title: Effect of heart rate on the diagnostic accuracy of 256-slice computed tomography angiography in the detection of coronary artery stenosis: ROC curve analysis.
abstract: The aim of the present study was to investigate the effect of heart rate (HR) on the diagnostic accuracy of 256-slice computed tomography angiography (CTA) in the detection of coronary artery stenosis. Coronary imaging was performed using a Philips 256-slice spiral CT, and receiver operating characteristic (ROC) curve analysis was conducted to evaluate the diagnostic value of 256-slice CTA in coronary artery stenosis. The HR of the research subjects in the study was within a certain range (39-107 bpm). One hundred patients suspected of coronary heart disease underwent 256-slice CTA examination. The cases were divided into three groups: Low HR (HR <75 bpm), moderate HR (75≤ HR <90 bpm) and high HR (HR ≥90 bpm). For the three groups, two observers independently assessed the image quality for all coronary segments on a four-point ordinal scale. An image quality of grades 1-3 was considered diagnostic, while grade 4 was non-diagnostic. A total of 97.76% of the images were diagnostic in the low-HR group, 96.86% in the moderate-HR group and 95.80% in the high-HR group. According to the ROC curve analysis, the specificity of CTA in diagnosing coronary artery stenosis was 98.40, 96.00 and 97.60% in the low-, moderate- and high-HR groups, respectively. In conclusion, 256-slice coronary CTA can be used to clearly show the main segments of the coronary artery and to effectively diagnose coronary artery stenosis. Within the range of HRs investigated, HR was found to have no significant effect on the diagnostic accuracy of 256-slice coronary CTA for coronary artery stenosis.
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Gang
authors.initials: G
authors.lastname: Wang
authors.affiliation: Department of Oncology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Yifen
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Zhentao
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Yulan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Manqiu
authors.initials: M
authors.lastname: Liang
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Huanchu
authors.initials: H
authors.lastname: Yuan
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Haiping
authors.initials: H
authors.lastname: Shen
authors.affiliation: Department of Radiology, People's Hospital of Dongguan, Dongguan, Guangdong 523000, P.R. China.
authors.forename: Dewei
authors.initials: D
authors.lastname: Li
keywords: coronary angiography; coronary stenosis disease; receiver operating characteristic curve; tomography