title: The Development of Orange Pigment Overlying Choroidal Metastasis.
abstract: OBJECTIVE
  The aim of this study was to correlate the ophthalmoscopic and histopathological findings of orange pigment overlying a choroidal metastasis.
  
  
  METHODS
  This is a single case report with clinical follow-up and histopathological examination.
  
  
  RESULTS
  Histopathology revealed a choroidal metastasis with subretinal CD68-positive macrophages showing autofluorescent deposits in fluorescence microscopy.
  
  
  CONCLUSIONS
  The development of orange pigment is not pathognomonic for choroidal melanoma but may be seen in other lesions such as carcinoma metastasis.
authors.affiliation: Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany.
authors.forename: Aline Isabel
authors.initials: AI
authors.lastname: Riechardt
authors.affiliation: Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany.
authors.forename: Enken
authors.initials: E
authors.lastname: Gundlach
authors.affiliation: Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany.
authors.forename: Antonia M
authors.initials: AM
authors.lastname: Joussen
authors.affiliation: Department of Ophthalmology, Charité Universitätsmedizin, Berlin, Germany; Klinik für Augenheilkunde, DRK Kliniken Westend, Berlin, Germany.
authors.forename: Gregor D
authors.initials: GD
authors.lastname: Willerding
keywords: Choroidal melanoma; Choroidal metastasis; Orange pigment