007223:Infant; D011051:Poliomyelitis / Q000517:prevention & control*; D011054:Poliovirus Vaccine, Inactivated
chemical_list: D011054:Poliovirus Vaccine, Inactivated