title: (18)F-Fluoride PET and PET/CT Imaging of Skeletal Metastases.
abstract: (18)F-fluoride is a bone-specific PET tracer that was first described 40 years ago, but it has been more extensively investigated in the setting of bone metastases only in more recent years. (18)F-fluoride PET is a highly sensitive method for detecting bone metastases in many cancers, and the use of (18)F-fluoride with hybrid PET/computed tomography (CT) further improves specificity with the additional morphologic information available from the CT component. (18)F-fluoride provides complementary information to tumor-specific PET tracers, and it is likely that this imaging method will continue to be used more routinely and for newer applications to grow.
authors.affiliation: Department of Nuclear Medicine and PET, The Royal Marsden NHS Foundation Trust, Downs Road, Sutton SM2 5PT, UK. Electronic address: gcook@icr.ac.uk.
authors.forename: Gary J R
authors.initials: GJ
authors.lastname: Cook
keywords: (18)F-fluoride; Positron emission tomography; Skeletal metastases