title: In ovo tris(2-butoxyethyl) phosphate concentrations significantly decrease in late incubation after a single exposure via injection, with no evidence of effects on hatching success or latent effects on growth or reproduction in zebra finches.
abstract: Zebra finch (Taeniopygia guttata) eggs were injected with the organophosphate triester flame retardant tris(2-butoxyethyl) phosphate (TBOEP) at 0 μg/g, 0.01 μg/g, 1 μg/g, 10 μg/g, or 50 μg/g egg. Subsets of high-dose eggs were collected throughout incubation to measure TBOEP, which started declining in late incubation and then decreased rapidly to 28% of injected concentration by hatching. The authors found no effects of TBOEP on survival, growth, or reproduction even at very high doses. Environ Toxicol Chem 2017;36:83-88. © 2016 SETAC.
authors.affiliation: Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.|Environment and Climate Change Canada, Ecotoxicology and Wildlife Health Division, Pacific Wildlife Research Centre, Delta, British Columbia, Canada.
authors.forename: Margaret L
authors.initials: ML
authors.lastname: Eng
authors.affiliation: Environment and Climate Change Canada, Ecotoxicology and Wildlife Health Division, National Wildlife Research Centre, Ottawa, Ontario, Canada.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Letcher
authors.affiliation: Department of Biological Sciences, Simon Fraser University, Burnaby, British Columbia, Canada.
authors.forename: Tony D
authors.initials: TD
authors.lastname: Williams
authors.affiliation: Environment and Climate Change Canada, Ecotoxicology and Wildlife Health Division, Pacific Wildlife Research Centre, Delta, British Columbia, Canada.
authors.forename: John E
authors.initials: JE
authors.lastname: Elliott
mesh_terms: D000818:Animals; D004305:Dose-Response Relationship, Drug; D004785:Environmental Pollutants / Q000633:toxicity*; D005260:Female; D005411:Flame Retardants / Q000633:toxicity*; D009943:Organophosphorus Compounds / Q000633:toxicity*; D010063:Ovum / Q000187:drug effects*; D046109:Passeriformes / Q000254:growth & development*; D012098:Reproduction / Q000187:drug effects*
chemical_list: D004785:Environmental Pollutants; D005411:Flame Retardants; D009943:Organophosphorus Compounds; C013320:tris(2-butoxyethyl) phosphate
keywords: Avian toxicity; Developmental toxicity; Flame retardant; Metabolism; Organophosphate; Organophosphate flame retardant; Passerine