title: The chorionic bump: Etiologic insights from two pathologic pregnancies.
abstract: The clinical significance and etiology of the chorionic bump remain unclear. We describe two pregnancies characterized by chorionic bumps, which subsequently were diagnosed with a complete mole and trisomy 18, respectively. We hypothesize that placental pathology, including edema and hydropic villi, may contribute to or cause the sonographic finding of some chorionic bumps. An association between chorionic bumps and aneuploidy awaits future study. © 2016 Wiley Periodicals, Inc. J Clin Ultrasound 44:452-454, 2016.
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine.
authors.forename: Joseph R
authors.initials: JR
authors.lastname: Wax
authors.affiliation: Department of Pathology, Maine Medical Center, Portland, Maine.
authors.forename: Hagen
authors.initials: H
authors.lastname: Blaszyk
authors.affiliation: Department of Pathology, Maine Medical Center, Portland, Maine.
authors.forename: Michael
authors.initials: M
authors.lastname: Jones
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine.
authors.forename: Angelina
authors.initials: A
authors.lastname: Cartin
authors.affiliation: Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, Maine.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Pinette
mesh_terms: D000025:Abortion, Eugenic; D000328:Adult; D002823:Chorion / Q000002:abnormalities* / Q000000981:diagnostic imaging*; D002887:Chromosomes, Human, Pair 18; D005260:Female; D006406:Hematoma / Q000000981:diagnostic imaging*; D006801:Humans; D008875:Middle Aged; D010920:Placenta / Q000000981:diagnostic imaging; D011247:Pregnancy; D011248:Pregnancy Complications / Q000000981:diagnostic imaging*; D011261:Pregnancy Trimester, First; D011271:Pregnancy, Ectopic / Q000000981:diagnostic imaging*; D014314:Trisomy / Q000175:diagnosis; D000073842:Trisomy 18 Syndrome; D016216:Ultrasonography, Prenatal / Q000379:methods*; D055815:Young Adult
keywords: aneuploidy; chorionic bump; gestational trophoblastic disease; ultrasound