title: Contrast-enhanced continuous-terahertz-wave imaging based on superparamagnetic iron oxide nanoparticles for biomedical applications.
abstract: We present a novel contrast-enhanced continuous-terahertz-wave imaging modality based on magnetic induction heating of superparamagnetic iron oxide nanoparticles (SPIOs), which yields a highly sensitive increment in the reflection terahertz (THz) signal in SPIO solution upon exposure to an alternating magnetic field. In the differential and relative refection change focal-plane images before and after alternating magnetic field exposure, a dramatic contrast is demonstrated between water with and without SPIOs. This low-cost, simple, and stable contrast-enhanced continuous-THz-wave imaging system is suitable for miniaturization and real-time imaging application.
authors.forename: Rui
authors.initials: R
authors.lastname: Zhang
authors.forename: Liangliang
authors.initials: L
authors.lastname: Zhang
authors.forename: Tong
authors.initials: T
authors.lastname: Wu
authors.forename: Shasha
authors.initials: S
authors.lastname: Zuo
authors.forename: Ruixue
authors.initials: R
authors.lastname: Wang
authors.forename: Cunlin
authors.initials: C
authors.lastname: Zhang
authors.forename: Jue
authors.initials: J
authors.lastname: Zhang
authors.forename: Jing
authors.initials: J
authors.lastname: Fang
mesh_terms: D005290:Ferric Compounds / Q000737:chemistry*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry*; D055069:Terahertz Imaging / Q000379:methods*
chemical_list: D005290:Ferric Compounds; D058185:Magnetite Nanoparticles; C000499:ferric oxide