title: Modulating the surface expression of cold receptors.
abstract: Temperature sensing is essential in every organism in order to adapt and survive. However, the mechanisms by which temperature is perceived and detected remain unclear. Recent findings on thermally-activated ion channels have shed light on the puzzle and unravel molecular entities for temperature detection and transduction in mammals.
authors.affiliation: Division of Neuroscience, Oregon National Primate Research Center; Oregon Health & Science University ; Beaverton, OR, USA.
authors.forename: Carlos A
authors.initials: CA
authors.lastname: Toro
authors.affiliation: Instituto de Fisiología; Facultad de Medicina; Universidad Austral de Chile ; Valdivia, Chile.
authors.forename: Sebastian
authors.initials: S
authors.lastname: Brauchi
keywords: AMPA, α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; PM, plasma membrane; TRP, transient receptor potential; TRPM8; TRPM8, Transient receptor potential cation channel subfamily M member 8; TRPV1, transient receptor potential cation channel subfamily V member 1; cold sensing; membrane dynamics; regulated exocytosis; signal amplification