title: Immunomodulatory effect of macrolides: At what cost?
abstract: We present the case of a 60-year old female patient, with a 10 year history of non-CF bronchiectasis and use of macrolides as maintenance immunomodulatory treatment, who was diagnosed with macrolide-resistant Mycobacterium avium complex lung disease. Macrolides' immunomodulatory effect is appealing for non- CF bronchiectasis patients, hiding a high risk for resistance emergence.
authors.affiliation: Respiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece; Pulmonary Department, 424 General Military Hospital, Thessaloniki, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Kipourou
authors.affiliation: Respiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
authors.forename: Katerina
authors.initials: K
authors.lastname: Manika
authors.affiliation: Tuberculosis Department, 'Sotiria' Chest Diseases Hospital, Athens, Greece.
authors.forename: Apostolos
authors.initials: A
authors.lastname: Papavasileiou
authors.affiliation: Respiratory Failure Unit, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Georgia
authors.initials: G
authors.lastname: Pitsiou
authors.affiliation: Respiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
authors.forename: Martha
authors.initials: M
authors.lastname: Lada
authors.affiliation: Pulmonary Department, 424 General Military Hospital, Thessaloniki, Greece.
authors.forename: Evangelos
authors.initials: E
authors.lastname: Ntinapogias
authors.affiliation: Respiratory Infections Unit, Pulmonary Department, Aristotle University of Thessaloniki, G. Papanikolaou Hospital, Thessaloniki, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Kioumis
keywords: Bronchiectasis; Macrolides; Non-tuberculous mycobacteria