title: The wheat Sr50 gene reveals rich diversity at a cereal disease resistance locus.
abstract: We identify the wheat stem rust resistance gene Sr50 (using physical mapping, mutation and complementation) as homologous to barley Mla, encoding a coiled-coil nucleotide-binding leucine-rich repeat (CC-NB-LRR) protein. We show that Sr50 confers a unique resistance specificity different from Sr31 and other genes on rye chromosome 1RS, and is effective against the broadly virulent Ug99 race lineage. Extensive haplotype diversity at the rye Sr50 locus holds promise for mining effective resistance genes.
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Rohit
authors.initials: R
authors.lastname: Mago
authors.affiliation: Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia.
authors.forename: Peng
authors.initials: P
authors.lastname: Zhang
authors.affiliation: INRA - CNRGV, 24 Chemin de Borde Rouge - Auzeville, CS 52627, Castanet Tolosan Cedex 31326, France.
authors.forename: Sonia
authors.initials: S
authors.lastname: Vautrin
authors.affiliation: Institute of Experimental Botany, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, Olomouc CZ-78371, Czech Republic.
authors.forename: Hana
authors.initials: H
authors.lastname: Šimková
authors.affiliation: Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia.
authors.forename: Urmil
authors.initials: U
authors.lastname: Bansal
authors.affiliation: Department of Plant Sciences, University of California, Davis, California 95616, USA.
authors.forename: Ming-Cheng
authors.initials: MC
authors.lastname: Luo
authors.affiliation: USDA, ARS Cereal Disease Laboratory, University of Minnesota, Saint Paul, Minnesota 55108, USA.
authors.forename: Matthew
authors.initials: M
authors.lastname: Rouse
authors.affiliation: Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia.
authors.forename: Haydar
authors.initials: H
authors.lastname: Karaoglu
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Sambasivam
authors.initials: S
authors.lastname: Periyannan
authors.affiliation: USDA, ARS Cereal Disease Laboratory, University of Minnesota, Saint Paul, Minnesota 55108, USA.
authors.forename: James
authors.initials: J
authors.lastname: Kolmer
authors.affiliation: USDA, ARS Cereal Disease Laboratory, University of Minnesota, Saint Paul, Minnesota 55108, USA.
authors.forename: Yue
authors.initials: Y
authors.lastname: Jin
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Michael A
authors.initials: MA
authors.lastname: Ayliffe
authors.affiliation: Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia.
authors.forename: Harbans
authors.initials: H
authors.lastname: Bariana
authors.affiliation: Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia.
authors.forename: Robert F
authors.initials: RF
authors.lastname: Park
authors.affiliation: Plant Breeding Institute, The University of Sydney, Private Bag 4011, Narellan, New South Wales 2567, Australia.
authors.forename: Robert
authors.initials: R
authors.lastname: McIntosh
authors.affiliation: Institute of Experimental Botany, Centre of the Region Haná for Biotechnological and Agricultural Research, Šlechtitelů 31, Olomouc CZ-78371, Czech Republic.
authors.forename: Jaroslav
authors.initials: J
authors.lastname: Doležel
authors.affiliation: INRA - CNRGV, 24 Chemin de Borde Rouge - Auzeville, CS 52627, Castanet Tolosan Cedex 31326, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Bergès
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Spielmeyer
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Evans S
authors.initials: ES
authors.lastname: Lagudah
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Jeff G
authors.initials: JG
authors.lastname: Ellis
authors.affiliation: CSIRO Agriculture, GPO Box 1600, Canberra ACT 2601, Australia.
authors.forename: Peter N
authors.initials: PN
authors.lastname: Dodds