title: The Fundamental Role of NOX Family Proteins in Plant Immunity and Their Regulation.
abstract: NADPH oxidases (NOXs), also known as respiratory burst oxidase homologs (RBOHs), are the major source of reactive oxygen species (ROS), and are involved in many important processes in plants such as regulation of acclimatory signaling and programmed cell death (PCD). Increasing evidence shows that NOXs play crucial roles in plant immunity and their functions in plant immune responses are not as separate individuals but with other signal molecules such as kinases, Rac/Rop small GTPases and hormones, mediating a series of signal transmissions. In a similar way, NOX-mediated signaling also participates in abiotic stress response of plants. We summarized here the complex role and regulation mechanism of NOXs in mediating plant immune response, and the viewpoint that abiotic stress response of plants may be a kind of special plant immunity is also proposed.
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. yajingwang@nwsuaf.edu.cn.
authors.forename: Ya-Jing
authors.initials: YJ
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. weixiaoyongshengwu@163.com.
authors.forename: Xiao-Yong
authors.initials: XY
authors.lastname: Wei
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. xiuqingjing@nwsuaf.edu.cn.
authors.forename: Xiu-Qing
authors.initials: XQ
authors.lastname: Jing
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. shizhang7026330@163.com.
authors.forename: Yan-Li
authors.initials: YL
authors.lastname: Chang
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. ourcarrot@163.com.
authors.forename: Chun-Hong
authors.initials: CH
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. wangxiang1342@126.com.
authors.forename: Xiang
authors.initials: X
authors.lastname: Wang
authors.affiliation: State Key Laboratory of Crop Stress Biology in Arid Areas, College of Life Sciences, Northwest A&amp;F University, Yangling 712100, China. kunmingchen@nwsuaf.edu.cn.
authors.forename: Kun-Ming
authors.initials: KM
authors.lastname: Chen
mesh_terms: D018506:Gene Expression Regulation, Plant; D009247:NADH, NADPH Oxidoreductases / Q000378:metabolism*; D057865:Plant Immunity; D018521:Plant Physiological Phenomena; D010940:Plant Proteins / Q000378:metabolism*; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction; D013312:Stress, Physiological
chemical_list: D010940:Plant Proteins; D017382:Reactive Oxygen Species; D009247:NADH, NADPH Oxidoreductases
keywords: Ca2+; NADPH oxidases; abiotic stress; biotic stress; hormones; kinases; reactive oxygen species