title: Diversity of beta-papillomavirus at anogenital and oral anatomic sites of men: The HIM Study.
abstract: Our goal was to describe prevalence of β-HPVs at three anatomic sites among 717 men from Brazil, Mexico and US enrolled in the HPV Infection in Men (HIM) Study. β-HPVs were genotyped using Luminex technology. Overall, 77.7%, 54.3% and 29.3% men were positive for any β-HPV at the genitals, anal canal, and oral cavity, respectively. Men from US and Brazil were significantly less likely to have β-HPV at the anal canal than men from Mexico. Older men were more likely to have β-HPV at the anal canal compared to younger men. Prevalence of β-HPV at the oral cavity was significantly associated with country of origin and age. Current smokers were significantly less likely to have β-HPV in the oral cavity than men who never smoked. Lack of associations between β-HPV and sexual behaviors may suggest other routes of contact such as autoinoculation which need to be explored further.
authors.affiliation: Molecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
authors.forename: Emily Montosa
authors.initials: EM
authors.lastname: Nunes
authors.affiliation: Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors.forename: Staci L
authors.initials: SL
authors.lastname: Sudenga
authors.affiliation: Infections and Cancer Biology Group, International Agency for Cancer Research (IARC), Lyon, France.
authors.forename: Tarik
authors.initials: T
authors.lastname: Gheit
authors.affiliation: Infections and Cancer Biology Group, International Agency for Cancer Research (IARC), Lyon, France.
authors.forename: Massimo
authors.initials: M
authors.lastname: Tommasino
authors.affiliation: Molecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
authors.forename: Maria Luiza
authors.initials: ML
authors.lastname: Baggio
authors.affiliation: Molecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
authors.forename: Silvaneide
authors.initials: S
authors.lastname: Ferreira
authors.affiliation: Ludwig Institute for Cancer Research, São Paulo branch, São Paulo, Brazil.
authors.forename: Lenice
authors.initials: L
authors.lastname: Galan
authors.affiliation: Centro de Referência e Treinamento DST/Aids, São Paulo, Brazil.
authors.forename: Roberto C
authors.initials: RC
authors.lastname: Silva
authors.affiliation: Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors.forename: Christine M
authors.initials: CM
authors.lastname: Pierce Campbell
authors.affiliation: Centro de Investigación en Salud Poblacional, Instituto Nacional de Salud Pública, Cuernavaca, Mexico.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Lazcano-Ponce
authors.affiliation: Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.
authors.forename: Anna R
authors.initials: AR
authors.lastname: Giuliano
authors.affiliation: Molecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil; Department of Radiology and Oncology, School of Medicine, University of São Paulo, São Paulo, Brazil.
authors.forename: Luisa L
authors.initials: LL
authors.lastname: Villa
authors.affiliation: Molecular Biology Laboratory, Center for Translational Research in Oncology, Instituto do Câncer do Estado de São Paulo, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil. Electronic address: laura.sichero@hc.fm.usp.br.
authors.forename: Laura
authors.initials: L
authors.lastname: Sichero
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001003:Anal Canal / Q000821:virology*; D052686:Betapapillomavirus / Q000145:classification* / Q000235:genetics; D001938:Brazil / Q000453:epidemiology; D004279:DNA, Viral; D005260:Female; D005837:Genitalia, Male / Q000821:virology*; D005838:Genotype; D006801:Humans; D008297:Male; D008875:Middle Aged; D009055:Mouth / Q000821:virology*; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000821:virology*; D011159:Population Surveillance; D015995:Prevalence; D012307:Risk Factors; D012725:Sexual Behavior; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D004279:DNA, Viral
keywords: Anogenital; Cutaneous human papillomavirus; HIM Study; Males; Oral; Prevalence