title: Reagents for diverse iodosilane-mediated transformations.
abstract: It was observed that a PhSiH2I-mediated protocol using PhSiH3 and cat. I2 caused the deiodination of 2-(iodomethyl)-2-phenyltetrahydrofuran. Stemming from the investigation of the mechanism, we found that the PhSiH3-I2 system selectively promotes diverse cascade transformations from cyclic ethers to acyclic alkyl iodides, and the PhSiH3-N-iodosuccinimide (NIS) system also promotes cascade transformations from cyclic ethers to acyclic alcohols.
authors.affiliation: Department of Basic Medicinal Sciences, Graduate School of Pharmaceutical Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya 464-8601, Japan. m-shibu@ps.nagoya-u.ac.jp.
authors.forename: Masatoshi
authors.initials: M
authors.lastname: Shibuya
authors.forename: Masanori
authors.initials: M
authors.lastname: Abe
authors.forename: Shoji
authors.initials: S
authors.lastname: Fujita
authors.forename: Yoshihiko
authors.initials: Y
authors.lastname: Yamamoto