title: Genome-Wide Association Mapping of Barley Yellow Dwarf Virus Tolerance in Spring Oat (Avena sativa L.).
abstract: Barley yellow dwarf viruses (BYDVs) are responsible for the disease barley yellow dwarf (BYD) and affect many cereals including oat (Avena sativa L.). Until recently, the molecular marker technology in oat has not allowed for many marker-trait association studies to determine the genetic mechanisms for tolerance. A genome-wide association study (GWAS) was performed on 428 spring oat lines using a recently developed high-density oat single nucleotide polymorphism (SNP) array as well as a SNP-based consensus map. Marker-trait associations were performed using a Q-K mixed model approach to control for population structure and relatedness. Six significant SNP-trait associations representing two QTL were found on chromosomes 3C (Mrg17) and 18D (Mrg04). This is the first report of BYDV tolerance QTL on chromosome 3C (Mrg17) and 18D (Mrg04). Haplotypes using the two QTL were evaluated and distinct classes for tolerance were identified based on the number of favorable alleles. A large number of lines carrying both favorable alleles were observed in the panel.
authors.affiliation: Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
authors.forename: Bradley J
authors.initials: BJ
authors.lastname: Foresman
authors.affiliation: Department of Plant Sciences, North Dakota State University, Fargo, North Dakota, United States of America.
authors.forename: Rebekah E
authors.initials: RE
authors.lastname: Oliver
authors.affiliation: General Mills Crop Bioscience, Manhattan, Kansas, United States of America.
authors.forename: Eric W
authors.initials: EW
authors.lastname: Jackson
authors.affiliation: USDA-ARS Cereal Crops Research Unit, Fargo, North Dakota, United States of America.
authors.forename: Shiaoman
authors.initials: S
authors.lastname: Chao
authors.affiliation: Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
authors.forename: Marcio P
authors.initials: MP
authors.lastname: Arruda
authors.affiliation: Department of Crop Sciences, University of Illinois at Urbana-Champaign, Urbana, Illinois, United States of America.
authors.forename: Frederic L
authors.initials: FL
authors.lastname: Kolb
mesh_terms: D000483:Alleles; D018554:Avena / Q000235:genetics* / Q000821:virology*; D002874:Chromosome Mapping; D060467:Disease Resistance / Q000235:genetics*; D005828:Genetics, Population; D018745:Genome, Plant; D055106:Genome-Wide Association Study; D005838:Genotype; D006239:Haplotypes; D017793:Luteovirus / Q000502:physiology*; D010641:Phenotype; D010935:Plant Diseases / Q000235:genetics* / Q000821:virology*; D020641:Polymorphism, Single Nucleotide; D040641:Quantitative Trait Loci; D019655:Quantitative Trait, Heritable