title: A Highly Selective Fluorescence Turn-On Sensor for Extracellular Calcium Ion Detection.
abstract: A highly water-soluble, fluorescence turn-on sensor for Ca(2+) is reported. The sensor affords high selectivity in sensing Ca(2+) over other biologically important metal cations. The dissociation constant of the sensor in binding Ca(2+) is 0.92 mm. Fluorescence microscopy experiments demonstrate that the sensor is cell-impermeable and capable of detecting extracellular Ca(2+) .
authors.affiliation: College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey, 07102, United States.
authors.forename: Binglin
authors.initials: B
authors.lastname: Sui
authors.affiliation: College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey, 07102, United States.
authors.forename: Xinglei
authors.initials: X
authors.lastname: Liu
authors.affiliation: Department of Chemistry, University of Central Florida, Orlando, Florida, 32816, United States.
authors.forename: Mengyuan
authors.initials: M
authors.lastname: Wang
authors.affiliation: College of Science and Liberal Arts, New Jersey Institute of Technology, Newark, New Jersey, 07102, United States. belfield@njit.edu.
authors.forename: Kevin D
authors.identifier: http://orcid.org/0000-0002-7339-2813
authors.initials: KD
authors.lastname: Belfield
keywords: calcium; cell imaging; extracellular calcium detection; fluorescence microscopy; fluorescence sensors