title: Effects of temperature variation between neighbouring days on daily hospital visits for childhood asthma: a time-series analysis.
abstract: OBJECTIVE
  To identify the relationship between temperature variation between neighbouring days (TVN) and hospital visits for childhood asthma in age- and sex-specific groups.
  
  
  METHODS
  An ecological design was used to explore the effect of TVN on hospital visits for childhood asthma.
  
  
  METHODS
  A Poisson generalised linear regression model combined with a distributed lag non-linear model was used to analyse the association between TVN and hospital visits for childhood asthma. All hospital visits for childhood asthma from June 2010 to July 2013 were included (n = 17,022). Daily climate data were obtained from Hefei Meteorological Bureau.
  
  
  RESULTS
  A significant correlation was found between TVN and hospital visits for childhood asthma in age- and sex-specific groups. For different gender groups, the effect of TVN on childhood asthma was the greatest at 3 and 5 days lag for males and females. For different age groups, the effect of TVN on childhood asthma was the greatest at 1 and 5 days lag for 0-4 years and 5-14 years children, respectively. A 1 °C increase in TVN was associated with a 4.2% (95% confidence interval 0.9-7.6%) increase in hospital visits for childhood asthma.
  
  
  CONCLUSIONS
  TVN is associated with hospital visits for childhood asthma. Once the temperature change rapidly, guardians will be urged to pay more attention to their children's health, which may reduce the morbidity of childhood asthma.
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
authors.forename: K
authors.initials: K
authors.lastname: Li
authors.affiliation: Anhui Provincial Children's Hospital, Hefei, Anhui, China.
authors.forename: H
authors.initials: H
authors.lastname: Ni
authors.affiliation: Anhui Provincial Children's Hospital, Hefei, Anhui, China.
authors.forename: Z
authors.initials: Z
authors.lastname: Yang
authors.affiliation: Anhui Provincial Children's Hospital, Hefei, Anhui, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Wang
authors.affiliation: The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
authors.forename: S
authors.initials: S
authors.lastname: Ding
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
authors.forename: L
authors.initials: L
authors.lastname: Wen
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
authors.forename: H
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
authors.forename: J
authors.initials: J
authors.lastname: Cheng
authors.affiliation: Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China. Electronic address: suhong5151@sina.com.
authors.forename: H
authors.initials: H
authors.lastname: Su
mesh_terms: D000293:Adolescent; D001249:Asthma / Q000453:epidemiology / Q000628:therapy*; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D057231:Climate Change / Q000706:statistics & numerical data*; D005260:Female; D006761:Hospitals / Q000706:statistics & numerical data*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D016014:Linear Models; D008297:Male; D016012:Poisson Distribution; D013696:Temperature; D013997:Time Factors
keywords: Asthma; Childhood; Climate change; Temperature variation