title: [Surgery for pulmonary metastases from colorectal cancer: Predictive factors for survival].
abstract: BACKGROUND
  Colorectal cancer is the 3rd commonest cause of death from cancer: 5% of patients will develop lung metastases. The management of oligometastatic disease is based on the objective of optimal local control.
  
  
  BACKGROUND
  To date, no results from randomized control trials support the resection of pulmonary metastases in oligometastastic colorectal cancer patients. However, numerous series, mainly retrospective, report long-term survival for highly selected patients, with 5-year survival ranging from 45 to 65% in the most recent series. The consensual predictive factors of a good prognosis are: a disease free-interval>36 months, a number of metastases≤3, a normal level of carcino-embryonic antigen and the absence of hilar or mediastinal lymph node involvement.
  
  
  CONCLUSIONS
  Around 20 to 40% of patients will develop recurrence, probably linked to the presence of undetectable micrometastases. Therefore, experimental work is being undertaken to develop new treatment techniques such as isolated lung perfusion, radiofrequency ablation and stereotactic radiation therapy.
  
  
  CONCLUSIONS
  Highly selected patients suffering from colorectal cancer lung metastases could benefit from resection with improved survival and disease-control.
authors.affiliation: Service de chirurgie cardiovasculaire et thoracique, CHU Bocage central, université de Bourgogne, 14, rue Gaffarel, BP 77908, 21079 Dijon cedex, France. Electronic address: pierrebenoit.pages@chu-dijon.fr.
authors.forename: P-B
authors.initials: PB
authors.lastname: Pagès
authors.affiliation: Service de chirurgie thoracique, hôpital européen Georges-Pompidou, université Paris-Descartes, 75015 Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Le Pimpec-Barthes
authors.affiliation: Service de chirurgie cardiovasculaire et thoracique, CHU Bocage central, université de Bourgogne, 14, rue Gaffarel, BP 77908, 21079 Dijon cedex, France.
authors.forename: A
authors.initials: A
authors.lastname: Bernard
mesh_terms: D015179:Colorectal Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D003131:Combined Modality Therapy; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D018579:Patient Selection; D011013:Pneumonectomy / Q000401:mortality*; D011379:Prognosis; D012307:Risk Factors; D015996:Survival Rate
keywords: Facteurs prédictifs; Lung metastases; Multimodality treatment; Métastases pulmonaires; Predictive factors; Survie; Survival; Traitement multimodal