title: Nutrition in Cardioskeletal Health.
abstract: Bone and heart health are linked through a variety of cellular, endocrine, and metabolic mechanisms, including the bidirectional effects of mineral-regulating hormones parathyroid hormone and fibroblast growth factor 23. Nutrition plays an important role in the development of both cardiovascular and bone disease. This review describes current knowledge on the relations between the cardiovascular system and bone and the influence of key nutrients involved in mineral metabolism-calcium, vitamin D, and phosphorus-on heart and bone health, as well as the racial/ethnic differences in cardiovascular disease and osteoporosis and the influence that nutrition has on these disparities.
authors.affiliation: Department of Nutrition Science, Purdue University, West Lafayette, IN; hillgallant@purdue.edu.
authors.forename: Kathleen M
authors.initials: KM
authors.lastname: Hill Gallant
authors.affiliation: Department of Nutrition Science, Purdue University, West Lafayette, IN;
authors.forename: Connie M
authors.initials: CM
authors.lastname: Weaver
authors.affiliation: Internal Medicine/Endocrine Division, University of Texas Southwestern Medical Center, Dallas, TX; and.
authors.forename: Dwight A
authors.initials: DA
authors.lastname: Towler
authors.affiliation: Department of Nutrition Science, Purdue University, West Lafayette, IN;
authors.forename: Sowmyanarayanan V
authors.initials: SV
authors.lastname: Thuppal
authors.affiliation: Department of Nutrition Science, Purdue University, West Lafayette, IN; Office of Dietary Supplements, National Institutes of Health, Bethesda, MD.
authors.forename: Regan L
authors.initials: RL
authors.lastname: Bailey
mesh_terms: D001842:Bone and Bones; D002118:Calcium / Q000378:metabolism*; D002318:Cardiovascular Diseases / Q000209:etiology / Q000378:metabolism; D004032:Diet; D000089703:Fibroblast Growth Factor-23; D005346:Fibroblast Growth Factors / Q000378:metabolism; D054624:Health Status Disparities; D006321:Heart; D006801:Humans; D008903:Minerals; D010024:Osteoporosis / Q000209:etiology / Q000378:metabolism; D010281:Parathyroid Hormone / Q000378:metabolism; D010758:Phosphorus / Q000378:metabolism*; D014807:Vitamin D / Q000378:metabolism*
chemical_list: D008903:Minerals; D010281:Parathyroid Hormone; D014807:Vitamin D; D010758:Phosphorus; D005346:Fibroblast Growth Factors; D000089703:Fibroblast Growth Factor-23; D002118:Calcium
keywords: bone health; calcium; cardiovascular diseases; phosphorus; vitamin D