title: Zika virus update II: Recent development of animal models-Proofs of association with human pathogenesis.
abstract: Three recent studies in pregnant mice and one ongoing study in rhesus macaques evaluating the effect of ZIKV infection have provided important information about maternal-fetus transmission and ZIKV-related pathogenesis, confirming a causal role of ZIKV in neurological problems observed in humans. Here, we present an update of these works published in the past few weeks. J. Med. Virol. 88:1657-1658, 2016. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California.
authors.forename: Suzane
authors.initials: S
authors.lastname: Ramos da Silva
authors.affiliation: Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California.
authors.forename: Shou-Jiang
authors.initials: SJ
authors.lastname: Gao
mesh_terms: D000818:Animals; D004195:Disease Models, Animal; D005260:Female; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D008253:Macaca mulatta; D051379:Mice; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000821:virology*; D000071244:Zika Virus / Q000472:pathogenicity*; D000071243:Zika Virus Infection / Q000150:complications / Q000635:transmission* / Q000821:virology*
keywords: Zika virus; animal model; pathology