title: Nocturia and prevalence of erectile dysfunction in Japanese patients with type 2 diabetes mellitus: The Dogo Study.
abstract: OBJECTIVE
  Several epidemiological studies have reported a positive association between nocturia and erectile dysfunction (ED). Yet only limited evidence exists regarding the association between nocturia and ED among patients with type 2 diabetes mellitus, although nocturia and ED are common among type 2 diabetes mellitus patients.
  
  
  METHODS
  Study participants were 332 male Japanese patients with type 2 diabetes mellitus, aged 19-70 years, who had undergone blood tests at our institutions. A self-administered questionnaire was used to collect information on the variables under study. Adjustment was made for age, body mass index, hypertension, stroke, ischemic heart disease, glycated hemoglobin and diabetic neuropathy. ED, moderate to severe ED and severe ED were defined as present when a participant had a Sexual Health Inventory for Men score <22, <12 and <8, respectively. Study participants were considered to have nocturia if they answered 'once or more' to the question: 'Within 1 week, how many times do you typically wake up to urinate from sleeping at night until waking in the morning?'
  
  
  RESULTS
  The prevalence of nocturia was 79.8%. Nocturia was independently positively associated with ED and moderate to severe ED: the adjusted odds ratios were 7.86 (95% confidence interval 2.11-33.56) and 2.17 (95% confidence interval 1.16-4.12), respectively. The positive association between nocturia and severe ED fell just short of significance.
  
  
  CONCLUSIONS
  In Japanese men with type 2 diabetes mellitus, nocturia might be associated with ED and moderate to severe ED.
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Toon, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Furukawa
authors.affiliation: Department of Internal Medicine, Yawatahama General City Hospital, Yawatahama, Japan.
authors.forename: Takenori
authors.initials: T
authors.lastname: Sakai
authors.affiliation: Department of Internal Medicine, Matsuyama Shimin Hospital, Matsuyama, Japan.
authors.forename: Tetsuji
authors.initials: T
authors.lastname: Niiya
authors.affiliation: Department of Internal Medicine, Saiseikai Matsuyama Hospital, Matsuyama, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Miyaoka
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Teruki
authors.initials: T
authors.lastname: Miyake
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Yamamoto
authors.affiliation: Department of Public Health, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Koutatsu
authors.initials: K
authors.lastname: Maruyama
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Toon, Japan.
authors.forename: Keiko
authors.initials: K
authors.lastname: Tanaka
authors.affiliation: Department of Internal Medicine, Ehime Prefectural Central Hospital, Matsuyama, Japan.
authors.forename: Teruhisa
authors.initials: T
authors.lastname: Ueda
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Hidenori
authors.initials: H
authors.lastname: Senba
authors.affiliation: Department of Internal Medicine, Saiseikai Saijo Hospital, Saijo, Japan.
authors.forename: Masamoto
authors.initials: M
authors.lastname: Torisu
authors.affiliation: Department of Internal Medicine, Ehime Niihama Hospital, Niihama, Japan.
authors.forename: Hisaka
authors.initials: H
authors.lastname: Minami
authors.affiliation: Department of Internal Medicine, Saiseikai Imabari Hospital, Imabari, Japan.
authors.forename: Morikazu
authors.initials: M
authors.lastname: Onji
authors.affiliation: Department of Public Health, Juntendo University School of Medicine, Tokyo, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Tanigawa
authors.affiliation: Department of Lifestyle-related Medicine and Endocrinology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Bunzo
authors.initials: B
authors.lastname: Matsuura
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Toon, Japan.
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hiasa
authors.affiliation: Department of Epidemiology and Preventive Medicine, Ehime University Graduate School of Medicine, Toon, Japan.|Epidemiology and Medical Statistics Unit, Translational Research Center, Ehime University Hospital, Toon, Japan.
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Miyake
mesh_terms: D000328:Adult; D000368:Aged; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology*; D007172:Erectile Dysfunction / Q000150:complications / Q000453:epidemiology*; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D053158:Nocturia / Q000150:complications / Q000453:epidemiology*; D015995:Prevalence; D055815:Young Adult
keywords: Diabetes; Erectile dysfunction; Nocturia