title: Cancer-related Stroke due to Mural Thrombus in the Extracranial Carotid Artery.
abstract: A 41-year-old man was admitted to our hospital because of a cancer-related stroke (CRS) caused by a thrombus of the extracranial carotid artery. He had undergone neoadjuvant radiochemotherapy for metastatic colorectal adenocarcinoma. The serum D-dimer values were within the normal range. We treated him with intravenous unfractionated heparin followed by warfarin. There were no recurrent stroke events over six months. The leading cause of a CRS is an embolism caused by hypercoagulopathy, mainly represented by non-bacterial thrombotic endocarditis. However, it was unusual that, in the current case, a thrombus of the extracranial carotid artery was formed with no significant residual stenosis, thus resulting in an artery-to-artery embolism.
authors.affiliation: Department of Neurology, Tohoku University School of Medicine, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Ando
authors.forename: Junpei
authors.initials: J
authors.lastname: Kobayashi
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Kuroda
authors.forename: Masashi
authors.initials: M
authors.lastname: Aoki
mesh_terms: D000328:Adult; D000925:Anticoagulants / Q000627:therapeutic use; D002339:Carotid Arteries / Q000473:pathology; D059186:Chemoradiotherapy, Adjuvant; D015179:Colorectal Neoplasms / Q000628:therapy; D005338:Fibrin Fibrinogen Degradation Products; D006801:Humans; D008297:Male; D009369:Neoplasms / Q000150:complications*; D020521:Stroke / Q000209:etiology*; D013927:Thrombosis / Q000150:complications*
chemical_list: D000925:Anticoagulants; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D