title: Acute Focal Bacterial Nephritis Associated With Central Nervous System Manifestations: A Report of 2 Cases and Review of the Literature.
abstract: Acute focal bacterial nephritis (AFBN) is a localized bacterial infection of the kidney presenting as an inflammatory mass without frank abscess formation. In children, most patients with AFBN present with nonspecific conditions, such as fever, vomiting, and abdominal pain. A small number of reported cases are accompanied by neurological symptoms, including meningeal irritation, unconsciousness, and seizures. We experienced 2 rare cases of AFBN associated with central nervous system lesions. The first case was a 3-year-old girl who had neurological symptoms, including unconsciousness and seizures, with AFBN associated with acute reversible encephalopathy. The second case was a 5-year-old girl who had neurological symptoms, including unconsciousness, with AFBN accompanied by clinically mild encephalitis/encephalopathy with a reversible splenial lesion.
authors.affiliation: From the *Department of Pediatrics and Child Health, and †Division of Medical Education Planning and Development, Nihon University School of Medicine, Tokyo, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kasuga
authors.forename: Tatsuo
authors.initials: T
authors.lastname: Fuchigami
authors.forename: Ayumi
authors.initials: A
authors.lastname: Fukuda
authors.forename: Satoko
authors.initials: S
authors.lastname: Takahashi
authors.forename: Takemi
authors.initials: T
authors.lastname: Murai
authors.forename: Ryuuta
authors.initials: R
authors.lastname: Yonezawa
authors.forename: Michio
authors.initials: M
authors.lastname: Miyashita
authors.forename: Ryutaro
authors.initials: R
authors.lastname: Kohira
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Fujita
authors.forename: Shori
authors.initials: S
authors.lastname: Takahashi
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000150:complications* / Q000188:drug therapy; D001927:Brain Diseases / Q000150:complications* / Q000188:drug therapy; D002490:Central Nervous System / Q000000981:diagnostic imaging / Q000473:pathology*; D002555:Cerebrospinal Fluid / Q000737:chemistry / Q000166:cytology; D002675:Child, Preschool; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D004660:Encephalitis / Q000150:complications*; D005260:Female; D006801:Humans; D009393:Nephritis / Q000175:diagnosis / Q000382:microbiology*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D000900:Anti-Bacterial Agents