title: Platelet function testing: from routine to specialist testing.
abstract: Platelets have many functions within the haemostatic system, and when these actions are diminished for whatever reason, a bleeding tendency can manifest. Unravelling the reason(s) for this bleeding can be complex due to the multiple roles platelets perform. This review seeks to explain each level of platelet testing moving from those performed at local hospital laboratories to those performed by specialist centres and university research departments. It will examine the testing available and discuss when to move on to additional testing.
authors.affiliation: a Department of Haematology , University Hospital Bristol , Bristol , UK.
authors.forename: David
authors.initials: D
authors.lastname: Gurney
mesh_terms: D000046:Academic Medical Centers; D015415:Biomarkers / Q000097:blood; D001791:Blood Platelet Disorders / Q000097:blood / Q000175:diagnosis* / Q000235:genetics; D001792:Blood Platelets / Q000378:metabolism / Q000473:pathology; D019411:Clinical Laboratory Techniques; D019091:Critical Pathways; D005820:Genetic Testing; D006470:Hemorrhage / Q000097:blood / Q000175:diagnosis* / Q000235:genetics; D006801:Humans; D010974:Platelet Aggregation; D010979:Platelet Function Tests / Q000379:methods*; D011237:Predictive Value of Tests; D013038:Specialization; D057188:Workflow
chemical_list: D015415:Biomarkers
keywords: Platelet; aggregation; analysis; analytical techniques; function