title: Cardiac Magnetic Resonance Imaging in Pediatric Turner Syndrome.
abstract: To compare the detection of cardiac lesions with the use of cardiac magnetic resonance imaging (CMR) and conventional echocardiography in children with Turner syndrome.
  
  
  
  Twenty-four girls with Turner syndrome, 8-18 years of age, were recruited through the Pediatric Endocrinology Program. Participants underwent CMR and echocardiography within a 2-year period, and discrepancies between the results of each modality were identified.
  
  
  
  Fifteen of 24 (63%) girls had a cardiac lesion identified on CMR or echocardiography. Both modalities identified the same lesion in 10 of 15 (67%); however, 6 of 15 (40%) participants had a lesion identified on CMR but not echocardiography. Participants with a missed lesion had a trend towards greater body mass index. Aortic dilation and bicuspid aortic valve were the most commonly missed lesions by echocardiography.
  
  
  
  CMR identifies significant cardiac lesions missed by echocardiography in pediatric patients with Turner syndrome, particularly along the aorta. These findings support the current guidelines that recommend screening CMR in addition to echocardiogram. Early identification of cardiac abnormalities in patients with Turner syndrome will allow for a greater understanding of the natural history in these patients and potentially identify candidates for earlier intervention.
authors.affiliation: Pediatric Endocrinology, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Scott
authors.initials: S
authors.lastname: Somerville
authors.affiliation: Pediatric Endocrinology, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Rosolowsky
authors.affiliation: Pediatric Cardiology, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada.
authors.forename: Somjate
authors.initials: S
authors.lastname: Suntratonpipat
authors.affiliation: Pediatric Endocrinology, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Rose
authors.initials: R
authors.lastname: Girgis
authors.affiliation: Pediatric Cardiology, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada.
authors.forename: Benjamin H
authors.initials: BH
authors.lastname: Goot
authors.affiliation: Pediatric Cardiology, University of Alberta, Stollery Children's Hospital, Edmonton, Alberta, Canada. Electronic address: etham@ualberta.ca.
authors.forename: Edythe B
authors.initials: EB
authors.lastname: Tham
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D004452:Echocardiography; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D008279:Magnetic Resonance Imaging; D014424:Turner Syndrome / Q000000981:diagnostic imaging*
keywords: aortic dilation; aortic dissection; echocardiography