title: Does basal luteinizing hormone help predict the fate of in vitro fertilization?
abstract: OBJECTIVE
  Evaluate the role of baseline serum luteinizing hormone (LH) in predicting the success of in-vitro fertilization (IVF) in terms of clinical pregnancy and live birth rate.
  
  
  METHODS
  Women who underwent IVF and/or intracytoplasmic sperm injection (ICSI), following either the agonist or the antagonist protocol, were retrospectively evaluated over a period of two years at the All India Institute of Medical Sciences, New Delhi. We investigated the correlation of serum LH levels in the follicular phase with pregnancy outcomes. A P-value lower than 0.05 was considered as statistically significant.
  
  
  RESULTS
  The individuals (351) were divided into four groups based on LH and FSH baseline values, and the levels were correlated with clinical pregnancy and live births. The highest clinical pregnancy rate (25%) was achieved in women with low LH (< 2IU/l); whereas the miscarriage rate was almost similar in all the groups. The pregnancy rate was the lowest (16%) in women with high LH levels (> 8IU/L). Pregnancy rates were intermediate (20%) if LH was intermediate (2-8IU/L). However, none of the results had statistical significance.
  
  
  CONCLUSIONS
  Early follicular serum LH levels before an IVF/ICSI treatment cycle did not have any clear relationship with clinical pregnancy or live birth rates.
authors.affiliation: Department of Obstetrics and Gynaecology, BPS Government College for Women, Khanpur Kalan, District Sonepat, Haryana, India.
authors.forename: Saloni
authors.initials: S
authors.lastname: Bansal
authors.affiliation: Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Neeta
authors.initials: N
authors.lastname: Singh
authors.affiliation: Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Prerna
authors.initials: P
authors.lastname: Gupta
authors.affiliation: Department of Obstetrics and Gynaecology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Neena
authors.initials: N
authors.lastname: Malhotra
authors.affiliation: Department of Obstetrics and Gynaecology, BPS Government College for Women, Khanpur Kalan, District Sonepat, Haryana, India.
authors.forename: Rajiv
authors.initials: R
authors.lastname: Mahendru
mesh_terms: D000328:Adult; D005260:Female; D005307:Fertilization in Vitro / Q000706:statistics & numerical data*; D006801:Humans; D007194:India; D050498:Live Birth / Q000453:epidemiology*; D007986:Luteinizing Hormone / Q000097:blood*; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D020554:Sperm Injections, Intracytoplasmic; D055815:Young Adult
chemical_list: D007986:Luteinizing Hormone
keywords: ICSI; IVF; clinical pregnancy rate; live birth rate; luteinizing hormone