title: Agreement of anterior ocular biometric measurements with a new optical biometer and a Scheimpflug tomographer.
abstract: To evaluate the agreement between a new optical biometer (AL-Scan) and an anterior-segment Scheimpflug tomographer (Pentacam HR).
  
  
  
  Eye Hospital of Wenzhou Medical University, Zhejiang, China.
  
  
  
  Prospective randomized comparative case series.
  
  
  
  Three consecutive scans of the right eye of each subject were obtained using each device in a random order. The following common parameters were recorded: central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth, and keratometry (K) readings (steep, flat, and mean). Bland-Altman limits of agreement (LoA) were calculated for the common device parameters.
  
  
  
  The study comprised 121 healthy subjects (57 men, 64 women) with a mean age of 25.41 years ± 6.86 (SD) (range 18 to 54 years). The mean difference in CCT was 1.61 μm with LoA of -6.29 to 9.52 μm. The mean difference in the aqueous depth and ACD was 0.02 mm with LoA of -0.10 to 0.14 mm and -0.09 to 0.14 mm, respectively. For the 2.4 mm K readings from the new biometer versus the standard K readings from the Scheimpflug tomographer, the mean difference for flat K, steep K, and mean K was 0.10 diopter (D), 0.05 D, and 0.08 D, respectively. The LoA were -0.17 to 0.38 D, -0.29 to 0.39 D, and -0.19 to 0.34 D, respectively. The CCT, ACD, and all K readings were assessed to be clinically interchangeable.
  
  
  
  There was good agreement between the 2 devices for CCT, ACD, aqueous depth, and K readings.
  
  
  
  None of the authors has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Colm
authors.initials: C
authors.lastname: McAlinden
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Fangjun
authors.initials: F
authors.lastname: Bao
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Yan
authors.initials: Y
authors.lastname: Guo
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Xinxin
authors.initials: X
authors.lastname: Yu
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Weicong
authors.initials: W
authors.lastname: Lu
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Hao
authors.initials: H
authors.lastname: Chen
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia.
authors.forename: Qinmei
authors.initials: Q
authors.lastname: Wang
authors.affiliation: From the School of Ophthalmology and Optometry (McAlinden, Bao, Guo, Yu, Lu, Chen, Wang, Huang), Wenzhou Medical University, and the Key Laboratory of Vision Science (Bao, Lu, Chen, Wang, Huang), Ministry of Health P.R. China, Wenzhou, Zhejiang, China; the Abertawe Bro Morgannwg University Health Board (McAlinden), Swansea, United Kingdom; Flinders University (McAlinden), Adelaide, South Australia, Australia. Electronic address: vip999vip@163.com.
authors.forename: Jinhai
authors.initials: J
authors.lastname: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000867:Anterior Chamber; D001699:Biometry; D002681:China; D003315:Cornea / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D055095:Optics and Photonics; D011446:Prospective Studies; D015203:Reproducibility of Results; D055815:Young Adult