title: [The effect of subchronic inhalations of nitric oxide on metabolic processes in blood of experimental animals].
abstract: Metabolic processes were investigated in plasma and erythrocytes of Wistar rats exposed to daily 10-min sessions of NO inhalation for 30 days. These included determination of glucose and lactate, catalase activity, and activities of aldehyde dehydrogenase (ALDH), lactate dehydrogenase (LDH), and catalase. NO inhalation in a concentration of 20 ppm, 50 ppm and 100 ppm caused an increase in glucose and lactate. Inhalation of 100 ppm NO also increased catalase activity. Inhalation of all NO concentrations resulted in a decrease of ALDH activity, while the decrease in LDH activity was observed at NO concentrations of 50-100 ppm.
authors.affiliation: Privolzhsky Federal Research Medical Centre, Nizhny Novgorod, Russia.
authors.forename: A G
authors.initials: AG
authors.lastname: Soloveva
authors.affiliation: Privolzhsky Federal Research Medical Centre, Nizhny Novgorod, Russia.
authors.forename: S P
authors.initials: SP
authors.lastname: Peretyagin
mesh_terms: D000280:Administration, Inhalation; D000444:Aldehyde Dehydrogenase / Q000097:blood; D000818:Animals; D001769:Blood / Q000187:drug effects / Q000378:metabolism*; D001786:Blood Glucose / Q000032:analysis; D002374:Catalase / Q000097:blood; D004305:Dose-Response Relationship, Drug; D007770:L-Lactate Dehydrogenase / Q000097:blood; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009569:Nitric Oxide / Q000008:administration & dosage* / Q000494:pharmacology; D017208:Rats, Wistar
chemical_list: D001786:Blood Glucose; D009569:Nitric Oxide; D019344:Lactic Acid; D007770:L-Lactate Dehydrogenase; D002374:Catalase; D000444:Aldehyde Dehydrogenase
keywords: blood; glucose; lactate; nitric oxide; oxidoreductase