title: Orbital lymphoma with isolated occult bilateral adrenal involvement: report of an extremely rare case.
abstract: Orbital lymphoma is very rare malignant neoplasm, usually diagnosed in early stage of disease as primary lymphoma, but dissemination occurs in approximately 33% of cases. Isolated bilateral adrenal lymphomatous involvement is extremely rare, described in 0.83% of cases. We present autopsy case of a 63-year-old man with bilateral orbital diffuse large cell lymphoma, clinical stage IEA, successfully treated by one cycle of chemo- and radiotherapy, but after administration of the second cycle, the patient developed signs of gastrointestinal hemorrhage and died two months after the diagnosis. Autopsy findings exclude lymphoma involvement of any organ except histopathological infiltration of both adrenal glands without evidence of a mass lesion.
authors.affiliation: Institute of Pathology, Faculty of Medicine, University of Belgrade, Serbia; tatjana.terzic@sbb.rs.
authors.forename: Tatjana
authors.initials: T
authors.lastname: Terzic
authors.forename: Dejan
authors.initials: D
authors.lastname: Rasic
authors.forename: Ruzica
authors.initials: R
authors.lastname: Nedeljkov-Jancic
authors.forename: Dragana
authors.initials: D
authors.lastname: Pesic
authors.forename: Snezana
authors.initials: S
authors.lastname: Lesovic
authors.forename: Vladimir
authors.initials: V
authors.lastname: Jurisic
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000150:complications* / Q000473:pathology*; D001344:Autopsy; D001706:Biopsy; D017809:Fatal Outcome; D006801:Humans; D008223:Lymphoma / Q000150:complications* / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D009918:Orbital Neoplasms / Q000150:complications* / Q000473:pathology*