title: Starving Intestinal Inflammation with the Amino Acid Sensor GCN2.
abstract: Metabolic stressors are emerging as important controls over immune system function. In a recent paper, Ravindran et al. (2016) uncovered a novel mechanism by which an amino acid sensing pathway controls inflammation in the gut.
authors.affiliation: Diabetes Research Group, Division of Cellular & Molecular Biology, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON M5G 1L7, Canada.
authors.forename: Xavier S
authors.initials: XS
authors.lastname: Revelo
authors.affiliation: Diabetes Research Group, Division of Cellular & Molecular Biology, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON M5G 1L7, Canada; Department of Laboratory Medicine, St. Michael's Hospital, Toronto, ON M5B 1W8, Canada.
authors.forename: Shawn
authors.initials: S
authors.lastname: Winer
authors.affiliation: Diabetes Research Group, Division of Cellular & Molecular Biology, Toronto General Research Institute (TGRI), University Health Network, Toronto, ON M5G 1L7, Canada; Department of Pathology, University Health Network, Toronto, ON M5G 2C4, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON M5S 1A8, Canada; Department of Immunology, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: dan.winer@uhn.ca.
authors.forename: Daniel A
authors.initials: DA
authors.lastname: Winer
mesh_terms: D000596:Amino Acids / Q000378:metabolism*; D000818:Animals; D001343:Autophagy; D007249:Inflammation / Q000378:metabolism / Q000473:pathology*; D007413:Intestinal Mucosa / Q000378:metabolism; D007422:Intestines / Q000473:pathology*; D051379:Mice; D008954:Models, Biological; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism*
chemical_list: D000596:Amino Acids; C070634:Eif2ak4 protein, mouse; D017346:Protein Serine-Threonine Kinases