title: What's Hot in Schizophrenia Research?
abstract: Schizophrenia is a heterogeneous psychiatric illness for which the cause or causes are presently unknown. There is increasing evidence from multiple levels of research suggesting that inflammation may play an important role in the development and persistence of psychosis and cognitive impairment in a proportion of people with schizophrenia. This overview of recent literature focuses on studies of neuroinflammation that are considered to be of increasing interest in schizophrenia research and are poised to have an impact on the cause, diagnosis, and potential treatment of at least some forms or subtypes of schizophrenia.
authors.affiliation: Schizophrenia Research Institute, Barker Street, Randwick, New South Wales 2031, Australia; School of Psychiatry, University of New South Wales, Hospital Road, Randwick, New South Wales 2031, Australia; Neuroscience Research Australia, Barker Street, Randwick, New South Wales 2031, Australia. Electronic address: cyndi@neura.edu.au.
authors.forename: Cynthia Shannon
authors.initials: CS
authors.lastname: Weickert
authors.affiliation: Schizophrenia Research Institute, Barker Street, Randwick, New South Wales 2031, Australia; School of Psychiatry, University of New South Wales, Hospital Road, Randwick, New South Wales 2031, Australia; Neuroscience Research Australia, Barker Street, Randwick, New South Wales 2031, Australia. Electronic address: t.weickert@unsw.edu.au.
authors.forename: Thomas W
authors.initials: TW
authors.lastname: Weickert
mesh_terms: D001344:Autopsy; D015415:Biomarkers / Q000378:metabolism; D055106:Genome-Wide Association Study; D006801:Humans; D007249:Inflammation / Q000150:complications / Q000235:genetics / Q000378:metabolism; D059906:Neuroimaging / Q000379:methods; D012106:Research / Q000639:trends*; D012559:Schizophrenia / Q000209:etiology* / Q000235:genetics / Q000473:pathology*
chemical_list: D015415:Biomarkers
keywords: Biomarkers; Cytokines; Inflammation; Microglia; Psychosis; Schizophrenia; Ultra-high risk