title: [SSRI antidepressant use during pregnancy and the assessment of the risk-benefit ratio].
abstract: Studies report that between 6 and 13% of women experience symptoms of depression during pregnancy and the postpartum period. The abundant data available make selective serotonin reuptake inhibitors (SSRIs) the first line treatment in pregnancy when a pharmacological treatment is required. Risks associated with the use of SSRIs during pregnancy are limited (moderate effect size) and are often not distinguishable from those inherent to the mother's disease. Yet, several questions regarding the SSRI safety profile for the unborn child are still under debate or require additional epidemiological data. The decision of SSRI use during pregnancy needs an individual evaluation of the risk-benefit balance.
authors.forename: Etienne
authors.initials: E
authors.lastname: Weisskopf
authors.forename: Céline J Fischer
authors.initials: CJ
authors.lastname: Fumeaux
authors.forename: Myriam
authors.initials: M
authors.lastname: Bickle Graz
authors.forename: Mathild Morisod
authors.initials: MM
authors.lastname: Harari
authors.forename: Manuella
authors.initials: M
authors.lastname: Epiney
authors.forename: Cristina Borradori
authors.initials: CB
authors.lastname: Tolsa
authors.forename: Sylvie
authors.initials: S
authors.lastname: Rouiller
authors.forename: Jean-François
authors.initials: JF
authors.lastname: Tolsa
authors.forename: Chin B
authors.initials: CB
authors.lastname: Eap
authors.forename: Yvan
authors.initials: Y
authors.lastname: Vial
authors.forename: Chantal
authors.initials: C
authors.lastname: Csajka
authors.forename: Alice
authors.initials: A
authors.lastname: Panchaud
mesh_terms: D000928:Antidepressive Agents / Q000009:adverse effects / Q000627:therapeutic use; D003866:Depressive Disorder / Q000150:complications / Q000188:drug therapy*; D005260:Female; D006801:Humans; D010818:Practice Patterns, Physicians'; D011247:Pregnancy; D011248:Pregnancy Complications / Q000139:chemically induced / Q000188:drug therapy* / Q000523:psychology; D018570:Risk Assessment; D017367:Selective Serotonin Reuptake Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*
chemical_list: D000928:Antidepressive Agents; D017367:Selective Serotonin Reuptake Inhibitors