title: Analysis of correlation factors and pregnancy outcomes of hypertensive disorders of pregnancy - a secondary analysis of a random sampling in Beijing, China.
abstract: OBJECTIVE
  We aimed to assess the prevalence and risk factors for hypertensive disorders and to study the main pregnancy outcomes in the Beijing area of China.
  
  
  METHODS
  This study randomly sampled 15 hospitals in Beijing from Jun 2013 to Nov 2013 and evaluated 15 194 deliveries. Logistic regression analysis was used to study the association between risk factors and hypertensive disorders. Pregnancy outcomes included preterm birth, cesarean delivery and small for gestational age (SGA).
  
  
  RESULTS
  The prevalence of hypertensive disorders, preeclampsia (PE) and severe PE was 4.4, 2.7 and 1.8%, respectively. The risk factors for hypertensive disorders and severe PE were maternal body mass index before pregnancy, gestational weight gain (GWG), gestational diabetes and pre-gestational diabetes, and third trimester cholesterol (CHOL) levels. First trimester high-density lipoprotein was a protective factor for severe PE. The incidence of hypertensive disorders increased with maternal age. Preterm delivery, cesarean delivery and small infant size for gestational age were more prevalent in the severe PE group compared with the non-hypertensive group.
  
  
  CONCLUSIONS
  In the Beijing area of China, maternal body mass index before pregnancy, GWG, maternal complications of gestational diabetes and pre-gestational diabetes, and third trimester CHOL levels are risk factors for both hypertensive disorders of pregnancy and severe PE. First trimester high-density lipoprotein is a protective factor for severe PE. Severe preeclampsia leads to a higher incidence of preterm delivery, cesarean delivery and SGA infants.
authors.affiliation: a Department of Obstetrics and Gynecology , Peking University First Hospital , Beijing , PR China.
authors.forename: Yu-Chun
authors.initials: YC
authors.lastname: Zhu
authors.affiliation: a Department of Obstetrics and Gynecology , Peking University First Hospital , Beijing , PR China.
authors.forename: Hui-Xia
authors.initials: HX
authors.lastname: Yang
authors.affiliation: a Department of Obstetrics and Gynecology , Peking University First Hospital , Beijing , PR China.
authors.forename: Yu-Mei
authors.initials: YM
authors.lastname: Wei
authors.affiliation: a Department of Obstetrics and Gynecology , Peking University First Hospital , Beijing , PR China.
authors.forename: Wei-Wei
authors.initials: WW
authors.lastname: Zhu
authors.affiliation: b Tongzhou Maternal and Child Health Hospital of Beijing , Beijing , PR China.
authors.forename: Wen-Ying
authors.initials: WY
authors.lastname: Meng
authors.affiliation: c Department of Obstetrics and Gynecology , Peking University Third Hospital , Beijing , PR China.
authors.forename: Yong-Qing
authors.initials: YQ
authors.lastname: Wang
authors.affiliation: d Department of Obstetrics and Gynecology , General Hospital of Beijing Military Region , Beijing , PR China.
authors.forename: Li-Xin
authors.initials: LX
authors.lastname: Shang
authors.affiliation: e Center Hospital of Aviation Industry , Beijing , PR China.
authors.forename: Zhen-Yu
authors.initials: ZY
authors.lastname: Cai
authors.affiliation: f Pinggu Maternal and Child Health Hospital of Beijing , Beijing , PR China.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Ji
authors.affiliation: g Beijing Hospital of Miyun City , Beijing , PR China.
authors.forename: Yun-Feng
authors.initials: YF
authors.lastname: Wang
authors.affiliation: h Navy General Hospital , Beijing , PR China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Sun
authors.affiliation: i Beijing Daxing District Hongxing Hospital , Beijing , PR China.
authors.forename: Jia-Xiu
authors.initials: JX
authors.lastname: Liu
authors.affiliation: j Beijing Chui Yang Liu Hospital , Beijing , PR China.
authors.forename: Li
authors.initials: L
authors.lastname: Wei
authors.affiliation: k Peking University Shougang Hospital , Beijing , PR China.
authors.forename: Yu-Feng
authors.initials: YF
authors.lastname: Sun
authors.affiliation: l Combined with Traditional Chinese and Western Medicine Hospital of Beijing City , Beijing , PR China.
authors.forename: Xue-Ying
authors.initials: XY
authors.lastname: Zhang
authors.affiliation: m Beijing No.6 Hospital , Beijing , PR China.
authors.forename: Tian-Xia
authors.initials: TX
authors.lastname: Luo
authors.affiliation: n Beijing Changping Hospital of Traditional Chinese Medicine , Beijing , PR China , and.
authors.forename: Hai-Xia
authors.initials: HX
authors.lastname: Chen
authors.affiliation: o General Hospital of Jingmei Group , Beijing , PR China.
authors.forename: Li-Jun
authors.initials: LJ
authors.lastname: Yu
mesh_terms: D000328:Adult; D000068476:Beijing / Q000453:epidemiology; D002585:Cesarean Section / Q000706:statistics & numerical data*; D016009:Chi-Square Distribution; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced / Q000453:epidemiology*; D015994:Incidence; D007231:Infant, Newborn; D007236:Infant, Small for Gestational Age; D016015:Logistic Models; D016017:Odds Ratio; D011247:Pregnancy; D011256:Pregnancy Outcome / Q000453:epidemiology*; D047928:Premature Birth / Q000453:epidemiology*; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Hypertension; incidence; outcome; preeclampsia; risk factor