title: Redox-Divergent Hydrogen-Retentive or Hydrogen-Releasing Synthesis of 3,4-Dihydroisoquinolines or Isoquinolines.
abstract: A rare Ru-catalyzed highly selective synthesis of 3,4-dihydroisoquinolines or isoquinolines is accomplished via a redox-divergent hydrogen-retentive or hydrogen-releasing fashion. Notably, high cis-selectivity of 3,4-dihydroisoquinolines is achieved. Potential applications are shown by gram-scale reactions and very concise synthesis of N-containing polycyclic aromatic compounds. Primary mechanistic investigations indicate that the sequence of the major pathway involves Ru-catalyzed C-H activation, alkyne insertion, and subsequent 6π-electrocyclization.
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.
authors.forename: Ke-Han
authors.initials: KH
authors.lastname: He
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Zhang
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.
authors.forename: Ming-Yu
authors.initials: MY
authors.lastname: Yang
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.|College of Chemistry and Chemical Engineering, Xi'an University of Science and Technology , Xi'an, Shaanxi 710054, China.
authors.forename: Kai-Li
authors.initials: KL
authors.lastname: Tang
authors.affiliation: College of Chemistry and Chemical Engineering, Xi'an University of Science and Technology , Xi'an, Shaanxi 710054, China.
authors.forename: Mengnan
authors.initials: M
authors.lastname: Qu
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.
authors.forename: You-Song
authors.initials: YS
authors.lastname: Ding
authors.affiliation: Center for Organic Chemistry, Frontier Institute of Science and Technology, Xi'an Jiaotong University , Xi'an, Shaanxi 710054, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li