title: Tumor Organoids Fill the Niche.
abstract: Organoid technologies have significant potential as effective patient avatars. Fujii et al. (2016) and van de Wetering et al. (2015) derive biobanks of colorectal tumor and matching normal organoids and identify associations between tumor subtype, oncogenic drivers, gene-drug interactions, and varying niche requirements for tumor organoid growth, engraftment, and metastasis.
authors.affiliation: Associate Professor of Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA. Electronic address: noah.shroyer@bcm.edu.
authors.forename: Noah F
authors.initials: NF
authors.lastname: Shroyer
mesh_terms: D063646:Carcinogenesis; D015179:Colorectal Neoplasms; D006801:Humans; D009940:Organoids / Q000187:drug effects*