title: Self-assembly of high-nuclearity lanthanide-based nanoclusters for potential bioimaging applications.
abstract: Two series of Cd-Ln and Ni-Ln clusters [Ln8Cd24L12(OAc)44(48)Cl4(0)] and [Ln8Ni6L6(OAc)24(EtOH)6(H2O)2] were constructed using a flexible ligand. The Cd-Ln clusters exhibit interesting nano-drum-like structures which allows direct visualization by TEM. Luminex MicroPlex Microspheres loaded with the Cd-Sm cluster were visualized using epifluorescence microscopy. Cytotoxicity studies on A549 and AGS cancer cell lines showed that the materials have mild to moderate cytotoxicity.
authors.affiliation: College of Chemistry and Materials Engineering, Wenzhou University, Wenzhou 325035, China.
authors.forename: Xiaoping
authors.initials: X
authors.lastname: Yang
authors.forename: Shiqing
authors.initials: S
authors.lastname: Wang
authors.forename: Desmond
authors.initials: D
authors.lastname: Schipper
authors.forename: Lijie
authors.initials: L
authors.lastname: Zhang
authors.forename: Zongping
authors.initials: Z
authors.lastname: Li
authors.forename: Shaoming
authors.initials: S
authors.lastname: Huang
authors.forename: Daqiang
authors.initials: D
authors.lastname: Yuan
authors.forename: Zhongning
authors.initials: Z
authors.lastname: Chen
authors.forename: Annie J
authors.initials: AJ
authors.lastname: Gnanam
authors.forename: Justin W
authors.initials: JW
authors.lastname: Hall
authors.forename: Tyler L
authors.initials: TL
authors.lastname: King
authors.forename: Emily
authors.initials: E
authors.lastname: Que
authors.forename: Yakhya
authors.initials: Y
authors.lastname: Dieye
authors.forename: Jamuna
authors.initials: J
authors.lastname: Vadivelu
authors.forename: Katherine A
authors.initials: KA
authors.lastname: Brown
authors.forename: Richard A
authors.initials: RA
authors.lastname: Jones
mesh_terms: D000072283:A549 Cells; D045744:Cell Line, Tumor; D018360:Crystallography, X-Ray; D006801:Humans; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008024:Ligands; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry*
chemical_list: D028581:Lanthanoid Series Elements; D008024:Ligands