title: Improvement in Serum Anti-Müllerian Hormone Levels in Infertile Patients after Hyperbaric Oxygen (preliminary results).
abstract: OBJECTIVE
  To assess whether hyperbaric oxygen sessions elevate serum levels of anti-Müllerian hormone (AMH) in patients diagnosed with infertility with serum levels of less than or equal to 1 ng/dl AMH.
  
  
  METHODS
  A study was performed on 4 patients diagnosed with infertility. Serum AMH level was measured at the beginning and end of hyperbaric oxygen sessions, and endometrial thickness was measured on endometrial cycle day 14 before and during the hyperbaric oxygen sessions.
  
  
  RESULTS
  In two of the four patients, the serum AMH level increased by 40% and 116%. In one patient the serum AMH level was not elevated, with a serum AMH level before and after treatment of 0.1 ng/dl. The fourth patient became pregnant during the hyperbaric oxygen sessions. Endometrial thickness was not improved in any of our patients.
  
  
  CONCLUSIONS
  This study showed that hyperbaric oxygen sessions can increase serum AMH levels, with a significant increase of 116% in one case. Therefore, this therapy can be used as an alternative treatment for patients with serum AMH levels of less than or equal to 1 ng/dl and a limited number of eggs for IVF cycles but not for patients with serum AMH levels of less than or equal to 0.1 ng/dl, as we did not observe an increase in serum AMH level in patients with an initial AMH level of 0.1 ng/dl. This study did not demonstrate improvement in endometrial growth following hyperbaric oxygen sessions.
authors.affiliation: HISPAREP Fertility Clinic, Hospital Español, México DF.
authors.forename: Jesus Fernando Gallardo
authors.initials: JF
authors.lastname: Pineda
authors.affiliation: HISPAREP Fertility Clinic, Hospital Español, México DF.
authors.forename: Carlos Gerardo Salazar López
authors.initials: CG
authors.lastname: Ortiz
authors.affiliation: HISPAREP Fertility Clinic, Hospital Español, México DF.
authors.forename: Gonzalo de Jesus Siu
authors.initials: Gde J
authors.lastname: Moguel
authors.affiliation: Multidisciplinary Diabetes Center México City (Hyperbaric Chamber).
authors.forename: Carlos Roberto Eduardo Castro
authors.initials: CR
authors.lastname: Lopez
authors.affiliation: HISPAREP Fertility Clinic, Hospital Español, México DF.
authors.forename: Héctor Mondragón
authors.initials: HM
authors.lastname: Alcocer
authors.affiliation: HISPAREP Fertility Clinic, Hospital Español, México DF.
authors.forename: Sergio Téllez
authors.initials: ST
authors.lastname: Velasco
keywords: Anti-Mullerian Hormone; Hyperbaric Chamber; Low Ovarian Reserve