title: What factors may influence epidemiological situation of tuberculosis in Poland and in the world?
abstract: The authors present the review of factors influencing epidemiological situation of tuberculosis in Poland and in the world. The groups of increased risk of tuberculosis, and clinical conditions predisposing to activation of latent tuberculosis infection (LTBI) such as HIV, uremia, diabetes mellitus, transplantation of organs, treatment with glucocorticosteroids and with antibodies to TNF and to its receptors, were presented. The higher prevalence and worse prognosis of tuberculosis in elderly people was emphasised. The methods of LTBI recognition, according to recent recommendations, with special consideration to patients in immunosupression, were shown. Methods of treatment to prevent LTBI activation, according to WHO experts, were also presented. All data were discussed in relation to the actual epidemiological situation of tuberculosis in Poland.
authors.forename: Ewa
authors.initials: E
authors.lastname: Rowińska-Zakrzewska
authors.forename: Maria
authors.initials: M
authors.lastname: Korzeniewska-Koseła
authors.forename: Ewa
authors.initials: E
authors.lastname: Augustynowicz-Kopeć
authors.affiliation: I Department Lung Diseases, National Tuberculosis and Lung Diseases Research Institute. monika.szturmowicz@gmail.com.
authors.forename: Monika
authors.initials: M
authors.lastname: Szturmowicz
mesh_terms: D000367:Age Factors; D000368:Aged; D048909:Diabetes Complications; D004198:Disease Susceptibility; D005260:Female; D014943:Global Health; D015658:HIV Infections / Q000150:complications / Q000382:microbiology; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects; D055985:Latent Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology; D008297:Male; D011044:Poland / Q000453:epidemiology; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D014374:Tuberculin Test; D014376:Tuberculosis / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology* / Q000276:immunology
keywords: diagnosis; epidemiology; immunology; latent tuberculosis infection; risk groups; treatment; tuberculosis