title: Giant cell tumor of the rib with direct invasion into the thoracic spine.
abstract: Giant cell tumors of bone are relatively rare, benign, but locally aggressive osteolytic skeletal neoplasms of young adults. They usually affect the epiphyses of long bones, especially around the knee joint, and are rarely seen in the ribs. The mainstay of therapy is surgical resection. Herein, we report a case of successful resection in a patient who presented with primary giant cell tumor of the rib, directly invading the thoracic spine. Computed tomography and magnetic resonance imaging were helpful for assessing the depth of tumor invasion. Radical resection of the tumor and reconstruction of the vertebrae with preserved allograft bone were performed. No respiratory or neurological problems occurred, and the patient remained well 2 years after surgery.
authors.affiliation: Department of Thoracic Surgery, Kobe City Medical Center General Hospital, 2-1-1 Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan. ichiro.sakanoue@gmail.com.
authors.forename: Ichiro
authors.initials: I
authors.lastname: Sakanoue
authors.affiliation: Department of Thoracic Surgery, Kobe City Medical Center General Hospital, 2-1-1 Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Hamakawa
authors.affiliation: Department of Orthopedics, Kobe City Medical Center General Hospital, Kobe, Japan.
authors.forename: Eijiro
authors.initials: E
authors.lastname: Onishi
authors.affiliation: Department of Pathology, Kobe City Medical Center General Hospital, Kobe, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Imai
authors.affiliation: Department of Thoracic Surgery, Kobe City Medical Center General Hospital, 2-1-1 Minatojimaminami-machi, Chuo-ku, Kobe, Hyogo, 650-0047, Japan.
authors.forename: Yutaka
authors.initials: Y
authors.lastname: Takahashi
mesh_terms: D000328:Adult; D001859:Bone Neoplasms / Q000473:pathology* / Q000601:surgery; D018212:Giant Cell Tumor of Bone / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007796:Laminectomy / Q000379:methods; D008279:Magnetic Resonance Imaging; D008297:Male; D009361:Neoplasm Invasiveness; D012272:Ribs / Q000000981:diagnostic imaging* / Q000601:surgery; D013125:Spinal Neoplasms / Q000473:pathology* / Q000601:surgery; D019616:Thoracic Surgical Procedures / Q000379:methods; D013904:Thoracic Vertebrae; D014057:Tomography, X-Ray Computed
keywords: Chest wall; Giant cell tumor; Reconstruction