title: Infection of the central nervous system with dengue virus 3 genotype I causing neurological manifestations in Brazil.
abstract: A case of dengue virus 3 (DENV-3) genotype I infection with neurological manifestations occurred in Belo Horizonte, Minas Gerais in October 2012. The serotype was detected by PCR, and the genotype was assessed by sequencing and phylogenetic analysis of the C-prM region. The virus causing neurological manifestations clustered with other sequences of DENV-3 genotype I. Because neurological manifestations of DENV are possibly misdiagnosed in Brazil, this study serves as an alert of the importance of DENV diagnoses in CNS infections.
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Danilo Bretas de
authors.initials: DB
authors.lastname: Oliveira
authors.affiliation: Hospital Risoleta Tolentino Neves, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Guilherme
authors.initials: G
authors.lastname: Machado
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Gabriel Magno de Freitas
authors.initials: GM
authors.lastname: Almeida
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Paulo César Peregrino
authors.initials: PC
authors.lastname: Ferreira
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Cláudio Antônio
authors.initials: CA
authors.lastname: Bonjardim
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Giliane de Souza
authors.initials: Gde S
authors.lastname: Trindade
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Jônatas Santos
authors.initials: JS
authors.lastname: Abrahão
authors.affiliation: Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
authors.forename: Erna Geessien
authors.initials: EG
authors.lastname: Kroon
mesh_terms: D020805:Central Nervous System Viral Diseases / Q000150:complications / Q000821:virology*; D003715:Dengue / Q000150:complications / Q000821:virology*; D003716:Dengue Virus / Q000235:genetics*; D005260:Female; D005838:Genotype; D006801:Humans; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D055815:Young Adult
chemical_list: D012367:RNA, Viral