title: Cervical Cancer Histology, Staging and Survival before and after Implementation of Organised Cervical Screening Programme in Poland.
abstract: A population-based organised cervical cancer screening programme (OCCSP) was introduced in Poland in 2006. In this study we have aimed to analyse whether selected parameters related to invasive cervical cancer (ICC) of patients diagnosed in two distant gynaecological oncology centres changed after the first screening round of the programme run between 2006-2008. We have run a retrospective cross-sectional analysis of 189 women diagnosed with ICC between 2002-2005 (directly before introduction of the programme) and 165 patients diagnosed between 2009-2012 (just after the first screening round of the programme) and compared their age at diagnosis, histology, stage of tumours and overall survival (OS). Mean age of patients diagnosed in years 2002-2005 and 2009-2012 was 52.1 and 52.6 years respectively. Squamous cell carcinomas constituted 90.5% and 86.1% of tumours diagnosed in years 2002-2005 and 2009-2012 respectively and the rest of tumours had glandular and other histologies. 74.5% and 61.0% of women diagnosed in years 2002-2005 and 2009-2012 respectively had early ICC (FIGO-International Federation of Gynaecology and Obstetrics stages I-IIA) and the rest had advanced disease (FIGO IIB-IV). We have noticed no significant differences in mean age of patients, histology of tumours and OS of patients with ICC diagnosed before and after the first screening round of OCSSP in Poland. Advanced stages of ICC were more commonly diagnosed after the introduction of OCSSP. Changes only in some clinical parameters of patients with ICC were noticed before and after the first screening round of OCSSP in Poland but OS of patients remained the same.
authors.affiliation: Department of Gynaecology and Oncological Gynaecology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Nowakowski
authors.affiliation: Department of Biochemistry and Molecular Biology, Medical University of Lublin, Lublin, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Cybulski
authors.affiliation: Department of Gynaecology and Oncological Gynaecology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Irmina
authors.initials: I
authors.lastname: Buda
authors.affiliation: Department of Obstetrics, Gynaecology and Oncological Gynaecology, Medical University of Silesia, Bytom, Poland.
authors.forename: Iwona
authors.initials: I
authors.lastname: Janosz
authors.affiliation: Department of Obstetrics, Gynaecology and Oncological Gynaecology, Medical University of Silesia, Bytom, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Olszak-Wąsik
authors.affiliation: Department of Obstetrics, Gynaecology and Oncological Gynaecology, Medical University of Silesia, Bytom, Poland.
authors.forename: Piotr
authors.initials: P
authors.lastname: Bodzek
authors.affiliation: National Health Fund, Central Office, Warsaw, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Śliwczyński
authors.affiliation: National Health Fund, Central Office, Warsaw, Poland.
authors.forename: Zbigniew
authors.initials: Z
authors.lastname: Teter
authors.affiliation: Department of Obstetrics, Gynaecology and Oncological Gynaecology, Medical University of Silesia, Bytom, Poland.
authors.forename: Anita
authors.initials: A
authors.lastname: Olejek
authors.affiliation: Department of Gynaecology and Oncological Gynaecology, Military Institute of Medicine, Warsaw, Poland.
authors.forename: Włodzimierz
authors.initials: W
authors.lastname: Baranowski
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000401:mortality / Q000473:pathology; D003430:Cross-Sectional Studies; D055088:Early Detection of Cancer; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D015999:Multivariate Analysis; D009367:Neoplasm Staging / Q000379:methods*; D011044:Poland / Q000453:epidemiology; D012189:Retrospective Studies; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000401:mortality* / Q000473:pathology*