title: Higher Dental Caries Prevalence and Its Association with Dietary Habits and Physical Limitation in Epidermolysis Bullosa Patients: A Case Control Study.
abstract: OBJECTIVE
  Epidermolysis bullosa (EB) represents a highly rare subgroup of skin diseases that affects skin and mucous membrane. The aim of the present study was to assess caries prevalence and its associated factors in EB subjects. Salivary status was also assessed.
  
  
  METHODS
  Ten subjects with EB who were under supervision were selected (cases) and matched by age and gender with unaffected individuals (controls). Dental caries were recorded using the World Health Organization (WHO) criteria. Oral hygiene and dietary habits were investigated by clinical examination and questionnaires. Both nonstimulated and stimulated saliva were collected and salivary pH, buffering capacity and mouth opening were evaluated.
  
  
  RESULTS
  The results showed that the median decay-missing-filled teeth was significantly higher (p = 0.0094) in EB cases 5 (3.9-20.3) than in controls 3 (2-3.25). The groups also differed when food consistency was analyzed. Individuals with EB have a higher intake of soft food. In addition, the median mouth-opening values from cases (0.84-2.84 cm) and controls (4.3-4.9 cm) have shown to be statistically different (p = 0.007). Considering the salivary parameters, none of them showed significant differences among groups.
  
  
  CONCLUSIONS
  Epidermolysis bullosa subjects present higher caries scores and might be related to their physical condition and dietary habits.
  
  
  CONCLUSIONS
  There is a lack of information about oral status in EB subjects. Hence, our findings add useful information regarding the relationship between caries prevalence and associated risk factors in EB subjects.
authors.affiliation: Department of Dentistry, School of Health Sciences University of Brasília (UnB), Brasília-DF, Brazil.
authors.forename: Soraya Coelho
authors.initials: SC
authors.lastname: Leal
authors.affiliation: Professor Faculdade de Ciencias da Saude, Department of Dentistry, School of Health Sciences, Departamento de Odontologia, Universidade de Brasília (UnB) Campus Darcy Ribeiro, Brasília-DF 70910-900, Brazil, Phone: +556131071803 e-mail: ericalia@unb.br.
authors.forename: Erica Negrini
authors.initials: EN
authors.lastname: Lia
authors.affiliation: Department of Physical Medicine and Rehabilitation Spaulding Rehabilitation Hospital, Harvard Medical School Boston, Massachusetts, USA.
authors.forename: Rivadavio
authors.initials: R
authors.lastname: Amorim
authors.affiliation: Department of Dentistry, School of Health Sciences University of Brasília (UnB), Brasília-DF, Brazil.
authors.forename: Mateus Veppo
authors.initials: MV
authors.lastname: Dos Santos
authors.affiliation: Department of Dentistry, School of Health Sciences University of Brasília (UnB), Brasília-DF, Brazil.
authors.forename: Mayara Cundari
authors.initials: MC
authors.lastname: de Araújo
authors.affiliation: Department of Dental Materials and Prosthodontic, School of Dentistry, São Paulo State University (UNESP), São Paulo, Brazil.
authors.forename: Rodrigo Antônio
authors.initials: RA
authors.lastname: de Medeiros
authors.affiliation: Department of Dentistry, School of Health Sciences University of Brasília (UnB), Brasília-DF, Brazil.
authors.forename: Camila Abdanur
authors.initials: CA
authors.lastname: da Fonseca
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D003731:Dental Caries / Q000453:epidemiology*; D004820:Epidermolysis Bullosa / Q000150:complications / Q000503:physiopathology*; D005247:Feeding Behavior; D005260:Female; D005502:Food; D006801:Humans; D008297:Male; D009910:Oral Hygiene; D015995:Prevalence
keywords: Caries; Case control; Epidermolysis bullosa; Oral health; Saliva.