title: The histological variants of liposarcoma: predictive MRI findings with prognostic implications, management, follow-up, and differential diagnosis.
abstract: Liposarcoma is the single most common soft tissue sarcoma accounting for up to 35 % of sarcomas. It represents a histologically diverse group of soft tissue tumors that demonstrate a wide range of imaging appearances with varied behavior patterns. Correspondingly, more aggressive histological subtypes often require management that includes a combination of surgery, chemotherapy, and radiation therapy. Distinguishing among liposarcoma subtypes has important therapeutic and prognostic implications. In this manuscript, we review the liposarcoma subtypes and their histologic and MRI findings, prognostic implications, and differential diagnostic considerations.
authors.affiliation: Department of Radiology, Mount Sinai Medical Center, Miami Beach, FL, USA. magdarizer@gmail.com.
authors.forename: Magda
authors.initials: M
authors.lastname: Rizer
authors.affiliation: Department of Radiology and Imaging Sciences, Section of Musculoskeletal Imaging, Emory Healthcare, Atlanta, GA, USA.
authors.forename: Adam D
authors.initials: AD
authors.lastname: Singer
authors.affiliation: Bone and Soft Tissue Pathology, Department of Pathology, Emory Healthcare, Atlanta, GA, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Edgar
authors.affiliation: Section of Musculoskeletal Imaging, Miller School of Medicine, University of Miami, Miami, FL, USA.
authors.forename: Jean
authors.initials: J
authors.lastname: Jose
authors.affiliation: Section of Musculoskeletal Imaging, Miller School of Medicine, University of Miami, Miami, FL, USA.
authors.forename: Ty K
authors.initials: TK
authors.lastname: Subhawong
mesh_terms: D003937:Diagnosis, Differential; D005500:Follow-Up Studies; D006801:Humans; D008080:Liposarcoma / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy*; D008279:Magnetic Resonance Imaging; D011379:Prognosis
keywords: Atypical lipomatous tumor; Follow-up; Liposarcoma; MRI; Management; Surveillance