title: Nuclear bodies: Built to boost.
abstract: The classic archetypal function of nuclear bodies is to accelerate specific reactions within their crowded space. In this issue, Tatomer et al. (2016. J. Cell Biol http://dx.doi.org/10.1083/jcb.201504043) provide the first direct evidence that the histone locus body acts to concentrate key factors required for the proper processing of histone pre-mRNAs.
authors.affiliation: Department of Cell Biology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064 Laboratory of Receptor Biology and Gene Expression, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892.
authors.forename: Iain A
authors.initials: IA
authors.lastname: Sawyer
authors.affiliation: Department of Cell Biology, Rosalind Franklin University of Medicine and Science, Chicago Medical School, North Chicago, IL 60064 mirek.dundr@rosalindfranklin.edu.
authors.forename: Miroslav
authors.initials: M
authors.lastname: Dundr
mesh_terms: D000818:Animals; D004331:Drosophila melanogaster / Q000378:metabolism; D006657:Histones / Q000378:metabolism; D006801:Humans; D045586:Intranuclear Inclusion Bodies / Q000378:metabolism*; D008954:Models, Biological; D012313:RNA / Q000378:metabolism; D020885:Ribonucleoprotein, U7 Small Nuclear / Q000378:metabolism
chemical_list: D006657:Histones; D020885:Ribonucleoprotein, U7 Small Nuclear; D012313:RNA