title: Optic Nerve Assessment Using 7-Tesla Magnetic Resonance Imaging.
abstract: OBJECTIVE
  The purpose of this study was to correlate high-resolution magnetic resonance imaging (MRI) and histologic findings in a case of juxtapapillary choroidal melanoma with clinical evidence of optic nerve invasion.
  
  
  METHODS
  With institutional review board approval, an enucleated globe with choroidal melanoma and optic nerve invasion was imaged using a 7-tesla MRI followed by histopathologic evaluation.
  
  
  RESULTS
  Optical coherence tomography, B-scan ultrasonography, and 1.5-tesla MRI of the orbit (1-mm sections) could not detect optic disc invasion. Ex vivo, 7-tesla MRI detected optic nerve invasion, which correlated with histopathologic features.
  
  
  CONCLUSIONS
  Our case demonstrates the potential to document the existence of optic nerve invasion in the presence of an intraocular tumor, a feature that has a major bearing on decision making, particularly for consideration of enucleation.
authors.affiliation: Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Arun D
authors.initials: AD
authors.lastname: Singh
authors.affiliation: Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Sean M
authors.initials: SM
authors.lastname: Platt
authors.affiliation: Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Lisa
authors.initials: L
authors.lastname: Lystad
authors.affiliation: Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Lowe
authors.affiliation: Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Sehong
authors.initials: S
authors.lastname: Oh
authors.affiliation: Imaging Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Stephen E
authors.initials: SE
authors.lastname: Jones
authors.affiliation: Department of Ophthalmic Oncology, Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Yahya
authors.initials: Y
authors.lastname: Alzahrani
authors.affiliation: Pathology Institute, Cleveland Clinic, Cleveland, Ohio, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: Plesec
keywords: 7-tesla magnetic resonance imaging; Choroidal malignant melanoma; Optic nerve