title: Using 80 kVp on a 320-row scanner for hepatic multiphasic CT reduces the contrast dose by 50 % in patients at risk for contrast-induced nephropathy.
abstract: OBJECTIVE
  We evaluated the effects of a low contrast material (CM) dose protocol using 80-kVp on the image quality of hepatic multiphasic CT scans acquired on a 320-row CT scanner.
  
  
  METHODS
  We scanned 30 patients with renal insufficiency (eGFR < 45 mL/min/1.73 m2) using 80-kVp and a CM dose of 300mgI/kg. Another 30 patients without renal insufficiency (eGFR > 60 mL/min/1.73 m2) were scanned with the conventional 120-kVp protocol and the standard CM dose of 600mgI/kg. Quantitative image quality parameters, i.e. CT attenuation, image noise, and the contrast-to-noise ratio (CNR) were compared and the visual image quality was scored on a four-point scale. The volume CT dose index (CTDIvol) and the size-specific dose estimate (SSDE) recorded with the 80- and the 120-kVp protocols were also compared.
  
  
  RESULTS
  Image noise and contrast enhancement were equivalent for the two protocols. There was no significant difference in the CNR of all anatomic sites and in the visual scores for overall image quality. The CTDIvoland SSDE were approximately 25-30 % lower under the 80-kVp protocol.
  
  
  CONCLUSIONS
  Hepatic multiphase CT using 80-kVp on a 320-row CT scanner allowed for a decrease in the CM dose and a reduction in the radiation dose without image quality degradation in patients with renal insufficiency.
  
  
  CONCLUSIONS
  • The 80-kVp CT protocol enabled reduction of contrast dose by 50 % • The 80-kVp CT protocol reduced the radiation dose by 25-33 % • There was no degradation in the image quality of the 80-kVp protocol.
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Narumi
authors.initials: N
authors.lastname: Taguchi
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan. seisei0430@nifty.com.
authors.forename: Seitaro
authors.initials: S
authors.lastname: Oda
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Utsunomiya
authors.affiliation: Department of Medical Physics, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
authors.forename: Yoshinori
authors.initials: Y
authors.lastname: Funama
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Nakaura
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Imuta
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Sadahiro
authors.initials: S
authors.lastname: Yamamura
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Hideaki
authors.initials: H
authors.lastname: Yuki
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Masafumi
authors.initials: M
authors.lastname: Kidoh
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Kenichiro
authors.initials: K
authors.lastname: Hirata
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Namimoto
authors.affiliation: Department of Central Radiology, Kumamoto University Hospital, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Hatemura
authors.affiliation: Department of Central Radiology, Kumamoto University Hospital, 1-1-1 Honjyo, Chuo-ku, Kumamoto, 860-8556, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Kai
authors.affiliation: Department of Diagnostic Radiology, Faculty of Life Sciences, Kumamoto University, 1-1-1 Honjyo, Chuou-ku, Kumamoto, 860-8556, Japan.
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamashita
mesh_terms: D058186:Acute Kidney Injury / Q000139:chemically induced / Q000517:prevention & control*; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D003287:Contrast Media / Q000008:administration & dosage* / Q000009:adverse effects; D005260:Female; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011829:Radiation Dosage; D011856:Radiographic Image Enhancement; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods; D051437:Renal Insufficiency; D014057:Tomography, X-Ray Computed / Q000379:methods*
chemical_list: D003287:Contrast Media
keywords: 320-row CT; 80 kVp; Contrast-induced nephropathy; Hepatic multiphasic CT; Image quality