title: Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease) and cirrhosis of the liver: A case report and literature review.
abstract: Patients with cirrhosis of the liver usually present with a small shrunken liver and a large spleen. The presence of an unusually huge liver should prompt the treating doctor to look for another cause, as this may be treatable and improve the patient's outcome. In South Africa tuberculosis and lymphoma in the presence of HIV infection should be excluded. Sinus histiocytosis with massive lymphadenopathy and cirrhosis is a rare combination and has not been reported before in the literature. This case is intended to make clinicians aware of this rare combination of diseases.
authors.affiliation: Gastroenterology Division of Internal Medicine, Steve Biko Academic Hospital and School of Medicine, Faculty of Health Sciences, University of Pretoria, South Africa. kgomomk@worldonline.co.za.
authors.forename: Mpho Klaas
authors.initials: MK
authors.lastname: Kgomo
authors.forename: Ali A
authors.initials: AA
authors.lastname: Elnagar
authors.forename: Christian
authors.initials: C
authors.lastname: Jeske
authors.forename: Jackoo
authors.initials: J
authors.lastname: Nagel
mesh_terms: D005260:Female; D015618:Histiocytosis, Sinus / Q000150:complications*; D006801:Humans; D008103:Liver Cirrhosis / Q000150:complications*; D000072281:Lymphadenopathy / Q000150:complications*; D008875:Middle Aged