title: Divergent Syntheses of Carbazole Alkaloids Clausenapin, Indizoline, Claulansine M, and Clausenaline D.
abstract: We described the first total syntheses of clausenapin, indizoline, claulansine M, and a novel synthetic route to clausenaline D via divergent method. Key steps involved TFAA-mediated intramolecular acylation to construct the carbazole core and subsequent Claisen rearrangement to generate key intermediates for further elaboration to target molecules.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Yizhen
authors.initials: Y
authors.lastname: Liu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Yanqin
authors.initials: Y
authors.lastname: Guo
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Feixiang
authors.initials: F
authors.lastname: Ji
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Dong
authors.initials: D
authors.lastname: Gao
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Chuanjun
authors.initials: C
authors.lastname: Song
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, People's Republic of China.
authors.forename: Junbiao
authors.initials: J
authors.lastname: Chang
mesh_terms: D000215:Acylation; D000470:Alkaloids / Q000138:chemical synthesis*; D002227:Carbazoles / Q000138:chemical synthesis*; D007202:Indicators and Reagents; D026121:Indole Alkaloids; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism
chemical_list: D000470:Alkaloids; D002227:Carbazoles; D007202:Indicators and Reagents; D026121:Indole Alkaloids; C000599397:clausenaline D