title: Prevalence and management of recurrent respiratory papillomatosis (RRP) in the UK: cross-sectional study.
abstract: OBJECTIVE
  To estimate the number of patients with recurrent respiratory papillomatosis currently managed in secondary and tertiary health care in the UK and the frequency of its treatment with radiofrequency cold ablation (Coblation™).
  
  
  METHODS
  Cross-sectional survey of ENT consultants in the UK with validation using Hospital Episode Statistics (HES) inpatient data.
  
  
  METHODS
  Online survey.
  
  
  METHODS
  ENT consultants in the UK.
  
  
  METHODS
  Number of recurrent respiratory papillomatosis patients currently managed in acute care in the UK and frequency of use of Coblation.
  
  
  RESULTS
  A total of 283 ENT consultants from 128 UK NHS healthcare trusts and health boards completed the online survey. Responses were received from 86% of surveyed organisations, and an estimated 45% of all ENT consultants in UK. The estimated number of recurrent respiratory papillomatosis patients from the cross-sectional survey was 918 (at August 2015) which included 730 patients in England. The number of recurrent respiratory papillomatosis patients in England estimated from Hospital Episode Statistics (2014/15 financial year) was up to 741. A total of 42 Coblation procedures conducted in the UK were identified from the cross-sectional survey; 36 were conducted in England compared with 34 identified from Hospital Episode Statistics.
  
  
  CONCLUSIONS
  The numbers of recurrent respiratory papillomatosis patients and Coblation procedures identified in England from a cross-sectional survey and Hospital Episode Statistics were in broad agreement. Our study estimated 1.42 recurrent respiratory papillomatosis patients per 100 000 in the general UK population. We also estimated that Coblation procedures accounted for 3% of interventional treatments conducted in the UK recurrent respiratory papillomatosis population.
authors.affiliation: Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Donne
authors.affiliation: Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.|Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: K
authors.initials: K
authors.lastname: Keltie
authors.affiliation: Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
authors.forename: H
authors.initials: H
authors.lastname: Cole
authors.affiliation: Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.|Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
authors.forename: A J
authors.initials: AJ
authors.lastname: Sims
authors.affiliation: National Institute for Health and Care Excellence, London, UK.
authors.forename: H
authors.initials: H
authors.lastname: Patrick
authors.affiliation: Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, UK.
authors.forename: S
authors.initials: S
authors.lastname: Powell
mesh_terms: D000328:Adult; D017115:Catheter Ablation / Q000706:statistics & numerical data*; D002648:Child; D003430:Cross-Sectional Studies; D003452:Cryosurgery / Q000706:statistics & numerical data*; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D030361:Papillomavirus Infections / Q000453:epidemiology* / Q000601:surgery*; D010818:Practice Patterns, Physicians'; D015995:Prevalence; D012141:Respiratory Tract Infections / Q000453:epidemiology* / Q000601:surgery*; D006113:United Kingdom / Q000453:epidemiology