title: [The immunomodulatory role of retinal microglial cells in age-related macular degeneration].
abstract: Age-related macular degeneration (AMD) is one of the major causes of visual impairment in the elder population. Recent studies have revealed that retinal microgliacytes may play an important role in the pathogenesis of AMD, and the activation of retinal microglia could regulate the progress of AMD. The immunomodulatory role of retinal microglial cells is reviewed in this article, so as to investigate the mechanism and provide new insight for prevention and treatment of AMD.
authors.affiliation: Department of Opthalmology, Affiliated First People's Hospital, Shanghai Jiaotong University, Shanghai Key Laboratory of Ocular Fundus Disease, Shanghai 200080, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Zhang
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Sun
mesh_terms: D018450:Disease Progression; D006801:Humans; D056747:Immunomodulation; D008268:Macular Degeneration / Q000209:etiology / Q000276:immunology*; D017628:Microglia / Q000276:immunology*; D012160:Retina / Q000166:cytology*