title: Trichoblastic carcinosarcoma: an authentic cutaneous carcinosarcoma.
abstract: We describe a trichoblastic carcinosarcoma on the forehead of a 65-year-old man. This is the fifth case of trichoblastic carcinosarcoma in the literature and the first to be reported from the USA. It was successfully treated with direct excision. Trichoblastic carcinosarcoma should be distinguished from epidermal carcinosarcoma. We believe trichoblastic carcinosarcoma is an authentic carcinosarcoma derived from multiple progenitor cells whereas epidermal carcinosarcomas are derived from a single progenitor cell that undergoes epithelial to mesenchymal transition, and are better considered as sarcomatoid carcinomas.
authors.affiliation: University of Kansas School of Medicine, Kansas City, Kansas, USA.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Colston
authors.affiliation: Monarch Plastic Surgery, Kansas City, Missouri, USA.
authors.forename: Keith
authors.initials: K
authors.lastname: Hodge
authors.affiliation: Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine, Kansas City, Kansas, USA.
authors.forename: Garth Robert
authors.initials: GR
authors.lastname: Fraga
mesh_terms: D000368:Aged; D002296:Carcinosarcoma / Q000473:pathology / Q000601:surgery*; D005546:Forehead / Q000473:pathology* / Q000601:surgery; D006801:Humans; D008297:Male; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D016896:Treatment Outcome