title: Emergency deployment of genetically engineered veterinary vaccines in Europe.
abstract: On the 9th of November 2015, preceding the World Veterinary Vaccine Congress, a workshop was held to discuss how veterinary vaccines can be deployed more rapidly to appropriately respond to future epizootics in Europe. Considering their potential and unprecedented suitability for surge production, the workshop focussed on vaccines based on genetically engineered viruses and replicon particles. The workshop was attended by academics and representatives from leading pharmaceutical companies, regulatory experts, the European Medicines Agency and the European Commission. We here outline the present regulatory pathways for genetically engineered vaccines in Europe and describe the incentive for the organization of the pre-congress workshop. The participants agreed that existing European regulations on the deliberate release of genetically engineered vaccines into the environment should be updated to facilitate quick deployment of these vaccines in emergency situations.
authors.affiliation: Vrije Universiteit Amsterdam, Athena Institute, De Boelelaan 1085, 1081 HV Amsterdam, The Netherlands.
authors.forename: Bahar
authors.initials: B
authors.lastname: Ramezanpour
authors.affiliation: Ceva Santé Animale, 10 avenue de la Ballastière, 33500 Libourne, France.
authors.forename: Jean
authors.initials: J
authors.lastname: de Foucauld
authors.affiliation: Department of Virology, Central Veterinary Institute (CVI-Lelystad), part of Wageningen University and Research Centre, P.O. Box 65, 8200 AB Lelystad, The Netherlands. Electronic address: jeroen.kortekaas@wur.nl.
authors.forename: Jeroen
authors.initials: J
authors.lastname: Kortekaas
mesh_terms: D000818:Animals; D003226:Congresses as Topic; D004196:Disease Outbreaks / Q000662:veterinary; D004630:Emergencies; D005060:Europe; D005818:Genetic Engineering; D033161:Government Regulation; D014611:Vaccination / Q000662:veterinary*; D014612:Vaccines
chemical_list: D014612:Vaccines
keywords: Directive; Europe; Genetically engineered; Live-attenuated; Replicon; Reverse genetics; Vaccine; Virus