title: Enhanced Bone Bonding to Nanotextured Implant Surfaces at a Short Healing Period: A Biomechanical Tensile Testing in the Rat Femur.
abstract: OBJECTIVE
  To compare the bone bonding capabilities of 2 different surface treatments at an early healing period. Titanium alloy (Ti6Al4V) custom-made rectangular plates (1.4 × 2.4 × 4 mm) were either dual acid etched (Ti6Al4V-DAE) or DAE/nanotextured blasted (Ti6Al4V-NTB).
  
  
  METHODS
  Implants were placed in the distal femurs of 10 Wistar rats and were allowed to heal for 9 days. After euthanasia, the bone immediately proximal and distal to the implant was removed to test the bone bonding force with a universal testing machine. Ultrastructure of the bone/implant interface was assessed by scanning electron microscopy.
  
  
  RESULTS
  Ti6Al4V-NTB samples exhibited significantly greater bond strength than Ti6Al4V-DAE samples. Morphologically, the Ti6Al4V-NTB surfaces presented intimate interaction with bone, whereas little interaction between the Ti6Al4V-DAE surface and bone was observed.
  
  
  CONCLUSIONS
  The results of this study indicated a significant increase in bone bonding for the DAE/nanotextured blasted surface, which is suggested to be the outcome of the nanotexturing.
authors.affiliation: *Associate Professor, Biomaterials and Biomimetics and Director for Research, Department of Periodontology and Implant Dentistry, New York University College of Dentistry, NY. †Professor, Department of Prevention and Oral Rehabilitation, Federal University of Goias School of Dentistry, Goiania, GO, Brazil. ‡Researcher, Biomaterials and Biomimetics and Director for Research, Department of Periodontology and Implant Dentistry, New York University College of Dentistry, NY. §Professor, Department of Anatomy, University of Sao Paulo, Sao Paulo, Brazil. ¶Assistant Professor, Department of Oral Implantology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey. ‖Researcher, Department of Biomaterials and Biomimetics, New York University College of Dentistry, NY. #Associate Professor, Department of Prosthodontics, Faculty of Odontology, Malmö University, Malmö, Sweden.
authors.forename: Paulo G
authors.initials: PG
authors.lastname: Coelho
authors.forename: Ricardo A
authors.initials: RA
authors.lastname: Zavanelli
authors.forename: Marcos B
authors.initials: MB
authors.lastname: Salles
authors.forename: Sinem
authors.initials: S
authors.lastname: Yeniyol
authors.forename: Nick
authors.initials: N
authors.lastname: Tovar
authors.forename: Ryo
authors.initials: R
authors.lastname: Jimbo
mesh_terms: D000134:Acid Etching, Dental / Q000379:methods; D000497:Alloys; D000818:Animals; D001840:Dental Bonding / Q000379:methods*; D003757:Dental Implantation / Q000379:methods*; D005269:Femur / Q000601:surgery; D008297:Male; D036103:Nanotechnology / Q000379:methods; D016348:Osseointegration; D051381:Rats; D017208:Rats, Wistar; D013499:Surface Properties; D013718:Tensile Strength; D014025:Titanium / Q000627:therapeutic use
chemical_list: D000497:Alloys; C031462:titanium alloy (TiAl6V4); D014025:Titanium