Exon skipping and aberrant signal peptide cleavage produce novel fibrinogen with an Aα chain lacking the first 42 residues.
Prof. Stephen Brennan, Molecular Pathology Laboratory, Canterbury Health Laboratories, PO Box 151, Christchurch 8011, New Zealand, Tel.: +64 3 364 0549, Fax: +64 3 364 0545, E-mail: steve.brennan@otago.ac.nz.
Stephen O
SO
Brennan
Andrew D
AD
Laurie
Simon
S
McRae
D000347:Afibrinogenemia / Q000097:blood / Q000235:genetics; D000595:Amino Acid Sequence; D005091:Exons; D005260:Female; D005340:Fibrinogen / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D015241:Fibrinogens, Abnormal / Q000737:chemistry / Q000235:genetics* / Q000378:metabolism; D006801:Humans; D008875:Middle Aged; D009154:Mutation; D010446:Peptide Fragments / Q000737:chemistry / Q000235:genetics / Q000378:metabolism; D017354:Point Mutation; D055503:Protein Multimerization / Q000235:genetics; D011499:Protein Processing, Post-Translational; D021382:Protein Sorting Signals / Q000235:genetics; D022821:RNA Splice Sites; D017384:Sequence Deletion; D021241:Spectrometry, Mass, Electrospray Ionization
D015241:Fibrinogens, Abnormal; D010446:Peptide Fragments; D021382:Protein Sorting Signals; D022821:RNA Splice Sites; C464794:fibrinogen Aalpha; C040078:fibrinogen Adelaide; D005340:Fibrinogen