title: Molecular Determinants of Milk Lactoferrin as a Bioactive Compound in Early Neurodevelopment and Cognition.
abstract: Lactoferrin is a sialic acid-rich, iron-binding milk glycoprotein, known to have multifunctional health benefits, including its ability to modulate immune function and facilitate iron absorption, as well as its antibacterial and antiinflammatory actions. Human milk contains significantly higher lactoferrin levels than bovine milk at the same stages of lactation. The purpose of this review is to discuss the current state of knowledge of lactoferrin as a conditional nutrient for neurodevelopment, neuroprotection, and cognitive function during the period of rapid brain growth.
authors.affiliation: Discipline of Physiology, School of Animal and Veterinary Sciences, Charles Sturt University, Wagga Wagga, Australia; School of Medicine, Xiamen University, Xiamen City, P.R. China. Electronic address: biwang@csu.edu.au.
authors.forename: Bing
authors.initials: B
authors.lastname: Wang
mesh_terms: D000818:Animals; D001921:Brain / Q000254:growth & development*; D002417:Cattle; D003071:Cognition / Q000502:physiology*; D006801:Humans; D007223:Infant; D007227:Infant Nutritional Physiological Phenomena; D007231:Infant, Newborn; D007781:Lactoferrin / Q000737:chemistry / Q000502:physiology*; D008892:Milk / Q000737:chemistry / Q000502:physiology*; D008895:Milk, Human / Q000737:chemistry / Q000502:physiology; D013552:Swine
chemical_list: C490098:LTF protein, human; D007781:Lactoferrin