title: McKittrick-Wheelock syndrome: a rare case report of acute renal failure.
abstract: Giant tubular-villous adenoma of the rectum can determine secretory diarrhea, associated with a depleting syndrome of prerenal acute renal failure, hyponatremia, hypokalemia and hypoproteinemia. These symptoms are known as the McKittrick-Wheelock syndrome, and there are about 50 cases reported in literature. We present the case of a 59-year-old woman presented to our emergency department with abdominal pain, prerenal azotemia, and electrolyte disturbances with a background of chronic diarrhea, caused by a giant rectal tumor. Conservative therapy initially improved and normalized renal function, and made surgical resection of the tumor possible.
authors.affiliation: Department of Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Surgery, Regional Institute of Gastroenterology and Hepatology Prof. O. Fodor, Cluj-Napoca, Romania.
authors.forename: Emil Ioan
authors.initials: EI
authors.lastname: Mois
authors.affiliation: Department of Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Surgery, Regional Institute of Gastroenterology and Hepatology Prof. O. Fodor, Cluj-Napoca, Romania.
authors.forename: Florin
authors.initials: F
authors.lastname: Graur
authors.affiliation: Department of Pathology, Regional Institute of Gastroenterology and Hepatology Prof. O. Fodor, Cluj-Napoca, Romania.
authors.forename: Roxana
authors.initials: R
authors.lastname: Sechel
authors.affiliation: Department of Surgery, Iuliu Hatieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania; Department of Surgery, Regional Institute of Gastroenterology and Hepatology Prof. O. Fodor, Cluj-Napoca, Romania.
authors.forename: Nadim
authors.initials: N
authors.lastname: Al-Hajjar
keywords: hydro-electrolytic disturbances; renal failure; tubular-villous adenoma