title: [Efficacy of antiretroviral therapy and influencing factors for people living with HIV/AIDS in designated hospitals in Harbin].
abstract: OBJECTIVE
  To understand the efficacy of antiretroviral therapy for people living with HIV/AIDS and influencing factors; and provide evidence to improve the treatment of HIV infection and AIDS for the better life of the patients.
  
  
  METHODS
  A cross sectional study was conducted in designated AIDS hospitals in Harbin. A questionnaire was used to collect the information of the patients receiving treatment in these hospitals. The statistical analysis was done with software SAS 9.2 and Excel 2010. Univariate analysis was performed with t test and multivariate analysis was performed with ordinal logistic regression model. Wilcoxon ranks sum test was conducted to compare the CD4(+) T lymphocyte counts.
  
  
  RESULTS
  The number of the patients receiving antiretroviral therapy was in increase in recent years. The HIV infection route was mainly homosexual contact. The CD4(+)T lymphocyte count of the patients increased at different levels after ≥6 months treatment(P<0.01). Household income(P<0.05), adherence to treatment plan or not(P<0.05), social relationship(P< 0.05), concern of economic cost(P<0.01)medication compliance(P<0.01)and initial level of CD4(+) T lymphocyte(P<0.01)were the influencing factors for antiretroviral therapy efficacy.
  
  
  CONCLUSIONS
  In designated hospitals in Harbin, the number of the patients receiving HIV antiretroviral therapy kept to increase and the efficacy of the treatment was obvious.
authors.affiliation: Institution of Public Health, Harbin Medical University, Harbin 150081, China.
authors.forename: P Y
authors.initials: PY
authors.lastname: Zhao
authors.affiliation: Institution of Public Health, Harbin Medical University, Harbin 150081, China.
authors.forename: X
authors.initials: X
authors.lastname: Yu
authors.affiliation: Institution of Public Health, Harbin Medical University, Harbin 150081, China.
authors.forename: K
authors.initials: K
authors.lastname: Yang
authors.affiliation: Infection Department, Fourth Affiliated Hospital of Harbin Medical University, Harbin 150000, China.
authors.forename: S Y
authors.initials: SY
authors.lastname: Feng
authors.affiliation: Infection Department, Fourth Affiliated Hospital of Harbin Medical University, Harbin 150000, China.
authors.forename: F X
authors.initials: FX
authors.lastname: Wang
authors.affiliation: Institution of Public Health, Harbin Medical University, Harbin 150081, China.
authors.forename: B Y
authors.initials: BY
authors.lastname: Wang
mesh_terms: D000163:Acquired Immunodeficiency Syndrome; D023241:Antiretroviral Therapy, Highly Active / Q000379:methods*; D002681:China; D003141:Communicable Diseases; D003430:Cross-Sectional Studies; D015658:HIV Infections / Q000188:drug therapy* / Q000523:psychology / Q000821:virology; D006761:Hospitals; D006801:Humans; D011788:Quality of Life; D013601:T-Lymphocytes; D016896:Treatment Outcome; D016903:Drug Monitoring