title: Association of Exercise Capacity with Physical Functionality and Various Aspects of Fatigue in Patients with Coronary Artery Disease.
abstract: The aim of this study was to examine associations between exercise capacity-indexed as the metabolic equivalent of the task-and various aspects of subjective fatigue, physical functionality, and depression in patients with coronary artery disease. A cross-sectional design was used. Patients with stable coronary artery disease (N = 240) underwent an exercise stress test and completed self-report assessments of depression, subjective physical limitations, vital exhaustion, and the impact of fatigue on physical, social, and cognitive functions. Associations between exercise capacity and these self-report variables were assessed using bivariate correlations and a series of multivariate regressions. Exercise capacity was negatively associated with vital exhaustion, physical limitations, and impact of fatigue on physical and social functioning but not on cognitive functioning. There was a marginal association between exercise capacity and depression. The associations between exercise capacity and fatigue remained significant even after controlling for effects of age, body mass index, gender, education, and comorbid diabetes mellitus. The main conclusion of the study is that in patients with coronary artery disease, exercise capacity has the strongest predictability for physical fatigue, but, importantly, it also independently predicts the feeling of loss of energy and malaise.
authors.affiliation: a University of Pécs.
authors.forename: Alexandra
authors.initials: A
authors.lastname: Nagy
authors.affiliation: a University of Pécs.
authors.forename: Eszter
authors.initials: E
authors.lastname: Szabados
authors.affiliation: b State Hospital for Cardiology.
authors.forename: Attila
authors.initials: A
authors.lastname: Simon
authors.affiliation: a University of Pécs.
authors.forename: Béla
authors.initials: B
authors.lastname: Mezey
authors.affiliation: a University of Pécs.
authors.forename: Barbara
authors.initials: B
authors.lastname: Sándor
authors.affiliation: a University of Pécs.
authors.forename: István
authors.initials: I
authors.lastname: Tiringer
authors.affiliation: a University of Pécs.
authors.forename: Kálmán
authors.initials: K
authors.lastname: Tóth
authors.affiliation: c University of Szeged.
authors.forename: Krisztina
authors.initials: K
authors.lastname: Bencsik
authors.affiliation: a University of Pécs.
authors.forename: Árpád
authors.initials: Á
authors.lastname: Csathó
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D003324:Coronary Artery Disease / Q000150:complications / Q000523:psychology*; D003430:Cross-Sectional Studies; D003863:Depression / Q000150:complications / Q000523:psychology; D015444:Exercise / Q000523:psychology*; D005080:Exercise Test; D005221:Fatigue / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000076604:Physical Functional Performance
keywords: coronary artery disease; exercise capacity; fatigue; vital exhaustion