title: Significant advancement of mass spectrometry imaging for food chemistry.
abstract: Food contains various compounds that have an impact on our daily lives. Many technologies have been established to analyze these molecules of interest in foods. However, the analysis of the spatial distribution of these compounds in foods using conventional technology, such as high-performance liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is difficult. Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is considered an ideal complementary approach. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without extraction, purification, separation, or labeling. MALDI-MSI can be used to visualize the spatial distribution of chemical compounds or biomolecules in foods. Although the methodology of MALDI-MSI in food science is not yet fully established, the versatility of MALDI-MSI is expected to open a new frontier in food science. Herein, we describe the principles and applications of MALDI-MSI in food science and related fields.
authors.affiliation: Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja-shi, Okayama 719-1197, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Yoshimura
authors.affiliation: Department of Marine Science and Resources, Nihon University College of Bioresource Sciences, 1866 Kameino, Fujisawa, Kanagawa 252-0880, Japan.
authors.forename: Naoko
authors.initials: N
authors.lastname: Goto-Inoue
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agriculture, Kindai University, 204-3327 Naka-machi, Nara 631-8505, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Moriyama
authors.affiliation: Department of Applied Biological Chemistry, Graduate School of Agriculture, Kindai University, 204-3327 Naka-machi, Nara 631-8505, Japan. Electronic address: zaima@nara.kindai.ac.jp.
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Zaima
mesh_terms: D005504:Food Analysis / Q000295:instrumentation / Q000379:methods*; D005524:Food Technology / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D013058:Mass Spectrometry / Q000295:instrumentation / Q000379:methods*
keywords: Agricultural, forest and fishery products; Food science; Functional food factors; MALDI; MALDI-MSI; Molecular imaging