title: Multi-tone suppression of distortion-product otoacoustic emissions in humans.
abstract: The purpose of this study was to investigate the combined effect of multiple suppressors. Distortion-product otoacoustic emission (DPOAE) measurements were made in normal-hearing participants. Primary tones had fixed frequencies (f2 = 4000 Hz; f1 / f2 = 1.22) and a range of levels. Suppressor tones were at three frequencies (fs = 2828, 4100, 4300 Hz) and range of levels. Decrement was defined as the attenuation in DPOAE level due to the presence of a suppressor. A measure of suppression called suppressive intensity was calculated by an equation previously shown to fit DPOAE suppression data. Suppressor pairs, which were the combination of two different frequencies, were presented at levels selected to have equal single-suppressor decrements. A hybrid model that represents a continuum between additive intensity and additive attenuation best described the results. The suppressor pair with the smallest frequency ratio produced decrements that were more consistent with additive intensity. The suppressor pair with the largest frequency ratio produced decrements at the highest level that were consistent with additive attenuation. Other suppressor-pair conditions produced decrements that were intermediate between these two alternative models. The hybrid model provides a useful framework for representing the observed range of interaction when two suppressors are combined.
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA.
authors.forename: Nicole E
authors.initials: NE
authors.lastname: Sieck
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA.
authors.forename: Daniel M
authors.initials: DM
authors.lastname: Rasetshwane
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA.
authors.forename: Judy G
authors.initials: JG
authors.lastname: Kopun
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA.
authors.forename: Walt
authors.initials: W
authors.lastname: Jesteadt
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA.
authors.forename: Michael P
authors.initials: MP
authors.lastname: Gorga
authors.affiliation: Boys Town National Research Hospital, 555 North 30th Street, Omaha, Nebraska 68131, USA.
authors.forename: Stephen T
authors.initials: ST
authors.lastname: Neely
mesh_terms: D000161:Acoustic Stimulation; D000328:Adult; D001299:Audiometry; D001307:Auditory Perception; D006801:Humans; D008875:Middle Aged; D009622:Noise / Q000009:adverse effects*; D017084:Otoacoustic Emissions, Spontaneous; D010470:Perceptual Masking; D055815:Young Adult