title: How much of the human protein interactome remains to be mapped?
abstract: Using systematic approaches, a high-quality reference map of the human protein-protein interactome is within reach. Such a reference will help researchers connect genomic data to cellular phenotypes and enable full exploitation of the output of the genomic revolution for biomedical applications.
authors.affiliation: Marc Vidal, Center for Cancer Systems Biology (CCSB) and Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA, and Department of Genetics, Harvard Medical School, Boston, MA 02215, USA.
authors.forename: Marc
authors.initials: M
authors.lastname: Vidal
mesh_terms: D000818:Animals; D056726:Genetic Association Studies; D006801:Humans; D011485:Protein Binding; D025941:Protein Interaction Mapping; D020033:Protein Isoforms; D020543:Proteome; D012326:RNA Splicing; D015398:Signal Transduction
chemical_list: D020033:Protein Isoforms; D020543:Proteome