title: Senescence-Associated Vacuoles, a Specific Lytic Compartment for Degradation of Chloroplast Proteins?
abstract: Degradation of chloroplasts and chloroplast components is a distinctive feature of leaf senescence. In spite of its importance in the nutrient economy of plants, knowledge about the mechanism(s) involved in the breakdown of chloroplast proteins is incomplete. A novel class of vacuoles, "senescence-associated vacuoles" (SAVs), characterized by intense proteolytic activity appear during senescence in chloroplast-containing cells of leaves. Since SAVs contain some chloroplast proteins, they are candidate organelles to participate in chloroplast breakdown. In this review we discuss the characteristics of SAVs, and their possible involvement in the degradation of Rubisco, the most abundant chloroplast protein. Finally, SAVs are compared with other extra-plastidial protein degradation pathways operating in senescing leaves.
authors.affiliation: Instituto de Fisiología Vegetal (INFIVE, CONICET-UNLP), cc327, La Plata 1900, Argentina. ccarrion@agro.unlp.edu.ar.
authors.forename: Cristian A
authors.initials: CA
authors.lastname: Carrión
authors.affiliation: Instituto de Fisiología Vegetal (INFIVE, CONICET-UNLP), cc327, La Plata 1900, Argentina. danamartinez@conicet.gov.ar.
authors.forename: Dana E
authors.initials: DE
authors.lastname: Martínez
authors.affiliation: Instituto de Fisiología Vegetal (INFIVE, CONICET-UNLP), cc327, La Plata 1900, Argentina. lorenzacosta@agro.unlp.edu.ar.
authors.forename: M Lorenza
authors.initials: ML
authors.lastname: Costa
authors.affiliation: Instituto de Fisiología Vegetal (INFIVE, CONICET-UNLP), cc327, La Plata 1900, Argentina. jguiamet@fcnym.unlp.edu.ar.
authors.forename: Juan José
authors.initials: JJ
authors.lastname: Guiamet
keywords: Rubisco; SAG12; chloroplast degradation; leaf senescence; proteases; senescence-associated vacuoles