title: Pulmonary Involvement in Brucellosis, a Rare Complication of Renal Transplant: Case Report and Brief Review.
abstract: Brucellosis, a disease endemic in many countries including Turkey, is a systemic infectious disease. Brucellosis is rare in renal transplant recipients. Only 4 cases have been reported in the literature. In this report, we describe the clinical manifestations and laboratory findings of a brucellosis case with pulmonary involvement in a renal transplant recipient. A 20-year-old man who had a living-donor kidney transplant 4 months earlier presented to our transplant clinic with fever, cough, and right flank pain. Clarithromycin and ceftriaxone were started for the diagnosis of pneumonia. However, piperacillin/tazobactam, meropenem plus teicoplanin, and antituberculosis treatment were continued because the patient was unresponsive to the initial therapy. Serum Brucella agglutination titer was found to be 1/320. Treatment was started with a 6-week course of oral doxycycline and rifampin, resulting in cure. Brucellosis and especially its pulmonary involvement are rare after kidney transplant. However, in endemic areas,it should be considered as it mimics several other infectious diseases.
authors.affiliation: From the Transplantation Center, Diyarbakır Education and Research Hospital, Diyarbakır, Turkey.
authors.forename: Nurettin
authors.initials: N
authors.lastname: Ay
authors.forename: Safak
authors.initials: S
authors.lastname: Kaya
authors.forename: Melih
authors.initials: M
authors.lastname: Anil
authors.forename: Vahhac
authors.initials: V
authors.lastname: Alp
authors.forename: Unal
authors.initials: U
authors.lastname: Beyazit
authors.forename: Enver
authors.initials: E
authors.lastname: Yuksel
authors.forename: Ramazan
authors.initials: R
authors.lastname: Danis
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002006:Brucellosis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D051436:Renal Insufficiency, Chronic / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents