title: Concurrent Intraventricular and Sacral Spinal Drop Metastasis of Ganglioglioma in an Adult Patient: A Case Report and Review of Literature.
abstract: Gangliogliomas are uncommon tumors of the central nervous system and rarely occur in the lateral ventricle or present with drop metastasis. We report a 49-year-old male who presented with a six-week history of left leg pain and numbness. Clinical examination revealed no focal neurological deficits. Magnetic resonance imaging (MRI) demonstrated enhancing nodular lesions in the sacral spine abutting the S2 nerve root. Further imaging of the neuroaxis demonstrated a cystic lesion in the left frontal horn of the lateral ventricle. Gross total surgical resection of the ventricular lesion was performed through a transcortical approach, followed by resection of the sacral spinal drop metastasis in a staged manner. A histopathological analysis revealed the diagnosis of low-grade ganglioglioma. To our knowledge, this is the first reported case of a low-grade intraventricular ganglioglioma presenting with symptoms associated with drop metastasis in an adult patient.
authors.affiliation: Neurosurgery, Medstar Georgetown University Hospital.
authors.forename: Hasan R
authors.initials: HR
authors.lastname: Syed
authors.affiliation: Neurosurgery, Holy Cross Hospital.
authors.forename: Jay W
authors.initials: JW
authors.lastname: Rhee
authors.affiliation: Neurosurgery, Medstar Georgetown University Hospital.
authors.forename: Ribhu T
authors.initials: RT
authors.lastname: Jha
authors.affiliation: Neurosurgery, Medstar Georgetown University Hospital.
authors.forename: Daniel
authors.initials: D
authors.lastname: Felbaum
authors.affiliation: Neurosurgery, Medstar Georgetown University Hospital.
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Kalhorn
keywords: drop metastasis; ganglioglioma; intraventricular; sacral; spinal metastasis