title: Glucose intolerance in dairy goats with pregnancy toxemia: Lack of correlation between blood pH and beta hydroxybutyric acid values.
abstract: This study assessed the response to a glucose tolerance test in dairy goats with pregnancy toxemia (PT), in healthy, pregnant, non-lactating dairy goats in the last month of gestation (HP), and in healthy, lactating, non-pregnant, dairy goats in mid-lactation (HL). A 500 mL volume of a 5% glucose solution was administered by the IV route. Blood glucose concentrations returned to pre-infusion levels by 90 min in all 8 HL goats, and by 180 min in all 8 HP goats. In contrast, concentrations of blood glucose were still significantly above pre-infusion levels at 180 min post-infusion in all 8 PT goats. Thus, marked glucose intolerance was demonstrated in the PT goats, and mild intolerance was noted in the HP goats. In 25 goats diagnosed with PT and having blood beta hydroxybutyric acid (BHBA) values ≥ 2.9 mmol/L, the correlation coefficient for BHBA with blood pH was non-significant.
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: Miguel S
authors.initials: MS
authors.lastname: Lima
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: João B
authors.initials: JB
authors.lastname: Cota
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: Yolanda M
authors.initials: YM
authors.lastname: Vaz
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: Inês G
authors.initials: IG
authors.lastname: Ajuda
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: Rita A
authors.initials: RA
authors.lastname: Pascoal
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: Nuno
authors.initials: N
authors.lastname: Carolino
authors.affiliation: Faculdade de Medicina Veterinária, CIISA, DC, Universidade de Lisboa, Portugal (Lima, Cota, Vaz, Ajuda); Barão e Barão, Coutada Velha, Benavente, Portugal (Pascoal); INIAV, EUVG, CIISA, Portugal (Carolino); School of Veterinary Medicine, University of California, Davis, California 95616, USA (Hjerpe).
authors.forename: Charles A
authors.initials: CA
authors.lastname: Hjerpe
mesh_terms: D020155:3-Hydroxybutyric Acid / Q000097:blood*; D000818:Animals; D005260:Female; D018149:Glucose Intolerance / Q000097:blood / Q000662:veterinary*; D015511:Goat Diseases / Q000097:blood*; D006041:Goats; D006863:Hydrogen-Ion Concentration; D011225:Pre-Eclampsia / Q000097:blood / Q000662:veterinary*; D011247:Pregnancy
chemical_list: D020155:3-Hydroxybutyric Acid