title: Molecular Detection and Phylogenetic Characteristics of Herpesviruses in Rectal Swab Samples from Rodents and Shrews in Southern China.
abstract: Herpesviruses (HVs) can cause asymptomatic, benign, or fatal infections in a variety of animal species. However, the prevalence and phylogenetic characteristics of HVs in rodents and shrews in China are poorly understood. We thus performed a molecular detection and phylogenetic analysis of rat and shrew HVs in southern China between 2012 and 2014. Seventeen (6.7%) of 255 rectal swab specimens from rats and six (6.7%) of 90 rectal swab specimens from shrews tested positive for HVs. Phylogenetic analysis revealed that rodent and shrew HVs detected in this study were species specific, clustering in the Betaherpesvirinae and Gammaherpesvirinae clade. Novel Macavirus was detected in Rattus norvegicus (RN/13YX52/24 and RN/14HC50) and gammaherpesviruses in Suncus murinus (SM/14BY7/16/20/97/99/106).These findings have contributed to our understanding of the taxonomy, phylogeny, and biology of HVs.
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Xue-Yan
authors.initials: XY
authors.lastname: Zheng
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Min
authors.initials: M
authors.lastname: Qiu
authors.affiliation: 2 Xiamen Center for Disease Control and Prevention , Xiamen, China .
authors.forename: Xue-Mei
authors.initials: XM
authors.lastname: Ke
authors.affiliation: 3 Guangzhou Yuexiu Center for Disease Control and Prevention , Guangzhou, Guangdong, China .
authors.forename: Wen
authors.initials: W
authors.lastname: Zhou
authors.affiliation: 4 State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical University , Guangzhou, China .
authors.forename: Wei-Jie
authors.initials: WJ
authors.lastname: Guan
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Shao-Wei
authors.initials: SW
authors.lastname: Chen
authors.affiliation: 5 Department of Bioinformatics, School of Basic Medical Sciences, Southern Medical University , Guangzhou, China .
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Li
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Shu-Ting
authors.initials: ST
authors.lastname: Huo
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Hui-Fang
authors.initials: HF
authors.lastname: Chen
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Jiang
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Xue-Shan
authors.initials: XS
authors.lastname: Zhong
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Yi-Quan
authors.initials: YQ
authors.lastname: Xiong
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Shu-Juan
authors.initials: SJ
authors.lastname: Ma
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Jing
authors.initials: J
authors.lastname: Ge
authors.affiliation: 1 Department of Epidemiology, Guangdong Provincial Key Laboratory of Tropical Disease Research, School of Public Health and Tropical Medicine, Southern Medical University , Guangzhou, Guangdong, China .
authors.forename: Qing
authors.initials: Q
authors.lastname: Chen
mesh_terms: D000818:Animals; D000835:Animals, Wild; D002681:China / Q000453:epidemiology; D006564:Herpesviridae / Q000235:genetics* / Q000302:isolation & purification*; D006566:Herpesviridae Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology; D010802:Phylogeny; D012007:Rectum / Q000821:virology; D012376:Rodent Diseases / Q000453:epidemiology / Q000821:virology*; D012377:Rodentia / Q000821:virology*; D012788:Shrews / Q000821:virology*
keywords: Herpesvirus; Phylogeny; Rodent; Shrew; Southern China.