title: Pulmonary Tumor Thrombotic Microangiopathy: A New Paraneoplastic Syndrome?
abstract: This report, based on data from a clinical case, proposes that pulmonary tumor thrombotic microangiopathy, an underdiagnosed cause of pulmonary hypertension and death in patients with adenocarcinoma, is a paraneoplastic syndrome (PNS). Clinicians in general must be alert to the presence or development of PNS that may precede, coincide with, follow, or herald the recurrence or the primary diagnosis of malignancy since early recognition facilitates prompt diagnosis and treatment.
authors.affiliation: Murtha Cancer Center, Walter Reed National Military Medical Center, Bethesda, Md., USA.
authors.forename: Corey A
authors.initials: CA
authors.lastname: Carter
authors.affiliation: EpicentRx Inc., Mountain View, Calif., USA.
authors.forename: Jan J
authors.initials: JJ
authors.lastname: Scicinski
authors.affiliation: Department of Physiology, Helsinki University, Helsinki, Finland.
authors.forename: Harry E
authors.initials: HE
authors.lastname: Lybeck
authors.affiliation: EpicentRx Inc., Mountain View, Calif., USA.
authors.forename: Bryan T
authors.initials: BT
authors.lastname: Oronsky
keywords: Adenocarcinoma; Diagnosis; Paraneoplastic syndrome; Pulmonary tumor thrombotic microangiopathy