title: Antisynthetase Syndrome: A Rare Cause for ILD.
abstract: Anti-Synthetase Syndrome (ASS) is a rare autoimmune disorder characterized by Interstitial Lung Disease (ILD), inflammatory myositis, fever, Raynaud's phenomenon, mechanic's hand, and inflammatory polyarthritis in the setting of antibodies against amino acyl-transfer RNA synthetases, with anti-Jo-1 antibody being the most common. It can sometimes present as interstitial lung disease without any other expression of the syndrome. Clinical and radiological features can be similar to atypical pneumonia and could be a challenge to diagnose at an early stage. Prognosis is generally poor, especially when there is associated ILD and delay in diagnosis can lead to increase in morbidity due to progression of pulmonary involvement. We report a patient of ASS presenting with ILD, diagnosed early and treated successfully with immunosupression.
authors.affiliation: Associate Professor, Department of Respiratory Medicine, MS Ramaiah Medical College , Bangalore, India .
authors.forename: Hj Gayathri
authors.initials: HG
authors.lastname: Devi
authors.affiliation: Resident, Department of Respiratory Medicine, MS Ramaiah Medical College , Bangalore, India .
authors.forename: Md Majeed
authors.initials: MM
authors.lastname: Pasha
authors.affiliation: Resident, Department of Respiratory Medicine, MS Ramaiah Medical College , Bangalore, India .
authors.forename: Mantha Sathya
authors.initials: MS
authors.lastname: Padmaja
authors.affiliation: Resident, Department of Respiratory Medicine, MS Ramaiah Medical College , Bangalore, India .
authors.forename: Sujith
authors.initials: S
authors.lastname: Halappa
keywords: Anti-jo-1; Cryptogenic; Organizing; Pneumonia