title: [Primary hyperaldosteronism due to unilateral adrenal hyperplasia with surgical resolution].
abstract: Unilateral adrenal hyperplasia is a rare cause of primary hyperaldosteronism (around a 3%) that has surgical treatment. A case of a patient with hypertension resistant to conventional therapy in treatment with 7 drugs who presented with primary hyperaldosteronism due to unilateral adrenal hyperplasia is presented. A left adrenalectomy was performed, and the patient had a good clinical response, with no need of any drug after 2 years of surgery. Unilateral adrenal hyperplasia is a different entity and it is not an asymmetric variant of the bilateral adrenal hyperplasia. In the study of patients with primary hyperaldosteronism and imaging tests with absence of adenoma is a diagnosis that must be considered before cataloguing patients with bilateral adrenal hyperplasia and start a medical treatment, because unilateral adrenal hyperplasia would have a surgical resolution.
authors.affiliation: Servicio de Endocrinología y Nutrición, Hospital General Universitario de Castellón, Castellón, España. Electronic address: olallarubio@gmail.com.
authors.forename: O
authors.initials: O
authors.lastname: Rubio-Puchol
authors.affiliation: Servicio de Endocrinología y Nutrición, Hospital Universitario Doctor Peset, Valencia, España.
authors.forename: S
authors.initials: S
authors.lastname: Garzón-Pastor
authors.affiliation: Servicio de Endocrinología y Nutrición, Hospital Universitario Doctor Peset, Valencia, España.
authors.forename: C
authors.initials: C
authors.lastname: Salom-Vendrell
authors.affiliation: Servicio de Endocrinología y Nutrición, Hospital Universitario Doctor Peset, Valencia, España; Departamento de Medicina, Universidad de Valencia, Valencia, España; Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO), Valencia, España.
authors.forename: A
authors.initials: A
authors.lastname: Hernández-Mijares
mesh_terms: D000311:Adrenal Glands / Q000000981:diagnostic imaging / Q000473:pathology*; D000315:Adrenalectomy; D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D006929:Hyperaldosteronism / Q000209:etiology*; D006965:Hyperplasia / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery; D006973:Hypertension / Q000188:drug therapy / Q000601:surgery*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D014057:Tomography, X-Ray Computed; D028761:Withholding Treatment
chemical_list: D000959:Antihypertensive Agents
keywords: Adrenal hyperplasia; Hiperaldosteronismo; Hiperplasia adrenal; Hipertensión resistente; Hyperaldosteronism; Hypertension resistant to conventional therapy