title: Network Meta-analysis to Synthesize Evidence for Decision Making in Cardiovascular Research.
abstract: Clinical decision-making requires synthesis of evidence from literature reviews focused on a specific theme. Evidence synthesis is performed with qualitative assessments and systematic reviews of randomized clinical trials, typically covering statistical pooling with pairwise meta-analyses. These methods include adjusted indirect comparison meta-analysis, network meta-analysis, and mixed-treatment comparison. These tools allow synthesis of evidence and comparison of effectiveness in cardiovascular research.
authors.affiliation: Departmento de Pesquisa Clínica, Universidade Federal de Uberlândia, Uberlândia, MG, Brazil.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Roever
authors.affiliation: Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Biondi-Zoccai
mesh_terms: D035843:Biomedical Research; D002318:Cardiovascular Diseases; D000066491:Clinical Decision-Making / Q000379:methods*; D002986:Clinical Trials as Topic; D057186:Comparative Effectiveness Research; D019317:Evidence-Based Medicine / Q000379:methods*; D006801:Humans; D000071076:Network Meta-Analysis as Topic; D012107:Research Design; D012196:Review Literature as Topic