title: Synthesis and In vitro Evaluation of Electrodeposited Barium Titanate Coating on Ti6Al4V.
abstract: Osseointegration has been the concern of implantology for many years. Researchers have used various ceramic coatings for this purpose; however, piezoelectric ceramics (e.g., barium titanate [BTO]) are a novel field of interest. In this regard, BTO (BaTiO3) coating was fabricated by electrophoretic deposition on Ti6Al4V medical alloy, using sol-gel-synthesized nanometer BTO powder. Structure and morphologies were studied using X-ray diffraction and scanning electron microscopy (SEM), respectively. Bioactivity response of coated samples was evaluated by SEM and inductively coupled plasma (ICP) analysis after immersion in simulated body fluid (SBF). Cell compatibility was also studied via MTT assay and SEM imaging. Results showed homogenous coating with cubic structure and crystallite size of about 41 nm. SEM images indicated apatite formation on the coating after 7 days of SBF immersion, and ICP analysis approved ions concentration decrement in SBF. Cells showed flattened morphology in intimate contact with coating after 7 days of culture. Altogether, coated samples demonstrated appropriate bioactivity and biocompatibility.
authors.affiliation: Department of Biomaterials, Nanotechnology and Tissue Engineering, School of Advanced Medical Technologies, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran.
authors.forename: Shahram
authors.initials: S
authors.lastname: Rahmati
authors.affiliation: Department of Materials Engineering, Isfahan University of Technology, Isfahan, 8415683111, Iran.
authors.forename: Mohammad Basir
authors.initials: MB
authors.lastname: Basiriani
authors.affiliation: Biosensor Research Center, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Rafienia
authors.affiliation: Department of Periodontology, School of Dentistry, Dental Implant Research Center, Isfahan University of Medical Sciences, Isfahan, 81744176, Iran.
authors.forename: Jaber
authors.initials: J
authors.lastname: Yaghini
authors.affiliation: Department of Materials Engineering, Isfahan University of Technology, Isfahan, 8415683111, Iran.
authors.forename: Keyvan
authors.initials: K
authors.lastname: Raeisi
keywords: Barium titanate; bioactivity; cytotoxicity; electrophoretic deposition; sol-gel