title: [Italian validation of the Chemotherapy Induced Taste Alteration Scale].
abstract: . Italian validation of the Chemotherapy Induced Taste Alteration Scale. Introdution. Taste alterations (TAs) are an underestimated side effect despite affecting 75% of chemo-radiotherapy patients. TAs may cause discomfort and food aversions up to loss of appetite and anorexia. The available instruments do not discriminate the different types of TAs.
  
  
  OBJECTIVE
  The aim of the study is to validate the Italian version of CiTAS, a 18-items scale that assesses specific TAs, symptoms of discomfort and their impact on patient nutrition.
  
  
  METHODS
  A convenience sample of 243 patients with chemotherapy-induced taste alterations were enrolled. Data were analyzed for item consistency using Cronbach alpha and construct validity using factor analysis.
  
  
  RESULTS
  The factor analysis identified four dimensions that explained a total variance of 67%: decline in basic taste, discomfort, phantogeusia and parageusia, and general taste alterations. The scale showed good validity (Cronbach's alpha = 0.82).
  
  
  CONCLUSIONS
  The CiTAS enabled the valid and reliable measurement of specific symptoms of chemotherapy-induced TAs. It can be used both as a clinical tool and in future studies to evaluate the effectiveness of specific TAs treatments.
authors.forename: Sara
authors.initials: S
authors.lastname: Campagna
authors.forename: Silvia
authors.initials: S
authors.lastname: Gonella
authors.forename: Maddalena
authors.initials: M
authors.lastname: Stuardi
authors.forename: Riccardo
authors.initials: R
authors.lastname: Sperlinga
authors.forename: Michele
authors.initials: M
authors.lastname: Cerponi
authors.forename: Monica
authors.initials: M
authors.lastname: Olivero
authors.forename: Piero Luigi
authors.initials: PL
authors.lastname: Giuliano
authors.forename: Rosella
authors.initials: R
authors.lastname: Marchese
authors.forename: Elisa
authors.initials: E
authors.lastname: Carnovali
authors.forename: Roberta
authors.initials: R
authors.lastname: Pedersini
authors.forename: Paola
authors.initials: P
authors.lastname: Berchialla
authors.forename: Valerio
authors.initials: V
authors.lastname: Dimonte
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000970:Antineoplastic Agents / Q000009:adverse effects*; D059026:Diagnostic Self Evaluation; D005260:Female; D006801:Humans; D007558:Italy; D008297:Male; D008875:Middle Aged; D063189:Symptom Assessment; D013651:Taste Disorders / Q000139:chemically induced* / Q000175:diagnosis*; D055815:Young Adult
chemical_list: D000970:Antineoplastic Agents