title: Surgical treatment of cardiac tumors: a 5-year experience from a single cardiac center.
abstract: BACKGROUND
  Cardiac tumors are rare but manifested with various clinical presentations and often cause unexpected symptoms or sudden death. The objective is to review the clinical presentation, histopathological spectrum, mortality and follow-up data of patients with cardiac tumors following surgery treatment over a period of 5 years.
  
  
  METHODS
  We retrospectively collected the medical records of all patients diagnosed of cardiac tumors in the period between January 2008 and December 2013 at the cardiac center of our university. Clinical histories, perioperative data, surgical findings, efficacy and follow-up data were reviewed in our study. Patients were divided into two groups according to site distribution of the tumors in the heart.
  
  
  RESULTS
  A total of 131 patients underwent surgical treatment of cardiac tumors were enrolled in this study, with a mean age of 51.39±16.37. The result of analysis showed that 79.47% (n=104) of the primary intracardiac tumors were benign, while primary malignant neoplasms accounted for 16.03% (n=21) of all patients, with the remainder (n=6, 4.6%) metastatic tumors transferred from other organs. Among all patients there were 2 in-hospital deaths and the survival rate in all patients at 1-year, 3-year and 5-year follow up was 83.20%, 78.62% and 66.41% respectively. Both patients with tumors in the left and right heart had similar basic characteristics except sex gender (P=0.002), BSA (P=0.045) and weight (P=0.033). Compared with patients with tumors in the right heart, patients with tumors in the left heart had significant higher CPB time (P<0.001), cross clamp time (P<0.001) and time of mechanical ventilation (P<0.001), and they also had longer ICU stay (P<0.001) but not total hospital stay (P=0.434).
  
  
  CONCLUSIONS
  Surgical resection represents an effective protocol in treating cardiac tumors. Data in our study of cardiac tumors on frequency and allocation were consistent with previous reports which may provide useful clinical evidence on shared data, and data revealed that patients with malignant cardiac tumors had significant lower survival both in hospital and long-term follow-up.
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Liang
authors.initials: L
authors.lastname: Yin
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Dengke
authors.initials: D
authors.lastname: He
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Shen
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Ling
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Xue
authors.affiliation: Department of Cardiothoracic Surgery, Changzheng Hospital, the Second Military Medical University, Shanghai 200003, China.
authors.forename: Zhinong
authors.initials: Z
authors.lastname: Wang
keywords: Cardiac tumors; effect; neoplasm; surgery