title: Inhibition of precursor B-cell malignancy progression by toll-like receptor ligand-induced immune responses.
authors.affiliation: Michael Cuccione Childhood Cancer Research Program, Child and Family Research Institute, Vancouver, British Columbia, Canada.
authors.forename: M
authors.initials: M
authors.lastname: Fidanza
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Department of Pediatrics, Division of Oncology, University of Pennsylvania, Philadelphia, PA, USA.|Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: A E
authors.initials: AE
authors.lastname: Seif
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA.|Department of Pathology and Laboratory Medicine, Division of Cancer Pathobiology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: A
authors.initials: A
authors.lastname: DeMicco
authors.affiliation: Michael Cuccione Childhood Cancer Research Program, Child and Family Research Institute, Vancouver, British Columbia, Canada.|Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: N
authors.initials: N
authors.lastname: Rolf
authors.affiliation: Michael Cuccione Childhood Cancer Research Program, Child and Family Research Institute, Vancouver, British Columbia, Canada.
authors.forename: S
authors.initials: S
authors.lastname: Jo
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA.|Department of Pathology and Laboratory Medicine, Division of Cancer Pathobiology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: B
authors.initials: B
authors.lastname: Yin
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Department of Pediatrics, Division of Oncology, University of Pennsylvania, Philadelphia, PA, USA.|Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Li
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Department of Pediatrics, Division of Oncology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: D M
authors.initials: DM
authors.lastname: Barrett
authors.affiliation: Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
authors.forename: J
authors.initials: J
authors.lastname: Duque-Afonso
authors.affiliation: Department of Pathology, School of Medicine, Stanford University, Stanford, CA, USA.
authors.forename: M L
authors.initials: ML
authors.lastname: Cleary
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA.|Department of Pathology and Laboratory Medicine, Division of Cancer Pathobiology, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: C H
authors.initials: CH
authors.lastname: Bassing
authors.affiliation: Center for Childhood Cancer Research, The Children's Hospital of Philadelphia, Philadelphia, PA, USA.|Department of Pediatrics, Division of Oncology, University of Pennsylvania, Philadelphia, PA, USA.|Abramson Family Cancer Research Institute, University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: S A
authors.initials: SA
authors.lastname: Grupp
authors.affiliation: Michael Cuccione Childhood Cancer Research Program, Child and Family Research Institute, Vancouver, British Columbia, Canada.|Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada.
authors.forename: G S D
authors.initials: GS
authors.lastname: Reid
mesh_terms: D000818:Animals; D051792:Basic Helix-Loop-Helix Proteins / Q000235:genetics; D050676:Core Binding Factor Alpha 2 Subunit / Q000378:metabolism; D018450:Disease Progression; D015973:Gene Expression Regulation, Leukemic; D006801:Humans; D007107:Immune System; D007249:Inflammation; D008024:Ligands; D051379:Mice; D008822:Mice, Transgenic; D009500:Neutralization Tests; D051757:PAX5 Transcription Factor / Q000378:metabolism; D010641:Phenotype; D000075062:Pre-B-Cell Leukemia Transcription Factor 1 / Q000235:genetics; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000276:immunology* / Q000378:metabolism*; D054448:Precursor Cells, B-Lymphoid / Q000276:immunology / Q000378:metabolism*; D050783:Proto-Oncogene Proteins c-ets / Q000378:metabolism; D012097:Repressor Proteins / Q000378:metabolism; D051193:Toll-Like Receptors / Q000378:metabolism*; D000097764:ETS Translocation Variant 6 Protein
chemical_list: D051792:Basic Helix-Loop-Helix Proteins; D050676:Core Binding Factor Alpha 2 Subunit; D008024:Ligands; D051757:PAX5 Transcription Factor; D000075062:Pre-B-Cell Leukemia Transcription Factor 1; D050783:Proto-Oncogene Proteins c-ets; D012097:Repressor Proteins; D051193:Toll-Like Receptors; D000097764:ETS Translocation Variant 6 Protein; C497282:Pax5 protein, mouse; C481797:Pbx1 protein, mouse; C493726:Runx1 protein, mouse; C075668:Tcf3 protein, mouse