title: [HCV infection status and risk factors in remunerated blood donors in Jiangsu province].
abstract: OBJECTIVE
  To investigate the infection status of HCV in remunerated blood donors and risk factors in Jiangsu province.
  
  
  METHODS
  A Cross-sectional study was conducted among people aged >50 years. Questionnaires were used to collect the information about their demographic characteristics and risk behaviors, and venous blood samples were collected from them to detect HCV anti-body, HCV-RNA and other biochemical indicators. EpiData and Stata were used for data entry and statistical analysis.
  
  
  RESULTS
  The overall HCV sero-prevalence rates were 22.55% and 61.05% among remunerated blood donors. Data from multiple stepwise regression analysis showed that alanine aminotransferase(ALT)(adjusted OR=1.38, 95%CI: 1.18-1.62)and aspartate aminotransferase(AST)(adjusted OR=1.30, 95%CI: 1.10-1.54)were associated with the outcomes of HCV infection, and fasting plasma glucose(adjusted OR=1.17, 95%CI: 1.01-1.35)were associated with HCV RNA viral loads.
  
  
  CONCLUSIONS
  The prevalence of HCV infection in remunerated blood donors was high, clinical ALT, AST and fasting plasma glucose levels were associated with the risk for HCV infection and HCV RNA viral load.
authors.affiliation: Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
authors.forename: M Z
authors.initials: MZ
authors.lastname: Chen
authors.affiliation: Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
authors.forename: P
authors.initials: P
authors.lastname: Huang
authors.affiliation: Department of Infectious Diseases, the Jurong People's Hospital, Jurong 212400, China.
authors.forename: H B
authors.initials: HB
authors.lastname: Chen
authors.affiliation: Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
authors.forename: Y N
authors.initials: YN
authors.lastname: Yao
authors.affiliation: Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
authors.forename: Z H
authors.initials: ZH
authors.lastname: Peng
authors.affiliation: Department of Epidemiology, School of Public Health, Nanjing Medical University, Nanjing 211166, China.
authors.forename: R B
authors.initials: RB
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D000410:Alanine Transaminase / Q000097:blood*; D001782:Blood Donors / Q000706:statistics & numerical data*; D002681:China / Q000453:epidemiology; D003430:Cross-Sectional Studies; D005260:Female; D006526:Hepatitis C / Q000097:blood* / Q000175:diagnosis / Q000517:prevention & control / Q000635:transmission; D018937:Hepatitis C Antibodies / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012044:Regression Analysis; D012307:Risk Factors; D016036:Seroepidemiologic Studies; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D018937:Hepatitis C Antibodies; D000410:Alanine Transaminase