title: Pharmacologic Therapy of Type 2 Diabetes.
abstract: Type 2 diabetes (T2DM) is a common condition. Treatment of diabetes and related complications can be complex. In addition to lifestyle changes, medications play an important role in controlling patients' blood glucose levels and preventing complications. From an individual and societal standpoint, it is also an expensive disease. Medical spending attributed to diabetes per individual is significant. With appropriate therapy, patients can lead full, healthy lives with the disease, so making informed decisions regarding pharmacotherapy for T2DM is clearly of great importance.
authors.affiliation: Department of Medicine, Division of General Internal Medicine, University of Washington, 4245 Roosevelt Way Northeast, Seattle, WA 98105, USA. Electronic address: sonic@uw.edu.
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Wright
authors.affiliation: Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, Endocrine and Diabetes Care Center, University of Washington, 4245 Roosevelt Way Northeast, Seattle, WA 98105, USA.
authors.forename: Tracy S
authors.initials: TS
authors.lastname: Tylee
mesh_terms: D000375:Aging; D001786:Blood Glucose; D001835:Body Weight; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000188:drug therapy*; D054873:Dipeptidyl-Peptidase IV Inhibitors / Q000627:therapeutic use; D004333:Drug Administration Routes; D052216:Glucagon-Like Peptide 1 / Q000819:agonists; D006442:Glycated Hemoglobin; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000191:economics / Q000627:therapeutic use*; D007328:Insulin / Q000627:therapeutic use; D008687:Metformin / Q000627:therapeutic use; D051437:Renal Insufficiency / Q000453:epidemiology; D000077203:Sodium-Glucose Transporter 2 Inhibitors; D013453:Sulfonylurea Compounds / Q000627:therapeutic use; D045162:Thiazolidinediones / Q000627:therapeutic use
chemical_list: D001786:Blood Glucose; D054873:Dipeptidyl-Peptidase IV Inhibitors; D052216:Glucagon-Like Peptide 1; D006442:Glycated Hemoglobin; D007004:Hypoglycemic Agents; D007328:Insulin; D008687:Metformin; D000077203:Sodium-Glucose Transporter 2 Inhibitors; D013453:Sulfonylurea Compounds; D045162:Thiazolidinediones
keywords: DPP-4 inhibitor; GLP-1 analog; Insulin; Metformin; SGLT-2 inhibitor; Sulfonylurea; Type 2 diabetes