title: Sleep duration and quality, and risk of gestational diabetes mellitus in pregnant Chinese women.
abstract: To examine the association between sleep disturbances during pregnancy and risk of gestational diabetes mellitus.
  
  
  
  From 2010 to 2012, 12 506 women in Tianjin, China, were screened using a 50-g 1-h glucose challenge test at 24-28 weeks' gestation. Those with glucose challenge test values of ≥ 7.8 mmol/l were invited to further undergo a 75-g 2-h oral glucose tolerance test. Gestational diabetes was determined according to the International Association of Diabetes and Pregnancy Study Group's definition. Self-reported sleep duration and sleep quality during pregnancy was documented using a modified questionnaire. Logistic regression was used to obtain odds ratios and 95% CIs.
  
  
  
  A total of 919 women (7.3%) had gestational diabetes. Sleep duration was found to have an approximate J-shaped association with gestational diabetes risk after adjusting for covariates. Compared with a sleep duration of 7-9 h/day (43% of 12 506 women), the adjusted odds ratios for sleep duration of ≥ 9 h/day (55%) and < 7 h/day (2%) for gestational diabetes were 1.21 (95% CI 1.03-1.42) and 1.36 (95% CI 0.87-2.14), respectively. Compared with good sleep quality (37.9% of 12 506 women), the adjusted odds ratios of moderate (59.9%) and poor sleep quality (2.2%) for gestational diabetes were 1.19 (95% CI 1.01-1.41) and 1.61 (95% CI 1.04-2.50), respectively.
  
  
  
  In pregnant Chinese women, poor sleep quality, and shorter and longer duration of sleep during pregnancy were independently associated with an increased risk of gestational diabetes.
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.|Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: J
authors.initials: J
authors.lastname: Leng
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: W
authors.initials: W
authors.lastname: Li
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: L
authors.initials: L
authors.lastname: Wang
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: C
authors.initials: C
authors.lastname: Zhang
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: W
authors.initials: W
authors.lastname: Li
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: H
authors.initials: H
authors.lastname: Liu
authors.affiliation: Tianjin Women and Children's Health Centre, Tianjin, China.
authors.forename: S
authors.initials: S
authors.lastname: Zhang
authors.affiliation: Department of Medicine and Therapeutics, Hong Kong Institute of Diabetes and Obesity and Li Ka Shing Institute of Health Science, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China.
authors.forename: J
authors.initials: J
authors.lastname: Chan
authors.affiliation: Chronic Disease Epidemiology Laboratory, Pennington Biomedical Research Center, Baton Rouge, LA, USA.
authors.forename: G
authors.initials: G
authors.lastname: Hu
authors.affiliation: Population Cancer Research Program and Department of Pediatrics, Dalhousie University, Halifax, Canada.
authors.forename: Z
authors.initials: Z
authors.lastname: Yu
authors.affiliation: Department of Epidemiology and Biostatistics, School of Public Health, Tianjin Medical University, Tianjin, China.
authors.forename: X
authors.initials: X
authors.lastname: Yang
mesh_terms: D044466:Asian People; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D016640:Diabetes, Gestational / Q000175:diagnosis / Q000453:epidemiology / Q000208:ethnology / Q000209:etiology*; D006970:Disorders of Excessive Somnolence / Q000097:blood / Q000208:ethnology / Q000503:physiopathology*; D005260:Female; D005951:Glucose Tolerance Test; D006801:Humans; D007231:Infant, Newborn; D016015:Logistic Models; D011247:Pregnancy; D011248:Pregnancy Complications / Q000097:blood / Q000208:ethnology / Q000503:physiopathology*; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis; D011446:Prospective Studies; D011788:Quality of Life; D012307:Risk Factors; D057566:Self Report; D012892:Sleep Deprivation / Q000097:blood / Q000208:ethnology / Q000503:physiopathology*