title: A case of primary pulmonary NK/T cell lymphoma presenting as pneumonia.
abstract: Primary pulmonary lymphoma, particularly non-B cell lymphomas involving lung parenchyma, is very rare. A 46-year-old male was admitted to the hospital with fever and cough. Chest X-ray showed left lower lobe consolidation, which was considered pneumonia. However, because the patient showed no response to empirical antibiotic therapy, bronchoscopic biopsy was performed for proper diagnosis. The biopsied specimen showed infiltrated atypical lymphocytes with angiocentric appearance. On immunohistochemical staining, these atypical cells were positive for CD3, CD30, CD56, MUM-1, and granzyme B, and labeled for Epstein-Barr virus encoded RNA in situ hybridization. These findings were consistent with NK/T cell lymphoma. We report on a case of primary pulmonary NK/T cell lymphoma presenting as pneumonic symptoms and review the literature on the subject.
authors.affiliation: Department of Pathology, Gil Medical Center, Gachon University School of Medicine, Incheon, Republic of Korea.
authors.forename: Sangho
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Pathology, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Republic of Korea.
authors.forename: Bongkyung
authors.initials: B
authors.lastname: Shin
authors.affiliation: Department of Internal Medicine, Chungju Hospital, School of Medicine, Konkuk University, Chungju, Republic of Korea.
authors.forename: Hyungseok
authors.initials: H
authors.lastname: Yoon
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Chungju Hospital, School of Medicine, Konkuk University, Chungju, Republic of Korea.
authors.forename: Jung Yeon
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Pulmonary and Critical Care Medicine, Chungju Hospital, School of Medicine, Konkuk University, Chungju, Republic of Korea.
authors.forename: Gyu Rak
authors.initials: GR
authors.lastname: Chon
keywords: Epstein–Barr virus; Lymphoma; NK-T cell lymphoma; Pneumonia