title: Cardiovascular surveillance in breast cancer treatment: A more individualized approach is needed.
abstract: Newly developed treatment strategies for breast cancer have reduced mortality rates over the past decades. Patients with breast cancer represent a heterogeneous population. Differences in the severity of the disease require diverse treatment options. Women have distinct individual risk patterns for cardiovascular disease that may affect their susceptibility to cardiotoxicity during therapy. While breast cancer treatment is targeted more on tumor and patient characteristics, a tailored individual approach with early and late cardiosurveillance is not yet implemented in routine care. Newly available cardiac imaging techniques are better suited to the early detection of cardiotoxicity and should be used more often in those patients at highest risk, as the early intervention afforded will improve their quality of life and prognosis.
authors.affiliation: Department of Cardiology, Women's Cardiac Health Radboud University Medical Center, Geert Grooteplein-Zuid 10, Nijmegen, GA 9525, The Netherlands. Electronic address: angela.maas@radboudumc.nl.
authors.forename: Angela H E M
authors.initials: AH
authors.lastname: Maas
authors.affiliation: Department of Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Nelleke
authors.initials: N
authors.lastname: Ottevanger
authors.affiliation: Scientific Institute for Quality of Healthcare, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Femke
authors.initials: F
authors.lastname: Atsma
authors.affiliation: Department of Cardiology, University Medical Center Utrecht, The Netherlands.
authors.forename: Maarten J
authors.initials: MJ
authors.lastname: Cramer
authors.affiliation: Department of Radiology, University Medical Center Utrecht, The Netherlands.
authors.forename: Tim
authors.initials: T
authors.lastname: Leiner
authors.affiliation: Department of Radiation Oncology, Radboud University Medical Center, Nijmegen, The Netherlands.
authors.forename: Philip
authors.initials: P
authors.lastname: Poortmans
mesh_terms: D000970:Antineoplastic Agents / Q000009:adverse effects / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000532:radiotherapy; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging* / Q000209:etiology; D005260:Female; D006801:Humans; D057285:Precision Medicine
chemical_list: D000970:Antineoplastic Agents
keywords: Breast cancer; Cardiosurveillance; Cardiotoxicity; Cardiovascular toxicity