title: Muscle histology changes after short term vibration training in healthy controls.
abstract: In search for additional counter measures of muscle atrophy vibration exercise training may have substantial effort for patients with neuromuscular disorders. To cover safety aspects and obtain muscle morphology data, a pilot study was performed in eleven healthy men. Countermovement jump, squat jump, drop jump and one repetition maximum test (1RM) were performed on a force platform before and after a 6 week training period. No severe side effects were found. Repeated needle muscle biopsies of the vastus lateralis muscle revealed a selective pre- to post-training type-2 myofiber hypertrophy of up to 50 %. The hypertrophy factors were 160 and 310, for type-2 myofibers. The mechanography system showed a significant increase in the 1RM maximum weight lifted (pre: 111,8 kg ± 11,5; post: 140,9 kg ± 13,00; p < 0,001). Vibration exercise is a safe and effective technique which desires further approval as counter measure in different types of neuromuscular atrophy.
authors.affiliation: Friedrich-Baur-Institute, Department of Neurology, Klinikum der Universität München, Germany.
authors.forename: Benedikt
authors.initials: B
authors.lastname: Schoser
mesh_terms: D000328:Adult; D001706:Biopsy; D064368:Healthy Volunteers; D006801:Humans; D006984:Hypertrophy; D008297:Male; D018482:Muscle, Skeletal / Q000502:physiology*; D010865:Pilot Projects; D014732:Vibration / Q000627:therapeutic use*
keywords: muscle atrophy; muscle biopsy; muscle morphometry; vibration exercise