title: Pathology analysis of a rare case of diffuse pulmonary lymphangiomatosis.
abstract: Diffuse pulmonary lymphangiomatosis (DPL) is a rare lymphatic disorder characterized by uncontrolled proliferation of lymphatic vessels. Histologically benign, however, it can lead to death because of its progression. In this paper, we would like to present an unusual case of diffuse pulmonary lymphangiomatosis involving a 28-year-old young female who was suffered chest pain and polypnea for one year, and also a lot of chylous effusion in left chest. Lymphoma and lymphangitic metastasis was the primary diagnosis in other hospitals. However, histologic sections of pleural biopsy revealed diffuse pleural lymphatic proliferation characteristic of DPL, wherein the histologic findings can be subtle and could be overlooked as nonspecific reactive changes or misdiagnosed as an idiopathic interstitial lung disease. Recognition of the characteristic lymphangitic distribution of abnormally dilated or reduplicated lymphatic spaces is the key to the correct diagnosis.
authors.affiliation: The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease (Guangzhou Medical University, China), Guangzhou Institute of Respiratory disease, Guangzhou 510120, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Zhao
authors.affiliation: The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease (Guangzhou Medical University, China), Guangzhou Institute of Respiratory disease, Guangzhou 510120, China.
authors.forename: Ruibin
authors.initials: R
authors.lastname: Wu
authors.affiliation: The First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease (Guangzhou Medical University, China), Guangzhou Institute of Respiratory disease, Guangzhou 510120, China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Gu
keywords: Diffuse pulmonary lymphangiomatosis (DPL); diagnosis; pathology analysis