title: Use of surrogate end points in healthcare policy: a proposal for adoption of a validation framework.
authors.affiliation: Evidence Synthesis and Modelling for Health Improvement, Institute of Health Research, University of Exeter Medical School, Exeter EX1 2LU, UK; and the Centre for Research on Health and Social Care Management, Bocconi University, 20100 Milan, Italy.
authors.forename: Oriana
authors.initials: O
authors.lastname: Ciani
authors.affiliation: International Drug Development Institute, 1340 Louvain-la-Neuve, Belgium.
authors.forename: Marc
authors.initials: M
authors.lastname: Buyse
authors.affiliation: Centre for Health Economics, University of York, York YO10 5DD, UK.
authors.forename: Mike
authors.initials: M
authors.lastname: Drummond
authors.affiliation: European Medicine Agency, London E14 5EU, UK; and the University of Rome Tor Vergata, 00173 Rome, Italy.
authors.forename: Guido
authors.initials: G
authors.lastname: Rasi
authors.affiliation: Dendrix Research, 04534-000 Sao Paulo, Brazil.
authors.forename: Everardo D
authors.initials: ED
authors.lastname: Saad
authors.affiliation: Evidence Synthesis and Modelling for Health Improvement, Institute of Health Research, University of Exeter Medical School, Exeter EX1 2LU, UK.
authors.forename: Rod S
authors.initials: RS
authors.lastname: Taylor
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D003695:Delivery of Health Care / Q000331:legislation & jurisprudence*; D006287:Health Planning Guidelines; D006801:Humans; D015201:Meta-Analysis as Topic; D008962:Models, Theoretical; D054928:Validation Studies as Topic
chemical_list: D015415:Biomarkers