title: Indications for adjuvant radiation therapy in breast cancer: a review of the evidence and recommendations for clinical practice.
abstract: Radiation therapy (RT) plays an important role in the curative management of all stages of breast cancer. The optimal application of adjuvant RT is an area of continuous investigation, and the indications for treatment are refined with each new trial. This article reviews the evidence for adjuvant RT across five distinct clinical scenarios, with additional discussion of RT targets, techniques, and doses where appropriate.
authors.affiliation: Department of Radiation Oncology, MD Anderson Cancer Center, Houston, Texas, USA.
authors.forename: Cameron W
authors.initials: CW
authors.lastname: Swanick
authors.affiliation: Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Boulevard, Unit 1202, Houston, TX, 77030, USA. Email: bsmith3@mdanderson.org.
authors.forename: Benjamin D
authors.initials: BD
authors.lastname: Smith
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy*; D003657:Decision Making; D005260:Female; D006801:Humans; D018714:Radiotherapy, Adjuvant / Q000379:methods; D016032:Randomized Controlled Trials as Topic
keywords: Breast cancer; clinical decision-making; radiation