title: SERS monitoring the dynamics of local pH in lysosome of living cells during photothermal therapy.
abstract: In this communication, we propose a gold nanorod-based SERS nanotracker to monitor the local pH change during photothermal therapy (PTT). The dynamic SERS analysis indicated that the local pH of the lysosome in living cells increased during the PTT which would be helpful to understand the cellular metabolic processes and further facilitate the photosensitizer screening and optimization.
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn.
authors.forename: Rongxing
authors.initials: R
authors.lastname: Luo
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn.
authors.forename: Yinhui
authors.initials: Y
authors.lastname: Li
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn.
authors.forename: Qifeng
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn.
authors.forename: Jing
authors.initials: J
authors.lastname: Zheng
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn.
authors.forename: Dandan
authors.initials: D
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn.
authors.forename: Pinting
authors.initials: P
authors.lastname: Tang
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410004, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Yang
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410004, China.
authors.forename: Zhihe
authors.initials: Z
authors.lastname: Qing
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, 410082, China. zhengjing2013@hnu.edu.cn Yangrh@pku.ed.cn and School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410004, China.
authors.forename: Ronghua
authors.initials: R
authors.lastname: Yang
mesh_terms: D006046:Gold; D006367:HeLa Cells; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008247:Lysosomes / Q000737:chemistry*; D043942:Nanotubes; D017319:Photosensitizing Agents / Q000494:pharmacology*
chemical_list: D017319:Photosensitizing Agents; D006046:Gold