title: Spontaneous Coronary Artery Dissection.
abstract: Spontaneous coronary artery dissection is an important etiology of nonatherosclerotic acute coronary syndrome, myocardial infarction, and sudden death. Innovations in the catheterization laboratory including optical coherence tomography and intravascular ultrasound have enhanced the ability to visualize intimal disruption and intramural hematoma associated with SCAD. Formerly considered "rare," these technological advances and heightened awareness suggest that SCAD is more prevalent than prior estimates. SCAD is associated with female sex, young age, extreme emotional stress, or extreme exertion, pregnancy, and fibromuscular dysplasia. The clinical characteristics and management strategies of SCAD patients are different than for atherosclerotic heart disease and deserve specific consideration. This review will highlight recent discoveries about SCAD as well as describe current efforts to elucidate remaining gaps in knowledge.
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA. tweet.marysia@mayo.edu.
authors.forename: Marysia S
authors.initials: MS
authors.lastname: Tweet
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Gulati
authors.affiliation: Department of Internal Medicine, Division of Cardiovascular Diseases, Mayo Clinic, 200 1st Street SW, Rochester, MN, 55905, USA.
authors.forename: Sharonne N
authors.initials: SN
authors.lastname: Hayes
mesh_terms: D054058:Acute Coronary Syndrome / Q000209:etiology; D000208:Acute Disease; D017023:Coronary Angiography; D003330:Coronary Vessel Anomalies / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy*; D005260:Female; D005352:Fibromuscular Dysplasia / Q000150:complications; D006801:Humans; D011247:Pregnancy; D011249:Pregnancy Complications, Cardiovascular / Q000000981:diagnostic imaging / Q000628:therapy; D014652:Vascular Diseases / Q000150:complications / Q000151:congenital* / Q000000981:diagnostic imaging / Q000628:therapy
keywords: Acute coronary syndrome; Fibromuscular dysplasia; Myocardial infarction; Pregnancy; Spontaneous coronary artery dissection; Women