title: Anti-CCR5 Therapy Circumvents Immune Cell Exploitation by Tumors.
abstract: CCL5 produced by T cells at invasive margins of colorectal cancer metastases promotes tumor growth.
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D049109:Cell Proliferation / Q000187:drug effects; D018946:Chemokine CCL5 / Q000037:antagonists & inhibitors*; D016207:Cytokines / Q000378:metabolism; D006801:Humans; D008264:Macrophages / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D020782:Matrix Metalloproteinases / Q000378:metabolism; D058990:Molecular Targeted Therapy; D009369:Neoplasms / Q000188:drug therapy / Q000276:immunology* / Q000378:metabolism* / Q000473:pathology; D013601:T-Lymphocytes / Q000187:drug effects / Q000276:immunology / Q000378:metabolism; D059016:Tumor Microenvironment / Q000187:drug effects / Q000276:immunology
chemical_list: D000970:Antineoplastic Agents; D018946:Chemokine CCL5; D016207:Cytokines; D020782:Matrix Metalloproteinases