title: Initial management and outcomes after superficial thrombophlebitis: The Cardiovascular Research Network Venous Thromboembolism study.
abstract: Although superficial thrombophlebitis (SVTE) is generally considered a benign, self-limited disease, accumulating evidence suggests that it often leads to more serious forms of venous thromboembolism. We reviewed the medical charts of 329 subjects with SVTE from the Cardiovascular Research Network Venous Thromboembolism cohort study to collect information on the acute treatment of SVTE and subsequent diagnosis of deep venous thrombosis within 1 year. All participants received care within Kaiser Permanente Northern California, a large, integrated healthcare delivery system. Fourteen (4.3%) subjects with SVTE received anticoagulants, 148 (45.0%) were recommended antiplatelet agents or nonsteroidal anti-inflammatory drugs, and in 167 (50.8%) there was no documented antithrombotic therapy. In the year after SVTE diagnosis, 19 (5.8%) patients had a subsequent diagnosis of a deep venous thrombosis or pulmonary embolism. In conclusion, clinically significant venous thrombosis within a year after SVTE was uncommon in our study despite infrequent use of antithrombotic therapy. Journal of Hospital Medicine 2016;11:432-434. © 2016 Society of Hospital Medicine.
authors.affiliation: Division of Hematology-Oncology, University of Washington, Fred Hutchinson Cancer Research Center, Seattle, Washington.
authors.forename: Bethany
authors.initials: B
authors.lastname: Samuelson
authors.affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, California.|Departments of Epidemiology, Biostatistics, and Medicine, University of California, San Francisco, San Francisco, California, and Department of Health Research and Policy, Stanford University School of Medicine, Palo Alto, California.
authors.forename: Alan S
authors.initials: AS
authors.lastname: Go
authors.affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, California.
authors.forename: Sue Hee
authors.initials: SH
authors.lastname: Sung
authors.affiliation: Division of Research, Kaiser Permanente Northern California, Oakland, California.
authors.forename: Dongjie
authors.initials: D
authors.lastname: Fan
authors.affiliation: Division of Hospital Medicine, University of California, San Francisco, San Francisco, California.
authors.forename: Margaret C
authors.initials: MC
authors.lastname: Fang
mesh_terms: D000925:Anticoagulants / Q000627:therapeutic use; D002140:California; D019468:Disease Management; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D011655:Pulmonary Embolism / Q000209:etiology; D012189:Retrospective Studies; D013924:Thrombophlebitis / Q000150:complications / Q000188:drug therapy; D054556:Venous Thromboembolism / Q000209:etiology*
chemical_list: D000925:Anticoagulants; D010975:Platelet Aggregation Inhibitors