title: Nickel-Catalyzed Arylation of Heteroaryl-containing Diarylmethanes: Exceptional Reactivity of the Ni(NIXANTPHOS)-based Catalyst.
abstract: Nickel(0)-catalyzed cross-coupling of heteroaryl-containing diarylmethanes with both aryl bromides and chlorides has been achieved. The success of this reaction relies on the introduction of a unique nickel/NIXANTPHOS-based catalyst system, which provides a direct route to triarylmethanes from heteroaryl-containing diarylmethanes. Reactivity studies indicate the Ni(NIXANTPHOS)-based catalyst exhibits enhanced reactivity over XANTPHOS derivatives and other Ni(phosphine)-based catalysts in the reactions examined.
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, Beijing 100081, PR China; Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
authors.forename: Xinyu
authors.initials: X
authors.lastname: Cao
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
authors.forename: Sheng-Chun
authors.initials: SC
authors.lastname: Sha
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
authors.forename: Minyan
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
authors.forename: Byeong-Seon
authors.initials: BS
authors.lastname: Kim
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
authors.forename: Catherine
authors.initials: C
authors.lastname: Morgan
authors.affiliation: Key Laboratory of Cluster Science of Ministry of Education, School of Chemistry, Beijing Institute of Technology, Beijing 100081, PR China.
authors.forename: Rudan
authors.initials: R
authors.lastname: Huang
authors.affiliation: Key Laboratory of Medicinal Chemistry for Natural Resource, School of Chemical Science and Technology, Yunnan University, Kunming, 650091, PR China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Yang
authors.affiliation: Department of Chemistry, University of Pennsylvania, 231 S. 34th St., Philadelphia, PA 19104, USA.
authors.forename: Patrick J
authors.initials: PJ
authors.lastname: Walsh