title: Should we still use vitamin A to prevent bronchopulmonary dysplasia?
abstract: Bronchopulmonary dysplasia (BPD) is associated with significant short- and long-term morbidity in preterm infants, and it can be prevented in some infants with vitamin A prophylaxis. Vitamin A, once widely used in neonatal intensive care, was scarce for the last few years, but has become available again at a much higher price, leading to dilemmas about its routine use. In this review we discuss experimental, clinical and socioeconomic evidence related to BPD, and provide a framework for clinicians and policy-makers to evaluate the value of vitamin A treatment and make decisions about its use for prevention of BPD.
authors.affiliation: Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
authors.forename: X I
authors.initials: XI
authors.lastname: Couroucli
authors.affiliation: Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Placencia
authors.affiliation: Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
authors.forename: L A
authors.initials: LA
authors.lastname: Cates
authors.affiliation: Department of Pediatrics, Section of Neonatology, Texas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
authors.forename: G K
authors.initials: GK
authors.lastname: Suresh
mesh_terms: D001997:Bronchopulmonary Dysplasia / Q000191:economics* / Q000517:prevention & control*; D003362:Cost-Benefit Analysis; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D019102:Infant, Very Low Birth Weight; D016032:Randomized Controlled Trials as Topic; D014801:Vitamin A / Q000008:administration & dosage* / Q000191:economics*
chemical_list: D014801:Vitamin A