title: Molecularly imprinted nanohybrids based on dopamine-modified poly(γ-glutamic acid) for electrochemical sensing of melamine.
abstract: A voltammetric sensor for melamine (MEL) was prepared from molecularly imprinted nanohybrids (MINBs). A dopamine modified poly-γ-glutamic acid copolymer (γ-PGA-DA) and MEL were self-assembled into MEL/γ-PGA-DA nanoparticles (NPs) in aqueous solution via weak interactions, followed by adding an aqueous AgNO3 solution into the mixture. The Ag(+) was adsorbed in the MEL/γ-PGA-DA NPs and spontaneously reduced to Ag NPs by the dopamine moieties of γ-PGA-DA, forming Ag/MEL/γ-PGA-DA MINBs, which were then cast on a gold electrode to form a MINBs film. The MEL was removed by electrolysis via catalysis of Ag NPs at a constant potential of 1.4V in phosphate buffer saline solution, to obtain a voltammetric sensor for MEL. The sensor responded linearly to MEL in the concentration range of 5×10(-18) to 5×10(-7)molL(-1). Compared to other published molecularly imprinted polymer sensors for sensing MEL, the prepared MINBs sensor had much wider detection range with lower detection limit.
authors.affiliation: Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China; School of Biochemical Engineering, Anhui Polytechnic University, Wuhu 241000, China.
authors.forename: Rongli
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Sheng
authors.initials: S
authors.lastname: Xu
authors.affiliation: Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China. Electronic address: zhuye@jiangnan.edu.cn.
authors.forename: Ye
authors.initials: Y
authors.lastname: Zhu
authors.affiliation: Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Luo
authors.affiliation: Key Laboratory of Food Colloids and Biotechnology, Ministry of Education, School of Chemical and Material Engineering, Jiangnan University, Wuxi 214122, China.
authors.forename: Xiaoya
authors.initials: X
authors.lastname: Liu
authors.affiliation: School of Biochemical Engineering, Anhui Polytechnic University, Wuhu 241000, China. Electronic address: tangdx@ahpu.edu.cn.
authors.forename: Dingxing
authors.initials: D
authors.lastname: Tang
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D004298:Dopamine / Q000031:analogs & derivatives*; D055664:Electrochemical Techniques / Q000379:methods; D005504:Food Analysis / Q000379:methods; D057230:Limit of Detection; D008892:Milk / Q000737:chemistry*; D054802:Molecular Imprinting; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D011099:Polyglutamic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D012834:Silver / Q000737:chemistry; D014227:Triazines / Q000032:analysis*
chemical_list: D014227:Triazines; C511775:poly(gamma-glutamic acid); D011099:Polyglutamic Acid; D012834:Silver; C011907:melamine; D004298:Dopamine
keywords: Ag nanoparticles; Melamine sensor; Molecularly imprinted nanohybrids; Poly(γ-glutamic acid) nanoparticles