title: Recurrence patterns of mucose-associated lymphoid tissue lymphoma after definitive radiation treatment: A single center experience.
abstract: OBJECTIVE
  To evaluate the treatment outcomes in non-gastric and non-nodal mucose-associated lymphoid tissue (MALT) lymphoma patients treated by definitive radiation therapy (RT).
  
  
  METHODS
  A total of 134 patients were analyzed. The RT dose was 30.6 or 36 Gy.
  
  
  RESULTS
  The median follow-up duration for all patients was 51.1 months (range, 3.0-132.4 months). Among the 88 orbital MALT lymphoma patients, 12 had disease recurrence. There were 23 head and neck tumor patients. Two patients experienced relapse, all at out-of-field locations. Gastrointestinal MALT lymphoma was diagnosed in 13 patients, and three showed local (n = 1), distant (n = 1), or local/distant (n = 1) relapse.
  
  
  CONCLUSIONS
  RT alone is highly effective in achieving local control and long-term survival in localized MALT lymphoma. In orbital MALT, excellent local control is achieved, and relapse is predominantly observed in the contralateral eye. Other head and neck lymphomas are also well controlled.
authors.affiliation: a Department of Radiation Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Ji Hyeon
authors.initials: JH
authors.lastname: Joo
authors.affiliation: a Department of Radiation Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Sang-Wook
authors.initials: SW
authors.lastname: Lee
authors.affiliation: b Department of Pathology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Jooryung
authors.initials: J
authors.lastname: Huh
authors.affiliation: c Department of Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Cheolwon
authors.initials: C
authors.lastname: Suh
authors.affiliation: c Department of Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Dok Hyun
authors.initials: DH
authors.lastname: Yoon
authors.affiliation: a Department of Radiation Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Seung Do
authors.initials: SD
authors.lastname: Ahn
authors.affiliation: a Department of Radiation Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Eun Kyung
authors.initials: EK
authors.lastname: Choi
authors.affiliation: a Department of Radiation Oncology, Asan Medical Center , University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Jong Hoon
authors.initials: JH
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D005260:Female; D006801:Humans; D018442:Lymphoma, B-Cell, Marginal Zone / Q000473:pathology* / Q000532:radiotherapy*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000473:pathology*; D011379:Prognosis; D011879:Radiotherapy Dosage; D016896:Treatment Outcome; D055815:Young Adult
keywords: Lymphoma; MALT; Radiotherapy; Recurrences