title: Review of Mouse and Human Dendritic Cell Subsets.
abstract: Dendritic cells are specialized antigen-presenting cells that initiate and orient immune responses. Numerous studies in mice and humans have shown that dendritic cells are heterogeneous and comprise several subsets that can be distinguished by their surface phenotype, ontogeny, and molecular signature. This review gives an overview of mouse and human dendritic cell subsets and their defining features and summarizes the current knowledge of dendritic cell subsets' functional specialization in terms of antigen presentation.
authors.affiliation: Institut Curie, 26 rue d'Ulm, 75248, Paris Cedex 05, France. elodie.segura@curie.fr.|INSERM U932, 26 rue d'Ulm, 75248, Paris Cedex 05, France. elodie.segura@curie.fr.
authors.forename: Elodie
authors.initials: E
authors.lastname: Segura
mesh_terms: D000818:Animals; D017951:Antigen Presentation; D015415:Biomarkers / Q000378:metabolism; D019070:Cell Lineage; D003713:Dendritic Cells / Q000166:cytology* / Q000276:immunology; D006801:Humans; D051379:Mice
chemical_list: D015415:Biomarkers
keywords: Antigen presentation; Dendritic cells; Human; Mouse; Subsets