title: Improving the antioxidant activity and enriching salvianolic acids by the fermentation of Salvia miltiorrhizae with Geomyces luteus.
abstract: The antioxidant activities and total phenolic content of fermented Salvia miltiorrhiza with fungus Geomyces luteus were investigated. The results revealed that G. luteus fermentation could significantly improve the antioxidant activity and total phenolic content of S. miltiorrhiza. The main antioxidant constituents were characterized by spectroscopic analysis as salvianolic acids. High-performance liquid chromatography (HPLC) quantification also showed the enhanced content of salvianolic acid B after fermentation. The present study suggests that G. luteus fermentations are effective in the S. miltiorrhiza salvianolic acids' enrichment process.
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Xing
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors.forename: Le
authors.initials: L
authors.lastname: Cai
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors.forename: Tian-Peng
authors.initials: TP
authors.lastname: Yin
authors.affiliation: Department of Pharmaceutical Sciences, Zhuhai Campus of Zunyi Medical University, Zhuhai 519041, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Yu
authors.affiliation: Department of Pharmaceutical Sciences, Zhuhai Campus of Zunyi Medical University, Zhuhai 519041, China.
authors.forename: Ya-Rong
authors.initials: YR
authors.lastname: Wang
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China.
authors.forename: Zhong-Tao
authors.initials: ZT
authors.lastname: Ding
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D000975:Antioxidants / Q000737:chemistry*; D001203:Ascomycota / Q000378:metabolism*; D001572:Benzofurans / Q000737:chemistry; D001713:Biphenyl Compounds / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D004365:Drugs, Chinese Herbal / Q000737:chemistry; D005285:Fermentation; D010636:Phenols / Q000737:chemistry; D010851:Picrates / Q000737:chemistry; D059808:Polyphenols / Q000737:chemistry*; D027561:Salvia miltiorrhiza / Q000737:chemistry*; D013056:Spectrophotometry, Ultraviolet; D017550:Spectroscopy, Fourier Transform Infrared; D053630:Depsides
chemical_list: D000475:Alkenes; D000975:Antioxidants; D001572:Benzofurans; D001713:Biphenyl Compounds; D004365:Drugs, Chinese Herbal; D010636:Phenols; D010851:Picrates; D059808:Polyphenols; C568740:salvianolic acid; C076944:salvianolic acid B; D053630:Depsides; C004931:1,1-diphenyl-2-picrylhydrazyl
keywords: Antioxidant; Fermentation; Geomyces luteus; Salvia miltiorrhiza; Salvianolic acids