title: Ni(II)-Catalyzed C(sp(2))-H Alkynylation/Annulation with Terminal Alkynes under an Oxygen Atmosphere: A One-Pot Approach to 3-Methyleneisoindolin-1-one.
abstract: A nickel(II)-catalyzed alkynylation/annulation cascade via double C-H cleavage has been successfully achieved. This methodology adopted a removable N,O-bidentate directing group with a broad range of amide substrates and terminal alkynes being well tolerated. The catalytic system allowed for atom-economical and environmentally benign one-pot construction of the corresponding 3-methyleneisoindolin-1-one derivatives using O2 as the external oxidant.
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Xin-Xiang
authors.initials: XX
authors.lastname: Zheng
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Cong
authors.initials: C
authors.lastname: Du
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Zhao
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Xinju
authors.initials: X
authors.lastname: Zhu
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Jian-Feng
authors.initials: JF
authors.lastname: Suo
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Xin-Qi
authors.initials: XQ
authors.lastname: Hao
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Jun-Long
authors.initials: JL
authors.lastname: Niu
authors.affiliation: The College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Mao-Ping
authors.initials: MP
authors.lastname: Song