title: Best sensitivity of18F-FDOPA PET/CT to detect metastasis in one case of neuroendocrine tumour of the ileum.
abstract: Neuroendocrine tumours (NET) are heterogeneous and frequently spread over the body, making their imaging difficult. With this aim, nuclear medicine imaging, using PET or SPECT with different tracers, has been proposed for decades, but there is currently no consensus on the most appropriate technique, even when only considering gastrointestinal NET. The case is presented of a 67year old woman with a well differentiated NET of the ileum with suspected recurrence, which was not detected by any imaging technique except18F-FDOPA PET/CT. Subsequent follow up showed disease progression, which confirmed the true positivity of18F-FDOPA. Using this case, we discuss and compare different radiotracers for the diagnosis of gastrointestinal NET, focusing on those embryologically originating from the mid-gut.
authors.affiliation: Servicio de Medicina Nuclear, Hôpital Tenon AP-HP et Université P & Marie Curie, París, Francia; Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Granada, Granada, España. Electronic address: nathalietestart@gmail.com.
authors.forename: N
authors.initials: N
authors.lastname: Testart Dardel
authors.affiliation: Servicio de Medicina Nuclear, Hôpital Tenon AP-HP et Université P & Marie Curie, París, Francia.
authors.forename: F
authors.initials: F
authors.lastname: Montravers
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario Universitario de Granada, Granada, España.
authors.forename: E
authors.initials: E
authors.lastname: Triviño-Ibañez
authors.affiliation: Servicio de Medicina Nuclear, Hôpital Tenon AP-HP et Université P & Marie Curie, París, Francia.
authors.forename: M
authors.initials: M
authors.lastname: Gauthé
authors.affiliation: Servicio de Cirugía, Hôpital Tenon AP-HP et Université P & Marie Curie, París, Francia.
authors.forename: S
authors.initials: S
authors.lastname: Houry
authors.affiliation: Servicio de Medicina Nuclear, Hôpital Tenon AP-HP et Université P & Marie Curie, París, Francia.
authors.forename: J N
authors.initials: JN
authors.lastname: Talbot
mesh_terms: D000368:Aged; D004295:Dihydroxyphenylalanine / Q000031:analogs & derivatives*; D005260:Female; D005462:Fluorine Radioisotopes; D006801:Humans; D007078:Ileal Neoplasms / Q000473:pathology*; D018358:Neuroendocrine Tumors / Q000000981:diagnostic imaging* / Q000556:secondary*; D000072078:Positron Emission Tomography Computed Tomography; D012680:Sensitivity and Specificity
chemical_list: D005462:Fluorine Radioisotopes; C043437:fluorodopa F 18; D004295:Dihydroxyphenylalanine
keywords: (18)F-FDOPA; (68)Ga-DOTATOC; Neuroendocrine Tumours; PET/CT; PET/TC; Tumores Neuroendocrinos