title: Severe Acute Pulmonary Toxicity Associated with Brentuximab in a Patient with Refractory Hodgkin's Lymphoma.
abstract: Acute pulmonary toxicity associated with brentuximab appears to be a rare but serious adverse effect that can be potentially fatal. We report the case of a twenty-nine-year-old female with Hodgkin's lymphoma who was treated with brentuximab and later presented with severe acute pulmonary toxicity; she improved after the discontinuation of brentuximab and administration of antibiotics and glucocorticoid therapy. Currently there is very little data in the literature in regard to the clinical manifestations and characteristics of patients taking brentuximab and the potential development of acute severe pulmonary toxicity, as well as the appropriate therapeutic approach, making this particular case of successful treatment and resolution unique.
authors.affiliation: Division of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
authors.forename: Yasmin
authors.initials: Y
authors.lastname: Sabet
authors.affiliation: Division of Medical Education, Paul L. Foster School of Medicine and Texas Tech University HSC, El Paso, TX 79905, USA.
authors.forename: Saul
authors.initials: S
authors.lastname: Ramirez
authors.affiliation: Division of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Rosell Cespedes
authors.affiliation: Division of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
authors.forename: Marimer
authors.initials: M
authors.lastname: Rensoli Velasquez
authors.affiliation: School of Medicine, Universidad Autonoma de Tamaulipas (UAT), Tampico, Mexico.
authors.forename: Mateo
authors.initials: M
authors.lastname: Porres-Muñoz
authors.affiliation: Division of Hematology and Oncology, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
authors.forename: Sumit
authors.initials: S
authors.lastname: Gaur
authors.affiliation: Division of Pulmonary and Critical Care Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
authors.forename: Juan B
authors.initials: JB
authors.lastname: Figueroa-Casas
authors.affiliation: Division of General Internal Medicine, Texas Tech University Health Sciences Center, El Paso, TX 79905, USA.
authors.forename: Mateo
authors.initials: M
authors.lastname: Porres-Aguilar