title: First report of macroscopic biofilm formation caused by Candida albicans on silver hydrogel-coated urinary catheters.
abstract: We report macroscopic biofilms on silver hydrogel-coated urinary catheters in 2 patients from 2 different intensive care units. The catheters were removed on observation of a white, jelly layer on the catheters, respectively, 9 and 21 days after insertion. Yeast cells and pseudohyphal structures were observed with microscopy. Both isolates were identified as Candida albicans. To our knowledge, these are the first cases demonstrating the formation of macroscopic biofilm layers on silver nitrate-coated catheters in the literature.
authors.affiliation: Department of Medical Microbiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey. Electronic address: mbselek@gata.edu.tr.
authors.forename: Mehmet Burak
authors.initials: MB
authors.lastname: Selek
authors.affiliation: Department of Medical Microbiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
authors.forename: Tuğba
authors.initials: T
authors.lastname: Kula Atik
authors.affiliation: Department of Medical Microbiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
authors.forename: Bayhan
authors.initials: B
authors.lastname: Bektöre
authors.affiliation: Department of Anesthesiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
authors.forename: Bülent
authors.initials: B
authors.lastname: Atik
authors.affiliation: Department of Neurology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Demir
authors.affiliation: Department of Medical Microbiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Baylan
authors.affiliation: Department of Medical Microbiology, Haydarpaşa Training Hospital, Gülhane Military Medical Academy, İstanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Özyurt
mesh_terms: D018441:Biofilms / Q000254:growth & development*; D002176:Candida albicans / Q000187:drug effects* / Q000254:growth & development / Q000302:isolation & purification; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000494:pharmacology*; D007362:Intensive Care Units; D012834:Silver / Q000494:pharmacology; D062885:Urinary Catheters / Q000382:microbiology*; D014552:Urinary Tract Infections / Q000517:prevention & control*
chemical_list: D020136:Hydrogel, Polyethylene Glycol Dimethacrylate; D012834:Silver
keywords: Candida albicans; biofilm; urinary catheter