title: Pharmaceutical crystallization with nanocellulose organogels.
abstract: Carboxylated nanocellulose forms organogels at 0.3 wt% in the presence of a cationic surfactant. The resulting gels can be used as novel crystallization media for pharmaceutical solid form control, resulting in isolation a new sulfapyridine solvate, morphology modification and crystallization of an octadecylammonium salt of sulfamethoxazole.
authors.affiliation: Department of Analytical Chemistry, University of Córdoba, Marie Curie Building, Campus de Rabanales, E-14071 Córdoba, Spain. qa1vacam@uco.es.
authors.forename: Celia
authors.initials: C
authors.lastname: Ruiz-Palomero
authors.affiliation: Department of Chemistry, Durham University, University Science Laboratories, South Road, Durham, DH1 3LE, UK. jon.steed@durham.ac.uk.
authors.forename: Stuart R
authors.initials: SR
authors.lastname: Kennedy
authors.affiliation: Department of Analytical Chemistry, University of Córdoba, Marie Curie Building, Campus de Rabanales, E-14071 Córdoba, Spain. qa1vacam@uco.es.
authors.forename: M Laura
authors.initials: ML
authors.lastname: Soriano
authors.affiliation: Department of Chemistry, Durham University, University Science Laboratories, South Road, Durham, DH1 3LE, UK. jon.steed@durham.ac.uk.
authors.forename: Christopher D
authors.initials: CD
authors.lastname: Jones
authors.affiliation: Department of Analytical Chemistry, University of Córdoba, Marie Curie Building, Campus de Rabanales, E-14071 Córdoba, Spain. qa1vacam@uco.es.
authors.forename: Miguel
authors.initials: M
authors.lastname: Valcárcel
authors.affiliation: Department of Chemistry, Durham University, University Science Laboratories, South Road, Durham, DH1 3LE, UK. jon.steed@durham.ac.uk.
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Steed
mesh_terms: D002412:Cations / Q000737:chemistry; D002482:Cellulose / Q000737:chemistry*; D003460:Crystallization; D018360:Crystallography, X-Ray; D005782:Gels / Q000737:chemistry*; D008958:Models, Molecular; D053758:Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D013420:Sulfamethoxazole / Q000737:chemistry*; D013501:Surface-Active Agents / Q000737:chemistry
chemical_list: D002412:Cations; D005782:Gels; D013501:Surface-Active Agents; D002482:Cellulose; D013420:Sulfamethoxazole