Ability to downregulate the level of cyclin-dependent kinase inhibitor p27Kip1after DNA damage is retained in chronic lymphocytic leukemia cells with functional ATM/p53 signaling pathway.
a Department of Biology, Faculty of Medicine and Dentistry , Palacky University , Olomouc , Czech Republic.
Leona
L
Raskova Kafkova
b Center of Molecular Medicine , CEITEC - Central European Institute of Technology, Masaryk University , Brno , Czech Republic.
Veronika
V
Navrkalova
c Department of Hemato-Oncology, Faculty of Medicine and Dentistry , Palacky University and University Hospital Olomouc , Czech Republic.
Marie
M
Jarosova
b Center of Molecular Medicine , CEITEC - Central European Institute of Technology, Masaryk University , Brno , Czech Republic.
Tomas
T
Loja
b Center of Molecular Medicine , CEITEC - Central European Institute of Technology, Masaryk University , Brno , Czech Republic.
Jana
J
Chovancova
a Department of Biology, Faculty of Medicine and Dentistry , Palacky University , Olomouc , Czech Republic.
Jana
J
Kucerova
d Department of Immunology, Faculty of Medicine and Dentistry , Palacky University , Olomouc , Czech Republic.
Eva
E
Kriegova
c Department of Hemato-Oncology, Faculty of Medicine and Dentistry , Palacky University and University Hospital Olomouc , Czech Republic.
Vit
V
Prochazka
e Department of Surgery , University of Alabama at Birmingham , Birmingham , AL , USA.
Zdenek
Z
Novak
a Department of Biology, Faculty of Medicine and Dentistry , Palacky University , Olomouc , Czech Republic.
Dana
D
Simkova
b Center of Molecular Medicine , CEITEC - Central European Institute of Technology, Masaryk University , Brno , Czech Republic.
Sarka
S
Pospisilova
a Department of Biology, Faculty of Medicine and Dentistry , Palacky University , Olomouc , Czech Republic.
Vladimir
V
Divoky
D000328:Adult; D000368:Aged; D064007:Ataxia Telangiectasia Mutated Proteins / Q000235:genetics / Q000378:metabolism*; D015153:Blotting, Western; D002453:Cell Cycle / Q000235:genetics; D050760:Cyclin-Dependent Kinase Inhibitor p27 / Q000235:genetics / Q000378:metabolism*; D004249:DNA Damage; D015536:Down-Regulation; D005434:Flow Cytometry; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000235:genetics / Q000378:metabolism*; D009154:Mutation; D015398:Signal Transduction / Q000235:genetics; D016159:Tumor Suppressor Protein p53 / Q000235:genetics / Q000378:metabolism*
D016159:Tumor Suppressor Protein p53; D050760:Cyclin-Dependent Kinase Inhibitor p27; D064007:Ataxia Telangiectasia Mutated Proteins