title: Two-Dimensional Sonographic Evaluation of Endometrial Polyps - Parameters That Are Reassuring.
abstract: OBJECTIVE
  To assess intra-endometrial lesions according to five two-dimensional sonographic parameters for predicting malignancy.
  
  
  METHODS
  This is a retrospective analysis of stored digital images from consecutive pathological reports of patients with benign endometrial polyps and stage 1 endometrial carcinoma. Five sonographic parameters were evaluated: heterogeneous or complex echogenicity of the lesion, presence of a 'bright edge sign,' regular endometrial-myometrial junction, the presence of a normal endometrium adjacent to the lesion, and detection of small intralesional cysts. The sensitivity, specificity, PPV, and NPV of these parameters were calculated, as well as combinations of pairs of parameters.
  
  
  RESULTS
  Seventy-nine patients were eligible for the current study, 26 with benign endometrial polyps and 53 with stage 1 endometrial carcinoma. The sonographic appearance of numerous small intralesional cysts (cystic formation) was highly related to benign polyp; the presence of a lesion with heterogeneous echogenicity had sensitivity and specificity for malignancy of 63.5 and 88.5%, respectively.
  
  
  CONCLUSIONS
  We have shown that asymptomatic endometrial lesions, which are homogenous, have bright edges, and small intralesional cysts are likely to be benign Determining these parameters during sonographic evaluation can assist in identifying patients who will benefit from a follow-up strategy instead of an unnecessary surgical intervention.
authors.affiliation: Unit of Gynecological Ultrasonography, Rappaport Faculty of Medicine, Technion, Haifa, Israel.
authors.forename: Yael
authors.initials: Y
authors.lastname: Goldberg
authors.forename: Ofer
authors.initials: O
authors.lastname: Lavie
authors.forename: Rachel
authors.initials: R
authors.lastname: Mandel
authors.forename: Yuval
authors.initials: Y
authors.lastname: Kaufman
authors.forename: Yakir
authors.initials: Y
authors.lastname: Segev
authors.forename: Ron
authors.initials: R
authors.lastname: Auslender
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D016889:Endometrial Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D011127:Polyps / Q000000981:diagnostic imaging* / Q000473:pathology; D012189:Retrospective Studies; D012680:Sensitivity and Specificity; D014463:Ultrasonography; D014591:Uterine Diseases / Q000000981:diagnostic imaging* / Q000473:pathology