title: Role of implant configurations supporting three-unit fixed partial denture on mandibular bone response: biological-data-based finite element study.
abstract: Implant-supported fixed partial denture with cantilever extension can transfer the excessive load to the bone around implants and stress/strain concentration potentially leading to bone resorption. This study investigated the effects of implant configurations supporting three-unit fixed partial denture (FPD) on the stress and strain distribution in the peri-implant bone by combining clinically measured time-dependent loading data and finite element (FE) analysis. A 3-dimensional mandibular model was constructed based on computed tomography (CT) images. Four different configurations of implants supporting 3-unit FPDs, namely three implant-supported FPD, conventional three-unit bridge FPD, distal cantilever FPD and mesial cantilever FPD, were modelled. The FPDs were virtually inserted to the molar area in the mandibular FE models. The FPDs were loaded according to time-dependent in vivo-measured 3-dimensional loading data during chewing. The von Mises stress (VMS) and equivalent strain (EQS) in peri-implant bone regions were evaluated as mechanical stimuli. During the chewing cycles, the regions near implant necks and bottom apexes experienced high VMS and EQS than the middle regions in all implant-supported FPD configurations. Higher VMS and EQS values were also observed at the implant neck region adjacent to the cantilever extension in the cantilevered configurations. The patient-specific dynamic loading data and CT-based reconstruction of full 3D mandibular allowed us to model the biomechanical responses more realistically. The results provided data for clinical assessment of implant configuration to improve longevity and reliability of the implant-supported FPD restoration.
authors.affiliation: Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.|School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW, Australia.
authors.forename: N
authors.initials: N
authors.lastname: Yoda
authors.affiliation: School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW, Australia.
authors.forename: Z
authors.initials: Z
authors.lastname: Liao
authors.affiliation: Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, Potsdam, Germany.
authors.forename: J
authors.initials: J
authors.lastname: Chen
authors.affiliation: Division of Advanced Prosthetic Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
authors.forename: K
authors.initials: K
authors.lastname: Sasaki
authors.affiliation: Department of Bioclinical Sciences, Faculty of Dentistry, Kuwait University, Kuwait City, Kuwait.
authors.forename: M
authors.initials: M
authors.lastname: Swain
authors.affiliation: School of Aerospace, Mechanical and Mechatronic Engineering, The University of Sydney, Sydney, NSW, Australia.
authors.forename: Q
authors.initials: Q
authors.lastname: Li
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D001732:Bite Force; D000044:Dental Abutments; D015921:Dental Implants; D019094:Dental Prosthesis, Implant-Supported / Q000009:adverse effects* / Q000379:methods; D003799:Dental Stress Analysis; D003830:Denture, Partial, Fixed / Q000009:adverse effects*; D005260:Female; D020342:Finite Element Analysis; D006801:Humans; D021621:Imaging, Three-Dimensional; D008334:Mandible / Q000000981:diagnostic imaging / Q000473:pathology*; D015203:Reproducibility of Results; D013314:Stress, Mechanical; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome
chemical_list: D015921:Dental Implants
keywords: biomechanics; bite force; dental implant; finite element analysis; fixed partial denture; transducers