title: Administering the Sarcoidosis Health Questionnaire to sarcoidosis patients in Serbia.
abstract: OBJECTIVE
  The aim of this study was to use a Serbian-language version of the disease-specific, self-report Sarcoidosis Health Questionnaire (SHQ), which was designed and originally validated in the United States, to assess health status in sarcoidosis patients in Serbia, as well as validating the instrument for use in the country.
  
  
  METHODS
  This was a cross-sectional study of 346 patients with biopsy-confirmed sarcoidosis. To evaluate the health status of the patients, we used the SHQ, which was translated into Serbian for the purposes of this study. We compared SHQ scores by patient gender and age, as well as by disease duration and treatment. Lower SHQ scores indicate poorer health status.
  
  
  RESULTS
  The SHQ scores demonstrated differences in health status among subgroups of the sarcoidosis patients evaluated. Health status was found to be significantly poorer among female patients and older patients, as well as among those with chronic sarcoidosis or extrapulmonary manifestations of the disease. Monotherapy with methotrexate was found to be associated with better health status than was monotherapy with prednisone or combination therapy with prednisone and methotrexate.
  
  
  CONCLUSIONS
  The SHQ is a reliable, disease-specific, self-report instrument. Although originally designed for use in the United States, the SHQ could be a useful tool for the assessment of health status in various non-English-speaking populations of sarcoidosis patients.
authors.affiliation: Clinical Center of Serbia, Belgrade, Serbia.
authors.forename: Violeta
authors.initials: V
authors.lastname: Mihailović-Vučinić
authors.affiliation: Pharmacovigilance Department, Pharmaceutical Product Development Serbia, Belgrade, Serbia.
authors.forename: Branislav
authors.initials: B
authors.lastname: Gvozdenović
authors.affiliation: School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Mihailo
authors.initials: M
authors.lastname: Stjepanović
authors.affiliation: Education Department, Health Center Valjevo, Valjevo, Serbia.
authors.forename: Mira
authors.initials: M
authors.lastname: Vuković
authors.affiliation: School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Ljiljana
authors.initials: L
authors.lastname: Marković-Denić
authors.affiliation: Dr. Dragomir Karajovic Occupational Health Institute of Serbia, Belgrade, Serbia.
authors.forename: Aleksandar
authors.initials: A
authors.lastname: Milovanović
authors.affiliation: School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Jelica
authors.initials: J
authors.lastname: Videnović-Ivanov
authors.affiliation: Clinical Center of Serbia, Belgrade, Serbia.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Žugić
authors.affiliation: Clinical Center of Serbia, Belgrade, Serbia.
authors.forename: Vesna
authors.initials: V
authors.lastname: Škodrić-Trifunović
authors.affiliation: School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Snežana
authors.initials: S
authors.lastname: Filipović
authors.affiliation: School of Medicine, University of Belgrade, Belgrade, Serbia.
authors.forename: Maja
authors.initials: M
authors.lastname: Omčikus
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D003430:Cross-Sectional Studies; D005260:Female; D006304:Health Status; D006801:Humans; D007802:Language; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D015203:Reproducibility of Results; D012507:Sarcoidosis / Q000503:physiopathology* / Q000523:psychology / Q000628:therapy; D057566:Self Report / Q000592:standards*; D055771:Serbia; D018709:Statistics, Nonparametric; D011795:Surveys and Questionnaires; D014177:Translations