title: Antimicrobial and mechanical properties of dental resin composite containing bioactive glass.
abstract: BACKGROUND
  The aim of this study was to evaluate the antimicrobial efficacy and mechanical properties of dental resin composites containing different amounts of microparticulate bioactive glass (BAG).
  
  
  METHODS
  Experimental resin composites were prepared by mixing resin matrix (70% BisGMA and 30% TEGDMA) and inorganic filler with various fractions of BAG to achieve final BAG concentrations of 5, 10 and 30 wt%. Antimicrobial efficacy was assessed in aqueous suspension against Escherichia coli, Staphylococcus aureus and Streptococcus mutans and in biofilm against S. mutans. The effect of incorporation of BAG on the mechanical properties of resin composite was evaluated by measuring the surface roughness, compressive strength and flexural strength.
  
  
  RESULTS
  Under the dynamic contact condition, viable counts of E. coli, S. aureus and S. mutans in suspensions were reduced up to 78%, 57% and 50%, respectively, after 90 minutes of exposure to disc-shaped composite specimens, depending on the BAG contents. In 2-day-old S. mutans biofilm, incorporation of BAG into composite at ratios of 10% and 30% resulted in 0.8 and 1.4 log reductions in the viable cell counts compared with the BAG-free composite, respectively. The surface roughness values of composite specimens did not show any significant difference (p&gt;0.05) at any concentration of BAG. However, compressive and flexural strengths of composite were decreased significantly with addition of 30% BAG (p&lt;0.05).
  
  
  CONCLUSIONS
  The results demonstrated the successful utilization of BAG as a promising biomaterial in resin composites to provide antimicrobial function.
authors.affiliation: Department of Pediatric Dentistry, Necmettin Erbakan University, Konya - Turkey.
authors.forename: Emre
authors.initials: E
authors.lastname: Korkut
authors.affiliation: Department of Molecular Biology and Genetics, Necmettin Erbakan University, Konya - Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Torlak
authors.affiliation: Department of Pediatric Dentistry, Selçuk University, Konya - Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Altunsoy
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D000890:Anti-Infective Agents / Q000737:chemistry*; D003188:Composite Resins / Q000737:chemistry*; D004926:Escherichia coli / Q000254:growth & development*; D005898:Glass / Q000737:chemistry*; D011140:Polyurethanes / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000254:growth & development*; D013295:Streptococcus mutans / Q000254:growth & development*
chemical_list: D000180:Acrylic Resins; D000890:Anti-Infective Agents; C029012:Composite Dental Resin; D003188:Composite Resins; D011140:Polyurethanes