title: Prospective multicenter surveillance identifies Staphylococcus aureus infections caused by livestock-associated strains in an agricultural state.
abstract: We conducted a surveillance study to investigate the epidemiology of Staphylococcus aureus infections in Iowa, using a convenience sample. Diagnostic laboratories submitted 20 S. aureus isolates per month for a 20-month period between 2011 and 2013. Of the 2226 isolates analyzed, 73.6% were methicillin-resistant S. aureus (MRSA) and 26.4% were methicillin-susceptible S. aureus (MSSA). S. aureus infections in 25 patients (1%) were caused by ST398- and ST9-associated strain types, and appeared to be a common occurrence in areas of the state with the highest numbers of hogs and hog farms. Twenty nine (5.1%) of MSSA isolates and 10 (40.0%) livestock-associated strains were multi-drug resistant.
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: Rajeshwari
authors.initials: R
authors.lastname: Nair
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: James
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA; Department of Geographical & Sustainability Sciences, University of Iowa College of Liberal Arts & Sciences, Iowa City, IA.
authors.forename: Margaret
authors.initials: M
authors.lastname: Carrel
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: Ashley
authors.initials: A
authors.lastname: O'Brien
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: Megan
authors.initials: M
authors.lastname: Quick
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: Sarah
authors.initials: S
authors.lastname: Farina
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA.
authors.forename: Shylo
authors.initials: S
authors.lastname: Wardyn
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA; Department of Biostatistics, Environmental Health Sciences & Epidemiology, College of Public Health, Kent State University, Kent, OH.
authors.forename: Dipendra
authors.initials: D
authors.lastname: Thapaliya
authors.affiliation: Department of Biostatistics, Environmental Health Sciences & Epidemiology, College of Public Health, Kent State University, Kent, OH.
authors.forename: Dylan
authors.initials: D
authors.lastname: Grenier
authors.affiliation: Center for Emerging Infectious Diseases, University of Iowa College of Public Health, Iowa City, IA; Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA; Department of Biostatistics, Environmental Health Sciences & Epidemiology, College of Public Health, Kent State University, Kent, OH. Electronic address: tsmit176@kent.edu.
authors.forename: Tara C
authors.initials: TC
authors.lastname: Smith
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000818:Animals; D062665:Epidemiological Monitoring; D005260:Female; D005838:Genotype; D006801:Humans; D007484:Iowa / Q000453:epidemiology; D058751:Livestock; D008297:Male; D017720:Molecular Epidemiology; D058889:Molecular Typing; D016273:Occupational Exposure; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology* / Q000635:transmission; D013211:Staphylococcus aureus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification; D015047:Zoonoses / Q000635:transmission
keywords: Infection; Livestock; Methicillin resistant; Methicillin susceptible; Staphylococcus aureus; Surveillance