title: Correlation between anterior chamber characteristics and laser flare photometry immediately after femtosecond laser treatment before phacoemulsification.
abstract: PurposeTo assess the anterior chamber (AC) characteristics and its correlation to laser flare photometry immediately after femtosecond laser-assisted capsulotomy and photodisruption.Patients and methodsThe study included 97 cataract eyes (n=97, mean age 68.6 years) undergoing femtosecond laser-assisted cataract surgery (FLACS). Three cohorts were analysed relating to the flare photometry directly post femtosecond laser treatment (flare <100 n=28, 69.6±7 years; flare 100-249 n=47, 67.7±8 years; flare >249 photon counts per ms cohort n=22, 68.5±10 years). Flare photometry (KOWA FM-700), corneal topography (Oculus Pentacam, Germany: AC depth, volume, angle, pachymetry), axial length, pupil diameter, and endothelial cells were assessed before FLACS, immediately after femtosecond laser treatment and 1 day postoperative (LenSx Alcon, USA). Statistical data were analysed by SPSS v19.0, Inc.ResultsThe AC depth, AC volume, AC angle, central and thinnest corneal thickness showed a significant difference between flare <100 vs flare 100-249 10 min post femtosecond laser procedure (P=0.002, P=0.023, P=0.007, P=0.003, P=0.011, respectively). The AC depth, AC volume, and AC angle were significantly larger (P=0.001, P=0.007, P=0.003, respectively) in the flare <100 vs flare >249 cohort 10 min post femtosecond laser treatment.ConclusionsA flat AC, low AC volume, and a narrow AC angle were parameters associated with higher intraocular inflammation. These criteria could be used for patient selection in FLACS to reduce postoperative intraocular inflammation.
authors.affiliation: Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Pahlitzsch
authors.affiliation: Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: N
authors.initials: N
authors.lastname: Torun
authors.affiliation: Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: M L
authors.initials: ML
authors.lastname: Pahlitzsch
authors.affiliation: Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: M K J
authors.initials: MK
authors.lastname: Klamann
authors.affiliation: Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Gonnermann
authors.affiliation: Department of Ophthalmology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
authors.forename: E
authors.initials: E
authors.lastname: Bertelmann
authors.affiliation: Augenklinik am Wittenbergplatz, Berlin, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Pahlitzsch
mesh_terms: D000368:Aged; D000867:Anterior Chamber / Q000378:metabolism / Q000473:pathology*; D018916:Blood-Aqueous Barrier / Q000502:physiology; D019923:Capsulorhexis; D002387:Cataract Extraction / Q000379:methods*; D005136:Eye Proteins / Q000378:metabolism; D006801:Humans; D053685:Laser Therapy / Q000379:methods*; D010783:Photometry / Q000379:methods*; D017785:Photons; D010865:Pilot Projects; D011446:Prospective Studies
chemical_list: D005136:Eye Proteins