title: Differences in Urodynamic Parameters Between Women With Interstitial Cystitis and/or Bladder Pain Syndrome and Severe Overactive Bladder.
abstract: OBJECTIVE
  To identify differences in urodynamic parameters between female outpatients with interstitial cystitis (IC) and/or bladder pain syndrome (BPS) and severe overactive bladder (OAB).
  
  
  METHODS
  This cross-sectional study included 24 and 28 consecutive IC/BPS and severe OAB female patients, respectively. IC/BPS was defined based on the American Urological Association guideline, and severe OAB was defined based on baseline symptoms recorded in a voiding diary. Before treatment, symptom assessment using questionnaires and a 3-day voiding diary, as well as laboratory tests, were performed at the initial visit. The patients' baseline characteristics and urodynamic parameters were compared between the IC/BPS and severe OAB groups.
  
  
  RESULTS
  The IC/BPS group showed fewer episodes of urge incontinence and shorter duration of symptoms than the severe OAB group (P = .019, P = .017, respectively). Volumes at first sense, normal desire, strong desire, and maximal capacity during filling cystometry (MBC) were significantly higher in the severe OAB group than in the IC/BPS group (P <.001, P <.001, P = .006, P <.001, respectively). The IC/BPS and severe OAB groups showed significant differences in urodynamic parameters in terms of MBC and the volume discrepancy between MBC and maximal voided volume (P <.001, both). The receiver operating characteristic curve also showed an area under the curve of 0.760 and 0.783 for MBC and volume discrepancy, respectively (both P <.001).
  
  
  CONCLUSIONS
  Data from our study suggest that combined with other clinical findings, urodynamic studies could provide useful information to differentiate between a diagnosis of IC/BPS or severe OAB.
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Ji Sung
authors.initials: JS
authors.lastname: Shim
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Sung Gu
authors.initials: SG
authors.lastname: Kang
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Jae Young
authors.initials: JY
authors.lastname: Park
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Jae Hyun
authors.initials: JH
authors.lastname: Bae
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Seok Ho
authors.initials: SH
authors.lastname: Kang
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Hong Seok
authors.initials: HS
authors.lastname: Park
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Du Geon
authors.initials: du G
authors.lastname: Moon
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Jun
authors.initials: J
authors.lastname: Cheon
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Jeong Gu
authors.initials: JG
authors.lastname: Lee
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea.
authors.forename: Je Jong
authors.initials: JJ
authors.lastname: Kim
authors.affiliation: Department of Urology, Korea University Medical Center, Seoul, Republic of Korea. Electronic address: mamah@daum.net.
authors.forename: Mi Mi
authors.initials: MM
authors.lastname: Oh
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D018856:Cystitis, Interstitial / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012189:Retrospective Studies; D012720:Severity of Illness Index; D053201:Urinary Bladder, Overactive / Q000503:physiopathology*; D014563:Urodynamics