A Previously Healthy Premature Infant Treated With Thrombolytic Therapy for Life-threatening Pulmonary Artery Thrombosis.
Pulmonary artery thrombosis is rarely reported in preterm neonates. Although treatment of neonatal thrombosis remains controversial, thrombolytic agents must be considered when the thrombosis is life threatening. We herein present a case of a preterm newborn with pulmonary artery thrombosis accompanied by acute-onset respiratory failure and cyanotic congenital heart disease. The thrombosis was successfully treated using tissue plasminogen activator. In conclusion, the thrombolytic therapy should be considered in treatment of patients in whom the thrombosis completely occludes the pulmonary arteries.
Departments of *Neonatology †Pediatric Cardiology, Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey.
Dilek
D
Ulubas Isik
Istemi H
IH
Celik
Osman
O
Yilmaz
Ahmet Y
AY
Bas
Nihal
N
Demirel
D006331:Heart Diseases / Q000151:congenital; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D011651:Pulmonary Artery / Q000473:pathology*; D012131:Respiratory Insufficiency; D015912:Thrombolytic Therapy / Q000379:methods*; D013927:Thrombosis / Q000188:drug therapy*; D010959:Tissue Plasminogen Activator / Q000627:therapeutic use
D010959:Tissue Plasminogen Activator