title: Cutaneous manifestations of breast cancer.
abstract: Breast cancer may present with cutaneous symptoms. The skin manifestations of breast cancer are varied. Some of the more common clinical presentations of metastatic cutaneous lesions from breast cancer will be described. Paraneoplastic cutaneous dermatoses have been reported as markers of breast malignancy and include erythema gyratum repens, acquired ichthyosis, dermatomyositis, multicentric reticulohistiocytosis, and hypertrichosis lanuginosa acquisita. Mammary Paget's disease, often associated with an underlying breast cancer, and Cowden syndrome, which has an increased risk of breast malignancy, each have specific dermatologic findings. Recognition of these distinct cutaneous signs is important in the investigation of either newly diagnosed or recurrent breast cancer.
authors.affiliation: Levine Cancer Institute, Carolinas HealthCare System, Charlotte, NC. Electronic address: Antoinette.Tan@CarolinasHealthcare.org.
authors.forename: Antoinette R
authors.initials: AR
authors.lastname: Tan
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology*; D003882:Dermatomyositis / Q000209:etiology; D004890:Erythema / Q000209:etiology; D005260:Female; D006801:Humans; D007057:Ichthyosis / Q000209:etiology; D010257:Paraneoplastic Syndromes / Q000209:etiology; D012878:Skin Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000556:secondary*
keywords: Breast cancer; Cowden syndrome; Cutaneous metastases; Dermatomyositis; Mammary Paget’s disease; Multicentric reticulohistiocytosis