title: Antisynthetase syndrome: a case report.
abstract: The case is about a 48-year-old man with one week history of progressively worsening shortness of breath and reduced exercise tolerance. Laboratory investigations revealed raised ESR, creatine kinase (CK) and positive anti-aminoacyl-transfer RNA synthetase. High resolution computed tomography (HRCT) chest showed prominent mediastinal lymph nodes and scattered lung nodules. These findings along with clinical features and investigations confirmed the diagnosis of antisynthetase syndrome (ASS). The radiological investigations proved to be the key step in diagnosis and management of this case.
authors.affiliation: 1 Registrar General Practice, Westmidlands, UK ; 2 Consutlant Radiologist, 3 Respiratory Physicians, Good Hope Hospital, Birmingham, UK.
authors.forename: Mehwish Asif
authors.initials: MA
authors.lastname: Qureshi
authors.affiliation: 1 Registrar General Practice, Westmidlands, UK ; 2 Consutlant Radiologist, 3 Respiratory Physicians, Good Hope Hospital, Birmingham, UK.
authors.forename: Edward
authors.initials: E
authors.lastname: Hoey
authors.affiliation: 1 Registrar General Practice, Westmidlands, UK ; 2 Consutlant Radiologist, 3 Respiratory Physicians, Good Hope Hospital, Birmingham, UK.
authors.forename: Timothy
authors.initials: T
authors.lastname: Fletcher
authors.affiliation: 1 Registrar General Practice, Westmidlands, UK ; 2 Consutlant Radiologist, 3 Respiratory Physicians, Good Hope Hospital, Birmingham, UK.
authors.forename: Zubair
authors.initials: Z
authors.lastname: Ahmed
keywords: Antisynthetase syndrome (ASS); high resolution computed tomography (HRCT); interstitial lund disease (ILD)