title: Stereotactic radiosurgery for intracranial metastases: linac-based and gamma-dedicated unit approach.
abstract: BACKGROUND
  For intracranial metastases, the role of stereotactic radiosurgery (SRS) or fractionated stereotactic radiotherapy is well recognized.
  
  
  METHODS
  Historically, the first technology, for stereotactic device able to irradiate a brain tumor volume, was Gamma Knife® (GK). Due to the technological advancement of linear accelerator (Linac), there was a continuous increasing interest in SRS Linac-based applications. In those decades, it was assumed a superiority of GK compared to SRS Linac-based for brain tumor in terms of dose conformity and rapid fall-off dose close to the target. Expert commentary: Recently, due to the Linac technologic advancement, the choice of SRS GK-based is not necessarily so exclusive. The current review discussed in details the technical and clinical aspects comparing the two approaches for brain metastases.
authors.affiliation: a Radiation Oncology Department , Sacro Cuore Hospital , Negrar , Italy.
authors.forename: Filippo
authors.initials: F
authors.lastname: Alongi
authors.affiliation: a Radiation Oncology Department , Sacro Cuore Hospital , Negrar , Italy.
authors.forename: Alba
authors.initials: A
authors.lastname: Fiorentino
authors.affiliation: b Radiation Oncology Department , Istituto Clinico Humanitas , Milan , Italy.
authors.forename: Pietro
authors.initials: P
authors.lastname: Mancosu
authors.affiliation: b Radiation Oncology Department , Istituto Clinico Humanitas , Milan , Italy.
authors.forename: Pierina
authors.initials: P
authors.lastname: Navarria
authors.affiliation: a Radiation Oncology Department , Sacro Cuore Hospital , Negrar , Italy.
authors.forename: Niccolò
authors.initials: N
authors.lastname: Giaj Levra
authors.affiliation: a Radiation Oncology Department , Sacro Cuore Hospital , Negrar , Italy.
authors.forename: Rosario
authors.initials: R
authors.lastname: Mazzola
authors.affiliation: b Radiation Oncology Department , Istituto Clinico Humanitas , Milan , Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Scorsetti
mesh_terms: D001932:Brain Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000556:secondary; D006801:Humans; D010315:Particle Accelerators; D016634:Radiosurgery / Q000379:methods*
keywords: Brain metastases; Gamma Knife; Linac; radiotherapy approach; stereotactic radiosurgery