title: Role of cis-Monounsaturated Fatty Acids in the Prevention of Coronary Heart Disease.
abstract: The effects of cis-monounsaturated fatty acids (cis-MUFAs) on the risk of coronary heart disease (CHD) and on CHD mortality are not clear. Also, dietary recommendations for cis-MUFA as derived by various organizations are not in agreement. Earlier studies have mainly focused on the effects of cis-MUFA on serum lipids and lipoproteins. More recent studies, however, have also addressed effects of cis-MUFA on other non-traditional CHD risk markers such as vascular function markers, postprandial vascular function, and energy intake and metabolism. Although well-designed randomized controlled trials with CHD events as endpoints are missing, several large prospective cohort studies have recently been published on the relationship between cis-MUFA and CHD risk. The aim of this paper is to review these new studies that have been published in the last 3 years on the effects of cis-MUFA on cardiovascular risk markers and CHD.
authors.affiliation: Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, Maastricht, 6200 MD, The Netherlands.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Joris
authors.affiliation: Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Center, PO Box 616, Maastricht, 6200 MD, The Netherlands. r.mensink@maastrichtuniversity.nl.
authors.forename: Ronald P
authors.initials: RP
authors.lastname: Mensink
mesh_terms: D000818:Animals; D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000517:prevention & control; D003327:Coronary Disease / Q000517:prevention & control*; D004032:Diet; D002149:Energy Intake; D005229:Fatty Acids, Monounsaturated / Q000008:administration & dosage*; D006801:Humans; D012307:Risk Factors
chemical_list: D015415:Biomarkers; D005229:Fatty Acids, Monounsaturated
keywords: Cardiovascular disease; Coronary heart disease; Monounsaturated fatty acids; Oleic acid; Risk markers