title: CHA2DS2-VASc Score Predicts In-Hospital and Long-Term Clinical Outcomes in Patients With ST-Segment Elevation Myocardial Infarction Who Were Undergoing Primary Percutaneous Coronary Intervention.
abstract: CHA2DS2-VASc score includes similar risk factors for coronary artery disease. We hypothesized that admission CHA2DS2-VASc score might be predictive of adverse clinical outcomes for patients with ST-segment elevation myocardial infarction (STEMI) who were undergoing primary percutaneous coronary intervention. A total of 647 patients with STEMI enrolled in this study. The study population was divided into 2 groups according to their admission CHA2DS2-VASc score. The low group (n = 521) was defined as CHA2DS2-VASc score ≤2, and the high group (n = 126) was defined as CHA2DS2-VASc score >2. Patients in the high group had significantly higher incidence of in-hospital cardiovascular mortality (8.7% vs 1.9%; P < .001). Long-term mortality was significantly frequent in the high group (13.4% vs 3.6%, P < .001). Hypertension, admission CHA2DS2-VASc score, and Killip class >1 were independent predictors of long-term mortality. Admission CHA2DS2-VASc score >2 was identified as an effective cutoff point for long-term mortality (area under curve = 0.821; 95% confidence interval: 0.76-0.89; P < .001). CHA2DS2-VASc score is a simple, very useful, easily remembered bedside score for predicting in-hospital and long-term adverse clinical outcomes in STEMI.
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Bozbay
authors.affiliation: 2 Department of Cardiology, School of Medicine, Bezmi Alem Vakif University, Istanbul, Turkey.
authors.forename: Huseyin
authors.initials: H
authors.lastname: Uyarel
authors.affiliation: 3 Department of Cardiology, Ankara Numune Hospital, Ankara, Turkey.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Cicek
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Oz
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Keskin
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Murat
authors.affiliation: 4 Department of Cardiology, Elazıg Research and Training Hospital, Elazıg, Turkey.
authors.forename: Ersin
authors.initials: E
authors.lastname: Yildirim
authors.affiliation: 5 Department of Cardiology, Amasya Sabuncu Serafeddin Research and Training Hospital, Amasya, Turkey.
authors.forename: Gurkan
authors.initials: G
authors.lastname: Karaca
authors.affiliation: 2 Department of Cardiology, School of Medicine, Bezmi Alem Vakif University, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Ergelen
authors.affiliation: 1 Department of Cardiology, Dr Siyami Ersek Cardiovascular and Thoracic Surgery Research and Training Hospital, Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eren
mesh_terms: D000328:Adult; D000368:Aged; D015331:Cohort Studies; D005260:Female; D017052:Hospital Mortality; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000175:diagnosis / Q000401:mortality / Q000601:surgery*; D062645:Percutaneous Coronary Intervention / Q000401:mortality*; D011379:Prognosis; D012720:Severity of Illness Index; D016896:Treatment Outcome
keywords: CHA2DS2-VASc score; long-term; mortality; myocardial infarction