title: The Association of Job Strain With Medication Adherence: Is Your Job Affecting Your Compliance With a Prescribed Medication Regimen?
abstract: This innovative study examines for the first time the relationship between occupational factors (eg, job strain) and medication adherence.
  
  
  
  An analysis of secondary data collected from a randomized controlled trial (RCT) implemented in 34 drugstores of a national pharmacy chain in Tennessee. Medication adherence, health care utilization, psychosocial assessment, chronic disease status, and occupational health history data were obtained from study participants.
  
  
  
  The study found that most job strains are less adherent to their medication regimen as measured by proportion of days covered (PDC) than those in a low strain job category. However, statistically significant differences are observed only for renin angiotensin system antagonists (RASA), statins, and when PDC is combined across all medication classes.
  
  
  
  Examining occupational factors may prove beneficial in developing interventions that improve medication adherence.
authors.affiliation: Department of Pharmacy and Therapeutics, School of Pharmacy, University of Pittsburgh (Drs Kearney and Pringle); Behavioral Health Economics Program, RTI International, North Carolina (Dr Aldridge); Department of Health Policy and Management (Dr Castle), and Department of Environmental and Occupational Health, Graduate School of Public Health, University of Pittsburgh (Dr Peterson), Pennsylvania.
authors.forename: Shannon M
authors.initials: SM
authors.lastname: Kearney
authors.forename: Arnie P
authors.initials: AP
authors.lastname: Aldridge
authors.forename: Nicholas G
authors.initials: NG
authors.lastname: Castle
authors.forename: James
authors.initials: J
authors.lastname: Peterson
authors.forename: Janice L
authors.initials: JL
authors.lastname: Pringle
mesh_terms: D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000453:epidemiology; D002908:Chronic Disease / Q000453:epidemiology; D003920:Diabetes Mellitus / Q000188:drug therapy / Q000453:epidemiology; D005260:Female; D006801:Humans; D008297:Male; D055118:Medication Adherence; D008875:Middle Aged; D015233:Models, Statistical; D000073397:Occupational Stress / Q000453:epidemiology*; D010593:Pharmaceutical Services; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D013714:Tennessee / Q000453:epidemiology