title: Bariatric Surgery: A Potential Treatment for Type 2 Diabetes in Youth.
abstract: Type 2 diabetes, once referred to as "adult-onset" diabetes, has now emerged as a formidable threat to the health of obese adolescents. Although there is growing evidence regarding the epidemiology of type 2 diabetes in youth and its multisystem health consequences, treatment options have lagged and progression of disease occurs even with aggressive medical therapy. Increasing interest in the application of bariatric surgery for adolescents with type 2 diabetes has evolved in part because of the evidence demonstrating improvement or remission in many adults with diabetes after surgery. Here, we review the burden of type 2 diabetes in youth including its associated complications, discuss the outcomes and complications of bariatric surgery in adolescents with diabetes, and conclude with recommendations for future research and options for refinement of the use of bariatric surgery in this patient population.
authors.affiliation: Department of Pediatrics, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH.
authors.forename: Amy S
authors.initials: AS
authors.lastname: Shah
authors.affiliation: Division of Endocrinology, Metabolism, and Nutrition, Department of Medicine, Duke University School of Medicine, Durham, NC Durham VA Medical Center, Durham, NC.
authors.forename: David
authors.initials: D
authors.lastname: D'Alessio
authors.affiliation: Department of Child Health, King's College Hospital and King's College London GKT School of Medical Education, London, U.K.
authors.forename: Martha E
authors.initials: ME
authors.lastname: Ford-Adams
authors.affiliation: Department of Pediatric Surgery, King's College Hospital and King's College London GKT School of Medical Education, London, U.K.
authors.forename: Ashish P
authors.initials: AP
authors.lastname: Desai
authors.affiliation: Department of Surgery, Cincinnati Children's Hospital and University of Cincinnati, Cincinnati, OH thomas.inge@cchmc.org.
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Inge
mesh_terms: D000293:Adolescent; D000328:Adult; D017668:Age of Onset; D050110:Bariatric Surgery / Q000379:methods / Q000706:statistics & numerical data; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000453:epidemiology / Q000601:surgery*; D006801:Humans; D063766:Pediatric Obesity / Q000150:complications / Q000453:epidemiology / Q000601:surgery; D012074:Remission Induction