title: Lens Position Parameters as Predictors of Intraocular Pressure Reduction After Cataract Surgery in Glaucomatous Versus Nonglaucomatous Eyes.
abstract: To evaluate the relationship between lens position parameters and intraocular pressure (IOP) reduction after cataract surgery in patients with primary open-angle glaucoma (POAG) and in nonglaucomatous patients.
  
  
  
  The main outcomes of this prospective study were percent and absolute IOP change, which were calculated using the preoperative IOP and the IOP 4 months after cataract surgery in POAG and nonglaucomatous eyes. Lens position (LP), defined as anterior chamber depth (ACD) + one-half lens thickness (LT), was assessed preoperatively using parameters from optical biometry. Preoperative IOP, axial length (AL), ACD, LT, relative lens position (RLP), and the ratio of preoperative IOP to ACD (PD ratio) were also evaluated as potential predictors of IOP change.
  
  
  
  Four months postoperatively, the average IOP reduction was 2.80 ± 3.83 mm Hg (15.79%) from the preoperative mean of 14.73 ± 2.89 mm Hg for nonglaucomatous eyes. The average IOP reduction was 2.66 ± 2.07 mm Hg (16.98%) from the preoperative mean of 14.86 ± 2.97 mm Hg for POAG eyes. Preoperative IOP, sex, AL, ACD, PD ratio, and LP predicted IOP change in nonglaucomatous eyes. Preoperative IOP and PD ratio predicted IOP change in POAG eyes.
  
  
  
  Intraocular pressure reduction after phacoemulsification cataract surgery in nonglaucomatous eyes is significantly greater in more anteriorly positioned lenses. Though it did not reach statistical significance in patients with glaucoma, the association of LP with IOP reduction is in the same direction as in nonglaucomatous patients where smaller LP appears to predict greater IOP reduction. Lens position is a simple, easily calculable, accurate, and widely available parameter, which clinicians can potentially utilize in managing glaucoma.
authors.affiliation: Department of Ophthalmology University of California-San Francisco, San Francisco, California, United States.
authors.forename: Paul
authors.initials: P
authors.lastname: Coh
authors.affiliation: Department of Ophthalmology University of California-San Francisco, San Francisco, California, United States 2Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Sasan
authors.initials: S
authors.lastname: Moghimi
authors.affiliation: Department of Ophthalmology University of California-San Francisco, San Francisco, California, United States 3Case Western Reserve University School of Medicine, Cleveland, Ohio, United States.
authors.forename: Rebecca I
authors.initials: RI
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology University of California-San Francisco, San Francisco, California, United States 4Department of Ophthalmology, Taipei Medical University, Shuang Ho Hospital, New Taipei City, Taiwan.
authors.forename: Chi-Hsin
authors.initials: CH
authors.lastname: Hsu
authors.affiliation: Department of Ophthalmology University of California-San Francisco, San Francisco, California, United States 5Department of Ophthalmology, Costa Rica University, Clinica Oftalmologica/CCSS, San Jose, Costa Rica.
authors.forename: Marissé
authors.initials: M
authors.lastname: Masís Solano
authors.affiliation: Department of Epidemiology and Biostatistics, University of California-San Francisco, San Francisco, California, United States.
authors.forename: Travis
authors.initials: T
authors.lastname: Porco
authors.affiliation: Department of Ophthalmology University of California-San Francisco, San Francisco, California, United States.
authors.forename: Shan C
authors.initials: SC
authors.lastname: Lin
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000473:pathology*; D001699:Biometry; D002386:Cataract / Q000150:complications*; D002387:Cataract Extraction; D005260:Female; D005500:Follow-Up Studies; D005902:Glaucoma, Open-Angle / Q000150:complications / Q000503:physiopathology*; D006068:Gonioscopy; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D007908:Lens, Crystalline / Q000503:physiopathology; D007910:Lenses, Intraocular; D008297:Male; D011184:Postoperative Period; D057234:Preoperative Period; D011446:Prospective Studies; D014792:Visual Acuity