title: Patient anxiety on the use of one step nucleic acid amplification (OSNA) during breast cancer surgery.
abstract: BACKGROUND
  Assessment of the sentinel lymph node biopsy (SLNB) is used to stage the axilla in patients with breast cancer. There are a variety of methods to assess metastatic disease within the SLN. One-step nucleic acid amplification (OSNA) has a high sensitivity for detecting metastatic disease within the SLN and avoids the use of staged axillary surgery. However there remains a paucity of data within the literature on the psychological effects upon patients with the use of OSNA.
  
  
  METHODS
  All patients undergoing breast surgery (breast-conserving surgery or mastectomy) and assessment of the SLNB with OSNA from December 2011 to June 2012 were included in the study. A questionnaire was sent to patient within four weeks of surgery to assess their understanding and satisfaction with the OSNA procedure.
  
  
  RESULTS
  60 patients responded to the questionnaire (83% response rate). All patients were female with a mean age of 63 years (range 38-71 years). 19 patients had positive SLNB as assessed by OSNA and all had ALND. 15 patients expressed pre-operative anxiety about having OSNA although 97% stated that they would be happy to undergo the same procedure again.
  
  
  CONCLUSIONS
  Our study has identified the anxiety points that patients experience with OSNA based management and this will allow improved direct emotional support and provision of information.
authors.forename: Ruvinder Kaur
authors.initials: RK
authors.lastname: Athwal
authors.forename: Dayalan
authors.initials: D
authors.lastname: Clarke
authors.forename: Simon
authors.initials: S
authors.lastname: Harries
authors.forename: Lucie
authors.initials: L
authors.lastname: Jones
mesh_terms: D000328:Adult; D000368:Aged; D001007:Anxiety / Q000523:psychology*; D001943:Breast Neoplasms / Q000235:genetics / Q000473:pathology / Q000523:psychology* / Q000601:surgery; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008408:Mastectomy; D015412:Mastectomy, Segmental; D008875:Middle Aged; D009367:Neoplasm Staging / Q000379:methods / Q000523:psychology; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D017060:Patient Satisfaction; D000071036:Sentinel Lymph Node / Q000378:metabolism* / Q000473:pathology; D021701:Sentinel Lymph Node Biopsy; D011795:Surveys and Questionnaires
keywords: Breast cancer; anexity; sentinel lymph node biopsy