title: Open partial nephrectomy in renal cell cancer - Essential or obsolete?
abstract: Since the first partial nephrectomy was first conducted 131 years ago, the procedure has evolved into the gold standard treatment for small renal masses. Over the past decade, with the introduction of minimally invasive surgery, open partial nephrectomy still retains a valuable role in the treatment of complex tumours in challenging clinical situations (e.g. hereditary renal cancer or single kidneys), and enables surgeons to push the boundaries of nephron-sparing surgery. In this article, we consider the origin of the procedure and how it has evolved over the past century, the surgical techniques involved, and the oncological and functional outcomes.
authors.affiliation: Department of Urology, Guy's and St Thomas NHS Foundation Trust, London, UK. Electronic address: eleniana@gmail.com.
authors.forename: Eleni
authors.initials: E
authors.lastname: Anastasiadis
authors.affiliation: Department of Urology, Guy's and St Thomas NHS Foundation Trust, London, UK.
authors.forename: Timothy
authors.initials: T
authors.lastname: O'Brien
authors.affiliation: Department of Urology, Guy's and St Thomas NHS Foundation Trust, London, UK.
authors.forename: Archana
authors.initials: A
authors.lastname: Fernando
mesh_terms: D002292:Carcinoma, Renal Cell / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D009392:Nephrectomy / Q000379:methods*; D016896:Treatment Outcome; D047368:Tumor Burden
keywords: Nephron-sparing surgery; Open partial nephrectomy; Renal cancer; Small renal masses