title: Change in prognostic factors.
abstract: The purpose of evaluating prognostic factors in acute lymphoblastic leukemia is, first, to stratify patients into adverse- or good-risk groups, second, to determine different treatment options accordingly and, third, to evaluate their potential outcome. Prognostic factors are particularly relevant for disease-free survival and overall survival.
authors.affiliation: Department of Internal Medicine II, Hematology and Oncology, Goethe University Hospital , Frankfurt, Germany.
authors.forename: D
authors.initials: D
authors.lastname: Hoelzer
authors.affiliation: Department of Internal Medicine II, Hematology and Oncology, Goethe University Hospital , Frankfurt, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Gökbuget
keywords: acute lymphoblastic leukemia; minimal residual disease; prognostic factors; risk stratification; targeted therapies