title: [Giant cell aortitis complicated by AA amyloidosis diagnosed with imaging techniques: Report of a case].
abstract: BACKGROUND
  AA amyloidosis is a common but severe complication of many chronic inflammatory processes of infectious, autoimmune, or neoplastic origin. It frequently leads to renal damage, often presenting as a nephrotic syndrome. Giant cell arteritis is a common inflammatory arteritis in elderly people, but rarely complicated by AA amyloidosis.
  
  
  METHODS
  We report an 87-year-old female who presented with a nephrotic syndrome and a chronic inflammation, in whom the kidney biopsy showed secondary amyloidosis. Etiological investigations concluded an amyloidosis related to giant cell pan-aortitis, whereas there were no typical clinical signs for this diagnosis. Outcome was rapidly unfavourable despite the treatment.
  
  
  CONCLUSIONS
  In case of chronic inflammation of unknown origin in elderly patients, aortitis complicating a giant cell arteritis should be looked for with imaging techniques, as clinical diagnosis of this presentation is difficult, whereas delayed diagnosis exposes to severe or fatal issues.
authors.affiliation: Service de néphrologie et dialyse, centre hospitalier de Douai, route de Cambrai, 59507 Douai, France. Electronic address: jeanphilippe.hammelin@ch-douai.fr.
authors.forename: J-P
authors.initials: JP
authors.lastname: Hammelin
authors.affiliation: Service de néphrologie et dialyse, centre hospitalier de Douai, route de Cambrai, 59507 Douai, France.
authors.forename: G
authors.initials: G
authors.lastname: Cardon
authors.affiliation: Service de néphrologie et dialyse, centre hospitalier de Douai, route de Cambrai, 59507 Douai, France.
authors.forename: M
authors.initials: M
authors.lastname: Reberolle
authors.affiliation: Service de néphrologie et dialyse, centre hospitalier de Douai, route de Cambrai, 59507 Douai, France.
authors.forename: F
authors.initials: F
authors.lastname: Moulonguet
authors.affiliation: Service de néphrologie et dialyse, centre hospitalier de Douai, route de Cambrai, 59507 Douai, France.
authors.forename: Y
authors.initials: Y
authors.lastname: Neugebauer
authors.affiliation: Service de cardiologie et explorations fonctionnelles, centre hospitalier de Douai, 59507 Douai, France.
authors.forename: G
authors.initials: G
authors.lastname: Raybaud
authors.affiliation: Institut de pathologie-anatomie et cytologie pathologiques, CHRU de Lille, 59000 Lille, France.
authors.forename: V
authors.initials: V
authors.lastname: Gnemmi
authors.affiliation: Service de médecine interne, hôpital Claude-Huriez, CHRU de Lille, 59000 Lille, France.
authors.forename: E
authors.initials: E
authors.lastname: Hachulla
mesh_terms: D000369:Aged, 80 and over; D000686:Amyloidosis / Q000150:complications / Q000175:diagnosis*; D001025:Aortitis / Q000150:complications / Q000175:diagnosis; D003952:Diagnostic Imaging; D005260:Female; D013700:Giant Cell Arteritis / Q000150:complications / Q000175:diagnosis*; D006801:Humans; D007674:Kidney Diseases / Q000150:complications / Q000175:diagnosis*; D009404:Nephrotic Syndrome / Q000150:complications / Q000175:diagnosis
keywords: Amyloidosis; Amylose AA; Aortite; Aortitis; Artérite à cellules géantes; Giant cell arteritis; Maladie de Horton; Temporal arteritis