title: The effect of topical lidocaine on muscle artefacts in awake canine electroencephalogram recordings.
abstract: Muscle artefacts in electroencephalogram recording data interfere with diagnostic accuracy. Lidocaine may reduce these artefacts. The objective of this study was to determine the effect of topical lidocaine on muscle artefacts in unanesthetized canine electroencephalogram (EEG) recording data. Topical 4% lidocaine was applied to each electrode site for six treated dogs prior to subdermal wire electrode placement and compared against historical untreated controls. Twenty-minute recordings began 30 min after lidocaine application. Three epochs (early, middle, and end) were sampled from each recording and scored for muscle artefact incidence and severity by two blinded reviewers. No significant treatment effects on incidence and severity were found. Application of topical lidocaine does not appear to reduce the occurrence of muscle artefacts in canine EEG recordings.
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, Canada N1G 2W1.
authors.forename: Jordan
authors.initials: J
authors.lastname: Ward
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, Canada N1G 2W1. Electronic address: jamesf@uoguelph.ca.
authors.forename: Fiona
authors.initials: F
authors.lastname: James
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, ON, Canada N1G 2W1.
authors.forename: Gabrielle
authors.initials: G
authors.lastname: Monteith
mesh_terms: D000818:Animals; D016477:Artifacts; D004285:Dogs / Q000502:physiology*; D004569:Electroencephalography / Q000379:methods / Q000662:veterinary*; D005260:Female; D008012:Lidocaine / Q000494:pharmacology*; D018482:Muscle, Skeletal / Q000502:physiology*; D061567:Voltage-Gated Sodium Channel Blockers / Q000494:pharmacology*
chemical_list: D061567:Voltage-Gated Sodium Channel Blockers; D008012:Lidocaine
keywords: Canine; Electroencephalogram; Liposomal lidocaine; Muscle artefacts; Subdermal wire electrodes