title: Synthesis, crystal structure and spectroscopic studies of bismuth(III) complex with 2-substituted benzimidazole ligands.
abstract: Reaction of BiCl3 with 2-(2-hydroxy-3-methoxyphenyl)benzimidazole (HL) in tetrahydrofuran (THF) under reflux gave mononuclear complex of formula [Bi(HL)2Cl3·H2O]. The binding interaction of the complex with bovine serum albumin (BSA) was investigated using the fluorescence quenching method. The experimental results showed that the complex could bind to BSA in the proportion of about 1:1. The binding reaction was spontaneous and hydrophobic force played major role in the reaction. The binding of the complex to BSA could change the microenvironment and conformation of BSA.
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Chuan-Hua
authors.initials: CH
authors.lastname: Li
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Xu
authors.initials: X
authors.lastname: Tao
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Jian-Hong
authors.initials: JH
authors.lastname: Jiang
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Xu
authors.initials: X
authors.lastname: Li
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Sheng-Xiong
authors.initials: SX
authors.lastname: Xiao
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Li-Ming
authors.initials: LM
authors.lastname: Tao
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Ju-Feng
authors.initials: JF
authors.lastname: Zhou
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Ming-An
authors.initials: MA
authors.lastname: Xie
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Zi
authors.initials: Z
authors.lastname: Xia
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Si-Min
authors.initials: SM
authors.lastname: Tang
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China.
authors.forename: Han-Meng
authors.initials: HM
authors.lastname: Yuan
authors.affiliation: Hunan Provincial Key Laboratory of Xiangnan Rare-Precious Metals Compounds and Applications, Department of Chemistry and Life Science, Xiangnan University, Chenzhou 423000, Hunan, PR China. Electronic address: liqiangguo@163.com.
authors.forename: Qiang-Guo
authors.initials: QG
authors.lastname: Li
mesh_terms: D000818:Animals; D001562:Benzimidazoles / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D001729:Bismuth / Q000737:chemistry* / Q000378:metabolism; D002417:Cattle; D056831:Coordination Complexes / Q000138:chemical synthesis / Q000737:chemistry* / Q000378:metabolism; D018360:Crystallography, X-Ray; D057927:Hydrophobic and Hydrophilic Interactions; D008024:Ligands; D008958:Models, Molecular; D011485:Protein Binding; D012710:Serum Albumin, Bovine / Q000737:chemistry / Q000378:metabolism; D013050:Spectrometry, Fluorescence; D013816:Thermodynamics
chemical_list: D001562:Benzimidazoles; D056831:Coordination Complexes; D008024:Ligands; D012710:Serum Albumin, Bovine; D001729:Bismuth
keywords: Benzimidazole; Bismuth(III) complex; Bovine serum albumin; Thermodynamic parameters