title: Unprecedented selectivity in molecular recognition of carbohydrates by a metal-organic framework.
abstract: Metal-organic framework (MOF) material NU-1000 adsorbs dimers cellobiose and lactose from aqueous solution, in amounts exceeding 1250 mg gNU-1000(-1) while completely excluding the adsorption of the monomer glucose, even in a competitive mode with cellobiose. The MOF also discriminates between dimers consisting of α and β linkages, showing no adsorption of maltose. Electronic structure calculations demonstrate that key to this selective molecular recognition is the number of favorable CH-π interactions made by the sugar with pyrene units of the MOF.
authors.affiliation: Department of Chemical and Biomolecular Engineering, University of California, Berkeley, California 94720, USA. askatz@berkeley.edu.
authors.forename: Mizuho
authors.initials: M
authors.lastname: Yabushita
authors.forename: Peng
authors.initials: P
authors.lastname: Li
authors.forename: Varinia
authors.initials: V
authors.lastname: Bernales
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Atsushi
authors.initials: A
authors.lastname: Fukuoka
authors.forename: Laura
authors.initials: L
authors.lastname: Gagliardi
authors.forename: Omar K
authors.initials: OK
authors.lastname: Farha
authors.forename: Alexander
authors.initials: A
authors.lastname: Katz
mesh_terms: D000327:Adsorption; D002241:Carbohydrates / Q000032:analysis*; D005947:Glucose / Q000737:chemistry*; D000073396:Metal-Organic Frameworks / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D002241:Carbohydrates; D000073396:Metal-Organic Frameworks; D005947:Glucose