title: [Progression of Cryptogenic Iron Deficiency Anemia and Efficacy of Low-dose Prednisolone in a Rheumatic Case].
abstract: Iron deficiency anemia (IDA) in rheumatic patients result from gastrointestinal bleeding owing usually tonon-steroidal anti-inflammatory agent. We experienced a rheumatic female patient in whom cryptogenic IDA deteriorated to 6.9 g x dl(-1) of hemoglobin (Hb) and 4 μg x dl(-1) of serum iron after surgery of femoral neck fracture. Considering the ascent of inflammatory reaction, we administered 5 mg per day of prednisolone(PSL) to her. In two month, IDA improved to 10.3 g x dl(-1)of Hb and 45 μg x dl(-1)of serum iron. In conclusion, cryptogenic IDA can deteriorate under 7.0 g x dl(-1)of Hb in rheumatic patients, and the administration of low-dose prednisolone may be effective because of the improved absorbtion of iron and appetite. Anemic condition in rheumatic case needs to be given attention to because of the possibility of its progression without noticing.
authors.forename: Satoshi
authors.initials: S
authors.lastname: Yamaguchi
mesh_terms: D000368:Aged; D018798:Anemia, Iron-Deficiency / Q000188:drug therapy* / Q000209:etiology; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use*; D012216:Rheumatic Diseases / Q000150:complications*
chemical_list: D011239:Prednisolone