title: Thigh muscle size and vascular function after blood flow-restricted elastic band training in older women.
abstract: We examined the effect of elastic band training with blood flow restriction (BFR) on thigh muscle size and vascular function in older women. Older women were divided into three groups: low-intensity elastic band BFR training (BFR-Tr, n = 10), middle- to high-intensity elastic band training (MH-Tr, n = 10), and no training (Ctrl, n = 10) groups. BFR-Tr and MH-Tr groups performed squat and knee extension exercises using elastic band, 2 days/week for 12 weeks. During BFR-Tr exercise session, subjects wore pressure cuffs around the most proximal region of both thighs. The following measurements were taken before (pre) and 3-5 days after (post) the final training session: MRI-measured muscle cross-sectional area (CSA) at mid-thigh, maximum voluntary isometric contraction (MVIC) of knee extension, central systolic blood pressure (c-SBP), central-augmentation index (c-AIx), cardio-ankle vascular index testing (CAVI), ankle-brachial pressure index (ABI). Quadriceps muscle CSA (6.9%) and knee extension MVIC (13.7%) were increased (p < 0.05) in the BFR-Tr group, but not in the MH-Tr and the Ctrl groups. Regarding c-SBP, c-AIx, CAVI and ABI, there were no changes between pre- and post- results among the three groups. Elastic band BFR training increases thigh muscle CSA as well as maximal muscle strength, but does not decrease vascular function in older women.
authors.affiliation: Graduate School of Medicine, University of Tokyo, Tokyo, Japan.|School of Nursing, Seirei Christopher University, Shizuoka, Japan.|Faculty of Medicine, Toho University, Chiba, Japan.
authors.forename: Tomohiro
authors.initials: T
authors.lastname: Yasuda
authors.affiliation: Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
authors.forename: Kazuya
authors.initials: K
authors.lastname: Fukumura
authors.affiliation: Faculty of Medicine, Toho University, Chiba, Japan.
authors.forename: Takanobu
authors.initials: T
authors.lastname: Tomaru
authors.affiliation: Graduate School of Medicine, University of Tokyo, Tokyo, Japan.|Heart Center, Dokkyo Medical University Hospital, Tochigi, Japan.
authors.forename: Toshiaki
authors.initials: T
authors.lastname: Nakajima
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D008875:Middle Aged; D053580:Muscle Strength; D018482:Muscle, Skeletal / Q000502:physiology; D012039:Regional Blood Flow; D055070:Resistance Training / Q000379:methods*; D055948:Sarcopenia / Q000517:prevention & control*; D013848:Thigh / Q000098:blood supply
keywords: Gerotarget; arterial stiffness; muscle hypertrophy; resistance exercise; sarcopenia; vascular occlusion