title: Intravital imaging technology reveals immune system dynamics in vivo.
abstract: Fluorescent 'intravital' imaging is a new research technique by which the interior of living tissues and organs (in living bodies, if possible) can be observed, revealing the kinetics of cell and molecular processes in real time. Recent technological innovations in optical equipment and fluorescence imaging techniques have enabled a variety of cellular phenomena in different tissues and organs to be characterized under completely native conditions. This shift from static to dynamic biology constitutes the beginning of a new era in biomedical sciences.
authors.affiliation: Department of Immunology and Cell Biology, Graduate School of Medicine and Frontier Biosciences, Osaka University, Osaka, Japan. Electronic address: mishii@icb.med.osaka-u.ac.jp.
authors.forename: Masaru
authors.initials: M
authors.lastname: Ishii
mesh_terms: D000818:Animals; D001853:Bone Marrow / Q000000981:diagnostic imaging; D001842:Bone and Bones / Q000000981:diagnostic imaging; D006801:Humans; D007107:Immune System / Q000000981:diagnostic imaging*; D000069416:Intravital Microscopy / Q000379:methods*
keywords: Cellular dynamics; Immune system; Inflammation; Intravital imaging; Multiphoton microscopy