title: Human Embryonic Stem Cells: A Model for the Study of Neural Development and Neurological Diseases.
abstract: Although the mechanism of neurogenesis has been well documented in other organisms, there might be fundamental differences between human and those species referring to species-specific context. Based on principles learned from other systems, it is found that the signaling pathways required for neural induction and specification of human embryonic stem cells (hESCs) recapitulated those in the early embryo development in vivo at certain degree. This underscores the usefulness of hESCs in understanding early human neural development and reinforces the need to integrate the principles of developmental biology and hESC biology for an efficient neural differentiation.
authors.affiliation: School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
authors.forename: Piya
authors.initials: P
authors.lastname: Prajumwongs
authors.affiliation: School of Anatomy, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
authors.forename: Oratai
authors.initials: O
authors.lastname: Weeranantanapan
authors.affiliation: School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
authors.forename: Thiranut
authors.initials: T
authors.lastname: Jaroonwitchawan
authors.affiliation: School of Biotechnology, Institute of Agricultural Technology, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
authors.forename: Parinya
authors.initials: P
authors.lastname: Noisa