title: Intravital imaging reveals new ancillary mechanisms co-opted by cancer cells to drive tumor progression.
abstract: Intravital imaging is providing new insights into the dynamics of tumor progression in native tissues and has started to reveal the layers of complexity found in cancer. Recent advances in intravital imaging have allowed us to look deeper into cancer behavior and to dissect the interactions between tumor cells and the ancillary host niche that promote cancer development. In this review, we provide an insight into the latest advances in cancer biology achieved by intravital imaging, focusing on recently discovered mechanisms by which tumor cells manipulate normal tissue to facilitate disease progression.
authors.affiliation: The Kinghorn Cancer Centre, Cancer Division, The Garvan Institute of Medical Research, Sydney, NSW, Australia.|St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors.forename: Claire
authors.initials: C
authors.lastname: Vennin
authors.affiliation: The Kinghorn Cancer Centre, Cancer Division, The Garvan Institute of Medical Research, Sydney, NSW, Australia.|St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors.forename: David
authors.initials: D
authors.lastname: Herrmann
authors.affiliation: The Kinghorn Cancer Centre, Cancer Division, The Garvan Institute of Medical Research, Sydney, NSW, Australia.|St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors.forename: Morghan C
authors.initials: MC
authors.lastname: Lucas
authors.affiliation: The Kinghorn Cancer Centre, Cancer Division, The Garvan Institute of Medical Research, Sydney, NSW, Australia.|St Vincent's Clinical School, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia.
authors.forename: Paul
authors.initials: P
authors.lastname: Timpson
keywords: Intravital imaging; tumor progression