title: DjPiwiB: A Rich Nuclear Inheritance for Descendants of Planarian Stem Cells.
abstract: Stem cell differentiation involves a delicate balance of gene expression and transposon repression. In this issue of Developmental Cell, Shibata et al. (2016) show that a PIWI protein expressed in planarian stem cells is inherited by their differentiating descendants to ensure regenerative capacity of the flatworm via transposon silencing.
authors.affiliation: Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA; Department of Biology, Johns Hopkins University, Baltimore, MD 21218, USA.
authors.forename: Marla E
authors.initials: ME
authors.lastname: Tharp
authors.affiliation: Department of Embryology, Carnegie Institution for Science, Baltimore, MD 21218, USA. Electronic address: bortvin@ciwemb.edu.
authors.forename: Alex
authors.initials: A
authors.lastname: Bortvin
mesh_terms: D000818:Animals; D060565:Argonaute Proteins / Q000235:genetics / Q000378:metabolism*; D002454:Cell Differentiation; D002467:Cell Nucleus / Q000378:metabolism*; D020868:Gene Silencing; D040582:Inheritance Patterns / Q000235:genetics*; D008954:Models, Biological; D010932:Planarians / Q000166:cytology*; D013234:Stem Cells / Q000378:metabolism*
chemical_list: D060565:Argonaute Proteins