title: Sarcomatoid Carcinoma of the Bladder in a Child: Case Report of a Successful Treatment Including Gemcitabine and Cisplatin.
abstract: This report describes an unusual case of sarcomatoid carcinoma of the bladder in a 3-year-old girl. Although saving the patient's life is most essential, it is also essential to consider quality of life. The patient underwent neoadjuvant chemotherapy with gemcitabine and cisplatin for bladder preservation. The tumor considerably decreased in size. After 4 courses of chemotherapy, the patient underwent a partial cystectomy followed by postoperative irradiation with 2 courses of chemotherapy. Seventy months after the operation, she remains alive, showing complete remission with normal bladder function. Chemotherapy resulted in tumor shrinkage and allowed for bladder preservation.
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan. Electronic address: higatakeshi2006@yahoo.co.jp.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Higa
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Oshiro
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Kinjyo
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Yoshihisa
authors.initials: Y
authors.lastname: Miyazato
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Tsukasa
authors.initials: T
authors.lastname: Nakama
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Shirou
authors.initials: S
authors.lastname: Iraha
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Iwao
authors.initials: I
authors.lastname: Nakazato
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Takehiro
authors.initials: T
authors.lastname: Matsuda
authors.affiliation: Department of Hematology and Oncology, Okinawa Prefectural Nanbu Medical Center Children's Medical Center, Haebaru-cho, Arakawa Okinawa, Japan.
authors.forename: Nobuyuki
authors.initials: N
authors.lastname: Hyakuna
authors.affiliation: Department of Diagnostic Pathology, Kochi Red Cross Hospital, Shinhonmachi, Kochi-city Kochi, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Kuroda
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use*; D002277:Carcinoma / Q000473:pathology / Q000628:therapy*; D017024:Chemotherapy, Adjuvant; D002675:Child, Preschool; D002945:Cisplatin / Q000008:administration & dosage; D015653:Cystectomy / Q000379:methods; D003841:Deoxycytidine / Q000008:administration & dosage / Q000031:analogs & derivatives; D005260:Female; D006801:Humans; D020360:Neoadjuvant Therapy; D059351:Organ Sparing Treatments; D018714:Radiotherapy, Adjuvant; D001749:Urinary Bladder Neoplasms / Q000473:pathology / Q000628:therapy*; D000093542:Gemcitabine
chemical_list: D003841:Deoxycytidine; D002945:Cisplatin; D000093542:Gemcitabine