title: Detection of synchronous primary tumours and previously undetected metastases in 736 dogs with neoplasia undergoing CT scans for diagnostic, staging and/or radiation treatment planning purposes.
abstract: The purpose of our study was to describe synchronous primary tumours and previously undetected metastases in 736 dogs with confirmed neoplasia in which computed tomography (CT) scans were performed for diagnostic, staging and/or radiation treatment planning purposes. All CTs were reviewed by a radiologist. Tumour-associated CT abnormalities were detected in 38/736 (5%), including confirmed or suspected synchronous primary neoplasms (n = 24), metastases of the primary tumour (n = 9) or both (n = 3). In lymph nodes (LN) that were considered abnormal on CT scan and were aspirated, 23% contained metastasis, and 6% of 'normal' appearing LN that were aspirated contained metastasis. Thorough evaluation of CTs and routine aspiration of regional LN are critical because results affect recommendations to perform additional staging tests and treatment for the primary and secondary tumour(s).
authors.affiliation: Department of Clinical Sciences (College of Veterinary Medicine) and Comparative Medicine Institute, North Carolina, State University, Raleigh, NC, 27607, USA.
authors.forename: L M
authors.initials: LM
authors.lastname: Magestro
authors.affiliation: Department of Clinical Sciences (College of Veterinary Medicine) and Comparative Medicine Institute, North Carolina, State University, Raleigh, NC, 27607, USA.
authors.forename: T L
authors.initials: TL
authors.lastname: Gieger
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000175:diagnosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000532:radiotherapy; D004285:Dogs; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D009367:Neoplasm Staging / Q000379:methods / Q000662:veterinary*; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis / Q000000981:diagnostic imaging / Q000532:radiotherapy / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000662:veterinary
keywords: diagnostic imaging; radiotherapy; staging tests