title: Development of dummy molecularly imprinted based on functionalized silica nanoparticles for determination of acrylamide in processed food by matrix solid phase dispersion.
abstract: A novel technique was applied for the synthesis of dummy molecularly imprinted silica nanoparticles (DMISNPs). DMISNPs were characterized by Fourier transmission infrared spectrometry, scanning electron microscopy and transmission electron microscope. The material was used as dispersant for the analysis of biscuit and bread samples using matrix solid phase dispersion (MSPD). Of advantages of such approach may be counted as the simplicity of synthesis procedure, low consumption of organic solvent, mild working temperature during the synthesis, high binding capacity and affinity. The effect of various parameters such as sample-to-dispersant ratio and eluents volume on extraction recovery was investigated and optimized by central composite design under response surface methodology. It was proven that the proposed dispersant leads to high affinity toward acrylamide even in complicated matrices. Quantification of the acrylamide was carried out by high performance liquid chromatography with UV detection (HPLC-UV).
authors.affiliation: Chemistry Department, Yasouj University, Yasouj 75914-35, Iran.
authors.forename: Maryam
authors.initials: M
authors.lastname: Arabi
authors.affiliation: Chemistry Department, Yasouj University, Yasouj 75914-35, Iran. Electronic address: m_ghaedi@mail.yu.ac.ir.
authors.forename: Mehrorang
authors.initials: M
authors.lastname: Ghaedi
authors.affiliation: Department of Chemistry, Kerman Branch, Islamic Azad University, Kerman, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Ostovan
mesh_terms: D020106:Acrylamide / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D005506:Food Contamination / Q000032:analysis*; D008855:Microscopy, Electron, Scanning; D054802:Molecular Imprinting / Q000379:methods*; D053758:Nanoparticles / Q000737:chemistry*; D012822:Silicon Dioxide / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000379:methods*
chemical_list: D020106:Acrylamide; D012822:Silicon Dioxide
keywords: Acrylamide; Dummy template; Matrix solid phase dispersion; Molecularly imprinted; Silica nanoparticles