title: 23-Valent Pneumococcal Polysaccharide Vaccine Uptake in the United States Air Force HIV Program.
abstract: Streptococcus pneumoniae infection is a predominant cause of bacterial infection in HIV-infected individuals. However, reported rates of pneumococcal vaccination with 23-valent polysaccharide vaccine (PPV23) are variable. We evaluated uptake of PPV23 in patients diagnosed with HIV between 1996 and 2012 (n = 507) in the United States Air Force, a centralized HIV program with free access to care including vaccines and medications. A total of 411 (81.1%) patients received at least 1 PPV23 dose. The PPV23 vaccination within 1 year of diagnosis was greater for those diagnosed between 2004 and 2012 (n = 184, 86%) compared with 1996 to 2003 (n = 104, 56.5%; P < .001). For those with ≥6 years of follow-up, receipt of a second recommended PPV23 dose was greater for those diagnosed between 1996 and 2003 (n = 52, 57.8%) compared with 2004 to 2012 (n = 9, 28.1%; P = .004). Although first PPV23 vaccination was high in recent years, process improvement efforts are underway to overcome barriers and improve uptake of pneumococcal vaccines in our program.
authors.affiliation: Allergy/Immunology Service, Wilford Hall Ambulatory Surgical Center, Lackland Air Force Base, San Antonio, TX, USA.
authors.forename: Thad F
authors.initials: TF
authors.lastname: Ocampo
authors.affiliation: Joint Trauma System, United States Army Institute of Surgical Research, San Antonio Military Medical Center, Fort Sam Houston, San Antonio, TX, USA.
authors.forename: Tuan
authors.initials: T
authors.lastname: Le
authors.affiliation: Infectious Disease Service, Mike O'Callaghan Federal Hospital, Nellis AFB, NV, USA.
authors.forename: Peter E
authors.initials: PE
authors.lastname: Matthews
authors.affiliation: Infectious Disease Service, San Antonio Military Medical Center, Fort Sam Houston, San Antonio, TX, USA jason.f.okulicz.mil@mail.mil.
authors.forename: Jason F
authors.initials: JF
authors.lastname: Okulicz
mesh_terms: D000328:Adult; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D006801:Humans; D008297:Male; D008887:Military Medicine; D008889:Military Personnel / Q000706:statistics & numerical data*; D011008:Pneumococcal Infections / Q000517:prevention & control*; D022242:Pneumococcal Vaccines / Q000008:administration & dosage / Q000627:therapeutic use; D014481:United States; D014611:Vaccination / Q000706:statistics & numerical data*; D055815:Young Adult
chemical_list: C414006:23-valent pneumococcal capsular polysaccharide vaccine; D022242:Pneumococcal Vaccines
keywords: HIV; Streptococcus pneumoniae infection; pneumococcal polysaccharide vaccine