title: Malignant Peripheral Nerve Sheath Tumor of the Infraorbital Nerve.
abstract: The objective of this study is to report a large, rare, and ulcerative infiltrated skin lesion. Its diagnosis, therapeutic management, and progress are described. The patient is a 78-year-old white man, who presented with a 12-month ulcerative perforated lesion that had affected and infiltrated the skin, with easy bleeding. He had a history of hypertension, although controlled, was a 40-year smoker, had chronic atrial fibrillation, diabetes, and microangiopathy. During the consultation, the patient also presented with ocular obstruction due to an inability to open the eye. He mentioned having reduced vision. The computed tomography scan showed upper maxilla osteolysis without eye involvement. We underwent a radical resection in which upper maxilla and the anterior orbital margin were included. We used a Becker-type flap that allowed us to rebuild the cheek and to complete a modified neck dissection. Progress was favorable; the patient recovered ocular motility and his vision improved to 20/200. The final biopsy result was "malignant peripheral nerve sheath tumor, malignant schwannoma." Malignant schwannoma of the peripheral nerve is extremely rare. The total resection and reconstruction being completed in one surgery represented a challenge due to the difficulty in obtaining tissues in addition to the necessity of an oncological resection.
authors.affiliation: General Surgery and Head and Neck Division, Vicente López Public Hospital, Buenos Aires, Argentina.
authors.forename: José Luis
authors.initials: JL
authors.lastname: D'Addino
authors.affiliation: Division of General Surgery, Vicente López Public Hospital, Buenos Aires, Argentina.
authors.forename: Laura
authors.initials: L
authors.lastname: Piccoletti
authors.affiliation: Division of Head and Neck Surgery, Vicente López Public Hospital, Buenos Aires, Argentina.
authors.forename: María Mercedes
authors.initials: MM
authors.lastname: Pigni
authors.affiliation: Division of Head and Neck Surgery, Vicente López Public Hospital, Buenos Aires, Argentina.
authors.forename: Maria José Rodriguez Arenas
authors.initials: MJ
authors.lastname: de Gordon
keywords: cheek reconstruction; malignant schwannoma; peripheral nerve sheath tumor; schwannoma