title: Predictive value of fetal hepatic biometry for birth weight and cord blood markers in gestational diabetes.
abstract: The objective of this study is to evaluate third-trimester fetal liver biometry, to predict birth weight and cord markers at birth in diabetic pregnancies.
  
  
  
  Fetal liver biometry (liver diameters, area and volume) was obtained between 32 and 34 weeks. A blood sample was obtained from cord after birth. Receiver operating characteristic (ROC) curve models were evaluated for 75th and 90th birth weight percentile. Univariate and multivariate models were used.
  
  
  
  All the hepatic diameters, area and sectional volume demonstrated significant differences in both birth weight percentile ⩾75 and ⩾90. All ROC curves showed significant values. A significant association was observed for all measurements with birth weight. In multivariate model, liver area volume gave significant values for predicting birth weight. Cord leptin, c-peptide and ferritin were related to fetal hepatic size.
  
  
  
  The hepatic changes in gestational diabetes were valid to predict birth weight and metabolic changes at birth.
authors.affiliation: High-Risk Pregnancy and Prenatal Diagnosis Unit, Obstetrics and Gynecology Department, Hospital Universitario Quiron Madrid, Pozuelo de Alarcon, Madrid, Spain.
authors.forename: J
authors.identifier: 0000-0003-1013-9914
authors.initials: J
authors.lastname: Garcia-Flores
authors.affiliation: High-Risk Pregnancy and Prenatal Diagnosis Unit, Obstetrics and Gynecology Department, Hospital Universitario Quiron Madrid, Pozuelo de Alarcon, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Cruceyra
authors.affiliation: High-Risk Pregnancy and Prenatal Diagnosis Unit, Obstetrics and Gynecology Department, Hospital Universitario Quiron Madrid, Pozuelo de Alarcon, Madrid, Spain.
authors.forename: M
authors.initials: M
authors.lastname: Cañamares
authors.affiliation: High-Risk Pregnancy and Prenatal Diagnosis Unit, Obstetrics and Gynecology Department, Hospital Universitario Quiron Madrid, Pozuelo de Alarcon, Madrid, Spain.
authors.forename: A
authors.initials: A
authors.lastname: Garicano
authors.affiliation: High-Risk Pregnancy and Prenatal Diagnosis Unit, Obstetrics and Gynecology Department, Hospital Universitario Quiron Madrid, Pozuelo de Alarcon, Madrid, Spain.
authors.forename: O
authors.initials: O
authors.lastname: Nieto
authors.affiliation: High-Risk Pregnancy and Prenatal Diagnosis Unit, Obstetrics and Gynecology Department, Hospital Universitario Quiron Madrid, Pozuelo de Alarcon, Madrid, Spain.
authors.forename: I
authors.initials: I
authors.lastname: Tamarit
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000032:analysis / Q000097:blood; D001699:Biometry / Q000379:methods; D001724:Birth Weight; D002096:C-Peptide / Q000032:analysis; D016640:Diabetes, Gestational / Q000453:epidemiology*; D005260:Female; D005312:Fetal Blood / Q000737:chemistry*; D020567:Fetal Weight; D005333:Fetus / Q000000981:diagnostic imaging*; D006801:Humans; D020738:Leptin / Q000032:analysis; D016014:Linear Models; D008099:Liver / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D015999:Multivariate Analysis; D009929:Organ Size; D011237:Predictive Value of Tests; D011247:Pregnancy; D011263:Pregnancy Trimester, Third; D011446:Prospective Studies; D012372:ROC Curve; D013030:Spain / Q000453:epidemiology; D016216:Ultrasonography, Prenatal
chemical_list: D015415:Biomarkers; D002096:C-Peptide; D020738:Leptin