title: Predictive Factors of Spontaneous Reporting of Adverse Drug Reactions among Community Pharmacists.
abstract: To evaluate the association between spontaneous reporting (SR) and the knowledge, attitude, and needs of community pharmacists (CPs), using a questionnaire following a conceptual model known as the mixed model of knowledge-attitude-practices and the satisfaction of needs.
  
  
  
  Self-administered questionnaires were used with a nationwide convenience sample of CPs between September 1, 2014 and November 25, 2014 in Korea. The association between SR and the predictive factors was evaluated using multivariate logistic regression analysis.
  
  
  
  In total, 1,001 questionnaires were analyzed. The mean age of the respondents and the number of years spent in community pharmacy practice were 45.6 years and 15.3 years, respectively. CPs with experience of SR was 29.4%. Being older than 60 (ORadj, 0.16; 95% CI, 0.06-0.42), having prior experience with adverse drug reactions (ADR) (ORadj, 6.46; 95% CI, 2.46-16.98), having higher specific knowledge of SR (ORadj, 3.58; 95% CI, 1.96-6.56), and having less concern about the obstacles to SR (ORadj, 0.36; 95% CI, 0.23-0.57) were significant contributing factors to SR. The main obstacles to SR included perception of ADRs as 'not serious ADR' (77.9%), 'already well known ADR' (81.5%), and 'uncertain about causality' (73.3%). CPs without reporting experience had greater concerns related to the reporting method and the liability of the pharmacy than those with reporting experience (p<0.05).
  
  
  
  Findings from our study showed around one in three CPs had ADR reporting experience in Korea, while 87.1% had prior experience with ADR cases. The knowledge of SR, prior experience of ADR, and less concern about the obstacles to SR were contributing factors for reporting levels.
authors.affiliation: College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
authors.forename: Yun Mi
authors.initials: YM
authors.lastname: Yu
authors.affiliation: College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
authors.forename: Euni
authors.initials: E
authors.lastname: Lee
authors.affiliation: College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
authors.forename: Bon Sun
authors.initials: BS
authors.lastname: Koo
authors.affiliation: College of Pharmacy, Chung-Ang University, Seoul, South Korea.
authors.forename: Kyeong Hye
authors.initials: KH
authors.lastname: Jeong
authors.affiliation: College of Pharmacy, Suncheon University, Suncheon, Joellanam-do, South Korea.
authors.forename: Kyung Hee
authors.initials: KH
authors.lastname: Choi
authors.affiliation: College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
authors.forename: Lee Kyung
authors.initials: LK
authors.lastname: Kang
authors.affiliation: Regional Pharmacovigilance Center, Korean Pharmaceutical Association, Seoul, South Korea.
authors.forename: Mo Se
authors.initials: MS
authors.lastname: Lee
authors.affiliation: Regional Pharmacovigilance Center, Korean Pharmaceutical Association, Seoul, South Korea.
authors.forename: Kwang Hoon
authors.initials: KH
authors.lastname: Choi
authors.affiliation: College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
authors.forename: Jung Mi
authors.initials: JM
authors.lastname: Oh
authors.affiliation: College of Pharmacy & Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
authors.forename: Wan Gyoon
authors.initials: WG
authors.lastname: Shin
mesh_terms: D000328:Adult; D016907:Adverse Drug Reaction Reporting Systems; D001291:Attitude of Health Personnel; D003430:Cross-Sectional Studies; D064420:Drug-Related Side Effects and Adverse Reactions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010594:Pharmacies; D010595:Pharmacists; D060735:Pharmacovigilance; D015203:Reproducibility of Results; D056910:Republic of Korea; D011795:Surveys and Questionnaires