Decarboxylative Cascade Reactions of Dihydroxyfumaric Acid: A Preparative Approach to the Glyoxylate Scenario.
An operationally simple protocol is reported to generate an α-hydroxyacyl anion by the decarboxylation of dihydroxyfumaric acid. To date, the "missing" utilization of the hydroxyacyl anion in highly chemo- and stereoselective cascade reactions enables short and direct construction of carbohydrates.
Institute of Chemistry, Humboldt-University , Brook-Taylor Str. 2, 12489 Berlin, Germany.
Celin
C
Richter
Institute of Chemistry, Humboldt-University , Brook-Taylor Str. 2, 12489 Berlin, Germany.
Falko
F
Berndt
Institute of Chemistry, Humboldt-University , Brook-Taylor Str. 2, 12489 Berlin, Germany.
Tom
T
Kunde
Institute of Chemistry, Humboldt-University , Brook-Taylor Str. 2, 12489 Berlin, Germany.
Rainer
R
Mahrwald