title: Epidemiology of Endometriosis in France: A Large, Nation-Wide Study Based on Hospital Discharge Data.
abstract: We aimed to assess the prevalence of hospitalization for endometriosis in the general population in France and in each French region and to describe temporal trends, rehospitalization rates, and prevalence of the different types of endometriosis. The analyses were carried out on French hospital discharge data and covered the period 2008-2012 and a population of 14,239,197 women of childbearing age. In this population, the prevalence of hospitalization for endometriosis was 0.9%, ranging from 0.4% to 1.6% between regions. Endometriosis affected 1.5% of hospitalized women of childbearing age, ranging from 1.0% to 2.4% between regions. The number of patients hospitalized for endometriosis significantly increased over the study period (p < 0.01). Of these, 4.2% were rehospitalized at least once at one year: ranging from 2.7% to 6.3% between regions. The cumulative rehospitalization rate at 3 years was 6.9%. The types of endometriosis according to the procedures performed were as follows: ovarian (40-50%), peritoneal (20-30%), intestinal (10-20%), and ureteral or bladder (<10%), with significant differences between regions. This is the first detailed epidemiological study of endometriosis in France. Further studies are needed to assess the reasons for the increasing prevalence of endometriosis and for the significant differences in regional prevalence of this disease.
authors.affiliation: Centre d'Etudes Périnatales de l'Océan Indien (EA 7388), CHU de la Réunion, Site Sud, 97448 Saint-Pierre, France; Department of Gynecology and Obstetrics, Hospital Felix Guyon, CHU de la Reunion, Site Nord, 9740 Saint Denis, France.
authors.forename: Peter
authors.initials: P
authors.lastname: von Theobald
authors.affiliation: CHRU Dijon, Service de Biostatistique et d'Informatique Médicale (DIM) and Université de Bourgogne Franche-Comté, 21000 Dijon, France.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Cottenet
authors.affiliation: Centre d'Etudes Périnatales de l'Océan Indien (EA 7388), CHU de la Réunion, Site Sud, 97448 Saint-Pierre, France; Néonatologie, Réanimation Néonatale et Pédiatrique, CHU de la Réunion, Site Sud, 97448 Saint-Pierre, France.
authors.forename: Silvia
authors.initials: S
authors.lastname: Iacobelli
authors.affiliation: CHRU Dijon, Service de Biostatistique et d'Informatique Médicale (DIM) and Université de Bourgogne Franche-Comté, 21000 Dijon, France; INSERM, CIC 1432 and Dijon University Hospital, Clinical Investigation Center, Clinical Epidemiology/Clinical Trials Unit, 21000 Dijon, France; INSERM UMR 1181 "Biostatistics, Biomathematics, Pharmacoepidemiology and Infectious Diseases" (B2PHI), University Bourgogne Franche-Comté, 21000 Dijon, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Quantin
mesh_terms: D000293:Adolescent; D000328:Adult; D003625:Data Collection; D004715:Endometriosis / Q000453:epidemiology*; D005260:Female; D005602:France / Q000453:epidemiology; D005843:Geography; D006760:Hospitalization; D006801:Humans; D008875:Middle Aged; D015233:Models, Statistical; D010351:Patient Discharge; D015995:Prevalence; D012307:Risk Factors; D013997:Time Factors; D055815:Young Adult