title: A computational platform for continuous seizure anticipation, monitoring and clinical evaluation.
abstract: The development of platforms that are able to continuously monitor and handle epileptic seizures in a non invasive manner is of great importance as they would improve the quality of life of drug resistant epileptic patients. In this work, a device and a computational platform is presented for acquiring low noise electroencephalographic signals, for the detection/prediction of epileptic seizures and the storage of ictal activity in an electronic personal health record. In order to develop this platform, a systematic clinical protocol was established including a number of drug resistant children from the University Hospital of Heraklion. Dry electrodes with innovative micro-spike design were proposed in order to increase the signal to noise ratio of the recorded EEG signals. A wearable low cost platform and its corresponding wireless communication protocol was developed focus on minimizing the interference with the patient's body. A computational subsystem with advanced algorithms provides detection/anticipation of upcoming seizure activity and aims to protect the patient from an accident due to a seizure or to improve his/her social life. Finally, the seizure activity information is stored in an electronic health record for further clinical evaluation.
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Computer Science, Heraklion, Crete, Greece.
authors.forename: Giorgos
authors.initials: G
authors.lastname: Giannakakis
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Computer Science, Heraklion, Crete, Greece.
authors.forename: Matthew
authors.initials: M
authors.lastname: Pediaditis
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Electronic Structure and Laser, Heraklion, Crete, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Stavrinidis
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Electronic Structure and Laser, Heraklion, Crete, Greece.
authors.forename: George
authors.initials: G
authors.lastname: Konstantinidis
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Computer Science, Heraklion, Crete, Greece.
authors.forename: Vangelis
authors.initials: V
authors.lastname: Kritsotakis
authors.affiliation: Computer & Information Engineering Department, Technological Education Institute of Western Greece, Antirio, Greece.
authors.forename: Vasilis
authors.initials: V
authors.lastname: Tsakanikas
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Electronic Structure and Laser, Heraklion, Crete, Greece.
authors.forename: Michael
authors.initials: M
authors.lastname: Ligerakis
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Computer Science, Heraklion, Crete, Greece.
authors.forename: Vangelis
authors.initials: V
authors.lastname: Sakkalis
authors.affiliation: University of Crete, Faculty of Medicine, Heraklion, Greece.
authors.forename: Pelagia
authors.initials: P
authors.lastname: Vorgia
authors.affiliation: Foundation for Research and Technology - Hellas, Institute of Computer Science, Heraklion, Crete, Greece.
authors.forename: Manolis
authors.initials: M
authors.lastname: Tsiknakis
mesh_terms: D000465:Algorithms; D004566:Electrodes; D004569:Electroencephalography / Q000295:instrumentation* / Q000379:methods; D057286:Electronic Health Records; D004827:Epilepsy / Q000175:diagnosis* / Q000473:pathology; D006801:Humans; D018670:Monitoring, Ambulatory / Q000295:instrumentation / Q000379:methods; D012640:Seizures / Q000175:diagnosis* / Q000473:pathology; D000076251:Wearable Electronic Devices