title: New Tracers PET in Head and Neck Squamous Cell Carcinoma.
abstract: PET is commonly used in the evaluation and posttreatment management of head and neck squamous cell carcinoma. Although [(18)F]fluorodeoxyglucose is the most commonly used radiopharmaceutical, many other radiopharmaceuticals are under investigation to assess particular biologic characteristics such as hypoxia and tumor repopulation. In this review, the authors discuss new PET tracers that allow the biologic profiling of head and neck squamous cell carcinomas, including [(18)F]fluoromisonidazole, [(18)F]fluorothymidine, [(18)F]fluoromethyltyrosine, and epidermal growth factor receptor biomarkers.
authors.affiliation: Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, 622 West 168th Street, New York, NY 10032, USA.
authors.forename: Tony J C
authors.initials: TJ
authors.lastname: Wang
authors.affiliation: Department of Radiology, University of Iowa, 200 Hawkins Drive, Iowa City, IA, USA.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Menda
authors.affiliation: Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, 622 West 168th Street, New York, NY 10032, USA.
authors.forename: Simon K
authors.initials: SK
authors.lastname: Cheng
authors.affiliation: Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University, 622 West 168th Street, New York, NY 10032, USA.
authors.forename: Cheng-Chia
authors.initials: CC
authors.lastname: Wu
authors.affiliation: Department of Radiation Oncology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA. Electronic address: leen2@mskcc.org.
authors.forename: Nancy Y
authors.initials: NY
authors.lastname: Lee