title: Achieving high resolution and optimizing sensitivity in spatial frequency encoding NMR spectroscopy: from theory to practice.
abstract: A detailed analysis of NMR spectra acquired based on spatial frequency encoding is presented. A theoretical model to simulate gradient encoded pulses is developed in order to describe the spatial properties of the NMR signals that are locally created throughout the sample. The key features that affect the efficiency of the slice selection process during excitation as well as refocusing pulses are investigated on a model ABX spin system, both theoretically and experimentally. It is shown that the sensitivity and resolution of the pure shift and J-edited experiments based on a spatial frequency encoding can be optimized to a point where high-resolution techniques based on a spatial frequency encoding approach show optimal performance compared to other methods.
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Plainchont
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Daisy
authors.initials: D
authors.lastname: Pitoux
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Ghanem
authors.initials: G
authors.lastname: Hamdoun
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Ouvrard
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Denis
authors.initials: D
authors.lastname: Merlet
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Farjon
authors.affiliation: Equipe de RMN en milieu orienté, ICMMO, UMR 8182 (CNRS-UPS), Université Paris-Saclay, 91405 Orsay cedex, France. nicolas.giraud@u-psud.fr.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Giraud