title: Superb Microvascular Imaging-A new vascular detecting ultrasonographic technique for avascular breast masses: A preliminary study.
abstract: OBJECTIVE
  Superb Microvascular Imaging (SMI) is a new vascular imaging technique detecting a slower velocity that color Doppler flow image (CDFI) cannot. The aim of this study is to evaluate the clinical value of SMI for detecting penetrating vessels (PVs) in avascular breast lesions.
  
  
  METHODS
  Seventy-nine patients with 82 breast lesions were examined by conventional ultrasound and diagnosed as Breast Imaging Reporting and Data System (BI-RADS) level 3 or 4. CDFI detected no PVs; subsequently, Power Doppler (PD), Advanced Dynamic Flow (ADF), and SMI were performed to detect any PVs in the breast lesions.
  
  
  RESULTS
  Compared with PD or ADF, SMI revealed significantly (P<0.01) higher median numbers of PVs in breast lesions. The area under the receiver operating characteristic curve was 0.914 before the corrected classification versus 0.947 after the corrected classification (P<0.05).
  
  
  CONCLUSIONS
  SMI was helpful in the differential diagnosis of benign versus malignant in avascular breast lesions, especially those in BI-RADS category 4.
authors.affiliation: Department of Ultrasound Huadong Hospital, Fudan University, Shanghai, PR China. Electronic address: zhanjia@fudan.sh.
authors.forename: Jia
authors.initials: J
authors.lastname: Zhan
authors.affiliation: Department of Ultrasound Huadong Hospital, Fudan University, Shanghai, PR China. Electronic address: xuehong_d@126.com.
authors.forename: Xue-Hong
authors.initials: XH
authors.lastname: Diao
authors.affiliation: Department of Ultrasound Huadong Hospital, Fudan University, Shanghai, PR China. Electronic address: jimjin870531@163.com.
authors.forename: Jia-Mei
authors.initials: JM
authors.lastname: Jin
authors.affiliation: Department of Ultrasound Huadong Hospital, Fudan University, Shanghai, PR China. Electronic address: cl_point@126.com.
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Ultrasound Huadong Hospital, Fudan University, Shanghai, PR China. Electronic address: ultrasound_drchen@163.com.
authors.forename: Yue
authors.initials: Y
authors.lastname: Chen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001940:Breast / Q000098:blood supply / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000098:blood supply* / Q000000981:diagnostic imaging* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D055806:Microvessels / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012372:ROC Curve; D015203:Reproducibility of Results; D016217:Ultrasonography, Mammary / Q000379:methods*; D055815:Young Adult
keywords: BI-RADS 4; Breast masses; Penetrating vessel; Superb Microvascular Imaging; Ultrasonography; Vascular imaging