title: Early diagnosis of post-varicella necrotising fasciitis: A medical and surgical emergency.
abstract: Necrotising fasciitis (NF) is an extremely rare complication of a rather common paediatric viral exanthem varicella. Delayed diagnosis and treatment can lead to significant morbidity and mortality. Laboratory risk indicator of NF score aids in early clinical diagnosis in suspected cases of post-varicella NF thus enabling timely intervention. Surgery delayed for more than 24 hours, is an independent risk factor for death. Surgical debridement with good antibiotic coverage is the definitive treatment for NF.
authors.affiliation: Department of Paediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
authors.forename: Rose
authors.initials: R
authors.lastname: Xavier
authors.affiliation: Department of Paediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
authors.forename: Bobby
authors.initials: B
authors.lastname: Abraham
authors.affiliation: Department of Paediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
authors.forename: Vinod Jacob
authors.initials: VJ
authors.lastname: Cherian
authors.affiliation: Department of Paediatrics, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India.
authors.forename: Jobin I
authors.initials: JI
authors.lastname: Joseph
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002481:Cellulitis / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D002644:Chickenpox / Q000150:complications*; D002675:Child, Preschool; D003646:Debridement; D042241:Early Diagnosis; D019115:Fasciitis, Necrotizing / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000601:surgery*; D006801:Humans; D008297:Male; D012307:Risk Factors
chemical_list: D000900:Anti-Bacterial Agents