title: Rosai-Dorfman Disease Isolated to the Thoracic Epidural Spine.
abstract: Rosai-Dorfman disease is a rare benign histiocytic disease that infrequently presents in the spine. We report a case of Rosai-Dorfman disease isolated to the epidural thoracic spine in a 26-year-old male. To our knowledge, this is the 15th reported case of isolated spinal disease and only the fourth case of isolated thoracic epidural disease. Given its rarity as well as non-specific symptoms and imaging findings, Rosai-Dorfman disease is often not considered and misdiagnosed on imaging studies. To help improve awareness of Rosai-Dorfman spinal disease, we review the literature and discuss the epidemiology, clinical presentation, imaging features, and treatment considerations for this condition.
authors.affiliation: School of Medicine, University of California, San Francisco, CA, USA.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Kozak
authors.affiliation: Department of Radiology and Biomedical Imaging, San Francisco General Hospital, San Francisco CA, USA; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Talbott
authors.affiliation: Department of Radiology and Biomedical Imaging, San Francisco General Hospital, San Francisco CA, USA.
authors.forename: Alina
authors.initials: A
authors.lastname: Uzelac
authors.affiliation: Department of Radiology and Biomedical Imaging, San Francisco General Hospital, San Francisco CA, USA; Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA, USA.
authors.forename: Bhavya
authors.initials: B
authors.lastname: Rehani
mesh_terms: D000328:Adult; D003937:Diagnosis, Differential; D015618:Histiocytosis, Sinus / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D013122:Spinal Diseases / Q000000981:diagnostic imaging* / Q000601:surgery; D013904:Thoracic Vertebrae / Q000000981:diagnostic imaging* / Q000601:surgery; D014057:Tomography, X-Ray Computed
keywords: MRI; Rosai-Dorfman; epidural; histiocytic disease; sinus histiocytosis with massive lymphadenopathy; spine; thoracic