title: Polyostotic Lymphoma in a Ferret (Mustela putorius furo).
abstract: An 8.5-year-old, neutered female ferret (Mustela putorius furo) was presented with tachypnoea, polyuria, polydipsia, anorexia and depression. Radiographs revealed multiple osteolytic lesions of the bone, characterized cytologically by the infiltration of medium- to large-sized lymphocytes. The animal was humanely destroyed and post-mortem examination revealed multifocal masses obliterating the bone marrow of the mandible, right and left humeri and femur, and consisting of an infiltrative population of neoplastic lymphocytes. Immunohistochemical labelling for CD3 and CD79a revealed a CD3-positive neoplastic population. A diagnosis of polyostotic T-cell lymphoma was made, which is the first report of this condition in a ferret.
authors.affiliation: School of Veterinary Science, The University of Queensland, 4343 Gatton Campus, Gatton, Queensland, Australia.
authors.forename: H
authors.initials: H
authors.lastname: Long
authors.affiliation: Clinica per Animali Esotici, Via Sandro Giovannini 51-53, Roma, Italy.
authors.forename: N
authors.initials: N
authors.lastname: di Girolamo
authors.affiliation: Clinica per Animali Esotici, Via Sandro Giovannini 51-53, Roma, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Selleri
authors.affiliation: School of Veterinary Science, The University of Queensland, 4343 Gatton Campus, Gatton, Queensland, Australia. Electronic address: c.palmieri@uq.edu.au.
authors.forename: C
authors.initials: C
authors.lastname: Palmieri
mesh_terms: D000818:Animals; D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D005289:Ferrets; D007150:Immunohistochemistry; D016399:Lymphoma, T-Cell / Q000662:veterinary*
chemical_list: D014408:Biomarkers, Tumor
keywords: ferret; immunohistochemistry; lymphoma; polyostotic