title: A DNAzyme-mediated logic gate for programming molecular capture and release on DNA origami.
abstract: Here we design a DNA origami-based site-specific molecular capture and release platform operated by a DNAzyme-mediated logic gate process. We show the programmability and versatility of this platform with small molecules, proteins, and nanoparticles, which may also be controlled by external light signals.
authors.affiliation: School of Mechanical Engineering, Purdue University, West Lafayette, Indiana 47907, USA. jchoi@purdue.edu.
authors.forename: Feiran
authors.initials: F
authors.lastname: Li
authors.affiliation: School of Mechanical Engineering, Purdue University, West Lafayette, Indiana 47907, USA. jchoi@purdue.edu.
authors.forename: Haorong
authors.initials: H
authors.lastname: Chen
authors.affiliation: School of Mechanical Engineering, Purdue University, West Lafayette, Indiana 47907, USA. jchoi@purdue.edu.
authors.forename: Jing
authors.initials: J
authors.lastname: Pan
authors.affiliation: School of Mechanical Engineering, Purdue University, West Lafayette, Indiana 47907, USA. jchoi@purdue.edu.
authors.forename: Tae-Gon
authors.initials: TG
authors.lastname: Cha
authors.affiliation: Centre for Bio/Molecular Science and Engineering, Code 6900 U.S. Naval Research Laboratory, Washington DC 20375, USA. igor.medintz@nrl.navy.mil.
authors.forename: Igor L
authors.initials: IL
authors.lastname: Medintz
authors.affiliation: School of Mechanical Engineering, Purdue University, West Lafayette, Indiana 47907, USA. jchoi@purdue.edu.
authors.forename: Jong Hyun
authors.initials: JH
authors.lastname: Choi
mesh_terms: D039301:Computers, Molecular; D004247:DNA / Q000737:chemistry*; D021881:DNA, Catalytic / Q000378:metabolism*; D008128:Logic; D009690:Nucleic Acid Conformation
chemical_list: D021881:DNA, Catalytic; D004247:DNA