title: Kawasaki disease with Glucose-6-Phosphate Dehydrogenase deficiency, case report.
abstract: Kawasaki disease (KD) is an acute, self-limited vasculitis of unknown etiology that occurs predominantly in infants and children younger than 5 years of age. Coronary artery abnormalities are the most serious complication. Based on the literatures infusion of Intravenous Immunoglobulin of 2 g/kg and a high dose of oral aspirin up to 100 mg/kg/day are the standard treatment for Kawasaki disease in the acute stage, and should be followed by antiplatelet dose of aspirin for thrombocytosis. Glucose-6-Phosphate Dehydrogenase (G6PD) deficiency is an inherited X-linked hereditary disorder, and aspirin can induce hemolysis in patients with G6PD deficiency. We report a case of a 5 year and 8 month old male with KD and G6PD deficiency.
authors.affiliation: Pharmacy Department, Saad Specialist Hospital, Alkhobar 31952, Saudi Arabia.
authors.forename: Hesham Radi
authors.initials: HR
authors.lastname: Obeidat
authors.affiliation: Pediatric and Neonatology Department, Saad Specialist Hospital, Alkhobar 31952, Saudi Arabia.
authors.forename: Sahar
authors.initials: S
authors.lastname: Al-Dossary
authors.affiliation: Pharmacy Department, Saad Specialist Hospital, Alkhobar 31952, Saudi Arabia.
authors.forename: Abdulsalam
authors.initials: A
authors.lastname: Asseri
keywords: Aspirin; G6PD; Kawasaki disease