title: Choroid plexus papilloma in a beluga whale (Delphinapterus leucas).
abstract: We report herein a choroid plexus papilloma in a beluga whale (Delphinapterus leucas). This case was positive for choroid plexus tumor marker Kir7.1 on immunohistochemistry. These results and the high conservation of Kir7.1 across species at the amino acid sequence level strongly suggest that antibodies directed against Kir7.1 not only can be employed for the diagnosis of choroid plexus tumors in cetaceans, but are also likely to be diagnostically useful in other animal species.
authors.affiliation: Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau).
authors.forename: Christian
authors.initials: C
authors.lastname: Thomas
authors.affiliation: Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau).
authors.forename: June
authors.initials: J
authors.lastname: Mergl
authors.affiliation: Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau).
authors.forename: Erica
authors.initials: E
authors.lastname: Gehring
authors.affiliation: Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau).
authors.forename: Werner
authors.initials: W
authors.lastname: Paulus
authors.affiliation: Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau).
authors.forename: Daniel
authors.initials: D
authors.lastname: Martineau
authors.affiliation: Institute of Neuropathology, University Hospital Münster, Münster, Germany (Thomas, Paulus, Hasselblatt)Niagara Falls Animal Medical Centre, Niagara Falls, Ontario, Canada (Mergl, Gehring)Département de Pathologie et Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Montreal, Quebec, Canada (Martineau) hasselblatt@uni-muenster.de.
authors.forename: Martin
authors.initials: M
authors.lastname: Hasselblatt
mesh_terms: D000818:Animals; D000836:Animals, Zoo; D000912:Antibodies, Neoplasm / Q000276:immunology*; D050643:Beluga Whale; D005260:Female; D007150:Immunohistochemistry / Q000662:veterinary; D020288:Papilloma, Choroid Plexus / Q000175:diagnosis / Q000276:immunology / Q000662:veterinary*; D024661:Potassium Channels, Inwardly Rectifying / Q000276:immunology*
chemical_list: D000912:Antibodies, Neoplasm; C086989:KCNJ1 protein, human; D024661:Potassium Channels, Inwardly Rectifying
keywords: Beluga whales; Cetacea; Odontoceti; choroid plexus tumor; inwardly rectifying potassium channel Kir7.1; veterinary neuropathology