title: Roles of Circular RNAs in Neurologic Disease.
abstract: Circular RNAs (circRNAs) are a novel type of endogenous noncoding RNA receiving increasing attention. They have been shown to act as a natural microRNA sponges that repress the activity of corresponding miRNAs by binding with them, thus regulating target genes. Numerous studies have shown that miRNAs are involved in the pathogenesis of neurological diseases. Therefore, circRNAs may act as important regulatory factors in the occurrence and development processes of neurological disease.
authors.affiliation: Department of Neurology, Jinshan Hospital, Fudan UniversityShanghai, China; Department of Neurology, Shanghai Medical College, Fudan UniversityShanghai, China.
authors.forename: Yiye
authors.initials: Y
authors.lastname: Shao
authors.affiliation: Department of Neurology, Jinshan Hospital, Fudan UniversityShanghai, China; Department of Neurology, Shanghai Medical College, Fudan UniversityShanghai, China.
authors.forename: Yinghui
authors.initials: Y
authors.lastname: Chen
keywords: circular RNA; microRNA; neurological disease; non-coding RNA; pathogenesis