title: Extending the Substrate Scope for the Asymmetric Iridium-Catalyzed Hydrogenation of Minimally Functionalized Olefins by Using Biaryl Phosphite-Based Modular Ligand Libraries.
abstract: Asymmetric hydrogenation is one of the most efficient and atom-economical tools to prepare chiral molecules. However, the enantiodiscrimination of simple, minimally functionalized olefins is still challenging and requires more sophisticated ligand design. Herein, we discuss our progress in the successful development of ligand design for the iridium-catalyzed asymmetric hydrogenation of minimally functionalized olefins.
authors.affiliation: Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, C/Marcel·li Domingo, 1, 43007, Tarragona, Spain.
authors.forename: Oscar
authors.initials: O
authors.lastname: Pàmies
authors.affiliation: Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, C/Marcel·li Domingo, 1, 43007, Tarragona, Spain.
authors.forename: Marc
authors.initials: M
authors.lastname: Magre
authors.affiliation: Departament de Química Física i Inorgànica, Universitat Rovira i Virgili, C/Marcel·li Domingo, 1, 43007, Tarragona, Spain.
authors.forename: Montserrat
authors.initials: M
authors.lastname: Diéguez
keywords: P,N ligands; P,S ligands; hydrogenation; iridium; ligand design