title: Visualization of electrical field of electrode using voltage-controlled fluorescence release.
abstract: In this study we propose an approach to directly visualize electrical current distribution at the electrode-electrolyte interface of a biopotential electrode. High-speed fluorescent microscopic images are acquired when an electric potential is applied across the interface to trigger the release of fluorescent material from the surface of the electrode. These images are analyzed computationally to obtain the distribution of the electric field from the fluorescent intensity of each pixel. Our approach allows direct observation of microscopic electrical current distribution around the electrode. Experiments are conducted to validate the feasibility of the fluorescent imaging method.
authors.affiliation: Department of Neurosurgery, University of Pittsburgh, PA 15260, USA. Electronic address: wej6@pitt.edu.
authors.forename: Wenyan
authors.initials: W
authors.lastname: Jia
authors.affiliation: Department of Chemical and Petroleum Engineering, University of Pittsburgh, PA 15260, USA.
authors.forename: Jiamin
authors.initials: J
authors.lastname: Wu
authors.affiliation: Department of Chemical and Petroleum Engineering, University of Pittsburgh, PA 15260, USA.
authors.forename: Di
authors.initials: D
authors.lastname: Gao
authors.affiliation: Department of Electrical and Computer Engineering, University of Pittsburgh, PA 15260, USA.
authors.forename: Hao
authors.initials: H
authors.lastname: Wang
authors.affiliation: Department of Neurosurgery, University of Pittsburgh, PA 15260, USA; Department of Electrical and Computer Engineering, University of Pittsburgh, PA 15260, USA.
authors.forename: Mingui
authors.initials: M
authors.lastname: Sun
mesh_terms: D002460:Cell Line; D004566:Electrodes; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D008856:Microscopy, Fluorescence
chemical_list: D005456:Fluorescent Dyes
keywords: Electrical current distribution; Electrode–electrolyte interface; Fluorescent tracer