title: Premature Ejaculation and Erectile Dysfunction in Iranian Prostate Cancer Patients.
abstract: BACKGROUND
  To investigate the prevalence of premature ejaculation (PE) and erectile dysfunction (ED) in a sample of patients with prostate cancer and to determine the utility of the previously suggested cutoffs of the Premature Ejaculation Diagnostic Tool (PEDT) for the diagnosis of PE and that of International Index of Erectile Function (IIEF-5) for ED.
  
  
  METHODS
  A total of 1,202 men with prostate cancer were invited from urology clinics at the universities of Iran, Tehran, Qazvin, Ahvaz, Guilan and Tabriz. Clinical characteristics were collected through medical records. PE and ED diagnoses were made by trained urologists. In addition to the clinical diagnoses, PE and ED were measured through self-report using the PEDT and the IIEF-5. Questionnaire cutoff scores were determined using receiver operating characteristic (ROC) curves and confirmed by predictive ability using logistic regression.
  
  
  RESULTS
  The prevalence of PE was 63.7% and that of ED was 66.2%. Prevalences of PE decreased and that of ED increased with advanced TNM stages. According to ROC, the suggested cutoff for the PEDT to diagnose a PE was ≥ 11 (sensitivity=0.988, 1-specificity=0.084, and predictive ability=0.914) and ≤ 17 for the IIEF-5 (sensitivity=0.966, 1-specificity=0.031, and predictive ability=0.967).
  
  
  CONCLUSIONS
  Prevalence of sexual problems was high in prostate cancer patients in Iran, therefore oncologists should take into account these potential problems when deciding on treatment modalities.
authors.affiliation: Department of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan as Department of Rehabilitation Sciences, Faculty of Health and Social Sciences, The Hong Kong Polytechnic University, Hung Hom, Hong Kong E-mail : Pakpour_Amir@yahoo.com.
authors.forename: Chung-Ying
authors.initials: CY
authors.lastname: Lin
authors.forename: Andrea
authors.initials: A
authors.lastname: Burri
authors.forename: Amir H
authors.initials: AH
authors.lastname: Pakpour
mesh_terms: D000368:Aged; D007172:Erectile Dysfunction / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005500:Follow-Up Studies; D006801:Humans; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D009367:Neoplasm Staging; D061686:Premature Ejaculation / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D015995:Prevalence; D011379:Prognosis; D011471:Prostatic Neoplasms / Q000150:complications* / Q000503:physiopathology; D057566:Self Report; D012725:Sexual Behavior; D011795:Surveys and Questionnaires