title: Utility of colon leakage score in left-sided colorectal surgery.
abstract: The aim of the study was to evaluate the clinical utility of the colon leakage score (CLS) in predicting the risk of anastomotic leakage (AL) after left-sided colorectal surgery.
  
  
  
  This investigation was designed as a retrospective study of 304 patients who underwent left-sided colorectal surgery. The patients were classified into two groups as those who developed AL and those who did not develop AL, and the CLSs of the two groups were compared. The predictive value and the cutoff value of the CLS were assessed by receiver operating characteristic and logistic regression analysis.
  
  
  
  A significant difference was noted in the mean CLSs of the groups with and without AL (P < 0.001). The values of the area under the receiver operating characteristic curve (0.965; confidence interval, 0.913-1.00) and the odds ratio (2.9; confidence interval, 1.59-4.83; P < 0.001) indicated that CLS was a good predictor of AL. A CLS of 11 was found to be the best cutoff value, with a sensitivity and specificity of 84.6% and 87.2%, respectively.
  
  
  
  Our findings indicate that CLS can effectively predict the risk of AL after left-sided colorectal surgery and that a CLS of 11 can be used as a cutoff value for the risk level.
authors.affiliation: Department of Colorectal Surgery, Clinical Center of Intestinal and Colorectal Diseases of Hubei Province, Key Laboratory of Intestinal and Colorectal Diseases of Hubei Province, Zhongnan Hospital of Wuhan University, Wuhan, China. Electronic address: yuxueqiao2008@163.com.
authors.forename: Xue-Qiao
authors.initials: XQ
authors.lastname: Yu
authors.affiliation: Department of General Surgery, Beijing Chaoyang Hospital, Beijing, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Zhao
authors.affiliation: Department of Gastrointestinal Surgery, Hainan General Hospital, Haikou, China.
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Zhou
authors.affiliation: Department of Medical Records and Statistics, Hainan General Hospital, Haikou, China.
authors.forename: Li-Zhen
authors.initials: LZ
authors.lastname: Han
authors.affiliation: Department of Gastrointestinal Surgery, Hainan General Hospital, Haikou, China.
authors.forename: Guo-Hao
authors.initials: GH
authors.lastname: Cai
authors.affiliation: Department of Gastrointestinal Surgery, Hainan General Hospital, Haikou, China.
authors.forename: Zhuang-Wei
authors.initials: ZW
authors.lastname: Fang
authors.affiliation: Department of Gastrointestinal Surgery, Hainan General Hospital, Haikou, China.
authors.forename: Yong-Hong
authors.initials: YH
authors.lastname: Peng
authors.affiliation: Department of Gastrointestinal Surgery, Hainan General Hospital, Haikou, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Yuan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D057868:Anastomotic Leak / Q000175:diagnosis* / Q000209:etiology / Q000517:prevention & control; D016022:Case-Control Studies; D003082:Colectomy; D003106:Colon / Q000601:surgery*; D003661:Decision Support Techniques; D005260:Female; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D012372:ROC Curve; D012007:Rectum / Q000601:surgery*; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D012680:Sensitivity and Specificity
keywords: Anastomotic leakage; Colon cancer; Colon leakage score; Left-sided colorectal surgery; Risk