[Dementia with motor and language disorders].
Memory is not the only core diagnostic criteria in Alzheimer's disease and many dementias are characterized by other cognitive deficits. Moreover dementias are often associated with multiple and complex motor signs. The first part of this reviewcovers parkinsonism in diffuse Lewy Body Disease and other neurodegenerative diseases, corticobasal syndrome, or motor deficit in the motoneurone disease-frontotemporal dementia spectrum. In the second part, primary progressive aphasia and its three variants including basic clinical evaluation are described. These complex clinical syndromes involving motor and language systems are important for the clinical practice since they are part of diagnostic criteria of several neurodegenerative diseases and can be considered as phenotypical markers of neurodegeneration.
Assal
A
Frédéric
Joseph
J
Ghika
D000544:Alzheimer Disease / Q000175:diagnosis; D001037:Aphasia / Q000209:etiology; D003072:Cognition Disorders / Q000209:etiology; D003704:Dementia / Q000150:complications* / Q000175:diagnosis*; D003937:Diagnosis, Differential; D057180:Frontotemporal Dementia / Q000150:complications / Q000175:diagnosis; D006801:Humans; D007806:Language Disorders / Q000209:etiology*; D020961:Lewy Body Disease / Q000175:diagnosis; D000068079:Motor Disorders / Q000209:etiology*; D019636:Neurodegenerative Diseases / Q000175:diagnosis; D009483:Neuropsychological Tests; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis