title: Treatment of Hypersplenism by Partial Splenic Embolization Through Gastric Collaterals.
abstract: We report a case of Chronic lymphocytic leukemia (CLL) with associated hypersplenism, that was referred to us for partial splenic embolization (PSE) as the patient was not a surgical candidate for splenectomy. Initially, we were not successful in catheterizing the splenic artery from the celiac trunk due to significant atherosclerotic disease. Therefore, we successfully managed to access the distal splenic artery through patent gastro-epiploic collateral circulation along the greater curvature of the stomach. Partial splenic embolization was successfully performed and resulted in improvement of the patient's peripheral blood cell count as well as 60-70% reduction in the size of the spleen on follow up. Our case highlights an alternative pathway for splenic artery embolization when catheterization of the splenic artery is not feasible. To our knowledge, the use of gastro-epiploic collaterals to embolize the spleen has not been previously reported in literature.
authors.affiliation: Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.
authors.forename: Souheil
authors.initials: S
authors.lastname: Saddekni
authors.affiliation: Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA; Department of Radiology, Zagazig University, Zagazig, Egypt.
authors.forename: Amr Soliman
authors.initials: AS
authors.lastname: Moustafa
authors.affiliation: Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.
authors.forename: Hany A
authors.initials: HA
authors.lastname: Tahoon
authors.affiliation: Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA.
authors.forename: Mostafa
authors.initials: M
authors.lastname: Setita
authors.affiliation: Department of Radiology, University of Alabama at Birmingham (UAB), Birmingham, Alabama, USA; Department of Radiology, University of Cairo, Cairo, Egypt.
authors.forename: Ahmed Kamel
authors.initials: AK
authors.lastname: Abdel-Aal
mesh_terms: D000368:Aged; D003097:Collateral Circulation; D004621:Embolization, Therapeutic / Q000379:methods*; D006801:Humans; D006971:Hypersplenism / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy*; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications; D008297:Male; D013270:Stomach / Q000098:blood supply*; D014057:Tomography, X-Ray Computed
keywords: Chronic lymphocytic leukemia; Gastro-epiploic collaterals; Hypersplenism; Splenic artery calcification; Splenic embolization