title: [Contact lens-associated Paecilomyces lilacinus keratitis].
abstract: We present the case of a 23-year-old otherwise healthy female patient with contact lens-associated Paecilomyces lilacinus keratitis. The clinical findings stabilized after initial local antimycotic and antibacterial treatment; however, in the further course of local therapy an extensive relapse occurred which required treatment by perforating keratoplasty à chaud due to a penetrating corneal ulcer. The patient responded well to subsequent treatment with systemic and local antimycotic medication. After a few months HLA-matched keratoplasty was performed. During the follow-up time of 14 months there were no signs of recurrence of the infection.
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Münster, Domagkstr. 15, 48149, Münster, Deutschland. natasa.mihailovic@ukmuenster.de.
authors.forename: N
authors.initials: N
authors.lastname: Mihailovic
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Münster, Domagkstr. 15, 48149, Münster, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Alnawaiseh
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Münster, Domagkstr. 15, 48149, Münster, Deutschland.
authors.forename: L
authors.initials: L
authors.lastname: Zumhagen
authors.affiliation: Klinik für Augenheilkunde, Universitätsklinikum Münster, Domagkstr. 15, 48149, Münster, Deutschland.
authors.forename: N
authors.initials: N
authors.lastname: Eter
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D003261:Contact Lenses / Q000009:adverse effects* / Q000382:microbiology*; D003937:Diagnosis, Differential; D015821:Eye Infections, Fungal / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology*; D005260:Female; D006801:Humans; D007634:Keratitis / Q000188:drug therapy / Q000209:etiology* / Q000382:microbiology*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000935:Antifungal Agents
keywords: Contact lens-associated keratitis; Corneal ulcer; Fungal keratitis; Paecilomyces lilacinus; Voriconazole