Controversies and challenges in the management of chronic urticaria.
This supplement reports proceedings of the second international Global Urticaria Forum, which was held in Berlin, Germany in November 2015. Despite the clear international guideline, there remain a number of controversies and challenges in the management of patients with chronic urticaria (CU). As a result of major advancements in urticaria over the past 4 years, the current EAACI/GA(2) LEN/EDF/WAO urticaria guideline treatment algorithm requires updating. Case studies from patients with chronic spontaneous urticaria (CSU) [also called chronic idiopathic urticaria (CIU)], chronic inducible urticaria (CIndU) or diseases and syndromes related to CU are useful in describing and exploring challenges in disease management. Case studies of specific CSU patient populations such as children with CU or patients with angio-edema but no hives also require consideration as potentially challenging groups with unmet needs. The current EAACI/GA(2) LEN/EDF/WAO urticaria guideline provides a general framework for the management of patients with CU but, as these cases highlight, a personalized approach based on the expert knowledge of the physician may be required.
Department of Dermatology, University Medical Center, Mainz, Germany.
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Staubach
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.
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Zuberbier
Department of Dermatology and Venereology, Aarhus University, Aarhus, Denmark.
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Vestergaard
Department of Dermatology and Allergy, Allergie-Centrum-Charité, Charité - Universitätsmedizin Berlin, Berlin, Germany.
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Siebenhaar
Division of Allergy and Clinical Immunology, Bnai-Zion Medical Center, Haifa, Israel.
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Toubi
Division of Allergy and Clinical Immunology, St. Michael's Hospital and University of Toronto, Toronto, ON, Canada.
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Sussman
D000328:Adult; D000368:Aged; D000799:Angioedema / Q000150:complications / Q000188:drug therapy; D002648:Child; D002908:Chronic Disease; D003080:Cold Temperature; D005260:Female; D006634:Histamine H1 Antagonists / Q000009:adverse effects / Q000627:therapeutic use; D006801:Humans; D008297:Male; D008875:Middle Aged; D010375:Pedigree; D013472:Sunlight; D014581:Urticaria / Q000150:complications / Q000188:drug therapy* / Q000209:etiology
D006634:Histamine H1 Antagonists