title: Baiting for Cancer: Using the Zebrafish as a Model in Liver and Pancreatic Cancer.
abstract: Liver and pancreatic cancers are amongst the leading causes of cancer death. In recent years, genetic and chemical approaches in zebrafish have elucidated cellular and molecular mechanisms of liver and pancreatic cancer formation and progression. In this chapter, we review the recent approaches and advances in the field to study both hepatocellular carcinomas and pancreatic cancer.
authors.affiliation: Harvard Medical School, Medical Scientist Training Program, Boston, MA, USA.|Genetics Division, Brigham and Women's Hospital, Boston, MA, USA.
authors.forename: Katie L
authors.initials: KL
authors.lastname: Hwang
authors.affiliation: Genetics Division, Brigham and Women's Hospital, Boston, MA, USA. wolfram_goessling@dfci.harvard.edu.|Gastrointestinal Cancer Center, Dana-Farber Cancer Institute, Boston, MA, USA. wolfram_goessling@dfci.harvard.edu.|Broad Institute of MIT and Harvard, Cambridge, MA, USA. wolfram_goessling@dfci.harvard.edu.|Harvard Stem Cell Institute, Cambridge, MA, Cambridge, MA, USA. wolfram_goessling@dfci.harvard.edu.
authors.forename: Wolfram
authors.initials: W
authors.lastname: Goessling
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D008113:Liver Neoplasms / Q000139:chemically induced / Q000235:genetics / Q000473:pathology*; D010190:Pancreatic Neoplasms / Q000235:genetics / Q000473:pathology*; D015027:Zebrafish
keywords: Liver cancer; Liver development; Mutations; Pancreas cancer; Pancreas development; Transgenesis; Zebrafish