title: A TRiP to the plasma membrane.
abstract: TRP ion channels are ubiquitously present in the mammalian body and take part in numerous key physiological functions, including temperature sensing, taste perception, osmo-regulation, cardiac function, renal function, development, and glucose homeostasis. The mechanisms whereby TRP channels are transported to the plasma membrane, where most of them exert their physiological actions, remains a poorly understood aspect of TRP channel biology.
authors.affiliation: Laboratory of Ion Channel Research and TRP channel Research Platform Leuven (TRPLe) Department of Cellular and Molecular Medicine ; KU Leuven; Belgium.
authors.forename: Debapriya
authors.initials: D
authors.lastname: Ghosh
authors.affiliation: Laboratory of Ion Channel Research and TRP channel Research Platform Leuven (TRPLe) Department of Cellular and Molecular Medicine ; KU Leuven; Belgium.
authors.forename: Thomas
authors.initials: T
authors.lastname: Voets
keywords: TRP channels; Total Internal Reflection Fluorescence Microscopy, (TIRFM); Total Internal Reflection – Fluorescence Recovery after Photobleaching, (TIR-FRAP); Transient receptor potential, (TRP); green fluorescent protein, (GFP); membrane trafficking; root-mean-square, (rms); square root of time following fusion, (√t); total internal reflection fluorescence microscopy; vesicle fusion