Asbestos content of lung tissue in patients with malignant peritoneal mesothelioma: A study of 42 cases.
Lung tissue from 42 peritoneal mesothelioma cases was analyzed by light microscopy and scanning electron microscopy/energy dispersive spectrometry. There were 34 men and 8 women with a mean age of 61 ± 10 years. Also, 17% of cases had histologically confirmed asbestosis, and 26% had only parietal pleural plaques. The asbestos body count exceeded our normal range in 22 of 42 cases (52%). Cases with asbestos-related pulmonary disease had higher fiber burdens than those without. The vast majority of fibers were commercial amphiboles (amosite with lesser amounts of crocidolite). These findings concur with previously published epidemiological observations.
a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
Gustaaf G
GG
de Ridder
a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
Alyssa
A
Kraynie
a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
Elizabeth N
EN
Pavlisko
b Department of Pathology , University of Pittsburgh Medical Center , Pittsburgh , PA , USA.
Tim D
TD
Oury
a Department of Pathology , Duke University Medical Center , Durham , NC , USA.
Victor L
VL
Roggli
D000328:Adult; D000368:Aged; D001195:Asbestosis / Q000150:complications* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008175:Lung Neoplasms / Q000150:complications* / Q000473:pathology; D008297:Male; D008654:Mesothelioma / Q000150:complications* / Q000473:pathology; D000086002:Mesothelioma, Malignant; D008855:Microscopy, Electron, Scanning; D008875:Middle Aged; D010534:Peritoneal Neoplasms / Q000150:complications* / Q000473:pathology; D013052:Spectrometry, X-Ray Emission
Asbestos; lung tissue; malignant peritoneal mesothelioma