title: Clinicopathological analysis of 384 cases of poroid neoplasms including 98 cases of apocrine type cases.
abstract: We examined 384 cases of poroid neoplasms. Most cases (n = 279, 72.7%) exhibited the features of only one subtype. One hundred and ninety-eight cases (51.6%) showed only the features of poroma (P), 20 (5.2%) hidroacanthoma simplex (HS), five (1.3%) dermal duct tumor (D) and 56 (14.6%) hidradenoma (HA). Composite tumors of those four subtypes were observed in 105 cases (27.3%). In the trunk and lower extremities, lesions with the features of P were observed at higher rates than other sites. Those of HS and D were more frequently observed in the lower extremities. Those of HA were seen at higher rates in the scalp, face, neck and genitalia. Ninety-eight cases (25.5%) showed decapitation secretion and diagnosed as apocrine type lesion. Apocrine type lesions were frequently observed in the lesions on the genitalia (40.0%), scalp (31.8%) and trunk (31.1%), whereas at lower rates in those on the neck (21.4%) and lower extremities (24.0%). In apocrine type cases, the lesions were located more frequently on the scalp and trunk than non-apocrine type, whereas were less frequent on extremities. The rate of apocrine type lesions in the cases with only one subtype (19.7%) was lower than that of those with composite tumors (41.0%). In the apocrine type (43.9%), composite tumors are more frequent than in the non-apocrine type (21.7%). In D (40.8%) and HA (32.3%), apocrine type lesions were more frequently observed than other subtypes. In conclusion, it should be noted that a quarter of poroid neoplasms are composite tumors and/or show apocrine differentiation.
authors.affiliation: Department of Dermatology, The Jikei University School of Medicine, Tokyo, Japan.
authors.forename: Keigo
authors.initials: K
authors.lastname: Ito
authors.affiliation: Division of Dermatology, Nippon Medical School Musashi Kosugi Hospital, Kanagawa, Japan.
authors.forename: Shin-Ichi
authors.initials: SI
authors.lastname: Ansai
authors.affiliation: Sapporo Institute for Dermatopathology, Hokkaido, Japan.
authors.forename: Takaya
authors.initials: T
authors.lastname: Fukumoto
authors.affiliation: Sapporo Institute for Dermatopathology, Hokkaido, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Anan
authors.affiliation: Sapporo Institute for Dermatopathology, Hokkaido, Japan.
authors.forename: Tetsunori
authors.initials: T
authors.lastname: Kimura
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D057091:Poroma / Q000473:pathology*; D013544:Sweat Gland Neoplasms / Q000473:pathology*
keywords: apocrine type poroid neoplasms; dermal duct tumor; hidroacanthoma simplex; poroid hidradenoma; poroma