title: Rapid Quantification of Trimethylamine.
abstract: Sensitive detection of trimethylamine both in aqueous and gaseous phases has been accomplished using an inexpensive colorimetric sensor array. Distinctive color change patterns provide facile discrimination over a wide range of concentrations for trimethylamine with >99% accuracy of classification. Calculated limits of detection are well below the diagnostically significant concentration for trimethylaminuria (fish malodor syndrome). The sensor array shows good reversibility after multiple uses and is able to cleanly discriminate trimethylamine from similar amine odorants. Portable sensing of trimethylamine vapors at ppb concentrations is described using a cell phone camera or a hand-held optoelectronic nose. Application of the sensor array in detecting mouth and skin odor as a potential tool for portable diagnosis of trimethylaminuria is also illustrated.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 S. Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Li
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 S. Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Hao
authors.initials: H
authors.lastname: Li
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 S. Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Maria K
authors.initials: MK
authors.lastname: LaGasse
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign , 600 S. Mathews Avenue, Urbana, Illinois 61801, United States.
authors.forename: Kenneth S
authors.initials: KS
authors.lastname: Suslick
mesh_terms: D003124:Colorimetry / Q000295:instrumentation; D008744:Methylamines / Q000032:analysis*; D013997:Time Factors
chemical_list: D008744:Methylamines; C023336:trimethylamine