title: Epidemiology and Health-Related Quality of Life in Hypoparathyroidism in Norway.
abstract: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP.
  
  
  
  Patients with HP and 22q11 deletion syndrome (DiGeorge syndrome) were identified in electronic hospital registries. All identified patients were invited to participate in a survey. Among patients who responded, HRQOL was determined by Short Form 36 and Hospital Anxiety and Depression scale. Autoantibodies were measured and candidate genes (CaSR, AIRE, GATA3, and 22q11-deletion) were sequenced for classification of etiology.
  
  
  
  We identified 522 patients (511 alive) and estimated overall prevalence at 102 per million divided among postsurgical HP (64 per million), nonsurgical HP (30 per million), and pseudo-HP (8 per million). Nonsurgical HP comprised autosomal dominant hypocalcemia (21%), autoimmune polyendocrine syndrome type 1 (17%), DiGeorge/22q11 deletion syndrome (15%), idiopathic HP (44%), and others (4%). Among the 283 respondents (median age, 53 years [range, 9-89], 75% females), seven formerly classified as idiopathic were reclassified after genetic and immunological analyses, whereas 26 (37% of nonsurgical HP) remained idiopathic. Most were treated with vitamin D (94%) and calcium (70%), and 10 received PTH. HP patients scored significantly worse than the normative population on Short Form 36 and Hospital Anxiety and Depression scale; patients with postsurgical scored worse than those with nonsurgical HP and pseudo-HP, especially on physical health.
  
  
  
  We found higher prevalence of nonsurgical HP in Norway than reported elsewhere. Genetic testing and autoimmunity screening of idiopathic HP identified a specific cause in 21%. Further research is necessary to unravel the causes of idiopathic HP and to improve the reduced HRQOL reported by HP patients.
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Marianne C
authors.initials: MC
authors.lastname: Astor
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Kristian
authors.initials: K
authors.lastname: Løvås
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Aleksandra
authors.initials: A
authors.lastname: Debowska
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Erik F
authors.initials: EF
authors.lastname: Eriksen
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Johan A
authors.initials: JA
authors.lastname: Evang
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Christian
authors.initials: C
authors.lastname: Fossum
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Kristian J
authors.initials: KJ
authors.lastname: Fougner
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Synnøve E
authors.initials: SE
authors.lastname: Holte
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Kari
authors.initials: K
authors.lastname: Lima
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Ragnar B
authors.initials: RB
authors.lastname: Moe
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Anne Grethe
authors.initials: AG
authors.lastname: Myhre
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: E Helen
authors.initials: EH
authors.lastname: Kemp
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Bjørn G
authors.initials: BG
authors.lastname: Nedrebø
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Johan
authors.initials: J
authors.lastname: Svartberg
authors.affiliation: Department of Clinical Science (M.C.A., K.L., E.S.H.), University of Bergen, Bergen, Norway; Department of Medicine (M.C.A., K.L., E.S.H.), Haukeland University Hospital, Bergen, Norway; Department of Medicine (A.D.), Vestfold Hospital, Tønsberg, Norway; Department of Endocrinology, Morbid Obesity and Preventive Medicine (E.F.E.), Oslo University Hospital, Oslo, Norway; Section of Specialized Endocrinology (J.A.E.), Oslo University Hospital, Rikshospitalet, Norway; Department of Medicine (C.F.), Innlandet Hospital, Gjøvik, Norway; Department of Endocrinology (K.K.F.), St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway; Department of Medicine (S.E.H.), Sørlandet Hospital, Arendal, Norway; Department of Medicine (K.L.), Akershus University Hospital, University of Oslo, Oslo, Norway; Department of Medicine (R.B.M.), Østfold Hospital, Fredrikstad, Norway; Department of Pediatrics (K.L., A.G.M.), Rikshospitalet, Oslo University Hospital, Oslo, Norway; Department of Oncology and Metabolism (E.H.K.), University of Sheffield, Sheffield, UK; Department of Medicine (B.G.N.), Haugesund Hospital, Haugesund, Norway; Division of Internal Medicine (J.S.), University Hospital of North Norway, Tromsø, Norway; Institute of Clinical Medicine (J.S.), UiT The Arctic University of Norway, Tromsø, Norway.
authors.forename: Eystein S
authors.initials: ES
authors.lastname: Husebye
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D004252:DNA Mutational Analysis; D005260:Female; D006304:Health Status; D006801:Humans; D007011:Hypoparathyroidism / Q000453:epidemiology* / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009664:Norway / Q000453:epidemiology; D016105:Parathyroidectomy / Q000009:adverse effects / Q000706:statistics & numerical data; D011183:Postoperative Complications / Q000453:epidemiology; D011788:Quality of Life; D011795:Surveys and Questionnaires; D014157:Transcription Factors / Q000235:genetics; D055815:Young Adult; D000096927:AIRE Protein
chemical_list: D014157:Transcription Factors; D000096927:AIRE Protein