title: [Cancer as secondary immunodeficiency. Review].
abstract: Secondary immunodeficiencys, previously presented in immunocompetent individuals. The lack of primary or secondary response to the presence of a foreign antigen, in the case of infections is a sentinel data in the diagnosis of immunodeficiency (can be primary or secondary), in the case of a self antigen may generate the presence of Cancer. Cancer has shown an increase in the prevalence and incidence globally. Most current medical treatments in cancer are focused primarily on immunomodulatory actions (immunosuppression / immune stimulation or both). Knowledge of key concepts from the perspective of innate and acquired immunity lead to cancer development, engaging immune surveillance and escape mechanisms of this that contribute to better understand the origin, behavior and treatment of neoplasm's. These treatments can cause immunological disorders such as allergy, anaphylaxis, lack of response immunogenicity care fields specialist in allergy and clinical immunology.
authors.affiliation: Servicio de Inmunología Clínica y Alergia, Centro Médico Nacional 20 de Noviembre, Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado, Ciudad de México, México. genavargas@gmail.com.
authors.forename: María Eugenia
authors.initials: ME
authors.lastname: Vargas-Camaño
authors.forename: Ricardo Leopoldo
authors.initials: RL
authors.lastname: Guido-Bayardo
authors.forename: Nora Ernestina
authors.initials: NE
authors.lastname: Martínez-Aguilar
authors.forename: María Isabel
authors.initials: MI
authors.lastname: Castrejón-Vázquez
mesh_terms: D056704:Adaptive Immunity / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate / Q000276:immunology; D007153:Immunologic Deficiency Syndromes / Q000150:complications* / Q000276:immunology; D009369:Neoplasms / Q000276:immunology* / Q000628:therapy
keywords: cancer; immunocompetent; immunomodulatory treatments; secondary immunodeficiency