Age-related oscillatory theta modulation of multisensory integration in frontocentral regions.
This study used electroencephalogram measurements to investigate the effects of aging on oscillatory theta modulation during an audiovisual discrimination task. By a wavelet-based time-frequency analysis, age-related theta oscillation response differences were observed within a relatively restricted time range (0-500 ms) over frontal-central regions. Older adults showed stronger theta spectral power during visual and audiovisual stimuli in the left frontal regions; however, young adults showed stronger theta spectral power during auditory and audiovisual stimuli in the central regions. These findings suggest that multisensory oscillatory theta responses differ according to age, which further proves that the left frontal regions play an important role in audiovisual integration.
aSchool of Life Science, Beijing Institute of Technology bSchool of Mechatronics Engineering, Beijing Institute of Technology cThe High School Affiliated to Renmin University of China, Beijing, China dGraduate School of Natural Science and Technology, Okayama University, Okayama, Japan.
Tianyi
T
Yan
Xiaoshan
X
Bi
Mengmeng
M
Zhang
Wenhui
W
Wang
Zhiqi
Z
Yao
Weiping
W
Yang
Jinglong
J
Wu
D000161:Acoustic Stimulation; D000328:Adult; D000368:Aged; D000375:Aging / Q000502:physiology*; D000704:Analysis of Variance; D001307:Auditory Perception / Q000502:physiology*; D001931:Brain Mapping; D004569:Electroencephalography; D005625:Frontal Lobe / Q000502:physiology*; D007839:Functional Laterality / Q000502:physiology; D006801:Humans; D008297:Male; D008875:Middle Aged; D010775:Photic Stimulation; D011930:Reaction Time / Q000502:physiology; D013826:Theta Rhythm / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology*; D055815:Young Adult