title: [Patients with sepsis].
abstract: Sepsis is still the leading cause of mortality in noncardiac intensive care units. The new definition of sepsis emphasizes the importance of organ dysfunction. The Sepsis-related Organ Failure Assessment (SOFA) score is an indicator for organ dysfunction. The diagnosis of sepsis is for the most part made on clinical parameters with an altered mental status being a very sensitive indicator. Microbiological work-up is essential and two sets of blood cultures are the recommended minimum. Management includes prompt initiation of adequate antibiotic treatment and swift fluid resuscitation. Overinfusion is to be avoided as this itself can have a negative impact on patient outcome.
authors.affiliation: Klinik für Notfall- und Intensivmedizin, Klinikum Ernst von Bergmann, Charlottenstraße 72, 14467, Potsdam, Deutschland. moppert@klinikumevb.de.
authors.forename: M
authors.initials: M
authors.lastname: Oppert
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001431:Bacteriological Techniques; D042241:Early Diagnosis; D061345:Early Medical Intervention; D006801:Humans; D007362:Intensive Care Units; D009102:Multiple Organ Failure / Q000175:diagnosis / Q000628:therapy; D011379:Prognosis; D018805:Sepsis / Q000175:diagnosis* / Q000628:therapy*; D012772:Shock, Septic / Q000175:diagnosis / Q000628:therapy
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotics; Diagnosis; Disease management; Sepsis; Septic shock