title: Rotavirus Serum IgA Immune Response in Children Receiving Rotarix Coadministered With bOPV or IPV.
abstract: Vaccine schedules including bivalent oral and inactivated poliovirus vaccines will replace trivalent oral poliovirus vaccines in 2016.
  
  
  
  We evaluated rotavirus immunoglobulin A seroresponses when the second dose of Rotarix at 16 weeks was given concomitantly with inactivated or bivalent oral poliovirus vaccines.
  
  
  
  Rotavirus immunoglobulin A seroresponse rate at week 28 was 15% lower in recipients of bivalent oral poliovirus vaccines compared with inactivated poliovirus vaccines.
  
  
  
  Bivalent oral poliovirus vaccine decreases rotavirus IgA seroresponse rates when coadministered at 16 weeks of age.
authors.affiliation: From the *Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas; †Faculty of Medicine, Microbiology and Mycology Program, Institute of Biomedical Sciences; ‡Faculty of Medicine, Department of Pediatrics, Exequiel González Cortes Hospital, Universidad de Chile, Santiago, Chile; §Bill & Melinda Gates Foundation, Seattle, WA; ¶Fred Hutchinson Cancer Research Center, Seattle, Washington; and ‖Global Research in Infectious Diseases, Rio de Janeiro, Brazil.
authors.forename: Sasirekha
authors.initials: S
authors.lastname: Ramani
authors.forename: Nora
authors.initials: N
authors.lastname: Mamani
authors.forename: Rodolfo
authors.initials: R
authors.lastname: Villena
authors.forename: Ananda S
authors.initials: AS
authors.lastname: Bandyopadhyay
authors.forename: Chris
authors.initials: C
authors.lastname: Gast
authors.forename: Alicia
authors.initials: A
authors.lastname: Sato
authors.forename: Daniel
authors.initials: D
authors.lastname: Laucirica
authors.forename: Ralf
authors.initials: R
authors.lastname: Clemens
authors.forename: Mary K
authors.initials: MK
authors.lastname: Estes
authors.forename: Miguel L
authors.initials: ML
authors.lastname: O'Ryan
mesh_terms: D000914:Antibodies, Viral / Q000097:blood*; D006801:Humans; D007070:Immunoglobulin A / Q000097:blood*; D007223:Infant; D023321:Poliovirus Vaccines / Q000276:immunology*; D012401:Rotavirus / Q000276:immunology; D012400:Rotavirus Infections / Q000453:epidemiology / Q000276:immunology* / Q000517:prevention & control*; D022243:Rotavirus Vaccines / Q000276:immunology*; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; D007070:Immunoglobulin A; D023321:Poliovirus Vaccines; D022243:Rotavirus Vaccines