title: Propionibacterium acnes biofilm - A sanctuary for Staphylococcus aureus?
abstract: The purpose of this study was to measure the effect of combined culture of Propionibacterium acnes and Staphylococcus aureus on biofilm formation under different oxygen concentrations. We measured planktonic growth and biofilm formation of P. acnes and S. aureus alone and together under aerobic and anaerobic conditions. Both P. acnes and S. aureus grew under anaerobic conditions. When grown under anaerobic conditions, P. acnes with or without S. aureus formed a denser biomass biofilm than did S. aureus alone. Viable S. aureus was recovered from a16-day old combined P. acnes and S. aureus biofilm, but not a monomicrobial S. aureus biofilm.
authors.affiliation: Division of Infectious Diseases, Department of Medicine, USA.
authors.forename: Harmony
authors.initials: H
authors.lastname: Tyner
authors.affiliation: Division of Infectious Diseases, Department of Medicine, USA; Division Clinical Microbiology, Department of Laboratory Medicine and Pathology, USA. Electronic address: patel.robin@mayo.edu.
authors.forename: Robin
authors.initials: R
authors.lastname: Patel
mesh_terms: D000332:Aerobiosis; D000693:Anaerobiosis; D018441:Biofilms / Q000187:drug effects* / Q000254:growth & development; D018920:Coculture Techniques; D050296:Microbial Viability / Q000187:drug effects; D010100:Oxygen / Q000494:pharmacology*; D010933:Plankton / Q000187:drug effects* / Q000254:growth & development; D011425:Propionibacterium acnes / Q000187:drug effects* / Q000502:physiology; D013211:Staphylococcus aureus / Q000187:drug effects* / Q000502:physiology
chemical_list: D010100:Oxygen
keywords: Anaerobic; Biofilm; Propionibacterium acnes; Prosthetic joint infection; Staphylococcus aureus