title: Comparison of Oral Function: Free Anterolateral Thigh Perforator Flaps Versus Vascularized Free Forearm Flap for Reconstruction in Patients Undergoing Glossectomy.
abstract: OBJECTIVE
  This study evaluated oral function in patients with tongue cancer who underwent immediate free flap reconstruction surgery. In addition, the efficacy of the anterolateral thigh perforator free flap (ALTFF) and the radial free forearm flap (RFFF) for reconstruction was compared in patients with glossectomy.
  
  
  METHODS
  Sixty-seven patients undergoing complete or partial glossectomy and reconstruction with free flaps were grouped according to flap type (ALTFF vs RFFF). Oral functions were assessed using the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire Head and Neck Module, the University of Washington Quality of Life, and the 14-item Oral Health Impact Profile questionnaires at 6 and 12 months after reconstructive surgery.
  
  
  RESULTS
  Sixty-seven of 80 questionnaires (83.75%) were returned. There were significant differences between the 2 groups concerning the style of resection (P < .005). For all oral function domains, the score improved progressively after the operation (6 and 12 months after the procedure). There were no meaningful differences between the 2 flap types for all oral function domains at 12 months.
  
  
  CONCLUSIONS
  Using the RFFF or ALTFF for reconstruction of tongue defects after cancer resection meaningfully influences oral function. Free flap reconstruction of the tongue is the most critical factor in achieving a successful functional result.
authors.affiliation: Researcher, Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Yuan
authors.affiliation: Resident, Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
authors.forename: Peipei
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Professor, Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
authors.forename: Wei
authors.initials: W
authors.lastname: He
authors.affiliation: Researcher, Department of Stomatology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China. Electronic address: lwldoctor@163.com.
authors.forename: Wenlu
authors.initials: W
authors.lastname: Li
mesh_terms: D004185:Disability Evaluation; D005260:Female; D005542:Forearm / Q000601:surgery; D058752:Free Tissue Flaps / Q000098:blood supply*; D005927:Glossectomy / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D061525:Perforator Flap / Q000098:blood supply*; D011788:Quality of Life; D020127:Recovery of Function; D011795:Surveys and Questionnaires; D013848:Thigh / Q000601:surgery; D014062:Tongue Neoplasms / Q000601:surgery*; D016896:Treatment Outcome