title: Noncontact speckle-based optical sensor for detection of glucose concentration using magneto-optic effect.
abstract: We experimentally verify a speckle-based technique for noncontact measurement of glucose concentration in the bloodstream. The final device is intended to be a single wristwatch-style device containing a laser, a camera, and an alternating current (ac) electromagnet generated by a solenoid. The experiments presented are performed in vitro as proof of the concept. When a glucose substance is inserted into a solenoid generating an ac magnetic field, it exhibits Faraday rotation, which affects the temporal changes of the secondary speckle pattern distributions. The temporal frequency resulting from the ac magnetic field was found to have a lock-in amplification role, which increased the observability of the relatively small magneto-optic effect. Experimental results to support the proposed concept are presented.
authors.affiliation: Bar-Ilan University, Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Ramat Gan 52900, Israel.
authors.forename: Nisan
authors.initials: N
authors.lastname: Ozana
authors.affiliation: Bar-Ilan University, Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Ramat Gan 52900, Israel.
authors.forename: Yevgeny
authors.initials: Y
authors.lastname: Beiderman
authors.affiliation: MS University of Baroda, Applied Physics Department, Faculty of Technology and Engineering, Optics Laboratory, Vadodara 390001, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Anand
authors.affiliation: University of Connecticut, Department of Electrical and Computer Engineering, Storrs, Connecticut 06269-4157, United States.
authors.forename: Baharam
authors.initials: B
authors.lastname: Javidi
authors.affiliation: ContinUse Biometrics Ltd., Tel-Aviv 6912209, Israel.
authors.forename: Sagi
authors.initials: S
authors.lastname: Polani
authors.affiliation: ContinUse Biometrics Ltd., Tel-Aviv 6912209, Israel.
authors.forename: Ariel
authors.initials: A
authors.lastname: Schwarz
authors.affiliation: Bar-Ilan University, Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Ramat Gan 52900, Israel.
authors.forename: Amir
authors.initials: A
authors.lastname: Shemer
authors.affiliation: Universitat de València, Departamento de Óptica, Burjassot 46100, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Garcia
authors.affiliation: Bar-Ilan University, Faculty of Engineering and the Institute of Nanotechnology and Advanced Materials, Ramat Gan 52900, Israel.
authors.forename: Zeev
authors.initials: Z
authors.lastname: Zalevsky
mesh_terms: D001774:Blood Chemical Analysis / Q000295:instrumentation / Q000379:methods*; D001786:Blood Glucose / Q000032:analysis*; D006801:Humans; D007834:Lasers; D008027:Light; D059346:Magnets; D055095:Optics and Photonics; D012399:Rotation
chemical_list: D001786:Blood Glucose