title: Relationships between high-density lipoprotein cholesterol and depressive symptoms: Findings of the Korean National Health and Nutrition Examination Survey (KNHANES).
abstract: Although serum cholesterol has been associated with late-life depression, few studies on the associations between lipids and depression among middle-aged adults have been performed. This study examined associations between serum lipid levels and depressive symptoms in Korean middle-aged adults. We used data from 8207 participants aged 40-64 years who completed a questionnaire about their experience of depressive symptoms over the last year as part of the 2010-2012 Korean National Health and Nutrition Examination Survey. Higher HDL-C levels were significantly associated with an elevated risk of depressive symptoms (OR=1.32; 95% CI=1.09-1.60) after adjusting for other covariates.
authors.affiliation: Department of Biomedical Science, Chonnam National University Medical School, Gwangju, South Korea.
authors.forename: Hee-Young
authors.initials: HY
authors.lastname: Shin
authors.affiliation: Division of Clinical Pharmacology, Chonnam National University Hospital, Gwangju, South Korea.
authors.forename: Gaeun
authors.initials: G
authors.lastname: Kang
authors.affiliation: Department of Psychiatry, Chonnam National University Medical School, Gwangju, South Korea.
authors.forename: Hee-Ju
authors.initials: HJ
authors.lastname: Kang
authors.affiliation: Department of Psychiatry, Chonnam National University Medical School, Gwangju, South Korea.
authors.forename: Sung-Wan
authors.initials: SW
authors.lastname: Kim
authors.affiliation: Department of Psychiatry, Chonnam National University Medical School, Gwangju, South Korea.
authors.forename: Il-Seon
authors.initials: IS
authors.lastname: Shin
authors.affiliation: Department of Psychiatry, Chonnam National University Medical School, Gwangju, South Korea.
authors.forename: Jin-Sang
authors.initials: JS
authors.lastname: Yoon
authors.affiliation: Department of Psychiatry, Chonnam National University Medical School, Gwangju, South Korea. Electronic address: jmkim@chonnam.ac.kr.
authors.forename: Jae-Min
authors.initials: JM
authors.lastname: Kim
mesh_terms: D000328:Adult; D008076:Cholesterol, HDL / Q000097:blood*; D003863:Depression / Q000097:blood*; D005260:Female; D006306:Health Surveys / Q000706:statistics & numerical data; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys / Q000706:statistics & numerical data; D056910:Republic of Korea / Q000453:epidemiology
chemical_list: D008076:Cholesterol, HDL
keywords: Cholesterol; Depression; HDL; Lipids; Middle-aged