title: A New Iridoid from the Aerial Parts of Hedyotis pilulifera.
abstract: A new iridoid, 10-acetylborreriagenin (1), and five known iridoid glycosides (2-6), were isolated from the aerial parts of Hedyotis pilulifera. Their structures were elucidated by spectral analyses, including 1D- and 2D-NMR, and HR-ESI-MS, and comparisons with the NMR data reported in the literature. The isolated compounds 1-6 were tested against six bacterial species. Among them, 10-acetylborreriagenin (1) showed antibacterial activity against Staphylococcus aureus, with an MIC value of 100 µg/mL.
authors.forename: Nguyen Thi
authors.initials: NT
authors.lastname: Hoai
authors.forename: Ho Viet
authors.initials: HV
authors.lastname: Duc
authors.forename: Nguyen Dinh Quynh
authors.initials: ND
authors.lastname: Phu
authors.forename: Takeshi
authors.initials: T
authors.lastname: Kodama
authors.forename: Takuya
authors.initials: T
authors.lastname: Itob
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Morita
mesh_terms: D039823:Iridoids / Q000737:chemistry*; D015394:Molecular Structure; D035261:Plant Components, Aerial / Q000737:chemistry*; D019666:Rubiaceae / Q000737:chemistry*
chemical_list: C000608391:10-acetylborreriagenin; D039823:Iridoids