title: Effect of alpha1-blockers on stentless ureteroscopic lithotripsy.
abstract: OBJECTIVE
  To evaluate the clinical efficiency of alpha1-adrenergic antagonists on stentless ureteroscopic lithotripsy treating uncomplicated lower ureteral stones.
  
  
  METHODS
  From January 2007 to January 2013, 84 patients who have uncomplicated lower ureteral stones treated by ureteroscopic intracorporeal lithotripsy with the holmium laser were analyzed. The patients were divided into two groups, group A (44 patients received indwelled double-J stents) and group B (40 patients were treated by alpha1-adrenergic antagonists without stents). All cases of group B were treated with alpha1 blocker for 1 week.
  
  
  RESULTS
  The mean operative time of group A was significantly longer than group B. The incidences of hematuria, flank/abdominal pain, frequency/urgency after surgery were statistically different between both groups. The stone-free rate of each group was 100%.
  
  
  CONCLUSIONS
  The effect of alpha1-adrenergic antagonists is more significant than indwelling stent after ureteroscopic lithotripsy in treating uncomplicated lower ureteral stones.
authors.affiliation: Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
authors.forename: Jianguo
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
authors.forename: Yuxiang
authors.initials: Y
authors.lastname: Liang
authors.affiliation: Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
authors.forename: Weihong
authors.initials: W
authors.lastname: Chen
authors.affiliation: Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
authors.forename: Shuxiong
authors.initials: S
authors.lastname: Xu
authors.affiliation: Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
authors.forename: Yuanlin
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
authors.forename: Jianxing
authors.initials: J
authors.lastname: Hu
authors.affiliation: Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
authors.forename: Huichan
authors.initials: H
authors.lastname: He
authors.affiliation: Department of Urology, Guangdong Key Laboratory of Clinical Molecular Medicine and Diagnostics, Guangzhou First People's Hospital, Guangzhou Medical University, Guangzhou, China.
authors.forename: Wei-de
authors.initials: WD
authors.lastname: Zhong
authors.affiliation: Department of Urology, The People's Hospital of GuiZhou Provience, Guiyang, P.R. China.
authors.forename: Zhaolin
authors.initials: Z
authors.lastname: Sun
mesh_terms: D058668:Adrenergic alpha-1 Receptor Antagonists / Q000627:therapeutic use*; D000328:Adult; D005260:Female; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use; D007902:Length of Stay; D008096:Lithotripsy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D010147:Pain Measurement; D011183:Postoperative Complications; D011184:Postoperative Period; D011446:Prospective Studies; D015203:Reproducibility of Results; D018709:Statistics, Nonparametric; D013449:Sulfonamides / Q000627:therapeutic use*; D000077409:Tamsulosin; D016896:Treatment Outcome; D014514:Ureteral Calculi / Q000601:surgery*; D018666:Ureteroscopy / Q000379:methods*; D055815:Young Adult
chemical_list: D058668:Adrenergic alpha-1 Receptor Antagonists; D013449:Sulfonamides; D000077409:Tamsulosin