title: ACUTE SEROUS RETINAL DETACHMENT IN IDIOPATHIC PULMONARY ARTERIAL HYPERTENSION.
abstract: OBJECTIVE
  To report the case of a 44-year-old woman with acute transient visual loss likely because of idiopathic pulmonary arterial hypertension.
  
  
  METHODS
  Case report imaged with fundus photographs, spectral-domain optical coherence tomography, fundus autofluorescence, and fluorescein and indocyanine green angiographies.
  
  
  RESULTS
  The patient complained of unilateral vision loss with metamorphopsia. Fundus examination of the right eye showed serous macular detachment and retinal folds. Fluorescein angiography and indocyanine green angiography showed delayed choroidal filling with multiple choroidal perfusion defects and dye leakage from areas of multiple pigment epithelial detachments. Spectral-domain optical coherence tomography showed a thick choroid. Medical history included idiopathic pulmonary arterial hypertension treated with tadalafil. Ocular signs regressed spontaneously within 1 week.
  
  
  CONCLUSIONS
  Transient severe choroidal filling defects with subretinal exudation may be observed in idiopathic pulmonary arterial hypertension. The present case raised the questions of the triggering factor of the acute decompensation of the blood-retinal barrier and the cause of its spontaneous regression.
authors.affiliation: *Department of Ophthalmology, Centre Hospitalier Intercommunal de Créteil, Université Paris Est, Paris, France; and †The Centre Ophtalmologique d'Imagerie et de Laser, Paris, France.
authors.forename: David
authors.initials: D
authors.lastname: Martiano
authors.forename: Olivier
authors.initials: O
authors.lastname: Chevreaud
authors.forename: Delphine
authors.initials: D
authors.lastname: Lam
authors.forename: Salomon Y
authors.initials: SY
authors.lastname: Cohen
authors.forename: Eric H
authors.initials: EH
authors.lastname: Souied
mesh_terms: D000208:Acute Disease; D000328:Adult; D065627:Familial Primary Pulmonary Hypertension / Q000150:complications*; D005260:Female; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006801:Humans; D012163:Retinal Detachment / Q000175:diagnosis / Q000209:etiology*; D041623:Tomography, Optical Coherence; D014792:Visual Acuity