title: [Indication and Efficacy of Amniotic Membrane Transplantation Performed under Advanced Medical Healthcare].
abstract: OBJECTIVE
  To survey indications and outcomes of amniotic membrane transplantation (AMT) performed under Advanced Medical Healthcare (AMH) in Japan.
  
  
  METHODS
  Questionnaires were sent to 21 facilities performing AMT under AMH from 2010-2012. Diagnosis, effectiveness, and final outcomes were surveyed. Moreover, we retrospectively examined the diagnosis, treatment effectiveness, and final outcomes in all AMTs performed under AMH at Kyoto Prefectural University of Medicine (KPUM) from April 2009 through June 2013.
  
  
  RESULTS
  Clinical data of 311 eyes that underwent AMT under AMH was obtained. Of those, diagnoses included pterygium (n = 148), corneal ulcer/epithelial defect (n = 60), corneal perforation (n = 28), intractable glaucoma (n = 24), and others (n = 51). The surgical outcome was completely or partially successful in 287 eyes (92.3%). The final outcome was effective in 281 eyes (90.4%). A total of 45 eyes of 37 patients underwent AMT under AMH at KPUM. Of those, diagnoses included pterygium (n = 15), recurrence of pterygium (n = 27), and symblepharon (n = 3). The surgical outcome was completely successful in 98% and partially successful in 2%. The final outcome was effective in all cases.
  
  
  CONCLUSIONS
  AMT performed under AMH in Japan was most common in eyes with pterygium, and was highly effective in these cases, as well as corneal ulcer/epithelial defect, corneal perforation, and intractable glaucoma.
authors.forename: Keisuke
authors.initials: K
authors.lastname: Morikawa
authors.forename: Chie
authors.initials: C
authors.lastname: Sotozono
authors.forename: Tsutomu
authors.initials: T
authors.lastname: Inatomi
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakamura
authors.forename: Norihiko
authors.initials: N
authors.lastname: Yokoi
authors.forename: Yasutoshi
authors.initials: Y
authors.lastname: Matsuo
authors.forename: Shigeru
authors.initials: S
authors.lastname: Kinoshita
mesh_terms: D000650:Amnion / Q000637:transplantation*; D003320:Corneal Ulcer / Q000601:surgery; D005901:Glaucoma / Q000601:surgery; D006801:Humans; D011625:Pterygium / Q000601:surgery; D012189:Retrospective Studies; D011795:Surveys and Questionnaires; D014184:Transplantation, Homologous; D016896:Treatment Outcome