title: Major Depression in Long-Term Oxygen Therapy Dependent Chronic Obstructive Pulmonary Disease.
abstract: OBJECTIVE
  We aimed to investigate the frequency of major depression (MD) in long-term oxygen therapy (LTOT) dependent chronic obstructive pulmonary disease (COPD) patients and the effect of depression on patients' compliance with the treatment.
  
  
  METHODS
  Fifty-four consecutive patients were enrolled in the study and diagnosed as stage 4 COPD according to Global Initiative for Chronic Obstructive Lung Disease guideline. MD was diagnosed with the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition/Clinical Version.
  
  
  RESULTS
  Thirty-four (63.0%) patients had MD. MD frequency was significantly higher in patients who were noncompliant with LTOT compared with compliant patients.
  
  
  CONCLUSIONS
  MD is a common psychiatric disorder in COPD patients receiving LTOT.
authors.affiliation: Fatih Kayhan, MD, is Psychiatrist, Faculty of Medicine, Department of Psychiatry, Selcuk University, Konya, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Kayhan
authors.affiliation: Faik İlik, MD, is Neurologist, Faculty of Medicine, Department of Neurology, Başkent University, Konya, Turkey.
authors.forename: Faik
authors.initials: F
authors.lastname: Ilik
authors.affiliation: Harun Karamanli, MD, is Chest Disease Specialist, Department of Chest Diseases, Chest Disease and Chest Surgery Training and Research Hospital, Ankara, Turkey.
authors.forename: Harun
authors.initials: H
authors.lastname: Karamanli
authors.affiliation: Ahmet Cemal Pazarli, MD, is Chest Disease Specialist, Department of Chest Diseases, Elbistan State Hospital, Kahramanmaraş, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Cemal Pazarli
authors.affiliation: Ayşegül Kayhan, MD, is Radiologist, Department of Radiology, Konya Training and Research Hospital, Konya, Turkey.
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Kayhan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D003865:Major Depressive Disorder / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010102:Oxygen Inhalation Therapy / Q000706:statistics & numerical data*; D010349:Patient Compliance / Q000706:statistics & numerical data*; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology*; D014421:Turkey / Q000453:epidemiology
keywords: Chronic obstructive pulmonary disease; depression; long-term oxygen therapy