title: Prostate Cancer With Metastatic Lytic Bone Lesions: Positive Bone Scan Post Docetaxel Chemotherapy in the Setting of Clinically Successful Treatment.
abstract: Current treatment of metastatic bone prostate cancer with Docetaxel chemotherapy per CHAARTED trial is standard of care. Timing of CT and bone scintigraphy for evaluation of successful treatment of lytic lesions is not available in the literature. We present a case of a 70 year old male with PSA of 586 and wide spread metastatic bone lytic lesions, who underwent androgen deprivation therapy and six cycles of Docetaxel chemotherapy. The patient had clinically successful treatment. Contrast enhanced CT scan demonstrated sclerotic bone lesions with PSA 2.5 at this point in treatment; however, 99mTc-MDP bone scintigraphy remained positive for metastatic lesions.
authors.affiliation: University of Florida, Gainesville, Florida, United States.
authors.forename: Victoria Yvonne
authors.initials: VY
authors.lastname: Bird
authors.affiliation: University of Florida, Department of Urology, United States.
authors.forename: Paula M
authors.initials: PM
authors.lastname: Domino
authors.affiliation: University of Florida, Department of Radiology, United States.
authors.forename: Raymond
authors.initials: R
authors.lastname: Sutkowski
authors.affiliation: University of Florida, School of Medicine, United States.
authors.forename: Stephanie A
authors.initials: SA
authors.lastname: Stillings
authors.affiliation: University of Florida, Department of Pathology, United States.
authors.forename: Jorge A
authors.initials: JA
authors.lastname: Trejo-Lopez
keywords: Bone-scan; Docetaxel; Lytic; Prostate