title: Registration of Real-Time 3-D Ultrasound to Tomographic Images of the Abdominal Aorta.
abstract: The purpose of this study was to develop an image-based method for registration of real-time 3-D ultrasound to computed tomography (CT) of the abdominal aorta, targeting future use in ultrasound-guided endovascular intervention. We proposed a method in which a surface model of the aortic wall was segmented from CT, and the approximate initial location of this model relative to the ultrasound volume was manually indicated. The model was iteratively transformed to automatically optimize correspondence to the ultrasound data. Feasibility was studied using data from a silicon phantom and in vivo data from a volunteer with previously acquired CT. Through visual evaluation, the ultrasound and CT data were seen to correspond well after registration. Both aortic lumen and branching arteries were well aligned. The processing was done offline, and the registration took approximately 0.2 s per ultrasound volume. The results encourage further patient studies to investigate accuracy, robustness and clinical value of the approach.
authors.affiliation: Department of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; Department of Medical Technology, SINTEF, Trondheim, Norway; Norwegian National Advisory Unit on Ultrasound and Image-Guided Therapy, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway. Electronic address: reidar.brekken@sintef.no.
authors.forename: Reidar
authors.initials: R
authors.lastname: Brekken
authors.affiliation: Department of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; Department of Medical Technology, SINTEF, Trondheim, Norway; Norwegian National Advisory Unit on Ultrasound and Image-Guided Therapy, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
authors.forename: Daniel Høyer
authors.initials: DH
authors.lastname: Iversen
authors.affiliation: Department of Medical Technology, SINTEF, Trondheim, Norway; Norwegian National Advisory Unit on Ultrasound and Image-Guided Therapy, St. Olavs Hospital - Trondheim University Hospital, Trondheim, Norway.
authors.forename: Geir Arne
authors.initials: GA
authors.lastname: Tangen
authors.affiliation: Department of Circulation and Medical Imaging, NTNU, Norwegian University of Science and Technology, Trondheim, Norway; St. Olavs Hospital, Department of Vascular Surgery, Trondheim, Norway.
authors.forename: Torbjørn
authors.initials: T
authors.lastname: Dahl
mesh_terms: D000328:Adult; D001012:Aorta, Abdominal / Q000033:anatomy & histology*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008297:Male; D019047:Phantoms, Imaging; D012016:Reference Values; D014057:Tomography, X-Ray Computed / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*
keywords: Aneurysm; Aorta; Endovascular; Image-guidance; Intervention; Multimodal; Registration; Ultrasound