title: Double phase treatment with flashlamp-pumped pulsed-dye laser and long pulsed Nd:YAG laser for resistant port wine stains in adults. Preliminary reports.
abstract: BACKGROUND
  Flashlamp-pumped pulsed (FLPP) dye laser still represents the standard treatment for the majority of port wine stains (PWSs), but the results on thick PWSs remain unpredictable, and many of these lesions fail to completely respond. Our aim was to report on the results obtained on unresponsive PWSs to standard laser treatments, by using a double phase laser treatment strategy using two laser passes in the same session.
  
  
  METHODS
  Eleven adult patients with facial PWS resistant to dye laser were enrolled. Laser sessions were scheduled every 8 weeks, and each of them consisting of two laser passes. In phase one, two different laser wavelengths (595 nm and 1064 nm) were delivered consecutively to each affected area. In the second phase, the PWS was treated using a pulse stacking technique with the 1064 nm Nd:YAG.
  
  
  RESULTS
  One patient was lost to follow-up. Among the remaining ten, 5 (50%) patients showed an excellent improvement (>75%), 3 (30%) patients showed a good improvement (51-75%), and 2 (20%) patients had no or minimal improvement (0-25%).
  
  
  CONCLUSIONS
  Our results suggest that the combination of different wavelengths in the same session can be helpful for PWSs resistant to standard laser treatments. However, in most patients two treatment phases were necessary.
authors.affiliation: Istituto di Chirurgia e Laserchirurgia in Dermatologia (I.C.L.I.D.), Milan, Italy - info@laserforum.it.
authors.forename: Pier L
authors.initials: PL
authors.lastname: Bencini
authors.forename: Athanasia
authors.initials: A
authors.lastname: Tourlaki
authors.forename: Matteo
authors.initials: M
authors.lastname: Tretti Clementoni
authors.forename: Luigi
authors.initials: L
authors.lastname: Naldi
authors.forename: Michela
authors.initials: M
authors.lastname: Galimberti
mesh_terms: D000328:Adult; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D053844:Lasers, Solid-State / Q000627:therapeutic use*; D028022:Low-Level Light Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D019339:Port-Wine Stain / Q000532:radiotherapy*; D011446:Prospective Studies; D016896:Treatment Outcome