title: Prostate cancer post-treatment follow-up and recurrence evaluation.
abstract: Recurrent prostate cancer following primary treatment is common, and the population of men with biochemical recurrence is complex. Conventional management of recurrent prostate cancer involves nontargeted and/or systemic therapies, without defining an individual patient's specific disease. However, recent advances in imaging enable a shift in the management of recurrent prostate cancer to targeted, patient-specific approaches. Specifically, MRI can detect and define local prostate cancer recurrence early in the course of disease, and prostate-specific PET imaging greatly improves nodal staging and can detect previously unknown distant metastases. The significant advances in the imaging of both local and distant tumor recurrences allows for specific selection of treatment options tailored to patients and their disease with less associated morbidity.
authors.affiliation: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. may.eric@mayo.edu.
authors.forename: Eric J
authors.identifier: 0000-0003-0752-730X
authors.initials: EJ
authors.lastname: May
authors.affiliation: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
authors.forename: Lyndsay D
authors.initials: LD
authors.lastname: Viers
authors.affiliation: Department of Urology, Mayo Clinic, Rochester, MN, USA.
authors.forename: Boyd R
authors.initials: BR
authors.lastname: Viers
authors.affiliation: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
authors.forename: Akira
authors.initials: A
authors.lastname: Kawashima
authors.affiliation: Department of Urology, Mayo Clinic, Rochester, MN, USA.
authors.forename: Eugene D
authors.initials: ED
authors.lastname: Kwon
authors.affiliation: Department of Urology, Mayo Clinic, Rochester, MN, USA.
authors.forename: R Jeffrey
authors.initials: RJ
authors.lastname: Karnes
authors.affiliation: Department of Radiology, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
authors.forename: Adam T
authors.initials: AT
authors.lastname: Froemming
mesh_terms: D003287:Contrast Media; D006801:Humans; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging* / Q000473:pathology*; D009367:Neoplasm Staging; D000072078:Positron Emission Tomography Computed Tomography; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology* / Q000628:therapy; D019275:Radiopharmaceuticals; D012307:Risk Factors
chemical_list: D003287:Contrast Media; D019275:Radiopharmaceuticals
keywords: Biochemical recurrence; C-11 choline PET/CT; MRI; Prostate cancer