title: Potential exposure routes and accumulation kinetics for poly- and perfluorinated alkyl compounds for a freshwater amphipod: Gammarus spp. (Crustacea).
abstract: Gammarids were exposed to sediments from a deposition site located on the Rhône River (France) downstream of a fluoropolymer manufacturing plant. Gammarids accumulated to various extents four long-chain perfluoroalkyl carboxylic acids (PFCAs) from C9 to C13, one sulfonate, perfluorooctane sulfonate (PFOS) and three of its precursors (the perflurooctane sulfonamide (FOSA), the N-methyl perfluorooctane sulfonamidoacetic acid (MeFOSAA), the N-ethyl perfluorooctane sulfonamidoacetic acid (EtFOSAA) and the 6:2 fluorotelomer sulfonic acid (6:2 FTSA). Whatever the compound, the steady state was not achieved after a 3-week exposure; elimination was almost complete after a 3-week depuration period for perfluorononanoic acid (PFNA), PFOS, the three precursors and the 6:2FTSA. However, this was not the case for long-chain PFCAs, whose elimination rates decreased with increasing chain length. PFAS accumulation in gammarids occurred via the trophic and respiratory pathways, in proportions varying with the carbon chain length and the terminal moiety.
authors.affiliation: Irstea, UR MALY, Centre de Lyon-Villeurbanne, 5 rue de la Doua, BP 32108, 69626 Villeurbanne Cedex, France. Electronic address: d.bertin@hotmail.fr.
authors.forename: Delphine
authors.initials: D
authors.lastname: Bertin
authors.affiliation: Université de Bordeaux, Environnements et Paléoenvironnements Océaniques et Continentaux (EPOC), UMR 5805 CNRS, Laboratoire de Physico- et Toxico-Chimie de l'environnement (LPTC), 351 cours de la Libération, 33405 Talence, France; CNRS, Environnements et Paléoenvironnements Océaniques et Continentaux (EPOC), UMR 5805 CNRS, Laboratoire de Physico- et Toxico-Chimie de l'environnement (LPTC), 351 cours de la Libération, 33405 Talence, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Labadie
authors.affiliation: Irstea, UR MALY, Centre de Lyon-Villeurbanne, 5 rue de la Doua, BP 32108, 69626 Villeurbanne Cedex, France; Swiss Centre for Applied Ecotoxicology, Eawag/EPFL, EPFL ENAC IIE-GE, Station 2, CH-1015 Lausanne, Switzerland.
authors.forename: Benoît J D
authors.initials: BJD
authors.lastname: Ferrari
authors.affiliation: Irstea, UR MALY, Centre de Lyon-Villeurbanne, 5 rue de la Doua, BP 32108, 69626 Villeurbanne Cedex, France. Electronic address: asapin@rovaltainresearch.com.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Sapin
authors.affiliation: Irstea, UR MALY, Centre de Lyon-Villeurbanne, 5 rue de la Doua, BP 32108, 69626 Villeurbanne Cedex, France.
authors.forename: Jeanne
authors.initials: J
authors.lastname: Garric
authors.affiliation: Irstea, UR MALY, Centre de Lyon-Villeurbanne, 5 rue de la Doua, BP 32108, 69626 Villeurbanne Cedex, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Geffard
authors.affiliation: Université de Bordeaux, Environnements et Paléoenvironnements Océaniques et Continentaux (EPOC), UMR 5805 CNRS, Laboratoire de Physico- et Toxico-Chimie de l'environnement (LPTC), 351 cours de la Libération, 33405 Talence, France; CNRS, Environnements et Paléoenvironnements Océaniques et Continentaux (EPOC), UMR 5805 CNRS, Laboratoire de Physico- et Toxico-Chimie de l'environnement (LPTC), 351 cours de la Libération, 33405 Talence, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Budzinski
authors.affiliation: Irstea, UR MALY, Centre de Lyon-Villeurbanne, 5 rue de la Doua, BP 32108, 69626 Villeurbanne Cedex, France. Electronic address: marc.babut@irstea.fr.
authors.forename: Marc
authors.initials: M
authors.lastname: Babut
mesh_terms: D017738:Alkanesulfonic Acids / Q000032:analysis / Q000378:metabolism; D033304:Amphipoda / Q000378:metabolism*; D000818:Animals; D002264:Carboxylic Acids / Q000032:analysis / Q000378:metabolism; D004781:Environmental Exposure; D004784:Environmental Monitoring; D005466:Fluorocarbons / Q000032:analysis / Q000378:metabolism*; D005602:France; D005618:Fresh Water; D019015:Geologic Sediments / Q000032:analysis*; D007700:Kinetics; D013451:Sulfonic Acids / Q000032:analysis / Q000378:metabolism
chemical_list: D017738:Alkanesulfonic Acids; D002264:Carboxylic Acids; D005466:Fluorocarbons; D013451:Sulfonic Acids; C073608:perfluorooctane; C076994:perfluorooctane sulfonic acid
keywords: BSAF; Clearance; Exposure route; Gammarus spp.; Perfluorinated compounds; Sediment; Uptake rate