title: Contemporary management of ductal carcinoma in situ and lobular carcinoma in situ.
abstract: The management of in situ lesions ductal carcinoma in situ (DCIS) and lobular carcinoma in situ (LCIS) continues to evolve. These diagnoses now comprise a large burden of mammographically diagnosed cancers, and with a global trend towards more population-based screening, the incidence of these lesions will continue to rise. Because outcomes following treatment for DCIS and LCIS are excellent, there is emerging controversy about what extent of treatment is optimal for both diseases. Here we review the current approaches to the diagnosis and treatment of both DCIS and LCIS. In addition, we will consider potential directions for future management of these lesions.
authors.affiliation: Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: Samilia
authors.initials: S
authors.lastname: Obeng-Gyasi
authors.affiliation: Duke University Medical Center, Durham, NC 27710, USA.
authors.forename: Cecilia
authors.initials: C
authors.lastname: Ong
authors.affiliation: Duke University Medical Center, Durham, NC 27710, USA. shelley.hwang@duke.edu.
authors.forename: E Shelley
authors.initials: ES
authors.lastname: Hwang
mesh_terms: D001943:Breast Neoplasms / Q000473:pathology / Q000628:therapy*; D002278:Carcinoma in Situ / Q000473:pathology / Q000628:therapy*; D044584:Carcinoma, Ductal / Q000473:pathology / Q000628:therapy*; D018275:Carcinoma, Lobular / Q000473:pathology / Q000628:therapy*; D019468:Disease Management; D005260:Female; D006801:Humans
keywords: Ductal carcinoma in situ (DCIS); lobular carcinoma in situ (LCIS); lobular neoplasia (LN)