title: [The effect of antihypertensive treatment on patients with diabetes depends on the values of blood pressure: a systematic survey and meta-analyses].
abstract: What was already known about these problems before the publication of the Northern Swedish study? Hypertension is the most important risk factor for mortality and cardiovascular disease on a global scale. Patients with diabetes mellitus demonstrate an increased risk for cardiovascular disease and they often also have hypertension at the same time. Antihypertensive treatment reduces the risk of cardiovascular diseases in patients with diabetes, however an optimum value of blood pressure is a matter of debate. What is the special contribution of the Swedish study? Antihypertensive treatment in patients with diabetes and a systolic pressure higher than 140 mm Hg brings with it a decreased risk of mortality and cardiovascular disease. Antihypertensive treatment in patients with dia-betes and a systolic lower than 140 mm Hg, however, brings with it an increased risk of mortality and cardiovascular disease. The interaction between systolic pressure values before the treatment and during it is significant.
authors.forename: Jiří
authors.initials: J
authors.lastname: Widimský
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure; D002318:Cardiovascular Diseases / Q000209:etiology / Q000517:prevention & control*; D048909:Diabetes Complications; D003971:Diastole; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000188:drug therapy*; D013599:Systole
chemical_list: D000959:Antihypertensive Agents