title: [Clinical presentation of supratentorial and infratentorial intracranial tumors in pediatric patients].
abstract: BACKGROUND
  Brain tumors are the second most common malignancy in childhood and they are also the most common solid tumors in children and the most frequent cause of morbidity and mortality associated with cancer in this age.
  
  
  OBJECTIVE
  To determine the clinical presentation of supratentorial and infratentorial intracranial tumors in pediatric patients.
  
  
  METHODS
  An observational, retrospective, cross-sectional comparative study in which records the clinical manifestations of 51 pediatric patients diagnosed with intracranial tumor, according with its location, supra- or infratentorial.
  
  
  RESULTS
  51 patients were analyzed. Tumor location was infratentorial in 32 patients (62.7%) and supratentorial in 19 (37.3%). Cerebellar syndrome occurred in 21 patients (65.6 %) with infratentorial tumor compared with six (31.5 %) with supratentorial tumor (p = 0.04; OR: 3.2; 95% CI: 1.1-12.8). Nystagmus was significantly more common in patients with infratentorial tumors (p = 0.029). Endocrine manifestations were present in four patients (21%) with supratentorial tumor and none of the infratentorial group (p = 0.03).
  
  
  CONCLUSIONS
  Cerebellar syndrome was statistically significantly more common in patients with infratentorial when compared with patients with supratentorial. Nystagmus is one of the most common visual impairments in patients with infratentorial tumor. Endocrine disorders are significantly more frequent in patients with supratentorial tumor. The interval between onset of symptoms and diagnosis of intracranial tumor is significantly longer in children with supratentorial tumor because the symptoms are more insidious in onset and are mistaken for other benign conditions.
authors.affiliation: Departamento de Pediatría, UMAE No. 25, Monterrey, N.L., México.
authors.forename: Luz María
authors.initials: LM
authors.lastname: Sánchez-Sánchez
authors.affiliation: Departamento de Pediatría, UMAE No. 25, Monterrey, N.L., México.
authors.forename: Javier
authors.initials: J
authors.lastname: Vázquez-Moreno
authors.affiliation: Departamento de Pediatría, UMAE No. 25, Monterrey, N.L., México.
authors.forename: José Antonio
authors.initials: JA
authors.lastname: Heredia-Delgado
authors.affiliation: Departamento de Pediatría, UMAE No. 25, Monterrey, N.L., México.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Sevilla-Castillo
mesh_terms: D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D015192:Infratentorial Neoplasms / Q000175:diagnosis*; D008297:Male; D012189:Retrospective Studies; D015173:Supratentorial Neoplasms / Q000175:diagnosis*