title: Mitochondrial Replacement Techniques: Divergence in Global Policy.
abstract: In 2015, the UK became the first country permitting the clinical application of mitochondrial replacement techniques (MRT). Here, we explore how MRT have led to diverging international policy. In response, we recommend focused regulatory efforts coupled with United Nations (UN) leadership to build international consensus on the future of MRT.
authors.affiliation: Global Health Policy Institute, 8950 Villa La Jolla Drive, A203, La Jolla, CA 92037, USA.
authors.forename: Johanna
authors.initials: J
authors.lastname: Schandera
authors.affiliation: Global Health Policy Institute, 8950 Villa La Jolla Drive, A203, La Jolla, CA 92037, USA. Electronic address: tmackey@ucsd.edu.
authors.forename: Tim K
authors.initials: TK
authors.lastname: Mackey
mesh_terms: D057890:Epigenomics; D005854:Germ Cells / Q000378:metabolism; D006801:Humans; D008928:Mitochondria / Q000235:genetics*; D028361:Mitochondrial Diseases / Q000235:genetics* / Q000628:therapy; D000069321:Mitochondrial Replacement Therapy / Q000639:trends*; D006113:United Kingdom; D014480:United Nations
keywords: epigenetics; germline modification; germline regulation; mitochondrial disease.; mitochondrial donation; mitochondrial replacement techniques