title: Are Patients with Polycystic Ovarian Syndrome Ideal Candidates for Oocyte Donation?
abstract: Background. The use of donated oocytes for in vitro fertilization treatment in patients with ovarian failure is universally recognized. But would patients with polycystic ovarian syndrome (PCOS) be a good choice for egg donation programs? Objective. Comparing the pregnancy rates of egg receptors from donor patients diagnosed with PCOS to receptors from donors without PCOS. Design. Retrospective cohort study. Methods. A total of 234 patients who had undergone egg reception program were separated into two groups: Group I, receptors from PCOS donors (n = 36); Group II, receptors from donors without PCOS (n = 198). Medical records were reviewed and the fertilization, implantation, and pregnancy rates were calculated. Results. PCOS patients had an average of 3.23 more oocytes retrieved, but there were no differences in the number of mature oocytes that were used for donation between the groups. We also observed that the number of transferred embryos was also not significantly different, as well as the fertilization and implantation rates. The clinical pregnancy rates were not significantly different: 28% and 26% in Group I and Group II, respectively. Conclusions. Women with PCOS should not be excluded from egg donation programs.
authors.affiliation: Department of Gynecology, Rio de Janeiro State University, 20551-030 Rio de Janeiro, RJ, Brazil; Vida Fertility Center, 22793-080 Rio de Janeiro, RJ, Brazil.
authors.forename: George Queiroz
authors.initials: GQ
authors.lastname: Vaz
authors.affiliation: Department of Gynecology, Rio de Janeiro State University, 20551-030 Rio de Janeiro, RJ, Brazil; Vida Fertility Center, 22793-080 Rio de Janeiro, RJ, Brazil.
authors.forename: Alessandra Viviane
authors.initials: AV
authors.lastname: Evangelista
authors.affiliation: Vida Fertility Center, 22793-080 Rio de Janeiro, RJ, Brazil.
authors.forename: Cassio Alessandro Paganoti
authors.initials: CA
authors.lastname: Sartorio
authors.affiliation: Vida Fertility Center, 22793-080 Rio de Janeiro, RJ, Brazil.
authors.forename: Maria Cecilia Almeida
authors.initials: MC
authors.lastname: Cardoso
authors.affiliation: Vida Fertility Center, 22793-080 Rio de Janeiro, RJ, Brazil.
authors.forename: Maria Cecilia
authors.initials: MC
authors.lastname: Erthal
authors.affiliation: Department of Gynecology, Rio de Janeiro State University, 20551-030 Rio de Janeiro, RJ, Brazil; Vida Fertility Center, 22793-080 Rio de Janeiro, RJ, Brazil.
authors.forename: Paulo
authors.initials: P
authors.lastname: Gallo
authors.affiliation: Department of Gynecology, Rio de Janeiro State University, 20551-030 Rio de Janeiro, RJ, Brazil.
authors.forename: Marco Aurelio Pinho
authors.initials: MA
authors.lastname: Oliveira
mesh_terms: D000293:Adolescent; D000328:Adult; D001938:Brazil / Q000453:epidemiology; D015331:Cohort Studies; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data; D006801:Humans; D007247:Infertility, Female / Q000453:epidemiology* / Q000628:therapy*; D008875:Middle Aged; D018587:Oocyte Donation / Q000706:statistics & numerical data*; D018579:Patient Selection; D011085:Polycystic Ovary Syndrome / Q000453:epidemiology* / Q000628:therapy*; D011247:Pregnancy; D018873:Pregnancy Rate; D015995:Prevalence; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult