title: Simulation and experiment of soft-tissue deformation in prostate brachytherapy.
abstract: Soft-tissue deformation is one of the major reasons for the inaccurate positioning of percutaneous needle insertion process. In this article, simulations and experiments of the needle insertion soft-tissue process are both applied to study soft-tissue deformation. A needle deflection model based on the mechanics is used to calculate the needle deflection during the interaction process. The obtained needle deflection data are applied into finite element analysis process as the system input. The uniaxial tensile strength tests, compression tests, and static indentation experiments are used to obtain the soft-tissue parameters and choose the best strain-energy function to model in the simulation. Magnetic resonance imaging is used to reconstruct the prostate, establishing both prostate three-dimensional finite element model and artificial prostate model. The needle-soft tissue interaction simulation results are compared with those of the needle insertion experiment. The displacement data of the mark point in the experiment are comparable to the simulation results. It is concluded that, using this simulation method, the surgeon can predict the deformation of the tissue and the displacement of the target in advance.
authors.affiliation: Center for Advanced Mechanisms and Robotics, School of Mechanical Engineering, Tianjin University, Tianjin, China.
authors.forename: Dong
authors.initials: D
authors.lastname: Liang
authors.affiliation: Center for Advanced Mechanisms and Robotics, School of Mechanical Engineering, Tianjin University, Tianjin, China shanjmri@tju.edu.cn.
authors.forename: Shan
authors.initials: S
authors.lastname: Jiang
authors.affiliation: Center for Advanced Mechanisms and Robotics, School of Mechanical Engineering, Tianjin University, Tianjin, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Center for Advanced Mechanisms and Robotics, School of Mechanical Engineering, Tianjin University, Tianjin, China.
authors.forename: Xingji
authors.initials: X
authors.lastname: Wang
mesh_terms: D001696:Biomechanical Phenomena; D001918:Brachytherapy / Q000295:instrumentation / Q000379:methods* / Q000706:statistics & numerical data; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008953:Models, Anatomic; D008954:Models, Biological; D009339:Needles; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000532:radiotherapy*; D011880:Radiotherapy Planning, Computer-Assisted
keywords: Prostate brachytherapy; finite element modeling; needle insertion experiment; soft-tissue deformation; tissue parameters acquisition