title: The effect of asymptomatic histological prostatitis on sexual function and lower urinary tract symptoms.
abstract: OBJECTIVE
  Prostatitis affects 10-14% of men of all ages and ethnicities. More than 50% of the men experience episodes of prostatitis at one time of their lives. Patients with CP typically have longlasting genitourinary/pelvic pain and obstructive and/or irritative voiding symptoms. Sexual dysfunction and psychological symptoms are frequently added to these symptoms. We also investigated the relationship between sexual functions, and lower urinary system symptoms, and asymptomatic histological prostatitis detected on transrectal ultrasound-guided (TRUS) biopsy performed with the indication of high PSA levels.
  
  
  METHODS
  Sixty cases compliant with the study criteria among patients who underwent prostate biopsies between September 2014 and June 2015 with the indication of higher PSA levels were included in the study. All patients were requested to complete IIEF-5 and IPSS forms one day previously. Based on histological analysis of biopsy materials, the patients were allocated into groups of BPH (simple BPH without histological prostatitis) (n:30) and histological chronic prostatitis (combination of BPH and histological prostatitis) (n:30).
  
  
  RESULTS
  Mean age of the cases was 65.73±5.01 (range, 56-75 yrs) years. PSA levels ranged between 4-15 ng/ml. A statistically significant intergroup difference was not found regarding mean age, BMIs, PSA levels, incidence rates of hypertension and coronary artery disease (p>0.05). Prostate volumes of the HCP group were higher than those of the BPH group , with statistically significant differences (p:0.001; p<0.01). Questionnaire forms of the patients included in the study were statistically evaluated, and mean IPSS score of the HCP group was found to be higher when compared with that of the BPH group, with statistically significant differences. (p:0.016; p<0.05). However mean IIEF score of the BPH group was higher than that of the HCP group, with statistically significant differences (p:0.039; p<0.05).
  
  
  CONCLUSIONS
  These findings suggested the presence of a correlation between chronic inflammation and lower urinary tract symptoms (LUTS). In addition, statistically significant lower IIEF values in patients with histological chronic prostatitis relative to those without suggested negative effects of even asymptomatic inflammation on sexual functions and mechanism of erection.
authors.affiliation: Haydarpasa Numune Research and Training Hospital. Istanbul. Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Urkmez
authors.affiliation: Department of Urology. Fatih Sultan Mehmet Research & Training Hospital. Istanbul. Turkey.
authors.forename: Ozgur Haki
authors.initials: OH
authors.lastname: Yuksel
authors.affiliation: Department of Urology. Fatih Sultan Mehmet Research & Training Hospital. Istanbul. Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Uruc
authors.affiliation: Department of Urology. Fatih Sultan Mehmet Research & Training Hospital. Istanbul. Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Akan
authors.affiliation: Department of Urology. Fatih Sultan Mehmet Research & Training Hospital. Istanbul. Turkey.
authors.forename: Caglar
authors.initials: C
authors.lastname: Yildirim
authors.affiliation: Department of Urology. Fatih Sultan Mehmet Research & Training Hospital. Istanbul. Turkey.
authors.forename: Aytac
authors.initials: A
authors.lastname: Sahin
authors.affiliation: Department of Urology. Fatih Sultan Mehmet Research & Training Hospital. Istanbul. Turkey.
authors.forename: Ayhan
authors.initials: A
authors.lastname: Verit
mesh_terms: D000368:Aged; D058070:Asymptomatic Diseases; D002908:Chronic Disease; D007172:Erectile Dysfunction / Q000209:etiology*; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology*; D008297:Male; D008875:Middle Aged; D011472:Prostatitis / Q000150:complications* / Q000473:pathology