title: Effects of PREPARE, a Multi-component, School-Based HIV and Intimate Partner Violence (IPV) Prevention Programme on Adolescent Sexual Risk Behaviour and IPV: Cluster Randomised Controlled Trial.
abstract: Young South Africans, especially women, are at high risk of HIV. We evaluated the effects of PREPARE, a multi-component, school-based HIV prevention intervention to delay sexual debut, increase condom use and decrease intimate partner violence (IPV) among young adolescents. We conducted a cluster RCT among Grade eights in 42 high schools. The intervention comprised education sessions, a school health service and a school sexual violence prevention programme. Participants completed questionnaires at baseline, 6 and 12 months. Regression was undertaken to provide ORs or coefficients adjusted for clustering. Of 6244 sampled adolescents, 55.3 % participated. At 12 months there were no differences between intervention and control arms in sexual risk behaviours. Participants in the intervention arm were less likely to report IPV victimisation (35.1 vs. 40.9 %; OR 0.77, 95 % CI 0.61-0.99; t(40) = 2.14) suggesting the intervention shaped intimate partnerships into safer ones, potentially lowering the risk for HIV.
authors.affiliation: Health Systems Research Unit, South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town, 7505, South Africa. cathy.mathews@mrc.ac.za.|Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa. cathy.mathews@mrc.ac.za.
authors.forename: Catherine
authors.initials: C
authors.lastname: Mathews
authors.affiliation: Department of Health Promotion, Caphri Research Institute, Maastricht University, Maastricht, The Netherlands.
authors.forename: Sander M
authors.initials: SM
authors.lastname: Eggers
authors.affiliation: Health Systems Research Unit, South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town, 7505, South Africa.|Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
authors.forename: Loraine
authors.initials: L
authors.lastname: Townsend
authors.affiliation: Department of Health Promotion and Development, University of Bergen, Bergen, Norway.|Division of Mental Health, Norwegian Institute of Public Health, Oslo, Norway.
authors.forename: Leif E
authors.initials: LE
authors.lastname: Aarø
authors.affiliation: Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.|Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
authors.forename: Petrus J
authors.initials: PJ
authors.lastname: de Vries
authors.affiliation: Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.|Department of Health Sciences, University of York, York, England, UK.
authors.forename: Amanda J
authors.initials: AJ
authors.lastname: Mason-Jones
authors.affiliation: Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
authors.forename: Petra
authors.initials: P
authors.lastname: De Koker
authors.affiliation: Health Systems Research Unit, South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town, 7505, South Africa.|Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
authors.forename: Tracy
authors.initials: T
authors.lastname: McClinton Appollis
authors.affiliation: Health Systems Research Unit, South African Medical Research Council, P.O. Box 19070, Tygerberg, Cape Town, 7505, South Africa.|Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
authors.forename: Yolisa
authors.initials: Y
authors.lastname: Mtshizana
authors.affiliation: Adolescent Health Research Unit, Division of Child & Adolescent Psychiatry, University of Cape Town, Cape Town, South Africa.
authors.forename: Joy
authors.initials: J
authors.lastname: Koech
authors.affiliation: Department of Health Promotion and Development, University of Bergen, Bergen, Norway.
authors.forename: Annegreet
authors.initials: A
authors.lastname: Wubs
authors.affiliation: Department of Health Promotion, Caphri Research Institute, Maastricht University, Maastricht, The Netherlands.
authors.forename: Hein
authors.initials: H
authors.lastname: De Vries
mesh_terms: D000293:Adolescent; D000294:Adolescent Behavior; D000328:Adult; D017280:Condoms / Q000706:statistics & numerical data; D019548:Crime Victims; D005260:Female; D015658:HIV Infections / Q000517:prevention & control*; D006801:Humans; D007398:Interpersonal Relations; D000066511:Intimate Partner Violence / Q000517:prevention & control* / Q000523:psychology; D012309:Risk-Taking; D021841:Safe Sex; D012572:School Health Services; D012574:Schools; D012736:Sex Education / Q000379:methods*; D012742:Sex Offenses; D012725:Sexual Behavior / Q000523:psychology*; D012747:Sexual Partners; D011795:Surveys and Questionnaires
keywords: Adolescents; HIV prevention; Intimate partner violence; Randomised controlled trial; Sexual risk behaviour