title: Long-Term Clinical and Electroencephalography (EEG) Consequences of Idiopathic Partial Epilepsies.
abstract: BACKGROUND Idiopathic partial epilepsies of childhood (IPE) affect a considerable proportion of children. Three main electroclinical syndromes of IPE are the Benign Childhood Epilepsy with Centro-temporal Spikes (BECTS), Panayiotopoulos Syndrome (PS), and Childhood Epilepsy with Occipital Paroxysms (CEOP). In this study we investigated the long-term prognosis of patients with IPE and discussed the semiological and electroencephalography (EEG) data in terms of syndromic characteristics. MATERIAL AND METHODS This study included a group of consecutive patients with IPE who had been followed since 1990. Demographic and clinical variables were investigated. Patients were divided into 3 groups - A: Cases suitable for a single IPE (BECTS, PS and CEOP); B: cases with intermediate characteristics within IPEs; and C: cases with both IPE and IGE characteristics. Long-term data regarding the individual seizure types and EEG findings were re-evaluated. RESULTS A total of 61 patients were included in the study. Mean follow-up duration was 7.8 ± 4.50 years. The mean age at onset of seizures was 7.7 years. There were 40 patients in group A 40, 14 in group B, and 7 in group C. Seizure and EEG characteristics were also explored independently from the syndromic approach. Incidence of autonomic seizures is considerably high at 2-5 years and incidence of oromotor seizures is high at age 9-11 years. The EEG is most abnormal at 6-8 years. The vast majority (86%) of epileptic activity (EA) with parietooccipital is present at 2-5 years, whereas EA with fronto-temporal or multiple sites become more abundant between ages 6 and 11. CONCLUSIONS Results of the present study provide support for the age-related characteristics of the seizures and EEGs in IPE syndromes. Acknowledgement of those phenomena may improve the management of IPEs and give a better estimate of the future consequences.
authors.affiliation: Department of Neurology and Neurophysiology, Fatih Sultan Mehmet Training and Research Hospital, İstanbul, Turkey.
authors.forename: Nimet
authors.initials: N
authors.lastname: Dörtcan
authors.affiliation: Department of Neurology, Bakırkoy Psychiatric and Neurological Diseases Training and Research Hospital, İstanbul, Turkey.
authors.forename: Betul
authors.initials: B
authors.lastname: Tekin Guveli
authors.affiliation: Department of Child Neurology, Special Child Neurology Clinic, İstanbul, Turkey.
authors.forename: Aysin
authors.initials: A
authors.lastname: Dervent
mesh_terms: D000293:Adolescent; D002648:Child; D002675:Child, Preschool; D003710:Demography; D004569:Electroencephalography / Q000379:methods*; D019305:Epilepsy, Rolandic / Q000175:diagnosis*; D005260:Female; D006801:Humans; D008297:Male; D013997:Time Factors