title: The Bugs Within Our Body: The Human Microbiota.
abstract: The human microbiota is the ecological community of microorganisms that live within our bodies. Emerging evidence has revealed that dysregulation of the host-microbe symbiotic relationship contributes to the pathogenesis of a vast number of human diseases and impacts the efficacy and toxicity of therapeutic drugs. Therefore, a deeper understanding of the human microbiota is crucial to the development of therapeutic interventions that target the microbiota and also provides fundamental insights towards understanding intersubject variability in therapeutic outcomes.
authors.affiliation: Department of Immunology, University of Toronto, Toronto, ON, Canada.
authors.forename: D J
authors.initials: DJ
authors.lastname: Philpott
authors.affiliation: Leslie Dan Faculty of Pharmacy, University of Toronto, Toronto, ON, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Piquette-Miller
mesh_terms: D004032:Diet; D006801:Humans; D064307:Microbiota / Q000187:drug effects; D010601:Pharmacology, Clinical / Q000379:methods / Q000639:trends