title: Even Noisy Responses Can Be Perfect If Integrated Properly.
abstract: Integral feedback for perfect adaptation is a ubiquitous strategy in engineering and biology. Long studied in deterministic settings, it can now be understood in the context of the fully stochastic systems that are prevalent in biology.
authors.affiliation: Computing and Mathematical Sciences, Electrical Engineering, and Bioengineering, California Institute of Technology, Pasadena, CA 91125, USA. Electronic address: doyle@caltech.edu.
authors.forename: John C
authors.initials: JC
authors.lastname: Doyle
mesh_terms: D000222:Adaptation, Physiological; D004738:Engineering; D005246:Feedback; D008954:Models, Biological; D013269:Stochastic Processes; D049490:Systems Biology