title: [Zika virus infection or the future of infectious diseases].
abstract: Zika virus belongs to the Flaviridae, an extended phylogenetic family containing dengue or yellow fever, viruses whose shared main vector are Aedes aegypti mosquitoes. The virus originally came from Central African simian reservoirs and, from there, expanded rapidly across the Pacific to South America. The disease is an example of exantematic fever usually mild. Mortality is very low and mainly limited to secondary Guillain-Barré or fetal microcephaly cases. Diagnostic confirmation requires a RT-PCR in blood up to the 5th day from the onset or in urine up to the 10-14th day. Specific IgM are identifiable from the 5th symptomatic day. Clinically, a suspected case should comply with: a) a journey to epidemic areas; b) a clinically compatible appearance with fever and skin rash, and c) a generally normal blood count/basic biochemistry. There is some evidence that causally relates Zika virus infection with fetal microcephaly. While waiting for definitive data, all pregnant women coming from Central or South America should be tested for Zika virus.
authors.affiliation: PROSICS Metropolitana Nord, Institut Català de la Salut, Universitat Autònoma de Barcelona, Santa Coloma de Gramenet, España. Electronic address: lvalerio.bnm.ics@gencat.cat.
authors.forename: Lluís
authors.initials: L
authors.lastname: Valerio Sallent
authors.affiliation: PROSICS Metropolitana Nord, Unidad de Enfermedades Infecciosas, Servicio de Medicina Interna, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Institut Català de la Salut, Badalona, Barcelona, España.
authors.forename: Sílvia
authors.initials: S
authors.lastname: Roure Díez
authors.affiliation: Servicio de Microbiología, Hospital Universitari Germans Trias i Pujol Universitat Autònoma de Barcelona, Institut Català de la Salut, Badalona, Barcelona, España.
authors.forename: Gema
authors.initials: G
authors.lastname: Fernández Rivas
mesh_terms: D000330:Aedes / Q000821:virology; D000818:Animals; D004197:Disease Reservoirs; D004199:Disease Vectors; D014943:Global Health; D006801:Humans; D010802:Phylogeny; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification; D000071243:Zika Virus Infection / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission / Q000821:virology
keywords: Aedes albopictus; Europa; Europe; Zika