title: [Skin and soft tissue infections (SSTIs)].
abstract: Skin and Soft Tissue Infections (SSTIs) encompass a wide spectrum of inflammatory diseases of the skin, subcutis, fascia and muscles. Recent national trends indicate increasing rates of patients treated for these diagnoses at outpatient surgical department, but also of patients hospitalized with severe forms of SSTIs. Up to 90% fatality rates are reported in the literature for the most severe forms, resulting from underestimation of initial symptoms and therefore delayed onset of radical therapy only the phase of septic shock. The paper provides an interdisciplinary review of essential principles of the diagnosis and therapy of SSTIs, reflecting present knowledge supported by evidence-based medicine.
  
  
  BACKGROUND
  skin and soft tissue infections - SSTIs - necrotizing fasciitis - diagnosis - therapy.
authors.forename: R
authors.initials: R
authors.lastname: Gürlich
authors.forename: V
authors.initials: V
authors.lastname: Adámková
authors.forename: J
authors.initials: J
authors.lastname: Ulrych
authors.forename: H
authors.initials: H
authors.lastname: Brodská
authors.forename: V
authors.initials: V
authors.lastname: Janík
authors.forename: J
authors.initials: J
authors.lastname: Lindner
authors.forename: E
authors.initials: E
authors.lastname: Havel
mesh_terms: D018450:Disease Progression; D042241:Early Diagnosis; D061345:Early Medical Intervention; D019317:Evidence-Based Medicine; D006801:Humans; D012772:Shock, Septic / Q000209:etiology; D012874:Skin Diseases, Infectious / Q000150:complications / Q000175:diagnosis / Q000628:therapy*; D018461:Soft Tissue Infections / Q000150:complications / Q000175:diagnosis / Q000628:therapy*