title: Management of massive diffuse alveolar hemorrhage in a child with systemic lupus erythematosus.
abstract: Diffuse alveolar hemorrhage (DAH) from systemic lupus erythematosus (SLE) is a rare but potentially life-threatening condition. We report the case of a 14-year-old female with SLE who developed hypoxia and shock secondary to severe alveolar hemorrhage. She was successfully managed by placement on extracorporeal membrane oxygenation (ECMO) followed by emergent pulmonary lobectomy and medical treatment including high-dose methylprednisolone, cyclophosphamide, intravenous immunoglobulin, and plasmapheresis.
authors.affiliation: Division of Pediatric Critical Care Medicine, Department of Pediatrics, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, TN Memphis, 38103 USA.
authors.forename: Dai
authors.initials: D
authors.lastname: Kimura
authors.affiliation: Division of Pediatric Critical Care Medicine, Department of Pediatrics, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, TN Memphis, 38103 USA ; Department of ECMO/Apheresis, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Samir
authors.initials: S
authors.lastname: Shah
authors.affiliation: Department of Cardiology, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Mario
authors.initials: M
authors.lastname: Briceno-Medina
authors.affiliation: Department of Cardiology, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Shyam
authors.initials: S
authors.lastname: Sathanandam
authors.affiliation: Department of Pulmonology, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Brent
authors.initials: B
authors.lastname: Haberman
authors.affiliation: Department of Pathology, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Department of Rheumatology, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Myers
authors.affiliation: Department of Cardiovascular Surgery, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Tk Susheel
authors.initials: TS
authors.lastname: Kumar
authors.affiliation: Department of Cardiovascular Surgery, Le Bonheur Children's Hospital/University of Tennessee Health Science Center, 50 N. Dunlap St, Memphis, TN USA.
authors.forename: Christopher
authors.initials: C
authors.lastname: Knott-Craig
keywords: Diffuse alveolar hemorrhage (DAH); Extracorporeal membrane oxygenation (ECMO); Hemoptysis; Lobectomy; Plasmapheresis; Systemic lupus erythematosus (SLE)