title: Primary hyperparathyroidism in pregnancy: a case series and literature review.
abstract: Primary Hyperparathyroidism (PHP) in pregnancy constitutes a serious danger to mother and fetus. The diagnosis of PHP in pregnancy presents a challenge, and PHP commonly goes unidentified and untreated in pregnancy. We present four case reports about patients having PHP, which is very rare condition in pregnancy and their treatment modalities. Three patients, not to be controlled biochemically, denied the parathyroidectomy operation although they are informed about the details of their disease. They are followed up with medical therapy. The first one had no maternal or fetal complications, the second one acquired nephrolithiasis crisis in the last trimester and the third one gave birth to a premature baby who succumbed to tetany. The fourth patient who underwent parathyroidectomy operation in the second trimester had no maternal or fetal complications. PHP in pregnancy is a preventable cause of fetal and maternal mortality and morbidity. Thus, suspecting from PHP during the pregnancy and early diagnosis is critically important in terms of maternal and fetal wellness.
authors.affiliation: a Department of Internal Medicine , Division of Endocrinology and Metabolism, Faculty of Medicine , Central Campus , University of Ataturk , Erzurum , Turkey.
authors.forename: Naile
authors.initials: N
authors.lastname: Gokkaya
authors.affiliation: b Department of Internal Medicine , Division of Endocrinology and Metabolism, Faculty of Medicine, University of Ataturk , Erzurum , Turkey , and.
authors.forename: Adem
authors.initials: A
authors.lastname: Gungor
authors.affiliation: c Department of Internal Medicine , Faculty of Medicine, University of Ataturk , Erzurum , Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Bilen
authors.affiliation: b Department of Internal Medicine , Division of Endocrinology and Metabolism, Faculty of Medicine, University of Ataturk , Erzurum , Turkey , and.
authors.forename: Habib
authors.initials: H
authors.lastname: Bilen
authors.affiliation: b Department of Internal Medicine , Division of Endocrinology and Metabolism, Faculty of Medicine, University of Ataturk , Erzurum , Turkey , and.
authors.forename: Darina
authors.initials: D
authors.lastname: Gviniashvili
authors.affiliation: b Department of Internal Medicine , Division of Endocrinology and Metabolism, Faculty of Medicine, University of Ataturk , Erzurum , Turkey , and.
authors.forename: Yusuf
authors.initials: Y
authors.lastname: Karadeniz
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000150:complications / Q000178:diet therapy / Q000601:surgery; D016105:Parathyroidectomy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000178:diet therapy / Q000601:surgery; D011256:Pregnancy Outcome
keywords: Hypercalcemia; hyperparathyroidism; pregnancy