title: High T Gives β Cells a Boost.
abstract: Androgen deficiency in men is associated with metabolic syndrome and diabetes, which has been attributed to actions of androgens upon insulin target tissues. In this issue of Cell Metabolism, Navarro et al. (2016) report a role for androgens and their receptor in the regulation of insulin secretion in β cells.
authors.affiliation: Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California San Diego, La Jolla, CA 92093-0695, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Wortham
authors.affiliation: Departments of Pediatrics and Cellular & Molecular Medicine, Pediatric Diabetes Research Center, University of California San Diego, La Jolla, CA 92093-0695, USA. Electronic address: masander@ucsd.edu.
authors.forename: Maike
authors.initials: M
authors.lastname: Sander
mesh_terms: D000818:Animals; D006801:Humans; D007328:Insulin / Q000378:metabolism; D050417:Insulin-Secreting Cells / Q000187:drug effects / Q000378:metabolism*; D008297:Male; D051379:Mice; D008954:Models, Biological; D011944:Receptors, Androgen / Q000378:metabolism; D011956:Receptors, Cell Surface / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D013739:Testosterone / Q000494:pharmacology*
chemical_list: D007328:Insulin; D011944:Receptors, Androgen; D011956:Receptors, Cell Surface; D013739:Testosterone