title: Venous glucose, serum lactate and base deficit as biochemical predictors of mortality in patients with polytrauma.
abstract: BACKGROUND
  The trauma and injury severity score (TRISS) and Acute Physiology and Chronic Health Evaluation IV (APACHE IV) are accurate but complex. This study aimed to compare venous glucose, levels of serum lactate, and base deficit in polytraumatized patients as simple parameters to predict the mortality in these patients versus (TRISS) and (APACHE IV).
  
  
  METHODS
  This was a comparative cross-sectional study of 282 patients with polytrauma presented to the Emergency Department (ED).
  
  
  RESULTS
  The best cut off value of TRISS probability of survival score for prediction of mortality among poly-traumatized patients was ≤90. APACHE IV demonstrated 67% sensitivity and 95% specificity at 95% CI at cut off point 99. The best cutoff value of Random Blood Sugar was >140 mg/dl, with 89% sensitivity, 49% specificity; base deficit was less than -5.6 with 64% sensitivity, 93% specificity; lactate was >2.6 mmol/L with 92%, sensitivity, 42% specificity.
  
  
  CONCLUSIONS
  Venous glucose, serum lactate and base deficit are easy and rapid biochemical predictors of mortality in patients with polytrauma. These predictors could be used as TRISS and APACHE IV in predicting mortality.
authors.affiliation: Department of Emergency Medicine, Suez Canal University Faculty of Medicine, Ismailia, Egypt. sameh_er2005@hotmail.com.
authors.forename: Sameh
authors.initials: S
authors.lastname: Saad
authors.affiliation: Department of Emergency Medicine, Suez Canal University Faculty of Medicine, Ismailia, Egypt.
authors.forename: Naglaa
authors.initials: N
authors.lastname: Mohamed
authors.affiliation: Department of General Surgery, Suez Canal University Faculty of Medicine, Ismailia, Egypt.
authors.forename: Amr
authors.initials: A
authors.lastname: Moghazy
authors.affiliation: Department of General Surgery, Suez Canal University Faculty of Medicine, Ismailia, Egypt.
authors.forename: Gouda
authors.initials: G
authors.lastname: Ellabban
authors.affiliation: Department of General Surgery, Suez Canal University Faculty of Medicine, Ismailia, Egypt.
authors.forename: Soliman
authors.initials: S
authors.lastname: El-Kamash
mesh_terms: D018806:APACHE; D000328:Adult; D015415:Biomarkers / Q000097:blood*; D001786:Blood Glucose; D003430:Cross-Sectional Studies; D004534:Egypt / Q000453:epidemiology; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D015601:Injury Severity Score; D019344:Lactic Acid / Q000097:blood; D008297:Male; D009104:Multiple Trauma / Q000097:blood / Q000401:mortality*; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers; D001786:Blood Glucose; D019344:Lactic Acid