title: T2- and diffusion-weighted magnetic resonance imaging at 3T for the detection of prostate cancer with and without endorectal coil: An intraindividual comparison of image quality and diagnostic performance.
abstract: OBJECTIVE
  To intraindividually compare image quality and diagnostic performance of multiparametric MRI (mpMRI) at 3T for the detection of prostate cancer (PCa) using a pelvic phased-array coil (PAC) and a combined endorectal and pelvic phased-array coil (ERC-PAC).
  
  
  METHODS
  Forty-five patients were prospectively included and received mpMRI of the prostate using a PAC and an ERC-PAC during one imaging session. Two radiologists evaluated image quality and the most suspicious lesion according to the PI-RADS scoring system. Results of MRI-TRUS-fusion biopsy of the prostate served as reference standard. Patient comfort and acceptance were assessed using a standardized questionnaire.
  
  
  RESULTS
  Overall image quality for T2WI was rated significantly better with an ERC-PAC compared to a PAC (p=0.0038). The weighted kappa for PI-RADS scores for T2WI and DWI with a PAC and an ERC-PAC was 0.70 and 0.73, respectively. For a PI-RADS sum score including T2WI and DWI the area under the curve with a PAC and an ERC-PAC were 0.95-0.99 and 0.93-0.97, respectively (p=0.1395).
  
  
  CONCLUSIONS
  For T2WI and DWI performed at 3T index PCa lesion identification and evaluation did not differ significantly with both coil setups. Patients preferred MRI without an ERC. Therefore, the use of an ERC may be omitted in a prostate cancer detection setting.
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Strahlenheilkunde, Berlin, Germany.
authors.forename: Alexander D J
authors.initials: AD
authors.lastname: Baur
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Strahlenheilkunde, Berlin, Germany.
authors.forename: Tareef
authors.initials: T
authors.lastname: Daqqaq
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Strahlenheilkunde, Berlin, Germany.
authors.forename: Moritz
authors.initials: M
authors.lastname: Wagner
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Urologie, Berlin, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Maxeiner
authors.affiliation: Klinikum Ernst von Bergmann gGmbh, Potdsam, Germany.
authors.forename: Alexander
authors.initials: A
authors.lastname: Huppertz
authors.affiliation: Klinikum Ernst von Bergmann gGmbh, Potdsam, Germany.
authors.forename: Diane
authors.initials: D
authors.lastname: Renz
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Strahlenheilkunde, Berlin, Germany.
authors.forename: Bernd
authors.initials: B
authors.lastname: Hamm
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Strahlenheilkunde, Berlin, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Fischer
authors.affiliation: Charité-Universitätsmedizin Berlin, Campus Charité Mitte, Klinik für Strahlenheilkunde, Berlin, Germany. Electronic address: tahir.durmus@charite.de.
authors.forename: Tahir
authors.initials: T
authors.lastname: Durmus
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D019540:Area Under Curve; D016477:Artifacts; D015331:Cohort Studies; D003287:Contrast Media / Q000008:administration & dosage; D038524:Diffusion Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D007089:Image Enhancement / Q000295:instrumentation / Q000379:methods*; D061705:Image-Guided Biopsy / Q000379:methods; D008279:Magnetic Resonance Imaging / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D064847:Multimodal Imaging / Q000379:methods; D009942:Organometallic Compounds / Q000008:administration & dosage; D017060:Patient Satisfaction; D011446:Prospective Studies; D011467:Prostate / Q000000981:diagnostic imaging; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*; D012007:Rectum / Q000000981:diagnostic imaging; D015203:Reproducibility of Results; D014463:Ultrasonography / Q000379:methods
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C090600:gadobutrol
keywords: Coil; MRI; PI-RADS; Prostate cancer