title: Preoperative embolization of primary bone tumors: A case control study.
abstract: OBJECTIVE
  To study the safety and effectiveness of preoperative embolization of primary bone tumors in relation to intraoperative blood loss, intraoperative blood transfusion volume and surgical time.
  
  
  METHODS
  Thirty-three patients underwent preoperative embolization of primary tumors of extremities, hip or vertebrae before resection and stabilization. The primary osseous tumors included giant cell tumors, aneurysmal bone cyst, osteoblastoma, chondroblastoma and chondrosarcoma. Twenty-six patients were included for the statistical analysis (embolization group) as they were operated within 0-48 h within preoperative embolization. A control group (non-embolization group, n = 28) with bone tumor having similar histological diagnosis and operated without embolization was retrieved from hospital record for statistical comparison.
  
  
  RESULTS
  The mean intraoperative blood loss was 1300 mL (250-2900 mL), the mean intraoperative blood transfusion was 700 mL (0-1400 mL) and the mean surgical time was 221 ± 76.7 min for embolization group (group I, n = 26). Non-embolization group (group II, n = 28), the mean intraoperative blood loss was 1800 mL (800-6000 mL), the mean intraoperative blood transfusion was 1400 mL (700-8400 mL) and the mean surgical time was 250 ± 69.7 min. On comparison, statistically significant (P < 0.001) difference was found between embolisation group and non-embolisation group for the amount of blood loss and requirement of blood transfusion. There was no statistical difference between the two groups for the surgical time. No patients developed any angiography or embolization related complications.
  
  
  CONCLUSIONS
  Preoperative embolization of bone tumors is a safe and effective adjunct to the surgical management of primary bone tumors that leads to reduction in intraoperative blood loss and blood transfusion volume.
authors.affiliation: Roushan Jha, Raju Sharma, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical sciences, New Delhi 110029, India.
authors.forename: Roushan
authors.initials: R
authors.lastname: Jha
authors.affiliation: Roushan Jha, Raju Sharma, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical sciences, New Delhi 110029, India.
authors.forename: Raju
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Roushan Jha, Raju Sharma, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical sciences, New Delhi 110029, India.
authors.forename: Shishir
authors.initials: S
authors.lastname: Rastogi
authors.affiliation: Roushan Jha, Raju Sharma, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical sciences, New Delhi 110029, India.
authors.forename: Shah Alam
authors.initials: SA
authors.lastname: Khan
authors.affiliation: Roushan Jha, Raju Sharma, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical sciences, New Delhi 110029, India.
authors.forename: Arvind
authors.initials: A
authors.lastname: Jayaswal
authors.affiliation: Roushan Jha, Raju Sharma, Shivanand Gamanagatti, Department of Radiodiagnosis, All India Institute of Medical sciences, New Delhi 110029, India.
authors.forename: Shivanand
authors.initials: S
authors.lastname: Gamanagatti
keywords: Bloodloss; Bone tumor; Embolisation; Preoperative; Surgery