title: A randomized controlled trial of self-regulated modified constraint-induced movement therapy in sub-acute stroke patients.
abstract: Emerging research suggests the use of self-regulation (SR) for improving functional regain in patients post stroke. SR is proposed to produce an added effect to effective modified constraint-induced movement therapy (mCIMT). This study aimed to examine the effect of a self-regulated mCIMT programme (SR-mCIMT) for functional regain in patients with sub-acute stroke.
  
  
  
  Eighty-six patients completed the trial: SR-mCIMT, n = 29; mCIMT, n = 31; or conventional functional rehabilitation, n = 26. All interventions were 2-week therapist-guided training. Outcome measurements, taken by a blinded assessor, examined arm function [Action Research Arm Test (ARAT), Fugl-Meyer Assessment (FMA)], daily task performance [Lawton Instrumental Activities of Daily Living Scale (Lawton IADL)] and self-perceived arm use in functional tasks [Motor Activity Log (MAL)].
  
  
  
  Significant differences were found with the SR-mCIMT outperforming the other groups after the intervention (ARAT, P = 0.006; FMA, Lawton IADL and MAL, all Ps < 0.001). In terms of the carry-over effect, the SR-mCIMT group outperformed in the hand and coordination subscales of ARAT and FMA (P = 0.012-0.013) and the self-perceived quality of arm use (P = 0.002).
  
  
  
  A combination of SR and mCIMT could produce an added effect in functional regain in patients post stroke.
authors.affiliation: Western Sydney University, Penrith, NSW, Australia.
authors.forename: K P Y
authors.initials: KP
authors.lastname: Liu
authors.affiliation: Concord Hopsital, Concord, NSW, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Balderi
authors.affiliation: Hong Kong Hospital Authority, Hong Kong, China.
authors.forename: T L F
authors.initials: TL
authors.lastname: Leung
authors.affiliation: Hong Kong Hospital Authority, Hong Kong, China.
authors.forename: A S Y
authors.initials: AS
authors.lastname: Yue
authors.affiliation: Recovre, Sydney, NSW, Australia.
authors.forename: N C W
authors.initials: NC
authors.lastname: Lam
authors.affiliation: Hong Kong Hospital Authority, Hong Kong, China.
authors.forename: J T Y
authors.initials: JT
authors.lastname: Cheung
authors.affiliation: The University of Hong Kong, Hong Kong, China.
authors.forename: S S M
authors.initials: SS
authors.lastname: Fong
authors.affiliation: Hong Kong Hospital Authority, Hong Kong, China.
authors.forename: C M W
authors.initials: CM
authors.lastname: Sum
authors.affiliation: Griffith University, Gold Coast, Qld, Australia.
authors.forename: M
authors.initials: M
authors.lastname: Bissett
authors.affiliation: Western Sydney University, Penrith, NSW, Australia.
authors.forename: R
authors.initials: R
authors.lastname: Rye
authors.affiliation: The Chinese University of Hong Kong, Hong Kong, China.
authors.forename: V C T
authors.initials: VC
authors.lastname: Mok
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D026741:Physical Therapy Modalities; D020127:Recovery of Function / Q000502:physiology; D000068356:Self-Control; D020521:Stroke / Q000503:physiopathology*; D000071939:Stroke Rehabilitation; D016896:Treatment Outcome
keywords: functional recovery; modified constraint-induced movement therapy; randomized controlled trial; self-regulation; stroke