title: Anomalous origin of the left coronary artery from the pulmonary artery in children: diagnostic use of multidetector computed tomography.
abstract: BACKGROUND
  Anomalous origin of the left coronary artery from the pulmonary artery is a rare congenital anomaly. It is important to demonstrate the anomalous origin of the left coronary artery and its course before surgery.
  
  
  OBJECTIVE
  To explore the clinical diagnostic use of multidetector CT coronary angiography in detecting anomalous origin of the left coronary artery from the pulmonary artery in children.
  
  
  METHODS
  Nine children (2 boys, 7 girls) ages 2 months to 9 years with surgically confirmed anomalous origin of the left coronary artery from the pulmonary artery were studied. Clinical data, transthoracic echocardiography and CT coronary angiography images were retrospectively analyzed.
  
  
  RESULTS
  Transthoracic echocardiography correctly diagnosed anomalous origin of the left coronary artery from the pulmonary artery in 7 of 9 patients (95% CI: 40-97%). CT coronary angiography revealed the anomalous origin of the left coronary artery in all children (95% CI: 66-100%). In a 4-year-old girl and a 9-year-old girl, CT coronary angiography showed dilation of the right coronary artery and collateral circulation between the right and the left coronary arteries.
  
  
  CONCLUSIONS
  CT coronary angiography is a useful method to show the anomalous origin of the coronary artery in children with anomalous origin of the left coronary artery from the pulmonary artery, especially for patients in whom origin of the left coronary artery cannot be detected by transthoracic echocardiography.
authors.affiliation: Department of Radiology, Children's Hospital of Fudan University, 399 Wanyuan St., Shanghai, 201102, China.
authors.forename: Quanli
authors.initials: Q
authors.lastname: Shen
authors.affiliation: Department of Radiology, Children's Hospital of Fudan University, 399 Wanyuan St., Shanghai, 201102, China.
authors.forename: Qiong
authors.initials: Q
authors.lastname: Yao
authors.affiliation: Department of Radiology, Children's Hospital of Fudan University, 399 Wanyuan St., Shanghai, 201102, China. huxihong777@sina.com.
authors.forename: Xihong
authors.initials: X
authors.lastname: Hu
mesh_terms: D002648:Child; D002675:Child, Preschool; D017023:Coronary Angiography; D003330:Coronary Vessel Anomalies / Q000000981:diagnostic imaging* / Q000601:surgery; D004452:Echocardiography; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D061330:Multidetector Computed Tomography; D011651:Pulmonary Artery / Q000002:abnormalities*; D012189:Retrospective Studies
keywords: Children; Computed tomography; Congenital anomaly; Coronary angiography; Coronary artery