title: CT perfusion imaging of the stomach: a quantitative analysis according to different degrees of adenocarcinoma cell differentiation.
abstract: OBJECTIVE
  To evaluate clinical usefulness of computed tomography perfusion imaging (CTPI) in gastric cancer.
  
  
  METHODS
  Twenty subjects without gastric diseases (control group) and fifty patients with gastric cancer were studied prospectively using CTPI examinations. Four perfusion parameter values, i.e., blood flow (BF), blood volume (BV), mean transit time, and permeability surface (PS), were calculated. The gastric cancer group was divided into three groups: well differentiated, moderately differentiated, and poorly differentiated gastric adenocarcinoma.
  
  
  RESULTS
  Comparing the three groups, differences between the well-differentiated group and the moderately differentiated group or the poorly differentiated group were all statistically significant for BF, BV, and PS.
  
  
  CONCLUSIONS
  The BF, BV, and PS values could serve as indicators of the degree of malignancy of gastric cancer.
authors.affiliation: Department of Radiology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Sun
authors.initials: S
authors.lastname: Zongqiong
authors.affiliation: Department of Radiology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Li
authors.initials: L
authors.lastname: Xiaohong
authors.affiliation: Department of Radiology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Cai
authors.initials: C
authors.lastname: Wei
authors.affiliation: Department of Radiology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Zhou
authors.initials: Z
authors.lastname: Jiangfeng
authors.affiliation: Department of Radiology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Ge
authors.initials: G
authors.lastname: Yuxi
authors.affiliation: Department of Surgical Gastroenterology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Xie
authors.initials: X
authors.lastname: Zhihui
authors.affiliation: Department of Pathology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Linfang
authors.affiliation: Department of Pathology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China.
authors.forename: Pu
authors.initials: P
authors.lastname: Yong
authors.affiliation: Department of Radiology, Affiliated Hospital of Jiangnan University, The Forth People's Hospital of Wuxi City, Wuxi, 214062, China. Electronic address: qiong953785@163.com.
authors.forename: Yan
authors.initials: Y
authors.lastname: Gen
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002454:Cell Differentiation; D003287:Contrast Media / Q000008:administration & dosage; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010477:Perfusion; D011446:Prospective Studies; D013270:Stomach / Q000000981:diagnostic imaging* / Q000473:pathology; D013274:Stomach Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media
keywords: Cell differentiation; Computed tomography; Gastric cancer; Perfusion