title: Modeling and Simulation of 4D PET-CT and PET-MR Images.
abstract: The driving force in the research and development of new hybrid PET-CT/MR imaging scanners is the production of images with optimum quality, accuracy, and resolution. However, the acquisition process is limited by several factors. Key issues are the respiratory and cardiac motion artifacts that occur during an imaging session. In this article the necessary tools for modeling and simulation of realistic high-resolution four-dimensional PET-CT and PET-MR imaging data are described. Beyond the need for four-dimensional simulations, accurate modeling of the acquisition process can be included within the reconstruction algorithms assisting in the improvement of image quality and accuracy of estimation of physiologic parameters from four-dimensional hybrid PET imaging.
authors.affiliation: Division of Imaging Sciences and Biomedical Engineering, Department of Biomedical Engineering, King's College London, King's Health Partners, St. Thomas' Hospital, London SE1 7EH, UK. Electronic address: charalampos.tsoumpas@kcl.ac.uk.
authors.forename: Charalampos
authors.initials: C
authors.lastname: Tsoumpas
authors.affiliation: Department of Biomedical Technology, Biomedical Research Foundation of the Academy of Athens, Soranou Efessiou 4, Athens 11527, Greece.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Gaitanis