title: Comparison between Focus Harmonic scalpel and other hemostatic techniques in open thyroidectomy: A systematic review and meta-analysis.
abstract: The purpose of this review was to compare the efficacy and surgical outcomes of total thyroidectomy between the Focus Harmonic scalpel (Ethicon, Cincinnati, OH) and other hemostatic procedures.
  
  
  
  An extensive search was conducted using the PubMed and Cochrane databases from January 2008 to October 2014. Operating time, blood loss, pain, complications, and hospital stay were evaluated.
  
  
  
  When compared with conventional techniques or LigaSure Precise Vessel Sealing System (Medtronic, Minneapolis, MN), the use of the Focus Harmonic scalpel reduced operative time by 22,428 minutes and blood loss by 13,914 mL. Length of hospital stay was significantly shorter in the Focus Harmonic scalpel group with a mean reduction of 0.410 days.
  
  
  
  According to our meta-analysis, when comparing the Focus Harmonic scalpel versus conventional techniques, it seems evident that the use of this device in thyroid surgery is associated with a mean reduction in operating time, blood loss, and hospital stay, without any increase in pain and complications. There was no appreciable difference between the Focus Harmonic scalpel and the LigaSure Precise Vessel Sealing System. © 2016 Wiley Periodicals, Inc. Head Neck 38: First-1578, 2016.
authors.affiliation: Department of "Scienze Mediche, Chirurgiche e tecnologie Avanzate - G. F. Ingrassia", University of Catania, Endocrine Surgery Unit, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy. cannizzaromatteoangelo@yahoo.it.
authors.forename: Matteo Angelo
authors.initials: MA
authors.lastname: Cannizzaro
authors.affiliation: Department of General Surgery and Senology Unit, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy.
authors.forename: Laura
authors.initials: L
authors.lastname: Borzì
authors.affiliation: Department of Endocrine Surgery, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Lo Bianco
authors.affiliation: Department of Endocrine Surgery, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy.
authors.forename: Valeriya
authors.initials: V
authors.lastname: Okatyeva
authors.affiliation: Department of General Surgery and Senology Unit, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Cavallaro
authors.affiliation: Department of Endocrine Surgery, "Policlinico-Vittorio Emanuele" Hospital, Catania, Italy.
authors.forename: Antonino
authors.initials: A
authors.lastname: Buffone
mesh_terms: D016063:Blood Loss, Surgical; D006488:Hemostasis, Surgical / Q000295:instrumentation*; D006801:Humans; D007902:Length of Stay; D061646:Operative Time; D011183:Postoperative Complications; D013525:Surgical Instruments; D013965:Thyroidectomy / Q000295:instrumentation* / Q000379:methods
keywords: Focus Harmonic scalpel; hemostasis; meta-analysis; surgical techniques; thyroidectomy