title: Sequence determination of a new parrot bornavirus-5 strain in Japan: implications of clade-specific sequence diversity in the regions interacting with host factors.
abstract: In this study, the genome sequence of a new parrot bornavirus-5 (PaBV-5) detected in Eclectus roratus was determined. Phylogenetic analysis showed that the genus Bornavirus is divided into three major clades and that PaBV-5 belongs to clade 2, which contains avian viruses that exhibit infectivity to mammalian cells. Sequence comparisons of the regions known to interact with host factors indicated that the clade 2 avian viruses possess sequences intermediate between the clade 1 mammalian viruses and the clade 3 avian viruses, suggesting that the identified regions might contribute to the differences in virological properties between the three clades.
authors.affiliation: Department of Viral Oncology, Institute for Virus Research.|Department of Mammalian Regulatory Network, Graduate School of Biostudies.
authors.forename: Ryo
authors.initials: R
authors.lastname: Komorizono
authors.affiliation: Department of Viral Oncology, Institute for Virus Research.|Center for Emerging Virus Research, Institute for Virus Research, Kyoto University.
authors.forename: Akiko
authors.initials: A
authors.lastname: Makino
authors.affiliation: Transboundary Animal Diseases Research Center, Joint Faculty of Veterinary Medicine, Kagoshima University.|United Graduate School of Veterinary Science, Yamaguchi University, Yamaguchi.
authors.forename: Masayuki
authors.initials: M
authors.lastname: Horie
authors.affiliation: Department of Viral Oncology, Institute for Virus Research.|Department of Mammalian Regulatory Network, Graduate School of Biostudies.
authors.forename: Tomoyuki
authors.initials: T
authors.lastname: Honda
authors.affiliation: Department of Viral Oncology, Institute for Virus Research.|Department of Mammalian Regulatory Network, Graduate School of Biostudies.|Department of Tumor Viruses, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
authors.forename: Keizo
authors.initials: K
authors.lastname: Tomonaga
mesh_terms: D000818:Animals; D001483:Base Sequence; D001715:Bird Diseases / Q000821:virology; D028981:Bornaviridae / Q000737:chemistry / Q000145:classification / Q000235:genetics*; D016679:Genome, Viral; D007564:Japan; D010311:Parrots / Q000821:virology*; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017421:Sequence Analysis; D017422:Sequence Analysis, DNA
chemical_list: D012367:RNA, Viral
keywords: Avian bornavirus; host factors; phylogenetic analysis