title: Panhypopituitarism due to Absence of the Pituitary Stalk: A Rare Aetiology of Liver Cirrhosis.
abstract: Studies have established a relationship between hypothalamic-pituitary dysfunction and the onset of liver damage, which may occasionally progress to cirrhosis. Patients with hypopituitarism can develop a metabolic syndrome-like phenotype. Insulin resistance is the main pathophysiological axis of metabolic syndrome and is the causal factor in the development of nonalcoholic fatty liver disease (NAFLD). We present the case of a young patient with liver cirrhosis of unknown aetiology that was finally attributed to panhypopituitarism.
authors.affiliation: Internal Department, Hospital de Segovia, Segovia, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Gonzalez Rozas
authors.affiliation: Internal Department, Hospital Universitario Río Hortega, Valladolid, Spain.
authors.forename: Lidia
authors.initials: L
authors.lastname: Hernanz Roman
authors.affiliation: Pathology Department, Hospital Universitario Río Hortega, Valladolid, Spain.
authors.forename: Diego Gonzalez
authors.initials: DG
authors.lastname: Gonzalez
authors.affiliation: Internal Department, Hospital Universitario Río Hortega, Valladolid, Spain.
authors.forename: José Luis
authors.initials: JL
authors.lastname: Pérez-Castrillón