title: UK guidelines for the management of bone sarcomas.
abstract: This document is an update of the British Sarcoma Group guidelines published in 2010. The aim is to provide a reference standard for the clinical care of patients in the UK with bone sarcomas. Recent recommendations by the European Society of Medical Oncology, The National Comprehensive Cancer Network and The National Institute for Health and Care Excellence have been incorporated, and the literature since 2010 reviewed. The standards represent a consensus amongst British Sarcoma Group members in 2015. It is acknowledged that these guidelines will need further updates as care evolves. The key recommendations are that bone pain or a palpable mass should always lead to further investigation and that patients with clinico-radiological findings suggestive of a primary bone tumour at any site in the skeleton should be referred to a specialist centre and managed by a fully accredited bone sarcoma multidisciplinary team. Treatment recommendations are provided for the major tumour types and for localised, metastatic and recurrent disease. Follow up schedules are suggested.
authors.affiliation: Newcastle upon Tyne Hospitals NHS Foundation Trust, Freeman Hospital, Newcastle upon Tyne, NE7 7DN UK.
authors.forename: Craig
authors.initials: C
authors.lastname: Gerrand
authors.affiliation: Nuffield Orthopaedic Centre, Oxford, OX3 7LD UK.
authors.forename: Nick
authors.initials: N
authors.lastname: Athanasou
authors.affiliation: Royal Manchester Children's Hospital, Manchester, M13 9WL UK.
authors.forename: Bernadette
authors.initials: B
authors.lastname: Brennan
authors.affiliation: Royal Orthopaedic Hospital, Birmingham, B31 2AP UK.
authors.forename: Robert
authors.initials: R
authors.lastname: Grimer
authors.affiliation: The Royal Marsden, Sutton, SM2 5PT UK.
authors.forename: Ian
authors.initials: I
authors.lastname: Judson
authors.affiliation: Birmingham Children's Hospital, Birmingham, B4 6NH UK.
authors.forename: Bruce
authors.initials: B
authors.lastname: Morland
authors.affiliation: Queen Elizabeth Hospital, Birmingham, B15 2TH UK.
authors.forename: David
authors.initials: D
authors.lastname: Peake
authors.affiliation: University College Hospital, London, NW1 2PG UK.
authors.forename: Beatrice
authors.initials: B
authors.lastname: Seddon
authors.affiliation: University College Hospital, London, NW1 2PG UK.
authors.forename: Jeremy
authors.initials: J
authors.lastname: Whelan