title: Graftless sinus augmentation with simultaneous dental implant placement: clinical results and biological perspectives.
abstract: After a sinus lifting procedure, the compartment around the implants under the sinus mucosal lining in the sinus floor is filled with a blood clot from surrounding bleeding. The aim of this study was to evaluate the feasibility of bone formation following graftless sinus lifting with the simultaneous placement of dental implants. Thirty graftless sinus lifting procedures were performed and 72 dental implants placed in 18 consecutive patients, using the lateral window approach. Clinical and radiological follow-up was conducted throughout the 6-month healing period. Biopsies of 30 cases were collected at 6 months post-treatment: 15 biopsies were taken from the newly formed bone near the basal floor and 15 from the newly formed bone near the elevated membrane. New bone consolidation in the maxillary sinus was apparent radiologically and histologically at 6 months after sinus augmentation, providing an average 6.14±1.34mm of bone-gain. Based on histological analysis and histomorphometric data, the consolidated bone in the augmented sinus comprised 56.7±11.9% to 59.9±13.4% vital bone tissue. Out of the 72 implants placed, only four failed, indicating a 94% overall implant survival rate. Based on this case series, blood clot can be considered autologous osteogenic graft material, to which osteoprogenitors can migrate, differentiate, and regenerate bone.
authors.affiliation: Eliachar Research Laboratory, Western Galilee Hospital, Nahariya, Israel.
authors.forename: M
authors.initials: M
authors.lastname: Falah
authors.affiliation: Department of Dentistry and Oral and Maxillofacial Surgery, Daegu Catholic University Hospital, Daegu, Republic of Korea.
authors.forename: D-S
authors.initials: DS
authors.lastname: Sohn
authors.affiliation: Oral and Maxillofacial Institute, Galilee Medical Center, Nahariya, Israel; Faculty of Medicine in the Galilee, Bar-Ilan University, Ramat Gan, Tel Aviv, Israel. Electronic address: dr.samersrouji@gmail.com.
authors.forename: S
authors.initials: S
authors.lastname: Srouji
mesh_terms: D000328:Adult; D003758:Dental Implantation, Endosseous; D015921:Dental Implants; D019232:Dental Restoration Failure / Q000706:statistics & numerical data; D005240:Feasibility Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008443:Maxillary Sinus / Q000000981:diagnostic imaging* / Q000502:physiology; D008875:Middle Aged; D010012:Osteogenesis; D059546:Sinus Floor Augmentation / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants
keywords: Schneiderian membrane; fibrin clot; maxillary sinus; sinus lifting