title: In Situimmunization by bispecific antibody targeted T cell therapy in breast cancer.
abstract: Metastatic breast cancer remains an incurable disease. Most patients experience objective treatment responses associated with palliation of symptoms; however, progression inevitably occurs. Thus, there is an urgent need for innovative therapeutic strategies that may halt disease progression. Adoptive T-cell therapy is a potent and promising treatment option with the potential to harness the intrinsic antitumor power of the immune system and provide long-term immunity against cancer.
authors.affiliation: Department of Oncology; Wayne State University, and Karmanos Cancer Institute ; Detroit, MI, USA.
authors.forename: Archana
authors.initials: A
authors.lastname: Thakur
authors.affiliation: Department of Oncology; Wayne State University, and Karmanos Cancer Institute; Detroit, MI, USA; Department of Medicine; Wayne State University, and Karmanos Cancer Institute; Detroit, MI, USA; Department of Pediatrics; Wayne State University, and Karmanos Cancer Institute; Detroit, MI, USA; Department of Immunology and Microbiology; Wayne State University and Karmanos Cancer Institute; Detroit, MI, USA.
authors.forename: Lawrence G
authors.initials: LG
authors.lastname: Lum
keywords: adaptive T cell therapy; bispecific antibody; breast cancer; immunotherapy