title: Reversing adhesion with light: a general method for functionalized bead release from cells.
abstract: Coated beads retain great importance in the study of cell adhesion and intracellular communication; we present a generally applicable method permitting spatiotemporal control of bead adhesion from cells. Herein we demonstrate in vitro release of a poly-d-lysine (PDL) layer from anionic polystyrene beads, allowing complete bead release from rat cortical neurons post-adhesion.
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, H3A 2K6, Canada. christopher.barrett@mcgill.ca and Program in NeuroEngineering, McGill University, Montreal, H3A 2B4, Canada.
authors.forename: Alexis
authors.initials: A
authors.lastname: Goulet-Hanssens
authors.affiliation: Program in NeuroEngineering, McGill University, Montreal, H3A 2B4, Canada and ANANDA, Advanced Nano Design Applications, Montreal, H3H 2L3, Canada and Department of Physics, McGill University, Montreal, H3A 2T8, Canada.
authors.forename: Margaret H
authors.initials: MH
authors.lastname: Magdesian
authors.affiliation: Program in NeuroEngineering, McGill University, Montreal, H3A 2B4, Canada and Department of Physics, McGill University, Montreal, H3A 2T8, Canada.
authors.forename: G Monserratt
authors.initials: GM
authors.lastname: Lopez-Ayon
authors.affiliation: Program in NeuroEngineering, McGill University, Montreal, H3A 2B4, Canada and Department of Physics, McGill University, Montreal, H3A 2T8, Canada.
authors.forename: Peter
authors.initials: P
authors.lastname: Grutter
authors.affiliation: Department of Chemistry, McGill University, 801 Sherbrooke St. West, Montreal, H3A 2K6, Canada. christopher.barrett@mcgill.ca and Program in NeuroEngineering, McGill University, Montreal, H3A 2B4, Canada.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Barrett
mesh_terms: D000818:Animals; D002448:Cell Adhesion / Q000528:radiation effects*; D008027:Light; D008239:Lysine / Q000737:chemistry; D009474:Neurons / Q000737:chemistry / Q000378:metabolism; D011137:Polystyrenes / Q000737:chemistry*; D051381:Rats
chemical_list: D011137:Polystyrenes; D008239:Lysine