Advances and challenges in cryo ptychography at the Advanced Photon Source.
Ptychography has emerged as a nondestructive tool to quantitatively study extended samples at a high spatial resolution. In this manuscript, we report on recent developments from our team. We have combined cryo ptychography and fluorescence microscopy to provide simultaneous views of ultrastructure and elemental composition, we have developed multi-GPU parallel computation to speed up ptychographic reconstructions, and we have implemented fly-scan ptychography to allow for faster data acquisition. We conclude with a discussion of future challenges in high-resolution 3D ptychography.
Applied Physics, Northwestern University, Evanston IL 60208, USA.
J
J
Deng
X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
D J
DJ
Vine
X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
S
S
Chen
Mathematics and Computing Science Division, Argonne National Laboratory, Argonne, IL 60439, USA.
Y S G
YS
Nashed
Department of Physics & Astronomy, Northwestern University, Evanston, IL 60208, USA.
Q
Q
Jin
Mathematics and Computing Science Division, Argonne National Laboratory, Argonne, IL 60439, USA.
T
T
Peterka
X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA.
S
S
Vogt
X-ray Science Division, Advanced Photon Source, Argonne National Laboratory, Argonne, IL 60439, USA; Department of Physics & Astronomy and Chemistry of Life Processes Institute, Northwestern University, Evanston, IL 60208, USA.
C
C
Jacobsen
3D ptychography; cryogenic sample; fly scan; parallel computation; ptychography