title: Chemical composition and biological activities of essential oil from Filifolium sibiricum (L.) Kitam.
abstract: The essential oil from Filifolium sibiricum (L.) Kitam were extracted using hydrodistillation and GC-MS was used to analyse the essential oil. The main components were espatulenol (8.55%), geranyl acetate (8.03%), caryophyllene oxide (5.47%), calamenene (4.79%), geraniol (4.28%), calamenene (4.53%), geraniol (4.06%), cedrene epoxide (3.23%), myrtenol (3.18%), transgeranylgeranio (3.13%), etc. The essential oil showed intensive inhibitory effects against MCF-7 with IC50level of 0.78 mg/mL, HepG-2 with IC50level of 0.44 mg/mL, SKOV-3 with IC50level of 0.27 mg/mL, BGC-823 with IC50level of 0.34 mg/mL. In the antibacterial test, the essential oil showed the significant antibacterial activities. The MIC and MBC values were 5.20 and 5.20 mg/mL against Staphylococcus aureus.
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Shanshan
authors.initials: S
authors.lastname: Liang
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Wei
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Juan
authors.initials: J
authors.lastname: Xue
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Yichun
authors.initials: Y
authors.lastname: Sun
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Zhili
authors.initials: Z
authors.lastname: Chen
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Haixue
authors.initials: H
authors.lastname: Kuang
authors.affiliation: a Key Laboratory of Chinese Materia Medica(Ministry of Education) , Heilongjiang University of Chinese Medicine , Harbin , China.
authors.forename: Qiuhong
authors.initials: Q
authors.lastname: Wang
keywords:  (L.) Kitam; GCMS; antibacterial activity; cytotoxicity; essential oil