title: [Approach to the Patient with Elevated Serum Ferritin].
abstract: An increase of the serum ferritin may appear as an incidental finding in asymptomatic patients in the routine laboratory examination. On the one hand, ferritin reflects the iron stores of the body and can therefore indicate an iron overload of various causes. On the other hand, it is an acute phase protein and thus increases in inflammatory and malignant diseases. We aim to describe an approach to the incidental finding hyperferritinemia with possible evaluation strategy and to explain the most important differential diagnoses.
authors.affiliation: 1 Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.
authors.forename: Florentine
authors.initials: F
authors.lastname: Schreiner
authors.affiliation: 2 Klinik für Innere Medizin, Spital Linth.
authors.forename: Pierre-Alexandre
authors.initials: PA
authors.lastname: Krayenbühl
authors.affiliation: 3 Klinik für Hämatologie, Universitätsspital Zürich und Klinik für Medizinische Onkologie und Hämatologie, Kantonsspital Winterthur.
authors.forename: Jeroen
authors.initials: J
authors.lastname: Goede
authors.affiliation: 1 Klinik und Poliklinik für Innere Medizin, Universitätsspital Zürich.
authors.forename: Albina
authors.initials: A
authors.lastname: Nowak
mesh_terms: D000465:Algorithms; D003937:Diagnosis, Differential; D004867:Equipment Design; D004907:Erythrocyte Deformability; D005293:Ferritins / Q000097:blood*; D006403:Hematologic Tests / Q000295:instrumentation; D006432:Hemochromatosis / Q000097:blood / Q000175:diagnosis; D006486:Hemosiderosis / Q000097:blood / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D006801:Humans; D033162:Incidental Findings; D019190:Iron Overload / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D008099:Liver / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D018962:Phlebotomy; D013103:Spherocytosis, Hereditary / Q000097:blood / Q000175:diagnosis* / Q000628:therapy; D014057:Tomography, X-Ray Computed
chemical_list: D005293:Ferritins
keywords: Anämie; Eisenstatus; Hämochromatose; Iron status; Serumferritin; anemia; hemochromatosis; serum ferritin