title: Antibacterial properties of modified biodegradable PHB non-woven fabric.
abstract: The antibacterial properties of poly(hydroxybutyrate) (PHB) non-woven fabric were explored in this study. The PHB was activated by plasma modification and subsequently processed with either immersion into a solution of nanoparticles or direct metallization. The wettability and surface chemistry of the PHB surface was determined. The thickness of the sputtered nanolayer on PHB fabric was characterized. It was found that plasma modification led to a formation of strongly hydrophilic surface, while the subsequent metallization by silver or gold resulted in a significantly increased water contact angle. Further, it was found that antibacterial activity may be controlled by the type of a metal and deposition method used. The immersion of plasma modified fabric into Ag nanoparticle solution led to enhanced antibacterial efficiency of PHB against Escherichia coli (E. coli). Direct silver sputtering on PHB fabric was proved to be a simple method for construction of a surface with strong antibacterial potency against both Escherichia coli (E. coli) and Staphylococcus epidermidis (S. epidermidis). We demonstrated the antibacterial activity of PHB fabric modified by plasma activation and consecutive selection of a treatment method for an effective antibacterial surface construction.
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology, Prague, Czech Republic. Electronic address: petr.slepicka@vscht.cz.
authors.forename: P
authors.initials: P
authors.lastname: Slepička
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology, Prague, Czech Republic.
authors.forename: Z
authors.initials: Z
authors.lastname: Malá
authors.affiliation: Department of Biochemistry and Microbiology, University of Chemistry and Technology, Prague, Czech Republic.
authors.forename: S
authors.initials: S
authors.lastname: Rimpelová
authors.affiliation: Department of Solid State Engineering, University of Chemistry and Technology, Prague, Czech Republic.
authors.forename: V
authors.initials: V
authors.lastname: Švorčík
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry* / Q000494:pharmacology; D004926:Escherichia coli / Q000187:drug effects; D008826:Microbial Sensitivity Tests; D053758:Nanoparticles / Q000737:chemistry; D011091:Polyesters / Q000737:chemistry* / Q000494:pharmacology; D012834:Silver / Q000737:chemistry; D013212:Staphylococcus epidermidis / Q000187:drug effects; D013499:Surface Properties; D017155:Wettability
chemical_list: D000900:Anti-Bacterial Agents; D011091:Polyesters; D012834:Silver
keywords: Antibacterial properties; Biopolymers; Characterization; Metal nanostructure; Plasma modification