title: High-frequency (13.56-MHz) and ultrahigh-frequency (915-MHz) radio identification systems do not affect platelet activation and functions.
abstract: In radiofrequency identification (RFID) systems used in labeling of blood components, blood cells are subjected to the direct influence of electromagnetic waves throughout the storage period. The aim of this study was to prove the safety of storage of platelet concentrates (PCs) in containers labeled with RFID tags.
  
  
  
  Ten pooled PCs obtained from 12 buffy coats each suspended in additive solution were divided into three separate containers that were assigned to three groups: control, PCs labeled with ultrahigh frequency (UHF) range tags and exposed to 915-MHz radio waves, and PCs labeled with high-frequency (HF) range tags and exposed to 13.56-MHz radio waves. PCs were stored at 20 to 24°C for 7 days. In vitro tests of platelet (PLT) function were performed on the first, fifth, and seventh days of storage.
  
  
  
  There were no significant differences in pH; hypotonic shock resistance; surface expression of CD62P, CD42a, or CD63; release of PLT-derived microparticles; PLT aggregation; and number of PLTs between PCs stored at a constant exposure to radio waves of two different frequencies and the control group on the first, fifth, and seventh days of storage.
  
  
  
  The results of the study indicate no impact of electromagnetic radiation generated in HF and UHF RFID systems and constant contact with the tags on the quality of stored PCs.
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Rogowska
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.
authors.forename: Anna Małgorzata
authors.initials: AM
authors.lastname: Chabowska
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.
authors.forename: Alina
authors.initials: A
authors.lastname: Lipska
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.
authors.forename: Barbara
authors.initials: B
authors.lastname: Boczkowska-Radziwon
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.
authors.forename: Magdalena
authors.initials: M
authors.lastname: Bujno
authors.affiliation: Department of Physical Chemistry and the , Medical University of Bialystok, Bialystok, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Rusak
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.|Department of Hematology, Medical University of Bialystok, Bialystok, Poland.
authors.forename: Mateusz
authors.initials: M
authors.lastname: Dziemianczuk
authors.affiliation: Regional Centre for Transfusion Medicine and the , Medical University of Bialystok, Bialystok, Poland.|Department of Hematology, Medical University of Bialystok, Bialystok, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Radziwon
mesh_terms: D001792:Blood Platelets / Q000528:radiation effects; D001793:Blood Preservation; D058731:Blood Safety; D055252:Cell-Derived Microparticles; D006801:Humans; D006863:Hydrogen-Ion Concentration; D019007:P-Selectin / Q000032:analysis; D015539:Platelet Activation / Q000528:radiation effects*; D010979:Platelet Function Tests; D019038:Platelet Glycoprotein GPIb-IX Complex / Q000032:analysis; D057233:Radio Frequency Identification Device; D060149:Tetraspanin 30 / Q000032:analysis; D013997:Time Factors
chemical_list: D019007:P-Selectin; D019038:Platelet Glycoprotein GPIb-IX Complex; D060149:Tetraspanin 30