title: Exopisiod B and farylhydrazone C, two new alkaloids from the Antarctic-derived fungus Penicillium sp. HDN14-431.
abstract: Two new compounds, exopisiod B (1) and farylhydrazone C (2), together with two known compounds (3-4), were isolated from the Antarctic-derived fungus Penicillium sp. HDN14-431. Their structures including absolute configurations were elucidated by spectroscopic methods and TDDFT ECD calculations. The cytotoxicity and antimicrobial activities of all compounds were tested.
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Ting
authors.initials: T
authors.lastname: Zhang
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Mei-Lin
authors.initials: ML
authors.lastname: Zhu
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Guang-Yu
authors.initials: GY
authors.lastname: Sun
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Na
authors.initials: N
authors.lastname: Li
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Qian-Qun
authors.initials: QQ
authors.lastname: Gu
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: De-Hai
authors.initials: DH
authors.lastname: Li
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Che
authors.affiliation: a Key Laboratory of Marine Drugs, Chinese Ministry of Education , School of Medicine and Pharmacy, Ocean University of China , Qingdao 266003 , China.
authors.forename: Tian-Jiao
authors.initials: TJ
authors.lastname: Zhu
mesh_terms: D000470:Alkaloids / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D000864:Antarctic Regions; D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D002176:Candida albicans / Q000187:drug effects; D004354:Drug Screening Assays, Antitumor; D006835:Hydrazones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008826:Microbial Sensitivity Tests; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D010407:Penicillium / Q000737:chemistry*
chemical_list: D000470:Alkaloids; D000900:Anti-Bacterial Agents; D006835:Hydrazones; C000613849:exopisiod B; C000613850:farylhydrazone C
keywords: Antarctic-derived fungus; ECD calculations; Exopisiod; absolute configuration; farylhydrazone