title: XIBD: software for inferring pairwise identity by descent on the X chromosome.
abstract: XIBD performs pairwise relatedness mapping on the X chromosome using dense single nucleotide polymorphism (SNP) data from either SNP chips or next generation sequencing data. It correctly accounts for the difference in chromosomal numbers between males and females and estimates global relatedness as well as regions of the genome that are identical by descent (IBD). XIBD also generates novel graphical summaries of all pairwise IBD tracts for a cohort making it very useful for disease locus mapping.
  
  
  
  XIBD is written in R/Rcpp and executed from shell scripts that are freely available from http://bioinf.wehi.edu.au/software/XIBD along with accompanying reference datasets.
  
  
  
  henden.l@wehi.edu.au
  
  
  
  Supplementary data are available at Bioinformatics online.
authors.affiliation: Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia Department of Medical Biology.
authors.forename: Lyndal
authors.initials: L
authors.lastname: Henden
authors.affiliation: School of Physics.
authors.forename: David
authors.initials: D
authors.lastname: Wakeham
authors.affiliation: Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia Department of Medical Biology School of Mathematics and Statistics, University of Melbourne, Melbourne, VIC, Australia.
authors.forename: Melanie
authors.initials: M
authors.lastname: Bahlo
mesh_terms: D041321:Chromosomes, Human, X; D005260:Female; D055106:Genome-Wide Association Study; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D008297:Male; D020641:Polymorphism, Single Nucleotide; D012984:Software