title: Jaw tumor in primary hyperparathyroidism is not always a brown tumor.
abstract: Primary hyperparthyrodism (PHPT) is a common endocrine disease. It results from an inappropriate parathyroid hormone (PTH) secretion relative to serum ionized calcium level. Clinical manifestation of severe PHPT include bone disease called osteitis fibrosa cystica which reflects an increase osteoclastic resorption and osteoblastic activity. This high bone turnover is responsible of the occurrence of osteoclastomas, also named "brown tumors" (1). Rarely, PHPT may occur in inherited forms with association to fibrous jaw tumor that are unrelated to hyperparathyroidism. In this uncommon disease: hyperparathyroidism-jaw tumor (HPT-JT) syndrome, parathyroid tumor is frequently malignant and usually associated with nonendocrine malignancies (2). We report a case of a HPT-JT syndrome to focus on the differential diagnosis with brown tumors.
authors.affiliation: Department of Endocrinology and Diabetology, Mohammed VI University Medical Hospital of Marrakech, Medecine School of Marrakech, University Caddi Ayyad of Marrakech, Morocco.
authors.forename: Laila
authors.initials: L
authors.lastname: Ennazk
authors.affiliation: Department of Endocrinology and Diabetology, Mohammed VI University Medical Hospital of Marrakech, Medecine School of Marrakech, University Caddi Ayyad of Marrakech, Morocco.
authors.forename: Ghizlane
authors.initials: G
authors.lastname: El Mghari
authors.affiliation: Department of Endocrinology and Diabetology, Mohammed VI University Medical Hospital of Marrakech, Medecine School of Marrakech, University Caddi Ayyad of Marrakech, Morocco.
authors.forename: Nawal
authors.initials: N
authors.lastname: El Ansari
keywords: brown tumor; hyperparathyroidism-jaw tumor syndrome; ossifying fibroma; primary hyperparathyroidism