title: The human gut microbiota and its interactive connections to diet.
abstract: The microbiota of the gastrointestinal tract plays an important role in human health. In addition to their metabolic interactions with dietary constituents, gut bacteria may also be involved in more complex host interactions, such as modulation of the immune system. Furthermore, the composition of the gut microbiota may be important in reducing the risk of contracting particular gut infections. Changes in the microbiota during an individual's lifespan are accompanied by modifications in multiple health parameters, and such observations have prompted intense scientific efforts aiming to understand the complex interactions between the microbiota and its human host, as well as how this may be influenced by diet.
authors.affiliation: Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Milani
authors.affiliation: Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Ferrario
authors.affiliation: Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Turroni
authors.affiliation: Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Duranti
authors.affiliation: GenProbio Ltd, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Mangifesta
authors.affiliation: APC Microbiome Institute and School of Microbiology, National University of Ireland, Cork, Ireland.
authors.forename: D
authors.initials: D
authors.lastname: van Sinderen
authors.affiliation: Laboratory of Probiogenomics, Department of Life Sciences, University of Parma, Parma, Italy. marco.ventura@unipr.it.
authors.forename: M
authors.initials: M
authors.lastname: Ventura
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000209:etiology / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control; D001647:Bile Acids and Salts / Q000378:metabolism; D000072001:Diet, Healthy; D066273:Diet, Western / Q000009:adverse effects; D064806:Dysbiosis / Q000209:etiology / Q000276:immunology / Q000382:microbiology / Q000503:physiopathology; D005232:Fatty Acids, Volatile / Q000378:metabolism; D005285:Fermentation; D005767:Gastrointestinal Diseases / Q000209:etiology / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control; D000069196:Gastrointestinal Microbiome / Q000276:immunology / Q000502:physiology*; D006790:Host-Parasite Interactions; D006801:Humans; D006967:Hypersensitivity / Q000209:etiology / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control; D007113:Immunity, Innate; D008744:Methylamines / Q000378:metabolism; D009765:Obesity / Q000209:etiology / Q000276:immunology / Q000382:microbiology / Q000517:prevention & control
chemical_list: D001647:Bile Acids and Salts; D005232:Fatty Acids, Volatile; D008744:Methylamines; C005855:trimethyloxamine
keywords: diet; microbiota microbiome; prebiotics; probiotics