title: On the accuracy of dose prediction near metal fixation devices for spine SBRT.
abstract: The metallic fixations used in surgical procedures to support the spine mechani-cally usually consist of high-density materials. Radiation therapy to palliate spinal cord compression can include prophylactic inclusion of potential tumor around the site of such fixation devices. Determination of the correct density and shape of the spine fixation device has a direct effect on the dose calculation of the radiation field. Even with the application of modern computed tomography (CT), under- or overestimation of dose, both immediately next to the device and in the surround-ing tissues, can occur due to inaccuracies in the dose prediction algorithm. In this study, two commercially available dose prediction algorithms (Eclipse AAA and ACUROS), EGSnrc Monte Carlo, and GAFchromic film measurements were com-pared for a clinical spine SBRT case to determine their accuracy. An open six-field plan and a clinical nine-field IMRT plan were applied to a phantom containing a metal spine fixation device. Dose difference and gamma analysis were performed in and around the tumor region adjacent to the fixation device. Dose calculation inconsistency was observed in the open field plan. However, in the IMRT plan, the dose perturbation effect was not observed beyond 5 mm. Our results suggest that the dose effect of the metal fixation device to the spinal cord and the tumor volume is not observable, and all dose calculation algorithms evaluated can provide clinically acceptable accuracy in the case of spinal SBRT, with the tolerance of 95% for gamma criteria of 3%/3 mm.
authors.affiliation: University of Sydney. 123@123.com.
authors.forename: Zhangkai J
authors.initials: ZJ
authors.lastname: Cheng
authors.forename: Regina M
authors.initials: RM
authors.lastname: Bromley
authors.forename: Brad
authors.initials: B
authors.lastname: Oborn
authors.forename: Martin
authors.initials: M
authors.lastname: Carolan
authors.forename: Jeremy T
authors.initials: JT
authors.lastname: Booth
mesh_terms: D000465:Algorithms; D003198:Computer Simulation; D006801:Humans; D008670:Metals / Q000737:chemistry*; D009010:Monte Carlo Method; D019047:Phantoms, Imaging; D016634:Radiosurgery / Q000295:instrumentation* / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*; D013125:Spinal Neoplasms / Q000601:surgery*; D014057:Tomography, X-Ray Computed
chemical_list: D008670:Metals