title: Waist-hip ratio and 1-year clinical outcome in patients with non-ST-elevation myocardial infarctions.
abstract: OBJECTIVE
  Obesity is a well-known cardiovascular disease risk factor. We evaluated the relationship between the waist-hip ratio (WHR), as a surrogate marker of central obesity, and clinical outcomes in patients with non-ST-segment elevation myocardial infarctions (NSTEMIs) undergoing percutaneous coronary interventions (PCIs).
  
  
  METHODS
  Between 2008 and 2010, NSTEMI patients who underwent PCI and who had available anthropometric data were divided into three groups according to their WHR tertile range. Clinical outcomes in the groups were analyzed.
  
  
  RESULTS
  Increasing incidences of hypertension and diabetes mellitus were associated with increasing WHR. As the WHR increased, a disintegration of patient metabolic patterns was documented in laboratory findings. There was no difference in the 1-year mortality rates between the three groups. However, increasing 1-year major adverse cardiovascular event rates were documented as the WHR increased (13, 14.7, and 19.4% in tertile groups 1-3, respectively; P=0.005). After adjusting for confounding variables, the highest tertile group was associated with increased 1-year mortality and major adverse cardiovascular event rates compared with the lowest tertile group. These differences arose from the female subgroup, suggesting that the magnitude of the central obesity effect might be greater in female than in male patients.
  
  
  CONCLUSIONS
  Central obesity, represented by WHR, was associated with poor clinical outcomes in NSTEMI patients undergoing PCI, particularly among women.
authors.affiliation: aDepartment of Cardiology bMedical Research Institute, Pusan National University Hospital, Busan, South Korea.
authors.forename: Hye Won
authors.initials: HW
authors.lastname: Lee
authors.forename: Taek Jong
authors.initials: TJ
authors.lastname: Hong
authors.forename: Ju Young
authors.initials: JY
authors.lastname: Hong
authors.forename: Jong Hyun
authors.initials: JH
authors.lastname: Choi
authors.forename: Bo Won
authors.initials: BW
authors.lastname: Kim
authors.forename: Jinhee
authors.initials: J
authors.lastname: Ahn
authors.forename: Jin Sup
authors.initials: JS
authors.lastname: Park
authors.forename: Jun-Hyok
authors.initials: JH
authors.lastname: Oh
authors.forename: Jung Hyun
authors.initials: JH
authors.lastname: Choi
authors.forename: Han Cheol
authors.initials: HC
authors.lastname: Lee
authors.forename: Kwang Soo
authors.initials: KS
authors.lastname: Cha
mesh_terms: D000368:Aged; D015992:Body Mass Index; D015897:Comorbidity; D017023:Coronary Angiography; D003920:Diabetes Mellitus / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D000072658:Non-ST Elevated Myocardial Infarction / Q000175:diagnosis / Q000401:mortality / Q000628:therapy*; D056128:Obesity, Abdominal / Q000175:diagnosis* / Q000401:mortality; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects / Q000401:mortality; D012042:Registries; D056910:Republic of Korea / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D013997:Time Factors; D016896:Treatment Outcome; D049629:Waist-Hip Ratio