title: Complications and oncologic outcomes following elective neck dissection with salvage laryngectomy for the N0 neck.
abstract: OBJECTIVE
  To investigate the difference in survival and complication outcomes between patients with a clinically and radiologically N0 neck who received an elective neck dissection at the time of salvage total laryngectomy compared to those who had salvage total laryngectomy alone.
  
  
  METHODS
  A retrospective chart review was performed on 125 salvage total laryngectomy patients who were clinically and radiologically N0 preoperatively. Performance of an elective neck dissection and other factors were tested for associations with various postoperative complications, disease-free survival, and overall survival.
  
  
  RESULTS
  Ninety-eight patients underwent elective neck dissection, of which ten had positive nodal pathology. Elective neck dissection was not significantly associated with complications or survival outcomes. Positive nodal disease was associated with worse disease-free and overall survival on multivariate analysis.
  
  
  CONCLUSIONS
  In patients with clinically and radiologically N0 necks undergoing salvage total laryngectomy, an elective neck dissection can provide prognostic information but does not appear to be significantly associated with increased complications or improved survival.
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 650D, Miami, FL. Electronic address: freiserme@upmc.edu.
authors.forename: Monika E
authors.initials: ME
authors.lastname: Freiser
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 650D, Miami, FL. Electronic address: rojo@earsinus.com.
authors.forename: Rosemary B
authors.initials: RB
authors.lastname: Ojo
authors.affiliation: Biostatistics Collaboration and Consulting Core, Division of Biostatistics, Department of Public Health Sciences, University of Miami Miller School of Medicine, 1120 N.W. 14th Street, Suite 1049, Miami, FL. Electronic address: Klo@biostat.med.miami.edu.
authors.forename: Kaming
authors.initials: K
authors.lastname: Lo
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 650D, Miami, FL. Electronic address: Sandra.saintvictor@jhsmiami.org.
authors.forename: Sandra
authors.initials: S
authors.lastname: Saint-Victor
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 650D, Miami, FL. Electronic address: bolligc@health.missouri.edu.
authors.forename: Craig
authors.initials: C
authors.lastname: Bollig
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 650D, Miami, FL. Electronic address: CNayak@med.miami.edu.
authors.forename: Chetan S
authors.initials: CS
authors.lastname: Nayak
authors.affiliation: Department of Otolaryngology, University of Miami Miller School of Medicine, 1120 NW 14th Street, Suite 650D, Miami, FL. Electronic address: zsargi@med.miami.edu.
authors.forename: Zoukaa B
authors.initials: ZB
authors.lastname: Sargi
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D007822:Laryngeal Neoplasms / Q000401:mortality / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection; D009367:Neoplasm Staging; D011183:Postoperative Complications / Q000453:epidemiology*; D012189:Retrospective Studies; D016879:Salvage Therapy; D015996:Survival Rate; D016896:Treatment Outcome