title: Pharmacotherapy for Substance Use Disorders.
abstract: This article reviews the current pharmacotherapy options available for the treatment of patients with substance use disorders. In the United States there are medications available to treat tobacco use disorders (nicotine replacement, bupropion, and varenicline), alcohol use disorders (naltrexone and acamprosate), and opioid use disorders (methadone and buprenorphine). These medications are likely underused and physicians should more readily prescribe for eligible patients.
authors.affiliation: Division of General Internal Medicine, Department of Medicine, Harborview Medical Center, University of Washington, 325 Ninth Avenue, Box 359780, Seattle, WA 98104, USA. Electronic address: jaredwk@uw.edu.
authors.forename: Jared Wilson
authors.initials: JW
authors.lastname: Klein
mesh_terms: D000367:Age Factors; D000427:Alcohol Deterrents / Q000627:therapeutic use; D000437:Alcoholism / Q000175:diagnosis / Q000188:drug therapy; D000928:Antidepressive Agents / Q000627:therapeutic use; D002047:Buprenorphine / Q000627:therapeutic use; D016642:Bupropion / Q000627:therapeutic use; D004359:Drug Therapy, Combination; D006801:Humans; D008691:Methadone / Q000627:therapeutic use; D009271:Naltrexone / Q000627:therapeutic use; D009292:Narcotic Antagonists / Q000627:therapeutic use; D058850:Opiate Substitution Treatment / Q000379:methods; D009293:Opioid-Related Disorders / Q000188:drug therapy; D012008:Recurrence; D013375:Substance Withdrawal Syndrome / Q000188:drug therapy; D019966:Substance-Related Disorders / Q000175:diagnosis / Q000188:drug therapy*; D061485:Tobacco Use Cessation Devices; D014029:Tobacco Use Disorder / Q000188:drug therapy; D000068580:Varenicline / Q000627:therapeutic use
chemical_list: D000427:Alcohol Deterrents; D000928:Antidepressive Agents; D009292:Narcotic Antagonists; D016642:Bupropion; D002047:Buprenorphine; D009271:Naltrexone; D008691:Methadone; D000068580:Varenicline
keywords: Buprenorphine; Methadone; Naltrexone; Substance use disorder; Varenicline