title: Long-term follow-up after radio-frequency catheter-based denervation in patients with resistant hypertension.
abstract: The aim of this single-center study was to asses the long-term clinical data of patients with resistant hypertension who underwent radiofrequency renal denervation (RND).
  
  
  METHODS
  Out of 86 patients with resistant-hypertension, 15 pts fulfilled the study criteria for performing RND using Simplicity system by Medtronic.
  
  
  RESULTS
  Baseline office systolic BP was 204±32.7 and diastolic BP 107.7±15.1mmHg. Baseline 24h ambulatory systolic BP was 151.8±13.9 and diastolic BP 86.8±13.8mmHg. Patients were treated with an average of 5 antihypertensive agents in maximally tolerated doses (including diuretic) during the whole trial and were followed up at 1,6,24month after RND. At every appointment an echocardiography, blood test, and blood pressure (office and ABMP) measurements were performed. The mean reduction in office systolic (SBP) and diastolic (DBP) blood pressure were the following: There were no procedural complications. All denervations were performed by experienced operator.
  
  
  CONCLUSIONS
  We regard RND as a safe and effective procedure in resistant hypertension, although more studies and trials are needed to find the most adequate model of a patient that would be a good responder to RND.
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: mskowerski@yahoo.co.uk.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Skowerski
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: tomaszroleder@gmail.com.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Roleder
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: kasiabanska@op.pl.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Bańska-Kisiel
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: piotr.pysz@gmail.com.
authors.forename: Piotr
authors.initials: P
authors.lastname: Pysz
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: aochala@poczta.onet.pl.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Ochała
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: wojtek.wojakowski@gmail.com.
authors.forename: Wojciech
authors.initials: W
authors.lastname: Wojakowski
authors.affiliation: 2nd Department of Cardiology, Medical University of Silesia, Katowice, Poland. Electronic address: zbgasior@gmail.com.
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Gąsior
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D001795:Blood Pressure Determination; D018660:Blood Pressure Monitoring, Ambulatory; D017115:Catheter Ablation / Q000379:methods*; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000188:drug therapy / Q000601:surgery*; D007668:Kidney / Q000294:innervation* / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013562:Sympathectomy / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000959:Antihypertensive Agents
keywords: Catheter based renal sympathetic denervation; Renal denervation; Resistant-hypertension