title: Glioblastoma in hemihydranencephaly: preoperative and postoperative language ability of the right hemisphere.
abstract: We present the first case report describing a craniotomy for a glioblastoma in a patient with hemihydranencephaly (HHE). Ten years ago our patient had average cognitive and language functions, indicating very good adaption of his single right hemisphere. Due to the tumour he developed a deceleration, deficits in language functions and mild impairments of basic cognitive functions. Further neuroplastic reorganisations of his right hemisphere in response to the tumour growth are discussed. The favourable postoperative outcome supported the decision for careful tumour resection in this patient with HHE.
authors.affiliation: Department of Neurosurgery, University Hospital Schleswig-Holstein, Arnold-Heller-Straße 3, 24105, Kiel, Germany. juliane.becker@uksh.de.
authors.forename: Juliane
authors.initials: J
authors.lastname: Becker
authors.affiliation: Division of Neuroradiology, vascular and interventional Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
authors.forename: Margit
authors.initials: M
authors.lastname: Jehna
authors.affiliation: Department of Radiology and Neuroradiology, University Hospital Schleswig-Holstein, Kiel, Germany.
authors.forename: Naomi
authors.initials: N
authors.lastname: Larsen
authors.affiliation: Department of Neurosurgery, University Hospital Schleswig-Holstein, Arnold-Heller-Straße 3, 24105, Kiel, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Synowitz
authors.affiliation: Department of Neuropsychology, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany.
authors.forename: Gesa
authors.initials: G
authors.lastname: Hartwigsen
mesh_terms: D003399:Craniotomy / Q000009:adverse effects*; D005909:Glioblastoma / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D006801:Humans; D006832:Hydranencephaly / Q000150:complications* / Q000601:surgery; D007806:Language Disorders / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*
keywords: Brain tumour; Hemihydranencephaly; Hemisphere agenesis; Neuropsychological diagnostic; Neurosurgery