title: Migraine: What Imaging Reveals.
abstract: Although migraine symptomatology is well-defined, our understanding of migraine pathophysiology is incomplete. Structural and functional brain imaging can contribute to a greater understanding of migraine pathophysiology. Recent neuroimaging studies demonstrate that migraine is associated with structural and functional alterations of brain regions commonly implicated in pain processing. This review summarizes recent brain structural and functional imaging findings in migraine and highlights those that are associated with characteristics such as the presence or absence of aura, associated cognitive dysfunction, sex-differences (male vs. female migraineurs), age, and disease burden.
authors.affiliation: Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA. Chong.Catherine@mayo.edu.
authors.forename: Catherine D
authors.initials: CD
authors.lastname: Chong
authors.affiliation: Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.
authors.forename: Todd J
authors.initials: TJ
authors.lastname: Schwedt
authors.affiliation: Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, AZ, 85054, USA.
authors.forename: David W
authors.initials: DW
authors.lastname: Dodick
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D001931:Brain Mapping / Q000379:methods*; D006801:Humans; D008881:Migraine Disorders / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D059906:Neuroimaging / Q000379:methods*
keywords: Functional connectivity; Functional magnetic resonance imaging; MRI; Magnetic resonance imaging; Migraine; Neuroimaging; Resting-state; fMRI