Recognizing isolated IgG4-related nephropathy.
IgG4-related tubulointerstitial nephritis is an uncommon cause of renal impairment. It has been associated with dysfunction in a number of other organs giving rise to the term IgG4-related systemic disease; organ involvement can occur metachronously, hence, making it more difficult to identify patients. The exact cause of this condition remains unknown. Here, we present a case of isolated renal involvement which demonstrates how particular biochemical, radiological and histopathological changes should raise the suspicion of IgG4-related nephropathy, especially when there is an absence of clues from any other organ.
Imperial Kidney and Transplantation Centre, Hammersmith Hospital , London W12 0HS , UK.
Rabya
R
Sayed
Imperial Kidney and Transplantation Centre, Hammersmith Hospital , London W12 0HS , UK.
Terence
T
Cook
Imperial Kidney and Transplantation Centre, Hammersmith Hospital , London W12 0HS , UK.
Andrew
A
Palmer
IgG4-related systemic disease; isolated renal involvement; tubulointerstitial nephritis