title: Comparative analysis of prophage-like elements in Helicobacter sp. genomes.
abstract: Prophages are regarded as one of the factors underlying bacterial virulence, genomic diversification, and fitness, and are ubiquitous in bacterial genomes. Information on Helicobacter sp. prophages remains scarce. In this study, sixteen prophages were identified and analyzed in detail. Eight of them are described for the first time. Based on a comparative genomic analysis, these sixteen prophages can be classified into four different clusters. Phylogenetic relationships of Cluster A Helicobacter prophages were investigated. Furthermore, genomes of Helicobacter prophages from Clusters B, C, and D were analyzed. Interestingly, some putative antibiotic resistance proteins and virulence factors were associated with Helicobacter prophages.
authors.affiliation: School of Biological Science and Technology, University of Jinan , Jinan , China.
authors.forename: Xiangyu
authors.initials: X
authors.lastname: Fan
authors.affiliation: School of Biological Science and Technology, University of Jinan , Jinan , China.
authors.forename: Yumei
authors.initials: Y
authors.lastname: Li
authors.affiliation: School of Biological Science and Technology, University of Jinan , Jinan , China.
authors.forename: Rong
authors.initials: R
authors.lastname: He
authors.affiliation: School of Biological Science and Technology, University of Jinan , Jinan , China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Li
authors.affiliation: School of Biological Science and Technology, University of Jinan , Jinan , China.
authors.forename: Wenxing
authors.initials: W
authors.lastname: He
keywords: Comparative genomics; Helicobacter; Phylogeny; Prophage