title: Economic impact of recurrent respiratory papillomas in a UK adult population.
abstract: OBJECTIVE
  To calculate the financial burden of recurrent respiratory papilloma. This study is UK-based, where up until now no financial estimates have been calculated for this group of patients.
  
  
  BACKGROUND
  Recurrent respiratory papilloma is caused by the human papilloma virus (subtypes 6 and 11). The burden for the patient and the healthcare system is significant given the recurrent nature of the disease.
  
  
  METHODS
  Data were collected, using a questionnaire completed during routine clinical follow up, from a single centre managing recurrent respiratory papilloma in Glasgow, Scotland. Cost information was sourced from the Scottish Government's Information Services Division.
  
  
  RESULTS
  Fourteen patients with active recurrent respiratory papilloma between 2013 and 2014 were identified. The direct measurable cost to NHS Greater Glasgow and Clyde amounted to £107 478.
  
  
  CONCLUSIONS
  Recurrent respiratory papilloma is a benign condition, but the financial implications of diagnosis are significant. Recurrent respiratory papilloma has a natural history of relapse and remission, and patients may require healthcare input over a period of several years.
authors.affiliation: Department of Otolaryngology,North Manchester General Hospital,Pennine Acute Trust,UK.
authors.forename: A
authors.initials: A
authors.lastname: Harrison
authors.affiliation: Department of Otolaryngology,Queen Elizabeth University Hospital,Glasgow,Scotland,UK.
authors.forename: J
authors.initials: J
authors.lastname: Montgomery
authors.affiliation: Department of Otolaryngology,Gartnavel General Hospital,Glasgow,Scotland,UK.
authors.forename: F B
authors.initials: FB
authors.lastname: Macgregor
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D005260:Female; D006296:Health Services / Q000706:statistics & numerical data*; D006801:Humans; D007828:Laryngoscopy / Q000191:economics*; D008297:Male; D008875:Middle Aged; D030361:Papillomavirus Infections / Q000191:economics* / Q000628:therapy; D012141:Respiratory Tract Infections / Q000191:economics* / Q000628:therapy; D012606:Scotland; D018582:Sick Leave / Q000191:economics*; D013070:Speech Therapy / Q000191:economics*; D013222:State Medicine; D006113:United Kingdom; D055815:Young Adult
keywords: 11; 16; 18; Cost Of Illness; Human Papillomavirus Recombinant Vaccine Quadrivalent; Papilloma; Recurrent Respiratory Papillomatosis; Types 6