title: [Clinicopathological Outcome of Perforated Colorectal Cancer].
abstract: We investigated the clinicopathological findings of 90 patients with colorectal perforation who underwent emergency surgery between January 2008 and July 2015.T he patients were divided into 2 groups, namely those with perforation due to colorectal cancer(colorectal cancer group, n=20)and those with perforation due to benign colorectal disease(non-colorectal cancer group, n=70).We investigated the clinicopathological findings of the 2 groups.The SOFA score was significantly lower in the colorectal cancer group than in the non-colorectal cancer group.Of the 20 cases of primary cancer, 11 were located in the sigmoid colon; 5, in the rectum; 2, in the transverse colon; 1, in the ascending colon; and 1, in the cecum.The perforation occurred at the tumor site in 8 patients and at the oral site of cancer in 12.Eleven patients had stage II cancer, 1 had stage IIIa, and 8 had stage IV.Ten patients underwent curability A resection; 1, curability B resection; and 8, curability C resection.Recurrence was observed in 6 of the 10 patients who had undergone curability A resection and in 1 patient who had undergone curability B resection.The initial recurrence site was the liver in 3 cases, the peritoneum in 2 cases, and a local site in 2 cases.Even if the patents underwent curative operation, the recurrence rate was high.Therefore, we conclude that adjuvant chemotherapy is required along with careful follow-up.
authors.affiliation: Dept. of Surgery, Mitoyo General Hospital.
authors.forename: Tetsunobu
authors.initials: T
authors.lastname: Udaka
authors.forename: Naoya
authors.initials: N
authors.lastname: Matsumoto
authors.forename: Izuru
authors.initials: I
authors.lastname: Endo
authors.forename: Sumiharu
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Osamu
authors.initials: O
authors.lastname: Yoshida
authors.forename: Hidetoshi
authors.initials: H
authors.lastname: Inokawa
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Kubo
authors.forename: Minoru
authors.initials: M
authors.lastname: Mizuta
mesh_terms: D000368:Aged; D015179:Colorectal Neoplasms / Q000150:complications / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D007416:Intestinal Perforation / Q000209:etiology* / Q000601:surgery; D008297:Male; D009367:Neoplasm Staging; D012008:Recurrence; D016896:Treatment Outcome