title: Gastrointestinal bleeding in a patient with a continuous-flow biventricular assist device.
abstract: The association between continuous-flow left ventricular assist devices (CF-LVADs) and gastrointestinal (GI) bleeding from angiodysplasia is well recognized. However, the association between continuous-flow biventricular assist devices (CF-BIVADs) and bleeding angiodysplasia is less understood. We report a case of GI bleeding from a patient with a CF-BIVAD. The location of GI bleeding was identified by nuclear red blood cell bleeding scan. The vascular malformation leading to the bleed was identified and localized on angiography and then by pathology. The intensity of bleeding, reflected by number of units of packed red blood cells needed for normalization of hemoglobin, as well as the time to onset of bleeding after transplantation, are similar to that seen in the literature for CF-LVADs and pulsatile BIVADs. While angiography only detected a dilated late draining vein, pathology demonstrated the presence of both arterial and venous dilation in the submucosa, vascular abnormalities characteristic of a late arteriovenous malformation.
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: Raymond V
authors.initials: RV
authors.lastname: Mirasol
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: Jason J
authors.initials: JJ
authors.lastname: Tholany
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: Hasini
authors.initials: H
authors.lastname: Reddy
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: Billie S
authors.initials: BS
authors.lastname: Fyfe-Kirschner
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: Christina L
authors.initials: CL
authors.lastname: Cheng
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: Issam F
authors.initials: IF
authors.lastname: Moubarak
authors.affiliation: Raymond V Mirasol, Department of Internal Medicine, Jersey Shore University Medical Center, Neptune, NJ 07753, United Sates.
authors.forename: John L
authors.initials: JL
authors.lastname: Nosher
keywords: Angiodysplasia; Angiography; Continuous-flow ventricular assist devices; Gastrointestinal bleeding; Heart failure