title: Three-dimensional models of cochlear implants: A review of their development and how they could support management and maintenance of cochlear implant performance.
abstract: Three-dimensional (3D) computational modeling of the auditory periphery forms an integral part of modern-day research in cochlear implants (CIs). These models consist of a volume conduction description of implanted stimulation electrodes and the current distribution around these, coupled with auditory nerve fiber models. Cochlear neural activation patterns can then be predicted for a given input stimulus. The objective of this article is to present the context of 3D modeling within the field of CIs, the different models, and approaches to models that have been developed over the years, as well as the applications and potential applications of these models. The process of development of 3D models is discussed, and the article places specific emphasis on the complementary roles of generic models and user-specific models, as the latter is important for translation of these models into clinical application.
authors.affiliation: a Bioengineering, Department of Electrical, Electronic and Computer Engineering , University of Pretoria , Pretoria , South Africa.
authors.forename: Tania
authors.initials: T
authors.lastname: Hanekom
authors.affiliation: a Bioengineering, Department of Electrical, Electronic and Computer Engineering , University of Pretoria , Pretoria , South Africa.
authors.forename: Johan J
authors.initials: JJ
authors.lastname: Hanekom
mesh_terms: D019929:Cochlear Implantation; D003054:Cochlear Implants; D003056:Cochlear Nerve; D004567:Electrodes, Implanted; D008962:Models, Theoretical
keywords: 3D cochlear modeling; neural model; user-specific models; volume conduction model