title: Efficacy of a Single, Brief Alcohol Reduction Intervention among Men and Women Living with HIV/AIDS and Using Alcohol in Kampala, Uganda: A Randomized Trial.
abstract: We evaluated the efficacy of a brief motivational intervention (MI) counseling in reducing alcohol consumption among persons living with HIV/AIDS in Kampala, Uganda. Persons living with HIV/AIDS with Alcohol Use Disorders Identification Tool (AUDIT) score ≥3 points were randomized to either standardized positive prevention counseling alone or in combination with alcohol brief MI counseling. The mean change in AUDIT-C scores over 6 months was compared by treatment arm. The mean (standard deviation [SD]) AUDIT-C scores were 6.3 (2.3) and 6.8 (2.3) for control and MI arms ( P = .1) at baseline, respectively, and change in mean AUDIT-C score was not statistically different between arms over the 6 months ( P = .8). However, there was a statistically significant decrease in mean AUDIT-C score (-1.10; 95% confidence interval: -2.19 to -0.02, P = .046) among women in the MI arm. There was a nondifferential reduction in alcohol consumption overall, but MI appeared effective among women only. Studies with more than 1 counseling session and evaluation of gender differences in treatment response are needed.
authors.affiliation: 1 Department of epidemiology & Biostatistics, Makerere University School of Public Health, Kampala, Uganda.|4 Infectious Diseases Institute, Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
authors.forename: Bonnie
authors.initials: B
authors.lastname: Wandera
authors.affiliation: 1 Department of epidemiology & Biostatistics, Makerere University School of Public Health, Kampala, Uganda.
authors.forename: Nazarius Mbona
authors.initials: NM
authors.lastname: Tumwesigye
authors.affiliation: 2 Clinical Epidemiology Unit, Makerere University School of Medicine, Kampala, Uganda.
authors.forename: Joaniter Immaculate
authors.initials: JI
authors.lastname: Nankabirwa
authors.affiliation: 3 Department of Social work and Social administration, Makerere University College of Humanities and Social Sciences, Kampala, Uganda.
authors.forename: David Kaawa
authors.initials: DK
authors.lastname: Mafigiri
authors.affiliation: 4 Infectious Diseases Institute, Infectious Diseases Institute, College of Health Sciences, Makerere University, Kampala, Uganda.
authors.forename: Rosalind M
authors.initials: RM
authors.lastname: Parkes-Ratanshi
authors.affiliation: 5 Infectious Diseases Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom.
authors.forename: Saidi
authors.initials: S
authors.lastname: Kapiga
authors.affiliation: 6 Department of Medicine, University of California-San Francisco, San Francisco, CA, USA.
authors.forename: Judith
authors.initials: J
authors.lastname: Hahn
authors.affiliation: 7 Department of Population Health Sciences, University of Wiscsonsin School of Medicine and Public Health, Madison, WI, USA.
authors.forename: Ajay K
authors.initials: AK
authors.lastname: Sethi
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000503:physiopathology / Q000523:psychology; D000328:Adult; D000428:Alcohol Drinking / Q000523:psychology*; D003376:Counseling; D005260:Female; D015658:HIV Infections / Q000503:physiopathology / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D062405:Motivational Interviewing; D014454:Uganda
keywords: Africa; HIV/AIDS; alcohol; brief interventions; randomized trial