title: Flipping the Rac-Rho Switch in Cell Motility.
abstract: Mutual inhibition of Rac and Rho GTPases leads to bistability and hysteresis at both the biochemical and cell behavior levels.
authors.affiliation: Department of Mathematics, University of British Columbia, Vancouver, BC V6T 1Z2, Canada. Electronic address: keshet@math.ubc.ca.
authors.forename: Leah
authors.initials: L
authors.lastname: Edelstein-Keshet
mesh_terms: D002465:Cell Movement; D020744:rac GTP-Binding Proteins; D020830:rac1 GTP-Binding Protein; D020741:rho GTP-Binding Proteins
chemical_list: D020744:rac GTP-Binding Proteins; D020830:rac1 GTP-Binding Protein; D020741:rho GTP-Binding Proteins