title: Monitoring of Antibiotic Residues in Aquatic Products in Urban and Rural Areas of Vietnam.
abstract: Antibiotic residues in aquatic products in Vietnam were investigated. A total of 511 fish and shrimp samples were collected from markets in Ho Chi Minh City (HCMC), Thai Binh (TB), and Nha Trang (NT) from July 2013 to October 2015. The samples were extracted with 2% formic acid in acetonitrile and washed with dispersive C18 sorbent. Thirty-two antibiotics were analyzed by LC-MS/MS. Of the 362 samples from HCMC, antibiotic residues were found in 53 samples. Enrofloxacin was commonly detected, at a rate of 10.8%. In contrast, samples from TB and NT were less contaminated: only 1 of 118 analyzed samples showed residues in TB and only 1 of 31 showed residues in NT. These differences were attributed to the local manufacturing/distribution systems. To understand the current status of antibiotic use and prevent adverse effects that may be caused by their overuse, continual monitoring is required.
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.|Graduate School of Pharmaceutical Sciences, Osaka University , 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Kotaro
authors.initials: K
authors.lastname: Uchida
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Konishi
authors.affiliation: Graduate School of Pharmaceutical Sciences, Osaka University , 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.|Global Collaboration Center, Osaka University , 2-7 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Harada
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.|Graduate School of Pharmaceutical Sciences, Osaka University , 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.|Global Collaboration Center, Osaka University , 2-7 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Okihashi
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.|Graduate School of Pharmaceutical Sciences, Osaka University , 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Yamaguchi
authors.affiliation: Institute of Public Health, Ho Chi Minh City , 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
authors.forename: Mai Hoang Ngoc
authors.initials: MH
authors.lastname: Do
authors.affiliation: Institute of Public Health, Ho Chi Minh City , 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
authors.forename: Long
authors.initials: L
authors.lastname: Thi Bui
authors.affiliation: Institute of Public Health, Ho Chi Minh City , 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
authors.forename: Thinh
authors.initials: T
authors.lastname: Duc Nguyen
authors.affiliation: Institute of Public Health, Ho Chi Minh City , 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
authors.forename: Phuc
authors.initials: P
authors.lastname: Do Nguyen
authors.affiliation: Thai Binh University of Medicine and Pharmacy , 373 Ly Bon Street, Thai Binh, Vietnam.
authors.forename: Diep
authors.initials: D
authors.lastname: Thi Khong
authors.affiliation: Thai Binh University of Medicine and Pharmacy , 373 Ly Bon Street, Thai Binh, Vietnam.
authors.forename: Hoa
authors.initials: H
authors.lastname: Thi Tran
authors.affiliation: Thai Binh University of Medicine and Pharmacy , 373 Ly Bon Street, Thai Binh, Vietnam.
authors.forename: Thang
authors.initials: T
authors.lastname: Nam Nguyen
authors.affiliation: Thai Binh University of Medicine and Pharmacy , 373 Ly Bon Street, Thai Binh, Vietnam.
authors.forename: Ha
authors.initials: H
authors.lastname: Viet Le
authors.affiliation: Nha Trang Pasteur Institute , 8-10 Tran Phu, Xuong Huan Ward, Nha Trang City, Vietnam.
authors.forename: Vien
authors.initials: V
authors.lastname: Van Chau
authors.affiliation: Nha Trang Pasteur Institute , 8-10 Tran Phu, Xuong Huan Ward, Nha Trang City, Vietnam.
authors.forename: Khanh
authors.initials: K
authors.lastname: Thi Van Dao
authors.affiliation: Nha Trang Pasteur Institute , 8-10 Tran Phu, Xuong Huan Ward, Nha Trang City, Vietnam.
authors.forename: Hue
authors.initials: H
authors.lastname: Thi Ngoc Nguyen
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
authors.forename: Keiji
authors.initials: K
authors.lastname: Kajimura
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Kumeda
authors.affiliation: Vietnam Food Administration, Viet Nam Ministry of Health , 138A Giang Vo Street, Ba Dinh District, Ha Noi, Vietnam.
authors.forename: Khanh
authors.initials: K
authors.lastname: Tran Pham
authors.affiliation: Thai Binh University of Medicine and Pharmacy , 373 Ly Bon Street, Thai Binh, Vietnam.
authors.forename: Khai
authors.initials: K
authors.lastname: Ngoc Pham
authors.affiliation: Nha Trang Pasteur Institute , 8-10 Tran Phu, Xuong Huan Ward, Nha Trang City, Vietnam.
authors.forename: Chien
authors.initials: C
authors.lastname: Trong Bui
authors.affiliation: Nha Trang Pasteur Institute , 8-10 Tran Phu, Xuong Huan Ward, Nha Trang City, Vietnam.
authors.forename: Mai
authors.initials: M
authors.lastname: Quang Vien
authors.affiliation: Institute of Public Health, Ho Chi Minh City , 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
authors.forename: Ninh
authors.initials: N
authors.lastname: Hoang Le
authors.affiliation: Institute of Public Health, Ho Chi Minh City , 159 Hung Phu, District 8, Ward 8, Ho Chi Minh City, Vietnam.
authors.forename: Chinh
authors.initials: C
authors.lastname: Van Dang
authors.affiliation: Graduate School of Pharmaceutical Sciences, Osaka University , 1-6 Yamadaoka, Suita, Osaka 565-0871, Japan.|Global Collaboration Center, Osaka University , 2-7 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Hirata
authors.affiliation: Osaka Prefectural Institute of Public Health , 1-3-69 Nakamichi, Higashinari-ku, Osaka 537-0025, Japan.|Global Collaboration Center, Osaka University , 2-7 Yamadaoka, Suita, Osaka 565-0871, Japan.
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Yamamoto
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000032:analysis*; D004350:Drug Residues / Q000032:analysis*; D005506:Food Contamination / Q000032:analysis*; D033541:Palaemonidae / Q000737:chemistry*; D012423:Rural Health; D012758:Shellfish / Q000032:analysis*; D053719:Tandem Mass Spectrometry; D014744:Vietnam; D014874:Water Pollutants, Chemical / Q000032:analysis
chemical_list: D000900:Anti-Bacterial Agents; D014874:Water Pollutants, Chemical
keywords: LC-MS/MS; Vietnam; antibiotic residue; aquaculture; ciprofloxacin; enrofloxacin; fish; shrimp; sulfamethazine; trimethoprim