title: [Evaluation of liver function between indoor and outdoor workers: preliminary results].
abstract: BACKGROUND
  The aim of our study is to compare liver damage in "outdoor" environment technicians, a category occupationally exposed, and in "indoor" workers.
  
  
  METHODS
  We studied 142 male technicians of the environment exposed to urban pollution and 142 male "indoor" workers not exposed. We compared mean and standard deviation of the following liver parameters: glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase (GPT), gamma-glutamyl-traspeptidasi (γGT) and alkaline phosphatase (PHA), total bilirubin (TB) and direct (DB). We made the two groups comparable for age, length of service, BMI, alcohol consumption and smoking habits, and excluded the workers who presented confounding factors.
  
  
  RESULTS
  We found statistically significant differences about the levels of γGT, PHA, GPT and albumin between the "outdoor" workers exposed and the "indoor" control group. In the outdoor group we observed statistically significant values, GPT (51.8 ± 30.6 I.U./l vs. 30 ± 22.3 I.U./l; p = 0.000), γ-GT (42.2 ± 29.4 I.U./l vs. 22.4 ± 20.7 I.U./l; p = 0.000) and PHA (75.7 ± 20.6 I.U./l vs. 59.1 ± 19.6 I.U./l; p= 0.000) compared to the unexposed group. No statistically significant difference emerged between the averages for the values of GOT (25.3 ± 20.7 I.U./l vs. 26 ± 17.7 I.U./l; p = 0.736) in two groups.
  
  
  CONCLUSIONS
  It clearly emerges that the contaminants may alter the values of liver tests after prolonged exposure.
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: F
authors.initials: F
authors.lastname: Tomei
authors.affiliation: Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Università "Sapienza"
authors.forename: S
authors.initials: S
authors.lastname: Ricci
authors.affiliation: Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Unità di Medicina del Lavoro, Università "Sapienza", Roma.
authors.forename: F
authors.initials: F
authors.lastname: De Marco
authors.affiliation: Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Unità di Medicina del Lavoro, Università "Sapienza", Roma.
authors.forename: C
authors.initials: C
authors.lastname: Sacco
authors.affiliation: Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Università "Sapienza"
authors.forename: P
authors.initials: P
authors.lastname: Ricci
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: B
authors.initials: B
authors.lastname: Pimpinella
authors.affiliation: Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Unità di Medicina del Lavoro, Università "Sapienza", Roma.
authors.forename: B
authors.initials: B
authors.lastname: Scala
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: S
authors.initials: S
authors.lastname: Corsale
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: R
authors.initials: R
authors.lastname: Massimi
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: T
authors.initials: T
authors.lastname: Caciari
authors.affiliation: Dipartimento di Sanità Pubblica e Malattie Infettive, Università "Sapienza", Roma.
authors.forename: V
authors.initials: V
authors.lastname: Anzelmo
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: A
authors.initials: A
authors.lastname: Sancini
authors.affiliation: Spin off "Sipro" Università "Sapienza", Roma.
authors.forename: T
authors.initials: T
authors.lastname: Casale
authors.affiliation: Istituto di Sanità Pubblica, Unità di Medicina del Lavoro, Università di Roma "Cattolica del Sacro Cuore"
authors.forename: G
authors.initials: G
authors.lastname: Tomei
authors.affiliation: Dipartimento di Scienze Anatomiche, Istologiche, Medico Legali e dell'Apparato Locomotore, Unità di Medicina del Lavoro, Università "Sapienza", Roma.
authors.forename: M V
authors.initials: MV
authors.lastname: Rosati
mesh_terms: D000328:Adult; D000367:Age Factors; D000410:Alanine Transaminase / Q000097:blood; D000428:Alcohol Drinking / Q000453:epidemiology; D000469:Alkaline Phosphatase / Q000097:blood; D001219:Aspartate Aminotransferases / Q000097:blood; D001663:Bilirubin / Q000097:blood; D015992:Body Mass Index; D056486:Chemical and Drug Induced Liver Injury / Q000097:blood / Q000453:epidemiology*; D006801:Humans; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D012907:Smoking / Q000453:epidemiology; D013997:Time Factors; D014505:Urban Population; D005723:gamma-Glutamyltransferase / Q000097:blood
chemical_list: D005723:gamma-Glutamyltransferase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D000469:Alkaline Phosphatase; D001663:Bilirubin
keywords: Air pollution; Liver; Liver enzymes; Particulate matter; Workers "indoor"; Workers "outdoor"