title: Association between nutrient intake and thyroid cancer risk in Korean women.
abstract: OBJECTIVE
  The incidence of thyroid cancer has increased in many countries, including Korea. International differences in the incidence of thyroid cancer may indicate a role of diet, but findings from previous studies are inconclusive. Therefore, we aimed to investigate the roles of nutrients in thyroid cancer risk in Korean women.
  
  
  METHODS
  We conducted a case-control study comprising 113 cases and 226 age-matched controls. Nutrient intake was assessed using a validated food frequency questionnaire, and the association between nutrient intake and thyroid cancer risk was estimated using a logistic regression model.
  
  
  RESULTS
  We found that high calcium intake was associated with a reduced risk of thyroid cancer (OR [95% CI] = 0.55 [0.35-0.89]). Significant associations were observed among subjects who were older than 50 years, had low BMI, and had low calorie intake. However, other nutrients included in this study did not show any significant associations with thyroid cancer risk.
  
  
  CONCLUSIONS
  This study suggested a possible protective effect of calcium on thyroid cancer risk. Well-designed prospective studies are required to confirm these findings.
authors.affiliation: Molecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Gyeonggi 10408, Korea.
authors.forename: Young Ae
authors.initials: YA
authors.lastname: Cho
authors.affiliation: Molecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Gyeonggi 10408, Korea.
authors.forename: Jeonghee
authors.initials: J
authors.lastname: Lee
authors.affiliation: Molecular Epidemiology Branch, Division of Cancer Epidemiology and Prevention, Research Institute, National Cancer Center, 323, Ilsan-ro, Ilsandong-gu, Gyeonggi 10408, Korea.
authors.forename: Jeongseon
authors.initials: J
authors.lastname: Kim
keywords: Korean; Thyroid cancer; calcium; nutrient