title: Tales of Antigen Evasion from CAR Therapy.
abstract: Both T cells bearing chimeric antigen receptors and tumor-specific antibodies can successfully target some malignancies, but antigen escape can lead to relapse. Two articles in this issue of Cancer Immunology Research explore what effective countermeasures may prevent it. Cancer Immunol Res; 4(6); 473-473. ©2016 AACRSee articles by Zah et al., p. 498, and Rufener et al., p. 509.
authors.affiliation: Center for Cell Engineering, Memorial Sloan Kettering Cancer Center. m-sadelain@ski.mskcc.org.
authors.forename: Michel
authors.initials: M
authors.lastname: Sadelain
mesh_terms: D006801:Humans; D016219:Immunotherapy, Adoptive; D009369:Neoplasms / Q000276:immunology; D011948:Receptors, Antigen, T-Cell / Q000276:immunology; D013601:T-Lymphocytes / Q000276:immunology*
chemical_list: D011948:Receptors, Antigen, T-Cell