title: Patient Satisfaction With Collagenase.
abstract: OBJECTIVE
  To establish patient satisfaction after collagenase clostridium histolyticum (CCH) injection.
  
  
  METHODS
  In a cross-sectional study, 213 patients who had been treated for Dupuytren disease with CCH were reviewed between 37 and 1421 days after injection.
  
  
  RESULTS
  A total of 73% of the patients were very satisfied or satisfied, and 21% were dissatisfied; 75% would probably or definitely have CCH again, whereas 17% probably or definitely would not. We found that satisfaction and willingness to undergo a second treatment decreased over time and had a negative relationship with recurrence. Dissatisfaction was greater in those with a poor initial outcome but not in those with an initial complication. Of 212 patients, 78 had previously experienced surgery for Dupuytren disease of whom 71% would prefer CCH to surgery and 15% the converse. Satisfaction shows a relationship with function as measured by both QuickDASH and the Southampton Dupuytren Scoring Scheme.
  
  
  CONCLUSIONS
  Patient satisfaction with CCH is generally high but deteriorates over time as the disease recurs. To manage patient expectation, this issue should be made explicit to patients in the consent process.
  
  
  CONCLUSIONS
  Overall satisfaction with CCH is high, with initial satisfaction rates especially good. Forewarning of complications and recurrence can help maintain satisfaction levels.
authors.affiliation: University Hospital Southampton and University of Southampton, Southampton, United Kingdom.
authors.forename: Jack
authors.initials: J
authors.lastname: Bradley
authors.affiliation: University Hospital Southampton and University of Southampton, Southampton, United Kingdom. Electronic address: davidwarwick@me.com.
authors.forename: David
authors.initials: D
authors.lastname: Warwick
mesh_terms: D003430:Cross-Sectional Studies; D004387:Dupuytren Contracture / Q000000981:diagnostic imaging / Q000188:drug therapy*; D005260:Female; D005500:Follow-Up Studies; D018737:Hand Strength; D006801:Humans; D015552:Injections, Intralesional; D008297:Male; D003012:Microbial Collagenase / Q000008:administration & dosage*; D017060:Patient Satisfaction / Q000706:statistics & numerical data*; D020127:Recovery of Function; D057566:Self Report; D012720:Severity of Illness Index; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
chemical_list: D003012:Microbial Collagenase
keywords: Collagenase; collagenase clostridium histolyticum; complications; patient-related outcome measures; satisfaction