title: [Acute intestinal obstruction revealing enteropathy associated t-cell lymphoma, about a case].
abstract: Enteropathy associated T-cell lymphoma (EATL) is a rare complication of celiac disease (CD). We report a case of EATL associated with CD revealed by acute intestinal obstruction. A North African woman of 38 years old with a history of infertility and chronic abdominal pain was admitted in emergency with acute intestinal obstruction. During the surgery, we found a tumor on the small intestine with mesenteric lymphadenopathy. Histology and immunohistochemistry of the specimen objectified a digestive T lymphoma CD3+ and immunological assessment of celiac disease was positive. The diagnosis of EATL was thus retained. Chemotherapy (CHOEP protocol) was established as well as gluten-free diet with a complete response to treatment. The EATL is a rare complication of CD that can be revealed by intestinal obstruction. The prognosis can be improved by early treatment involving surgery and chemotherapy. Its prevention requires early diagnosis of celiac and gluten-free diets.
authors.affiliation: Service de Médecine Interne et Générale, Hôpital National de Zinder, Niger.
authors.forename: Abdoul Aziz
authors.initials: AA
authors.lastname: Garba
authors.affiliation: Service de Chirurgie Générale et Digestive B, Hôpital National de Zinder, Niger.
authors.forename: Harissou
authors.initials: H
authors.lastname: Adamou
authors.affiliation: Service de Chirurgie Générale et Digestive B, Hôpital National de Zinder, Niger.
authors.forename: Ibrahim Amadou
authors.initials: IA
authors.lastname: Magagi
authors.affiliation: Service de Médecine Interne et Générale, Hôpital National de Niamey, Niger.
authors.forename: Souleymane
authors.initials: S
authors.lastname: Brah
authors.affiliation: Service de Chirurgie Générale et Digestive B, Hôpital National de Zinder, Niger.
authors.forename: Oumarou
authors.initials: O
authors.lastname: Habou
mesh_terms: D015746:Abdominal Pain / Q000209:etiology; D000208:Acute Disease; D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002446:Celiac Disease / Q000150:complications* / Q000628:therapy; D003520:Cyclophosphamide / Q000627:therapeutic use; D055050:Diet, Gluten-Free; D004317:Doxorubicin / Q000627:therapeutic use; D058527:Enteropathy-Associated T-Cell Lymphoma / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology; D005047:Etoposide / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007415:Intestinal Obstruction / Q000209:etiology*; D011239:Prednisolone / Q000627:therapeutic use; D014750:Vincristine / Q000627:therapeutic use
chemical_list: D014750:Vincristine; D005047:Etoposide; D004317:Doxorubicin; D003520:Cyclophosphamide; D011239:Prednisolone
keywords: Celiac disease; EATL; T-cell lymphoma; bowel obstruction; surgery