title: Alcoholic Beverage Consumption and Chronic Diseases.
abstract: Epidemiological and experimental studies have consistently linked alcoholic beverage consumption with the development of several chronic disorders, such as cancer, cardiovascular diseases, diabetes mellitus and obesity. The impact of drinking is usually dose-dependent, and light to moderate drinking tends to lower risks of certain diseases, while heavy drinking tends to increase the risks. Besides, other factors such as drinking frequency, genetic susceptibility, smoking, diet, and hormone status can modify the association. The amount of ethanol in alcoholic beverages is the determining factor in most cases, and beverage types could also make an influence. This review summarizes recent studies on alcoholic beverage consumption and several chronic diseases, trying to assess the effects of different drinking patterns, beverage types, interaction with other risk factors, and provide mechanistic explanations.
authors.affiliation: Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. zhouyue3@mail2.sysu.edu.cn.
authors.forename: Yue
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. zhengj37@mail2.sysu.edu.cn.
authors.forename: Jie
authors.initials: J
authors.lastname: Zheng
authors.affiliation: School of Chinese Medicine, The University of Hong Kong, Sassoon Road, Hong Kong 999077, China. lishasl0308@163.com.
authors.forename: Sha
authors.initials: S
authors.lastname: Li
authors.affiliation: Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. zwky740359@163.com.
authors.forename: Tong
authors.initials: T
authors.lastname: Zhou
authors.affiliation: Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. daidaolangman@126.com.
authors.forename: Pei
authors.initials: P
authors.lastname: Zhang
authors.affiliation: Guangdong Provincial Key Laboratory of Food, Nutrition and Health, School of Public Health, Sun Yat-Sen University, Guangzhou 510080, China. lihuabin@mail.sysu.edu.cn.|South China Sea Bioresource Exploitation and Utilization Collaborative Innovation Center, Sun Yat-Sen University, Guangzhou 510006, China. lihuabin@mail.sysu.edu.cn.
authors.forename: Hua-Bin
authors.initials: HB
authors.lastname: Li
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects*; D000434:Alcoholic Beverages / Q000009:adverse effects*; D000818:Animals; D002318:Cardiovascular Diseases / Q000453:epidemiology; D002908:Chronic Disease; D003920:Diabetes Mellitus / Q000453:epidemiology; D006801:Humans; D009369:Neoplasms / Q000453:epidemiology; D009765:Obesity / Q000453:epidemiology
keywords: alcoholic beverage; cancer; cardiovascular disease; diabetes; obesity; wine