title: Influence of hemorheological factors on the development of retinal vein occlusion.
abstract: OBJECTIVE
  The aim of this article was to present the influence of hemorheological factors on appearance of Retinal Vein Occlusion (RVO). Article explains which factors predispose to the occurrence of RVO.
  
  
  METHODS
  Data presented in the article were collected from both review articles and research articles as well as other sources concerning hemorheology, pharmacology and ophthalmology.
  
  
  RESULTS
  Appearance of RVO is connected with blood viscosity and hemorheological parametres like aggregation of red blood cells, deformability of red blood cells, fibrinogen concentrations and haematocrit, and platelet activity. In the pathogenesis of retinal vein occlusion other risk factors were also indicated: age, systemic diseases and smoking. Such correlation has been indicated in numerous researches which were conducted over the last years. RVO is usually accompanied by macular oedema. RVO may successfully be treated using intravitreal dexamethasone implant.
  
  
  CONCLUSIONS
  Quick diagnosis and therapy create a possibility for successful treatment. Corticosteroid positive influence on visual acuity improvement has been indicted in two randomized, double-blind controlled studies - CRUISE and BRAVO. In both studies, the improvement of vision has been accompanied by a significant reduction of oedema in the vicinity of macula, reflected in the central retinal thickness.
authors.affiliation: Department of Ophthalmology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.|University Centre of Ophthalmology and Oncology, Independent Public Clinical Hospital, Medical University of Silesia, Katowice, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Michalska-Małecka
authors.affiliation: University Centre of Ophthalmology and Oncology, Independent Public Clinical Hospital, Medical University of Silesia, Katowice, Poland.
authors.forename: Dorota
authors.initials: D
authors.lastname: Śpiewak
authors.affiliation: Department of Biophysics, Faculty of Medicine in Zabrze, Medical University of Silesia, Zabrze, Poland.
authors.forename: Ludmiła
authors.initials: L
authors.lastname: Słowińska-Łożyńska
authors.affiliation: University Centre of Ophthalmology and Oncology, Independent Public Clinical Hospital, Medical University of Silesia, Katowice, Poland.
authors.forename: Justyna
authors.initials: J
authors.lastname: Sierocka-Stępień
mesh_terms: D001809:Blood Viscosity; D018056:Hemorheology; D006801:Humans; D008297:Male; D012170:Retinal Vein Occlusion / Q000097:blood*; D012307:Risk Factors; D013927:Thrombosis / Q000097:blood*
keywords: Hemorheology; blood viscosity; retinal vein occlusion; thrombosis