title: Spectrum of acute coronary syndrome in North Eastern India - A study from a major center.
abstract: OBJECTIVE
  Spectrum of acute coronary syndrome (ACS) has not been reported from North Eastern India. The present study was undertaken to study the clinical spectrum of ACS.
  
  
  METHODS
  We prospectively collected data of 704 ACS patients from February 2011 to August 2012 in Gauhati Medical College, a tertiary care center. We evaluated data on clinical characteristic, treatment, and outcome in ACS patients.
  
  
  RESULTS
  Of the 704 ACS patients, 72.4% presented with STEMI and 27.6% presented with NSTEMI/UA. Mean age of presentation was 56.5 years. Mean time to presentation was 11.42h and was higher in NSTEMI/UA than STEMI (12.86h vs. 9.98h, p<0.001). Treatment for STEMI did not differ much from NSTEMI/UA with ≥90% of patients in both groups receiving antiplatelets, statin, and anticoagulants. 39% of STEMI received thrombolytic therapy and percutaneous coronary intervention (PCI) rates were higher in STEMI. The 30-day mortality was found to be 10.22%, with STEMI having higher mortality than NSTEM/UA (11.76% vs. 6.18%, p=0.03).
  
  
  CONCLUSIONS
  These data represent the first reported study on spectrum of ACS in North Eastern India and has noted few key differences from the national registry CREATE, with greater percentage of STEMI patients, greater delay in seeking treatment, greater 30-day mortality, and lesser percentage of patients receiving reperfusion therapy.
authors.affiliation: Assistant Professor, Department of Cardiology, Gauhati Medical College, Guwahati, India. Electronic address: farhiniqbal@rediffmail.com.
authors.forename: Farhin
authors.initials: F
authors.lastname: Iqbal
authors.affiliation: Professor, Department of Cardiology, Gauhati Medical College, Guwahati, India.
authors.forename: J C
authors.initials: JC
authors.lastname: Barkataki
mesh_terms: D054058:Acute Coronary Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D017023:Coronary Angiography; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007902:Length of Stay / Q000639:trends; D008297:Male; D008875:Middle Aged; D009204:Myocardial Revascularization / Q000379:methods*; D011446:Prospective Studies; D012042:Registries; D015996:Survival Rate / Q000639:trends; D062606:Tertiary Care Centers; D015912:Thrombolytic Therapy / Q000379:methods*
keywords: Acute coronary syndrome; Clinical spectrum; North Eastern India