title: Coupling of the Decarboxylation of 2-Cyano-2-phenylpropanoic Acid to Large-Amplitude Motions: A Convenient Fuel for an Acid-Base-Operated Molecular Switch.
abstract: The decarboxylation of 2-cyano-2-phenylpropanoic acid is fast and quantitative when carried out in the presence of 1 molar equivalent of a [2]catenane composed of two identical macrocycles incorporating a 1,10-phenanthroline unit in their backbone. When decarboxylation is over, all of the catenane molecules have experienced large-amplitude motions from neutral to protonated catenane, and back again to the neutral form, so that they are ready to perform another cycle. This study provides the first example of the cyclic operation of a molecular switch at the sole expenses of the energy supplied by the substrate undergoing chemical transformation, without recourse to additional stimuli.
authors.affiliation: Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600, MB Eindhoven, The Netherlands.
authors.forename: José Augusto
authors.initials: JA
authors.lastname: Berrocal
authors.affiliation: Dipartimento di Chimica, Università di Roma La Sapienza and Istituto CNR di Metodologie Chimiche (IMC-CNR), Sezione Meccanismi di Reazione, P. le A. Moro 5, 00185, Roma, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: Biagini
authors.affiliation: Dipartimento di Chimica, Università di Roma La Sapienza and Istituto CNR di Metodologie Chimiche (IMC-CNR), Sezione Meccanismi di Reazione, P. le A. Moro 5, 00185, Roma, Italy.
authors.forename: Luigi
authors.initials: L
authors.lastname: Mandolini
authors.affiliation: Dipartimento di Chimica, Università di Roma La Sapienza and Istituto CNR di Metodologie Chimiche (IMC-CNR), Sezione Meccanismi di Reazione, P. le A. Moro 5, 00185, Roma, Italy. stefano.distefano@uniroma1.it.
authors.forename: Stefano
authors.initials: S
authors.lastname: Di Stefano
keywords: catenanes; chemical fuels; decarboxylation; molecular devices; molecular motions