title: Impact of night-shift work on the prevalence of erosive esophagitis in shipyard male workers.
abstract: OBJECTIVE
  Whether night-shift work is a risk factor for gastroesophageal reflux disease is controversial. The aim of this study was to investigate the association between night-shift work and other factors, and erosive esophagitis.
  
  
  METHODS
  A cross-sectional study with 6040 male shipyard workers was performed. Esophagogastroduodenoscopic examination and a survey about night-shift work status, lifestyle, medical history, educational status, and marital status were conducted in all workers. The odds ratios of erosive esophagitis according to night-shift work status were calculated by using the logistic regression model.
  
  
  RESULTS
  The prevalence of erosive esophagitis increased in the night-shift workers [odds ratio, 95 % confidence interval: 1.41 (1.03-1.94)]. According to multiple logistic regression models, night-shift work, obesity, smoking, and alcohol consumption of ≥140 g/week were significant risk factors for erosive esophagitis. By contrast, Helicobacter pylori infection was negatively associated with erosive esophagitis.
  
  
  CONCLUSIONS
  Night-shift work is suggested to be a risk factor for erosive esophagitis. Avoidance of night-shift work and lifestyle modification should be considered for prevention and management of gastroesophageal reflux disease.
authors.affiliation: Department of Family Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, 877 Bangeojinsunwhando-Ro, Dong-Gu, Ulsan, 44033, Korea.
authors.forename: Tae Heum
authors.initials: TH
authors.lastname: Chung
authors.affiliation: Department of Occupational and Environmental Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, 877 Bangeojinsunwhando-Ro, Dong-Gu, Ulsan, 44033, Korea. oemdoc@naver.com.
authors.forename: Jiho
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Family Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, 877 Bangeojinsunwhando-Ro, Dong-Gu, Ulsan, 44033, Korea.
authors.forename: Moon Chan
authors.initials: MC
authors.lastname: Kim
mesh_terms: D000328:Adult; D021081:Chronobiology Disorders / Q000150:complications*; D003430:Cross-Sectional Studies; D004941:Esophagitis / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D016015:Logistic Models; D008297:Male; D066192:Manufacturing Industry; D008875:Middle Aged; D009784:Occupational Diseases / Q000453:epidemiology* / Q000209:etiology*; D016017:Odds Ratio; D015995:Prevalence; D012307:Risk Factors; D012767:Ships; D014940:Work Schedule Tolerance / Q000502:physiology
keywords: Erosive esophagitis; Male workers; Night-shift work; Prevalence