title: Disposable microfluidic sensor arrays for discrimination of antioxidants.
abstract: A microfluidic colorimetric sensor array was developed for detection and identification of various antioxidants. The sensor was fabricated by a photolithographic method, and consists of an array of printed cross-responsive indicators. The microfluidic design also incorporates pre-activation spots to allow printing of chemically incompatible components separately. Separately printed oxidizer allowed an oxidation of adjacent redox indicators only when aqueous sample was added to the sensor cartridge. Antioxidants were primarily detected by measuring the extent of inhibition of this oxidation reaction. Using this flow-based technique, a clear differentiation of 8 different antioxidants and 4 different teas has been demonstrated with 98.5% sensitivity.
authors.affiliation: iSense, LLC 855 Maude Ave., Mountain View, CA 94040, USA; Sungkyunkwan University, School of Chemical Engineering, Suwon 440746, South Korea.
authors.forename: Seong H
authors.initials: SH
authors.lastname: Park
authors.affiliation: iSense, LLC 855 Maude Ave., Mountain View, CA 94040, USA.
authors.forename: Autumn
authors.initials: A
authors.lastname: Maruniak
authors.affiliation: iSense, LLC 855 Maude Ave., Mountain View, CA 94040, USA; Sungkyunkwan University, School of Chemical Engineering, Suwon 440746, South Korea.
authors.forename: Jisun
authors.initials: J
authors.lastname: Kim
authors.affiliation: Sungkyunkwan University, School of Chemical Engineering, Suwon 440746, South Korea. Electronic address: yigira@skku.edu.
authors.forename: Gi-Ra
authors.initials: GR
authors.lastname: Yi
authors.affiliation: iSense, LLC 855 Maude Ave., Mountain View, CA 94040, USA. Electronic address: slim@isensesystems.com.
authors.forename: Sung H
authors.initials: SH
authors.lastname: Lim
mesh_terms: D000975:Antioxidants; D003124:Colorimetry; D044085:Microfluidics; D010084:Oxidation-Reduction; D011327:Printing
chemical_list: D000975:Antioxidants
keywords: Antioxidants; Colorimetric sensors; Paper-based devices; Redox