title: The number of unrecognized myocardial infarction scars detected at DE-MRI increases during a 5-year follow-up.
abstract: OBJECTIVE
  In an elderly population, the prevalence of unrecognized myocardial infarction (UMI) scars found via late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) imaging was more frequent than expected. This study investigated whether UMI scars detected with LGE-CMR at age 70 would be detectable at age 75 and whether the scar size changed over time.
  
  
  METHODS
  From 248 participants that underwent LGE-CMR at age 70, 185 subjects underwent a follow-up scan at age 75. A myocardial infarction (MI) scar was defined as late enhancement involving the subendocardium.
  
  
  RESULTS
  In the 185 subjects that underwent follow-up, 42 subjects had a UMI scar at age 70 and 61 subjects had a UMI scar at age 75. Thirty-seven (88 %) of the 42 UMI scars seen at age 70 were seen in the same myocardial segment at age 75. The size of UMI scars did not differ between age 70 and 75.
  
  
  CONCLUSIONS
  The prevalence of UMI scars detected at LGE-CMR increases with age. During a 5-year follow-up, 88 % (37/42) of the UMI scars were visible in the same myocardial segment, reassuring that UMI scars are a consistent finding. The size of UMI scars detected during LGE-CMR did not change over time.
  
  
  CONCLUSIONS
  • UMI scars detected by LGE-CMR are frequent in elderly. • The prevalence of UMI scars detected with LGE-CMR increases with age. • UMI scar size does not change over time.
authors.affiliation: Department of Radiology, Uppsala University Hospital, 751 85, Uppsala, Sweden. espregueirathemudo@gmail.com.
authors.forename: Raquel
authors.initials: R
authors.lastname: Themudo
authors.affiliation: Department of Radiology, Uppsala University Hospital, 751 85, Uppsala, Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Johansson
authors.affiliation: Department of Radiology, Uppsala University Hospital, 751 85, Uppsala, Sweden.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Ebeling-Barbier
authors.affiliation: Department of Medicine, Uppsala University Hospital, 751 85, Uppsala, Sweden.
authors.forename: Lars
authors.initials: L
authors.lastname: Lind
authors.affiliation: Department of Radiology, Uppsala University Hospital, 751 85, Uppsala, Sweden.
authors.forename: Håkan
authors.initials: H
authors.lastname: Ahlström
authors.affiliation: Department of Radiology, Uppsala University Hospital, 751 85, Uppsala, Sweden.
authors.forename: Tomas
authors.initials: T
authors.lastname: Bjerner
mesh_terms: D000368:Aged; D058070:Asymptomatic Diseases; D002921:Cicatrix / Q000000981:diagnostic imaging* / Q000453:epidemiology; D003287:Contrast Media; D005260:Female; D005500:Follow-Up Studies; D005682:Gadolinium; D019786:Gadolinium DTPA; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D008297:Male; D009203:Myocardial Infarction / Q000000981:diagnostic imaging* / Q000453:epidemiology; D015995:Prevalence; D013548:Sweden / Q000453:epidemiology
chemical_list: D003287:Contrast Media; C064925:gadodiamide; D005682:Gadolinium; D019786:Gadolinium DTPA
keywords: Aged; Cicatrix; Epidemiology; Magnetic resonance imaging; Myocardium