title: Biomimicking Nano-Micro Binary Polymer Brushes for Smart Cell Orientation and Adhesion Control.
abstract: A new biomimetic surface named nano-micro binary polymer brushes is fabricated by large-area bench-top dip-pen nanodisplacement lithography technique. It is composed of gelatin-modified poly(glycidyl methacrylate) nanolines which are spaced by microstripes of poly(N-isopropylacrylamide). Cells are not only adhered and oriented well on the re-used surface, but also detachable from the surface with well-preserved extracellular matrix and aligned morphology.
authors.affiliation: Nanotechnology Centre, Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR, China.
authors.forename: Lina
authors.initials: L
authors.lastname: Chen
authors.affiliation: Nanotechnology Centre, Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR, China.|Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208, USA.
authors.forename: Zhuang
authors.initials: Z
authors.lastname: Xie
authors.affiliation: Faculty of Materials Science and Engineering, South China University of Technology, Guangzhou, 510640, China.
authors.forename: Tiansheng
authors.initials: T
authors.lastname: Gan
authors.affiliation: Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Faculty of Materials Science and Engineering, South China University of Technology, Guangzhou, 510640, China.
authors.forename: Guangzhao
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Department of Chemistry and International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL, 60208, USA.
authors.forename: Chad A
authors.initials: CA
authors.lastname: Mirkin
authors.affiliation: Nanotechnology Centre, Institute of Textiles and Clothing, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, SAR, China.
authors.forename: Zijian
authors.initials: Z
authors.lastname: Zheng
mesh_terms: D000178:Acrylamides / Q000737:chemistry; D000180:Acrylic Resins / Q000737:chemistry; D032701:Biomimetics / Q000379:methods*; D004852:Epoxy Compounds / Q000737:chemistry; D008689:Methacrylates / Q000737:chemistry; D049329:Nanostructures / Q000737:chemistry; D011108:Polymers / Q000737:chemistry*; D013499:Surface Properties
chemical_list: D000178:Acrylamides; D000180:Acrylic Resins; D004852:Epoxy Compounds; D008689:Methacrylates; D011108:Polymers; C052970:poly-N-isopropylacrylamide; C067295:N-isopropylacrylamide; C007870:glycidyl methacrylate
keywords: bio-nano interfaces; cell adhesion; cell orientation; dip-pen nanolithography; polymer brushes