title: Site of Mammalian Sperm Acrosome Reaction.
abstract: Until recently, no special attention has been paid to the question of the site of mammalian sperm acrosome reaction (AR) in the female reproductive tract. Because AR is an essential process that enables the spermatozoon to fertilize, it is generally believed that it occurs at a specific step during sperm-egg interaction. It is generally thought that "the site of action coincides with the site of commitment." Thus, understanding the roles of AR and acrosomal substances is needed to gain insight into the site of the sperm commitment to undergo AR.
authors.affiliation: Oki Marine Biological Station, Education and Research Center for Biological Resources, Shimane University, 194 Kamo, Okinoshima-cho, Oki, Shimane, 685-0024, Japan. hiro@life.shimane-u.ac.jp.
authors.forename: Noritaka
authors.initials: N
authors.lastname: Hirohashi
mesh_terms: D000177:Acrosome / Q000502:physiology* / Q000648:ultrastructure; D020101:Acrosome Reaction / Q000502:physiology*; D000818:Animals; D004527:Egg Proteins / Q000235:genetics / Q000378:metabolism; D005187:Fallopian Tubes / Q000033:anatomy & histology / Q000502:physiology*; D005260:Female; D005786:Gene Expression Regulation; D007136:Immunoglobulins / Q000235:genetics / Q000378:metabolism; D008297:Male; D008562:Membrane Glycoproteins / Q000235:genetics / Q000378:metabolism; D008565:Membrane Proteins / Q000235:genetics / Q000378:metabolism; D051379:Mice; D011956:Receptors, Cell Surface / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction; D013075:Sperm Capacitation / Q000502:physiology*; D015044:Zona Pellucida / Q000502:physiology* / Q000648:ultrastructure; D000072216:Zona Pellucida Glycoproteins
chemical_list: D004527:Egg Proteins; D007136:Immunoglobulins; C498177:Izumo1 protein, mouse; D008562:Membrane Glycoproteins; D008565:Membrane Proteins; D011956:Receptors, Cell Surface; D000072216:Zona Pellucida Glycoproteins; C094480:sp56 protein, mouse