title: Efficacy of probiotics as an adjuvant agent in eradication of Helicobacter pylori infection and associated side effects.
abstract: The intestinal tract is a host to various types of bacteria that are essential to health. Interactions between intestinal bacteria, i.e. the normal microbiota of the host's intestine, have been a subject of intensive research, as they may influence disease cycles. Recent studies of selected probiotic species and their therapeutic benefits have suggested a potential efficacy in treatment of several gastrointestinal illnesses, including Helicobacter pylori infection. The increasing evidence from these clinical studies supports the promising role of probiotics in improving the treatment of H. pylori by increasing eradication rates as well as decreasing the adverse effects of current medication therapy. However, many unsolved questions remain which require high quality trials on specific probiotic strains in the future. The main part of this review will focus on the effects of supplementary probiotic products during standard triple H. pylori therapy.
authors.affiliation: 1 Department of Biological Sciences, Neurobiology and Physiology, University of Maryland, College Park, MD 20742, USA.
authors.forename: Y Dasteh
authors.initials: YD
authors.lastname: Goli
authors.affiliation: 2 Department of Microbiology and Immunology, Anatomical Sciences Research Center, Kashan University of Medical Sciences, 87154 Kashan, Iran.
authors.forename: R
authors.initials: R
authors.lastname: Moniri
mesh_terms: D000818:Animals; D016481:Helicobacter Infections / Q000178:diet therapy*; D016480:Helicobacter pylori; D006801:Humans; D019936:Probiotics / Q000008:administration & dosage / Q000627:therapeutic use*
keywords: Helicobacter pylori; eradication; infection; probiotics; side effect