title: Dietary vitamin C reduced mercury contents in the tissues of juvenile olive flounder (Paralichthys olivaceus) exposed with and without mercury.
abstract: A 2×3 factorial design was employed to evaluate the effects of dietary vitamin C (l-ascorblyl-2-monophosphate, C2MP) levels on growth and tissue mercury (Hg) accumulations in juvenile olive flounder, Paralichthys olivaceus. Six experimental diets with two levels of mercuric chloride (0 or 20mg HgCl2/kg diet) and three levels of vitamin C (0, 100, or 200mg C2MP/kg diet) were added to the basal diet. At the end of 6 weeks feeding trial, in presence or absence of dietary Hg, fish body weight gain, specific growth rate, feed efficiency, protein efficiency ratio and whole body lipid content were increased in a dose-dependent manner as dietary vitamin C level increased in the diets. Interestingly, fish fed 100 or 200mg C2MP/kg diets showed significant interactive effects on reducing Hg content in kidney tissue. These results revealed that dietary vitamin C as 100 or 200mg C2MP/kg diet had protective effect against Hg accumulation in juvenile olive flounder.
authors.affiliation: Department of Marine Bio-materials and Aquaculture/Feeds & Foods Nutrition Research Center (FFNRC), Pukyong National University, Busan 608-737, Rep. of Korea.
authors.forename: Jun-Ho
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Marine Bio-materials and Aquaculture/Feeds & Foods Nutrition Research Center (FFNRC), Pukyong National University, Busan 608-737, Rep. of Korea.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Moniruzzaman
authors.affiliation: Department of Marine Bio-materials and Aquaculture/Feeds & Foods Nutrition Research Center (FFNRC), Pukyong National University, Busan 608-737, Rep. of Korea.
authors.forename: Hyeonho
authors.initials: H
authors.lastname: Yun
authors.affiliation: Department of Marine Bio-materials and Aquaculture/Feeds & Foods Nutrition Research Center (FFNRC), Pukyong National University, Busan 608-737, Rep. of Korea.
authors.forename: Seunghan
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Marine Bio-materials and Aquaculture/Feeds & Foods Nutrition Research Center (FFNRC), Pukyong National University, Busan 608-737, Rep. of Korea.
authors.forename: Youngjin
authors.initials: Y
authors.lastname: Park
authors.affiliation: Department of Marine Bio-materials and Aquaculture/Feeds & Foods Nutrition Research Center (FFNRC), Pukyong National University, Busan 608-737, Rep. of Korea. Electronic address: scbai@pknu.ac.kr.
authors.forename: Sungchul C
authors.initials: SC
authors.lastname: Bai
mesh_terms: D000818:Animals; D001205:Ascorbic Acid / Q000493:pharmacokinetics / Q000494:pharmacology*; D004032:Diet; D029941:Fish Proteins / Q000378:metabolism; D005432:Flounder / Q000254:growth & development / Q000378:metabolism; D007668:Kidney / Q000378:metabolism; D050356:Lipid Metabolism / Q000187:drug effects; D008099:Liver / Q000378:metabolism; D008627:Mercuric Chloride / Q000493:pharmacokinetics* / Q000633:toxicity; D009132:Muscles / Q000378:metabolism; D015430:Weight Gain / Q000187:drug effects
chemical_list: D029941:Fish Proteins; D008627:Mercuric Chloride; D001205:Ascorbic Acid
keywords: Growth; Mercuric chloride; Olive flounder; Tissue mercury content; Vitamin C