title: Gab2 is essential for Bcr-Abl-mediated leukemic transformation and hydronephrosis in a chronic myeloid leukemia mouse model.
authors.affiliation: Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, University of Freiburg, Freiburg, Germany.|Faculty of Biology, University of Freiburg, Freiburg, Germany.|Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Halbach
authors.affiliation: Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, University of Freiburg, Freiburg, Germany.|Faculty of Biology, University of Freiburg, Freiburg, Germany.|Spemann Graduate School of Biology and Medicine, University of Freiburg, Freiburg, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Köhler
authors.affiliation: Faculty of Biology, University of Freiburg, Freiburg, Germany.|Department of Medicine I, Hematology, Oncology and Stem-Cell Transplantation, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
authors.forename: F M
authors.initials: FM
authors.lastname: Uhl
authors.affiliation: Center for Pathology, Institute of Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.|Comprehensive Cancer Center Freiburg CCCF, Medical Center-University of Freiburg, Freiburg, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Huber
authors.affiliation: Department of Medicine I, Hematology, Oncology and Stem-Cell Transplantation, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.|Comprehensive Cancer Center Freiburg CCCF, Medical Center-University of Freiburg, Freiburg, Germany.|Centre for Biological Signalling Studies BIOSS, University of Freiburg, Freiburg, Germany.|Deutsches Konsortium für Translationale Krebsforschung (DKTK), Standort Freiburg, Freiburg, Germany.
authors.forename: R
authors.initials: R
authors.lastname: Zeiser
authors.affiliation: Department of Hematology, Oncology, Hemostaseology and Stem Cell Transplantation, Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Koschmieder
authors.affiliation: Center for Pathology, Institute of Surgical Pathology, Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
authors.forename: K
authors.initials: K
authors.lastname: Aumann
authors.affiliation: Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, University of Freiburg, Freiburg, Germany.|Comprehensive Cancer Center Freiburg CCCF, Medical Center-University of Freiburg, Freiburg, Germany.|Centre for Biological Signalling Studies BIOSS, University of Freiburg, Freiburg, Germany.|Deutsches Konsortium für Translationale Krebsforschung (DKTK), Standort Freiburg, Freiburg, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Brummer
mesh_terms: D048868:Adaptor Proteins, Signal Transducing; D000818:Animals; D002471:Cell Transformation, Neoplastic / Q000235:genetics*; D004195:Disease Models, Animal; D016044:Fusion Proteins, bcr-abl / Q000235:genetics; D006869:Hydronephrosis / Q000209:etiology; D015464:Leukemia, Myelogenous, Chronic, BCR-ABL Positive / Q000235:genetics / Q000378:metabolism* / Q000473:pathology*; D051379:Mice; D008822:Mice, Transgenic; D010750:Phosphoproteins / Q000378:metabolism*
chemical_list: D048868:Adaptor Proteins, Signal Transducing; C490894:Gab2 protein, mouse; D010750:Phosphoproteins; D016044:Fusion Proteins, bcr-abl