title: Regioselective Nitration of Halogenated Benzo[c]cinnolines and Benzenoids.
abstract: Electrophilic nitration of halo-substituted benzo[c]cinnolines and benzenoids has been achieved regioselectively. The nitro group entry was always ortho to the halo group or/and the aromatic ring. This regioselective electrophilic ortho-nitration was accomplished in mixed acid/mild temperature conditions. Regioselectivity ortho to the halo/ring group(s) was observed with or without proximal steric hindrance. Chlorides and bromides worked equally well in directing these high-yielding ortho-selective reactions.
authors.affiliation: Albany State University, Albany GA.
authors.forename: Ayunna K
authors.initials: AK
authors.lastname: Epps
authors.affiliation: Albany State University, Albany GA.
authors.forename: Tonya M
authors.initials: TM
authors.lastname: Horne
authors.affiliation: Albany State University, Albany GA.
authors.forename: ShaNese
authors.initials: S
authors.lastname: Jackson
authors.affiliation: Albany State University, Albany GA.
authors.forename: Bridgette
authors.initials: B
authors.lastname: Sands
authors.affiliation: Albany State University, Albany GA.
authors.forename: Ghislain
authors.initials: G
authors.lastname: Mandouma