title: Is Chronic Obstructive Pulmonary Disease Caused by Wood Smoke a Different Phenotype or a Different Entity?
abstract: Around 40% of the world's population continue using solid fuel, including wood, for cooking or heating their homes. Chronic exposure to wood smoke is a risk factor for developing chronic obstructive pulmonary disease (COPD). In some regions of the world, this can be a more important cause of COPD than exposure to tobacco smoke from cigarettes. Significant differences between COPD associated with wood smoke (W-COPD) and that caused by smoking (S-COPD) have led some authors to suggest that W-COPD should be considered a new COPD phenotype. We present a review of the differences between W-COPD and S-COPD. On the premise that wood smoke and tobacco smoke are not the same and the physiopathological mechanisms they induce may differ, we have analyzed whether W-COPD can be considered as another COPD phenotype or a distinct nosological entity.
authors.affiliation: Fundación Neumológica Colombiana, Universidad de La Sabana, Bogotá, Colombia. Electronic address: ctorres@neumologica.org.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Torres-Duque
authors.affiliation: Fundación Neumológica Colombiana, Bogotá, Colombia.
authors.forename: María Carmen
authors.initials: MC
authors.lastname: García-Rodriguez
authors.affiliation: Fundación Neumológica Colombiana, Universidad de La Sabana, Bogotá, Colombia.
authors.forename: Mauricio
authors.initials: M
authors.lastname: González-García
mesh_terms: D000367:Age Factors; D018533:Biomass; D003906:Developing Countries; D003948:Diagnostic Techniques, Respiratory System; D005260:Female; D005579:Fossil Fuels / Q000009:adverse effects; D006801:Humans; D006976:Hypertension, Pulmonary / Q000209:etiology; D019570:Inhalation Exposure; D008297:Male; D015201:Meta-Analysis as Topic; D010641:Phenotype; D029424:Pulmonary Disease, Chronic Obstructive / Q000145:classification* / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D011656:Pulmonary Emphysema / Q000209:etiology; D011788:Quality of Life; D012737:Sex Factors; D012906:Smoke / Q000009:adverse effects*; D063189:Symptom Assessment; D014028:Tobacco Smoke Pollution / Q000009:adverse effects; D016896:Treatment Outcome; D014934:Wood; D014026:Nicotiana
chemical_list: D005579:Fossil Fuels; D012906:Smoke; D014028:Tobacco Smoke Pollution
keywords: Biomasa; Biomass; Chronic obstructive pulmonary disease; Enfermedad pulmonar obstructiva crónica; Fenotipo; Humo de leña; Phenotype; Wood smoke