title: [Analyses of chronic otitis media with intact tympanic membrane concurrent with intracranial complication].
abstract: OBJECTIVE
  To investigate the clinical and imaging characteristics of chronic otitis media with intact tympanic membrane.
  
  
  METHODS
  Ten patients were retrospective studied in the department of otorhinolaryngology of Guangdong general hospital from December 2006 to January 2015. The clinical characteristics of their manifestations, audiology and imaging examinations were analyzed.
  
  
  RESULTS
  All the cases could be divided into two groups: the intracranial complication group who was primarily diagnosed as intracranial complications, and the hearing loss group who primarily complained of hearing loss. Five cases belonged to the first group, which include 1 cerebellar abscess, 3 meningitis and 1 meningoencephalitis, 2 of them were profound hearing loss, 2 were mixed hearing loss, and 1 was normal hearing. The other 5 cases belonged to the hearing loss group, 3 were mixed deafness, 2 were conductive deafness. All the case showed positive high-resolution computed tomography (HRCT) features. In the first group, four cases showed the soft tissue shadow in tympanic antrum/superior tympanic pouch and 1 case showed a wide damage of skull base, in addition to intracranial complications. In the second group, five cases showed soft tissue imaging in tympanic antrum/superior tympanic pouch. Pathology showed that 2 cases were cholesterol granuloma(one was in the first group and the other was in the second group), 4 were intracranial inflammatory(the first group) and 4 were cholesteatoma(the seond group).
  
  
  CONCLUSIONS
  In chronic otitis media with intact tympanic membrane, intracranial complications may be the primarily diagnosis, which should be paid much attention by multidisciplinary team. HRCT and audiology were valuable for early diagnosis.
authors.affiliation: Department of Otorhinolaryngology, Guangdong General Hospital and Guangdong Academy of Medical Science, Guangzhou 510080, China.
authors.forename: Xiaoqian
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Otorhinolaryngology, Guangdong General Hospital and Guangdong Academy of Medical Science, Guangzhou 510080, China.
authors.forename: Peina
authors.initials: P
authors.lastname: Wu
authors.affiliation: Department of Otorhinolaryngology, Guangdong General Hospital and Guangdong Academy of Medical Science, Guangzhou 510080, China.
authors.forename: Hongming
authors.initials: H
authors.lastname: Huang
authors.affiliation: Department of Otorhinolaryngology, Guangdong General Hospital and Guangdong Academy of Medical Science, Guangzhou 510080, China.
authors.forename: Min
authors.initials: M
authors.lastname: Fu
authors.affiliation: Department of Otorhinolaryngology, Guangdong General Hospital and Guangdong Academy of Medical Science, Guangzhou 510080, China.
authors.forename: Runmei
authors.initials: R
authors.lastname: Ge
mesh_terms: D001922:Brain Abscess / Q000209:etiology; D002526:Cerebellar Diseases / Q000209:etiology; D002781:Cholesteatoma / Q000473:pathology; D002908:Chronic Disease; D006099:Granuloma / Q000473:pathology; D034381:Hearing Loss; D006314:Hearing Loss, Conductive; D006801:Humans; D008581:Meningitis / Q000209:etiology; D010033:Otitis Media / Q000150:complications / Q000473:pathology*; D012189:Retrospective Studies; D014432:Tympanic Membrane