title: Clinical Predictors of Sensorineural Hearing Loss and Cognitive Outcome in Infants with Symptomatic Congenital Cytomegalovirus Infection.
abstract: The objective of this study was to determine newborn clinical findings predictive of adverse clinical outcomes in infants with symptomatic congenital cytomegalovirus infection. Of 160 infants, significantly more children with central nervous system involvement had sensorineural hearing loss (P = 0.0007) and an IQ ≤70 (P < 0.0001) compared with infants with transient findings or only a petechial rash.
authors.affiliation: From the *Division of General Pediatrics, Department of Pediatrics, University of Nebraska Medical Center/Children's Hospital and Medical Center, Omaha, Nebraska; †Division of Neonatology, Department of Pediatrics, Brookwood Medical Center, Birmingham, Alabama; and; ‡Division of Pediatric Infectious Diseases, Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama.
authors.forename: Swetha G
authors.initials: SG
authors.lastname: Pinninti
authors.forename: Mackenzie D
authors.initials: MD
authors.lastname: Rodgers
authors.forename: Zdenek
authors.initials: Z
authors.lastname: Novak
authors.forename: William J
authors.initials: WJ
authors.lastname: Britt
authors.forename: Karen B
authors.initials: KB
authors.lastname: Fowler
authors.forename: Suresh B
authors.initials: SB
authors.lastname: Boppana
authors.forename: Shannon A
authors.initials: SA
authors.lastname: Ross
mesh_terms: D003071:Cognition; D003587:Cytomegalovirus; D003586:Cytomegalovirus Infections / Q000150:complications* / Q000151:congenital / Q000453:epidemiology*; D006319:Hearing Loss, Sensorineural / Q000453:epidemiology* / Q000209:etiology*; D006801:Humans; D007231:Infant, Newborn; D008137:Longitudinal Studies; D012307:Risk Factors