title: Magnetic nanoparticles modified with quaternarized N-halamine based polymer and their antibacterial properties.
abstract: We present a simple and facile approach for preparing antibacterial magnetic nanoparticles, which were modified with quaternarized N-halamine based cationic polymer (CPQN). The CPQN functionalized magnetic nanoparticles (MNPs-CPQN) were characterized by X-ray photoelectron spectra, Fourier transform infrared spectroscopy, transmission electron microscopy, scanning electron microscopy, and thermogravimetric analysis. Antibacterial properties were investigated with Gram positive bacteria S. aureus and Gram negative bacteria E. coli. Antibacterial assessment showed that the MNPs-CPQN could eliminate nearly 100% of S. aureus and 99.9% of E. coli (10(7-8) CFU/mg nanoparticles) in 5 min, while the bactericide rate of quaternized N-halamine precursor based cationic polymer coated magnetic nanoparticles (MNPs-CPQNP) were 99.6 and 95.2%, respectively. The prepared nanoparticles exhibited a good response to an external magnetic field and had a saturation magnetization of 36.6 emu g(-1). On the basis of their excellent antibacterial properties and magnetic responsiveness, the MNPs-CPQN would be a promising antibacterial material for water disinfection.
authors.affiliation: a College of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , China.
authors.forename: Xiaoqin
authors.initials: X
authors.lastname: Chen
authors.affiliation: a College of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , China.
authors.forename: Bojian
authors.initials: B
authors.lastname: Hu
authors.affiliation: a College of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Xiang
authors.affiliation: a College of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , China.
authors.forename: Chunyan
authors.initials: C
authors.lastname: Yong
authors.affiliation: a College of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , China.
authors.forename: Zuliang
authors.initials: Z
authors.lastname: Liu
authors.affiliation: a College of Chemical Engineering , Nanjing University of Science and Technology , Nanjing , China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Xing
mesh_terms: D000588:Amines / Q000737:chemistry*; D000900:Anti-Bacterial Agents / Q000737:chemistry*; D002412:Cations; D002712:Chlorides / Q000737:chemistry*; D004926:Escherichia coli / Q000187:drug effects; D005290:Ferric Compounds / Q000737:chemistry*; D005296:Ferrous Compounds / Q000737:chemistry*; D006801:Humans; D053768:Metal Nanoparticles / Q000737:chemistry*; D008826:Microbial Sensitivity Tests; D010316:Particle Size; D058105:Polymerization; D011109:Polymethacrylic Acids / Q000737:chemistry*; D011726:Pyridinium Compounds / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects; D013499:Surface Properties
chemical_list: D000588:Amines; D000900:Anti-Bacterial Agents; D002412:Cations; D002712:Chlorides; D005290:Ferric Compounds; D005296:Ferrous Compounds; D011109:Polymethacrylic Acids; D011726:Pyridinium Compounds; C030613:polymethacrylic acid; C029451:ferrous chloride; C024555:ferric chloride
keywords: Antibacterial; N-halamine; cationic polymer; magnetic nanoparticles; quaternary ammonium salts