title: Products with Natural Components to Heal Dermal Burns: A Patent Review.
abstract: BACKGROUND
  Burns are a global public health problem, and non-fatal burn injuries are a leading cause of morbidity. The scale of the problem has led researchers to seek to develop new prod- ucts (both synthetic and natural) for use in the treatment of burn lesions.
  
  
  OBJECTIVE
  The aim of this study was to examine all patents in databases between 2010 and 2015 related to natural prod- ucts for the treatment of burn-related wounds that targeted tissue repair and healing.
  
  
  METHODS
  The search term "burn" and the code A61K36/00 (plant and other natural derivatives used in medicinal prepara- tions) from the international classification of patents were used to identify treatments.
  
  
  RESULTS
  The search was performed in the WIPO, ESPACENET and USPTO databases. The highest number of patent ap- plications was found in the WIPO data base (617), followed by ESPACENET(23) and USPTO(6). The USA and China were the countries with the most patent applications, and 2008 was the year that had the highest number of applications. Patent applications written in Spanish, English and Portuguese and that were published between 2010 and 2015 were se- lected. 559 patent applications in other languages, and 63 that did not result in the creation of new products between 2010 and 2015 were excluded and the remaining 13 patents application were selected for full reading of the text.
  
  
  CONCLUSIONS
  Through this study we were able to identify and summarize the new active natural compounds that can be used in the treatment of burns, both in terms of tissue recovery and analgesia.
authors.forename: Aida Carla Santana
authors.initials: AC
authors.lastname: de Melo Costa
authors.forename: Karen Perez
authors.initials: KP
authors.lastname: Pereira Ramos
authors.forename: Mairim Russo
authors.initials: MR
authors.lastname: Serafini
authors.forename: Fernanda Oliveira
authors.initials: FO
authors.lastname: de Carvalho
authors.forename: Luciana Garcez Barretto
authors.initials: LG
authors.lastname: Teixeira
authors.forename: Diogo Costa
authors.initials: DC
authors.lastname: Garcao
authors.forename: Saravanan
authors.initials: S
authors.lastname: Shanmugam
authors.forename: Adriano Antunes
authors.initials: AA
authors.lastname: de Souza Araujo
authors.affiliation: Department of Morphology, Federal University of Sergipe, MarechalRondom Avenue s/n, CEP 49100-000, Sao Cristovao-SE, Brazil. paulanunes_se@yahoo.com.br.
authors.forename: Paula Santos
authors.initials: PS
authors.lastname: Nunes
mesh_terms: D001688:Biological Products / Q000627:therapeutic use*; D002056:Burns / Q000188:drug therapy*; D006801:Humans; D010330:Patents as Topic; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D001688:Biological Products