title: Cutaneous paraneoplastic disorders in stomach cancer: Collaboration between oncologically active dermatologists and clinical oncologists.
abstract: To our knowledge this is the first systemic review that provides an overview of the cutaneous paraneoplastic syndromes (CPS) (i.e., clinical manifestations, pathomechanisms, and treatment modalities) occurring in stomach cancer. CPS are caused by substances produced by stomach cancer and may precede, coincide with, or follow the diagnosis of this malignancy. More than 20 possible CPS in association with stomach cancer have been identified. CPS mostly compromises the patient's quality of life by skin impairment plus discomfort and are often associated with a dismal prognosis on survival. Studies of these CPS not only in stomach cancer have partially contributed to the understanding of pathomechanism and since CPS may be the presenting sign of an occult cancer, cognizance of their features and clinical implications are of considerable importance. Patients with these syndromes should have an appropriate work-up for a possibly occult malignancy with consecutive successful early treatment.
authors.affiliation: Comprehensive Cancer Center-GET, Medical University of Vienna, Vienna, Austria. Electronic address: hejna@meduniwien.ac.at.
authors.forename: Michael
authors.initials: M
authors.lastname: Hejna
authors.affiliation: St.Vinzenz Krankenhaus Betriebs GmbH, Zams, Austria.
authors.forename: Ewald
authors.initials: E
authors.lastname: Wöll
authors.affiliation: Department of Dermatology, Medical University of Vienna, Vienna, Austria.
authors.forename: Philipp
authors.initials: P
authors.lastname: Tschandl
authors.affiliation: Department of Internal Medicine I, Division of Oncology Medical University of Vienna, Vienna, Austria.
authors.forename: Markus
authors.initials: M
authors.lastname: Raderer
mesh_terms: D003937:Diagnosis, Differential; D006801:Humans; D010348:Patient Care Team; D011788:Quality of Life; D012871:Skin Diseases / Q000175:diagnosis / Q000209:etiology*; D013274:Stomach Neoplasms / Q000150:complications*
keywords: Cutaneous paraneoplastic syndromes; Gastric cancer; Skin lesions; Stomach cancer