title: Pregnancy in the liver transplant recipient.
abstract: During gestation, the woman's body undergoes various changes, and the line between physiology and pathology is very thin even in healthy women. Today, many of the liver transplant recipients are young women, who at one point in their lives may consider the possibility of pregnancy. Clinicians have to counsel them about the time of conception, the risk of miscarriage, the deterioration of the mother's health status, and the risk of birth defects. This review, based on our 20 years of clinical experience and up-to-date literature, provides comprehensive guidelines on pregnancy management in liver transplant recipients. Pregnancy in liver transplant recipients is possible but never physiological. Proper management and pharmacotherapy lowers the incidence of complications and birth defects. Critical factors for perinatal success include stable graft function before pregnancy, proper preparation for pregnancy, and cautious observation during its course. Liver Transplantation 22 1408-1417 2016 AASLD.
authors.affiliation: 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.
authors.forename: Zoulikha
authors.initials: Z
authors.lastname: Jabiry-Zieniewicz
authors.affiliation: 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland. fil.dabrowski@gmail.com.
authors.forename: Filip Andrzej
authors.initials: FA
authors.lastname: Dabrowski
authors.affiliation: 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.
authors.forename: Bronislawa
authors.initials: B
authors.lastname: Pietrzak
authors.affiliation: Department of Nephrological Nursing, Medical University of Warsaw, Warsaw, Poland.
authors.forename: Janusz
authors.initials: J
authors.lastname: Wyzgal
authors.affiliation: 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.
authors.forename: Dorota
authors.initials: D
authors.lastname: Bomba-Opoń
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Zieniewicz
authors.affiliation: 1st Department of Obstetrics and Gynecology, Medical University of Warsaw, Warsaw, Poland.
authors.forename: Miroslaw
authors.initials: M
authors.lastname: Wielgos
mesh_terms: D000022:Abortion, Spontaneous / Q000517:prevention & control; D000013:Congenital Abnormalities; D005260:Female; D005306:Fertilization; D006304:Health Status; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D017093:Liver Failure / Q000601:surgery*; D016031:Liver Transplantation; D011247:Pregnancy; D011248:Pregnancy Complications / Q000453:epidemiology*; D011256:Pregnancy Outcome; D012042:Registries; D012307:Risk Factors
chemical_list: D007166:Immunosuppressive Agents