title: Symptomatic Epidural Fluid Collection Following Cranioplasty after Decompressive Craniectomy for Traumatic Brain Injury.
abstract: OBJECTIVE
  Symptomatic epidural fluid collection (EFC) arising as a complication of cranioplasty is underestimated and poorly described. The purpose of this study was to investigate the risk factors for development of symptomatic EFC after cranioplasty following traumatic brain injury (TBI).
  
  
  METHODS
  From January 2010 to December 2014, 82 cranioplasties following decompressive hemicraniectomy for TBI were performed by a single surgeon. Of these 82 patients, 17 were excluded from this study due to complications including postoperative hematoma, hydrocephalus, or infection. Sixty-five patients were divided into 2 groups based on whether they had developed symptomatic EFC: 13 patients required an evacuation operation due to symptomatic EFC after cranioplasty (Group I), and 52 obtained good outcome without development of symptomatic EFC (Group II). We compared the 2 groups to identify the risk factors for symptomatic EFC according to sex, age, initial diagnosis, timing of cranioplasty, cerebrospinal fluid (CSF) leakage during cranioplasty, size of bone flap, and bone material.
  
  
  RESULTS
  A large bone flap and CSF leakage during cranioplasty were identified as the statistically significant risk factors (p<0.05) for development of symptomatic EFC. In Group I, 11 patients were treated successfully with 5 L catheter drainage, but 2 patients showed recurrent EFC, eventually necessitating bone flap removal.
  
  
  CONCLUSIONS
  A larger skull defect and intraoperative CSF leakage are proposed to be the significant risk factors for development of symptomatic EFC. Careful attention to avoid CSF leakage during cranioplasty is needed to minimize the occurrence of EFC, especially in cases featuring a large cranial defect.
authors.affiliation: Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.
authors.forename: Se Ho
authors.initials: SH
authors.lastname: Jeong
authors.affiliation: Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.
authors.forename: Ui Seok
authors.initials: US
authors.lastname: Wang
authors.affiliation: Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.
authors.forename: Seok Won
authors.initials: SW
authors.lastname: Kim
authors.affiliation: Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.
authors.forename: Sang Woo
authors.initials: SW
authors.lastname: Ha
authors.affiliation: Department of Neurosurgery, College of Medicine, Chosun University, Gwangju, Korea.
authors.forename: Jong Kyu
authors.initials: JK
authors.lastname: Kim
keywords: Complication; Cranioplasty; Decompressive craniectomy; Fluid, epidural