title: Benign metastasizing leiomyomas in the lungs: a case study.
abstract: Benign metastasizing leiomyoma (BML) is a rare disease that occurs in middle-aged women with a history of uterine myomas. The most common location of BML is the lungs. We report the case of a 44-year-old obese woman (BMI 45.5) who underwent surgery to remove uterine leiomyomata and then continued to take a drug containing the hormone estradiol for a period of 15 years. Computed tomography chest examinations revealed multiple size nodules of varying size in both lungs. Videothoracoscopy and right thoracotomy was performed, and a few nodules were enucleated from each lobe of the right lung. Postoperative histopathological examination revealed benign metastasizing leiomyoma staining positive for estrogen and progesterone receptors (ER+, PR+). Because of the hormonally dependent cell proliferation, the previously used hormonal drug was discontinued. Treatment with a gonadotropin-releasing hormone analog was included, yielding radiological stabilization of the lung lesions.
authors.affiliation: Center of Pulmonology and Thoracic Surgery, Bystra, Poland.
authors.forename: Alina Janina
authors.initials: AJ
authors.lastname: Wiencek-Weiss
authors.affiliation: Center of Pulmonology and Thoracic Surgery, Bystra, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Bruliński
keywords: BML; benign metastasizing leiomyoma; uterine myomas