title: e23D: database and visualization of A-to-I RNA editing sites mapped to 3D protein structures.
abstract: e23D, a database of A-to-I RNA editing sites from human, mouse and fly mapped to evolutionary related protein 3D structures, is presented. Genomic coordinates of A-to-I RNA editing sites are converted to protein coordinates and mapped onto 3D structures from PDB or theoretical models from ModBase. e23D allows visualization of the protein structure, modeling of recoding events and orientation of the editing with respect to nearby genomic functional sites from databases of disease causing mutations and genomic polymorphism.
  
  
  
  http://www.sheba-cancer.org.il/e23D CONTACT: oz.solomon@live.biu.ac.il or Eran.Eyal@sheba.health.gov.il.
authors.affiliation: Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
authors.forename: Oz
authors.initials: O
authors.lastname: Solomon
authors.affiliation: Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel.
authors.forename: Eran
authors.initials: E
authors.lastname: Eyal
authors.affiliation: Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
authors.forename: Ninette
authors.initials: N
authors.lastname: Amariglio
authors.affiliation: The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
authors.forename: Ron
authors.initials: R
authors.lastname: Unger
authors.affiliation: Cancer Research Center, Sheba Medical Center, Ramat-Gan, Israel Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Gidi
authors.initials: G
authors.lastname: Rechavi
mesh_terms: D000818:Animals; D030562:Databases, Protein; D004330:Drosophila; D023281:Genomics; D006801:Humans; D051379:Mice; D017434:Protein Structure, Tertiary; D011506:Proteins / Q000737:chemistry*; D017393:RNA Editing; D012984:Software
chemical_list: D011506:Proteins