title: Laparoscopic resection of right colon cancer-a matched pairs analysis.
abstract: OBJECTIVE
  Laparoscopy for colorectal cancer resection bares early post-operative advantages and results in equal oncologic long-term outcome. However, data on laparoscopic right hemi-colectomy is scarce. Aim of the present study was to analyze a well selected collective of patients with right-sided colon cancer treated open and laparoscopically with regard to peri-operative and long-term outcome.
  
  
  METHODS
  We analyzed all patients who underwent right-sided hemi-colectomy for colon cancer between January 1996 and March 2013. Data was extracted from our prospective database. Inclusion criteria were tumor localization in the ascending colon, oncologic resection, histology of an adenocarcinoma, tumors UICC I-III, and R0 resection. Exclusion criteria were multiple malignancies including colon, emergency operation, adenoma or pT0 status, and UICC IV. For the matched pairs approach between patients undergoing laparoscopic (LAP) or open (OPEN) surgery, the parameters age, UICC stage, tumor grading, and sex were applied.
  
  
  RESULTS
  A total of 188 patients was included in the analysis with n = 94 in both the LAP and the OPEN group. Some peri-operative results demonstrated advantages for laparoscopy including median return to liquid (p < 0.0001) and solid diet (p = 0.008), median length of ICU stay (p < 0.0001), and median length of hospital stay (p = 0.022). No significant differences were revealed for complication rates, rates of anastomotic leakage, or 30-day mortality. Lymph node yield was identical. Also, no differences in oncologic long-term outcome were detected. Rates for local recurrence were 4.3 and 2.0 %.
  
  
  CONCLUSIONS
  This matched pairs analysis verifies peri-operative advantages of laparoscopy explicitly for the sub-group of CRC patients undergoing right-sided hemi-colectomy in comparison to open surgery while demonstrating equivalent oncologic long-term results.
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Zimmermann
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Benecke
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: C
authors.initials: C
authors.lastname: Jung
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Hoffmann
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Nolde
authors.affiliation: Westküstenklinikum Heide, Department of Surgery, Heide, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Schlöricke
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: H P
authors.initials: HP
authors.lastname: Bruch
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Keck
authors.affiliation: Department of Surgery, University Medical Center Schleswig-Holstein Campus Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany. tilman.laubert@uksh.de.
authors.forename: T
authors.initials: T
authors.lastname: Laubert
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003106:Colon / Q000473:pathology* / Q000601:surgery*; D003110:Colonic Neoplasms / Q000601:surgery*; D003710:Demography; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D016555:Matched-Pair Analysis; D008875:Middle Aged; D009367:Neoplasm Staging; D016019:Survival Analysis
keywords: CRC patients; Hemi-colectomy; Laparoscopic surgery; Open surgery