title: Evaluation of antimicrobial efficacy of cetrimide and Glycyrrhiza glabra L. extract against Enterococcus faecalis biofilm grown on dentin discs in comparison with NaOCl.
abstract: This study aimed to determine the antimicrobial efficacy of NaOCl, cetrimide, and Glycyrrhiza glabra L. extract against Enterococcus faecalis biofilms on dentine discs. Broth microdilution method was used to determine minimal bactericidal concentrations (MBCs) of the agents. A biofilm susceptibility assay was performed using E. faecalis biofilms grown on dentine discs. Minimal bactericidal concentrations (MBCs) of NaOCl (0.5%), cetrimide (0.015%), and G. glabra L. extract (0.25%) were applied for 1, 3, and 5 min, and the mean viable cell counts were recorded and statistically analyzed. There was no significant difference between cetrimide and NaOCl at 1 min (p>0.05). NaOCl was the most effective agent at 3 and 5 min (p<0.05) while G. glabra L. extract was the least (p<0.05). The MBCs of NaOCl, cetrimide, and G. glabra that eliminated the planktonic E. faecalis did not eradicate the biofilms grown on dentin discs.
authors.affiliation: Faculty of Dentistry, Department of Endodontics, University of Süleyman Demirel.
authors.forename: Hilmi Egemen
authors.initials: HE
authors.lastname: Güldas
authors.forename: Ayse Diljin
authors.initials: AD
authors.lastname: Kececi
authors.forename: Emel Sesli
authors.initials: ES
authors.lastname: Cetin
authors.forename: Tuba
authors.initials: T
authors.lastname: Ozturk
authors.forename: Bulem Üreyen
authors.initials: BÜ
authors.lastname: Kaya
mesh_terms: D000890:Anti-Infective Agents; D018441:Biofilms; D002593:Cetrimonium Compounds; D003804:Dentin; D013293:Enterococcus faecalis; D006035:Glycyrrhiza
chemical_list: D000890:Anti-Infective Agents; D002593:Cetrimonium Compounds