title: Positive evidence for vitamin A role in prevention of type 1 diabetes.
abstract: Type 1 diabetes mellitus (T1DM) as one of the most well-known autoimmune disease, results from the destruction of β-cells in pancreas by autoimmune process. T1DM is fatal without insulin treatment. The expansion of alternative treatment to insulin is a dream to be fulfilled. Currently autoimmunity is considered as main factor in development of T1DM. So manipulation of the immune system can be considered as alternative treatment to insulin. For the past decades, vitamin A has been implicated as an essential dietary micronutrient in regulator of immune function. Despite major advantage in the knowledge of vitamin A biology, patients who present T1DM are at risk for deficiency in vitamin A and carotenoids. Applying such evidences, vitamin A treatment may be the key approach in preventing T1DM.
authors.affiliation: Somaye Yosaee, Maryam Akbari Fakhrabadi, Farzad Shidfar, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran 14665-1579, Iran.
authors.forename: Somaye
authors.initials: S
authors.lastname: Yosaee
authors.affiliation: Somaye Yosaee, Maryam Akbari Fakhrabadi, Farzad Shidfar, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran 14665-1579, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Akbari Fakhrabadi
authors.affiliation: Somaye Yosaee, Maryam Akbari Fakhrabadi, Farzad Shidfar, Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran 14665-1579, Iran.
authors.forename: Farzad
authors.initials: F
authors.lastname: Shidfar
keywords: Autoimmune; Diabetes; Insulin; Pancreas; Vitamin A