title: [Smart eye data : Development of a foundation for medical research using Smart Data applications].
abstract: BACKGROUND
  Smart Data means intelligent data accumulation and the evaluation of large data sets. This is particularly important in ophthalmology as more and more data are being created. Increasing knowledge and personalized therapies are expected by combining clinical data from electronic health records (EHR) with measurement data.
  
  
  OBJECTIVE
  In this study we investigated the possibilities to consolidate data from measurement devices and clinical data in a data warehouse (DW).
  
  
  METHODS
  An EHR was adjusted to the needs of ophthalmology and the contents of referral letters were extracted. The data were imported into a DW overnight. Measuring devices were connected to the EHR by an HL7 standard interface and the use of a picture archiving and communications system (PACS). Data were exported from the review software using a self-developed software. For data analysis the software was modified to the specific requirements of ophthalmology.
  
  
  RESULTS
  In the EHR 12 graphical user interfaces were created and the data from 32,234 referral letters were extracted. A total of 23 diagnostic devices could be linked to the PACS and 85,114 optical coherence tomography (OCT) scans, 19,098 measurements from IOLMaster as well as 5,425 pentacam examinations were imported into the DW including over 300,000 patients. Data discovery software was modified providing filtering methods.
  
  
  CONCLUSIONS
  By building a DW a foundation for clinical and epidemiological studies could be implemented. In the future, decision support systems and strategies for personalized therapies can be based on such a database.
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland. karsten.kortuem@med.uni-muenchen.de.
authors.forename: K
authors.initials: K
authors.lastname: Kortüm
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Müller
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Hirneiß
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Babenko
authors.affiliation: Institut für Biometrie und Epidemiologie in der Medizin, Universität München, München, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Nasseh
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Kern
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Kampik
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Priglinger
authors.affiliation: Augenklinik, Universität München, Mathildenstr. 8, 80336, München, Deutschland.
authors.forename: T C
authors.initials: TC
authors.lastname: Kreutzer
mesh_terms: D066264:Datasets as Topic / Q000706:statistics & numerical data*; D057286:Electronic Health Records / Q000706:statistics & numerical data*; D005128:Eye Diseases / Q000175:diagnosis* / Q000453:epidemiology*; D005858:Germany / Q000453:epidemiology; D006801:Humans; D016247:Information Storage and Retrieval / Q000379:methods*; D008498:Medical Record Linkage / Q000379:methods; D015995:Prevalence; D011873:Radiology Information Systems / Q000706:statistics & numerical data*; D012042:Registries / Q000706:statistics & numerical data*; D012307:Risk Factors
keywords: Data; Digital; Image library; Measurement data; Ophthalmology