title: Takayasu arteritis presenting with malignant hypertension; a rare manifestation of a rare disease: a case report and review of the literature.
abstract: Takayasu arteritis (TA) is a chronic inflammatory and obliterative disease of large vessels, which mainly affects the aorta and its major branches. TA can lead to renal failure and renovascular hypertension in 60% of patients; it is rare in children aged <10 years and, more rarely, it presents with malignant hypertension in the paediatric age group. Here we present a case of 9-year-old boy with TA who presented with malignant hypertension and required surgical intervention to control the blood pressure. Subsequently, his medications were titrated using 24 h ambulatory blood pressure monitoring (ABPM) and is doing well on follow-up.
authors.affiliation: Senior Resident, Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.
authors.forename: Bhupeshwari
authors.initials: B
authors.lastname: Patel
authors.affiliation: Assistant Professor, Department of Paediatrics, Chirayu Medical College, Bhopal, Madhya Pradesh, India.
authors.forename: Astha
authors.initials: A
authors.lastname: Tiwari
authors.affiliation: Senior Resident, Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.
authors.forename: Shiv Ram Krishna
authors.initials: SR
authors.lastname: Dubey
authors.affiliation: Assistant Professor, Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India drgcbhatt@gmail.com.
authors.forename: Girish C
authors.initials: GC
authors.lastname: Bhatt
authors.affiliation: Department of Urosurgery, Chirayu Medical College, Bhopal, Madhya Pradesh, India.
authors.forename: Punit
authors.initials: P
authors.lastname: Tiwari
authors.affiliation: Assistant Professor, Department of Paediatrics, All India Institute of Medical Sciences (AIIMS), Bhopal, Madhya Pradesh, India.
authors.forename: Bhavna Dhingra
authors.initials: BD
authors.lastname: Bhan
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use; D002648:Child; D006801:Humans; D006974:Hypertension, Malignant / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000209:etiology* / Q000601:surgery; D008297:Male; D009392:Nephrectomy; D035583:Rare Diseases; D013625:Takayasu Arteritis / Q000150:complications* / Q000175:diagnosis
chemical_list: D000959:Antihypertensive Agents
keywords: Takayasu arteritis (TA); malignant hypertension; nephrectomy