title: Active surveillance and safety organizational goals to reduce central line-associated bloodstream infections outside the intensive care unit: 9 years of experience.
abstract: We performed a quasi-experimental, cohort study in the medical-surgical inpatient wards comparing central line-associated bloodstream infection (CLABSI) rates and microbiologic characteristics in 3 phases. The CLABSI rates decreased 60% from phase 1 to 2 and 61.5% from phase 2 to 3. Gram-positive organisms were most frequently isolated in phases 1 and 3, and gram-negative bacilli were most frequently isolated in phase 2. The CLABSI surveillance and prevention program focusing on patient safety had a significant impact on CLABSI rates.
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil. Electronic address: helena.castagna@einstein.br.
authors.forename: H M F
authors.initials: HM
authors.lastname: Castagna
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: J Y
authors.initials: JY
authors.lastname: Kawagoe
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: P
authors.initials: P
authors.lastname: Gonçalves
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: F G
authors.initials: FG
authors.lastname: Menezes
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: A R
authors.initials: AR
authors.lastname: Toniolo
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: C V
authors.initials: CV
authors.lastname: Silva
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: M F S
authors.initials: MF
authors.lastname: Cardoso
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: C M
authors.initials: CM
authors.lastname: Santos
authors.affiliation: Albert Einstein Hospital, Morumbi, São Paulo, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Correa
mesh_terms: D016470:Bacteremia / Q000453:epidemiology / Q000517:prevention & control*; D055499:Catheter-Related Infections / Q000453:epidemiology / Q000517:prevention & control*; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D015331:Cohort Studies; D062665:Epidemiological Monitoring; D006090:Gram-Negative Bacteria / Q000302:isolation & purification; D006094:Gram-Positive Bacteria / Q000302:isolation & purification; D006801:Humans; D017053:Infection Control / Q000379:methods*; D007362:Intensive Care Units; D009937:Organizational Objectives; D061214:Patient Safety
keywords: Infection control; bundle; central line; central line–associated bloodstream infection; general medical wards; health care–associated infection; surveillance