title: [Chronic recurrent multifocal osteomyelitis of the spine : Children and adolescent].
abstract: Chronic non-bacterial osteomyelitis (CNO) in childhood and adolescence is a non-infectious autoinflammatory disease of the bone with partial involvement of adjacent joints and soft tissue. The etiology is unknown. The disease can occur singular or recurrent. Individual bones can be affected and multiple lesions can occur. Chronic recurrent multifocal osteomyelitis (CRMO) shows the whole picture of CNO. Accompanying but temporally independent of the bouts of osteomyelitis, some patients show manifestations in the skin, eyes, lungs and the gastrointestinal tract. The article gives an overview of the clinical manifestations, diagnostic procedures, and treatment options for CRMO involvement of the spine based on the current literature and our own cases.
authors.affiliation: Klinik und Poliklinik für Orthopädie, Unfallchirurgie und plastische Chirurgie, Universitätsklinikum Leipzig AöR, Liebigstrasse 18, 04103, Leipzig, Deutschland.
authors.forename: N H
authors.initials: NH
authors.lastname: von der Höh
authors.affiliation: Klinik und Poliklinik für Orthopädie, Unfallchirurgie und plastische Chirurgie, Universitätsklinikum Leipzig AöR, Liebigstrasse 18, 04103, Leipzig, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Völker
authors.affiliation: Wirbelsäulenchirurgie, Muskulo-Skelettal Zentrum, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Schweiz.
authors.forename: D
authors.initials: D
authors.lastname: Jeszenszky
authors.affiliation: Klinik und Poliklinik für Orthopädie, Unfallchirurgie und plastische Chirurgie, Universitätsklinikum Leipzig AöR, Liebigstrasse 18, 04103, Leipzig, Deutschland. christoph.eckhard.heyde@medizin.uni-leipzig.de.
authors.forename: C-E
authors.initials: CE
authors.lastname: Heyde
mesh_terms: D000293:Adolescent; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D002648:Child; D002675:Child, Preschool; D003131:Combined Modality Therapy / Q000379:methods; D003937:Diagnosis, Differential; D019317:Evidence-Based Medicine; D005260:Female; D006801:Humans; D007103:Immobilization / Q000379:methods*; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D010019:Osteomyelitis / Q000175:diagnosis* / Q000628:therapy*; D012008:Recurrence; D013122:Spinal Diseases / Q000175:diagnosis* / Q000628:therapy*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents
keywords: Differential diagnosis; Non bacterial osteomyelitis; Spinal deformity; Spinal diseases; Spondylodesis