title: High-resolution T2-weighted cervical cancer imaging: a feasibility study on ultra-high-field 7.0-T MRI with an endorectal monopole antenna.
abstract: OBJECTIVE
  We studied the feasibility of high-resolution T2-weighted cervical cancer imaging on an ultra-high-field 7.0-T magnetic resonance imaging (MRI) system using an endorectal antenna of 4.7-mm thickness.
  
  
  METHODS
  A feasibility study on 20 stage IB1-IIB cervical cancer patients was conducted. All underwent pre-treatment 1.5-T MRI. At 7.0-T MRI, an external transmit/receive array with seven dipole antennae and a single endorectal monopole receive antenna were used. Discomfort levels were assessed. Following individualised phase-based B1+shimming, T2-weighted turbo spin echo sequences were completed.
  
  
  RESULTS
  Patients had stage IB1 (n = 9), IB2 (n = 4), IIA1 (n = 1) or IIB (n = 6) cervical cancer. Discomfort (ten-point scale) was minimal at placement and removal of the endorectal antenna with a median score of 1 (range, 0-5) and 0 (range, 0-2) respectively. Its use did not result in adverse events or pre-term session discontinuation. To demonstrate feasibility, T2-weighted acquisitions from 7.0-T MRI are presented in comparison to 1.5-T MRI. Artefacts on 7.0-T MRI were due to motion, locally destructive B1interference, excessive B1under the external antennae and SENSE reconstruction.
  
  
  CONCLUSIONS
  High-resolution T2-weighted 7.0-T MRI of stage IB1-IIB cervical cancer is feasible. The addition of an endorectal antenna is well tolerated by patients.
  
  
  CONCLUSIONS
  • High resolution T2-weighted 7.0-T MRI of the inner female pelvis is challenging • We demonstrate a feasible approach for T2-weighted 7.0-T MRI of cervical cancer • An endorectal monopole receive antenna is well tolerated by participants • The endorectal antenna did not lead to adverse events or session discontinuation.
authors.affiliation: Department of Gynaecological Oncology, UMC Utrecht Cancer Centre, University Medical Centre Utrecht, PO Box 85500, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands. j.hoogendam@umcutrecht.nl.
authors.forename: Jacob P
authors.initials: JP
authors.lastname: Hoogendam
authors.affiliation: Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
authors.forename: Irene M L
authors.initials: IM
authors.lastname: Kalleveen
authors.affiliation: Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
authors.forename: Catalina S Arteaga
authors.initials: CS
authors.lastname: de Castro
authors.affiliation: Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
authors.forename: Alexander J E
authors.initials: AJ
authors.lastname: Raaijmakers
authors.affiliation: Department of Gynaecological Oncology, UMC Utrecht Cancer Centre, University Medical Centre Utrecht, PO Box 85500, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
authors.forename: René H M
authors.initials: RH
authors.lastname: Verheijen
authors.affiliation: Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
authors.forename: Maurice A A J
authors.initials: MA
authors.lastname: van den Bosch
authors.affiliation: Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
authors.forename: Dennis W J
authors.initials: DW
authors.lastname: Klomp
authors.affiliation: Department of Gynaecological Oncology, UMC Utrecht Cancer Centre, University Medical Centre Utrecht, PO Box 85500, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands.
authors.forename: Ronald P
authors.initials: RP
authors.lastname: Zweemer
authors.affiliation: Department of Radiology, University Medical Centre Utrecht, Heidelberglaan 100, Utrecht, The Netherlands.
authors.forename: Wouter B
authors.initials: WB
authors.lastname: Veldhuis
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016477:Artifacts; D002584:Cervix Uteri / Q000000981:diagnostic imaging / Q000473:pathology; D015331:Cohort Studies; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D053783:Magnetic Resonance Imaging, Interventional / Q000295:instrumentation* / Q000379:methods*; D008875:Middle Aged; D009367:Neoplasm Staging; D011446:Prospective Studies; D012007:Rectum; D012680:Sensitivity and Specificity; D002583:Uterine Cervical Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology
keywords: Antenna; Feasibility studies; Magnetic resonance imaging; Neoplasm staging; Uterine cervical neoplasms