title: Eligibility Criteria for Deep Brain Stimulation in Parkinson's Disease, Tremor, and Dystonia.
abstract: In this review, the available evidence to guide clinicians regarding eligibility for deep brain stimulation (DBS) in the main conditions in which these forms of therapy are generally indicated-Parkinson's disease (PD), tremor, and dystonia-is presented. In general, the literature shows that DBS is effective for PD, essential tremor, and idiopathic dystonia. In these cases, key points in patient selection must include the level of disability and inability to manage symptoms using the best available medical therapy. Results are, however, still not optimal when dealing with other aetiologies, such as secondary tremors and symptomatic dystonia. Also, in PD, issues such as age and neuropsychiatric profile are still debatable parameters. Overall, currently available literature is able to guide physicians on basic aspects of patient selection and indications for DBS; however, a few points are still debatable and controversial. These issues should be refined and clarified in future studies.
authors.affiliation: 1Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario,Canada.
authors.forename: Renato P
authors.initials: RP
authors.lastname: Munhoz
authors.affiliation: 1Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario,Canada.
authors.forename: Marina
authors.initials: M
authors.lastname: Picillo
authors.affiliation: 1Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario,Canada.
authors.forename: Susan H
authors.initials: SH
authors.lastname: Fox
authors.affiliation: 1Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario,Canada.
authors.forename: Veronica
authors.initials: V
authors.lastname: Bruno
authors.affiliation: 3André-Barbeau Movement Disorders Unit Service of Neurology,Centre Hospitalier de l'Université de Montréal and Department of Medicine,Université de Montréal,Montréal,Québec,Canada.
authors.forename: Michel
authors.initials: M
authors.lastname: Panisset
authors.affiliation: 4Division of Neurosurgery,University of British Columbia,Vancouver,British Columbia,Canada.
authors.forename: Christopher R
authors.initials: CR
authors.lastname: Honey
authors.affiliation: 1Morton and Gloria Shulman Movement Disorders Centre and the Edmond J. Safra Program in Parkinson's Disease,Toronto Western Hospital,University Health Network,Toronto,Ontario,Canada.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Fasano
mesh_terms: D046690:Deep Brain Stimulation / Q000379:methods* / Q000592:standards*; D004421:Dystonia / Q000628:therapy*; D006801:Humans; D010300:Parkinson Disease / Q000628:therapy*; D014202:Tremor / Q000628:therapy*
keywords: Parkinson’s disease; deep brain stimulation; dystonia; essential tremor; movement disorders; surgery; tremor