title: Chemiluminescent lateral-flow immunoassays by using in-situ synthesis of CdS NW photosensor.
abstract: A hypersensitive CdS nanowire (NW) photosensor was fabricated by an in-situ synthesis process that involved the direct synthesis of CdS NWs on an interdigitated electrode (IDE). Analysis of the photoresponse properties showed that the newly synthesized photosensor had enhanced sensitivity and a highly reproducible photoresponse compared to photosensors prepared from CdS NW suspensions. The NW photosensor was applied to measure the chemiluminescence of luminol, and the sensitivity was compared to a commercial photosensing system. Finally, the feasibility of the CdS NW photosensor for the application to the medical diagnosis of the human hepatitis B surface antigen (hHBsAg) was demonstrated using a lateral-flow immunoassay with a chemiluminescent signal band.
authors.affiliation: Department of Materials Sciences and Engineering, Yonsei University, 50 Yonsei-Ro, Seo-dae-mun-gu, Seoul, 120-749, Republic of Korea.
authors.forename: Byoung-Gi
authors.initials: BG
authors.lastname: An
authors.affiliation: Department of Materials Sciences and Engineering, Yonsei University, 50 Yonsei-Ro, Seo-dae-mun-gu, Seoul, 120-749, Republic of Korea.
authors.forename: Hong-Rae
authors.initials: HR
authors.lastname: Kim
authors.affiliation: Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
authors.forename: Min-Jung
authors.initials: MJ
authors.lastname: Kang
authors.affiliation: Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
authors.forename: Jae-Gwan
authors.initials: JG
authors.lastname: Park
authors.affiliation: Department of Materials Sciences and Engineering, Yonsei University, 50 Yonsei-Ro, Seo-dae-mun-gu, Seoul, 120-749, Republic of Korea.
authors.forename: Young Wook
authors.initials: YW
authors.lastname: Chang
authors.affiliation: Department of Materials Sciences and Engineering, Yonsei University, 50 Yonsei-Ro, Seo-dae-mun-gu, Seoul, 120-749, Republic of Korea. Electronic address: jcpyun@yonsei.ac.kr.
authors.forename: Jae-Chul
authors.initials: JC
authors.lastname: Pyun
mesh_terms: D019187:Cadmium Compounds / Q000737:chemistry*; D006514:Hepatitis B Surface Antigens / Q000032:analysis; D007118:Immunoassay / Q000379:methods*; D008027:Light; D057230:Limit of Detection; D049449:Luminescence; D008165:Luminol / Q000737:chemistry*; D053770:Nanowires; D015203:Reproducibility of Results; D018036:Selenium Compounds / Q000737:chemistry*
chemical_list: D019187:Cadmium Compounds; D006514:Hepatitis B Surface Antigens; D018036:Selenium Compounds; D008165:Luminol; C058667:cadmium selenide
keywords: CdS; Chemiluminescence; Interdigitated electrode; Nanowire; Photosensor