title: The timing of breast and axillary surgery after neoadjuvant chemotherapy for breast cancer.
abstract: Neoadjuvant chemotherapy (NAC) has traditionally been used in locally advanced and inflammatory breast cancer, allowing for a reduction in disease volume and therefore optimizing surgical resection of disease in the breast. NAC impacts both the tumor in the breast and the lymph nodes and may allow for the option of breast-conserving surgery and avoiding an axillary dissection. The aim of this review is to discuss the considerations and timing of surgical treatment of the breast and the axilla following NAC in patients with breast cancer.
authors.affiliation: Department of Surgery, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: Zahraa
authors.initials: Z
authors.lastname: Al-Hilli
authors.affiliation: Department of Surgery, Mayo Clinic, 200 First Street, Rochester, MN 55905, USA. Email: Boughey.Judy@mayo.edu.
authors.forename: Judy C
authors.initials: JC
authors.lastname: Boughey
mesh_terms: D001943:Breast Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery*; D017024:Chemotherapy, Adjuvant; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy; D016032:Randomized Controlled Trials as Topic
keywords: Breast cancer; neoadjuvant therapy (NAC)