title: Organizing pneumonia as the first manifestation of anti-synthetase syndrome.
abstract: BACKGROUND
  Anti-synthetase syndrome associated interstitial lung disease can occur either simultaneously, before, or after the development of polymyositis/dermatomyositis. Histology of interstitial lung disease can be nonspecific interstitial pneumonia, usual interstitial pneumonia, diffuse alveolar damage, organizing pneumonia. Organizing pneumonia associated anti-synthetase syndrome is a rare finding especially as the first manifestation.
  
  
  METHODS
  We report a 41 year old male patient who presented with organizing pneumonia and 2 years following the onset, developed polymyositis with anti-JO-1 antibody positivity.
  
  
  CONCLUSIONS
  It is important to screen patients with organizing pneumonia for anti-synthetase syndrome which can be manifested later.
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka. thanujatissera@gmail.com.
authors.forename: S M Thanuja Nilushi
authors.initials: SM
authors.lastname: Priyangika
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka.
authors.forename: W G S G
authors.initials: WG
authors.lastname: Karunarathna
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka.
authors.forename: Isurujith
authors.initials: I
authors.lastname: Liyanage
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka.
authors.forename: Methsala
authors.initials: M
authors.lastname: Gunawardana
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka.
authors.forename: Sumeda
authors.initials: S
authors.lastname: Udumalgala
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka.
authors.forename: Chamith
authors.initials: C
authors.lastname: Rosa
authors.affiliation: National hospital of Sri Lanka, Colombo, Sri Lanka.
authors.forename: Aruna
authors.initials: A
authors.lastname: Kulatunga
mesh_terms: D000328:Adult; D000974:Antibodies, Antinuclear / Q000276:immunology*; D018549:Cryptogenic Organizing Pneumonia / Q000150:complications / Q000175:diagnosis* / Q000276:immunology; D003882:Dermatomyositis / Q000150:complications / Q000276:immunology; D006643:Histidine-tRNA Ligase / Q000276:immunology*; D006801:Humans; D017563:Lung Diseases, Interstitial / Q000150:complications / Q000276:immunology; D008297:Male; D013577:Syndrome
chemical_list: D000974:Antibodies, Antinuclear; C046750:Jo-1 antibody; D006643:Histidine-tRNA Ligase
keywords: Anti-JO-1 antibody; Anti-synthetase syndrome; Interstitial lung disease; Organizing pneumonia; Polymyositis