title: Angiolymphoid Hyperplasia With Eosinophilia Within a Vascular Malformation: Case Report and Review of the Literature.
abstract: OBJECTIVE
  Angiolymphoid hyperplasia with eosinophilia (ALHE) is a rare, benign microvascular proliferation tumor. The etiology of ALHE is unknown, though some hypothesize it occurs in reaction to focal trauma. This study presents a case of AHLE within a vascular malformation, its treatment, and a review of the literature.
  
  
  METHODS
  A retrospective case report was performed with a 4-year follow-up. Medical records including clinic notes, radiography, operative reports, pathology, and long-term follow-up were reviewed.
  
  
  RESULTS
  Radiologic imaging revealed a vascular malformation with highly tortuous, corkscrew-shaped arterial vessels. Histology revealed midsized vessels with plump, epithelialized endothelium and focal areas of lymphocytic infiltrate punctuated with eosinophils, consistent with ALHE.
  
  
  CONCLUSIONS
  This case demonstrates a unique presentation of ALHE in association with vascular malformation. Initial physical exam lacked the classic dermatologic presentation of clusters of red-to-brown nodules; however, the corkscrew vessels lined by epithelized endothelial cells and eosinophilic infiltrate were pathognomonic for ALHE.
authors.affiliation: University of Kansas School of Medicine, Department of Otolaryngology, Kansas City, Kansas, USA.
authors.forename: Stefani C
authors.initials: SC
authors.lastname: Fontana
authors.affiliation: University of Kansas School of Medicine, Department of Otolaryngology, Kansas City, Kansas, USA.
authors.forename: Ashley
authors.initials: A
authors.lastname: Borgstadt
authors.affiliation: University of Kansas School of Medicine, Department of Pathology, Kansas City, Kansas, USA.
authors.forename: Garth R
authors.initials: GR
authors.lastname: Fraga
authors.affiliation: University of Kansas School of Medicine, Department of Radiology, Kansas City, Kansas, USA.
authors.forename: Alan R
authors.initials: AR
authors.lastname: Reeves
authors.affiliation: University of Kansas School of Medicine, Department of Otolaryngology, Kansas City, Kansas, USA bandrews@kumc.edu.
authors.forename: Brian T
authors.initials: BT
authors.lastname: Andrews
mesh_terms: D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery; D000072226:Computed Tomography Angiography; D005260:Female; D006801:Humans; D008875:Middle Aged; D054079:Vascular Malformations / Q000150:complications* / Q000000981:diagnostic imaging / Q000601:surgery
keywords: ALHE; angiolymphoid hyperplasia with eosinophilia; vascular malformation