title: A new pattern of lipomatosis of nerve: case report.
abstract: Lipomatosis of nerve (LN) is a rare disorder of peripheral nerves that produces proliferation of interfascicular adipose tissue. It may be associated with soft-tissue and bony overgrowth within the affected nerve territory. LN has been almost exclusively reported in appendicular peripheral nerves; the median nerve at the wrist and palm is among the most common locations. The authors present a new pattern of LN that shows circumferential proliferation of fat around the epineurium of the nerve. They believe that this case and the two other documented examples in the literature (also affecting cervical and thoracic spinal nerves) share the same new pattern of LN. Defining the full spectrum of adipose lesions of the nerve and establishing a cause-effect relationship with nerve-territory overgrowth disorders may offer options for future management through targeted nerve lesioning.
authors.affiliation: Departments of 1 Neurologic Surgery and.
authors.forename: Nikhil K
authors.initials: NK
authors.lastname: Prasad
authors.affiliation: Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Mahan
authors.affiliation: Radiology, Mayo Clinic, Rochester, Minnesota; and.
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Howe
authors.affiliation: Radiology, Mayo Clinic, Rochester, Minnesota; and.
authors.forename: Kimberly K
authors.initials: KK
authors.lastname: Amrami
authors.affiliation: Departments of 1 Neurologic Surgery and.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Spinner
mesh_terms: D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008067:Lipoma / Q000175:diagnosis* / Q000601:surgery; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000601:surgery; D064170:Paraspinal Muscles; D010524:Peripheral Nervous System Neoplasms / Q000175:diagnosis* / Q000601:surgery; D013127:Spinal Nerves; D013904:Thoracic Vertebrae; D055815:Young Adult
keywords: LN = lipomatosis of nerve; MDL = macrodystrophia lipomatosa; lipomatosis of nerve; osseous hypertrophy; peripheral nerve; segmental overgrowth