title: [Update on post-stroke depression: posing new challenges in patients with a minor stroke or transient ischaemic attack].
abstract: BACKGROUND
  Stroke is a leading cause of disability in adults. The development of depressive symptoms is the most common emotional complication. To date, most studies of post-stroke depression have excluded patients who have suffered a minor stroke or transient ischaemic attack (TIA), although they are equally vulnerable subgroups of this sickness.
  
  
  OBJECTIVE
  We present a review of published studies of post-stroke depression to elucidate aspects that have already been widely demonstrated and those who need more evidence.
  
  
  METHODS
  The post-stroke depression is both frequent in patients with established stroke and minor stroke or TIA. Although there are discrepancies in the definition used, in up to one out of three patients will develop this complication. We have identified risk factors of post-stroke depression with a broad scientific background (female, history of depression or other psychiatric disorders, stroke severity, functional impairment) and other without it (quality of life, cognitive impairment and neuroimaging biomarkers). The main methodological limitations found are: confusion between post-stroke depression and depressive symptoms; variability in rating scales used; and temporal variability in the time of the evaluation of mood. To date very few studies focused on minor stroke or TIA.
  
  
  CONCLUSIONS
  Further studies are required with improved design in order to help establish the risk of post-stroke depression at different times after the stroke, minor stroke or TIA and the importance of all the factors described above.
authors.affiliation: Universitat de Lleida, 25198 Lleida, Espana.
authors.forename: A
authors.initials: A
authors.lastname: Carnes-Vendrell
authors.affiliation: Universitat Autonoma de Barcelona, Bellaterra, Espana.|CRC-Mar Hospital del Mar, Barcelona, Espana.
authors.forename: J
authors.initials: J
authors.lastname: Deus-Yela
authors.affiliation: Universitat de Lleida, 25198 Lleida, Espana.|Hospital Arnau de Vilanova, Valencia, Espana.
authors.forename: J
authors.initials: J
authors.lastname: Molina-Seguin
authors.affiliation: Universitat de Lleida, 25198 Lleida, Espana.
authors.forename: J
authors.initials: J
authors.lastname: Pifarre-Paredero
authors.affiliation: Hospital Universitari Arnau de Vilanova, 25006 Lleida, Espana.|Universitat de Lleida, 25198 Lleida, Espana.
authors.forename: F
authors.initials: F
authors.lastname: Purroy
mesh_terms: D003863:Depression / Q000209:etiology*; D006801:Humans; D002546:Ischemic Attack, Transient / Q000150:complications*; D011788:Quality of Life; D012307:Risk Factors; D020521:Stroke / Q000150:complications*