title: Mitochondria: Masters of Epigenetics.
abstract: Accumulating evidence argues that aging exerts a profound influence on epigenetics, and vice versa. A pair of studies by Merkwirth et al. and Tian et al. now provide insights on how mitochondrial stress experienced by C. elegans larvae propagates a specific and persistent epigenetic response that protects adult cells and extends lifespan.
authors.affiliation: Department of Ecology and Evolutionary Biology, Brown University, Providence, RI 02912, USA.
authors.forename: Marc
authors.initials: M
authors.lastname: Tatar
authors.affiliation: Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA. Electronic address: john_sedivy@brown.edu.
authors.forename: John M
authors.initials: JM
authors.lastname: Sedivy
mesh_terms: D000375:Aging; D000818:Animals; D017173:Caenorhabditis elegans / Q000378:metabolism*; D029742:Caenorhabditis elegans Proteins / Q000235:genetics*; D044127:Epigenesis, Genetic; D006801:Humans; D008136:Longevity; D008928:Mitochondria / Q000378:metabolism
chemical_list: D029742:Caenorhabditis elegans Proteins