title: [Cutaneous leishmaniasis due to Leishmania infantum associated with HIV].
abstract: BACKGROUND
  In Senegal, reported cases of cutaneous leishmaniasis are often due to Leishmania major. Immunosuppression related to HIV infection contributes to the emergence of leishmaniasis in humans and to cutaneous localization of viscerotropic species. We report the first observed case in Senegal of opportunistic cutaneous leishmaniasis due to Leishmania infantum associated with HIV.
  
  
  METHODS
  A 5-year-old boy presented crusted ulcerative lesions of the scalp and left forearm, together with axillary and cervical lymphadenopathy present for two months. Direct parasitological examination of the scalp and arm lesions, coupled with liquid aspiration of lymph nodes and bone marrow, enabled identification of amastigote forms of Leishmania. Polymerase chain reaction performed on skin, lymph node and bone marrow biopsy samples allowed identification of L. infantum. The child was positive for HIV1. Treatment of HIV infection and leishmaniasis resulted in clinical improvement.
  
  
  CONCLUSIONS
  Co-infection with cutaneous leishmaniasis due to L. infantum and HIV is a complex combination in terms of the related therapeutic issues. The clinical and laboratory outcomes depend on restoration of immunity and on the efficacy, safety and availability of anti-leishmaniasis drugs.
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal. Electronic address: ahydiatta@yahoo.com.
authors.forename: B-A
authors.initials: BA
authors.lastname: Diatta
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: M
authors.initials: M
authors.lastname: Diallo
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: S
authors.initials: S
authors.lastname: Diadie
authors.affiliation: Service de parasitologie-mycologie, faculté de médecine et pharmacie, université Cheikh Anta Diop, BP 5005, Dakar-Fann, Sénégal.
authors.forename: B
authors.initials: B
authors.lastname: Faye
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: M
authors.initials: M
authors.lastname: Ndiaye
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: H
authors.initials: H
authors.lastname: Hakim
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: S
authors.initials: S
authors.lastname: Diallo
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: B
authors.initials: B
authors.lastname: Seck
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: S-O
authors.initials: SO
authors.lastname: Niang
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: A
authors.initials: A
authors.lastname: Kane
authors.affiliation: Service de dermatologie, hôpital Aristide Le Dantec, 30, avenue Pasteur, BP 3001, Dakar, Sénégal.
authors.forename: M-T
authors.initials: MT
authors.lastname: Dieng
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000175:diagnosis*; D002675:Child, Preschool; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D018314:Leishmania infantum / Q000302:isolation & purification*; D016773:Leishmaniasis, Cutaneous / Q000150:complications / Q000175:diagnosis*; D008297:Male; D012675:Senegal
keywords: Child; Cutaneous leishmaniasis; Enfant; HIV; Leishmania infantum; Leishmaniose cutanée; Senegal; Sénégal; VIH