title: Double primary malignant fibrous histiocytoma and squamous cell carcinoma of the larynx treated with laser laryngeal conservation surgery.
abstract: Synchronous multiple malignancies of the larynx are rare. We present a case here of synchronous primary laryngeal squamous cell carcinoma (SCC) and malignant fibrous histiocytoma (MFH) in a patient with hoarseness though with no history of exposure to radiation. Clinical, intraoperative, and histopathological findings in this patient are discussed.
  
  
  METHODS
  Wide laser excision of the left supraglottic lesion and laser cordectomy of the right true vocal cord were performed.
  
  
  RESULTS
  The patient presented with a recurrence of the ΜFH alone (with no recurrence of the SCC) two months after the first operation and was managed with an extended second look laser cordectomy. The patient is under regular follow-up and remained disease-free nine months from diagnosis.
  
  
  CONCLUSIONS
  Our results show that early-stage simultaneous tumours of the larynx and particularly MFH and SCC can be treated efficiently with endoscopic laryngeal surgery alone. Close follow-up is of paramount importance because of the aggressive nature of MFH.
authors.affiliation: Department of Otolaryngology-Head Neck Surgery, Ahepa University Hospital, Thessaloniki 546 21, Greece.
authors.forename: P D
authors.initials: PD
authors.lastname: Karkos
authors.affiliation: Department of Otolaryngology-Head Neck Surgery, Ahepa University Hospital, Thessaloniki 546 21, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Dova
authors.affiliation: Department of Histopathology, Aristotle University of Thessaloniki, Thessaloniki 546 21, Greece.
authors.forename: S
authors.initials: S
authors.lastname: Sotiriou
authors.affiliation: Department of Otolaryngology-Head Neck Surgery, Ahepa University Hospital, Thessaloniki 546 21, Greece.
authors.forename: K
authors.initials: K
authors.lastname: Markou
authors.affiliation: Department of Histopathology, Aristotle University of Thessaloniki, Thessaloniki 546 21, Greece.
authors.forename: I
authors.initials: I
authors.lastname: Kostopoulos
keywords: fibrous histiocytoma; larynx; laser; squamous cell carcinoma