title: Lung Transplant Recipient with Pulmonary Alveolar Proteinosis.
abstract: Pulmonary alveolar proteinosis (PAP) is a progressive lung disease characterized by accumulated surfactant-like lipoproteinaceous material in the alveoli and distal bronchioles. This accumulation is the result of impaired clearance by alveolar macrophages. PAP has been described in 11 solid organ transplant recipients, 9 of whom were treated with mammalian target of rapamycin inhibitors. We report a case of a lung transplant recipient treated with prednisone, mycophenolate mofetil (MMF), and tacrolimus who ultimately developed PAP, which worsened when MMF was replaced with everolimus.
authors.affiliation: Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: Sofya
authors.identifier: 0000-0003-2821-8776
authors.initials: S
authors.lastname: Tokman
authors.affiliation: Department of Pathology, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: M Frances
authors.initials: MF
authors.lastname: Hahn
authors.affiliation: Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: Hesham
authors.initials: H
authors.lastname: Abdelrazek
authors.affiliation: Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: Tanmay S
authors.identifier: 0000-0001-9079-709X
authors.initials: TS
authors.lastname: Panchabhai
authors.affiliation: Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: Vipul J
authors.initials: VJ
authors.lastname: Patel
authors.affiliation: Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: Rajat
authors.initials: R
authors.lastname: Walia
authors.affiliation: Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ 85013, USA.
authors.forename: Ashraf
authors.identifier: 0000-0001-9168-7431
authors.initials: A
authors.lastname: Omar