title: [A case of palmoplantar dysesthesia syndrome caused by capecitabine].
abstract: Palmoplantar dysesthesia is a dermatologic toxic reaction caused by chemotherapeutics. Also known as hand-foot syndrome, it is not life-threatening, but does decrease quality of life. Dysesthesia, erythema, edema, and desquamation on palmoplantar region are observed clinically. Palmoplantar dysesthesia syndrome may be caused by chemotherapeutics including cytarabine, doxorubicin, capecitabine, epirubicin, docetaxel, vinorelbine, and 5-fluorouracil. The case of a 62-year-old woman who presented with diffuse erythema on palmoplantar area after use of capecitabine for metastatic breast carcinoma is described in the present report. Palmoplantar dysesthesia syndrome caused by capecitabine may affect patient compliance.
authors.affiliation: Department of Dermatology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Ömer Faruk
authors.initials: ÖF
authors.lastname: Elmas
authors.affiliation: Department of Dermatology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Mahmut Sami
authors.initials: MS
authors.lastname: Metin
authors.affiliation: Department of Dermatology, Ataturk University Faculty of Medicine, Erzurum, Turkey. erester.34@hotmail.com.
authors.forename: Okan
authors.initials: O
authors.lastname: Kızılyel
authors.affiliation: Department of Internal Medicine, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Akın
authors.initials: A
authors.lastname: Aktaş
authors.affiliation: Department of Dermatology, Ataturk University Faculty of Medicine, Erzurum, Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Birdal
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000009:adverse effects*; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000009:adverse effects; D001943:Breast Neoplasms / Q000188:drug therapy; D000069287:Capecitabine / Q000009:adverse effects*; D003937:Diagnosis, Differential; D005260:Female; D005533:Foot Dermatoses / Q000139:chemically induced / Q000175:diagnosis*; D006229:Hand Dermatoses / Q000139:chemically induced / Q000175:diagnosis*; D006801:Humans; D008875:Middle Aged; D013577:Syndrome
chemical_list: D000964:Antimetabolites, Antineoplastic; D000069287:Capecitabine