title: A Severe Case of Pigmentary Glaucoma in a Child With a Family History of Pigment Dispersion Syndrome.
abstract: To report a case of severe pigmentary glaucoma (PG) in a 13-year-old boy of a family affected by pigment dispersion syndrome (PDS).
  
  
  
  A 13-year-old child was referred to our hospital for severe bilateral glaucoma. A complete ophthalmologic evaluation including refraction, intraocular pressure, central corneal thickness, slit-lamp biomicroscopy, gonioscopy, fundus examination, and ultrasound biomicroscopy was performed. Family members were also examined and a family pedigree was obtained.
  
  
  
  Ophthalmologic examination revealed a severe bilateral PG with Krukenberg spindle and a widely open heavily pigmented iridocorneal angle. Ultrasound biomicroscopy showed a deep anterior chamber with pronounced iris concavity in both eyes. Within his family, his 15-year-old sister and 7-year-old brother were both affected by PDS diagnosed on gonioscopy findings.
  
  
  
  We report for the first time a severe case of pediatric PG with a family history of PDS. This case demonstrates that accurate screening is necessary in cases of familial PDS and PG, even in the pediatric population.
authors.affiliation: *Department of Ophthalmology III, Quinze-Vingts National Ophthalmology Hospital, DHU Sight Restore †Center for Clinical Investigations, Quinze-Vingts National Ophthalmology Hospital, INSERM-DHOS CIC 1423 ‡INSERM, U968 §Sorbonne Universités, UPMC University Paris 06, UMR_S 968, Institut de la Vision ∥CNRS, UMR_7210, Paris ¶Department of Ophthalmology, Ambroise Paré Hospital, APHP, University of Versailles Saint-Quentin-en-Yvelines, Versailles, France.
authors.forename: Vittoria
authors.initials: V
authors.lastname: Aragno
authors.forename: Pierre
authors.initials: P
authors.lastname: Zeboulon
authors.forename: Christophe
authors.initials: C
authors.lastname: Baudouin
authors.forename: Antoine
authors.initials: A
authors.lastname: Labbé
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D005260:Female; D020022:Genetic Predisposition to Disease; D005902:Glaucoma, Open-Angle / Q000150:complications / Q000175:diagnosis* / Q000209:etiology / Q000235:genetics; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D033401:Microscopy, Acoustic; D008875:Middle Aged; D010375:Pedigree; D012720:Severity of Illness Index; D014065:Tonometry, Ocular