title: [Combination surgery for wet age-related macular degeneration and chronic peripheral uveitis].
abstract: OBJECTIVE
  To develop a combination surgery for wet age-related macular degeneration and concurrent chronic peripheral uveitis that would include intravitreal injection of Lucentis and cryocerclage of the peripheral retina.
  
  
  METHODS
  A total of 75 patients were examined and divided into 2 groups: the main group (37 patients) and the controls (38 patients). Patients from the main group underwent the new combination surgery, while the controls received intravitreal Lucentis alone (peripheral uveitis was managed therapeutically).
  
  
  RESULTS
  It has been found that the new combination method provides a significant and stable improvement in visual acuity (by a factor of 10) and a decrease in the area of central scotoma (by a factor of 2.95) in the postoperative period. The period needed for recovery in the central retinal thickness is also 1.6 times shorter.
  
  
  CONCLUSIONS
  The new combination surgery for wet age-related macular degeneration and concurrent chronic peripheral uveitis provides rapid reduction of inflammation in the extreme periphery of the fundus and a 1.5 times faster (as compared to traditional methods) primary restoration of topographic anatomy of the retina in the macular region.
authors.affiliation: Siberian State Medical University, Ministry of Health of the Russian Federation, 2 Moskovskiy trakt, Tomsk, Russian Federation, 634050.
authors.forename: I V
authors.initials: IV
authors.lastname: Zapuskalov
authors.affiliation: Siberian State Medical University, Ministry of Health of the Russian Federation, 2 Moskovskiy trakt, Tomsk, Russian Federation, 634050.
authors.forename: O I
authors.initials: OI
authors.lastname: Krivosheina
authors.affiliation: Siberian State Medical University, Ministry of Health of the Russian Federation, 2 Moskovskiy trakt, Tomsk, Russian Federation, 634050.
authors.forename: Yu I
authors.initials: YI
authors.lastname: Khoroshikh
mesh_terms: D000368:Aged; D020533:Angiogenesis Inhibitors / Q000008:administration & dosage; D002908:Chronic Disease; D003131:Combined Modality Therapy; D003941:Diagnostic Techniques, Ophthalmological; D005260:Female; D006801:Humans; D058449:Intravitreal Injections; D008297:Male; D008875:Middle Aged; D013508:Ophthalmologic Surgical Procedures / Q000379:methods*; D000069579:Ranibizumab / Q000008:administration & dosage*; D012607:Scotoma / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D016896:Treatment Outcome; D014605:Uveitis / Q000150:complications / Q000175:diagnosis / Q000628:therapy; D014792:Visual Acuity; D057135:Wet Macular Degeneration / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery
chemical_list: D020533:Angiogenesis Inhibitors; D000069579:Ranibizumab