title: [Neonatal and child tetanus morbidity and mortality in the University hospitals of Abidjan, Côte d'Ivoire (2001-2010)].
abstract: The lack of data on neonatal tetanus and children in university hospitals (UH) in Abidjan for over a decade has motivated the realization of this study. The objective of this study is to evaluate the morbidity and mortality related to neonatal tetanus (NT) and child tetanus (CT) in Abidjan University Hospital from 2001 to 2010. It is a retrospective study, multicenter analysis with records of newborns and children suffering from tetanus in the three UH of Abidjan. The collection and analysis of data were made by the SPHINX 4.5 and EPI.INFO 6.0 software. In ten years, 242 cases of tetanus (53 NT cases and 189 CT cases) were collected with a predominance of cases after the fifth year of life (59.5%). The incidence rate of NT was less than 1 case per 1,000 live births. All mothers of the newborns were inhabiting the city of Abidjan. Their median age was 19 years [16-32] and 64% were teenagers. Gateways were dominated by umbilical wounds (77.3%) in the NTand skin wounds (59%) in CT. The cure rate was 30.2% in the NT and 60% in the CT. Lethality was 60% for NT and 22% for CT with a positive correlation with young age (neonates: p = 4.10-7, age <5 years: p = 0.01), lack of intraspinal injection of tetanus serum (p = 8.10-6), the absence of conventional antibiotic therapy (p = 0.023), the existence of metabolic complications (p = 2.10-5), the score of ≥ 4 Dakar (p = 0.005). Tetanus remains a real morbidly cause among children in Abidjan University Hospital with high lethality. However, the incidence of NT seems consistent with the incidence threshold desired by WHO.
authors.affiliation: Département de santé publique et Infectiologie, Université Alassane Ouattara de Bouaké, Côte d'Ivoire, France. chefaba@yahoo.fr.
authors.forename: Y T
authors.initials: YT
authors.lastname: Aba
authors.affiliation: Service de pédiatrie médicale, CHU de Treichville, Côte d'Ivoire, France.
authors.forename: L
authors.initials: L
authors.lastname: Cissé
authors.affiliation: Service de pédiatrie médicale, CHU de Treichville, Côte d'Ivoire, France.
authors.forename: A K
authors.initials: AK
authors.lastname: Abalé
authors.affiliation: Service de neurologie médicale, CHU de Yopougon, Côte d'Ivoire, France.
authors.forename: I
authors.initials: I
authors.lastname: Diakité
authors.affiliation: Département de santé publique et Infectiologie, Université Alassane Ouattara de Bouaké, Côte d'Ivoire, France.
authors.forename: D
authors.initials: D
authors.lastname: Koné
authors.affiliation: Département de santé publique et Infectiologie, Université Alassane Ouattara de Bouaké, Côte d'Ivoire, France.
authors.forename: J
authors.initials: J
authors.lastname: Kadiané
authors.affiliation: Service des maladies infectieuses et tropicales, CHU de Treichville, Côte d'Ivoire, France.
authors.forename: Z
authors.initials: Z
authors.lastname: Diallo
authors.affiliation: Département de santé publique et Infectiologie, Université Alassane Ouattara de Bouaké, Côte d'Ivoire, France.
authors.forename: O
authors.initials: O
authors.lastname: Kra
authors.affiliation: Service de pédiatrie médicale, CHU de Treichville, Côte d'Ivoire, France.
authors.forename: S
authors.initials: S
authors.lastname: Oulaï
authors.affiliation: Service des maladies infectieuses et tropicales, CHU de Treichville, Côte d'Ivoire, France.
authors.forename: E
authors.initials: E
authors.lastname: Bissagnéné
mesh_terms: D000293:Adolescent; D000328:Adult; D046688:Child Mortality; D002675:Child, Preschool; D007560:Cote d'Ivoire / Q000453:epidemiology; D005260:Female; D017052:Hospital Mortality; D006785:Hospitals, University / Q000706:statistics & numerical data; D006801:Humans; D007223:Infant; D007226:Infant Mortality; D007231:Infant, Newborn; D007232:Infant, Newborn, Diseases / Q000453:epidemiology* / Q000401:mortality; D008297:Male; D008423:Maternal Age; D009017:Morbidity; D012189:Retrospective Studies; D013742:Tetanus / Q000151:congenital / Q000453:epidemiology* / Q000401:mortality; D055815:Young Adult
keywords: Abidja; Child tetanus; Côte d’Ivoire; Incidence; Morbidity; Mortality; Neonatal tetanus; Sub-Saharan Africa; Teaching hospital