title: Evaluation of various hematological parameters in patients with periodontitis after nonsurgical therapy at different intervals.
abstract: OBJECTIVE
  Chronic low-level bacteremia and a systemic inflammatory response have been suggested as a pathogenetic link between periodontal disease and atherosclerosis. The objective of this study is to evaluate the effect of nonsurgical periodontal therapy on various hematological parameters in patients with periodontitis.
  
  
  METHODS
  A total of 30 periodontitis patients were selected for the study. Clinical parameters such as plaque index, gingival index, and probing pocket depth were assessed. For each patient, venous blood sample were collected, and the estimation of total leukocyte count (TLC), differential leukocyte count, platelet count, and erythrocyte sedimentation rate (ESR) was carried out. All the clinical and hematological parameters were measured at baseline, 1 week and 2 weeks after nonsurgical periodontal therapy.
  
  
  RESULTS
  The study results showed that there was a statistically significant decrease in TLC, ESR, and platelet count at 1 week and 2 weeks following nonsurgical periodontal therapy.
  
  
  CONCLUSIONS
  In this study, it has been concluded that there is a decrease in the hematological parameters after nonsurgical periodontal therapy, which may also reduce the risk of atherosclerosis formation in the blood vessel and possibly prevent cardiovascular diseases.
authors.affiliation: Department of Periodontology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Srinivasa Tenkasale
authors.initials: ST
authors.lastname: Siddeshappa
authors.affiliation: Department of Periodontology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Sonika
authors.initials: S
authors.lastname: Nagdeve
authors.affiliation: Department of Periodontology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Ramreddy Krishnarao
authors.initials: RK
authors.lastname: Yeltiwar
authors.affiliation: Department of Periodontology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Humera
authors.initials: H
authors.lastname: Parvez
authors.affiliation: Department of Periodontology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Sushmita
authors.initials: S
authors.lastname: Deonani
authors.affiliation: Department of Periodontology, Rungta College of Dental Sciences and Research, Bhilai, Chhattisgarh, India.
authors.forename: Vikas
authors.initials: V
authors.lastname: Diwan
keywords: Atherosclerosis; nonsurgical periodontal therapy; periodontitis; platelet count; total leukocytes count