title: Acute Myeloid Leukemia in the Elderly Patient: New Strategies.
abstract: Although selected older adults with acute myeloid leukemia can benefit from intensive therapies, recent evidences support the use of lower-intensity therapies (hypomethylating agents or low-dose cytarabine) in most of these patients and emphasize the importance of tolerability and quality of life. Individualized approaches to treatment decision-making beyond consideration of chronologic age alone should therefore be considered. One promising strategy is to combine low-intensity treatments with novel agents.
authors.affiliation: Hematology Department, Hospices Civils de Lyon, Lyon-Sud Hospital, Bât.1G, Pierre-Bénite, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Thomas
keywords: Acute myeloid leukemia; Chemotherapy; Elderly; Hypomethylating agents; Supportive care; Targeted therapy