title: NCCN Guidelines Insights: Prostate Cancer Early Detection, Version 2.2016.
abstract: The NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Prostate Cancer Early Detection provide recommendations for prostate cancer screening in healthy men who have elected to participate in an early detection program. The NCCN Guidelines focus on minimizing unnecessary procedures and limiting the detection of indolent disease. These NCCN Guidelines Insights summarize the NCCN Prostate Cancer Early Detection Panel's most significant discussions for the 2016 guideline update, which included issues surrounding screening in high-risk populations (ie, African Americans, BRCA1/2 mutation carriers), approaches to refine patient selection for initial and repeat biopsies, and approaches to improve biopsy specificity.
authors.affiliation: UCSF Helen Diller Family Comprehensive Cancer Center
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authors.lastname: Carroll
authors.affiliation: UC San Diego Moores Cancer Center
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authors.affiliation: Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine
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authors.affiliation: The Ohio State University Comprehensive Cancer Center – James Cancer Hospital and Solove Research Institute
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authors.affiliation: Mayo Clinic Cancer Center
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authors.initials: DM
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authors.affiliation: The University of Texas MD Anderson Cancer Center
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authors.affiliation: The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
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authors.affiliation: Fred Hutchinson Cancer Research Center/Seattle Cancer Care Alliance
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authors.affiliation: Prostate Health Education Network
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authors.affiliation: Fred & Pamela Buffett Cancer Center at The Nebraska Medical Center
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authors.lastname: Hemstreet
authors.affiliation: City of Hope Comprehensive Cancer Center
authors.forename: Mark H
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authors.affiliation: Case Comprehensive Cancer Center/University Hospitals Seidman Cancer Center and Cleveland Clinic Taussig Cancer Institute
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authors.affiliation: University of Washington Medical Center/Seattle Cancer Care Alliance
authors.forename: Paul H
authors.initials: PH
authors.lastname: Lange
authors.affiliation: Dana-Farber/Brigham and Women’s Cancer Center
authors.forename: Kevin R
authors.initials: KR
authors.lastname: Loughlin
authors.affiliation: Huntsman Cancer Institute at the University of Utah
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authors.affiliation: University of Colorado Cancer Center
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authors.lastname: Maroni
authors.affiliation: Roswell Park Cancer Institute
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authors.lastname: Mohler
authors.affiliation: University of Michigan Comprehensive Cancer Center
authors.forename: Todd M
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authors.lastname: Morgan
authors.affiliation: Vanderbilt-Ingram Cancer Center
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authors.initials: KA
authors.lastname: Moses
authors.affiliation: Robert H. Lurie Comprehensive Cancer Center of Northwestern University
authors.forename: Robert B
authors.initials: RB
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authors.affiliation: Moffitt Cancer Center
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authors.affiliation: Duke Cancer Institute
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authors.initials: C
authors.lastname: Scales
authors.affiliation: University of Alabama at Birmingham Comprehensive Cancer Center
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authors.lastname: Shaneyfelt
authors.affiliation: Fox Chase Cancer Center
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authors.initials: MC
authors.lastname: Smaldone
authors.affiliation: Stanford Cancer Center
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authors.affiliation: Yale Cancer Center/Smilow Cancer Hospital
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authors.affiliation: Memorial Sloan Kettering Cancer Center
authors.forename: Andrew J
authors.initials: AJ
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authors.affiliation: St. Jude Children’s Research Hospital/The University of Tennessee Health Science Center
authors.forename: Robert
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authors.affiliation: National Comprehensive Cancer Network
authors.forename: Dorothy A
authors.initials: DA
authors.lastname: Shead
authors.affiliation: National Comprehensive Cancer Network
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authors.lastname: Freedman-Cass
mesh_terms: D055088:Early Detection of Cancer / Q000379:methods*; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000175:diagnosis*