title: Multistage ozone and biological treatment system for real wastewater containing antibiotics.
abstract: In this study, a multistage treatment system was proposed to treat real pharmaceutical wastewater containing the antibiotic amoxicillin. Ozonation (O3), and ozonation combined with aerobic biodegradation, were performed. The real pharmaceutical wastewater presented a high concentration of organic matter (TOC: 803 mg C·L-1and COD: 2775 mg O2·L-1), significant amoxicillin content (50 mg L-1) and acute ecotoxicity (Aliivibrio fischeri aTU: 48.22). Ozonation proved to be effective for amoxicillin degradation (up to 99%) and the results also indicated the removal of the original colour of the wastewater, with average consumption of 1 g of ozone. However, the ozonation system alone could not achieve complete mineralization. Therefore, a combination of ozonation and biodegradation in a multistage system was proposed in order to improve cost and treatment efficiency. The multistage treatment system presented promising results, achieving degradation of more than 99% of the amoxicillin, more than 98% of the original chemical oxygen demand (COD), and 90% of initial toxicity, with the consumption of approximately 500 mg of ozone. This indicates that this system could prevent dangerous and biorecalcitrant antibiotics from entering water resources.
authors.affiliation: Universidade Federal de Minas Gerais - UFMG, Department of Sanitary and Environmental Engineering, Av. Antônio Carlos nº 6627 Bairro Pampulha, Belo Horizonte, Brazil.
authors.forename: Rafaela B P
authors.initials: RBP
authors.lastname: Marcelino
authors.affiliation: Universidade Federal de Minas Gerais - UFMG, Department of Sanitary and Environmental Engineering, Av. Antônio Carlos nº 6627 Bairro Pampulha, Belo Horizonte, Brazil.
authors.forename: Mônica M D
authors.initials: MMD
authors.lastname: Leão
authors.affiliation: Universidade Federal de Minas Gerais - UFMG, Chemistry Department, Av. Antônio Carlos nº 6627 Bairro Pampulha, Belo Horizonte, Brazil.
authors.forename: Rochel M
authors.initials: RM
authors.lastname: Lago
authors.affiliation: Universidade Federal de Minas Gerais - UFMG, Department of Sanitary and Environmental Engineering, Av. Antônio Carlos nº 6627 Bairro Pampulha, Belo Horizonte, Brazil. Electronic address: camila@desa.ufmg.br.
authors.forename: Camila C
authors.initials: CC
authors.lastname: Amorim
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry; D001673:Biodegradation, Environmental; D010126:Ozone / Q000737:chemistry*; D014865:Waste Disposal, Fluid; D062065:Wastewater / Q000737:chemistry*; D014874:Water Pollutants, Chemical / Q000737:chemistry; D018508:Water Purification
chemical_list: D000900:Anti-Bacterial Agents; D010126:Ozone; D062065:Wastewater; D014874:Water Pollutants, Chemical
keywords: Aerobic biological treatment; Amoxicillin; Multistage treatment system; Ozonation; Pharmaceutical wastewater