title: Zirconium (IV)-based metal organic framework (UIO-67) as efficient sorbent in dispersive solid phase extraction of plant growth regulator from fruits coupled with HPLC fluorescence detection.
abstract: A stable zirconium (Ⅳ)-based metal organic frameworks (UIO-67) material possessing good chemical, thermal and water stability was synthesized and applied as a sorbent for the dispersive solid phase extraction (DSPE) of 8 plant growth regulators (PGRs) in fruit samples. Fluorescence labeling combined with high performance liquid chromatography fluorescence detection (HPLC-FLD), was used to quantify the target analytes. Characterization of the UIO-67 material was performed by X-ray diffraction(XRD) and scanning electron microscopy (SEM). The experimental parameters, such as amount of UIO-67, type and volume of eluting solvent, adsorption and desorption time, were optimized. Under the optimized conditions, good linearity was observed in the range of 10-1000 pmol/mL with R(2)>0.9989. The limits of detection and limits of quantification were in the range of 0.21-0.57ng/mL and 0.81-1.91ng/mL, respectively. The intra-day and inter-day precisions (based on the relative standard deviation, n=3) of the PGR derivatives were under 3.1% and 5.3% respectively and the accuracies of the method for the PGRs were in the range from 89.3% to 102.3%. The developed method was successfully applied to analyze PGRs residues in fruit samples. The proposed method is proved to be simple, environment-friendly and inexpensive and it is feasible to directly use UIO-67 as sorbent to extract targets by varying conditions.
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China.
authors.forename: Lijie
authors.initials: L
authors.lastname: Liu
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China. Electronic address: xialian01@163.com.
authors.forename: Lian
authors.initials: L
authors.lastname: Xia
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China.
authors.forename: Chuanxiang
authors.initials: C
authors.lastname: Wu
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China.
authors.forename: Fengli
authors.initials: F
authors.lastname: Qu
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China.
authors.forename: Guoliang
authors.initials: G
authors.lastname: Li
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China.
authors.forename: Zhiwei
authors.initials: Z
authors.lastname: Sun
authors.affiliation: Key Laboratory of Life-Organic Analysis of Shandong Province, Qufu Normal University, Qufu, PR China; Key Laboratory of Pharmaceutical Intermediates and Analysis of Natural Medicine of Shandong Province, Qufu Normal University, Qufu 273165, China; Northwest Plateau Institute of Biology, Chinese Academy of Sciences, Xining, PR China. Electronic address: jmyou6304@163.com.
authors.forename: Jinmao
authors.initials: J
authors.lastname: You
mesh_terms: D002851:Chromatography, High Pressure Liquid; D005638:Fruit; D010937:Plant Growth Regulators; D052616:Solid Phase Extraction; D015040:Zirconium
chemical_list: D010937:Plant Growth Regulators; D015040:Zirconium
keywords: Dispersive solid phase extraction; Fruit samples; High-performance liquid chromatography (HPLC); Metal–organic framework; Plant growth regulator