title: The protective effect of two commercial formats of Ginkgo biloba on motor alterations induced by cassava juice (Manihot esculenta Crantz) in Wistar rats.
abstract: BACKGROUND
  This study evaluated the protective effects of 2 commercial formats of Ginkgo biloba on motor alterations induced by cassava (Manihot esculenta Crantz) juice consumption in male Wistar rats.
  
  
  METHODS
  The effects were evaluated with the open field and swim tests at 0, 7, 14, 21, and 28 days of treatment, one hour after administering the product.
  
  
  RESULTS
  Compared to controls, open field crossings increased after day 21 of cassava juice consumption, and lateral swimming in the swim test was reported after day 7.
  
  
  CONCLUSIONS
  Ginkgo biloba extracts prevented motor alterations associated with cassava juice consumption, probably due to the flavonoid content in both formats of Ginkgo biloba.
authors.affiliation: Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, México. Electronic address: edrivadeneyra@uv.mx.
authors.forename: E
authors.initials: E
authors.lastname: Rivadeneyra-Domínguez
authors.affiliation: Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, México; Laboratorio de Biología y Química Molecular de Frutas, Instituto de Ciencias Básicas, Universidad Veracruzana, Xalapa, Veracruz, México.
authors.forename: A
authors.initials: A
authors.lastname: Vázquez-Luna
authors.affiliation: Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, México; Instituto de Neuroetología, Universidad Veracruzana, Xalapa, Veracruz, México.
authors.forename: J F
authors.initials: JF
authors.lastname: Rodríguez-Landa
authors.affiliation: Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, México.
authors.forename: C V
authors.initials: CV
authors.lastname: Mérida-Portilla
authors.affiliation: Laboratorio de Farmacotoxicología, Facultad de Química Farmacéutica Biológica, Universidad Veracruzana, Xalapa, Veracruz, México; Laboratorio de Biología y Química Molecular de Frutas, Instituto de Ciencias Básicas, Universidad Veracruzana, Xalapa, Veracruz, México.
authors.forename: R
authors.initials: R
authors.lastname: Díaz-Sobac
mesh_terms: D000818:Animals; D001522:Behavior, Animal / Q000187:drug effects; D020441:Ginkgo biloba / Q000009:adverse effects*; D008297:Male; D002365:Manihot / Q000737:chemistry / Q000187:drug effects*; D008800:Mexico; D009043:Motor Activity / Q000187:drug effects*; D009570:Nitriles; D051381:Rats; D017208:Rats, Wistar; D013550:Swimming
chemical_list: D009570:Nitriles; C005091:linamarin
keywords: Alteración motora; Cassava; Ginkgo biloba; Konzo; Lateral swim; Linamarin; Linamarina; Motor alterations; Nado lateral; Yuca