title: Proposed cut-off values of the waist circumference for metabolic syndrome based on visceral fat volume in a Japanese population.
abstract: OBJECTIVE
  Waist circumference (WC) is the most important parameter for diagnosis of metabolic syndrome. The present study was carried out to obtain optimal WC cut-off values for diagnosis of metabolic syndrome in a Japanese population based on the measurement of total intra-abdominal visceral fat volume (VFV), which could be expected to reflect visceral obesity more precisely than visceral fat area.
  
  
  METHODS
  A total of 405 Japanese persons undergoing health screening were investigated. visceral fat volume was calculated from the data in 700-800 computed tomography slices from the top of the liver to the floor of the pelvic cavity. Then, receiver operating characteristic analysis was used to determine the cut-off value of the VFV/height ratio. Subsequently, the corresponding WC value was obtained by linear regression analysis.
  
  
  RESULTS
  The cut-off value of the VFV/height ratio was 2,317 cm(3) /m in men and 1,425 cm(3) /m in women. The sensitivity and specificity of the ratio were 52.9 and 86.4% in men vs 63.4 and 82.2% in women, respectively. The corresponding cut-off value of WC was 86.0 cm in men and 80.9 cm in women.
  
  
  CONCLUSIONS
  The proposed cut-off values of WC for metabolic syndrome are 85 cm in Japanese men and 80 cm in Japanese women.
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.|International University of Health and Welfare Hospital, Nasushiobara, Japan.
authors.forename: Hidekazu
authors.initials: H
authors.lastname: Tsukiyama
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.|International University of Health and Welfare Hospital, Nasushiobara, Japan.
authors.forename: Yoshio
authors.identifier: http://orcid.org/0000-0002-7065-6545
authors.initials: Y
authors.lastname: Nagai
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.|International University of Health and Welfare Hospital, Nasushiobara, Japan.
authors.forename: Fumiaki
authors.initials: F
authors.lastname: Matsubara
authors.affiliation: International University of Health and Welfare Hospital, Nasushiobara, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Shimizu
authors.affiliation: International University of Health and Welfare Hospital, Nasushiobara, Japan.
authors.forename: Teruaki
authors.initials: T
authors.lastname: Iwamoto
authors.affiliation: International University of Health and Welfare Hospital, Nasushiobara, Japan.
authors.forename: Eigoro
authors.initials: E
authors.lastname: Yamanouchi
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: Yukiyoshi
authors.initials: Y
authors.lastname: Sada
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Kato
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Ohta
authors.affiliation: Division of Metabolism and Endocrinology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Tanaka
mesh_terms: D044466:Asian People; D005260:Female; D006801:Humans; D050152:Intra-Abdominal Fat / Q000000981:diagnostic imaging*; D007564:Japan / Q000453:epidemiology; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D008875:Middle Aged; D056128:Obesity, Abdominal / Q000150:complications / Q000175:diagnosis* / Q000453:epidemiology; D012372:ROC Curve; D012016:Reference Values; D055105:Waist Circumference
keywords: Metabolic syndrome; Visceral fat volume; Waist circumference