title: Influence of age and gender on the profile of exhaled volatile organic compounds analyzed by an electronic nose.
abstract: We aimed to investigate the effects of age and gender on the profile of exhaled volatile organic compounds. We evaluated 68 healthy adult never-smokers, comparing them by age and by gender. Exhaled breath samples were analyzed by an electronic nose (e-nose), resulting in "breathprints". Principal component analysis and canonical discriminant analysis showed that older subjects (≥ 50 years of age) could not be distinguished from younger subjects on the basis of their breathprints, as well as that the breathprints of males could not distinguished from those of females (cross-validated accuracy, 60.3% and 57.4%, respectively).Therefore, age and gender do not seem to affect the overall profile of exhaled volatile organic compounds measured by an e-nose.
authors.affiliation: Scuola di Medicina, Università degli Studi di Bari, Bari, Italia.
authors.forename: Silvano
authors.initials: S
authors.lastname: Dragonieri
authors.affiliation: Scuola di Medicina, Università degli Studi di Bari, Bari, Italia.
authors.forename: Vitaliano Nicola
authors.initials: VN
authors.lastname: Quaranta
authors.affiliation: Scuola di Medicina, Università degli Studi di Bari, Bari, Italia.
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Carratu
authors.affiliation: Scuola di Medicina, Università degli Studi di Bari, Bari, Italia.
authors.forename: Teresa
authors.initials: T
authors.lastname: Ranieri
authors.affiliation: Scuola di Medicina, Università degli Studi di Bari, Bari, Italia.
authors.forename: Onofrio
authors.initials: O
authors.lastname: Resta
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D000704:Analysis of Variance; D001944:Breath Tests / Q000379:methods; D003430:Cross-Sectional Studies; D062609:Electronic Nose; D045853:Exhalation; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D008297:Male; D008875:Middle Aged; D012016:Reference Values; D012737:Sex Factors; D013147:Spirometry; D055549:Volatile Organic Compounds / Q000032:analysis*; D055815:Young Adult
chemical_list: D055549:Volatile Organic Compounds