title: Enhancing Care of the Survivor of Gynecologic Cancer: Managing the Menopause and Radiation Toxicity.
abstract: It is expected that there will be 290,000 cases of gynecologic cancers in 2016. Of these cancers, 60,000 will be endometrial and 22,000 will be ovarian-the two most common gynecologic cancers. Endometrial and ovarian cancers occur in menopausal women with mean ages of 60 and 63, respectively. The majority of endometrial cancers are early stage, and 5-year survival is considered good at upwards of 75%. For ovarian cancer, while survival rates have improved, the 5-year survival rate for the most common stage (stage III) is 40%. Thus, a substantial number of patients with gynecologic cancer are menopausal, and a significant number of patients are survivors, particularly of endometrial cancers. It will be important for survivors of gynecologic cancers to receive care tailored to their needs as women and to mitigate gender-specific side effects of their cancer treatment.
authors.affiliation: From the Division of Gynecologic Oncology, University of North Carolina School of Medicine, Chapel Hill, NC; University College Hospital, London, United Kingdom.
authors.forename: Linda
authors.initials: L
authors.lastname: Van Le
authors.affiliation: From the Division of Gynecologic Oncology, University of North Carolina School of Medicine, Chapel Hill, NC; University College Hospital, London, United Kingdom.
authors.forename: Mary
authors.initials: M
authors.lastname: McCormack
mesh_terms: D005260:Female; D005833:Genital Neoplasms, Female / Q000473:pathology / Q000532:radiotherapy*; D006801:Humans; D008593:Menopause / Q000528:radiation effects; D008875:Middle Aged; D009376:Neoplasms, Hormone-Dependent / Q000473:pathology / Q000532:radiotherapy*; D010388:Pelvis / Q000473:pathology / Q000528:radiation effects; D011878:Radiotherapy / Q000009:adverse effects*; D017741:Survivors