title: Monitoring 3D dose distributions in proton therapy by reconstruction using an iterative method.
abstract: The Bragg peak of protons can be determined by measuring prompt γ-rays. In this study, prompt γ-rays detected by single-photon emission computed tomography with a geometrically optimized collimation system were reconstructed by an iterative method. The falloff position by iterative method (52.48mm) was most similar to the Bragg peak (52mm) of an 80MeV proton compared with those of back-projection (54.11mm) and filtered back-projection (54.91mm) methods. Iterative method also showed better image performance than other methods.
authors.affiliation: Department of Bio-Convergence Engineering, Korea University, Hana Science Hall 277, Korea Univ. Anam Campus, Anam-dong 5-ga, Seongbuk-gu, Seoul, Korea.
authors.forename: Young-Hak
authors.initials: YH
authors.lastname: Kim
authors.affiliation: Department of Bio-Convergence Engineering, Korea University, Hana Science Hall 277, Korea Univ. Anam Campus, Anam-dong 5-ga, Seongbuk-gu, Seoul, Korea.
authors.forename: Changyeon
authors.initials: C
authors.lastname: Yoon
authors.affiliation: School of Health and Environmental Science, Korea University, Hana Science Hall 278, Korea Univ. Anam Campus, Anam-dong 5-ga, Seongbuk-gu, Seoul, Korea. Electronic address: wonhol@korea.ac.kr.
authors.forename: Wonho
authors.initials: W
authors.lastname: Lee
mesh_terms: D003198:Computer Simulation; D005720:Gamma Rays; D006801:Humans; D007091:Image Processing, Computer-Assisted; D021621:Imaging, Three-Dimensional; D009369:Neoplasms / Q000532:radiotherapy; D019047:Phantoms, Imaging; D061766:Proton Therapy; D011522:Protons; D011834:Radiation Monitoring / Q000706:statistics & numerical data; D011879:Radiotherapy Dosage; D020266:Radiotherapy, Conformal; D013051:Spectrometry, Gamma / Q000706:statistics & numerical data; D015899:Tomography, Emission-Computed, Single-Photon
chemical_list: D011522:Protons
keywords: Bragg peak; Iterative reconstruction method; Prompt γ-Rays; Proton therapy; Single-Photon Emission Computed Tomography (SPECT)