title: Arthroscopic anatomic double-bundle ACL reconstruction using irradiated versus non-irradiated hamstring tendon allograft.
abstract: OBJECTIVE
  To analyse the clinical outcome of anatomic double-bundle anterior cruciate ligament (ACL) reconstruction with irradiated versus non-irradiated hamstring allograft.
  
  
  METHODS
  One hundred and twelve patients who met the inclusion and exclusion criteria of the study were prospectively randomized consecutively into irradiated hamstring tendon allograft (Ir-Allo) group and non-irradiated allograft (Non-ir-Allo) group. All surgeries were done by the same senior surgeon with double-bundle reconstruction technique. Before surgery and at follow-up points, patients were evaluated by the same observer according to clinical evaluations.
  
  
  RESULTS
  Eighty-three patients (Non-ir-Allo, 44; Ir-Allo, 39) fulfilled complete follow-up and got full clinical evaluations. The mean follow-up period was 5.7 years (ranging from 5.0 to 6.5 years). At the final follow-up, significant differences were found when comparing the results of the two groups according to Lachman test, ADT, pivot shift test and KT-2000 arthrometer testing (P < 0.05). According to KT-2000, 86.4 % of patients in the Non-ir-Auto group and 35.9 % in the Ir-Allo group had a side-to-side difference of <3 mm. According to the overall IKDC, functional, subjective evaluations and activity level testing, no significant differences were found between the two groups. Regarding the arthritic progression, there was significant difference between the two groups (Ir-Allo group: 30.8 %, Non-ir-Allo group: 11.4 %, P < 0.05).
  
  
  CONCLUSIONS
  A significant increase in anterior and rotational laxity in patients of the Ir-Allo group was found according to evaluations. No significant differences in activity level and functional scores were found between the two groups. We do not advocate the irradiated hamstring tendon allograft for ACL reconstruction.
  
  
  METHODS
  I.
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China. shaoqi99@aliyun.com.
authors.forename: Shaoqi
authors.initials: S
authors.lastname: Tian
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China.
authors.forename: Chengzhi
authors.initials: C
authors.lastname: Ha
authors.affiliation: Department of Orthopaedics, Qingdao 3rd People's Hospital, Qingdao, 266000, Shandong, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China.
authors.forename: Yuanhe
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China.
authors.forename: Lun
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China.
authors.forename: Qicai
authors.initials: Q
authors.lastname: Li
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Orthopaedics, The Affiliated Hospital of Qingdao University, No. 1677 Wutaishan Road, Huangdao District, Qingdao, 266000, Shandong, China. sunkang_qy@aliyun.com.
authors.forename: Kang
authors.initials: K
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D064591:Allografts; D016118:Anterior Cruciate Ligament / Q000601:surgery; D000070598:Anterior Cruciate Ligament Injuries / Q000601:surgery*; D059549:Anterior Cruciate Ligament Reconstruction / Q000379:methods*; D001182:Arthroscopy / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005720:Gamma Rays / Q000627:therapeutic use*; D000070632:Hamstring Tendons / Q000637:transplantation*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D013242:Sterilization / Q000379:methods*; D014184:Transplantation, Homologous; D016896:Treatment Outcome; D055815:Young Adult
keywords: ACL; Anatomic reconstruction; Double-bundle; Hamstring tendon allograft; Irradiation; Prospective randomized study