title: Alcohol Intervention for Adolescents with Fetal Alcohol Spectrum Disorders: Project Step Up, a Treatment Development Study.
abstract: Project Step Up proposed to reduce alcohol consumption and alcohol-related negative outcomes in adolescents with fetal alcohol spectrum disorders (FASD).
  
  
  
  The 54 participants (30 females, 24 males) were assigned to either Project Step Up Intervention (SUI) or Control conditions and were assessed prior to intervention, immediately following intervention, and at 3-month follow-up. Adolescents in the SUI condition participated in a 6-week, 60-minute group intervention that provided alcohol education and promoted adaptive responses to alcohol-related social pressures. Caregivers attended concurrent but separate sessions on the effects of prenatal alcohol exposure on the brain and how to handle parenting challenges associated with alcohol use in teens with FASD.
  
  
  
  Thirty-three percent (n = 18) of adolescents were classified as light/moderate drinkers, and 67% (n = 36) were abstinent/infrequent drinkers based on their lifetime drinking histories. Results revealed a significant decrease in self-reported alcohol risk and in alcohol-related negative behaviors (Cohen's d = 1.08 and 0.99) in light/moderate drinkers in the SUI compared to the Control group. These results were partially sustained at 3-month follow-up. Furthermore, adolescents in the abstinent/infrequent group exhibited no increase in alcohol-related outcomes suggesting that the group intervention used in this study was not iatrogenic.
  
  
  
  The success of this treatment development study provides preliminary support for effective treatment of adolescents with FASD to prevent or reduce alcohol use and its negative consequences in this high risk population.
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, California.
authors.forename: Mary J
authors.initials: MJ
authors.lastname: O'Connor
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, California.
authors.forename: Justin
authors.initials: J
authors.lastname: Quattlebaum
authors.affiliation: Department of Psychiatry and Biobehavioral Sciences, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles (UCLA), Los Angeles, California.
authors.forename: Marleen
authors.initials: M
authors.lastname: Castañeda
authors.affiliation: Departments of Human Genetics and Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, California.
authors.forename: Katrina M
authors.initials: KM
authors.lastname: Dipple
mesh_terms: D000293:Adolescent; D064829:Alcohol Abstinence / Q000523:psychology / Q000639:trends; D000428:Alcohol Drinking / Q000523:psychology / Q000628:therapy*; D061345:Early Medical Intervention / Q000379:methods* / Q000639:trends; D005260:Female; D063647:Fetal Alcohol Spectrum Disorders / Q000175:diagnosis* / Q000523:psychology / Q000628:therapy*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D010865:Pilot Projects; D011247:Pregnancy; D011297:Prenatal Exposure Delayed Effects / Q000175:diagnosis / Q000523:psychology / Q000628:therapy; D057566:Self Report; D016896:Treatment Outcome
keywords: Adolescents; Alcohol Intervention; Alcohol Misuse; Fetal Alcohol Spectrum Disorders; Prenatal Alcohol Exposure