title: Changes in Corneal Thickness and Specular Microscopic Indices in Acute Unilateral Anterior Uveitis.
abstract: OBJECTIVE
  To compare central corneal thickness (CCT) and specular microscopic indices in active unilateral anterior uveitis with the same indices 1 week after the initiation of treatment.
  
  
  METHODS
  This study included 30 eyes with active unilateral idiopathic anterior uveitis. CCT and specular microscopic indices were compared before and after 1 week of the treatment with topical medications.
  
  
  RESULTS
  At the first visit, mean CCT was significantly greater in affected eyes (mean ± standard deviation: 514.0 ± 23.0) than in fellow eyes (493.2 ± 10.6) (p < 05). There was a significant decrease in CCT of the involved eye 1 week after start of treatment to 494.1 ± 23.1 μm (p < 05). No significant differences were observed in the specular microscopic indices between the affected and fellow eyes before treatment and 1 week after the treatment.
  
  
  CONCLUSIONS
  We found that eyes with unilateral active anterior uveitis had increased CCT in comparison to their healthy fellow eyes without a change in the specular microscopic indices.
authors.affiliation: a Department of Ophthalmology, Faculty of Medicine , Retina Research Center, Mashhad University of Medical Sciences, Mashhad , Iran.
authors.forename: Tooka
authors.initials: T
authors.lastname: Banaee
authors.affiliation: a Department of Ophthalmology, Faculty of Medicine , Retina Research Center, Mashhad University of Medical Sciences, Mashhad , Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Shafiee
authors.affiliation: a Department of Ophthalmology, Faculty of Medicine , Retina Research Center, Mashhad University of Medical Sciences, Mashhad , Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Alizadeh
authors.affiliation: a Department of Ophthalmology, Faculty of Medicine , Retina Research Center, Mashhad University of Medical Sciences, Mashhad , Iran.
authors.forename: Mohamad Hashem
authors.initials: MH
authors.lastname: Naseri
mesh_terms: D000208:Acute Disease; D000328:Adult; D001623:Betamethasone / Q000627:therapeutic use; D003315:Cornea / Q000473:pathology*; D003316:Corneal Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D004338:Drug Combinations; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008853:Microscopy; D008875:Middle Aged; D009883:Ophthalmic Solutions; D009929:Organ Size; D010276:Parasympatholytics / Q000627:therapeutic use; D014326:Tropanes / Q000627:therapeutic use; D014606:Uveitis, Anterior / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy; D055815:Young Adult
chemical_list: D004338:Drug Combinations; D005938:Glucocorticoids; D009883:Ophthalmic Solutions; D010276:Parasympatholytics; D014326:Tropanes; C100236:homatropine; D001623:Betamethasone
keywords: Anterior uveitis; central corneal thickness; specular microscopy