Pure and Mixed Mucinous Carcinoma of the Breast: A Comparison of Clinical Outcomes and Treatment Results.
Mucinous breast carcinoma (MBC) carcinoma represents approximately 1-6% of all malignant breast carcinoma and is divided into pure (PMBC) and mixed (MMBC) subtypes. This study presents the comparison of clinical characteristics and treatment results in 70 patients with PMBC and 40 patients with MMBC, treated at a single institution during 25 years. Performed analyses showed that only nodal status was different in both subtypes. Patients with MMBC showed a significantly higher incidence of axillary nodal metastases in comparison to PMBC (25% versus 10%, respectively). Instead, the 10-year disease-free survival rate was significant higher in PMBC than MMBC (85.7% versus 65%, p < 0.02, test log rank). Authors own observations and data from literature proved that MMBC should be considered as subtypes of mucinous breast cancer.
Department of Surgical Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Piotr
P
Skotnicki
Department of Clinical Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Beata
B
Sas-Korczynska
Department of Surgical Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Lukasz
L
Strzepek
Department of Clinical Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Jerzy
J
Jakubowicz
Department of Gynaecological Oncology, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Pawel
P
Blecharz
Department of Radiotherapy, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Marian
M
Reinfuss
Department of Radiotherapy, Maria Sklodowska-Curie, Memorial Cancer Centre and Institute of Oncology, Krakow, Poland.
Tomasz
T
Walasek
D002288:Adenocarcinoma, Mucinous / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000401:mortality / Q000473:pathology* / Q000628:therapy*; D059186:Chemoradiotherapy, Adjuvant; D018572:Disease-Free Survival; D019583:Dose Fractionation, Radiation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008408:Mastectomy; D008875:Middle Aged; D012189:Retrospective Studies; D016896:Treatment Outcome
breast cancer; mixed mucinous carcinoma; pure mucinous carcinoma