title: Hypoxic-Ischemic Encephalopathy and Serum Magnesium Monitoring and Maintenance.
abstract: Magnesium plays important roles in many physiologic functions including protein synthesis, bone development, and cell membrane function. There is some evidence to suggest a role for magnesium sulfate as a therapeutic neuroprotective agent along with therapeutic hypothermia in infants with hypoxic-ischemic encephalopathy, but studies are inconclusive. Ischemic insult and hypothermia may both play a role in altered magnesium levels in this population.
authors.affiliation: Medical Center of Trinity.
authors.forename: Susan Givens
authors.initials: SG
authors.lastname: Bell
mesh_terms: D015415:Biomarkers / Q000097:blood; D003131:Combined Modality Therapy; D006801:Humans; D007036:Hypothermia, Induced; D020925:Hypoxia-Ischemia, Brain / Q000097:blood / Q000503:physiopathology / Q000628:therapy*; D007231:Infant, Newborn; D008274:Magnesium / Q000097:blood; D008275:Magnesium Deficiency / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology; D008278:Magnesium Sulfate / Q000627:therapeutic use*; D018696:Neuroprotective Agents / Q000627:therapeutic use*
chemical_list: D015415:Biomarkers; D018696:Neuroprotective Agents; D008278:Magnesium Sulfate; D008274:Magnesium