title: Pseudotumour formation and subsequent resolution in metal-on-metal total hip arthroplasty following revision: Instructional review and an illustrative case report with revision using a dual mobility design.
abstract: The use of large-diameter metal-on-metal (MoM) components in total hip arthroplasty (THA) is associated with an increased risk of early failure due to adverse local tissue reaction to metal debris (ARMD) in response to the release of metal ions from the bearing couple and/or head-neck taper corrosion. The aim of this paper was to present a review of the incidence and natural history of ARMD and the forms of treatment, with a focus on the need for and extent of resection or debulking of the pseudotumour. An illustrative case report is presented of a patient with an intra-pelvic pseudotumour associated with a large diameter MoM THA, which was treated successfully with revision of the bearing surface to a dual mobility couple and retention of the well-fixed acetabular and femoral components. The pseudotumour was left in situ Resolution of the intra-pelvic mass and normalisation of metal ion levels was observed seven months post-operatively. Cite this article: Bone Joint J 2016;98-B:736-40.
authors.affiliation: University of Washington, 1959 NE Pacific St, Seattle, WA, 98195, USA.
authors.forename: A A
authors.initials: AA
authors.lastname: Sassoon
authors.affiliation: Washington University, 4921 Parkview Place, St. Louis, MO 63110, USA.
authors.forename: R L
authors.initials: RL
authors.lastname: Barrack
mesh_terms: D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D001799:Blood Sedimentation; D002097:C-Reactive Protein / Q000032:analysis; D002857:Chromium / Q000097:blood; D003035:Cobalt / Q000097:blood; D006104:Granuloma, Plasma Cell / Q000209:etiology* / Q000601:surgery*; D006801:Humans; D008297:Male; D061825:Metal-on-Metal Joint Prostheses / Q000009:adverse effects*; D012086:Reoperation
chemical_list: D002857:Chromium; D003035:Cobalt; D002097:C-Reactive Protein
keywords: Corrosion; Metal-on-Metal; Pseudotumour; Revision Total Hip Arthroplasty