title: [MIKAMINOM ANTIFUNGAL THERAPY IN NEWBORNS AND INFANTS WITH SURGICAL PATHOLOGY].
abstract: Prolonged empiric and etiotropic therapy of multidrug-resistant or pan-resistant bacterial flora in different gestation age newborns has led to the growth of resistant fungalflora in intencive care units (ICU). According to risk factors and rating scales every child of ICU undergoing the abdominal cavity surgery is threatened the development of a fungal infection and requires antifungal therapy appointment or causal prophylactic. In recent years, before the advent of medications of the group of echinocandins, therapy of invasive fungal infections has been a challenge. Currently alternative drug to diflucane in neonates and infants is micafungine (mycamine) in the dose of 2-8 mg/kg/day, depending on the signs of infestation and severity of the condition.
authors.forename: N I
authors.initials: NI
authors.lastname: Melnikova
authors.forename: I A
authors.initials: IA
authors.lastname: Strogonov
authors.forename: E V
authors.initials: EV
authors.lastname: Kartseva
authors.forename: G D
authors.initials: GD
authors.lastname: Haritonova
authors.forename: O E
authors.initials: OE
authors.lastname: Gliznutsin
authors.forename: S V
authors.initials: SV
authors.lastname: Gabulaev
authors.forename: E M
authors.initials: EM
authors.lastname: Pulikova
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy / Q000382:microbiology; D002175:Candida / Q000187:drug effects / Q000302:isolation & purification; D002177:Candidiasis / Q000382:microbiology / Q000401:mortality / Q000517:prevention & control*; D000013:Congenital Abnormalities / Q000401:mortality / Q000601:surgery*; D054714:Echinocandins / Q000008:administration & dosage / Q000627:therapeutic use*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D055666:Lipopeptides / Q000008:administration & dosage / Q000627:therapeutic use*; D000077551:Micafungin; D008826:Microbial Sensitivity Tests; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents; D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D000077551:Micafungin