title: Association between parathyroid hormone levels and the extensiveness of coronary artery disease.
abstract: Previous studies have suggested that there is a relationship between coronary artery disease (CAD) and parathyroid hormone (PTH) levels. Here, we aimed to evaluate the association between PTH levels and severity of CAD.
  
  
  
  Patients were divided into two groups based on their serum PTH values. Patients with PTH levels ≤72 pg/mL were accepted as Group 1 (n=568) and >72 pg/mL as Group 2 (n=87). Gensini score system and >50% stenosis in any coronary artery with conventional coronary angiography were used to determine the extensiveness of CAD. This study was designed as a prospective and cross-sectional study.
  
  
  
  Baseline characteristics except for age, gender, and blood pressure were similar between groups. Mean serum PTH levels of the entire cohort was 43.4±29.5 pg/mL. Median Gensini score was 19.5 in Group 1 and 14.5 in Group 2 (p=0.75). On the other hand, PTH levels were weakly correlated with Gensini score (Spearman's Rho=0.11, p=0.003). Additionally, we did not observe a statistically significant difference between PTH levels and the number of stenotic vessels (p=0.14). This study was designed as a prospective and cross-sectional study.
  
  
  
  There is no association between serum PTH levels and extensiveness of CAD.
authors.affiliation: Department of Cardiology, Atatürk Education and Research Hospital, Ankara-Turkey. dryakupalsancak@gmail.com.
authors.forename: Yakup
authors.initials: Y
authors.lastname: Alsancak
authors.affiliation: Department of Cardiology, Numune Education and Research Hospital, Ankara-Turkey.
authors.forename: Emrullah
authors.initials: E
authors.lastname: Kızıltunç
authors.affiliation: Department of Cardiology, Gazi Mustafa Kemal State Hospital, Ankara-Turkey.
authors.forename: Burak
authors.initials: B
authors.lastname: Sezenöz
authors.affiliation: Department of Cardiology, 29 Mayıs State Hospital, Ankara-Turkey.
authors.forename: Selçuk
authors.initials: S
authors.lastname: Özkan
authors.affiliation: Department of Family Medicine, Numune Education and Research Hospital, Ankara-Turkey.
authors.forename: Aybüke
authors.initials: A
authors.lastname: Demir Alsancak
authors.affiliation: Department of Cardiology, Erciş State Hospital, Van-Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Gül
authors.affiliation: Department of Cardiology, Faculty of Medicine, Gazi University, Ankara-Turkey.
authors.forename: Atiye
authors.initials: A
authors.lastname: Çengel
mesh_terms: D015415:Biomarkers; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000097:blood*; D003430:Cross-Sectional Studies; D006801:Humans; D010281:Parathyroid Hormone / Q000097:blood*; D011446:Prospective Studies; D012307:Risk Factors; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers; D010281:Parathyroid Hormone