title: Non-biased and complete case registration of lymphoid leukemia and lymphoma for five years: a first representative index of Japan from an epidemiologically stable Miyagi Prefecture.
abstract: Previous worldwide epidemiological studies on lymphoid leukemia and/or lymphoma (LL/L) had considerable bias because of difficulty in covering all clinical departments of hospitals in a restricted area (population base). These studies may not have reflected the actual number of newly diagnosed cases (incidence) strictly, or the true LL/L subtype frequencies. We searched all cases of newly diagnosed LL/L in Miyagi Prefecture over a 5-year period, including those that were discovered as LL/L sorely after autopsy. We registered the actual number of 2098 cases in the prefecture and calculated an accurate incidence rate (17.8 per 100,000 persons). Additionally, we identified more realistic and detailed frequencies of LL/L subtypes including the leukemic phase of some lymphomas. As Miyagi Prefecture is an area in which the population dynamics are relatively stable and representative of Japan, the result of our epidemiological study can be used as the first representative index of LL/L for Japan.
authors.affiliation: a Division of Hematopathology , Tohoku University Hospital , Sendai , Japan.|b Department of Anatomic Pathology , Tohoku University Graduate School of Medicine , Sendai , Japan.
authors.forename: Hiroki
authors.initials: H
authors.lastname: Katsushima
authors.affiliation: c Department of Hematology and Rheumatology , Tohoku University Graduate School of Medicine , Sendai , Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Fukuhara
authors.affiliation: c Department of Hematology and Rheumatology , Tohoku University Graduate School of Medicine , Sendai , Japan.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Ichikawa
authors.affiliation: d Department of Pathology , Research Hospital, Institute of Medical Science, University of Tokyo , Tokyo , Japan.
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Ota
authors.affiliation: e Division of Pathology , Cancer Institute Hospital, Japanese Foundation for Cancer Research , Tokyo , Japan.
authors.forename: Kengo
authors.initials: K
authors.lastname: Takeuchi
authors.affiliation: f Department of Hematology and Cell Therapy , Yamagata University Faculty of Medicine , Yamagata , Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Ishizawa
authors.affiliation: b Department of Anatomic Pathology , Tohoku University Graduate School of Medicine , Sendai , Japan.
authors.forename: Hironobu
authors.initials: H
authors.lastname: Sasano
authors.affiliation: c Department of Hematology and Rheumatology , Tohoku University Graduate School of Medicine , Sendai , Japan.
authors.forename: Hideo
authors.initials: H
authors.lastname: Harigae
authors.affiliation: a Division of Hematopathology , Tohoku University Hospital , Sendai , Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Ichinohasama
mesh_terms: D005260:Female; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D007945:Leukemia, Lymphoid / Q000175:diagnosis*; D008223:Lymphoma / Q000453:epidemiology*; D008297:Male; D012042:Registries
keywords: Incidence rate; lymphoid leukemia; lymphoma; registration