title: Programming Self-Assembly of DNA Origami Honeycomb Two-Dimensional Lattices and Plasmonic Metamaterials.
abstract: Scaffolded DNA origami has proven to be a versatile method for generating functional nanostructures with prescribed sub-100 nm shapes. Programming DNA-origami tiles to form large-scale 2D lattices that span hundreds of nanometers to the micrometer scale could provide an enabling platform for diverse applications ranging from metamaterials to surface-based biophysical assays. Toward this end, here we design a family of hexagonal DNA-origami tiles using computer-aided design and demonstrate successful self-assembly of micrometer-scale 2D honeycomb lattices and tubes by controlling their geometric and mechanical properties including their interconnecting strands. Our results offer insight into programmed self-assembly of low-defect supra-molecular DNA-origami 2D lattices and tubes. In addition, we demonstrate that these DNA-origami hexagon tiles and honeycomb lattices are versatile platforms for assembling optical metamaterials via programmable spatial arrangement of gold nanoparticles (AuNPs) into cluster and superlattice geometries.
authors.affiliation: Wallance H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University , Atlanta, Georgia 30322, United States.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Wang
authors.affiliation: Department of Biological Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.
authors.forename: Stavros
authors.initials: S
authors.lastname: Gaitanaros
authors.affiliation: SKKU Advanced Institute of Nanotechnology & School of Chemical Engineering, Sungkyunkwan University (SKKU) , Suwon, 16419, Republic of Korea.
authors.forename: Seungwoo
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Biological Engineering, Massachusetts Institute of Technology , Cambridge, Massachusetts 02139, United States.
authors.forename: Mark
authors.initials: M
authors.lastname: Bathe
authors.affiliation: Wyss Institute for Biologically Inspired Engineering and Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Harvard University , Boston, Massachusetts 02115, United States.
authors.forename: William M
authors.initials: WM
authors.lastname: Shih
authors.affiliation: Wallance H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University , Atlanta, Georgia 30322, United States.
authors.forename: Yonggang
authors.initials: Y
authors.lastname: Ke
mesh_terms: D016000:Cluster Analysis; D017076:Computer-Aided Design; D004247:DNA / Q000737:chemistry*; D006046:Gold / Q000737:chemistry; D008422:Materials Testing; D053768:Metal Nanoparticles / Q000737:chemistry*; D018625:Microscopy, Atomic Force; D046529:Microscopy, Electron, Transmission; D008962:Models, Theoretical; D049329:Nanostructures / Q000737:chemistry; D036103:Nanotechnology; D009690:Nucleic Acid Conformation; D012984:Software; D013314:Stress, Mechanical
chemical_list: D006046:Gold; D004247:DNA