title: Heparin plus aspirin for unstable angina.
abstract: Adding heparin to aspirin in the treatment of people with unstable angina reduces the risk of myocardial infarction or death, research suggests. A meta-analysis was undertaken of six randomised trials which compared aspirin alone with aspirin plus heparin. The overall summary relative risk of myocardial infarction or death during randomised treatment was 0.67 in those treated with aspirin plus heparin compared with those treated with heparin alone. The risk for recurrent ischaemic pain was 0.68, 0.82 for infarction or death two to 12 weeks post-randomisation, 1.03 for revascularisation and 1.99 for major bleeding.