title: Ameloblastic Fibrosarcoma of the mandible evolving from a prior Ameloblastic Fibroma after two years: an unusual finding.
abstract: Transformation of an ameloblastic fibroma to an ameloblastic fibrosarcoma has been reported rarely in the literature. The present case report describes such evolution in a patient under long-term follow-up. The patient was first treated in 2008, and he developed the malignant counterpart of the disease 2 years later. The patient is currently under careful long-term follow-up and is free of disease. This article describes the clinical and radiographic features, histological characteristics, immunohistochemical findings, and surgical treatment of the tumor.
authors.affiliation: University of Bologna, Bologna, Italy.
authors.forename: Franco
authors.initials: F
authors.lastname: Bertoni
authors.affiliation: University of Bologna, Bologna, Italy giacomo.delcorso@unibo.it.
authors.forename: Giacomo
authors.initials: G
authors.lastname: Del Corso
authors.affiliation: Villa Erbosa Hospital, Bologna, Italy.
authors.forename: Patrizia
authors.initials: P
authors.lastname: Bacchini
authors.affiliation: University of Bologna, Bologna, Italy.
authors.forename: Claudio
authors.initials: C
authors.lastname: Marchetti
authors.affiliation: University of Bologna, Bologna, Italy.
authors.forename: Achille
authors.initials: A
authors.lastname: Tarsitano
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D002471:Cell Transformation, Neoplastic; D018450:Disease Progression; D005350:Fibroma / Q000175:diagnosis / Q000473:pathology*; D005354:Fibrosarcoma / Q000175:diagnosis / Q000473:pathology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000473:pathology*; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis / Q000473:pathology; D009808:Odontogenic Tumors / Q000175:diagnosis / Q000473:pathology*
chemical_list: D014408:Biomarkers, Tumor
keywords: ameloblastic fibroma; ameloblastic fibrosarcoma