title: Temporary Single Ventricle Palliation for Severe Diastolic Dysfunction in a Biventricular Heart.
abstract: We describe a neonate with severe left ventricular (LV) dysfunction manifesting soon after birth, who required extracorporeal life support (ECLS). Multiple attempts at separation from ECLS resulted in high left atrial pressures and hemorrhagic pulmonary edema. The inability to separate from ECLS after ten days prompted an unconventional treatment strategy. We performed a modified Norwood operation for LV rehabilitation on day 10 of ECLS. This was followed by successful separation from ECLS. Left ventricular function recovered, and the child underwent conversion to a biventricular circulation on 128 days post-Norwood.
authors.affiliation: 1 Queensland Paediatric Cardiac Services, Lady Cilento Children's Hospital, Brisbane, Australia.|2 UQ School of Medicine, University of Queensland, Brisbane, Australia.|3 Mater Medical Research Institute, Brisbane, Australia.
authors.forename: Sudesh
authors.initials: S
authors.lastname: Prabhu
authors.affiliation: 1 Queensland Paediatric Cardiac Services, Lady Cilento Children's Hospital, Brisbane, Australia.|2 UQ School of Medicine, University of Queensland, Brisbane, Australia.
authors.forename: Tom
authors.initials: T
authors.lastname: Karl
authors.affiliation: 1 Queensland Paediatric Cardiac Services, Lady Cilento Children's Hospital, Brisbane, Australia.
authors.forename: Jim
authors.initials: J
authors.lastname: Morwood
authors.affiliation: 1 Queensland Paediatric Cardiac Services, Lady Cilento Children's Hospital, Brisbane, Australia.|2 UQ School of Medicine, University of Queensland, Brisbane, Australia.|3 Mater Medical Research Institute, Brisbane, Australia.
authors.forename: Nelson
authors.initials: N
authors.lastname: Alphonso
mesh_terms: D002648:Child; D003971:Diastole; D015199:Extracorporeal Membrane Oxygenation; D006330:Heart Defects, Congenital / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D006352:Heart Ventricles / Q000002:abnormalities* / Q000000981:diagnostic imaging / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D058327:Norwood Procedures / Q000379:methods*; D013902:Radiography, Thoracic; D012189:Retrospective Studies; D012720:Severity of Illness Index; D016277:Ventricular Function, Left / Q000502:physiology*
keywords: Norwood operation; single ventricle physiology; ventricular dysfunction