Tetrameric psuedo-peptide receptors with allosteric properties.
This paper reports the binding properties of tetrameric pseudo-peptide receptors for protonated cytidines. The receptors, which were isolated from a dynamic combinatorial chemistry (DCC) experiment, bind the analytes with affinities that depend on the presence or absence of excess acid, and with a stoichiometry that is both concentration and temperature dependent.
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. mlwaters@unc.edu mgagne@unc.edu.
Mee-Kyung
MK
Chung
U.S. Army Research Office, P. O. Box 12211, Research Triangle Park, NC 27709 USA.
Stephen J
SJ
Lee
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. mlwaters@unc.edu mgagne@unc.edu.
Marcey L
ML
Waters
Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. mlwaters@unc.edu mgagne@unc.edu.
Michel R
MR
Gagné