title: Feature selection of fMRI data based on normalized mutual information and fisher discriminant ratio.
abstract: Pattern classification has been increasingly used in functional magnetic resonance imaging (fMRI) data analysis. However, the classification performance is restricted by the high dimensional property and noises of the fMRI data. In this paper, a new feature selection method (named as "NMI-F") was proposed by sequentially combining the normalized mutual information (NMI) and fisher discriminant ratio. In NMI-F, the normalized mutual information was firstly used to evaluate the relationships between features, and fisher discriminant ratio was then applied to calculate the importance of each feature involved. Two fMRI datasets (task-related and resting state) were used to test the proposed method. It was found that classification base on the NMI-F method could differentiate the brain cognitive and disease states effectively, and the proposed NMI-F method was prior to the other related methods. The current results also have implications to the future studies.
authors.affiliation: Beijing Municipal Key Laboratory of Multimedia and Intelligent Software Technology, College of Computer Science and Technology, Beijing University of Technology, Beijing, China.
authors.forename: Yanbin
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Beijing Municipal Key Laboratory of Multimedia and Intelligent Software Technology, College of Computer Science and Technology, Beijing University of Technology, Beijing, China.
authors.forename: Junzhong
authors.initials: J
authors.lastname: Ji
authors.affiliation: Department of Radiology, Xuanwu Hospital, Capital Medical University, Beijing, China.|Beijing Key Laboratory of Magnetic Resonance Imaging and Brain Informatics, Beijing, China.
authors.forename: Peipeng
authors.initials: P
authors.lastname: Liang
mesh_terms: D000465:Algorithms; D016208:Databases, Factual; D016002:Discriminant Analysis; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D000069550:Machine Learning; D008279:Magnetic Resonance Imaging / Q000379:methods*; D010363:Pattern Recognition, Automated
keywords: Pattern classification; feature selection; fisher discriminant ratio; functional magnetic resonance imaging (fMRI); normalized mutual information (NMI)