title: Surgical treatment of congenital cystic adenomatoid malformation: a retrospective study of single tertiary center experience.
abstract: OBJECTIVE
  To summarize the experience drawn from treatment of fetus with congenital cystic adenomatoid malformation (CCAM).
  
  
  METHODS
  This retrospective report has reviewed a clinical history of 115 patients with CCAM from September 2012 to June 2014. All cases were divided into two groups according to symptomatology: group A (n = 96, asymptomatic group) and group B (n = 19, symptomatic group). Major factors were compared between two groups. Numerical data were presented as the median (range). The difference between median was performed with ANOVA.
  
  
  RESULTS
  The mean gestational age of prenatal diagnosis was 24.3 weeks (range, 17-36). 49 cases with CCAM volume ratio (CVR) were retrospectively analyzed, with a median max CVR of 0.95 (range, 0.19-3.2), In the 115 cases, mean operation age was (3.7 ± 0.32) months old. Symptom is significantly associated with lesion size and chest radiographs (CXR) (p < 0.05). Compared with symptomatic CCAM patients, asymptomatic patients were associated with better clinical outcome.
  
  
  CONCLUSIONS
  The value of CVR to evaluate prognosis showed no statistical significance. Although CXR are not reliable indicators to assess the lesion, it can predict the emergency situation. Due to potential trend of symptomatic and poor postoperative symptoms group, early postnatal CT scan and early surgical treatment are suggested.
authors.affiliation: a Department of Maternal-Fetal Medicine , Guangdong Women and Children Hospital, Guangzhou Medical University , Guangzhou , China.
authors.forename: Bo
authors.initials: B
authors.lastname: Xia
authors.affiliation: a Department of Maternal-Fetal Medicine , Guangdong Women and Children Hospital, Guangzhou Medical University , Guangzhou , China.
authors.forename: Gang
authors.initials: G
authors.lastname: Yu
authors.affiliation: a Department of Maternal-Fetal Medicine , Guangdong Women and Children Hospital, Guangzhou Medical University , Guangzhou , China.
authors.forename: Cuifen
authors.initials: C
authors.lastname: Liu
authors.affiliation: a Department of Maternal-Fetal Medicine , Guangdong Women and Children Hospital, Guangzhou Medical University , Guangzhou , China.
authors.forename: Chun
authors.initials: C
authors.lastname: Hong
authors.affiliation: a Department of Maternal-Fetal Medicine , Guangdong Women and Children Hospital, Guangzhou Medical University , Guangzhou , China.
authors.forename: Jing
authors.initials: J
authors.lastname: Tang
mesh_terms: D000704:Analysis of Variance; D015615:Cystic Adenomatoid Malformation of Lung, Congenital / Q000000981:diagnostic imaging / Q000601:surgery*; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007902:Length of Stay; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D012189:Retrospective Studies; D012720:Severity of Illness Index; D062606:Tertiary Care Centers; D013997:Time Factors; D014057:Tomography, X-Ray Computed; D016216:Ultrasonography, Prenatal
keywords: Congenital cystic adenomatoid malformation; fetus; surgery