title: The SnRK1 Energy Sensor in Plant Biotic Interactions.
abstract: Our understanding of plant biotic interactions has grown significantly in recent years with the identification of the mechanisms involved in innate immunity, hormone signaling, and secondary metabolism. The impact of such interactions on primary metabolism and the role of metabolic signals in the response of the plants, however, remain far less explored. The SnRK1 (SNF1-related kinase 1) kinases act as metabolic sensors, integrating very diverse stress conditions, and are key in maintaining energy homeostasis for growth and survival. Consistently, an important role is emerging for these kinases as regulators of biotic stress responses triggered by viral, bacterial, fungal, and oomycete infections as well as by herbivory. While this identifies SnRK1 as a promising target for directed modification or selection for more quantitative and sustainable resistance, its central function also increases the chances of unwanted side effects on growth and fitness, stressing the need for identification and in-depth characterization of the mechanisms and target processes involved. VIDEO ABSTRACT.
authors.affiliation: Laboratory of Molecular Plant Biology, Biology Department, University of Leuven-KU Leuven, Kasteelpark Arenberg 31, 3001 Heverlee-Leuven, Belgium.
authors.forename: Sander
authors.initials: S
authors.lastname: Hulsmans
authors.affiliation: Instituto de Fisiología y Recursos Genéticos Vegetales (IFRGV), Centro de Investigaciones Agropecuarias (CIAP), Instituto Nacional de Tecnología Agropecuaria (INTA), Camino 60 cuadras km 5.5 X5020ICA, Córdoba, Argentina.
authors.forename: Marianela
authors.initials: M
authors.lastname: Rodriguez
authors.affiliation: Centre of Microbial and Plant Genetics, Microbial and Molecular Systems Department, University of Leuven-KU Leuven, Kasteelpark Arenberg 20, 3001 Heverlee-Leuven, Belgium; Vlaams Instituut voor Biotechnologie (VIB), Department of Plant Systems Biology, Technologiepark 927, 9052 Gent, Belgium.
authors.forename: Barbara
authors.initials: B
authors.lastname: De Coninck
authors.affiliation: Laboratory of Molecular Plant Biology, Biology Department, University of Leuven-KU Leuven, Kasteelpark Arenberg 31, 3001 Heverlee-Leuven, Belgium. Electronic address: filip.rolland@bio.kuleuven.be.
authors.forename: Filip
authors.initials: F
authors.lastname: Rolland
mesh_terms: D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D010766:Phosphorylation / Q000235:genetics / Q000502:physiology; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D010944:Plants / Q000378:metabolism* / Q000382:microbiology; D017346:Protein Serine-Threonine Kinases / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology
chemical_list: D010940:Plant Proteins; C071570:SNF1-related protein kinases; D017346:Protein Serine-Threonine Kinases
keywords: SnRK1; biotic stress; metabolism; quantitative resistance