title: Association between Chronic Periodontitis and Oral/Oropharyngeal Cancer.
abstract: The aim of this case control study was to assess the association between the extent and severity of chronic periodontitis and oral cavity and/or oropharyngeal cancer. The case group comprised 35 patients (mean age 56.1±8.4), diagnosed for oral and/or oropharyngeal cancer. The control group comprised 40 individuals (mean age 55.4±9.4) without diagnostic of cancer. All individuals were subjected to a periodontal examination, including bleeding on probing, plaque index, gingival index, probing pocket depth (PPD), clinical attachment loss (CAL), and decayed, extracted and filled teeth index (DMFT). The case group had significantly more sites with plaque. GI and BOP had similar values in both groups. The median PPD and CAL values were significantly higher for the case group. Chronic generalized periodontitis was predominant in 80% of patients with oral and/or oropharyngeal cancer. Eighty nine percent of the patients in the case group presented severe chronic periodontitis. There was no significant difference between groups for median values of DMFT. The extent and severity of chronic periodontitis remained as risk indicators for oral cavity and/or oropharyngeal cancer even after the adjustments for traditional confound factors, i.e. smoking and alcohol consumption.
authors.affiliation: Department of Periodontology, Dental School, UERJ - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil, Universidade do Estado do Rio de Janeiro, Universidade do Estado do Rio de Janeiro, Rio de Janeiro RJ , Brazil.
authors.forename: Renata Costa de
authors.initials: RC
authors.lastname: Moraes
authors.affiliation: Department of Head and Neck Surgery, INCA - Instituto Nacional do Câncer, Rio de Janeiro, RJ, Brazil, Instituto Nacional do Câncer, Instituto Nacional do Câncer, Rio de Janeiro RJ , Brazil.
authors.forename: Fernando Luiz
authors.initials: FL
authors.lastname: Dias
authors.affiliation: Department of Periodontology, Dental School, UERJ - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil, Universidade do Estado do Rio de Janeiro, Universidade do Estado do Rio de Janeiro, Rio de Janeiro RJ , Brazil.
authors.forename: Carlos Marcelo da Silva
authors.initials: CM
authors.lastname: Figueredo
authors.affiliation: Department of Periodontology, Dental School, UERJ - Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil, Universidade do Estado do Rio de Janeiro, Universidade do Estado do Rio de Janeiro, Rio de Janeiro RJ , Brazil.
authors.forename: Ricardo Guimarães
authors.initials: RG
authors.lastname: Fischer
mesh_terms: D000328:Adult; D000368:Aged; D055113:Chronic Periodontitis / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009959:Oropharyngeal Neoplasms / Q000150:complications*; D010514:Periodontal Pocket