title: The effect of butyric acid with autogenous omental graft on healing of experimental Achilles tendon injury in rabbits.
abstract: In this study, the role of local injection of butyric acid (BA) with autogenous omental graft was evaluated in healing of experimental Achilles tendon injury in rabbits. Nine adult male New Zealand rabbits were anesthetized and a partial thickness tenotomy was created on both hindlimbs. In treated group, omental graft was secured in place using BA soaked polygalactin 910 suture. In control group, the graft was sutured without BA. Butyric acid and normal saline were injected daily to treatment and control groups for three days, respectively. Based on the findings, on day 15 after injury, the tendon sections showed that healing rate in BA treated group was higher than that in control group. Furthermore, at days 28 and 45, comparison between BA treated and control groups demonstrated that BA increased the healing rate but with no significance. In summary, results of this study show that application of BA with autogenous omental graft can improve healing process of damaged Achilles tendon.
authors.affiliation: Ph.D. Student in Surgery, Department of Clinical Sciences, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran;
authors.forename: S
authors.initials: S
authors.lastname: Jahani
authors.affiliation: Department of Clinical Sciences, Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar, Iran;
authors.forename: H R
authors.initials: HR
authors.lastname: Moslemi
authors.affiliation: Department of Clinical Sciences, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran;
authors.forename: M M
authors.initials: MM
authors.lastname: Dehghan
authors.affiliation: Department of Anatomy and Pathology, Faculty of Medicine, Shahed University, Tehran, Iran;
authors.forename: R
authors.initials: R
authors.lastname: Sedaghat
authors.affiliation: Rastegar Central Laboratory, Faculty of Veterinary Medicine, University of Tehran, Tehran, Iran;
authors.forename: R
authors.initials: R
authors.lastname: Mazaheri Nezhad
authors.affiliation: Graduated from Faculty of Veterinary Medicine, Garmsar Branch, Islamic Azad University, Garmsar, Iran.
authors.forename: D
authors.initials: D
authors.lastname: Rezaee Moghaddam
keywords: Achilles tendon; Butyric acid; Omental graft