title: Survey of Attitudes toward Uterus Transplantation among Japanese Women of Reproductive Age: A Cross-Sectional Study.
abstract: OBJECTIVE
  Uterus transplantation (UTx) is a potential option for women with uterine factor infertility to have a child, but there has been no large-scale survey of the views on UTx in women of reproductive age in Japan. The present study was aimed to clarify the views of Japanese women of reproductive age on UTx for uterine factor infertility.
  
  
  METHODS
  A questionnaire on UTx was conducted by an Internet research company in December 2014 as a cross-sectional study in 3,892 randomly chosen women aged 25 to 39 years old. Responses were analyzed from 3,098 subjects (mean age 32.1±4.2 years old), after exclusion of inappropriate respondents in screening.
  
  
  RESULTS
  Of the respondents, 62.1%, 34.7% and 18.1% favored adoption, UTx and gestational surrogacy, respectively. In contrast, 7.0%, 21.9% and 63.3% opposed adoption, UTx and gestational surrogacy, respectively. In choices of candidates for UTx based on highest priority, deceased persons (33.8%) and mothers (19.0%) were favored as donors, and women with congenital absence of the uterus (54.4%) and hysterectomy due to a malignant uterine tumor (20.0%) as recipients. Regarding societal acceptance of UTx, the answer rates were 15.7% for "UTx should be permitted", 77.6% for "UTx should be permitted with discussion", and 6.7% for "UTx should not be permitted, even with discussion". Regarding personal opinions on UTx, 44.2% were in favor, 47.5% had no opinion, and 8.3% were against.
  
  
  CONCLUSIONS
  Our results suggest that many Japanese women of reproductive age feel that UTx is socially and individually acceptable, but that concerns requiring further discussion remain among these women. There was also a tendency for UTx to be viewed more favorably than gestational surrogacy.
authors.affiliation: Department of Obstetrics and Gynecology, Keio University, School of Medicine, Tokyo, Japan.
authors.forename: Iori
authors.initials: I
authors.lastname: Kisu
authors.affiliation: Department of Obstetrics and Gynecology, Keio University, School of Medicine, Tokyo, Japan.
authors.forename: Kouji
authors.initials: K
authors.lastname: Banno
authors.affiliation: Faculty of Nursing and Medical Care, Keio University, Tokyo, Japan.
authors.forename: Etsuko
authors.initials: E
authors.lastname: Soeda
authors.affiliation: Department of Nursing, Keio University Hospital, Tokyo, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kurihara
authors.affiliation: Department of Nursing, Keio University Hospital, Tokyo, Japan.
authors.forename: Miho
authors.initials: M
authors.lastname: Okushima
authors.affiliation: Department of Nursing, Keio University Hospital, Tokyo, Japan.
authors.forename: Ami
authors.initials: A
authors.lastname: Yamaguchi
authors.affiliation: Department of Nursing, Keio University Hospital, Tokyo, Japan.
authors.forename: Eriko
authors.initials: E
authors.lastname: Nakagawa
authors.affiliation: Department of Obstetrics and Gynecology, Keio University, School of Medicine, Tokyo, Japan.
authors.forename: Kiyoko
authors.initials: K
authors.lastname: Umene
authors.affiliation: Department of Obstetrics and Gynecology, Keio University, School of Medicine, Tokyo, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Aoki
mesh_terms: D000328:Adult; D044466:Asian People / Q000523:psychology; D001290:Attitude; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D011795:Surveys and Questionnaires; D014599:Uterus / Q000637:transplantation*; D055815:Young Adult