title: Investigation and treatment of ovine psoroptic otoacariasis.
abstract: BACKGROUND
  Psoroptic otoacariasis has been described worldwide and is caused by a mite morphologically indistinguishable from the sheep scab mite Psoroptes ovis. A single treatment of affected sheep with 200 μg/kg of injectable ivermectin is reported to be curative.
  
  
  METHODS
  Psoroptes mites were isolated following treatment with ivermectin, but treatment with moxidectin at 1 mg/kg caused complete cessation of clinical signs. Affected animals were seropositive to Pso o 2 antigen enzyme-linked immunosorbent assay (ELISA) and had serum haptoglobin concentrations that overlapped with those described for field infections of classical sheep scab.
  
  
  CONCLUSIONS
  Psoroptic otoacariasis is not controlled by single treatments of injectable ivermectin but resolves after a single treatment with injectable moxidectin. Pso o 2 ELISA can detect infection with Psoroptes spp. mites but cannot distinguish between sheep scab and psoroptic otoacariasis.
authors.affiliation: Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian, EH25 9RG, UK.
authors.forename: James Patrick
authors.initials: JP
authors.lastname: Crilly
authors.affiliation: Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, EH26 0PZ, UK.
authors.forename: Francesca
authors.initials: F
authors.lastname: Nunn
authors.affiliation: Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, EH26 0PZ, UK.
authors.forename: Valentina
authors.initials: V
authors.lastname: Busin
authors.affiliation: Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, EH26 0PZ, UK.
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Marr
authors.affiliation: Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian, EH25 9RG, UK.
authors.forename: Amy E
authors.initials: AE
authors.lastname: Jennings
authors.affiliation: Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Midlothian, EH26 0PZ, UK.
authors.forename: Stewart T G
authors.initials: ST
authors.lastname: Burgess
authors.affiliation: Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Roslin, Midlothian, EH25 9RG, UK.
authors.forename: Neil D
authors.initials: ND
authors.lastname: Sargison