title: [The Current Role of Salvage-Surgery of Recurrent Tumors in the Larynx and Pharynx].
abstract: Over the past 20 years, the therapeutic concepts for the treatment of head and neck cancer have evolved and non-surgical treatment strategies have gained in importance. However, despite improved organ preservation protocols and primary chemoradiation, tumor recurrence is still frequent. Under these conditions, salvage surgery if often the only remaining curative treatment option. Over the past 30 years, advancements in plastic-reconstructive surgery have broadened the surgical spectrum in the head and neck area, offering new treatment options for salvage surgery in recurrent cancer of the pharynx and larynx. Survival after salvage surgery mainly depends on the primary treatment modality as well as the localization and tumor stage at the time of initial diagnosis and local recurrence. For the reconstruction of defects after salvage surgery, pedicled flaps and microvascular free flaps may be utilized. The most frequently used flaps in these situations are the pectoralis major island- or the myocutaneous latissimus dorsi island flap. The radial forearm and the ALT-flap are potentially applicable free flaps. With the use of these flaps, vital tissue is transferred into the previously irradiated area, hereby allowing for reconstruction and functional preservation of the resected area and preventing complications such as fistulas. The expected morbidity and the likelihood of surgical success must be assessed thoroughly in every individual case prior to performing salvage surgery. This review aims to support decision making in these situations.
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Universitätsklinikum Essen, Universität Duisburg-Essen.
authors.forename: B A
authors.initials: BA
authors.lastname: Stuck
authors.affiliation: HNO-Gemeinschaftspraxis, Gelsenkirchen.
authors.forename: N
authors.initials: N
authors.lastname: Rothmeier
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Universitätsklinikum Essen, Universität Duisburg-Essen.
authors.forename: S
authors.initials: S
authors.lastname: Mattheis
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Universitätsklinikum Essen, Universität Duisburg-Essen.
authors.forename: N
authors.initials: N
authors.lastname: Dominas
authors.affiliation: Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie, Universitätsklinikum Essen, Universität Duisburg-Essen.
authors.forename: S
authors.initials: S
authors.lastname: Lang
mesh_terms: D058752:Free Tissue Flaps / Q000098:blood supply* / Q000601:surgery*; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008866:Microsurgery / Q000379:methods*; D009364:Neoplasm Recurrence, Local / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D009959:Oropharyngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery; D010610:Pharyngeal Neoplasms / Q000401:mortality / Q000473:pathology* / Q000601:surgery*; D016879:Salvage Therapy / Q000379:methods* / Q000401:mortality; D013524:Surgical Flaps / Q000601:surgery*