title: SURGICAL TREATMENT OF A MACULAR HOLE IN X-LINKED RETINOSCHISIS.
abstract: OBJECTIVE
  To report a case of full-thickness macular hole in a patient with X-linked retinoschisis and the outcome after surgical repair.
  
  
  METHODS
  A 15-year-old boy with a history of X-linked retinoschisis presented to his ophthalmologist for routine follow-up and was found to have a Stage-3 macular hole in his left eye. His vision was 20/200. The patient underwent pars plana vitrectomy and internal limiting membrane peeling, and he received long-acting gas. Color fundus photography and spectral domain optical coherence tomography (Cirrus; Carl Zeiss Meditech Inc, Dublin, CA) recorded images at office visits, before and after surgical repair.
  
  
  RESULTS
  The initial spectral domain optical coherence tomography of the left eye showed a full-thickness macular hole of 1,370 μm in diameter as well as schisis cavities in the macula. After pars plana vitrectomy and repeat fluid-gas exchange, the hole was closed at the sixth-week follow-up visit. The patient noted a subjective decrease in the size of a central scotoma. Best-corrected visual acuity returned to the baseline of 20/80.
  
  
  CONCLUSIONS
  A large full-thickness macular hole can develop in X-linked retinoschisis, and pars plana vitrectomy with internal limiting membrane peeling may be helpful for successful surgical closure.
authors.affiliation: *Department of Ophthalmology, Edward S. Harkness Eye Institute, Columbia University College of Physicians and Surgeons, New York, New York; and †Vitreous Retina Macular Consultants of New York, New York, New York.
authors.forename: Gregory E
authors.initials: GE
authors.lastname: Stein
authors.forename: Song Eun
authors.initials: SE
authors.lastname: Lee
authors.forename: Royce W S
authors.initials: RWS
authors.lastname: Chen
authors.forename: Lawrence
authors.initials: L
authors.lastname: Yannuzzi
authors.forename: Stanley
authors.initials: S
authors.lastname: Chang
mesh_terms: D000293:Adolescent; D058450:Endotamponade; D005500:Follow-Up Studies; D006801:Humans; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D012167:Retinal Perforations / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D041441:Retinoschisis / Q000150:complications* / Q000175:diagnosis; D041623:Tomography, Optical Coherence; D014792:Visual Acuity; D014821:Vitrectomy / Q000379:methods*