title: Source-specific workplace social support and high-sensitivity C-reactive protein levels among Japanese workers: A 1-year prospective cohort study.
abstract: This study investigated the prospective association between source-specific workplace social support and high-sensitivity C-reactive protein (hs-CRP) levels in workers in Japan.
  
  
  
  We conducted a 1-year prospective cohort study with 1,487 men and 533 women aged 18-65 years. Participants worked at two manufacturing worksites in Japan and were free of major illness. We used multivariable linear regression analyses to evaluate the prospective association between supervisor and coworker support at baseline, and hs-CRP levels at follow-up. We conducted the analyses separately for men and women.
  
  
  
  For women, high supervisor support at baseline was significantly associated with lower hs-CRP levels at follow-up (β = -0.109, P < 0.01), whereas coworker support at baseline was not significantly associated with hs-CRP levels at follow-up. Associations between supervisor and coworker support and hs-CRP levels were not significant for men.
  
  
  
  Supervisor support may have beneficial effects on inflammatory markers in working women. Am. J. Ind. Med. 59:676-684, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Public Health, Kitasato University School of Medicine, Sagamihara, Japan.
authors.forename: Hisashi
authors.initials: H
authors.lastname: Eguchi
authors.affiliation: Department of Mental Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Akihito
authors.initials: A
authors.lastname: Shimazu
authors.affiliation: Department of Mental Health, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Norito
authors.initials: N
authors.lastname: Kawakami
authors.affiliation: Department of Mental Health, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan, Kitakyushu, Japan.
authors.forename: Akiomi
authors.initials: A
authors.lastname: Inoue
authors.affiliation: Department of Public Health, Kitasato University School of Medicine, Sagamihara, Japan.
authors.forename: Akizumi
authors.initials: A
authors.lastname: Tsutsumi
mesh_terms: D000293:Adolescent; D000328:Adult; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007249:Inflammation / Q000097:blood; D007564:Japan; D016014:Linear Models; D008297:Male; D066192:Manufacturing Industry; D008875:Middle Aged; D015999:Multivariate Analysis; D009784:Occupational Diseases / Q000097:blood* / Q000523:psychology; D011446:Prospective Studies; D012737:Sex Factors; D012944:Social Support; D013315:Stress, Psychological / Q000097:blood* / Q000523:psychology; D017132:Workplace / Q000523:psychology*; D055815:Young Adult
chemical_list: D015415:Biomarkers; D002097:C-Reactive Protein
keywords: C-reactive protein; cardiovascular disease; inflammation; prospective studies; workplace social support