title: All-Inside Versus Inside-Out Meniscal Repair With Concurrent Anterior Cruciate Ligament Reconstruction: A Meta-regression Analysis .
abstract: Meniscal tears are frequently repaired during anterior cruciate ligament reconstruction (ACLR).
  
  
  
  To systematically evaluate differences in clinical failures between all-inside and inside-out meniscal repairs performed during ACLR.
  
  
  
  Meta-analysis; Level of evidence, 4.
  
  
  
  A systematic review was perfomed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The databases queried included MEDLINE, CINAHL, EMBASE, and Cochrane Central Register of Controlled Trials. All English-language studies reporting failure rates after meniscal repair with either the all-inside or inside-out technique performed in conjunction with ACLR were identified between 1980 and 2015. Studies with a minimum 2-year follow-up were included. Reported outcomes, clinical meniscal repair failures, and complications were assessed. Studies were weighted according to the size of the clinical series and mean follow-up length. Inverse-variance-weighted mixed models were used to evaluate whether there was a significant difference in pooled reoperation rates between repair techniques.
  
  
  
  In total, 21 studies met inclusion criteria. Of these, 13 studies reported outcomes after all-inside repair, and 10 studies reported outcomes after inside-out repair (2 studies reported both). A total of 1126 patients were included in the analysis. The mean (±SD) follow-up for all-inside repair was 58.64 ± 22.24 months versus 76.25 ± 31.69 months for inside-out repair ( P = .13). The clinical failure rate for all-inside meniscal repair performed concurrently with ACLR was 16% (121/744) compared with 10% (39/382) for inside-out repair, and this was found to be significant ( P = .016). Implant irritation and device migration were the most common complications reported for all-inside repair; complication rates did not differ between the groups.
  
  
  
  There may be fewer early clinical failures when the inside-out technique is utilized for meniscal repair at the time of concomitant ACLR. Additional long-term studies will be useful to determine the operative success of these repairs over time.
authors.affiliation: University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Westermann
authors.affiliation: University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
authors.forename: Kyle R
authors.initials: KR
authors.lastname: Duchman
authors.affiliation: University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
authors.forename: Annunziato
authors.initials: A
authors.lastname: Amendola
authors.affiliation: University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
authors.forename: Natalie
authors.initials: N
authors.lastname: Glass
authors.affiliation: University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
authors.forename: Brian R
authors.initials: BR
authors.lastname: Wolf
mesh_terms: D016118:Anterior Cruciate Ligament / Q000601:surgery; D000070598:Anterior Cruciate Ligament Injuries / Q000601:surgery*; D059549:Anterior Cruciate Ligament Reconstruction / Q000379:methods*; D001182:Arthroscopy / Q000379:methods*; D006801:Humans; D008592:Menisci, Tibial / Q000601:surgery; D012044:Regression Analysis; D000070600:Tibial Meniscus Injuries / Q000601:surgery*
keywords: all-inside; anterior cruciate ligament; inside-out; knee; meniscal repair