title: Diagnostic and therapeutic aspects in malignant sinonasal lymphoma.
abstract: Among head and neck malignancies, lymphoma is the second most frequent cause. They can develop in the head and neck lymph nodes or as extranodal determinations. The onset of malignant lymphoma outside of lymph node registers increasingly frequent, currently over 30% of malignant lymphoma are diagnosed as taking place outside the lymph nodes. The aim of this paper is bringing in discussion and the presentation of current elements on the diagnosis and treatment in case of malignant sinonasal lymphoma, a pathological entity with a growing incidence. This study is a retrospective one, from January 2008 through December 2013, and included 31 patients admitted to "Prof. Dr. Dorin Hociota" Institute of Phonoaudiology and Functional ENT (Ear, Nose & Throat) Surgery, Bucharest, Romania, and diagnosed with malignant sinonasal lymphoma. Despite progress in terms of immunological techniques, cytogenetic and molecular histological outlining of malignant lymphomas, correct diagnosis and appropriate therapy of malignant sinonasal lymphoma is still a problem for the clinician and pathologist, as multidisciplinary collaboration of ENT-Hematology-Pathology-Radiotherapy being essential in this regard.
authors.affiliation: "Prof. Dr. Dorin Hociota" Institute of Phonoaudiology and Functional ENT Surgery, Bucharest, Romania; mtusaliu@yahoo.com.
authors.forename: Mihail
authors.initials: M
authors.lastname: Tuşaliu
authors.forename: Viorel
authors.initials: V
authors.lastname: Zainea
authors.forename: Carmen Aurelia
authors.initials: CA
authors.lastname: Mogoantă
authors.forename: Ana Alexandra
authors.initials: AA
authors.lastname: Dragu
authors.forename: Cristina Maria
authors.initials: CM
authors.lastname: GoanŢă
authors.forename: Maria
authors.initials: M
authors.lastname: NiŢescu
authors.forename: Marina Ruxandra
authors.initials: MR
authors.lastname: OŢelea
authors.forename: Vlad Andrei
authors.initials: VA
authors.lastname: Budu
mesh_terms: D006801:Humans; D007150:Immunohistochemistry; D008223:Lymphoma / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D008444:Maxillary Sinus Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery / Q000628:therapy*; D009296:Nasal Cavity / Q000473:pathology / Q000601:surgery