title: Biplane versus short-axis measures of the left atrium and ventricle in patients with systolic dysfunction assessed by magnetic resonance.
abstract: OBJECTIVE
  This study aims to investigate if the time saving biplane method can be an alternative to short-axis measurements for left atrium (LA) and left ventricle (LV) in cardiac magnetic resonance of patients with extensive LV remodeling.
  
  
  METHODS
  In 45 patients with coronary artery disease and systolic LV dysfunction [ejection fraction (EF)<50%], LA and LV end-diastolic volume, end-systolic volume, stroke volume, and EF were measured by the biplane area length and by the short-axis volume method.
  
  
  RESULTS
  No statistical differences between the biplane area length and short-axis volume were found for the LA end-systolic or the LV end-diastolic volumes. However, the biplane area length method overestimated LA stroke volume by 7.1±12.3 ml, LA EF by 6.7±8.8% (both P<.001), LV stroke volume by 6.2±12.9 ml (P=.002), and LV EF by 2.6±4.6% (P<.001). The differences in LV measurements were more evident in patients with severely distorted LV. For LA volume parameters, overall consistency between biplane area length and short-axis approach was good [all intraclass correlation coefficient (ICC)≥0.74] and for LV volume parameters, overall consistency between both approaches was excellent (all ICC≥0.93).
  
  
  CONCLUSIONS
  In patients with LV systolic dysfunction, the short-axis volume is superior to the biplane method and should be the first choice, when accurate determination of LA and LV EF is the main clinical indication for cardiac magnetic resonance.
authors.affiliation: Department of Radiology, Leiden University Medical Center, The Netherlands; University Institute of Cardiology, S.Orsola Hospital, Bologna, Italy. Electronic address: samuele.nanni@aosp.bo.it.
authors.forename: Samuele
authors.initials: S
authors.lastname: Nanni
authors.affiliation: Department of Radiology, Leiden University Medical Center, The Netherlands.
authors.forename: Jos J M
authors.initials: JJ
authors.lastname: Westenberg
authors.affiliation: Department of Cardiology, Leiden University Medical Center, The Netherlands.
authors.forename: Jeroen J
authors.initials: JJ
authors.lastname: Bax
authors.affiliation: Department of Cardiology, Leiden University Medical Center, The Netherlands.
authors.forename: Hans-Marc J
authors.initials: HM
authors.lastname: Siebelink
authors.affiliation: Department of Radiology, Leiden University Medical Center, The Netherlands.
authors.forename: Albert
authors.initials: A
authors.lastname: de Roos
authors.affiliation: Department of Radiology, Leiden University Medical Center, The Netherlands.
authors.forename: Lucia J M
authors.initials: LJ
authors.lastname: Kroft
mesh_terms: D000368:Aged; D002306:Cardiac Volume / Q000502:physiology*; D005260:Female; D006325:Heart Atria / Q000473:pathology* / Q000503:physiopathology; D006352:Heart Ventricles / Q000473:pathology* / Q000503:physiopathology; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D013318:Stroke Volume / Q000502:physiology*; D013599:Systole; D018487:Ventricular Dysfunction, Left / Q000175:diagnosis* / Q000503:physiopathology; D016277:Ventricular Function, Left / Q000502:physiology*
keywords: Coronary artery disease; Left atrium; Left ventricle; Magnetic resonance imaging; Ventricular function