title: The Plant Mitochondrial Transportome: Balancing Metabolic Demands with Energetic Constraints.
abstract: In plants, mitochondrial function is associated with hundreds of metabolic reactions. To facilitate these reactions, charged substrates and cofactors move across the charge-impermeable inner mitochondrial membrane via specialized transporters and must work cooperatively with the electrochemical gradient which is essential for mitochondrial function. The regulatory framework for mitochondrial metabolite transport is expected to be more complex in plants than in mammals owing to the close metabolic association between mitochondrial, plastids, and peroxisome metabolism, as well as to the major diurnal fluctuations in plant metabolic function. We propose here how recent advances can be integrated towards defining the mitochondrial transportome in plants. We also discuss what this reveals about sustaining cooperativity between bioenergetics, metabolism, and transport in typical and challenging environments.
authors.affiliation: Australian Reseach Council (ARC) Centre of Excellence in Plant Energy Biology, The University of Western Australia, 35 Stirling Highway, Crawley 6009, Australia.
authors.forename: Chun Pong
authors.initials: CP
authors.lastname: Lee
authors.affiliation: Australian Reseach Council (ARC) Centre of Excellence in Plant Energy Biology, The University of Western Australia, 35 Stirling Highway, Crawley 6009, Australia. Electronic address: harvey.millar@uwa.edu.au.
authors.forename: A Harvey
authors.initials: AH
authors.lastname: Millar
mesh_terms: D001692:Biological Transport / Q000235:genetics / Q000502:physiology; D006706:Homeostasis / Q000235:genetics / Q000502:physiology; D008928:Mitochondria / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000235:genetics / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D017382:Reactive Oxygen Species
keywords: bioenergetics; metabolism; mitochondria; reactive oxygen species; respiration; transport