title: ST Segment Elevation Myocardial Infarction Due to Severe Ostial Left Main Stem Stenosis in a Patient with Syphilitic Aortitis.
abstract: Cardiovascular manifestations of tertiary syphilis infections are uncommon, but represent an important cause of mortality and morbidity. Syphilitic aortitis is characterized by aortic regurgitation, dilatation of ascending aorta and ostial coronary artery lesions. We report a case of 36 years old man admitted to our hospital for acute anterior ST segment elevation myocardial infarction complicated with cardiogenic shock (hypotension 75/50 mmHg). Transthoracic echocardiography revealed a dilated left ventricle with severe systolic dysfunction (ejection fraction = 25%), severe mitral regurgitation, moderate aortic regurgitation and mildly dilated ascending aorta. Coronary angiography showed a severe ostial lesion of left main coronary artery which was treated by urgent stent implantation and an intra-aortic contrapulsation balloon was implanted. Blood tests for syphilitic infection were positive. The patient was discharged with treatment including benzathine penicillin. In our case, we present an acute manifestation of a syphilitic ostial left main stenosis treated by primary percutaneous coronary intervention in acute myocardial infarction. Long term follow-up of the patient is crucial as a result of potential rapid in-stent restenosis caused by continuous infection of the ascending aorta. This case is particular because it shows that syphilitic aortitis can be diagnosed in acute settings, like ST segment elevation myocardial infarction.
authors.forename: L M
authors.initials: LM
authors.lastname: Predescu
authors.forename: L
authors.initials: L
authors.lastname: Zarma
authors.forename: P
authors.initials: P
authors.lastname: Platon
authors.forename: M
authors.initials: M
authors.lastname: Postu
authors.forename: A
authors.initials: A
authors.lastname: Bucsa
authors.forename: M
authors.initials: M
authors.lastname: Croitoru
authors.forename: B
authors.initials: B
authors.lastname: Prodan
authors.forename: O
authors.initials: O
authors.lastname: Chioncel
authors.forename: D
authors.initials: D
authors.lastname: Deleanu
mesh_terms: D000328:Adult; D001022:Aortic Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology; D017023:Coronary Angiography; D023921:Coronary Stenosis / Q000150:complications* / Q000000981:diagnostic imaging; D004562:Electrocardiography; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000000981:diagnostic imaging / Q000209:etiology; D009203:Myocardial Infarction / Q000175:diagnosis / Q000209:etiology*; D013589:Syphilis, Cardiovascular / Q000150:complications* / Q000175:diagnosis; D014463:Ultrasonography