title: Multiple cranial neuropathies following etanercept administration.
abstract: There have been recent reports of sarcoid-like granulomatosis development following the administration of tumor necrosis factor (TNF) inhibitors. To date, only four cases of neurosarcoidosis have been reported in association with TNF inhibitors, two of which were attributed to etanercept. We present the first case of etanercept-induced neurosarcoidosis involving multiple cranial neuropathies, including the trigeminal, facial, and vestibulocochlear nerves, while also highlighting the differential diagnoses of multiple cranial neuropathies and the association of TNF inhibitors and neurosarcoidosis.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN USA.
authors.forename: Jacob B
authors.initials: JB
authors.lastname: Hunter
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN USA. Electronic address: alejandro.rivas@vanderbilt.edu.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Rivas
mesh_terms: D018501:Antirheumatic Agents / Q000009:adverse effects*; D001172:Arthritis, Rheumatoid / Q000000981:diagnostic imaging*; D002493:Central Nervous System Diseases / Q000175:diagnosis*; D003389:Cranial Nerve Diseases / Q000139:chemically induced* / Q000175:diagnosis; D000068800:Etanercept / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged; D012507:Sarcoidosis / Q000175:diagnosis*
chemical_list: D018501:Antirheumatic Agents; D000068800:Etanercept