title: Annexin-Mediated Calcium Signalling in Plants.
abstract: Calcium-permeable channels underpin elevations of free calcium that encode specific signals in stress adaptation, development and immunity. Identifying the genes encoding these channels remains a central goal of plant signalling research. Evidence now suggests that members of the plant annexin family function as unconventional calcium-permeable channels, with roles in development and stress signalling. Arabidopsis annexin 1 mediates a plasma membrane calcium-permeable conductance in roots that is activated by reactive oxygen species. Recombinant annexin 1 forms a very similar conductance in planar lipid bilayers, indicating that this protein could facilitate the in vivo conductance directly. The annexin 1 mutant is impaired in salinity-induced calcium signalling. Protein-protein interactions, post-translational modification and dynamic association with membranes could all influence annexin-mediated calcium signalling and are reviewed here. The prospect of annexins playing roles in calcium signalling events in symbiosis and immunity are considered.
authors.affiliation: Department of Plant Sciences, University of Cambridge, Cambridge CB2 3EA, UK. jmd32@cam.ac.uk.
authors.forename: Julia M
authors.initials: JM
authors.lastname: Davies
keywords: Arabidopsis; Medicago; annexin; calcium; channel; signal; stress