title: Electrophilic activation of alkynes for enyne cycloisomerization reactions with in situ generated early/late heterobimetallic Pt-Ti catalysts.
abstract: In situ formation of heterobimetallic Pt-Ti catalysts enables rapid room temperature catalysis in enyne cycloisomerization reactions. The Lewis acidic titanium atom in the ligand framework is shown to be essential for fast catalysis. A range of enyne substrates are efficiently cyclized to carbocycles and heterocycles in high yield.
authors.affiliation: Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA. dmichaelis@chem.byu.edu.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Talley
authors.affiliation: Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA. dmichaelis@chem.byu.edu.
authors.forename: Ryjul W
authors.initials: RW
authors.lastname: Stokes
authors.affiliation: Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA. dmichaelis@chem.byu.edu.
authors.forename: Whitney K
authors.initials: WK
authors.lastname: Walker
authors.affiliation: Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT 84602, USA. dmichaelis@chem.byu.edu.
authors.forename: David J
authors.initials: DJ
authors.lastname: Michaelis