title: Lung Cancer Resets the Liver's Metabolic Clock.
abstract: The impact of a tumor on distant organs is not well characterized but may be important for understanding immune interactions and the process of metastasis. Masri and colleagues (2016) now identify an interesting effect of lung tumor development on circadian regulation of liver metabolism.
authors.affiliation: The Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON M5G 2C1, Canada; The Princess Margaret Cancer Centre and Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2C1, Canada.
authors.forename: Rob A
authors.initials: RA
authors.lastname: Cairns
authors.affiliation: The Campbell Family Institute for Breast Cancer Research, University Health Network, Toronto, ON M5G 2C1, Canada; The Princess Margaret Cancer Centre and Ontario Cancer Institute, University Health Network, Toronto, ON M5G 2C1, Canada. Electronic address: tmak@uhnresearch.ca.
authors.forename: Tak W
authors.initials: TW
authors.lastname: Mak
mesh_terms: D000230:Adenocarcinoma / Q000378:metabolism / Q000473:pathology; D000077192:Adenocarcinoma of Lung; D000818:Animals; D057906:Circadian Clocks; D006801:Humans; D008099:Liver / Q000378:metabolism*; D008175:Lung Neoplasms / Q000378:metabolism* / Q000473:pathology; D008954:Models, Biological; D009154:Mutation / Q000235:genetics; D015398:Signal Transduction