title: Higher Serum Bisphenol A Levels in Diabetic Hemodialysis Patients.
abstract: BACKGROUND
  Bisphenol A (BPA) has been implicated as an 'endocrine disruptor'. We aimed at exploring the association between serum BPA levels and patient characteristics, particularly the presence of diabetes mellitus, and laboratory parameters in hemodialysis patients.
  
  
  METHODS
  This study included 47 chronic hemodialysis patients. Patient characteristics were recorded. Blood was drawn before and after hemodialysis session. Serum BPA levels were measured by the high-performance-liquid-chromatography and laboratory parameters were measured by using standard methods.
  
  
  RESULTS
  In hemodialysis patients, postdialysis serum BPA levels were significantly higher than predialysis after a single hemodialysis session (5.57 ± 1.2 vs. 4.06 ± 0.73, p < 0.0001). Predialysis serum BPA levels were significantly higher in patients with diabetes than non-diabetics (4.4 ± 0.6 vs. 3.9 ± 0.7, p = 0.025). No association was found between serum BPA levels and patient characteristics, and particularly laboratory parameters.
  
  
  CONCLUSIONS
  Serum BPA levels were rising significantly after a single dialysis session. Diabetic hemodialysis patients had higher predialysis serum BPA levels.
authors.affiliation: Department of Nephrology, Faculty of Medicine, Mustafa Kemal University, Antakya, Hatay, Turkey.
authors.forename: Faruk
authors.initials: F
authors.lastname: Turgut
authors.forename: Sana
authors.initials: S
authors.lastname: Sungur
authors.forename: Ramazan
authors.initials: R
authors.lastname: Okur
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yaprak
authors.forename: Muge
authors.initials: M
authors.lastname: Ozsan
authors.forename: Ihsan
authors.initials: I
authors.lastname: Ustun
authors.forename: Cumali
authors.initials: C
authors.lastname: Gokce
mesh_terms: D000328:Adult; D000368:Aged; D001559:Benzhydryl Compounds / Q000097:blood*; D002851:Chromatography, High Pressure Liquid; D019411:Clinical Laboratory Techniques; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000097:blood*; D052244:Endocrine Disruptors / Q000097:blood; D006801:Humans; D007676:Kidney Failure, Chronic / Q000097:blood*; D008875:Middle Aged; D010636:Phenols / Q000097:blood*; D006435:Renal Dialysis; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D052244:Endocrine Disruptors; D010636:Phenols; C006780:bisphenol A; D000098826:Bisphenol A Compounds