title: [Cost-effectiveness of Antipsychotics in the Maintenance Treatment of Schizophrenia in Colombia].
abstract: OBJECTIVE
  Assess the cost-effectiveness of the antipsychotics for treatment of schizophrenia.
  
  
  METHODS
  A five-year Markov model was built form patients with schizophrenia on the stage of maintenance. Costs were taken from the perspective of the Colombian health care system (Sistema General de Seguridad Social en Salud). The effectiveness was measured in years of life under the same maintenance plan.
  
  
  RESULTS
  The Markov model indicated clozapine as the as the most cost-effective alternative between the first line antipsychotics and haloperidol is it when comparing other antipsychotics.
  
  
  CONCLUSIONS
  Clozapine it's the cost-effectiveness strategy among the first line of antipsychotics and haloperidol is it among the other antipsychotics. Strategies prioritizing the use of cost-effective antipsychotics could improve the resources allocation in the Colombian health care system.
authors.affiliation: Economista con M. Sc. Investigación en economía. Docente, Departamento de Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana, Bogotá, Colombia. Electronic address: quitianh@javeriana.edu.co.
authors.forename: Hoover
authors.initials: H
authors.lastname: Quitian Reyes
authors.affiliation: Economista. Asistente de investigación, Departamento de Epidemiología Clínica y Bioestadística, Pontificia Universidad Javeriana. Carrera 7 No. 40 - 62, Bogotá, Colombia.
authors.forename: Jair Alberto
authors.initials: JA
authors.lastname: Arciniegas Barrera
authors.affiliation: Médica psiquiatra, magístra en Epidemiología Clínica. Profesora asistente del departamento de Psiquiatría y Salud Mental. Pontificia Universidad Javeriana, Bogotá, Colombia.
authors.forename: Adriana
authors.initials: A
authors.lastname: Bohórquez Peñaranda
authors.affiliation: Médico psiquiatra, psicoanalista, psiquiatra de enlace, magíster en Epidemiología Clínica. Profesor titular y Director del Departamento de Epidemiología Clínica y Bioestadística. Pontificia Universidad Javeriana. Hospital Universitario San Ignacio, Bogotá, Colombia.
authors.forename: Carlos
authors.initials: C
authors.lastname: Gómez Restrepo
mesh_terms: D014150:Antipsychotic Agents / Q000191:economics* / Q000627:therapeutic use; D003024:Clozapine / Q000191:economics / Q000627:therapeutic use; D003105:Colombia; D003362:Cost-Benefit Analysis; D016527:Drug Costs / Q000706:statistics & numerical data*; D006220:Haloperidol / Q000191:economics / Q000627:therapeutic use; D006801:Humans; D008390:Markov Chains; D018803:Models, Economic; D012559:Schizophrenia / Q000188:drug therapy* / Q000191:economics
chemical_list: D014150:Antipsychotic Agents; D003024:Clozapine; D006220:Haloperidol
keywords: Agentes antipsicóticos; Antipsychotic agents; Análisis de costo efectividad; Cost effectiveness analysis; Esquizofrenia; Schizophrenia