title: Synthesis of SF5CF2-Containing Enones and Instability of This Group in Specific Chemical Environments and Reaction Conditions.
abstract: The chemistry of the SF5CF2 moiety has been scarcely investigated. In this report, we present synthetic pathways to a variety of SF5CF2-substituted compounds starting from vinyl ethers and SF5CF2C(O)Cl. In specific chemical environments and under particular reaction conditions, the SF5CF2 moiety is unstable in downstream products resulting in the elimination of the SF5(-) anion and its decomposition to SF4 and F(-). Surprisingly, the formed F(-) can attack the intermediate difluorovinyl moiety to form trifluoromethyl substituted products. This appears to happen when an intermediate neighboring group participation involving a double bond is possible. Under slightly different conditions, the reaction stops at the stage of a difluorovinyl compound.
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster , Corrensstrasse 40, D-48149 Münster, Germany.|International Graduate School of Chemistry, University of Münster , Wilhelm-Klemm-Strasse 10, D-48149 Münster, Germany.
authors.forename: Piotr
authors.initials: P
authors.lastname: Dudziński
authors.affiliation: Department of Chemistry, Advanced Materials Research Laboratory, Clemson University , 91 Technology Drive, Anderson, South Carolina 29625, United States.
authors.forename: Andrej V
authors.initials: AV
authors.lastname: Matsnev
authors.affiliation: Department of Chemistry, Advanced Materials Research Laboratory, Clemson University , 91 Technology Drive, Anderson, South Carolina 29625, United States.
authors.forename: Joseph S
authors.initials: JS
authors.lastname: Thrasher
authors.affiliation: Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster , Corrensstrasse 40, D-48149 Münster, Germany.
authors.forename: Günter
authors.initials: G
authors.lastname: Haufe