title: Amino acid-promoted C-H alkylation with alkylboronic acids using a removable directing group.
abstract: Palladium-catalyzed C-H alkylation reaction with alkylboronic acids has successfully been developed using a removable pyridyldiisopropylsilyl directing group. The amino acid played a crucial role as a ligand in the reaction. The alkylation protocol is also applicable to the coupling of C(sp(3))-H bonds with alkylboronic acids.
authors.affiliation: Department of Chemistry, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, P. R. China. zhangyanghui@tongji.edu.cn.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Chemistry, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, P. R. China. zhangyanghui@tongji.edu.cn.
authors.forename: Hang
authors.initials: H
authors.lastname: Jiang
authors.affiliation: Department of Chemistry, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, P. R. China. zhangyanghui@tongji.edu.cn.
authors.forename: Dushen
authors.initials: D
authors.lastname: Chen
authors.affiliation: Department of Chemistry, and Shanghai Key Lab of Chemical Assessment and Sustainability, Tongji University, 1239 Siping Road, Shanghai, 200092, P. R. China. zhangyanghui@tongji.edu.cn.
authors.forename: Yanghui
authors.initials: Y
authors.lastname: Zhang