title: SEQUELAE OF PATIENTS TREATED FOR PULMONARY TUBERCULOSIS IN CHEST CLINIC, TIKUR ANBESSA SPECIALIZED HOSPITAL (TASH), ADDIS ABABA, ETHIOPIA.
abstract: BACKGROUND
  Pulmonary tuberculosis (PTB) is one of the most common infectious diseases worldwide, and contributes significantly to morbidity and mortality in developing countries. Despite availability of effective treatment, a significant number of patients suffer from permanent lung damage, which predisposes patients to numerous pulmonary complications.
  
  
  OBJECTIVE
  To assess chronic sequelae of patients treated for PTB in a chest clinic at Tikur Anbessa Hospital.
  
  
  METHODS
  This was a retrospective, cross-sectional analysis of patients registered in a clinical database at the chest clinic of Tikur Anbessa specialized Hospital between January and December 2013. Patients with a history of pulmonary tuberculosis treatment were identified and included in the analysis.
  
  
  RESULTS
  Among all patients having follow-up at the chest clinic of TASH during the study period, 134 (18.5%) presented with chronic pulmonary complications of TB. Seventy two patients (54%) were male, and the mean and median ages were 40 and 37 years, respectively. Of the study population, 83 (61.9%) patients had clinically significant parenchymal scarring and fibrosis, 40 (29.9%) had bronchiectasis, 5(3.7%) had Aspergilloma, 4(3%) had granuloma/calcification, one patient (0.7%) had pleural thickening, and one patient (0.7%) underwent pneumonectomy during the study period.
  
  
  CONCLUSIONS
  Fibrosis and bronchiectasis were the most common pulmonary complications of tuberculosis among patients encountered at the TASH chest clinic during the study period. This demonstrates the impact of pulmonary tuberculosis is beyond management of active disease.
authors.forename: Amsalu Bekele
authors.initials: AB
authors.lastname: Binegdie
authors.forename: Madhavi
authors.initials: M
authors.lastname: Parekh
authors.forename: Tola Bayisa
authors.initials: TB
authors.lastname: Tolessa
authors.forename: Fahmi Oumer
authors.initials: FO
authors.lastname: Ahmed
authors.forename: Charles Bruce
authors.initials: CB
authors.lastname: Sherman
authors.forename: Jane Charter
authors.initials: JC
authors.lastname: Ethel
authors.forename: Neil W
authors.initials: NW
authors.lastname: Schluger
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001987:Bronchiectasis; D002648:Child; D003430:Cross-Sectional Studies; D005002:Ethiopia / Q000453:epidemiology; D005260:Female; D006782:Hospitals, Special; D006801:Humans; D008297:Male; D008875:Middle Aged; D011658:Pulmonary Fibrosis; D012189:Retrospective Studies; D014397:Tuberculosis, Pulmonary / Q000150:complications* / Q000453:epidemiology*; D055815:Young Adult