title: External Magnetic Field-Induced Targeted Delivery of Highly Sensitive Iron Oxide Nanocubes for MRI of Myocardial Infarction.
abstract: Magnetic field responsive nanocubes (MFRFs) are synthesized as nanoplatforms for external magnetic field-induced selective targeting of macrophages in the infarcted tissue and magnetic resonance imaging (MRI) monitoring. MFRFs have uniform size, favorable colloidal stability, and high magnetic properties. Under the influence of external magnetic field, MFRFs perform qualitative and quantitative MRI of myocardial infarction.
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
authors.forename: Bingbing
authors.initials: B
authors.lastname: Hu
authors.affiliation: Department of Radiology, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing, 100029, P. R. China.
authors.forename: Mu
authors.initials: M
authors.lastname: Zeng
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, P. R. China.
authors.forename: Jingli
authors.initials: J
authors.lastname: Chen
authors.affiliation: School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou, 450001, P. R. China.
authors.forename: Zhenzhong
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Collaborative Innovation Center for Biotherapy, School of Medicine, Tsinghua University, Beijing, 100084, P. R. China.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Radiology, Beijing An Zhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vessel Disease, Beijing, 100029, P. R. China. fanzm120@126.com.
authors.forename: Zhanming
authors.initials: Z
authors.lastname: Fan
authors.affiliation: National Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing, 100190, P. R. China. xzhang@ipe.ac.cn.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
mesh_terms: D000818:Animals; D016923:Cell Death / Q000187:drug effects; D005290:Ferric Compounds / Q000494:pharmacology*; D060526:Magnetic Fields; D008279:Magnetic Resonance Imaging; D051379:Mice; D009203:Myocardial Infarction / Q000175:diagnosis* / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D000067996:RAW 264.7 Cells; D051381:Rats; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D005290:Ferric Compounds; C000499:ferric oxide
keywords: external magnetic fields; iron oxide nanocubes; magnetic field responsive; magnetic resonance imaging; myocardial infarction