Low-Volume High-Intensity Interval Training as a Therapy for Type 2 Diabetes.
Our purpose was to investigate the effects of low-volume, high-intensity interval training (HIT) on cardiometabolic risk and exercise capacity in women with type 2 diabetes mellitus (T2DM). Sedentary overweight/obese T2DM women (age=44.5±1.8 years; BMI=30.5±0.6 kg/m(2)) were randomly assigned to a tri-weekly running-based HIT program (n=13) or non-exercise control follow-up (CON; n=10). Glycemic control, lipid and blood pressure levels, endurance performance, and anthropometry were measured before and after the follow-up (16 weeks) in both groups. Medication intake was also assessed throughout the follow-up. Improvements (P<0.05) on fasting glucose (14.3±1.4%), HbA1c (12.8±1.1%), systolic blood pressure (3.7±0.5 mmHg), HDL-cholesterol (21.1±2.8%), triglycerides (17.7±2.8%), endurance performance (9.8±1.0%), body weight (2.2±0.3%), BMI (2.1±0.3%), waist circumference (4.0±0.5%) and subcutaneous fat (18.6±1.4%) were found after HIT intervention. Patients of HIT group also showed reductions in daily dosage of antihyperglycemic and antihypertensive medication during follow-up. No changes were found in any variable of CON group. The HIT-induced improvements occurred with a weekly time commitment 56-25% lower than the minimal recommended in current guidelines. These findings suggest that low-volume HIT may be a time-efficient intervention to treat T2DM women.
Cardiovascular Health Program, Centro de Salud Familiar, Los Lagos, Chile.
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Alvarez
Department of Physical Activity Sciences, Universidad de Los Lagos, Osorno, Chile.
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Ramirez-Campillo
Department of Physical Education and Recreation, Faculty of Education, Social Sciences and Humanities, Universidad de la Frontera, Temuco, Chile.
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Martinez-Salazar
Department of Human Movement Science, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, Netherlands.
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Mancilla
Department of Physiology, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria, Australia.
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Flores-Opazo
Rehabilitation, Public Hospital of Los Lagos, Los Lagos, Chile.
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Cano-Montoya
Exercise and Chronic Disease Research Laboratory, Physical Education Department, School of Sciences, São Paulo State Univiersity - UNESP.
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Ciolac
D000328:Adult; D000959:Antihypertensive Agents / Q000627:therapeutic use; D001786:Blood Glucose / Q000032:analysis; D001794:Blood Pressure; D001835:Body Weight; D003924:Diabetes Mellitus, Type 2 / Q000628:therapy*; D005081:Exercise Therapy; D005260:Female; D000072696:High-Intensity Interval Training; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008055:Lipids / Q000097:blood; D008875:Middle Aged; D009765:Obesity / Q000097:blood; D050177:Overweight / Q000097:blood; D010807:Physical Endurance; D055105:Waist Circumference
D000959:Antihypertensive Agents; D001786:Blood Glucose; D007004:Hypoglycemic Agents; D008055:Lipids