title: Skin, ear and testis--unusual sites of tuberculosis.
abstract: Pulmonary localization is the most common site of tuberculosis (TB)and the most contagious form. Extrapulmonary tuberculosis with the rarest and most unexpected localizations represents a significant proportion of all cases of tuberculosis and remains an important public health problem. We report three unusual TB locations: skin, ear and testis occurred in three immunocompetent patients. In the case of skin and testicular lesions, diagnosis was based on pathological confirmation of granulomas with caseous necrosis. In the third case the diagnosis was made possible by identification of positive Acid-Fast Bacilli smear and positive culture from othic drainage fluid. The outcome at all three patients was good with antituberculous treatment. These unusual localization of tuberculosis also highlight the possibility of extrapulmonary tuberculosis as a differential diagnosis in many common diseases.
authors.forename: Cătălina Elena
authors.initials: CE
authors.lastname: Ene
authors.forename: Claudia
authors.initials: C
authors.lastname: Toma
authors.forename: Ionela
authors.initials: I
authors.lastname: Belaconi
authors.forename: Stefan
authors.initials: S
authors.lastname: Dumitrache-Rujinski
authors.forename: Daniela
authors.initials: D
authors.lastname: Jipa
authors.forename: Adrian
authors.initials: A
authors.lastname: Tudor
authors.forename: Diana
authors.initials: D
authors.lastname: Leonte
authors.forename: Miron Alexandru
authors.initials: MA
authors.lastname: Bogdan
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use; D001706:Biopsy; D003937:Diagnosis, Differential; D004432:Ear, Middle; D005260:Female; D006225:Hand / Q000382:microbiology / Q000473:pathology; D006801:Humans; D008297:Male; D008417:Mastoiditis / Q000188:drug therapy / Q000382:microbiology*; D008875:Middle Aged; D009169:Mycobacterium tuberculosis / Q000302:isolation & purification*; D009919:Orchiectomy; D010035:Otitis Media, Suppurative / Q000188:drug therapy / Q000382:microbiology*; D035583:Rare Diseases; D012307:Risk Factors; D013492:Suppuration / Q000382:microbiology; D013733:Testicular Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery; D016896:Treatment Outcome; D014382:Tuberculosis, Cutaneous / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology*; D014389:Tuberculosis, Male Genital / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology* / Q000601:surgery
chemical_list: D000995:Antitubercular Agents