title: Spatial distribution of electrical reconnection after pulmonary vein isolation in patients with recurrent paroxysmal atrial fibrillation.
abstract: BACKGROUND
  Recurrence of atrial fibrillation after pulmonary vein isolation (PVI) occurs frequently and may be associated with electrical reconnection of the pulmonary veins (PV). We investigated spatial distribution of electrical reconnection during re-do procedures in patients with paroxysmal atrial fibrillation who had previous successful acute electrical PVI with either single irrigated tip, antral ablation (s-RF; n = 38) or multi-electrode, duty-cycled ablation (PVAC; n = 48).
  
  
  RESULTS
  EP navigator, mapping and irrigated tip ablation catheters were used in all re-do procedures. Sites of reconnection were assessed in a 12-segment model. Baseline clinical and demographic characteristics were similar in both groups. The number of PVs reconnected per patient was similar in both groups (2.9 ± 0.9 and 3.2 ± 0.7 (p = 0.193), s‑RF and PVAC, respectively), and each PV was equally affected. However, the inferior quadrant of the right lower PV was significantly more vulnerable to reconnection after previous PVAC ablation, whereas the superior quadrant of the right upper PV showed significantly more reconnection in the s‑RF group.
  
  
  CONCLUSIONS
  The overall number of PVs reconnected was equally high in both groups, and each PV was affected equally. However, there were significant differences in the spatial distribution of electrical reconnection. Better understanding of predilection sites for reconnection might help to improve the long-term success rate of PVI.
authors.affiliation: Department of Cardiology, Catharina hospital, Eindhoven, The Netherlands. nard.rademakers@catharinaziekenhuis.nl.
authors.forename: L M
authors.initials: LM
authors.lastname: Rademakers
authors.affiliation: Philips Healthcare, Best, The Netherlands.
authors.forename: I
authors.initials: I
authors.lastname: Romero
authors.affiliation: Department of Cardiology, Catharina hospital, Eindhoven, The Netherlands.
authors.forename: T A
authors.initials: TA
authors.lastname: Simmers
authors.affiliation: Department of Cardiology, Catharina hospital, Eindhoven, The Netherlands.
authors.forename: P H
authors.initials: PH
authors.lastname: van der Voort
authors.affiliation: Department of Cardiology, Catharina hospital, Eindhoven, The Netherlands.
authors.forename: A M
authors.initials: AM
authors.lastname: Meijer
authors.affiliation: Department of Cardiology, Catharina hospital, Eindhoven, The Netherlands.
authors.forename: L R
authors.initials: LR
authors.lastname: Dekker
keywords: Atrial fibrillation; Pulmonary vein isolation; Reconnection