title: [THE FORMATION OF BIOFILM IN OPPORTUNISTIC MICROORGANISMS IN BLOOD PLASMA DEPENDING ON CONTENT OF IRON].
abstract: The article considers results of analysis offormation of biofilm of priority opportunistic pathogens in blood plasma and LB-broth. As compared with LB-broth, bloodplasma stimulates formation of biofilm of microorganisms in the following sequence: Staphylococcus aureus > Pseudomonas aeruginosa > Escherichia coli. The application oftechnique of infra-redspectroscopy of bio-films established that blood plasma promotes formation of external exopolysaccharides of S.aureus. The cultivation of bio-films in plasma depending on content of iron demonstrated that the analyzed strains of S. aureus, P. aeruginosa, E. coli form bio-films in a better way in plasma with normal content of iron and iron-deficient and iron-loaded plasma decreases their activity of formation of biofilm.
authors.forename: V V
authors.initials: VV
authors.lastname: Leonov
authors.forename: A Yu
authors.initials: AY
authors.lastname: Mironov
mesh_terms: D000328:Adult; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D004926:Escherichia coli / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology*; D004927:Escherichia coli Infections / Q000382:microbiology; D006801:Humans; D007501:Iron / Q000097:blood* / Q000494:pharmacology; D008297:Male; D009894:Opportunistic Infections / Q000382:microbiology; D011135:Polysaccharides, Bacterial / Q000096:biosynthesis; D011552:Pseudomonas Infections / Q000382:microbiology; D011550:Pseudomonas aeruginosa / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology*; D012426:Russia; D017550:Spectroscopy, Fourier Transform Infrared; D013203:Staphylococcal Infections / Q000382:microbiology; D013211:Staphylococcus aureus / Q000187:drug effects / Q000302:isolation & purification / Q000502:physiology*
chemical_list: D011135:Polysaccharides, Bacterial; D007501:Iron