title: Self-reported gadolinium toxicity: A survey of patients with chronic symptoms.
abstract: This study aims to describe the self-reporting symptoms experienced by individuals with self-reported normal renal function after gadolinium based contrast agent (GBCA) administration.
  
  
  
  This HIPAA-compliant, IRB-approved study consisted of an anonymous online survey of patients who believe that they suffer from gadolinium toxicity. 50 respondents completed the nine-question survey.
  
  
  
  Fifty (100%) of the subjects ascribed their complaints to gadolinium exposure. Thirty-three (66%) described the onset immediately following GBCA administration and 16 (32%) within 6weeks. The most common symptoms included bone/joint pain and head/neck symptoms including headache, vision change, and hearing change (77.6% each). Other symptoms occurred with lesser incidence.
  
  
  
  This survey represents an initial description of patients with normal renal function who self-described toxicity related to GBCA administration. Bone and joint complaints and skin changes are two of the most common complaints.
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
authors.forename: Lauren M B
authors.initials: LM
authors.lastname: Burke
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
authors.forename: Miguel
authors.initials: M
authors.lastname: Ramalho
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
authors.forename: Mamdoh
authors.initials: M
authors.lastname: AlObaidy
authors.affiliation: Department of Medicine, Division of Nephrology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Chang
authors.affiliation: Department of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Jay
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA. Electronic address: richsem@med.unc.edu.
authors.forename: Richard C
authors.initials: RC
authors.lastname: Semelka
mesh_terms: D002908:Chronic Disease; D003287:Contrast Media / Q000506:poisoning*; D005260:Female; D005682:Gadolinium / Q000506:poisoning*; D006801:Humans; D008297:Male; D057566:Self Report
chemical_list: D003287:Contrast Media; D005682:Gadolinium
keywords: Chronic; Gadolinium; Survey; Symptoms; Toxicity