title: Spinal cord ependymoma: a review of the literature and case series of ten patients.
abstract: Spinal cord ependymoma (SCE) is a rare tumor that is most commonly low-grade. Complete surgical resection has been established as first-line treatment and can be curative. However, SCEs tend to recur when complete tumor resection is not possible. Evidence supporting the use of adjuvant radiation and chemotherapy is not definitive. We review the most recent literature on SCE covering a comprehensive range of topics spanning the biology, presentation, clinical management, and outcomes. In addition, we present a case series of ten SCE patients with the goal of contributing to existing knowledge of this rare disease.
authors.affiliation: Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Emma
authors.initials: E
authors.lastname: Celano
authors.affiliation: Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: Arsalaan
authors.initials: A
authors.lastname: Salehani
authors.affiliation: Emory University School of Medicine, Atlanta, GA, USA.
authors.forename: James G
authors.initials: JG
authors.lastname: Malcolm
authors.affiliation: Emory University School of Medicine, Atlanta, GA, USA.|Department of Biomedical Engineering, Georgia Institute of Technology, Atlanta, GA, USA.
authors.forename: Erik
authors.initials: E
authors.lastname: Reinertsen
authors.affiliation: Department of Neurosurgery, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel Philips Ambulatory Care Center, 10 Union Square, 5th Floor, Suite 5E, New York, NY, 10003, USA. constantinos.hadjipanayis@mountsinai.org.
authors.forename: Constantinos G
authors.initials: CG
authors.lastname: Hadjipanayis
mesh_terms: D000328:Adult; D015331:Cohort Studies; D004806:Ependymoma / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D013116:Spinal Cord / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D013120:Spinal Cord Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000473:pathology / Q000628:therapy*; D055815:Young Adult
keywords: Case series; Ependymoma; Review; Spinal cord; Tumor