title: Multi-component self-assembled anti-tumor nano-vaccines based on MUC1 glycopeptides.
abstract: Novel multi-component self-assembled nano-vaccines containing both Pam3CSK4 and CpG were developed for the first time. These multi-component vaccines could effectively activate the macrophages in vitro and elicit strong antibody immune responses and anti-tumor immune responses in vivo.
authors.affiliation: Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology (Ministry of Education), Department of Chemistry, Tsinghua University, Beijing 100084, P.R. China. liym@mail.tsinghua.edu.cn.
authors.forename: Z Y
authors.initials: ZY
authors.lastname: Sun
authors.forename: P G
authors.initials: PG
authors.lastname: Chen
authors.forename: Y F
authors.initials: YF
authors.lastname: Liu
authors.forename: B D
authors.initials: BD
authors.lastname: Zhang
authors.forename: J J
authors.initials: JJ
authors.lastname: Wu
authors.forename: Y X
authors.initials: YX
authors.lastname: Chen
authors.forename: Y F
authors.initials: YF
authors.lastname: Zhao
authors.forename: Y M
authors.initials: YM
authors.lastname: Li
mesh_terms: D019496:Cancer Vaccines / Q000138:chemical synthesis* / Q000737:chemistry / Q000276:immunology; D006801:Humans; D018396:Mucin-1 / Q000737:chemistry* / Q000276:immunology
chemical_list: D019496:Cancer Vaccines; C060192:MUC1 protein, human; D018396:Mucin-1