title: Primary Mucosa-associated Lymphoid Tissue Lymphoma Metachronously Involving Esophagus and Stomach.
abstract: Mucosa-associated lymphoid tissue (MALT) lymphoma is found in various organs as extranodal B cell lymphoma. The gastro-intestinal tract is the most commonly involved extranodal site in MALT lymphoma. However, primary esophageal MALT lymphoma is very rare. In addition, few cases with metachronous gastric involvement have been reported. A 55-year-old man was diagnosed with MALT lymphoma by surveillance esop hagogastroduodenoscopy. A 5 cm esophageal submucosal tumor-like lesion was incidentally revealed by screening esophagogastroduodenoscopy two years prior. Esophagogastroduodenoscopy showed a cylin-drically elongated submucosal mass with normal overlying mucosa in the mid esophagus. He underwent surgery to confirm the diagnosis. The pathologic diagnosis was esophageal MALT lymp homa. He was treated with radiation, which achieved complete remission. Esophagogastroduodenoscopy and chest computed tomography were performed every three to six months, with no evidence of recurrence for 18 months. After 21 months, severa l elevated gastric erosions were found on the great curvature and posterior sides of the midbody and confirmed as MALT lymphoma pathologically. Here we report a case with MALT lymphoma metachronously involving the esophagus and stomach.
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Seung Joo
authors.initials: SJ
authors.lastname: Byun
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Hyoun Woo
authors.initials: HW
authors.lastname: Kang
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Joo Kyoung
authors.initials: JK
authors.lastname: Cha
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Soo Ryeong
authors.initials: SR
authors.lastname: Ryoo
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Jeong Hyeon
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Do Yeon
authors.initials: DY
authors.lastname: Kim
authors.affiliation: Department of Pathology, Dongguk University Ilsan Hospital, Goyang, Korea.
authors.forename: Eo Jin
authors.initials: EJ
authors.lastname: Kim
mesh_terms: D018951:Antigens, CD20; D016145:Endoscopy, Digestive System; D000071041:Esophageal Mucosa / Q000473:pathology; D004938:Esophageal Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D005753:Gastric Mucosa / Q000473:pathology; D006801:Humans; D007150:Immunohistochemistry; D018442:Lymphoma, B-Cell, Marginal Zone / Q000175:diagnosis* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D014057:Tomography, X-Ray Computed
chemical_list: D018951:Antigens, CD20
keywords: Esophagus; Marginal zone B-cell lymphoma; Metachronous; Stomach