title: Lessons from the Bone Chapter of the Malaysian Aging Men Study.
abstract: Male osteoporosis in Malaysia is a largely neglected problem. Therefore, a bone health study in men using quantitative ultrasonometry was launched as part of the Malaysian Aging Men Study in 2009-2012. This review aimed to summarize the findings of the aforementioned bone health study. The study examined the bone health of Chinese and Malaysian men aged 20 years and above living in Kuala Lumpur using a quantitative ultrasound device. Participants answered a questionnaire on their demographic details and physical activity status. Body anthropometry of the participants was measured and their blood collected for biochemical analysis. Results showed that a significant proportion of the Malaysian Chinese and Malay men had suboptimal bone health indicated by calcaneal speed of sound and vitamin D status. Age-related decline of the calcaneal speed of sound in these men was gradual and biphasic without ethnic difference. Body anthropometry such as height, weight, body mass index, and body fat percentage contributed to the variation of the calcaneal speed of sound in Malaysian men. Age-related changes in testosterone, insulin-like growth factor 1, and thyroid stimulating hormone also influenced the calcaneal speed of sound in these men. This study serves as a reminder that male osteoporosis in Malaysia should be an issue of concern. It is also a basis for a more comprehensive study on bone health in men in the future.
authors.affiliation: Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia. chinkokyong@ppukm.ukm.edu.my.
authors.forename: Kok-Yong
authors.initials: KY
authors.lastname: Chin
authors.affiliation: Department of Biochemistry, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia. wwanzurinah@yahoo.com.
authors.forename: Wan Zurinah
authors.initials: WZ
authors.lastname: Wan Ngah
authors.affiliation: Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur 56000, Malaysia. imasoel@ppukm.ukm.edu.my.
authors.forename: Soelaiman
authors.initials: S
authors.lastname: Ima-Nirwana
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000375:Aging / Q000208:ethnology; D000886:Anthropometry; D002111:Calcaneus / Q000000981:diagnostic imaging / Q000502:physiology*; D003430:Cross-Sectional Studies; D006304:Health Status; D006801:Humans; D008296:Malaysia; D008297:Male; D008875:Middle Aged; D014463:Ultrasonography; D014807:Vitamin D / Q000097:blood*; D055815:Young Adult
chemical_list: D014807:Vitamin D
keywords: body mass index; bone; osteopenia; osteoporosis; testosterone; thyroids; vitamin D