title: The effect of maraviroc on the pharmacokinetics of digoxin in healthy volunteers.
authors.affiliation: Pfizer Global Research and Development, New York, NY, USA.
authors.forename: Manoli
authors.initials: M
authors.lastname: Vourvahis
authors.affiliation: Pfizer Global Research and Development, Groton, CT, USA.
authors.forename: Juanzhi
authors.initials: J
authors.lastname: Fang
authors.affiliation: Pfizer Clinical Research Unit, Singapore, Singapore.
authors.forename: Heng Wee
authors.initials: HW
authors.lastname: Choo
authors.affiliation: Pfizer Global Research and Development, Groton, CT, USA.
authors.forename: Jayvant
authors.initials: J
authors.lastname: Heera
mesh_terms: D018435:ATP Binding Cassette Transporter, Subfamily B / Q000037:antagonists & inhibitors; D000328:Adult; D001682:Biological Availability; D065100:CCR5 Receptor Antagonists / Q000008:administration & dosage* / Q000494:pharmacology; D018592:Cross-Over Studies; D003510:Cyclohexanes / Q000008:administration & dosage* / Q000494:pharmacology; D004077:Digoxin / Q000008:administration & dosage / Q000493:pharmacokinetics*; D004305:Dose-Response Relationship, Drug; D004347:Drug Interactions; D004791:Enzyme Inhibitors / Q000008:administration & dosage / Q000493:pharmacokinetics*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D000077592:Maraviroc; D008875:Middle Aged; D014230:Triazoles / Q000008:administration & dosage* / Q000494:pharmacology; D055815:Young Adult
chemical_list: C513055:ABCB1 protein, human; D018435:ATP Binding Cassette Transporter, Subfamily B; D065100:CCR5 Receptor Antagonists; D003510:Cyclohexanes; D004791:Enzyme Inhibitors; D014230:Triazoles; D004077:Digoxin; D000077592:Maraviroc
keywords: CCR5 antagonist; P-glycoprotein; digoxin; maraviroc; pharmacokinetics