title: LassoProt: server to analyze biopolymers with lassos.
abstract: The LassoProt server, http://lassoprot.cent.uw.edu.pl/, enables analysis of biopolymers with entangled configurations called lassos. The server offers various ways of visualizing lasso configurations, as well as their time trajectories, with all the results and plots downloadable. Broad spectrum of applications makes LassoProt a useful tool for biologists, biophysicists, chemists, polymer physicists and mathematicians. The server and our methods have been validated on the whole PDB, and the results constitute the database of proteins with complex lassos, supported with basic biological data. This database can serve as a source of information about protein geometry and entanglement-function correlations, as a reference set in protein modeling, and for many other purposes.
authors.affiliation: University of Warsaw, Faculty of Chemistry, Pasteura 1, Warsaw, Poland Centre of New Technologies, University of Warsaw, Banacha 2c, Warsaw, Poland.
authors.forename: Pawel
authors.initials: P
authors.lastname: Dabrowski-Tumanski
authors.affiliation: Centre of New Technologies, University of Warsaw, Banacha 2c, Warsaw, Poland University of Silesia, Institute of Mathematics, Bankowa 14, Katowice, Poland.
authors.forename: Wanda
authors.initials: W
authors.lastname: Niemyska
authors.affiliation: Centre of New Technologies, University of Warsaw, Banacha 2c, Warsaw, Poland.
authors.forename: Pawel
authors.initials: P
authors.lastname: Pasznik
authors.affiliation: University of Warsaw, Faculty of Chemistry, Pasteura 1, Warsaw, Poland Centre of New Technologies, University of Warsaw, Banacha 2c, Warsaw, Poland jsulkowska@chem.uw.edu.pl.
authors.forename: Joanna I
authors.initials: JI
authors.lastname: Sulkowska
mesh_terms: D001704:Biopolymers / Q000737:chemistry*; D030562:Databases, Protein / Q000592:standards; D020407:Internet; D008958:Models, Molecular; D011506:Proteins / Q000737:chemistry* / Q000378:metabolism; D015203:Reproducibility of Results; D012984:Software / Q000592:standards
chemical_list: D001704:Biopolymers; D011506:Proteins