title: Metabolic Syndrome and Sexual Function in Postmenopausal Women.
abstract: BACKGROUND
  Limited literature suggests that sexual dysfunction in women covaries with the metabolic syndrome. This study examined the association of sexual function with metabolic syndrome and cardiovascular disease in healthy older women.
  
  
  METHODS
  There were 376 postmenopausal, community-dwelling women from the Rancho Bernardo Study (mean baseline age = 73 years) that completed a clinic visit during 1999-2002 and returned the Female Sexual Function Index (FSFI) questionnaire mailed in 2002.
  
  
  RESULTS
  Thirty-nine percent reported being sexually active; 41.5% met a diagnosis of metabolic syndrome. The number of metabolic syndrome components was strongly associated with decreased sexual activity, desire, and low sexual satisfaction. Waist girth, diabetes, and hypertension were associated with decreased sexual activity. Elevated triglycerides were associated with low desire. Among the cardiovascular endpoints, heart attack, coronary artery bypass, and angina were associated with decreased sexual activity, but not with sexual desire or satisfaction. Past diagnosis of heart failure, poor circulation, and stroke were not associated with sexual function. Sexually active women with metabolic syndrome met criteria for sexual dysfunction in desire, arousal, orgasm, and satisfaction domains. The FSFI Total Score did not differ significantly between sexually active and inactive women.
  
  
  CONCLUSIONS
  Metabolic syndrome was associated with decreased sexual activity, desire, and satisfaction in all women and with sexual dysfunction in most domains in sexually active women. Coronary artery disease was more prevalent in women with low sexual activity.
authors.affiliation: Division of General Internal Medicine, Department of Medicine, University of California, San Diego, La Jolla, California; Veterans Affairs San Diego Healthcare System, San Diego, California.
authors.forename: Susan E
authors.initials: SE
authors.lastname: Trompeter
authors.affiliation: Division of Epidemiology, Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California.
authors.forename: Ricki
authors.initials: R
authors.lastname: Bettencourt
authors.affiliation: Division of Epidemiology, Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, California. Electronic address: ebarrettconnor@ucsd.edu.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Barrett-Connor
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D002140:California / Q000453:epidemiology; D002318:Cardiovascular Diseases / Q000453:epidemiology*; D015897:Comorbidity; D005260:Female; D006304:Health Status; D006801:Humans; D007989:Libido / Q000502:physiology; D017533:Marital Status; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology*; D008875:Middle Aged; D017698:Postmenopause / Q000502:physiology / Q000523:psychology; D015995:Prevalence; D012725:Sexual Behavior / Q000502:physiology / Q000706:statistics & numerical data*; D012735:Sexual Dysfunction, Physiological / Q000453:epidemiology*; D020018:Sexual Dysfunctions, Psychological / Q000453:epidemiology*; D055105:Waist Circumference
keywords: FSFI; Female Sexual Function Index; Metabolic syndrome; Sexual dysfunction