title: Prevalence of Insomnia and Associated Factors in Outpatients With Generalized Anxiety Disorder Treated in Psychiatric Clinics.
abstract: Sleep disturbance is one of the key diagnostic criteria for generalized anxiety disorder (GAD). In this cross-sectional, prospective, observational, and multicenter study, factors associated with the prevalence of insomnia and the impact of insomnia-associated factors on quality of life were evaluated. Using multivariate analyses, the factor most strongly associated with the presence of insomnia (ISI ≥ 8) was the severity of the disorder (Odds Ratio [OR]: 9.253 for severe GAD; 95% Confidence Interval [CI]: 1.914-44.730; p = 0.006), pain interference and symptoms of depression (OR: 1.018; 95% CI 1.003-1.033; p = 0.016 and OR: 1.059; 95% CI 1.019-1.101; p = 0.004, respectively). Insomnia was not related to quality of life. Our results show insomnia to be a common health condition among patients with GAD, associated with the severity of anxiety and depressive symptoms and pain interference.
authors.affiliation: a Servicio Psiquiatría B ., Hospital General Universitario Gregorio Marañón , Madrid , Spain.
authors.forename: F
authors.initials: F
authors.lastname: Ferre Navarrete
authors.affiliation: b Medical Unit, Pfizer GEP, S. L. U ., Madrid , Spain.
authors.forename: M
authors.initials: M
authors.lastname: Pérez Páramo
authors.affiliation: c Servicio de Neurofisiología , Hospital Arnau de Vilanova , Madrid , Spain.
authors.forename: J
authors.initials: J
authors.lastname: Fermin Ordoño
authors.affiliation: b Medical Unit, Pfizer GEP, S. L. U ., Madrid , Spain.
authors.forename: V
authors.initials: V
authors.lastname: López Gómez
mesh_terms: D000328:Adult; D001007:Anxiety / Q000453:epidemiology; D001008:Anxiety Disorders / Q000453:epidemiology*; D003155:Community Mental Health Centers; D003430:Cross-Sectional Studies; D003863:Depression / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016017:Odds Ratio; D010045:Outpatients / Q000523:psychology* / Q000706:statistics & numerical data*; D010146:Pain / Q000453:epidemiology / Q000523:psychology; D015995:Prevalence; D011446:Prospective Studies; D011788:Quality of Life; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology* / Q000523:psychology*