title: Undifferentiated sarcoma originating from the mitral valve: a case report.
abstract: BACKGROUND
  Primary cardiac sarcomas are quite uncommon. Among them, sarcomas originating from the mitral valve are exceedingly rare. They are often misdiagnosed due to non-specific symptoms. The prognosis of cardiac sarcomas remains poor, and finding a more effective therapy poses a big challenge for the doctors. Currently, complete surgical resection of the tumor is still the most popular treatment in cases that without metastases.
  
  
  METHODS
  A 38-year-old female was transported to our department with persistent cough and chest pain. The operation of mitral valve replacement was scheduled after a provisional diagnosis of serious mitral stenosis. During the operation, we found that a large polypoid mass infiltrating mainly the mitral valve and part of the left atria. We removed the tumor as completely as possible and replaced the mitral valve. Histology confirmed the diagnosis of undifferentiated sarcoma after operation. The patient was asymptomatic with no recurrence at 3-month follow-up.
  
  
  CONCLUSIONS
  Primary cardiac sarcomas is a rare and the prognosis is poor. The sarcomas is often found by chance during the operation. Surgical operation need to be carried out directly.
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
authors.forename: Haibin
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
authors.forename: Weitie
authors.initials: W
authors.lastname: Wang
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Li
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
authors.forename: Zhicheng
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
authors.forename: Tiance
authors.initials: T
authors.lastname: Wang
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China.
authors.forename: Rihao
authors.initials: R
authors.lastname: Xu
authors.affiliation: Department of Cardiovascular Surgery, 2nd Hospital of Bethune, Jilin University, Changchun, Jilin, China. kxliu64@hotmail.com.
authors.forename: Kexiang
authors.initials: K
authors.lastname: Liu
mesh_terms: D000328:Adult; D003371:Cough / Q000209:etiology; D003937:Diagnosis, Differential; D004417:Dyspnea / Q000209:etiology; D005260:Female; D006338:Heart Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D008943:Mitral Valve / Q000601:surgery; D012509:Sarcoma / Q000150:complications / Q000175:diagnosis* / Q000601:surgery
keywords: Cardiac surgery; Cardiac tumors; Pathology; Sarcoma