title: Movement-related potentials in Parkinson's disease.
abstract: To date, many different approaches have been used to study the impairment of motor function in Parkinson's disease (PD). Event-related potentials (ERPs) are averaged amplitude fluctuations of the ongoing EEG activity that are time locked to specific sensory, motor or cognitive events, and as such can be used to study different brain processes with an excellent temporal resolution. Movement-related potentials (MRPs) are ERPs associated with processes of voluntary movement preparation and execution in different paradigms. In this review we concentrate on MRPs in PD. We review studies recording the Bereitschaftspotential, the Contingent Negative Variation, and the lateralized readiness potential in PD to highlight the contributions they have made to further understanding motor deficits in PD. Possible directions for future research are also discussed.
authors.affiliation: Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, UK; Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia.
authors.forename: Dejan
authors.initials: D
authors.lastname: Georgiev
authors.affiliation: Department of Neurology, Hannover Medical School, Hannover, Germany.
authors.forename: Florian
authors.initials: F
authors.lastname: Lange
authors.affiliation: Department of Neurology, Hannover Medical School, Hannover, Germany.
authors.forename: Caroline
authors.initials: C
authors.lastname: Seer
authors.affiliation: Department of Neurology, Hannover Medical School, Hannover, Germany.
authors.forename: Bruno
authors.initials: B
authors.lastname: Kopp
authors.affiliation: Sobell Department of Motor Neuroscience and Movement Disorders, Institute of Neurology, University College London, UK. Electronic address: m.jahanshahi@ucl.ac.uk.
authors.forename: Marjan
authors.initials: M
authors.lastname: Jahanshahi
mesh_terms: D005071:Evoked Potentials; D019054:Evoked Potentials, Motor; D006801:Humans; D009068:Movement; D010300:Parkinson Disease / Q000503:physiopathology*
keywords: Bereitschaftspotential; Contingent Negative Variation; Lateralized readiness potential; Movement-related potentials; Parkinson’s disease