title: Brown-McLean syndrome: the role of iridodonesis.
abstract: OBJECTIVE
  The aim of this study was to report a case series of Brown-McLean syndrome (BMS).
  
  
  METHODS
  The charts of 28 patients with BMS at Ramathibodi and Rutnin Hospital from 1981 to 2015 were reviewed.
  
  
  RESULTS
  BMS is a rare condition with corneal edema involving the peripheral cornea with orange-brown pigment deposition underlying the edematous area. The edema typically starts inferiorly and advances circumferentially to superior cornea. Central cornea remains clear in most patients. We report 28 patients with BMS that occurred either spontaneously or after various intraocular procedures. Ultrasound biomicroscopy was performed to demonstrate the iridocorneal relationship.
  
  
  CONCLUSIONS
  Iridocorneal relationship from the ultrasound biomicroscopy study in four patients did not support previous hypothesis about the role of iridodonesis impact on corneal endothelium. Patients with BMS can rarely progress to corneal decompensation; however, they should be periodically monitored and made aware of early clinical signs of their complications.
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Yanin
authors.initials: Y
authors.lastname: Suwan
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Chaiwat
authors.initials: C
authors.lastname: Teekhasaenee
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Kaevalin
authors.initials: K
authors.lastname: Lekhanont
authors.affiliation: Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Wasu
authors.initials: W
authors.lastname: Supakontanasan
keywords: Brown–McLean syndrome; corneal decompensation; marginal corneal edema; peripheral corneal edema