title: Treatment of nodular vasculitis with colchicine.
abstract: Nodular vasculitis (NV) refers to a chronic relapsing lobular panniculitis that is thought to be a hypersensitivity reaction to antigenic triggers. While it is commonly associated with tuberculosis, in many cases no underlying cause is found and the condition is difficult to manage. Here, we report three patients with refractory idiopathic NV effectively treated with colchicine, leading to a significant improvement or complete resolution of their symptoms. Colchicine was successfully used as a steroid-sparing agent, and in one patient its cessation was associated with a flare of disease.
authors.affiliation: Department of Dermatology, St Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: Edmund
authors.initials: E
authors.lastname: Wee
authors.affiliation: Department of Dermatology, St Vincent's Hospital, Melbourne, Victoria, Australia.
authors.forename: Robert I
authors.initials: RI
authors.lastname: Kelly
mesh_terms: D000328:Adult; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D003078:Colchicine / Q000627:therapeutic use*; D004891:Erythema Induratum / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008875:Middle Aged; D011239:Prednisolone / Q000627:therapeutic use; D000067251:Symptom Flare Up; D050257:Tubulin Modulators / Q000627:therapeutic use*
chemical_list: D000893:Anti-Inflammatory Agents; D050257:Tubulin Modulators; D011239:Prednisolone; D003078:Colchicine
keywords: colchicine; erythema induratum; nodular vasculitis; panniculitis