title: An Unprecedented High Content of the Bioactive Flavone Tricin in Huperzia Medicinal Species Used by the Saraguro in Ecuador.
abstract: The flavone tricin (5,7,4'-trihydroxy-3',5'-dimethoxyflavone) is considered to be a selective potent inhibitor of different cancer cell lines and a potential colorectal cancer chemopreventive agent. In this paper we describe a reliable UHPLC-UV-ESIMS method for the determination of tricin in Huperzia plants used in the traditional medicine of the Saraguro community living in Southern Ecuador. An unusually high amount of tricin was found in H. brevifolia and H. compacta, which exceeded the content of this flavone determined so far in other plants.
authors.affiliation: Departamento de Química, Universidad Técnica Particular de Loja, San Cayetano Alto s/n, Loja – Ecuador .|Dipartimento di Chimica and CISTRE, Università degli Studi di Pavia, Viale Taramelli 12, 27100, Pavia, Italy.
authors.forename: Chabaco
authors.initials: C
authors.lastname: Armijos
authors.forename: Jorge
authors.initials: J
authors.lastname: Ponce
authors.forename: Jorge
authors.initials: J
authors.lastname: Ramírez
authors.forename: Davide
authors.initials: D
authors.lastname: Gozzini
authors.forename: Paola Vita
authors.initials: PV
authors.lastname: Finzi
authors.forename: Giovanni
authors.initials: G
authors.lastname: Vidari
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004484:Ecuador; D005419:Flavonoids / Q000737:chemistry* / Q000494:pharmacology*; D006801:Humans; D032501:Huperzia / Q000737:chemistry*; D013058:Mass Spectrometry / Q000379:methods; D008519:Medicine, Traditional; D010946:Plants, Medicinal / Q000737:chemistry*; D044382:Population Groups
chemical_list: D005419:Flavonoids; C017769:tricin