Brain damage associated with apraxia of speech: evidence from case studies.
The site of crucial damage that causes acquired apraxia of speech (AOS) has been debated in the literature. This study presents five in-depth cases that offer insight into the role of brain areas involved in AOS. Four of the examined participants had a primary impairment of AOS either with (n = 2) or without concomitant mild aphasia (n = 2). The fifth participant presented with a lesion relatively isolated to the left anterior insula (AIns-L), damage that is rarely reported in the literature, but without AOS. Taken together, these cases challenge the role of the AIns-L and implicate the left motor regions in AOS.
a Department of Communication Sciences and Disorders , University of New Hampshire , Durham , NH , USA.
Dana
D
Moser
b Department of Communication Sciences and Disorders , University of South Carolina , Columbia , SC , USA.
Alexandra
A
Basilakos
b Department of Communication Sciences and Disorders , University of South Carolina , Columbia , SC , USA.
Paul
P
Fillmore
b Department of Communication Sciences and Disorders , University of South Carolina , Columbia , SC , USA.
Julius
J
Fridriksson
D000328:Adult; D000368:Aged; D001037:Aphasia / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001072:Apraxias / Q000000981:diagnostic imaging / Q000503:physiopathology*; D002540:Cerebral Cortex / Q000000981:diagnostic imaging / Q000473:pathology*; D004401:Dysarthria / Q000000981:diagnostic imaging / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged
Aphasia; apraxia of speech; insula; motor cortex; rolandic operculum