title: An Unusual Presentation of B-Cell Lymphoma as a Large Isolated Epiglottic Mass: Case Report and Literature Review.
abstract: Extranodal presentation of B-cell lymphoma is uncommon. Isolated primary epiglottic B-cell lymphoma is even rarer. To our knowledge, there has been only one description of isolated B-cell lymphoma presenting as a large epiglottic mass. We report an unusual type of B-cell lymphoma of the epiglottis, as it could not be subtyped based on routine staining and hybridization. The lymphoma presented as a large isolated globular mass pedicled to the epiglottis, occupying most of the oropharynx, but did not have any ball-valving effect or increased respiratory efforts. Initial radiographic findings were nonspecific. The diagnosis of B-cell lymphoma was determined by transoral incisional biopsy under local anesthesia. The condition was treated successfully with chemoradiation. The current standard of treatment for high grade B-cell lymphoma is concurrent chemoradiotherapy, with excellent prognosis. Although rare, B-cell lymphoma should be considered when investigating pedunculated hypopharyngeal masses.
authors.affiliation: Department of Otolaryngology, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA.
authors.forename: Changxing
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Otolaryngology, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA.
authors.forename: Sean
authors.identifier: 0000-0002-8587-7009
authors.initials: S
authors.lastname: Delaney
authors.affiliation: Department of Otolaryngology, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA.
authors.forename: Tamara N
authors.initials: TN
authors.lastname: Brown