title: New Hopes in Cancer Battle - A Review of New Molecules and Treatment Strategies.
abstract: BACKGROUND
  Cancer is one of the most serious illnesses of our civilization. Therefore, scientists of different disciplines try to find new treatment strategies and new chemical molecules which might be useful in a cancer treatment.
  
  
  OBJECTIVE
  The goal of this work is to perform the most significant achievements in the area of chemotherapeutic treatment, published during the last two years.
  
  
  METHODS
  We reviewed almost 80 contributions, searching for new molecules with anticancer activity and treatment strategies.
  
  
  RESULTS
  We have presented tens of new anticancer molecules interacting with DNA or affecting cell cycle and new findings in this area. These compounds are chemically synthesized as well as are isolated from natural sources. The discovered molecules may induce cancer cells apoptosis, improve other cancer treatments, such as radiotherapy or reduce side effects of chemotherapy.
  
  
  CONCLUSIONS
  The review shows that the cancer battle is still in progress and the combined studies in different disciplines, devoted to this subject, are a rapidly expanding area.
authors.affiliation: Institute of Chemistry, Environmental Protection and Biotechnology, The Faculty of Mathematics and Natural Sciences, Jan Dlugosz University in Czestochowa, 42-201, Czestochowa, Poland. nmarika93@wp.pl.
authors.forename: Marika
authors.initials: M
authors.lastname: Turek
authors.forename: Magdalena
authors.initials: M
authors.lastname: Krzyczmonik
authors.affiliation: Department of Heteroorganic Chemistry, Centre of Molecular and Macromolecular Studies, Polish Academy of Sciences, Box: 90-363, Lódz, Poland. pbalczew@cbmm.lodz.pl.
authors.forename: Piotr
authors.initials: P
authors.lastname: Balczewski
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D017209:Apoptosis / Q000187:drug effects; D002453:Cell Cycle / Q000187:drug effects; D004247:DNA / Q000378:metabolism; D016503:Drug Delivery Systems; D019008:Drug Resistance, Neoplasm / Q000187:drug effects; D006801:Humans; D009369:Neoplasms / Q000188:drug therapy*
chemical_list: D000970:Antineoplastic Agents; D004247:DNA