title: Electron Microscopic Comparison of Radial Artery Grafts in Non-Diabetic and Diabetic Coronary Bypass Patients.
abstract: OBJECTIVE
  We compared electron microscopic histologic changes of the radial artery grafts in non-diabetic and diabetic patients.
  
  
  METHODS
  Thirty-six patients were divided into three groups according to their diabetic status (Group I had no diabetes mellitus [DM], Group II had type two DM and HbA1c levels were <7.5%, and Group III had type 2 DM but HbA1c levels were >7.5%). Distal parts of radial artery grafts were evaluated with scanning electron microscopy in a blind fashion by two histologists. Electron microscopic scores were compared among the groups.
  
  
  RESULTS
  Radial artery electron microscopic scores were significantly different between group 1, 2 and 1, 3 and 2, 3 (p = 0.028, p < 0.001, and p < 0.001). In linear regression analysis, duration of DM (p = 0.027) and fasting plasma glucose (p = 0.001) were found as independent risk factors for histologic changes of radial artery grafts.
  
  
  CONCLUSIONS
  Duration of DM and poor glycemic control were found to be associated with radial artery electron microscopic changes. doi: 10.1111/jocs.12761 (J Card Surg 2016;31:410-415).
authors.affiliation: Department of Cardiovascular Surgery, Acibadem International Hospital, Istanbul, Turkey.
authors.forename: Mete
authors.initials: M
authors.lastname: Gürsoy
authors.affiliation: Cerrahpasa Faculty of Medicine, Department of Histology and Embryology, Istanbul University, Istanbul, Turkey.
authors.forename: Elif
authors.initials: E
authors.lastname: Güzel
authors.affiliation: Cerrahpasa Faculty of Medicine, Department of Histology and Embryology, Istanbul University, Istanbul, Turkey.
authors.forename: Pelin
authors.initials: P
authors.lastname: Ertürküner
authors.affiliation: Division of Health Management, Vocational School of Health Services, Acibadem University, Istanbul, Turkey.
authors.forename: Idil
authors.initials: I
authors.lastname: Çakır
authors.affiliation: Department of Cardiology, Acibadem International Hospital, Istanbul, Turkey.
authors.forename: Egemen
authors.initials: E
authors.lastname: Duygu
authors.affiliation: Department of Anesthesiology, Acibadem International Hospital, Istanbul, Turkey.
authors.forename: Füsun
authors.initials: F
authors.lastname: Gülcan
authors.affiliation: Department of Cardiovascular Surgery, Acibadem International Hospital, Istanbul, Turkey.
authors.forename: A Faruk
authors.initials: AF
authors.lastname: Hökenek
mesh_terms: D000368:Aged; D001026:Coronary Artery Bypass; D003327:Coronary Disease / Q000150:complications* / Q000601:surgery*; D003924:Diabetes Mellitus, Type 2 / Q000150:complications* / Q000378:metabolism; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D016014:Linear Models; D064347:Microscopy, Electrochemical, Scanning; D008875:Middle Aged; D017534:Radial Artery / Q000637:transplantation* / Q000648:ultrastructure*
chemical_list: D006442:Glycated Hemoglobin; C517652:hemoglobin A1c protein, human