title: Cp*Co(III) -Catalyzed C(sp(3) )-H Bond Amidation of 8-Methylquinoline.
abstract: An efficient and external oxidant-free, Cp*Co(III) -catalyzed C(sp(3) )-H bond amidation of 8-methylquinoline, using oxazolone as an efficient amidating agent, is reported for the first time under mild conditions. The reaction is selective and tolerates a variety of functional groups. Based on previous reports and experimental results, the deprotonation pathway proceeds through an external base-assisted concerted metalation and deprotonation process.
authors.affiliation: Fine Chemical Laboratory, Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, India.
authors.forename: Nagaraju
authors.initials: N
authors.lastname: Barsu
authors.affiliation: Fine Chemical Laboratory, Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, India.
authors.forename: Md Atiur
authors.initials: MA
authors.lastname: Rahman
authors.affiliation: Fine Chemical Laboratory, Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, India.
authors.forename: Malay
authors.initials: M
authors.lastname: Sen
authors.affiliation: Fine Chemical Laboratory, Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208016, India. basker@iitk.ac.in.
authors.forename: Basker
authors.initials: B
authors.lastname: Sundararaju
keywords: amidation; cobalt; quinoline; sp3 C−H activation