title: Peritoneal dialysis use within the context of the population and healthcare systems of Europe - differences, trends and future challenges.
abstract: BACKGROUND
  Peritoneal dialysis (PD) and haemodialysis (HD) are complementary therapies in end-stage renal disease (ESRD). Despite survival benefit, PD remains an underused therapy with variable utilisation and a common descriptive framework for this variation is not established. We reviewed the renal literature, general population and healthcare data to examine factors leading to variable PD use in Europe and possible changes in the future.
  
  
  METHODS
  ERA-EDTA data were used to examine PD distribution in Europe. Statistics and descriptive data about population structure and living conditions published by Eurostat, the World Health Organization (WHO) and the European Observatory were examined. Published literature (Pubmed), health system data (formal internet search approach) and professional body data (internet and personal communication) were examined to describe the factors that may explain PD variation.
  
  
  RESULTS
  PD usage varies across Europe and analysis of contributing factors enabled the development of a descriptive framework. PD variation cannot be entirely explained by the reimbursement system. It appears that factors specific to countries and centres as well as personalised ones involving patient-physician interaction are the most influential. The current and projected European population demographics and living conditions will lead to more elderly patients who live alone being on dialysis.
  
  
  CONCLUSIONS
  Factors relating to the patient-physician interaction are prime determinants around the utilization of PD. Population demographic change will lead to additional challenges to renal services. The descriptive framework postulated should be considered in strategic dialysis service planning and future product design to meet the needs of future dialysis patients and deliver patient choice.
authors.affiliation: Karolinska Insitutet, Stockholm - Sweden.|Baxter Medical AB, Kista - Sweden.
authors.forename: Anna
authors.initials: A
authors.lastname: Machowska
authors.affiliation: Quintiles, Reading - UK.|Glyndwr University, Wrexham - UK.
authors.forename: Peter
authors.initials: P
authors.lastname: Rutherford
mesh_terms: D005060:Europe; D006801:Humans; D007676:Kidney Failure, Chronic / Q000628:therapy*; D018579:Patient Selection; D010530:Peritoneal Dialysis / Q000706:statistics & numerical data* / Q000639:trends; D006435:Renal Dialysis / Q000706:statistics & numerical data* / Q000639:trends