title: One pot preparation of silver nanoparticles decorated TiO2 mesoporous microspheres with enhanced antibacterial activity.
abstract: We report a simple "one-pot" solvothermal preparation of silver nanoparticles (Ag NPs) decorated mesoporous titania (TiO2) microspheres as an effective antibacterial agent. TBOT as Ti source was hydrolyzed and crystallized in media composed of acetic acid and ethanol, in which esterification catalyzed by TBOT occurred for in-situ "controlled water release". AgNO3 as Ag source was reduced by ethanol to form Ag NPs embedded in the TiO2 microspheres. The effect of AgNO3 and HAc on the morphology of Ag/TiO2 was investigated. The Ag/TiO2 with various Ag content showed excellent antibacterial activities with extremely low minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against Escherichia coli and Staphylococcus aureus when compared with colloidal Ag NPs.
authors.affiliation: Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
authors.forename: Yuemei
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. Electronic address: ymdeng@szu.edu.cn.
authors.forename: Yuanming
authors.initials: Y
authors.lastname: Deng
authors.affiliation: College of Chemistry and Chemical Engineering, Shenzhen University, Shenzhen 518060, China.
authors.forename: Yitao
authors.initials: Y
authors.lastname: Pu
authors.affiliation: Newnham College, Sidgwick Avenue, Cambridge CB3 9DF, United Kingdom.
authors.forename: Bijun
authors.initials: B
authors.lastname: Tang
authors.affiliation: Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
authors.forename: Yikun
authors.initials: Y
authors.lastname: Su
authors.affiliation: Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. Electronic address: tjn@szu.edu.cn.
authors.forename: Jiaoning
authors.initials: J
authors.lastname: Tang
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D053768:Metal Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D008826:Microbial Sensitivity Tests; D008855:Microscopy, Electron, Scanning; D008863:Microspheres; D016062:Porosity; D012834:Silver / Q000737:chemistry*; D012835:Silver Nitrate / Q000737:chemistry; D013211:Staphylococcus aureus / Q000187:drug effects; D014025:Titanium / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; C009495:titanium dioxide; D012834:Silver; D012835:Silver Nitrate; D014025:Titanium
keywords: Antibacterial; Mesoporous; Silver nanoparticles; Solvothermal; Titania microspheres