title: [Comparative Analysis of the Effectiveness of STR and SNP Markers for Intraspecific and Interspecific Differentiation of the Genus Ovis].
abstract: A comparative study of the informativeness of SNP and STR markers for interspecific and intraspecific differentiation of the two species of the genus Ovis, snow sheep (O. nivicola) and domestic sheep (O. aries), was conducted. Eleven STR loci combined into two multiplex panels were examined. SNP analysis was performed with the DNA microarray OvineSNP50K BeadChip featuring 54241 SNPs. The possibility of clear differentiation of the studied Ovis species with both types of genetic markers was demonstrated. The advantages of SNP markers for intraspecific differentiation of the O. aries breeds and O. nivicola geographical groups were revealed. The areas of application of the studied types of DNA markers are discussed.
authors.forename: T E
authors.initials: TE
authors.lastname: Deniskova
authors.forename: A A
authors.initials: AA
authors.lastname: Sermyagin
authors.forename: V A
authors.initials: VA
authors.lastname: Bagirov
authors.forename: I M
authors.initials: IM
authors.lastname: Okhlopkov
authors.forename: E A
authors.initials: EA
authors.lastname: Gladyr
authors.forename: R V
authors.initials: RV
authors.lastname: Ivanov
authors.forename: G
authors.initials: G
authors.lastname: Brem
authors.forename: N A
authors.initials: NA
authors.lastname: Zinovieva
mesh_terms: D000818:Animals; D005819:Genetic Markers; D018895:Microsatellite Repeats / Q000235:genetics*; D010802:Phylogeny; D020641:Polymorphism, Single Nucleotide / Q000235:genetics*; D034561:Sheep, Domestic / Q000235:genetics*; D013045:Species Specificity
chemical_list: D005819:Genetic Markers