title: [Assessment of sentinel lymph node biopsy in patients receiving neoadjuvant chemotherapy in breast cancer: before or after?].
abstract: The main goal of preoperative chemotherapy is to reduce the size of the tumor and allow conservative treatment. Neoadjuvant treatment can affect axillary status with a downstaging in one third of the cases. For these patients, the benefit of axillary node dissection is questioned and the sentinel node biopsy (SLNB) seems to be a relevant option. However, the timing of performing SLNB is still debated especially for clinical negative patients with negative axillary ultrasound before preoperative chemotherapy. For axillary positive nodes proved by biopsy/cytology before preoperative chemotherapy, SLNB can be an option if there is a good clinical and radiological response.
authors.affiliation: Département de chirurgie oncologique, Centre de lutte contre le cancer Georges-François Leclerc (CGFL), 1, rue du Professeur-Marion, 21000 Dijon, France; UFR des sciences de santé, université de Bourgogne, 7, boulevard Jeanne-d'Arc, 21000 Dijon, France. Electronic address: ccoutant@cgfl.fr.
authors.forename: C
authors.initials: C
authors.lastname: Coutant
authors.affiliation: Département de chirurgie oncologique, Centre de lutte contre le cancer Georges-François Leclerc (CGFL), 1, rue du Professeur-Marion, 21000 Dijon, France; UFR des sciences de santé, université de Bourgogne, 7, boulevard Jeanne-d'Arc, 21000 Dijon, France.
authors.forename: C
authors.initials: C
authors.lastname: Jankowski
authors.affiliation: Département de chirurgie oncologique, Centre de lutte contre le cancer Georges-François Leclerc (CGFL), 1, rue du Professeur-Marion, 21000 Dijon, France.
authors.forename: H
authors.initials: H
authors.lastname: Portha
authors.affiliation: Pôle de chirurgie oncologique générale, gynécologique et mammaire, centre Antoine-Lacassagne, 33, avenue de Valombrose, 06189 Nice cedex 2, France.
authors.forename: E
authors.initials: E
authors.lastname: Barranger
mesh_terms: D000970:Antineoplastic Agents / Q000008:administration & dosage; D001365:Axilla; D001943:Breast Neoplasms / Q000188:drug therapy / Q000473:pathology*; D005260:Female; D006801:Humans; D008197:Lymph Node Excision; D020360:Neoadjuvant Therapy; D009367:Neoplasm Staging; D000071036:Sentinel Lymph Node / Q000473:pathology; D021701:Sentinel Lymph Node Biopsy; D013997:Time Factors
chemical_list: D000970:Antineoplastic Agents
keywords: Breast cancer; Cancers du sein; Chimiothérapie néoadjuvante; Ganglion sentinelle; Preoperative chemotherapy; Sentinel lymph node