title: The benefit of HH during the CPAP titration in the cool sleeping environment.
abstract: OBJECTIVE
  Upper airway symptom associated with continuous positive airway pressure (CPAP) treatment is an important factor influencing CPAP adherence. There are conflicting data on the effect of a heated humidifier (HH) during CPAP titration for patients with obstructive sleep apnea hypopnea syndrome (OSAHS). This study investigated the effects of HH during CPAP titration in the cool sleeping environment.
  
  
  METHODS
  Forty newly diagnosed OSAHS patients who received CPAP titration in the cool sleeping environment were randomly assigned to HH and non-HH groups. A questionnaire was used to evaluate upper airway symptoms, satisfaction with initial CPAP treatment, and willingness to further use CPAP. Some therapy parameters including leak, apnea hypopnea index (AHI) reduction, and optimal CPAP pressure level were analyzed. We compared these subjective and objective data between the two groups.
  
  
  RESULTS
  In subjective sensation, the use of HH can alleviate upper airway symptoms associated with CPAP titration (P < 0.001). The HH group has benefit in satisfaction with initial CPAP treatment (P < 0.001) and further willingness to use CPAP (P < 0.01), although there were no significant differences in leak, AHI reduction, and optimal CPAP pressure between the two groups.
  
  
  CONCLUSIONS
  The use of HH is recommended during CPAP titration in the cool sleeping environment because of its benefit in the treatment of upper airway symptoms associated with CPAP therapy and improvement of the CPAP acceptance.
authors.affiliation: Department of Emergency, The Third Xiangya Hospital of Central South University, Tong-ZiPo Road No.138, Changsha, Hunan, 410013, People's Republic of China.
authors.forename: Yayong
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Geriatrics, The Second Xiangya Hospital of Central South University, Middle Ren-Min Road No.139, Changsha, Hunan, 410011, People's Republic of China. angela780415@163.com.
authors.forename: Yina
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000328:Adult; D002138:Calibration; D002681:China; D003080:Cold Temperature; D045422:Continuous Positive Airway Pressure / Q000295:instrumentation / Q000379:methods* / Q000523:psychology; D005260:Female; D006361:Heating; D006801:Humans; D000068998:Humidifiers; D008297:Male; D008875:Middle Aged; D010349:Patient Compliance; D017060:Patient Satisfaction; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D012894:Sleep Stages
keywords: Continuous positive airway pressure; Heated humidifier; Obstructive sleep apnea hypopnea syndrome