title: Access to Indole Derivatives from Diaryliodonium Salts and 2-Alkynylanilines.
abstract: An efficient, environmentally friendly, and operationally simple procedure to 1,2-disubstituted indoles from 2-alkynylanilines and diaryliodonium salts has been developed. This reaction proceeds smoothly under metal-free conditions. The products obtained could be transferred into 3,3'-diindolylmethane with DMSO catalyzed by palladium. The isotopic label experiments indicated that the methylene group in 3,3'-diindolylmethane is derived from DMSO. The diverse indoles were obtained in up to 90% yield for 28 examples.
authors.affiliation: Key Laboratory of Xiamen Marine and Gene Drugs, Institutes of Molecular Medicine and School of Biomedical Sciences, Huaqiao University & Engineering Research Center of Molecular Medicine, Ministry of Education , Xiamen 361021, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Li
authors.affiliation: Key Laboratory of Xiamen Marine and Gene Drugs, Institutes of Molecular Medicine and School of Biomedical Sciences, Huaqiao University & Engineering Research Center of Molecular Medicine, Ministry of Education , Xiamen 361021, China.
authors.forename: Yunxiang
authors.initials: Y
authors.lastname: Weng
authors.affiliation: Key Laboratory of Xiamen Marine and Gene Drugs, Institutes of Molecular Medicine and School of Biomedical Sciences, Huaqiao University & Engineering Research Center of Molecular Medicine, Ministry of Education , Xiamen 361021, China.
authors.forename: Xianxiang
authors.initials: X
authors.lastname: Xu
authors.affiliation: Key Laboratory of Xiamen Marine and Gene Drugs, Institutes of Molecular Medicine and School of Biomedical Sciences, Huaqiao University & Engineering Research Center of Molecular Medicine, Ministry of Education , Xiamen 361021, China.
authors.forename: Xiuling
authors.initials: X
authors.lastname: Cui