title: Incidence of Cystoid Macular Edema After Descemet Membrane Endothelial Keratoplasty as a Staged and Solitary Procedure.
abstract: OBJECTIVE
  To compare the incidence of visually significant postoperative cystoid macular edema (CME) in pseudophakic eyes after Descemet membrane endothelial keratoplasty (DMEK) performed after recent versus remote cataract surgery.
  
  
  METHODS
  A retrospective chart review was performed of all consecutive eyes that underwent DMEK without concurrent cataract surgery at the University of Iowa between October 2012 and December 2014. The DMEK procedures were classified as staged if performed between 2 weeks and 6 months after cataract surgery and solitary if performed more than 6 months after cataract surgery. Possible confounders, including a history of diabetes in the recipient, were tracked. Macular optical coherence tomography was performed to detect CME 1 month after DMEK if the best-corrected visual acuity was ≤20/30 with a clear cornea with no other reason for visual compromise.
  
  
  RESULTS
  A total of 173 eyes from 140 patients were included in the statistical analysis. Staged DMEK was performed in 88 eyes (50.8%) and solitary DMEK in 85 eyes (49.2%). The incidence of CME was 8.0% (7 of 88 eyes) in the staged DMEK group and 7.1% (6 of 85 eyes) in the solitary DMEK group (P = 0.823). The incidence of CME did not differ significantly between the staged and solitary DMEK groups regardless of the recipient diabetic status. All cases of CME resolved within 6 months on topical therapy.
  
  
  CONCLUSIONS
  The incidence of postoperative CME after DMEK is similar in the setting of recent or remote cataract surgery.
authors.affiliation: *Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, IA; †Cornea Research Center, Stephen A. Wynn Institute for Vision Research, Department of Ophthalmology and Visual Sciences, University of Iowa Carver College of Medicine, Iowa City, IA; and ‡Department of Biostatistics, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: William E
authors.initials: WE
authors.lastname: Flanary
authors.forename: Jesse M
authors.initials: JM
authors.lastname: Vislisel
authors.forename: Michael D
authors.initials: MD
authors.lastname: Wagoner
authors.forename: Matthew E
authors.initials: ME
authors.lastname: Raecker
authors.forename: Benjamin T
authors.initials: BT
authors.lastname: Aldrich
authors.forename: M Bridget
authors.initials: MB
authors.lastname: Zimmerman
authors.forename: Kenneth M
authors.initials: KM
authors.lastname: Goins
authors.forename: Mark A
authors.initials: MA
authors.lastname: Greiner
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002387:Cataract Extraction; D057111:Descemet Stripping Endothelial Keratoplasty / Q000009:adverse effects*; D005260:Female; D006801:Humans; D015994:Incidence; D008269:Macular Edema / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications; D019591:Pseudophakia / Q000209:etiology; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence