title: Small-angle scattering and 3D structure interpretation.
abstract: This review focuses on advances in the application of solution small-angle scattering (SAS) in structural analysis of biomolecules and the complexes they form. Examples highlighted illustrate the unique contribution of SAS, using both X-rays and neutrons, in hybrid or integrative modelling methods. The increased information content when neutron scattering with contrast variation is used is a particular focus. Finally, progress toward an agreed reporting framework, the development of open data and model archives, and the importance of these initiatives is covered.
authors.affiliation: The University of Sydney, New South Wales 2006, Australia. Electronic address: jill.trewhella@sydney.edu.au.
authors.forename: Jill
authors.initials: J
authors.lastname: Trewhella
mesh_terms: D046911:Macromolecular Substances / Q000737:chemistry*; D009682:Magnetic Resonance Spectroscopy; D008968:Molecular Conformation; D033363:Neutron Diffraction; D053838:Scattering, Small Angle; D014961:X-Ray Diffraction
chemical_list: D046911:Macromolecular Substances