title: Evaluation of Lung Radiofrequency Ablation With Dual-Energy Computed Tomography: Analysis of Tumor Composition and Lung Perfusion.
abstract: OBJECTIVE
  The aim of this study was to evaluate radiofrequency ablation (RFA) of lung tumors with dual-energy computed tomography while focusing on tumor composition and lung perfusion.
  
  
  METHODS
  The 36 tumors in 25 patients were included. Dual-energy computed tomography was performed before RFA and at 2 days and 1, 3, and 6 months thereafter. The effective atomic number (Zeff) of the tumors before RFA was compared with the Zeff at each follow-up using the paired t test. Lung perfusion was evaluated by iodine map images. When decreased perfusion was suspected after RFA, lung perfusion scintigraphy was performed.
  
  
  RESULTS
  The mean Zeff of the tumors significantly (P < 0.001) decreased at each follow-up, compared with that before RFA. Lung perfusion in the parenchyma peripheral to the tumors appeared to decrease at 2 days in 9 tumors, which was confirmed by scintigraphy in 7 tumors.
  
  
  CONCLUSIONS
  Dual-energy computed tomography was useful by providing additional information on tumor composition and lung perfusion.
authors.affiliation: From the Department of Radiology, Okayama University Medical School, Okayama, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Tomita
authors.forename: Takao
authors.initials: T
authors.lastname: Hiraki
authors.forename: Hideo
authors.initials: H
authors.lastname: Gobara
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Fujiwara
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Iguchi
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Matsui
authors.forename: Susumu
authors.initials: S
authors.lastname: Kanazawa
mesh_terms: D000328:Adult; D000368:Aged; D001783:Blood Flow Velocity; D017115:Catheter Ablation; D000072226:Computed Tomography Angiography / Q000379:methods; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000517:prevention & control; D015900:Radiography, Dual-Energy Scanned Projection / Q000379:methods*; D016896:Treatment Outcome