title: [Verapamil in conjunction with pressure therapy in the treatment of pathologic scar due burn injury].
abstract: BACKGROUND
  Keloids and hypertrophic scars are dermal fibro-proliferative disorders unique to humans. Their treatment is a true challenge with multiple options, but not all the time with good results. Unfortunately this problem is not uncommon in patients with history of burn injury. The aim of this article is to evaluate the use of verapamil and pressure garments in patients with hypertrophic or keloid scar caused by burn injury.
  
  
  METHODS
  We included patients with a hypertrophic or keloid scar caused by burn injury candidate to treatment with pressure garment. The pathologic scars were evaluated by serial photographic records, Vancouver and Posas scales. The scales of Vancouver and Posas were compared with t Student.
  
  
  RESULTS
  We included 13 scars in 11 patients. Four scars were located in the legs, 4 in the arms, 4 in the face-neck and 1 in the abdomen. The dose of verapamil was calculated .03mg per kg. Injections were scheduled every 7 to 10 days until complete 6 sessions. Taking in count Posas scale, patients referred improvement in pigmentation (.01), thickness (.005), pliability (.01) and surface area (.004). In the Vancouver scale the observers mentioned improvement in elevation (.008), pigmentation (.014), vascularity (.022), flexibility (.014) and pruritus (.003). No adverse effects were found in verapamil injection.
  
  
  CONCLUSIONS
  Verapamil was useful in conjunction with pressure garment to improve the condition of the keloid and hypertrophic scar caused by burn.
authors.affiliation: Unidad de Atención al Niño Quemado, Nuevo Nuevo Hospital Civil de Guadalajara "Juan I. Menchaca", Guadalajara, Jalisco, México. guiyermoramos@hotmail.com.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Ramos-Gallardo
authors.forename: Ariel
authors.initials: A
authors.lastname: Miranda-Altamirano
authors.forename: Rebeca
authors.initials: R
authors.lastname: Valdes-López
authors.forename: Sandra
authors.initials: S
authors.lastname: Figueroa-Jiménez
authors.forename: Leonel
authors.initials: L
authors.lastname: García-Benavides
mesh_terms: D002056:Burns / Q000150:complications*; D002121:Calcium Channel Blockers / Q000627:therapeutic use*; D017439:Cicatrix, Hypertrophic / Q000209:etiology / Q000628:therapy*; D058128:Compression Bandages; D006801:Humans; D007627:Keloid / Q000209:etiology / Q000628:therapy*; D011446:Prospective Studies; D016896:Treatment Outcome; D014700:Verapamil / Q000627:therapeutic use*
chemical_list: D002121:Calcium Channel Blockers; D014700:Verapamil
keywords: Burns; Hypertrophic cicatrix; Keloid; Verapamil