title: A Comparison of the Effectiveness of Triamcinolone and Radiation Therapy for Ear Keloids after Surgical Excision: A Systematic Review and Meta-Analysis.
abstract: BACKGROUND
  The ear is a common site for keloid formation, usually after trauma or ear piercing. This study is a meta-analysis to identify effective treatments for ear keloids after surgical excision.
  
  
  METHODS
  A systematic literature review and meta-analysis were performed using core databases. Postoperative adjuvant treatment modalities for ear keloids and recurrence rates were extracted and analyzed. Fixed and random effect models were applied.
  
  
  RESULTS
  Twenty-five studies published before August of 2015 were identified. The recurrence rate after surgical excision of an ear keloid in the triamcinolone group was estimated as 15.4 percent (95 percent CI, 9.4 to 24.1 percent; p < 0.001). The recurrence rate in the radiation therapy group was estimated as 14.0 percent (95 percent CI, 9.6 to 19.9 percent; p < 0.001).
  
  
  CONCLUSIONS
  Although a large-scale, randomized study is required for confirmation, both triamcinolone and radiation therapy provided outstanding treatment for ear keloids after surgical excision without a significant difference between the two treatments.
authors.affiliation: Jeonju, Republic of Korea.|From the Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Shin
authors.affiliation: Jeonju, Republic of Korea.|From the Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University.
authors.forename: Jin-Won
authors.initials: JW
authors.lastname: Lee
authors.affiliation: Jeonju, Republic of Korea.|From the Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University.
authors.forename: Si-Gyun
authors.initials: SG
authors.lastname: Roh
authors.affiliation: Jeonju, Republic of Korea.|From the Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University.
authors.forename: Nae-Ho
authors.initials: NH
authors.lastname: Lee
authors.affiliation: Jeonju, Republic of Korea.|From the Department of Plastic and Reconstructive Surgery, Medical School of Chonbuk National University.
authors.forename: Kyung-Moo
authors.initials: KM
authors.lastname: Yang
mesh_terms: D004431:Ear, External / Q000601:surgery*; D005938:Glucocorticoids / Q000008:administration & dosage; D006801:Humans; D007627:Keloid / Q000188:drug therapy* / Q000532:radiotherapy*; D014221:Triamcinolone / Q000008:administration & dosage*
chemical_list: D005938:Glucocorticoids; D014221:Triamcinolone