title: [A sero-epidemiological study of hepatitis B among general population in Beijing].
abstract: OBJECTIVE
  To understand the sero-prevalence of hepatitis B in general population in Beijing and provide evidence for the prevention and control of hepatitis B.
  
  
  METHODS
  A serological survey was conducted in general population aged >1 year selected through multistage randomized cluster sampling in Beijing from August 2013 to February 2014. The estimated sample size was 5 200. Venous blood samples were collected from them to detect five hepatitis B serological indicators. The information about the hepatitis B immunization history and risk factors of the study subjects were collected through a questionnaire survey.
  
  
  RESULTS
  A total of 6 705 people were surveyed. The sero-positive rates of HBsAg, anti-HBs, anti-HBc and total HBV infection rate were 2.74%, 44.72%, 26.91% and 26.95% respectively. The age standardized rates were 2.73%, 44.83%, 26.84% and 26.87% respectively. As for the general population, in Beijing since the prevalence rate of hepatitis B surface antigen has decreased to 2.73%, <1% in children aged less than 5 years old, <1% in people aged less than 25 years old.
  
  
  CONCLUSIONS
  The integrated prevention and control strategy of hepatitis B had a significant effect in Beijing. We should continue to strengthen the work of adult hepatitis B vaccination.
authors.affiliation: Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: P
authors.initials: P
authors.lastname: Gao
authors.affiliation: Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: H
authors.initials: H
authors.lastname: Wang
authors.affiliation: Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: W X
authors.initials: WX
authors.lastname: Chen
authors.affiliation: Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: Y N
authors.initials: YN
authors.lastname: Sun
authors.affiliation: Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: W
authors.initials: W
authors.lastname: Zhang
authors.affiliation: Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: X H
authors.initials: XH
authors.lastname: Pang
authors.affiliation: Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: X
authors.initials: X
authors.lastname: He
authors.affiliation: Institute for Immunization of Beijing Municipal Center for Disease Control and Prevention, Beijing 100013, China.
authors.forename: J
authors.initials: J
authors.lastname: Wu
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000068476:Beijing / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D016021:Epidemiologic Studies; D006509:Hepatitis B / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology* / Q000276:immunology / Q000517:prevention & control; D006510:Hepatitis B Antibodies / Q000097:blood* / Q000276:immunology; D006514:Hepatitis B Surface Antigens / Q000276:immunology; D017325:Hepatitis B Vaccines / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D008875:Middle Aged; D011159:Population Surveillance / Q000379:methods; D015995:Prevalence; D012015:Reference Standards; D012307:Risk Factors; D018401:Sample Size; D013048:Specimen Handling; D011795:Surveys and Questionnaires; D014611:Vaccination / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: D006510:Hepatitis B Antibodies; D006514:Hepatitis B Surface Antigens; D017325:Hepatitis B Vaccines