title: Fatal methotrexate toxicity in a patient treated for an ectopic pregnancy.
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia.
authors.forename: Emna
authors.initials: E
authors.lastname: Gaïes
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia. Electronic address: mouna.bs@hotmail.fr.
authors.forename: Mouna
authors.initials: M
authors.lastname: Ben Sassi
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia.
authors.forename: Rim
authors.initials: R
authors.lastname: Charfi
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Lakhal
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia.
authors.forename: Anis
authors.initials: A
authors.lastname: Klouz
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia.
authors.forename: Sameh
authors.initials: S
authors.lastname: Trabelsi
authors.affiliation: Department of clinical pharmacology, national centre of pharmacovigilance, 9, avenue Dr. Zouheir Essafi, 1006 Tunis, Tunisia.
authors.forename: Issam
authors.initials: I
authors.lastname: Salouage
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage / Q000009:adverse effects*; D000328:Adult; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D007273:Injections, Intramuscular; D008727:Methotrexate / Q000008:administration & dosage / Q000009:adverse effects*; D010198:Pancytopenia / Q000139:chemically induced*; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000188:drug therapy*
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate
keywords: Ectopic pregnancy; Effets indésirables; Grossesse extra-utérine; Methotrexate; Méthotrexate; Side effects; Suivi thérapeutique pharmacologique; Therapeutic drug monitoring; Toxicity; Toxicité