title: Antibacterial Activity and Fluoride Release of Glass-Ionomer Cement, Compomer and Zirconia Reinforced Glass-Ionomer Cement.
abstract: BACKGROUND
  The cariostatic property of glass ionomer cement (GIC) stems from its ability to release fluoride into the oral environment. Recently, zirconia reinforced GIC has been launched which promises the protective benefits of glass ionomer while completely eliminating the hazard of mercury.
  
  
  OBJECTIVE
  To evaluate invitro antibacterial activity and fluoride release from two conventional glass ionomer cements (GC II and GC IX), compomer (Compoglass) and a zirconia reinforced glass ionomer cement (Zirconomer).
  
  
  METHODS
  The antibacterial activity of the cement specimens was evaluated against Streptococcus mutans using the agar inhibition test. Zone of inhibition on Mueller-Hinton agar plates was measured after 48 hours. The fluoride release from the cement specimens in ppm were measured at day 1, 7, 14 and 21 using a fluoride ion selective electrode. Data was analysed using one-way and two-way analysis of variance (ANOVA) followed by LSD post-hoc test. A p-value <0.05 was considered statistically significant.
  
  
  RESULTS
  Statistically significant largest zone of inhibition was observed with Zirconomer. Also, significant differences were seen in fluoride release of different materials. At all the time intervals maximum fluoride release was observed with Zirconomer and minimum with Compoglass.
  
  
  CONCLUSIONS
  This invitro investigation has revealed that zirconia reinforced GIC (Zirconomer) had maximum antibacterial activity against S.mutans and fluoride release.
authors.affiliation: Post Graduate Student, Department of Pedodontics and Preventive Dentistry, Hitkarini Dental College and Hospital , Jabalpur, Madhya Pradesh, India .
authors.forename: Sonia
authors.initials: S
authors.lastname: Tiwari
authors.affiliation: Professor, Department of Pedodontics and Preventive Dentistry, College of Dental Sciences , Davangere, Karnataka, India .
authors.forename: Mallikarjuna
authors.initials: M
authors.lastname: Kenchappa
authors.affiliation: Professor and Head, Department of Pedodontics and Preventive Dentistry, Hitkarini Dental College and Hospital , Jabalpur, Madhya Pradesh, India .
authors.forename: Deepak
authors.initials: D
authors.lastname: Bhayya
authors.affiliation: Reader, Department of Pedodontics and Preventive Dentistry, Hitkarini Dental College and Hospital , Jabalpur, Madhya Pradesh, India .
authors.forename: Shilpi
authors.initials: S
authors.lastname: Gupta
authors.affiliation: Reader, Department of Public Health Dentistry, Hitkarini Dental College and Hospital , Jabalpur, Madhya Pradesh, India .
authors.forename: Sudhanshu
authors.initials: S
authors.lastname: Saxena
authors.affiliation: Post Graduate Student, Department of Pedodontics and Preventive Dentistry, Hitkarini Dental College and Hospital , Jabalpur, Madhya Pradesh, India .
authors.forename: Saurabh
authors.initials: S
authors.lastname: Satyarth
authors.affiliation: Senior lecturer, Department of Public Health Dentistry, People's College of Dental Sciences & Research Center , Bhopal, Madhya Pradesh, India .
authors.forename: Aishwarya
authors.initials: A
authors.lastname: Singh
authors.affiliation: Post Graduate Student, Department of Public Health Dentistry, People's College of Dental Sciences & Research Center , Bhopal, Madhya Pradesh, India .
authors.forename: Manoj
authors.initials: M
authors.lastname: Gupta
keywords: Dental caries; Invitro technique; Streptococcus mutans; Zirconium oxide