title: Sleep Disordered Breathing and Adverse Pregnancy Outcomes.
abstract: Sleep disordered breathing (SDB) occurs in 0.6% to 15% of reproductive-aged women. Because of an overlap in symptoms of SDB and normal pregnancy findings, the diagnosis of SDB in pregnancy is challenging. The repetitive arousals, sleep fragmentation, and hypoxias experienced by patients with SDB lead to an increase in oxidative stress and inflammation. In the nonpregnant population SDB is associated with an increased risk of diabetes mellitus, heart disease, and stroke. Increasing evidence identifies an association between SDB in pregnancy and gestational diabetes, preeclampsia, and fetal growth abnormalities.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, 2 Tampa General Circle, 6th Floor, Tampa, FL 33606, USA. Electronic address: mcain@health.usf.edu.
authors.forename: Mary Ashley
authors.initials: MA
authors.lastname: Cain
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of South Florida Morsani College of Medicine, 2 Tampa General Circle, 6th Floor, Tampa, FL 33606, USA; Department of Community and Family Health, College of Public Health, University of South Florida, 2 Tampa General Circle, 6th Floor, Tampa, FL 33606, USA.
authors.forename: Judette M
authors.initials: JM
authors.lastname: Louis
mesh_terms: D005260:Female; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D011296:Prenatal Diagnosis / Q000379:methods*; D012307:Risk Factors; D012891:Sleep Apnea Syndromes / Q000150:complications*
keywords: Obesity; Obstructive sleep apnea; Preeclampsia; Pregnancy