title: Acid Neutralization Capacity of a Tricalcium Silicate-Containing Calcium Phosphate Cement as an Endodontic Material.
abstract: A calcium phosphate cement (CPC) was shown to have the necessary attributes for endodontic materials except adequate basicity needed for antimicrobial properties. To enhance its basicity, tricalcium silicate (Ca3SiO5), a highly alkaline compound, was added to CPC at a mass fraction of 0.25, 0.5 or 0.75. The basicity, acid neutralization and physical properties of the CPC-Ca3SiO5 composites were investigated. Mineral trioxide aggregate (MTA) was used as the control. The acid neutralizing capacity of the CPC-Ca3SiO5 composites and MTA were measured by titrating the suspensions of ground set samples with a 0.2 mol / L HCl at predetermined pH levels, i.e., 11, 9.0, and 7.4. The setting time of CPC-Ca3SiO5 composites determined by the Gilmore needle method was 40 ± 10 min. Acid neutralizing capacity of CPC depended (p < 0.05) on Ca3SiO5 content. CPC containing 75 % Ca3SiO5 could neutralize slightly less acid than MTA (p < 0.05), but it had a shorter setting time than that of MTA (> 4 h) and excellent handling properties.
authors.affiliation: American Dental Association Foundation, Paffenbarger Research Center, MML, National Institute of Standards and Technology, Gaithersburg, MD 20899.
authors.forename: A Maria
authors.initials: AM
authors.lastname: Cherng
authors.affiliation: American Dental Association Foundation, Paffenbarger Research Center, MML, National Institute of Standards and Technology, Gaithersburg, MD 20899.
authors.forename: Shozo
authors.initials: S
authors.lastname: Takagi
authors.affiliation: American Dental Association Foundation, Paffenbarger Research Center, MML, National Institute of Standards and Technology, Gaithersburg, MD 20899.
authors.forename: Laurence C
authors.initials: LC
authors.lastname: Chow
keywords: acid neutralization; basicity; calcium phosphate cement; endo-materials; mineral trioxide aggregate; setting time; tricalcium silicate