title: A divergent synthetic approach to diverse molecular scaffolds: assessment of lead-likeness using LLAMA, an open-access computational tool.
abstract: Complementary cyclisation reactions of hex-2-ene-1,6-diamine derivatives were exploited in the synthesis of alternative molecular scaffolds. The value of the synthetic approach was analysed using LLAMA, an open-access computational tool for assessing the lead-likeness and novelty of molecular scaffolds.
authors.affiliation: School of Chemistry, University of Leeds, Leeds, LS2 9JT, UK. s.p.marsden@leeds.ac.uk a.s.nelson@leeds.ac.uk.
authors.forename: Ignacio
authors.initials: I
authors.lastname: Colomer
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Empson
authors.forename: Philip
authors.initials: P
authors.lastname: Craven
authors.forename: Zachary
authors.initials: Z
authors.lastname: Owen
authors.forename: Richard G
authors.initials: RG
authors.lastname: Doveston
authors.forename: Ian
authors.initials: I
authors.lastname: Churcher
authors.forename: Stephen P
authors.initials: SP
authors.lastname: Marsden
authors.forename: Adam
authors.initials: A
authors.lastname: Nelson