title: [Infective endocarditis : Update on prophylaxis, diagnosis, and treatment].
abstract: The diagnosis of infective endocarditis is often delayed in clinical practice. Timely diagnosis and rapid antibiotic treatment is important. Higher age of patients, new risk factors, and increasing use of intravascular prosthetic materials resulted in changes in microbial spectrum. Nowadays, nonspecific symptoms, critically ill patients, and immunocompromised patients require a high level of diagnostic expertise.The new guidelines from the European Society of Cardiology provide various diagnostic algorithms and recommendations for antibiotic treatment. The new guidelines also recommend the formation of an endocarditis team with various medical disciplines, including a cardiac surgeon, to improve treatment because in half of all endocarditis patients, antibiotic therapy alone does not result in successful management of the infection. If complications occur, early surgical treatment should be performed.In this overview, diagnostic strategies and therapeutic approaches for the treatment of infectious endocarditis according to the current guidelines and aspects of surgical treatment are provided.
authors.affiliation: Medizinische Klinik II, Kardiologie, Angiologie und Internistische Intensivmedizin, St. Marien-Krankenhaus Siegen, Kampenstr. 51, 57072, Siegen, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Dietz
authors.affiliation: Medizinische Klinik II, Kardiologie, Angiologie und Internistische Intensivmedizin, St. Marien-Krankenhaus Siegen, Kampenstr. 51, 57072, Siegen, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Lemm
authors.affiliation: Medizinische Klinik II, Kardiologie, Angiologie und Internistische Intensivmedizin, St. Marien-Krankenhaus Siegen, Kampenstr. 51, 57072, Siegen, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Janusch
authors.affiliation: Medizinische Klinik II, Kardiologie, Angiologie und Internistische Intensivmedizin, St. Marien-Krankenhaus Siegen, Kampenstr. 51, 57072, Siegen, Deutschland. m.buerke@marienkrankenhaus.com.
authors.forename: M
authors.initials: M
authors.lastname: Buerke
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001431:Bacteriological Techniques; D057210:Delayed Diagnosis; D004452:Echocardiography; D017548:Echocardiography, Transesophageal; D004696:Endocarditis / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology / Q000517:prevention & control; D019983:Guideline Adherence; D006801:Humans; D007362:Intensive Care Units; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents
keywords: Bacterial endocarditis; Cardiac surgical procedures; Guidelines; Heart valves; Prophylaxis