title: Dietary patterns and colorectal cancer.
abstract: Dietary pattern and lifestyle have been reported to be important risk factors in the development of colorectal cancer (CRC). However, the mechanism of action of dietary factors in CRC disease is unclear. The aim of this study is the examination of several dietary choices and their potential association with the risk of developing CRC.
  
  
  
  Dietary data was collected from 220 subjects who were previously diagnosed with CRC, and 281 control subjects (matched by age, gender, occupation and marital status). The data was collected between January 2010 and December 2012, using interview-based questionnaires. Multivariate logistic regression was used to estimate the relationship between dietary choices and risk of developing colorectal cancer.
  
  
  
  Factor analysis revealed three major dietary patterns. The first pattern we identified as the "Healthy Pattern", the second was identified as "High Sugar/High Tea Pattern" and the third as "Western Pattern". In the Healthy Pattern group we found a 10.54% variation in food intake, while the intake variation was 11.64% in the Western Pattern. After adjusting for confounding factors, the Western Pattern food choice was found to be significantly associated with an increased risk of developing CRC (OR = 1.88; 95% CI = 1.12-3.16). The results for the Healthy and High-Sugar/High Tea Patterns showed a decrease, but the statistic was not significant for the risk of CRC development.
  
  
  
  The Western Pattern of dietary choice was directly associated with CRC. The association between the dietary food choice in the Healthy and High-Sugar/High Tea Patterns and colorectal cancer needs further study in our Jordanian population.
authors.affiliation: Department of Nutrition and Food Technology, Faculty of Agriculture, The University of Jordan, Amman 11942 Jordan. Electronic address: r.tayyem@ju.edu.jo.
authors.forename: Reema F
authors.initials: RF
authors.lastname: Tayyem
authors.affiliation: Human Nutrition Department, College of Health Sciences, Qatar University, P.O. Box: 2713, Doha, Qatar. Electronic address: hbawadi@qu.ed.qa.
authors.forename: Hiba A
authors.initials: HA
authors.lastname: Bawadi
authors.affiliation: Chief Gastroenterology Division, King Hussein Cancer Center, Jordan. Electronic address: ishehadeh@khcc.jo.
authors.forename: Ihab
authors.initials: I
authors.lastname: Shehadah
authors.affiliation: Department of Clinical Nutrition & Dietetic, The Hashemite University, P.O. Box 150459, Zarqa 13115, Jordan. Electronic address: elonafrsh2003@yahoo.com.
authors.forename: Lana M
authors.initials: LM
authors.lastname: Agraib
authors.affiliation: Department of Clinical Nutrition & Dietetic, The Hashemite University, P.O. Box 150459, Zarqa 13115, Jordan. Electronic address: suhad.abumweis@hu.edu.jo.
authors.forename: Suhad S
authors.initials: SS
authors.lastname: AbuMweis
authors.affiliation: Jordan University of Science and Technology, Jordan. Electronic address: tmrjaberi@hotmail.com.
authors.forename: Tareq
authors.initials: T
authors.lastname: Al-Jaberi
authors.affiliation: Chief Gastroenterology Division, Prince Hamza Hospital, Jordan.
authors.forename: Majed
authors.initials: M
authors.lastname: Al-Nusairr
authors.affiliation: Faculty of Medicine, Hashemite University, Jordan. Electronic address: k_banihani@hu.edu.jo.
authors.forename: Kamal E
authors.initials: KE
authors.lastname: Bani-Hani
authors.affiliation: Cancer Prevention and Control Program, Moores Cancer Center, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: dheath@ucsd.edu.
authors.forename: Dennis D
authors.initials: DD
authors.lastname: Heath
mesh_terms: D000328:Adult; D016022:Case-Control Studies; D002755:Choice Behavior; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000517:prevention & control*; D004032:Diet; D066273:Diet, Western / Q000009:adverse effects; D015444:Exercise; D005260:Female; D005518:Food Preferences; D015438:Health Behavior; D006801:Humans; D008019:Life Style; D008297:Male; D008875:Middle Aged; D015596:Nutrition Assessment; D025341:Principal Component Analysis; D012307:Risk Factors; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires
keywords: Colorectal cancer; Dietary pattern; Healthy dietary pattern; Western dietary pattern