title: Congenital malformations and other reproductive losses in goats due to poisoning by Poincianella pyramidalis (Tul.) L.P. Queiroz (=Caesalpinia pyramidalis Tul.).
abstract: In the semiarid region of Brazil, in areas with vegetation composed mainly of Poincianella pyramidalis, several cases of congenital malformation and reproductive losses were observed in goats and sheep from 2012 to 2014. To determine the teratogenic effect of P. pyramidalis, two groups of eight goats each were used. Goats from Group 1 received fresh P. pyramidalis, harvested daily, as the only roughage during the whole breeding and pregnancy period. Goats in Group 2 (control) received Cynodon dactylon (tifton) hay free choice. Ultrasound examination for pregnancy diagnosis was performed every 28 days. Four goats from Group 1 were pregnant on day 28 but not on day 56, suggesting embryonic death or abortion. Another goat from Group 1 died at day 70 of pregnancy, and the fetuses exhibited micrognathia. The other three goats bore six kids, three of which showed bone malformations in the limbs, spine, ribs, sternum, and head, including arthrogryposis, scoliosis and micrognathia. One kid also showed hypoplasia of the left pulmonary lobes. In the control group, all goats bore a total of 13 kids and none of them exhibited malformations. These results demonstrated that P. pyramidalis causes congenital malformations and other reproductive losses in goats.
authors.affiliation: Setor de Patologia Veterinária, Universidade Federal do Recôncavo da Bahia, Rua Ruy Barbosa 710, Cruz das Almas, 44380-000, Bahia, Brazil.
authors.forename: Suélen Dias
authors.initials: SD
authors.lastname: Santos Dos Reis
authors.affiliation: Setor de Patologia Veterinária, Universidade Federal do Recôncavo da Bahia, Rua Ruy Barbosa 710, Cruz das Almas, 44380-000, Bahia, Brazil.
authors.forename: Ricardo Santana
authors.initials: RS
authors.lastname: de Oliveira
authors.affiliation: Setor de Patologia Veterinária, Universidade Federal do Recôncavo da Bahia, Rua Ruy Barbosa 710, Cruz das Almas, 44380-000, Bahia, Brazil.
authors.forename: Sóstenes Apolo
authors.initials: SA
authors.lastname: Correia Marcelino
authors.affiliation: Laboratório de Patologia Veterinária, Fundação Universidade de Brasília, Via L4 norte, 70910-970, Brasília, Distrito Federal, Brazil.
authors.forename: Juliana Targino
authors.initials: JT
authors.lastname: Silva Almeida E Macêdo
authors.affiliation: Veterinary Hospital, CSTR, Federal University of Campina Grande, Patos, 58700-310, Paraíba, Brazil; National Institute of Agricultural Research (INIA), Colonia del Sacramento, Colonia, Casilla de Correo 39173, CP 70.000, Uruguay.
authors.forename: Franklin
authors.initials: F
authors.lastname: Riet-Correa
authors.affiliation: Setor de Patologia Veterinária, Universidade Federal do Recôncavo da Bahia, Rua Ruy Barbosa 710, Cruz das Almas, 44380-000, Bahia, Brazil.
authors.forename: Luciano
authors.initials: L
authors.lastname: da Anunciação Pimentel
authors.affiliation: Laboratório de Patologia Veterinária, Fundação Universidade de Brasília, Via L4 norte, 70910-970, Brasília, Distrito Federal, Brazil. Electronic address: pedrosovet@yahoo.com.br.
authors.forename: Pedro Miguel
authors.initials: PM
authors.lastname: Ocampos Pedroso
mesh_terms: D000014:Abnormalities, Drug-Induced / Q000662:veterinary*; D000034:Abortion, Veterinary / Q000139:chemically induced*; D000818:Animals; D001176:Arthrogryposis / Q000139:chemically induced / Q000662:veterinary; D001938:Brazil; D029911:Caesalpinia / Q000633:toxicity*; D031744:Cynodon; D005260:Female; D005327:Fetal Resorption / Q000139:chemically induced / Q000662:veterinary*; D015511:Goat Diseases / Q000139:chemically induced* / Q000209:etiology* / Q000503:physiopathology; D006041:Goats; D008844:Micrognathism / Q000139:chemically induced / Q000662:veterinary; D035261:Plant Components, Aerial / Q000633:toxicity; D010939:Plant Poisoning / Q000503:physiopathology / Q000662:veterinary*; D011247:Pregnancy; D011248:Pregnancy Complications / Q000503:physiopathology / Q000662:veterinary*; D012600:Scoliosis / Q000139:chemically induced / Q000662:veterinary
keywords: Abortion; Embryonic death; Malformations; Small ruminants; Toxic plants