title: [Region-wide professional practice evaluation with regards to antiemetic prescription into chemotherapy-induced nausea and vomiting].
abstract: The anticancer drug technical commission (COTECH) of the Auvergne OMEDIT has set up a region-wide professional practice evaluation (PPE) with regards to antiemetic prescription practices in chemotherapy-induced nausea and vomiting (CINV), in order to evaluate their compliance with OMEDIT's guidelines. Are not included pediatric and hematologic protocols. A prospective survey was carried from November 2013 to January 2014 out in 14 medical centers in Auvergne. This clinical audit was based on the HAS (national healthcare authority) framework and used as a reference regional standards based on the MASCC Antiemetic Guidelines. Altogether, 346 antiemetic prescriptions were compared to guidelines. We observed respectively 81 % and 42 % conformity rates in acute and delayed emesis for high emesis risk chemotherapy (HE); 86 % and 35 % conformity rates in acute and delayed emesis for moderate emesis risk chemotherapy (ME); 66 % and 85 % conformity rates in acute and delayed emesis for low emesis risk chemotherapy (LE). These results highlight deficiencies in compliance with guidelines, especially in the management of delayed CINV in HE and ME chemotherapy. The COTECH identified three priority improvement areas: under-prescribe NK1 antagonists in HE cure; under-prescribe corticosteroid; over-prescribe 5HT3 antagonists for delayed emesis. The COTECH is publicizing these results all over the Auvergne region, together with a reminder of recommendations.
authors.affiliation: Centre hospitalier de Vichy, boulevard Denière, 03200 Vichy, France. Electronic address: tavernier.jerome@hotmail.fr.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Tavernier
authors.affiliation: CHU de Clermont-Ferrand, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: Mireille
authors.initials: M
authors.lastname: Jouannet-Romaszko
authors.affiliation: Centre hospitalier de Vichy, boulevard Denière, 03200 Vichy, France.
authors.forename: Helena
authors.initials: H
authors.lastname: Bertucat
authors.affiliation: Centre hospitalier d'Ambert, avenue G.-Clemenceau, 63600 Ambert, France.
authors.forename: Nathalie
authors.initials: N
authors.lastname: Marchiset
authors.affiliation: Centre Jean-Perrin, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: Mohum
authors.initials: M
authors.lastname: Bahadoor
authors.affiliation: Centre Jean-Perrin, rue Montalembert, 63000 Clermont-Ferrand, France.
authors.forename: Régine
authors.initials: R
authors.lastname: Chevrier
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000932:Antiemetics / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000145:classification; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D019983:Guideline Adherence; D006801:Humans; D009325:Nausea / Q000139:chemically induced / Q000188:drug therapy*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011364:Professional Practice; D011795:Surveys and Questionnaires; D014839:Vomiting / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D000305:Adrenal Cortex Hormones; D000932:Antiemetics; D000970:Antineoplastic Agents
keywords: Antiemetic; Antiémétique; Audit; Chemotherapy; Chimiothérapie; Nausea; Nausées; Prescription; Vomissements; Vomiting