Amniotic Fluid Embolism: A Rare Complication of Second-Trimester Amniocentesis.
Amniotic fluid embolism occurring following diagnostic amniocentesis is extremely rare. Only 2 cases have been reported in the English literature over the past 55 years, the most recent one approximately 3 decades ago. We present a case of amniocentesis at 24 weeks' gestation that was performed as part of an evaluation of abnormal fetal ultrasound findings. Immediately following amniotic fluid aspiration, maternal hemodynamic collapse occurred, initially diagnosed and treated as anaphylactic shock. Shortly after initial therapy, coagulopathy was noted and amniotic fluid syndrome suspected. Rapid response restored maternal hemodynamic stability; however, the fetus had suffered fatal damage.
Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, affiliated with the Hebrew University Medical School, Jerusalem, Israel.
Lior
L
Drukker
Hen Y
HY
Sela
Alexander
A
Ioscovich
Arnon
A
Samueloff
Sorina
S
Grisaru-Granovsky
D000328:Adult; D000649:Amniocentesis / Q000009:adverse effects*; D000707:Anaphylaxis / Q000175:diagnosis / Q000628:therapy; D003131:Combined Modality Therapy / Q000009:adverse effects; D003937:Diagnosis, Differential; D004211:Disseminated Intravascular Coagulation / Q000209:etiology / Q000517:prevention & control; D004619:Embolism, Amniotic Fluid / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy; D005260:Female; D005313:Fetal Death / Q000209:etiology; D005311:Fetal Hypoxia / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D006801:Humans; D015160:Hydrops Fetalis / Q000000981:diagnostic imaging / Q000209:etiology; D007557:Israel; D011189:Potassium Chloride / Q000506:poisoning; D011247:Pregnancy; D011262:Pregnancy Trimester, Second; D011296:Prenatal Diagnosis; D016896:Treatment Outcome; D016216:Ultrasonography, Prenatal
D011189:Potassium Chloride
Amniocentesis; Amniotic fluid embolus; Amniotic fluid syndrome; Anaphylactic shock; Anaphylaxis; Disseminated intravascular coagulopathy