title: Management of orbital invasion in sinonasal malignancies.
abstract: Indications for preservation of orbital contents in case of malignant sinonasal tumors invading the orbit remain controversial.
  
  
  
  A retrospective consecutive review was conducted of patients in a tertiary care center over a 15-year period.
  
  
  
  Ninety-three patients were diagnosed with a malignant tumor invading the orbit. Eighty-three were treated with curative intent of which 58 underwent surgery. Mean follow-up was 45 months. Orbital preservation was feasible in 66% of cases, whereas orbital clearance was performed in cases of locally advanced disease (invasion of extraocular muscles, ocular globe, or orbital apex). Local control rate was 70% for patients treated with orbital clearance and 74% for those with orbital preservation, with no statistical difference. Five-year survival and 5-year relapse-free survival were similar in both groups.
  
  
  
  Using our strategy, the eye can be spared in more patients than what is currently proposed, without oncologic or survival disadvantages. © 2016 Wiley Periodicals, Inc. Head Neck 38: 1708-1716, 2016.
authors.affiliation: Department of Head and Neck Surgery, Gustave Roussy Cancer Institute, Villejuif Cedex, France. quentin_lisan@yahoo.fr.
authors.forename: Quentin
authors.initials: Q
authors.lastname: Lisan
authors.affiliation: Department of Head and Neck Surgery, Gustave Roussy Cancer Institute, Villejuif Cedex, France.
authors.forename: Frédéric
authors.initials: F
authors.lastname: Kolb
authors.affiliation: Department of Head and Neck Surgery, Gustave Roussy Cancer Institute, Villejuif Cedex, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Temam
authors.affiliation: Department of Radiation Oncology, Gustave Roussy Cancer Institute, Villejuif Cedex, France.
authors.forename: Yungan
authors.initials: Y
authors.lastname: Tao
authors.affiliation: Department of Head and Neck Surgery, Gustave Roussy Cancer Institute, Villejuif Cedex, France.
authors.forename: François
authors.initials: F
authors.lastname: Janot
authors.affiliation: Department of Head and Neck Surgery, Gustave Roussy Cancer Institute, Villejuif Cedex, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Moya-Plana
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D008875:Middle Aged; D009361:Neoplasm Invasiveness; D009362:Neoplasm Metastasis; D009364:Neoplasm Recurrence, Local; D009918:Orbital Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D010255:Paranasal Sinus Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery / Q000628:therapy; D012189:Retrospective Studies; D016019:Survival Analysis
keywords: orbital clearance; orbital invasion; orbital preservation; sinonasal malignancy; transfacial approach