title: Surgical Challenges of Familial Hypercholesterolemia.
abstract: A 21-year-old patient with familial hypercholesterolemia presented with angina caused by ostial stenosis of the left internal mammary artery and severe calcific aortic stenosis with small aortic root 9 years after coronary revascularization. The ostium of the left internal mammary artery was enlarged using a saphenous vein patch through a left supraclavicular incision, which improved left ventricular function. Successful aortic valve replacement with posterior aortic root enlargement was subsequently performed. The surgical management of this condition is discussed briefly.
authors.affiliation: Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Amolkumar
authors.initials: A
authors.lastname: Bhoje
authors.affiliation: Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Sachin
authors.initials: S
authors.lastname: Talwar
authors.affiliation: Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Rachit
authors.initials: R
authors.lastname: Saxena
authors.affiliation: Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Parag
authors.initials: P
authors.lastname: Gharde
authors.affiliation: Cardiothoracic Centre, All India Institute of Medical Sciences, New Delhi, India. Electronic address: shivchoudhary@hotmail.com.
authors.forename: Shiv Kumar
authors.initials: SK
authors.lastname: Choudhary
mesh_terms: D000787:Angina Pectoris / Q000000981:diagnostic imaging / Q000209:etiology; D001024:Aortic Valve Stenosis / Q000150:complications / Q000601:surgery*; D001157:Arterial Occlusive Diseases / Q000150:complications / Q000601:surgery*; D019917:Blood Vessel Prosthesis Implantation / Q000379:methods*; D002114:Calcinosis / Q000601:surgery; D017023:Coronary Angiography; D015150:Echocardiography, Doppler; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D006938:Hyperlipoproteinemia Type II / Q000150:complications* / Q000188:drug therapy; D000960:Hypolipidemic Agents / Q000627:therapeutic use; D007387:Internal Mammary-Coronary Artery Anastomosis / Q000379:methods*; D008297:Male; D008323:Mammary Arteries / Q000000981:diagnostic imaging / Q000601:surgery*; D012008:Recurrence; D012501:Saphenous Vein / Q000637:transplantation; D018487:Ventricular Dysfunction, Left / Q000209:etiology; D055815:Young Adult
chemical_list: D000960:Hypolipidemic Agents