title: Role of inflammation in developmental odontogenic pathosis.
abstract: Periapical infection in the primary tooth may lead to periapical abscess, granuloma, radicular cyst and even osteomyelitis. The infection in primary teeth can also affect the developing successor teeth leading to hypomineralization, hypoplasia, arrest of tooth development, regional odontodysplasia, delayed eruption etc. The purpose of this article is to report a case of malformed permanent tooth in relation to overlying infected deciduous teeth. The probable role of inflammation in pathogenesis of the present condition is also being discussed.
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, RKDF Dental College, Bhopal, Madhya Pradesh, India.
authors.forename: Sandeep S
authors.initials: SS
authors.lastname: Gupta
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, ITS College of Dental Studies and Research, Ghaziabad, Uttar Pradesh, India.
authors.forename: Devi C
authors.initials: DC
authors.lastname: Shetty
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, Maulana Azad Dental College, New Delhi, India.
authors.forename: Aadithya B
authors.initials: AB
authors.lastname: Urs
authors.affiliation: Department of Oral and Maxillofacial Pathology and Microbiology, RKDF Dental College, Bhopal, Madhya Pradesh, India.
authors.forename: P
authors.initials: P
authors.lastname: Nainani
keywords: Deciduous teeth; inflammation; malformed teeth; matrix metaloproteinases; radicular cyst