title: Surgical Management of Pulmonary Mucosa-Associated Lymphoid Tissue Lymphoma Associated With Light-Chain Deposition Disease.
abstract: A 52-year-old woman presented with a right middle lobe (RML) lung nodule suspicious for malignancy. Thoracoscopic middle lobectomy was performed. The pathology report revealed a pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma in association with light-chain deposition disease (LCDD). Pulmonary MALT lymphoma and LCDD are unusual disorders presenting in the lung, and the association between these 2 conditions is even more uncommon. The optimal management for these patients is controversial, although surgical resection of localized well-circumscribed lesions may represent an effective therapeutic approach.
authors.affiliation: Department of Surgery, Division of Thoracic Surgery, Boston University School of Medicine, Boston, Massachusetts.
authors.forename: Juan A
authors.initials: JA
authors.lastname: Muñoz-Largacha
authors.affiliation: Department of Pathology, Boston University School of Medicine, Boston, Massachusetts.
authors.forename: Carl J
authors.initials: CJ
authors.lastname: O'Hara
authors.affiliation: Department of Hematology and Medical Oncology, Boston University School of Medicine, Boston, Massachusetts.
authors.forename: J Mark
authors.initials: JM
authors.lastname: Sloan
authors.affiliation: Department of Surgery, Division of Thoracic Surgery, Boston University School of Medicine, Boston, Massachusetts.
authors.forename: Hiran C
authors.initials: HC
authors.lastname: Fernando
authors.affiliation: Department of Surgery, Division of Thoracic Surgery, Boston University School of Medicine, Boston, Massachusetts. Electronic address: virginia.litle@bmc.org.
authors.forename: Virginia R
authors.initials: VR
authors.lastname: Litle
mesh_terms: D000686:Amyloidosis / Q000175:diagnosis; D001402:B-Lymphocytes / Q000473:pathology; D002999:Clone Cells / Q000473:pathology; D003224:Congo Red; D003937:Diagnosis, Differential; D005260:Female; D015326:Gene Rearrangement, B-Lymphocyte, Heavy Chain; D006801:Humans; D007145:Immunoglobulin kappa-Chains / Q000097:blood; D008175:Lung Neoplasms / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D008875:Middle Aged; D008998:Monoclonal Gammopathy of Undetermined Significance / Q000150:complications* / Q000175:diagnosis / Q000473:pathology; D011013:Pneumonectomy / Q000379:methods*; D013194:Staining and Labeling; D014057:Tomography, X-Ray Computed
chemical_list: D007145:Immunoglobulin kappa-Chains; D003224:Congo Red