title: [Nasal Mucosa Absorption of Scutellariae Radix Extract in Rats and Its Two Preparations Phospholipid Complex and Submicron Emulsion].
abstract: OBJECTIVE
  To study the nasal mucosa absorption of Scutellariae Radix extract in rats and its two preparations phospholipid complex and submicron emulsion, and to evaluate the rationality of Scutellariae Radix extract modification technology and preparation form.
  
  
  METHODS
  According to the nasal absorption method, the absorption amount of Scutellariae Radix extract, phospholipid complex and submicron emulsion were determined.
  
  
  RESULTS
  The absorption amount of Scutellariae Radix extract, phospholipid complex and submicron emulsion under the experimental conditions was improved in turn in 2 h and the absorption amount of submicron emulsion increased significantly. The absorption characteristics were passive diffusion.
  
  
  CONCLUSIONS
  The modification methods and preparation form of Scutellariae Radix extract were scientific and reasonable.
authors.forename: Ya-jun
authors.initials: YJ
authors.lastname: Shi
authors.forename: Jun-hui
authors.initials: JH
authors.lastname: Shi
authors.forename: Ming
authors.initials: M
authors.lastname: Yang
mesh_terms: D000818:Animals; D004655:Emulsions / Q000737:chemistry; D009297:Nasal Mucosa / Q000378:metabolism*; D010743:Phospholipids / Q000737:chemistry; D010936:Plant Extracts / Q000493:pharmacokinetics*; D051381:Rats; D031364:Scutellaria baicalensis / Q000737:chemistry*
chemical_list: D004655:Emulsions; D010743:Phospholipids; D010936:Plant Extracts; C499814:Scutellaria baicalensis extract