title: Treatment Challenges with Benign Bone Tumors of the Orbit.
abstract: Benign mesenchymal tumors of the craniofacial complex present unique challenges for orbital surgeons because of their potential for orbital compartment syndrome, ocular morbidity, and facial disfigurement and because definitive surgical management may be associated with significant morbidity. While the precise classification of such lesions depends on radiologic as well as histologic evaluations and remains controversial, benign tumors involving the bony walls of the orbit share features of bony expansion, facial deformity, and the potential to cause significant orbital and ophthalmic morbidity. We herein present 2 cases of benign mesenchymal tumors with bony involvement in the orbitofacial region (1 juvenile ossifying fibroma and 1 central giant cell granuloma) and review the current management of similar benign fibro-osseous and reactive bone lesions of the orbit. These rare entities presented share common orbital and ophthalmic manifestations and remain without any effective definitive treatment options.
authors.affiliation: Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, Houston, Tex., USA; Ruiz Department of Ophthalmology and Visual Science, The University of Texas Health Science Center at Houston, Houston, Tex., USA.
authors.forename: Helen
authors.initials: H
authors.lastname: Merritt
authors.affiliation: Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, Houston, Tex., USA.
authors.forename: Vivian T
authors.initials: VT
authors.lastname: Yin
authors.affiliation: Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, Houston, Tex., USA; Ruiz Department of Ophthalmology and Visual Science, The University of Texas Health Science Center at Houston, Houston, Tex., USA.
authors.forename: Margaret L
authors.initials: ML
authors.lastname: Pfeiffer
authors.affiliation: Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Tex., USA.
authors.forename: Wei-Lien
authors.initials: WL
authors.lastname: Wang
authors.affiliation: Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, Houston, Tex., USA.
authors.forename: Matthew C
authors.initials: MC
authors.lastname: Sniegowski
authors.affiliation: Orbital Oncology and Ophthalmic Plastic Surgery Program, Department of Plastic Surgery, Houston, Tex., USA.
authors.forename: Bita
authors.initials: B
authors.lastname: Esmaeli
keywords: Central giant cell granuloma; Facial deformity; Fibro-osseous lesions; Juvenile ossifying fibroma; Mesenchymal tumors; Orbital bones; Reactive bone lesions