title: Giant Cell Tumor Bone in an Elderly Male- an Unusual Case Misdiagnosed on MRI as a Malignant Sarcoma.
abstract: Giant cell tumor (GCT) of the bone is a benign locally aggressive neoplasm which accounts for 3-8 % of all primary bone tumors. 60-70 % of the patients with giant cell tumor of the bone occur in the age group of 20-40 years. Patients older than 55 years of age very rarely develop GCT. Although many case series have been published on giant cell tumor of the bone, even on extensive search of literature, we found only a single series of 10 cases focusing exclusively on giant cell tumors in elderly. They observed that there was no difference in behavior of GCT in elderly and younger patients in terms of location of tumor, radiographic features and clinical course. We present a case of GCT of tibia in an elderly male without any evidence of malignant transformation or dedifferentiation, despite magnetic resonance imaging revealing features of a malignant lesion.
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, New Delhi, 110062 India.
authors.forename: Mukta
authors.initials: M
authors.lastname: Pujani
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, New Delhi, 110062 India.
authors.forename: Shalini
authors.initials: S
authors.lastname: Bahadur
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, New Delhi, 110062 India.
authors.forename: Zeeba S
authors.initials: ZS
authors.lastname: Jairajpuri
authors.affiliation: Department of Pathology, Hamdard Institute of Medical Sciences and Research, New Delhi, 110062 India.
authors.forename: Sujata
authors.initials: S
authors.lastname: Jetley
authors.affiliation: Department of Orthopedics, Hamdard Institute of Medical Sciences and Research, New Delhi, India.
authors.forename: Javed
authors.initials: J
authors.lastname: Jameel
keywords: Bone tumor; Elderly; Giant cell tumor