title: Rational Hyperoxia in the Perioperative Period: a Safe and Effective Tool in the Reduction of SSI.
abstract: Oxygen supplemented at a concentration higher than 40-50 % for at least 2 h perioperatively is expected to reduce surgical site infections (SSI). Although supplementation of 80 % of oxygen perioperatively has shown to reduce SSI in various studies, this concentration is known to be associated with airway complications. This study was taken up to assess the efficacy of 60 %, i.e. <80 and >50 %, inspired oxygen supplemented perioperatively in reducing SSI. One hundred and eighty-eight patients who underwent elective class I and II surgeries were studied. Patients were divided equally into two groups and subgroups and matched for age, sex, type of surgeries, etc. The control group received 30 % and the study group received 60 % oxygen supplementation perioperatively for 2 h. Wounds were observed for the development of SSI. 8/94 patients in the study group and 13/94 patients in the control group developed SSI (p < 0.01). The results indicate a relative risk of 1.62, risk difference of 0.0531 and attributable risk of 38.42 %. Hence, it may be concluded that perioperative oxygen supplementation at 60 % concentration reduces SSI.
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Tejaswini
authors.initials: T
authors.lastname: Vallabha
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Uday
authors.initials: U
authors.lastname: Karjol
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Vijayakumar
authors.initials: V
authors.lastname: Kalyanappagol
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Vikram
authors.initials: V
authors.lastname: Sindgikar
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Ravindra
authors.initials: R
authors.lastname: Nidoni
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Harshavardhan
authors.initials: H
authors.lastname: Biradar
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: Aniketan
authors.initials: A
authors.lastname: K V
authors.affiliation: Department of Surgery, Shri BM Patil Medical College & Research Centre, BLDE University, Sholapur Road, Vijayapura (Bijapur), Karnataka 586103 India.
authors.forename: K K
authors.initials: KK
authors.lastname: Das
keywords: 60 % inspired oxygen; Hyperoxia; Perioperative oxygen supplementation; Surgical site infections