title: Rare phenolic structures found in the aerial parts of Eriosema laurentii De Wild.
abstract: Recent pharmacological and toxicological investigations of Eriosema laurentii (Leguminosae) have underlined the plausibility of the use of this plant in traditional African medicine. A very complex pattern of phenolic compounds was detected in the tested extracts. Based on these preceding results a detailed phytochemical study was performed and resulted in the isolation and identification of eleven compounds. All are reported in this plant for the first time and four of those are previously undescribed secondary metabolites: 3,4',6,8-tetrahydroxyflavanone-7-C-glucoside and 3,4',6,8-tetrahydroxyflavone-7-C-glucoside with an extremely rare substitution pattern as well as 1-[2,4-dihydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl)phenyl]-3-phenylpropan-1-one and 1-[2,4-dihydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl)phenyl]-3-(4-methoxyphenyl)-propan-1-one. Their structures were elucidated unambiguously by extensive MS- and NMR-experiments.
authors.affiliation: Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon; Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: asybememade@yahoo.fr.
authors.forename: Sylvin Benjamin
authors.initials: SB
authors.lastname: Ateba
authors.affiliation: Laboratory of Animal Physiology, Department of Animal Biology and Physiology, Faculty of Science, University of Yaounde I, P.O. Box 812, Yaounde, Cameroon. Electronic address: dnjamen@gmail.com.
authors.forename: Dieudonné
authors.initials: D
authors.lastname: Njamen
authors.affiliation: Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: claus@gmx.at.
authors.forename: Claus
authors.initials: C
authors.lastname: Gatterer
authors.affiliation: Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: tamili11@gmx.at.
authors.forename: Tamara
authors.initials: T
authors.lastname: Scherzer
authors.affiliation: Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria; Department of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: martin.zehl@univie.ac.at.
authors.forename: Martin
authors.initials: M
authors.lastname: Zehl
authors.affiliation: Institute of Organic Chemistry, University of Vienna, Währingerstraße 38, A-1090 Vienna, Austria. Electronic address: hanspeter.kaehlig@univie.ac.at.
authors.forename: Hanspeter
authors.initials: H
authors.lastname: Kählig
authors.affiliation: Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria. Electronic address: liselotte.krenn@univie.ac.at.
authors.forename: Liselotte
authors.initials: L
authors.lastname: Krenn
mesh_terms: D007887:Fabaceae / Q000737:chemistry*; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification*; D016488:Medicine, African Traditional; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification*; D035261:Plant Components, Aerial / Q000737:chemistry*; D010936:Plant Extracts / Q000737:chemistry
chemical_list: D005960:Glucosides; D010636:Phenols; D010936:Plant Extracts
keywords: 1-[2,4-dihydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl) phenyl]-3-phenylpropan-1-one; 1-[2,4-dihydroxy-3-(2-hydroxy-3-methylbut-3-en-1-yl)phenyl]-3-(4-methoxyphenyl)-propan-1-one; 3,4′,6,8-tetrahydroxyflavanone-7-C-glucoside; 3,4′,6,8-tetrahydroxyflavone-7-C-glucoside; Eriosema laurentii De Wild; Flavonoids; Hydroxybenzoic acids; Leguminosae