title: A dual-mode turn-on fluorescent BODIPY-based probe for visualization of mercury ions in living cells.
abstract: A novel turn-on fluorescent 8-amino BODIPY-based probe carrying a thiourea unit as the mercury ion recognition unit has been developed. Due to the cascade reaction processes, consecutive color changes reflecting the electronic absorption and emission responses were observed upon addition of increased concentrations of mercury(ii) ions. The likely sensing mechanism was proposed as mercury ion-promoted cyclization and subsequent hydrolysis. The probe displayed a selective response to mercury ions over other metal ions. Additionally, experiments with living Human Hepatoma SMMC-7721 cells to visualize intracellular mercury ions in biological systems were carried out with the probe.
authors.affiliation: Key Laboratory for Special Functional Materials of the Ministry of Education, Henan University, Kaifeng, 475004, P. R. China. zwjuan1965@henu.edu.cn zhaow@henu.edu.cn.
authors.forename: Yue
authors.initials: Y
authors.lastname: Wang
authors.forename: Fuchao
authors.initials: F
authors.lastname: Pan
authors.forename: Yuanlin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Fangfang
authors.initials: F
authors.lastname: Peng
authors.forename: Zhentao
authors.initials: Z
authors.lastname: Huang
authors.forename: Weijuan
authors.initials: W
authors.lastname: Zhang
authors.forename: Weili
authors.initials: W
authors.lastname: Zhao
mesh_terms: D001896:Boron Compounds; D045744:Cell Line, Tumor; D005456:Fluorescent Dyes; D006801:Humans; D007477:Ions; D008628:Mercury / Q000032:analysis*; D013050:Spectrometry, Fluorescence
chemical_list: C095489:4,4-difluoro-4-bora-3a,4a-diaza-s-indacene; D001896:Boron Compounds; D005456:Fluorescent Dyes; D007477:Ions; D008628:Mercury