title: Actin Dynamics and HIV-1 Entry.
abstract: Cortical F-actin plays important roles during HIV-1 infection. A recent paper in Cell highlights the involvement of F-actin in enhancing dendritic cell (DC)-mediated HIV-1 infection of T cells. Such a critical mechanism of HIV-1 trans-enhancement between human DCs and T cells had not been analyzed in molecular detail before this work.
authors.affiliation: Division of Structural Biology, University of Oxford, The Henry Wellcome Building for Genomic Medicine, Headington, Oxford OX3 7BN, UK; Wellcome Trust Human Genetics, Cellular Imaging Core, University of Oxford, Oxford, UK. Electronic address: spadilla@well.ox.ac.uk.
authors.forename: Sergi
authors.initials: S
authors.lastname: Padilla-Parra
authors.affiliation: The Kennedy Institute of Rheumatology, University of Oxford, Headington, Oxford OX3 7BN, UK. Electronic address: michael.dustin@kennedy.ox.ac.uk.
authors.forename: Michael L
authors.initials: ML
authors.lastname: Dustin