title: Incidence, mortality, and prevalence of end-stage chronic renal disease in the Bajo Lempa region of El Salvador: A ten-year community registry.
abstract: The Bajo Lempa is an impoverished rural coastal region of El Salvador affected by the chronic kidney disease (CKD) epidemic known as Mesoamerican nephropathy. The local community organisation Fondo Social de Emergencia para la Salud (FSES) (Emergency social fund for health) is helping to fight the epidemic in 42 communities of the region (19,223 inhabitants; average age 26.7 years; 48.5% male; 40.2% <18 years).
  
  
  OBJECTIVE
  To report annual rates of end-stage renal disease (ESRD) incidence and patient mortality in these communities during a 10-year period (2004-2013), and the prevalence of patients receiving renal replacement therapy (RRT) as of 31 December 2013.
  
  
  METHODS
  The FSES recorded new ESRD cases, basic patient history, form of RRT if received and patient deaths.
  
  
  RESULTS
  We registered 271 new ESRD cases (annual average 27.1; 89% male; average age 55.6 years, four <18 years). Average annual ESRD incidence rate: 1409.8 per million population (pmp). Two-thirds did not report diabetes or hypertension. 94 patients (34.7%) received RRT: 58 in the Ministry of health, 26 in private services, 9 in social security and 1 in the military health system. 246 patients died (annual average 24.6 deaths; 89.4% male; average age 56.1 years; 92.3% at home). Average annual mortality rate: 128/100,000 population. Prevalence of patients receiving RRT in 2013: 1300.5 pmp (N=25; 84% male; average age 51 years).
  
  
  CONCLUSIONS
  This region has a high incidence of ESRD. Few receive RRT. Patient mortality is high even with RRT. Most patients are male (9:1). Social determinants influence the high mortality.
authors.affiliation: Comité científico, Departamento de Investigación, Hospital Nacional Rosales, San Salvador, El Salvador; Fondo Social de Emergencia para la Salud, Cantón Tierra Blanca, Usulután, El Salvador. Electronic address: rgt@anhaes.org.
authors.forename: Ramón
authors.initials: R
authors.lastname: García-Trabanino
authors.affiliation: Fondo Social de Emergencia para la Salud, Cantón Tierra Blanca, Usulután, El Salvador; Sistema Básico de Salud Integral (SIBASI), Usulután, Ministerio de Salud, El Salvador.
authors.forename: Carolina
authors.initials: C
authors.lastname: Hernández
authors.affiliation: Fondo Social de Emergencia para la Salud, Cantón Tierra Blanca, Usulután, El Salvador; Unidad médica Puerto El Triunfo, Instituto Salvadoreño del Seguro Social (ISSS), Usulután, El Salvador.
authors.forename: Adrián
authors.initials: A
authors.lastname: Rosa
authors.affiliation: Fondo Social de Emergencia para la Salud, Cantón Tierra Blanca, Usulután, El Salvador; Atención Primaria, Área Sanitaria Jaén Nordeste, Jaén, Andalucía, España.
authors.forename: Jesús
authors.initials: J
authors.lastname: Domínguez Alonso
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004544:El Salvador / Q000453:epidemiology; D005260:Female; D006801:Humans; D015994:Incidence; D007676:Kidney Failure, Chronic / Q000401:mortality*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012042:Registries; D017582:Renal Replacement Therapy; D055815:Young Adult
keywords: Bajo Lempa; Chronic kidney disease; El Salvador; End-stage renal disease; Enfermedad renal crónica; Enfermedad renal crónica terminal; Incidence; Incidencia; Mesoamerican nephropathy; Mortalidad; Mortality; Nefropatía mesoamericana; Prevalence; Prevalencia; Renal replacement therapy; Tratamiento sustitutivo renal