title: HLA-A, -B, -DRB1 allele and haplotype frequencies of 920 cord blood units from Central Chile.
abstract: We present human leukocyte antigen (HLA) haplotype and allele/antigenic group frequencies derived from a data set of 920 umbilical cord blood units collected in Central Chile. HLA-A and -B genotypes were typed using sequence specific oligonucleotide probe methods while HLA-DRB1 genotypes were obtained from sequencing-based typing. The most frequent haplotype is A*29~B*44~DRB1*07:01 with an estimated frequency of 2.1%.
authors.affiliation: DKMS German Bone Marrow Donor Center, Tübingen, Germany. Electronic address: cschaefer@dkms.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Schäfer
authors.affiliation: DKMS German Bone Marrow Donor Center, Tübingen, Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Sauter
authors.affiliation: DKMS German Bone Marrow Donor Center, Tübingen, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Riethmüller
authors.affiliation: Kashi Clinical Laboratories, Portland, USA.
authors.forename: Zahra Mehdizadeh
authors.initials: ZM
authors.lastname: Kashi
authors.affiliation: DKMS German Bone Marrow Donor Center, Tübingen, Germany.
authors.forename: Alexander H
authors.initials: AH
authors.lastname: Schmidt
authors.affiliation: Vidacel Cord Blood Bank, Santiago, Chile.
authors.forename: Francisco J
authors.initials: FJ
authors.lastname: Barriga
mesh_terms: D001483:Base Sequence; D001782:Blood Donors; D001803:Blood Transfusion; D002677:Chile; D005312:Fetal Blood; D005787:Gene Frequency; D005838:Genotype; D015788:HLA-A1 Antigen / Q000235:genetics*; D015235:HLA-B Antigens / Q000235:genetics*; D059811:HLA-DRB1 Chains / Q000235:genetics*; D006801:Humans; D008969:Molecular Sequence Data; D011110:Polymorphism, Genetic
chemical_list: D015788:HLA-A1 Antigen; D015235:HLA-B Antigens; D059811:HLA-DRB1 Chains
keywords: Bioinformatics; HLA alleles; Population genetics