title: Change in Pulse Wave Velocity and Short-Term Development of Cardiovascular Events in the Hemodialysis Population.
abstract: The association between single measurements of carotid-femoral pulse wave velocity (cfPWV) and cardiovascular (CV) events is driven by late events beyond 12 months of follow-up. This prospective study compares single measurements of cfPWV vs the 2-year delta cfPWV and the association with short-term development of CV events in hemodialysis patients. cfPWV was performed at t=0 and t=1 two years later, and patients were followed-up for development of CV events through 12 months (n=66). In Cox regression models adjusted for CV risk factors, history of CV events and delta cfPWV remained associated with the development of CV events (hazard ratio for prior CV events=8.9, P=.03; hazard ratio for delta cfPWV=1.14; P=.002). When delta cfPWV was substituted for single cfPWV measurement, none of the single measures were associated with new CV events. The change in cfPWV, but not single measurements of cfPWV, was associated with the development of CV events through 12 months.
authors.affiliation: Lebanese American University School of Medicine, Lebanon.
authors.forename: Serge
authors.initials: S
authors.lastname: Korjian
authors.affiliation: Lebanese American University School of Medicine, Lebanon.
authors.forename: Yazan
authors.identifier: 0000-0002-6364-3770
authors.initials: Y
authors.lastname: Daaboul
authors.affiliation: North Hospital Center, Zgharta, North Lebanon, Lebanon.
authors.forename: Balsam
authors.initials: B
authors.lastname: El-Ghoul
authors.affiliation: North Hospital Center, Zgharta, North Lebanon, Lebanon.
authors.forename: Salam
authors.initials: S
authors.lastname: Samad
authors.affiliation: School of Public Health, Lebanese University, Byblos-Jbeil, Lebanon.
authors.forename: Pascale
authors.initials: P
authors.lastname: Salameh
authors.affiliation: North Hospital Center, Zgharta, North Lebanon, Lebanon.
authors.forename: Georges
authors.initials: G
authors.lastname: Dahdah
authors.affiliation: Lebanese American University School of Medicine, Lebanon.
authors.forename: Essa
authors.initials: E
authors.lastname: Hariri
authors.affiliation: Lebanese American University School of Medicine, Lebanon.
authors.forename: Anthony
authors.initials: A
authors.lastname: Mansour
authors.affiliation: Friedman School of Nutrition Science and Policy, Tufts University, Boston, MA.
authors.forename: Kathryn
authors.initials: K
authors.lastname: Spielman
authors.affiliation: Centre de Diagnostic, Hopital Hotel-Dieu, Paris, France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Blacher
authors.affiliation: Centre de Diagnostic, Hopital Hotel-Dieu, Paris, France.
authors.forename: Michel E
authors.initials: ME
authors.lastname: Safar
authors.affiliation: Lebanese American University School of Medicine, Lebanon. sola.bahous@lau.edu.lb.|Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon. sola.bahous@lau.edu.lb.
authors.forename: Sola Aoun
authors.initials: SA
authors.lastname: Bahous
mesh_terms: D000328:Adult; D000368:Aged; D002318:Cardiovascular Diseases / Q000453:epidemiology* / Q000209:etiology; D002339:Carotid Arteries / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D063177:Pulse Wave Analysis / Q000379:methods*; D012044:Regression Analysis; D006435:Renal Dialysis / Q000009:adverse effects*; D059289:Vascular Stiffness