title: Effect of Mobile Phone-Induced Electromagnetic Field on Brain Hemodynamics and Human Stem Cell Functioning: Possible Mechanistic Link to Cancer Risk and Early Diagnostic Value of Electronphotonic Imaging.
abstract: The mobile phones (MP) are low power radio devices which work on electromagnetic fields (EMFs), in the frequency range of 900-1800 MHz. Exposure to MPEMFs may affect brain physiology and lead to various health hazards including brain tumors. Earlier studies with positron emission tomography (PET) have found alterations in cerebral blood flow (CBF) after acute exposure to MPEMFs. It is widely accepted that DNA double-strand breaks (DSBs) and their misrepair in stem cells are critical events in the multistage origination of various leukemia and tumors, including brain tumors such as gliomas. Both significant misbalance in DSB repair and severe stress response have been triggered by MPEMFs and EMFs from cell towers. It has been shown that stem cells are most sensitive to microwave exposure and react to more frequencies than do differentiated cells. This may be important for cancer risk assessment and indicates that stem cells are the most relevant cellular model for validating safe mobile communication signals. Recently developed technology for recording the human bio-electromagnetic (BEM) field using Electron photonic Imaging (EPI) or Gas Discharge Visualisation (GDV) technique provides useful information about the human BEM. Studies have recorded acute effects of Mobile Phone Electromagnetic Fields (MPEMFs) using EPI and found quantifiable effects on human BEM field. Present manuscript reviews evidences of altered brain physiology and stem cell functioning due to mobile phone/cell tower radiations, its association with increased cancer risk and explores early diagnostic value of EPI imaging in detecting EMF induced changes on human BEM.
authors.forename: Hemant
authors.initials: H
authors.lastname: Bhargav
authors.forename: T M
authors.initials: TM
authors.lastname: Srinivasan
authors.forename: S
authors.initials: S
authors.lastname: Varambally
authors.forename: B N
authors.initials: BN
authors.lastname: Gangadhar
authors.forename: Prasad
authors.initials: P
authors.lastname: Koka
mesh_terms: D001921:Brain / Q000098:blood supply / Q000473:pathology / Q000528:radiation effects; D001932:Brain Neoplasms / Q000209:etiology* / Q000473:pathology; D040421:Cell Phone; D053903:DNA Breaks, Double-Stranded / Q000528:radiation effects; D004574:Electromagnetic Fields / Q000009:adverse effects*; D006439:Hemodynamics / Q000528:radiation effects; D006801:Humans; D012307:Risk Factors; D013234:Stem Cells / Q000473:pathology / Q000528:radiation effects*