title: Enantioselective Construction of Spirocyclic Oxindole Derivatives with Multiple Stereocenters via an Organocatalytic Michael/Aldol/Hemiacetalization Cascade Reaction.
abstract: An efficient organocatalytic Michael/aldol/hemiacetalization cascade reaction for construction of enantioenriched spirocyclic oxindoles fused with tetrahydropyrane has been developed. The desired highly functionalized 5',6'-dihydro-2'H,4'H-spiro[indoline-3,3'-pyran]-2-one derivatives containing multiple stereogenic centers were obtained in moderate to high chemical yields and with high stereoselectivities.
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Luyi
authors.initials: L
authors.lastname: Zhu
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Qiliang
authors.initials: Q
authors.lastname: Chen
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Shen
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Weihao
authors.initials: W
authors.lastname: Zhang
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Cong
authors.initials: C
authors.lastname: Shen
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Zeng
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Guofu
authors.initials: G
authors.lastname: Zhong