title: Circadian Control of Antibacterial Immunity: Findings from Animal Models.
abstract: Most of the biological functions, including the immune system, are linked to circadian rhythms in living organisms. Changes occurring to biological parameters as the result of these circadian rhythms can therefore affect the outcome of a disease. For decades, model organisms have proven to be a great tool to understanding biological mechanisms such as circadian cycle and immunity. In this review, we created an inventory of the use of model organisms in order to decipher the relation between circadian rhythms and antibacterial immunity.
authors.affiliation: Centre National de la Recherche Scientifique UMR 7278, IRD198, Institut National de la Santé et de la Recherche Médicale U1095, Institut Hospitalier Universitaire Méditerranée-Infection, Aix-Marseille Université Marseille, France.
authors.forename: Landry L
authors.initials: LL
authors.lastname: Tsoumtsa
authors.affiliation: Centre National de la Recherche Scientifique UMR 7278, IRD198, Institut National de la Santé et de la Recherche Médicale U1095, Institut Hospitalier Universitaire Méditerranée-Infection, Aix-Marseille Université Marseille, France.
authors.forename: Cedric
authors.initials: C
authors.lastname: Torre
authors.affiliation: Centre National de la Recherche Scientifique UMR 7278, IRD198, Institut National de la Santé et de la Recherche Médicale U1095, Institut Hospitalier Universitaire Méditerranée-Infection, Aix-Marseille Université Marseille, France.
authors.forename: Eric
authors.initials: E
authors.lastname: Ghigo
mesh_terms: D000818:Animals; D001424:Bacterial Infections / Q000276:immunology* / Q000473:pathology; D056926:CLOCK Proteins / Q000235:genetics / Q000378:metabolism; D002940:Circadian Rhythm / Q000276:immunology*; D004330:Drosophila / Q000276:immunology; D029721:Drosophila Proteins / Q000378:metabolism; D006801:Humans; D051379:Mice; D023421:Models, Animal; D056950:Period Circadian Proteins / Q000378:metabolism; D051996:Transcription Factor RelA / Q000378:metabolism
chemical_list: D029721:Drosophila Proteins; C539040:PER protein, Drosophila; D056950:Period Circadian Proteins; C498144:Rela protein, mouse; D051996:Transcription Factor RelA; C096445:tim protein, Drosophila; D056926:CLOCK Proteins; C538944:Clock protein, mouse
keywords: antibacterial; bacteria; chrono-immunology; circadian; drosophila; mice