title: Morphometric MRI changes in intracranial hypertension due to cerebral venous thrombosis: a retrospective imaging study.
abstract: OBJECTIVE
  To evaluate whether some magnetic resonance imaging (MRI) signs suggesting idiopathic intracranial hypertension (IIH) could also be found in intracranial hypertension (IH) due to cerebral venous thrombosis (CVT) and to assess their possible contribution to diagnosing this disorder.
  
  
  METHODS
  Thirty-one patients with IH due to CVT were evaluated prospectively using MRI. A group of 33 age- and sex-matched healthy volunteers served as controls. The optic nerve and sheath, pituitary gland, and ventricles were assessed. The prevalence of each imaging feature was compared between the two groups.
  
  
  RESULTS
  Optic nerve sheath (ONS) dilatation and decreased pituitary gland height were the most valid signs suggesting IH in CVT patients: sensitivity 70.97% and 87.1%, respectively; specificity 96.97% and 72.73%, respectively; area under the curve 0.840 and 0.809, respectively. The MRI finding that showed the strongest association with IH in CVT patients was ONS dilatation (odds ratio 78.5).
  
  
  CONCLUSIONS
  The combination of T1-weighted volumetric MRI and magnetic resonance venography could be helpful for diagnosing IH with CVT. Abnormalities of the ONS and the pituitary gland were reliable diagnostic signs for IH due to CVT.
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Dong
authors.affiliation: Department of Health Examination Center, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: Ying-Mei
authors.initials: YM
authors.lastname: Zheng
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: Xiao-Li
authors.initials: XL
authors.lastname: Li
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: He-Xiang
authors.initials: HX
authors.lastname: Wang
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: Da-Peng
authors.initials: DP
authors.lastname: Hao
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: Pei
authors.initials: P
authors.lastname: Nie
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Pang
authors.affiliation: Department of Radiology, The Affiliated Hospital of Qingdao University, NO.16, Jiangsu Road, Qingdao 266000, China. Electronic address: xuwenjianqd@sina.com.
authors.forename: Wen-Jian
authors.initials: WJ
authors.lastname: Xu
mesh_terms: D000328:Adult; D002550:Cerebral Veins / Q000000981:diagnostic imaging / Q000473:pathology*; D005260:Female; D006801:Humans; D019586:Intracranial Hypertension / Q000150:complications* / Q000473:pathology*; D018810:Magnetic Resonance Angiography / Q000379:methods*; D008297:Male; D015588:Observer Variation; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D012851:Sinus Thrombosis, Intracranial / Q000150:complications* / Q000000981:diagnostic imaging / Q000473:pathology*