title: Follicular Dendritic Cell Sarcoma of Appendix Presenting as Acute Appendicitis: An Exceptionally Rare Case Report.
abstract: Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm that originates from dendritic cells of lymphoid follicles and shows low to intermediate malignant potential. It most commonly arises from lymph nodes, but may originate from a variety of extranodal sites. FDCS of appendix is exceptionally rare, and only a single case has been reported. Herein, we describe the clincopathological features of a case of FDCS originating from appendix with emphasis on being able to recognize this rare neoplasm in the context of the differential diagnosis of more common intraabdominal spindle cell tumors.
authors.affiliation: Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Arsalan
authors.initials: A
authors.lastname: Ahmed
authors.affiliation: Aga Khan University Hospital, Karachi, Pakistan nasir.uddin@aku.edu.
authors.forename: Nasir
authors.initials: N
authors.lastname: Ud Din
authors.affiliation: Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Abdur Rehman
authors.initials: AR
authors.lastname: Alvi
authors.affiliation: Cleveland Clinic, Cleveland, OH, USA.
authors.forename: Brian P
authors.initials: BP
authors.lastname: Rubin
mesh_terms: D001063:Appendiceal Neoplasms / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D001064:Appendicitis / Q000209:etiology*; D014408:Biomarkers, Tumor / Q000032:analysis; D054740:Dendritic Cell Sarcoma, Follicular / Q000150:complications / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008875:Middle Aged
chemical_list: D014408:Biomarkers, Tumor
keywords: appendix; follicular dendritic cell sarcoma; immunohistochemistry; spindle cell neoplasm