title: Electron Beam Melting Manufacturing Technology for Individually Manufactured Jaw Prosthesis: A Case Report.
abstract: In the field of maxillofacial reconstruction, additive manufacturing technologies, specifically electron beam melting (EBM), offer clinicians the potential for patient-customized design of jaw prostheses, which match both load-bearing and esthetic demands. The technique allows an innovative, functional design, combining integrated porous regions for bone ingrowth and secondary biological fixation with solid load-bearing regions ensuring the biomechanical performance. A patient-specific mandibular prosthesis manufactured using EBM was successfully used to reconstruct a patient's mandibular defect after en bloc resection. Over a 9-month follow-up period, the patient had no complications. A short operating time, good esthetic outcome, and high level of patient satisfaction as measured by quality-of-life questionnaires-the European Organisation for Research and Treatment of Cancer QLQ-C30 (30-item quality-of-life core questionnaire) and H&N35 (head and neck cancer module)-were reported for this case. Individually planned and designed EBM-produced prostheses may be suggested as a possible future alternative to fibular grafts or other reconstructive methods. However, the role of porosity, the role of geometry, and the optimal combination of solid and porous parts, as well as surface properties in relation to soft tissues, should be carefully evaluated in long-term clinical trials.
authors.affiliation: Department of Oral and Maxillofacial Surgery and Department of Biomaterials, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; and BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden. Electronic address: felicia.suska@biomaterials.gu.se.
authors.forename: Felicia
authors.initials: F
authors.lastname: Suska
authors.affiliation: Associate Professor, Department of Oral and Maxillofacial Surgery, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Göran
authors.initials: G
authors.lastname: Kjeller
authors.affiliation: Associate Professor, Department of Plastic Surgery, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
authors.forename: Peter
authors.initials: P
authors.lastname: Tarnow
authors.affiliation: Associate Professor, Department of Materials and Manufacturing Technologies, Chalmers University of Technology, Gothenburg, Sweden.
authors.forename: Eduard
authors.initials: E
authors.lastname: Hryha
authors.affiliation: Professor, Department of Materials and Manufacturing Technologies, Chalmers University of Technology, Gothenburg, Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Nyborg
authors.affiliation: BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden; and Arcam AB, Mölndal, Sweden.
authors.forename: Anders
authors.initials: A
authors.lastname: Snis
authors.affiliation: Associate Professor, Department of Biomaterials, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden; and BIOMATCELL VINN Excellence Center of Biomaterials and Cell Therapy, Gothenburg, Sweden.
authors.forename: Anders
authors.initials: A
authors.lastname: Palmquist
mesh_terms: D000369:Aged, 80 and over; D004583:Electrons; D005260:Female; D006801:Humans; D008339:Mandibular Neoplasms / Q000601:surgery*; D063175:Mandibular Reconstruction / Q000379:methods*; D008420:Manufactured Materials; D017060:Patient Satisfaction; D019736:Prostheses and Implants; D011474:Prosthesis Design; D011788:Quality of Life; D013499:Surface Properties; D013524:Surgical Flaps; D014057:Tomography, X-Ray Computed