[Confocal microscopy as an early relapse marker after keratoplasty due to Fusarium solani keratitis].
In the case of therapy-resistant keratitis an infection with Fusarium solani should be taken into consideration as a rare but very severe eye disease. In the majority of cases Fusarium solani keratitis will result in a protracted clinical course despite aggressive medicinal and surgical interventions. We describe the case of a referred patient after intensive topical, intracameral and systemic antibacterial and antimycotic therapy as well as surgical treatment with emergency keratoplasty à chaud because of Fusarium solani keratitis. The patient presented to our department with persistent discomfort for further therapeutic interventions. Using confocal microscopy we were able to demonstrate the presence of fungal hyphae in the host cornea and the graft, which was important for making further surgical decisions. Furthermore, this emphasizes the role of confocal microscopy as an early relapse marker during the clinical monitoring.
Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66424, Homburg/Saar, Deutschland. loay.daas@uks.eu.
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L
Daas
Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
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Bischoff-Jung
Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
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Viestenz
Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
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Seitz
Klinik für Augenheilkunde, Universitätsklinikum des Saarlandes UKS, Kirrberger Str. 100, Gebäude 22, 66424, Homburg/Saar, Deutschland.
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Viestenz
D015415:Biomarkers; D016039:Corneal Transplantation / Q000379:methods*; D003941:Diagnostic Techniques, Ophthalmological; D042241:Early Diagnosis; D005260:Female; D060585:Fusariosis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007634:Keratitis / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D018613:Microscopy, Confocal / Q000379:methods*; D008875:Middle Aged; D012008:Recurrence; D016896:Treatment Outcome
D015415:Biomarkers
Confocal microscopy; Fusarium solani; Hyperreflective lines; Mycotic keratitis; Relapse marker