title: Anti-Oxidative Activity of Mytiloxanthin, a Metabolite of Fucoxanthin in Shellfish and Tunicates.
abstract: Anti-oxidative activities of mytiloxanthin, a metabolite of fucoxanthin in shellfish and tunicates, were investigated. Mytiloxanthin showed almost the same activities for quenching singlet oxygen and the inhibition of lipid peroxidation as those of astaxanthin, which is a well-known singlet oxygen quencher. Furthermore, mytiloxanthin showed excellent scavenging activity for hydroxyl radicals and this activity was markedly higher than that of astaxanthin.
authors.affiliation: Research Institute for Production Development, 15 Shimogamo, Morimoto Cho, Sakyoku, Kyoto 606-0805, Japan. maoka@mbox.kyoto-inet.or.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Maoka
authors.affiliation: Institute of Health Sciences, Ezaki Glico Co., Ltd., 4-6-5 Utajima, Nishiyodogawa-ku, Osaka 555-8502, Japan. nishino-azusa@gf.glico.co.jp.
authors.forename: Azusa
authors.initials: A
authors.lastname: Nishino
authors.affiliation: Department of Analytical and Bioinorganic Chemistry, Division of Analytical and Physical Chemistry, Kyoto Pharmaceutical University, 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan. yasui@mb.kyoto-phu.ac.jp.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yasui
authors.affiliation: Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan. y-yamano@kobepharma-u.ac.jp.
authors.forename: Yumiko
authors.initials: Y
authors.lastname: Yamano
authors.affiliation: Department of Organic Chemistry for Life Science, Kobe Pharmaceutical University, Motoyamakita-machi, Higashinada-ku, Kobe 658-8558, Japan. a-wada@kobepharma-u.ac.jp.
authors.forename: Akimori
authors.initials: A
authors.lastname: Wada
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D003517:Cyclopentanes / Q000494:pharmacology*; D016166:Free Radical Scavengers / Q000494:pharmacology; D017665:Hydroxyl Radical / Q000378:metabolism; D007659:Ketones / Q000494:pharmacology*; D015227:Lipid Peroxidation / Q000187:drug effects; D010100:Oxygen / Q000378:metabolism; D012758:Shellfish; D026082:Singlet Oxygen / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism; D014561:Urochordata / Q000378:metabolism*; D024341:Xanthophylls / Q000378:metabolism*
chemical_list: D000975:Antioxidants; D003517:Cyclopentanes; D016166:Free Radical Scavengers; D007659:Ketones; D024341:Xanthophylls; C421568:mytiloxanthin; C025164:fucoxanthin; D013481:Superoxides; D026082:Singlet Oxygen; D017665:Hydroxyl Radical; D010100:Oxygen
keywords: anti-oxidative activity; hydroxyl radical; lipid peroxidation; mytiloxanthin; singlet oxygen