title: Recurrence of graft steatosis after liver transplantation for cryptogenic cirrhosis in recently commenced liver transplant program.
abstract: Non-alcoholic fatty liver disease (NAFLD) seems to recur in at least one third of patients transplanted for non-alcoholic steatohepatitis (NASH)-related cirrhosis. While, NASH recurrence does not seem to affect overall graft and patient survival up to 10 years, cardiovascular and infection-related morbidity and mortality seem to be increased in these patients. This report looks at the graft histology in patients who were transplanted for NASH-related cirrhosis after short-term follow up. We report a high prevalence of recurrent NAFLD in liver grafts post-transplant among five patients. The degree of steatosis noted among the recipients is alarming.
authors.affiliation: Hepato-Pancreatico-Biliary and Liver Transplant Unit Ragama, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka. rohansiriwardana@yahoo.com.
authors.forename: Rohan C
authors.initials: RC
authors.lastname: Siriwardana
authors.affiliation: Hepato-Pancreatico-Biliary and Liver Transplant Unit Ragama, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
authors.forename: Madunil Anuk
authors.initials: MA
authors.lastname: Niriella
authors.affiliation: Hepato-Pancreatico-Biliary and Liver Transplant Unit Ragama, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
authors.forename: Anuradha Supun
authors.initials: AS
authors.lastname: Dassanayake
authors.affiliation: Hepato-Pancreatico-Biliary and Liver Transplant Unit Ragama, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
authors.forename: Chandika Anuradha Habarakada
authors.initials: CA
authors.lastname: Liyanage
authors.affiliation: Hepato-Pancreatico-Biliary and Liver Transplant Unit Ragama, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
authors.forename: Bhagya
authors.initials: B
authors.lastname: Gunetilleke
authors.affiliation: Hepato-Pancreatico-Biliary and Liver Transplant Unit Ragama, Faculty of Medicine, University of Kelaniya, Kelaniya, Sri Lanka.
authors.forename: Hithanadura Janaka
authors.initials: HJ
authors.lastname: de Silva
mesh_terms: D005500:Follow-Up Studies; D006801:Humans; D008103:Liver Cirrhosis / Q000209:etiology* / Q000601:surgery*; D016031:Liver Transplantation; D008297:Male; D008875:Middle Aged; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications* / Q000453:epidemiology*; D015995:Prevalence; D012008:Recurrence
keywords: Hepatic steatosis; Liver transplantation; Metabolic syndrome; Non-alcoholic fatty liver disease