title: [Cardiogenic shock due to spontaneous neonatal thrombosis of the abdominal aorta].
abstract: Neonatal arterial thrombosis is unusual and generally associated with an arterial umbilical catheter. Spontaneous aortic thrombosis is exceptional but its severity is related to high mortality rate and renovascular morbidity. We report here the observation of a 10-day-old term infant showing a large abdominal aortic thrombosis revealed by cardiogenic shock induced by systemic arterial hypertension. The resolution was fast following anticoagulant and antihypertensive therapy. Etiologic investigations showed renal failure and moderate hyperhomocysteinemia controlled by a vitamin supplement. Following this observation, we did a brief review of the neonatal spontaneous arterial thrombosis literature to discuss the neonatal hemostasis specific aspects. Management of infants presenting an arterial thrombosis varies depending on the hospital and there are no guidelines at this time concerning the etiologic investigation and treatment in France or internationally.
authors.affiliation: Unité de réanimation infantile et pédiatrique, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France. Electronic address: josephine.brice@gmail.com.
authors.forename: J
authors.initials: J
authors.lastname: Brice
authors.affiliation: Unité de réanimation infantile et pédiatrique, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Venot
authors.affiliation: Unité de réanimation infantile et pédiatrique, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
authors.forename: M
authors.initials: M
authors.lastname: Colinart-Thomas
authors.affiliation: Unité de réanimation infantile et pédiatrique, CHU de Reims, 45, rue Cognacq-Jay, 51092 Reims cedex, France.
authors.forename: P
authors.initials: P
authors.lastname: Morville
mesh_terms: D001012:Aorta, Abdominal / Q000000981:diagnostic imaging*; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000209:etiology; D007231:Infant, Newborn; D008297:Male; D012078:Renal Artery Obstruction / Q000000981:diagnostic imaging; D012770:Shock, Cardiogenic / Q000209:etiology*; D013927:Thrombosis / Q000150:complications* / Q000175:diagnosis