title: Paraneoplastic retinopathy associated with occult bladder cancer.
abstract: The aim was to report the first case of cancer-associated retinopathy (CAR) presenting before bladder cancer diagnosis. A 71-year-old woman with a history of bilateral vision loss underwent subsequent complete ophthalmic examination include a fluorescein angiography, full-field electroretinogram (ERG), serology including serum antibodies for CAR, and positron emission tomography-computed tomography (PET-CT) scan. The patient was diagnosed with bladder carcinoma revealed by PET-CT. Timely recognition of this entity may be crucial for an increased patient survival thus adult onset progressive photoreceptor dysfunction, confirmed by ERG, should alert to a possible remote effect of known or occult malignancy. In the latter, PET-CT may be exploited as a powerful diagnostic tool.
authors.affiliation: Department of Ophthalmology, M N Eye Hospital, Chennai, Tamil Nadu, India.
authors.forename: M
authors.initials: M
authors.lastname: Nivean
authors.forename: Danson V
authors.initials: DV
authors.lastname: Muttuvelu
authors.forename: Pia
authors.initials: P
authors.lastname: Afzelius
authors.forename: Dalia C
authors.initials: DC
authors.lastname: Berman
mesh_terms: D000368:Aged; D001706:Biopsy; D004596:Electroretinography; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D059545:Paraneoplastic Syndromes, Ocular / Q000175:diagnosis*; D049268:Positron-Emission Tomography; D012164:Retinal Diseases / Q000175:diagnosis* / Q000209:etiology; D041623:Tomography, Optical Coherence; D001749:Urinary Bladder Neoplasms / Q000150:complications* / Q000175:diagnosis; D014792:Visual Acuity