title: Sarcoma-Like Mural Nodule in a Borderline Mucinous Tumour of Ovary.
abstract: A 37-year female presented with complaint of lower abdominal pain and amenorrhoea to the Military Hospital, Rawalpindi. Ultrasound of pelvis showed a right adnexal cystic lesion. On investigation, CA-125 was raised. Her MRI scan of pelvis revealed a right adnexal mass of fluid intensity measuring 15.2 x 12.9 x 9.2 cm. Right ovarian cystectomy was performed and the specimen was sent for histopathological examination. Grossly, the mass was cystic in appearance and measured 13.5 x 10 x 10 cm. On sectioning, it was unilocular and filled with turbid material. The cyst wall showed multiple papillary structures along with a nodule measuring 1.1 x 1 cm. Microscopically, the sections revealed borderline mucinous tumour with a sarcoma-like mural nodule composed of spindle shaped cells and epulis-like giant cells. Sarcoma-like mural nodules are rare nodules which are associated with mucinous tumours of the ovary. However, they have excellent prognosis and should not be interpreted as malignant.
authors.affiliation: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi.
authors.forename: Rabia
authors.initials: R
authors.lastname: Ahmed
authors.affiliation: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi.
authors.forename: Hafeez Ud
authors.initials: HU
authors.lastname: Din
authors.affiliation: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi.
authors.forename: Shoaib Naiyar
authors.initials: SN
authors.lastname: Hashmi
authors.affiliation: Department of Histopathology, Armed Forces Institute of Pathology, Rawalpindi.
authors.forename: Iqbal
authors.initials: I
authors.lastname: Muhammad
mesh_terms: D000328:Adult; D000568:Amenorrhea / Q000209:etiology; D018394:CA-125 Antigen / Q000097:blood; D018291:Cystadenoma, Mucinous / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D015653:Cystectomy; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D010051:Ovarian Neoplasms / Q000145:classification / Q000175:diagnosis* / Q000473:pathology; D010388:Pelvis / Q000000981:diagnostic imaging*; D012509:Sarcoma / Q000473:pathology*
chemical_list: D018394:CA-125 Antigen