title: Early Versus Late Cholecystectomy After Clearance of Common Bile Duct Stones by Endoscopic Retrograde Cholangiopancreatography: A Prospective Randomized Study.
abstract: BACKGROUND
  The time interval between endoscopic retrograde cholangiopancreatography (ERCP) and laparoscopic cholecystectomy (LC) is a matter of debate. This study was planned to compare early LC versus late LC.
  
  
  METHODS
  This is a prospective randomized study on patients who are presented with concomitant gallbladder and common bile duct stone. The study population was divided into two groups; group (A) managed by early LC within three days after ERCP; and group (B) managed by late LC one month after ERCP.
  
  
  RESULTS
  No significant difference between both groups as regards the conversion rate, the degree of adhesion, cystic duct diameter, and intraoperative common bile duct injury or bleeding. Recurrent biliary symptoms were significantly more in delayed LC group in 7 (12.71%) patient versus 1 patient in early LC (P=0.03).
  
  
  CONCLUSIONS
  No significant difference between both groups as regards the conversion rate. Recurrent biliary symptoms were significantly more in delayed LC while waiting LC. Morbidity was significantly more in delayed LC.
authors.affiliation: Department of General Surgery, Gastroenterology Surgical Center, Mansoura University, Mansoura, Egypt.
authors.forename: Ayman
authors.initials: A
authors.lastname: El Nakeeb
authors.forename: Helmy
authors.initials: H
authors.lastname: Ezzet
authors.forename: Waleed
authors.initials: W
authors.lastname: Askar
authors.forename: Ehab
authors.initials: E
authors.lastname: El Hanafy
authors.forename: Emad
authors.initials: E
authors.lastname: Hamdy
authors.forename: Ehab
authors.initials: E
authors.lastname: Atef
authors.forename: Mohamed
authors.initials: M
authors.lastname: Youssef
authors.forename: Hussein
authors.initials: H
authors.lastname: Talaat
authors.forename: Hosam
authors.initials: H
authors.lastname: Hamed
authors.forename: Talaat
authors.initials: T
authors.lastname: Abdallah
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D016063:Blood Loss, Surgical; D002760:Cholangiopancreatography, Endoscopic Retrograde / Q000379:methods*; D017081:Cholecystectomy, Laparoscopic / Q000379:methods*; D042883:Choledocholithiasis / Q000601:surgery*; D061887:Conversion to Open Surgery; D005260:Female; D042882:Gallstones / Q000601:surgery*; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D011182:Postoperative Care / Q000379:methods; D011446:Prospective Studies; D012008:Recurrence; D061665:Time-to-Treatment; D016896:Treatment Outcome; D055815:Young Adult