title: Investigation of Nonneoplastic Neurologic Disorders with PET and MRI.
abstract: Neuroimaging with positron emission tomography (PET) provides metabolic and molecular information that cannot be obtained from other imaging modalities and provides novel insights into the pathogenesis and diagnosis of a diverse array of neurologic diseases. As the library of novel PET ligands expands, so does the potential role for PET in the study of neurologic disease. The emergence of PET amyloid imaging reveals the incredible potential for PET neuroimaging. Recent technical advances in our ability to combine structural MR imaging data with functional and molecular PET data have enhanced the power of PET for the study of the brain. Thus, PET and MR imaging should continue to play an expanding role in the diagnosis and investigation of neurologic disease conditions.
authors.affiliation: Department of Neurology, University of Pennsylvania Medical Center, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA.
authors.forename: Erik S
authors.initials: ES
authors.lastname: Musiek
authors.affiliation: Division of Thoracic Imaging, Department of Radiology, University of Pennsylvania Medical Center, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA; Division of Body Computed Tomography, Department of Radiology, University of Pennsylvania Medical Center, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA; Division of Body MR Imaging, Department of Radiology, University of Pennsylvania Medical Center, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA.
authors.forename: Drew A
authors.initials: DA
authors.lastname: Torigian
authors.affiliation: Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania Medical Center, 110 Donner Building, 3400 Spruce Street, Philadelphia, PA 19104, USA. Electronic address: andrew.newberg@uphs.upenn.edu.
authors.forename: Andrew B
authors.initials: AB
authors.lastname: Newberg
keywords: Alzheimer; Brain; Dementia; MR imaging; Neurodegenerative; Neurologic; PET/MR imaging; Positron emission tomography