title: IDH1 mutation can be present in diffuse astrocytomas and giant cell glioblastomas of young children under 10 years of age.
authors.affiliation: Division of Neuropathology, Department of Pathology, University of California, 513 Parnassus Ave, Health Sciences West 451, Box 0102, San Francisco, CA, 94143, USA.
authors.forename: Sean P
authors.initials: SP
authors.lastname: Ferris
authors.affiliation: Division of Neuropathology, Department of Pathology, University of California, 513 Parnassus Ave, Health Sciences West 451, Box 0102, San Francisco, CA, 94143, USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Goode
authors.affiliation: Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, 94143, USA.
authors.forename: Nancy M
authors.initials: NM
authors.lastname: Joseph
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, 94143, USA.
authors.forename: Cassie N
authors.initials: CN
authors.lastname: Kline
authors.affiliation: Division of Hematology/Oncology, Valley Children's Hospital, Madera, CA, 93636, USA.
authors.forename: David
authors.initials: D
authors.lastname: Samuel
authors.affiliation: Department of Neurological Surgery, University of California, San Francisco, CA, 94143, USA.
authors.forename: Nalin
authors.initials: N
authors.lastname: Gupta
authors.affiliation: Division of Neuropathology, Department of Pathology, University of California, 513 Parnassus Ave, Health Sciences West 451, Box 0102, San Francisco, CA, 94143, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Bollen
authors.affiliation: Division of Neuropathology, Department of Pathology, University of California, 513 Parnassus Ave, Health Sciences West 451, Box 0102, San Francisco, CA, 94143, USA.|Department of Neurological Surgery, University of California, San Francisco, CA, 94143, USA.
authors.forename: Arie
authors.initials: A
authors.lastname: Perry
authors.affiliation: Division of Pediatric Hematology/Oncology, Department of Pediatrics, University of California, San Francisco, CA, 94143, USA.|Department of Neurological Surgery, University of California, San Francisco, CA, 94143, USA.|Department of Neurology, University of California, San Francisco, CA, 94143, USA.
authors.forename: Sabine
authors.initials: S
authors.lastname: Mueller
authors.affiliation: Division of Neuropathology, Department of Pathology, University of California, 513 Parnassus Ave, Health Sciences West 451, Box 0102, San Francisco, CA, 94143, USA. david.solomon@ucsf.edu.|Clinical Cancer Genomics Laboratory, University of California, San Francisco, CA, 94143, USA. david.solomon@ucsf.edu.
authors.forename: David A
authors.initials: DA
authors.lastname: Solomon
mesh_terms: D001254:Astrocytoma / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D014408:Biomarkers, Tumor / Q000235:genetics; D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D002648:Child; D017809:Fatal Outcome; D005260:Female; D005909:Glioblastoma / Q000000981:diagnostic imaging / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D006801:Humans; D007521:Isocitrate Dehydrogenase / Q000235:genetics*; D008297:Male; D009154:Mutation
chemical_list: D014408:Biomarkers, Tumor; D007521:Isocitrate Dehydrogenase; C543588:IDH1 protein, human