title: Structural Characterization of Lecithin-Stabilized Tetracosane Lipid Nanoparticles. Part I: Emulsions.
abstract: The structure of 1,2-dimyristoyl-sn-glycero-3-phosphocholine (DMPC)-stabilized colloidal tetracosane emulsions was investigated by photon correlation spectroscopy and small-angle X-ray and neutron scattering, using emulsions with different neutron scattering contrasts. Special emphasis was placed on the structure of the DMPC stabilizer layer covering the emulsion droplets. A monolayer, structurally similar to a half DMPC bilayer, with a thickness of 16 Å is found. Thereby, the phosphocholine headgroups arrange flat at the oil-water interface. A deep penetration of the tetracosane oil into the stabilizer layer can be ruled out.
authors.affiliation: Professur für Nanomaterialcharakterisierung (Streumethoden), Friedrich-Alexander-Universität Erlangen-Nürnberg , Staudtstr. 3, 91058 Erlangen, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Schmiele
authors.affiliation: German Engineering Materials Science Centre (GEMS) at Heinz Maier-Leibnitz Zentrum (MLZ), Helmholtz-Zentrum Geesthacht GmbH , Lichtenbergstr. 1, 85747 Garching, Germany.
authors.forename: S
authors.initials: S
authors.lastname: Busch
authors.affiliation: Heinz Maier-Leibnitz Zentrum (MLZ), Technische Universität München , Lichtenbergstr. 1, 85747 Garching, Germany.
authors.forename: H
authors.initials: H
authors.lastname: Morhenn
authors.affiliation: Professur für Nanomaterialcharakterisierung (Streumethoden), Friedrich-Alexander-Universität Erlangen-Nürnberg , Staudtstr. 3, 91058 Erlangen, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Schindler
authors.affiliation: Professur für Nanomaterialcharakterisierung (Streumethoden), Friedrich-Alexander-Universität Erlangen-Nürnberg , Staudtstr. 3, 91058 Erlangen, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Schmutzler
authors.affiliation: DS/LSS, Institut Laue-Langevin (ILL) , 71 Avenue des Martyrs, CS20156, 38042 Grenoble CEDEX 9, France.
authors.forename: R
authors.initials: R
authors.lastname: Schweins
authors.affiliation: DS/LSS, Institut Laue-Langevin (ILL) , 71 Avenue des Martyrs, CS20156, 38042 Grenoble CEDEX 9, France.
authors.forename: P
authors.initials: P
authors.lastname: Lindner
authors.affiliation: European Synchrotron Radiation Facility (ESRF) , 71 Avenue des Martyrs, CS40220, 38042 Grenoble CEDEX 9, France.
authors.forename: P
authors.initials: P
authors.lastname: Boesecke
authors.affiliation: Center for Electron Microscopy of the Jena University Hospital , Ziegelmühlenweg 1, 07743 Jena, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Westermann
authors.affiliation: Center for Electron Microscopy of the Jena University Hospital , Ziegelmühlenweg 1, 07743 Jena, Germany.
authors.forename: F
authors.initials: F
authors.lastname: Steiniger
authors.affiliation: HASYLAB , Notkestr. 85, 22603 Hamburg, Germany.
authors.forename: Sérgio S
authors.initials: SS
authors.lastname: Funari
authors.affiliation: Professur für Nanomaterialcharakterisierung (Streumethoden), Friedrich-Alexander-Universität Erlangen-Nürnberg , Staudtstr. 3, 91058 Erlangen, Germany.
authors.forename: T
authors.initials: T
authors.lastname: Unruh