title: Psoriasis: Pathogenesis, Assessment, and Therapeutic Update.
abstract: Psoriasis is a chronic condition that affects more than 7 million Americans. This article explores the pathogenesis and physical signs of psoriasis. Over the past 2 decades enhanced understanding of the immunologic basis of psoriasis has led to the development of new systemic agents that have revolutionized the management of this disease, and these modalities, along with traditional therapies, are described.
authors.affiliation: DermDOX Center for Dermatology, 20 North Laurel Street, Hazleton, PA 18201, USA; St. Luke's Health Systems, 801 Ostrum Street, Bethlehem, PA 18015, USA; The Commonwealth Medical College, Scranton, PA 18605, USA; University of Pennsylvania Medical College, Philadelphia, PA 19104, USA. Electronic address: sschleicher@dermdox.org.
authors.forename: Stephen M
authors.initials: SM
authors.lastname: Schleicher
mesh_terms: D002908:Chronic Disease; D006801:Humans; D011565:Psoriasis / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*
keywords: Biologics; Psoriasis; Psoriatic arthritis; Psoriatic comorbidities