title: The use of engineered protein materials in electrochemical devices.
abstract: Bioelectrochemical technologies have an important and growing role in healthcare, with applications in sensing and diagnostics, as well as the potential to be used as implantable power sources and be integrated with automated drug delivery systems. Challenges associated with enzyme-based electrodes include low current density and short functional lifetimes. Protein engineering is emerging as a powerful tool to overcome these issues. By taking advantage of the ability to precisely define protein sequences, electrodes can be organized into high performing structures, and enable the next generation of medical devices.
authors.affiliation: Department of Chemical & Biomolecular Engineering, Case Western Reserve University, Cleveland, OH 44106, USA julie.renner@case.edu.
authors.forename: Julie N
authors.initials: JN
authors.lastname: Renner
authors.affiliation: Department of Chemistry, University of Utah, Salt Lake City, UT 84112, USA.
authors.forename: Shelley D
authors.initials: SD
authors.lastname: Minteer
mesh_terms: D055664:Electrochemical Techniques / Q000295:instrumentation*; D004566:Electrodes; D004867:Equipment Design; D015202:Protein Engineering / Q000379:methods*; D011506:Proteins / Q000737:chemistry
chemical_list: D011506:Proteins
keywords: Protein engineering; biocatalysts; bioelectrocatalysis; bioelectrodes; electrochemical biosensors; enzymatic biofuel cell