[The Bridge between Pediatric and Adult Neurology].
Pediatric and adult departments are differentiated based on a cutoff age of approximately 15-17 years. In clinical neurology, there are certain disorders and related problems that overlap these age-determined boundaries. In this review, the following three themes are discussed. (1) Manual dexterity: Considering motor skills through the developmental stages of a child and manual impairment due to localized brain damage in adults, manual dexterity has been reviewed extensively from the perspective of cortical association areas. (2) Hepatolenticular degeneration: Wilson's disease (children) and Westphal-Strümpell pseudosclerosis (adults) are compared and assessed based on the age of onset to identify differences in clinical symptoms and pathological findings. (3) Hirayama disease: This disease has been identified as an adult neurological disorder. Since the onset of Hirayama disease occurs around puberty in children and adolescents, it provides a connecting link between pediatric and adult neurology.
Chiba University.
Keizo
K
Hirayama
D000328:Adult; D017668:Age of Onset; D001921:Brain / Q000503:physiopathology; D002648:Child; D006801:Humans; D009422:Nervous System Diseases / Q000175:diagnosis / Q000503:physiopathology* / Q000628:therapy; D011379:Prognosis