title: Single-Cell Genomics for Virology.
abstract: Single-cell sequencing technologies, i.e., single cell analysis followed by deep sequencing investigate cellular heterogeneity in many biological settings. It was only in the past year that single-cell sequencing analyses has been applied in the field of virology, providing new ways to explore viral diversity and cell response to viral infection, which are summarized in the present review.
authors.affiliation: Institute of Microbiology, University Hospital Center and University of Lausanne, Bugnon 48, CH-1011 Lausanne, Switzerland. Angela.Ciuffi@chuv.ch.
authors.forename: Angela
authors.initials: A
authors.lastname: Ciuffi
authors.affiliation: Institute of Microbiology, University Hospital Center and University of Lausanne, Bugnon 48, CH-1011 Lausanne, Switzerland. Sylvie.Ferreira-Rato@chuv.ch.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Rato
authors.affiliation: The J. Craig Venter Institute, 4120 Capricorn Lane, La Jolla, CA 92037, USA. atelenti@jcvi.org.
authors.forename: Amalio
authors.initials: A
authors.lastname: Telenti
mesh_terms: D023281:Genomics / Q000379:methods*; D054884:Host-Pathogen Interactions; D006801:Humans; D059010:Single-Cell Analysis / Q000379:methods*; D014773:Virology / Q000379:methods*; D014780:Viruses / Q000276:immunology* / Q000472:pathogenicity*
keywords: RNA-Seq; cell-to-cell variability; genomics; heterogeneity; microfluidics; proteomics; sequencing; single cell; transcriptomics; virus