title: Preoperative diffusion-weighted imaging value of rectal cancer: preoperative T staging and correlations with histological T stage.
abstract: OBJECTIVE
  To assess the ability of diffusion-weighted imaging (DWI) for evaluating T stage and correlation with histological T stage of rectal cancer.
  
  
  METHODS
  The diagnostic accuracy, sensitivity, and specificity of T2WI and DWI combined with T2WI for T stage were evaluated. Mean tumor apparent diffusion coefficient (ADC) was compared with histological T stage.
  
  
  RESULTS
  There were no significant differences in the diagnostic accuracy, sensitivity, and specificity no matter what kind of T stage was concerned. The difference between ADC values and histological T stage were significantly different.
  
  
  CONCLUSIONS
  DWI was useful for evaluating T stage of rectal cancer. The ADC may predict the histological grade.
authors.affiliation: Medical Imaging Center, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China; Department of Radiology, Affiliated Changshu Hospital of Soochow University, 1 Shuyuan Road, Changshu, Jiangsu 215500, China.
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Lu
authors.affiliation: Medical Imaging Center, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215006, China. Electronic address: hch_sz5305@163.com.
authors.forename: Chun-Hong
authors.initials: CH
authors.lastname: Hu
authors.affiliation: Department of Radiology, Affiliated Changshu Hospital of Soochow University, 1 Shuyuan Road, Changshu, Jiangsu 215500, China.
authors.forename: Wei-Xin
authors.initials: WX
authors.lastname: Qian
authors.affiliation: Department of Radiology, Affiliated Changshu Hospital of Soochow University, 1 Shuyuan Road, Changshu, Jiangsu 215500, China.
authors.forename: Wen-Hong
authors.initials: WH
authors.lastname: Cao
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D000328:Adult; D000368:Aged; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D012004:Rectal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
keywords: Diffusion-weighted imaging; Magnetic resonance image; Prognosis; Rectal cancer; T stage