title: Keratocystic odontogenic tumors related to Gorlin-Goltz syndrome: A clinicopathological study.
abstract: BACKGROUND
  Assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with Gorlin-Goltz syndrome in our institution from 2004 to 2015.
  
  
  METHODS
  After histopathological analyses of KCOT related to Gorlin-Goltz syndrome, 7 patients were assessed. These patients presented a total of 15 primary and 2 recurrent KCOT.
  
  
  RESULTS
  All patients presented a multiple KCOT, and 13 lesions were located in mandible (77%) and 4 (23%) in maxilla. Most of the tumors presented a unilocular pattern (71%) and had tooth association (88%). Four patients (57%) were in the age group of 10-19 years and three patients (43%) were in the age group of 20-29 years. There were four male and three female patients.
  
  
  CONCLUSIONS
  KCOT is a frequent manifestation of Gorlin-Goltz syndrome and can be its first sign, mainly in young patients. The four patients presented with two lesions (57%) and three lesions in three patients (43%).
authors.affiliation: Post Graduate Scholar, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Srinagar, India.
authors.forename: Mohammed Israr Ul
authors.initials: MI
authors.lastname: Khaliq
authors.affiliation: Professor and Head, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Srinagar, India.
authors.forename: Ajaz A
authors.initials: AA
authors.lastname: Shah
authors.affiliation: Associate Professor, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Srinagar, India.
authors.forename: Irshad
authors.initials: I
authors.lastname: Ahmad
authors.affiliation: Associate Professor, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Srinagar, India.
authors.forename: Shahid
authors.initials: S
authors.lastname: Hasan
authors.affiliation: Assistant Professor, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Aurangabad, India.
authors.forename: Sagar S
authors.initials: SS
authors.lastname: Jangam
authors.affiliation: Junior Resident, Department of Oral and Maxillofacial Surgery, Govt. Dental College & Hospital, Srinagar, India.
authors.lastname: Farah
authors.affiliation: Junior Resident, Department of Chest Medicine, SKIMS MC, Srinagar, India.
authors.lastname: Anwar
keywords: Gorlin–Goltz syndrome; Keratocyst; Keratocystic odontogenic tumor; Nevoid basal cell carcinoma syndrome