title: Implant-Based Breast Reconstruction Using a Polyester Mesh (Surgimesh-PET): A Retrospective Single-Center Study.
abstract: BACKGROUND
  Although the introduction of acellular dermal matrices is considered one of the most important advancements in alloplastic breast reconstruction, costs and local policy limit their use in Italy. The purpose of this study was to assess short-term outcomes following Surgimesh-PET-based breast reconstruction.
  
  
  METHODS
  A single-center, retrospective, case-control study was performed from January 1, 2012, to December 31, 2013, by enrolling 206 breast reconstructions performed in 196 patients after oncologic (n = 200) or prophylactic (n = 6) mastectomy. Group A included 63 patients who underwent 70 immediate Surgimesh-PET-assisted breast reconstructions, and group B included 133 patients who underwent 136 standard breast reconstructions.
  
  
  RESULTS
  No significant differences between groups occurred for early postoperative complications (p = 0.610), major complications that required surgical revision (p = 0.887), volume (p = 0.498) or width of the prosthesis (p = 0.201), skin-sparing mastectomy (p = 0.315), or axillary surgery (p = 0.265). Multivariate logistic regression showed that prior radiotherapy was the only significant variable for early postoperative complications in both whole series (p = 0.011) and group B (p = 0.046), whereas body mass index greater than 25 was an independent predictor in group A (p = 0.041). Prior radiotherapy was the only variable that reached statistical significance in the multivariate model for major complications in the whole series (p = 0.005).
  
  
  CONCLUSIONS
  Short-term outcomes of Surgimesh-PET-based alloplastic breast reconstruction are promising. Further studies are needed to evaluate the long-term results of this surgical approach.
  
  
  METHODS
  Therapeutic, III.
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Ilaria
authors.initials: I
authors.lastname: Baldelli
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Gaia
authors.initials: G
authors.lastname: Cardoni
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Simonetta
authors.initials: S
authors.lastname: Franchelli
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Piero
authors.initials: P
authors.lastname: Fregatti
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Daniele
authors.initials: D
authors.lastname: Friedman
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Marianna
authors.initials: M
authors.lastname: Pesce
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Erica
authors.initials: E
authors.lastname: Ponte
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Gregorio
authors.initials: G
authors.lastname: Santori
authors.affiliation: Genoa, Italy.|From the Department of Surgical Sciences and Integrated Diagnostics, University of Genoa; and the Plastic Surgery Department, IRCCS San Martino University Hospital, National Institute for Cancer Research.
authors.forename: Pierluigi
authors.initials: P
authors.lastname: Santi
mesh_terms: D000328:Adult; D018427:Breast Implants; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D016462:Mammaplasty / Q000379:methods*; D008875:Middle Aged; D020360:Neoadjuvant Therapy; D011091:Polyesters; D011183:Postoperative Complications / Q000209:etiology* / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D012086:Reoperation; D012189:Retrospective Studies; D012307:Risk Factors; D013526:Surgical Mesh
chemical_list: D011091:Polyesters