title: How can we target oxidative stress in the treatment of neurodegenerative diseases?
authors.affiliation: Department of Pharmacological & Pharmaceutical Sciences, Center for Experimental Therapeutics & PharmacoInformatics, University of Houston College of Pharmacy, Houston, TX 77204-5037, USA.
authors.forename: Hironari
authors.initials: H
authors.lastname: Akasaka
authors.affiliation: Department of Pharmacological & Pharmaceutical Sciences, Center for Experimental Therapeutics & PharmacoInformatics, University of Houston College of Pharmacy, Houston, TX 77204-5037, USA.
authors.forename: Ke-He
authors.initials: KH
authors.lastname: Ruan
mesh_terms: D000975:Antioxidants / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D008928:Mitochondria / Q000187:drug effects / Q000378:metabolism; D019636:Neurodegenerative Diseases / Q000188:drug therapy* / Q000378:metabolism / Q000473:pathology; D009942:Organometallic Compounds / Q000737:chemistry / Q000494:pharmacology*; D018384:Oxidative Stress / Q000187:drug effects*; D015125:Oxyquinoline / Q000737:chemistry / Q000494:pharmacology*; D017382:Reactive Oxygen Species / Q000378:metabolism
chemical_list: D000975:Antioxidants; D009942:Organometallic Compounds; D017382:Reactive Oxygen Species; D015125:Oxyquinoline
keywords: lipid oxidation; mitochondria; neurodegenerative diseases; oxidative stress; reactive oxygen species; redox-active metal ions