title: Multimodal oncosurgery approach to treat peritoneal carcinomatosis in a patient with occlusive ovarian carcinoma.
abstract: Summary
  
  
  BACKGROUND
  This paper aims to present a "pattern" of oncosurgery solution in a case generally considered unrecoverable: intestinal occlusion in case of ovarian carcinoma and carcinomatosis.
  
  
  METHODS
  A 62-year-old female patient with ascites, carcinomatosis, unresectable pelvic tumour, and intestinal obstruction suffered a five-step oncosurgery "model": three surgical interventions overlapping chemotherapy administered via the systemic and intraperitoneal route: Step 1: colostomy and partial omentectomy; Step 2: five courses of systemic chemotherapy supported by granulocyte colony-stimulating factor; Step 3: radical surgery--total hysterectomy, bilateral adnexectomy, pelvic lymphadenectomy, omentectomy, appendectomy, pelvic peritonectomy, and hyperthermic intraperitoneal chemotherapy; Step 4: consolidation systemic chemotherapy consisting of three more similar cycles; Step 5: closure of the colostomy. Nine months after the beginning of treatment, the patient is with no evidence of disease.
  
  
  CONCLUSIONS
  The association of surgical and oncologic treatment and the use of hyperthermic intraperitoneal chemotherapy (HIPEC) technology can solve some of these complex cases.
authors.forename: B
authors.initials: B
authors.lastname: Moldovan
authors.forename: F
authors.initials: F
authors.lastname: Pescaru
authors.forename: D
authors.initials: D
authors.lastname: Pocreaţă
authors.forename: P
authors.initials: P
authors.lastname: Biriş
authors.forename: A
authors.initials: A
authors.lastname: Moldovan
authors.forename: M E
authors.initials: ME
authors.lastname: Căpîlna
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D002277:Carcinoma / Q000150:complications / Q000473:pathology / Q000628:therapy*; D003125:Colostomy; D060830:Consolidation Chemotherapy; D065426:Cytoreduction Surgical Procedures; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D007044:Hysterectomy; D007263:Infusions, Parenteral; D007415:Intestinal Obstruction / Q000209:etiology / Q000601:surgery*; D008197:Lymph Node Excision; D008875:Middle Aged; D009852:Omentum / Q000601:surgery*; D010051:Ovarian Neoplasms / Q000150:complications / Q000473:pathology / Q000628:therapy*; D010052:Ovariectomy; D010534:Peritoneal Neoplasms / Q000556:secondary / Q000628:therapy*; D010537:Peritoneum / Q000601:surgery*; D058994:Salpingectomy
chemical_list: D000970:Antineoplastic Agents