title: Fabrication of 3D Biomimetic Microfluidic Networks in Hydrogels.
abstract: A laser-based hydrogel degradation technique is developed that allows for local control over hydrogel porosity, fabrication of 3D vascular-derived, biomimetic, hydrogel-embedded microfluidic networks, and generation of two intertwining, yet independent, microfluidic networks in a single construct.
authors.affiliation: Department of Biomedical Engineering, University of Delaware, 150 Academy Street161 Colburn Lab, Newark, DE, 19716, USA.
authors.forename: Keely A
authors.initials: KA
authors.lastname: Heintz
authors.affiliation: Department of Biomedical Engineering, University of Delaware, 150 Academy Street161 Colburn Lab, Newark, DE, 19716, USA.
authors.forename: Michael E
authors.initials: ME
authors.lastname: Bregenzer
authors.affiliation: Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Colburn Lab, Newark, DE, 19716, USA.|Delaware Biotechnology Institute, 15 Innovation Way, Newark, DE, 19711, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Mantle
authors.affiliation: Department of Chemical and Biomolecular Engineering, University of Delaware, 150 Academy Street, Colburn Lab, Newark, DE, 19716, USA.|Delaware Biotechnology Institute, 15 Innovation Way, Newark, DE, 19711, USA.
authors.forename: Kelvin H
authors.initials: KH
authors.lastname: Lee
authors.affiliation: Department of Biomedical Engineering, Duke University, 101 Science Drive, 1427 Fitzpatrick Center, Durham, NC, 27708, USA.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: West
authors.affiliation: Department of Biomedical Engineering, University of Delaware, 150 Academy Street161 Colburn Lab, Newark, DE, 19716, USA. jhslater@udel.edu.|Delaware Biotechnology Institute, 15 Innovation Way, Newark, DE, 19711, USA. jhslater@udel.edu.
authors.forename: John H
authors.initials: JH
authors.lastname: Slater
mesh_terms: D040761:Biomimetic Materials / Q000737:chemistry*; D020100:Hydrogels / Q000737:chemistry*; D056656:Lab-On-A-Chip Devices
chemical_list: D020100:Hydrogels
keywords: biomimetic; laser-based degradation; microfluidic; tissue engineering; vascularized constructs