title: Combined pulsed dye and CO2 lasers in the treatment of angiolymphoid hyperplasia with eosinophilia.
abstract: Angiolymphoid hyperplasia with eosinophilia (ALHE) is an uncommon dermatosis of unknown etiology that manifests as characteristic red nodules and papules with a predilection for the scalp and periauricular region. Treatment is required for both esthetic and functional reasons, as lesions may ulcerate and bleed. Many treatment approaches have been reported, including excision, systemic medical approaches, topical or intralesional therapies, and non-invasive modalities including cryotherapy, electrosurgery, and laser. Treatments have exhibited variable efficacy, and the recurrence rate is 100 %. We report the combination of pulsed dye laser and CO2 laser in the treatment of ALHE in 14 patients. All patients exhibited clinical response after a mean of 2.4 ± 0.4 treatment sessions. The clinical efficacy of the combined treatment, together with its well-tolerated nature, render the use of pulsed dye laser in combination with CO2 laser, a viable treatment for debulking ALHE lesions. Ongoing maintenance treatments are needed to due to the high degree of relapse.
authors.affiliation: Department of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
authors.forename: Lior
authors.initials: L
authors.lastname: Sagi
authors.affiliation: Herzelia Dermatology and Laser Center, Herzelia Pituach, Israel.
authors.forename: Shlomit
authors.initials: S
authors.lastname: Halachmi
authors.affiliation: Laser Unit, Department of Dermatology, Rabin Medical Center, Petach Tikva, Israel. docalevi@gmail.com.
authors.forename: Assi
authors.initials: A
authors.lastname: Levi
authors.affiliation: Department of Dermatology, Schneider Children's Medical Center, Petach Tikva, Israel.|Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Dan Ben
authors.initials: DB
authors.lastname: Amitai
authors.affiliation: Department of Dermatology, Hadassah Medical Organization-The Hebrew University Medical School, Jerusalem, Israel.
authors.forename: Claes D
authors.initials: CD
authors.lastname: Enk
authors.affiliation: Laser Unit, Department of Dermatology, Rabin Medical Center, Petach Tikva, Israel.|Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors.forename: Moshe
authors.initials: M
authors.lastname: Lapidoth
mesh_terms: D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000473:pathology / Q000534:rehabilitation*; D003131:Combined Modality Therapy; D017679:Cryotherapy; D005260:Female; D006801:Humans; D054025:Lasers, Dye / Q000627:therapeutic use*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local
keywords: Angiolymphoid hyperplasia; Carbon dioxide; Laser; Selective photothermolysis