One-year outcomes after Absorb bioresorbable vascular scaffold implantation in routine clinical practice.
OBJECTIVE
Our aim was to report one-year outcomes of Absorb bioresorbable scaffold implantation under real-world conditions in an all-comers population of patients with high proportions of complex lesions.


RESULTS
Patients undergoing Absorb 1.1 implantation were included in a single-centre, prospective, all-comers registry. The primary outcome was target lesion failure (TLF), defined as the combination of cardiac death, target vessel myocardial infarction (MI), or clinically driven target lesion revascularisation (TLR). A total of 319 patients received 604 Absorb BVS in 406 lesions. Of note, 24.8% of patients had diabetes and 49.5% presented with an acute coronary syndrome. A total of 51% of lesions were type B2/C. The reference vessel diameter and lesion length were 2.9±0.5 and 21.2±16.8 mm, respectively. The one-year cumulative rate of TLF was 4.9%. Rates of cardiac death, target vessel MI and TLR were 0.9%, 1.3% and 4.2%, respectively. The cumulative one-year rate of definite/probable scaffold thrombosis was 1.3%, with all events occurring within 30 days.


CONCLUSIONS
These data suggest that twelve-month clinical outcomes of Absorb use in "real-world" unselected patients with high proportions of complex lesions are reasonably good.
Cardiovascular Department, Ferrarotto Hospital, University of Catania, Catania, Italy.
Piera
P
Capranzano
Giovanni
G
Longo
Claudia Ina
CI
Tamburino
Giuseppe
G
Gargiulo
Yohei
Y
Ohno
Bruno
B
Francaviglia
Alessio
A
La Manna
Maria Elena
ME
Di Salvo
Carmelo
C
Grasso
Carmelo
C
Sgroi
Davide
D
Capodanno
Corrado
C
Tamburino
D020341:Absorbable Implants / Q000009:adverse effects; D000368:Aged; D000369:Aged, 80 and over; D054855:Drug-Eluting Stents; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000628:therapy*; D062645:Percutaneous Coronary Intervention / Q000379:methods; D011446:Prospective Studies; D011474:Prosthesis Design; D016896:Treatment Outcome