title: Early clinical outcomes of right ventricular outflow tract reconstruction with small caliber bovine jugular vein conduit (Contegra®) in small children.
abstract: This study reviewed early clinical outcomes of right ventricular outflow tract reconstruction with Contegra®valved conduits in pediatric patients. Between April 2013 and July 2014, thirteen pediatric patients underwent right ventricular outflow tract reconstruction with Contegra valved conduits. The size of the implanted conduits were 12 mm in 5 patients, 14 mm in 3, 16 mm in 3, and then 2 patients were implanted with bicuspidized conduits for downsizing the conduit to 9 and 10 mm in each. Follow-ups were completed in all patients. One conduit was explanted 7 days after a neonatal biventricular repair for Ebstein's anomaly and pulmonary atresia, timed to be at the point of conversion to a single ventricular palliation. Among the 5 patients who developed significant pulmonary insufficiency and/or conduit stenosis, 3 patients exhibited persistent pulmonary hypertension. Both the bicuspidized conduits resulted in early pulmonary insufficiency. One patient implanted with a ring-supported conduit developed coronary artery stenosis, caused by suppression between the ring of the implanted conduit and the annulus of the mechanical vale. Although the small caliber Contegra valved conduit might be an alternative to RVOT reconstruction, the indication should be carefully considered. More than mild pulmonary hypertension, and low body weight at operation of less than 3.0 kg caused early conduit dysfunction.
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, 5-7-1, Fujishirodai, Suita, 565-8565, Osaka, Japan.|Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kido
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, 5-7-1, Fujishirodai, Suita, 565-8565, Osaka, Japan. thoashi@surg1.med.osaka-u.ac.jp.
authors.forename: Takaya
authors.initials: T
authors.lastname: Hoashi
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, 5-7-1, Fujishirodai, Suita, 565-8565, Osaka, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Kagisaki
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, 5-7-1, Fujishirodai, Suita, 565-8565, Osaka, Japan.|Department of Cardiovascular Surgery, Tokyo Medical University, Hachioji, Japan.
authors.forename: Toshiki
authors.initials: T
authors.lastname: Fujiyoshi
authors.affiliation: Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Masataka
authors.initials: M
authors.lastname: Kitano
authors.affiliation: Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Kenichi
authors.initials: K
authors.lastname: Kurosaki
authors.affiliation: Department of Pediatric Cardiology, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
authors.forename: Isao
authors.initials: I
authors.lastname: Shiraishi
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, 5-7-1, Fujishirodai, Suita, 565-8565, Osaka, Japan.
authors.forename: Toshikatsu
authors.initials: T
authors.lastname: Yagihara
authors.affiliation: Department of Cardiovascular Surgery, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Sawa
authors.affiliation: Department of Pediatric Cardiovascular Surgery, National Cerebral and Cardiovascular Center, Suita, 5-7-1, Fujishirodai, Suita, 565-8565, Osaka, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Ichikawa
mesh_terms: D000818:Animals; D001705:Bioprosthesis / Q000009:adverse effects / Q000706:statistics & numerical data; D002417:Cattle; D002675:Child, Preschool; D023921:Coronary Stenosis / Q000209:etiology; D006330:Heart Defects, Congenital / Q000601:surgery*; D006350:Heart Valve Prosthesis / Q000009:adverse effects* / Q000706:statistics & numerical data; D019918:Heart Valve Prosthesis Implantation; D006352:Heart Ventricles / Q000601:surgery; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007601:Jugular Veins / Q000637:transplantation*; D011664:Pulmonary Valve / Q000601:surgery; D011665:Pulmonary Valve Insufficiency / Q000209:etiology; D012189:Retrospective Studies; D016896:Treatment Outcome; D014694:Ventricular Outflow Obstruction / Q000601:surgery*
keywords: Congenital heart surgery; Contegra valved conduit; Right ventricular outflow tract reconstruction