title: Effects of coating spherical iron oxide nanoparticles.
abstract: We investigate the effect of several coatings applied in biomedical applications to iron oxide nanoparticles on the size, structure and composition of the particles. The four structural techniques employed - TEM, DLS, VSM, SAXS and EXAFS - show no significant effects of the coatings on the spherical shape of the bare nanoparticles, the average sizes or the local order around the Fe atoms. The NPs coated with hydroxylmethylene bisphosphonate or catechol have a lower proportion of magnetite than the bare and citrated ones, raising the question whether the former are responsible for increasing the valence state of the oxide on the NP surfaces and lowering the overall proportion of magnetite in the particles. VSM measurements show that these two coatings lead to a slightly higher saturation magnetization than the citrate. This article is part of a Special Issue entitled "Science for Life" Guest Editor: Dr. Austen Angell, Dr. Salvatore Magazù and Dr. Federica Migliardo.
authors.affiliation: Powder Technology Laboratory, Ecole Polytechnique Federale de Lausanne (EPFL), CH-1015 Lausanne, Switzerland.
authors.forename: Irena
authors.initials: I
authors.lastname: Milosevic
authors.affiliation: Inserm, U1148, Laboratory for Vascular Translational Science, UFR SMBH, Université Paris 13, Sorbonne Paris Cité, F-93017 Bobigny, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Motte
authors.affiliation: Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
authors.forename: Bachir
authors.initials: B
authors.lastname: Aoun
authors.affiliation: Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.affiliation: Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
authors.forename: Yang
authors.initials: Y
authors.lastname: Ren
authors.affiliation: Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
authors.forename: Chengjun
authors.initials: C
authors.lastname: Sun
authors.affiliation: IMPMC, UPMC, UMR CNRS 7590, 4 Place Jussieu, F-75005 Paris, France; University of Orleans, Orleans, France; BCMaterials, Edificio No. 500, Parque Tecnológico de Vizcaya, 48160 Derio, Spain. Electronic address: ml.saboungi@gmail.com.
authors.forename: Marie-Louise
authors.initials: ML
authors.lastname: Saboungi
mesh_terms: D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D000067493:Dynamic Light Scattering; D005290:Ferric Compounds / Q000737:chemistry*; D057446:Hydrodynamics; D006863:Hydrogen-Ion Concentration; D060306:Magnetometry; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D010316:Particle Size; D053838:Scattering, Small Angle; D017550:Spectroscopy, Fourier Transform Infrared; D055672:Static Electricity; D056928:X-Ray Absorption Spectroscopy; D014961:X-Ray Diffraction
chemical_list: D020099:Coated Materials, Biocompatible; D005290:Ferric Compounds; C000499:ferric oxide
keywords: Coating; Magnetic nanoparticle; Synchrotron X-ray; Valence state