title: An antimicrobial stewardship program reduces antimicrobial therapy duration and hospital stay in surgical wards.
abstract: We report a quasi-experimental study of the implementation of an antimicrobial stewardship program in two surgical wards, with a pre-intervention period with just assessment of prescription and an intervention period with a prospective audit on antibiotic prescription model. There was a significant reduction of length of stay and the total days of antimicrobial administration. There were no differences in mortality between groups. The antimicrobial stewardship program led to the early detection of inappropriate empirical antibiotic treatment and was associated with a significant reduction in length of stay and the total duration of antimicrobial therapy.
authors.affiliation: Robert Güerri Fernández, Infectious Diseases Dpt, Hospital del Mar, Paseo Marítimo 25-29, Barcelona 08003. Spain. rguerri@imim.es.
authors.forename: R
authors.initials: R
authors.lastname: Güerri-Fernández
authors.forename: J
authors.initials: J
authors.lastname: Villar-García
authors.forename: S
authors.initials: S
authors.lastname: Herrera-Fernández
authors.forename: M
authors.initials: M
authors.lastname: Trenchs-Rodríguez
authors.forename: J
authors.initials: J
authors.lastname: Fernández-Morato
authors.forename: L
authors.initials: L
authors.lastname: Moro
authors.forename: J
authors.initials: J
authors.lastname: Sancho
authors.forename: L
authors.initials: L
authors.lastname: Grande
authors.forename: A
authors.initials: A
authors.lastname: Clará
authors.forename: S
authors.initials: S
authors.lastname: Grau
authors.forename: J P
authors.initials: JP
authors.lastname: Horcajada
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000401:mortality; D003428:Cross Infection / Q000188:drug therapy / Q000401:mortality; D005260:Female; D017408:Guidelines as Topic; D017052:Hospital Mortality; D006801:Humans; D057970:Inappropriate Prescribing; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000188:drug therapy / Q000382:microbiology; D011446:Prospective Studies; D013503:Surgery Department, Hospital / Q000706:statistics & numerical data*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents