title: [CHANGES OF CAROTID AND VERTEBRAL ARTERIES IN PATENTS WITH ARTERIAL HYPERTENSION AND HEPATOBILIARY PATHOLOGY].
abstract: The study included 1172 patients (410 men and 762 women) at the mean age of 60.3 ± 10.4 years with grade I-II (stage I-II) arterial hypertension (AH) admitted to the clinic of Institute of Experimental Medicine. The patients were divided into 2 groups based on the results of clinical and laboratory diagnostics. Group 1 (n = 525) included patients with AH and hepatobiliary system (HBS) diseases, group 2 (n = 647) patients with AH without HBS diseases. The patients group 1 had a thicker intima-media complex of carotid arteries, higher peak systolic bloodflow rate in the internal and vertebral carotid arteries, more pronounced coiling of internal carotid arteries than patients of group 2. Patients with AH and HBS diseases exhibited correlation between bloodflow rate in external carotid arteries and atherogenicity coefficient. Duplex scanning of neck vessels of in patients with AH without HBS diseases revealed peculiar changes of the intima-media thickness and hemodynamically significant changes of the blood flow in the internal carotid arteries that may be of prognostic value in this nosological syntropy and require the personified approach to diagnostics, treatment, and prevention of these conditions.
authors.forename: V Ya
authors.initials: VY
authors.lastname: Polyakov
authors.forename: Yu A
authors.initials: YA
authors.lastname: Nikolaev
authors.forename: S V
authors.initials: SV
authors.lastname: Pegova
authors.forename: T R
authors.initials: TR
authors.lastname: Matsievskaya
authors.forename: I V
authors.initials: IV
authors.lastname: Obukhov
mesh_terms: D000368:Aged; D001660:Biliary Tract Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D002339:Carotid Arteries / Q000000981:diagnostic imaging / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D005260:Female; D006439:Hemodynamics; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D008107:Liver Diseases / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D013223:Statistics as Topic; D018616:Ultrasonography, Doppler, Duplex / Q000379:methods; D014711:Vertebral Artery / Q000000981:diagnostic imaging / Q000503:physiopathology