title: A multi-responsive turn-on flurogenic probe to sense Zn(2+), Cd(2+) and Pb(2+): left-right-center emission signal swing.
abstract: A versatile new fluorogenic Schiff base probe (L) has been synthesized by the reaction of quinoline-2-carbohydrazide (which acts as the chelating site) and 4-dimethylamino cinnamaldehyde (which acts as the signaling unit). L can sense three of the most biologically and environmentally important metal ions, Zn(2+), Cd(2+) and Pb(2+), among various tested metal ions through selective TURN-ON fluorescence responses in physiological pH. Interestingly, L can not only sense Zn(2+), Cd(2+) and Pb(2+) fluorometrically in physiological conditions but can also distinguish one from another by exhibiting individual intrinsic left-right-center TURN-ON emission signal swings. These selective fluorescence responses were explained by a chelation-enhanced fluorescence (CHEF) mechanism. Theoretical calculations were carried out to ascertain the preferred L-metal ion binding mode.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Guwahati, Assam 781039, India. gdas@iitg.ernet.in.
authors.forename: Soham
authors.initials: S
authors.lastname: Samanta
authors.forename: Barun Kumar
authors.initials: BK
authors.lastname: Datta
authors.forename: Madhurima
authors.initials: M
authors.lastname: Boral
authors.forename: Abhijit
authors.initials: A
authors.lastname: Nandan
authors.forename: Gopal
authors.initials: G
authors.lastname: Das