title: Dataset of mitochondrial genome variants associated with asymptomatic atherosclerosis.
abstract: This dataset report is dedicated to mitochondrial genome variants associated with asymptomatic atherosclerosis. These data were obtained using the method of next generation pyrosequencing (NGPS). The whole mitochondrial genome of the sample of patients from the Moscow region was analyzed. In this article the dataset including anthropometric, biochemical and clinical parameters along with detected mtDNA variants in patients with carotid atherosclerosis and healthy individuals was presented. Among 58 of the most common homoplasmic mtDNA variants found in the observed sample, 7 variants occurred more often in patients with atherosclerosis and 16 variants occurred more often in healthy individuals.
authors.affiliation: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Margarita A
authors.initials: MA
authors.lastname: Sazonova
authors.affiliation: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Andrey V
authors.initials: AV
authors.lastname: Zhelankin
authors.affiliation: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Valeria A
authors.initials: VA
authors.lastname: Barinova
authors.affiliation: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Vasily V
authors.initials: VV
authors.lastname: Sinyov
authors.affiliation: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Zukhra B
authors.initials: ZB
authors.lastname: Khasanova
authors.affiliation: Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Anton Y
authors.initials: AY
authors.lastname: Postnov
authors.affiliation: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Laboratory of Medical Genetics, Russian Cardiology Research and Production Complex, Moscow, Russian Federation.
authors.forename: Igor A
authors.initials: IA
authors.lastname: Sobenin
authors.affiliation: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Faculty of Medicine, School of Medical Sciences, University of New South Wales, Sydney, Australia.
authors.forename: Yuri V
authors.initials: YV
authors.lastname: Bobryshev
authors.affiliation: Institute of General Pathology and Pathophysiology Russian Academy of Medical Sciences, Moscow, Russian Federation; Institute for Atherosclerosis Research, Skolkovo Innovative Centre, Moscow Region, Russian Federation; Department of Biophysics, Biological Faculty, Moscow State University, Moscow, Russian Federation.
authors.forename: Alexander N
authors.initials: AN
authors.lastname: Orekhov
keywords: Asymptomatic atherosclerosis; Homoplasmic; Mitochondrial genome; mtDNA variant