title: Long-term Survival From Muscleinvasive Bladder Cancer With Initial Presentation of Symptomatic Cerebellar Lesion: The Role of Selective Surgical Extirpation of the Primary and Metastatic Lesion.
abstract: A 59-year-old man was diagnosed with urothelial carcinoma involving an isolated cerebellar metastasis after presenting to the emergency department for headache complaints. After selective surgical excision of the symptomatic brain lesion and delayed cystectomy due to intractable hematuria, he survived 11 years without evidence of recurrence or subsequent systemic chemotherapy. He eventually expired after delayed recurrence in the lung, supraclavicular lymph node, and brain. To our knowledge, this is the only case of prolonged survival from urothelial carcinoma after selective surgical extirpation of the primary and metastatic lesion without subsequent systemic chemotherapy.
authors.affiliation: Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Ganesh K
authors.initials: GK
authors.lastname: Kartha
authors.affiliation: Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Joseph
authors.initials: J
authors.lastname: Sanfrancesco
authors.affiliation: Imaging Institute, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Esther
authors.initials: E
authors.lastname: Udoji
authors.affiliation: Case Western Reserve University School of Medicine, Cleveland, OH.
authors.forename: Hemant
authors.initials: H
authors.lastname: Chaparala
authors.affiliation: Department of Pathology, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: Donna
authors.initials: D
authors.lastname: Hansel
authors.affiliation: Glickman Urological & Kidney Institute, Cleveland Clinic Foundation, Cleveland, OH.
authors.forename: J Stephen
authors.initials: JS
authors.lastname: Jones
keywords: Bladder cancer; Cystectomy; Metastasis; Urothelial carcinoma