title: Sulfasalazine: A rare cause of acute eosinophilic pneumonia.
abstract: Sulfasalazine is a compound of 5-aminosalicylic acid (5-ASA) and sulfapyridine joined by an azo bond. It is a widely used drug in the treatment of chronic inflammatory bowel disease. Fatal toxicity of sulfasalazine arises from its effects on the bone marrow and the resulting blood dyscrasias. Pulmonary toxicity from sulfasalazine is a rather rare finding. Here, we present the case of a patient who developed acute eosinophilic pneumonia with sulfasalazine use.
authors.affiliation: Department of Respiratory Medicine, St. Vincent's University Hospital, Dublin, Ireland.
authors.forename: P
authors.initials: P
authors.lastname: Nadarajan
authors.affiliation: Department of Histopathology, St. Vincent's University Hospital, Dublin, Ireland.
authors.forename: A
authors.initials: A
authors.lastname: Fabre
authors.affiliation: Department of Respiratory Medicine, St. Vincent's University Hospital, Dublin, Ireland.
authors.forename: E
authors.initials: E
authors.lastname: Kelly
keywords: ASA, Aminosalicylic Acid; BAL, Bronchoalveolar Lavage; CRP, C-reactive protein; Drug induced lung disease; Eosinophilic pneumonia; Interstitial lung disease; MGG, May-Grunwald-Giemsa; TNF-α, Tumour necrosis factor alpha