title: Demographic and clinical characteristics and risk factors for Staphylococcal scalded skin syndrome in Hunan.
abstract: OBJECTIVE
  To realize the risk factors, clinical features, and treatments of Staphylococcal scalded skin syndrome (SSSS).
  
  
  METHODS
  The clinical features, laboratory findings, and treatment were retrospectively analyzed in 290 patients from Hunan Children's Hospital.
  
  
  RESULTS
  Of the 290 patients, less than 3 years old children were 76.6%. One hundred and nine patients had induced factors, and 177 patients had elevated white blood cell count. There were 168 patients with SSSS accompanied with fever, 34 patients accompanied with diarrhea, and 58 patients associated with septicemia. Eighty-five patients performed the bacterial cultures of the skin secretions, 21 did the throat swab, and 13 did both of the skin secretions and throat swab. Bacterial culture results showed that 119 samples were positive for Staphylococci. All patients were cured after antimicrobial therapy. The skin lesions were improved in 3.26 d. The mean hospital stay was 6.55 d. Recovery time of the body temperature was 3.48 d in average.
  
  
  CONCLUSIONS
  SSSS predominates in infants and children under 3 years old, and has tendency to combine with multi-organ symptoms. The early diagnosis and active antimicrobial treatment are the keys of successful treatments.
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Su
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Ji
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Emergency, Children's Hospital of Hunan Province, Changsha 410007, China.
authors.forename: Haiyan
authors.initials: H
authors.lastname: Luo
authors.affiliation: Department of Emergency, Children's Hospital of Hunan Province, Changsha 410007, China.
authors.forename: Zhenghui
authors.initials: Z
authors.lastname: Xiao
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Binping
authors.initials: B
authors.lastname: Luo
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Chen
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Panpan
authors.initials: P
authors.lastname: Liu
authors.affiliation: Department of Dermatology, Xiangya Hospital, Central South University, Changsha 410008; Hunan Key Laboratory of Skin Cancer and Psoriasis, Xiangya Hospital, Central South University, Changsha 410008, China.
authors.forename: Wu
authors.initials: W
authors.lastname: Zhu
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002675:Child, Preschool; D002681:China; D006801:Humans; D007223:Infant; D007902:Length of Stay; D012189:Retrospective Studies; D012307:Risk Factors; D018805:Sepsis; D012867:Skin / Q000382:microbiology; D013206:Staphylococcal Scalded Skin Syndrome / Q000175:diagnosis* / Q000188:drug therapy / Q000473:pathology*
chemical_list: D000900:Anti-Bacterial Agents