title: Unilateral Optic Neuritis: A Rare Complication after Measles-Mumps-Rubella Vaccination in a 30-Year-Old Woman.
abstract: Purpose. To report a case of unilateral optic neuritis following Measles-Mumps-Rubella (MMR) vaccination. Methods. A 30-year-old female developed unilateral optic neuritis five days after a Measles-Mumps-Rubella (MMR) booster vaccination. The patient displayed unilateral involvement, with severe visual loss. However, visual acuity improved significantly after four days of intravenous steroid therapy with 500 mg/day of methylprednisolone. Conclusions. Optic neuritis is one of the rare complications associated with the mumps, measles, and rubella vaccine. It may be a toxic reaction to the nonviral component of the vaccine, but the exact etiology is unknown. Postvaccination neuritis is generally bilateral and usually affects children. In adults, unilateral optic neuritis is usually correlated with multiple sclerosis (MS).
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: De Giacinto
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Elvira
authors.initials: E
authors.lastname: Guaglione
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Pia E
authors.initials: PE
authors.lastname: Leon
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Rossella
authors.initials: R
authors.lastname: D'Aloisio
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Odilla
authors.initials: O
authors.lastname: Vattovani
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Ravalico
authors.affiliation: University Eye Clinic of Trieste, Ospedale Maggiore, Piazza dell'Ospitale 1, 34125 Trieste, Italy.
authors.forename: Daniele
authors.initials: D
authors.lastname: Tognetto