title: [The age and sex frequencies of patients with leukemia seen in two reference centers in the metropolitan area of Mexico City].
abstract: BACKGROUND
  A lack of a population-based cancer registry or underreporting is common in developing countries, without knowledge of the true dimensions of the problem.
  
  
  OBJECTIVE
  To describe the age and sex frequencies of the major subtypes of leukemias in two reference hospitals in the metropolitan area of Mexico City.
  
  
  METHODS
  A descriptive and retrospective study, based on medical records of two hematology services during January 2007 to October 2014; all cases diagnosed with leukemia were included.
  
  
  RESULTS
  A total of 1,432 cases were included, with a median age of 38 years old (2 months to 115 years). There were significant age differences between subtypes of leukemia (ANOVA test, p = 0.000); chronic lymphocytic with a mean age of 64.8 years, higher than chronic myeloid (43.4 years) and all acute leukemias (lymphoblastic: 32.6 years, myeloblastic 43.5 years). Of the patients, 51.8% (n = 742) were women, although males predominated in chronic myeloid (57.8%) and lymphocytic (60%) leukemia. Acute lymphoblastic leukemia was the more common variety, L2 subtype of the French-American-British classification, followed by myeloid leukemia M4, M2, and chronic myeloid.
  
  
  CONCLUSIONS
  it is necessary to develop inter-institutional works in order to group data of different population sectors and improve the epidemiological profile of leukemias in Mexico.
authors.affiliation: Unidad de Medicina Experimental, Facultad de Medicina, UNAM, Ciudad de México, México.
authors.forename: Adrián
authors.initials: A
authors.lastname: Santoyo-Sánchez
authors.affiliation: Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México.
authors.forename: Christian Omar
authors.initials: CO
authors.lastname: Ramos-Peñafiel
authors.affiliation: Área de Hematología, Hospital de Alta Especialidad Bicentenario de la República, ISSSTE, Ciudad de México, México.
authors.forename: Azucena
authors.initials: A
authors.lastname: Saavedra-González
authors.affiliation: Área de Hematología, Hospital de Alta Especialidad Bicentenario de la República, ISSSTE, Ciudad de México, México.
authors.forename: Lizbeth
authors.initials: L
authors.lastname: González-Almanza
authors.affiliation: Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México.
authors.forename: Adolfo
authors.initials: A
authors.lastname: Martínez-Tovar
authors.affiliation: Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México.
authors.forename: Irma
authors.initials: I
authors.lastname: Olarte-Carrillo
authors.affiliation: Servicio de Hematología, Hospital General de México Dr. Eduardo Liceaga, Ciudad de México, México.
authors.forename: Juan
authors.initials: J
authors.lastname: Collazo-Jaloma
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002947:Cities; D005260:Female; D006801:Humans; D007223:Infant; D007938:Leukemia / Q000453:epidemiology*; D008297:Male; D008800:Mexico / Q000453:epidemiology; D008875:Middle Aged; D012017:Referral and Consultation; D012189:Retrospective Studies; D017678:Sex Distribution; D014504:Urban Health; D055815:Young Adult