Twelve weeks supplementation with an extended-release caffeine and ATP-enhancing supplement may improve body composition without affecting hematology in resistance-trained men.
BACKGROUND
Increased ATP levels may enhance training-induced muscle accretion and fat loss, and caffeine is a known ergogenic aid. A novel supplement containing ancient peat and apple extracts has reported enhanced mitochondrial ATP production and it has been coupled with an extended-release caffeine. Therefore, the purpose of this investigation was to determine the effects of this supplement on body composition when used in conjunction with 12 weeks of resistance training.


METHODS
Twenty-one resistance-trained subjects (27.2 ± 5.6y; 173.5 ± 5.7 cm; 82.8 ± 12.0 kg) completed this study. Subjects supplemented daily with either 1 serving of the supplement (TRT), which consisted of 150 mg ancient peat and apple extracts, 180 mg blend of caffeine anhydrous and pterostilbene-bound caffeine, and 38 mg B vitamins, or an equal-volume, visually-identical placebo (PLA) 45 min prior to training or at the same time of day on rest days. Supervised resistance training consisted of 8 weeks of daily undulating periodized training followed by a 2-week overreach and a 2-week taper phase. Body composition was assessed using DEXA and ultrasound at weeks 0, 4, 8, 10, and 12. Vital signs and blood markers were assessed at weeks 0, 8, and 12.


RESULTS
Significant group x time (p < 0.05) interactions were present for cross-sectional area of the rectus femoris, which increased in TRT (+1.07 cm(2)) versus PLA (-0.08 cm(2)), as well as muscle thickness (TRT: +0.49 cm; PLA: +0.04 cm). A significant group x time (p < 0.05) interaction existed for creatinine (TRT: +0.00 mg/dL; PLA: +0.15 mg/dL) and estimated glomerular filtration rate (TRT: -0.70 mL/min/1.73; PLA: -14.6 mL/min/1.73), which remained within clinical ranges, but no other significant observations were observed.


CONCLUSIONS
Supplementation with a combination of extended-release caffeine and ancient peat and apple extracts may enhance resistance training-induced skeletal muscle hypertrophy without adversely affecting blood chemistry.
Department of Nutrition and Food Sciences, Texas Woman's University, 401 AME Drive #7101, Denton, TX 76207 USA.
Jordan M
JM
Joy
Department of Nutrition and Food Sciences, Texas Woman's University, 401 AME Drive #7101, Denton, TX 76207 USA.
Roxanne M
RM
Vogel
American Public University System, School of Health Sciences, Charles Town, WV USA.
Jordan R
JR
Moon
MusclePharm Sports Science Institute, MusclePharm Corp., Denver, CO USA.
Paul H
PH
Falcone
Maximum Mobile Fitness, Spearfish, SD USA.
Matt M
MM
Mosman
MusclePharm Sports Science Institute, MusclePharm Corp., Denver, CO USA.
Michael P
MP
Kim
D000255:Adenosine Triphosphate / Q000096:biosynthesis*; D000328:Adult; D015415:Biomarkers / Q000097:blood; D001772:Blood Cell Count; D001823:Body Composition / Q000187:drug effects*; D002110:Caffeine / Q000008:administration & dosage*; D003404:Creatinine / Q000097:blood; D019587:Dietary Supplements; D005919:Glomerular Filtration Rate; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D027845:Malus; D010919:Placebos; D010936:Plant Extracts / Q000008:administration & dosage; D052097:Quadriceps Muscle / Q000033:anatomy & histology; D055070:Resistance Training; D012987:Soil; D014803:Vitamin B Complex / Q000008:administration & dosage
D015415:Biomarkers; D008055:Lipids; D010919:Placebos; D010936:Plant Extracts; D012987:Soil; D014803:Vitamin B Complex; D002110:Caffeine; D000255:Adenosine Triphosphate; D003404:Creatinine
Elevatp; Ergogenic aid; Hypertrophy; Purenergy; Safety