title: Effect of oligochitosan and oligo-β-glucan supplementation on growth, innate immunity, and disease resistance of striped catfish (Pangasianodon hypophthalmus).
abstract: Oligochitosan (COS) and oligo-β-glucan (βOG) were prepared by gamma Co-60 irradiation of chitosan/H2O2and β-glucan/H2O2solutions. The striped catfish (Pangasianodon hypophthalmus) was fed diets containing 0-200 mg COS, βOG, and a mixture of COS/βOG per kg feed for 45 days, and then challenged with Edwardsiella ictaluri bacterium. The effects of supplemented COS, βOG, and a mixture of COS/βOG on immune stimulation and growth performance in striped catfish were investigated. The results indicated that when striped catfish fed with 100-200 mg COS or βOG/kg feed the growth performance was significantly improved and the mortality was considerably decreased. Furthermore, striped catfish fed with supplementation of 50 mg COS + 50 mg βOG/kg feed was the best for increasing weight gain (∼26%) and for decreasing mortality (∼38%) compared with the control group. Moreover, phagocytic activity and lysozyme activity of fish were enhanced by feeding diet-supplemented COS and/or βOG. Thus, COS and/or βOG can be potentially utilized as the immunostimulants and growth promoters for aquaculture.
authors.affiliation: Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, Thu duc District, Ho Chi Minh City, Vietnam.
authors.forename: Ngoc Duy
authors.initials: ND
authors.lastname: Nguyen
authors.affiliation: Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, Thu duc District, Ho Chi Minh City, Vietnam.
authors.forename: Phu
authors.initials: P
authors.lastname: Van Dang
authors.affiliation: Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, Thu duc District, Ho Chi Minh City, Vietnam.
authors.forename: Anh Quoc
authors.initials: AQ
authors.lastname: Le
authors.affiliation: Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, Thu duc District, Ho Chi Minh City, Vietnam.
authors.forename: Thi Kim Lan
authors.initials: TKL
authors.lastname: Nguyen
authors.affiliation: Research Institute for Aquaculture No. 2, 3 Districts, Ho Chi Minh City, Vietnam.
authors.forename: Duy Hai
authors.initials: DH
authors.lastname: Pham
authors.affiliation: Research Institute for Aquaculture No. 2, 3 Districts, Ho Chi Minh City, Vietnam.
authors.forename: Nguyen
authors.initials: N
authors.lastname: Van Nguyen
authors.affiliation: Research and Development Center for Radiation Technology, Vietnam Atomic Energy Institute, Thu duc District, Ho Chi Minh City, Vietnam.
authors.forename: Quoc Hien
authors.initials: QH
authors.lastname: Nguyen
mesh_terms: D000818:Animals; D002397:Catfishes / Q000254:growth & development / Q000276:immunology; D002686:Chitin / Q000008:administration & dosage / Q000031:analogs & derivatives* / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan; D060467:Disease Resistance / Q000187:drug effects*; D005393:Fish Diseases / Q000188:drug therapy* / Q000276:immunology / Q000382:microbiology; D007113:Immunity, Innate / Q000187:drug effects*; D009844:Oligosaccharides; D047071:beta-Glucans / Q000008:administration & dosage / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D009844:Oligosaccharides; D047071:beta-Glucans; C493484:oligochitosan; D002686:Chitin; D048271:Chitosan
keywords: Catfish; Growth; Immunostimulant; Oligo-β-glucan; Oligochitosan