title: Data on IL-17 production induced by plant lectins.
abstract: We reported in article da Silva et al. (2016) [2] that ArtinM induces the IL-17 production through interaction with CD4(+) T cells and stimulation of IL-23 and IL-1. Besides ArtinM, other plant lectins (PLs) induce IL-17 production by murine spleen cells. The IL-17 production induced by PLs was evaluated regarding the involvement of IL-23, IL-6, Th1-, and Th2-cytokines. Furthermore, the effect exerted TLR2, TLR4, and CD14 on the PLs׳ performance in the induction of IL-17 was examined. The current data were compared to the known ArtinM ability to induce Th17 immunity.
authors.affiliation: Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.
authors.forename: Thiago Aparecido
authors.initials: TA
authors.lastname: da Silva
authors.affiliation: Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.
authors.forename: Fabrício Freitas
authors.initials: FF
authors.lastname: Fernandes
authors.affiliation: Departamento de Biologia Celular e Molecular e Bioagentes Patogênicos, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brazil.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Roque-Barreira
keywords: ArtinM; Carbohydrate recognition; IL-17; Immunomodulation; Plant lectins