title: Multi-modal adaptive optics system including fundus photography and optical coherence tomography for the clinical setting.
abstract: We present a new compact multi-modal imaging prototype that combines an adaptive optics (AO) fundus camera with AO-optical coherence tomography (OCT) in a single instrument. The prototype allows acquiring AO fundus images with a field of view of 4°x4° and with a frame rate of 10fps. The exposure time of a single image is 10 ms. The short exposure time results in nearly motion artifact-free high resolution images of the retina. The AO-OCT mode allows acquiring volumetric data of the retina at 200kHz A-scan rate with a transverse resolution of ~4 µm and an axial resolution of ~5 µm. OCT imaging is acquired within a field of view of 2°x2° located at the central part of the AO fundus image. Recording of OCT volume data takes 0.8 seconds. The performance of the new system is tested in healthy volunteers and patients with retinal diseases.
authors.affiliation: Center of Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Matthias
authors.initials: M
authors.lastname: Salas
authors.affiliation: Center of Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Wolfgang
authors.initials: W
authors.lastname: Drexler
authors.affiliation: Imagine Eyes, 18 Rue Charles de Gaulle 91400 Orsay, France.
authors.forename: Xavier
authors.initials: X
authors.lastname: Levecq
authors.affiliation: Imagine Eyes, 18 Rue Charles de Gaulle 91400 Orsay, France.
authors.forename: Barbara
authors.initials: B
authors.lastname: Lamory
authors.affiliation: Department of Ophthalmology and Optometry, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Markus
authors.initials: M
authors.lastname: Ritter
authors.affiliation: Department of Ophthalmology and Optometry, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Sonja
authors.initials: S
authors.lastname: Prager
authors.affiliation: Department of Ophthalmology and Optometry, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Julia
authors.initials: J
authors.lastname: Hafner
authors.affiliation: Department of Ophthalmology and Optometry, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Ursula
authors.initials: U
authors.lastname: Schmidt-Erfurth
authors.affiliation: Center of Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringer Guertel 18-20 A-1090 Vienna, Austria.
authors.forename: Michael
authors.initials: M
authors.lastname: Pircher
keywords: (110.1080) Active or adaptive optics; (110.4500) Optical coherence tomography; (170.3890) Medical optics instrumentation; (170.4470) Ophthalmology