title: Fatal nosocomial meningitis caused by Mycoplasma hominis in an adult patient: case report and review of the literature.
abstract: Meningitis due to Mycoplasma hominis in adults is rarely described, with only three cases having been reported to date. A case of fatal meningitis in a 39-year-old patient after a neurosurgical procedure for a subarachnoid haemorrhage is reported herein. Identification and treatment were significantly delayed because of the rarity of the aetiology and difficulty identifying this organism with the routinely used conventional methods, such as Gram staining and agar growth on standard agar plates. Clinical procedures and the treatment of 'culture-negative' central nervous system infections is a real challenge for clinical microbiologists and clinicians, and M. hominis has to be considered as a potential, although very uncommon, pathogen.
authors.affiliation: Department of Microbiology, CHU de Caen, Av. Côte de Nacre, 14033 Caen Cedex 9, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Reissier
authors.affiliation: Department of Anaesthesiology and Critical Care Medicine, CHU de Caen, Caen, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Masson
authors.affiliation: Department of Microbiology, CHU de Caen, Av. Côte de Nacre, 14033 Caen Cedex 9, France.
authors.forename: François
authors.initials: F
authors.lastname: Guérin
authors.affiliation: Department of Anaesthesiology and Critical Care Medicine, CHU de Caen, Caen, France.
authors.forename: Gérald
authors.initials: G
authors.lastname: Viquesnel
authors.affiliation: Department of Virology, CHU de Caen, Caen, France.
authors.forename: Joëlle
authors.initials: J
authors.lastname: Petitjean-Lecherbonnier
authors.affiliation: University of Bordeaux, INRA, USC EA 3671 Mycoplasma and Chlamydia Infections in Humans, Bordeaux, France; Department of Bacteriology, CHU de Bordeaux, Bordeaux, France.
authors.forename: Sabine
authors.initials: S
authors.lastname: Pereyre
authors.affiliation: Department of Microbiology, CHU de Caen, Av. Côte de Nacre, 14033 Caen Cedex 9, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Cattoir
authors.affiliation: Department of Microbiology, CHU de Caen, Av. Côte de Nacre, 14033 Caen Cedex 9, France. Electronic address: isnard-c@chu-caen.fr.
authors.forename: Christophe
authors.initials: C
authors.lastname: Isnard
mesh_terms: D000328:Adult; D003428:Cross Infection / Q000401:mortality*; D017809:Fatal Outcome; D006801:Humans; D008297:Male; D016920:Meningitis, Bacterial / Q000401:mortality*; D009175:Mycoplasma Infections / Q000401:mortality*; D019535:Mycoplasma hominis; D013345:Subarachnoid Hemorrhage / Q000601:surgery
keywords: Central nervous system; Meningitis; Molecular identification; Mycoplasma hominis; Nosocomial