title: Deferasirox AUC efficacy cutoff and role of pharmacogenetics.
authors.affiliation: Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Unit of Infectious Diseases, Amedeo di Savoia Hospital University of TorinoCorso Svizzera 16410149 TurinItaly, University of Turin, 10149, Turin, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Allegra
authors.affiliation: Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Unit of Infectious Diseases, Amedeo di Savoia Hospital University of TorinoCorso Svizzera 16410149 TurinItaly, University of Turin, 10149, Turin, Italy.
authors.forename: J
authors.initials: J
authors.lastname: Cusato
authors.affiliation: Department of Biological and Clinical Sciences, S. Luigi Gonzaga Hospital, University of Turin, 10043, Orbassano, TO, Italy.
authors.forename: S
authors.initials: S
authors.lastname: De Francia
authors.affiliation: Department of Pediatrics, Centre for Microcitemie, S. Luigi Gonzaga Hospital, University of Turin, 10043, Orbassano, TO, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Massano
authors.affiliation: Department of Pediatrics, Centre for Microcitemie, S. Luigi Gonzaga Hospital, University of Turin, 10043, Orbassano, TO, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Piga
authors.affiliation: Laboratory of Clinical Pharmacology and Pharmacogenetics, Department of Medical Sciences, Unit of Infectious Diseases, Amedeo di Savoia Hospital University of TorinoCorso Svizzera 16410149 TurinItaly, University of Turin, 10149, Turin, Italy. antonio.davolio@unito.it.
authors.forename: A
authors.initials: A
authors.lastname: D'Avolio
mesh_terms: D019540:Area Under Curve; D001565:Benzoates / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D000077588:Deferasirox; D005260:Female; D005838:Genotype; D006801:Humans; D007502:Iron Chelating Agents / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D008297:Male; D010597:Pharmacogenetics; D020641:Polymorphism, Single Nucleotide; D016896:Treatment Outcome; D014230:Triazoles / Q000097:blood / Q000493:pharmacokinetics* / Q000627:therapeutic use*; D017086:beta-Thalassemia / Q000097:blood / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism
chemical_list: D001565:Benzoates; D007502:Iron Chelating Agents; D014230:Triazoles; D000077588:Deferasirox