title: [Cognitive disorders in stroke patients: the possibilities of pharmacological correction].
abstract: OBJECTIVE
  To determine the efficacy and safety of cellex in treatment of cognitive disorders in acute ischemic stroke (IS).
  
  
  METHODS
  The study involved 246 patients with acute IS. Patients were randomly divided into two groups depending on the use of cellex or placebo along with basic treatment during 10 days. The dynamics of neuropsychological status was evaluated.
  
  
  CONCLUSIONS
  In IS patients, treatment with cellex have led to more rapid and marked reduction of mild and moderate cognitive disorders.
authors.affiliation: South-Ural State Medical University, Chelyabinsk, Russia.
authors.forename: G N
authors.initials: GN
authors.lastname: Belskaya
authors.affiliation: Voronez Regional Clinical Hospital #1, Voronez, Russia.
authors.forename: S E
authors.initials: SE
authors.lastname: Chuprina
authors.affiliation: Voronez Regional Clinical Hospital #1, Voronez, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Vorobyev
authors.affiliation: Voronez Regional Clinical Hospital #1, Voronez, Russia.
authors.forename: E N
authors.initials: EN
authors.lastname: Gorozha
authors.affiliation: Medical Department #1 Federal Medical Biological Agency, Novovoronez, Russia.
authors.forename: T L
authors.initials: TL
authors.lastname: Butorakina
authors.affiliation: 'Pharm-Synthesis', Moscow, Russia.
authors.forename: M A
authors.initials: MA
authors.lastname: Sokolov
authors.affiliation: 'Pharm-Synthesis', Moscow, Russia.
authors.forename: I A
authors.initials: IA
authors.lastname: Izmaylov
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003072:Cognition Disorders / Q000188:drug therapy* / Q000209:etiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D018696:Neuroprotective Agents / Q000009:adverse effects / Q000627:therapeutic use*; D009483:Neuropsychological Tests; D010455:Peptides / Q000009:adverse effects / Q000627:therapeutic use*; D020521:Stroke / Q000150:complications* / Q000503:physiopathology / Q000523:psychology; D000071939:Stroke Rehabilitation
chemical_list: D018696:Neuroprotective Agents; D010455:Peptides