title: RELMs in the Realm of Helminths.
abstract: Resistin-like molecule (RELM) proteins are essential for immunity to helminths. Recently, Chen and collaborators identified a dominant role for RELMα over RELMβ in host immunity to Nippostrongylus brasiliensis using a double knockout system. The study highlighted how important and yet divergent the contributions of these proteins are in the control of helminth infections.
authors.affiliation: Division of Immunology, Institute of Infectious Diseases and Molecular Medicine, University of Cape Town, Cape Town, South Africa. Electronic address: wghorsnell@gmail.com.
authors.forename: William G C
authors.initials: WGC
authors.lastname: Horsnell
authors.affiliation: Fundamental and Applied Research for Animal and Health (FARAH), Immunology-Vaccinology, University of Liege, Liege, Belgium.
authors.forename: Benjamin G
authors.initials: BG
authors.lastname: Dewals
mesh_terms: D000818:Animals; D006373:Helminthiasis / Q000276:immunology* / Q000469:parasitology; D006376:Helminths; D006790:Host-Parasite Interactions / Q000276:immunology*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000378:metabolism*; D051379:Mice
chemical_list: D036341:Intercellular Signaling Peptides and Proteins