title: Primary Malignant Melanoma of Renal Pelvis with Extensive Clear Cell Change.
abstract: Our presentation illustrates a rare case of primary renal pelvis malignant melanoma in a 35-year-old man. The diagnosis of malignant melanoma was based on immunophenotype and the detection of intracellular melanin pigment. The renal origin was proven by the presence of scattered melanocytes within the urothelium of the pelvis. The tumor exhibited extensive clear cell change that closely mimics clear cell renal cell carcinoma. The patient's clinical history did not disclose any signs of previous melanocytic skin or mucosa lesions. Differential diagnosis includes tumors capable of synthesizing melanin or expressing melanocytic markers.
authors.affiliation: 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens.
authors.forename: George
authors.initials: G
authors.lastname: Liapis
authors.affiliation: 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens.
authors.forename: Helen
authors.initials: H
authors.lastname: Sarlanis
authors.affiliation: 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens.
authors.forename: Elpida
authors.initials: E
authors.lastname: Poulaki
authors.affiliation: 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens.
authors.forename: Konstandinos
authors.initials: K
authors.lastname: Stravodimos
authors.affiliation: Medical School, La Sapienza University of Rome.
authors.forename: Olga
authors.initials: O
authors.lastname: Riccioni
authors.affiliation: 1st Department of Pathology, School of Medicine, National and Kapodistrian University of Athens.
authors.forename: Andreas C
authors.initials: AC
authors.lastname: Lazaris
keywords: clear cell; kidney; melanoma; pelvis; primary