title: Inverse psoriasis treated with ustekinumab.
abstract: Inverse psoriasis is characterised by the involvement of flexural skin folds. This form of psoriasis has distinct clinical and therapeutic features. This report refers to the case of a 48-year-old Caucasian man who was observed in our department, with a clinically and biopsy proven diagnosis of inverse psoriasis. For 2 years, the patient was treated with different combinations of corticosteroids, vitamin D analogues and methotrexate, with no satisfactory response. Given the lack of a clinical response and comorbidities, latent tuberculosis was excluded, and we started treatment with ustekinumab. We chose this biological agent because the patient was a long-distance truck driver and refused the possibility of autoinjections. The patient underwent three ustekinumab injections, which resulted in significant improvement of pruritus, erythaematous lesions and quality of life.
authors.affiliation: Department of Dermatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
authors.forename: Manuel António
authors.initials: MA
authors.lastname: Campos
authors.affiliation: Department of Dermatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
authors.forename: Paulo
authors.initials: P
authors.lastname: Varela
authors.affiliation: Department of Dermatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
authors.forename: Armando
authors.initials: A
authors.lastname: Baptista
authors.affiliation: Department of Dermatology, Centro Hospitalar de Vila Nova de Gaia/Espinho, Vila Nova de Gaia, Portugal.
authors.forename: Ana Isabel
authors.initials: AI
authors.lastname: Moreira
mesh_terms: D003879:Dermatologic Agents / Q000008:administration & dosage* / Q000627:therapeutic use; D006801:Humans; D007267:Injections; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000188:drug therapy*; D011788:Quality of Life; D016896:Treatment Outcome; D000069549:Ustekinumab / Q000008:administration & dosage* / Q000627:therapeutic use
chemical_list: D003879:Dermatologic Agents; D000069549:Ustekinumab