title: [Perioperative management of transthoracic oesophagectomies : Fundamentals of interdisciplinary care and new approaches to accelerated recovery after surgery].
abstract: Locally advanced carcinomas of the oesophagus require multimodal treatment. The core element of curative therapy is transthoracic en bloc oesophagectomy, which is the standard procedure carried out in most specialized centres. Reconstruction of intestinal continuity is usually achieved with a gastric sleeve, which is anastomosed either intrathoracically or cervically to the remaining oesophagus. This thoraco-abdominal operation is associated with significant postoperative morbidity, not least because of a vast array of pre-existing illnesses in the surgical patient. For an optimal outcome, the careful interdisciplinary selection of patients, preoperative risk evaluation and conditioning are essential. The caseload of the centres correlates inversely with the complication rate. The leading surgical complication is anastomotic leakage, which is diagnosed endoscopically and usually treated with the aid of endoscopic procedures. Pulmonary infections are the most frequent non-surgical complication. Thoracic epidural anaesthesia and perfusion-orientated fluid management can reduce the rate of pulmonary complications. Patients are ventilated protecting the lungs and are extubated as early as possible. Oesophagectomies should only be performed in high-volume centres with the close cooperation of surgeons and anaesthesia/intensive care specialists. Programmes of enhanced recovery after surgery (ERAS) hold further potential for the patient's quicker postoperative recovery. In this review article the fundamental aspects of the interdisciplinary perioperative management of transthoracic oesophagectomy are described.
authors.affiliation: Klinik für Allgemein-, Viszeral- und Tumorchirurgie, Uniklinik Köln, Köln, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Lambertz
authors.affiliation: Klinik für Anästhesiologie und Operative Intensivmedizin, Uniklinik Köln, Kerpenerstr. 62, 50937, Köln, Deutschland.
authors.forename: H
authors.initials: H
authors.lastname: Drinhaus
authors.affiliation: Klinik für Anästhesiologie und Operative Intensivmedizin, Uniklinik Köln, Kerpenerstr. 62, 50937, Köln, Deutschland.
authors.forename: D
authors.initials: D
authors.lastname: Schedler
authors.affiliation: Klinik für Allgemein-, Viszeral- und Tumorchirurgie, Uniklinik Köln, Köln, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Bludau
authors.affiliation: Klinik für Allgemein-, Viszeral- und Tumorchirurgie, Uniklinik Köln, Köln, Deutschland.
authors.forename: W
authors.initials: W
authors.lastname: Schröder
authors.affiliation: Klinik für Anästhesiologie und Operative Intensivmedizin, Uniklinik Köln, Kerpenerstr. 62, 50937, Köln, Deutschland. thorsten.annecke@uk-koeln.de.
authors.forename: T
authors.initials: T
authors.lastname: Annecke
mesh_terms: D000758:Anesthesia; D000762:Anesthesia Recovery Period; D003131:Combined Modality Therapy; D004938:Esophageal Neoplasms / Q000601:surgery; D016629:Esophagectomy / Q000379:methods*; D006801:Humans; D010348:Patient Care Team; D019990:Perioperative Care / Q000379:methods*; D019616:Thoracic Surgical Procedures / Q000379:methods*
keywords: Anesthesiology; Oesophageal Neoplasms; Oesophagectomy; Perioperative Risk; Surgery