title: Optical configuration of pigmented lesion detection by frequency analysis of skin speckle patterns.
abstract: In this paper we present a novel approach of realizing a safe, simple, and inexpensive sensor applicable to pigmented lesions detection. The approach is based on temporal tracking of back-reflected secondary speckle patterns generated while illuminating the affected area with a laser and applying periodic pressure to the surface via a controlled vibration source. When applied to pigmented lesions, the technique is superior to visual examination in avoiding many false positives and resultant unnecessary biopsies. Applying a series of different vibration frequencies at the examined tissue and analyzing the 2-D time varying speckle patterns in response to the applied periodic pressure creates a unique signature for each and different pigmented lesion. Analyzing these signatures is the first step toward detection of malignant melanoma. In this paper we present preliminary experiments that show the validity of the developed sensor for the classification of pigmented lesions.
authors.affiliation: Faculty of Engineering and the Nano Technology Center, Bar-Ilan University, Ramat-Gan 52900, Israel; These authors contributed equally to the paper.
authors.forename: Yael
authors.initials: Y
authors.lastname: Bishitz
authors.affiliation: Faculty of Engineering and the Nano Technology Center, Bar-Ilan University, Ramat-Gan 52900, Israel; These authors contributed equally to the paper.
authors.forename: Nisan
authors.initials: N
authors.lastname: Ozana
authors.affiliation: Faculty of Engineering and the Nano Technology Center, Bar-Ilan University, Ramat-Gan 52900, Israel.
authors.forename: Ariel
authors.initials: A
authors.lastname: Schwarz
authors.affiliation: Faculty of Engineering and the Nano Technology Center, Bar-Ilan University, Ramat-Gan 52900, Israel.
authors.forename: Yevgeny
authors.initials: Y
authors.lastname: Beiderman
authors.affiliation: Departamento de O ´ptica, Universitat de46100 Burjassot, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Garcia
authors.affiliation: Faculty of Engineering and the Nano Technology Center, Bar-Ilan University, Ramat-Gan 52900, Israel.
authors.forename: Zeev
authors.initials: Z
authors.lastname: Zalevsky
keywords: (030.6140) Speckle; (170.0170) Medical optics and biotechnology; (280.0280) Remote sensing and sensors