title: Increased Intraocular Pressure in a Patient With Septooptic Dysplasia: A Case Report.
abstract: Previous studies have described septooptic dysplasia (SOD) to describe patients who have optic nerve hypoplasia, the absence of septum pellucidum, and pituitary hypoplasia. Other rare ophthalmic associations have been described, such as low-tension glaucoma. We report the ocular findings of a patient with SOD who had high intraocular pressure (IOP) and glaucoma as a part of the syndrome.
  
  
  
  To report the ocular findings in a Puerto Rican patient with SOD and increased IOP.
  
  
  
  A patient with De Morsier syndrome underwent a comprehensive eye examination, Humphrey visual fields, and Stratus optical coherence tomography, and was referred for neuroradiologic examination. The patient had increased IOP, visual field loss, and asymmetric optic nerve hypoplasia. The IOP was lowered with topical hypotensive medications.
  
  
  
  The patient with the De Morsier syndrome had poor visual acuity, high IOP, visual field, and optical coherence tomography results that were all compatible with glaucoma. Further studies comparing ocular findings in patients with several mutations leading to De Morsier syndrome are warranted. To our knowledge, this is the first report on a patient with glaucoma as a part of the syndrome.
authors.affiliation: *Medical Sciences Campus, School of Medicine, University of Puerto Rico Departments of †Surgery ‡Ophthalmology, Medical Sciences Campus, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico.
authors.forename: Jan P
authors.initials: JP
authors.lastname: Ulloa-Padilla
authors.forename: Natalio J
authors.initials: NJ
authors.lastname: Izquierdo
authors.forename: Armando
authors.initials: A
authors.lastname: Oliver
mesh_terms: D000368:Aged; D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D057066:Low Tension Glaucoma / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D025962:Septo-Optic Dysplasia / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology*; D041623:Tomography, Optical Coherence; D014786:Vision Disorders / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D014792:Visual Acuity / Q000502:physiology; D058609:Visual Field Tests; D014794:Visual Fields / Q000187:drug effects / Q000502:physiology
chemical_list: D000959:Antihypertensive Agents