title: Captopril-induced sialadenitis in a patient with end-stage renal disease.
abstract: Sialadenitis is a rare adverse effect of captopril. We report a case of captopril-induced sialadenitis in a patient with end-stage renal disease (ESRD). A 20-year-old man with ESRD encountered parotid and submandibular swelling after receiving two doses of captopril, administered sublingually. Despite of prescribing dexamethasone, resuming hemodialysis, and discontinuing other drugs that also can cause parotitis, he improved later than what was reported in patients with normal renal function. In conclusion recovery from captopril-induced sialadenitis in patients with ESRD may be more prolonged than that of patients with normal renal function; moreover, early hemodialysis which helps in drug removal may be the most effective treatment.
authors.affiliation: Department of Internal Medicine, Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Fatemeh Musavi
authors.initials: FM
authors.lastname: Mahdiabadi
authors.affiliation: Pharmaceutics Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
authors.forename: Naemeh
authors.initials: N
authors.lastname: Nikvarz
keywords: Captopril; end-stage renal disease; sialadenitis