title: Cross-sectional and prospective impact of reallocating sedentary time to physical activity on children's body composition.
abstract: The amount of time children spend in sedentary behaviours may have adverse health effects.
  
  
  
  To examine the substitution effects of displacing a fixed duration of sedentary time with physical activity (PA) on children's body composition.
  
  
  
  We included 386 children (197 boys). Outcomes were body mass index, waist circumference, total body fat mass and trunk fat mass assessed by dual-energy X-ray absorptiometry. Sedentary time and PA were measured with accelerometers. Data were analysed by isotemporal analyses estimating the effect of reallocating 15 and 30 min d-1of sedentary time into light (light physical activity), and moderate-to-vigorous (MVPA) PA on body composition.
  
  
  
  Reallocating 15 and 30 min d-1of sedentary time into MVPA was negatively associated with body fatness in cross-sectional analyses. Prospectively, reallocating 30 min of sedentary time into 30 min of MVPA was negatively associated with waist circumference (β = -1.11, p < 0.05), trunk fat mass (β = -0.21, p < 0.05), and total body fat mass (β = -0.48, p < 0.05) at follow-up (20 months). The magnitude of associations was half in magnitude and remained significant (p < 0.05) when reallocating 15 min of sedentary time into MVPA. Reallocating sedentary time into light physical activity was not related (p > 0.05) with body fatness outcomes.
  
  
  
  Substituting sedentary time with MVPA using isotemporal analysis is associated with positive effects on body composition.
authors.affiliation: Interdisciplinary Center for the Study of Human Performance (CIPER), Exercise and Health Laboratory, Faculty of Human Kinetics, Universide de Lisboa, Cruz Quebrada, Portugal.
authors.forename: Luís B
authors.initials: LB
authors.lastname: Sardinha
authors.affiliation: Interdisciplinary Center for the Study of Human Performance (CIPER), Faculty of Human Kinetics, Universidade de Lisboa, Cruz Quebrada, Portugal.
authors.forename: Adilson
authors.initials: A
authors.lastname: Marques
authors.affiliation: Interdisciplinary Center for the Study of Human Performance (CIPER), Exercise and Health Laboratory, Faculty of Human Kinetics, Universide de Lisboa, Cruz Quebrada, Portugal.
authors.forename: Cláudia
authors.initials: C
authors.lastname: Minderico
authors.affiliation: Department of Sport Medicine, Norwegian School of Sport Sciences, Oslo, Norway.|MRC Epidemiology Unit, University of Cambridge, Cambridge, UK.
authors.forename: Ulf
authors.initials: U
authors.lastname: Ekelund
mesh_terms: D015502:Absorptiometry, Photon; D061725:Accelerometry; D000273:Adipose Tissue; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002648:Child; D003430:Cross-Sectional Studies; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D057185:Sedentary Behavior; D055105:Waist Circumference
keywords: Body composition; isotemporal; physical activity; sedentary time