Synergistic Effects of Six Chronic Disease Pairs on Decreased Physical Activity: The SMILE Cohort Study.
Little is known about whether and how two chronic diseases interact with each other in modifying the risk of physical inactivity. The aim of the present study is to identify chronic disease pairs that are associated with compliance or noncompliance with the Dutch PA guideline recommendation and to study whether specific chronic disease pairs indicate an extra effect on top of the effects of the diseases individually. Cross-sectional data from 3,386 participants of cohort study SMILE were used and logistic regression analysis was performed to study the joint effect of the two diseases of each chronic disease pair for compliance with the Dutch PA guideline. For six chronic disease pairs, patients suffering from both diseases belonging to these disease pairs in question show a higher probability of noncompliance to the Dutch PA guideline, compared to what one would expect based on the effects of each of the two diseases alone. These six chronic disease pairs were chronic respiratory disease and severe back problems; migraine and inflammatory joint disease; chronic respiratory disease and severe kidney disease; chronic respiratory disease and inflammatory joint disease; inflammatory joint disease and rheumatoid arthritis; and rheumatoid arthritis and osteoarthritis of the knees, hips, and hands.
Department of Epidemiology and CAPHRI School for Public Health and Primary Care, Functioning and Rehabilitation Programme, Maastricht University, 6229 ER Maastricht, Netherlands.
Sarah
S
Dörenkamp
Department of Epidemiology and CAPHRI School for Public Health and Primary Care, Functioning and Rehabilitation Programme, Maastricht University, 6229 ER Maastricht, Netherlands.
Ilse
I
Mesters
Department of Methodology and Statistics and CAPHRI School for Public Health and Primary Care, Maastricht University, 6229 ER Maastricht, Netherlands; Department of Medical Informatics, Erasmus University Rotterdam, 3015 CE Rotterdam, Netherlands.
Rein
R
Vos
Department of Methodology and Statistics and CAPHRI School for Public Health and Primary Care, Maastricht University, 6229 ER Maastricht, Netherlands.
Jan
J
Schepers
Department of Family Medicine and CAPHRI School for Public Health and Primary Care, Maastricht University, 6229 ER Maastricht, Netherlands; Department of General Practice, Catholic University Leuven, 3000 Leuven, Belgium.
Marjan
M
van den Akker
Department of Epidemiology and CAPHRI School for Public Health and Primary Care, Functioning and Rehabilitation Programme, Maastricht University, 6229 ER Maastricht, Netherlands; Department of Vascular Surgery, Catharina Hospital, 5623 EJ Eindhoven, Netherlands.
Joep
J
Teijink
Department of Epidemiology and CAPHRI School for Public Health and Primary Care, Functioning and Rehabilitation Programme, Maastricht University, 6229 ER Maastricht, Netherlands.
Rob
R
de Bie
D000368:Aged; D000369:Aged, 80 and over; D015984:Causality; D015331:Cohort Studies; D015897:Comorbidity; D015444:Exercise / Q000523:psychology*; D005081:Exercise Therapy / Q000523:psychology / Q000706:statistics & numerical data*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000071069:Multiple Chronic Conditions / Q000453:epidemiology* / Q000523:psychology / Q000534:rehabilitation*; D009426:Netherlands / Q000453:epidemiology; D010349:Patient Compliance / Q000523:psychology / Q000706:statistics & numerical data*; D015995:Prevalence; D012307:Risk Factors; D040242:Risk Reduction Behavior; D057185:Sedentary Behavior; D016896:Treatment Outcome