title: Numerical analysis of blood flow through an elliptic stenosis using large eddy simulation.
abstract: The presence of a stenosis caused by the abnormal narrowing of the lumen in the artery tree can cause significant variations in flow parameters of blood. The original flow, which is believed to be laminar in most situations, may turn out to turbulent by the geometric perturbation created by the stenosis. Flow may evolve to fully turbulent or it may relaminarise back according to the intensity of the perturbation. This article reports the numerical simulation of flow through an eccentrically located asymmetric stenosis having elliptical cross section using computational fluid dynamics. Large eddy simulation technique using dynamic Smagorinsky sub-grid scale model is applied to capture the turbulent features of flow. Analysis is carried out for two situations: steady inflow as ideal condition and pulsatile inflow corresponding to the actual physiological condition in common carotid artery. The spatially varying pulsatile inflow waveforms are mathematically derived from instantaneous mass flow measurements available in the literature. Carreau viscosity model is used to estimate the effect of non-Newtonian nature of blood. The present simulations for steady and pulsatile conditions show that post-stenotic flow field undergoes transition to turbulence in all cases. The characteristics of mean and turbulent flow fields have been presented and discussed in detail.
authors.affiliation: Fluid Dynamics Laboratory, College of Engineering, Thiruvananthapuram, India.
authors.forename: E
authors.initials: E
authors.lastname: Jabir
authors.affiliation: Fluid Dynamics Laboratory, College of Engineering, Thiruvananthapuram, India anillal@cet.ac.in.
authors.forename: S Anil
authors.initials: SA
authors.lastname: Lal
mesh_terms: D050197:Atherosclerosis / Q000503:physiopathology*; D001783:Blood Flow Velocity / Q000502:physiology; D001809:Blood Viscosity / Q000502:physiology; D016893:Carotid Stenosis / Q000503:physiopathology; D003198:Computer Simulation; D003251:Constriction, Pathologic / Q000503:physiopathology; D006801:Humans; D057446:Hydrodynamics; D008955:Models, Cardiovascular; D011673:Pulsatile Flow / Q000502:physiology
keywords: Elliptic stenosis; computational fluid dynamics; large eddy simulation; turbulent blood flow