title: Long-term clinical and radiological outcome of endovascular embolization of pancreatitis-related pseudoaneurysms.
abstract: Background Long-term outcome after embolization of pancreatitis-induced pseudoaneurysm is not yet determined. Purpose To assess the long-term efficacy and patients' overall survival after embolization of pancreatitis-induced pseudoaneurysm. Material and Methods Patients referred for endovascular treatment of a pancreatitis-induced pseudoaneurysm between January 1998 and January 2014 were analyzed. Embolization procedures were performed by transcatheter techniques using different types of embolic agents. Demographic, technical-radiological, and clinical data were collected. Results Thirty-four patients were identified with a pancreatitis-induced pseudoaneurysm; the underlying disease was acute (n = 13; 38%) or chronic (n = 21; 62%) pancreatitis; seven patients (20.6%) had active bleeding when embolized, while in the remaining 27 patients (79.4%) the pseudoaneurysm was not bleeding. In all 34 patients, successful endovascular exclusion of the pseudoaneurysm was obtained after the first attempt. Minor complications occurred in 11 patients (30%); no major complications were noted. A new pseudoaneurysm on a different vessel was identified during follow-up in three patients (9%). In another patient (3%), the excluded pseudoaneurysm reopened during follow-up. All four recurrences occurred within the first 5 months after embolization. Long-term follow-up (mean, 6.6 years; range, 4 months-16 years) revealed estimated survival rates of 94%, 89%, and 75% after 2, 5, and 10 years respectively, without pseudoaneurysm-related death. Conclusion Catheter-directed embolization of pancreatitis-induced pseudoaneurysms is relatively safe and effective. Recurrence or new pseudoaneurysm formation was low and occurred within the first 6 months after embolization. Overall survival is high, with no pseudoaneurysm-related deaths.
authors.affiliation: 1 Department of Radiology, University Hospitals Leuven, Belgium.
authors.forename: Ward
authors.initials: W
authors.lastname: Vander Mijnsbrugge
authors.affiliation: 2 Department of Hepatology, University Hospitals Leuven, Belgium.
authors.forename: Wim
authors.initials: W
authors.lastname: Laleman
authors.affiliation: 2 Department of Hepatology, University Hospitals Leuven, Belgium.
authors.forename: Werner
authors.initials: W
authors.lastname: Van Steenbergen
authors.affiliation: 1 Department of Radiology, University Hospitals Leuven, Belgium.
authors.forename: Sam
authors.initials: S
authors.lastname: Heye
authors.affiliation: 2 Department of Hepatology, University Hospitals Leuven, Belgium.
authors.forename: Chris
authors.initials: C
authors.lastname: Verslype
authors.affiliation: 1 Department of Radiology, University Hospitals Leuven, Belgium.
authors.forename: Geert
authors.initials: G
authors.lastname: Maleux
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017541:Aneurysm, False / Q000209:etiology* / Q000628:therapy*; D004621:Embolization, Therapeutic / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D010195:Pancreatitis / Q000150:complications*; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: Interventional radiology; endovascular; pancreatitis; pseudoaneurysm