title: Intra-arterial Ultra-low-Dose CT Angiography of Lower Extremity in Diabetic Patients.
abstract: OBJECTIVE
  To image lower extremity arteries by CT angiography using a very low-dose intra-arterial contrast medium in patients with high risk of developing contrast-induced nephropathy (CIN).
  
  
  METHODS
  Three cases with long-standing diabetes mellitus and signs of lower extremity atherosclerotic disease were evaluated by CT angiography using 0.1 ml/kg of the body weight of contrast medium given via 10-cm-long 4F introducer by puncturing the CFA. Images were evaluated by an interventional radiologist and a cardiovascular surgeon. Density values of the lower extremity arteries were also calculated. Findings in two cases were compared with digital subtraction angiography images performed for percutaneous revascularization. Blood creatinine levels were followed for possible CIN.
  
  
  RESULTS
  Intra-arterial CT angiography images were considered diagnostic in all patients and optimal in one patient. No patient developed CIN after intra-arterial CT angiography, while one patient developed CIN after percutaneous intervention.
  
  
  CONCLUSIONS
  Intra-arterial CT angiography of lower extremity might be performed in selected patients with high risk of developing CIN. Our limited experience suggests that as low as of 0.1 ml/kg of the body weight of contrast medium may result in adequate diagnostic imaging.
authors.affiliation: Department of Radiology, Yeditepe University Hospital, İçerenköy mahallesi, Hastane yolu sokak, No: 102-104, 34752, Ataşehir, İstanbul, Turkey. draliozgen@hotmail.com.
authors.forename: Ali
authors.initials: A
authors.lastname: Özgen
authors.affiliation: Department of Cardiovascular Surgery, Yeditepe University Hospital, İçerenköy mahallesi, Hastane yolu sokak, No: 102-104, 34752, Ataşehir, İstanbul, Turkey.
authors.forename: Soner
authors.initials: S
authors.lastname: Sanioğlu
authors.affiliation: Department of Plastic Surgery, Yeditepe University Hospital, İçerenköy mahallesi, Hastane yolu sokak, No: 102-104, 34752, Ataşehir, İstanbul, Turkey.
authors.forename: Uğur Anıl
authors.initials: UA
authors.lastname: Bingöl
mesh_terms: D000368:Aged; D015901:Angiography, Digital Subtraction; D000072226:Computed Tomography Angiography / Q000379:methods*; D003287:Contrast Media; D048909:Diabetes Complications / Q000000981:diagnostic imaging*; D003920:Diabetes Mellitus; D005260:Female; D006801:Humans; D035002:Lower Extremity / Q000098:blood supply* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D058729:Peripheral Arterial Disease / Q000150:complications / Q000000981:diagnostic imaging*; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement
chemical_list: D003287:Contrast Media
keywords: CT/CTA; Contrast agents; Diabetes mellitus; Endovascular; Femoropopliteal; Limb ischemia; Peripheral artery disease