Tumor-to-tumor metastasis: an unusual case of breast cancer metastatic to a solitary fibrous tumor.
Solitary fibrous tumor (SFT) is a rare mesenchymal neoplasm that most commonly involves the visceral or parietal pleura, but that has also been described arising from virtually all organs. This neoplasm exhibits rich vascularity, a characteristic it shares with renal cell carcinoma, making these tumors especially suitable for harboring metastases. We present a case of a 64-year-old woman with history of right breast cancer treated six years previously and who presents with a left pulmonary SFT containing metastatic invasive ductal breast carcinoma as well as a synchronous contralateral primary adenocarcinoma of the lung. The literature on tumor-to-tumor metastasis is then reviewed.
1 Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 2 Department of Thoracic Oncology, 3 Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA ; 4 Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Frank O
FO
Velez-Cubian
1 Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 2 Department of Thoracic Oncology, 3 Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA ; 4 Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Robert C
RC
Gabordi
1 Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 2 Department of Thoracic Oncology, 3 Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA ; 4 Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Prudence V
PV
Smith
1 Department of Surgery, University of South Florida Morsani College of Medicine, Tampa, FL, USA ; 2 Department of Thoracic Oncology, 3 Department of Pathology, Moffitt Cancer Center, Tampa, FL, USA ; 4 Department of Oncologic Sciences, University of South Florida Morsani College of Medicine, Tampa, FL, USA.
Eric M
EM
Toloza
Breast cancer; lobectomy; lung cancer; metastasis; solitary fibrous tumor (SFT)