title: MULTICOLOR IMAGING OF INNER RETINAL ALTERATIONS AFTER INTERNAL LIMITING MEMBRANE PEELING.
abstract: OBJECTIVE
  To characterize the appearance of inner retinal alterations after internal limiting membrane (ILM) peeling using multicolor confocal scanning laser ophthalmoscopy (cSLO).
  
  
  METHODS
  Retrospective review of two eyes that underwent pars plana vitrectomy with internal limiting membrane peeling and postoperative multicolor cSLO with spectral-domain optical coherence tomography. Infrared, green, blue, standard multicolor, and blue-green enhanced multicolor reflectance images were evaluated alongside spectral-domain optical coherence tomography for inner retinal alterations.
  
  
  RESULTS
  Two eyes of 2 patients, aged 70 and 65 years, were identified. Preoperative diagnoses were epiretinal membrane with lamellar macular hole for Case 1 and full-thickness macular hole for Case 2. Time from surgery to initial multicolor cSLO imaging was 9 years in Case 1 and 3 weeks in Case 2. Inner retinal alterations were best visualized on blue reflectance, moderately visualized on green and blue-green enhanced multicolor, and less evident on infrared and standard multicolor. In Case 2, serial multicolor cSLO imaging demonstrated the emergence of inner retinal alterations between 3 weeks and 5 weeks postoperatively.
  
  
  CONCLUSIONS
  Multicolor cSLO is a novel imaging modality capable of detecting inner retinal alterations in patients with a history of internal limiting membrane peeling, and may be clinically useful for monitoring anatomical changes associated with internal limiting membrane peeling.
authors.affiliation: *Rutgers Robert Wood Johnson Medical School, Piscataway, New Jersey; and †Duke Eye Center, Duke University, Durham, North Carolina.
authors.forename: Henry L
authors.initials: HL
authors.lastname: Feng
authors.forename: Sumit
authors.initials: S
authors.lastname: Sharma
authors.forename: Sanjay
authors.initials: S
authors.lastname: Asrani
authors.forename: Prithvi
authors.initials: P
authors.lastname: Mruthyunjaya
mesh_terms: D000368:Aged; D016570:Bruch Membrane / Q000000981:diagnostic imaging / Q000601:surgery*; D003952:Diagnostic Imaging / Q000379:methods*; D019773:Epiretinal Membrane / Q000175:diagnosis / Q000601:surgery*; D005451:Fluorescein Angiography / Q000379:methods; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D009887:Ophthalmoscopy / Q000379:methods*; D012160:Retina / Q000473:pathology*; D012167:Retinal Perforations / Q000175:diagnosis / Q000601:surgery*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*