title: Targeted Treatment in Childhood Epilepsy Syndromes.
abstract: The mainstay of treatment of epilepsy has been antiepileptic drugs; however, despite the emergence of new agents, a consistent proportion remain drug-resistant. Newer AEDs show promise. However, as it becomes clear that the epilepsies are a group of diseases rather than a single disorder the prospect of targeted treatment in some may become a reality.
authors.affiliation: Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK.
authors.forename: Katharina
authors.initials: K
authors.lastname: Vezyroglou
authors.affiliation: Clinical Neurosciences, 30 Guilford St, London, WC1N 1EH, UK. h.cross@ucl.ac.uk.|Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London, WC1N 3JH, UK. h.cross@ucl.ac.uk.
authors.forename: J Helen
authors.initials: JH
authors.lastname: Cross
keywords: Antiepileptic drugs (AED); Cannabidiol (CBD); Childhood epilepsies; Epileptic encephalopathy; Ketogenic diet (KD); Next generation sequencing (NGS); Targeted therapy