title: Blood Donor Screening for West NiIe Virus in Oklahoma and Its Contribution to Disease Surveillance, 2003 -2013.
abstract: Upon recognition that West Nile virus (WNV) was transmissible by transfusion, universal testing of blood donors by nucleic acid testing (NAT) was initiated in 2003. A retrospective review of 2003-2013 blood donor records and public health surveillance data in Oklahoma was undertaken to determine the percentage of WNV-positive blood donors who developed clinical symptoms post-donation and to examine the incidence and timing of WNV viremic donors in the context of WNV disease reported statewide. Among all WNV NAT-positive blood donors, 19% had self-described symptoms consistent with WNV disease. A viremic blood donor was the seasonal index case of WNV transmission in Oklahoma during one year [2006] of the study period. Blood donors remain an important surveillance component for epidemiologic monitoring of WNV in Oklahoma.
authors.forename: Walter E
authors.initials: WE
authors.lastname: Kelley
authors.forename: Kristy
authors.initials: K
authors.lastname: Bradley
authors.forename: Ashten
authors.initials: A
authors.lastname: Duncan
authors.forename: James
authors.initials: J
authors.lastname: Smith
mesh_terms: D000328:Adult; D000368:Aged; D000818:Animals; D001782:Blood Donors / Q000706:statistics & numerical data*; D001803:Blood Transfusion; D016358:Contact Tracing / Q000379:methods; D009033:Culicidae / Q000821:virology; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods / Q000706:statistics & numerical data; D008875:Middle Aged; D009825:Oklahoma / Q000453:epidemiology; D011159:Population Surveillance; D011634:Public Health / Q000706:statistics & numerical data; D016036:Seroepidemiologic Studies; D014901:West Nile Fever / Q000097:blood / Q000175:diagnosis / Q000453:epidemiology / Q000517:prevention & control; D014902:West Nile virus / Q000235:genetics / Q000302:isolation & purification