title: Evidence generation from healthcare databases: recommendations for managing change.
abstract: There is an increasing reliance on databases of healthcare records for pharmacoepidemiology and other medical research, and such resources are often accessed over a long period of time so it is vital to consider the impact of changes in data, access methodology and the environment. The authors discuss change in communication and management, and provide a checklist of issues to consider for both database providers and users. The scope of the paper is database research, and changes are considered in relation to the three main components of database research: the data content itself, how it is accessed, and the support and tools needed to use the database. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: IMS Health, London, UK.
authors.forename: Alison
authors.identifier: 0000-0002-0005-9016
authors.initials: A
authors.lastname: Bourke
authors.affiliation: Pfizer, Tadworth, UK.
authors.forename: Andrew
authors.initials: A
authors.lastname: Bate
authors.affiliation: University of Utah School of Medicine, Salt Lake City, UT, USA.
authors.forename: Brian C
authors.initials: BC
authors.lastname: Sauer
authors.affiliation: Harvard Medical School, Boston, MA, USA.
authors.forename: Jeffrey S
authors.initials: JS
authors.lastname: Brown
authors.affiliation: Grimsdyke House, London, UK.
authors.forename: Gillian C
authors.initials: GC
authors.lastname: Hall
mesh_terms: D035843:Biomedical Research / Q000379:methods*; D016208:Databases, Factual; D006801:Humans; D017891:Pharmacoepidemiology / Q000379:methods*; D012107:Research Design; D013997:Time Factors
keywords: change management; common data model; database; pharmacoepidemiology; programming; reproducibility; sustainability