title: Differential profiles in auditory social cognition deficits between adults with autism and schizophrenia spectrum disorders: A preliminary analysis.
abstract: Impairment in social cognition, including emotion recognition, has been extensively studied in both Autism Spectrum Disorders (ASD) and Schizophrenia (SZ). However, the relative patterns of deficit between disorders have been studied to a lesser degree. Here, we applied a social cognition battery incorporating both auditory (AER) and visual (VER) emotion recognition measures to a group of 19 high-functioning individuals with ASD relative to 92 individuals with SZ, and 73 healthy control adult participants. We examined group differences and correlates of basic auditory processing and processing speed. Individuals with SZ were impaired in both AER and VER while ASD individuals were impaired in VER only. In contrast to SZ participants, those with ASD showed intact basic auditory function. Our finding of a dissociation between AER and VER deficits in ASD relative to Sz support modality-specific theories of emotion recognition dysfunction. Future studies should focus on visual system-specific contributions to social cognitive impairment in ASD.
authors.affiliation: Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Columbia University, Department of Psychiatry, New York, NY, USA.
authors.forename: Russell H
authors.initials: RH
authors.lastname: Tobe
authors.affiliation: Columbia University, Department of Psychiatry, New York, NY, USA; New York State Psychiatric Institute, New York, NY, USA.
authors.forename: Cheryl M
authors.initials: CM
authors.lastname: Corcoran
authors.affiliation: Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
authors.forename: Melissa
authors.initials: M
authors.lastname: Breland
authors.affiliation: Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Columbia University, Department of Neurology, Cognitive Neuroscience Division, New York, NY, USA.
authors.forename: Anna
authors.initials: A
authors.lastname: MacKay-Brandt
authors.affiliation: Columbia University, Department of Psychiatry, New York, NY, USA.
authors.forename: Casimir
authors.initials: C
authors.lastname: Klim
authors.affiliation: Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA.
authors.forename: Stanley J
authors.initials: SJ
authors.lastname: Colcombe
authors.affiliation: Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; University of California San Francisco, Department of Psychiatry, San Francisco, CA, USA.
authors.forename: Bennett L
authors.initials: BL
authors.lastname: Leventhal
authors.affiliation: Nathan Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Columbia University, Department of Psychiatry, New York, NY, USA; New York State Psychiatric Institute, New York, NY, USA. Electronic address: javitt@nki.rfmh.org.
authors.forename: Daniel C
authors.initials: DC
authors.lastname: Javitt
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D001307:Auditory Perception; D000067877:Autism Spectrum Disorder / Q000523:psychology*; D003071:Cognition; D000066499:Facial Recognition; D005260:Female; D006801:Humans; D008297:Male; D011581:Psychological Tests; D011618:Psychotic Disorders / Q000523:psychology*; D021641:Recognition, Psychology; D012565:Schizophrenic Psychology; D012938:Social Perception
keywords: Auditory emotion recognition; Autism; Facial affect recogntion; Schizophrenia; Social cognition; Visual emotion recognition