title: Running induces nausea in rats: Kaolin intake generated by voluntary and forced wheel running.
abstract: Three experiments were conducted showing rats' pica behavior (kaolin clay intake) due to running in activity wheels. The amount of kaolin consumed was a positive function of the available time of voluntary running (20, 40, or 60 min), although this relationship was blunted by a descending (i.e., 60 → 40 → 20 min) test series of execution (Experiment 1). Pica was also generated by forced running in a motorized wheel for 60 min as a positive function of the speed of wheel rotations at 98, 185, or 365 m/h, independent of the order of execution (Experiment 2). Voluntary running generated more pica than did forced running at 80 m/h, although the distance travelled in the former condition was 27% lesser than that in the latter condition (Experiment 3). Because kaolin intake is regarded as a reliable measure of nausea in rats, these results show that wheel running, either voluntary or forced, induces nausea in rats.
authors.affiliation: Department of Psychological Science, Kwansei Gakuin University, Nishinomiya, 662-8501, Japan. Electronic address: nakajima@kwansei.ac.jp.
authors.forename: Sadahiko
authors.initials: S
authors.lastname: Nakajima
mesh_terms: D000538:Aluminum Silicates / Q000008:administration & dosage; D000818:Animals; D001522:Behavior, Animal; D000077215:Clay; D004195:Disease Models, Animal; D002149:Energy Intake; D005247:Feeding Behavior; D007616:Kaolin / Q000008:administration & dosage*; D008297:Male; D009043:Motor Activity; D009325:Nausea / Q000209:etiology* / Q000517:prevention & control; D005082:Physical Exertion; D010842:Pica / Q000503:physiopathology*; D017208:Rats, Wistar; D015203:Reproducibility of Results; D013997:Time Factors
chemical_list: D000538:Aluminum Silicates; D007616:Kaolin; D000077215:Clay
keywords: Kaolin; Pica; Rats; Wheel running