title: The Risks to Patient Privacy from Publishing Data from Clinical Anesthesia Studies.
abstract: In this article, we consider the privacy implications of posting data from small, randomized trials, observational studies, or case series in anesthesia from a few (e.g., 1-3) hospitals. Prior to publishing such data as supplemental digital content, the authors remove attributes that could be used to re-identify individuals, a process known as "anonymization." Posting health information that has been properly "de-identified" is assumed to pose no risks to patient privacy. Yet, computer scientists have demonstrated that this assumption is flawed. We consider various realistic scenarios of how the publication of such data could lead to breaches of patient privacy. Several examples of successful privacy attacks are reviewed, as well as the methods used. We survey the latest models and methods from computer science for protecting health information and their application to posting data from small anesthesia studies. To illustrate the vulnerability of such published data, we calculate the "population uniqueness" for patients undergoing one or more surgical procedures using data from the State of Texas. For a patient selected uniformly at random, the probability that an adversary could match this patient's record to a unique record in the state external database was 42.8% (SE < 0.1%). Despite the 42.8% being an unacceptably high level of risk, it underestimates the risk for patients from smaller states or provinces. We propose an editorial policy that greatly reduces the likelihood of a privacy breach, while supporting the goal of transparency of the research process.
authors.affiliation: From the *Department of Health Management and Policy, School of Public Health, University of North Texas-Health Science Center, Fort Worth, Texas; †Division of Management Consulting, Department of Anesthesia, University of Iowa, Iowa City, Iowa; and ‡Department of Computer Science, George Washington University, Washington, DC.
authors.forename: Liam
authors.initials: L
authors.lastname: O'Neill
authors.forename: Franklin
authors.initials: F
authors.lastname: Dexter
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
mesh_terms: D016494:Computer Security; D003219:Confidentiality / Q000331:legislation & jurisprudence; D000068240:Data Anonymization; D057225:Data Mining; D016208:Databases, Factual; D035081:Editorial Policies; D028744:Ethics Committees, Research; D020408:Health Insurance Portability and Accountability Act; D006801:Humans; D033181:Information Dissemination / Q000331:legislation & jurisprudence; D007297:Inpatients; D064887:Observational Studies as Topic / Q000331:legislation & jurisprudence / Q000379:methods*; D010506:Periodicals as Topic / Q000331:legislation & jurisprudence; D000068241:Personally Identifiable Information; D016032:Randomized Controlled Trials as Topic / Q000331:legislation & jurisprudence / Q000379:methods*; D012107:Research Design / Q000331:legislation & jurisprudence; D013781:Texas; D014481:United States