title: [Identification of Psychotropic Drugs Attributed to Fatal Overdose--A Case-control Study by Data from the Tokyo Medical Examiner's Office and Prescriptions].
abstract: Drug overdose is a serious public health issue and fatal cases have been reported from various fields of medicine. This case-control analysis assessed the comparison between fatal overdose cases in the special wards of Tokyo Metropolitan area and prescribed psychotropic drugs in Tokyo in 2009-2010. It was suggested that the prescribed drugs serve as a direct cause of death in overdose cases. Furthermore, pentobarbital calcium, chlorpromazine-promethazine-phenobarbital, levomepromazine and flunitrazepam were identified as drugs with a high risk of fatal overdose. It is encouraged to prudently verify the intended application and usage of such psychotropic drugs in each case upon their prescription. This is the first study in Japan to identify psychotropic drugs with a high risk of fatal overdose by case-control study.
authors.forename: Wakako
authors.initials: W
authors.lastname: Hikiji
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Okumura
authors.forename: Toshihiko
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Takanobu
authors.initials: T
authors.lastname: Tanifuji
authors.forename: Hideto
authors.initials: H
authors.lastname: Suzuki
authors.forename: Tadashi
authors.initials: T
authors.lastname: Takeshima
authors.forename: Tatsushige
authors.initials: T
authors.lastname: Fukunaga
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003334:Coroners and Medical Examiners; D062787:Drug Overdose / Q000401:mortality; D011307:Drug Prescriptions; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011619:Psychotropic Drugs / Q000506:poisoning*; D012307:Risk Factors; D014041:Tokyo; D055815:Young Adult
chemical_list: D011619:Psychotropic Drugs