title: Human Platelet Lipidomics: Variance, Visualization, Flux, and Fuel.
abstract: The cardioprotection afforded by low-dose aspirin reflects the biological importance of the platelet lipid thromboxane A2. In this issue of Cell Metabolism, Slatter et al. (2016) illuminate the breadth, complexity, and variability of the human platelet lipidome under conditions of thrombin activation and aspirin suppression, potentially facilitating the pursuit of precision medicine.
authors.affiliation: Institute for Translational Medicine and Therapeutics, 10-123 Smilow Center for Translational Research, Building 421, 3400 Civic Center Boulevard, Philadelphia, PA 19104-5158, USA. Electronic address: garret@upenn.edu.
authors.forename: Garret A
authors.initials: GA
authors.lastname: FitzGerald
mesh_terms: D001792:Blood Platelets / Q000378:metabolism*; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000096:biosynthesis; D008954:Models, Biological; D015539:Platelet Activation
chemical_list: D008055:Lipids