title: A real-world evidence study evaluating a treatment for nappy rash.
abstract: This retrospective open study evaluating the efficacy of Sudocrem Antiseptic Healing Cream (SAHC) in infantile nappy rash (NR) was based on real-world evidence collected using an online questionnaire that included Likert scales. Participants who had used SAHC in the past (n=2159) were recruited via social media and email. A total of 1818 respondents who had treated NR in the previous 6 months were asked to take part in the study. Over 50% of respondents saw an improvement in NR on the same day that treatment was started, and within 3 days 94.5% of respondents reported an improvement in NR. Of 1804 subjects who answered the question, 72.5% indicated that the NR had completely healed within 3 days of starting treatment and by the fifth day, 94.7% said that the NR had completely healed. A total of 71% of 1793 respondents said that an episode of NR had either no or minimal impact disrupting their normal lives, but 29% reported a noticeable impact, even though evidence suggests that mild to moderate nappy rash can be treated quickly. Based on this real-world retrospective study, the evidence suggests SAHC is rapidly effective, reduces signs and symptoms of inflammation, and heals NR.
authors.affiliation: Chief Medical Officer, Iatros Consulting, London.
authors.forename: Martin
authors.initials: M
authors.lastname: Goldman
authors.affiliation: Medical Director, Allergan Limited, Marlow.
authors.forename: Imran
authors.initials: I
authors.lastname: Lodhi
mesh_terms: D000779:Anesthetics, Local / Q000627:therapeutic use*; D000891:Anti-Infective Agents, Local / Q000627:therapeutic use*; D001565:Benzoates / Q000627:therapeutic use; D019905:Benzyl Alcohol / Q000627:therapeutic use; D001593:Benzyl Compounds / Q000627:therapeutic use; D002675:Child, Preschool; D002934:Cinnamates / Q000627:therapeutic use; D003879:Dermatologic Agents / Q000627:therapeutic use; D003963:Diaper Rash / Q000188:drug therapy*; D004487:Edema; D004643:Emollients / Q000627:therapeutic use*; D004890:Erythema; D005260:Female; D006358:Hot Temperature; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007249:Inflammation; D007809:Lanolin / Q000627:therapeutic use; D008297:Male; D010146:Pain; D012189:Retrospective Studies; D063465:Skin Cream / Q000627:therapeutic use*; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D014945:Wound Healing; D015034:Zinc Oxide / Q000627:therapeutic use
chemical_list: D000779:Anesthetics, Local; D000891:Anti-Infective Agents, Local; D001565:Benzoates; D001593:Benzyl Compounds; D002934:Cinnamates; D003879:Dermatologic Agents; D004643:Emollients; D007809:Lanolin; D019905:Benzyl Alcohol; C006723:benzyl benzoate; D015034:Zinc Oxide; C526327:benzyl cinnamate
keywords: Dermatitis; Inflammation; Nappy rash; Real-world evidence