title: Canine and Human Atopic Dermatitis: Two Faces of the Same Host-Microbe Interaction.
abstract: Host-microbe interaction has been suggested to play a critical role in the pathogenesis of atopic dermatitis. The dog has been shown to be the best model to study both pathogenesis and microbiome modifications in atopic dermatitis. Bradley et al. show a significant correlation between microbiome diversity, clinical signs, and skin barrier function in atopic dogs before, during, and after antimicrobial therapy.
authors.affiliation: Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, USA. Electronic address: dsantoro@ufl.edu.
authors.forename: Domenico
authors.initials: D
authors.lastname: Santoro
authors.affiliation: Department of Veterinary Pathobiology, Dermatopathology Specialty Service, College of Veterinary Medicine & Biomedical Sciences, Texas A&M University, College Station, Texas, USA.
authors.forename: Aline
authors.initials: A
authors.lastname: Rodrigues Hoffmann
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001707:Biopsy, Needle; D003876:Dermatitis, Atopic / Q000188:drug therapy / Q000382:microbiology* / Q000473:pathology*; D004195:Disease Models, Animal; D004283:Dog Diseases / Q000382:microbiology / Q000473:pathology; D004285:Dogs; D006801:Humans; D007150:Immunohistochemistry; D064307:Microbiota; D013045:Species Specificity; D013210:Staphylococcus / Q000472:pathogenicity*
chemical_list: D000900:Anti-Bacterial Agents