title: MicroRNA therapeutics: Discovering novel targets and developing specific therapy.
abstract: MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression in diverse biological process. They act as intracellular mediators that are necessary for various biological processes. MicroRNAs targeting pathways of human disease provide a new and potential powerful candidate for therapeutic intervention against various pathological conditions. Even though, the information about miRNA biology has significantly enriched but we still do not completely understand the mechanism of miRNA gene regulation. Various groups across the globe and pharmaceutical companies are conducting research and developments to explore miRNA based therapy and build a whole new area of miroRNA therapeutics. Consequently, few miRNAs have entered the preclinical and clinical stage and soon might be available in the market for use in humans.
authors.affiliation: Division of Clinical Research, University Centre of Excellence in Research, Baba Farid University of Health Science, Faridkot, Punjab, India.
authors.forename: Ajay Francis
authors.initials: AF
authors.lastname: Christopher
authors.affiliation: Division of Clinical Research, University Centre of Excellence in Research, Baba Farid University of Health Science, Faridkot, Punjab, India.
authors.forename: Raman Preet
authors.initials: RP
authors.lastname: Kaur
authors.affiliation: Division of Clinical Research, University Centre of Excellence in Research, Baba Farid University of Health Science, Faridkot, Punjab, India.
authors.forename: Gunpreet
authors.initials: G
authors.lastname: Kaur
authors.affiliation: Division of Clinical Research, University Centre of Excellence in Research, Baba Farid University of Health Science, Faridkot, Punjab, India.
authors.forename: Amandeep
authors.initials: A
authors.lastname: Kaur
authors.affiliation: Division of Clinical Research, University Centre of Excellence in Research, Baba Farid University of Health Science, Faridkot, Punjab, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Gupta
authors.affiliation: Division of Clinical Research, University Centre of Excellence in Research, Baba Farid University of Health Science, Faridkot, Punjab, India.
authors.forename: Parveen
authors.initials: P
authors.lastname: Bansal
keywords: Clinical stage; gene expression; microRNA; therapeutics