title: [Testicular Cancer: Diagnostics, Therapy and Follow Up].
abstract: Germ cell tumours represent a rare malignancy that affects mostly young men between 15 and 40 years of age. In approximately 50 % of the cases pure seminoma is found, 50 % non-seminomas are divided into hetrogenous subgroups. The initial therapeutic step usually is orchiectomy, further procedures are defined by histology, clinical staging and risk profile.Therpeutical options consist in active surveillance, radiotherapy or chemotherapy. Stage I shows a cure rate of almost 100 %but even in metastatic stages more then 80 % of all patients can be cured. However they must remain in a close longterm followup during which especially cardiovascular risk factors have to be monitored.
authors.affiliation: 1 Medizinische Onkologie, Kantonsspital Winterthur.
authors.forename: Martin
authors.initials: M
authors.lastname: Kälin
authors.affiliation: 1 Medizinische Onkologie, Kantonsspital Winterthur.
authors.forename: Laetitia
authors.initials: L
authors.lastname: Mauti
authors.affiliation: 1 Medizinische Onkologie, Kantonsspital Winterthur.
authors.forename: Miklos
authors.initials: M
authors.lastname: Pless
mesh_terms: D000293:Adolescent; D000328:Adult; D014408:Biomarkers, Tumor / Q000097:blood; D003131:Combined Modality Therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D009373:Neoplasms, Germ Cell and Embryonal / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D009919:Orchiectomy; D011379:Prognosis; D018239:Seminoma / Q000175:diagnosis / Q000473:pathology / Q000628:therapy; D013736:Testicular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000628:therapy*; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor
keywords: Chemotherapie; Hodenkarzinom; Nachsorge; Tumormarker; cancer des testicules; chemotherapy; chimiothérapie; follow up; marqueurs tumoraux; serum tumor markers; suivi des patients; surveillance; testicular cancer; Überwachung