title: A case of simultaneous esophageal squamous cell carcinoma and Barrett's adenocarcinoma.
abstract: A 77-year-old male with a long history of alcohol consumption and smoking was admitted for hoarseness and dysphagia. Computed tomography revealed thickening of the middle intrathoracic esophageal wall and multiple mediastinal lymph node swellings. Esophagogastroduodenoscopic examination disclosed an advanced-stage squamous cell carcinoma lesion in the middle intrathoracic esophagus with synchronous early stage Barrett's adenocarcinoma. The patient underwent endoscopic submucosal dissection for the adenocarcinoma followed by chemoradiation therapy for the squamous cell carcinoma. In spite of their common risk factors, the simultaneous manifestation of esophageal squamous cell carcinoma and Barrett's adenocarcinoma is extremely rare and requires further study.
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.|Division of Gastroenterology and Hepatology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Tomoo
authors.initials: T
authors.lastname: Yamazaki
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan. yiwaya@shinshu-u.ac.jp.|Division of Gastroenterology and Hepatology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan. yiwaya@shinshu-u.ac.jp.
authors.forename: Yugo
authors.initials: Y
authors.lastname: Iwaya
authors.affiliation: Department of Pathology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Mai
authors.initials: M
authors.lastname: Iwaya
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Takayuki
authors.initials: T
authors.lastname: Watanabe
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Ayako
authors.initials: A
authors.lastname: Seki
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Yasuhide
authors.initials: Y
authors.lastname: Ochi
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Etsuo
authors.initials: E
authors.lastname: Hara
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Sekiguchi
authors.affiliation: Department of Pathology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Noriko
authors.initials: N
authors.lastname: Hosaka
authors.affiliation: Endoscopic Examination Center, Shinshu University Hospital, Matsumoto, Japan.
authors.forename: Norikazu
authors.initials: N
authors.lastname: Arakura
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, Shinshu University School of Medicine, Matsumoto, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Tanaka
authors.affiliation: Department of Gastroenterology, Nagano Municipal Hospital, Nagano, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Hasebe
mesh_terms: D000230:Adenocarcinoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D000368:Aged; D001471:Barrett Esophagus / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery; D001706:Biopsy; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D004938:Esophageal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery / Q000628:therapy; D000077277:Esophageal Squamous Cell Carcinoma; D004947:Esophagus / Q000473:pathology; D006801:Humans; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy; D000072078:Positron Emission Tomography Computed Tomography; D012307:Risk Factors
keywords: Barrett’s adenocarcinoma; Cancer risk; Esophageal squamous cell carcinoma