title: From inflammation to cancer.
abstract: BACKGROUND
  The participation of inflammation in the progression of cancer for many years have been the subject of research.
  
  
  METHODS
  In the 19th century, there was evidence that an acute inflammation may inhibit the development of cancer. However, chronic inflammation affects the progression of the disease.
  
  
  RESULTS
  Today, it is known that inflammation and cancer use similar mechanisms of development such as severe cell proliferation or angiogenesis. It has been shown that prolonged presence of inflammatory cells and factors in the tumor microenvironment can accelerate its growth and inhibit apoptosis of transformed cells.
  
  
  CONCLUSIONS
  In this article we present a brief history of the discovery mechanisms and potential links between acute and chronic inflammation and cancer.
authors.affiliation: Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Ul. Waszyngtona 15A, 15-276, Bialystok, Poland.
authors.forename: A
authors.initials: A
authors.lastname: Korniluk
authors.affiliation: Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Ul. Waszyngtona 15A, 15-276, Bialystok, Poland.
authors.forename: O
authors.initials: O
authors.lastname: Koper
authors.affiliation: Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Ul. Waszyngtona 15A, 15-276, Bialystok, Poland.
authors.forename: H
authors.initials: H
authors.lastname: Kemona
authors.affiliation: Department of Clinical Laboratory Diagnostics, Medical University of Bialystok, Ul. Waszyngtona 15A, 15-276, Bialystok, Poland. piekarskav@yahoo.com.
authors.forename: V
authors.initials: V
authors.lastname: Dymicka-Piekarska
mesh_terms: D017209:Apoptosis; D049109:Cell Proliferation; D018450:Disease Progression; D006801:Humans; D007249:Inflammation / Q000473:pathology*; D009369:Neoplasms / Q000473:pathology*; D009389:Neovascularization, Pathologic / Q000473:pathology
keywords: Acute inflammation; Adhesion molecules; Cancer; Chronic inflammation