title: Reduction of liver function delays resumption of postpartum ovarian activity and alters the synthesis of acute phase proteins in dairy cows.
abstract: The aim of this study was to evaluate the concentration of acute phase proteins, milk production, and resumption of postpartum ovarian activity of clinically healthy dairy cows in a semi-extensive system with different Liver Functionality Index (LFI) values. The animals were divided into two groups: Low LFI (LLFI: -7 to -12; n: 10) and High LFI (HLFI: -7 to -4; n: 10). Animals with LLFI had lower paraoxonase activity and lower albumin concentration in the pre- and postpartum periods (P<0.05), higher non-esterified fatty acids prepartum (P<0.005), and higher haptoglobin concentration postpartum (P<0.01). The LLFI group showed lower resumption of ovarian activity until 44days postpartum (29%; P<0.05) than HLFI (86%). Milk production did not differ between groups. Therefore, this study suggests that the LFI is an important biomarker of synthesis of acute phase proteins and the first ovulation interval, and it can be used to improve the production and reproductive performance.
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil. Electronic address: paulamontagner@gmail.com.
authors.forename: Paula
authors.initials: P
authors.lastname: Montagner
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Ana Rita Tavares
authors.initials: AR
authors.lastname: Krause
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Schwegler
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Marina Menoncin
authors.initials: MM
authors.lastname: Weschenfelder
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Viviane Rohrig
authors.initials: VR
authors.lastname: Rabassa
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Augusto
authors.initials: A
authors.lastname: Schneider
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Rubens Alves
authors.initials: RA
authors.lastname: Pereira
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Cássio Cassal
authors.initials: CC
authors.lastname: Brauner
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Francisco Augusto Burkert
authors.initials: FA
authors.lastname: Del Pino
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Fernanda Medeiros
authors.initials: FM
authors.lastname: Gonçalves
authors.affiliation: Federal University of Pelotas, Brazil, CEP 96010-900 Pelotas, RS, Brazil; Núcleo de Pesquisa, Ensino e Extensão em Pecuária - Livestock Research, Education and Extension Center (NUPEEC - http://www.ufpel.edu.br/nupeec), CEP 96010-900 Pelotas, RS, Brazil.
authors.forename: Marcio Nunes
authors.initials: MN
authors.lastname: Corrêa
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism*; D000818:Animals; D002417:Cattle / Q000097:blood* / Q000502:physiology; D005230:Fatty Acids, Nonesterified; D005260:Female; D007774:Lactation / Q000502:physiology*; D008099:Liver / Q000502:physiology*; D010060:Ovulation / Q000502:physiology*; D049590:Postpartum Period / Q000502:physiology*; D012098:Reproduction
chemical_list: D000209:Acute-Phase Proteins; D005230:Fatty Acids, Nonesterified
keywords: Albumin; Haptoglobin; Liver Functionality Index; Ovarian activity; Paraoxonase