title: Strategies and Methods for the Synthesis of Anticancer Natural Product Neopeltolide and its Analogs.
abstract: Neopeltolide, isolated in 2007, with its novel structural features and potent anti cancer cell proliferation activity, has attracted a tremendous amount of synthetic efforts. This review briefly and chronologically summarizes each of the synthesis with the main focus on the strategies and methodologies for the construction of itscis-tetrahydropyran-containing macrolactone core.
authors.affiliation: Department of Chemistry and Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, IN 47907, USA.
authors.forename: Yu
authors.initials: Y
authors.lastname: Bai
authors.affiliation: Department of Chemistry and Center for Cancer Research, Purdue University, 720 Clinic Drive, West Lafayette, IN 47907, USA.
authors.forename: Mingji
authors.initials: M
authors.lastname: Dai
keywords: anticancer; carbonylation; macrolactone; neopeltolide; palladium; tetrahydropyran