Chromosome and Plasmids of the Tick-Borne Relapsing Fever Agent Borrelia hermsii.
The zoonotic pathogen Borrelia hermsii bears its multiple paralogous genes for variable antigens on several linear plasmids. Application of combined long-read and short-read next-generation sequencing provided complete sequences for antigen-encoding plasmids as well as other linear and circular plasmids and the linear chromosome of the genome.
Departments of Microbiology & Molecular Genetics, Medicine, and Ecology & Evolutionary Biology, University of California Irvine, Irvine, California, USA abarbour@uci.edu.
Alan G
http://orcid.org/0000-0002-0719-5248
AG
Barbour