title: The Nocebo Effect.
abstract: A growing body of evidence is emerging for a phenomenon known as the nocebo effect. This is when a person is conditioned to expect a negative response, or to anticipate negative effects from an experience. These findings highlight the importantance of effective communication with patients and the influence that good anxiety and pain management control can have in improving treatment outcomes. The placebo effect has been widely researched, but new studies have shown that nocebo can have a greater effect than placebo The nocebo effect is prevalent in interactions between patients and healthcare workers. Research has demonstrated that if a patient deems a healthcare professional not to understand or believe them, this can cause distress, and the physiological effect can reduce the prognosis of treatment. It has also been demonstrated that patients who are anxious or expect pain during a procedure, feel more pain because of this negative expectation.
authors.forename: Lucy
authors.initials: L
authors.lastname: Horsfall
mesh_terms: D000700:Analgesics / Q000627:therapeutic use; D001007:Anxiety / Q000503:physiopathology / Q000523:psychology*; D001294:Attitude to Health; D002766:Cholecystokinin / Q000037:antagonists & inhibitors / Q000502:physiology; D016854:Dental Anxiety / Q000523:psychology; D006801:Humans; D009434:Neural Pathways / Q000502:physiology; D064786:Nocebo Effect; D010146:Pain / Q000503:physiopathology / Q000523:psychology*; D010465:Perception / Q000502:physiology; D015990:Placebo Effect
chemical_list: D000700:Analgesics; D002766:Cholecystokinin