title: A Base-Catalyzed, Domino Aldol/hetero-Diels-Alder Synthesis of Tricyclic Pyrano[3,4-c]chromenes in Glycerol.
abstract: The domino aldol/hetero-Diels-Alder synthesis of some new tricyclic pyrano[3,4-c]chromene derivatives has been achieved successfully after assembling a variety of acyclic or cyclic monoketones with prenyl ether-tethered aldehydes in the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene in glycerol at 120 °C. The hitherto unreported stereochemical outcome of this synthetic sequence was studied and established on the basis of single-crystal X-ray diffraction data and 2D NMR NOESY spectroscopy along with the isolation and characterization of the intermediate Aldol condensation product.
authors.affiliation: Department of Chemistry, Sardar Patel University , Vallabh Vidyanagar, Anand District, Gujarat 388120, India.
authors.forename: Bhagyashri D
authors.initials: BD
authors.lastname: Parmar
authors.affiliation: Department of Chemistry, Sardar Patel University , Vallabh Vidyanagar, Anand District, Gujarat 388120, India.
authors.forename: Tushar R
authors.initials: TR
authors.lastname: Sutariya
authors.affiliation: Department of Chemistry, Sardar Patel University , Vallabh Vidyanagar, Anand District, Gujarat 388120, India.
authors.forename: Gaurangkumar C
authors.initials: GC
authors.lastname: Brahmbhatt
authors.affiliation: Department of Chemistry, Sardar Patel University , Vallabh Vidyanagar, Anand District, Gujarat 388120, India.
authors.forename: Narsidas J
authors.initials: NJ
authors.lastname: Parmar
authors.affiliation: Post-Graduate Department of Physics, University of Jammu , Jammu Tawi 180006, India.
authors.forename: Rajni
authors.initials: R
authors.lastname: Kant
authors.affiliation: Post-Graduate Department of Physics, University of Jammu , Jammu Tawi 180006, India.
authors.forename: Vivek K
authors.initials: VK
authors.lastname: Gupta