title: [Investigation of the medical and social situation of patients managed by opiate replacement regimens for over 10 years by their GP].
abstract: OBJECTIVE
  Management with opiate replacement regimens (ORRs) of patients presenting to primary care settings with opiate addiction has become a long-term follow-up. The aim of this survey study was to describe patients who had been prescribed ORRs for at least 10 years by their general practitioner (GP).
  
  
  METHODS
  In 2011, two questionnaires were sent to a sample of 38 GPs prescribing ORRs in Northern France. Doctors' questionnaires collected their typology and opinions on their patients receiving opiate substitution treatments for over 10 years. Patients' questionnaires were completed in the presence of the patient.
  
  
  RESULTS
  Twenty-three doctors' and 83 patients' questionnaires were suitable for analysis. The average number of listed ORR patients was 14.2 and 3.6 had been managed for 10 years or more. Misuse persisted: 30.5% of GPs considered that it was carried out by at least by 15% of patients. Average dosages were 60.3 mg for methadone and 7.0 mg for buprenorphine. Employment (46.3% of patients had a salary), dwelling and family live (46.3% of patients were in charge of children) were favored. Nevertheless, precariousness persisted: 32% of patients were indebted and help of social workers was not systematically searched. One third of the patients were alcohol and cannabis misusers, 70% were smoking and 34.5% multiple drug misusers. An important number of patients were taking anxiolytics (37.8%) and hypnotics (30.5%).
  
  
  CONCLUSIONS
  After 10 years of follow-up for an ORR by a GP, the social situation of patients seems to have stabilized, but psychoactive drugs consumption remains important.
authors.affiliation: Faculté de Médecine Henri Warembourg F, 59045 Lille cedex, France. Electronic address: nassirme@hotmail.com.
authors.forename: Nassir
authors.initials: N
authors.lastname: Messaadi
authors.affiliation: Faculté de Médecine Henri Warembourg F, 59045 Lille cedex, France.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Favre
authors.affiliation: Service d'addictologie, CHRU de Lille, 59000 Lille, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Rolland
authors.affiliation: Service d'addictologie, CHRU de Lille, 59000 Lille, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Cottencin
authors.affiliation: Faculté de Médecine Henri Warembourg F, 59045 Lille cedex, France.
authors.forename: Matthieu
authors.initials: M
authors.lastname: Calafiore
authors.affiliation: Faculté de Médecine Henri Warembourg F, 59045 Lille cedex, France.
authors.forename: Bertrand
authors.initials: B
authors.lastname: Stalnikiewicz
authors.affiliation: Faculté de Médecine Henri Warembourg F, 59045 Lille cedex, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Berkhout
mesh_terms: D000328:Adult; D000701:Analgesics, Opioid / Q000008:administration & dosage; D002047:Buprenorphine / Q000008:administration & dosage; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D058005:General Practitioners; D006801:Humans; D008297:Male; D008691:Methadone / Q000008:administration & dosage; D008875:Middle Aged; D058850:Opiate Substitution Treatment; D009293:Opioid-Related Disorders / Q000534:rehabilitation*; D019966:Substance-Related Disorders / Q000453:epidemiology; D011795:Surveys and Questionnaires; D014478:Unemployment / Q000706:statistics & numerical data
chemical_list: D000701:Analgesics, Opioid; D002047:Buprenorphine; D008691:Methadone
keywords: Buprenorphine; Buprénorphine; General practice; Methadone; Médecine générale; Méthadone; Opiate substitution treatment; Traitement de substitution aux opiacés