title: Late dissemination via cerebrospinal fluid of papillary tumor of the pineal region: a case report and literature review.
abstract: Papillary tumor of the pineal region (PTPR) represents a recently described entity and was included in the 2007 World Health Organization (WHO) classification of central nervous system tumors. The biological and clinical behavior of PTPR is variable and may correspond to WHO grades II or III. Papillary tumor of the pineal region can show aggressive biological behavior with local relapses and dissemination via the cerebrospinal fluid. Several cases of PTPR with leptomeningeal seeding and multiple lesions or spinal metastasis have been reported. We present an unusual clinical history of papillary tumor of the pineal region with ventricular and spinal dissemination five years after primary surgical treatment.
authors.affiliation: Elżbieta Nowicka, 3rd Radiotherapy and Chemotherapy Department, Maria Sklodowska-Curie Memorial Cancer Center and Institute of Oncology, Gliwice Branch, 16 Wybrzeże Armii Krajowej St., 44-100 Gliwice, Poland, e-mail: enowicka@io.gliwice.pl.
authors.forename: E
authors.initials: E
authors.lastname: Nowicka
authors.forename: B
authors.initials: B
authors.lastname: Bobek-Billewicz
authors.forename: J
authors.initials: J
authors.lastname: Szymaś
authors.forename: R
authors.initials: R
authors.lastname: Tarnawski
mesh_terms: D001932:Brain Neoplasms / Q000134:cerebrospinal fluid / Q000473:pathology*; D002291:Carcinoma, Papillary / Q000134:cerebrospinal fluid* / Q000473:pathology; D006801:Humans; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D010870:Pineal Gland / Q000473:pathology*; D010871:Pinealoma / Q000473:pathology*