title: The Effect of Pressure-Controlled Ventilation and Volume-Controlled Ventilation in Prone Position on Pulmonary Mechanics and Inflammatory Markers.
abstract: The aim of this present study is to compare the effect of pressure-controlled ventilation and volume-controlled ventilation on pulmonary mechanics and inflammatory markers in prone position. The study included 41 patients undergoing to vertebrae surgery. The patients were randomized into two groups: Group 1 received volume-controlled ventilation, while group 2 received pressure-controlled ventilation. The demographic data, pulmonary mechanics, the inflammatory marker levels just after the induction of anesthetics, at the 6th and 12th hours, and gas analysis from arterial blood samples taken at the beginning and the 30th minute were recorded. The inflammatory marker levels increased in both groups, without any significant difference among groups. Peak inspiratory pressure level was higher in the volume-controlled ventilation group. This study revealed that there is no difference regarding inflammatory marker levels between volume- and pressure-controlled ventilation.
authors.affiliation: Medical Faculty Department of Anesthesia and Reanimation, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Hasan
authors.initials: H
authors.lastname: Şenay
authors.affiliation: Medical Faculty Department of Anesthesia and Reanimation, Afyon Kocatepe University, Afyonkarahisar, Turkey. remziyesivaci@gmail.com.|Tıp Fakültesi, Anesteziyoloji ve Reanimasyon AD, Kocatepe Üniversitesi, İzmir Yolu 8. Km, Afyonkarahisar, Turkey. remziyesivaci@gmail.com.
authors.forename: Remziye
authors.initials: R
authors.lastname: Sıvacı
authors.affiliation: Medical Faculty Department of Anesthesia and Reanimation, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Serdar
authors.initials: S
authors.lastname: Kokulu
authors.affiliation: Medical Faculty Department of Medical Biochemistry, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Buğra
authors.initials: B
authors.lastname: Koca
authors.affiliation: Medical Faculty Department of Anesthesia and Reanimation, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Elif Doğan
authors.initials: ED
authors.lastname: Bakı
authors.affiliation: Medical Faculty Department of Anesthesia and Reanimation, Afyon Kocatepe University, Afyonkarahisar, Turkey.
authors.forename: Yüksel
authors.initials: Y
authors.lastname: Ela
mesh_terms: D015415:Biomarkers / Q000097:blood; D001784:Blood Gas Analysis; D006801:Humans; D007249:Inflammation / Q000175:diagnosis; D008168:Lung / Q000502:physiology; D011312:Pressure; D016684:Prone Position; D012121:Respiration, Artificial / Q000379:methods*; D012129:Respiratory Function Tests; D013990:Tidal Volume; D012122:Ventilators, Mechanical / Q000592:standards*
chemical_list: D015415:Biomarkers
keywords: inflammation; pressure controlled ventilation; prone position; volume controlled ventilation