title: Coherent-weighted three-dimensional image reconstruction in linear-array-based photoacoustic tomography.
abstract: While the majority of photoacoustic imaging systems used custom-made transducer arrays, commercially-available linear transducer arrays hold the benefits of affordable price, handheld convenience and wide clinical recognition. They are not widely used in photoacoustic imaging primarily because of the poor elevation resolution. Here, without modifying the imaging geometry and system, we propose addressing this limitation purely through image reconstruction. Our approach is based on the integration of two advanced image reconstruction techniques: focal-line-based three-dimensional image reconstruction and coherent weighting. We first numerically validated our approach through simulation and then experimentally tested it in phantom and in vivo. Both simulation and experimental results proved that the method can significantly improve the elevation resolution (up to 4 times in our experiment) and enhance object contrast.
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, USA.
authors.forename: Depeng
authors.initials: D
authors.lastname: Wang
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, USA.
authors.forename: Yuehang
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, USA; College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Functionalized Probes for Chemical Imaging in Universities of Shandong, Key Laboratory of Molecular and Nano Probes, Ministry of Education, Shandong Provincial Key Laboratory of Clean Production of Fine Chemicals, Shandong Normal University, Jinan, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, USA.
authors.forename: Jonathan F
authors.initials: JF
authors.lastname: Lovell
authors.affiliation: Department of Biomedical Engineering, University at Buffalo, State University of New York, Buffalo, USA.
authors.forename: Jun
authors.initials: J
authors.lastname: Xia
keywords: (100.0100) Image processing; (110.5120) Photoacoustic imaging; (110.5125) Photoacoustics