title: Rhodium(I)-Catalyzed Benzannulation of Heteroaryl Propargylic Esters: Synthesis of Indoles and Related Heterocycles.
abstract: A de novo synthesis of a benzene ring allows for the preparation of a diverse range of heterocycles including indoles, benzofurans, benzothiophenes, carbazoles, and dibenzofurans from simple heteroaryl propargylic esters using a unified carbonylative benzannulation strategy. Multiple substituents can be easily introduced to the C4-C7 positions of indoles and related heterocycles.
authors.affiliation: School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA.
authors.forename: Xiaoxun
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA.
authors.forename: Haibo
authors.initials: H
authors.lastname: Xie
authors.affiliation: Department of Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Nankai University, Tianjin, 300071, P. R. China.
authors.forename: Xiaoning
authors.initials: X
authors.lastname: Fu
authors.affiliation: School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA.
authors.forename: Ji-Tian
authors.initials: JT
authors.lastname: Liu
authors.affiliation: School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA.
authors.forename: Hao-Yuan
authors.initials: HY
authors.lastname: Wang
authors.affiliation: Guangdong Provincial Key Laboratory of New Drug Screening, School of Pharmaceutical Science, Southern Medical University, Gaungzhou, Guangdong, 510515, P. R. China. xbm08@aliyun.com.
authors.forename: Bao-Min
authors.initials: BM
authors.lastname: Xi
authors.affiliation: Department of Chemistry, University of Pittsburgh, Pittsburgh, PA, 15260, USA. pengliu@pitt.edu.
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.affiliation: Department of Chemistry, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Nankai University, Tianjin, 300071, P. R. China. xxfang@nankai.edu.cn.
authors.forename: Xiufang
authors.initials: X
authors.lastname: Xu
authors.affiliation: School of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA. weiping.tang@wisc.edu.|Department of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA. weiping.tang@wisc.edu.
authors.forename: Weiping
authors.identifier: http://orcid.org/0000-0002-0039-3196
authors.initials: W
authors.lastname: Tang
keywords: annulation; carbonylation; catalysis; indoles; rhodium