title: [Genetically modified food and allergies - an update].
abstract: Approval by the European Commission is mandatory for placing genetically modified plants as food or feed on the market in member states of the European Union (EU). The approval is preceded by a safety assessment based on the guidance of the European Food Safety Authority EFSA. The assessment of allergenicity of genetically modified plants and their newly expressed proteins is an integral part of this assessment process. Guidance documents for the assessment of allergenicity are currently under revision. For this purpose, an expert workshop was conducted in Brussels on June 17, 2015. There, methodological improvements for the assessment of coeliac disease-causing properties of proteins, as well as the use of complex models for in vitro digestion of proteins were discussed. Using such techniques a refinement of the current, proven system of allergenicity assessment of genetically modified plants can be achieved.
authors.affiliation: Abt. Lebensmittelsicherheit, Bundesinstitut für Risikobewertung, Max-Dohrn-Str. 8-10, 10589, Berlin, Deutschland. Birgit.niemann@bfr.bund.de.
authors.forename: Birgit
authors.initials: B
authors.lastname: Niemann
authors.affiliation: Abt. Lebensmittelsicherheit, Bundesinstitut für Risikobewertung, Max-Dohrn-Str. 8-10, 10589, Berlin, Deutschland.
authors.forename: Annette
authors.initials: A
authors.lastname: Pöting
authors.affiliation: Abt. Lebensmittelsicherheit, Bundesinstitut für Risikobewertung, Max-Dohrn-Str. 8-10, 10589, Berlin, Deutschland.
authors.forename: Albert
authors.initials: A
authors.lastname: Braeuning
authors.affiliation: Abt. Lebensmittelsicherheit, Bundesinstitut für Risikobewertung, Max-Dohrn-Str. 8-10, 10589, Berlin, Deutschland.
authors.forename: Alfonso
authors.initials: A
authors.lastname: Lampen
mesh_terms: D005060:Europe; D005512:Food Hypersensitivity / Q000209:etiology* / Q000517:prevention & control*; D059022:Food Safety / Q000379:methods*; D030841:Food, Genetically Modified / Q000009:adverse effects* / Q000592:standards*; D005818:Genetic Engineering / Q000592:standards*; D017408:Guidelines as Topic; D006801:Humans; D030821:Plants, Genetically Modified / Q000009:adverse effects
keywords: Allergenicity; Food; Genetic engineering; Genetically modified plants; Safety assessment