title: The potential of the second sight system bionic eye implant for partial sight restoration.
abstract: BACKGROUND
  Second Sight System bionic eye implant, a commercially available visual prosthesis developed by Second Sight Medical Products, has been implanted in over 125 patients with outer retinal dystrophies such as retinitis pigmentosa. The system has gained regulatory approval in both the USA and Europe, and aims to restore vision by electrical stimulation of the nerve cells of the inner retina.
  
  
  METHODS
  In this review, we present the safety profile of this implant from the international clinical trial and discuss the nature and levels of improvement in visual function achieved by patients implanted with the system. Expert commentary: Future developments for the system will be explored following the discussion of the current usefulness of the device, its limitation as and the areas in which further development is necessary.
authors.affiliation: a Vitreoretinal Research , Moorfields Eye Hospital NHS Foundation Trust , London , UK.|b Institute of Ophthalmology , University College London , London , UK.
authors.forename: Yvonne Hsu-Lin
authors.initials: YH
authors.lastname: Luo
authors.affiliation: a Vitreoretinal Research , Moorfields Eye Hospital NHS Foundation Trust , London , UK.
authors.forename: Eka
authors.initials: E
authors.lastname: Fukushige
authors.affiliation: a Vitreoretinal Research , Moorfields Eye Hospital NHS Foundation Trust , London , UK.|b Institute of Ophthalmology , University College London , London , UK.|c NIHR Biomedical Research Centre , Moorfields Eye Hospital NHS Foundation Trust , London , UK.
authors.forename: Lyndon
authors.initials: L
authors.lastname: Da Cruz
mesh_terms: D001701:Bionics; D002986:Clinical Trials as Topic; D006801:Humans; D016896:Treatment Outcome; D014785:Vision, Ocular / Q000502:physiology*; D014792:Visual Acuity; D057488:Visual Prosthesis / Q000009:adverse effects
keywords: Argus® II; Bionic eye; electrical stimulation of the inner retina; low vision; prosthetic vision; retinal implant; retinal prosthesis; retinitis pigmentosa; visual rehabilitation