title: Does impulsivity predict outcome in treatment for binge eating disorder? A multimodal investigation.
abstract: Multiple dimensions of impulsivity (e.g., affect-driven impulsivity, impulsive inhibition - both general and food-specific, and impulsive decision-making) are associated with binge eating pathology cross-sectionally, yet the literature on whether impulsivity predicts treatment outcome is limited. The present pilot study explored impulsivity-related predictors of 20-week outcome in a small open trial (n = 17) of a novel treatment for binge eating disorder. Overall, dimensions of impulsivity related to emotions (i.e., negative urgency) and food cues emerged as predictors of treatment outcomes (i.e., binge eating frequency and global eating pathology as measured by the Eating Disorders Examination), while more general measures of impulsivity were statistically unrelated to global eating pathology or binge frequency. Specifically, those with higher levels of negative urgency at baseline experienced slower and less pronounced benefit from treatment, and those with higher food-specific impulsivity had more severe global eating pathology at baseline that was consistent at post-treatment and follow-up. These preliminary findings suggest that patients high in negative urgency and with poor response inhibition to food cues may benefit from augmentation of existing treatments to achieve optimal outcomes. Future research will benefit from replication with a larger sample, parsing out the role of different dimensions of impulsivity in treatment outcome for eating disorders, and identifying how treatment can be improved to accommodate higher levels of baseline impulsivity.
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA. Electronic address: smm522@drexel.edu.
authors.forename: Stephanie M
authors.initials: SM
authors.lastname: Manasse
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA.
authors.forename: Hallie M
authors.initials: HM
authors.lastname: Espel
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA.
authors.forename: Leah M
authors.initials: LM
authors.lastname: Schumacher
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA.
authors.forename: Stephanie G
authors.initials: SG
authors.lastname: Kerrigan
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA.
authors.forename: Fengqing
authors.initials: F
authors.lastname: Zhang
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA.
authors.forename: Evan M
authors.initials: EM
authors.lastname: Forman
authors.affiliation: Drexel University, Department of Psychology, Philadelphia, PA, USA.
authors.forename: Adrienne S
authors.initials: AS
authors.lastname: Juarascio
mesh_terms: D064869:Acceptance and Commitment Therapy; D000328:Adult; D056912:Binge-Eating Disorder / Q000175:diagnosis / Q000503:physiopathology / Q000523:psychology / Q000628:therapy*; D003131:Combined Modality Therapy; D003463:Cues; D065786:Delay Discounting; D039721:Diagnostic and Statistical Manual of Mental Disorders; D005260:Female; D005500:Follow-Up Studies; D005518:Food Preferences / Q000523:psychology; D006801:Humans; D007175:Impulsive Behavior; D008875:Middle Aged; D010865:Pilot Projects; D011379:Prognosis; D011569:Psychiatric Status Rating Scales; D011615:Psychotherapy, Group; D057566:Self Report; D000068356:Self-Control; D012720:Severity of Illness Index; D014481:United States; D055815:Young Adult
keywords: Binge eating; Impulsivity; Inhibitory control; Negative urgency