title: Preparation and characterization of cellulose composite hydrogels from tea residue and carbohydrate additives.
abstract: Composite hydrogels were prepared from tea cellulose in ionic liquid of 1-allyl-3-methylimidazolium chloride and effect of κ-carrageenan, chitosan, guar gum and soluble starch on characteristics of the prepared hydrogels were investigated. The prepared hydrogels were characterized via Fourier transform infrared, thermogravimetry analysis, differential scanning calorimetry. Sodium salicylate was used as the model drug to compare the swelling, drug loading and releasing kinetics of the prepared hydrogels. Thiazolyl blue tetrazolium bromide assay and relative growth rates were adopted to evaluate cell cytotoxicity and biocompatibility of the prepared hydrogels. Chitosan and guar gum could improve thermostability and mechanical characteristics of the composite hydrogels, while κ-carrageenan or soluble starch could improve equilibrium swelling ratio, sodium salicylate loading and releasing. Guar gum and chitosan could increase permeation resistance and were beneficial for release control of the hydrogels. Addition of chitosan, κ-carrageenan, guar gum and soluble starch were proven cell compatibility and non-cytotoxicity.
authors.affiliation: School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China; Guangdong Polytechnic of Science and Trade, Guangzhou 510430, China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Liu
authors.affiliation: School of Food Science and Engineering, South China University of Technology, Guangzhou 510640, China. Electronic address: fehhuang@scut.edu.cn.
authors.forename: Huihua
authors.initials: H
authors.lastname: Huang
mesh_terms: D000498:Allyl Compounds / Q000737:chemistry; D028241:Camellia sinensis / Q000737:chemistry*; D002470:Cell Survival; D002482:Cellulose; D048271:Chitosan / Q000737:chemistry; D004337:Drug Carriers / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D005685:Galactans / Q000737:chemistry; D020100:Hydrogels / Q000138:chemical synthesis* / Q000737:chemistry / Q000633:toxicity; D007093:Imidazoles / Q000737:chemistry; D008351:Mannans / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D053149:Plant Gums / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C544334:1-allyl-3-methylimidazolium; D000498:Allyl Compounds; D004337:Drug Carriers; D005685:Galactans; D020100:Hydrogels; D007093:Imidazoles; D008351:Mannans; D053149:Plant Gums; D002482:Cellulose; D048271:Chitosan; C007894:guar gum
keywords: Cell compatibility; Characterization; Composite hydrogel; Ionic liquid; Tea cellulose