title: Measuring recovery of visual function in children with papilledema using sweep visual evoked potentials.
abstract: To assess visual function in children with papilledema using sweep visual evoked potentials (VEP) to determine whether vision function improved following treatment.
  
  
  
  Contrast sensitivity and grating acuity were prospectively measured by using sweep visual evoked potential testing in children with mild or moderate acute papilledema. A subset of children were tested longitudinally before and after treatment. Subject data was compared with that of age-matched controls using the Wilcoxon-Mann-Whitney test.
  
  
  
  A total of 9 subjects (age range, 9-16 years) and 11 controls were included; 5 subjects were studied longitudinally. The control group's logMAR grating acuity (mean, 0.09; range, -0.13 to 0.36) was better than that of the papilledema group (mean, 0.36; range 0.15-0.59). Four patients showed recovery of contrast sensitivity following treatment of their raised intracranial pressure between first and last visit.
  
  
  
  In our study cohort, sweep VEP was able to detect early improvement in contrast sensitivity despite absence of apparent clinical change in disk edema in children undergoing treatment for raised intracranial pressure.
authors.affiliation: Department of Ophthalmology, Rambam Health Care Campus, Israel Institute of Technology, Haifa, Israel; Ruth & Bruce Rappaport Faculty of Medicine, Technion, Israel Institute of Technology, Haifa, Israel. Electronic address: emezer@gmail.com.
authors.forename: Eedy
authors.initials: E
authors.lastname: Mezer
authors.affiliation: Departments of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
authors.forename: Carol A
authors.initials: CA
authors.lastname: Westall
authors.affiliation: Department of Psychology, The Hospital for Sick Children, Toronto, Canada.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mirabella
authors.affiliation: Goldshleger Eye Institute, Sheba Medical Center, Tel-Hashomer, Israel; Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
authors.forename: Tamara
authors.initials: T
authors.lastname: Wygnanski-Jaffe
authors.affiliation: Departments of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
authors.forename: Ronit
authors.initials: R
authors.lastname: Yagev
authors.affiliation: Departments of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada; Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Canada.
authors.forename: J Raymond
authors.initials: JR
authors.lastname: Buncic
mesh_terms: D000293:Adolescent; D002648:Child; D015331:Cohort Studies; D015350:Contrast Sensitivity / Q000502:physiology; D005074:Evoked Potentials, Visual / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D010211:Papilledema / Q000503:physiopathology*; D020127:Recovery of Function / Q000502:physiology*; D014786:Vision Disorders / Q000503:physiopathology*; D014787:Vision Tests; D014792:Visual Acuity / Q000502:physiology*