title: Usefulness of basic renal function tests in decision-making in children with loss of renal parenchyma and/or dilation of the urinary tract.
abstract: Basic renal function tests such as maximum urine osmolality and urinary elimination of albumin and N-acetyl-glucosaminidase often reveal abnormalities in clinical cases involving hyperpressure in the urinary tract or loss of renal parenchyma. However, in all the available algorithms dedicated to the study of children with urinary tract infection or dilation, the benefit of using these functional parameters is not mentioned. In this review, we provide information about the practical usefulness of assessing the basic renal function parameters. From these data, we propose an algorithm that combines morphological and functional parameters to make a reasoned case for voiding cystourethrography.
authors.affiliation: Sección de Nefrología Pediátrica, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España. Electronic address: vgarcianieto@gmail.com.
authors.forename: Víctor M
authors.initials: VM
authors.lastname: García Nieto
authors.affiliation: Sección de Nefrología Pediátrica, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Maria Isabel
authors.initials: MI
authors.lastname: Luis Yanes
authors.affiliation: Sección de Nefrología Pediátrica, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, España.
authors.forename: Pedro
authors.initials: P
authors.lastname: Arango Sancho
authors.affiliation: Servicio de Pediatría, Mälarsjukhuset, Eskilstuna, Suecia.
authors.forename: Jorge V
authors.initials: JV
authors.lastname: Sotoca Fernandez
mesh_terms: D000465:Algorithms; D002648:Child; D000066491:Clinical Decision-Making; D003950:Diagnostic Techniques, Urological; D004108:Dilatation, Pathologic / Q000175:diagnosis / Q000503:physiopathology; D049672:History, 19th Century; D049673:History, 20th Century; D006801:Humans; D007668:Kidney / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000473:pathology*; D007671:Kidney Concentrating Ability; D007677:Kidney Function Tests / Q000266:history; D009994:Osmolar Concentration; D016482:Urinalysis; D014551:Urinary Tract / Q000002:abnormalities / Q000000981:diagnostic imaging / Q000473:pathology*; D014552:Urinary Tract Infections / Q000150:complications; D014572:Urology / Q000266:history / Q000379:methods; D014718:Vesico-Ureteral Reflux / Q000175:diagnosis / Q000209:etiology
keywords: Albuminuria; Capacidad de concentración; Cistografía; Concentrating capacity; Cystourethrography; N-acetil-glucosaminidasa; N-acetyl-glucosaminidase; Reflujo vesicoureteral; Vesicoureteral reflux