title: Rhabdomyolysis in hyponatremia and paraneoplastic syndrome of inappropriate antidiuresis.
abstract: We report a 26-year-old woman admitted to our hospital for generalized tonic seizure. Laboratory investigations revealed severe hyponatremia possibly triggered by vomiting and diarrhea. 24 hours after correction of hyponatremia she developed diffuse myalgias and marked hyperCKemia. Syndrome of inappropriate antidiuresis (SIAD) was suspected as cause of hyponatremia. Abnormal vaginal bleeding prompts gynecological evaluation and a small-cell carcinoma of uterine cervix was detected.
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Elisabetta
authors.initials: E
authors.lastname: D'Adda
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Rosina
authors.initials: R
authors.lastname: Paletta
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Brusaferri
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Antonio
authors.initials: A
authors.lastname: Cagnana
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Maria
authors.initials: M
authors.lastname: Teresa Ferrò
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Michele
authors.initials: M
authors.lastname: Gennuso
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Isabella
authors.initials: I
authors.lastname: Ghione
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Riccardo
authors.initials: R
authors.lastname: Saponara
authors.affiliation: Department of Neurology and Stroke Unit, Ospedale Maggiore Crema, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Prelle
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007010:Hyponatremia / Q000175:diagnosis* / Q000628:therapy; D007177:Inappropriate ADH Syndrome / Q000175:diagnosis* / Q000628:therapy; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D012206:Rhabdomyolysis / Q000175:diagnosis* / Q000628:therapy; D002583:Uterine Cervical Neoplasms / Q000175:diagnosis* / Q000628:therapy
keywords: hyponatriemia; rhabdomyolisis; small cell neuroendocrine carcinoma; syndrome of inappropriate antidiuresis