title: Long-Term Retrospective Evaluation of Dental Implants Placed in Resorbed Jaws Reconstructed With Appositional Fresh-Frozen Bone Allografts.
abstract: BACKGROUND
  The aim of this study was to evaluate the outcome of fresh-frozen bone allografts in preprosthetic surgery for implant placement purposes.
  
  
  METHODS
  The cohort comprised 45 patients treated with fresh-frozen bone block grafts and dental implants. Clinical and radiological evaluations were performed to evaluate the survival rate. The data were statistically analyzed with the Kaplan-Meier estimator to assess the influence of possible predictors of implant failure on survival.
  
  
  RESULTS
  Overall, 262 implants were retrospectively analyzed. The survival rate was 90.84% over a mean follow-up of 50 months. Comparing the donor site and the position of the implants, no statistically significant differences could be detected (P = 0.7194 and P = 0.2901, respectively), whereas sex resulted in a marginally statistically significant difference (P = 0.0581). When considering age categorized on the median value (≤55/>55 years), age resulted in a statistically significant difference (P = 0.0340), with higher failures found in older people.
  
  
  CONCLUSIONS
  Implant loss was strictly related to the lack of primary osseointegration. Female sex and old age were found to be risk factors, which could negatively influence implant survival.
authors.affiliation: *Professor and Chairman, Department of Dental Implants, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. †Resident, Department of Dental Implants, Maxillofacial and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. ‡Assistant Professor, Department of Dental Implants, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. §PhD Fellow, Department of Dental Implants, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. ¶Assistant Professor, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy. ‖Resident, Department of Dental Implants, Maxillofacial Surgery and Odontostomatology Unit, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy. #Full Professor, Dental Clinic Director, Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Maiorana
authors.forename: Pier Paolo
authors.initials: PP
authors.lastname: Poli
authors.forename: Andrea Enrico
authors.initials: AE
authors.lastname: Borgonovo
authors.forename: Davide
authors.initials: D
authors.lastname: Rancitelli
authors.forename: Anna Chiara
authors.initials: AC
authors.lastname: Frigo
authors.forename: Stefano
authors.initials: S
authors.lastname: Pieroni
authors.forename: Franco
authors.initials: F
authors.lastname: Santoro
mesh_terms: D000328:Adult; D000368:Aged; D064591:Allografts; D016025:Bone Transplantation / Q000379:methods*; D003757:Dental Implantation / Q000379:methods*; D015921:Dental Implants; D017268:Dental Prosthesis Retention; D005260:Female; D006801:Humans; D008297:Male; D063175:Mandibular Reconstruction / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D015921:Dental Implants