title: Primary cilia mechanosensing triggers autophagy-regulated cell volume control.
abstract: The primary cilium and the process of autophagy are thought to be in a functionally reciprocal relationship. In further support of this link, fluid flow sensing by the primary cilium is now shown to induce autophagy, which in turn regulates the volume of kidney epithelial cells.
authors.affiliation: Interfaculty Institute of Cell Biology, Eberhard Karls University Tübingen, and the International Max Planck Research School 'From Molecules to Organisms', Tübingen, Germany.
authors.forename: Zsuzsanna
authors.initials: Z
authors.lastname: Takacs
authors.affiliation: Interfaculty Institute of Cell Biology, Eberhard Karls University Tübingen, and the International Max Planck Research School 'From Molecules to Organisms', Tübingen, Germany.
authors.forename: Tassula
authors.initials: T
authors.lastname: Proikas-Cezanne
mesh_terms: D001343:Autophagy; D048429:Cell Size; D002923:Cilia / Q000378:metabolism*; D006801:Humans; D040542:Mechanotransduction, Cellular; D015398:Signal Transduction; D058570:TOR Serine-Threonine Kinases / Q000378:metabolism
chemical_list: D058570:TOR Serine-Threonine Kinases