title: 18F-Fluorocholine PET/CT Finding of a Vertebral Hemangioma.
abstract: The uptake of F-fluorocholine (FCH), a radiopharmaceutical used to study patients with prostate cancer, follow both the phosphorylcholine and acetylcholine synthesis. FCH uptake is not specific of neoplastic cells because phospholipids are a structural constituent of the membrane of all cells. Thus, PET/CT with FCH show several areas of physiologic uptake. The skeleton concentrates only mild amounts of FCH, thus a diffuse faint uptake of the radiopharmaceutical is present at a PET/CT study. Herein we present the case of a patient in which PET/CT evidenced a sharply defined vertebral "cold" area of reduced FCH uptake corresponding to a vertebral hemangioma.
authors.affiliation: From the Fondazione Poliambulanza Istituto Ospedaliero, Brescia, Italy.
authors.forename: Giordano
authors.initials: G
authors.lastname: Savelli
authors.forename: Valentina
authors.initials: V
authors.lastname: Perotti
authors.forename: Edoardo
authors.initials: E
authors.lastname: Rosso
authors.forename: Claudio
authors.initials: C
authors.lastname: Pizzocaro
authors.forename: Silvia
authors.initials: S
authors.lastname: Magnaldi
mesh_terms: D002794:Choline / Q000031:analogs & derivatives*; D006391:Hemangioma / Q000000981:diagnostic imaging*; D006801:Humans; D008297:Male; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D019275:Radiopharmaceuticals; C514960:fluorocholine; D002794:Choline