title: Unsuspected Ganglioneuroma of the Choroid Diagnosed after Enucleation.
abstract: We report a case of an unsuspected ganglioneuroma of the choroid in a patient with neurofibromatosis type 1. A 5-year-old girl presented from an outside institution with right proptosis and glaucoma since birth. Magnetic resonance imaging was obtained and showed a cavernous sinus mass extending into the right orbit and multiple orbital lesions. Additionally, increased signal in the posterior globe of the right eye was noted, but its etiology was unclear at the time. She was lost to follow-up for 3 years and later returned with a blind painful eye. Enucleation was performed, and histopathology was significant for diffuse choroidal ganglioneuroma and advanced glaucoma. We report the atypical history, examination findings, and histopathology to support the diagnosis.
authors.affiliation: Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Ill., USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Mbagwu
authors.affiliation: Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Ill., USA.
authors.forename: Bahram
authors.initials: B
authors.lastname: Rahmani
authors.affiliation: Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, Ill., USA.
authors.forename: Arth
authors.initials: A
authors.lastname: Srivastava
authors.affiliation: Department of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Ill., USA.
authors.forename: Delilah
authors.initials: D
authors.lastname: Burrowes
authors.affiliation: Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, Ill., USA.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Bryar
keywords: Ganglioneuroma; Neurofibromatosis type 1; Orbital imaging; Orbital tumor; von Recklinghausen disease