title: Leveraging antimicrobial stewardship into improving rates of carbapenem-resistant Enterobacteriaceae.
abstract: Carbapenem-resistant Enterobacteriaceae (CRE) are among the most critical threats facing our healthcare system and account for significant patient mortality. There is considerable interest in the development of new treatment strategies. However, less attention has been paid to reducing CRE infection rates. Antibiotic stewardship programs can be uniquely empowered to reduce widespread pathogen resistance and by extension, optimize patient care and lower healthcare costs.
authors.affiliation: a Division of Infectious Diseases , USC Keck School of Medicine , Los Angeles , CA , USA.
authors.forename: Darren
authors.initials: D
authors.lastname: Wong
authors.affiliation: a Division of Infectious Diseases , USC Keck School of Medicine , Los Angeles , CA , USA.|b Los Angeles County-USC (LAC + USC) Medical Center , Los Angeles , CA , USA.
authors.forename: Brad
authors.initials: B
authors.lastname: Spellberg
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000073602:Antimicrobial Stewardship / Q000379:methods*; D000073182:Carbapenem-Resistant Enterobacteriaceae / Q000302:isolation & purification*; D004756:Enterobacteriaceae Infections / Q000188:drug therapy* / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans
chemical_list: D000900:Anti-Bacterial Agents
keywords: CRE; KPC; Klebsiella pneumnoniae carbapenemase; antibiotic stewardship