title: Concurrent Therapy with a Low-carbohydrate Diet and Miglitol Remarkably Improved the Postprandial Blood Glucose and Insulin Levels in a Patient with Reactive Hypoglycemia due to Late Dumping Syndrome.
abstract: Reactive hypoglycemia induced by late dumping syndrome is often observed after gastrectomy. However, no effective therapy has yet been fully established. We herein describe a case in which concurrent therapy with a low-carbohydrate diet using low-glycemic-index food and an alpha-glucosidase inhibitor, miglitol, very effectively ameliorated the postprandial fluctuations in the blood glucose and plasma insulin levels in a patient with reactive hypoglycemia due to late dumping syndrome following total gastrectomy. The administration of miglitol under a low-carbohydrate diet using low-glycemic-index food may therefore be an ideal treatment for reactive hypoglycemia due to late dumping syndrome.
authors.affiliation: Division of Diabetes and Endocrinology, Department of Internal Medicine, Chibune General Hospital, Japan.
authors.forename: Sachie
authors.initials: S
authors.lastname: Hirose
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Iwahashi
authors.forename: Akane
authors.initials: A
authors.lastname: Seo
authors.forename: Michitaka
authors.initials: M
authors.lastname: Sumiyoshi
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Takahashi
authors.forename: Yoshikazu
authors.initials: Y
authors.lastname: Tamori
mesh_terms: D017485:1-Deoxynojirimycin / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000368:Aged; D001786:Blood Glucose / Q000187:drug effects; D003131:Combined Modality Therapy; D050528:Diet, Carbohydrate-Restricted; D004377:Dumping Syndrome / Q000150:complications*; D005951:Glucose Tolerance Test; D065089:Glycoside Hydrolase Inhibitors / Q000627:therapeutic use; D006801:Humans; D007003:Hypoglycemia / Q000097:blood / Q000209:etiology / Q000628:therapy*; D007004:Hypoglycemic Agents / Q000627:therapeutic use*; D007328:Insulin / Q000097:blood; D008297:Male; D019518:Postprandial Period / Q000502:physiology
chemical_list: D001786:Blood Glucose; D065089:Glycoside Hydrolase Inhibitors; D007004:Hypoglycemic Agents; D007328:Insulin; C045621:miglitol; D017485:1-Deoxynojirimycin