title: Infectious Disease Report: Bordetella pertussis Infection in Patients With Cancer.
abstract: We illustrate 2 cases of pneumonia associated with Bordetella pertussis infection in 72-year-old and 61-year-old patients with cancer receiving myelosuppressive therapy after hematopoietic stem cell transplantation. Bacterial infections are a significant cause of morbidity and mortality in patients with cancer, and those receiving hematopoietic stem cell transplant, solid organ transplant, or myelosuppressive therapy are at increased risk. The infection was detected and the 2 patients had good outcomes following azithromycin treatment. Pertussis, also known as whooping cough, is a contagious respiratory illness that has become a public health challenge due to decreased immunity of the pertussis vaccine. Therefore, it is critical to recognize pertussis early in the course of the disease.
authors.affiliation: Department of Infectious Diseases, Moffitt Cancer Center, Tampa, FL 33612-9497, USA. John.Greene@Moffitt.org.
authors.forename: Abraham
authors.initials: A
authors.lastname: Yacoub
authors.forename: Sowmya
authors.initials: S
authors.lastname: Nanjappa
authors.forename: Tyler
authors.initials: T
authors.lastname: Janz
authors.forename: John N
authors.initials: JN
authors.lastname: Greene
mesh_terms: D000368:Aged; D001886:Bordetella pertussis / Q000472:pathogenicity*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*