title: Frequency of hemorrhagic complications on abdominal CT in patients with warfarin therapy.
abstract: OBJECTIVE
  To evaluate the frequency of hemorrhagic complications on abdominal computed tomography (CT) in patients with warfarin therapy and its correlation with intensity of anticoagulation.
  
  
  METHODS
  We included 646 patients who received warfarin therapy with international normalized ratio (INR) greater than 3.0 and abdominal CT within 1month after INR measurement.
  
  
  RESULTS
  Seventy-four patients (11.5%) showed hemorrhagic complications on abdominal CT. Frequency of hemorrhagic complications significantly correlated with intensity of anticoagulation (P<.001).
  
  
  CONCLUSIONS
  Hemorrhagic complications on abdominal CT in patients with warfarin therapy were not rare, and it occurred more frequently in patients with higher INR.
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Sunyoung
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea. Electronic address: dichoi@skku.edu.
authors.forename: Dongil
authors.initials: D
authors.lastname: Choi
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Woo Kyoung
authors.initials: WK
authors.lastname: Jeong
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Kyoung Doo
authors.initials: KD
authors.lastname: Song
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Min
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Ah Yeong
authors.initials: AY
authors.lastname: Kim
authors.affiliation: Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
authors.forename: Mimi
authors.initials: M
authors.lastname: Kim
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006470:Hemorrhage / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology*; D006801:Humans; D019934:International Normalized Ratio; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014859:Warfarin / Q000009:adverse effects* / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin
keywords: Abdominal CT; Hemorrhagic complications; International normalized ratio (INR); Warfarin therapy