title: Effect of Body Mass Index on Blood Transfusion in Total Hip and Knee Arthroplasty.
abstract: Perioperative blood management remains a challenge during total hip arthroplasty (THA) and total knee arthroplasty (TKA). The purpose of this study was to systematically examine the relationship between body mass index (BMI) and perioperative blood transfusion during THA and TKA while attempting to resolve conflicting results in previously published studies. The authors retrospectively evaluated 2399 patients, 896 of whom underwent THA and 1503 of whom underwent TKA. Various outcome variables were assessed for their relationship to BMI, which was stratified using the World Health Organization classification scheme (normal, <25 kg/m(2); overweight, 25-30 kg/m(2); obese, >30 kg/m(2)). Among patients undergoing THA, transfusion rates were 34.8%, 27.6%, and 21.9% for normal, overweight, and obese patients, respectively (P=.002). Among patients undergoing TKA, transfusion rates were 17.3%, 11.4%, and 8.3% for normal, overweight, and obese patients, respectively (P=.002). Patients with an elevated BMI have decreased rates of blood transfusion following both THA and TKA. This same cohort also loses a significantly decreased percentage of estimated blood volume. No trends were identified for a relationship between BMI and deep venous thrombosis, pulmonary embolism, myocardial infarction, discharge location, length of stay, 30-day readmission rate, and preoperative hemoglobin level. Elevated BMI was significantly associated with increased estimated blood loss in patients undergoing THA and those undergoing TKA. There was a statistically significant trend toward increased deep surgical-site infection in patients undergoing THA (P=.043). Patients with increased BMI have lower rates of blood transfusion and lose a significantly smaller percentage of estimated blood volume following THA and TKA. [Orthopedics.2016; 39(5):e844-e849.].
authors.forename: Nicholas
authors.initials: N
authors.lastname: Frisch
authors.forename: Nolan M
authors.initials: NM
authors.lastname: Wessell
authors.forename: Michael
authors.initials: M
authors.lastname: Charters
authors.forename: Ed
authors.initials: E
authors.lastname: Peterson
authors.forename: Brett
authors.initials: B
authors.lastname: Cann
authors.forename: Alex
authors.initials: A
authors.lastname: Greenstein
authors.forename: Craig D
authors.initials: CD
authors.lastname: Silverton
mesh_terms: D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects / Q000706:statistics & numerical data*; D019645:Arthroplasty, Replacement, Knee / Q000009:adverse effects / Q000706:statistics & numerical data*; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data*; D001803:Blood Transfusion / Q000706:statistics & numerical data*; D015992:Body Mass Index; D006801:Humans; D009765:Obesity / Q000453:epidemiology; D050177:Overweight / Q000453:epidemiology; D017713:Platelet Transfusion; D011655:Pulmonary Embolism; D012189:Retrospective Studies; D013530:Surgical Wound Infection; D020246:Venous Thrombosis