title: [Urothelial-type mucinous adenocarcinoma of the prostate: A case report and review of the literature].
abstract: OBJECTIVE
  To investigate the clinical manifestations, pathological characteristics, and treatments of urothelial-type mucinous adenocarcinoma of the prostate (UMAP).
  
  
  METHODS
  We reported a case of UMAP, reviewed relevant literature, and analyzed the clinicopaothological features, diagnosis, treatment, and prognosis of the disease.
  
  
  RESULTS
  The patient was a 60-year-old male and underwent transurethral resection of the prostate for dysuria. Postoperative pathology indicated mucinous adenocarcinoma and sigmoidoscopy revealed no primary colon cancer. Immunohistochemical staining showed the negative expressions of PSA and P504s and positive expressions of CK7, CK34 β E12, CK20, and CDX2. Thus UMAP was confirmed and treated by intensity-modulated radiotherapy. Then the patient was followed up for 30 months, which showed desirable therapeutic result, with neither local progression nor distant metastasis.
  
  
  CONCLUSIONS
  UMAP has a bad prognosis and its diagnosis depends on pathological and immunohistocchemical examinations. It responds well to radical prostatectomy but is not sensitive to endocrine therapy. Radiotherapy can be considered for those who are not fit to receive radical prostatectomy.
authors.forename: Yong-shun
authors.initials: YS
authors.lastname: Guo
authors.forename: Su-mei
authors.initials: SM
authors.lastname: Gao
authors.forename: Ming-rong
authors.initials: MR
authors.lastname: Zhang
authors.forename: Ju-min
authors.initials: JM
authors.lastname: Zhang
authors.forename: Yun-jiang
authors.initials: YJ
authors.lastname: Zang
authors.forename: Hong-kai
authors.initials: HK
authors.lastname: Lu
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D006801:Humans; D007633:Keratins / Q000378:metabolism; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000378:metabolism; D011379:Prognosis; D011468:Prostatectomy; D011471:Prostatic Neoplasms / Q000378:metabolism / Q000473:pathology / Q000628:therapy; D019998:Racemases and Epimerases / Q000378:metabolism
chemical_list: C121278:CK-34 beta E12; D009363:Neoplasm Proteins; D007633:Keratins; D019998:Racemases and Epimerases; C108352:alpha-methylacyl-CoA racemase