title: [Administration of Palonosetron and Phenotropil for Prophylaxis of the N-V-D Stage of Acute Radiation Syndrome].
abstract: Experiments on small (rats) and large (dogs) animals have shown that a sequential administration of Palonosetron and Phenotropil decreases the intensity of the main manifestations of the N-V-D stage of acute radiation syndrome. These data show the appropriateness of a combined administration of Palonosetron and Phenotropil to prevent a reduced work capacity in the individuals participating in elimination of the consequences of accidents associated with overexposure to radiation.
authors.forename: I S
authors.initials: IS
authors.lastname: Drachouv
authors.forename: V N
authors.initials: VN
authors.lastname: Bykov
authors.forename: A B
authors.initials: AB
authors.lastname: Seleznev
mesh_terms: D054508:Acute Radiation Syndrome / Q000503:physiopathology / Q000517:prevention & control*; D000818:Animals; D004285:Dogs; D004338:Drug Combinations; D005720:Gamma Rays / Q000009:adverse effects; D006801:Humans; D007546:Isoquinolines / Q000008:administration & dosage*; D000077924:Palonosetron; D010889:Piracetam / Q000008:administration & dosage / Q000031:analogs & derivatives*; D011812:Quinuclidines / Q000008:administration & dosage*; D051381:Rats
chemical_list: D004338:Drug Combinations; D007546:Isoquinolines; D011812:Quinuclidines; D000077924:Palonosetron; C037917:4-phenylpiracetam; D010889:Piracetam