title: Local recurrent vaginal aggressive angiomyxoma misdiagnosed as cellular angiomyofibroblastoma: A case report.
abstract: Aggressive angiomyxoma (AAM) and angiomyofibroblastoma (AMFB) are two rare types of mesenchymal tumors with overlapping clinicopathological features. In certain cases, the differential diagnosis between the two tumors is difficult even for experienced pathologists. The present study reported the case of a well-circumscribed soft tissue mass on the anterior wall of the vagina in a 25-year-old woman. The mass was initially removed without disturbance to the adjacent tissues. The histopathological features included spindle cells in inconspicuous myxoid stroma and a well-demarcated mass without evidence of invasion, which prompted the initial diagnosis of AMFB. After 2 years, a mass returned in the same area and a wide tumor excision was performed. The histopathological examination confirmed the final diagnosis of AAM upon review.
authors.affiliation: Department of Gynecology, Women's Hospital, School of Medicine Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China.
authors.forename: Yin-Feng
authors.initials: YF
authors.lastname: Wang
authors.affiliation: Department of Gynecology, Women's Hospital, School of Medicine Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China.
authors.forename: Hong-Lang
authors.initials: HL
authors.lastname: Qian
authors.affiliation: Department of Gynecology, Women's Hospital, School of Medicine Zhejiang University, Hangzhou, Zhejiang 310006, P.R. China.
authors.forename: Hang-Mei
authors.initials: HM
authors.lastname: Jin
keywords: aggressive angiomyxoma; cellular angiomyofibroblastoma; misdiagnosis; recurrence