title: Ultrasound Elastography for Distinction Between Parathyroid Adenomas and Thyroid Nodules.
abstract: OBJECTIVE
  The aim of this study was to detect the level of stiffness of parathyroid adenomas and to distinguish them from benign and malignant thyroid nodules using ultrasound elastography with acoustic radiation force impulse imaging.
  
  
  METHODS
  Twenty-one patients with parathyroid adenomas and 71 patients with thyroid nodules were evaluated by acoustic radiation force impulse imaging in this study. Acoustic radiation force impulse elastograms were obtained after evaluation of the thyroid nodules, which were predicted to undergo fine-needle aspiration biopsy, and patients with a diagnosis of hyperparathyroidism, which was identified by sonography at the same time.
  
  
  RESULTS
  An analysis of mean shear wave velocity (SWV) values for parathyroid adenomas and thyroid nodules showed that parathyroid adenomas had significantly higher stiffness levels compared to benign thyroid nodules (mean SWV ± SD, 3.09 ± 0.75 versus 2.20 ± 0.39 m/s; P < .001) and lower stiffness levels compared to malignant thyroid nodules (mean SWV, 3.09 ± 0.75 versus 3.59 ± 0.43 m/s; P < .001).
  
  
  CONCLUSIONS
  Acoustic radiation force impulse imaging has high sensitivity and specificity for differentiating parathyroid adenomas from benign and malignant thyroid nodules. As an adjunctive tool, it can help distinguish parathyroid adenomas from thyroid nodules, including posteriorly located nodules.
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey baturabdussamet@gmail.com.
authors.forename: Abdussamet
authors.initials: A
authors.lastname: Batur
authors.affiliation: Department of Endocrinology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Atmaca
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Yavuz
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Mesut
authors.initials: M
authors.lastname: Ozgokce
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Aydın
authors.initials: A
authors.lastname: Bora
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Mehmet Deniz
authors.initials: MD
authors.lastname: Bulut
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Arslan
authors.affiliation: Department of General Surgery, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Toktas
authors.affiliation: Department of Radiology, Yuzuncuyil University, Dursun Odabas Medical Center, Van, Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Alpaslan
mesh_terms: D000236:Adenoma / Q000000981:diagnostic imaging*; D003937:Diagnosis, Differential; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010280:Parathyroid Glands / Q000000981:diagnostic imaging; D010282:Parathyroid Neoplasms / Q000000981:diagnostic imaging*; D012372:ROC Curve; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016606:Thyroid Nodule / Q000000981:diagnostic imaging*
keywords: acoustic radiation force impulse imaging; head and neck ultrasound; parathyroid adenoma; thyroid nodules