title: The functional brain connectome of the child and autism spectrum disorders.
abstract: Brain connectomics is a relatively new field of research that maps the brain's large-scale structural and functional networks at rest. The connectome of the human brain develops progressively from early infancy to late adolescence, and this review describes the theory behind the concept and its applicability to studying the development and dynamics of brain networks through graph theoretical metrics. We also describe how the brain connectome concept could further our understanding of autism spectrum disorders (ASD) CONCLUSION: Further research into the functional child brain connectome concept could enhance our understanding of atypical brain connectivity patterns presumed to be linked to ASD.
authors.affiliation: Laboratory for the Psychology of Child Development and Education (LaPsyDÉ), CNRS UMR 8240, Sorbonne Paris Cité, GIP Cyceron, Université de Caen Normandie, Université Paris Descartes, Paris, France.
authors.forename: Katell
authors.initials: K
authors.lastname: Mevel
authors.affiliation: Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.
authors.forename: Peter
authors.initials: P
authors.lastname: Fransson
mesh_terms: D000293:Adolescent; D000067877:Autism Spectrum Disorder / Q000000981:diagnostic imaging*; D001921:Brain / Q000254:growth & development*; D002648:Child; D002657:Child Development; D002675:Child, Preschool; D063132:Connectome; D006801:Humans; D007858:Learning; D008279:Magnetic Resonance Imaging
keywords: Autism spectrum disorders; Child brain connectome; Connectivity; Functional magnetic resonance imaging; Resting state