title: Ventilatory Responses to Hypercarbia in Infants of Mothers Who Smoke and Misuse Substances.
abstract: The ventilatory response of infants of mothers who smoke and misuse substances and controls to carbon dioxide was assessed at 6-12 weeks and the perinatal period. Infants of mothers who smoke and misuse substances had a dampened response at the peak age of sudden infant death syndrome, greater than in the perinatal period.
authors.affiliation: Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.
authors.forename: Kamal
authors.initials: K
authors.lastname: Ali
authors.affiliation: Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.
authors.forename: Thomas
authors.initials: T
authors.lastname: Rossor
authors.affiliation: Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.
authors.forename: Ravindra
authors.initials: R
authors.lastname: Bhat
authors.affiliation: Addiction Sciences Unit, King's College London, London, United Kingdom.
authors.forename: Kim
authors.initials: K
authors.lastname: Wolff
authors.affiliation: Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.
authors.forename: Simon
authors.initials: S
authors.lastname: Hannam
authors.affiliation: Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom.
authors.forename: Gerrard F
authors.initials: GF
authors.lastname: Rafferty
authors.affiliation: Division of Asthma, Allergy and Lung Biology, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, King's College London, London, United Kingdom; NIHR Biomedical Centre at Guy's and St Thomas NHS Foundation Trust and King's College London, London, United Kingdom. Electronic address: anne.greenough@kcl.ac.uk.
authors.forename: Anne
authors.initials: A
authors.lastname: Greenough
mesh_terms: D002245:Carbon Dioxide / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006935:Hypercapnia / Q000503:physiopathology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008425:Maternal Behavior; D011247:Pregnancy; D011248:Pregnancy Complications; D011297:Prenatal Exposure Delayed Effects / Q000209:etiology*; D012119:Respiration; D012129:Respiratory Function Tests; D012307:Risk Factors; D012907:Smoking; D019966:Substance-Related Disorders; D013398:Sudden Infant Death / Q000209:etiology; D014028:Tobacco Smoke Pollution / Q000009:adverse effects
chemical_list: D014028:Tobacco Smoke Pollution; D002245:Carbon Dioxide
keywords: maternal smoking; maternal substance misuse; respiratory control; sudden infant death syndrome