title: Single-session alcohol sclerotherapy of symptomatic liver cysts using 10-20 min of ethanol exposure: no recurrence at 2-16 years of follow-up.
abstract: To assess long-term results after single-session alcohol sclerotherapy of symptomatic benign liver cysts performed with maximum 20 min of exposure to alcohol.
  
  
  
  We included 47 patients aged 32-88 years (42 women, 5 men) with 51 benign non-parasitic liver cysts that were exposed to ethanol for 7-20 min in a single sclerotherapy session and were followed for at least 24 months. Each cyst was emptied before injecting ethanol (10% of cyst volume, but maximum 100 mL) into it. The patient rotated from side to side to facilitate contact between ethanol and the whole cyst wall. Pre-treatment cyst volume was defined as the volume of aspirated cyst fluid after complete emptying of the cyst. Follow-up cyst volume was estimated based on computed tomography images.
  
  
  
  Cyst volumes were 30-4900 (median 520) mL at pre-treatment and 0-230 (median 1) mL at 24-193 (median 56) months follow-up, a reduction of 83-100% (median 99.7%). No cyst required repeated treatment during the follow-up. Median volume reduction was 99.7% at median 49 months of follow-up for 35 cysts exposed to ethanol for 7-10 min vs. 99.6% at median 75 months of follow-up for 16 cysts exposed for 20 min (p = 0.83, Mann-Whitney test). Ethanol intoxication occurred in one patient. There were no other complications except for pain.
  
  
  
  Long-term results of single-session alcohol sclerotherapy performed with maximum 20 min of exposure to ethanol were satisfactory with no sign of recurrence of cyst fluid.
authors.affiliation: Department of Radiology, Haukeland University Hospital, Jonas Liesvei 65, 5021, Bergen, Norway.|Department of Clinical Medicine, University of Bergen, Pb 7804, 5020, Bergen, Norway.
authors.forename: Trond Bjerke
authors.initials: TB
authors.lastname: Larssen
authors.affiliation: Department of Clinical Medicine, University of Bergen, Pb 7804, 5020, Bergen, Norway.|Department of Acute and Gastrointestinal Surgery, Haukeland University Hospital, Jonas Liesvei 65, 5021, Bergen, Norway.
authors.forename: Asgaut
authors.initials: A
authors.lastname: Viste
authors.affiliation: Department of Acute and Gastrointestinal Surgery, Haukeland University Hospital, Jonas Liesvei 65, 5021, Bergen, Norway.
authors.forename: Arild
authors.initials: A
authors.lastname: Horn
authors.affiliation: Department of Radiology, Haukeland University Hospital, Jonas Liesvei 65, 5021, Bergen, Norway.|Department of Clinical Medicine, University of Bergen, Pb 7804, 5020, Bergen, Norway.
authors.forename: Ingfrid Salvesen
authors.initials: IS
authors.lastname: Haldorsen
authors.affiliation: Department of Radiology, Haukeland University Hospital, Jonas Liesvei 65, 5021, Bergen, Norway. ansgar.espeland@gmail.com.|Department of Clinical Medicine, University of Bergen, Pb 7804, 5020, Bergen, Norway. ansgar.espeland@gmail.com.
authors.forename: Ansgar
authors.initials: A
authors.lastname: Espeland
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003560:Cysts; D000431:Ethanol; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008104:Liver Cirrhosis, Alcoholic; D008297:Male; D008875:Middle Aged; D012597:Sclerosing Solutions; D015911:Sclerotherapy; D016896:Treatment Outcome
chemical_list: D012597:Sclerosing Solutions; D000431:Ethanol
keywords: Cysts; Ethanol; Liver diseases; Sclerotherapy; Treatment outcome