title: Growing Kidney Tissue from Stem Cells: How Far from "Party Trick" to Medical Application?
abstract: The successful generation of kidney-like structures from human pluripotent stem cells, although slower to come than other tissue types, brings the hope of new therapies. While the demand for alternative treatments for kidney failure is acute, huge challenges remain to move these exciting but preliminary results toward clinical use.
authors.affiliation: Murdoch Childrens Research Institute, Flemington Road, Parkville 3052, Australia; Department of Pediatrics, Faculty of Medicine, Dentistry, and Health Sciences, University of Melbourne, Parkville 3052, Australia. Electronic address: melissa.little@mcri.edu.au.
authors.forename: Melissa H
authors.initials: MH
authors.lastname: Little
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D006801:Humans; D007668:Kidney / Q000196:embryology / Q000254:growth & development*; D009399:Nephrons / Q000166:cytology; D009940:Organoids / Q000166:cytology; D039904:Pluripotent Stem Cells; D012038:Regeneration; D013234:Stem Cells / Q000166:cytology*; D057170:Translational Research, Biomedical