title: Lichen planus-like drug reaction associated with recombinant human growth hormone therapy in a child patient with Turner syndrome.
abstract: Turner syndrome (TS) is a genetic disease with an incidence rate of between 1:2000 and 1:5000 live female births. The treatment of TS differs according to age and Recombinant Human Growth Hormone (RHGH) therapy is usually given for the treatment of short stature in girls with TS in childhood. We describe the first case of a TS patient who presented with a clinical picture compatible with oral and palmoplantar lichen planus-like reaction during RHGH therapy; spontaneous remission occurred after therapy suspension.
authors.affiliation: University of São Paulo. Mariana_soares_@hotmail.com.
authors.forename: Mariana Quirino Silveira
authors.initials: MQ
authors.lastname: Soares
authors.forename: Elismauro Fancisco
authors.initials: EF
authors.lastname: Mendonca
mesh_terms: D002648:Child; D003875:Drug Eruptions / Q000209:etiology*; D005260:Female; D005533:Foot Dermatoses / Q000139:chemically induced*; D006229:Hand Dermatoses / Q000139:chemically induced*; D019382:Human Growth Hormone / Q000009:adverse effects*; D006801:Humans; D008010:Lichen Planus / Q000139:chemically induced*; D009061:Mouth Mucosa / Q000473:pathology; D011994:Recombinant Proteins / Q000009:adverse effects*; D013280:Stomatitis / Q000139:chemically induced* / Q000473:pathology; D014424:Turner Syndrome / Q000188:drug therapy*
chemical_list: D011994:Recombinant Proteins; D019382:Human Growth Hormone