title: Current and Evolving Methods to Visualize Biological Data in Cancer Research.
abstract: Although the measurements of clinical outcomes for cancer treatments have become diverse and complex, there remains a need for clear, easily interpreted representations of patients' experiences. With oncology trials increasingly reporting non-time-to-event outcomes, data visualization has evolved to incorporate parameters such as responses to therapy, duration and degree of response, and novel representations of underlying tumor biology. We review both commonly used and newly developed methods to display outcomes in oncology, with a focus on those that have evolved to represent complex datasets.
authors.affiliation: Department of Medical Oncology and Olivia-Newton John Cancer Research Institute, Austin Health, Melbourne, Australia (PLC, TJ); School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia (CG); Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada (PCB); Department of Medical Biophysics and Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada (PCB); Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (PWP) PueyLing.Chia@onjcri.org.au.
authors.forename: Puey Ling
authors.initials: PL
authors.lastname: Chia
authors.affiliation: Department of Medical Oncology and Olivia-Newton John Cancer Research Institute, Austin Health, Melbourne, Australia (PLC, TJ); School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia (CG); Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada (PCB); Department of Medical Biophysics and Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada (PCB); Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (PWP).
authors.forename: Craig
authors.initials: C
authors.lastname: Gedye
authors.affiliation: Department of Medical Oncology and Olivia-Newton John Cancer Research Institute, Austin Health, Melbourne, Australia (PLC, TJ); School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia (CG); Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada (PCB); Department of Medical Biophysics and Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada (PCB); Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (PWP).
authors.forename: Paul C
authors.initials: PC
authors.lastname: Boutros
authors.affiliation: Department of Medical Oncology and Olivia-Newton John Cancer Research Institute, Austin Health, Melbourne, Australia (PLC, TJ); School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia (CG); Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada (PCB); Department of Medical Biophysics and Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada (PCB); Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (PWP).
authors.forename: Paul
authors.initials: P
authors.lastname: Wheatley-Price
authors.affiliation: Department of Medical Oncology and Olivia-Newton John Cancer Research Institute, Austin Health, Melbourne, Australia (PLC, TJ); School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle, New Lambton Heights, Australia (CG); Informatics & Biocomputing Program, Ontario Institute for Cancer Research, Toronto, Canada (PCB); Department of Medical Biophysics and Department of Pharmacology & Toxicology, University of Toronto, Toronto, Canada (PCB); Ottawa Hospital Research Institute and Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada (PWP).
authors.forename: Thomas
authors.initials: T
authors.lastname: John
mesh_terms: D035843:Biomedical Research; D002986:Clinical Trials as Topic; D003196:Computer Graphics / Q000639:trends*; D018572:Disease-Free Survival; D005838:Genotype; D006801:Humans; D053208:Kaplan-Meier Estimate; D009369:Neoplasms / Q000235:genetics / Q000628:therapy*; D010641:Phenotype; D012107:Research Design; D015996:Survival Rate