title: Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome.
abstract: Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting anti-viral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology.
authors.affiliation: Farhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
authors.forename: Farhad
authors.initials: F
authors.lastname: Sahebjam
authors.affiliation: Farhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
authors.forename: Cristina H
authors.initials: CH
authors.lastname: Hajdu
authors.affiliation: Farhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
authors.forename: Esther
authors.initials: E
authors.lastname: Nortey
authors.affiliation: Farhad Sahebjam, Esther Nortey, Samuel H Sigal, Division of Gastroenterology, New York University School of Medicine, New York, NY 10016, United States.
authors.forename: Samuel H
authors.initials: SH
authors.lastname: Sigal
keywords: Autoimmune hepatitis; Direct acting antiviral therapy; Hepatitis C; Overlap syndrome