title: Occult Adenoma in Patent Vitellointestinal Duct Presenting as an Umbilical Fistula: Cause for Concern?
abstract: BACKGROUND
  Prevalence of vitellointestinal duct anomalies varies from 2-4%. Though a completely patent vitellointestinal duct is a common symptomatic embryological defect with a prevalence of 0.0063-0.067%, other vitellointestinal abnormalities are rarely reported. Ours is the first case to describe histopathological features of an umbilical fistula harboring an occult tubular adenoma.
  
  
  METHODS
  We report a case of one-month old child, presenting with umbilical fistula for which excision and ileal anastomosis was performed. Routine histopathologic examination revealed an occult tubular adenoma in tip of the fistula.
  
  
  CONCLUSIONS
  Adenoma arising in an umbilical fistula at such an early stage of infancy has never been reported before. Detection of occult adenoma warrants screening GI endoscopy, genetic testing for syndromic gastrointestinal adenomatosis and carcinomas and lifelong surveillance. Our case highlights the importance of routine histopathologic examination in detection of occult premalignant lesions as it significantly affects the patient management and prognosis.
authors.affiliation: a Department of Pathology , Vardhman Mahavir Medical College & Safdarjung Hospital , New Delhi , India.
authors.forename: Himani
authors.initials: H
authors.lastname: Bhankar
authors.affiliation: a Department of Pathology , Vardhman Mahavir Medical College & Safdarjung Hospital , New Delhi , India.
authors.forename: Surbhi
authors.initials: S
authors.lastname: Goyal
authors.affiliation: a Department of Pathology , Vardhman Mahavir Medical College & Safdarjung Hospital , New Delhi , India.
authors.forename: Sufian
authors.initials: S
authors.lastname: Zaheer
authors.affiliation: b Department of Paediatric Surgery , Vardhman Mahavir Medical College & Safdarjung Hospital , New Delhi , India.
authors.forename: Nidhi
authors.initials: N
authors.lastname: Sugandhi
authors.affiliation: a Department of Pathology , Vardhman Mahavir Medical College & Safdarjung Hospital , New Delhi , India.
authors.forename: Ashish Kumar
authors.initials: AK
authors.lastname: Mandal
mesh_terms: D000236:Adenoma / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D007412:Intestinal Fistula / Q000473:pathology*; D007422:Intestines / Q000002:abnormalities; D014472:Umbilicus / Q000473:pathology*; D014816:Vitelline Duct / Q000002:abnormalities*
keywords: Adenoma; patent vitellointestinal duct; umbilical fistula