title: Periodontally diseased tooth roots used for lateral alveolar ridge augmentation. A proof-of-concept study.
abstract: To assess the efficacy of periodontally diseased tooth roots used as autografts for lateral ridge augmentation and two-stage early osseointegration of titanium implants.
  
  
  
  Ligature-induced periodontitis lesions were established at the maxillary premolars in n = 8 foxhounds. Extracted, scaled and root planed pre-molar roots (PM-P) as well as retromolar cortical autogenous bone (AB) blocks were used for horizontal ridge augmentation of mandibular chronic-type defects. At 12 weeks, titanium implants were inserted and left to heal for another 3 weeks. Histological analyses included crestal ridge width (CW), augmented area (AA) and bone-to-implant contact (BIC).
  
  
  
  Both PM-P and AB grafts were gradually organized and replaced by newly formed bone. Median CW (PM-P: 3.83 versus AB: 3.67 mm), AA (PM-P: 10.18 versus AB: 9.82 mm(2) ) and BIC (PM-P: 50.00% versus AB: 35.21%) values did not reach statistical significance between groups (p > 0.05, respectively). Histologically, PM-P grafts were not associated with any inflammatory cell infiltrates.
  
  
  
  PM-P autografts may reveal a structural and biological potential to serve as an alternative autograft to AB.
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Frank
authors.initials: F
authors.lastname: Schwarz
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Golubovic
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Ilja
authors.initials: I
authors.lastname: Mihatovic
authors.affiliation: Department of Oral Surgery, Universitätsklinikum Düsseldorf, Düsseldorf, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Becker
mesh_terms: D000540:Alveolar Ridge Augmentation; D016025:Bone Transplantation; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D006801:Humans; D016348:Osseointegration; D014092:Tooth Root
chemical_list: D015921:Dental Implants
keywords: alveolar ridge augmentation; extraction; histological technique; periodontal disease; tooth transplantation