title: Trabeculectomy Versus Ex-Press Glaucoma Filtration Device in Silicomacrophagocytic Open Angle Glaucoma Secondary to Silicone Oil Emulsification.
abstract: OBJECTIVE
  To compare the outcomes of Ex-PRESS device implantation versus trabeculectomy in patients with ocular hypertension after pars plana vitrectomy and silicone oil injection (SOI).
  
  
  METHODS
  Twenty-six consecutive eyes with ocular hypertension after pars plana vitrectomy and SOI were included in this study and randomized to one of two groups: A group treated with Ex-PRESS (model P50) placed under a scleral flap (Ex-PRESS group), and a group treated with trabeculectomy (trabeculectomy group). Complete success (intraocular pressure [IOP] <21 mmHg without medication) and qualified success rates (IOP <21 mmHg with one or two glaucoma medications) at 2 years postoperatively were analyzed. Between-groups comparison was performed with the Mann-Whitney U-test for continuous variables, and Fischer exact test for categorical data. Success rates between groups were compared using Kaplan-Meier life analysis and the log-rank test. P < 0.05 was considered statistically significant.
  
  
  RESULTS
  In the Ex-PRESS group, complete success was achieved in 73% eyes and qualified success in 81.8% of eyes. In the trabeculectomy group, complete success was achieved in 40% and qualified success was achieved in 60% of eyes. The difference in mean IOP between groups was statistically significant from the 3(rd) postoperative month onward (P = 0.007 at 3 months, P = 0.003 at 6 months, and P = 0.03 at 24 months).
  
  
  CONCLUSIONS
  Ex-PRESS implantation was more effective than trabeculectomy in controlling IOP in ocular hypertensives after pars plana vitrectomy and SOI, but the surgical technique may require improvement.
authors.affiliation: Ophthalmology Unit, Azienda Ospedaliera "Cardinale G. Panico", Lecce, Italy.
authors.forename: Donato
authors.initials: D
authors.lastname: Errico
authors.affiliation: Ophthalmology Unit, Azienda Ospedaliera "Cardinale G. Panico", Lecce, Italy.
authors.forename: Francesca Luigia
authors.initials: FL
authors.lastname: Scrimieri
authors.affiliation: Ophthalmology Unit, Azienda Ospedaliera "Cardinale G. Panico", Lecce, Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Riccardi
authors.affiliation: Department of Ophthalmology, Ospedale Pediatrico Bambino Gesù, Rome, Italy.
authors.forename: Giancarlo
authors.initials: G
authors.lastname: Iarossi
mesh_terms: D000328:Adult; D000368:Aged; D004655:Emulsions; D058450:Endotamponade / Q000009:adverse effects*; D005260:Female; D020327:Glaucoma Drainage Implants; D005902:Glaucoma, Open-Angle / Q000209:etiology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D012827:Silicone Oils; D014065:Tonometry, Ocular; D014130:Trabeculectomy / Q000379:methods*; D014821:Vitrectomy; D057586:Vitreoretinal Surgery
chemical_list: D004655:Emulsions; D012827:Silicone Oils
keywords: Ex-PRESS; Mitomycin C; Silicomacrophagocytic Open Angle Glaucoma; Trabeculectomy