title: Simultaneous separation/enrichment and detection of trace ciprofloxacin and lomefloxacin in food samples using thermosensitive smart polymers aqueous two-phase flotation system combined with HPLC.
abstract: Smart polymer aqueous two phase flotation system (SPATPF) is a new separation and enrichment technology that integrated the advantages of the three technologies, i.e., aqueous two phase system, smart polymer and flotation sublation. Ethylene oxide and propylene oxide copolymer (EOPO)-(NH4)2SO4 SPATPF is a pretreatment technique, and it is coupled with high-performance liquid chromatography to analyze the trace ciprofloxacin and lomefloxacin in real food samples. The optimized conditions of experiment were determined in the multi-factor experiment by using response surface methodology. The flotation efficiency of lomefloxacin and ciprofloxacin was 94.50% and 98.23% under the optimized conditions. The recycling experimentsshowed that the smart polymer EOPO could use repeatedly, which will reduce the cost in the future application.
authors.affiliation: Laboratory of Functional Materials Physics and Chemistry, Jilin Normal University, 1301 Haifeng Street, Siping 136000, China; School of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Lu
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Chen
authors.affiliation: Laboratory of Functional Materials Physics and Chemistry, Jilin Normal University, 1301 Haifeng Street, Siping 136000, China.
authors.forename: Miao
authors.initials: M
authors.lastname: Yu
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Han
authors.affiliation: School of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Laboratory of Functional Materials Physics and Chemistry, Jilin Normal University, 1301 Haifeng Street, Siping 136000, China.
authors.forename: Zhenjiang
authors.initials: Z
authors.lastname: Tan
authors.affiliation: Laboratory of Functional Materials Physics and Chemistry, Jilin Normal University, 1301 Haifeng Street, Siping 136000, China; School of Chemistry and Chemical Engineering, Jiangsu University, 301 Xuefu Road, Zhenjiang 212013, China. Electronic address: yongshengyanjs@126.com.
authors.forename: Yongsheng
authors.initials: Y
authors.lastname: Yan
mesh_terms: D002851:Chromatography, High Pressure Liquid / Q000379:methods; D002939:Ciprofloxacin / Q000032:analysis*; D024841:Fluoroquinolones / Q000032:analysis*; D005502:Food; D005504:Food Analysis; D011108:Polymers / Q000737:chemistry
chemical_list: D024841:Fluoroquinolones; D011108:Polymers; D002939:Ciprofloxacin; C053091:lomefloxacin
keywords: Ciprofloxacin hydrochloride; Determination; Lomefloxacin; Recycling; Smart polymer aqueous two phase flotation system