title: Ventricular Microaneurysms in Moyamoya Angiopathy Visualized with 7T MR Angiography.
abstract: The pathophysiologic role of hemodynamic alteration to peripheral vessels in Moyamoya angiopathy and the formation of microaneurysms remains unclear. The purpose of this study was to investigate microaneurysms in collateral Moyamoya vessels by using 7T ultra-high-field MR imaging. Ten patients with Moyamoya disease were evaluated with TOF-MRA at 7T acquired with 0.22 × 0.22 × 0.41 mm(3) resolution. In 10 patients, 4 microaneuryms located in the ventricles were delineated. The mean diameters of collateral vessels and microaneurysms arising from those vessels were 0.87 mm (range, 0.79-1.07 mm) and 0.80 mm (range, 0.56-0.96 mm), respectively. In 1 case with follow-up scans 6 months after a direct extracranial-intracranial bypass operation, the microaneurysm disappeared. Ventricular microaneurysms in Moyamoya angiopathy collateral vessels, inaccessible by conventional imaging techniques, can be detected by 7T TOF-MRA.
authors.affiliation: From the Departments of Neurosurgery (T.M., U.S., K.H.W.) Department of Neurosurgery (T.M.), Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan Erwin L. Hahn Institute for Magnetic Resonance Imaging (T.M., M.E.L., K.H.W.), University Duisburg-Essen, Essen, Germany Toshinori.Matsushige@uk-essen.de karsten.wrede@uk-essen.de.
authors.forename: T
authors.identifier: 0000-0002-4446-7636
authors.initials: T
authors.lastname: Matsushige
authors.affiliation: Department of Neurology (M.K., P.B.), Alfried Krupp Hospital, Essen, Germany.
authors.forename: M
authors.identifier: 0000-0002-5667-3621
authors.initials: M
authors.lastname: Kraemer
authors.affiliation: Diagnostic and Interventional Radiology and Neuroradiology (M.S., M.F.), University Hospital Essen, University Duisburg-Essen, Essen, Germany Department of Neuroradiology (M.S.), University Hospital Giessen, Giessen, Germany.
authors.forename: M
authors.identifier: 0000-0002-9940-1503
authors.initials: M
authors.lastname: Schlamann
authors.affiliation: Department of Neurology (M.K., P.B.), Alfried Krupp Hospital, Essen, Germany.
authors.forename: P
authors.identifier: 0000-0002-9544-7256
authors.initials: P
authors.lastname: Berlit
authors.affiliation: Diagnostic and Interventional Radiology and Neuroradiology (M.S., M.F.), University Hospital Essen, University Duisburg-Essen, Essen, Germany.
authors.forename: M
authors.identifier: 0000-0002-5584-9824
authors.initials: M
authors.lastname: Forsting
authors.affiliation: Erwin L. Hahn Institute for Magnetic Resonance Imaging (T.M., M.E.L., K.H.W.), University Duisburg-Essen, Essen, Germany Division of Medical Physics in Radiology (M.E.L.), German Cancer Research Center, Heidelberg, Germany.
authors.forename: M E
authors.identifier: 0000-0002-4128-9440
authors.initials: ME
authors.lastname: Ladd
authors.affiliation: From the Departments of Neurosurgery (T.M., U.S., K.H.W.).
authors.forename: U
authors.identifier: 0000-0002-9073-1821
authors.initials: U
authors.lastname: Sure
authors.affiliation: From the Departments of Neurosurgery (T.M., U.S., K.H.W.) Erwin L. Hahn Institute for Magnetic Resonance Imaging (T.M., M.E.L., K.H.W.), University Duisburg-Essen, Essen, Germany.
authors.forename: K H
authors.identifier: 0000-0001-7076-3503
authors.initials: KH
authors.lastname: Wrede
mesh_terms: D003097:Collateral Circulation; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D000071071:Microaneurysm / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D008875:Middle Aged; D009072:Moyamoya Disease / Q000150:complications / Q000000981:diagnostic imaging* / Q000473:pathology