title: Pathogens Causing Upper Respiratory Tract Infections in Outpatients.
abstract: The aim of the present study was to determine the results of typical and atypical bacteria microbiological tests in patients with symptoms of chronic cough. We investigated 230 outpatients aged from 1 to 83 years (112 female, 72 male, and 46 children) who were free of any respiratory tract infection at the time of study. The material for the investigation consisted of pharyngeal swabs. Two hundred and thirty pharyngeal swabs were examined for Chlamydia pneumoniae antigen and for typical pathogens each. Chlamydia pneumoniae antigen was detected using an indirect immunofluorescence test and classical microbiological culture was used for the detection of typical bacteria. The antigen was found in 44/230 (19.1 %) patients with chronic cough (23 women, 13 men, and 8 children). Positive culture for typical pathogens was observed in 65/230 (28.3 %) patients (37 women, 14 men, and 14 children). Simultaneous occurrence of Chlamydia pneumoniae and typical pathogens such as Staphylococcus aureus, Streptococcus pyogenes, Moraxella catarrhalis, and Haemophilus influenzae, was observed in 11/230 (4.8 %) patients. The results show that in patients with chronic cough Chlamydia pneumoniae is detected less frequently than the typical pathogens are. A search for atypical bacteria in patients with chronic cough is needed to be able to conduct effective and sufficiently long therapy.
authors.affiliation: Department of Basic Sciences, Wroclaw Medical University, 4 Chałubińskiego St, 50-368, Wrocław, Poland. agnieszka.jama-kmiecik@umed.wroc.pl.
authors.forename: A
authors.initials: A
authors.lastname: Jama-Kmiecik
authors.affiliation: Department of Basic Sciences, Wroclaw Medical University, 4 Chałubińskiego St, 50-368, Wrocław, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Frej-Mądrzak
authors.affiliation: Department of Basic Sciences, Wroclaw Medical University, 4 Chałubińskiego St, 50-368, Wrocław, Poland.
authors.forename: J
authors.initials: J
authors.lastname: Sarowska
authors.affiliation: Department of Basic Sciences, Wroclaw Medical University, 4 Chałubińskiego St, 50-368, Wrocław, Poland.
authors.forename: I
authors.initials: I
authors.lastname: Choroszy-Król
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D016993:Chlamydophila pneumoniae / Q000302:isolation & purification*; D003371:Cough / Q000382:microbiology*; D005260:Female; D006193:Haemophilus influenzae / Q000302:isolation & purification*; D006801:Humans; D007223:Infant; D008297:Male; D008875:Middle Aged; D001936:Moraxella catarrhalis / Q000302:isolation & purification*; D012141:Respiratory Tract Infections / Q000382:microbiology*; D013211:Staphylococcus aureus / Q000302:isolation & purification*; D013297:Streptococcus pyogenes / Q000302:isolation & purification*; D055815:Young Adult
keywords: Atypical bacteria; Chlamydia pneumoniae; Co-infection; Culture; Pathogen detection; Pharyngeal swabs