title: Which Patients With Ossifying Fibroma of the Jaws Would Be Suitable for Radical Ablative Surgery?
abstract: OBJECTIVE
  The aim of authors' study was to present their 10-year experience in the treatment of giant ossifying fibroma (GOF), and to prove if GOF can be totally excised preventing recurrence. The authors' secondary goal was to study the aesthetic and functional outcomes after radical resection of GOF followed by immediate reconstruction.
  
  
  METHODS
  Eighteen patients who underwent radical ablative surgery of GOF of the jaw followed by immediate reconstruction with vascularized fibula flap or ilium flap between May 2003 and May 2013 were taken. Recurrence rate was statistically observed and 2-year postoperative aesthetic and functional outcomes were evaluated.
  
  
  RESULTS
  The average length of follow-up was 4.5 years. There was no residual tumor or tumor recurrence observed in any patient during the mean follow-up of 4.5 years, and good cosmesis and functional outcome was noted after ablative surgery of GOF followed by computer-assisted reconstruction.
  
  
  CONCLUSIONS
  For giant OF, if it is mainly located in the jaws without invasion of the skull base and/or pterygoid process, radical surgical treatment should be performed for prevention of tumor recurrence. And good aesthetic and functional results can be achieved by immediate computer-assisted reconstruction and dental rehabilitation.
authors.affiliation: *Department of Oral Maxillofacial-Head Neck Oncology, Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Key Laboratory of Stomatology, Shanghai, China †Department of Consulting and Diagnostics, Central Research Institute of Dentistry and Maxillofacial Surgery ‡Department of Oral and Maxillofacial Surgery, Russian Medical Academy of Postgraduate Education Studies, Moscow, Russia.
authors.forename: Mingming
authors.initials: M
authors.lastname: Lv
authors.forename: Yi
authors.initials: Y
authors.lastname: Shen
authors.forename: Jun
authors.initials: J
authors.lastname: Li
authors.forename: Shalva R
authors.initials: SR
authors.lastname: Gvetadze
authors.forename: Jian
authors.initials: J
authors.lastname: Sun
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D018214:Fibroma, Ossifying / Q000000981:diagnostic imaging / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D021621:Imaging, Three-Dimensional; D008297:Male; D008339:Mandibular Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D063168:Mandibular Osteotomy; D008441:Maxillary Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D063166:Maxillary Osteotomy / Q000379:methods*; D008875:Middle Aged; D025321:Surgery, Computer-Assisted; D014057:Tomography, X-Ray Computed; D014584:User-Computer Interface; D055815:Young Adult