title: Hemorrhagic Descemet Membrane Detachment Following Syphilitic Interstitial Keratitis.
abstract: OBJECTIVE
  Syphilitic interstitial keratitis is a stromal inflammatory disease with characteristic secondary vascularization. This case illustrates a late complication of hemorrhagic Descemet membrane detachment.
  
  
  METHODS
  Case report.
  
  
  RESULTS
  The patient presented with painless sudden visual loss and progressive shallowing of the anterior chamber caused by hemorrhagic Descemet membrane detachment. She had corneal neovascularization and a positive syphilis serology. Owing to the risk of pupil block glaucoma, the patient had surgical drainage of the blood via an ab externo approach.
  
  
  CONCLUSIONS
  This case illustrates a previously unreported complication of syphilitic interstitial keratitis. The patient recovered good visual acuity and had residual pigment deposits in the pre-Descemet interface.
authors.affiliation: *Sydney Eye Hospital, Sydney, Australia; †University of the Witwatersrand, Johannesburg, South Africa; ‡Universiti Kebangsaan, Malaysia, Kuala Lumpur, Malaysia; and §Save Sight Institute, University of Sydney, Sydney, Australia.
authors.forename: Roland
authors.initials: R
authors.lastname: Höllhumer
authors.forename: Aida
authors.initials: A
authors.lastname: Zairani Mz
authors.forename: Stephanie
authors.initials: S
authors.lastname: Watson
mesh_terms: D000368:Aged; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000893:Anti-Inflammatory Agents / Q000627:therapeutic use; D002701:Chloramphenicol / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003316:Corneal Diseases / Q000175:diagnosis / Q000209:etiology*; D016510:Corneal Neovascularization / Q000175:diagnosis / Q000209:etiology / Q000628:therapy; D003320:Corneal Ulcer / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D003886:Descemet Membrane / Q000473:pathology*; D004359:Drug Therapy, Combination; D005130:Eye Hemorrhage / Q000175:diagnosis / Q000209:etiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D005260:Female; D006801:Humans; D009184:Mydriatics / Q000627:therapeutic use; D010656:Phenylephrine / Q000627:therapeutic use; D011239:Prednisolone / Q000031:analogs & derivatives / Q000627:therapeutic use; D013587:Syphilis / Q000175:diagnosis / Q000382:microbiology* / Q000628:therapy; D007507:Therapeutic Irrigation; D041623:Tomography, Optical Coherence; D014792:Visual Acuity
chemical_list: D000900:Anti-Bacterial Agents; D000893:Anti-Inflammatory Agents; D009184:Mydriatics; D010656:Phenylephrine; D002701:Chloramphenicol; C009935:prednisolone acetate; D011239:Prednisolone