title: Bioaccumulation of perfluoroalkyl acids including the isomers of perfluorooctane sulfonate in carp (Cyprinus carpio) in a sediment/water microcosm.
abstract: Carp (Cyprinus carpio) were exposed to perfluoroalkyl acids (PFAAs) including perfluorooctane sulfonate (PFOS) isomers in an artificially contaminated sediment/water microcosm. The uptake constant of PFAAs increased with increasing carbon chain length, whereas the elimination coefficient displayed the opposite trend, suggesting that carbon chain length plays an important role in the bioaccumulation of PFAAs. When the contribution of suspended particulate matter was taken into account, the bioaccumulation factors (BAFs) became lower (3.61-600 L/kg) compared with BAFs derived from only considering the absorption from free PFAAs in water (3.85-97000 L/kg). The results indicate that suspended particulate matter in water constitutes an important source of exposure for aquatic organisms to long-chain PFAAs. Linear (n-)PFOS was preferentially accumulated compared with branched isomers in carp. Among the branched isomers, 1m-PFOS displayed the greatest bioaccumulation, whereas m2-PFOS had the lowest. Linear PFOS displayed greater partitioning ability from blood to other tissues over branched PFOS (br-PFOS) isomers, leading to a relatively lower n-PFOS proportion in blood. In summary, suspended particulate matter made a contribution to the accumulation of long-chain PFAAs in aquatic organisms, and n-PFOS was preferentially accumulated compared with br-PFOS isomers. Environ Toxicol Chem 2016;35:3005-3013. © 2016 SETAC.
authors.affiliation: Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin, People's Republic of China.|College of Resources and Environment, Chengdu University of Information Technology, Chengdu, People's Republic of China.
authors.forename: Shuhong
authors.initials: S
authors.lastname: Fang
authors.affiliation: Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin, People's Republic of China.
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin, People's Republic of China.
authors.forename: Shuyan
authors.initials: S
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin, People's Republic of China.
authors.forename: Liwen
authors.initials: L
authors.lastname: Qiang
authors.affiliation: Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin, People's Republic of China.
authors.forename: Meng
authors.initials: M
authors.lastname: Chen
authors.affiliation: Key Laboratory of Pollution Processes and Environmental Criteria, Ministry of Education, Tianjin Key Laboratory of Environmental Remediation and Pollution Control, College of Environmental Science and Engineering, Nankai University, Tianjin, People's Republic of China.|College of Natural Resources and Environment, Northwest A&F University, Yang Ling, People's Republic of China.
authors.forename: Lingyan
authors.initials: L
authors.lastname: Zhu
mesh_terms: D017738:Alkanesulfonic Acids / Q000737:chemistry / Q000378:metabolism*; D000818:Animals; D002347:Carps / Q000254:growth & development / Q000378:metabolism*; D005466:Fluorocarbons / Q000737:chemistry / Q000378:metabolism*; D019015:Geologic Sediments / Q000737:chemistry; D007536:Isomerism; D052638:Particulate Matter / Q000737:chemistry; D014018:Tissue Distribution; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000378:metabolism*
chemical_list: D017738:Alkanesulfonic Acids; D005466:Fluorocarbons; D052638:Particulate Matter; D014874:Water Pollutants, Chemical; C076994:perfluorooctane sulfonic acid
keywords: Bioaccumulation; Fish; Isomers; perfluoroalkyl acids (PFAAs)