title: Update in Hypertension Therapy.
abstract: Hypertension is the leading cause of early mortality in the world, and reduction of blood pressure can help to reduce that burden. There is an enormous and ever-expanding body of literature on hypertension, with a 2016 Medline search for hypertension retrieving more than 113,000 publications. Recent guidelines from major societies have been published, and often present conflicting recommendations based on the same data. Using a question-and-answer format, this article reviews some of the recent developments and opinions on management of blood pressure and provides practical suggestions for management in the clinical arena.
authors.affiliation: Department of Graduate Medical Education, Legacy Health, 1200 Northwest 23rd Avenue, Portland, OR 97210, USA. Electronic address: LMANKIN@LHS.ORG.
authors.forename: Leonard A
authors.initials: LA
authors.lastname: Mankin
mesh_terms: D001741:Black or African American; D057911:Angiotensin Receptor Antagonists / Q000627:therapeutic use; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D000959:Antihypertensive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001794:Blood Pressure; D002121:Calcium Channel Blockers / Q000627:therapeutic use; D003920:Diabetes Mellitus / Q000453:epidemiology; D004032:Diet; D004305:Dose-Response Relationship, Drug; D004359:Drug Therapy, Combination; D006073:Gout / Q000453:epidemiology; D054143:Heart Failure, Systolic / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000188:drug therapy* / Q000453:epidemiology; D008019:Life Style; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology; D049993:Sodium Chloride Symporter Inhibitors / Q000627:therapeutic use; D013148:Spironolactone / Q000627:therapeutic use
chemical_list: D057911:Angiotensin Receptor Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D000959:Antihypertensive Agents; D002121:Calcium Channel Blockers; D049993:Sodium Chloride Symporter Inhibitors; D013148:Spironolactone
keywords: Antihypertensives; Blood pressure; Blood pressure goals; Hypertension; SGLT-2 inhibitors; Spironolactone; Therapy