title: A prospective interventional study of effect of accelerated orthokeratology on the corneal curvature and refraction among young adults with myopia.
abstract: BACKGROUND
  Orthokeratology with reverse geometry contact lens is a non-surgical alternative to conventional contact lenses for correction of myopia. However, the strength of evidence for its efficacy and safety is limited to retrospective studies and only a few prospective studies. This prospective study, the first on Indian subjects, evaluated the outcome of orthokeratology among young myopes.
  
  
  METHODS
  Fifty eyes of 25 young myopes (age 19-29 years) with myopia of -1 to 5.0 diopter underwent accelerated orthokeratology using the reverse geometry ortho K - LK lenses for correction of myopia. They were followed up prospectively with weekly vision, refraction, corneal topography, and pachymetry to assess the correction of myopia.
  
  
  RESULTS
  The mean Log MAR vision corrected from 0.748 ± 0.225 at base line to 0.025 ± 0.0630 at 12 weeks with 86% achieving 6/6 unaided day time vision. This was associated with significant central corneal flattening and thinning. The lenses were well tolerated with no significant complications.
  
  
  CONCLUSIONS
  Overnight accelerated orthokeratology effectively corrects moderate degree of myopia and provide excellent spectacle free day time vision without any significant adverse effects in the short term.
authors.affiliation: Associate Professor, Dept of Ophthalmology, Armed Forces Medical College, Pune 411040, India.
authors.forename: M A
authors.initials: MA
authors.lastname: Khan
authors.affiliation: Resident, Dept of Ophthalmology, Armed Forces Medical College, Pune 411040, India.
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Commandant, Command Hospital (Eastern Command), Kolkata, India.
authors.forename: T S
authors.initials: TS
authors.lastname: Ahluwalia
authors.affiliation: Professor and Head, Dept of Ophthalmology, Armed Forces Medical College, Pune 411040, India.
authors.forename: P S
authors.initials: PS
authors.lastname: Moulick
authors.affiliation: Commandant, Military Hospital Wellington, Tamil Nadu, India.
authors.forename: V S
authors.initials: VS
authors.lastname: Gurunadh
authors.affiliation: Assistant Professor, Dept of Ophthalmology, Armed Forces Medical College, Pune 411040, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Gupta
keywords: Contact lens; Myopia; Orthokeratology