title: Efficacy of single voxel 1H MR spectroscopic imaging at 3T for the differentiation of benign and malign breast lesions.
abstract: OBJECTIVE
  The aim of our study was to evaluate the effect of 1H Magnetic Resonance Spectroscopy (MRS) in differentiating breast lesions.
  
  
  METHODS
  Single voxel 1H Magnetic Resonance Spectroscopy (1H-MRS) was performed with 3T magnet in 45 women. The choline cut off point was set semi-quantitavely. Sensitivity, specificity and accuracy of MRS were calculated.
  
  
  RESULTS
  Twenty-four of 25 (96%) malignant and 9 of 26 (35%) benign lesions had choline peak. With the use cutoff value of 19,5 MRS provided a 96% sensitivity, 65% specificity and 80% accuracy.
  
  
  CONCLUSIONS
  MRS has a high diagnostic accuracy in differentiating breast lesions.
authors.affiliation: Marmara University Pendik Education and Research Hospital, Department of Radiology, Istanbul. Electronic address: abdramazan@gmail.com.
authors.forename: Abdullah
authors.initials: A
authors.lastname: Ramazan
authors.affiliation: Marmara University Pendik Education and Research Hospital, Department of Radiology, Istanbul. Electronic address: ozldemircioglu@yahoo.com.
authors.forename: Ozlem
authors.initials: O
authors.lastname: Demircioglu
authors.affiliation: Marmara University Pendik Education and Research Hospital, Department of General Surgery, Istanbul. Electronic address: umitugurlu@gmail.com.
authors.forename: Umit
authors.initials: U
authors.lastname: Ugurlu
authors.affiliation: Marmara University Pendik Education and Research Hospital, Department of Pathology, Istanbul. Electronic address: hkaya@marmara.edu.tr.
authors.forename: Handan
authors.initials: H
authors.lastname: Kaya
authors.affiliation: Marmara University Pendik Education and Research Hospital, Department of Radiology, Istanbul. Electronic address: earibal@gmail.com.
authors.forename: Erkin
authors.initials: E
authors.lastname: Aribal
mesh_terms: D000328:Adult; D000368:Aged; D001940:Breast / Q000000981:diagnostic imaging / Q000473:pathology; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology*; D002794:Choline; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D009682:Magnetic Resonance Spectroscopy / Q000379:methods*; D008875:Middle Aged; D011522:Protons; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D011522:Protons; D002794:Choline
keywords: Biopsy; Breast lesions; Choline peak; MR spectroscopy