title: Prevalence, recovery patterns and predictors of quality of life and costs after non-fatal injury: the Brabant Injury Outcome Surveillance (BIOS) study.
abstract: Trauma is a major public health problem worldwide that leads to high medical and societal costs. Overall, improved understanding of the full spectrum of the societal impact and burden of injury is needed. The main purpose of the Brabant Injury Outcome Surveillance (BIOS) study is to provide insight into prevalence, predictors and recovery patterns of short-term and long-term health-related quality of life (HRQoL) and costs after injury.
  
  
  
  This is a prospective, observational, follow-up cohort study in which HRQoL, psychological, social and functional outcome, and costs after trauma will be assessed during 24 months follow-up within injured patients admitted in 1 of 10 hospitals in the county Noord-Brabant, the Netherlands. Data will be collected by self-reported questionnaires at 1 week (including preinjury assessment), and 1, 3, 6, 12 and 24 months after injury. If patients are not capable of filling out the questionnaires, proxies will be asked to participate. Also, information about mechanism and severity of injury, comorbidity and indirect and direct costs will be collected. Mixed models will be used to examine the course of HRQoL, functional and psychological outcome, costs over time and between different groups, and to identify predictors for poor or good outcome.
  
  
  
  This study should make a substantial contribution to the international collaborative effort to assess the societal impact and burden of injuries more accurately. The BIOS results will also be used to develop an outcome prediction model for outcome evaluation including, besides the classic fatal, non-fatal outcome.
  
  
  
  NCT02508675.
authors.affiliation: Department Trauma TopCare, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.|Network Emergency Care Brabant, Brabant Trauma Registry, The Netherlands.
authors.forename: M A C
authors.initials: MA
authors.lastname: de Jongh
authors.affiliation: Department Trauma TopCare, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
authors.forename: N
authors.initials: N
authors.lastname: Kruithof
authors.affiliation: Department Trauma TopCare, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.|Department of Orthopaedics, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
authors.forename: T
authors.initials: T
authors.lastname: Gosens
authors.affiliation: Department Trauma TopCare, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
authors.forename: C L P
authors.initials: CL
authors.lastname: van de Ree
authors.affiliation: Department Trauma TopCare, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
authors.forename: L
authors.initials: L
authors.lastname: de Munter
authors.affiliation: Network Emergency Care Brabant, Brabant Trauma Registry, The Netherlands.
authors.forename: L
authors.initials: L
authors.lastname: Brouwers
authors.affiliation: Department of Public Health, Erasmus MC, Rotterdam, The Netherlands.
authors.forename: S
authors.initials: S
authors.lastname: Polinder
authors.affiliation: Department Trauma TopCare, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.|Network Emergency Care Brabant, Brabant Trauma Registry, The Netherlands.|Department of Surgery, Elisabeth-TweeSteden Hospital, Tilburg, The Netherlands.
authors.forename: K W W
authors.initials: KW
authors.lastname: Lansink
mesh_terms: D017281:Cost of Illness; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D008297:Male; D009426:Netherlands / Q000453:epidemiology; D011159:Population Surveillance; D015995:Prevalence; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology*; D020127:Recovery of Function; D011795:Surveys and Questionnaires; D014947:Wounds and Injuries / Q000191:economics / Q000453:epidemiology* / Q000503:physiopathology / Q000523:psychology
keywords: Outcome of Injury