title: Ophthalmologic aspects of chikungunya infection.
abstract: Chikungunya fever, a viral disease epidemic in some parts of the world is newly introduced in the Americas. This is of considerable international concern, with a growing incidence owing to developing urbanization, tourism, and trade. Ocular manifestations of chikungunya fever are not frequent, but of great relevance. Common manifestations include conjunctivitis, optic neuritis, iridocyclitis, episcleritis, retinitis and uveitis. Diagnostic and monitoring investigations would include optical coherence tomography, fundus fluorescein and indocyanine green angiography, visual field analysis, and electrophysiologic tests. There have been no prospective, randomized therapeutic trials, and it is unclear if the disease is self-limiting or if treatment is actually beneficial. Prognosis varies, ranging from full resolution to permanent vision loss despite intervention.
authors.affiliation: Research Group and Incubator Public Health and Infection, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Risaralda, Colombia.
authors.forename: Dayron F
authors.initials: DF
authors.lastname: Martínez-Pulgarín
authors.affiliation: Department of Medicine, Sylhet M. A. G. Osmani Medical College Hospital, Sylhet, Bangladesh.
authors.forename: Fazle Rabbi
authors.initials: FR
authors.lastname: Chowdhury
authors.affiliation: Infectious Diseases and Infection Control Research Group, Hospital Universitario de Sincelejo, Sincelejo, Sucre, Colombia; Programa del Doctorado de Medicina Tropical, Universidad de Cartagena, Cartagena, Universidad del Atlántico, Barranquilla, Colombia; Committee on Zoonoses and Haemorrhagic Fevers, Asociación Colombiana de Infectología (ACIN), Bogotá, DC, Colombia.
authors.forename: Wilmer E
authors.initials: WE
authors.lastname: Villamil-Gomez
authors.affiliation: Research Group and Incubator Public Health and Infection, Faculty of Health Sciences, Universidad Tecnologica de Pereira, Pereira, Risaralda, Colombia; Infectious Diseases and Infection Control Research Group, Hospital Universitario de Sincelejo, Sincelejo, Sucre, Colombia; Committee on Zoonoses and Haemorrhagic Fevers, Asociación Colombiana de Infectología (ACIN), Bogotá, DC, Colombia; Organización Latinoamericana para el Fomento de la Investigación en Salud (OLFIS), Bucaramanga, Santander, Colombia. Electronic address: arodriguezm@utp.edu.co.
authors.forename: Alfonso J
authors.initials: AJ
authors.lastname: Rodriguez-Morales
authors.affiliation: Department of Biology, University of Florida, Gainesville, FL, USA.
authors.forename: Gabriela M
authors.initials: GM
authors.lastname: Blohm
authors.affiliation: Department of Pathology and Laboratory Medicine, Hospital Internacional, Barquisimeto, Venezuela; Laboratory of Biochemistry, Instituto de Biomedicina/IVSS, Caracas, Venezuela.
authors.forename: Alberto E
authors.initials: AE
authors.lastname: Paniz-Mondolfi
mesh_terms: D000328:Adult; D065632:Chikungunya Fever / Q000097:blood / Q000150:complications* / Q000175:diagnosis* / Q000821:virology; D002646:Chikungunya virus / Q000302:isolation & purification; D005128:Eye Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000821:virology*; D005260:Female; D005347:Fibroblasts / Q000821:virology; D005451:Fluorescein Angiography; D006801:Humans; D008297:Male; D009902:Optic Neuritis / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D011379:Prognosis; D011446:Prospective Studies; D012173:Retinitis / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D041623:Tomography, Optical Coherence; D014605:Uveitis / Q000188:drug therapy / Q000209:etiology / Q000821:virology; D055815:Young Adult
keywords: Chikungunya; Complications; Optic neuritis; Retinitis; Uveitis