title: The Role of FDG-PET/CT in Cervical Cancer: Diagnosis, Staging, Radiation Treatment Planning and Follow-Up.
abstract: Routine screening has lead to significant improvement in the incidence and mortality of cervical cancer in industrialized nations. Current International Federation of Gynecologists and Obstetricians staging is based mainly on clinical examination, with anatomic conventional imaging modalities, such as CT and MR imaging, also being routinely used. Metabolic imaging using 18F-fluoro-2-deoxy-D-glucose(FDG)-PET provides highly specific, noninvasive pretreatment staging and prognostic information regarding post-therapy, and can detect asymptomatic, potentially curable locoregional recurrences. FDG-PET/CT can also optimize the use of advanced radiation treatment planning techniques, such as image-guided intensity modulated radiation therapy, for cervical cancer and may be of value in the development of additional novel approaches, such as stereotactic body radiation therapy.
authors.affiliation: Department of Radiation Oncology, University of Texas Southwestern Medical Center, MC 9183, Dallas, Texas 75390-9183, USA.
authors.forename: Elesyia D
authors.initials: ED
authors.lastname: Haynes-Outlaw
authors.affiliation: Nuclear Medicine and Gynecologic Oncology, Washington University School of Medicine, 4921 Parkview Place, St Louis, MO 63110, USA; Brachytherapy & MicroRT Treatment Center, Mallinckrodt Institute of Radiology, Washington University School of Medicine, 4921 Parkview Place, St Louis, MO 63110, USA. Electronic address: pgrigsby@wustl.edu.
authors.forename: Perry W
authors.initials: PW
authors.lastname: Grigsby
keywords: Cancer staging; Cervical cancer; PET; Radiotherapy treatment planning