title: Quality of documentation on antibiotic therapy in medical records: evaluation of combined interventions in a teaching hospital by repeated point prevalence survey.
abstract: This study aimed to improve the quality of documentation on antibiotic therapy in the computerized medical records of inpatients. A prospective, uncontrolled, interrupted time series (ITS) study was conducted by repeated point prevalence survey (PPS) to audit the quality of documentation on antibiotic therapy in the medical records before and after a combined intervention strategy (implementation of guidelines, distribution of educational materials, educational outreach visits, group educational interactive sessions) from the antimicrobial stewardship team (AST) in the academic teaching hospital (CHU) of Liège, Belgium. The primary outcome measure was the documentation rate on three quality indicators in the computerized medical records: (1) indication for treatment, (2) antibiotics prescribed, and (3) duration or review date. Segmented regression analysis was used to analyze the ITS. The medical records of 2306 patients receiving antibiotics for an infection (1177 in the pre-intervention period and 1129 in the post-intervention period) were analyzed. A significant increase in mean percentages in the post-intervention period was observed as compared with the pre-intervention period for the three quality indicators (indication documented 83.4 ± 10.4 % vs. 90.3 ± 6.6 %, p = 0.0013; antibiotics documented 87.9 ± 9.0 % vs. 95.6 ± 5.1 %, p < 0.0001; and duration or review date documented 31.9 ± 15.4 % vs. 67.7 ± 15.2 %, p < 0.0001). The study demonstrated the successful implementation of a combined intervention strategy from the AST. This strategy was associated with significant changes in the documentation rate in the computerized medical records for the three quality indicators.
authors.affiliation: Department of Clinical Pharmacy, CIRM (Center for Interdisciplinary Research on Medicines), University Hospital of Liège, Liège, Belgium. christelle.vercheval@chu.ulg.ac.be.|Service de Pharmacie Clinique, CHU de Liège, Avenue de l'hôpital, 1 - B35, Sart Tilman, 4000, Liège, Belgium. christelle.vercheval@chu.ulg.ac.be.
authors.forename: C
authors.initials: C
authors.lastname: Vercheval
authors.affiliation: Department of Clinical Pharmacy, CIRM (Center for Interdisciplinary Research on Medicines), University Hospital of Liège, Liège, Belgium.
authors.forename: M
authors.initials: M
authors.lastname: Gillet
authors.affiliation: Department of Biostatistics and Medico-Economic Information, University Hospital of Liège, Liège, Belgium.
authors.forename: N
authors.initials: N
authors.lastname: Maes
authors.affiliation: Department of Biostatistics and Medico-Economic Information, University Hospital of Liège, Liège, Belgium.
authors.forename: A
authors.initials: A
authors.lastname: Albert
authors.affiliation: Department of Infectious Diseases and General Internal Medicine, University Hospital of Liège, Liège, Belgium.
authors.forename: F
authors.initials: F
authors.lastname: Frippiat
authors.affiliation: Department of Intensive Care Unit, University Hospital of Liège, Liège, Belgium.
authors.forename: P
authors.initials: P
authors.lastname: Damas
authors.affiliation: Department of Clinical Pharmacy, CIRM (Center for Interdisciplinary Research on Medicines), University Hospital of Liège, Liège, Belgium.
authors.forename: T
authors.initials: T
authors.lastname: Van Hees
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D001530:Belgium; D004282:Documentation; D004363:Drug Utilization; D057286:Electronic Health Records; D005260:Female; D006784:Hospitals, Teaching; D006801:Humans; D008297:Male; D008875:Middle Aged; D011795:Surveys and Questionnaires
chemical_list: D000900:Anti-Bacterial Agents