title: [Bronchoscopic treatments for COPD].
abstract: Several non-surgical and minimally invasive bronchoscopic interventions, such as bronchoscopic lung volume reduction (BLVR) techniques, have been developed to treat patients with severe chronic obstructive pulmonary disease (COPD). BLVR has been studied for treatment in severe COPD patients with emphysema. BLVR with one-way endobronchial valves is reported to be effective for patients with a heterogeneous emphysema distribution and without inter-lobar collateral ventilation. For the patients with collateral ventilation, and for the patients with homogeneous emphysema, BLVR with lung volume reduction coil has shown promising results. Targeted lung denervation(TLD) is a novel bronchoscopic intervention based on ablation of parasympathetic nerves surrounding the main bronchi. TLD seems to be effective for COPD with chronic bronchitis phenotype. This review gives a general overview of BLVR with one-way valve and lung volume reduction coil, and TLD.
authors.forename: Masamichi
authors.initials: M
authors.lastname: Mineshita
authors.forename: Takeo
authors.initials: T
authors.lastname: Inoue
authors.forename: Teruomi
authors.initials: T
authors.lastname: Miyazawa
mesh_terms: D001999:Bronchoscopy / Q000379:methods*; D003714:Denervation / Q000379:methods; D006801:Humans; D008168:Lung / Q000294:innervation; D011013:Pneumonectomy / Q000379:methods*; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications / Q000601:surgery*; D011656:Pulmonary Emphysema / Q000209:etiology / Q000601:surgery