title: Effectiveness of Three Desensitizing Dentifrices on Cervical Dentin Hypersensitivity: A Pilot Clinical Trial.
abstract: OBJECTIVE
  Cervical dentin hypersensitivity (CDH) is defined as an acute pain of short duration that occurs in dentin exposed to the oral environment. The aim of this study was to evaluate the effi cacy of three desensitizing toothpastes (Sensodyne® Rapid-Relief, Colgate® Sensitive Pro-Relief, Nano P®) for immediate and intermediate-term relief of CDH, when compared with a control toothpaste (Cocoricó®).
  
  
  METHODS
  Eight patients were enrolled in this clinical study. One hundred thirty-eight hypersensitive teeth were randomized into four groups according to the com- position of the desensitizing toothpaste tested: Group I) strontium acetate and calcium carbonate; II) calcium carbonate and arginine 8%; III) calcium phosphate nanoparticles; and IV) a control toothpaste. A split mouth design was used for one application each of the desensitizing dentifrices. Assessment of CDH was done by evaporative and cold stimuli at baseline, immediately, 24 hours and 30 days after the treatment.
  
  
  RESULTS
  The toothpastes presented similar effectiveness and statistically significant improvement in 30 days compared to baseline. Group III showed statistically significant relief for cervical dentin hypersensitivity immediately after the treatment.
  
  
  CONCLUSIONS
  The only toothpaste that presented immediate relief effect was the paste containing calcium phosphate nanoparticles in the form of hydroxyapatite.
authors.affiliation: Department of Periodontology, Dentistry School, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. dhodonto@hotmail.com.br.
authors.forename: Dhelfeson Willya
authors.initials: DW
authors.lastname: Douglas de Oliveira
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: Evandro Silveira de
authors.initials: ES
authors.lastname: Oliveira
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: André Felipe Miranda
authors.initials: AF
authors.lastname: Mota
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: Victor Hugo Urzedo
authors.initials: VH
authors.lastname: Pereira
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: Vinícius Oliveira
authors.initials: VO
authors.lastname: Bastos
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: José Cristiano Ramos
authors.initials: JC
authors.lastname: Glória
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: Patricia Furtado
authors.initials: PF
authors.lastname: Gonçalves
authors.affiliation: Department of Dentistry, Federal University of Jequitinhonha and Mucuri Valleys, Diamantina, MG, Brazil.
authors.forename: Olga Dumont
authors.initials: OD
authors.lastname: Flecha
keywords: clinical trial; dentin sensitivity; pain; toothpaste