title: An acute gastroenteritis outbreak caused by GII.17 norovirus in Jiangsu Province, China.
abstract: Noroviruses are a common cause of acute gastroenteritis around the world; however, reports of outbreaks caused by GII.17 norovirus are rare. An outbreak caused by GII.17 norovirus in a senior high school in Wuxi, Jiangsu Province, China is reported here. An epidemiological investigation, pathogen detection, and case-control study were performed. Epidemiological data combined with the epidemic curve indicated that this outbreak was a point source type initially, followed by secondary transmission. The first case was identified as most likely the source of the outbreak. Risk analysis showed exposure to patients and sharing a communal water cooler to be associated with the spread of infection. Sequence analysis of GII-positive samples confirmed that the norovirus GII.17 variant was the etiological agent of this outbreak.
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Shi
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Wei-Hong
authors.initials: WH
authors.lastname: Feng
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Shi
authors.affiliation: Jiangsu Center for Disease Control and Prevention, Nanjing, Jiangsu, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Ai
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Hong-Xia
authors.initials: HX
authors.lastname: Guan
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Sha
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Geng
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Jun
authors.initials: J
authors.lastname: Mei
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China.
authors.forename: Shan-Hui
authors.initials: SH
authors.lastname: Chen
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China. Electronic address: wxcdcxy@163.com.
authors.forename: Yong
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: Wuxi Center for Disease Control and Prevention, Wuxi, Jiangsu 214023, China. Electronic address: wxcdcjkb@sina.cn.
authors.forename: Yan-Hua
authors.initials: YH
authors.lastname: Qian
mesh_terms: D017250:Caliciviridae Infections / Q000453:epidemiology / Q000821:virology*; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D004196:Disease Outbreaks; D058872:Epidemics; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology*; D005838:Genotype; D006801:Humans; D029322:Norovirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification* / Q000502:physiology; D010802:Phylogeny
keywords: Disease outbreak; Molecular epidemiology; Noroviruses