title: Cytokine-producing function of human blood cells in chronic atrophic gastritis and gastric adenomas and adenocarcinomas.
abstract: The cytokine-producing potential of blood cells has been studied in the atrophic gastritis-adenoma-adenocarcinoma progression of pathological states of the stomach. It has been revealed that, at the initial stage of carcinogenesis, namely adenoma, immunocompetent cells have the highest cytokine-producing proto-oncogenic potential as compared to both atrophic gastritis, which presents a precancerous condition, and completely formed malignant tumor (gastric adenocarcinoma).
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia. avsosnina@yandex.ru.
authors.forename: A V
authors.initials: AV
authors.lastname: Sosnina
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia.
authors.forename: A I
authors.initials: AI
authors.lastname: Autenshlyus
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia.
authors.forename: E S
authors.initials: ES
authors.lastname: Mikhailova
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia.
authors.forename: D V
authors.initials: DV
authors.lastname: Morozov
authors.affiliation: Novosibirsk State Medical University, Novosibirsk, 630091, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Vankhalsky
authors.affiliation: Novosibirsk State Medical University, Novosibirsk, 630091, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Shpagina
authors.affiliation: Vektor-Best, Koltsovo, Novosibirsk oblast, 630559, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Varaksin
authors.affiliation: Research Institute of Molecular Biology and Biophysics, Siberian Branch, Russian Academy of Medical Sciences, Novosibirsk, 630117, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Lyakhovich
mesh_terms: D000230:Adenocarcinoma / Q000097:blood*; D000236:Adenoma / Q000097:blood*; D016207:Cytokines / Q000097:blood*; D005260:Female; D005757:Gastritis, Atrophic / Q000097:blood*; D006801:Humans; D007962:Leukocytes / Q000378:metabolism*; D008297:Male; D009363:Neoplasm Proteins / Q000097:blood*; D013274:Stomach Neoplasms / Q000097:blood*
chemical_list: D016207:Cytokines; D009363:Neoplasm Proteins