title: [Effect of metabolic uncontrolled diabetes mellitus (DM) on the resistance index of renal (IR) Interlobar arteries assessed with pulsed Doppler].
abstract: BACKGROUND
  Diabetes mellitus is a chronic degenerative disease characterized by elevated hyperglycemia, triggering a series of processes and culminating in chronic, uncontrolled, cellular and vascular damage in different organs.
  
  
  OBJECTIVE
  To assess whether the elevated glycosylated hemoglobin, microalbuminuria, and the time evolution of more than 10 years of diabetes mellitus are associated with elevated resistance index of the interlobar renal arteries assessed with pulsed Doppler in patients with metabolic uncontrolled diabetes mellitus.
  
  
  METHODS
  Transversal-analytical, observational, prospective study that included diabetic patients attending UMAE abdominal ultrasound in 25 of IMSS, from October 15, 2014 to November 15, 2014, which was performed for pulsed Doppler index resistance of vascular interlobar renal arteries and was collected from electronic medical records: age, sex, glycated hemoglobin, and microalbuminuria. The association between metabolic uncontrolled diabetes mellitus was analyzed with the elevation of resistance index by χ(2) test or Fisher, being significant with a value of p < 0.05, and to assess the magnitude of the association that was measured with a response magnitude of 95%.
  
  
  RESULTS
  63 patients with type 2 diabetes were examined, with an average age of 52.3 ± 14.2 years, 41 were older than 50 years (65.0%), 26 with hypertension (41.2%), 32 with higher levels of glycated hemoglobin 7 (50.8%), 35 with normoalbuminuria (55.6%), 28 with microalbuminuria (44.4%), and 39 with a time evolution of diabetes of more than 10 years (61.9%). We observed a statistically significant difference between microalbuminuria and increased duration of diabetes mellitus with high resistance index.
  
  
  CONCLUSIONS
  The alterations in renal microvasculature conditioned by the occurrence of microalbuminuria in diabetic nephropathy and the duration of diabetes are strongly associated with higher resistance index.
authors.affiliation: Departamento de Radiología e Imagen, UMAE N.o 25, IMSS, Monterrey, N.L., México.
authors.forename: Luis Cesar
authors.initials: LC
authors.lastname: Muraira-Cárdenas
authors.affiliation: Departamento de Radiología e Imagen, UMAE N.o 25, IMSS, Monterrey, N.L., México.
authors.forename: Martín
authors.initials: M
authors.lastname: Barrios-Pérez
mesh_terms: D000328:Adult; D000368:Aged; D000419:Albuminuria / Q000378:metabolism / Q000503:physiopathology; D001158:Arteries / Q000000981:diagnostic imaging; D003430:Cross-Sectional Studies; D003920:Diabetes Mellitus / Q000378:metabolism* / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007668:Kidney / Q000098:blood supply* / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D018617:Ultrasonography, Doppler, Pulsed; D014655:Vascular Resistance