title: Emergency transcatheter aortic valve implantation in patients with severe aortic regurgitation and a left ventricle assist device: A case report and systematic review.
abstract: BACKGROUND
  Cardiogenic shock due to severe aortic regurgitation in patients with left ventricle assist devices is a life threatening condition. Here, we consider transcatheter aortic valve implantation as a treatment option.
  
  
  RESULTS
  A patient with a left ventricle assist device was presented to us with cardiogenic shock due to severe aortic regurgitation. We successfully implanted a transcatheter aortic valve in emergency setting. The patient recovered and underwent cardiac transplantation three months afterwards. We performed a systematic literature review and identified 10 cases of patients with a left ventricle assist device undergoing transcatheter aortic valve implantation. In these cases, there was no procedural related mortality reported. In four (40%) patients, transcatheter aortic valve implantation resulted in significant paravalvular aortic regurgitation. In two of these cases it was due to migration of the valve towards the left ventricle.
  
  
  CONCLUSIONS
  Our case report and review of literature suggests that transcatheter aortic valve implantation is a feasible and lifesaving treatment option for left ventricle assist device patients presenting with severe aortic regurgitation.
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Hindrik W
authors.initials: HW
authors.lastname: van der Werf
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Remco Aj
authors.initials: RA
authors.lastname: Schurer
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Ton E
authors.initials: TE
authors.lastname: Vonck
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Janny E
authors.initials: JE
authors.lastname: Poelman
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Aafke A
authors.initials: AA
authors.lastname: Klungel
authors.affiliation: 2 Department of Anaesthesiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Vladimir
authors.initials: V
authors.lastname: Cernak
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Ad Fm
authors.initials: AF
authors.lastname: van den Heuvel
authors.affiliation: 1 Department of Cardiology, University of Groningen, University Medical Centre Groningen, The Netherlands.
authors.forename: Pim
authors.initials: P
authors.lastname: van der Harst
mesh_terms: D000328:Adult; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D002311:Cardiomyopathy, Dilated / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D004452:Echocardiography; D004630:Emergencies; D006350:Heart Valve Prosthesis; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D008297:Male; D065467:Transcatheter Aortic Valve Replacement / Q000379:methods*
keywords: Aortic regurgitation; left ventricle assist device; transcatheter aortic valve implantations