title: Palladium-Catalyzed Highly Chemoselective Intramolecular C-H Aminocarbonylation of Phenethylamines to Six-Membered Benzolactams.
abstract: A palladium-catalyzed highly selective intramolecular C-H aminocarbonylation of Br-functionalized phenethylamines in the presence of CO was achieved while leaving the C-Br bond unreacted to afford six-membered benzolactams with good to high yields. The remaining C-Br group in the cyclized product was successfully used as a reactive center for further functionalization through various palladium-catalyzed coupling reactions.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University , 6-3, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Taneda
authors.affiliation: School of Pharmacy and Pharmaceutical Sciences, Mukogawa Women's University , 11-68, 9-Bancho, Koshien, Nishinomiya, Hyogo 663-8179, Japan.
authors.forename: Kiyofumi
authors.initials: K
authors.lastname: Inamoto
authors.affiliation: Graduate School of Pharmaceutical Sciences, Tohoku University , 6-3, Aoba, Aramaki, Aoba-ku, Sendai 980-8578, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Kondo