title: A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials.
abstract: Test strips that in combination with a portable fluorescence reader or digital camera can rapidly and selectively detect chemical warfare agents (CWAs) such as Tabun (GA), Sarin (GB), and Soman (GD) and their simulants in the gas phase have been developed. The strips contain spots of a hybrid indicator material consisting of a fluorescent BODIPY indicator covalently anchored into the channels of mesoporous SBA silica microparticles. The fluorescence quenching response allows the sensitive detection of CWAs in the μg m(-3) range in a few seconds.
authors.affiliation: Chemical and Optical Sensing Division (1.9), Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Strasse 11, 12489, Berlin, Germany.
authors.forename: Estela
authors.initials: E
authors.lastname: Climent
authors.affiliation: Chemical and Optical Sensing Division (1.9), Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Strasse 11, 12489, Berlin, Germany.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Biyikal
authors.affiliation: Chemical and Optical Sensing Division (1.9), Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Strasse 11, 12489, Berlin, Germany.
authors.forename: Kornelia
authors.initials: K
authors.lastname: Gawlitza
authors.affiliation: Laboratory of Toxic Compounds, National Institute for Nuclear, Chemical and Biological Protection, Kamenná 71, 262 31, Milín, Czech Republic.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Dropa
authors.affiliation: Laboratory of Toxic Compounds, National Institute for Nuclear, Chemical and Biological Protection, Kamenná 71, 262 31, Milín, Czech Republic.
authors.forename: Martin
authors.initials: M
authors.lastname: Urban
authors.affiliation: Organic Chemistry Department, Universitat de Valencia, Dr. Moliner 50, 46100, Burjassot, Valencia, Spain.|Research Institute for Molecular Recognition and Technological, Development (IDM), Unidad Mixta Universidad Politécnica de Valencia-, Universidad de Valencia, Spain.|CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Costero
authors.affiliation: Research Institute for Molecular Recognition and Technological, Development (IDM), Unidad Mixta Universidad Politécnica de Valencia-, Universidad de Valencia, Spain.|CIBER de Bioingeniería, Biomateriales y Nanomedicina (CIBER-BBN), Spain.|Department of Chemistry, Universidad Politécnica de Valencia, Camino de Vera s/n, 46022, Valencia, Spain.
authors.forename: Ramón
authors.initials: R
authors.lastname: Martínez-Máñez
authors.affiliation: Chemical and Optical Sensing Division (1.9), Bundesanstalt für Materialforschung und -prüfung (BAM), Richard-Willstätter-Strasse 11, 12489, Berlin, Germany. knut.rurack@bam.de.
authors.forename: Knut
authors.initials: K
authors.lastname: Rurack
mesh_terms: D001896:Boron Compounds / Q000737:chemistry*; D002619:Chemical Warfare Agents / Q000032:analysis / Q000737:chemistry*; D000067397:Nerve Agents / Q000032:analysis / Q000737:chemistry*; D010755:Organophosphates / Q000032:analysis / Q000737:chemistry*; D011517:Prothrombin Time / Q000379:methods*; D012524:Sarin / Q000032:analysis / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D012999:Soman / Q000032:analysis / Q000737:chemistry*
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D002619:Chemical Warfare Agents; D000067397:Nerve Agents; D010755:Organophosphates; D012822:Silicon Dioxide; D012999:Soman; D012524:Sarin; C009374:tabun
keywords: chemical warfare agents; fluorescence; hybrid sensor materials; nerve gases; test strip analysis