title: Magnetic resonance angiography of fetal vasculature at 3.0 T.
abstract: Magnetic resonance angiography has not been used much previously for visualizing fetal vessels in utero for reasons that include a contraindication for the use of exogenous contrast agents, maternal respiratory motion and fetal motion. In this work, we report the feasibility of using an appropriately modified clinical time-of-flight magnetic resonance imaging sequence for non-contrast angiography of human fetal and placental vessels at 3.0 T. Using this 2D angiography technique, it is possible to visualize fetal vascular networks in late pregnancy.
  
  
  CONCLUSIONS
  • 3D-visualization of fetal vasculature is feasible using non-contrast MRA at 3.0 T. • Visualization of placental vasculature is also possible with this method. • Fetal MRA can serve as a vascular localizer for quantitative MRI studies. • This method can be extended to 1.5 T.
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA. jneelava@med.wayne.edu.|Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA. jneelava@med.wayne.edu.
authors.forename: Jaladhar
authors.initials: J
authors.lastname: Neelavalli
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.|Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA.
authors.forename: Uday
authors.initials: U
authors.lastname: Krishnamurthy
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.
authors.forename: Pavan K
authors.initials: PK
authors.lastname: Jella
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.|Department of Radiology, Children's Hospital of Michigan, Detroit, MI, USA.
authors.forename: Swati S
authors.initials: SS
authors.lastname: Mody
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.|Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA.
authors.forename: Brijesh K
authors.initials: BK
authors.lastname: Yadav
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.
authors.forename: Kelly
authors.initials: K
authors.lastname: Hendershot
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA.|Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, and Detroit, MI, USA.
authors.forename: Edgar
authors.initials: E
authors.lastname: Hernandez-Andrade
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA.|Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, and Detroit, MI, USA.
authors.forename: Lami
authors.initials: L
authors.lastname: Yeo
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.
authors.forename: Maria D
authors.initials: MD
authors.lastname: Cabrera
authors.affiliation: Department of Radiology, Wayne State University School of Medicine, 4201 St. Antoine, Detroit, MI, 48201, USA.|Department of Biomedical Engineering, Wayne State University, Detroit, MI, USA.
authors.forename: Ewart M
authors.initials: EM
authors.lastname: Haacke
authors.affiliation: Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA.|Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, and Detroit, MI, USA.
authors.forename: Sonia S
authors.initials: SS
authors.lastname: Hassan
authors.affiliation: Perinatology Research Branch, NICHD/NIH/DHHS, Bethesda, MD, and Detroit, MI, USA.|Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI, USA.|Department of Epidemiology and Biostatistics, Michigan State University, East Lansing, MI, USA.|Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA.
authors.forename: Roberto
authors.initials: R
authors.lastname: Romero
mesh_terms: D001783:Blood Flow Velocity; D001808:Blood Vessels / Q000196:embryology*; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D005333:Fetus / Q000098:blood supply / Q000000981:diagnostic imaging*; D006801:Humans; D018810:Magnetic Resonance Angiography / Q000379:methods*; D010920:Placenta / Q000098:blood supply / Q000000981:diagnostic imaging; D011247:Pregnancy; D014652:Vascular Diseases / Q000000981:diagnostic imaging
chemical_list: D003287:Contrast Media
keywords: Fetal circulation; Non-contrast magnetic resonance angiography; Placental vasculature; Pseudo-triggering; Time of flight vascular imaging