title: Cell wall structure and biogenesis in Aspergillus species.
abstract: Aspergillus species are among the most important filamentous fungi from the viewpoints of industry, pathogenesis, and mycotoxin production. Fungal cells are exposed to a variety of environmental stimuli, including changes in osmolality, temperature, and pH, which create stresses that primarily act on fungal cell walls. In addition, fungal cell walls are the first interactions with host cells in either human or plants. Thus, understanding cell wall structure and the mechanism of their biogenesis is important for the industrial, medical, and agricultural fields. Here, we provide a systematic review of fungal cell wall structure and recent findings regarding the cell wall integrity signaling pathways in aspergilli. This accumulated knowledge will be useful for understanding and improving the use of industrial aspergilli fermentation processes as well as treatments for some fungal infections.
authors.affiliation: a ABE-project, New Industry Creation Hatchery Center , Tohoku University , Sendai , Japan.
authors.forename: Akira
authors.initials: A
authors.lastname: Yoshimi
authors.affiliation: b Laboratory of Applied Microbiology, Department of Microbial Biotechnology, Graduate School of Agricultural Sciences , Tohoku University , Sendai , Japan.
authors.forename: Ken
authors.initials: K
authors.lastname: Miyazawa
authors.affiliation: a ABE-project, New Industry Creation Hatchery Center , Tohoku University , Sendai , Japan.|b Laboratory of Applied Microbiology, Department of Microbial Biotechnology, Graduate School of Agricultural Sciences , Tohoku University , Sendai , Japan.
authors.forename: Keietsu
authors.initials: K
authors.lastname: Abe
mesh_terms: D001230:Aspergillus / Q000737:chemistry / Q000254:growth & development / Q000378:metabolism*; D002473:Cell Wall / Q000737:chemistry / Q000378:metabolism*; D005285:Fermentation; D006801:Humans; D009181:Mycoses / Q000188:drug therapy / Q000382:microbiology*; D010944:Plants / Q000382:microbiology; D011134:Polysaccharides / Q000737:chemistry / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics
chemical_list: D011134:Polysaccharides
keywords: Aspergillus species; cell wall; glucans; polysaccharides; signal transduction