title: [Non-compliance with the systemic antibiotic treatment prescribed in Primary Health Care emergency departments (Study INCUMAT')].
abstract: BACKGROUND
  Non-compliance with antibiotics treatment has severe consequences. Although antibiotics are commonly prescribed drugs, there are few studies that evaluate therapeutic compliance in acute diseases. The main objective of this study is to determine the percentage of non-compliance with the systemic antibiotics treatment prescribed in emergency departments.
  
  
  METHODS
  A prospective observational study was performed in the Emergency Department of 2 health centres of the Cantabria Health Service between the months of June and September 2014. The study included patients of any age, and those could be monitored, who were prescribed a systemic antibiotic for any infectious disease. Sociodemographic variables, diseases, and compliance were the variables studied. The Morinsky-Green test was used, plus 3 questions added by the authors.
  
  
  RESULTS
  Of the 303 patients included, non-compliance, evaluated using the Morinsky-Green test, was 32.7% (95% CI 27.6-38.1), with this rising to the 44.9% (95% CI 39.4-50.5) when the 3 mentioned questions were added to the test. A downward trend is observed in non-compliance as the age increases. The risk of non-compliance is twice in men than in women: OR=2.02 (95% CI 1.27-3.24).
  
  
  CONCLUSIONS
  Almost half (45%) of the patients who are prescribed antibiotics do not comply with the indications. Most of them attribute this fact to forgetfulness in compliance with the prescribed treatment. The elderly and women follow the treatment better, which should be taken into account when designing strategies to improve therapeutic compliance.
authors.affiliation: Servicio de Urgencias de Atención Primaria (SUAP) de Colindres, Servicio Cántabro de Salud (SCS), Colindres, Cantabria, España. Electronic address: evamaria.vega@scsalud.es.
authors.forename: E M
authors.initials: EM
authors.lastname: Vega-Cubillo
authors.affiliation: Servicio de Urgencias de Atención Primaria (SUAP) de Colindres, Servicio Cántabro de Salud (SCS), Colindres, Cantabria, España.
authors.forename: J M
authors.initials: JM
authors.lastname: Andrés-Carreira
authors.affiliation: Servicio de Urgencias de Atención Primaria (SUAP) de Santoña, Servicio Cántabro de Salud (SCS), Santoña, Cantabria, España.
authors.forename: S
authors.initials: S
authors.lastname: Cirillo-Ibargüen
authors.affiliation: Servicio de Urgencias de Atención Primaria (SUAP) de Santoña, Servicio Cántabro de Salud (SCS), Santoña, Cantabria, España.
authors.forename: C
authors.initials: C
authors.lastname: Manzanares-Arnaiz
authors.affiliation: Servicio de Urgencias de Atención Primaria (SUAP) de Colindres, Servicio Cántabro de Salud (SCS), Colindres, Cantabria, España.
authors.forename: G
authors.initials: G
authors.lastname: Moreno-Moreno
authors.affiliation: Centro de Salud Vargas, Servicio Cántabro de Salud (SCS), Santander, Cantabria, España.
authors.forename: C G
authors.initials: CG
authors.lastname: Redondo-Figuero
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D001424:Bacterial Infections / Q000188:drug therapy*; D002648:Child; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011320:Primary Health Care; D011446:Prospective Studies; D012737:Sex Factors; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D000900:Anti-Bacterial Agents
keywords: Adherencia terapéutica; Antibiotic; Antibiótico; Atención Primaria; Emergency; Incumplimiento terapéutico; Primary Care; Therapeutic adherence; Therapeutic non-compliance; Urgencias