title: Dosimetry of indigenously developed (192)Ir high-dose rate brachytherapy source: An EGSnrc Monte Carlo study.
abstract: Clinical application using high-dose rate (HDR) (192)Ir sources in remote afterloading technique is a well-established treatment method. In this direction, Board of Radiation and Isotope Technology (BRIT) and Bhabha Atomic Research Centre, India, jointly indigenously developed a remote afterloading machine and (192)Ir HDR source. The two-dimensional (2D) dose distribution and dosimetric parameters of the BRIT (192)Ir HDR source are generated using EGSnrc Monte Carlo code system in a 40 cm dia × 40 cm height cylindrical water phantom. The values of air-kerma strength and dose rate constant for BRIT (192)Ir HDR source are 9.894 × 10(-8) ± 0.06% UBq(-1) and 1.112 ± 0.11% cGyh(-1)U(-1), respectively. The values of radial dose function (gL(r)) of this source compare well with the corresponding values of BEBIG, Flexisource, and GammaMed 12i source models. This is because of identical active lengths of the sources (3.5 mm) and the comparable phantom dimensions. A comparison of gL(r) values of BRIT source with microSelectron-v1 show differences about 2% at r = 6 cm and up to 13% at r = 12 cm, which is due to differences in phantom dimensions involved in the calculations. The anisotropy function of BRIT (192)Ir HDR source is comparable with the corresponding values of microSelectron-v1 (classic) HDR source.
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Navi Mumbai, Maharashtra, India.
authors.forename: Sridhar
authors.initials: S
authors.lastname: Sahoo
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Navi Mumbai, Maharashtra, India.
authors.forename: T Palani
authors.initials: TP
authors.lastname: Selvam
authors.affiliation: Radiological Physics and Advisory Division, Bhabha Atomic Research Centre, Navi Mumbai, Maharashtra, India.
authors.forename: S D
authors.initials: SD
authors.lastname: Sharma
authors.affiliation: Board of Radiation Isotope and Technology, Vashi, Navi Mumbai, Maharashtra, India.
authors.forename: Trupti
authors.initials: T
authors.lastname: Das
authors.affiliation: Board of Radiation Isotope and Technology, Vashi, Navi Mumbai, Maharashtra, India.
authors.forename: A C
authors.initials: AC
authors.lastname: Dey
authors.affiliation: Board of Radiation Isotope and Technology, Vashi, Navi Mumbai, Maharashtra, India.
authors.forename: B N
authors.initials: BN
authors.lastname: Patil
authors.affiliation: Board of Radiation Isotope and Technology, Vashi, Navi Mumbai, Maharashtra, India.
authors.forename: K V S
authors.initials: KV
authors.lastname: Sastri
keywords: 192Ir high-dose rate source; Brachytherapy; EGSnrc Monte Carlo; TG43