title: Pilot evaluation of ivacaftor for chronic bronchitis.
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: George M
authors.initials: GM
authors.lastname: Solomon
authors.affiliation: Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: Heather
authors.initials: H
authors.lastname: Hathorne
authors.affiliation: Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: S Vamsee
authors.initials: SV
authors.lastname: Raju
authors.affiliation: Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: Ginger
authors.initials: G
authors.lastname: Reeves
authors.affiliation: Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Department of Pharmacology and Toxicology, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: Edward P
authors.initials: EP
authors.lastname: Acosta
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; UAB Lung Health Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA.
authors.forename: Mark T
authors.initials: MT
authors.lastname: Dransfield
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Department of Pediatrics, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Cell Developmental and Integrative Biology, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294-0006, USA. Electronic address: smrowe@uab.edu.
authors.forename: Steven M
authors.initials: SM
authors.lastname: Rowe
mesh_terms: D000368:Aged; D000627:Aminophenols / Q000627:therapeutic use*; D029481:Bronchitis, Chronic / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D065101:Chloride Channel Agonists / Q000008:administration & dosage*; D019005:Cystic Fibrosis Transmembrane Conductance Regulator / Q000187:drug effects*; D004311:Double-Blind Method; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D058990:Molecular Targeted Therapy; D010865:Pilot Projects; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy* / Q000235:genetics; D015363:Quinolones / Q000627:therapeutic use*; D018570:Risk Assessment; D016896:Treatment Outcome
chemical_list: D000627:Aminophenols; D065101:Chloride Channel Agonists; D015363:Quinolones; D019005:Cystic Fibrosis Transmembrane Conductance Regulator; C545203:ivacaftor