title: A highly selective and sensitive photoinduced electron transfer (PET) based HOCl fluorescent probe in water and its endogenous imaging in living cells.
abstract: A probe based on the phenothiazine-acridine orange conjugate (Ptz-AO) has been designed and synthesized for the sensitive and selective detection of HOCl. Ptz-AO has excellent properties, including pH-independence of fluorescence, high resistance to photobleaching, and response in real time. The value of Ptz-AO was confirmed by exogenous, endogenous and the real-time imaging of HOCl in vitro using a fluorescence microscope.
authors.affiliation: School of Materials Science and Engineering, Harbin Institute of Technology, Harbin 150001, China.
authors.forename: Lijuan
authors.initials: L
authors.lastname: Liang
authors.forename: Chang
authors.initials: C
authors.lastname: Liu
authors.forename: Xiaojie
authors.initials: X
authors.lastname: Jiao
authors.forename: Liancheng
authors.initials: L
authors.lastname: Zhao
authors.forename: Xianshun
authors.initials: X
authors.lastname: Zeng
mesh_terms: D000818:Animals; D002460:Cell Line; D004579:Electron Transport; D005456:Fluorescent Dyes / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D006997:Hypochlorous Acid / Q000737:chemistry*; D051379:Mice; D008856:Microscopy, Fluorescence; D015394:Molecular Structure; D061848:Optical Imaging; D055668:Photochemical Processes; D013997:Time Factors; D014867:Water / Q000737:chemistry
chemical_list: D005456:Fluorescent Dyes; D014867:Water; D006997:Hypochlorous Acid