title: Mechanical properties and biocompatibility of co-axially electrospun polyvinyl alcohol/maghemite.
abstract: Electrospinning is a simple and efficient process in producing nanofibers. To fabricate nanofibers made of a blend of two constituent materials, co-axial electrospinning method is an option. In this method, the constituent materials contained in separate barrels are simultaneously injected using two syringe nozzles arranged co-axially and the materials mix during the spraying process forming core and shell of the nanofibers. In this study, co-axial electrospinning method is used to fabricate nanofibers made of polyvinyl alcohol and maghemite (γ-Fe2O3). The concentration of polyvinyl alcohol and amount of maghemite nanoparticle loading were varied, at 5 and 10 w/v% and at 1-10 v/v%, respectively. The mechanical properties (strength and Young's modulus), porosity, and biocompatibility properties (contact angle and cell viability) of the electrospun mats were evaluated, with the same mats fabricated by regular single-nozzle electrospinning method as the control. The co-axial electrospinning method is able to fabricate the expected polyvinyl alcohol/maghemite nanofiber mats. It was noticed that the polyvinyl alcohol/maghemite electrospun mats have lower mechanical properties (i.e. strength and stiffness) and porosity, more hydrophilicity (i.e. lower contact angle), and similar cell viability compared to the mats fabricated by single-nozzle electrospinning method.
authors.affiliation: Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Skudai, Malaysia.
authors.forename: Nor Hasrul Akhmal
authors.initials: NH
authors.lastname: Ngadiman
authors.affiliation: Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Skudai, Malaysia.
authors.forename: Noordin
authors.initials: N
authors.lastname: Mohd Yusof
authors.affiliation: Faculty of Chemical Engineering, Universiti Teknologi Malaysia, Skudai, Malaysia.
authors.forename: Ani
authors.initials: A
authors.lastname: Idris
authors.affiliation: Faculty of Mechanical Engineering, Universiti Teknologi Malaysia, Skudai, Malaysia Department of Mechanical, Robotics, and Energy Engineering, Dongguk University, Seoul, Korea noordin@fkm.utm.my.
authors.forename: Denni
authors.initials: D
authors.lastname: Kurniawan
mesh_terms: D001672:Biocompatible Materials / Q000138:chemical synthesis / Q000737:chemistry*; D001696:Biomechanical Phenomena; D002460:Cell Line; D002470:Cell Survival; D005290:Ferric Compounds / Q000737:chemistry*; D006801:Humans; D008422:Materials Testing; D057139:Nanofibers / Q000737:chemistry / Q000648:ultrastructure; D036103:Nanotechnology / Q000295:instrumentation; D011142:Polyvinyl Alcohol / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D005290:Ferric Compounds; C000499:ferric oxide; D011142:Polyvinyl Alcohol
keywords: Electrospinning; biocompatibility; co-axial; maghemite; nanofiber; polyvinyl alcohol; properties