title: Prevention strategies for blood-borne viruses-in the Era of vaccines, direct acting antivirals and antiretroviral therapy.
abstract: Blood-borne viruses, such as hepatitis B virus, hepatitis C virus, human immunodeficiency virus, and the facultative blood-borne hepatitis E virus, are considered a major public health problem given that they are accountable for millions of deaths each year. Treatment options, including effective vaccine design, development of antiviral strategies and the implementation of antiretroviral therapy have improved substantially over the last couple of years and contribute to successful treatment and prevention of these infectious diseases. In this review, we summarise the current knowledge and concepts in prevention of transmission of these blood-borne viruses.
authors.affiliation: Institute for Experimental Virology, Twincore, and Hannover Medical School Hannover, Germany, and Helmholtz Centre for Infection Research, Braunschweig, Germany.|Department of Infectious Diseases and Pathobiology, University of Bern, 3012 Bern, Switzerland, Federal Department of Home Affairs, Institute of Virology and Immunology, 3012 Bern and 3147, Mittelhäusern, Switzerland.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Pfaender
authors.affiliation: Department of Gastroenterology, Hepatology and Endocrinology, Medizinische Hochschule Hannover, Hannover, Germany.|German Center for Infection Research (DZIF) - Hannover-Braunschweig Site.|Institute for Molecular Biology, Medizinische Hochschule Hannover, Hannover, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: von Hahn
authors.affiliation: Institute of Medical Microbiology, University Hospital Essen, Essen, Germany.
authors.forename: Joerg
authors.initials: J
authors.lastname: Steinmann
authors.affiliation: Institute for Virology, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
authors.forename: Sandra
authors.initials: S
authors.lastname: Ciesek
authors.affiliation: Institute for Experimental Virology, Twincore, and Hannover Medical School Hannover, Germany, and Helmholtz Centre for Infection Research, Braunschweig, Germany. eike.steinmann@twincore.de.
authors.forename: Eike
authors.initials: E
authors.lastname: Steinmann
mesh_terms: D000998:Antiviral Agents / Q000627:therapeutic use*; D015658:HIV Infections / Q000517:prevention & control* / Q000628:therapy*; D006525:Hepatitis, Viral, Human / Q000517:prevention & control* / Q000628:therapy*; D006801:Humans; D014765:Viral Vaccines / Q000627:therapeutic use*; D014766:Viremia / Q000517:prevention & control* / Q000628:therapy
chemical_list: D000998:Antiviral Agents; D014765:Viral Vaccines