title: [Clinical analysis of two cases of imported children Zika virus infection in China].
abstract: OBJECTIVE
  To analyze the clinical characteristics, outcome and diagnosis of two cases of imported children Zika virus infection in China.
  
  
  METHODS
  A retrospective analysis was performed on clinical characteristics, treatment and outcome of two cases of imported children with Zika virus infection in February 2016 in Enping People's Hospital of Guangdong.
  
  
  RESULTS
  Two cases of children with imported Zika virus infection resided in an affected area of Venezuela, 8-year-old girl and her 6 year-old brother. The main findings on physical examination included the following manifestations: fever, rash, and conjunctivitis. The rash was first limited to the abdomen, but extended to the torso, neck and face, and faded after 3-4 d. The total number of white blood cells was not high and liver function was normal. The diagnosis of two cases of Zika virus infection was confirmed by the expert group of Guangdong Provincial Center for Disease Control and Prevention, according to the epidemiological history, clinical manifestations and Zika virus nucleic acid detection results.Treatment of Zika virus infection involves supportive care. Two Zika virus infection children had a relatively benign outcome.
  
  
  CONCLUSIONS
  At present, Zika virus infection in children is an imported disease in China. No specific therapy is available for this disease. Information on long-term outcomes among infants and children with Zika virus disease is limited, routine pediatric care is advised for these infants and children.
authors.affiliation: Department of Infectious Diseases, Enping People's Hospital of Gunagdong, Enping 529400, China.
authors.forename: C G
authors.initials: CG
authors.lastname: Zheng
authors.affiliation: Department of Infectious Diseases, Guangzhou Women and Children's Medical Center, Guangzhou 510120, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Xu
authors.forename: H Q
authors.initials: HQ
authors.lastname: Jiang
authors.forename: Y X
authors.initials: YX
authors.lastname: Yin
authors.forename: J H
authors.initials: JH
authors.lastname: Zhang
authors.forename: W J
authors.initials: WJ
authors.lastname: Zhu
authors.forename: X J
authors.initials: XJ
authors.lastname: Liang
authors.forename: M X
authors.initials: MX
authors.lastname: Chen
authors.forename: J W
authors.initials: JW
authors.lastname: Ye
authors.forename: L M
authors.initials: LM
authors.lastname: Tan
authors.forename: D
authors.initials: D
authors.lastname: Luo
authors.forename: S T
authors.initials: ST
authors.lastname: Gong
mesh_terms: D002648:Child; D002681:China; D005076:Exanthema; D005260:Female; D005334:Fever; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D014687:Venezuela; D000071244:Zika Virus / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000175:diagnosis*