Neuroendocrine Cancer of Rectum Metastasizing to Ovary.
Neuroendocrine carcinomas (NECs) are rare malignancies that originate from the hormone-producing cells of the body's neuroendocrine system. Rectal high grade NEC (HG-NEC) constituting less than 1% of colorectal cancers can cause large ovarian metastasis that may be the initial presenting complaint. Ovarian Krukenberg tumor from a primary rectal HG-NEC is a very unusual and exceedingly uncommon differential diagnosis for secondary ovarian malignancy. This case report describes one such extremely rare case of a woman who had presented to the gynecology department with features suggestive of ovarian malignancy and was ultimately diagnosed to have Krukenberg tumor originating from neuroendocrine cancer of rectum. We felt this is a good opportunity to spread more light on neuroendocrine neoplasms that are very rare in gynecological practice.
Department of OBG, Kasturba Medical College, Manipal University, Manipal 576104, India.
Sapna Vinit
SV
Amin
IVF and Reproductive Biology Centre, Maulana Azad Medical College, New Delhi 110002, India.
Aswathy
A
Kumaran
Department of OBG, Kasturba Medical College, Manipal University, Manipal 576104, India.
Sunanda
S
Bharatnur
Department of OBG, Kasturba Medical College, Manipal University, Manipal 576104, India.
Akhila
A
Vasudeva
Department of Medical Oncology, Kasturba Medical College, Manipal University, Manipal 576104, India.
Kartik
K
Udupa
Department of Surgery, Kasturba Medical College, Manipal University, Manipal 576104, India.
Dinesh Bangalore
DB
Venkateshiah
Department of Pathology, Melaka Manipal Medical College, Manipal University, Manipal 576104, India.
Shaila T
ST
Bhat