title: Advanced Genetic Methodologies in Tracking Evolution and Spread of Chikungunya Virus.
abstract: Recent advances in genetic methodologies have substantially expanded our ability to track evolution and spatio-temporal distribution of rapidly evolving pathogens. The information gathered from such analyses can be used to decipher host adaptations that shape disease epidemiology. In this chapter, we demonstrate the utilization of freely available resources to track the evolution and spread of Chikungunya virus.
authors.affiliation: Environmental Health Institute, National Environment Agency, 11, BioPolis Way, Helios #06-05/08, Singapore, 138667, Singapore. chanditha_hapuarachchi@nea.gov.sg.
authors.forename: Hapuarachchige Chanditha
authors.initials: HC
authors.lastname: Hapuarachchi
authors.affiliation: School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, Block 83, #04-00, 535 Clementi Road, Singapore, 599489, Singapore. lks9@np.edu.sg.
authors.forename: Kim-Sung
authors.initials: KS
authors.lastname: Lee
mesh_terms: D002646:Chikungunya virus / Q000145:classification* / Q000235:genetics*; D019143:Evolution, Molecular; D059645:Mutation Rate; D010802:Phylogeny; D058974:Phylogeography; D020641:Polymorphism, Single Nucleotide; D012367:RNA, Viral / Q000235:genetics*
chemical_list: D012367:RNA, Viral
keywords: Chikungunya virus; Common ancestor; Evolution; Evolutionary network; Multiple alignment; Phylogenetics; Phylogeography