title: Sequence-Dependent Photocurrent Generation through Long-Distance Excess-Electron Transfer in DNA.
abstract: Given its well-ordered continuous π stacking of nucleobases, DNA has been considered as a biomaterial for charge transfer in biosensors. For cathodic photocurrent generation resulting from hole transfer in DNA, sensitivity to DNA structure and base-pair stacking has been confirmed. However, such information has not been provided for anodic photocurrent generation resulting from excess-electron transfer in DNA. In the present study, we measured the anodic photocurrent of a DNA-modified Au electrode. Our results demonstrate long-distance excess-electron transfer in DNA, which is dominated by a hopping mechanism, and the photocurrent generation is sequence dependent.
authors.affiliation: The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Mihogaoka 8-1, Ibaraki, Osaka, 567-0047, Japan.
authors.forename: Shih-Hsun
authors.initials: SH
authors.lastname: Lin
authors.affiliation: The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Mihogaoka 8-1, Ibaraki, Osaka, 567-0047, Japan. fuji@sanken.osaka-u.ac.jp.
authors.forename: Mamoru
authors.initials: M
authors.lastname: Fujitsuka
authors.affiliation: The Institute of Scientific and Industrial Research (SANKEN), Osaka University, Mihogaoka 8-1, Ibaraki, Osaka, 567-0047, Japan. majima@sanken.osaka-u.ac.jp.
authors.forename: Tetsuro
authors.initials: T
authors.lastname: Majima
mesh_terms: D001483:Base Sequence; D004247:DNA / Q000737:chemistry*; D055664:Electrochemical Techniques; D004566:Electrodes; D004579:Electron Transport; D006046:Gold / Q000737:chemistry; D010084:Oxidation-Reduction; D011789:Quantum Theory
chemical_list: D006046:Gold; D004247:DNA
keywords: DNA; electrochemistry; electron transfer; photochemistry; thin films