title: Hemophilia Therapy--Navigating Speed Bumps on the Innovation Highway.
authors.affiliation: From the Division of Blood Diseases, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD.
authors.forename: Donna M
authors.initials: DM
authors.lastname: DiMichele
mesh_terms: D018033:Antibodies, Bispecific / Q000627:therapeutic use*; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use*; D057134:Antibodies, Neutralizing / Q000097:blood*; D005169:Factor VIII / Q000037:antagonists & inhibitors* / Q000276:immunology*; D006467:Hemophilia A / Q000188:drug therapy*; D006470:Hemorrhage / Q000517:prevention & control*; D006801:Humans; D007518:Isoantibodies / Q000032:analysis*; D008297:Male; D014841:von Willebrand Factor / Q000627:therapeutic use*
chemical_list: D018033:Antibodies, Bispecific; D061067:Antibodies, Monoclonal, Humanized; D057134:Antibodies, Neutralizing; D007518:Isoantibodies; D014841:von Willebrand Factor; D005169:Factor VIII