title: Pyogenic vertebral osteomyelitis caused by Yersinia pseudotuberculosis.
abstract: Septic vertebral osteomyelitis caused by Yersinia pseudotuberculosis is extremely rare. We report the first case of pyogenic vertebral osteomyelitis due to Y. pseudotuberculosis. A 65-year-old man presented with low back pain and fever. He had a history of psoriasis vulgaris treated with adalimumab. The patient reported drinking adequate amounts of well water daily. Clinical examination revealed no neurological deficit of the lower limbs. Laboratory findings included increased inflammatory reactions. Magnetic resonance imaging showed diffuse changes in intensity at the T10 and L3 vertebrae, and multiple nodular lesions in the thoracic, lumbar, sacral, and iliac regions. We performed an open biopsy. Y. pseudotuberculosis was cultured from both the T10 and L3 vertebrae lesions. Y. pseudotuberculosis is sensitive to almost all antibiotics. After initiating antibiotic treatment, the laboratory parameters normalized and the patient recovered completely, without any neurological deficits. To our knowledge, our report represents the first case of pyogenic vertebral osteomyelitis due to Y. pseudotuberculosis.
authors.affiliation: Department of orthopaedic surgery, faculty of medicine, Oita university, 1-1, Idaigaoka, Hasama-machi, Yufu-shi, 879-5593 Oita, Japan.
authors.forename: Toshinobu
authors.initials: T
authors.lastname: Ishihara
authors.affiliation: Department of orthopaedic surgery, faculty of medicine, Oita university, 1-1, Idaigaoka, Hasama-machi, Yufu-shi, 879-5593 Oita, Japan. Electronic address: masashim@oita-u.ac.jp.
authors.forename: Masashi
authors.initials: M
authors.lastname: Miyazaki
authors.affiliation: Department of orthopaedic surgery, faculty of medicine, Oita university, 1-1, Idaigaoka, Hasama-machi, Yufu-shi, 879-5593 Oita, Japan.
authors.forename: Toyomi
authors.initials: T
authors.lastname: Yoshiiwa
authors.affiliation: Department of orthopaedic surgery, faculty of medicine, Oita university, 1-1, Idaigaoka, Hasama-machi, Yufu-shi, 879-5593 Oita, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Notani
authors.affiliation: Department of orthopaedic surgery, faculty of medicine, Oita university, 1-1, Idaigaoka, Hasama-machi, Yufu-shi, 879-5593 Oita, Japan.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Tsumura
mesh_terms: D000368:Aged; D000071997:Blood Culture; D015780:Carbapenems / Q000008:administration & dosage; D002981:Clindamycin / Q000008:administration & dosage; D015299:Discitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000382:microbiology*; D000077726:Doripenem; D004359:Drug Therapy, Combination; D005334:Fever / Q000175:diagnosis / Q000209:etiology; D005500:Follow-Up Studies; D006801:Humans; D007262:Infusions, Intravenous; D017116:Low Back Pain / Q000175:diagnosis / Q000209:etiology; D008159:Lumbar Vertebrae; D008279:Magnetic Resonance Imaging / Q000379:methods; D008297:Male; D010019:Osteomyelitis / Q000000981:diagnostic imaging* / Q000188:drug therapy / Q000382:microbiology*; D035583:Rare Diseases; D013904:Thoracic Vertebrae; D016896:Treatment Outcome; D015011:Yersinia pseudotuberculosis / Q000187:drug effects / Q000302:isolation & purification*; D015012:Yersinia pseudotuberculosis Infections / Q000175:diagnosis / Q000188:drug therapy
chemical_list: D015780:Carbapenems; D002981:Clindamycin; D000077726:Doripenem
keywords: MRI; Pyogenic vertebral osteomyelitis; Yersinia pseudotuberculosis