title: Outcomes of colonic diverticulitis according to the reason of immunosuppression.
abstract: BACKGROUND
  The aims of this study were to analyze the relationship between the different causes of immunosuppression (IMS) and diverticulitis.
  
  
  METHODS
  IMS patients admitted for colonic diverticulitis were included in the study. Patients were divided in 5 groups according to the reasons of IMS: group I, chronic corticosteroid therapy; group II, transplant patients; group III, malignant neoplasm disease; group IV, chronic renal failure; group V, others immunosuppressant treatment. Rate of emergency surgery, outcomes in terms of postoperative mortality, and recurrence rate after nonoperative management were analyzed according to the reason of IMS.
  
  
  RESULTS
  Emergency surgery was performed in 76 patients (39.3%). It was needed more frequently in group I. Overall, postoperative mortality was of 31.6% and recurrence rate after successful nonoperative management occurred in 30 patients (27.8%). No differences were observed among the groups.
  
  
  CONCLUSIONS
  The rate of emergency surgery in IMS patients at the first episode of acute colonic diverticulitis is high. Elective surgery in IMS patients should be individually indicated according to persistence of symptoms or early recurrences.
authors.affiliation: Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona, and IDIBELL (Bellvitge Biomedical Investigation Institute), C/ Feixa Llarga s/n L'Hospitalet de Llobregat, 08907, Barcelona, Spain. Electronic address: sbn.biondo@gmail.com.
authors.forename: Sebastiano
authors.initials: S
authors.lastname: Biondo
authors.affiliation: Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona, and IDIBELL (Bellvitge Biomedical Investigation Institute), C/ Feixa Llarga s/n L'Hospitalet de Llobregat, 08907, Barcelona, Spain.
authors.forename: Loris
authors.initials: L
authors.lastname: Trenti
authors.affiliation: Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona, and IDIBELL (Bellvitge Biomedical Investigation Institute), C/ Feixa Llarga s/n L'Hospitalet de Llobregat, 08907, Barcelona, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Elvira
authors.affiliation: Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona, and IDIBELL (Bellvitge Biomedical Investigation Institute), C/ Feixa Llarga s/n L'Hospitalet de Llobregat, 08907, Barcelona, Spain.
authors.forename: Thomas
authors.initials: T
authors.lastname: Golda
authors.affiliation: Department of General and Digestive Surgery, Colorectal Unit, Bellvitge University Hospital, University of Barcelona, and IDIBELL (Bellvitge Biomedical Investigation Institute), C/ Feixa Llarga s/n L'Hospitalet de Llobregat, 08907, Barcelona, Spain.
authors.forename: Esther
authors.initials: E
authors.lastname: Kreisler
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D013505:Digestive System Surgical Procedures / Q000379:methods*; D004239:Diverticulitis, Colonic / Q000401:mortality / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D015994:Incidence; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology*; D012008:Recurrence; D012189:Retrospective Studies; D012720:Severity of Illness Index; D013030:Spain / Q000453:epidemiology; D015996:Survival Rate / Q000639:trends
keywords: Acute colonic diverticulitis; Immunosuppression; Mortality; Recurrence