title: Balloon kyphoplasty or percutaneous vertebroplasty for osteoporotic vertebral compression fracture? An updated systematic review and meta-analysis.
abstract: BACKGROUND
  Both kyphoplasty (KP) and vertebroplasty (VP) are effective for patients with osteoporotic vertebral compression fracture (OVCF), but which approach might be more effective remains unclear, so we decided to update earlier systematic reviews.
  
  
  OBJECTIVE
  Review and analyze studies published as of August 2015 that compared clinical outcomes and complications of KP versus VP.
  
  
  METHODS
  Systematic review and meta-analysis.
  
  
  METHODS
  Published reports up to August 2015 were found in PubMed, EMBASE and the Cochrane Central Register of Controlled Trials (CENTRAL).
  
  
  METHODS
  Randomized controlled trials (RCTs) and prospective and retrospective cohort stud.ies comparing KP and VP in patients with OVCF.
  
  
  METHODS
  Two authors independently assessed the studies and extracted data.
  
  
  RESULTS
  Thirty-two studies involving 3274 patients fulfilled the inclusion criteria. There were significant differences between the two groups in short- and long-term postoperative changes in measures of pain intensity and dysfunction (P < .01), in anterior and middle height (P < .01), kyphotic angle (P < .01), and time to injury, but not in posterior height (P=.178). There were no significant differences in the rate of postoperative fractures including adjacent and total fractures, but cement leakage to the intraspinal space was greater in the VP group (P=.035). KP surgery took longer and required a greater volume of injected cement.
  
  
  CONCLUSIONS
  KR resulted in better pain relief, improvements in Oswestry dysfunction and radiographic outcomes with less cement leakage, but further RCTs are needed to verify this conclusion.
  
  
  CONCLUSIONS
  Only four RCTs with a certain of risk of bias. Most studies were observational.
authors.forename: Lin
authors.initials: L
authors.lastname: Liang
authors.forename: Xinlei
authors.initials: X
authors.lastname: Chen
authors.forename: Weimin
authors.initials: W
authors.lastname: Jiang
authors.forename: Xuefeng
authors.initials: X
authors.lastname: Li
authors.forename: Jie
authors.initials: J
authors.lastname: Chen
authors.forename: Lijun
authors.initials: L
authors.lastname: Wu
authors.affiliation: Prof. Yangyi Zhu, Department of Orthopaedics,, Shangyu People's Hospital, University,, No. 899 Pinghai Road, Suzhou 215006, China, Shaoxing 312000, China, F: 86057581266120, boss2014jaing@163.com, ORCID ID: orcid.org/0000-0002-2654-8360.
authors.forename: Yangyi
authors.initials: Y
authors.lastname: Zhu
mesh_terms: D001843:Bone Cements / Q000009:adverse effects; D004185:Disability Evaluation; D050815:Fractures, Compression / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty / Q000009:adverse effects / Q000379:methods*; D061646:Operative Time; D058866:Osteoporotic Fractures / Q000601:surgery*; D010147:Pain Measurement; D016103:Spinal Fractures / Q000601:surgery*; D016896:Treatment Outcome; D054854:Vertebroplasty / Q000009:adverse effects / Q000379:methods*
chemical_list: D001843:Bone Cements