title: Abdominal scar characteristics as a predictor of cervical stenosis after abdominal radical trachelectomy.
abstract: To investigate whether abdominal scar characteristics could predict the occurrence of cervical stenosis after abdominal radical trachelectomy (ART), we conducted a retrospective study and investigated the relationship between abdominal scar characteristics and the occurrence of cervical stenosis in patients one year after undergoing ART. The abdominal scars were evaluated using the Vancouver Scar Scale (VSS). Seventy-two participants were enrolled in the study, including 15 (20.8%) women with cervical stenosis, and 57 (79.2%) without stenosis. Results showed that the mean abdominal scar score assessed by VSS was higher in patients with cervical stenosis (7, range: 1-10) compared to those without stenosis (4, range: 0-9) (P = 0.001). Incidence rates of cervical stenosis increased with the VSS score. For women with VSS scores of 0 to 4, 5, 6, 7, 8, 9 and 10, respectively, the occurrences of cervical stenosis were 6.1%, 16.7%, 16.7%, 27.3%, 37.5%, 50% and 100%. The cutoff point of VSS score was 7 according to the receiver operating characteristic (ROC) curve. Fourteen of the 15 stenosis happened either in patients without anti-stenosis tools (Foley catheters or tailed intrauterine devices) placed during the surgery or after the devices were removed. Our results demonstrated that VSS is an effective approach to assess the presence of cervical stenosis after ART. Women who have an abdominal scar with a VSS score > 7 have a high risk of developing isthmic stenosis without anti-stenosis tools in place.
authors.affiliation: Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, PR China.|Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, PR China.
authors.forename: Xiaoqi
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, PR China.
authors.forename: Jin
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, PR China.
authors.forename: Xingzhu
authors.initials: X
authors.lastname: Ju
authors.affiliation: Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, PR China.|Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, PR China.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Gynecologic Oncology, Fudan University Shanghai Cancer Center, Shanghai, PR China.
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Wu
mesh_terms: D000328:Adult; D019540:Area Under Curve; D002404:Catheterization / Q000009:adverse effects; D002921:Cicatrix / Q000503:physiopathology*; D003251:Constriction, Pathologic / Q000175:diagnosis* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D012372:ROC Curve; D012189:Retrospective Studies; D012720:Severity of Illness Index; D000267:Tissue Adhesions; D000069339:Trachelectomy / Q000009:adverse effects*; D002583:Uterine Cervical Neoplasms / Q000601:surgery
keywords: Vancouver Scar Scale (VSS); abdominal radical trachelectomy (ART); abdominal scar; cervical cancer; cervical stenosis