title: [THE CHANGE IN THE CONCENTRATION OF VITAMINS AFTER BARIATRIC SURGERY].
abstract: OBJECTIVE
  to study the concentration of vitamins in obese patients after bariatric surgery (BS).
  
  
  METHODS
  A total of 100 obese patients aged 19 to 61 years (78 women, 22 men). 20 patients (mean body mass index (BMI)--41.3 ± 8.2 kg/m²) had adjustable gastric banding (AGB), 40 patients--sleeve gastrectomy (SG) and 40--gastric bypass (GB) (mean BMI Group 41.1 ± 17.8 kg/m², and 45.9 ± 6.2 kg/m², respectively). The control group consisted of 10 healthy subjects (BMI--24.9 ± 3.2 kg/m²). We determined the serum level of vitamins B₁, B₂, B₅, B₆, B₉, B₁₂, C, D, niacin, biotin, and retinol-binding protein (RBP) before surgery and 1 year after it.
  
  
  RESULTS
  There was a significant reduction ofvitamins C, B₆, B₅, D and RBP both before and after BS. More than half of patients after SG, also had initial reduction of niacin. A year after BS (AGB, SG, GB) the number of patients with deficiency of these vitamins remained the same or increased. Most patients with normal or even elevated levels ofvitamin B₂, niacin and folic acid, has been declining a year after BO. The concentration of the rest of the vitamins also significantly decreased a year after all operations, but their performance remained within normal limits.
  
  
  CONCLUSIONS
  Levels of vitamins C, B₆ and D were reduced in more than 70% patients with obesity. The number of patients with low levels of vitamin C D, B₆, B₅, niacin, folic acid and RBP increased after BS. BS does not have a significant effect on the metabolism ofvitamins B₁, B₂, B₁₂ and biotin.
authors.forename: N A
authors.initials: NA
authors.lastname: Bodunova
authors.forename: E A
authors.initials: EA
authors.lastname: Sabelnikova
authors.forename: A I
authors.initials: AI
authors.lastname: Parfenov
authors.forename: R G
authors.initials: RG
authors.lastname: Askerhanov
authors.forename: E V
authors.initials: EV
authors.lastname: Tkachenko
authors.forename: G G
authors.initials: GG
authors.lastname: Varvanina
authors.forename: I U
authors.initials: IU
authors.lastname: Feydorov
authors.forename: I E
authors.initials: IE
authors.lastname: Khatkov
authors.forename: S V
authors.initials: SV
authors.lastname: Mosin
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008286:Malabsorption Syndromes / Q000097:blood* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D014815:Vitamins / Q000097:blood*; D055815:Young Adult
chemical_list: D014815:Vitamins