title: Expedient synthesis of densely substituted pyrrolo[1,2-a]indoles.
abstract: Cu(OTf)2 catalyzed [6 + 2] cycloaddition reaction of indolyl-2-carbinols with various dienophiles such as indole derived α,β-unsaturated esters, ketones, nitriles and cinnamates is described. The strategy was further applied for the synthesis of optically active pyrrolo[1,2-a]indoles in >97% de using the chiral auxiliary based approach.
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India. ddethe@iitk.ac.in.
authors.forename: Dattatraya H
authors.initials: DH
authors.lastname: Dethe
authors.affiliation: Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur 208016, India. ddethe@iitk.ac.in.
authors.forename: Raghavender
authors.initials: R
authors.lastname: Boda