title: [COMPARATIVE CHARACTERISTIC OF VARIOUS METHODS OF SIMULATION OF BILIARY PERITONITIS IN EXPERIMENT].
abstract: In experiment on rabbits a comparative analysis of various methods of a biliary peritonitis simulation was conducted. In 6 animals a biliary peritonitis was simulated, using perforation of a gallbladder, local serous-fibrinous peritonitis have occurred in 50% of them. In 7 animals biliary peritonitis was simulated, applying intraabdominal injection of medical sterile bile in a 5-40 ml volume. Diffuse peritonitis with exudates and stratification of fibrin was absent. Most effective method have appeared that, when intraabdominal injection of bile was done together with E. coli culture in the rate of 0.33 microbal bodies McF (1.0 x 10(8) CFU/ml) on 1 kg of the animal body mass. Diffuse biliary peritonitis have occurred in all 23 animals, including serous-fibrinous one--in 17 (76%), and purulent-fibrinous--in 6 (24%).
authors.forename: M Yu
authors.initials: MY
authors.lastname: Nichitaylo
authors.forename: Yu O
authors.initials: YO
authors.lastname: Furmanov
authors.forename: A I
authors.initials: AI
authors.lastname: Gutsulyak
authors.forename: I M
authors.initials: IM
authors.lastname: Savytska
authors.forename: M S
authors.initials: MS
authors.lastname: Zagriychuk
authors.forename: A V
authors.initials: AV
authors.lastname: Goman
mesh_terms: D000818:Animals; D001646:Bile / Q000737:chemistry*; D015169:Colony Count, Microbial; D004195:Disease Models, Animal; D004926:Escherichia coli / Q000254:growth & development / Q000472:pathogenicity; D004927:Escherichia coli Infections / Q000382:microbiology / Q000473:pathology*; D005122:Exudates and Transudates / Q000378:metabolism; D005337:Fibrin / Q000378:metabolism; D006801:Humans; D010538:Peritonitis / Q000382:microbiology / Q000473:pathology*; D011817:Rabbits; D012720:Severity of Illness Index
chemical_list: D005337:Fibrin