title: Normative reference values of thoracic aortic diameter in American College of Radiology Imaging Network (ACRIN 6654) arm of National Lung Screening Trial.
abstract: OBJECTIVE
  This study aims to establish normative reference values for thoracic aortic diameter (AD) in participants in the National Lung Screening Trial.
  
  
  METHODS
  Thoracic AD on 322 prevalence computed tomography was recorded at the sinotubular junction, mid-ascending, transverse arch, mid-descending, and diaphragmatic hiatus.
  
  
  RESULTS
  Mean AD (cm) and upper limits of normal for men and women were recorded for at each location. Smoking did not correlate with AD. Age, gender, and body surface area (BSA) were the most significant factors.
  
  
  CONCLUSIONS
  Thoracic AD reference values are reported. They do not correlate with smoking, but they did for age, gender, and BSA.
authors.affiliation: Department of Radiology, Mayo Clinic Florida, 4500 San Pablo Road, Jacksonville, FL, 32224. Electronic address: mccomb.barbara@mayo.edu.
authors.forename: Barbara L
authors.initials: BL
authors.lastname: McComb
authors.affiliation: Houston Methodist Hospital and Research Institute, Houston, TX, 77030. Electronic address: rfmunden@houstonmethodist.org.
authors.forename: Reginald F
authors.initials: RF
authors.lastname: Munden
authors.affiliation: Department of Biostatistics and Center for Statistical Sciences, Brown University School of Public Health, Box G-S121-7, 121 S. Main Street, Providence, RI, 02912. Electronic address: fduan@stat.brown.edu.
authors.forename: Fenghai
authors.initials: F
authors.lastname: Duan
authors.affiliation: Department of Biostatistics and Center for Statistical Sciences, Brown University School of Public Health, Box G-S121-7, 121 S. Main Street, Providence, RI, 02912. Electronic address: amanda.m.jain@gmail.com.
authors.forename: Amanda A
authors.initials: AA
authors.lastname: Jain
authors.affiliation: Fox Chase Cancer Center, 333 Cottman Avenue, Philadelphia, PA, 19111. Electronic address: ctuite@fccc.edu.
authors.forename: Catherine
authors.initials: C
authors.lastname: Tuite
authors.affiliation: Department of Radiology, Wake Forest Health Sciences Center, Medical Center Boulevard, Winston-Salem, NC, 27157. Electronic address: cchiles@wakehealth.edu.
authors.forename: Caroline
authors.initials: C
authors.lastname: Chiles
mesh_terms: D000368:Aged; D001013:Aorta, Thoracic / Q000033:anatomy & histology* / Q000000981:diagnostic imaging; D001830:Body Surface Area; D003195:Computer Communication Networks; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000517:prevention & control; D008297:Male; D008875:Middle Aged; D016032:Randomized Controlled Trials as Topic; D012016:Reference Values; D014057:Tomography, X-Ray Computed; D014481:United States
keywords: Aorta; NLST; aortic aneurysm; screening CT