title: Severe Sepsis Associated with Lemierre's Syndrome: A Rare but Life-Threatening Disease.
abstract: Background. The incidence of Lemierre's syndrome has increased in the past decade. This posttonsillitis complication may be life threatening. Case Presentation. A 19-year-old patient was admitted to Surgical Intensive Care Unit of a French University Hospital for high fever, low blood pressure, and haemoptysis following a sore throat episode. Blood analysis revealed a thrombopenia, an acute renal failure, and an elevated lactate serum. Fusobacterium necrophorum was found in blood cultures. Computed tomography of the neck and lungs confirmed the diagnosis of Lemierre's syndrome: pleural effusions, bilateral lung infiltrates, and an internal jugular vein thrombosis. Fluid administration and antibiotic treatment were quickly initiated. Patient left the unit four days after his admission without any organ dysfunction. Conclusion. Lemierre's syndrome may lead to multiorgan dysfunction and should be rapidly identified.
authors.affiliation: Intensive Care Unit, Anaesthesia and Critical Care Department, University Hospital of Rennes, 2 rue Henri Le Guilloux, 35000 Rennes, France.
authors.forename: Audrey
authors.initials: A
authors.lastname: Tawa
authors.affiliation: Intensive Care Unit, Anaesthesia and Critical Care Department, University Hospital of Rennes, 2 rue Henri Le Guilloux, 35000 Rennes, France.
authors.forename: Raphaëlle
authors.initials: R
authors.lastname: Larmet
authors.affiliation: Intensive Care Unit, Anaesthesia and Critical Care Department, University Hospital of Rennes, 2 rue Henri Le Guilloux, 35000 Rennes, France; Inserm U991, Rennes, France.
authors.forename: Yannick
authors.initials: Y
authors.lastname: Malledant
authors.affiliation: Intensive Care Unit, Anaesthesia and Critical Care Department, University Hospital of Rennes, 2 rue Henri Le Guilloux, 35000 Rennes, France; Inserm U991, Rennes, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Seguin