title: Application of Advanced MR Imaging Techniques and the Evolving Role of PET/MR Imaging in Neuro-oncology.
abstract: A requisite to achieve a better outcome in patients with high-grade glioma is the development of noninvasive imaging techniques that improve tumor detection, delineation, and grading, before, during, and after therapy. This article reviews the value of a selection of important advanced MR imaging techniques (diffusion-weighted MR imaging, diffusion-tensor imaging, perfusion MR imaging, and MR spectroscopy) and the evolving role of positron emission tomography (PET)/MR imaging in the evaluation of high-grade gliomas in various settings. This review introduces the reader to the basic principles and clinical applications of these advanced MR imaging and PET/MR imaging techniques.
authors.affiliation: Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands. Electronic address: thomaskwee@gmail.com.
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Kwee
authors.affiliation: Department of Radiology and Nuclear Medicine, University Medical Center Utrecht, Heidelberglaan 100, Utrecht 3584 CX, The Netherlands.
authors.forename: Maarten L
authors.initials: ML
authors.lastname: Donswijk