title: Callosal Disconnection Syndrome Associated with Relapsing Polychondritis.
abstract: Relapsing polychondritis (RP) is a rare inflammatory disorder of the cartilagenous structures, and it sometimes involves the central nervous system. Encephalitis associated with RP causes a wide variety of symptoms according to the affected sites. We herein report the first case of 72-year-old right-handed man who developed acute meningoencephalitis associated with RP involving the corpus callous. After immunosuppressive therapy, his symptoms dramatically improved, but difficulty in performing bimanual movements with occasional diagonistic dyspraxia in his right hand remained. Because callosal signs are easily missed, especially in acute settings, it would be useful to know that RP can sometimes cause callosal disconnection syndrome.
authors.affiliation: Department of Behavioral Neurology & Cognitive Neuroscience, Tohoku University Graduate School of Medicine, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Baba
authors.forename: Shigenori
authors.initials: S
authors.lastname: Kanno
authors.forename: Tomomi
authors.initials: T
authors.lastname: Shijo
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Nishio
authors.forename: Osamu
authors.initials: O
authors.lastname: Iizuka
authors.forename: Naoto
authors.initials: N
authors.lastname: Kamimura
authors.forename: Tomonori
authors.initials: T
authors.lastname: Ishii
authors.forename: Etsuro
authors.initials: E
authors.lastname: Mori
mesh_terms: D000368:Aged; D003337:Corpus Callosum / Q000473:pathology*; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008279:Magnetic Resonance Imaging; D008297:Male; D008590:Meningoencephalitis / Q000150:complications* / Q000188:drug therapy; D011081:Polychondritis, Relapsing / Q000150:complications* / Q000188:drug therapy; D013577:Syndrome
chemical_list: D007166:Immunosuppressive Agents