title: Secretin-Stimulated Magnetic Resonance Imaging Assessment of the Benign Pancreatic Disorders: Systematic Review and Proposal for a Standardized Protocol.
abstract: This systemic review summarizes the current literature and general consensus on secretin-stimulated magnetic resonance imaging (s-MRI) of the benign pancreatic disorders and discusses important aspects on how s-MRI is optimally performed. The aim is to provide an overview, for clinicians and radiologist, of the s-MRI protocols and the range of clinical applications. Furthermore, the review will summarize the criteria for evaluation of pancreatic morphology and function based on s-MRI.The literature search indentified 69 original articles and 15 reviews. Chronic pancreatitis was the disease that was most frequently assessed by s-MRI (33%), followed by acute pancreatitis (9%). Dynamic thick-slab 2-dimensional magnetic resonance cholangiopancreatography was the most used imaging sequence (86%). The diameter of the main pancreatic duct (75%) and pancreatic exocrine function based on visual grading of duodenal filling (67%) were the most evaluated pancreatic features. Sufficient similarities between studies were identified to propose the most agreeable standardized s-MRI protocol for morphological and functional assessment of the pancreas. In the future, more research and increased collaboration between centers is necessary to achieve more consensus and optimization of s-MRI protocols.
authors.affiliation: From the Departments of *Radiology and †Gastroenterology & Hepatology, Mech-Sense, Aalborg University Hospital, Aalborg, Denmark; ‡Department of Radiology, Haukeland University Hospital; and §Section for Radiology, Department of Clinical Medicine, University of Bergen, Bergen, Norway; and ∥Department of Clinical Medicine, Aalborg University, Aalborg, Denmark.
authors.forename: Adnan
authors.initials: A
authors.lastname: Madzak
authors.forename: Søren Schou
authors.initials: SS
authors.lastname: Olesen
authors.forename: Gaute Kjellevold
authors.initials: GK
authors.lastname: Wathle
authors.forename: Ingfrid Salvesen
authors.initials: IS
authors.lastname: Haldorsen
authors.forename: Asbjørn Mohr
authors.initials: AM
authors.lastname: Drewes
authors.forename: Jens Brøndum
authors.initials: JB
authors.lastname: Frøkjær
mesh_terms: D049448:Cholangiopancreatography, Magnetic Resonance; D006801:Humans; D008279:Magnetic Resonance Imaging; D010179:Pancreas; D010182:Pancreatic Diseases; D010186:Pancreatic Function Tests; D012633:Secretin; D000078202:Systematic Reviews as Topic
chemical_list: D012633:Secretin