title: Platelet-Activating Factor-Receptor and Tumor Immunity.
abstract: First described in 1972 by Benveniste and colleagues, platelet-activating factor (PAF) remains one of the potent phospholipid known to date. The role of PAF produced enzymatically in mediating diverse biological and pathophysiological processes including inflammatory and allergic diseases and cancers in response to various stimuli has been extensively studied. However, little is known about the role of non-enzymatically-generated PAF-like lipids produced in response to pro-oxidative stressors, particularly in modulating the host immune responses to tumor immunity, which is the focus of this review.
authors.affiliation: Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, USA; Department of Dermatology, Indiana University School of Medicine, USA.
authors.forename: Ravi P
authors.initials: RP
authors.lastname: Sahu
authors.affiliation: Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, USA; Department of Dermatology, Indiana University School of Medicine, USA.
authors.forename: Raymond L
authors.initials: RL
authors.lastname: Konger
authors.affiliation: Department of Pathology & Laboratory Medicine, Indiana University School of Medicine, USA; Department of Pharmacology and Toxicology, Indiana University School of Medicine, USA; Herman B. Wells Center for Pediatric Research, Indiana University School of Medicine, USA.
authors.forename: Jeffrey B
authors.initials: JB
authors.lastname: Travers