title: Auxiliary partial orthotopic liver transplant for Criggler-Najjar Syndrome: Report of 2 cases from Pakistan.
abstract: Auxiliary partial orthotopic liver transplant (APOLT) is a treatment option for certain liver disorders where liver structure is preserved. It includes Criggler Najjar syndrome (CNS), urea cycle defects and familial hypercholesterolaemia. Liver transplant as a treatment modality has only recently become available in Pakistan. Here we report two paediatric cases of CNS type 1 where auxiliary liver transplant was performed to correct jaundice and prevent inevitable brain damage. Both recipients and their respective living donors had successful surgery and are doing well.
authors.affiliation: HPB and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan.
authors.forename: Faisal Saud
authors.initials: FS
authors.lastname: Dar
authors.affiliation: HPB and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan.
authors.forename: Abu Bakar Hafeez
authors.initials: AB
authors.lastname: Bhatti
authors.affiliation: Department of Paediatrics and Paediatric Hepatology, Shifa International Hospital, Islamabad, Pakistan.
authors.forename: Syeda Shaheera
authors.initials: SS
authors.lastname: Hashmi
authors.affiliation: HPB and Liver Transplantation, Shifa International Hospital, Islamabad, Pakistan.
authors.forename: Haseeb
authors.initials: H
authors.lastname: Zia
authors.affiliation: Department of Paediatrics and Paediatric Hepatology, Shifa International Hospital, Islamabad, Pakistan.
authors.forename: Munir Iqbal
authors.initials: MI
authors.lastname: Malik
mesh_terms: D009202:Cardiomyopathies / Q000601:surgery*; D002648:Child; D005260:Female; D005835:Genitalia / Q000002:abnormalities* / Q000601:surgery; D006801:Humans; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D016896:Treatment Outcome
keywords: Transplantation, Liver, Graft, Criggler Najjar Syndrome