title: Isolated Adrenocorticotropic Hormone or Thyrotropin Deficiency Following Mild Traumatic Brain Injury: Three Cases with Long-Term Follow-Up.
abstract: Few studies have examined the clinical features and long-term outcomes of isolated pituitary hormone deficiencies after traumatic brain injury (TBI). Such deficiencies typically present at time intervals after TBI, especially after mild injuries such as concussions, which makes their diagnosis difficult without careful history taking. It is necessary to improve diagnosis and prevent life threatening or morbid conditions such as those that may occur in deficiencies of adrenocorticotropic hormone (ACTH) or thyroid-stimulating hormone (as known as thyrotropin, TSH), the two most important pituitary hormones in hypopituitarism treatment. Here, we report two cases of isolated ACTH deficiency and one case of isolated TSH deficiency. These patients presented at different time points after concussion and underwent long-term follow-ups.
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.
authors.forename: Cho-Ok
authors.initials: CO
authors.lastname: Baek
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonbuk National University Medical School, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
authors.forename: Yu Ji
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Presbyterian Medical Center, Jeonju, Korea.
authors.forename: Ji Hye
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Division of Endocrinology and Metabolism, Department of Internal Medicine, Chonbuk National University Medical School, Biomedical Research Institute of Chonbuk National University Hospital, Jeonju, Korea.
authors.forename: Ji Hyun
authors.initials: JH
authors.lastname: Park
keywords: Adrenocorticotropic hormone; Brain injuries; Hypopituitarism; Thyrotropin