title: Preserved brain metabolic activity at the age of 96 years.
abstract: Loss of brain tissue becomes notable to cerebral magnetic resonance imaging (MRI) at age 30 years, and progresses more rapidly from mid 60s. The incidence of dementia increases exponentially with age, and is all too frequent in the oldest old (≥ 90 years of age), the fastest growing age group in many countries. However, brain pathology and cognitive decline are not inevitable, even at extremely old age (den Dunnen et al., 2008).
authors.affiliation: Department of Radiology and Nuclear Medicine,University Hospital Magdeburg,Magdeburg,Germany.
authors.forename: Ivayla
authors.initials: I
authors.lastname: Apostolova
authors.affiliation: Department of Nuclear Medicine,Charité - Universitätsmedizin,Berlin,Germany.
authors.forename: Catharina
authors.initials: C
authors.lastname: Lange
authors.affiliation: jung diagnostics GmbH,Hamburg,Germany.
authors.forename: Lothar
authors.initials: L
authors.lastname: Spies
authors.affiliation: Bernstein Center for Computational Neuroscience Berlin,Charité - Universitätsmedizin,Berlin,Germany.
authors.forename: Kerstin
authors.initials: K
authors.lastname: Ritter
authors.affiliation: Evangelisches Geriatriezentrum Berlin,Berlin,Germany.
authors.forename: Anja
authors.initials: A
authors.lastname: Mäurer
authors.affiliation: Evangelisches Geriatriezentrum Berlin,Berlin,Germany.
authors.forename: Joachim
authors.initials: J
authors.lastname: Seybold
authors.affiliation: Center for Stroke Research Berlin,Charité - Universitätsmedizin,Berlin,Germany.
authors.forename: Jochen B
authors.initials: JB
authors.lastname: Fiebach
authors.affiliation: Lipid Clinic at the Interdisciplinary Metabolism Center,Charité - Universitätsmedizin,Berlin,Germany.
authors.forename: Elisabeth
authors.initials: E
authors.lastname: Steinhagen-Thiessen
authors.affiliation: Department of Nuclear Medicine,Charité - Universitätsmedizin,Berlin,Germany.
authors.forename: Ralph
authors.initials: R
authors.lastname: Buchert
mesh_terms: D000369:Aged, 80 and over; D001921:Brain / Q000000981:diagnostic imaging* / Q000378:metabolism* / Q000473:pathology; D003072:Cognition Disorders / Q000175:diagnosis*; D003704:Dementia / Q000175:diagnosis*; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D049268:Positron-Emission Tomography
chemical_list: D019788:Fluorodeoxyglucose F18