title: Recent Advances in Diverticular Disease.
abstract: Diverticular disease is common and accounts for substantial health care utilization in the USA. Recent publications in the areas of diverticulosis and diverticular disease have highlighted several notable advances that are now changing practice. Despite colonic diverticula being common, only 1-4 % of individuals with colonic diverticula will develop diverticulitis. After a first occurrence of acute diverticulitis, the risk of recurrence is 20 % at 5 years. Complications most commonly occur with the first occurrence of acute diverticulitis and not with recurrent episodes. After an episode of diverticulitis, many patients continue to experience chronic gastrointestinal symptoms. Prophylactic surgery is an option to reduce the risk of recurrence and its negative impact on quality of life. Importantly, the rationale for surgery is no longer to prevent complications because this risk is low. The review concludes with practical recommendations for patients with diverticulosis and diverticular disease.
authors.affiliation: University of North Carolina School of Medicine, Chapel Hill, NC, USA. Anne_Peery@med.unc.edu.|Division of Gastroenterology and Hepatology, University of North Carolina School of Medicine, Bioinformatics Building, CB # 7080, 130 Mason Farm Road, Chapel Hill, NC, 27599-7555, USA. Anne_Peery@med.unc.edu.
authors.forename: Anne F
authors.initials: AF
authors.lastname: Peery
mesh_terms: D000208:Acute Disease; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003082:Colectomy; D004238:Diverticulitis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000628:therapy*; D043963:Diverticulosis, Colonic / Q000150:complications / Q000453:epidemiology / Q000628:therapy*; D006801:Humans; D012008:Recurrence; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents
keywords: Colectomy; Colostomy; Complicated diverticulitis; Diverticulitis; Diverticulosis; Prevention