title: Multi-Target Stool DNA Test: Is the Future Here?
abstract: Colorectal cancer (CRC) screening reduces CRC incidence and mortality and is widely recommended. However, despite these demonstrated benefits, a large percentage of the population remains unscreened. The multi-target stool DNA (MT-sDNA) test is a new, non-invasive option for CRC screening that has a high accuracy rate in detection of colorectal neoplasia and offers great opportunity to enhance screening uptake. This review provides the current state of the art knowledge about the use of MT-sDNA in CRC screening.
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA. sweetser.seth@mayo.edu.
authors.forename: Seth
authors.initials: S
authors.lastname: Sweetser
authors.affiliation: Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN, 55905, USA.
authors.forename: David A
authors.initials: DA
authors.lastname: Ahlquist
mesh_terms: D015179:Colorectal Neoplasms / Q000175:diagnosis* / Q000235:genetics; D004273:DNA, Neoplasm / Q000032:analysis*; D055088:Early Detection of Cancer / Q000379:methods*; D005243:Feces / Q000737:chemistry*; D006801:Humans; D008403:Mass Screening / Q000379:methods; D011230:Precancerous Conditions / Q000175:diagnosis / Q000235:genetics; D012680:Sensitivity and Specificity
chemical_list: D004273:DNA, Neoplasm
keywords: Colorectal cancer; Screening; Stool DNA