title: Corneal Thickness Profile Changes After Femtosecond LASIK for Hyperopia.
abstract: OBJECTIVE
  To compare changes in the corneal thickness profile before and 6 months after femtosecond laser in situ keratomileusis (LASIK) for hyperopia.
  
  
  METHODS
  In a prospective noncomparative case series study, 24 eyes of 20 hyperopic patients undergoing femtosecond LASIK were examined preoperatively and 6 months postoperatively. Corneal profile was measured using Pentacam HR device. Paired t test was used to compare preoperative and postoperative values. Spearman correlation analysis was performed to evaluate the relationship between the central corneal thickness changes and attempted spherical equivalent refraction (SER).
  
  
  RESULTS
  The mean uncorrected distance visual acuity significantly improved after surgery (P<0.001). Significant differences in central, midperipheral, ablative annular, and peripheral corneal thicknesses were observed from preoperatively to 6 months postoperatively (all P<0.001). There was no significant correlation between the changes in the central corneal thickness and attempted SER (P=0.23).
  
  
  CONCLUSIONS
  The corneal thicknesses across the whole ablation zone including central corneal thickness, significantly decrease postoperatively compared with preoperatively.
authors.affiliation: Department of Ophthalmology (T.L., X.D.Z.), Jinshan Hospital of Fudan University, Shanghai, China; and Department of Ophthalmology (Z.C., X.T.Z.), Eye and ENT Hospital of Fudan University, Shanghai, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Zhou
authors.forename: Zhi
authors.initials: Z
authors.lastname: Chen
authors.forename: Xingtao
authors.initials: X
authors.lastname: Zhou
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D003315:Cornea / Q000473:pathology*; D063171:Corneal Pachymetry; D019781:Corneal Topography; D006801:Humans; D006956:Hyperopia / Q000503:physiopathology / Q000601:surgery*; D020731:Keratomileusis, Laser In Situ / Q000379:methods*; D054018:Lasers, Excimer / Q000627:therapeutic use*; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D014792:Visual Acuity / Q000502:physiology