title: Overlap of IgG4-related Disease and Primary Biliary Cirrhosis Complicated with Autoimmune Thrombocytopenia.
abstract: A 63-year-old woman was referred to Fukushima Red Cross Hospital with an enlargement of the left submandibular gland and subcutaneous bleeding in the chest and legs. A diffuse enlargement of the pancreas was also detected by abdominal computed tomography, and laboratory data showed severe thrombocytopenia. She was diagnosed with IgG4-related disease (IgG4-RD) complicated with autoimmune thrombocytopenia and was treated with methylprednisolone, after which the number of platelets favorably increased. Further investigation for liver dysfunction revealed underlying primary biliary cirrhosis (PBC). We herein report a rare case of IgG4-RD overlapping PBC complicated with autoimmune thrombocytopenia.
authors.affiliation: Department of Internal Medicine and Gastroenterology, Fukushima Red Cross Hospital, Japan.
authors.forename: Mika
authors.initials: M
authors.lastname: Takasumi
authors.forename: Masayuki
authors.initials: M
authors.lastname: Miyata
authors.forename: Masahito
authors.initials: M
authors.lastname: Kuroda
authors.forename: Kumiko
authors.initials: K
authors.lastname: Terashima
authors.forename: Kazumichi
authors.initials: K
authors.lastname: Abe
authors.forename: Atsushi
authors.initials: A
authors.lastname: Takahashi
authors.forename: Hiroko
authors.initials: H
authors.lastname: Kobayashi
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Tazaki
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Watanabe
authors.forename: Hiromasa
authors.initials: H
authors.lastname: Ohira
mesh_terms: D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008105:Liver Cirrhosis, Biliary / Q000150:complications*; D008775:Methylprednisolone / Q000627:therapeutic use; D008875:Middle Aged; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications* / Q000188:drug therapy; D013363:Submandibular Gland / Q000473:pathology; D014057:Tomography, X-Ray Computed
chemical_list: D007074:Immunoglobulin G; D008775:Methylprednisolone