title: [A case of donovanosis acquired in France].
abstract: BACKGROUND
  Donovanosis (granuloma inguinale) is a bacterial infection caused by Klebsiella granulomatis that occurs mainly in the genital area and is primarily sexually transmitted; it is seen predominantly in the tropics. Herein, we report a case of the disease contracted in metropolitan France.
  
  
  METHODS
  A 47-year-old man presented with painless ulceration of the glans, present for one month, with progressive extension; there was no history of any recent trip abroad. Skin biopsy with Whartin-Starry and Giemsa staining revealed Donovan bodies in the cytoplasm of macrophages. Based on these findings, further questioning of the patient revealed unprotected sexual contact two months earlier in France. Treatment was initiated with azithromycin 1g on the first day followed by 500mg per day for three weeks. The clinical outcome was spectacular, with almost complete regression of the ulcer at 7 days.
  
  
  CONCLUSIONS
  This case demonstrates that donovanosis can occur in metropolitan France.
authors.affiliation: Service d'anatomie et cytologie pathologiques, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France; Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France. Electronic address: ilonaokh@hotmail.fr.
authors.forename: I
authors.initials: I
authors.lastname: Okhremchuk
authors.affiliation: Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.
authors.forename: E
authors.initials: E
authors.lastname: Marmottant
authors.affiliation: Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.
authors.forename: S
authors.initials: S
authors.lastname: Abed
authors.affiliation: Service d'anatomie et cytologie pathologiques, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.
authors.forename: A-T
authors.initials: AT
authors.lastname: Nguyen
authors.affiliation: Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.
authors.forename: B
authors.initials: B
authors.lastname: Fournier
authors.affiliation: Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.
authors.forename: T
authors.initials: T
authors.lastname: Boye
authors.affiliation: Service de dermatologie et de vénérologie, HIA Sainte-Anne, 2, boulevard Sainte-Anne, 83800 Toulon, France.
authors.forename: J-J
authors.initials: JJ
authors.lastname: Morand
mesh_terms: D003593:Cytoplasm / Q000382:microbiology; D005602:France; D006100:Granuloma Inguinale / Q000175:diagnosis*; D006801:Humans; D008264:Macrophages / Q000166:cytology / Q000382:microbiology; D008297:Male; D008875:Middle Aged; D010409:Penile Diseases / Q000382:microbiology*
keywords: Autochthonous infection; Donovanose; Donovanosis; France; Granuloma inguinale; Granulome inguinal; Infection autochtone