title: Treatment of Intramyometrial Pregnancy by In Situ Injection of Methotrexate.
abstract: Intramyometrial ectopic pregnancies are rare, and various management modalities have been described. We report a patient with intramyometrial pregnancy who was successfully treated by in situ injection of methotrexate (MTX) after the failure of 2 intramuscular injections of MTX. We emphasize the difficult management of intramyometrial pregnancy and show that in situ MTX injection may be indicated for this particular type of ectopic pregnancy.
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Medicine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France. Electronic address: drcohenjonathan@gmail.com.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Cohen
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Medicine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Kamila
authors.initials: K
authors.lastname: Kolanska
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Medicine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Anne-Sophie
authors.initials: AS
authors.lastname: Zanini-Grandon
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Medicine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Jeremie
authors.initials: J
authors.lastname: Belghiti
authors.affiliation: Department of Radiology, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Thomassin-Naggara
authors.affiliation: Department of Radiology, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Marc
authors.initials: M
authors.lastname: Bazot
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Medicine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Bornes
authors.affiliation: Department of Obstetrics, Gynecology, and Reproductive Medicine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, GRC6-UPMC, Centre Expert en Endométriose (C3E), UMR S938, Université Pierre et Marie Curie Paris 6, Paris, France.
authors.forename: Emile
authors.initials: E
authors.lastname: Daraï
mesh_terms: D000020:Abortifacient Agents, Nonsteroidal / Q000008:administration & dosage; D000328:Adult; D005260:Female; D006801:Humans; D015552:Injections, Intralesional / Q000379:methods; D007273:Injections, Intramuscular; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008727:Methotrexate / Q000008:administration & dosage*; D009215:Myometrium / Q000000981:diagnostic imaging / Q000473:pathology; D011247:Pregnancy; D011271:Pregnancy, Ectopic / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology; D016896:Treatment Outcome; D014463:Ultrasonography / Q000379:methods*
chemical_list: D000020:Abortifacient Agents, Nonsteroidal; D008727:Methotrexate
keywords: Ectopic pregnancy; In situ methotrexate injection; Intramyometrial pregnancy