title: The importance of systematic approaches in the study of emesis.
abstract: Nausea and vomiting are among the most basic of human experiences and unfortunately accompany a wide variety of clinical treatments as side effects. Despite decades of research, the neural mechanisms of nausea and vomiting (emesis) remain elusive. TRPV1 represents a possibly overlooked and understudied pharmacological target with anti-emetic potential.
authors.affiliation: University of Pennsylvania; School of Nursing; Department of Biobehavioral Health Sciences ; Philadelphia, PA USA.
authors.forename: Bart C
authors.initials: BC
authors.lastname: De Jonghe
authors.affiliation: University of Pittsburgh Cancer Institute ; Pittsburgh, PA USA.
authors.forename: Charles C
authors.initials: CC
authors.lastname: Horn
keywords: RTX; Suncus murinus; anti-emetic; capsaicin; ferret; nausea; translational drug development; vanilloid; vomiting