title: The Prevalence of Open-Angle Glaucoma by Age in Myopia: The Korea National Health and Nutrition Examination Survey.
abstract: To investigate the prevalence of open-angle glaucoma (OAG) in myopia by age.
  
  
  
  A cross-sectional study using a stratified, multistage, probability cluster survey. Participants in the Korean National Health and Nutrition Examination Survey between 2010 and 2011 were included. A standardized protocol was used to interview every participant and perform comprehensive ophthalmic examinations. Glaucoma was diagnosed according to the International Society of Geographical and Epidemiological Ophthalmology (ISGEO) criteria.
  
  
  
  After adjusting for age and sex, there was a positive correlation between OAG prevalence and increasing myopic refractive error except in participants with hyperopia. Younger participants with higher myopic refractive error had higher OAG prevalence than older participants with lower myopic refractive error. Participants with high myopia (OR 3.90, 95% confidence interval (CI) 2.30-6.59) had significantly greater age- and sex-adjusted odd ratios (ORs) than did those with emmetropia who were younger than 60 years.
  
  
  
  These data suggest that OAG develops earlier in participants with high myopia than in others. There was a high prevalence of OAG in participants with high myopia, even in those 19-29 years of age. Therefore, OAG screening should be performed earlier in participants with high myopia than is suggested by traditional guidelines.
authors.affiliation: a Department of Ophthalmology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Korea.
authors.forename: Seong Hee
authors.initials: SH
authors.lastname: Shim
authors.affiliation: b Department of Ophthalmology , Asan Medical Center, University of Ulsan College of Medicine , Seoul , Korea.
authors.forename: Kyung Rim
authors.initials: KR
authors.lastname: Sung
authors.affiliation: a Department of Ophthalmology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Korea.
authors.forename: Joon Mo
authors.initials: JM
authors.lastname: Kim
authors.affiliation: a Department of Ophthalmology , Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine , Seoul , Korea.
authors.forename: Hyun Tae
authors.initials: HT
authors.lastname: Kim
authors.affiliation: c Department of Ophthalmology , Jeju National University Hospital , Jeju , Korea.
authors.forename: Jinho
authors.initials: J
authors.lastname: Jeong
authors.affiliation: d Department of Ophthalmology , Institute of Vision Research, Yonsei University College of Medicine , Seoul , Republic of Korea.
authors.forename: Chan Yun
authors.initials: CY
authors.lastname: Kim
authors.affiliation: e Department of Biostatistics , Kangbuk Samsung Hospital , Seoul , Korea.
authors.forename: Mi Yeon
authors.initials: MY
authors.lastname: Lee
authors.affiliation: f Department of Ophthalmology , Seoul National University College of Medicine, Seoul National University Hospital , Seoul , Korea.
authors.forename: Ki Ho
authors.initials: KH
authors.lastname: Park
mesh_terms: D000328:Adult; D017677:Age Distribution; D003430:Cross-Sectional Studies; D005260:Female; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000175:diagnosis / Q000453:epidemiology* / Q000503:physiopathology; D009749:Nutrition Surveys / Q000706:statistics & numerical data*; D015995:Prevalence; D056910:Republic of Korea / Q000453:epidemiology; D017678:Sex Distribution; D055815:Young Adult
keywords: Glaucoma; high myopia; myopia; screening; young age