title: Neurological soft signs in antisocial men and relation with psychopathy.
abstract: Neurological soft signs (NSS) were studied in some axis-I disorders like schizophrenia, obsessive compulsive disorder, bipolar disorder, alcohol and substance abuse disorder. Aim of this study is detection of neurological soft signs in antisocial personality disorder and relation of these signs with psychopathy. The study was included 41 antisocial men and 41 healthy control subjects. Sociodemographic form, neurological evaluation scale and Hare psychopathy checklist was applied to the antisocial subjects, whereas sociodemographic form and neurological evaluation scale were applied to the controls. Antisocial men exhibited significiantly more NSS in total score and subgroups scales (p<0.05). It was shown that there was a significant association with psychopathy scores and NSS sequencing complex motor tasks (r=0.309; p=0.049) and NSS other tests subgroup scores (r=0.328; p=0.037). Similar relation was also observed in comparison between psychopathy subgroups. NSS accepted as being endophenotypes in schizophrenia, were also detected in antisocial group significantly more than controls in our study. Significant relationship between psychopathy and NSS may also hint the role of genetic mechanisms in personality development, though new extended studies with larger sample size are needed for clarification of this relationship.
authors.affiliation: Department of Psychiatry, Cerrahpaşa Faculty of Medicine, Istanbul University, Turkey. Electronic address: ofdmed@yahoo.com.
authors.forename: Omer Faruk
authors.initials: OF
authors.lastname: Demirel
authors.affiliation: Department of Psychiatry, Cerrahpaşa Faculty of Medicine, Istanbul University, Turkey.
authors.forename: Aysegul
authors.initials: A
authors.lastname: Demirel
authors.affiliation: Department of Child and Adolescent Psychiatry, Cerrahpaşa Faculty of Medicine, Istanbul University, Turkey.
authors.forename: Muhammed Tayyib
authors.initials: MT
authors.lastname: Kadak
authors.affiliation: Department of Psychiatry, Cerrahpaşa Faculty of Medicine, Istanbul University, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Emül
authors.affiliation: Department of Psychiatry, Cerrahpaşa Faculty of Medicine, Istanbul University, Turkey.
authors.forename: Alaattin
authors.initials: A
authors.lastname: Duran
mesh_terms: D000293:Adolescent; D000328:Adult; D000987:Antisocial Personality Disorder / Q000175:diagnosis* / Q000523:psychology; D016022:Case-Control Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D009483:Neuropsychological Tests; D011569:Psychiatric Status Rating Scales; D011618:Psychotic Disorders / Q000175:diagnosis* / Q000523:psychology; D063189:Symptom Assessment; D055815:Young Adult
keywords: Antisocial personality disorder; Neurological soft signs; Psychopathy