title: Congenital Trismus From Brainstem Dysgenesis: Case Report and Review of Literature.
abstract: Trismus refers to any condition inducing limited mouth opening and may present as a result of acquired or congenital pathology. We present the case of a newborn who presented with severe, congenital trismus due to brainstem dysgenesis. We describe the course of his investigations, and a multidisciplinary approach to the management of his care and follow-up. To our knowledge, this is one of the earliest reported cases of congenital trismus attributable to brainstem dysgenesis. A literature review was conducted to provide an overview of the differential pathogenesis as it presents in congenital cases and discuss the complexity of managing congenital trismus due to brainstem dysgenesis in a neonate and infant.
authors.affiliation: Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada;
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Hong
authors.affiliation: Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Otolaryngology-Head and Neck Surgery, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada; and.
authors.forename: Lisa
authors.initials: L
authors.lastname: Caulley
authors.affiliation: Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada; Department of Otolaryngology-Head and Neck Surgery, University of Ottawa, The Ottawa Hospital, Ottawa, Ontario, Canada; and.
authors.forename: Scott
authors.initials: S
authors.lastname: Kohlert
authors.affiliation: Departments of Genetics.
authors.forename: Gail E
authors.initials: GE
authors.lastname: Graham
authors.affiliation: Neurology.
authors.forename: Hugh J
authors.initials: HJ
authors.lastname: McMillan
authors.affiliation: Pathology and Laboratory Medicine, and.
authors.forename: Jean
authors.initials: J
authors.lastname: Michaud
authors.affiliation: Otolaryngology-Head and Neck Surgery, University of Ottawa, Children's Hospital of Eastern Ontario, Ottawa, Ontario, Canada vaccani@cheo.on.ca.
authors.forename: Jean-Philippe
authors.initials: JP
authors.lastname: Vaccani
mesh_terms: D001933:Brain Stem / Q000002:abnormalities*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014313:Trismus / Q000151:congenital*