title: Presacral and intrathoracic extramedullary hematopoiesis in a patient with β thalassemia minor.
abstract: Extramedullary hematopoiesis (EMH) is a rare disease characterized by the presence of hematopoietic elements outside the bone marrow as a compensatory phenomenon in several hematological diseases, including thalassemia. We report a 64-year-old man with epigastric pain of 3-months' duration radiated to the back. Imaging workup showed multiple paravertebral, retrosternal and presacral masses. Cytology findings obtained by CT-guided FNAC were compatible with the diagnosis of EMH. Peripheral blood smear confirmed the presence of β-thalassemia.
authors.affiliation: Department of Internal Medicine, University Hospital 12 de Octubre, Madrid, Spain.|Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Lalueza
authors.affiliation: Department of Internal Medicine, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Carlos Patricio
authors.initials: CP
authors.lastname: Silva
authors.affiliation: Department of Radiology, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Andrea
authors.initials: A
authors.lastname: Alcalá-Galiano
authors.affiliation: Department of Internal Medicine, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Estibaliz
authors.initials: E
authors.lastname: Arrieta
authors.affiliation: Department of Pathology, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: José Miguel
authors.initials: JM
authors.lastname: Cánovas
authors.affiliation: Department of Radiology, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: Calero
authors.affiliation: Department of Medicine, Faculty of Medicine, Universidad Complutense, Madrid, Spain.|Department of Respiratory Medicine, University Hospital 12 de Octubre, Madrid, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Álvarez
mesh_terms: D001853:Bone Marrow / Q000000981:diagnostic imaging*; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D061705:Image-Guided Biopsy; D008297:Male; D008875:Middle Aged; D012447:Sacrum; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed; D017086:beta-Thalassemia / Q000175:diagnosis*
keywords: mediastinum - nonhepatosplenic extramedullary hematopoiesis - paravertebral extramedullary hematopoiesis - presacral - retrosternal - thalassemia