title: Clinical assessment of the specificity of an adipsin rapid test for the diagnosis of preeclampsia.
abstract: OBJECTIVE
  To evaluate the specificity of the adipsin rapid test in clinical practice for the diagnosis of preeclampsia (PE).
  
  
  METHODS
  A total of 1144 pregnant women were recruited in this study: 44 pregnant women with PE and 1100 healthy pregnancies as controls. Urine samples were collected and used, respectively, for the adipsin rapid test and the urinary dipstick test for protein detection. Sensitivity and specificity were calculated on the basis of the detection results.
  
  
  RESULTS
  In the 1144 women examined with the adipsin rapid test for PE diagnosis, the sensitivity and specificity were 93.2% and 98.8%, respectively; the total accuracy was 98.6%. For the 1144 women tested with urinary dipstick, the sensitivity and specificity were 93.2% and 40.5%, respectively; and the total accuracy was 42.5%.
  
  
  CONCLUSIONS
  Both the adipsin rapid test and the urinary dipstick test are noninvasive and inexpensive rapid tests for the diagnosis of PE. However, the adipsin rapid test was proven more reliable since it had a higher sensitivity, specificity, and accuracy.
authors.affiliation: a Department of Obstetrics and Gynecology , Laboratory of Molecular and Translational Medicine, Key Laboratory of Ministry of Education, West China Second University Hospital, Sichuan University , Sichuan , Chengdu , China.
authors.forename: Tao
authors.initials: T
authors.lastname: Wang
authors.affiliation: b Department of Obstetrics and Gynecology , Key Laboratory of Ministry of Education, West China Second University Hospital, Sichuan University , Sichuan , Chengdu , China.
authors.forename: Rong
authors.initials: R
authors.lastname: Zhou
authors.affiliation: a Department of Obstetrics and Gynecology , Laboratory of Molecular and Translational Medicine, Key Laboratory of Ministry of Education, West China Second University Hospital, Sichuan University , Sichuan , Chengdu , China.
authors.forename: Linbo
authors.initials: L
authors.lastname: Gao
authors.affiliation: a Department of Obstetrics and Gynecology , Laboratory of Molecular and Translational Medicine, Key Laboratory of Ministry of Education, West China Second University Hospital, Sichuan University , Sichuan , Chengdu , China.
authors.forename: Yanyun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: b Department of Obstetrics and Gynecology , Key Laboratory of Ministry of Education, West China Second University Hospital, Sichuan University , Sichuan , Chengdu , China.
authors.forename: Xinghui
authors.initials: X
authors.lastname: Liu
authors.affiliation: a Department of Obstetrics and Gynecology , Laboratory of Molecular and Translational Medicine, Key Laboratory of Ministry of Education, West China Second University Hospital, Sichuan University , Sichuan , Chengdu , China.
authors.forename: Lin
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D011416:Complement Factor D / Q000652:urine*; D005260:Female; D006801:Humans; D007118:Immunoassay; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000652:urine; D011247:Pregnancy; D011507:Proteinuria / Q000652:urine; D012680:Sensitivity and Specificity; D055815:Young Adult
chemical_list: D011416:Complement Factor D
keywords: Adipsin; adipsin rapid test; preeclampsia; specificity; urine dipstick