title: A new composite scaffold of bioactive glass nanoparticles/graphene: Synchronous improvements of cytocompatibility and mechanical property.
abstract: This study presents a simple method of synthesizing bioactive glass nanoparticles/graphene nanosheets composite (BGs/GNS) scaffolds using the sol-gel and mold-compressing strategies. Characterizations of BGs/GNS scaffold revealed that BGs with an average diameter of 28.75nm were densely anchored onto both sides of GNS. When the mass ratio of BGs to graphene oxide was set as 10, this scaffold showed better cytocompatibility and higher osseointegration ability with surrounding tissues than the other scaffolds. The introduction of GNS also significantly enhanced the hardness and Young's modulus of BGs. Given the excellent performance of this scaffold, it has potential applications in bone regeneration and implantation.
authors.affiliation: School of Stomatology, Lanzhou University, Lanzhou 730000, PR China. Electronic address: zjfan@lzu.edu.cn.
authors.forename: Zengjie
authors.initials: Z
authors.lastname: Fan
authors.affiliation: State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, PR China.
authors.forename: Jinqing
authors.initials: J
authors.lastname: Wang
authors.affiliation: Liaocheng People's Hospital, Medical school of Liaocheng University, Shandong 252000, PR China.
authors.forename: Fengzhen
authors.initials: F
authors.lastname: Liu
authors.affiliation: Institute of Sensing Technology, Gansu Academy of Sciences, Lanzhou 730000, PR China.
authors.forename: Yingying
authors.initials: Y
authors.lastname: Nie
authors.affiliation: School of Stomatology, Lanzhou University, Lanzhou 730000, PR China.
authors.forename: Liling
authors.initials: L
authors.lastname: Ren
authors.affiliation: School of Stomatology, Lanzhou University, Lanzhou 730000, PR China. Electronic address: liubkq@lzu.edu.cn.
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry; D017886:Durapatite / Q000737:chemistry; D005898:Glass; D006108:Graphite / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D001672:Biocompatible Materials; D006108:Graphite; D017886:Durapatite
keywords: Bioactive glass; Graphene; Hydroxyapatite; Mechanical property; Scaffold