title: A method for determining arsenolipids in seawater by HPLC-high resolution mass spectrometry.
abstract: Arsenic-containing lipids (arsenolipids), naturally occurring arsenicals in algae, have never been detected in seawater even though they might be introduced to the water column on senescence of marine algae or by active excretion. The complex nature of seawater presents an analytical challenge to detect these compounds and to monitor their environmental fate. We developed a simple sample preparation method using liquid-liquid extraction combined with HPLC-high resolution mass spectrometry (HRMS) capable of measuring six standard arsenolipids in seawater at the ng As/L level (<1% of the total arsenic in seawater). The method is suitable for studies on the biotransformation and pathways of arsenolipids in the marine environment. When we applied the method to four samples of natural seawater, however, we did not find any of the six standard arsenolipids.
authors.affiliation: Institute of Chemistry-Analytical Chemistry, NAWI Graz, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria.
authors.forename: Muslim
authors.initials: M
authors.lastname: Khan
authors.affiliation: Institute of Chemistry-Analytical Chemistry, NAWI Graz, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria.
authors.forename: Kenneth B
authors.initials: KB
authors.lastname: Jensen
authors.affiliation: Institute of Chemistry-Analytical Chemistry, NAWI Graz, University of Graz, Universitaetsplatz 1, 8010 Graz, Austria. Electronic address: kevin.francesconi@uni-graz.at.
authors.forename: Kevin A
authors.initials: KA
authors.lastname: Francesconi
mesh_terms: D001151:Arsenic; D001152:Arsenicals; D002851:Chromatography, High Pressure Liquid; D008055:Lipids; D013058:Mass Spectrometry; D012623:Seawater / Q000737:chemistry*
chemical_list: D001152:Arsenicals; D008055:Lipids; D001151:Arsenic
keywords: Arsenolipids; Mass spectrometry; Seawater