title: The Association Between Complementary and Alternative Medicine and Health Status Following Acute Myocardial Infarction.
abstract: BACKGROUND
  Complementary and alternative medicines (CAM) are commonly used in patients with cardiovascular disease. Although there is lack of evidence regarding the benefit of CAM on cardiovascular morbidity and mortality, health-status benefits could justify CAM use.
  
  
  OBJECTIVE
  Adoption of mind-body CAM after acute myocardial infarction (AMI) is associated with improved health status, though other forms of CAM are not associated with health-status improvement.
  
  
  METHODS
  Patients with AMI from 24 US sites were assessed for CAM use (categorized as mind-body, biological, and manipulative therapies) prior to and 1 year after AMI. Among patients who reported not using CAM prior to their AMI, association of initiating CAM on patients' health status at 1 year after AMI was assessed using Angina Frequency and Quality of Life domains from the Seattle Angina Questionnaire and the Short Form-12 Physical and Mental Component scales. Multivariable regression helped examine association between use of different CAM therapies and health status.
  
  
  RESULTS
  Among 1884 patients not using CAM at the time of their AMI, 33% reported initiating ≥1 forms of CAM therapy 1 year following AMI: 62% adopted mind-body therapies, 42% adopted biological therapies, and 15% began using manipulative therapies. In both unadjusted and adjusted analyses, we found no association between different types of CAM use and health-status improvement after AMI.
  
  
  CONCLUSIONS
  There was no association between CAM use and health-status recovery after AMI. Until randomized trials suggest otherwise, these findings underscore the importance of focusing on therapies with proven effectiveness after AMI.
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.|Department of Cardiology, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.|Department of Cardiology, Children's Mercy Hospital and Clinics, Kansas City, Missouri.
authors.forename: Ali
authors.initials: A
authors.lastname: Shafiq
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.
authors.forename: Natalie
authors.initials: N
authors.lastname: Jayaram
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.
authors.forename: Kensey L
authors.initials: KL
authors.lastname: Gosch
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.|Department of Cardiology, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.|Department of Cardiology, Children's Mercy Hospital and Clinics, Kansas City, Missouri.
authors.forename: John A
authors.initials: JA
authors.lastname: Spertus
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.|Department of Cardiology, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.|Department of Cardiology, Children's Mercy Hospital and Clinics, Kansas City, Missouri.
authors.forename: Donna M
authors.initials: DM
authors.lastname: Buchanan
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.|Department of Cardiology, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.
authors.forename: Carole
authors.initials: C
authors.lastname: Decker
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.|Department of Cardiology, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.|Department of Cardiology, Children's Mercy Hospital and Clinics, Kansas City, Missouri.
authors.forename: Mikhail
authors.initials: M
authors.lastname: Kosiborod
authors.affiliation: Cardiovascular Outcomes Research, Saint Luke's Mid America Heart Institute, Kansas City, Missouri.|Department of Cardiology, School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri.|Department of Cardiology, Children's Mercy Hospital and Clinics, Kansas City, Missouri.
authors.forename: Suzanne V
authors.initials: SV
authors.lastname: Arnold
mesh_terms: D000368:Aged; D001691:Biological Therapy / Q000009:adverse effects; D016009:Chi-Square Distribution; D005260:Female; D006304:Health Status; D006801:Humans; D016014:Linear Models; D016015:Logistic Models; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D026441:Mind-Body Therapies / Q000009:adverse effects; D015999:Multivariate Analysis; D026201:Musculoskeletal Manipulations / Q000009:adverse effects; D009203:Myocardial Infarction / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D011788:Quality of Life; D012042:Registries; D011795:Surveys and Questionnaires; D013997:Time Factors; D016896:Treatment Outcome; D014481:United States