title: Accuracy, Precision, Sensitivity, and Specificity of Noninvasive ICP Absolute Value Measurements.
abstract: An innovative absolute intracranial pressure (ICP) value measurement method has been validated by multicenter comparative clinical studies. The method is based on two-depth transcranial Doppler (TCD) technology and uses intracranial and extracranial segments of the ophthalmic artery as pressure sensors. The ophthalmic artery is used as a natural pair of "scales" that compares ICP with controlled pressure Pe, which is externally applied to the orbit. To balance the scales, ICP = Pe a special two-depth TCD device was used as a pressure balance indicator. The proposed method is the only noninvasive ICP measurement method that does not need patient-specific calibration.
authors.affiliation: Health Telematics Science Institute, Kaunas University of Technology, Kaunas, Lithuania.
authors.forename: Solventa
authors.initials: S
authors.lastname: Krakauskaite
authors.affiliation: Health Telematics Science Institute, Kaunas University of Technology, Kaunas, Lithuania.
authors.forename: Vytautas
authors.initials: V
authors.lastname: Petkus
authors.affiliation: Health Telematics Science Institute, Kaunas University of Technology, Kaunas, Lithuania.
authors.forename: Laimonas
authors.initials: L
authors.lastname: Bartusis
authors.affiliation: Health Telematics Science Institute, Kaunas University of Technology, Kaunas, Lithuania.
authors.forename: Rolandas
authors.initials: R
authors.lastname: Zakelis
authors.affiliation: Health Telematics Science Institute, Kaunas University of Technology, Kaunas, Lithuania.
authors.forename: Romanas
authors.initials: R
authors.lastname: Chomskis
authors.affiliation: Faculty of Medicine, Clinic of Neurology and Neurosurgery, Vilnius University, Vilnius, Lithuania.|Department of Neurology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Aidanas
authors.initials: A
authors.lastname: Preiksaitis
authors.affiliation: Health Telematics Science Institute, Kaunas University of Technology, Kaunas, Lithuania. telematics@ktu.lt.
authors.forename: Arminas
authors.initials: A
authors.lastname: Ragauskas
authors.affiliation: Department of Neurology, Kaunas Clinics, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Vaidas
authors.initials: V
authors.lastname: Matijosaitis
authors.affiliation: Department of Neurology, Kaunas Clinics, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Kestutis
authors.initials: K
authors.lastname: Petrikonis
authors.affiliation: Department of Neurology, Kaunas Clinics, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Daiva
authors.initials: D
authors.lastname: Rastenyte
mesh_terms: D000070642:Brain Injuries, Traumatic / Q000150:complications / Q000000981:diagnostic imaging; D020275:Guillain-Barre Syndrome / Q000000981:diagnostic imaging; D018475:Head-Down Tilt; D006801:Humans; D006849:Hydrocephalus / Q000150:complications / Q000000981:diagnostic imaging; D019586:Intracranial Hypertension / Q000000981:diagnostic imaging* / Q000209:etiology; D007427:Intracranial Pressure; D008991:Monitoring, Physiologic; D009103:Multiple Sclerosis / Q000000981:diagnostic imaging; D009880:Ophthalmic Artery / Q000000981:diagnostic imaging*; D011115:Polyneuropathies / Q000000981:diagnostic imaging; D011446:Prospective Studies; D012372:ROC Curve; D012044:Regression Analysis; D012680:Sensitivity and Specificity; D017585:Ultrasonography, Doppler, Transcranial / Q000379:methods
keywords: Bland–Altman analysis; Noninvasive ICP absolute value method; ROC analysis; Regression analysis; Two-depth transcranial Doppler meter