title: Antibiotic consumption in Turkish hospitals; a multi-centre point prevalence study.
abstract: This multi-centre study aimed to determine the antibiotic consumption in Turkish hospitals by point prevalence. Antibiotic consumption of 14 centres was determined using the DDD method. Among hospitalized patients, 44.8% were using antibiotics and the total antibiotic consumption was 674.5 DDD/1000 patient-days (DPD). 189.6 (28%) DPD of the antibiotic consumption was restricted while 484.9 (72%) DPD was unrestricted. Carbapenems (24%) and beta lactam/beta lactamase inhibitors (ampicillin-sulbactam or amoxicillin-clavulanate; 22%) were the most commonly used restricted and unrestricted antibiotics. Antibiotics were most commonly used in intensive care units (1307.7 DPD). Almost half of the hospitalized patients in our hospitals were using at least one antibiotic. Moreover, among these antibiotics, the most commonly used ones were carbapenems, quinolones and cephalosporins, which are known to cause collateral damage. We think that antibiotic resistance, which is seen at considerably high rates in our hospitals, is associated with this level of consumption.
authors.affiliation: a Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology , Sakarya University , Sakarya , Turkey.
authors.forename: Ertugrul
authors.initials: E
authors.lastname: Guclu
authors.affiliation: a Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology , Sakarya University , Sakarya , Turkey.
authors.forename: Aziz
authors.initials: A
authors.lastname: Ogutlu
authors.affiliation: a Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology , Sakarya University , Sakarya , Turkey.
authors.forename: Oguz
authors.initials: O
authors.lastname: Karabay
authors.affiliation: b Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology , Izmir Katip Celebi University , Izmir , Turkey.
authors.forename: Tuna
authors.initials: T
authors.lastname: Demirdal
authors.affiliation: c Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology , Necmettin Erbakan University , Konya , Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Erayman
authors.affiliation: d Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology , Dicle University , Diyarbakır , Turkey.
authors.forename: Salih
authors.initials: S
authors.lastname: Hosoglu
authors.affiliation: e Department of Infectious Diseases and Clinical Microbiology , GATA Haydarpasa Training and Research Hospital , Istanbul , Turkey.
authors.forename: Vedat
authors.initials: V
authors.lastname: Turhan
authors.affiliation: f Department of Infectious Diseases and Clinical Microbiology , Haydarpasa Numune Training and Research Hospital , Istanbul , Turkey.
authors.forename: Serpil
authors.initials: S
authors.lastname: Erol
authors.affiliation: g Department of Infectious Diseases and Clinical Microbiology , Antalya Training and Research Hospital , Antalya , Turkey.
authors.forename: Nefise
authors.initials: N
authors.lastname: Oztoprak
authors.affiliation: h Department of Infectious Diseases and Clinical Microbiology , Dr. Lutfi Kirdar Kartal Training and Research Hospital , Istanbul , Turkey.
authors.forename: Ayse
authors.initials: A
authors.lastname: Batirel
authors.affiliation: i Department of Infectious Diseases and Clinical Microbiology , Ankara Diskapi Yildirim Beyazit Education and Research Hospital , Ankara , Turkey.
authors.forename: Fatma Aybala
authors.initials: FA
authors.lastname: Altay
authors.affiliation: j Health Science Institute, Sakarya University , Sakarya , Turkey.
authors.forename: Gulsum
authors.initials: G
authors.lastname: Kaya
authors.affiliation: k Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Yuzuncuyıl University , Van , Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Karahocagil
authors.affiliation: l Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Mugla Sıtkı Kocman University , Mugla , Turkey.
authors.forename: Hamdi
authors.initials: H
authors.lastname: Sozen
authors.affiliation: m Department of Infectious Diseases and Clinical Microbiology , Umraniye Training and Research Hospital , Istanbul , Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Yildirim
authors.affiliation: n Division of Infectious Diseases and Clinical Microbiology , Health Ministry Basaksehir State Hospital , Istanbul , Turkey.
authors.forename: Funda
authors.initials: F
authors.lastname: Kocak
authors.affiliation: o Division of Infectious Diseases and Clinical Microbiology , Nisa Private Hospital , Istanbul , Turkey.
authors.forename: Bahri
authors.initials: B
authors.lastname: Teker
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D003430:Cross-Sectional Studies; D004363:Drug Utilization / Q000706:statistics & numerical data*; D006761:Hospitals / Q000706:statistics & numerical data; D006801:Humans; D015995:Prevalence; D014421:Turkey
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotic; Antibiotic stewardship; Consumption; Hospital