title: RFID Tag Helix Antenna Sensors for Wireless Drug Dosage Monitoring.
abstract: Miniaturized helix antennas are integrated with drug reservoirs to function as RFID wireless tag sensors for real-time drug dosage monitoring. The general design procedure of this type of biomedical antenna sensors is proposed based on electromagnetic theory and finite element simulation. A cost effective fabrication process is utilized to encapsulate the antenna sensor within a biocompatible package layer using PDMS material, and at the same time form a drug storage or drug delivery unit inside the sensor. The in vitro experiment on two prototypes of antenna sensor-drug reservoir assembly have shown the ability to monitor the drug dosage by tracking antenna resonant frequency shift from 2.4-2.5-GHz ISM band with realized sensitivity of 1.27 [Formula: see text] for transdermal drug delivery monitoring and 2.76-[Formula: see text] sensitivity for implanted drug delivery monitoring.
authors.affiliation: Methodist Hospital Research InstituteHoustonTXUSA77030; Department of Electrical and Computer EngineeringUniversity of Texas at AustinAustinTXUSA78712.
authors.forename: Haiyu
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Electrical and Computer EngineeringUniversity of Texas at AustinAustinTXUSA78712; Department of Electronic EngineeringTsinghua UniversityBeijingChina100084.
authors.forename: Peisen
authors.initials: P
authors.lastname: Zhao
authors.affiliation: Department of Electrical and Computer Engineering University of Texas at Austin Austin TX USA 78712.
authors.forename: Pai-Yen
authors.initials: PY
authors.lastname: Chen
authors.affiliation: Department of Electronic Engineering Tsinghua University Beijing China 100084.
authors.forename: Yong
authors.initials: Y
authors.lastname: Ren
authors.affiliation: Methodist Hospital Research Institute Houston TX USA 77030.
authors.forename: Xuewu
authors.initials: X
authors.lastname: Liu
authors.affiliation: Methodist Hospital Research Institute Houston TX USA 77030.
authors.forename: Mauro
authors.initials: M
authors.lastname: Ferrari
authors.affiliation: Methodist Hospital Research Institute Houston TX USA 77030.
authors.forename: Ye
authors.initials: Y
authors.lastname: Hu
authors.affiliation: Department of Electrical and Computer Engineering University of Texas at Austin Austin TX USA 78712.
authors.forename: Deji
authors.initials: D
authors.lastname: Akinwande
keywords: Drug delivery system; RFID; electrically small antenna; helix antenna; medical implants; wireless sensor