title: Etiological factors associated with chronic suppurative otitis media in a population of Han adults in China.
abstract: OBJECTIVE
  Risk factors for chronic suppurative otitis media (CSOM) were not clearly established. The study was to investigate the etiological factors for CSOM from a population of Han adults in China.
  
  
  METHODS
  A case-control study was conducted at Second Affiliated Hospital of Xi'an Jiaotong University, School of Medicine in China. A total of 416 individuals participated in this study, which included 206 cases and 210 controls.
  
  
  RESULTS
  Multivariate logistic regression analysis revealed male (OR = 0.42; 95% CI: 0.21-0.83), BMI increasing (OR = 0.85; 95% CI: 0.77-0.93), URTI (OR = 152.85; 95% CI: 34.11-684.93), smoke/passive smoke (OR = 7.11; 95% CI: 3.36-15.07), residential location (urban area) (OR = 0.27; 95% CI: 0.13-0.56), serum calcium increasing (OR = 0.09; 95% CI: 0.01-0.71) were prime risk factors for CSOM. Univariate analysis revealed that low socioeconomic status (OR= 2.33; 95% CI: 1.57-3.45) and hepatitis B (OR = 4.90; 95% CI: 1.82-13.21) were risk factors together with the above variables.
  
  
  CONCLUSIONS
  This study has identified several variables as risk factors for CSOM, suggesting better healthcare, living condition, as well as better nutrition might decrease the development of CSOM. Further studies are necessary to assess the outcome of CSOM after interventions in the etiological factors.
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Junli
authors.initials: J
authors.lastname: Wang
authors.affiliation: b Department of Neurosurgery , the First Affiliated Hospital of Xi'an Medical University , Xi'an , PR China.
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Min
authors.initials: M
authors.lastname: Xu
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Junbao
authors.initials: J
authors.lastname: Wu
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Ting
authors.initials: T
authors.lastname: Wang
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Jian
authors.initials: J
authors.lastname: Zhao
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Qing
authors.initials: Q
authors.lastname: Zhang
authors.affiliation: a Department of Otorhinolaryngology-HNS , Second Affiliated Hospital, Xi'an Jiaotong University School of Medicine , Xi'an , PR China ;
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D002908:Chronic Disease; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010035:Otitis Media, Suppurative / Q000453:epidemiology / Q000209:etiology*; D055815:Young Adult
keywords: Suppurative otitis media; case-control study; risk factor