title: Another gastroenteritis?
abstract: Portal vein thrombosis (PVT) is an important, but often delayed or missed differential diagnosis in patients presenting with abdominal pain. In this case report we present a previously healthy 42-year-old patient with persistent upper abdominal pain for five days. Being a common complication in patients suffering from liver cirrhosis, PVT is an unusual finding in healthy individuals. However, gene mutation leading to a hypercoagulable state can be associated with thrombotic events in the portal venous system. Investigation for underlying disorders such as myeloproliferative neoplasm (MPN), paroxysmal nocturnal hemoglobinuria (PNH), antiphospholipid antibody syndrome are crucial.
authors.affiliation: 1 Department of Anaesthesiology and Surgical Intensive Care Unit, University Hospital of Tongji University, Yangpu Central Hospital, Shanghai, China.
authors.forename: Ewelina
authors.initials: E
authors.lastname: Biskup
authors.affiliation: 2 International Department, Shanghai East Hospital, Shanghai, China.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Necek
authors.affiliation: 1 Department of Anaesthesiology and Surgical Intensive Care Unit, University Hospital of Tongji University, Yangpu Central Hospital, Shanghai, China.
authors.forename: Qu
authors.initials: Q
authors.lastname: Changjin
mesh_terms: D015746:Abdominal Pain / Q000209:etiology*; D000328:Adult; D004252:DNA Mutational Analysis; D003937:Diagnosis, Differential; D005759:Gastroenteritis / Q000175:diagnosis*; D006801:Humans; D008297:Male; D065666:Mesenteric Ischemia / Q000175:diagnosis* / Q000235:genetics; D011169:Portal Vein; D011516:Prothrombin / Q000235:genetics; D012008:Recurrence; D013927:Thrombosis / Q000175:diagnosis* / Q000235:genetics; D014057:Tomography, X-Ray Computed
chemical_list: D011516:Prothrombin
keywords: Faktor V Leiden; Pfortaderthrombose; Prothrombin-Gen-Mutation; Thrombophilie; factor V Leiden; portal vein thrombosis; prothrombin gene mutation; recurrent venous thromboembolism; rezidivierende venöse Thromboembolien; thrombophilia