title: Identification of CELF1 RNA targets by CLIP-seq in human HeLa cells.
abstract: The specific interactions between RNA-binding proteins and their target RNAs are an essential level to control gene expression. By combining ultra-violet cross-linking and immunoprecipitation (CLIP) and massive SoliD sequencing we identified the RNAs bound by the RNA-binding protein CELF1, in human HeLa cells. The CELF1 binding sites deduced from the sequence data allow characterizing specific features of CELF1-RNA association. We present therefore the first map of CELF1 binding sites in human cells.
authors.affiliation: Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Le Tonquèze
authors.affiliation: Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
authors.forename: Bernhard
authors.initials: B
authors.lastname: Gschloessl
authors.affiliation: Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
authors.forename: Vincent
authors.initials: V
authors.lastname: Legagneux
authors.affiliation: Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
authors.forename: Luc
authors.initials: L
authors.lastname: Paillard
authors.affiliation: Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et Développement, UMR6290, Rennes, France.
authors.forename: Yann
authors.initials: Y
authors.lastname: Audic
keywords: Alternative splicing; CLIP-seq; CUGBP1; Homo sapiens; RNA binding proteins