title: Unlocking the code: mining the urinary proteome after renal transplantation.
abstract: Diagnosis of transplant dysfunction usually requires kidney biopsy. Sidgel et al. compared urinary proteomics with matched kidney biopsies to develop a biomarker panel to differentiate acute rejection, BK viral nephropathy, and chronic allograft nephropathy. The results suggest that monitoring a panel of urinary peptides may ultimately facilitate noninvasive diagnosis and management of common transplant complications.
authors.affiliation: Department of Nephrology, Prince of Wales Hospital and Clinical School, University of New South Wales, Sydney, Australia. Electronic address: z.endre@unsw.edu.au.
authors.forename: Zoltan H
authors.initials: ZH
authors.lastname: Endre
authors.affiliation: Department of Nephrology, Prince of Wales Hospital and Clinical School, University of New South Wales, Sydney, Australia.
authors.forename: Mangalee
authors.initials: M
authors.lastname: Fernando
mesh_terms: D001739:BK Virus; D006084:Graft Rejection; D006801:Humans; D007668:Kidney; D016030:Kidney Transplantation; D020543:Proteome; D014551:Urinary Tract
chemical_list: D020543:Proteome