title: Inherited renal cystic diseases.
abstract: A number of inherited renal diseases present with renal cysts and often lead to end-stage renal disease. With recent advances in genetics, increasing number of genes and mutations have been associated with cystic renal diseases. Although genetic testing can provide a definite diagnosis, it is often reserved for equivocal cases or for ongoing investigational research. Therefore, imaging findings are essential in the routine diagnosis, follow-up, and detection of complications in patients with inherited cystic renal diseases. In this article, the most recent classification, genetic analysis, clinical presentations, and imaging findings of inherited cystic renal diseases will be discussed.
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 1st Street, SW, Rochester, MN, 55905, USA. kim.bohyun@mayo.edu.
authors.forename: Bohyun
authors.initials: B
authors.lastname: Kim
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 1st Street, SW, Rochester, MN, 55905, USA.
authors.forename: Bernard F
authors.initials: BF
authors.lastname: King
authors.affiliation: Department of Radiology, Mayo Clinic College of Medicine, 200 1st Street, SW, Rochester, MN, 55905, USA.
authors.forename: Terri J
authors.initials: TJ
authors.lastname: Vrtiska
authors.affiliation: Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 1st Street, SW, Rochester, MN, 55905, USA.
authors.forename: Maria V
authors.initials: MV
authors.lastname: Irazabal
authors.affiliation: Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 1st Street, SW, Rochester, MN, 55905, USA.
authors.forename: Vicente E
authors.initials: VE
authors.lastname: Torres
authors.affiliation: Division of Nephrology and Hypertension, Mayo Clinic College of Medicine, 200 1st Street, SW, Rochester, MN, 55905, USA.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Harris
mesh_terms: D003937:Diagnosis, Differential; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing; D006801:Humans; D052177:Kidney Diseases, Cystic / Q000000981:diagnostic imaging* / Q000235:genetics*
keywords: Cystic renal disease; Hereditary renal disease; Imaging; Polycystic kidney disease