title: [EPIDEMIOLOGIC FEATURES OFNOROVIRUS INFECTION OUTBREAK IN THE REPUBLIC OF NORTH OSSETIA-ALANIA].
abstract: OBJECTIVE
  Analysis of epidemiologic features of a norovirus outbreak in Alagir city of the Republic of North Ossetia-Alania and effectiveness of measures of its liquidation.
  
  
  METHODS
  Data from maps-schemes of water supply system of Alagir city and statistical documentation of Centre of Hygiene and Epidemiology in the Republic of North Ossetia-Alania were used in the study. Indication of norovirus in clinical material and water samples was carried out bypolymerase chain reaction method.
  
  
  RESULTS
  Etiological agent of outbreak disease was established--genotype II norovirus. Realization of fecal-oral mechanisms of water transmission pathway of the causative agent of norovirus infection was detected. Conditions facilitating emergence and development of the indicated outbreak were determined--non-satisfactory sanitary-technical condition of water. supply system of the city.
  
  
  CONCLUSIONS
  The studied water outbreak of norovirus infection was caused by GII.17 genotype virus, that currently gradually displaces GII.IV genotype, and was characterized by an intensive start, involvement of all population age groups into the epidemic process (with primary infection of adults), low family focality, predominance of average severity disease forms in the clinical presentation. The counter-epidemic measures carried out ensured rapid localization and liquidation of the norovirus infection outbreak.
authors.forename: O V
authors.initials: OV
authors.lastname: Maletskaya
authors.forename: A G
authors.initials: AG
authors.lastname: Tibilov
authors.forename: D A
authors.initials: DA
authors.lastname: Prislegina
authors.forename: G K
authors.initials: GK
authors.lastname: Gazieva
authors.forename: N I
authors.initials: NI
authors.lastname: Otaraeva
authors.forename: A S
authors.initials: AS
authors.lastname: Volynkina
authors.forename: V N
authors.initials: VN
authors.lastname: Saveliev
authors.forename: G I
authors.initials: GI
authors.lastname: Lyamkin
authors.forename: A A
authors.initials: AA
authors.lastname: Zaitsev
authors.forename: A N
authors.initials: AN
authors.lastname: Kulichenko
mesh_terms: D017250:Caliciviridae Infections / Q000453:epidemiology* / Q000821:virology; D004196:Disease Outbreaks; D060766:Drinking Water / Q000821:virology*; D058872:Epidemics; D005243:Feces / Q000821:virology; D006801:Humans; D029322:Norovirus / Q000235:genetics / Q000302:isolation & purification / Q000472:pathogenicity*
chemical_list: D060766:Drinking Water