title: Rhobupcyanoside B, A new cyanoside from Rhodiola bupleuroides.
abstract: One new cyanoside, rhobupcyanoside B (1), together with 7 known ones, was isolated from the 70% ethanol extract of the roots and rhizomes of Rhodiola bupleuroides. Their structures were determined by spectroscopic methods, including 2D NMR techniques. Compound 1 was evaluated for its inhibitory activity against α-glucosidase with IC50 value of 278.28 ± 0.55 μM by comparing with the positive control (acarbose) at 210.40 ± 0.32 μM.
authors.affiliation: a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education , College of Pharmaceutical Sciences, Southwest University , Chongqing 400715 , China.
authors.forename: Hong
authors.initials: H
authors.lastname: Wang
authors.affiliation: a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education , College of Pharmaceutical Sciences, Southwest University , Chongqing 400715 , China.
authors.forename: Li
authors.initials: L
authors.lastname: Dong
authors.affiliation: a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education , College of Pharmaceutical Sciences, Southwest University , Chongqing 400715 , China.
authors.forename: Jing-Qiu
authors.initials: JQ
authors.lastname: Ge
authors.affiliation: a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education , College of Pharmaceutical Sciences, Southwest University , Chongqing 400715 , China.
authors.forename: Li-Na
authors.initials: LN
authors.lastname: Deng
authors.affiliation: b Tibetan Collaborative Innovation Center of Agricultural and Animal Husbandry Resources, TAAHC-SWU Medicinal Plant R&D Center , Agriculture and Animal Husbandry College, Tibet University , Nyingchi 860000 , China.
authors.forename: Xiao-Zhong
authors.initials: XZ
authors.lastname: Lan
authors.affiliation: c TAAHC-SWU Medicinal Plant R&D Center, School of Life Sciences , Southwest University , Chongqing 400715 , China.
authors.forename: Zhi-Hua
authors.initials: ZH
authors.lastname: Liao
authors.affiliation: a Key Laboratory of Luminescent and Real-Time Analytical Chemistry (Southwest University), Ministry of Education , College of Pharmaceutical Sciences, Southwest University , Chongqing 400715 , China.
authors.forename: Min
authors.initials: M
authors.lastname: Chen
mesh_terms: D065089:Glycoside Hydrolase Inhibitors / Q000737:chemistry; D006027:Glycosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D020128:Inhibitory Concentration 50; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018517:Plant Roots / Q000737:chemistry; D029771:Rhodiola / Q000737:chemistry*; D000520:alpha-Glucosidases / Q000187:drug effects*
chemical_list: D065089:Glycoside Hydrolase Inhibitors; D006027:Glycosides; C000613653:rhobupcyanoside B; D000520:alpha-Glucosidases
keywords: Rhodiola bupleuroides; cyanoside; rhobupcyanoside B; α-glucosidase inhibitory activity