title: Radiation-Induced Problems in Colorectal Surgery.
abstract: Radiotherapy not only plays a pivotal role in the cancer care pathways of many patients with pelvic malignancies, but can also lead to significant injury of normal tissue in the radiation field (pelvic radiation disease) that is sometimes as challenging to treat as the neoplasms themselves. Acute symptoms are usually self-limited and respond to medical therapy. Chronic symptoms often require operative intervention that is made hazardous by hostile surgical planes and unforgiving tissues. Management of these challenging patients is best guided by the utmost caution and humility.
authors.affiliation: Department of Colorectal Surgery, Digestive Diseases Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
authors.forename: Jean H
authors.initials: JH
authors.lastname: Ashburn
authors.affiliation: Department of Colorectal Surgery, Digestive Diseases Institute, Cleveland Clinic Foundation, Cleveland, Ohio.
authors.forename: Matthew F
authors.initials: MF
authors.lastname: Kalady
keywords: radiation enteritis or enteropathy; radiation proctitis; radiation-induced bowel damage