title: A water-soluble and retrievable ruthenium-based probe for colorimetric recognition of Hg(II) and Cys.
abstract: A new ruthenium-based complex 1 [(bis(4,4'-dimethylphosphonic-2,2'-bipyridine) dithiocyanato ruthenium (II))] was developed as a colorimetric probe for the detection of Hg(II) and Cys (Cysteine). The obtained compound 1 can give interconversional color changes upon the alternating addition of Hg(II) and Cys in 100% aqueous solution. The specific coordination between NCS groups with Hg(II) can lead to the formation of 1-Hg(2+) complex, which can induce a remarkable spectral changes of probe 1. Afterwards the formed 1-Hg(2+) complex can act as effective colorimetric sensor for Cys. Owing to the stronger binding affinity of sulfhydryl group to Hg(2+), Cys can extract Hg(2+) from 1-Hg(2+) complex resulting in the release of 1 and the revival of absorption profile of the probe 1. By introducing the hydrophilic phosphonic acid groups, the proposed probe exhibited excellent water solubility. The limits of detection (LODs) of the assay for Hg(2+) and Cys are calculated to be 15nM and 200nM, respectively.
authors.affiliation: Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, Henan, China.
authors.forename: Yali
authors.initials: Y
authors.lastname: Cui
authors.affiliation: Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, Henan, China. Electronic address: hao0736@163.com.
authors.forename: Yuanqiang
authors.initials: Y
authors.lastname: Hao
authors.affiliation: Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, Henan, China.
authors.forename: Yintang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, Henan, China.
authors.forename: Baoxia
authors.initials: B
authors.lastname: Liu
authors.affiliation: Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, Henan, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, Henan, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Qu
authors.affiliation: Institute of Environmental and Analytical Sciences, College of Chemistry and Chemical Engineering, Henan University, Kaifeng 475004, Henan, China. Electronic address: lideliang@henu.edu.cn.
authors.forename: Deliang
authors.initials: D
authors.lastname: Li
authors.affiliation: Henan Key Laboratory of Biomolecular Recognition and Sensing, College of Chemistry and Chemical Engineering, Shangqiu Normal University, Shangqiu 476000, Henan, China. Electronic address: xumaotian@sqnc.edu.cn.
authors.forename: Maotian
authors.initials: M
authors.lastname: Xu
keywords: Colorimetric probe; Cysteine; Mercury; Phosphonic group; Ruthenium