title: Fine Needle Aspiration Cytology vs. the Postoperative Histology - the Continuing Need for Multi-Disciplinary Approach?
abstract: We set out to investigate the concordance rates that were observed between fine needle aspiration cytology (FNA) compared with that of the post operative histology obtained for thyroid nodules over an 8 year period at a large university hospital.A retrospective analysis of 355 cases was conducted; patients operated for hyperthyroidism were excluded for the purposes of this study. We identified malignancy in a total of 101 cases (28%) The chance of malignancy with 2 Thy1 specimens was 5% in this study and 9% was observed in those with a Thy 2 FNA. On the converse, 7% of patient had malignant cytology on FNA though post-operative histology turned out to be benign.This therefore highlights the potential for discordance between thyroid FNA cytology and post-operative histology in the assessment of any thyroid nodule and thus reinforcing the need for a multidisciplinary approach in the assessment of all thyroid nodules.
authors.affiliation: Diabetes & Endocrinology, NHS, Stoke On Trent, United Kingdom of Great Britain and Northern Ireland.
authors.forename: G
authors.initials: G
authors.lastname: Gill
authors.affiliation: Stoke On Trent, NHS, United Kingdom of Great Britain and Northern Ireland.
authors.forename: K
authors.initials: K
authors.lastname: Kalyanasundaram
authors.affiliation: Diabetes & Endocrinology, UHNM, Stoke On Trent, Great Britain and Northern Ireland.
authors.forename: G
authors.initials: G
authors.lastname: Varughese
authors.affiliation: Diabetes & Endocrinology, UHNM, Stoke On Trent, Great Britain and Northern Ireland.
authors.forename: P
authors.initials: P
authors.lastname: Wilson
authors.affiliation: Diabetes & Endocrinology, UHNM, Stoke On Trent, Great Britain and Northern Ireland.
authors.forename: L
authors.initials: L
authors.lastname: Varadhan
mesh_terms: D044963:Biopsy, Fine-Needle / Q000592:standards*; D006652:Histological Techniques / Q000592:standards*; D006801:Humans; D016606:Thyroid Nodule / Q000175:diagnosis* / Q000473:pathology; D013965:Thyroidectomy