title: Long-term drug-resistant temporal lobe epilepsy associated with a mixed ganglioglioma and dysembryoplastic neuroepithelial tumor in an elderly patient.
abstract: BACKGROUND
  Mixed ganglioglioma and dysembryoplastic neuroepithelial tumor (DNET) is an extremely rare neuropathological diagnosis. The sparse number of patients described are children or young adults with long-term drug-resistant epilepsy.
  
  
  METHODS
  We report on a rare case of this tumor in a 61-year-old patient with an epilepsy duration of almost 60 years. This patient received an epilepsy surgery work-up with the intention to cure his drug-resistant epilepsy by performing a complete lesionectomy. The available literature on these mixed tumors is reviewed.
  
  
  CONCLUSIONS
  A contrast-enhancing mixed ganglioglioma and DNET can mimic a malignant tumor and appears not only in children and young adults, but also in the elderly patients with chronic epilepsy. A long-lasting epilepsy, in this case almost 60 years, can be completely cured by a complete lesionectomy.
authors.affiliation: Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands; Department of School of Mental Health and Neurosciences, School of Mental Health and Neurosciences, Maastricht University, Maastricht, The Netherlands; Academic Center for Epileptology, Maastricht University Medical Center, Maastricht, The Netherlands.
authors.forename: Olaf E M G
authors.initials: OE
authors.lastname: Schijns
authors.affiliation: Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands.
authors.forename: Jan
authors.initials: J
authors.lastname: Beckervordersandforth
authors.affiliation: Department of Epileptology, Academic Center for Epileptology, Kempenhaeghe, Heeze, The Netherlands.
authors.forename: Louis
authors.initials: L
authors.lastname: Wagner
authors.affiliation: Department of Neurosurgery, Maastricht University Medical Center, Maastricht, The Netherlands; Department of School of Mental Health and Neurosciences, School of Mental Health and Neurosciences, Maastricht University, Maastricht, The Netherlands.
authors.forename: Govert
authors.initials: G
authors.lastname: Hoogland
keywords: Dysembryoplastic neuroepithelial tumor; ganglioglioma; glioneuronal tumor; surgery; temporal lobe epilepsy