title: Medicinal Attributes of Imidazo[1,2-a]pyridine Derivatives: An Update.
abstract: The imidazo[1,2-a]pyridine scaffold is recognized as a privileged structure as it represents a promising area for identification of lead structures towards the discovery of new synthetic drug molecules. Several commercial drugs such as Zolpidem, Olprinone, Soraprazan and many other compounds in biological testing and preclinical evaluation, illustrate the wide therapeutic spectrum in this class of drug scaffolds. The present manuscript represents the assimilation of literature pertaining to medicinal aspects of this pharmacophore including the structure-activity relationships.
authors.forename: Nisha
authors.initials: N
authors.lastname: Devi
authors.forename: Dharmender
authors.initials: D
authors.lastname: Singh
authors.forename: Ravindra K
authors.initials: RK
authors.lastname: Rawal
authors.forename: Jitender
authors.initials: J
authors.lastname: Bariwal
authors.affiliation: Department of Chemistry, Dr B R Ambedkar National Institute of Technology, Jalandhar 144011, India. singhv@nitj.ac.in.
authors.forename: Virender
authors.initials: V
authors.lastname: Singh
mesh_terms: D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology; D004247:DNA / Q000187:drug effects; D007093:Imidazoles / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000890:Anti-Infective Agents; D007093:Imidazoles; D011725:Pyridines; D004247:DNA