title: Leg Rejuvenation: A Combination Approach: A Review and Our Experience.
abstract: BACKGROUND
  Patients increasingly seek to enhance the appearance of their legs. Elimination of unwanted leg veins, reduction of epidermal photo-aging changes such as solar lentigines and keratoses, tightening of skin laxity and reduction of adipose tissue are among the most commonly requested goals. Many patients require a combination approach to address their concerns. It is important for dermatologists to be aware of the multitude of procedures that can be performed, often in combination, to rejuvenate the leg.
  
  
  OBJECTIVE
  The purpose of this review article was to discuss procedures for improving the appearance of the leg and to share the authors experience, especially in the combination approach to leg rejuvenation.
  
  
  METHODS
  A literature search was performed to investigate cosmetic procedures being performed on the leg, with an emphasis on controlled or randomized studies. In addition, the authors contributed their personal experience.
  
  
  RESULTS
  Our discussion of the literature review highlights the treatments for leg veins, unwanted fat, cellulite, and photodamage of the legs that are most supported in peer-reviewed publications.
  
  
  CONCLUSIONS
  A synergistic, combination approach to leg rejuvenation works best. This includes the use of injectable agents, energy-based devices, and more invasive surgical procedures.
authors.affiliation: *Maryland Laser, Skin and Vein Institute, Hunt Valley, Maryland; †Gold Skin Care Center, Nashville, Tennessee; ‡Division of Dermatology, Section of Procedural Dermatology, Cooper University Health Care, Marlton, New Jersey.
authors.forename: Margaret
authors.initials: M
authors.lastname: Weiss
authors.forename: Anne M
authors.initials: AM
authors.lastname: Mahoney
authors.forename: Michael
authors.initials: M
authors.lastname: Gold
authors.forename: Naomi
authors.initials: N
authors.lastname: Lawrence
mesh_terms: D000071697:Cellulite / Q000628:therapy; D003131:Combined Modality Therapy; D057086:High-Intensity Focused Ultrasound Ablation; D006801:Humans; D053685:Laser Therapy; D007866:Leg; D015187:Lipectomy; D000078702:Radiofrequency Therapy; D012060:Rejuvenation; D015911:Sclerotherapy; D015595:Skin Aging; D014648:Varicose Veins / Q000628:therapy*