title: Scedosporium apiospermum as a rare cause of central skull base osteomyelitis.
abstract: We report a case of Scedosporium apiospermum mold causing ear infection, central skull base osteomyelitis and finally, occlusion of carotid artery in a 48-year-old diabetic man. The exact diagnosis was established and the severity of the disease understood several months after the onset of symptoms. Despite of appropriate antifungal therapy, and repeated surgical and otological procedures, the infection progressed to fatal cerebral infarction.
authors.affiliation: Department of Infectious Diseases, Division of Medicine, Turku University Hospital, Turku, Finland; Faculty of Medicine, Turku University, Turku, Finland.
authors.forename: Päivi
authors.initials: P
authors.lastname: Jalava-Karvinen
authors.affiliation: Department of Emergency Radiology, Medical Imaging Center of Southwest Finland, Turku University Hospital, Turku, Finland.
authors.forename: Mikko
authors.initials: M
authors.lastname: Nyman
authors.affiliation: Department of Pathology, Turku University Hospital, Turku, Finland; Faculty of Medicine, Turku University, Turku, Finland.
authors.forename: Maria
authors.initials: M
authors.lastname: Gardberg
authors.affiliation: Department of Clinical Microbiology, Turku University Hospital, Turku, Finland.
authors.forename: Inka
authors.initials: I
authors.lastname: Harju
authors.affiliation: Department of Infectious Diseases, Division of Medicine, Turku University Hospital, Turku, Finland; Faculty of Medicine, Turku University, Turku, Finland.
authors.forename: Ulla
authors.initials: U
authors.lastname: Hohenthal
authors.affiliation: Department of Infectious Diseases, Division of Medicine, Turku University Hospital, Turku, Finland; Faculty of Medicine, Turku University, Turku, Finland.
authors.forename: Jarmo
authors.initials: J
authors.lastname: Oksi
keywords: Central skull base osteomyelitis; Mold infection; Scedosporium apiospermum