title: Initial periodontal therapy for the treatment of gingival pregnancy tumor.
abstract: The purpose of this study was to evaluate the clinical efficacy of initial periodontal therapy in gingival pregnancy tumors. Thirty-nine patients diagnosed with gingival tumors of pregnancy between 2007 and 2015 were enrolled in this study. The patients received initial periodontal therapy, then supportive periodontal therapies at 3- to 6-month intervals. The patients underwent follow up for 6 months to 8 years after treatment. After plaque control, supragingival scaling, and root planning, the tumors in 25 patients were gradually eliminated without the necessity of surgery. In 3 patients, tumors <5 mm in size disappeared in a mean time of 3.6 months, 4 patients with tumors 5-10 mm disappeared in a time of 7.5 months, 11 patients with tumors 10-15 mm disappeared in 10.2 months, 6 patients with tumors 15-20 mm disappeared in 15 months, and one patient with a tumor >20 mm disappeared in 20 months. No recurrence of gingival pregnancy tumors was noted during subsequent follow-up. Initial periodontal therapy combined with oral hygiene maintenance is efficacious in treating gingival pregnancy tumors of patients with normal hormone levels, which can potentially serve as an option to avoid surgery.
authors.affiliation: The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, China.|Department of Periodontology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, China.|The Affiliated Huizhou Stomatologic Hospital of Jinan University & Huizhou Stomatologic Hospital, Huizhou, Guangdong Province, China.
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Zhu
authors.affiliation: The Affiliated Huizhou Stomatologic Hospital of Jinan University & Huizhou Stomatologic Hospital, Huizhou, Guangdong Province, China.
authors.forename: Y Q
authors.initials: YQ
authors.lastname: Wang
authors.affiliation: The Affiliated Huizhou Stomatologic Hospital of Jinan University & Huizhou Stomatologic Hospital, Huizhou, Guangdong Province, China.
authors.forename: Y C
authors.initials: YC
authors.lastname: Tang
authors.affiliation: The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, China.|Department of Periodontology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, China.
authors.forename: C Z
authors.initials: CZ
authors.lastname: Li
mesh_terms: D000328:Adult; D005260:Female; D005887:Gingival Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D017789:Granuloma, Pyogenic / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*; D006801:Humans; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy / Q000473:pathology / Q000601:surgery*