title: Imaging Spectrum and Pitfalls of (11)C-Methionine Positron Emission Tomography in a Series of Patients with Intracranial Lesions.
abstract: (11)C-methionine (Met) positron emission tomography (PET) is one of the most commonly used PET tracers for evaluating brain tumors. However, few reports have described tips and pitfalls of (11)C-Met PET for general practitioners. Physiological (11)C-Met uptake, anatomical variations, vascular disorders, non-tumorous lesions such as inflammation or dysplasia, benign brain tumors and patient condition during (11)C-Met PET examination can potentially affect the image interpretation and cause false positives and negatives. These pitfalls in the interpretation of (11)C-Met PET images are important for not only nuclear medicine physicians but also general radiologists. Familiarity with the spectrum and pitfalls of (11)C-Met images could help prevent unfavorable clinical results caused by misdiagnoses.
authors.affiliation: Department of Radiology, Tokyo Metropolitan Geriatric Hospital and Institute of Gerontology, Tokyo 173-0015, Japan.
authors.forename: Kimiteru
authors.initials: K
authors.lastname: Ito
authors.affiliation: Integrative Brain Imaging Center, National Center of Neurology and Psychiatry, Tokyo 187-8551, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuda
authors.affiliation: Division of Nuclear Medicine, National Center for Global Health and Medicine, Tokyo 162-8655, Japan.
authors.forename: Kazoo
authors.initials: K
authors.lastname: Kubota
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D002250:Carbon Radioisotopes / Q000737:chemistry; D002648:Child; D002675:Child, Preschool; D005260:Female; D005910:Glioma / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008297:Male; D008715:Methionine / Q000737:chemistry*; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local; D049268:Positron-Emission Tomography; D014652:Vascular Diseases / Q000000981:diagnostic imaging* / Q000473:pathology; D055815:Young Adult
chemical_list: D002250:Carbon Radioisotopes; D008715:Methionine
keywords: Brain tumors; Inflammation; Methionine; Positron-emission tomography; Vascular diseases