title: Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review.
abstract: The etiology of bronchiolitis obliterans organizing pneumonia (BOOP) remains controversial. While it has been reportedly associated with several connective tissue disorders, there are only rare reports of BOOP associated with systemic lupus erythematosus (SLE). Herein, we report a 56-year-old female patient who presented with dyspnea on exertion, cough, fever, and joint pain of her left wrist and fingers as initial symptoms. Laboratory tests revealed positivity for anti-nuclear antibody, anti-Ro, and anti-double strand DNA antibody. In this case, the patient with SLE had respiratory illness as the initial symptom due to BOOP in the absence of clear etiology. The diagnosis of BOOP was confirmed by thoracic surgery biopsy. Her respiratory symptoms and radiologic findings significantly improved following prednisolone treatment.
authors.affiliation: Division of Allergy, Immunology and Rheumatology, Chiayi Christian Hospital, Chiayi 60002, Taiwan.
authors.forename: Hung-Ping
authors.initials: HP
authors.lastname: Wang
authors.affiliation: Division of Allergy, Immunology and Rheumatology, Chiayi Christian Hospital, Chiayi 60002, Taiwan.
authors.forename: Chun-Ming
authors.initials: CM
authors.lastname: Chen
authors.affiliation: Department of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi 60002, Taiwan.
authors.forename: Yih-Yuan
authors.initials: YY
authors.lastname: Chen
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi 60002, Taiwan; College of Nursing, Dayeh University, Changhua 51591, Taiwan; Department of Respiratory Therapy, China Medical University, Taichung 40402, Taiwan.
authors.forename: Wei
authors.initials: W
authors.lastname: Chen