title: Scarlet Fever Upsurge in England and Molecular-Genetic Analysis in North-West London, 2014.
abstract: Scarlet fever notifications surged across the United Kingdom in spring 2014. Molecular epidemiologic investigation of Streptococcus pyogenes infections in North-West London highlighted increased emm4 and emm3 infections coincident with the upsurge. Unlike outbreaks in other countries, antimicrobial resistance was uncommon, highlighting an urgent need to better understand the drivers of scarlet fever activity.
authors.forename: Claire E
authors.initials: CE
authors.lastname: Turner
authors.forename: Marta
authors.initials: M
authors.lastname: Pyzio
authors.forename: Bonita
authors.initials: B
authors.lastname: Song
authors.forename: Theresa
authors.initials: T
authors.lastname: Lamagni
authors.forename: Margie
authors.initials: M
authors.lastname: Meltzer
authors.forename: J Yimmy
authors.initials: JY
authors.lastname: Chow
authors.forename: Androulla
authors.initials: A
authors.lastname: Efstratiou
authors.forename: Sally
authors.initials: S
authors.lastname: Curtis
authors.forename: Shiranee
authors.initials: S
authors.lastname: Sriskandan
mesh_terms: D000942:Antigens, Bacterial / Q000235:genetics / Q000276:immunology; D005838:Genotype; D049674:History, 21st Century; D006801:Humans; D008131:London / Q000453:epidemiology; D009154:Mutation; D012541:Scarlet Fever / Q000453:epidemiology* / Q000266:history / Q000276:immunology / Q000382:microbiology*; D013297:Streptococcus pyogenes / Q000145:classification* / Q000187:drug effects / Q000235:genetics* / Q000276:immunology; D018089:Superantigens / Q000235:genetics / Q000276:immunology
chemical_list: D000942:Antigens, Bacterial; D018089:Superantigens
keywords: England; London; Streptococcus pyogenes; antimicrobial resistance; bacteria; genotype; notifications; respiratory infections; scarlet fever; streptococci; superantigens