title: Beyond testosterone cypionate: evidence behind the use of nandrolone in male health and wellness.
abstract: Characterized by low serum testosterone levels and diverse symptoms, male hypogonadism is a common condition. Current medical treatment focuses on testosterone supplementation using multiple modalities such as injections, gels and pellets. Interestingly, while testosterone is considered an anabolic androgenic steroid, it has not been saddled with the social stigma that other, similar medications have. The goal of this review is to highlight an anabolic steroid, 19-nortestosterone (i.e., nandrolone, deca-durabolin) and illustrate prospective therapeutic applications for male health. Containing a chemical structure similar to testosterone, nandrolone has a higher myotrophic: androgenic ratio resulting in improved effects on muscle mass. Animal models have suggested application in the improvement of joint healing following rotator cuff repair. Minimal literature exists regarding the use of nandrolone and, as such, further human studies are required.
authors.affiliation: 1 Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA ; 2 Men's Health Center, Urology of Indiana, Indianapolis, Indiana 46260, USA.
authors.forename: Michael M
authors.initials: MM
authors.lastname: Pan
authors.affiliation: 1 Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA ; 2 Men's Health Center, Urology of Indiana, Indianapolis, Indiana 46260, USA.
authors.forename: Jason R
authors.initials: JR
authors.lastname: Kovac
keywords: Nandrolone; alopecia; erectile dysfunction (ED); joint healing; muscle growth; pharmacology; testosterone supplementation therapy (TST)