title: Vascular access for extracorporeal life support: tips and tricks.
abstract: In thoracic surgery, extracorporeal life support (ECLS) techniques are performed to (I) provide a short to mid term extracorporeal mechanical support; (II) realize the gas exchanges; and (III)-depending the configuration of the circuit-substitute the failed heart function. The objective of this review is to describe the rational of the different ECLS techniques used in thoracic surgery and lung transplantation (LTx) with a specific attention to the vascular access. Venovenous extracorporeal membrane oxygenation (VV ECMO) is the most common ECLS technique used in thoracic surgery and represents the best strategy to support the lung function. VV ECMO needs peripheral vascular access. The selection between his double-site or single-site configuration should be decided according the level of O2 requirements, the nosological context, and the interest to perform an ECLS ambulatory strategy. Venoarterial (VA) ECMO uses peripheral and/or central cannulation sites. Central VA ECMO is mainly used in LTx instead a conventional cardiopulmonary bypass (CPB) to decrease the risk of hemorrhagic issues and the rate of primary graft dysfunction (PGD). Peripheral VA ECMO is traditionally realized in a femoro-femoral configuration. Femoro-femoral VA ECMO allows a cardiocirculatory support but does not provide an appropriate oxygenation of the brain and the heart. The isolated hypercapnic failure is currently supported by extracorporeal CO2 removal (ECCO2R) devices inserted in jugular or subclavian veins. The interest of the Novalung (Novalung GmbH, Hechingen, Germany) persists due to his central configuration indicated to bridge to LTx patients suffering from pulmonary hypertension. The increasing panel of ECLS technologies available in thoracic surgery is the results of a century of clinical practices, engineering progress, and improvements of physiological knowledges. The selection of the ECLS technique-and therefore the vascular access to implant the device-for a given nosological context trends to be defined according an evidence-based medicine.
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Jeremie
authors.initials: J
authors.lastname: Reeb
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Olland
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Stephane
authors.initials: S
authors.lastname: Renaud
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Anne
authors.initials: A
authors.lastname: Lejay
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Nicola
authors.initials: N
authors.lastname: Santelmo
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Gilbert
authors.initials: G
authors.lastname: Massard
authors.affiliation: 1 Division of Thoracic Surgery and Strasbourg Lung Transplant Program, 2 Division of Vascular Surgery and Kidney Transplantation, Strasbourg University Hospital, 1 place de l'Hôpital, 67091 Strasbourg Cedex, France.
authors.forename: Pierre-Emmanuel
authors.initials: PE
authors.lastname: Falcoz
keywords: Extracorporeal life support/extracorporeal membrane oxygenation (ECLS/ECMO); ICU; acute respiratory distress syndrome (ARDS); lung transplantation (LTx); thoracic surgery