title: The impact of surgical resection on headache disability and quality of life in patients with colloid cyst.
abstract: Introduction Colloid cysts are histologically benign but can present with a broad spectrum of symptoms. A systematic review of the literature did not reveal any patient-centered data on the headache disability and quality of life (QoL) of these patients. Methods This is a retrospective cohort study of 187 colloid cyst patients from the Colloid Cyst Survival Group who completed a survey that included demographic data, clinical data, a modified QoL survey (SF36v2), and a headache disability inventory or index (HDI). Results Using multivariable linear regressions, we confirmed that the physical (PCS) and mental (MCS) components of SF-36 were significantly increased in the surgery group after adjustment for various baseline characteristics ( p = 0.025; p = 0.006). Self-reported headache disability was significantly decreased with surgery when adjusted for the same baseline characteristics ( p = 0.02). Finally, patients with an incidental diagnosis of colloid cyst reported similar benefits from surgery in PCS, MCS and HDI. Conclusion Our results suggest that colloid cyst patients who underwent a surgical resection self-report a better QoL and less headache disability compared with patients who did not undergo surgery. Future prospective studies with baseline measures of QoL are indicated to confirm our findings.
authors.affiliation: 1 Department of Neurosurgery, Johns Hopkins University, USA.
authors.forename: Lyonell
authors.initials: L
authors.lastname: Kone
authors.affiliation: 1 Department of Neurosurgery, Johns Hopkins University, USA.
authors.forename: Kaisorn L
authors.initials: KL
authors.lastname: Chaichana
authors.affiliation: 1 Department of Neurosurgery, Johns Hopkins University, USA.
authors.forename: Jordina
authors.initials: J
authors.lastname: Rincon-Torroella
authors.affiliation: 1 Department of Neurosurgery, Johns Hopkins University, USA.
authors.forename: Claire
authors.initials: C
authors.lastname: Snyman
authors.affiliation: 2 Department of Neurology, Johns Hopkins University, USA.
authors.forename: Abhay
authors.initials: A
authors.lastname: Moghekar
authors.affiliation: 1 Department of Neurosurgery, Johns Hopkins University, USA.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Quiñones-Hinojosa
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015331:Cohort Studies; D056364:Colloid Cysts / Q000150:complications / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006261:Headache / Q000000981:diagnostic imaging* / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D020542:Third Ventricle / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome; D055815:Young Adult
keywords: Colloid cyst; HDI; SF-36; headaches; quality of life; surgery