title: Structural characterization of the lipoteichoic acid isolated from Staphylococcus sciuri W620.
abstract: Lipoteichoic acid (LTA) is an important cell envelope compound of Gram-positive bacteria. LTA isolated from allergy-protective Staphylococcus sciuri W620 strain was characterized by chemical analyses as well as 1D and 2D NMR experiments. Compositional analyses indicated the presence of glycerol (Gro), phosphate-Gro, alanine-Gro, glucose (Glc) and fatty acids. The studied strain produced LTA with backbone composed of glycerol-phosphate repeating units only substituted with d-alanine (Ala) and the lipid anchor, typically for genus Staphyloccocus, possessing the structure β-d-Glcp(1→6)- β-d-Glcp(1→3)-1,2-diacyl-sn-Gro.
authors.affiliation: Junior Research Group Allergobiochemistry. Electronic address: kduda@fz-borstel.de.
authors.forename: Katarzyna A
authors.initials: KA
authors.lastname: Duda
authors.affiliation: Division of Structural Biochemistry, Priority Area Asthma and Allergies, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Parkallee 4a/c, D-23845 Borstel, Germany.
authors.forename: Sandra
authors.initials: S
authors.lastname: Petersen
authors.affiliation: Division of Structural Biochemistry, Priority Area Asthma and Allergies, Research Center Borstel, Leibniz-Center for Medicine and Biosciences, Airway Research Center North (ARCN), Member of the German Center for Lung Research (DZL), Parkallee 4a/c, D-23845 Borstel, Germany.
authors.forename: Otto
authors.initials: O
authors.lastname: Holst
mesh_terms: D002240:Carbohydrate Sequence; D008070:Lipopolysaccharides / Q000737:chemistry*; D013210:Staphylococcus / Q000737:chemistry*; D013682:Teichoic Acids / Q000737:chemistry*
chemical_list: D008070:Lipopolysaccharides; D013682:Teichoic Acids; C009900:lipoteichoic acid
keywords: Allergy-protection; LTA structure; NMR analysis; Staphylococcus sciuri