title: The Effect of Stevia on the Chicken Embryo Heart.
abstract: Stevioside is one of the most important food additives that has become well known for its sweetness. The aim of this study was to evaluate the impact of Stevioside on the heart.
  
  
  
  4-day-old embryonated chickens eggs were inoculated with Stevioside and kept until hatching. Shortly after, the heart tissue samples were taken to examine organ Oxidative stresses by measuring Malondialdehyde (MDA) and glutathione (GSH) levels, ferric reducing /antioxidant power (FRAP) and cupric ion reducing assay (CUPRIC).
  
  
  
  There was no significant difference in glutathione level, lipid peroxidation, FRAP, and cupric assay.
  
  
  
  It was suggested that stevioside did not cause marked damages to heart tissues in chicken embryo model.
authors.affiliation: School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
authors.forename: Parisa
authors.initials: P
authors.lastname: Sadighara
authors.forename: Isa
authors.initials: I
authors.lastname: Mohammadpour
authors.forename: Mahdi
authors.initials: M
authors.lastname: Jahanbakhsh
authors.forename: Atefeh
authors.initials: A
authors.lastname: Araghi
authors.forename: Ahmad
authors.initials: A
authors.lastname: Nazaktabar
mesh_terms: D000818:Animals; D002642:Chick Embryo / Q000187:drug effects* / Q000196:embryology / Q000378:metabolism; D002645:Chickens; D045786:Diterpenes, Kaurane / Q000737:chemistry / Q000494:pharmacology*; D005960:Glucosides / Q000737:chemistry / Q000494:pharmacology*; D005978:Glutathione / Q000378:metabolism; D006321:Heart / Q000187:drug effects* / Q000196:embryology*; D015227:Lipid Peroxidation / Q000187:drug effects; D008315:Malondialdehyde / Q000378:metabolism; D018384:Oxidative Stress / Q000187:drug effects*; D036625:Stevia / Q000737:chemistry; D013549:Sweetening Agents / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D045786:Diterpenes, Kaurane; D005960:Glucosides; D013549:Sweetening Agents; C012043:stevioside; D008315:Malondialdehyde; D005978:Glutathione