title: [A Case of Bacteremia Caused by Ochrobacterium intermedium].
abstract: We report herein on a case of bacteremia caused by Ochrobactrum intermedium (O. intermedium) identified with biotyper matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS). An 86-year-old man was admitted to our hospital with paralysis of the right side of the body and dysphagia. He was diagnosed as having a pontine infarction based on the brain MRI findings and was admitted to hospital to have anti-platelet therapy. Three days after admission, he had a fever. Although he had redness and swelling at the peripheral venous catheter insertion site, he was diagnosed as having aspiration pneumonia, since he had fine crackles on auscultation. Soon after taking two sets of blood cultures and removal of the peripheral venous catheter, sulbactam/ampicillin (SBT/ABPC) was administrated. Fifty three hours after incubation, gram-negative bacilli was detected from an aerobic bottle and identified as O. intermedium with MALDI-TOF MS (Bruker MS). Antimicrobial chemotherapy was changed to meropenem (MEPM). He was treated for a total of seven days, and recovered without relapse. Infection caused by O. intermedium has been very uncommon, however, O. intermedium has been recognized as an emerging pathogen in immunodeficient and immunocompetent patients. Since identification of Ochrobactrum species by biochemical methods could be difficult, MALDI-TOF MS might be helpful to clarify Ochrobactrum species just as in the present case.
authors.forename: Jun
authors.initials: J
authors.lastname: Hirai
authors.forename: Yuka
authors.initials: Y
authors.lastname: Yamagishi
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sakanashi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Koizumi
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Suematsu
authors.forename: Hiroshige
authors.initials: H
authors.lastname: Mikamo
mesh_terms: D000369:Aged, 80 and over; D016470:Bacteremia / Q000209:etiology*; D016905:Gram-Negative Bacterial Infections / Q000175:diagnosis; D006801:Humans; D008297:Male; D042041:Ochrobactrum