title: Novel chiral Schiff base/Ti(iv) catalysts for the catalytic asymmetric epoxidation of N-alkenyl sulfonamides.
abstract: A new method has been developed for the catalytic asymmetric epoxidation of N-alkenyl sulfonamides in the presence of a Schiff base derived from hydroquinine and Ti(Oi-Pr)4. This reaction proceeds under mild conditions, providing facile access to chiral epoxy sulfonamides in good yields (up to 95%) with excellent enantioselectivities (up to 97% ee).
authors.affiliation: Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, P. R. China. weihechem@fmmu.edu.cn.
authors.forename: Nan
authors.initials: N
authors.lastname: Ji
authors.affiliation: Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, P. R. China. weihechem@fmmu.edu.cn.
authors.forename: Jiani
authors.initials: J
authors.lastname: Yuan
authors.affiliation: Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, P. R. China. weihechem@fmmu.edu.cn.
authors.forename: Miaoxi
authors.initials: M
authors.lastname: Liu
authors.affiliation: Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, P. R. China. weihechem@fmmu.edu.cn.
authors.forename: Ting
authors.initials: T
authors.lastname: Lan
authors.affiliation: Department of Chemistry, School of Pharmacy, Fourth Military Medical University, Xi'an 710032, P. R. China. weihechem@fmmu.edu.cn.
authors.forename: Wei
authors.initials: W
authors.lastname: He