title: Molecular Imaging of Inflammation: Current Status.
abstract: The ability to image inflammation in vivo can improve our understanding of the pathophysiology underlying various disease etiologies, including cancer, atherosclerosis, and neurodegeneration. A great wealth of preclinical and translational research has been and is currently being developed to decipher the involvement of the immune system in disease pathophysiology, quantify the course of a disease, and visualize the potential detrimental effects of excessive inflammation. Down the road, the ultimate goal is to have clinical noninvasive in vivo imaging biomarkers of inflammation that will help diagnose disease, establish prognosis, and gauge response to preventative and therapeutic strategies.
authors.affiliation: Center for Infectious Disease Imaging, Radiology and Imaging Sciences, National Institutes of Health, Bethesda, Maryland hammoudd@cc.nih.gov.
authors.forename: Dima A
authors.initials: DA
authors.lastname: Hammoud
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D006801:Humans; D007249:Inflammation / Q000000981:diagnostic imaging* / Q000276:immunology*; D018836:Inflammation Mediators / Q000276:immunology*; D007962:Leukocytes / Q000276:immunology*; D057054:Molecular Imaging / Q000639:trends*
chemical_list: D015415:Biomarkers; D018836:Inflammation Mediators
keywords: MRI; PET; inflammation; iron oxide nanoparticles; molecular imaging