[Distribution characteristics of serotypes of invasive pneumococcal disease in Chinese mainland children].
OBJECTIVE
To systematically estimate the regional distributions of invasive pneumococcal disease (IPD)'s serotypes in children of Chinese mainland.


METHODS
The literatures which described at least 20 strains of streptococcus pneumonia samples isolated from children with IPD in Chinese mainland were included in this study. Finally, 39 literatures met the inclusion criteria and were reviewed in this study. The average frequency of each serotype of streptococcus pneumonia was calculated and the uncertainty of each serotype range was described by 95% CI.


RESULTS
This study analyzed a total of 7 391 strains of streptococcus pneumoniae samples which mainly came from north China, east China, central China, south China and southwest regions of China. The results showed that the most common streptococcus pneumonia serotype causing IPD was 19F[30.05% (28.16%-31.98%)], and the second serotype was 23F[12.16% (10.00%-14.28%)], and the others were 19A[9.19% (7.01%-11.37%)], 6B[7.30% (5.09%-9.50%)], 14[7.02% (4.82%-9.23%)], 6A[6.08% (3.87%-8.30%)]and 15B[6.53% (2.88%-7.34%)].


CONCLUSIONS
The most common streptococcus pneumoniae serotype is 19F, 23F, 19A, 6B, 14, 6A and 15B in Chinese Mainland.
Department of Respiratory Diseases, China-Japan Friendship Hospital, Beijing 100029, China.
N
N
Su
X
X
Han
Y M
YM
Yang
J T
JT
Lin
D002648:Child; D002681:China / Q000453:epidemiology; D006801:Humans; D011008:Pneumococcal Infections / Q000453:epidemiology* / Q000382:microbiology*; D065288:Serogroup; D012703:Serotyping; D013296:Streptococcus pneumoniae / Q000145:classification*