title: miRNAFold: a web server for fast miRNA precursor prediction in genomes.
abstract: Computational methods are required for prediction of non-coding RNAs (ncRNAs), which are involved in many biological processes, especially at post-transcriptional level. Among these ncRNAs, miRNAs have been largely studied and biologists need efficient and fast tools for their identification. In particular, ab initio methods are usually required when predicting novel miRNAs. Here we present a web server dedicated for miRNA precursors identification at a large scale in genomes. It is based on an algorithm called miRNAFold that allows predicting miRNA hairpin structures quickly with high sensitivity. miRNAFold is implemented as a web server with an intuitive and user-friendly interface, as well as a standalone version. The web server is freely available at: http://EvryRNA.ibisc.univ-evry.fr/miRNAFold.
authors.affiliation: IBISC-IBGBI, Université Evry, Genopole, 23 Boulevard de France, 91037 Evry CEDEX, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Tav
authors.affiliation: IBISC-IBGBI, Université Evry, Genopole, 23 Boulevard de France, 91037 Evry CEDEX, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Tempel
authors.affiliation: IBISC-IBGBI, Université Evry, Genopole, 23 Boulevard de France, 91037 Evry CEDEX, France.
authors.forename: Laurent
authors.initials: L
authors.lastname: Poligny
authors.affiliation: IBISC-IBGBI, Université Evry, Genopole, 23 Boulevard de France, 91037 Evry CEDEX, France Institute of Plant Sciences Paris Saclay (IPS2), CNRS, INRA, Université Paris-Sud, Université Evry, Université Paris-Saclay, Batiment 630, 91405 Orsay, France fariza.tahi@ibisc.univ-evry.fr.
authors.forename: Fariza
authors.initials: F
authors.lastname: Tahi
mesh_terms: D000465:Algorithms; D000818:Animals; D003196:Computer Graphics; D016678:Genome; D006801:Humans; D016247:Information Storage and Retrieval; D020407:Internet; D035683:MicroRNAs / Q000145:classification / Q000235:genetics*; D010944:Plants / Q000235:genetics; D059370:RNA Folding; D012322:RNA Precursors / Q000145:classification / Q000235:genetics*; D017423:Sequence Analysis, RNA; D012984:Software
chemical_list: D035683:MicroRNAs; D012322:RNA Precursors