title: Erythroid blast crisis in chronic myelogenous leukemia: Case report and review of literature.
abstract: Chronic myelogenous leukemia (CML) is a myeloproliferative disorder where over a period of time 15-20% of patients show blastic transformation with majority transforming into acute myeloid leukemia, most of which are of granulocytic lineage. Erythroid blast phase of CML is relatively rare with the incidence ranging from 0-10%. Further the incidence of acute erythroid leukemia by itself is fairly low amongst all acute leukemias. We report a case of 41-year-old patient with CML who failed to achieve cytogenetic remission, transformed to acute erythroid leukemia and eventually succumbed to the disease over a short period of time. Related literature is also reviewed.
authors.affiliation: Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, United States.
authors.forename: Rochelle Nagales
authors.initials: RN
authors.lastname: Nagamos
authors.affiliation: Department of Internal Medicine, Division of Hematology-Oncology, SUNY Upstate Medical University, Syracuse, NY, United States.
authors.forename: Teresa
authors.initials: T
authors.lastname: Gentile
authors.affiliation: Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, United States.
authors.forename: Neerja
authors.initials: N
authors.lastname: Vajpayee
keywords: Acute erythroid leukemia; Chronic myeloid leukemia