title: Surveillance of Populations at Risk of Cholangiocarcinoma Development in Rural Communities of Thailand Using the Korat-CCA Verbal Screening Test.
abstract: Cholangiocarcinoma (CCA) is a serious problem in Thailand, particularly in the northeastern region. Active surveillance in rural communities with an appropriat low-cost screening tool is required to facilitate early detection. Therefore, this study aimed to investigate the population at risk of CCA in Bua Yai district, Nakhon Ratchasima province, Northeastern Thailand using the Korat-CCA verbal screening test (KCVST) during June to October 2015. Reliability of KCVST demonstrated a Cronbach alpha coefficient=0.75 Stepwise-multiple regression showed that alcohol consumption was important for CCA screened, followed by agriculture and pesticide use, under-cooked cyprinoid fish consumption, praziquantel use, naïve northeastern people, opisthorchiasis, family relatives with CCA, and cholangitis or cholecystitis or gallstones, respectively. Population at risk for CCA was classified to low risk (63.4%), moderate risk (33.7%), and high risk (1.32%) for CCA. When CCA was screened using ultrasonography, 4 of 32 high risk participants had an abnormal biliary tract with dilated bile ducts. This study indicates that KCVST is a potential useful too which decrease the cost of large scale CCA screening.
authors.affiliation: Parasitic Disease Research Unit, Institute of Medicine, Suranaree University, Nakhon Ratchasima, Thailand E-mail : soraya.k@sut.ac.th.
authors.forename: Soraya J
authors.initials: SJ
authors.lastname: Kaewpitoon
authors.forename: Ratana
authors.initials: R
authors.lastname: Rujirakul
authors.forename: Ryan A
authors.initials: RA
authors.lastname: Loyd
authors.forename: Sukij
authors.initials: S
authors.lastname: Panpimanmas
authors.forename: Likit
authors.initials: L
authors.lastname: Matrakool
authors.forename: Taweesak
authors.initials: T
authors.lastname: Tongtawee
authors.forename: Porntip
authors.initials: P
authors.lastname: Kompor
authors.forename: Jun
authors.initials: J
authors.lastname: Norkaew
authors.forename: Wasugree
authors.initials: W
authors.lastname: Chavengkun
authors.forename: Parichart
authors.initials: P
authors.lastname: Wakkhuwattapong
authors.forename: Jirawoot
authors.initials: J
authors.lastname: Kujapun
authors.forename: Sukanya
authors.initials: S
authors.lastname: Ponphimai
authors.forename: Tanida
authors.initials: T
authors.lastname: Phatisena
authors.forename: Thawatchai
authors.initials: T
authors.lastname: Eaksunti
authors.forename: Poowadol
authors.initials: P
authors.lastname: Polsripradist
authors.forename: Apinya
authors.initials: A
authors.lastname: Joosiri
authors.forename: Inchat
authors.initials: I
authors.lastname: Sukkasam
authors.forename: Natnapa
authors.initials: N
authors.lastname: Padchasuwan
authors.forename: Natthawut
authors.initials: N
authors.lastname: Kaewpitoon
mesh_terms: D000328:Adult; D000818:Animals; D001650:Bile Duct Neoplasms / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D001653:Bile Ducts, Intrahepatic / Q000469:parasitology / Q000473:pathology*; D018281:Cholangiocarcinoma / Q000453:epidemiology / Q000209:etiology* / Q000473:pathology; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D009889:Opisthorchiasis / Q000150:complications* / Q000175:diagnosis / Q000469:parasitology; D009891:Opisthorchis / Q000472:pathogenicity*; D011159:Population Surveillance; D011379:Prognosis; D012307:Risk Factors; D012424:Rural Population; D013785:Thailand / Q000453:epidemiology; D014705:Verbal Behavior