title: The utilization of spirocyclic scaffolds in novel drug discovery.
authors.affiliation: a Vitae Pharmaceuticals , Fort Washington , PA , USA.
authors.forename: Ya-Jun
authors.initials: YJ
authors.lastname: Zheng
authors.affiliation: a Vitae Pharmaceuticals , Fort Washington , PA , USA.
authors.forename: Colin M
authors.initials: CM
authors.lastname: Tice
mesh_terms: D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006801:Humans; D013141:Spiro Compounds / Q000138:chemical synthesis* / Q000737:chemistry
chemical_list: D006571:Heterocyclic Compounds; D013141:Spiro Compounds
keywords: Drug discovery; spirocycles; spirocyclic scaffolds; structure-based drug design