title: (18)F NaF PET/CT Versus Conventional Bone Scanning in the Assessment of Benign Bone Disease.
abstract: Nuclear physicians in many centers nowadays have the choice of using different nuclear bone-imaging modalities. (18)F-labeled sodium fluoride (NaF) PET with computed tomography (PET/CT) is a promising tool for the evaluation of benign bone disease. The indications for NaF PET/CT in clinical practice are probably the same as those established for (99m)Tc-labeled methylene diphosphonate bone scintigraphy and single-photon emission computed tomography (SPECT)/CT. At present only preliminary data, often with a limited number of patients and lacking comparison with (99m)Tc-MDP SPECT/CT, are available. This article reviews the available literature and summarizes the authors' experience with NaF PET/CT in benign bone disease.
authors.affiliation: Department of Radiology and Nuclear Medicine, Cantonal Hospital Lucerne, Spitalstrasse, 6000 Lucerne 16, Switzerland.
authors.forename: Klaus
authors.initials: K
authors.lastname: Strobel
authors.affiliation: Department of Radiology and Nuclear Medicine, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
authors.forename: Reza
authors.initials: R
authors.lastname: Vali