title: [Animal models of autoimmune prostatitis and their evaluation criteria].
abstract: Chronic prostatitis is a highly prevalent disease of unclear etiology. Researches show that autoimmune reaction is one cause of the problem. An effective animal model may help a lot to understand the pathogenesis and find proper diagnostic and therapeutic strategies of the disease. Currently used autoimmune prostatitis-related animal models include those of age-dependent spontaneous prostatitis, autoimmune regulator-dependent spontaneous prostatitis, self antigen-induced prostatitis, and steroid-induced prostatitis. Whether an animal model of autoimmune prostatitis is successfully established can be evaluated mainly from the five aspects: histology, morphology, specific antigens, inflammatory factors, and pain intensity.
authors.forename: Jia-ming
authors.initials: JM
authors.lastname: Shen
authors.forename: Jin-chun
authors.initials: JC
authors.lastname: Lu
authors.forename: Bing
authors.initials: B
authors.lastname: Yao
mesh_terms: D000818:Animals; D001327:Autoimmune Diseases / Q000209:etiology* / Q000473:pathology; D002908:Chronic Disease; D004195:Disease Models, Animal; D006801:Humans; D008297:Male; D011472:Prostatitis / Q000209:etiology / Q000276:immunology* / Q000473:pathology; D014157:Transcription Factors; D000096927:AIRE Protein
chemical_list: D014157:Transcription Factors; D000096927:AIRE Protein