[Clinical data analysis of cardiovascular involvement in Behcet's disease].
OBJECTIVE
To analysis the clinical features of cardiovascular involvement in Behcet's disease.


METHODS
We reviewed 35 medical records of Behcet's disease with cardiovascular lesions in Anzhen Hospital, Capital Medical University from January 2002 to January 2014. 77.1% patients (27/35) were male. The mean (x±s) age when cardiovascular diseases occur was 37.19±10.4 years in male and 36.0±8.6 years in female respectively.


RESULTS
The clinical spectrum of cardiovascular abnormalities included valvular regurgitation (20, 57.1%), conduction system disturbances (10, 28.6%), intracardiac thrombosis(1, 2.9%), aneurysms of the arteries (13, 37.1%), artery stenosis or occlusion (5, 14.3%), pulmonary vascular diseases(3, 8.6%), venous thrombosis(4, 11.4%). Twenty patients had more than one of these lesions. Inflammatory indicators had no significantly difference between the above subgroups (P>0.05). Treatments included corticosteroids and immunosuppressive drugs, together with symptomatic treatments, intervention therapy and operation.Two inpatient died from multiple organ dysfunction syndrome and cardiac shock respectively.


CONCLUSIONS
Cardiovascular involvement is a remarkable systemic lesion of Behcet's disease. Multi-subject cooperation is beneficial for the diagnosis and treatment of the disease.
Anzhen Hospital, Capital Medical University, Beijing 100029, China.
N
N
Gao
W
W
Han
W P
WP
Ci
H
H
Liao
J
J
Du
D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000328:Adult; D000783:Aneurysm / Q000175:diagnosis* / Q000601:surgery; D001528:Behcet Syndrome / Q000150:complications* / Q000175:diagnosis / Q000601:surgery / Q000628:therapy; D002318:Cardiovascular Diseases / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy; D003131:Combined Modality Therapy; D005260:Female; D006349:Heart Valve Diseases; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D013927:Thrombosis / Q000175:diagnosis*; D020246:Venous Thrombosis / Q000175:diagnosis / Q000209:etiology
D000305:Adrenal Cortex Hormones; D007166:Immunosuppressive Agents