title: Study of fatigue, depression, and associated factors in type 2 diabetes mellitus in industrial workers.
abstract: BACKGROUND
  Type 2 diabetes mellitus is a significant health problem and imposes great physical, financial and psychological burden among the affected population. Among people with diabetes, fatigue is a pervasive and distressing complaint, which is further accentuated by presence of depression.
  
  
  OBJECTIVE
  To assess the prevalence of fatigue and depression and associated clinical and socio demographic correlates in type 2diabetes.
  
  
  METHODS
  This cross sectional study included 100 patients of diabetes type 2 and equal number of healthy controls between the ages of 18 to 70 years. A detailed evaluation of socio demographic and clinical parameters was made. Participants were also assessed for presence of depression and fatigue using PHQ-9 and Fatigue Severity Scale(FSS)respectively.
  
  
  RESULTS
  Fatigue and depression was found in 68 % and 53 % of diabetic participants. Diabetic patients were 10.37 times and 4.80 times more likely to suffer from fatigue and depression respectively. Both fatigue and depression were found to be significantly associated with duration of illness, fasting and post prandial blood glucose level, diabetic complications and Body Mass Index (BMI). Fatigue was also strongly correlated with depression in study sample.
  
  
  CONCLUSIONS
  Fatigue and depression are reasonably correlated with type 2 diabetes. Various clinical parameters of diabetes are strongly associated with both fatigue and depression. Fatigue itself has significant correlation with depression in type 2 diabetes. Regular monitoring of biochemical parameters are paramount to predict the development of fatigue and depression in type 2 diabetes.
authors.affiliation: Department of Psychiatry, ESIC Model Hospital, Jaipur, Rajasthan, India.
authors.forename: Akhilesh
authors.initials: A
authors.lastname: Jain
authors.affiliation: Department of Ophthalmology, ESIC Model Hospital, Jaipur, Rajasthan, India.
authors.forename: Rekha
authors.initials: R
authors.lastname: Sharma
authors.affiliation: Department of Medicine, ESIC Model Hospital, Jaipur, Rajasthan, India.
authors.forename: Pavan Kumar
authors.initials: PK
authors.lastname: Choudhary
authors.affiliation: Department of Medicine, ESIC Model Hospital, Jaipur, Rajasthan, India.
authors.forename: Neelam
authors.initials: N
authors.lastname: Yadav
authors.affiliation: Department of Medicine, ESIC Model Hospital, Jaipur, Rajasthan, India.
authors.forename: Garima
authors.initials: G
authors.lastname: Jain
authors.affiliation: Department of Psychiatry, ESIC Model Hospital, Jaipur, Rajasthan, India.
authors.forename: Mukesh
authors.initials: M
authors.lastname: Maanju
keywords: Depression; diabetes mellitus; fatigue