title: Male cytogenetic evaluation prior to assisted reproduction procedures performed in Mar del Plata, Argentina.
abstract: OBJECTIVE
  This paper aimed to estimate the frequency of occurrence and the types of chromosomal abnormalities found in 141 infertile men with abnormal semen parameters.
  
  
  METHODS
  the frequency and type of chromosomal abnormalities were determined with male mitotic karyotype analysis from peripheral blood through chromosome banding techniques before assisted reproduction procedures.
  
  
  RESULTS
  In this series of 141 infertile men, 19 (13%) had chromosomal anomalies and 35 (25%) had polymorphic variants. The main chromosome abnormalities were reciprocal translocations and marker chromosomes in mosaic.
  
  
  CONCLUSIONS
  These results stress the relevance of cytogenetic studies for infertile males as a diagnostic tool and a valuable input in genetic counseling.
authors.affiliation: Genetics Laboratory, Biology Department FCEyN, National University of Mar del Plata, Argentina.|CONICET - The National Scientific and Technical Research Council, Argentina.|Association of Human Genetics (AGHU) of Mar del Plata, Argentina.
authors.forename: María N
authors.initials: MN
authors.lastname: Poli
authors.affiliation: Association of Human Genetics (AGHU) of Mar del Plata, Argentina.
authors.forename: Lucía A López
authors.initials: LA
authors.lastname: Miranda
authors.affiliation: Association of Human Genetics (AGHU) of Mar del Plata, Argentina.
authors.forename: Eduardo Daniel
authors.initials: ED
authors.lastname: Gil
authors.affiliation: Association of Human Genetics (AGHU) of Mar del Plata, Argentina.
authors.forename: Germán Justo
authors.initials: GJ
authors.lastname: Zanier
authors.affiliation: Genetics Laboratory, Biology Department FCEyN, National University of Mar del Plata, Argentina.|CONICET - The National Scientific and Technical Research Council, Argentina.
authors.forename: Pedro Fernández
authors.initials: PF
authors.lastname: Iriarte
authors.affiliation: Association of Human Genetics (AGHU) of Mar del Plata, Argentina.
authors.forename: Justo H Mario
authors.initials: JH
authors.lastname: Zanier
authors.affiliation: FECUNDITAS - Reproductive Medicine associated to Buenos Aires University, Argentina.
authors.forename: Roberto
authors.initials: R
authors.lastname: Coco
mesh_terms: D001118:Argentina; D053713:Azoospermia / Q000453:epidemiology / Q000235:genetics; D002869:Chromosome Aberrations / Q000706:statistics & numerical data*; D015331:Cohort Studies; D005817:Genetic Counseling; D006801:Humans; D015994:Incidence; D059785:Karyotype; D007621:Karyotyping; D008297:Male; D009845:Oligospermia / Q000453:epidemiology / Q000235:genetics; D027724:Reproductive Techniques, Assisted
keywords: assisted reproduction technology; chromosomal anomalies; male infertility