Soft Tissue Sarcoma, Version 2.2016, NCCN Clinical Practice Guidelines in Oncology.
Soft tissue sarcomas (STS) are rare solid tumors of mesenchymal cell origin that display a heterogenous mix of clinical and pathologic characteristics. STS can develop from fat, muscle, nerves, blood vessels, and other connective tissues. The evaluation and treatment of patients with STS requires a multidisciplinary team with demonstrated expertise in the management of these tumors. The complete NCCN Guidelines for Soft Tissue Sarcoma (available at NCCN.org) provide recommendations for the diagnosis, evaluation, and treatment of extremity/superficial trunk/head and neck STS, as well as intra-abdominal/retroperitoneal STS, gastrointestinal stromal tumor, desmoid tumors, and rhabdomyosarcoma. This manuscript discusses guiding principles for the diagnosis and staging of STS and evidence for treatment modalities that include surgery, radiation, chemoradiation, chemotherapy, and targeted therapy.
Margaret
M
von Mehren
R Lor
RL
Randall
Robert S
RS
Benjamin
Sarah
S
Boles
Marilyn M
MM
Bui
Ernest U
EU
Conrad
Kristen N
KN
Ganjoo
Suzanne
S
George
Ricardo J
RJ
Gonzalez
Martin J
MJ
Heslin
John M
JM
Kane
Henry
H
Koon
Joel
J
Mayerson
Martin
M
McCarter
Sean V
SV
McGarry
Christian
C
Meyer
Richard J
RJ
O'Donnell
Alberto S
AS
Pappo
I Benjamin
IB
Paz
Ivy A
IA
Petersen
John D
JD
Pfeifer
Richard F
RF
Riedel
Scott
S
Schuetze
Karen D
KD
Schupak
Herbert S
HS
Schwartz
William D
WD
Tap
Jeffrey D
JD
Wayne
Mary Anne
MA
Bergman
Jillian
J
Scavone
D006801:Humans; D008495:Medical Oncology / Q000592:standards*; D012509:Sarcoma / Q000175:diagnosis* / Q000628:therapy*