title: Disseminated Mycobacterium chelonae infection in a patient with T-cell lymphoma.
abstract: Infections with rapidly growing mycobacteria are rare and most often seen in immunocompromised patients. We herein present the case of a 69-year-old man with a T-cell lymphoma treated by chemotherapy and mogamulizumab with a 6-month history of febrile episodes and subcutaneous nodules in both arms and arthritis of metacarpophalangeal joints. Blood cultures and DNA sequencing results demonstrated the growth of Mycobacterium chelonae. The patient was successfully treated with clarithromycin, moxifloxacin, and tobramycin, but died shortly after due to lymphoma progression.
authors.affiliation: Department of Internal Medicine, Zaans Medisch Centrum, Zaandam, The Netherlands. Electronic address: Wvanderwekken@gmail.com.
authors.forename: Lena
authors.initials: L
authors.lastname: van der Wekken
authors.affiliation: Department of Pulmonology and Tuberculosis, Spaarne Ziekenhuis, Hoofddorp, The Netherlands.
authors.forename: Jacobine
authors.initials: J
authors.lastname: Herbrink
authors.affiliation: Department of Internal Medicine, Spaarne Ziekenhuis, Hoofddorp, The Netherlands.
authors.forename: Dominic
authors.initials: D
authors.lastname: Snijders
authors.affiliation: Department of Hematology, VU Medical Centre, Amsterdam, The Netherlands.
authors.forename: Martine
authors.initials: M
authors.lastname: Chamuleau
authors.affiliation: Department of Pulmonology and Tuberculosis, Spaarne Ziekenhuis, Hoofddorp, The Netherlands.
authors.forename: Anita
authors.initials: A
authors.lastname: Griffioen
mesh_terms: D000368:Aged; D006801:Humans; D016399:Lymphoma, T-Cell / Q000150:complications*; D008297:Male; D016926:Mycobacterium chelonae / Q000254:growth & development* / Q000472:pathogenicity
keywords: Anti-CC chemokine receptor 4 antibody; Mogamulizumab; Mycobacterium chelonae; Non-Hodgkin lymphoma; Rapidly growing mycobacteria; T-cell lymphoma