title: [Extraocular muscles involvement in patients with thyroid-associated ophthalmopathy].
abstract: OBJECTIVE
  To study morphological features of extraocular muscles in patients with endocrine myopathy taking into account the duration of the disease.
  
  
  METHODS
  A total of 16 patients with thyroid eye disease were included in the study. After a routine ophthalmic examination, they all underwent extraocular muscle surgery and orbital decompression. The biopsy material obtained at surgery was studied histopathologically.
  
  
  RESULTS
  Particular morphological changes have been found in muscles of endocrine myopathy patients. Their relationship to disease duration has been also established.
  
  
  CONCLUSIONS
  Considering endocrine-related morphological changes in extraocular muscles, the favorable period for surgical correction has been defined.
authors.affiliation: Russian Medical Academy of Postgraduate Education, Ministry of Health of the Russian Federation, 2/1 Barrikadnaya St., Moscow, Russian Federation, 123995.
authors.forename: O D
authors.initials: OD
authors.lastname: Zhukova
authors.affiliation: S.P. Botkin State Clinical Hospital, Branch #1, Moscow Department of Public Health, 7 Mamonovskiy pereulok, Moscow, Russian Federation, 123001.
authors.forename: S Yu
authors.initials: SY
authors.lastname: Nechesnyuk
mesh_terms: D001706:Biopsy / Q000379:methods; D019299:Decompression, Surgical / Q000379:methods*; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D049970:Graves Ophthalmopathy / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D006801:Humans; D008297:Male; D008875:Middle Aged; D009801:Oculomotor Muscles / Q000473:pathology / Q000503:physiopathology / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome