title: Current Trends in PET and Combined (PET/CT and PET/MR) Systems Design.
abstract: Molecular imaging using high-resolution PET instrumentation has a pivotal role in basic and clinical research. The development of optimized detection geometries combined with high-performance detector technologies and compact designs of PET tomographs has become the goal of active research groups in academic and corporate settings. More recently, the introduction of dual-modality PET/CT imaging systems in clinical environments has revolutionized the practice of diagnostic imaging. This article discusses recent advances in PET instrumentation and the advantages and challenges of multimodality imaging systems including PET/MR. Future opportunities and the challenges facing the adoption of multimodality imaging instrumentation and its role in biomedical research are also addressed.
authors.affiliation: Department of Radiology and Medical Informatics, Division of Nuclear Medicine, Geneva University Hospital, CH-1211 Geneva, Switzerland. Electronic address: habib.zaidi@hcuge.ch.
authors.forename: Habib
authors.initials: H
authors.lastname: Zaidi
authors.affiliation: Department of Radiology, Division of Nuclear Medicine, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
authors.forename: Abass
authors.initials: A
authors.lastname: Alavi