title: Cognitive Reserve in Dementia: Implications for Cognitive Training.
abstract: Cognitive reserve (CR) is a potential mechanism to cope with brain damage. The aim of this study was to evaluate the effect of CR on a cognitive training (CT) in a group of patients with dementia. Eighty six participants with mild to moderate dementia were identified by their level of CR quantified by the CR Index questionnaire (CRIq) and underwent a cycle of CT. A global measure of cognition mini mental state examination (MMSE) was obtained before (T0) and after (T1) the training. Multiple linear regression analyses highlighted CR as a significant factor able to predict changes in cognitive performance after the CT. In particular, patients with lower CR benefited from a CT program more than those with high CR. These data show that CR can modulate the outcome of a CT program and that it should be considered as a predictive factor of neuropsychological rehabilitation training efficacy in people with dementia.
authors.affiliation: Department of General Psychology, University of PaduaPadova, Italy; Neuromotor Rehabilitation Unit, Casa di Cura Figlie di San CamilloCremona, Italy; Human Inspired Technology Research Centre, University of PaduaPadova, Italy.
authors.forename: Sara
authors.initials: S
authors.lastname: Mondini
authors.affiliation: Department of General Psychology, University of Padua Padova, Italy.
authors.forename: Ileana
authors.initials: I
authors.lastname: Madella
authors.affiliation: Department of General Psychology, University of PaduaPadova, Italy; Human Inspired Technology Research Centre, University of PaduaPadova, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Zangrossi
authors.affiliation: Department of General Psychology, University of Padua Padova, Italy.
authors.forename: Angela
authors.initials: A
authors.lastname: Bigolin
authors.affiliation: Department of General Psychology, University of PaduaPadova, Italy; Neuromotor Rehabilitation Unit, Casa di Cura Figlie di San CamilloCremona, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Tomasi
authors.affiliation: Department of General Psychology, University of Padua Padova, Italy.
authors.forename: Marta
authors.initials: M
authors.lastname: Michieletto
authors.affiliation: Neuromotor Rehabilitation Unit, Casa di Cura Figlie di San Camillo Cremona, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Villani
authors.affiliation: IRCCS Centro S. Giovanni di Dio Fatebenefratelli Brescia, Italy.
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Di Giovanni
authors.affiliation: Department of General Psychology, University of PaduaPadova, Italy; Human Inspired Technology Research Centre, University of PaduaPadova, Italy.
authors.forename: Daniela
authors.initials: D
authors.lastname: Mapelli
keywords: Alzheimer’s disease; cognitive reserve; cognitive training; dementia; rehabilitation