title: Evaluation of Vacuum Assisted Closure Therapy for Soft Tissue Injury in Open Musculoskeletal Trauma.
abstract: BACKGROUND
  The application of controlled levels of negative or sub atmospheric pressure for a prolonged period of time on a wound had shown to accelerate removal of excess fluid and promote hyperaemia, which eventually promote wound healing.
  
  
  OBJECTIVE
  The study was conducted with the aim to evaluate the effectiveness of Vacuum Assisted Closure (VAC) therapy for soft tissue injury in open musculoskeletal trauma.
  
  
  METHODS
  Twenty cases of complex musculoskeletal wound involving different parts of body were included in this progressive randomized study. In patients, aggressive debridement was done before the application of VAC therapy. Controlled negative pressure was uniformly applied to the wound. Dressings were changed after every 4 to 5 days. The evaluation of results included healing rate of the wound, eradication of infection, complication rate, and number of secondary procedures.
  
  
  RESULTS
  VAC therapy over the wound was administered for an average of 20.4 days ±6.72 days (range 14 to 42 days). There was decrease in wound size attained by VAC therapy ranged from 2.6 to 24.4cm(2), with an average reduction of 10.55 cm(2). Three wounds were infected at the start of VAC therapy. However, all patients were cleared of bacterial infection by the end of VAC therapy.
  
  
  CONCLUSIONS
  VAC therapy using negative pressure promote Wound healing by increasing local capillary perfusion and increased rate of granulation tissue formation, decreases the duration of wound healing and requires fewer painful dressing change.
authors.affiliation: Lecturer, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: Manish
authors.initials: M
authors.lastname: Raj
authors.affiliation: Associate Professor, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: S P S
authors.initials: SP
authors.lastname: Gill
authors.affiliation: Associate Professor, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: Sunil Kumar
authors.initials: SK
authors.lastname: Sheopaltan
authors.affiliation: Assistant Professor, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: Pulkesh
authors.initials: P
authors.lastname: Singh
authors.affiliation: Assistant Professor, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.lastname: Dinesh
authors.affiliation: Assistant Professor, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: Jasveer
authors.initials: J
authors.lastname: Sigh
authors.affiliation: Junior Resident, Department of Orthopaedics, Uttar Pradesh Rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: Prateek
authors.initials: P
authors.lastname: Rastogi
authors.affiliation: Junior Resident, Department of Orthopaedics, UPRIMSR (Uttar Pradesh rural Institute of Medical Sciences and Research , Saifai, Etawah, U.P, India .
authors.forename: L N
authors.initials: LN
authors.lastname: Mishra
keywords: Negative Pressure; VAC; Wound Healing