title: Reaction of Paprika Carotenoids, Capsanthin and Capsorubin, with Reactive Oxygen Species.
abstract: The reaction of paprika carotenoids, capsanthin and capsorubin, with reactive oxygen species (ROS), such as superoxide anion radical (·O2(-)), hydroxyl radical (·OH), and singlet oxygen ((1)O2), was analyzed by LC/PDA ESI-MS and ESR spectrometry. Capsanthin formed both the 5,6-epoxide and 5,8-epoxide by reaction with ·O2(-) and ·OH. Furthermore, capsanthin also formed 5,6- and 5,8-endoperoxide on reaction with (1)O2. The same results were obtained in the case of capsanthin diacetate. On the other hand, capsorubin showed higher stability against these ROS. Capsorubin formed 7,8-epoxide on reaction with ·O2(-) and ·OH and 7,8-endoperoxide on reaction with (1)O2.
authors.affiliation: Institute of Health Sciences, Ezaki Glico Co., Ltd. , 4-6-5 Utajima, Nishiyodogawa-ku, Osaka 555-8502, Japan.
authors.forename: Azusa
authors.initials: A
authors.lastname: Nishino
authors.affiliation: Department of Analytical and Bioinorganic Chemistry, Division of Analytical and Physical Chemistry, Kyoto Pharmaceutical University , 5 Nakauchi-cho, Misasagi, Yamashina-ku, Kyoto 607-8414, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Yasui
authors.affiliation: Research Institute for Production Development , 15 Shimogamo, Morimoto Cho, Sakyoku, Kyoto 606-0805, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Maoka
mesh_terms: D002212:Capsicum / Q000737:chemistry; D004578:Electron Spin Resonance Spectroscopy; D004852:Epoxy Compounds / Q000737:chemistry; D017665:Hydroxyl Radical / Q000737:chemistry; D017382:Reactive Oxygen Species / Q000737:chemistry*; D013481:Superoxides / Q000737:chemistry; D024341:Xanthophylls / Q000737:chemistry*
chemical_list: D004852:Epoxy Compounds; D017382:Reactive Oxygen Species; D024341:Xanthophylls; D013481:Superoxides; D017665:Hydroxyl Radical; C006889:capsanthin; C035624:capsorubin
keywords: capsanthin; capsanthin endoperoxide; capsanthin epoxide; capsorubin; reactive oxygen species