title: Precursor B cell lymphoblastic lymphoma presenting as periorbital swelling.
abstract: An 11-year-old girl was admitted for further investigation as to the cause of her bilateral papilloedema and periorbital swelling. She had a 2-week history of headache and unilateral eyelid swelling, and a 2-day history of right-sided groin swelling. CT and MRI scans revealed soft tissue adjacent to the lateral orbital walls within the extraconal lateral aspects of both orbits, more on the right than the left. The scans also revealed extensive lymphadenopathy above and below the diaphragm. The patient underwent bone marrow studies and biopsy of the lymph node in her groin. The results revealed normal bone marrow with no evidence of malignancy. The lymph node histology confirmed malignant lymphoma in keeping with B cell lymphoblastic lymphoma. The patient was started on the UKALL 2011 chemotherapy trial.
authors.affiliation: Royal Belfast Hospital for Sick Children, Belfast, UK.
authors.forename: Niamh
authors.initials: N
authors.lastname: Galway
authors.affiliation: Department of Paediatric Oncology, Royal Belfast Hospital for Sick Children, Belfast, UK.
authors.forename: Robert
authors.initials: R
authors.lastname: Johnston
authors.affiliation: Department of Paediatric Oncology, Royal Belfast Hospital for Sick Children, Belfast, UK.
authors.forename: Carole
authors.initials: C
authors.lastname: Cairns
authors.affiliation: Department of Paediatrics, Royal Belfast Hospital for Sick Children, Belfast, UK.
authors.forename: Andrew James
authors.initials: AJ
authors.lastname: Thompson
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage* / Q000627:therapeutic use; D002648:Child; D005134:Eye Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000473:pathology; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology; D008279:Magnetic Resonance Imaging / Q000379:methods; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000473:pathology; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome