title: Why is mechanism of action important in antidepressant treatment?
abstract: Antidepressants are one of the most common treatment strategies for patients diagnosed with major depressive disorder (MDD). However, antidepressant medications have different mechanisms of action that can theoretically and in practice affect how patients respond. Clinicians should assess their patients' symptoms and response to medication at every visit to determine whether or not the treatment is fully effective. Here, follow the case of Maria, a 42-year-old teacher who is experiencing her first depressive episode.
authors.forename: Thomas L
authors.initials: TL
authors.lastname: Schwartz
mesh_terms: D000328:Adult; D003865:Major Depressive Disorder / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D061218:Depressive Disorder, Treatment-Resistant / Q000175:diagnosis / Q000188:drug therapy* / Q000523:psychology; D004305:Dose-Response Relationship, Drug; D057915:Drug Substitution; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D020280:Sertraline / Q000627:therapeutic use*; D011795:Surveys and Questionnaires
chemical_list: D020280:Sertraline