title: [PREDICTORS OF MODERATE COGNITIVE DISORDERS IN PATIENTS WITH CORONARY HEART DISEASE AND TYPE 2 DIABETES MELLITUS].
abstract: OBJECTIVE
  To study predictors of moderate cognitive disorders (MCD) in patients with coronary heart disease (CHD) and type 2 diabetes mellitus (DM2).
  
  
  METHODS
  The study included 54 men with CPD andDM2 (mean age 56.8 ± 4.5 years). Standard medical examination was supplemented by the assessment of cognitive status, characteristics of lipid and carbohydrate metabolism. Factors allegedly influencing MCD development included the patients' age, education level, stenosis of carotid arteries, LV ejection fraction, arterial hypertension, insulin and HbAlc levels, HOMA and QUICKI indices, lipid metabolism, concentrations of total, HDL and LDL cholesterol, fructosamine, triglycerides, severity of coronary lesions (Syntax scale), trait and state anxiety.
  
  
  RESULTS
  Fructosamine level and HOMA index were the most important characteristics responsible for MCD in patients with CPD and DM2.
  
  
  CONCLUSIONS
  The data obtained demonstrate the significance of fructosamine level and HOMA index in the development of MCD in patients with CPD and DM2.
authors.forename: O A
authors.initials: OA
authors.lastname: Trubnikova
authors.forename: I V
authors.initials: IV
authors.lastname: Tarasova
authors.forename: A S
authors.initials: AS
authors.lastname: Mamontova
authors.forename: E S
authors.initials: ES
authors.lastname: Kagan
authors.forename: O V
authors.initials: OV
authors.lastname: Maleva
authors.forename: O L
authors.initials: OL
authors.lastname: Barbarash
mesh_terms: D000367:Age Factors; D000368:Aged; D050260:Carbohydrate Metabolism; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D003324:Coronary Artery Disease / Q000150:complications / Q000175:diagnosis / Q000523:psychology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood / Q000150:complications / Q000175:diagnosis / Q000523:psychology; D004522:Educational Status; D019270:Fructosamine / Q000097:blood*; D006442:Glycated Hemoglobin / Q000032:analysis; D006801:Humans; D007328:Insulin / Q000097:blood; D050356:Lipid Metabolism; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012372:ROC Curve; D012307:Risk Factors
chemical_list: D019270:Fructosamine; D006442:Glycated Hemoglobin; D007328:Insulin