title: The impact of BMI on early colorectal neoplastic lesions and the role of endoscopic diagnosis:. An Italian observational study.
abstract: BACKGROUND
  CRC often arises from polyps: an early detection and resection are effective in decreasing both incidence and mortality rate. Relation between risk factors, adenomas and CRC have been showed, but there is little evidence for overweight association with preneoplastic lesions. This study analyzed the correlation between body mass index (BMI) and primitive site of polyps.
  
  
  METHODS
  We performed a retrospective study, in a period between January 2010 and October 2014. Subjects aged 50 years and older who underwent their first-time screening colonoscopy were included. Reports regarding characteristic of the polyps were collected.
  
  
  RESULTS
  142 patients were enrolled and they were divided into two groups: group I - patients with left sided colonic polyps, and group II - patients who right sided colonic polyps. The ANOVA test-one way, documents a difference between the BMI and the colon localization of polyps.
  
  
  CONCLUSIONS
  Patients with overweight had a higher risk to develop lesions in the left colon compared to patients with normal weight. Despite the fact that Italian epidemiological studies have found a prevalence of polyps of 44-53% in rectal-sigmoid segment, 32-36% in transverse segment and of 14-20% in right segment, we showed an incidence of 26.05% for right sided polyps, which maybe related with the eating habits of the territory.
authors.affiliation: Department of Surgery, Annunziata Hospital of Cosenza, Cosenza, Italy. Electronic address: anubis_m@libero.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Cannistrà
authors.affiliation: Department of Surgery, Annunziata Hospital of Cosenza, Cosenza, Italy. Electronic address: ruggant@alice.it.
authors.forename: Michele
authors.initials: M
authors.lastname: Ruggiero
authors.affiliation: Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: raffaele.eia@alice.it.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Grande
authors.affiliation: Service of Endoscopic Surgery, Unit of Emergency Surgery, Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: emaluele.sireno@gmail.com.
authors.forename: Emanuele
authors.initials: E
authors.lastname: Sireno
authors.affiliation: Service of Endoscopic Surgery, Unit of Emergency Surgery, Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: rino.colace@alice.it.
authors.forename: Rosario
authors.initials: R
authors.lastname: Colace
authors.affiliation: Service of Endoscopic Surgery, Unit of Emergency Surgery, Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: riccardocalabria@libero.it.
authors.forename: Riccardo Domenico Ferdinando
authors.initials: RD
authors.lastname: Calabria
authors.affiliation: Service of Endoscopic Surgery, Unit of Emergency Surgery, Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: alberico.guido@libero.it.
authors.forename: Alberico
authors.initials: A
authors.lastname: Guido
authors.affiliation: Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: arizzuto@unicz.it.
authors.forename: Antonia
authors.initials: A
authors.lastname: Rizzuto
authors.affiliation: Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: sacco@unicz.it.
authors.forename: Rosario
authors.initials: R
authors.lastname: Sacco
authors.affiliation: Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: rserra@unicz.it.
authors.forename: Raffaele
authors.initials: R
authors.lastname: Serra
authors.affiliation: Department of Medical and Surgical Sciences, University of Catanzaro, Italy; Service of Endoscopic Surgery, Unit of Emergency Surgery, Department of Medical and Surgical Sciences, University of Catanzaro, Italy. Electronic address: sammarco@unicz.it.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Sammarco
mesh_terms: D000236:Adenoma / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015992:Body Mass Index; D003113:Colonoscopy; D015179:Colorectal Neoplasms / Q000453:epidemiology* / Q000209:etiology / Q000473:pathology; D005260:Female; D006801:Humans; D015994:Incidence; D007558:Italy / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D050177:Overweight / Q000150:complications; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Body mass index; Colorectal cancer; Endoscopy; Polyps