title: Importance of Vehicles in Topical Treatment of Fungal Infections.
abstract: Topical drug therapies are commonly used to manage dermatologic diseases and their manifestations in the skin, hair, nails, and mucous membranes. Compared with systemic treatment, topical drug delivery provides 2 notable benefits in the management of skin diseases. In addition to delivering the active drug, a well-designed vehicle can have supportive effects on the skin, whereas a poorly designed vehicle can have detrimental effects. In many cases, the same active drug is available in several dosage forms, offering the prescriber the ability to tailor treatment to the patient's unique presentation and needs.
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN, USA; Mount Sinai Medical Center, New York, NY, USA; Physicians Skin Care, PLLC, 1169 Eastern Parkway, Suite 2310, Louisville, KY 40217, USA. Electronic address: wedoderm@yahoo.com.
authors.forename: Leon H
authors.initials: LH
authors.lastname: Kircik
mesh_terms: D000287:Administration, Topical; D000935:Antifungal Agents / Q000008:administration & dosage*; D003881:Dermatomycoses / Q000188:drug therapy*; D004304:Dosage Forms; D016503:Drug Delivery Systems; D006801:Humans; D014677:Pharmaceutical Vehicles
chemical_list: D000935:Antifungal Agents; D004304:Dosage Forms; D014677:Pharmaceutical Vehicles
keywords: Adherence; Antifungal; Topical; Vehicle