title: ETS transcription factors in embryonic vascular development.
abstract: At least thirteen ETS-domain transcription factors are expressed during embryonic hematopoietic or vascular development and potentially function in the formation and maintenance of the embryonic vasculature or blood lineages. This review summarizes our current understanding of the specific roles played by ETS factors in vasculogenesis and angiogenesis and the implications of functional redundancies between them.
authors.affiliation: Department of Biochemistry and Molecular Biology, Wright State University, 3640 Colonel Glenn Hwy., Dayton, OH, 45435, USA.|Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Craig
authors.affiliation: Division of Developmental Biology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA. Saulius.Sumanas@cchmc.org.
authors.forename: Saulius
authors.initials: S
authors.lastname: Sumanas
mesh_terms: D000818:Animals; D001808:Blood Vessels / Q000196:embryology*; D047108:Embryonic Development / Q000235:genetics / Q000502:physiology; D018507:Gene Expression Regulation, Developmental; D055785:Gene Knockdown Techniques; D006410:Hematopoiesis / Q000235:genetics / Q000502:physiology; D006801:Humans; D018919:Neovascularization, Physiologic / Q000235:genetics; D050783:Proto-Oncogene Proteins c-ets / Q000037:antagonists & inhibitors / Q000235:genetics / Q000502:physiology*
chemical_list: D050783:Proto-Oncogene Proteins c-ets
keywords: Angiogenesis; ETS transcription factor; Vasculogenesis