title: SnapShot: Microglia in Disease.
abstract: The development and maintenance of the central nervous system is dependent upon regulated, homeostatic actions of microglia, which sculpt and refine neuronal circuitry. By contrast, dysregulation of microglia contributes to the pathology of neurodevelopmental disorders such as autism spectrum disorders; neurodegenerative disorders such as Alzheimer's disease; and schizophrenia and chronic neuropathic pain.
authors.affiliation: Program in Neurosciences & Mental Health, Hospital for Sick Children, Toronto ON M5G 1X8, Canada; Developmental Neurosciences Programme, UCL Institute of Child Health, London WC1N 1EH, UK.
authors.forename: Simon
authors.initials: S
authors.lastname: Beggs
authors.affiliation: Program in Neurosciences & Mental Health, Hospital for Sick Children, Toronto ON M5G 1X8, Canada.
authors.forename: Michael W
authors.initials: MW
authors.lastname: Salter
mesh_terms: D000818:Animals; D003071:Cognition; D006801:Humans; D017628:Microglia / Q000378:metabolism*; D009420:Nervous System / Q000166:cytology*; D009422:Nervous System Diseases / Q000378:metabolism / Q000473:pathology* / Q000503:physiopathology