title: Ratiometric detection and imaging of endogenous hypochlorite in live cells and in vivo achieved by using an aggregation induced emission (AIE)-based nanoprobe.
abstract: An AIE-based fluorescent nanoprobe (MTPE-M) has been developed and used for ratiometric detection of hypochlorite with high selectivity and sensitivity. More importantly, its application in live cells and zebrafish for ratiometric imaging of endogenous ClO(-) has also been achieved.
authors.affiliation: College of Materials Science & Engineering, State Key Lab of Luminescent Materials & Devices, South China University of Technology, Guangzhou 510640, P. R. China. shzhwu@scut.edu.cn.
authors.forename: Yong
authors.initials: Y
authors.lastname: Huang
authors.forename: Peisheng
authors.initials: P
authors.lastname: Zhang
authors.forename: Meng
authors.initials: M
authors.lastname: Gao
authors.forename: Fang
authors.initials: F
authors.lastname: Zeng
authors.forename: Anjun
authors.initials: A
authors.lastname: Qin
authors.forename: Shuizhu
authors.initials: S
authors.lastname: Wu
authors.forename: Ben Zhong
authors.initials: BZ
authors.lastname: Tang
mesh_terms: D000818:Animals; D005456:Fluorescent Dyes / Q000737:chemistry*; D017665:Hydroxyl Radical / Q000737:chemistry; D006997:Hypochlorous Acid / Q000032:analysis* / Q000737:chemistry; D007814:Larva / Q000737:chemistry / Q000378:metabolism; D051379:Mice; D008856:Microscopy, Fluorescence; D053758:Nanoparticles / Q000737:chemistry*; D061848:Optical Imaging; D000067996:RAW 264.7 Cells; D013050:Spectrometry, Fluorescence; D021241:Spectrometry, Mass, Electrospray Ionization; D015027:Zebrafish / Q000254:growth & development / Q000378:metabolism
chemical_list: D005456:Fluorescent Dyes; D017665:Hydroxyl Radical; D006997:Hypochlorous Acid