title: Amelanotic Irido-Ciliary Ring Melanoma: A Clinicopathological Correlation.
abstract: OBJECTIVE
  To report a case of an amelanotic irido-ciliary ring melanoma.
  
  
  METHODS
  Interventional case report.
  
  
  RESULTS
  A 44-year-old male was followed for asymptomatic amelanotic iris nevus of the right eye that was noted to have a localized ciliary body mass with ring extension along the trabecular meshwork. Fine needle aspiration biopsy was consistent with malignant melanoma. The patient underwent enucleation and remains disease free at 9 years of follow-up. Histopathology revealed malignant melanoma involving the iris and ciliary body with a 360-degree extension along the trabecular meshwork. The tumor was composed of a mixture of spindled and epithelioid cells with scant pigmentation.
  
  
  CONCLUSIONS
  Amelanotic irido-ciliary ring melanoma with growth along the trabecular meshwork is a rare form of uveal melanoma that could present as an inconspicuous amelanotic iris mass.
authors.affiliation: Department of Ophthalmology, Cole Eye Institute, Cleveland, Ohio, USA.
authors.forename: Hassan A
authors.initials: HA
authors.lastname: Aziz
authors.affiliation: Department of Ophthalmology, Cole Eye Institute, Cleveland, Ohio, USA.
authors.forename: Yasha S
authors.initials: YS
authors.lastname: Modi
authors.affiliation: Department of Pathology, Robert J. Tomsich Pathology and Laboratory Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.
authors.forename: Thomas P
authors.initials: TP
authors.lastname: Plesec
authors.affiliation: Department of Ophthalmology, Cole Eye Institute, Cleveland, Ohio, USA.
authors.forename: Arun D
authors.initials: AD
authors.lastname: Singh
keywords: Amelanotic irido-ciliary ring melanoma; Iris; Melanoma