title: Anterior Maxilla Augmentation Using Palatal Bone Block with Platelet-Rich Fibrin: A Controlled Trial.
abstract: OBJECTIVE
  This study was conducted to characterize clinically and radiographically the effect of using platelet-rich fibrin (PRF) autologous graft on the augmentation results of autogenous palatal bone blocks.
  
  
  METHODS
  Patients who suffered from horizontal alveolar bone defects in the anterior maxillary ridge (≤ 4.5 mm) with one or two missing teeth were augmented with autogenous palatal bone blocks 4 months prior to implant placement. PRF was used to cover the block in the test group, while only the block was used in the control. Bone width was measured with a manual caliper preaugmentation (t0), and at 0 (t1) and 4 months (t2). Cone beam computed tomography (CBCT) scans were performed at t0 and t2. Nonparametric tests (Mann-Whitney, Friedman's, and Wilcoxon signed-rank tests) were used for the comparisons. The significance level was set at P ≤ .05.
  
  
  RESULTS
  In the 14 sites (12 patients), all but one autograft (from the control group) integrated successfully after 4 months. No statistically significant difference was found between demographic data in the two groups. There was a statistically significant increase in the buccopalatal bone width in both groups by time as measured by CBCT as well as the manual caliper. The test group showed statistically significantly lower mean graft resorption than the control group (test, 0.8 ± 0.6 mm; control, 1.6 ± 0.9 mm; P = .006).
  
  
  CONCLUSIONS
  Autogenous palatal bone block surface resorption is significantly decreased by the use of PRF coverage.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Moussa
authors.forename: Omnia Abou
authors.initials: OA
authors.lastname: El-Dahab
authors.forename: Hani
authors.initials: H
authors.lastname: El Nahass
mesh_terms: D000293:Adolescent; D000328:Adult; D000539:Alveolar Process / Q000601:surgery; D000540:Alveolar Ridge Augmentation / Q000379:methods*; D016025:Bone Transplantation / Q000379:methods*; D054893:Cone-Beam Computed Tomography / Q000379:methods; D005260:Female; D005337:Fibrin / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D008437:Maxilla / Q000601:surgery*; D008875:Middle Aged; D053657:Platelet-Rich Plasma; D014182:Transplantation, Autologous; D055815:Young Adult
chemical_list: D005337:Fibrin