title: [Analysis of choline alfoscerate effectiveness in chronic ocular ischemic syndrome].
abstract: OBJECTIVE
  To investigate the effectiveness of choline alphoscerate in patients with chronic ocular ischemic syndrome (OIS) and coexisting cerebrovascular disease.
  
  
  METHODS
  We performed a comprehensive examination of 51 patients aged 46--72 years (57.8±6.82 years on average) and diagnosed with OIS. Patients were divided into two groups. In group 1 (main group, 26 patients) the standard therapy was supplemented with choline alphoscerate. Group 2 (controls, 25 patients) received the standard therapy only.
  
  
  RESULTS
  Clinical and functional examinations revealed a more rapid and stable improvement of visual acuity in the choline alphoscerate group.
  
  
  CONCLUSIONS
  Development and application of an adequate combination therapy for patients with ocular ischemic syndrome has yielded an increase in visual acuity, visual fields, and the mean light sensitivity of the retina as well as an improvement of ocular hemodynamics.
authors.affiliation: Tashkent Institute of Postgraduate Medical Education, Ministry of Health of the Republic of Uzbekistan, 51 Parkent St., Tashkent, Uzbekistan, 100009.
authors.forename: Kh М
authors.initials: KМ
authors.lastname: Kamilov
authors.affiliation: Tashkent Institute of Postgraduate Medical Education, Ministry of Health of the Republic of Uzbekistan, 51 Parkent St., Tashkent, Uzbekistan, 100009.
authors.forename: M S
authors.initials: MS
authors.lastname: Kasimova
authors.affiliation: Tashkent Institute of Postgraduate Medical Education, Ministry of Health of the Republic of Uzbekistan, 51 Parkent St., Tashkent, Uzbekistan, 100009.
authors.forename: D К
authors.initials: DК
authors.lastname: Makhkamova
mesh_terms: D000368:Aged; D002561:Cerebrovascular Disorders / Q000150:complications*; D002908:Chronic Disease; D003941:Diagnostic Techniques, Ophthalmological; D016903:Drug Monitoring; D005123:Eye / Q000098:blood supply / Q000187:drug effects; D005128:Eye Diseases / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000503:physiopathology; D005260:Female; D005997:Glycerylphosphorylcholine / Q000008:administration & dosage*; D006801:Humans; D007511:Ischemia / Q000188:drug therapy / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D018697:Nootropic Agents / Q000008:administration & dosage; D016896:Treatment Outcome
chemical_list: D018697:Nootropic Agents; D005997:Glycerylphosphorylcholine