title: Rare complications after lung percutaneous radiofrequency ablation: Incidence, risk factors, prevention and management.
abstract: Among image-guided thermo-ablative techniques, percutaneous radiofrequency ablation (PRFA) is the most widely used technique for the treatment of primary and secondary lung malignancies. Tolerance of PRFA in the lung is excellent. However, relatively little is known about potential rare complications. This article presents both the clinical and imaging features of lung PRFA complications as well as their prevention and management. Complications may be classified in four groups: pleuropulmonary (e.g., bronchopleural or bronchial fistula, delayed abscess or aspergilloma inside post-PRFA cavitations, pulmonary artery pseudo aneurysm, gas embolism and interstitial pneumonia); thoracic wall and vertebral (e.g., rib or vertebral fractures and intercostal artery injury); mediastinal and apical (e.g., neural damage); or diaphragmatic. Most complications can be managed with conservative treatment, percutaneous or endoscopic drainage, or surgical repair.
authors.affiliation: Department of Interventional Radiology, Institut Bergonié, Comprehensive Cancer Centre, 229 cours de l'Argonne, 33076 Bordeaux, France. Electronic address: nicoalbertibdx@gmail.com.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Alberti
authors.affiliation: Department of Interventional Radiology, Institut Bergonié, Comprehensive Cancer Centre, 229 cours de l'Argonne, 33076 Bordeaux, France. Electronic address: xavier.buy@gmail.com.
authors.forename: Xavier
authors.initials: X
authors.lastname: Buy
authors.affiliation: Department of Radiology, Saint-Andre Hospital, 1 Rue Jean Burguet, 33000 Bordeaux, France. Electronic address: norafrulio@yahoo.fr.
authors.forename: Nora
authors.initials: N
authors.lastname: Frulio
authors.affiliation: Department of Radiology, Haut-Leveque Hospital, 1 Avenue Magellan, 33600 Pessac, France. Electronic address: michel.montaudon@chu-bordeaux.fr.
authors.forename: Michel
authors.initials: M
authors.lastname: Montaudon
authors.affiliation: Department of Interventional Radiology, Institut Bergonié, Comprehensive Cancer Centre, 229 cours de l'Argonne, 33076 Bordeaux, France. Electronic address: marionkgilles@gmail.com.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Canella
authors.affiliation: Department of Radiology, Civil Hospital, 1 Place de l'Hopital, 67000 Strasbourg, France. Electronic address: gangi@unistra.fr.
authors.forename: Afshin
authors.initials: A
authors.lastname: Gangi
authors.affiliation: Department of Interventional Radiology, Institut Bergonié, Comprehensive Cancer Centre, 229 cours de l'Argonne, 33076 Bordeaux, France. Electronic address: crombeamandine2@gmail.com.
authors.forename: Amandine
authors.initials: A
authors.lastname: Crombe
authors.affiliation: Department of Interventional Radiology, Institut Bergonié, Comprehensive Cancer Centre, 229 cours de l'Argonne, 33076 Bordeaux, France. Electronic address: J.Palussiere@bordeaux.unicancer.fr.
authors.forename: Jean
authors.initials: J
authors.lastname: Palussière
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D017115:Catheter Ablation / Q000009:adverse effects* / Q000379:methods; D005260:Female; D006801:Humans; D015994:Incidence; D008168:Lung / Q000000981:diagnostic imaging / Q000601:surgery; D008175:Lung Neoplasms / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000000981:diagnostic imaging / Q000453:epidemiology* / Q000517:prevention & control*; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
keywords: CT; Complications; Lung; Percutaneous radiofrequency ablation