title: DOGMA: domain-based transcriptome and proteome quality assessment.
abstract: Genome studies have become cheaper and easier than ever before, due to the decreased costs of high-throughput sequencing and the free availability of analysis software. However, the quality of genome or transcriptome assemblies can vary a lot. Therefore, quality assessment of assemblies and annotations are crucial aspects of genome analysis pipelines.
  
  
  
  We developed DOGMA, a program for fast and easy quality assessment of transcriptome and proteome data based on conserved protein domains. DOGMA measures the completeness of a given transcriptome or proteome and provides information about domain content for further analysis. DOGMA provides a very fast way to do quality assessment within seconds.
  
  
  
  DOGMA is implemented in Python and published under GNU GPL v.3 license. The source code is available on https://ebbgit.uni-muenster.de/domainWorld/DOGMA/ CONTACTS: e.dohmen@wwu.de or c.kemena@wwu.de
  
  
  
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Institute for Evolution and Biodiversity, University of Münster, Münster 48149, Germany Institute for Bioinformatics and Chemoinformatics, Westphalian University of Applied Sciences, Recklinghausen 45665, Germany.
authors.forename: Elias
authors.initials: E
authors.lastname: Dohmen
authors.affiliation: Institute for Evolution and Biodiversity, University of Münster, Münster 48149, Germany.
authors.forename: Lukas P M
authors.initials: LP
authors.lastname: Kremer
authors.affiliation: Institute for Evolution and Biodiversity, University of Münster, Münster 48149, Germany.
authors.forename: Erich
authors.initials: E
authors.lastname: Bornberg-Bauer
authors.affiliation: Institute for Evolution and Biodiversity, University of Münster, Münster 48149, Germany.
authors.forename: Carsten
authors.initials: C
authors.lastname: Kemena
mesh_terms: D019295:Computational Biology; D016678:Genome; D020543:Proteome; D012984:Software; D059467:Transcriptome
chemical_list: D020543:Proteome