title: Clinical and functional comparison of endoprosthetic replacement with intramedullary nailing for treating proximal femur metastasis.
abstract: OBJECTIVE
  To evaluate the clinical and functional outcomes of modular endoprosthetic replacement (EPR) compared to proximal femur intramedullary nailing (IMN) for the treatment of proximal femur metastases.
  
  
  METHODS
  We retrospectively studied the records of patients with proximal femur metastatic lesions treated with surgical stabilization between January 2007 and December 2014 in terms of operation time, blood loss, postoperative score, soreness, Karnofsky performance score (KPS) and survival time.
  
  
  RESULTS
  There were 34 patients treated with surgical stabilization. The mean follow-up period was 12.1?.6 months (range: 10-47 months). Thirteen were treated with EPR and 21 were stabilized with IMN (20 males, 14 females; mean age: 68.7 years). The median survival time was 11.0 months for both groups (P=0.147). The operation time, blood loss and Harris score of IMN group were lower than those of EPR group (P=0.001, P=0.001, P=0.002, respectively).
  
  
  CONCLUSIONS
  Both EPR and IMN for treating proximal femur metastasis achieved effective clinical outcomes. Therefore, the suitable surgical methods depended on the general conditions and medical requirements of patients, as well as the technical advantages of the doctor.
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Gao
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Zhenyu
authors.initials: Z
authors.lastname: Liu
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Baojun
authors.initials: B
authors.lastname: Wang
authors.affiliation: Department of Orthopedics, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
authors.forename: Ai
authors.initials: A
authors.lastname: Guo
keywords: Proximal femur; bone metastasis; endoprosthetic replacement; intramedullary nailing (IMN)