title: Copper-Catalyzed Carbonylative Coupling of Cycloalkanes and Amides.
abstract: Carbonylation reactions are a most powerful method for the synthesis of carbonyl-containing compounds. However, most known carbonylation procedures still require noble-metal catalysts and the use of activated compounds and good nucleophiles as substrates. Herein, we developed a copper-catalyzed carbonylative transformation of cycloalkanes and amides. Imides were prepared in good yields by carbonylation of a C(sp(3) )-H bond of the cycloalkane with the amides acting as weak nucleophiles. Notably, this is the first report of copper-catalyzed carbonylative C-H activation.
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Yahui
authors.initials: Y
authors.lastname: Li
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Kaiwu
authors.initials: K
authors.lastname: Dong
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Fengxiang
authors.initials: F
authors.lastname: Zhu
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany.
authors.forename: Zechao
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Leibniz-Institut für Katalyse e.V. an der Universität Rostock, Albert-Einstein-Strasse 29a, 18059, Rostock, Germany. Xiao-Feng.Wu@catalysis.de.|Department of Chemistry, Zhejiang Sci-Tech University, Xiasha Campus, Hangzhou, 310018, P.R. China. Xiao-Feng.Wu@catalysis.de.
authors.forename: Xiao-Feng
authors.initials: XF
authors.lastname: Wu
keywords: amides; carbonylation; copper catalysis; cycloalkanes; imides