title: Gastrointestinal Complications in Patients Who Undergo Radical Cystectomy with Enhanced Recovery Protocol.
abstract: Gastrointestinal (GI) complications are among the most common complications following radical cystectomy and urinary diversion. The most common is postoperative ileus, although its precise pathophysiology is not completely understood. Enhanced recovery after surgery (ERAS) protocols include evidence-based steps to optimize postoperative recovery and shorten hospital stay, mainly through expedited GI function recovery. They include avoiding bowel preparation and postoperative nasogastric tube, early feeding, non-narcotic pain management, and the use of cholinergic and mu-receptor opioid antagonists. We reviewed the literature in regard to GI complications using enhanced recovery protocols and share our institutional experience with over 300 patients.
authors.affiliation: Institute of Urology, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Suite 7416, 90089, Los Angeles, CA, USA.
authors.forename: Hooman
authors.initials: H
authors.lastname: Djaladat
authors.affiliation: Institute of Urology, Norris Comprehensive Cancer Center, University of Southern California, 1441 Eastlake Avenue, Suite 7416, 90089, Los Angeles, CA, USA. daneshma@med.usc.edu.
authors.forename: Siamak
authors.initials: S
authors.lastname: Daneshmand
mesh_terms: D002985:Clinical Protocols; D003248:Constipation / Q000209:etiology / Q000517:prevention & control; D015653:Cystectomy / Q000009:adverse effects*; D003967:Diarrhea / Q000209:etiology / Q000517:prevention & control; D006801:Humans; D045823:Ileus / Q000209:etiology / Q000517:prevention & control; D009325:Nausea / Q000209:etiology / Q000517:prevention & control; D011182:Postoperative Care; D011183:Postoperative Complications; D014547:Urinary Diversion / Q000009:adverse effects*; D014839:Vomiting / Q000209:etiology / Q000517:prevention & control
keywords: Bladder cancer; Complications; Cystectomy; Enhanced recovery; Gastrointestinal