title: [Primary Synovial Sarcoma in the Anterior Mediastinum;Report of a Case].
abstract: We report a rare case of synovial sarcoma in the anterior mediastinum. A 43-year-old man consulted our hospital with a complaint of dyspnea and chest discomfort. Chest computed tomography revealed an anterior mediastinal mass. Small open biopsy was performed, and the pathological examination revealed spindle-shaped cells with severe atypia. Tumor resection was performed. On pathology, fascicular and storiform patterns of spindle-shaped cells with severe atypia were noted. The tumor cells were positive for cytokeratin 7, vimentin, Bcl -2 and CD99, and the amplification of SYT-SSX fusion gene was also found. Therefore it was diagnosed as a synovial sarcoma.
authors.affiliation: Department of Diagnostic Pathology, Yamagata Prefectural Central Hospital, Yamagata, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Yanagawa
authors.forename: Satoshi
authors.initials: S
authors.lastname: Shiono
authors.forename: Masato
authors.initials: M
authors.lastname: Katahira
authors.forename: Mitsumasa
authors.initials: M
authors.lastname: Osakabe
authors.forename: Masami
authors.initials: M
authors.lastname: Abiko
authors.forename: Shinya
authors.initials: S
authors.lastname: Ogata
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000235:genetics; D001706:Biopsy; D006801:Humans; D008297:Male; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology*; D013584:Sarcoma, Synovial / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D014408:Biomarkers, Tumor