title: Translational studies for exercise in high-risk pregnancy: Pre-eclampsia model.
abstract: OBJECTIVE
  Reviewed literature regarding exercise effects on pregnancy-related hypertensive disorders, analyzing basic science perspectives and clinical studies.
  
  
  METHODS
  Scientific databases were accessed by research strategy combining Medical Subject Headings terms. Studies published between 2000 and 2015, in English, Portuguese, and Spanish language, were considered.
  
  
  RESULTS
  Studies were classified into: recommendations for exercise on high-risk pregnancy; animal models for hypertension in pregnancy; exercise on hypertensive disorders in animal models and pregnant women.
  
  
  CONCLUSIONS
  There are several animal models to mimic hypertensive disorders in pregnancy; however, clinical studies are still needed for exercise recommendation in pregnant women with hypertensive disorders.
authors.affiliation: a Department of Obstetrics and Gynecology , University of Campinas (UNICAMP) , Campinas , SP , Brazil.
authors.forename: Karina Tamy
authors.initials: KT
authors.lastname: Kasawara
authors.affiliation: a Department of Obstetrics and Gynecology , University of Campinas (UNICAMP) , Campinas , SP , Brazil.
authors.forename: Fernanda Garanhani
authors.initials: FG
authors.lastname: Surita
authors.affiliation: a Department of Obstetrics and Gynecology , University of Campinas (UNICAMP) , Campinas , SP , Brazil.
authors.forename: João Luiz
authors.initials: JL
authors.lastname: Pinto E Silva
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D015444:Exercise / Q000502:physiology*; D005081:Exercise Therapy; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000503:physiopathology / Q000517:prevention & control*; D011247:Pregnancy; D018566:Pregnancy, High-Risk
keywords: High-risk pregnancy; motor activity; pre-eclampsia; pregnancy-induced hypertension; translational medical research