title: [DRESS syndrome].
abstract: DRESS syndrome (Drug Rash with Eosinophilia and Systemic Symptoms) is severe drug-induced allergic-type reaction which occurs few days to weeks after taking a drug in a predisposed patient. Organ damage, eosinophilia and skin rash are typical at presentation. Corticotherapy is often necessary in severe cases. In this report we describe a case of 56-year old female with fever, elevated liver tests and skin rash. DRESS syndrome was diagnosed and allopurinol was indentified as a causative drug. Due to possible fatal outcome, DRESS syndrome should be considered in a differential diagnosis of all patients presenting with similar signs and symptoms.
authors.forename: Monika
authors.initials: M
authors.lastname: Adamcová
authors.forename: Igor
authors.initials: I
authors.lastname: Šturdík
authors.forename: Tomáš
authors.initials: T
authors.lastname: Koller
authors.forename: Juraj
authors.initials: J
authors.lastname: Payer
mesh_terms: D000493:Allopurinol / Q000009:adverse effects*; D003937:Diagnosis, Differential; D063926:Drug Hypersensitivity Syndrome / Q000175:diagnosis*; D004791:Enzyme Inhibitors / Q000009:adverse effects*; D005260:Female; D006801:Humans; D008875:Middle Aged
chemical_list: D004791:Enzyme Inhibitors; D000493:Allopurinol