title: Development and Implementation of Sepsis Alert Systems.
abstract: Development and implementation of sepsis alert systems is challenging, particularly outside the monitored intensive care unit (ICU) setting. Barriers to wider use of sepsis alerts include evolving clinical definitions of sepsis, information overload, and alert fatigue, due to suboptimal alert performance. Outside the ICU, barriers include differences in health care delivery models, charting behaviors, and availability of electronic data. Current evidence does not support routine use of sepsis alert systems in clinical practice. Continuous improvement in the afferent and efferent aspects will help translate theoretic advantages into measurable patient benefit.
authors.affiliation: Medical Scientist Training Program, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Harrison
authors.affiliation: Division of Pulmonology and Critical Care Medicine, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
authors.forename: Ognjen
authors.initials: O
authors.lastname: Gajic
authors.affiliation: Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA.
authors.forename: Brian W
authors.initials: BW
authors.lastname: Pickering
authors.affiliation: Department of Anesthesiology, Mayo Clinic, 200 First Street Southwest, Rochester, MN 55905, USA. Electronic address: Herasevich.Vitaly@mayo.edu.
authors.forename: Vitaly
authors.initials: V
authors.lastname: Herasevich
mesh_terms: D006801:Humans; D007362:Intensive Care Units / Q000592:standards*; D018805:Sepsis / Q000628:therapy*
keywords: Automated alert systems; Critical care; Hospital; Intensive care unit; Sepsis