title: Genomic Signatures of Speciation in Sympatric and Allopatric Hawaiian Picture-Winged Drosophila.
abstract: The Hawaiian archipelago provides a natural arena for understanding adaptive radiation and speciation. The Hawaiian Drosophila are one of the most diverse endemic groups in Hawaiì with up to 1,000 species. We sequenced and analyzed entire genomes of recently diverged species of Hawaiian picture-winged Drosophila, Drosophila silvestris and Drosophila heteroneura from Hawaiì Island, in comparison with Drosophila planitibia, their sister species from Maui, a neighboring island where a common ancestor of all three had likely occurred. Genome-wide single nucleotide polymorphism patterns suggest the more recent origin of D. silvestris and D. heteroneura, as well as a pervasive influence of positive selection on divergence of the three species, with the signatures of positive selection more prominent in sympatry than allopatry. Positively selected genes were significantly enriched for functional terms related to sensory detection and mating, suggesting that sexual selection played an important role in speciation of these species. In particular, sequence variation in Olfactory receptor and Gustatory receptor genes seems to play a major role in adaptive radiation in Hawaiian pictured-winged Drosophila.
authors.affiliation: Biocomplexity Institute, Virginia Tech, Blacksburg, Virginia.
authors.forename: Lin
authors.initials: L
authors.lastname: Kang
authors.affiliation: Biocomplexity Institute, Virginia Tech, Blacksburg, Virginia.
authors.forename: Robert
authors.initials: R
authors.lastname: Settlage
authors.affiliation: Howard Hughes Medical Institute, Johns Hopkins Medical Institutes, Baltimore, Maryland.
authors.forename: Wyatt
authors.initials: W
authors.lastname: McMahon
authors.affiliation: Biocomplexity Institute, Virginia Tech, Blacksburg, Virginia.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Michalak
authors.affiliation: Biocomplexity Institute, Virginia Tech, Blacksburg, Virginia.
authors.forename: Hongseok
authors.initials: H
authors.lastname: Tae
authors.affiliation: Primary Care Research Network and the Center for Bioinformatics and Genetics, Edward Via College of Osteopathic Medicine, Blacksburg, Virginia.
authors.forename: Harold R
authors.initials: HR
authors.lastname: Garner
authors.affiliation: Tropical Conservation Biology and Environmental Science Graduate Program, University of Hawaiì at Hilo.
authors.forename: Elizabeth A
authors.initials: EA
authors.lastname: Stacy
authors.affiliation: Tropical Conservation Biology and Environmental Science Graduate Program, University of Hawaiì at Hilo.
authors.forename: Donald K
authors.initials: DK
authors.lastname: Price
authors.affiliation: Biocomplexity Institute, Virginia Tech, Blacksburg, Virginia pawel@vbi.vt.edu.
authors.forename: Pawel
authors.initials: P
authors.lastname: Michalak
mesh_terms: D000818:Animals; D004330:Drosophila / Q000235:genetics*; D049810:Genetic Speciation; D014644:Genetic Variation; D005828:Genetics, Population; D049750:Genome, Insect; D006254:Hawaii; D059014:High-Throughput Nucleotide Sequencing; D010802:Phylogeny; D013045:Species Specificity
keywords: Hawaiian Drosophila; allopatry; genome analysis; speciation; sympatry