title: Neuroinflammation Regulates Cognitive Impairment in Socially Defeated Mice.
abstract: Impairments in memory and cognitive function are characteristic symptoms of stress-related disorders, but the relationship between stress and memory is complex. Recent findings suggest that hippocampal inflammatory processes contribute to spatial memory deficits in the rodent social defeat model that can be reversed by anti-inflammatory treatment with minocycline.
authors.affiliation: Fishberg Department of Neuroscience and Friedman Brain Institute; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, NY, NY 10029, USA.
authors.forename: Madeline L
authors.initials: ML
authors.lastname: Pfau
authors.affiliation: Fishberg Department of Neuroscience and Friedman Brain Institute. Electronic address: scott.russo@mssm.edu.
authors.forename: Scott J
authors.initials: SJ
authors.lastname: Russo
mesh_terms: D000818:Animals; D003071:Cognition / Q000502:physiology*; D003072:Cognition Disorders / Q000503:physiopathology*; D060825:Cognitive Dysfunction / Q000503:physiopathology*; D006624:Hippocampus / Q000503:physiopathology; D006801:Humans; D008568:Memory / Q000502:physiology*; D055495:Neurogenesis / Q000502:physiology
keywords: Inflammation; memory; neurogenesis; stress