title: Palladium(II)-Catalyzed Tandem Synthesis of Acenes Using Carboxylic Acids as Traceless Directing Groups.
abstract: A straightforward synthetic strategy for generating useful anthracene derivatives was developed involving palladium(II)-catalyzed tandem transformation with carboxylic acids as traceless directing groups. Carboxyl-directed C-H alkenylation, carboxyl-directed secondary C-H activation and rollover, intramolecular C-C bond formation, and decarboxylative aromatization are proposed as the key steps in the tandem reaction pathway. This novel synthetic route utilizes a broad range of substrates and provides a convenient synthetic tool that allows access to acenes.
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Korea.|Center for Catalytic Hydrocarbon Functionalization Institute for Basic Science (IBS), Daejeon, 34141, Korea.
authors.forename: Kiho
authors.initials: K
authors.lastname: Kim
authors.affiliation: Center for Catalytic Hydrocarbon Functionalization Institute for Basic Science (IBS), Daejeon, 34141, Korea.
authors.forename: Dhananjayan
authors.initials: D
authors.lastname: Vasu
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Korea.|Center for Catalytic Hydrocarbon Functionalization Institute for Basic Science (IBS), Daejeon, 34141, Korea.
authors.forename: Honggu
authors.initials: H
authors.lastname: Im
authors.affiliation: Department of Chemistry, Korea Advanced Institute of Science and Technology, Daejeon, 34141, Korea. hongorg@kaist.ac.kr.|Center for Catalytic Hydrocarbon Functionalization Institute for Basic Science (IBS), Daejeon, 34141, Korea. hongorg@kaist.ac.kr.
authors.forename: Sungwoo
authors.initials: S
authors.lastname: Hong
keywords: C-H functionalization; acenes; decarboxylation; palladium; tandem reactions