title: Endoscopic low-temperature plasma radiofrequency ablation for laryngeal plexiform neurobromatosis-1 in an infant: Case report and review of the literature.
abstract: To evaluate the feasibility and effectiveness of using endoscopic low-temperature plasma radiofrequency ablation (RFA) for treatment of laryngeal plexiform neurofibromatosis-1 (NF-1). An infant diagnosed as laryngeal plexiform NF-1 based on a detailed medical history, as well as physical, laboratory, and pathological examinations, was treated under general anesthesia with low-temperature plasma RFA in combination with a self-retaining laryngoscope and high definition camera system.The laryngeal plexiform NF-1 tumor was successfully excised using endoscopic low-temperature plasma RFA without complications. Following surgery, the infant displayed an uneventful recovery and no disease recurrence during a 2-year follow-up period. low-temperature plasma RFA is a feasible and effective method for treating laryngeal plexiform NF-1, and has advantages of producing minimal bleeding, providing complete removal of the tumor, and causing only slight degrees of trauma and postoperative tissue reaction.
authors.forename: Zhinan
authors.initials: Z
authors.lastname: Wang
authors.forename: Yamin
authors.initials: Y
authors.lastname: Zhang
authors.forename: Hua
authors.initials: H
authors.lastname: Cui
authors.forename: Wei
authors.initials: W
authors.lastname: Yao
mesh_terms: D017115:Catheter Ablation / Q000295:instrumentation* / Q000379:methods; D016145:Endoscopy, Digestive System / Q000379:methods; D006801:Humans; D007223:Infant; D007822:Laryngeal Neoplasms / Q000601:surgery*; D008297:Male; D018318:Neurofibroma, Plexiform / Q000601:surgery*; D013696:Temperature
keywords: Neurofibromatosis; laryngeal plexiform neurofibromatosis type-1; laryngemphraxis; low-temperature plasma radiofrequency ablation