title: Enolate-mediated 1,3-dipolar cycloaddition reaction of β-functionalized ketones with nitrile oxides: direct access to 3,4,5-trisubstituted isoxazoles.
abstract: TMG-catalyzed [3 + 2] organocatalytic 1,3-dipolar cycloaddition reactions of β-functionalized ketones with nitrile oxides have been developed. This strategy could generate 3,4,5-trisubstituted isoxazoles in high yields and regioselectivities.
authors.affiliation: School of Pharmacy, Qingdao University, Qingdao, 266021, China. liwj@qdu.edu.cn.
authors.forename: Xiao
authors.initials: X
authors.lastname: Zhou
authors.forename: Xianhong
authors.initials: X
authors.lastname: Xu
authors.forename: Zhenyan
authors.initials: Z
authors.lastname: Shi
authors.forename: Kun
authors.initials: K
authors.lastname: Liu
authors.forename: Hua
authors.initials: H
authors.lastname: Gao
authors.forename: Wenjun
authors.initials: W
authors.lastname: Li