title: Seasonal Incidence of Emergent Coronary Artery Bypass Grafting Surgery.
abstract: BACKGROUND
  Emergent coronary artery bypass grafting (CABG) surgery is often required in the case of severe coronary artery disease, which is refractory to traditional management. The objective of our study was to test the hypothesis that there is seasonal variation in the incidence of emergent CABG.
  
  
  METHODS
  A sinusoidal logistic regression model was used to analyze operative data at our cardiovascular institute of 270 cases spanning 5939 calendar days.
  
  
  RESULTS
  A cyclic peak risk for emergent CABG was observed for late winter (calendar day 66; P = .036). The odds ratios for the 1-, 2- and 3-month window surrounding this peak were 1.8 (95% CI = 0.94-3.5, P = .072), 1.6 (95% CI = 1.06-2.5, P = .024) and 1.4 (95% CI = 0.9-1.8, P = .066), respectively.
  
  
  CONCLUSIONS
  Our results suggest that a seasonal variation may exist in the incidence of patients presenting with severe coronary artery disease requiring emergent CABG. This information is useful in the scheduling of hospital resources and staff. It also provides important etiology clues underlying coronary artery disease that may lead to future interventions or targeted therapies.
authors.affiliation: 1. East Carolina Heart Institute, Department of Cardiovascular Sciences, East Carolina University, Greenville, NC 2.Center for Health Disparities, Brody School of Medicine, East Carolina University, Greenville, NC 3. The College of Nursing, East Carolina University, Greenville, NC. jimmy.efird@stanfordalumni.org.
authors.forename: Jimmy T
authors.initials: JT
authors.lastname: Efird
authors.affiliation: Department of Internal Medicine, Medical University of South Carolina, Charleston, SC. wfgriffin3@gmail.com.
authors.forename: William Fenner
authors.initials: WF
authors.lastname: Griffin
authors.affiliation: Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA. jimmy.efird@stanfordalumni.org.
authors.forename: Stephen W
authors.initials: SW
authors.lastname: Davies
authors.affiliation: Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC. jimmy.efird@stanfordalumni.org.
authors.forename: Wesley T
authors.initials: WT
authors.lastname: O'Neal
authors.affiliation: The College of Nursing, East Carolina University, Greenville, NC. jimmy.efird@stanfordalumni.org.
authors.forename: Patricia B
authors.initials: PB
authors.lastname: Crane
authors.affiliation: East Carolina Heart Institute, Department of Cardiovascular Sciences, East Carolina University, Greenville, NC. jimmy.efird@stanfordalumni.org.
authors.forename: Linda C
authors.initials: LC
authors.lastname: Kindell
authors.affiliation: Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, TN. jimmy.efird@stanfordalumni.org.
authors.forename: Jason B
authors.initials: JB
authors.lastname: O'Neal
authors.affiliation: East Carolina Heart Institute, Department of Cardiovascular Sciences, East Carolina University, Greenville, NC. jimmy.efird@stanfordalumni.org.
authors.forename: W Randolph
authors.initials: WR
authors.lastname: Chitwood
authors.affiliation: East Carolina Heart Institute, Department of Cardiovascular Sciences, East Carolina University, Greenville, NC. jimmy.efird@stanfordalumni.org.
authors.forename: Alan P
authors.initials: AP
authors.lastname: Kypson
mesh_terms: D001026:Coronary Artery Bypass / Q000379:methods* / Q000706:statistics & numerical data; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000601:surgery*; D004630:Emergencies / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D008297:Male; D008875:Middle Aged; D009657:North Carolina / Q000453:epidemiology; D016017:Odds Ratio; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012424:Rural Population; D012621:Seasons