title: [Nonsurgical management of mild primary hyperparathyroidism].
abstract: Primary hyperparathyroidism (PHPT) is one of the common endocrine disorders, which results clinically in nephrolithiasis, osteoporosis, muscle weakness, cardiac and psychiatric abnormalities even in a mild or asymptomatic disease. Parathyroidectomy (PTX) is the only definitive treatment for PHPT, however, some patients with sporadic PHPT refuse surgery, are medically unfit, or have residual or recurrent disease inaccessible to further surgery. These patients may require intervention for management of symptomatic or moderate to severe hypercalcemia, bone loss or kidney calculi.
authors.affiliation: Department of Metabolism, Endocrinology and Molecular Medicine,Osaka City University Graduate School of Medicine, Japan.
authors.forename: Yasuo
authors.initials: Y
authors.lastname: Imanishi
mesh_terms: D015519:Bone Density; D006801:Humans; D049950:Hyperparathyroidism, Primary / Q000188:drug therapy* / Q000378:metabolism; D010281:Parathyroid Hormone / Q000378:metabolism; D016105:Parathyroidectomy; D044169:Receptors, Calcium-Sensing / Q000378:metabolism; D013964:Thyroid Neoplasms / Q000188:drug therapy
chemical_list: D010281:Parathyroid Hormone; D044169:Receptors, Calcium-Sensing