title: Thyroid Cancer in Pediatrics.
abstract: Well differentiated thyroid cancer (DTC) in children is characterized by a high rate of response to treatment and low disease-specific mortality. Treatment of children with DTC has evolved toward a greater reliance on evaluation and monitoring with serial serum thyroglobulin measurements and ultrasound examinations. Radioiodine therapy is recommended for thyroid remnant ablation in high-risk patients, treatment of demonstrated radioiodine-avid local-regional disease not amenable to surgical resection, or distant radioiodine-avid metastatic disease. Sufficient time should be given for benefits of radioiodine therapy to be realized, with follow-up monitoring. Re-treatment with radioiodine can be deferred until progression of significant disease manifests.
authors.affiliation: Nuclear Medicine, Mount Sinai Medical Center, Icahn School of Medicine at Mount Sinai, Box 1141, 1 Gustave Levy Place, New York, NY 10029, USA. Electronic address: josef.machac@mssm.edu.
authors.forename: Josef
authors.initials: J
authors.lastname: Machac
mesh_terms: D002648:Child; D006801:Humans; D007457:Iodine Radioisotopes / Q000627:therapeutic use; D010372:Pediatrics; D013960:Thyroid Function Tests; D013964:Thyroid Neoplasms / Q000175:diagnosis* / Q000628:therapy*
chemical_list: D007457:Iodine Radioisotopes
keywords: Diagnosis; Pediatric; Risk-stratification; Staging; Therapy; Thyroid cancer