title: Preliminary phytochemical screening, Antibacterial potential and GC-MS analysis of two medicinal plant extracts.
abstract: The presence study was aimed to catalyze the primary metabolites and their confirmation by using GC-MS analysis and antibacterial potential of leaf extract of two important medicinal plant viz., Eucalyptus and Azadirachta indica. The antibacterial potential of the methanol leaf extract of the studied species was tested against Escherichia coli, Pseudomonas aeruginosa, Klebsiellap neumoniae, Streptococcus pyogens, Staphylococcus aureus using by agar well diffusion method. The higher zone of inhibition (16mm) was observed against the bacterium Pseudomonas aeruginosa at 100μl concentration of methanol leaf extract. Preliminary phytochemical analysis of studied species shows that presence of phytochemical compounds like steroids, phenolic compounds and flavonoids. GC-MS analysis confirms the occurrence of 20 different compounds in the methanol leaf extract of the both studied species.
authors.affiliation: School of Energy Environment and Natural Resources, Madurai Kamaraj University, Madurai, India.
authors.forename: Seerangaraj
authors.initials: S
authors.lastname: Vijayaram
authors.affiliation: School of Energy Environment and Natural Resources, Madurai Kamaraj University, Madurai, India.
authors.forename: Suruli
authors.initials: S
authors.lastname: Kannan
authors.affiliation: School of Biotechnology, Madurai Kamaraj University, Madurai, India.
authors.forename: Konda Mani
authors.initials: KM
authors.lastname: Saravanan
authors.affiliation: PG & Research Department of Microbiology, Hindusthan College of Arts and Science, Coimbatore, India.
authors.forename: Seerangaraj
authors.initials: S
authors.lastname: Vasantharaj
authors.affiliation: PG & Research Department of Microbiology, Hindusthan College of Arts and Science, Coimbatore, India.
authors.forename: Selvam
authors.initials: S
authors.lastname: Sathiyavimal
authors.affiliation: PG & Research Department of Biotechnology, Hindusthan College of Arts and Science, Coimbatore, India.
authors.forename: Palanisamy Senthilkumar
authors.initials: PS
authors.lastname: P
mesh_terms: D000900:Anti-Bacterial Agents / Q000302:isolation & purification / Q000494:pharmacology*; D031601:Azadirachta / Q000737:chemistry*; D001419:Bacteria / Q000187:drug effects* / Q000254:growth & development; D052978:Disk Diffusion Antimicrobial Tests; D005052:Eucalyptus / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D000432:Methanol / Q000737:chemistry; D064209:Phytochemicals / Q000302:isolation & purification / Q000494:pharmacology*; D008517:Phytotherapy; D010936:Plant Extracts / Q000302:isolation & purification / Q000494:pharmacology*; D018515:Plant Leaves; D010946:Plants, Medicinal; D012997:Solvents / Q000737:chemistry
chemical_list: D000900:Anti-Bacterial Agents; D064209:Phytochemicals; D010936:Plant Extracts; D012997:Solvents; D000432:Methanol