title: Brain protection during cephalosomatic anastomosis.
abstract: Cephalosomatic anastomosis requires neuroprotective techniques, such as deep hypothermia, to preserve brain activity. Despite the failure of pharmacologic neuroprotection, new strategies, including ischemic pre- and postconitioning and the use of Perftoran, have to be explored to complement hypothermia. This article summarizes the field of brain protection during CSA and these promising strategies.
authors.affiliation: Hand and Microsurgical Center, the Second Affiliated Hospital of Harbin Medical University, Harbin, China; State-Province Key Laboratories of Biomedicine-Pharmaceutics, Harbin Medical University, Harbin, China; Department of Molecular Pharmacology and Therapeutics, Stritch School of Medicine, Loyola University Chicago, Chicago, IL. Electronic address: XiaoPingRenchinarenxg@126.com.
authors.forename: XiaoPing
authors.initials: X
authors.lastname: Ren
authors.affiliation: Stem Cells Technique and Nanocomposite Materials Group Leader, Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences, Moscow, Russia.
authors.forename: Elena V
authors.initials: EV
authors.lastname: Orlova
authors.affiliation: Institute of Theoretical and Experimental Biophysics Russian Academy of Sciences, Moscow, Russia.
authors.forename: Eugene I
authors.initials: EI
authors.lastname: Maevsky
authors.affiliation: Turin Advanced Neuromodulation Group, Turin, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bonicalzi
authors.affiliation: Turin Advanced Neuromodulation Group, Turin, Italy. Electronic address: sercan@inwind.it.
authors.forename: Sergio
authors.initials: S
authors.lastname: Canavero
mesh_terms: D000818:Animals; D001921:Brain / Q000098:blood supply*; D016380:Brain Tissue Transplantation / Q000379:methods*; D005466:Fluorocarbons / Q000627:therapeutic use; D006801:Humans; D007036:Hypothermia, Induced; D019194:Ischemic Preconditioning; D018696:Neuroprotective Agents / Q000627:therapeutic use
chemical_list: D005466:Fluorocarbons; D018696:Neuroprotective Agents; C063334:perftoran