title: Mouse Models of Chikungunya Virus.
abstract: The majority of medical advances have been made using animals. Studies using mouse models of chikungunya-induced disease have proven invaluable for dissecting the intricate nature of the immune response to this viral infection and identifying potential targets for the development of treatment strategies. Herein we describe the common mouse models used to research the pathobiology of chikungunya virus infection to date.
authors.affiliation: Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University-Gold Coast Campus, Parklands Drive, Southport, QLD, 4222, Australia.
authors.forename: Lara J
authors.initials: LJ
authors.lastname: Herrero
authors.affiliation: Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University-Gold Coast Campus, Parklands Drive, Southport, QLD, 4222, Australia.
authors.forename: Penny A
authors.initials: PA
authors.lastname: Rudd
authors.affiliation: Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University-Gold Coast Campus, Parklands Drive, Southport, QLD, 4222, Australia.
authors.forename: Xiang
authors.initials: X
authors.lastname: Liu
authors.affiliation: Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University-Gold Coast Campus, Parklands Drive, Southport, QLD, 4222, Australia.
authors.forename: Stefan
authors.initials: S
authors.lastname: Wolf
authors.affiliation: Emerging Viruses and Inflammation Research Group, Institute for Glycomics, Griffith University-Gold Coast Campus, Parklands Drive, Southport, QLD, 4222, Australia. s.mahalingam@griffith.edu.au.
authors.forename: Suresh
authors.initials: S
authors.lastname: Mahalingam
mesh_terms: D000818:Animals; D065632:Chikungunya Fever / Q000276:immunology / Q000473:pathology*; D002646:Chikungunya virus / Q000276:immunology / Q000472:pathogenicity*; D004195:Disease Models, Animal; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL
keywords: Chikungunya; In vivo infections; Intracerebral; Intranasal; Mus musculus; Subcutaneous