title: Hypothyroidism Associated with Myeloid Neoplasia.
abstract: We report 2 cases of hypothyroidism in whom the associated haematological disturbances (macrocytic anaemia in both cases, mild leukopenia and thrombo-penia in one patient) failed to be corrected by thyroid hormone replacement therapy. Further investigations led to the diagnosis of acute myeloid leukaemia (AML) in the first patient and myelodysplasia syndrome (MDS) in the other. The reasons of the delayed diagnosis and the possible mechanisms explaining this rare combination are discussed. The hypothesis of a purely coincidental association seems most likely.
authors.affiliation: a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.
authors.forename: A L
authors.initials: AL
authors.lastname: Boonen
authors.affiliation: a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.
authors.forename: C
authors.initials: C
authors.lastname: Lefebvre
authors.affiliation: a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.
authors.forename: M
authors.initials: M
authors.lastname: Lambert
authors.affiliation: a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.
authors.forename: A
authors.initials: A
authors.lastname: Fcrrant
authors.affiliation: a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.
authors.forename: J L
authors.initials: JL
authors.lastname: Michaux
authors.affiliation: a Divisions of General Internal Medicine and Haematology* Saint-Luc University Hospital 10, avenue Hippocrate, B-1200 Brussels.
authors.forename: E
authors.initials: E
authors.lastname: Coche