title: Reducing Overtreatment in Gynecologic Oncology: The Case for Less in Endometrial and Ovarian Cancer.
abstract: A growing awareness of the harms of overtreatment in cancer care has reached physicians, patients, health policy makers, and medical researchers. Overtreatment exposes patients to the risk of adverse events from procedures or medications that were not necessary. This review examines common practices in gynecologic malignancies that are unlikely to produce direct benefit to patients with these malignancies, but are likely to produce harms. Specifically, we will explore the utility of lymphadenectomy and adjuvant radiation for women with early-stage endometrial cancer; and screening for recurrence and continuous chemotherapy for advanced-stage ovarian cancer patients.
authors.affiliation: The Division of Cancer Prevention, The National Cancer Institute, National Institutes of Health , Bethesda, MD , USA.
authors.forename: Sarah M
authors.initials: SM
authors.lastname: Temkin
authors.affiliation: The Kelly Gynecologic Oncology Service, Johns Hopkins School of Medicine , Baltimore, MD , USA.
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Tanner
authors.affiliation: Division of Gynecologic Oncology, Rush University School of Medicine , Chicago, IL , USA.
authors.forename: Summer B
authors.initials: SB
authors.lastname: Dewdney
authors.affiliation: The Division of Cancer Prevention, The National Cancer Institute, National Institutes of Health , Bethesda, MD , USA.
authors.forename: Lori M
authors.initials: LM
authors.lastname: Minasian
keywords: cancer care delivery; endometrial cancer; gynecologic cancer; ovarian cancer; overtreatment