title: [Autoimmune pancreatitis as an element of autoimmune polyglandular syndrome].
abstract: Autoimmune pancreatitis constantly belongs to diseases which often causes significant diagnostic problem and often runs out with surgical intervention as considered to be a pancreatic cancer. Important although usually underestimated problems are polyglandular syndromes, which may consist of autoimmune pancreatitis (AIP) problem as well. This case report is an example of autoimmune polyglandular syndrome (APS), which was connected with the surgical treatment with biliary bypass anastomosis because of the unresectable lesion in the head of pancreas. The definite remission of the pancreatic lesion finally came after a steroid therapy. Differentiation between neoplastic and inflammatory pancreatic tumors very often remains a serious clinical problem. On grounds of imaging and cytopathology exams it is often difficult to decide about the nature of a lesion. The negative result of cytopathological biopsy examination does not finally settle straightforward diagnosis. Diagnostic problems affect also autoimmune pancreatitis. It is worth to undertake attempts to differentiate pancreatic lesions especially in cases of concomitance with other autoimmune polyglandular syndromes. That is because it is connected with completely different treatment and outcome. We should remember about diagnostic criteria of autoimmune pancreatitis. Appropriate diagnosis for patients with AIP gives them a chance to avoid serious surgical resection and possible complications.
authors.affiliation: Department of Gastroenterology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine in Warsaw, Poland.
authors.forename: Przemysław
authors.initials: P
authors.lastname: Dyrla
authors.affiliation: Department of Gastroenterology,7 Navy Hospital in Gdańsk, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Nowak
authors.affiliation: Department of Gastroenterology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine in Warsaw, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Gil
authors.affiliation: Department of Gastroenterology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine in Warsaw, Poland.
authors.forename: Cezary
authors.initials: C
authors.lastname: Adamiec
authors.affiliation: Department of Gastroenterology, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine in Warsaw, Poland.
authors.forename: Mariusz
authors.initials: M
authors.lastname: Bobula
authors.affiliation: Department of Endocrinology and Isotope Therapy, Central Clinical Hospital of the Ministry of National Defense, Military Institute of Medicine in Warsaw, Poland.
authors.forename: Marek
authors.initials: M
authors.lastname: Saracyn
mesh_terms: D000368:Aged; D001706:Biopsy; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D007074:Immunoglobulin G; D010179:Pancreas; D010190:Pancreatic Neoplasms / Q000175:diagnosis; D010195:Pancreatitis / Q000175:diagnosis*; D016884:Polyendocrinopathies, Autoimmune / Q000175:diagnosis*
chemical_list: D007074:Immunoglobulin G
keywords: IgG4-associated systemic disease (ISD); IgG4-related sclerosing disease (ISD); autoimmune pancreatitis (AIP); autoimmune polyglandular syndromes (APS); lymphoplasmacytic sclerosing pancreatitis (LPSP)