title: Fiber in Diet Is Associated with Improvement of Glycated Hemoglobin and Lipid Profile in Mexican Patients with Type 2 Diabetes.
abstract: Objective. To assess the association of dietary fiber on current everyday diet and other dietary components with glycated hemoglobin levels (HbA1c), glucose, lipids profile, and body weight body weight, in patients with type 2 diabetes. Methods. A cross-sectional survey of 395 patients with type 2 diabetes was performed. HbA1c, fasting glucose, triglycerides, and lipids profile were measured. Weight, waist circumference, blood pressure, and body composition were measured. Everyday diet with a semiquantitative food frequency questionnaire was evaluated. ANOVA, Kruskal-Wallis, chi-square tests and multivariate logistic regression were used in statistical analysis. Results. Higher fiber intake was associated with a low HbA1c, high HDL-c levels, low weight, and waist circumference. The highest tertile of calories consumption was associated with a higher fasting glucose level and weight. The highest tertile of carbohydrate consumption was associated with a lower weight. The lowest tertile of total fat and saturated fat was associated with the highest tertile of HDL-c levels, and lower saturated fat intake was associated with lower weight (p < 0.05). Conclusions. A higher content of fiber in the diet reduces HbA1c and triglycerides, while improving HDL-c levels. Increasing fiber consumption while lowering calorie consumption seems to be an appropriate strategy to reduce body weight and promote blood glucose control.
authors.affiliation: Unidad de Investigación en Epidemiología Clínica, Hospital "Carlos MacGregor Sánchez Navarro", Instituto Mexicano del Seguro Social, Avenida Gabriel Mancera No. 222, Colonia del Valle, Delegación Bénito Juárez, 03100 Ciudad de México, Mexico.
authors.forename: Lubia
authors.initials: L
authors.lastname: Velázquez-López
authors.affiliation: Departamento de Salud Pública, Facultad de Medicina, Universidad Nacional Autónoma de México, 6 Piso, Edificio B, Circuito Interior, Ciudad Universitaria, Avenida Universidad 3000, Ciudad de México, Mexico.
authors.forename: Abril Violeta
authors.initials: AV
authors.lastname: Muñoz-Torres
authors.affiliation: Departamento de Investigación, Instituto Nacional de Geriatría, Periférico sur No. 2767, Colonia San Jerónimo Lídice, Delegación Magdalena Contreras, 10200 Ciudad de México, Mexico.
authors.forename: Carmen
authors.initials: C
authors.lastname: García-Peña
authors.affiliation: Unidad de Investigación Médica en Nutrición, Hospital de Pediatría, Centro Medico Nacional "Siglo XXI", Instituto Mexicano del Seguro Social, Avenida Cuauhtémoc 300, Colonia Doctores, Delegación Cuauhtemoc, 06720 Ciudad de México, Mexico.
authors.forename: Mardia
authors.initials: M
authors.lastname: López-Alarcón
authors.affiliation: Unidad de Investigación Científica de Endocrinología, Diabetes y Metabolismo, y de Enfermedades Metabólicas, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Avenida Cuauhtémoc 300, Colonia Doctores, Delegación Cuauhtemoc, 06720 Ciudad de México, Mexico.
authors.forename: Sergio
authors.initials: S
authors.lastname: Islas-Andrade
authors.affiliation: Unidad de Investigación en Epidemiología Clínica, Hospital "Carlos MacGregor Sánchez Navarro", Instituto Mexicano del Seguro Social, Avenida Gabriel Mancera No. 222, Colonia del Valle, Delegación Bénito Juárez, 03100 Ciudad de México, Mexico.
authors.forename: Jorge
authors.initials: J
authors.lastname: Escobedo-de la Peña
mesh_terms: D001786:Blood Glucose / Q000378:metabolism*; D001835:Body Weight; D008076:Cholesterol, HDL / Q000378:metabolism*; D008078:Cholesterol, LDL / Q000378:metabolism*; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000378:metabolism*; D004032:Diet; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D002149:Energy Intake; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism*; D006801:Humans; D016015:Logistic Models; D008297:Male; D008800:Mexico; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D014280:Triglycerides / Q000378:metabolism*
chemical_list: D001786:Blood Glucose; D008076:Cholesterol, HDL; D008078:Cholesterol, LDL; D004040:Dietary Carbohydrates; D004041:Dietary Fats; D004043:Dietary Fiber; D006442:Glycated Hemoglobin; D014280:Triglycerides; C517652:hemoglobin A1c protein, human