title: Osteonecrosis of the femoral head in haemophiliacs: not all joint disease is haemophilic arthropathy.
abstract: Osteonecrosis (ON) is rare while arthropathy is common in persons with haemophilia. A recent case of bilateral ON of the femoral head prompted us to review our experience with hip arthroplasty. We identified nine patients with presumed end-stage haemophilic arthropathy. Four of the nine individuals had radiographic findings suggestive of ON, but without unequivocal microscopic evidence of ON. It is important to recognize ON at an early stage because there are surgical interventions which may prolong the life of the joint and improve quality of life. We suggest that ON should be included in the differential diagnosis of hip pathology in persons with haemophilia presenting with hip pain or dysfunction.
authors.affiliation: College of Medicine, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA,Department of Pathology, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA,Department of Orthopaedics, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA.
authors.forename: C E
authors.initials: CE
authors.lastname: Dye
authors.affiliation: College of Medicine, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA,Department of Pathology, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA,Department of Orthopaedics, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA.
authors.forename: E E
authors.initials: EE
authors.lastname: Frauenhoffer
authors.affiliation: College of Medicine, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA,Department of Pathology, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA,Department of Orthopaedics, The Pennsylvania State University, The Milton S. Hershey Medical Center, PO Box 850, Hershey, PA 17033, USA.
authors.forename: M
authors.initials: M
authors.lastname: Vrahas
keywords: HIV; haemophilia; haemophilic arthropathy; osteonecrosis; zidovudine.