title: Prospective Analysis of Primary Breast Augmentation on Body Image Using the BREAST-Q: Results from a Nationwide Study.
abstract: BACKGROUND
  The Breast Implant Follow-up Study is a large, ongoing observational study of women who received Natrelle round silicone-filled or saline-filled breast implants. This analysis describes patient-reported outcomes in the cohort who underwent breast augmentation.
  
  
  METHODS
  Subjects prospectively completed two validated scales of the BREAST-Q (satisfaction with breasts and psychosocial well-being) preoperatively and at 1 and 4 years postoperatively. Effect size and z tests were used to compare differences between preoperative versus postoperative scores; multivariate mixed models were used to compare differences in scores between silicone-filled and saline-filled implants.
  
  
  RESULTS
  Of 17,899 subjects completing the BREAST-Q preoperatively, 14,514 (81.1 percent) completed the postoperative questionnaire (12,726 received silicone-filled implants and 1788 received saline-filled implants). Overall, satisfaction with breasts and psychosocial well-being increased significantly at postoperative year 1 (p < 0.0001 for both), and the improvement was sustained at year 4 (p < 0.0001 for both). Large effect sizes were observed for satisfaction with breasts (2.0 at year 1; 1.8 at year 4) and psychosocial well-being (1.2 at year 1; 1.0 at year 4). In the multivariate model, silicone-filled implants were associated with significantly greater improvement compared with saline-filled implants for satisfaction with breasts and psychosocial well-being at year 1 (p < 0.0001 for both) and year 4 (p < 0.0001 and p < 0.0019, respectively).
  
  
  CONCLUSIONS
  Breast implants are effective in improving women's quality of life. The authors found significant and sustained improvements in satisfaction and psychosocial well-being in women undergoing breast augmentation with Natrelle silicone-filled or saline-filled implants.
  
  
  METHODS
  Therapeutic, IV.
authors.affiliation: Alpharetta, Ga.; New York, N.Y.; and Irvine, Calif.|From the Swan Center for Plastic Surgery; Memorial Sloan Kettering Cancer Center; and Allergan, Inc.
authors.forename: Amy
authors.initials: A
authors.lastname: Alderman
authors.affiliation: Alpharetta, Ga.; New York, N.Y.; and Irvine, Calif.|From the Swan Center for Plastic Surgery; Memorial Sloan Kettering Cancer Center; and Allergan, Inc.
authors.forename: Andrea
authors.initials: A
authors.lastname: Pusic
authors.affiliation: Alpharetta, Ga.; New York, N.Y.; and Irvine, Calif.|From the Swan Center for Plastic Surgery; Memorial Sloan Kettering Cancer Center; and Allergan, Inc.
authors.forename: Diane K
authors.initials: DK
authors.lastname: Murphy
mesh_terms: D000328:Adult; D000368:Aged; D001828:Body Image; D018427:Breast Implants; D015331:Cohort Studies; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys; D006801:Humans; D016462:Mammaplasty / Q000379:methods* / Q000523:psychology*; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life / Q000523:psychology; D012828:Silicones; D012965:Sodium Chloride; D011795:Surveys and Questionnaires; D055815:Young Adult
chemical_list: D012828:Silicones; D012965:Sodium Chloride