title: BILATERAL COATS REACTION IN BANNAYAN-ZONANA SYNDROME: A SINGLE CASE REPORT.
abstract: OBJECTIVE
  To report the clinical features of bilateral Coats reaction in a patient with Bannayan-Zonana syndrome.
  
  
  METHODS
  The clinical course and retinal manifestations of a 21-year-old patient with Bannayan-Zonana syndrome and bilateral Coats reaction were studied. Retinal manifestations were documented with clinical examination, ultrawide-field color imaging, and ultrawide-field fluorescein angiography.
  
  
  RESULTS
  Best-corrected visual acuities were 20/25 OD and 20/25 OS. Anterior segment examinations were normal bilaterally. The inferotemporal quadrant of the left retina demonstrated retinal telangiectasias, exudation, and a neurosensory retinal detachment extending to the mid-periphery. Fluorescein angiography demonstrated bilateral peripheral nonperfusion and vascular staining. An epiretinal membrane also involved the left macula.
  
  
  CONCLUSIONS
  Bannayan-Zonana syndrome is an autosomal-dominant, hamartomatous disease characterized by a mutation spectrum that involves genes responsible for vascular development. Retinal vascular abnormalities and exudation can be a manifestation of this syndrome.
authors.affiliation: *Vitreous-Retina-Macula Consultants of New York, New York, New York; †The LuEsther T. Mertz Retinal Research Center, New York, New York; ‡Department of Ophthalmology, New York University School of Medicine, New York, New York; §Department of Physiology and Pharmacology, Centre for Ophthalmology and Visual Sciences, Lions Eye Institute, University of Western Australia, Perth, Australia; and ¶Department of Ophthalmology, New York-Presbyterian, New York, New York.
authors.forename: Meredith R
authors.initials: MR
authors.lastname: Klifto
authors.forename: Chandrakumar
authors.initials: C
authors.lastname: Balaratnasingam
authors.forename: Harold H
authors.initials: HH
authors.lastname: Weissman
authors.forename: Lawrence A
authors.initials: LA
authors.lastname: Yannuzzi
mesh_terms: D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D006223:Hamartoma Syndrome, Multiple / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D008297:Male; D058456:Retinal Telangiectasis / Q000175:diagnosis / Q000209:etiology*; D014792:Visual Acuity; D055815:Young Adult