title: [Peranal bleeding and elevated liver function tests in a 33‑year-old refugee from Nigeria].
abstract: A 33-year-old refugee from Nigeria, who had been living in Germany for 1 year, was admitted to the hospital due to pelvic pain, peranal hemorrhage, and an unexplained increase in transaminase levels. As the liver screening tests, sonography findings, and colonoscopy were normal, a liver biopsy was performed that revealed Schistosoma mansoni worm eggs as an unexpected diagnostic finding. Serological tests for specific antibodies and parasitological egg detection in the stool confirmed the diagnosis. After only temporary response to a short-term and low-dose treatment with praziquantel, a 3-day high-dose (40 mg/kg body weight) treatment with praziquantel finally led to long-lasting symptom relief.
authors.affiliation: Medizinische Klinik II, Donauisar Klinikum, Perlasberger Str. 41, 94469, Deggendorf, Deutschland. nikola.argirovic@donau-isar-klinikum.de.
authors.forename: N
authors.initials: N
authors.lastname: Argirovic
authors.affiliation: Medizinische Klinik II, Donauisar Klinikum, Perlasberger Str. 41, 94469, Deggendorf, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Caselitz
authors.affiliation: Institut für Pathologie und Zytologie, Donauisar Klinikum, Deggendorf, Deutschland.
authors.forename: W
authors.initials: W
authors.lastname: Mohren
authors.affiliation: Institut für Pathologie und Zytologie, Donauisar Klinikum, Deggendorf, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Cruz Cordero
authors.affiliation: Institut für Laboratoriumsdiagnostik und Transfusionsmedizin, Donauisar Klinikum, Deggendorf, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Huber
authors.affiliation: Medizinische Klinik II, Donauisar Klinikum, Perlasberger Str. 41, 94469, Deggendorf, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Wagner
mesh_terms: D000328:Adult; D000871:Anthelmintics / Q000627:therapeutic use; D001004:Anus Diseases / Q000150:complications / Q000175:diagnosis* / Q000517:prevention & control; D003937:Diagnosis, Differential; D006470:Hemorrhage / Q000150:complications / Q000175:diagnosis* / Q000517:prevention & control; D006801:Humans; D008107:Liver Diseases / Q000150:complications / Q000175:diagnosis* / Q000517:prevention & control; D008111:Liver Function Tests; D008297:Male; D009549:Nigeria; D011223:Praziquantel / Q000008:administration & dosage*; D012036:Refugees; D012555:Schistosomiasis mansoni / Q000150:complications / Q000175:diagnosis* / Q000188:drug therapy*; D013812:Therapeutics; D000637:Transaminases / Q000097:blood
chemical_list: D000871:Anthelmintics; D011223:Praziquantel; D000637:Transaminases
keywords: Biopsy, liver; Hematochezia; Recurrence, Schistosoma mansoni; Schistosomiasis; Serologic tests