title: Raison d'etre of Tibial Artery Bypass for Intermittent Claudication in the Era of Endovascular Therapy.
abstract: BACKGROUND
  There is currently no positive opinion regarding infrapopliteal revascularization for intermittent claudication (IC) in any guidelines. The aim of this study was to analyze the outcomes of infragenicular bypass and verify the adequacy of tibial artery bypass for IC.
  
  
  RESULTS
  Over a 21-year period, 58 below-knee popliteal artery (BKPOP) bypasses and 35 tibial artery bypasses were performed for IC caused by arteriosclerosis obliterans. Graft patency and major amputation (MA) were examined as primary endpoints and the predictor of each outcome was estimated by multivariate analysis. The primary patency (PP), secondary patency (SP), and freedom from MA (ffMA) rates of a prosthetic/vein graft in all cases at 5 years were 19/68%, 22/86%, and 78/100% (P<0.01 in all). Limited to vein graft cases, PP and SP rates of popliteal/tibial bypass at 5 years were 73/62% (P=0.32) and 92/80% (P=0.22), respectively. In tibial artery bypass with a vein graft, the PP and SP rates of a single saphenous vein/spliced vein graft at 5 years were 71/46% (P=0.11) and 89/61% (P=0.03). A prosthetic graft was a common negative predictor for graft patency and MA by multivariate analysis.
  
  
  CONCLUSIONS
  Tibial artery bypass is an acceptable treatment option for IC when a single saphenous vein can be harvested as a graft conduit. (Circ J 2016; 80: 1460-1469).
authors.affiliation: Department of Vascular Surgery, Saiseikai General Hospital.
authors.forename: Shinsuke
authors.initials: S
authors.lastname: Mii
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Tanaka
authors.forename: Ryoichi
authors.initials: R
authors.lastname: Kyuragi
authors.forename: Sosei
authors.initials: S
authors.lastname: Kuma
authors.forename: Akio
authors.initials: A
authors.lastname: Kodama
authors.forename: Ryota
authors.initials: R
authors.lastname: Fukunaga
authors.forename: Ichiro
authors.initials: I
authors.lastname: Masaki
authors.forename: Jin
authors.initials: J
authors.lastname: Okazaki
authors.forename: Daihiko
authors.initials: D
authors.lastname: Eguchi
authors.forename: Terutoshi
authors.initials: T
authors.lastname: Yamaoka
authors.forename: Akira
authors.initials: A
authors.lastname: Mori
authors.forename: Atsushi
authors.initials: A
authors.lastname: Guntani
authors.forename: Jun
authors.initials: J
authors.lastname: Okadome
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001807:Blood Vessel Prosthesis; D005260:Female; D006801:Humans; D007383:Intermittent Claudication / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011150:Popliteal Artery / Q000601:surgery; D012189:Retrospective Studies; D012501:Saphenous Vein; D016909:Tibial Arteries / Q000601:surgery*; D014654:Vascular Patency