title: [A Case of Subacute Thyroiditis during Chemotherapy after Distal Pancreatectomy].
abstract: A 68-year-old woman who underwent distal pancreatectomy combined with resection of the celiac axis had an abdominal wall recurrence and resection 2 years after the first surgery. She was treated with S-1 at an outpatient clinic following the surgery. She returned to the clinic with a high fever after the S-1 administration and was diagnosed with febrile neutropenia. However, treatment for febrile neutropenia including antibiotics and G-CSF did not improve her symptoms. Her history of chronic severe neck pain and painful enlargement of her thyroid gland suggested thyroiditis. After blood tests and thyroid scintigraphy, she was diagnosed with subacute thyroiditis and was treated with prednisolone. Her symptoms improved within a week. Although patients with neutropenia and a high fever during chemotherapy are likely to have febrile neutropenia, the possibility of another cause of neutropenia with fever should be considered if treatments for febrile neutropenia are not effective.
authors.affiliation: Dept. of Surgery, National Hospital Organization, Osaka National Hospital.
authors.forename: Yurina
authors.initials: Y
authors.lastname: Saito
authors.forename: Hisashi
authors.initials: H
authors.lastname: Hara
authors.forename: Masanori
authors.initials: M
authors.lastname: Tsujie
authors.forename: Atsushi
authors.initials: A
authors.lastname: Miyamoto
authors.forename: Tadafumi
authors.initials: T
authors.lastname: Asaoka
authors.forename: Kazuyoshi
authors.initials: K
authors.lastname: Yamamoto
authors.forename: Masakazu
authors.initials: M
authors.lastname: Ikenaga
authors.forename: Michihiko
authors.initials: M
authors.lastname: Miyazaki
authors.forename: Masataka
authors.initials: M
authors.lastname: Ikeda
authors.forename: Motohiro
authors.initials: M
authors.lastname: Hirao
authors.forename: Kazumasa
authors.initials: K
authors.lastname: Fujitani
authors.forename: Mitsugu
authors.initials: M
authors.lastname: Sekimoto
authors.forename: Shoji
authors.initials: S
authors.lastname: Nakamori
mesh_terms: D000368:Aged; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use*; D000963:Antimetabolites / Q000009:adverse effects* / Q000627:therapeutic use; D004338:Drug Combinations; D017809:Fatal Outcome; D005260:Female; D005334:Fever / Q000188:drug therapy; D006801:Humans; D010094:Oxonic Acid / Q000009:adverse effects* / Q000627:therapeutic use; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000188:drug therapy* / Q000473:pathology / Q000601:surgery; D011239:Prednisolone / Q000627:therapeutic use*; D005641:Tegafur / Q000009:adverse effects* / Q000627:therapeutic use; D013968:Thyroiditis, Subacute / Q000139:chemically induced / Q000188:drug therapy*
chemical_list: D000893:Anti-Inflammatory Agents; D000963:Antimetabolites; D004338:Drug Combinations; C079198:S 1 (combination); D005641:Tegafur; D010094:Oxonic Acid; D011239:Prednisolone