title: Transient hair loss during treatment with dimethyl-fumarate for multiple sclerosis.
abstract: BACKGROUND
  Dimethyl-fumarate is a recently approved drug for relapsing-remitting Multiple Sclerosis in Italy.
  
  
  METHODS
  A 55-year-old woman started therapy with dimethyl-fumarate on June 2014; it was well-tolerated aside from moderate flushing. Starting September 2014 she noticed a progressive hair loss, that neither the dermatological examination nor clinical and medical history nor blood investigations could explain. The hair loss slowed down after two months and was followed by a hair growth back.
  
  
  CONCLUSIONS
  Transient hair loss is not a reported side effect of dimethyl-fumarate therapy but by excluding any known cause we attributed it to the beginning of the new therapy.
authors.affiliation: Institute of Neurology, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Largo A. Gemelli 8, Rome, Italy.
authors.forename: Francesco Antonio
authors.initials: FA
authors.lastname: Losavio
authors.affiliation: Institute of Neurology, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Largo A. Gemelli 8, Rome, Italy.
authors.forename: Matteo
authors.initials: M
authors.lastname: Lucchini
authors.affiliation: Institute of Neurology, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Largo A. Gemelli 8, Rome, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: De Fino
authors.affiliation: Institute of Neurology, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Largo A. Gemelli 8, Rome, Italy.
authors.forename: Massimiliano
authors.initials: M
authors.lastname: Mirabella
authors.affiliation: Institute of Neurology, Department of Geriatrics, Neurosciences and Orthopedics, Catholic University, Largo A. Gemelli 8, Rome, Italy; Don Carlo Gnocchi Foundation, Italy. Electronic address: viviana.nociti@policlinicogemelli.it.
authors.forename: Viviana
authors.initials: V
authors.lastname: Nociti
mesh_terms: D000505:Alopecia / Q000139:chemically induced* / Q000473:pathology; D000069462:Dimethyl Fumarate / Q000009:adverse effects* / Q000627:therapeutic use; D005260:Female; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D020529:Multiple Sclerosis, Relapsing-Remitting / Q000188:drug therapy* / Q000473:pathology
chemical_list: D007166:Immunosuppressive Agents; D000069462:Dimethyl Fumarate
keywords: Dimethyl-fumarate; Disease modifying therapies; Hair loss; Multiple sclerosis; Side effect