title: Editorial: A New Spin on Magnetic Resonance Elastography.
abstract: The development of hepatic fibrosis is the hallmark of liver disease progression. Identifying fibrosis across the spectrum, from early stages to cirrhosis has become a major unmet need. Newer imaging techniques that measure liver elastography (stiffness) as a surrogate of fibrosis seem to outperform serum tests. The current study compares two-dimensional (2D) gradient-recalled echo magnetic resonance elastography (MRE) to three-dimensional (3D) spin-echo echo-planar imaging MRE. 3D-SE-EPI MRE was able to image more liver volume in less time with fewer technical failures. The current study demonstrates that 3D-SE-EPI MRE appears marginally superior to 2D-GRE and may evolve into the new gold standard.
authors.affiliation: Department of Radiology, Virginia Commonwealth University Health System, Richmond, Virginia, USA.
authors.forename: Rekha
authors.initials: R
authors.lastname: Kishore
authors.affiliation: NAFLD Research Center, Division of Gastroenterology and Epidemiology, University of California at San Diego, La Jolla, California, USA.
authors.forename: Rohit
authors.initials: R
authors.lastname: Loomba
authors.affiliation: Division of Gastroenterology, Hepatology, and Nutrition, Virginia Commonwealth University Health System, Richmond, Virginia, USA.
authors.forename: Richard K
authors.initials: RK
authors.lastname: Sterling
mesh_terms: D018450:Disease Progression; D017352:Echo-Planar Imaging; D054459:Elasticity Imaging Techniques; D006801:Humans; D008103:Liver Cirrhosis; D008279:Magnetic Resonance Imaging