title: Recent Advances in the Reactions of 1,2-Allenic Ketones and α-Allenic Alcohols.
abstract: This Personal Account summarizes our recent efforts in searching for novel synthetic strategies for a number of organic molecules by using allene derivatives as valuable substrates. It starts with a concise description of the background of allene-related synthetic chemistry. The second part deals with the reactions of 1,2-allenic ketones, including the reactions of 1,2-allenic ketones with various nucleophiles to afford functionalized benzenes, heterocycles, and fluoroenones, and those of allenic ketones as nucleophiles under the promotion of bases to provide 1,3,4'-triones or functionalized furans. The third part of this account focuses on the reactions of α-allenic alcohols. In this section, multicomponent reactions involving α-allenic alcohols, and cascade reactions of α-allenic alcohols promoted by Brønsted acid or iodine, are presented.
authors.affiliation: School of Chemistry and Chemical Engineering Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions Ministry of Education, Henan Normal University, 46 East Jianshe Road, Xinxiang, Henan, 453007, P. R. China.
authors.forename: Xuesen
authors.initials: X
authors.lastname: Fan
authors.affiliation: School of Environment Henan Normal University, 46 East Jianshe Road, Xinxiang, Henan, 453007, P. R. China.
authors.forename: Yan
authors.initials: Y
authors.lastname: He
authors.affiliation: School of Chemistry and Chemical Engineering Collaborative Innovation Center of Henan Province for Green Manufacturing of Fine Chemicals Key Laboratory of Green Chemical Media and Reactions Ministry of Education, Henan Normal University, 46 East Jianshe Road, Xinxiang, Henan, 453007, P. R. China.
authors.forename: Xinying
authors.initials: X
authors.lastname: Zhang
keywords: allenic alcohols; allenic ketones; domino reactions; multicomponent reactions; synthetic methods