title: Importance and usage of the CHA2DS2-VASc score in predicting acute stent thrombosis.
abstract: OBJECTIVE
  The CHA2DS2-VASc score is used to estimate thromboembolic risk in atrial fibrillation (AF). Its usefulness in predicting outcome in patients after a percutaneous coronary intervention is unknown. We aimed to evaluate the predictive value of the CHA2DS2-VASc score in AF-free patients who have undergone stent implantation.
  
  
  METHODS
  Patients were evaluated retrospectively. Among the 1371 patients, 38 presented with acute stent thrombosis (ST) and were included in the study. The CHA2DS2-VASc score was calculated before percutaneous coronary intervention and the association between the score and stent thrombosis was investigated.
  
  
  RESULTS
  The patients were grouped into ST (+) and ST (-). The average CHA2DS2-VASc score for the ST (+) group was 3.79, whereas that for the ST (-) group was 2.16 (P<0.001). A direct correlation was observed between CHA2DS2-VASc scores and the rate of ST. When patients with a CHA2DS2-VASc score of greater than 2 were compared with those with a CHA2DS2-VASc score of up to 2, the higher score had a higher frequency of ST (P<0.001) and multivariate analysis identified the CHA2DS2-VASc score as an independent predictor of acute ST.
  
  
  CONCLUSIONS
  A CHA2DS2-VASc score of greater than 2 was found to be an independent predictor for incidence of ST. The role of the CHA2DS2-VASc score in predicting ST has not been investigated earlier in an AF-free population and our study is the first to explore this aspect.
authors.affiliation: Department of Cardiology, Turkey Yüksek İhtisas Education and Research Hospital, Ankara, Turkey.
authors.forename: Sefa
authors.initials: S
authors.lastname: Ünal
authors.forename: Burak
authors.initials: B
authors.lastname: Açar
authors.forename: Çağri
authors.initials: Ç
authors.lastname: Yayla
authors.forename: Mustafa Mücahit
authors.initials: MM
authors.lastname: Balci
authors.forename: Ahmet
authors.initials: A
authors.lastname: Ertem
authors.forename: Meryem
authors.initials: M
authors.lastname: Kara
authors.forename: Orhan
authors.initials: O
authors.lastname: Maden
authors.forename: Şenay Funda
authors.initials: ŞF
authors.lastname: Dereağzi
mesh_terms: D000368:Aged; D016009:Chi-Square Distribution; D003324:Coronary Artery Disease / Q000175:diagnosis / Q000628:therapy*; D003328:Coronary Thrombosis / Q000175:diagnosis / Q000209:etiology*; D003661:Decision Support Techniques; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D062645:Percutaneous Coronary Intervention / Q000009:adverse effects* / Q000295:instrumentation*; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D015607:Stents; D016896:Treatment Outcome