title: Increased Coronary Perivascular Adipose Tissue Volume in Patients With Vasospastic Angina.
abstract: BACKGROUND
  Recent studies have suggested that coronary perivascular adipose tissue (PVAT) impairs coronary vasomotion, so we examined whether PVAT is increased at the spastic coronary segment in patients with vasospastic angina (VSA).
  
  
  RESULTS
  PVAT volume in the left anterior descending (LAD) coronary arteries on CT coronary angiography was significantly increased in 48 VSA patients with LAD spasm compared with 18 controls (30.7±2.0 vs. 21.0±3.2 cm(3), P=0.01), whereas that of total epicardial adipose tissue was comparable between the 2 groups.
  
  
  CONCLUSIONS
  The results suggested an important role of PVAT in the pathogenesis of coronary spasm. (Circ J 2016; 80: 1653-1656).
authors.affiliation: Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Ohyama
authors.forename: Yasuharu
authors.initials: Y
authors.lastname: Matsumoto
authors.forename: Kensuke
authors.initials: K
authors.lastname: Nishimiya
authors.forename: Kiyotaka
authors.initials: K
authors.lastname: Hao
authors.forename: Ryuji
authors.initials: R
authors.lastname: Tsuburaya
authors.forename: Hideki
authors.initials: H
authors.lastname: Ota
authors.forename: Hirokazu
authors.initials: H
authors.lastname: Amamizu
authors.forename: Hironori
authors.initials: H
authors.lastname: Uzuka
authors.forename: Jun
authors.initials: J
authors.lastname: Takahashi
authors.forename: Kenta
authors.initials: K
authors.lastname: Ito
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shimokawa
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000503:physiopathology; D000328:Adult; D000368:Aged; D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000503:physiopathology; D017023:Coronary Angiography; D003329:Coronary Vasospasm / Q000000981:diagnostic imaging / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000000981:diagnostic imaging / Q000503:physiopathology