title: [Assessment of Cachexia in Head and Neck Cancer Patients Based on a Modified Glasgow Prognostic Score].
abstract: We retrospectively analyzed 54 patients who died of head and neck squamous cell caricinoma regarding the process and duration of cachexia using the modified Glasgow Prognostic Score (mGPS). The patients were classified as having cachexia when the serum albumin level was less than 3.5 mg/dL and the C-reactive protein (CRP) level was more than 0.5 mg/dL. The number of patients with cachexia was eight (8%) at the first visit and 50 (93%) at the time of death. In the 50 patients, the median and average time of having cachexia was 59 and 95 days, respectively. Thirty-two of the 50 patients (64%) died within three months after the presence of cachexia was confirmed. In this study, the time of having cachexia was so short, then the policy of care should be converted from aggressive into supportive in patients classified as having cachexia. mGPS would be an accurate assessment tool for cachexia and ascertain the end stage of head and neck cancer patients.
authors.forename: Takashi
authors.initials: T
authors.lastname: Matsuzuka
authors.forename: Masahiro
authors.initials: M
authors.lastname: Suzuki
authors.forename: Satoshi
authors.initials: S
authors.lastname: Saijoh
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ikeda
authors.forename: Mitsumasa
authors.initials: M
authors.lastname: Imaizumi
authors.forename: Yukio
authors.initials: Y
authors.lastname: Nomoto
authors.forename: Takamichi
authors.initials: T
authors.lastname: Matsui
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Tada
authors.forename: Koichi
authors.initials: K
authors.lastname: Omori
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D014408:Biomarkers, Tumor / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis; D002100:Cachexia / Q000209:etiology* / Q000628:therapy; D005260:Female; D023261:Glasgow Outcome Scale; D006258:Head and Neck Neoplasms / Q000737:chemistry / Q000150:complications* / Q000473:pathology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D010166:Palliative Care; D011379:Prognosis; D012189:Retrospective Studies; D013727:Terminal Care; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; D002097:C-Reactive Protein