title: [Prevalence of uterine anatomical anomalies in mexican women with recurrent pregnancy loss (RPL)].
abstract: BACKGROUND
  In Mexico, the information available about the prevalence of uterine anatomical anomalies as the direct and indirect cause of recurrent pregnancy loss (RPL) is limited.
  
  
  OBJECTIVE
  To know the prevalence and types of uterine anatomical anomalies in Mexican women with RPL.
  
  
  METHODS
  In a cross-sectional study, we included women attending a clinic for RPL from 2008 to 2013, with a history of three or more consecutive gestational losses, with the same couple and complete study protocol by factors. Altered anatomical factor was defined by any of the following diagnoses: Müllerian malformations, submucosal myomas, uterine synechiae, endometrial polyp, and cervical weakness, confirmed by laparoscopy and hysteroscopy.
  
  
  RESULTS
  We analyzed 188 women. The prevalence of anatomical anomalies was 41.5% (n = 78); the type of anatomical anomaly was: cervical weakness 15.9% (n = 30), septate uterus 11.7% (n = 22), and uterine synechiae 9.6% (n = 18), endometrial polyps 1.6% (n = 3), bicornuate uterus 1.1% (n = 2), arcuate uterus 0.5% (n = 1), didelphic uterus 0.5% (n=1), and submucosal myoma 0.5% (n=1). We identified the anatomic factor as the unique cause of RPL in 35.6% (n = 67) of cases.
  
  
  CONCLUSIONS
  The prevalence of altered anatomical factor in Mexican women with RPL is 41.5%; more frequent anomalies were: cervical weakness, septate uterus, and uterine synechiae.
authors.affiliation: Clínica de Pérdida Gestacional Recurrente, Departamento de Biología de la Reproducción, Instituto Nacional de Perinatología, Ciudad de México, México.
authors.forename: Fernando Antonio
authors.initials: FA
authors.lastname: Medrano-Uribe
authors.affiliation: Clínica de Pérdida Gestacional Recurrente, Departamento de Biología de la Reproducción, Instituto Nacional de Perinatología, Ciudad de México, México.
authors.forename: María Magdalena
authors.initials: MM
authors.lastname: Enríquez-Pérez
authors.affiliation: Clínica de Pérdida Gestacional Recurrente, Departamento de Biología de la Reproducción, Instituto Nacional de Perinatología, Ciudad de México, México.
authors.forename: Enrique
authors.initials: E
authors.lastname: Reyes-Muñoz
mesh_terms: D000026:Abortion, Habitual / Q000453:epidemiology*; D000293:Adolescent; D000328:Adult; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008800:Mexico; D011247:Pregnancy; D015995:Prevalence; D014564:Urogenital Abnormalities / Q000175:diagnosis / Q000453:epidemiology*; D014594:Uterine Neoplasms; D014599:Uterus / Q000002:abnormalities*; D055815:Young Adult