title: Clinical Inquiry: Does caffeine intake during pregnancy affect birth weight?
abstract: No. Reducing caffeinated coffee consumption by 180 mg of caffeine (the equivalent of 2 cups) per day after 16 weeks' gestation doesn't affect birth weight. Consuming more than 300 mg of caffeine per day is associated with a clinically trivial, and statistically insignificant (less than 1 ounce), reduction in birth weight, compared with consuming no caffeine.
authors.affiliation: University of Washington Family Medicine Residency at Valley Medical Center, Renton, WA, USA.
authors.forename: Taralee
authors.initials: T
authors.lastname: Adams
authors.affiliation: University of Washington Family Medicine Residency at Valley Medical Center, Renton, WA, USA.
authors.forename: Gary
authors.initials: G
authors.lastname: Kelsberg
authors.affiliation: University of Washington Health Sciences Library, Seattle, WA, USA.
authors.forename: Sarah
authors.initials: S
authors.lastname: Safranek
mesh_terms: D000328:Adult; D001724:Birth Weight / Q000187:drug effects*; D002110:Caffeine / Q000009:adverse effects*; D003069:Coffee / Q000009:adverse effects*; D015331:Cohort Studies; D004305:Dose-Response Relationship, Drug; D005260:Female; D005865:Gestational Age; D006801:Humans; D008875:Middle Aged; D011247:Pregnancy; D011248:Pregnancy Complications / Q000209:etiology*; D011446:Prospective Studies; D018570:Risk Assessment; D055815:Young Adult
chemical_list: D003069:Coffee; D002110:Caffeine