title: Perivesical unicentric Castleman disease initially suspected to be metastatic prostate cancer.
abstract: Unicentric Castleman disease (UCD) is a relatively rare lymphoproliferative disease, which commonly presents as a mediastinal mass and less frequently involves abdomen, pelvis, and retroperitoneum. We report a case of a 64-year-old man with newly diagnosed low-volume, Gleason 3 + 3 = 6 prostate adenocarcinoma, who in considering active surveillance versus treatment was found to have a left perivesical and iliac chain lymphadenopathy concerning for potential metastatic involvement. He underwent magnetic resonance imaging with ferumoxytol to assist in the diagnostic evaluation to better characterize his lymphadenopathy. Subsequently, he underwent robotic-assisted laparoscopic bilateral pelvic lymph node dissection and resection of left perivesical mass exhibiting hyaline vascular variant of UCD.
authors.affiliation: Department of Urology, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Guthrie
authors.affiliation: Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: John V
authors.initials: JV
authors.lastname: Thomas
authors.affiliation: Department of Pathology, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Deniz
authors.initials: D
authors.lastname: Peker
authors.affiliation: Department of Molecular Imaging Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
authors.forename: Baris
authors.initials: B
authors.lastname: Turkbey
authors.affiliation: Department of Urology, University of Alabama at Birmingham, Birmingham, AL, USA; Department of Radiology, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Soroush
authors.initials: S
authors.lastname: Rais-Bahrami
keywords: Castleman disease; ferumoxytol; fusion biopsy; multiparametric magnetic resonance imaging; prostate adenocarcinoma