title: Chronic Thromboembolic Pulmonary Hypertension Associated with Chronic Inflammation.
abstract: Chronic thromboembolic pulmonary hypertension (CTEPH) is one of the leading causes of severe pulmonary hypertension. According to previously reported studies in the pertinent literature, chronic inflammatory conditions may be implicated in the development of CTEPH. We herein describe the case of a 56-year-old woman who was diagnosed with CTEPH in association with chronic infection. The patient had experienced five episodes of pneumonia in the five years prior to the diagnosis of CTEPH. Blood tests from the previous five years of outpatient follow-up demonstrated that the C-reactive protein level was slightly elevated. This case suggests that a relationship exists between chronic inflammation and CTEPH, and furthermore, may contribute towards elucidating the pathophysiology of CTEPH.
authors.affiliation: Department of Pulmonary Medicine, Tokyo Metropolitan Hiroo General Hospital, Japan.
authors.forename: Naoyuki
authors.initials: N
authors.lastname: Kuse
authors.forename: Shinji
authors.initials: S
authors.lastname: Abe
authors.forename: Hidehiko
authors.initials: H
authors.lastname: Kuribayashi
authors.forename: Asami
authors.initials: A
authors.lastname: Fukuda
authors.forename: Yuji
authors.initials: Y
authors.lastname: Kusunoki
authors.forename: Ritsuko
authors.initials: R
authors.lastname: Narato
authors.forename: Hitoshi
authors.initials: H
authors.lastname: Saito
authors.forename: Akihiko
authors.initials: A
authors.lastname: Gemma
mesh_terms: D002097:C-Reactive Protein; D002908:Chronic Disease; D005260:Female; D006801:Humans; D006976:Hypertension, Pulmonary / Q000150:complications*; D007249:Inflammation / Q000150:complications*; D008875:Middle Aged; D011014:Pneumonia / Q000150:complications*; D011655:Pulmonary Embolism / Q000150:complications*
chemical_list: D002097:C-Reactive Protein