title: The Promise of Patient-Reported Outcomes Measurement Information System-Turning Theory into Reality: A Uniform Approach to Patient-Reported Outcomes Across Rheumatic Diseases.
abstract: PROMIS, the Patient-Reported Outcomes Measurement Information System, is opening new possibilities to explore and learn how patient (or proxy) self-report of core symptoms and health-related quality of life can meaningfully advance clinical research and patient care. PROMIS leverages Item Response Theory to agnostically assess, across diseases and conditions or clinical settings, numerous universally applicable core "domains" of health (symptoms and functioning) from the patient perspective. Importantly, PROMIS is enabling the testing and adoption of computerized adaptive testing, which holds great potential to minimize patient burden while maximizing accuracy.
authors.affiliation: Rheumatic Diseases Clinical Program, National Institute of Arthritis and Musculoskeletal and Skin Diseases, One Democracy Plaza, 6701 Democracy Boulevard, Suite 800, Bethesda, MD 20892-4872, USA. Electronic address: james.witter@nih.gov.
authors.forename: James P
authors.initials: JP
authors.lastname: Witter
mesh_terms: D063005:Health Information Systems; D006304:Health Status; D006801:Humans; D000071066:Patient Reported Outcome Measures; D019727:Proxy; D011788:Quality of Life; D012216:Rheumatic Diseases / Q000503:physiopathology* / Q000628:therapy; D057566:Self Report; D014481:United States
keywords: PROMIS; Patient assessment; Universal; Validation