title: Prevalence of type 2 diabetes mellitus among inland residents in China (2000-2014): A meta-analysis.
abstract: OBJECTIVE
  Besides the aging population in China, the following have become serious public health problems: increasing urban population, lifestyle changes and diabetes. We assessed the epidemiology of type 2 diabetes mellitus in China between 2000 and 2014, and analyzed time trends to better determine the prevalence status of diabetes in China and to provide a basis for prevention and decision-making.
  
  
  METHODS
  In our systematic review, we searched China National Knowledge Infrastructure, Chinese VIP Information, Wanfang and PubMed databases for studies on type 2 diabetes mellitus between 2000 and 2014 in China. Two investigators extracted the data and assessed the quality of the included literature independently. We excluded studies that did not use 1999 World Health Organization criteria for diabetes. We also excluded reviews and viewpoints, studies with insufficient data, studies that were not carried out in mainland China and studies on troops, community, schools or physical examination people. We used stata 12.0 to combine the prevalence of all studies, calculated the pooled prevalence and its 95% confidence interval, and analyzed the differences among men/women, urban/rural areas and year of study. We calculated the prevalence of seven geographic areas of China, respectively, and mapped the distribution in the whole country to estimate the pooled prevalence of each area.
  
  
  RESULTS
  Our search returned 4,572 studies, 77 of which satisfied the inclusion criteria. The included studies had a total of 1,287,251 participants, in which 680,574 cases of type 2 diabetes mellitus were recorded. The overall prevalence (9.1%) has been increasing since the 1970s, and it increased rapidly with age. The prevalence of the 65-74 years group was as high as 14.1%. Meanwhile, the prevalence among men/women and urban/rural areas was significantly different. The prevalence was 9.9% for men and 11.6% for women, which were significantly higher than the average at the end of the last century and the beginning of this century. The prevalence rate in urban areas (11.4%) was significantly higher than that in rural areas and in urban-rural fringe areas, and the prevalence in rural areas (8.2%) was slightly higher than that in urban-rural fringe areas (7.5%). In addition, the prevalence in each geographic area were estimated and mapped, which showed a large imbalance in the map.
  
  
  CONCLUSIONS
  Our analysis suggested that type 2 diabetes mellitus is highly prevalent in China. These results underscore the urgent need for the government to vigorously strengthen the management of diabetes prevention and control.
authors.affiliation: School of Medicine, Nantong University, Nantong, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Yang
authors.affiliation: School of Basic Medical Sciences, Nanjing University of Chinese Medicine, Nanjing, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Shao
authors.affiliation: School of Nursing, Nanjing University of Chinese Medicine, Nanjing, China.
authors.forename: Yaoyao
authors.initials: Y
authors.lastname: Bian
authors.affiliation: School of Medicine, Nantong University, Nantong, China.
authors.forename: Huiqun
authors.initials: H
authors.lastname: Wu
authors.affiliation: School of Medicine, Nantong University, Nantong, China.
authors.forename: Lili
authors.initials: L
authors.lastname: Shi
authors.affiliation: Jingwen Library, Nanjing University of Chinese Medicine, Nanjing, China.
authors.forename: Li
authors.initials: L
authors.lastname: Zeng
authors.affiliation: Jingwen Library, Nanjing University of Chinese Medicine, Nanjing, China.
authors.forename: Wenlin
authors.initials: W
authors.lastname: Li
authors.affiliation: School of Medicine, Nantong University, Nantong, China. dongjc@ntu.edu.cn.
authors.forename: Jiancheng
authors.initials: J
authors.lastname: Dong
mesh_terms: D000328:Adult; D000368:Aged; D002681:China / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000517:prevention & control; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012424:Rural Population; D014505:Urban Population; D055815:Young Adult
keywords: China; Prevalence; Type 2 diabetes mellitus