title: Differentiation between Phyllodes Tumors and Fibroadenomas Based on Mammographic Sonographic and MRI Features.
abstract: BACKGROUND
  This study was performed to compare the mammographic, sonographic, and magnetic resonance imaging (MRI) characteristics of phyllodes tumors and fibroadenomas, which may resemble each other.
  
  
  METHODS
  Preoperative mammograms, B-mode and Doppler sonograms, and dynamic breast MRIs of 72 patients with pathologically proven fibroadenomas and 70 patients with pathologically proven phyllodes tumor were evaluated in this retrospective study. Statistical significance was evaluated using chi-square and Fisher's exact tests. Correlations in lesion size among radiological methods were examined by Pearson's correlation analysis.
  
  
  RESULTS
  The features that differed on mammogram were size, shape, and margin of the mass. Sonograms showed significant differences in size, shape, margin, echo pattern, and vascularization of the mass. Pearson's correlation analysis showed strong agreement among radiological methods in terms of assessment of size. Tumor size ≥ 3 cm, irregular shape, microlobulated margins, complex internal echo pattern, and hypervascularity were significant findings of phyllodes tumors. Internal cystic areas on MRI were frequently associated with phyllodes tumors.
  
  
  CONCLUSIONS
  Mammographic, sonographic, and MRI findings of fibroadenomas and phyllodes tumors could help radiologists to ascertain imaging-histological concordance and guide clinicians in their decision making regarding adequate follow-up or the necessity of biopsy.
authors.affiliation: Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Lale
authors.initials: L
authors.lastname: Duman
authors.affiliation: Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Naciye S
authors.initials: NS
authors.lastname: Gezer
authors.affiliation: Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Pınar
authors.initials: P
authors.lastname: Balcı
authors.affiliation: Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Canan
authors.initials: C
authors.lastname: Altay
authors.affiliation: Department of Radiology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Işıl
authors.initials: I
authors.lastname: Başara
authors.affiliation: Department of Pathology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Merih G
authors.initials: MG
authors.lastname: Durak
authors.affiliation: Department of General Surgery, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Ali I
authors.initials: AI
authors.lastname: Sevinç
keywords: Differential diagnosis; Fibroadenoma; Phyllodes tumor