title: Effect of non-specific interactions on formation and stability of specific complexes.
abstract: We introduce a simple model to describe the interplay between specific and non-specific interactions. We study the influence of various physical factors on the static and dynamic properties of the specific interactions of our model and show that contrary to intuitive expectations, non-specific interactions can assist in the formation of specific complexes and increase their stability. We then discuss the relevance of these results for biological systems.
authors.affiliation: Department of Physics, and Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan 52900, Israel.
authors.forename: Dino
authors.initials: D
authors.lastname: Osmanović
authors.affiliation: Department of Physics, and Institute of Nanotechnology and Advanced Materials, Bar-Ilan University, Ramat Gan 52900, Israel.
authors.forename: Yitzhak
authors.initials: Y
authors.lastname: Rabin
mesh_terms: D056831:Coordination Complexes / Q000737:chemistry*; D008956:Models, Chemical; D046912:Multiprotein Complexes / Q000737:chemistry; D011485:Protein Binding; D055672:Static Electricity; D013816:Thermodynamics
chemical_list: D056831:Coordination Complexes; D046912:Multiprotein Complexes