title: Biomedical Applications of Terahertz Spectroscopy and Imaging.
abstract: Terahertz (THz=10(12)Hz) radiation has attracted wide attention for its unprecedented sensing ability and its noninvasive and nonionizing properties. Tremendous strides in THz instrumentation have prompted impressive breakthroughs in THz biomedical research. Here, we review the current state of THz spectroscopy and imaging in various biomedical applications ranging from biomolecules, including DNA/RNA, amino acids/peptides, proteins, and carbohydrates, to cells and tissues. We also address the potential biological effects of THz radiation during its biological applications and propose future prospects for this cutting-edge technology.
authors.affiliation: Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China; Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Zhao
authors.affiliation: Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China; Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Yang
authors.affiliation: Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Yueping
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Laboratory Medicine, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Electronic address: fwl@tmmu.edu.cn.
authors.forename: Weiling
authors.initials: W
authors.lastname: Fu
authors.affiliation: Medical Research Center, Southwest Hospital, Third Military Medical University, Chongqing 400038, China. Electronic address: luoyang@tmmu.edu.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Luo
mesh_terms: D000596:Amino Acids / Q000032:analysis / Q000737:chemistry; D000818:Animals; D001419:Bacteria; D002241:Carbohydrates / Q000032:analysis / Q000737:chemistry; D003584:Cytological Techniques; D004247:DNA / Q000032:analysis / Q000737:chemistry; D003952:Diagnostic Imaging; D006801:Humans; D051379:Mice; D011506:Proteins / Q000032:analysis / Q000737:chemistry; D012867:Skin / Q000000981:diagnostic imaging; D055068:Terahertz Spectroscopy
chemical_list: D000596:Amino Acids; D002241:Carbohydrates; D011506:Proteins; D004247:DNA
keywords: THz; biological effect; biomedical research; imaging; spectroscopy; terahertz