title: In vitro fertilization outcomes in obese women under and above 35 years of age.
abstract: OBJECTIVE
  To explore the impact of obesity on in vitro fertilization (IVF) outcomes and comparing the results with regards to age groups.
  
  
  METHODS
  This retrospective cohort recruited 780 women that underwent IVF. Women with polycystic ovarian syndrome (PCOS) were excluded from the study. Women under and above 35 years were categorized into three groups as normal weight, overweight, and obese. The main outcome measures were ovarian response, oocyte maturity, and clinical pregnancy rates.
  
  
  RESULTS
  Despite oocyte count and fertilization rate that decreased in both younger and older obese women, this difference was not statistically significant. After age matched-normal weight controls, the clinical pregnancy rates were significantly decreased in older obese women. On the other hand, poor ovarian response observed significantly in young obese women without effect on pregnancy rates.
  
  
  CONCLUSIONS
  These results suggested that obesity in young and old women has different outcomes and different steps of IVF process may be affected.
authors.forename: F
authors.initials: F
authors.lastname: Vural
authors.forename: B
authors.initials: B
authors.lastname: Vural
authors.forename: Y
authors.initials: Y
authors.lastname: Çakiroglu
mesh_terms: D000328:Adult; D005260:Female; D005306:Fertilization; D005307:Fertilization in Vitro / Q000379:methods; D006801:Humans; D007246:Infertility / Q000150:complications / Q000628:therapy*; D008423:Maternal Age; D009765:Obesity / Q000150:complications*; D009865:Oocytes; D050177:Overweight / Q000150:complications; D010062:Ovulation Induction / Q000379:methods*; D011085:Polycystic Ovary Syndrome / Q000150:complications*; D011247:Pregnancy; D018873:Pregnancy Rate; D012189:Retrospective Studies