title: One-pot aqueous synthesis of gadolinium doped CdTe quantum dots with dual imaging modalities.
abstract: A facile one-pot strategy has been developed for the aqueous synthesis of Gd doped CdTe (Gd:CdTe) QDs as fluorescence and magnetic resonance imaging dual-modal agent. The prepared Gd:CdTe QDs showed narrow size distribution and the average size was less than 5nm. The amount of Gd(3+) dopant in Gd:CdTe QDs significantly affected the optical properties of obtained QDs. The highest PL QY for the prepared Gd:CdTe QDs was up to 42.5%. The QDs showed the weak toxicity and significant enhancement in MRI signal. The specific relaxivity value (r1) was determined to be 4.22mM(-1)s(-1). These properties make the prepared Gd:CdTe QDs be an effective dual-modal imaging agent and have great potential applications in biomedical field.
authors.affiliation: Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China.
authors.forename: Chunli
authors.initials: C
authors.lastname: Jiang
authors.affiliation: College of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, PR China.
authors.forename: Zhitao
authors.initials: Z
authors.lastname: Shen
authors.affiliation: Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China.
authors.forename: Chunhua
authors.initials: C
authors.lastname: Luo
authors.affiliation: Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China.
authors.forename: Hechun
authors.initials: H
authors.lastname: Lin
authors.affiliation: Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China.
authors.forename: Rong
authors.initials: R
authors.lastname: Huang
authors.affiliation: College of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, PR China.
authors.forename: Yiting
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Key Laboratory of Polar Materials and Devices, Ministry of Education, East China Normal University, Shanghai 200241, PR China. Electronic address: hpeng@ee.ecnu.edu.cn.
authors.forename: Hui
authors.initials: H
authors.lastname: Peng
mesh_terms: D018938:Caco-2 Cells; D019187:Cadmium Compounds / Q000737:chemistry*; D060326:Chemistry Techniques, Synthetic; D005682:Gadolinium / Q000737:chemistry*; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D061848:Optical Imaging / Q000379:methods*; D045663:Quantum Dots / Q000737:chemistry* / Q000633:toxicity; D013691:Tellurium / Q000737:chemistry*; D014867:Water / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D014867:Water; D005682:Gadolinium; D013691:Tellurium; C028337:cadmium telluride
keywords: Aqueous synthesis; Fluorescence; Gd doped CdTe; MR imaging; Quantum dots