title: Chirality and catalysis with aromatic N-fused heterobicyclic carbenes.
abstract: The benzoannulation of the most common families of aromatic NHCs, imidazol-2-ylidenes and 1,2,4-triazol-3-ylidenes, results in heterobicyclic imidazo[1,5-a]pyridin-3-ylidenes ('s) and [1,2,4]triazolo[4,3-a]pyridin-3-ylidenes ('s), characterized by a bridged N atom. These are versatile platforms that offer multiple possibilities for the modulation of the steric and electronic properties of the carbene ligand and/or organocatalyst, and offer also diverse opportunities for the introduction of several types of chiralities. In this paper the different families of chiral and carbenes and their application in asymmetric catalysis will be discussed.
authors.affiliation: Departamento de Química Orgánica, Universidad de Sevilla and Centro de Innovación en Química Avanzada (ORFEO-CINQA), C/Prof. García González, 1, 41012 Sevilla, Spain. ediez@us.es ffernan@us.es.
authors.forename: Javier
authors.initials: J
authors.lastname: Iglesias-Sigüenza
authors.affiliation: Departamento de Química Orgánica, Universidad de Sevilla and Centro de Innovación en Química Avanzada (ORFEO-CINQA), C/Prof. García González, 1, 41012 Sevilla, Spain. ediez@us.es ffernan@us.es.
authors.forename: Cristina
authors.initials: C
authors.lastname: Izquierdo
authors.affiliation: Departamento de Química Orgánica, Universidad de Sevilla and Centro de Innovación en Química Avanzada (ORFEO-CINQA), C/Prof. García González, 1, 41012 Sevilla, Spain. ediez@us.es ffernan@us.es.
authors.forename: Elena
authors.initials: E
authors.lastname: Díez
authors.affiliation: Departamento de Química Orgánica, Universidad de Sevilla and Centro de Innovación en Química Avanzada (ORFEO-CINQA), C/Prof. García González, 1, 41012 Sevilla, Spain. ediez@us.es ffernan@us.es.
authors.forename: Rosario
authors.initials: R
authors.lastname: Fernández
authors.affiliation: Instituto de Investigaciones Químicas (CSIC-US) and Centro de Innovación en Química Avanzada (ORFEO-CINQA), Avda. Américo Vespucio, 49, 41092 Sevilla, Spain. jmlassa@iiq.csic.es.
authors.forename: José M
authors.initials: JM
authors.lastname: Lassaletta