title: [CHANGES OF HISTOSTRUCTURE OF CHRONIC ANAL FISSURE, DEPENDING ON DURATION OF THE DISEASE].
abstract: The results of histological investigation of the chronic anal fissure (AF) edges in 95 patients with the disease duration from 6 mo to 4.5 yrs were analyzed. Basing on estimation of severity of an acute inflammation signs and the granulation and cicatricial tissue presence there was established, that duration of an acute inflammation in the AF may constitute up to 6 - 7 mo; subacute--from 8 to 11 mo, chronic cicatricial process was observed in terms from 12 mo and more.
authors.forename: T I
authors.initials: TI
authors.lastname: Tamm
authors.forename: V V
authors.initials: VV
authors.lastname: Tsodikov
authors.forename: V V
authors.initials: VV
authors.lastname: Sedak
authors.forename: O N
authors.initials: ON
authors.lastname: Pliten
authors.forename: M S
authors.initials: MS
authors.lastname: Miroshnichenko
mesh_terms: D000328:Adult; D001003:Anal Canal / Q000473:pathology* / Q000601:surgery; D049109:Cell Proliferation; D002908:Chronic Disease; D002921:Cicatrix / Q000150:complications / Q000473:pathology* / Q000601:surgery; D004847:Epithelial Cells / Q000473:pathology; D005260:Female; D005401:Fissure in Ano / Q000150:complications / Q000473:pathology* / Q000601:surgery; D006801:Humans; D007249:Inflammation; D008297:Male; D008875:Middle Aged; D032389:Myocytes, Smooth Muscle / Q000473:pathology; D011127:Polyps / Q000150:complications / Q000473:pathology* / Q000601:surgery; D012720:Severity of Illness Index; D013997:Time Factors