title: A protracted course of Pneumocystis pneumonia in the setting of an immunosuppressed child with GMS-negative bronchoalveolar lavage.
abstract: We report a case of Pneumocystis pneumonia in a 5-year-old male with Trisomy 21 and acute lymphoblastic leukemia. The lack of response to trimethoprim-sulfamethoxazole raised concerns for antimicrobial resistance. Further, diagnosis of Pneumocystis in this patient was complicated by a GMS-negative bronchoalveolar lavage despite molecular evidence of Pneumocystis infection.
authors.affiliation: University of Pittsburgh, RK Mellon Institute for Pediatric Research, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, United States.
authors.forename: Taylor
authors.initials: T
authors.lastname: Eddens
authors.affiliation: Pediatric Infectious Diseases and Immunology, Host Defense Program, Nationwide Children's Hospital and The Ohio State University, Columbus, OH 43205, United States.
authors.forename: Eunkyung
authors.initials: E
authors.lastname: Song
authors.affiliation: Pediatric Infectious Diseases and Immunology, Host Defense Program, Nationwide Children's Hospital and The Ohio State University, Columbus, OH 43205, United States.
authors.forename: Monica I
authors.initials: MI
authors.lastname: Ardura
authors.affiliation: University of Pittsburgh, RK Mellon Institute for Pediatric Research, Children's Hospital of Pittsburgh of UPMC, Pittsburgh, PA 15224, United States.
authors.forename: Jay K
authors.initials: JK
authors.lastname: Kolls
keywords: Antimicrobial resistance; GMS diagnosis; Life cycle; Pneumocystis