title: Defining cognitive-behavior therapy response and remission in pediatric OCD: a signal detection analysis of the Children's Yale-Brown Obsessive Compulsive Scale.
abstract: The objective of the study was to examine the optimal Children's Yale-Brown Obsessive-Compulsive Scale (CY-BOCS) percent reduction and raw cutoffs for predicting cognitive-behavioral treatment (CBT) response among children and adolescents with obsessive-compulsive disorder (OCD). The sample consisted of children and adolescents with OCD (N = 241) participating in the first step of the Nordic long-term OCD treatment study and receiving 14 weekly sessions of CBT in the form of exposure and response prevention. Evaluations were conducted pre- and post-treatment, included the CY-BOCS, Clinical Global Impressions-severity/improvement. The results showed that the most efficient CY-BOCS cutoffs were 35 % reduction for treatment response, 55 % reduction for remission, and a post-treatment CY-BOCS raw total score of 11 for treatment remission. Overall, our results diverge from previous research on pediatric OCD with more conservative cutoffs (higher cutoff reduction for response and remission, and lower raw score for remission). Further research on optimal cutoffs is needed.
authors.affiliation: Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Nydalen, Postbox 4623, 0405, Oslo, Norway. gudmundur.skarphedinsson@r-bup.no.
authors.forename: Gudmundur
authors.identifier: http://orcid.org/0000-0002-8618-153X
authors.initials: G
authors.lastname: Skarphedinsson
authors.affiliation: Department of Pediatrics, Psychology and Psychiatry, University of South Florida, St. Petersburg, FL, USA.
authors.forename: Alessandro S
authors.initials: AS
authors.lastname: De Nadai
authors.affiliation: Department of Pediatrics, Psychology and Psychiatry, University of South Florida, St. Petersburg, FL, USA.|Department of Health Policy and Management, University of South Florida, Tampa, FL, USA.|Rogers Behavioral Health-Tampa Bay, Tampa, FL, USA.|All Children's Hospital, Johns Hopkins Medicine, St. Petersburg, FL, USA.
authors.forename: Eric A
authors.initials: EA
authors.lastname: Storch
authors.affiliation: Department of Pediatrics, Psychology and Psychiatry, University of South Florida, St. Petersburg, FL, USA.
authors.forename: Adam B
authors.initials: AB
authors.lastname: Lewin
authors.affiliation: Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Nydalen, Postbox 4623, 0405, Oslo, Norway.
authors.forename: Tord
authors.initials: T
authors.lastname: Ivarsson
mesh_terms: D000293:Adolescent; D002648:Child; D015928:Cognitive Behavioral Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D009771:Obsessive-Compulsive Disorder / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy*; D012074:Remission Induction; D017603:Signal Detection, Psychological; D016896:Treatment Outcome
keywords: Children’s Yale-Brown Obsessive–Compulsive Scale; Cognitive-behavioral treatment; Obsessive–compulsive disorder; Treatment