title: Openness to experience shortens duration of untreated psychosis in Serbian clinical population.
abstract: To determine duration of untreated psychosis (DUP) in patients with schizophrenia-spectrum disorders from Serbia and to analyse factors that potentially contribute to the treatment delay, with focus on personality traits.
  
  
  
  Fifty seven patients (males 54.4%; age = 29.9 ± 6.0 yrs; age at the illness onset = 24.9 ± 5.1 yrs; IQ = 93.5 ± 12.2) were included. The assessment consisted of Nottingham Onset Schedule (NOS), Premorbid Adjustment Scale (PAS) and NEO Personality Inventory (NEO-PI-R). We used Cox regression model to evaluate relationship between DUP and explanatory variables.
  
  
  
  Based on the most restrictive definition, the length of DUP in our sample was 77.8 ± 120.6 weeks (MED = 25.0 weeks). DUP was negatively associated with openness to experience (B = -0.804, P = 0.024).
  
  
  
  We report the first evidence of DUP in Serbia, emphasizing that the personality domains are likely to impact the use of mental health care in persons with psychosis.
authors.affiliation: School of Medicine, University of Belgrade, Belgrade, Serbia.|Clinic for Psychiatry, Clinical Centre of Serbia, Belgrade, Serbia.
authors.forename: Nadja P
authors.initials: NP
authors.lastname: Maric
authors.affiliation: Clinic for Psychiatry, Clinical Centre of Serbia, Belgrade, Serbia.
authors.forename: Sanja
authors.initials: S
authors.lastname: Andric
authors.affiliation: Clinic for Psychiatry, Clinical Centre of Serbia, Belgrade, Serbia.
authors.forename: Marina
authors.initials: M
authors.lastname: Mihaljevic
authors.affiliation: Special Hospital for Psychiatric Disorders Kovin, Kovin, Serbia.
authors.forename: Tijana
authors.initials: T
authors.lastname: Mirjanic
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D010551:Personality; D010555:Personality Inventory; D011618:Psychotic Disorders / Q000150:complications / Q000523:psychology* / Q000628:therapy*; D012559:Schizophrenia / Q000150:complications; D012565:Schizophrenic Psychology; D055771:Serbia; D013997:Time Factors; D061665:Time-to-Treatment; D055815:Young Adult
keywords: duration of untreated psychosis; personality; psychosis; schizophrenia; serbia