title: Electrochemical C-H/N-H Functionalization for the Synthesis of Highly Functionalized (Aza)indoles.
abstract: Indoles and azaindoles are among the most important heterocycles because of their prevalence in nature and their broad utility in pharmaceutical industry. Reported herein is an unprecedented noble-metal- and oxidant-free electrochemical method for the coupling of (hetero)arylamines with tethered alkynes to synthesize highly functionalized indoles, as well as the more challenging azaindoles.
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China.
authors.forename: Zhong-Wei
authors.initials: ZW
authors.lastname: Hou
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China.
authors.forename: Zhong-Yi
authors.initials: ZY
authors.lastname: Mao
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China.
authors.forename: Huai-Bo
authors.initials: HB
authors.lastname: Zhao
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China.
authors.forename: Yared Yohannes
authors.initials: YY
authors.lastname: Melcamu
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China. xinlu@xmu.edu.cn.
authors.forename: Xin
authors.initials: X
authors.lastname: Lu
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China.|Fujian Institute of Research on Structure of Matter, Chinese Academy of Sciences, Fuzhou, 350002, P.R. China.
authors.forename: Jinshuai
authors.initials: J
authors.lastname: Song
authors.affiliation: Collaborative Innovation Center of Chemistry for Energy Material, State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province and, Department of Chemistry, Xiamen University, Xiamen, 361005, P.R. China. haichao.xu@xmu.edu.cn.
authors.forename: Hai-Chao
authors.identifier: 0000-0002-3008-5143
authors.initials: HC
authors.lastname: Xu
keywords: electrochemistry; heterocycles; indoles; radicals; redox chemistry