title: Immunohistochemical localization of irisin in skin, eye, and thyroid and pineal glands of the crested porcupine (Hystrix cristata).
abstract: Irisin was first identified in muscle cells. We detected irisin immunoreactivity in various organs of the crested porcupine (Hystrix cristata). In the epidermis, irisin immunoreactivity was localized mainly in stratum basale, stratum spinosum and stratum granulosum layers; immunoreactivity was not observed in the stratum corneum. In the dermis, irisin was found in the external and internal root sheath, cortex and medulla of hair follicles, and in sebaceous glands. Irisin immunoreactivity was found in the neural retina and skeletal muscle fibers associated with the eye. The pineal and thyroid glands also exhibited irisin immunoreactivity.
authors.affiliation: a Department of Histology-Embryology , Faculty of Veterinary Medicine, Firat University , Elazıg , Turkey.
authors.forename: B
authors.initials: B
authors.lastname: Gençer Tarakçı
authors.affiliation: a Department of Histology-Embryology , Faculty of Veterinary Medicine, Firat University , Elazıg , Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Girgin
authors.affiliation: a Department of Histology-Embryology , Faculty of Veterinary Medicine, Firat University , Elazıg , Turkey.
authors.forename: S
authors.initials: S
authors.lastname: Timurkaan
authors.affiliation: a Department of Histology-Embryology , Faculty of Veterinary Medicine, Firat University , Elazıg , Turkey.
authors.forename: M H
authors.initials: MH
authors.lastname: Yalçın
authors.affiliation: b Sabiha Gökcen Airport Veterinary Border Inspection Post , Ministry of Food, Agriculture and Livestock, Istanbul , Turkey.
authors.forename: F M
authors.initials: FM
authors.lastname: Gür
authors.affiliation: c Department of Anatomy , Faculty of Veterinary Medicine, Firat University , Elazig , Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Karan
mesh_terms: D000818:Animals; D005123:Eye / Q000378:metabolism*; D005260:Female; D005353:Fibronectins / Q000378:metabolism*; D007150:Immunohistochemistry; D008297:Male; D010870:Pineal Gland / Q000378:metabolism*; D046328:Porcupines; D012867:Skin / Q000378:metabolism*; D013961:Thyroid Gland / Q000378:metabolism*
chemical_list: D005353:Fibronectins
keywords: crested; eye; immunohistochemistry; irisin; pineal; porcupine; skin; thyroid