title: Correlation of A2bAR and KLF4/KLF15 with Obesity-Dyslipidemia Induced Inflammation in Uygur Population.
abstract: In this paper, the researchers collected visceral adipose tissue from the Uygur population, which were divided into two groups: the normal control group (NC, n = 50, 18.0 kg/m(2) ≤ BMI ≤ 23.9 kg/m(2)) and the obese group (OB, n = 45, BMI ≥ 28 kg/m(2)), and then use real-time PCR to detect the mRNA expression level of key genes involved in inflammation signaling pathway. The findings suggest that, in obese status, the lower expression level of A2bAR, KLF4, and KLF15 of visceral adipose tissue may correlate with obese-dyslipidemia induced inflammation in Uygur population.
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Cuizhe
authors.initials: C
authors.lastname: Wang
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Xiaodan
authors.initials: X
authors.lastname: Ha
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China; The First Affiliated Hospital Clinical Laboratory, Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Li
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Xu
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Yajuan
authors.initials: Y
authors.lastname: Gu
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Tingting
authors.initials: T
authors.lastname: Wang
authors.affiliation: Endocrinology Department, Xinjiang Uygur Autonomous Region People's Hospital, Urumqi, Xinjiang 830001, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Jianxin
authors.initials: J
authors.lastname: Xie
authors.affiliation: Shihezi University School of Medicine, Shihezi, Xinjiang 832000, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000273:Adipose Tissue / Q000378:metabolism; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D050171:Dyslipidemias / Q000235:genetics / Q000378:metabolism*; D005260:Female; D006801:Humans; D007249:Inflammation / Q000235:genetics / Q000378:metabolism*; D000090062:Kruppel-Like Factor 4; D051741:Kruppel-Like Transcription Factors / Q000235:genetics / Q000378:metabolism*; D008297:Male; D008875:Middle Aged; D009687:Nuclear Proteins / Q000235:genetics / Q000378:metabolism*; D009765:Obesity / Q000235:genetics / Q000378:metabolism*; D043705:Receptor, Adenosine A2A / Q000235:genetics / Q000378:metabolism*; D055815:Young Adult
chemical_list: C414172:KLF15 protein, human; C000715467:KLF4 protein, human; D000090062:Kruppel-Like Factor 4; D051741:Kruppel-Like Transcription Factors; D009687:Nuclear Proteins; D043705:Receptor, Adenosine A2A