title: A Rare Case of Pulmonary Epithelioid Hemangioendothelioma Presenting with Skin Metastasis.
abstract: Epithelioid hemangioendothelioma (EHE) is a well-differentiated and rare vascular tumor. Systemic metastases are uncommon. Herein, we present a patient with skin metastasis of pulmonary EHE (PEH) that was treated by wide excision. A 76-year-old male was evaluated due to pulmonary thromboembolism and a solitary pulmonary nodule. A biopsy was performed and pathological examination of the mass confirmed EHE. No metastasis was observed. The patient returned to care approximately two years later due to a painful nodule in the right lower leg. A skin biopsy showed metastatic EHE from the lung. We used a safety margin of 1 cm based on clinical experience, because no prior case had been reported regarding the resection margin appropriate for primary cutaneous EHE and skin metastases of PEH. At four months after surgery, the patient recovered without complications or recurrence. Skin metastasis of PEH is extremely rare, and only two cases have been reported in the literature. In this case, we report a rare case of PEH with histologically diagnosed skin metastasis that was successfully treated by curative resection. It is expected that this case report will provide a helpful contribution to the extant data regarding PEH metastases.
authors.affiliation: Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Hyung-Suk
authors.initials: HS
authors.lastname: Ro
authors.affiliation: Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Shin
authors.affiliation: Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Si-Gyun
authors.initials: SG
authors.lastname: Roh
authors.affiliation: Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Nae-Ho
authors.initials: NH
authors.lastname: Lee
authors.affiliation: Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Kyung-Moo
authors.initials: KM
authors.lastname: Yang
authors.affiliation: Department of Pathology, Chonbuk National University Medical School, Jeonju, Korea.
authors.forename: Woo-Sung
authors.initials: WS
authors.lastname: Moon
keywords: Cutaneous surgery; Hemangioendothelioma, epithelioid; Skin