title: The Role of PET/CT in Advanced Malignant Melanoma.
abstract: Positron emission tomography/computed tomography (PET/CT) with fluorodeoxyglucose demonstrates a high sensitivity and specificity for detecting both locoregional and distant metastases in patients presenting with AJCC stages III and IV disease. PET/CT also plays an important role in the detection of recurrence particularly in high-risk group patients, and this should be the modality of choice in investigating patients for suspected recurrence. The role of PET/CT in response assessment and follow-up still has to be defined, and cost-effectiveness analysis is required to strengthen its role.
authors.affiliation: Department of Nuclear Medicine, Imperial College Healthcare Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.
authors.forename: Imene
authors.initials: I
authors.lastname: Zerizer
authors.affiliation: Department of Nuclear Medicine, Imperial College Healthcare Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.
authors.forename: Brian Ng
authors.initials: BN
authors.lastname: Cheng Hin
authors.affiliation: Department of Nuclear Medicine, Imperial College Healthcare Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.
authors.forename: Wing Yan
authors.initials: WY
authors.lastname: Mok
authors.affiliation: Department of Nuclear Medicine, Imperial College Healthcare Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.
authors.forename: Sameer
authors.initials: S
authors.lastname: Khan
authors.affiliation: Department of Nuclear Medicine, PET/CT Centre, Santa Maria della Misericordia Hospital, Viale Tre Martiri 140, 45100 Rovigo, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Rubello
authors.affiliation: Department of Nuclear Medicine, Imperial College Healthcare Trust, Hammersmith Hospital, Du Cane Road, London W12 0HS, UK.
authors.forename: Adil
authors.initials: A
authors.lastname: Al-Nahhas