title: ANEMIA IN INFLAMMATORY BOWEL DISEASE MORE THAN AN EXTRAINTESTINAL COMPLICATION.
abstract: The most common hematologic complication of inflammatory bowel disease (IBD)--ulcerative colitis and Crohn's Disease is anemia. Anemia in patients with IBD may be a result of iron, vitamin B12 or folate deficiency; anemia of chronic disease and hemolytic anemia are other causes in these patients. Factors contributing to the development of anemia include chronic gastrointestinal blood loss, vitamin B12 malabsorption secondary to terminal ileitis, folate deficiency as a result of sulfasalazine therapy. Approximately 30% of patients with IBD have hemoglobin levels below 12 g/dl. The risk of developing anemia relates to disease activity, given that blood loss and inflammatory anemia are triggered by intestinal inflammation. In the management strategy of IBD patients with anemia it is important to distinguish between the different types of anemia in order to decide an appropriate manner of treatment.
authors.forename: Roxana Maria
authors.initials: RM
authors.lastname: Nemeş
authors.forename: Corina Silvia
authors.initials: CS
authors.lastname: Pop
authors.forename: Dorina
authors.initials: D
authors.lastname: Calagiu
authors.forename: Denisa
authors.initials: D
authors.lastname: Dobrin
authors.forename: Diana
authors.initials: D
authors.lastname: Chetroiu
authors.forename: Petruta
authors.initials: P
authors.lastname: Jantea
authors.forename: Paraschiva
authors.initials: P
authors.lastname: Postolache
mesh_terms: D000740:Anemia / Q000097:blood / Q000175:diagnosis / Q000209:etiology*; D018798:Anemia, Iron-Deficiency / Q000209:etiology; D015415:Biomarkers / Q000097:blood; D003093:Colitis, Ulcerative / Q000150:complications; D003424:Crohn Disease / Q000150:complications; D005492:Folic Acid / Q000097:blood*; D006454:Hemoglobins / Q000032:analysis; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000150:complications*; D007501:Iron / Q000097:blood*; D000090463:Iron Deficiencies; D012307:Risk Factors; D014806:Vitamin B 12 Deficiency / Q000209:etiology
chemical_list: D015415:Biomarkers; D006454:Hemoglobins; D005492:Folic Acid; D007501:Iron