title: Several cases of undesirable effects caused by methacrylate ultraviolet-curing nail polish for non-professional use.
abstract: BACKGROUND
  Ultraviolet (UV)-curing nail polishes based on acrylates or methacrylates are currently also available for non-professional use. The Swedish Medical Products Agency recently prohibited one brand of UV-curing polish, because several consumers reported undesirable effects after using it.
  
  
  OBJECTIVE
  To investigate whether consumers with undesirable effects after using the UV-curing nail polish that was later prohibited were contact allergic to the polish and its individual ingredients.
  
  
  METHODS
  Eight patients who had reported severe skin reactions after the use of the UV-curing polish were patch tested with two coatings of the nail polish and its ingredients at five dermatology departments in Sweden.
  
  
  RESULTS
  All patients tested except one showed contact allergic reactions to one or several of the acrylate-based or methacrylate-based ingredients in the nail polish.
  
  
  CONCLUSIONS
  The non-professional use of UV-curing nail polishes poses a risk of sensitization from acrylates and methacrylates.
authors.affiliation: Department of Occupational and Environmental Dermatology, Skåne University Hospital, 205 02, Malmö, Sweden.
authors.forename: Jakob
authors.initials: J
authors.lastname: Dahlin
authors.affiliation: Department of Medical Sciences, Dermatology and Venereology, Uppsala University, 751 85, Uppsala, Sweden.|Department of Cosmetics, Medical Products Agency, 751 03, Uppsala, Sweden.
authors.forename: Berit
authors.initials: B
authors.lastname: Berne
authors.affiliation: Department of Dermatology, Blekinge Hospital, 371 85, Karlskrona, Sweden.
authors.forename: Kari
authors.initials: K
authors.lastname: Dunér
authors.affiliation: Department of Medical Sciences, Dermatology and Venereology, Uppsala University, 751 85, Uppsala, Sweden.
authors.forename: Sara
authors.initials: S
authors.lastname: Hosseiny
authors.affiliation: Unit of Occupational and Environmental Dermatology, Centre for Occupational and Environmental Medicine, SLSO, 11365, Stockholm, Sweden.
authors.forename: Mihály
authors.initials: M
authors.lastname: Matura
authors.affiliation: Hudläkarmottagningen Telegrafen, 503 30, Borås, Sweden.
authors.forename: Gunnar
authors.initials: G
authors.lastname: Nyman
authors.affiliation: Department of Cosmetics, Medical Products Agency, 751 03, Uppsala, Sweden.
authors.forename: Monica
authors.initials: M
authors.lastname: Tammela
authors.affiliation: Department of Occupational and Environmental Dermatology, Skåne University Hospital, 205 02, Malmö, Sweden.
authors.forename: Marléne
authors.initials: M
authors.lastname: Isaksson
mesh_terms: D000179:Acrylates / Q000009:adverse effects*; D000293:Adolescent; D000328:Adult; D002648:Child; D003358:Cosmetics / Q000009:adverse effects*; D017449:Dermatitis, Allergic Contact / Q000209:etiology*; D005260:Female; D006229:Hand Dermatoses / Q000209:etiology*; D006801:Humans; D008689:Methacrylates / Q000009:adverse effects*; D009262:Nails; D010328:Patch Tests; D055815:Young Adult
chemical_list: D000179:Acrylates; D003358:Cosmetics; D008689:Methacrylates
keywords: 2-HEMA; UV nail polish; acrylate; contact allergy; methacrylate; undesirable effect