title: [Dyslipidaemia and atherogenic risk in patients with systemic lupus erythematosus].
abstract: BACKGROUND
  Dyslipidaemia is a common comorbidity in patients with systemic lupus erythematosus.
  
  
  METHODS
  Fifty-one patients were included. Variables associated with the disease and the drugs used were recorded. Atherogenic risk was calculated. Chi square was used for categorical variables. ANOVA was performed and a logistic regression model to determine the association of the variables with the presence of dyslipidaemia.
  
  
  RESULTS
  A percentage of 68.6 had dyslipidaemia. A significant difference between the presence of dyslipidaemia and activity index measured by SLEDAI was found, the presence of lupus nephritis, use of prednisone≥20mg/day, evolution of the disease<3 years. Significance between the absence of dyslipidaemia and use of hydroxychloroquine was found. SLEDAI≥4 and the use of prednisone≥20mg/day were independently associated with the presence of dyslipidaemia. The average of Castelli rate was 5.02, the Kannel index was 2.97 and triglyceride/HDL-C ratio was 5.24.
  
  
  CONCLUSIONS
  Patients with systemic lupus erythematosus have a high prevalence of dyslipidaemia and a high atherogenic rate, which increases cardiovascular risk significantly.
authors.affiliation: Residente de tercer año de Medicina Interna, Hospital Regional de Alta Especialidad Dr. Gustavo A. Rovirosa Pérez, Villahermosa , Tabasco, México. Electronic address: antonio_bg1986@hotmail.com.
authors.forename: José Antonio de Jesús
authors.initials: JA
authors.lastname: Batún Garrido
authors.affiliation: Residente de tercer año de Medicina Interna, Hospital Regional de Alta Especialidad Dr. Gustavo A. Rovirosa Pérez, Villahermosa , Tabasco, México.
authors.forename: Hugo Alberto
authors.initials: HA
authors.lastname: Radillo Alba
authors.affiliation: Médico Internista y Reumatólogo, Hospital Regional de Alta Especialidad Dr. Gustavo A. Rovirosa Pérez, Villahermosa, Tabasco, México.
authors.forename: Éufrates
authors.initials: É
authors.lastname: Hernández Núñez
authors.affiliation: Médico Internista y Reumatólogo, Hospital Regional de Alta Especialidad Dr. Gustavo A. Rovirosa Pérez, Villahermosa, Tabasco, México.
authors.forename: Francisco
authors.initials: F
authors.lastname: Olán
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D050197:Atherosclerosis / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D003430:Cross-Sectional Studies; D050171:Dyslipidemias / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D005260:Female; D006305:Health Status Indicators; D006801:Humans; D016015:Logistic Models; D008180:Lupus Erythematosus, Systemic / Q000150:complications*; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies; D018570:Risk Assessment; D012307:Risk Factors
keywords: Atherogenic index; Dislipidemia; Dyslipidaemia; Lupus eritematoso sistémico; Systemic lupus erythematosus; Índice aterogénico