title: Dose and Image Quality in Low-dose CT for Urinary Stone Disease: Added Value of Automatic Tube Current Modulation and Iterative Reconstruction Techniques.
abstract: The aim of this study was to compare dose and image quality (IQ) of a baseline low-dose computed tomography (CT) (fix mAs) vs. an ultra-low-dose CT (automatic tube current modulation, ATCM) in patients with suspected urinary stone disease and to assess the added value of iterative reconstruction. CT examination was performed on 193 patients (103 baseline low-dose, 90 ultra-low-dose). Filtered back projection (FBP) was used for both protocols, and Sinogram Affirmed Iterative Reconstruction (SAFIRE) was used for the ultra-low-dose protocol only. Dose and ureter stones information were collected for both protocols. Subjective IQ was assessed by two radiologists scoring noise, visibility of the ureter and overall IQ. Objective IQ (contrast-to-noise ratio, CNR) was assessed for the ultra-low-dose protocol only (FBP and SAFIRE). The ultra-low-dose protocol (ATCM) showed a 22% decrease in mean effective dose (p < 0.001) and improved visibility of the pelvic ureter (p = 0.02). CNR was higher for SAFIRE (p < 0.0001). SAFIRE improves the objective IQ, but not the subjective IQ for the chosen clinical task.
authors.affiliation: Department of Radiology, University Hospitals Leuven, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
authors.forename: Olivier
authors.initials: O
authors.lastname: Soenen
authors.affiliation: Department of Radiology, University Hospitals Leuven, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
authors.forename: Christophe
authors.initials: C
authors.lastname: Balliauw
authors.affiliation: Department of Radiology, University Hospitals Leuven, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.|Department of imaging and Pathology, University Hospitals Leuven, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
authors.forename: Raymond
authors.initials: R
authors.lastname: Oyen
authors.affiliation: Department of Radiology, University Hospitals Leuven, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.|Department of imaging and Pathology, University Hospitals Leuven, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium.
authors.forename: Federica
authors.initials: F
authors.lastname: Zanca
mesh_terms: D000465:Algorithms; D001331:Automation; D006801:Humans; D011829:Radiation Dosage; D011857:Radiographic Image Interpretation, Computer-Assisted; D014057:Tomography, X-Ray Computed; D014545:Urinary Calculi / Q000000981:diagnostic imaging*