title: [A Case of Acute Arterial Occlusion of the Lower Limb during Chemotherapy for Lung Cancer].
abstract: A 69-year-old man visited a clinic for left leg weakness. With suspicions of lung cancer and a metastatic brain tumor, he was referred to our hospital and was diagnosed with large cell neuroendocrine carcinoma, cT1bN0M1b (BRA), stage IV. After stereotactic radiosurgery for his brain metastasis, he was treated with chemotherapy containing cisplatin and irinotecan. A week after initiating chemotherapy, he suddenly developed severe right leg pain and adynamia. A computed tomography angiogram revealed occlusion of the right common femoral artery, and percutaneous thrombectomy was performed. The symptoms resolved completely, and he was discharged without any sequelae or recurrence. Acute arterial occlusion of the limbs during chemotherapy is uncommon and requires prompt diagnosis and treatment; hence, caution should be paid when it is clinically suspected.
authors.affiliation: Division of Respiratory Medicine, Komaki City Hospital.
authors.forename: Kentaro
authors.initials: K
authors.lastname: Tanaka
authors.forename: Kazuto
authors.initials: K
authors.lastname: Takada
authors.forename: Eiji
authors.initials: E
authors.lastname: Kojima
authors.forename: Takahiro
authors.initials: T
authors.lastname: Shimizu
authors.forename: Shohko
authors.initials: S
authors.lastname: Miyamatsu
authors.forename: Kango
authors.initials: K
authors.lastname: Nohara
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Sakurai
authors.forename: Takaaki
authors.initials: T
authors.lastname: Mizuno
authors.forename: Yuuki
authors.initials: Y
authors.lastname: Yamashita
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use; D001157:Arterial Occlusive Diseases / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D006493:Heparin / Q000627:therapeutic use; D006801:Humans; D035002:Lower Extremity; D008175:Lung Neoplasms / Q000150:complications / Q000188:drug therapy*; D008297:Male; D017131:Thrombectomy; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin; D006493:Heparin