title: Disease vectors in the era of next generation sequencing.
abstract: Almost 20 % of all infectious human diseases are vector borne and, together, are responsible for over one million deaths per annum. Over the past decade, the decreasing costs of massively parallel sequencing technologies have facilitated the agnostic interrogation of insect vector genomes, giving medical entomologists access to an ever-expanding volume of high-quality genomic and transcriptomic data. In this review, we highlight how genomics resources have provided new insights into the physiology, behavior, and evolution of human disease vectors within the context of the global health landscape.
authors.affiliation: Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.
authors.forename: David C
authors.initials: DC
authors.lastname: Rinker
authors.affiliation: Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA.
authors.forename: R Jason
authors.initials: RJ
authors.lastname: Pitts
authors.affiliation: Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, USA. l.zwiebel@vanderbilt.edu.|Department of Pharmacology, Vanderbilt Brain Institute, Program in Developmental Biology, and Institutes of Chemical Biology and Global Health, Vanderbilt University Medical Center, Nashville, Tennessee, USA. l.zwiebel@vanderbilt.edu.
authors.forename: Laurence J
authors.initials: LJ
authors.lastname: Zwiebel
mesh_terms: D000818:Animals; D003141:Communicable Diseases / Q000235:genetics* / Q000635:transmission; D019143:Evolution, Molecular; D049750:Genome, Insect / Q000235:genetics; D023281:Genomics; D059014:High-Throughput Nucleotide Sequencing; D006801:Humans; D007303:Insect Vectors / Q000235:genetics*; D017422:Sequence Analysis, DNA