title: Acute tumor lysis syndrome after proximal splenic artery embolization.
abstract: Preoperative splenic artery embolization for massive splenomegaly has been shown to reduce intraoperative hemorrhage during splenectomy. We describe a case of tumor lysis syndrome after proximal splenic artery embolization in a patient with advanced mantle cell lymphoma and splenic involvement. The patient presented initially with hyperkalemia two days after embolization that worsened during splenectomy. He was stabilized, but developed laboratory tumor lysis syndrome with renal failure and expired. High clinical suspicion of tumor lysis syndrome in this setting is advised. Treatment must be started early to avoid serious renal injury and death. Lastly, same day splenectomy and embolization should be considered to decrease the likelihood of developing tumor lysis syndrome.
authors.affiliation: Department of Vascular Interventional Radiology, University of Miami, 1611 NW 12th Ave, Miami, FL 33136-1005, USA.
authors.forename: Jason T
authors.initials: JT
authors.lastname: Salsamendi
authors.affiliation: Department of Vascular Interventional Radiology, University of Miami, 1611 NW 12th Ave, Miami, FL 33136-1005, USA.
authors.forename: Mehul H
authors.initials: MH
authors.lastname: Doshi
authors.affiliation: Department of Vascular Interventional Radiology, University of Miami, 1611 NW 12th Ave, Miami, FL 33136-1005, USA.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Gortes
authors.affiliation: Department of General Surgery, University of Miami, 1120 NW 14th St, Miami, FL 33136-1005, USA.
authors.forename: Joe U
authors.initials: JU
authors.lastname: Levi
authors.affiliation: Department of Vascular Interventional Radiology, University of Miami, 1611 NW 12th Ave, Miami, FL 33136-1005, USA.
authors.forename: Govindarajan
authors.initials: G
authors.lastname: Narayanan
keywords: Hyperkalemia; Mantle cell lymphoma; Proximal splenic artery embolization; Splenic artery embolization; Splenomegaly; Tumor lysis syndrome; splenectomy