title: Epicardial fat tissue in patients with psoriasis:a systematic review and meta-analysis.
abstract: BACKGROUND
  Several studies have been performed to investigate the relationship between psoriasis and epicardial fat tissue (EFT). However, the number of patients of every single study is relatively small.
  
  
  OBJECTIVE
  We carried out a meta-analysis to evaluate whether EFT is associated with psoriasis.
  
  
  METHODS
  A search of PubMed, Ovid Embase, Ovid Medline, the Cochrane Library and Chinese BioMedical Literature Database (CBM) for controlled trials was done from inception to January 20th, 2016. Published trials that included a psoriasis group and a control group without psoriasis with data for at least epicardial fat tissue (EFT) were included. All statistical analyses were conducted using the Stata 12.0 (Stata Corporation, College Station, TX, USA).
  
  
  RESULTS
  There were 5 trials involving 731 patients. Patients with psoriasis showed significantly higher EFT than control group (SMD: 0.86, 95 % CI: 0.27-1.46, P = 0.004).
  
  
  CONCLUSIONS
  Patients with psoriasis have higher EFT compared to control subjects without psoriasis.
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, 610041, China.
authors.forename: Xiaoxue
authors.initials: X
authors.lastname: Wang
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, 610041, China. guozp0128@163.com.
authors.forename: Zaipei
authors.initials: Z
authors.lastname: Guo
authors.affiliation: Department of Liver Surgery, Liver Transplantation Division, West China Hospital, Sichuan University, Chengdu, 610041, China.
authors.forename: Zexin
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, 610041, China.
authors.forename: Yuting
authors.initials: Y
authors.lastname: Bao
authors.affiliation: Department of Dermatovenereology, West China Hospital, Sichuan University, Chengdu, 610041, China.
authors.forename: Beichen
authors.initials: B
authors.lastname: Yang
mesh_terms: D000273:Adipose Tissue / Q000000981:diagnostic imaging / Q000473:pathology*; D000328:Adult; D002318:Cardiovascular Diseases / Q000000981:diagnostic imaging / Q000209:etiology / Q000473:pathology*; D002986:Clinical Trials as Topic; D004452:Echocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010496:Pericardium / Q000000981:diagnostic imaging / Q000473:pathology*; D011565:Psoriasis / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology*; D012307:Risk Factors; D014057:Tomography, X-Ray Computed
keywords: Epicardial fat tissue; Meta-analysis; Psoriasis