title: [Whole-genome sequencing on one case of Han familial keloids].
abstract: OBJECTIVE
  To screen SNP information of keloid pedigrees through whole genome sequencing.
  
  
  METHODS
  We Collected information and clinical data of the keloid pedigree and constructed charts of the pedigree. The DNA was extracted from peripheral venous blood samples of the pedigree to sequence the whole genome.
  
  
  RESULTS
  27 SNP and 8 disease-associated genes were screened out.
  
  
  CONCLUSIONS
  Whole genome sequencing technology can select new genetic mutations associated with keloid, and provide a new way for the research of keloid.
authors.forename: Guodong
authors.initials: G
authors.lastname: Teng
authors.forename: Minliang
authors.initials: M
authors.lastname: Chen
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Liming
authors.initials: L
authors.lastname: Liang
mesh_terms: D002681:China / Q000208:ethnology; D015894:Genome, Human; D006801:Humans; D007627:Keloid / Q000235:genetics*; D009154:Mutation; D010375:Pedigree; D020641:Polymorphism, Single Nucleotide; D017422:Sequence Analysis, DNA