title: The Challenge of Clostridium difficile Infection.
abstract: Clostridium difficile infection is a major problem in the United States, resulting in significant morbidity, mortality, and financial costs to the health care system. This commentary provides an update regarding the epidemiology, diagnosis, current recommended management, and challenges surrounding C. difficile infection.
authors.affiliation: gastroenterology fellow, Gastroenterology Section, Department of Internal Medicine, Carolinas Medical Center, Charlotte, North Carolina.
authors.forename: David C
authors.initials: DC
authors.lastname: Olson
authors.affiliation: gastroenterology fellowship program director, Gastroenterology Section, Department of Internal Medicine, Carolinas Medical Center, Charlotte, North Carolina martin.scobey@carolinashealthcare.org.
authors.forename: Martin W
authors.initials: MW
authors.lastname: Scobey
mesh_terms: D016360:Clostridioides difficile; D004761:Enterocolitis, Pseudomembranous / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D000069467:Fecal Microbiota Transplantation; D006801:Humans; D012008:Recurrence