title: Symptomatic hypophosphataemic osteomalacia secondary to the treatment with iron carboxymaltose detected in bone scintigraphy.
abstract: The development of hypophosphataemic osteomalacia has been linked with several treatments, mainly antiretroviral and intravenous iron administration. The frequency of the hypophosphataemia requires monitoring the phosphate after the administration of iron carboxymaltose. We describe a case of a woman with no calcium-phosphorous metabolism disorder, to whom this treatment was prescribed for anaemia due to menorrhagia and intolerance to oral iron. She started with oligoarticular pain, which was spreading with a significant functional loss. The relationship with the administration of intravenous iron was discovered when scintigraphic findings together with laboratory results led to a diagnosis of hypophosphataemic osteomalacia. The patient responded satisfactorily to treatment with phosphate both clinically and in the follow-up bone scintigraphy.
authors.affiliation: Servicio de Medicina Nuclear, Hospital Universitario Miguel Servet , Zaragoza, España. Electronic address: msangros@comz.org.
authors.forename: M J
authors.initials: MJ
authors.lastname: Sangrós Sahún
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario de Navarra , Pamplona, España. Electronic address: elena.goni.girones@navarra.es.
authors.forename: E
authors.initials: E
authors.lastname: Goñi Gironés
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario de Navarra , Pamplona, España. Electronic address: alicia.camarero.salazar@cfnavarra.es.
authors.forename: A
authors.initials: A
authors.lastname: Camarero Salazar
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario de Navarra , Pamplona, España. Electronic address: cestebae@hotmail.com.
authors.forename: C
authors.initials: C
authors.lastname: Estébanez Estébanez
authors.affiliation: Servicio de Medicina Nuclear, Complejo Hospitalario de Navarra , Pamplona, España. Electronic address: mmartilo@cfn.es.
authors.forename: M E
authors.initials: ME
authors.lastname: Lozano Martínez
mesh_terms: D000328:Adult; D001842:Bone and Bones / Q000000981:diagnostic imaging*; D005260:Female; D005290:Ferric Compounds / Q000009:adverse effects*; D006801:Humans; D017674:Hypophosphatemia / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D008320:Maltose / Q000009:adverse effects / Q000031:analogs & derivatives*; D010018:Osteomalacia / Q000139:chemically induced* / Q000000981:diagnostic imaging*; D011877:Radionuclide Imaging
chemical_list: D005290:Ferric Compounds; C522335:ferric carboxymaltose; D008320:Maltose
keywords: Bone scintigraphy; Ferric carboxymaltose; Gammagrafía ósea; Hierro carboximaltosa; Hipofosfatemia; Hypophosphataemia; Osteomalacia