title: Cancer Screening in Older Patients.
abstract: Although cancer is the second leading cause of death among persons 65 years and older, there is a paucity of clinical trial data about the effectiveness and harms of cancer screening in this population. Given the heterogeneous nature of the older population, cancer screening in these patients should not be based on age alone. Studies suggest that a life expectancy of at least 10 years is necessary to derive a survival benefit from screening for breast and colorectal cancers; therefore, screening for these cancers is not recommended in those with a life expectancy of less than 10 years. Prostate cancer screening, if performed at all, should not be performed after 69 years of age. Cervical cancer screening may be stopped after 65 years of age if the patient has an adequate history of negative screening results. An individualized approach to cancer screening decisions involves estimating life expectancy, determining the potential benefits and harms of screenings, and weighing those benefits and harms in relation to the patient's values and preferences.
authors.affiliation: Thomas Jefferson University, Philadelphia, PA, USA.
authors.forename: Brooke
authors.initials: B
authors.lastname: Salzman
authors.affiliation: Crozer-Chester Medical Center, Upland, PA, USA.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Beldowski
authors.affiliation: Drexel University College of Medicine, Philadelphia, PA, USA.
authors.forename: Amanda
authors.initials: A
authors.lastname: de la Paz
mesh_terms: D000367:Age Factors; D000368:Aged; D001943:Breast Neoplasms / Q000175:diagnosis; D015179:Colorectal Neoplasms / Q000175:diagnosis; D055088:Early Detection of Cancer / Q000592:standards*; D005260:Female; D006801:Humans; D008017:Life Expectancy; D008175:Lung Neoplasms / Q000175:diagnosis; D008297:Male; D009369:Neoplasms / Q000175:diagnosis*; D017410:Practice Guidelines as Topic; D011471:Prostatic Neoplasms / Q000175:diagnosis; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis