title: Discovery of a gamma heavy chain disease in a patient followed-up for a lymphoplasma cell proliferative disorder.
abstract: Gamma-heavy chains disease is a rare disease, with very few cases described in the literature. It is characterized by the presence of a monoclonal gamma-heavy chain without associated light chain. Its prevalence and prognosis are unknown. We report here the accidental discovery of a case of gamma-heavy chain disease during a pancytopenia exploration, performed in the hospital, in a patient known since 2002 for a lymphoplasmacytic type lymphoma first localized in bone marrow.
authors.affiliation: Laboratoire de biochimie et de biologie moléculaire, Centre hospitalier régional universitaire Trousseau, Tours, France.
authors.forename: Camille
authors.initials: C
authors.lastname: Humeau
authors.affiliation: Service d'hématologie et thérapie cellulaire, Centre hospitalier régional universitaire Bretonneau, Tours, France.
authors.forename: Hélène
authors.initials: H
authors.lastname: Monjanel
authors.affiliation: Laboratoire de biochimie et de biologie moléculaire, Centre hospitalier régional universitaire Trousseau, Tours, France.
authors.forename: François
authors.initials: F
authors.lastname: Schellenberg
mesh_terms: D000369:Aged, 80 and over; D057210:Delayed Diagnosis; D006362:Heavy Chain Disease / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D008991:Monitoring, Physiologic; D008258:Waldenstrom Macroglobulinemia / Q000150:complications* / Q000175:diagnosis / Q000628:therapy
keywords: heavy chain disease; immunotyping