title: Central nervous system vasculitis in pediatric microscopic polyangiitis.
abstract: <p>Microscopic polyangiitis is a small vessel vasculitis, associated with myeloperoxidaseantineutrophil cytoplasmic antibody. It rarely occurs in children. Central nervous system involvement in pediatric microscopic polyangiitis is not a well known entity with perhaps only five cases till date. We hereby present a 14-year-old girl with arthralgia, seizure, leukocytoclastic vasculitis, interstitial lung disease secondary to recurrent pulmonary hemorrhage, pauci-immune glomerulonephritis and high titers of MPO-ANCA, hence diagnostic of microscopic polyangiitis. Magnetic resonance imaging of brain showed diffuse parenchymal involvement which resolved at six months with development of new foci of microhemorrhages in different stages of evolution, reminiscent of vasculitis.</p>.
authors.affiliation: King George's Medical University, Lucknow.
authors.forename: Danveer
authors.initials: D
authors.lastname: Bhadu
authors.affiliation: King George's Medical University, Lucknow.
authors.forename: Puneet
authors.initials: P
authors.lastname: Kumar
authors.affiliation: Dr. RML Institute of Medical Sciences, Lucknow, India.
authors.forename: Kiran Preet
authors.initials: KP
authors.lastname: Malhotra
authors.affiliation: King George's Medical University, Lucknow.
authors.forename: Aarti
authors.initials: A
authors.lastname: Sharma
authors.affiliation: King George's Medical University, Lucknow.
authors.forename: Meha
authors.initials: M
authors.lastname: Sharma
authors.affiliation: King George's Medical University, Lucknow.
authors.forename: Durgesh
authors.initials: D
authors.lastname: Srivastava
mesh_terms: D000293:Adolescent; D005260:Female; D006801:Humans; D055953:Microscopic Polyangiitis / Q000150:complications*; D020293:Vasculitis, Central Nervous System / Q000209:etiology*