title: Comparison of severe acute respiratory illness (sari) and clinical pneumonia case definitions for the detection of influenza virus infections among hospitalized patients, western Kenya, 2009-2013.
abstract: Although the severe acute respiratory illness (SARI) case definition is increasingly used for inpatient influenza surveillance, pneumonia is a more familiar term to clinicians and policymakers. We evaluated WHO case definitions for severe acute respiratory illness (SARI) and pneumonia (Integrated Management of Childhood Illnesses (IMCI) for children aged <5 years and Integrated Management of Adolescent and Adult Illnesses (IMAI) for patients aged ≥13 years) for detecting laboratory-confirmed influenza among hospitalized ARI patients. Sensitivities were 84% for SARI and 69% for IMCI pneumonia in children aged <5 years and 60% for SARI and 57% for IMAI pneumonia in patients aged ≥13 years. Clinical pneumonia case definitions may be a useful complement to SARI for inpatient influenza surveillance.
authors.affiliation: Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
authors.forename: Caroline
authors.initials: C
authors.lastname: Makokha
authors.affiliation: Centers for Disease Control and Prevention, Nairobi, Kenya.|Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.
authors.forename: Joshua
authors.initials: J
authors.lastname: Mott
authors.affiliation: Centers for Disease Control and Prevention, Nairobi, Kenya.
authors.forename: Henry N
authors.initials: HN
authors.lastname: Njuguna
authors.affiliation: Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
authors.forename: Sammy
authors.initials: S
authors.lastname: Khagayi
authors.affiliation: Centers for Disease Control and Prevention, Nairobi, Kenya.|Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.
authors.forename: Jennifer R
authors.initials: JR
authors.lastname: Verani
authors.affiliation: Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
authors.forename: Bryan
authors.initials: B
authors.lastname: Nyawanda
authors.affiliation: Kenya Medical Research Institute (KEMRI), Kisumu, Kenya.
authors.forename: Nancy
authors.initials: N
authors.lastname: Otieno
authors.affiliation: Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA.
authors.forename: Mark A
authors.initials: MA
authors.lastname: Katz
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D005260:Female; D006760:Hospitalization; D006801:Humans; D007223:Infant; D007251:Influenza, Human / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D007630:Kenya / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009975:Orthomyxoviridae / Q000235:genetics / Q000302:isolation & purification / Q000502:physiology*; D011014:Pneumonia / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D012141:Respiratory Tract Infections / Q000453:epidemiology / Q000628:therapy / Q000821:virology*; D018571:Sentinel Surveillance; D055815:Young Adult