title: Donor Outcomes in Living Donor Liver Transplantation-Analysis of 275 Donors From a Single Centre in India.
abstract: Live donor liver transplantation is the predominant form of liver transplantation in India and in most Asian countries. Donor outcome reports are an important source of information to be shared with prospective donors at the time of informed consent. This is the first donor outcome series from India.
  
  
  
  Analysis of donor characteristics and morbidity of 275 live donors from a single large volume center is documented.
  
  
  
  Two hundred seventy-five patients donated from November 2009 to October 2014, 144 were women and 131 were men, 180 donated to adults and 95 donated to children. Right lobe donors were majority at 62.2% followed by left lateral segment 28%. Two thirds of the live donors did not have any morbidity; 114 complications were encountered in 85 patients. The complications were graded as per Clavien 5 tier grading and major morbidity (grade III b, grade IV grade V) was 4.36%. Postoperative biliary complication was seen in 3 donors.
  
  
  
  This large single-center study is the first donor outcome report from India, and the results are comparable to other published donor series. Documentation and regular audit of donor outcomes is important to help improve the safety of donor hepatectomy and to provide a database for informed consent of prospective donors.
authors.affiliation: 1 Institute of Liver Disease & Transplantation, Global Health City, Chennai, India & National Foundation for Liver Research.
authors.forename: Gomathy
authors.initials: G
authors.lastname: Narasimhan
authors.forename: Mohamed
authors.initials: M
authors.lastname: Safwan
authors.forename: Venugopal
authors.initials: V
authors.lastname: Kota
authors.forename: Mettu S
authors.initials: MS
authors.lastname: Reddy
authors.forename: Anand
authors.initials: A
authors.lastname: Bharathan
authors.forename: Abderrhaim
authors.initials: A
authors.lastname: Dabora
authors.forename: Ilankumaran
authors.initials: I
authors.lastname: Kaliamoorthy
authors.forename: Rathnavel G
authors.initials: RG
authors.lastname: Kanagavelu
authors.forename: Vijaya
authors.initials: V
authors.lastname: Srinivasan
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rela
mesh_terms: D000293:Adolescent; D000328:Adult; D001706:Biopsy; D015992:Body Mass Index; D002648:Child; D046148:Donor Selection; D005260:Female; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D007194:India; D016031:Liver Transplantation / Q000379:methods*; D019520:Living Donors; D008297:Male; D008875:Middle Aged; D061214:Patient Safety; D011183:Postoperative Complications / Q000209:etiology; D011184:Postoperative Period; D011446:Prospective Studies; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D020858:Tissue and Organ Harvesting / Q000009:adverse effects; D055815:Young Adult