title: Successful treatment of acute subdural haemorrhage with continuous intravenous infusion of factor VIII in a 17 year old with haemophilia A.
abstract: Intracranial haemorrhage is a common complication of haemophilia, occurring in 2-8% of sufferers [1]. Half of the cases give a history of trauma and despite developments in the management of acute bleeding the condition still carries a mortality of approximately 30% [2]. Surgery may be required, most commonly for evacuation of a subdural haematoma which carries a mortality of up to 40% [3]. We present the case of a 17-year-old haemophiliac with a traumatic subdural haemorrhage, who was treated with a continuous intravenous infusion of factor VIII and made a complete recovery without recourse to surgery. We have found no reference in the world literature of such treatment for acute subdural haemorrhage in a haemophiliac.
authors.affiliation: Department of Surgery, St Peter's Hospital, Guildford Road, Chertsey, Surrey, UKDepartment of Haematology, St Peter's Hospital, Guildford Road, Chertsey, Surrey, UK.
authors.forename: N G
authors.initials: NG
authors.lastname: Richardson
authors.affiliation: Department of Surgery, St Peter's Hospital, Guildford Road, Chertsey, Surrey, UKDepartment of Haematology, St Peter's Hospital, Guildford Road, Chertsey, Surrey, UK.
authors.forename: A L
authors.initials: AL
authors.lastname: Miller
authors.affiliation: Department of Surgery, St Peter's Hospital, Guildford Road, Chertsey, Surrey, UKDepartment of Haematology, St Peter's Hospital, Guildford Road, Chertsey, Surrey, UK.
authors.forename: D F
authors.initials: DF
authors.lastname: O'Shaughnessy
keywords: factor VIII infusion; haemophilia A; subdural haemorrhage