title: New expectations in the treatment of anemia in chronic kidney disease.
abstract: The new drugs developed for the treatment of anemia in chronic kidney disease patients, together with their mechanisms of action are reviewed. At present, many of them are already in advanced stages of clinical trials and is expected to be incorporated into the therapeutic arsenal in the coming years. The potential benefits and possible limitations are also described.
authors.affiliation: Servicio de Nefrología, Hospital Universitario Gregorio Marañón, Madrid, España. Electronic address: juanmlopez@senefro.org.
authors.forename: Juan M
authors.initials: JM
authors.lastname: López-Gómez
authors.affiliation: Servicio de Nefrología, Hospital Universitario Gregorio Marañón, Madrid, España.
authors.forename: Soraya
authors.initials: S
authors.lastname: Abad
authors.affiliation: Servicio de Nefrología, Hospital Universitario Gregorio Marañón, Madrid, España.
authors.forename: Almudena
authors.initials: A
authors.lastname: Vega
mesh_terms: D028341:Activins / Q000037:antagonists & inhibitors; D000740:Anemia / Q000188:drug therapy* / Q000209:etiology; D051792:Basic Helix-Loop-Helix Proteins / Q000502:physiology; D002986:Clinical Trials as Topic; D015507:Drugs, Investigational / Q000627:therapeutic use; D004920:Erythropoiesis / Q000187:drug effects; D004921:Erythropoietin / Q000502:physiology; D050980:GATA Transcription Factors / Q000037:antagonists & inhibitors / Q000502:physiology; D006397:Hematinics / Q000145:classification / Q000494:pharmacology / Q000627:therapeutic use*; D064451:Hepcidins / Q000037:antagonists & inhibitors; D006801:Humans; D015337:Multicenter Studies as Topic; D064800:Prolyl-Hydroxylase Inhibitors / Q000494:pharmacology / Q000627:therapeutic use; D016032:Randomized Controlled Trials as Topic; D017467:Receptors, Erythropoietin / Q000819:agonists; D006435:Renal Dialysis / Q000009:adverse effects; D051436:Renal Insufficiency, Chronic / Q000097:blood / Q000150:complications* / Q000628:therapy; D000099162:Endothelial PAS Domain-Containing Protein 1
chemical_list: D028341:Activins; D051792:Basic Helix-Loop-Helix Proteins; D015507:Drugs, Investigational; D004921:Erythropoietin; D050980:GATA Transcription Factors; D006397:Hematinics; D064451:Hepcidins; D064800:Prolyl-Hydroxylase Inhibitors; D017467:Receptors, Erythropoietin; D000099162:Endothelial PAS Domain-Containing Protein 1; C554270:EPO protein, human; C578702:HAMP protein, human
keywords: Anemia; Chronic kidney disease; Enfermedad renal crónica; Hepcidin; Hepcidina; Inhibidores de prolil-hidroxilasa; Prolyl-hidroxilase inhibitors; Sotatercept