title: Fulminant liver failure in a neonate.
abstract: Neonatal acute liver disease is relatively rare, with multiple different aetiologies including congenital infections, metabolic disorders, gestational alloimmune liver disease, haemophagocytic lymphohistiocytosis, and ischaemic injury. We report a case of neonatal liver failure in a preterm, growth-restricted infant, who underwent extensive investigation and was clinically diagnosed with gestational alloimmune liver disease, which was confirmed on post-mortem examination. We then discuss management of neonatal liver failure and gestational alloimmune liver disease, including maternal management in future pregnancies.
authors.affiliation: Department of Neonatal Services, Royal Women's Hospital, Melbourne, Victoria, Australia.
authors.forename: Naomi E
authors.initials: NE
authors.lastname: Clarke
authors.affiliation: Department of Neonatal Services, Royal Women's Hospital, Melbourne, Victoria, Australia.
authors.forename: Damien
authors.initials: D
authors.lastname: Gilby
authors.affiliation: Department of Clinical Haematology, Royal Women's Hospital, Melbourne, Victoria, Australia.
authors.forename: Helen
authors.initials: H
authors.lastname: Savoia
authors.affiliation: Department of Gastroenterology, Royal Women's Hospital, Melbourne, Victoria, Australia.|Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.|Murdoch Women's Research Institute, Melbourne, Victoria, Australia.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Oliver
authors.affiliation: Department of Neonatal Services, Royal Women's Hospital, Melbourne, Victoria, Australia.
authors.forename: Sheryle
authors.initials: S
authors.lastname: Rogerson