title: [Relationship between overweight/obesity and hypertension among adults in China: a prospective study].
abstract: OBJECTIVE
  To evaluate the influence of overweight/obesity on the incidence of hypertension among adults in China.
  
  
  METHODS
  The subjects of this prospective study were 13 739 Chinese adults aged 35-74 years recruited at the baseline surveys of China Multicenter Collaborative Study of Cardiovascular Disease Epidemiology and International Collaborative Study of Cardiovascular Disease in Asian. Baseline surveys were conducted in 1998 and during 2000-2001, respectively, and the follow-up was conducted during 2007-2008. According to the body mass index, the subjects were divided into four groups: underweight group(<18.5 kg/m(2)), normal weight group(18.5-23.9 kg/m(2)), overweight group(24.0-27.9 kg/m(2))and obesity group(≥28.0 kg/m(2)). Age-standardized cumulative incidence of hypertension was calculated for each group, respectively. The relative risks(RRs)and 95% confidence intervals(CIs)for the incidence of hypertension of underweight, overweight and obesity groups were estimated by using generalized linear regression model with normal weight group as reference.
  
  
  RESULTS
  During 8.1 years of follow-up, 4 271 hypertension cases were detected(2 012 in men and 2 259 in women). Age-standardized cumulative incidence of hypertension for the underweight, normal weight, overweight and obesity groups were 20.3%, 30.9%, 43.6% and 50.8% in men, respectively; and 22.9%, 30.4%, 41.1% and 50.8% in women, respectively. Compared with the normal weight group, multivariate-adjusted RR(95% CI)for the incidence of hypertension in underweight, overweight and obesity groups were 0.78(0.64-0.95), 1.22(1.13-1.30)and 1.28(1.16-1.42)in men, respectively; and 0.89(0.77-1.03), 1.16(1.09-1.23)and 1.28(1.18-1.38)in women, respectively. The overweight and obese subjects had higher risk for the incidence of hypertension, with the population attributable risk proportion of 7.4% in men and 8.8% in women, respectively.
  
  
  CONCLUSIONS
  Overweight or obese people are at an increased risk of developing hypertension, thus prevention and control of overweight/obesity are needed to reduce hypertension incidence among adults in China.
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: B Y
authors.initials: BY
authors.lastname: Feng
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: J C
authors.initials: JC
authors.lastname: Chen
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: J F
authors.initials: JF
authors.lastname: Huang
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: J X
authors.initials: JX
authors.lastname: Li
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: L C
authors.initials: LC
authors.lastname: Zhao
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: J
authors.initials: J
authors.lastname: Cao
authors.affiliation: Department of Epidemiology, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangdong Cardiovascular Institute, Guangzhou 510080, China.
authors.forename: X Q
authors.initials: XQ
authors.lastname: Liu
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: C
authors.initials: C
authors.lastname: Huang
authors.affiliation: Department of Chronic and Non-communicable Disease Control and Prevention, Sichuan Provincial Center for Disease Control and Prevention, Chengdu 610044, China.
authors.forename: Y
authors.initials: Y
authors.lastname: Deng
authors.affiliation: Department of Cardiology, Putuo General Hospital, Putuo Cardiovascular Institute of Zhejiang Province, Zhoushan 316100, China.
authors.forename: L S
authors.initials: LS
authors.lastname: Ruan
authors.affiliation: Department of Cardiovascular Diseases, Yuxian People's Hospital of Shanxi Province, Yangquan 045100, China.
authors.forename: D S
authors.initials: DS
authors.lastname: Guo
authors.affiliation: Department of Cardiology, Fujian Provincial Hospital, Fuzhou 350001, China.
authors.forename: L
authors.initials: L
authors.lastname: Yu
authors.affiliation: Non-communicable Disease Control and Prevention, Guangxi Zhuang Automous Region Center for Disease Control and Prevention, Nanning 530021, China.
authors.forename: N Y
authors.initials: NY
authors.lastname: Chen
authors.affiliation: Hanzhong Cardiovascular Institute of Shunaxi Province, Hanzhong 723000, China.
authors.forename: R H
authors.initials: RH
authors.lastname: Yang
authors.affiliation: Non-communicable Disease Control and Prevention, Jintan Center for Disease Control and Prevention, Changzhou 213200, China.
authors.forename: X P
authors.initials: XP
authors.lastname: Yang
authors.affiliation: Department of Epidemiology, State Key Laboratory of Cardiovascular Disease, National Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
authors.forename: D F
authors.initials: DF
authors.lastname: Gu
mesh_terms: D000328:Adult; D044466:Asian People / Q000706:statistics & numerical data*; D015992:Body Mass Index; D002318:Cardiovascular Diseases / Q000208:ethnology; D002681:China / Q000453:epidemiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D015994:Incidence; D008297:Male; D009765:Obesity / Q000208:ethnology; D050177:Overweight / Q000208:ethnology*; D011446:Prospective Studies; D012306:Risk; D011795:Surveys and Questionnaires; D013851:Thinness / Q000208:ethnology*