title: [Benefit of post-circumcision application of skin wound induction gel in the treatment of phimosis in children].
abstract: OBJECTIVE
  To study the effects of skin wound induction gel on the glans scabbing rate, class-A wound healing rate, and wound healing time of circumcision for phimosis in pediatric patients.
  
  
  METHODS
  We randomly assigned 48 six to thirteen years old children with phimosis to an experimental group (n = 25) and a control group (n = 23) to be treated by circumcision. After surgery, the patients in the experimental group received application of skin wound induction gel while those in the control group received that of povidone iodine only to the glans and incision. We recorded and compared the glans scabbing rate, class-A wound healing rate, and wound healing time between the two groups of patients.
  
  
  RESULTS
  Glans scabbing was observed in 3 cases in the experimental group and 17 cases in the control group (12.0% vs 73.9%, P < 0.01). No statistically significant differences were found in the rate of class-A wound healing between the two groups (100% vs 91.3%, P > 0.05). The wound healing time was significantly shorter in the experimental than in the control group ([10.7 ± 1.7] d vs [11.9 ± 2.1] d, P < 0.05).
  
  
  CONCLUSIONS
  Post-circumcision application of skin wound induction gel to the glans and incision can effectively reduce glans secreta, alleviate inflammatory reaction, and shorten the healing time in the treatment of phimosis in children.
authors.forename: Yong-liang
authors.initials: YL
authors.lastname: Ni
authors.forename: Hai-xin
authors.initials: HX
authors.lastname: Wang
authors.forename: Yan
authors.initials: Y
authors.lastname: Xu
authors.forename: Shou-bin
authors.initials: SB
authors.lastname: Jiao
mesh_terms: D000293:Adolescent; D002648:Child; D002944:Circumcision, Male; D005782:Gels / Q000008:administration & dosage; D006801:Humans; D060828:Induction Chemotherapy / Q000379:methods; D007249:Inflammation / Q000517:prevention & control; D008297:Male; D010688:Phimosis / Q000188:drug therapy*; D011183:Postoperative Complications / Q000517:prevention & control; D014945:Wound Healing / Q000187:drug effects*
chemical_list: D005782:Gels