title: Ferrocene-functionalized graphene electrode for biosensing applications.
abstract: A novel ferrocene-functionalized reduced graphene oxide (rGO)-based electrode is proposed. It was fabricated by the drop casting of ferrocene-functionalized graphene onto polyester substrate as the working electrode integrated within screen-printed reference and counter electrodes. The ferrocene-functionalized rGO has been fully characterized using FTIR, XPS, contact angle measurements, SEM and TEM microscopy, and cyclic voltammetry. The XPS and EDX analysis showed the presence of Fe element related to the introduced ferrocene groups, which is confirmed by a clear CV signal at ca. 0.25 V vs. Ag/AgCl (0.1 KCl). Mediated redox catalysis of H2O2 and bio-functionalization with glucose oxidase for glucose detection were achieved by the bioelectrode providing a proof for potential biosensing applications.
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193 Barcelona, Spain; Université de Tunis El-Manar, Faculté des Sciences de Tunis, Laboratoire de Chimie Analytique et Electrochimie (LR99ES15), Campus universitaire de Tunis El-Manar, 2092, Tunis, Tunisia.
authors.forename: Amal
authors.initials: A
authors.lastname: Rabti
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193 Barcelona, Spain.
authors.forename: Carmen C
authors.initials: CC
authors.lastname: Mayorga-Martinez
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193 Barcelona, Spain.
authors.forename: Luis
authors.initials: L
authors.lastname: Baptista-Pires
authors.affiliation: Université de Tunis El-Manar, Faculté des Sciences de Tunis, Laboratoire de Chimie Analytique et Electrochimie (LR99ES15), Campus universitaire de Tunis El-Manar, 2092, Tunis, Tunisia. Electronic address: n.raouafi@fst.rnu.tn.
authors.forename: Noureddine
authors.initials: N
authors.lastname: Raouafi
authors.affiliation: Catalan Institute of Nanoscience and Nanotechnology (ICN2), CSIC and The Barcelona Institute of Science and Technology, Campus UAB, Bellaterra, 08193 Barcelona, Spain; ICREA, Barcelona, Catalonia, Spain. Electronic address: arben.merkoci@icn2.cat.
authors.forename: Arben
authors.initials: A
authors.lastname: Merkoçi
mesh_terms: D015374:Biosensing Techniques; D004566:Electrodes; D005296:Ferrous Compounds / Q000737:chemistry*; D005947:Glucose / Q000032:analysis; D006108:Graphite / Q000737:chemistry*; D057230:Limit of Detection; D000075163:Metallocenes / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D056951:Photoelectron Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D005296:Ferrous Compounds; D000075163:Metallocenes; D006108:Graphite; D005947:Glucose; C004998:ferrocene
keywords: Biosensor; Ferrocene; Functionalization; Non-enzymatic sensor; Reduced graphene oxide electrode