title: JUB1 suppresses Pseudomonas syringae-induced defense responses through accumulation of DELLA proteins.
abstract: Phytohormones act in concert to coordinate plant growth and the response to environmental cues. Gibberellins (GAs) are growth-promoting hormones that recently emerged as modulators of plant immune signaling. By regulating the stability of DELLA proteins, GAs intersect with the signaling pathways of the classical primary defense hormones, salicylic acid (SA) and jasmonic acid (JA), thereby altering the final outcome of the immune response. DELLA proteins confer resistance to necrotrophic pathogens by potentiating JA signaling and raise the susceptibility to biotrophic pathogens by attenuating the SA pathway. Here, we show that JUB1, a core element of the GA - brassinosteroid (BR) - DELLA regulatory module, functions as a negative regulator of defense responses against Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) and mediates the crosstalk between growth and immunity.
authors.affiliation: a University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße , Potsdam-Golm , Germany.|b Max-Planck Institute of Molecular Plant Physiology, Am Mühlenberg , Potsdam-Golm , Germany.
authors.forename: Sara
authors.initials: S
authors.lastname: Shahnejat-Bushehri
authors.affiliation: a University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße , Potsdam-Golm , Germany.|b Max-Planck Institute of Molecular Plant Physiology, Am Mühlenberg , Potsdam-Golm , Germany.
authors.forename: Barbara
authors.initials: B
authors.lastname: Nobmann
authors.affiliation: a University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße , Potsdam-Golm , Germany.|b Max-Planck Institute of Molecular Plant Physiology, Am Mühlenberg , Potsdam-Golm , Germany.
authors.forename: Annapurna
authors.initials: A
authors.lastname: Devi Allu
authors.affiliation: a University of Potsdam, Institute of Biochemistry and Biology, Karl-Liebknecht-Straße , Potsdam-Golm , Germany.|b Max-Planck Institute of Molecular Plant Physiology, Am Mühlenberg , Potsdam-Golm , Germany.
authors.forename: Salma
authors.initials: S
authors.lastname: Balazadeh
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000276:immunology* / Q000378:metabolism / Q000382:microbiology*; D029681:Arabidopsis Proteins / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D008954:Models, Biological; D057865:Plant Immunity / Q000235:genetics; D030821:Plants, Genetically Modified; D044224:Pseudomonas syringae / Q000502:physiology*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000378:metabolism*
chemical_list: C588250:ANAC042 protein, Arabidopsis; D029681:Arabidopsis Proteins; C109555:GAI protein, Arabidopsis; D012333:RNA, Messenger; D014157:Transcription Factors
keywords: Arabidopsis; DELLA proteins; defense; gibberellin; jasmonic acid; pathogens; salicylic acid; transcription factor