title: CLE peptides and their signaling pathways in plant development.
abstract: Cell-to-cell communication is crucial for the coherent functioning of multicellular organisms, and they have evolved intricate molecular mechanisms to achieve such communication. Small, secreted peptide hormones participate in cell-to-cell communication to regulate various physiological processes. One such family of plant peptide hormones is the CLAVATA3 (CLV3)/EMBRYO SURROUNDING REGION-related (CLE) family, whose members play crucial roles in the differentiation of shoot and root meristems. Recent biochemical and genetic studies have characterized various CLE signaling modules, which include CLE peptides, transmembrane receptors, and downstream intracellular signaling components. CLE signaling systems are conserved across the plant kingdom but have divergent modes of action in various developmental processes in different species. Moreover, several CLE peptides play roles in symbiosis, parasitism, and responses to abiotic cues. Here we review recent studies that have provided new insights into the mechanisms of CLE signaling.
authors.affiliation: Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan.
authors.forename: Yasuka L
authors.initials: YL
authors.lastname: Yamaguchi
authors.affiliation: Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan ishida@sci.kumamoto-u.ac.jp.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishida
authors.affiliation: Graduate School of Science and Technology, Kumamoto University, Kumamoto 860-8555, Japan.
authors.forename: Shinichiro
authors.initials: S
authors.lastname: Sawa
mesh_terms: D063245:Plant Development; D010937:Plant Growth Regulators / Q000235:genetics* / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D010937:Plant Growth Regulators; D010940:Plant Proteins
keywords: CLE peptide; Cell-to-cell communication; meristem; parasitism; root; shoot.