title: Urachal Carcinoma with Choroidal, Lung, Lymph Node, Adrenal, Mammary, and Bone Metastases and Peritoneal Carcinomatosis Showing Partial Response after Chemotherapy Treatment with a Modified Docetaxel, Cisplatin and 5-Fluorouracil Regimen.
abstract: Urachal carcinoma (UC) is a rare tumor mainly affecting middle-aged males. Metastases occur most frequently in lymph nodes and the lungs. There are no standard adjuvant and metastatic treatments. We report the case of a 36-year-old female with UC treated with partial cystectomy who relapsed 3 years after surgery with left choroidal, lung, mediastinal lymph node, right adrenal, mammary, and bone metastases as well as peritoneal carcinomatosis. She obtained a partial response after 10 cycles of chemotherapy with a modified docetaxel, cisplatin and 5-fluorouracil (mTPF) regimen. This is the first report on the use of the mTPF regimen in UC and on the existence of choroidal, adrenal, and mammary metastases.
authors.affiliation: Centre Léon Bérard, Macon, France.
authors.forename: Kathleen
authors.initials: K
authors.lastname: Dekeister
authors.affiliation: Polyclinique du Val de Saône, Macon, France.
authors.forename: Jean Louis
authors.initials: JL
authors.lastname: Viguier
authors.affiliation: Hôpital Edouard Herriot, Macon, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Martin
authors.affiliation: Hôpital de la Croix-Rousse, Lyon, France.
authors.forename: Anh Minh
authors.initials: AM
authors.lastname: Nguyen
authors.affiliation: Centre Léon Bérard, Macon, France.
authors.forename: Helen
authors.initials: H
authors.lastname: Boyle
authors.affiliation: Centre Léon Bérard, Macon, France.
authors.forename: Aude
authors.initials: A
authors.lastname: Flechon
keywords: Choroidal, adrenal, and mammary metastases; Modified docetaxel, cisplatin and 5-fluorouracil regimen; Urachal carcinoma