title: Papulonodular secondary syphilis: a rare clinic presentation confirmed by serologic and histologic exams.
abstract: Syphilis is a sexually transmitted disease caused by Treponema pallidum and divided into three stages according to the duration of the disease: primary, secondary and tertiary. Secondary syphilis has diverse clinical presentations, such as papular-nodular lesions. This presentation is rare, with 15 cases reported in the literature over the past 20 years. We report a case of secondary syphilis with papular-nodular lesions in a healthy 63-year-old patient, who has presented treponema in immunohistochemical examination of the skin lesions.
authors.affiliation: Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
authors.forename: John Verrinder
authors.initials: JV
authors.lastname: Veasey
authors.affiliation: Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
authors.forename: Rute Facchini
authors.initials: RF
authors.lastname: Lellis
authors.affiliation: Private Practice, Londrina, PR, Brazil.
authors.forename: Maria Fernanda Feitosa de Camargo
authors.initials: MF
authors.lastname: Boin
authors.affiliation: Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Pedro Loureiro
authors.initials: PL
authors.lastname: Porto
authors.affiliation: Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil.
authors.forename: Jessica Chia Sin
authors.initials: JC
authors.lastname: Chen
mesh_terms: D001706:Biopsy; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged; D010413:Penis / Q000473:pathology; D012698:Serologic Tests; D012867:Skin / Q000473:pathology; D013587:Syphilis / Q000473:pathology*; D013591:Syphilis, Cutaneous / Q000473:pathology*