title: Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation.
abstract: BACKGROUND
  Spitz/Reed nevi are melanocytic lesions that may mimic melanoma at clinical, dermatoscopic and histopathological levels. Management strategies of these lesions remain controversial.
  
  
  OBJECTIVE
  We aim a correlation among clinical-dermatoscopic and histological features of a series of Spitz/Reed nevi diagnosed during 7 years at the Department of Dermatology.
  
  
  METHODS
  Clinical, dermatoscopic and histological features of Spitz/Reed nevi diagnosed at our tertiary hospital from 2008 to 2014 were reviewed in order to seek correlation.
  
  
  RESULTS
  All described dermatoscopic patterns for Spitz/Reed nevi were found among the 47 enrolled patients; starburst and atypical/multicomponent patterns prevailed (57.4%). Reticular pattern predominated among children younger than 12 years, whereas homogeneous pattern was more frequent in patients older than 12 years, although these differences were not statistically significant (P=0.785). Among histological atypical lesions, all dermatoscopic patterns were represented, but the atypical/multicomponent predominated (56.3%). Two out of 11 dermatoscopically atypical lesions did not show histopathological counterpart.
  
  
  CONCLUSIONS
  The excision of Spitz/Reed nevi in adults is supported, given the inability to accurately predict those with histopathological atypia, based on clinical and dermatoscopic features, which may raise concern about malignancy.
authors.affiliation: Department of Dermatology and Venereology, Centro Hospitalar São João EPE, Porto, Portugal; Faculty of Medicine, University of Porto, Porto, Portugal.
authors.forename: Ana F
authors.initials: AF
authors.lastname: Pedrosa
authors.affiliation: Faculty of Medicine, University of Porto, Porto, Portugal; Department of Pathology, Centro Hospitalar São João EPE, Porto, Portugal.
authors.forename: Jose M
authors.initials: JM
authors.lastname: Lopes
authors.affiliation: Department of Dermatology and Venereology, Centro Hospitalar São João EPE, Porto, Portugal.
authors.forename: Filomena
authors.initials: F
authors.lastname: Azevedo
authors.affiliation: Department of Dermatology and Venereology, Centro Hospitalar São João EPE, Porto, Portugal; Faculty of Medicine, University of Porto, Porto, Portugal.
authors.forename: Alberto
authors.initials: A
authors.lastname: Mota
keywords: Reed nevus; Spitz nevus; dermatoscopy; spindle and/or epithelioid cell nevus