title: Preclinical metrics to predict through-focus visual acuity for pseudophakic patients.
abstract: This study compares the clinical through-focus visual acuity (VA) in patients implanted with different intraocular lens (IOL) to optical bench testing of the same IOLs to evaluate the suitability of optical metrics of predicting clinical VA. Modulation transfer function and phase transfer function for different spatial frequencies and US Air Force pictures were measured using an optical bench for two monofocal IOLs, three multifocal IOLs and an extended range of vision IOL. Four preclinical metrics were calculated and compared to the clinical through-focus VA collected in three different clinical studies (243 patients in total). All metrics were well correlated (R(2)≥0.89) with clinical data and may be suitable for predicting through-focus VA in pseudophakic eyes.
authors.affiliation: AMO Groningen, van Swietenlaan, Groningen, 9728 NX, The Netherlands.
authors.forename: Aixa
authors.initials: A
authors.lastname: Alarcon
authors.affiliation: AMO Groningen, van Swietenlaan, Groningen, 9728 NX, The Netherlands.
authors.forename: Carmen
authors.initials: C
authors.lastname: Canovas
authors.affiliation: AMO Groningen, van Swietenlaan, Groningen, 9728 NX, The Netherlands.
authors.forename: Robert
authors.initials: R
authors.lastname: Rosen
authors.affiliation: AMO Groningen, van Swietenlaan, Groningen, 9728 NX, The Netherlands.
authors.forename: Henk
authors.initials: H
authors.lastname: Weeber
authors.affiliation: AMO Santa Ana, CA, 1700 East St. Andrew Place Santa Ana, CA 92705, USA.
authors.forename: Linda
authors.initials: L
authors.lastname: Tsai
authors.affiliation: AMO Santa Ana, CA, 1700 East St. Andrew Place Santa Ana, CA 92705, USA.
authors.forename: Kendra
authors.initials: K
authors.lastname: Hileman
authors.affiliation: AMO Groningen, van Swietenlaan, Groningen, 9728 NX, The Netherlands.
authors.forename: Patricia
authors.initials: P
authors.lastname: Piers
keywords: (170.4470) Ophthalmology; (330.1070) Vision - acuity; (330.4460) Ophthalmic optics and devices; (330.5370) Physiological optics; (330.7326) Visual optics, modeling; (330.7335) Visual optics, refractive surgery