Nutrient Intakes in Early Life and Risk of Obesity.
There is increasing evidence that environmental factors in early life predict later health. The early adiposity rebound recorded in most obese subjects suggests that factors promoting body fat development have operated in the first years of life. Birth weight, growth velocity and body mass index (BMI) trajectories seem to be highly sensitive to the environmental conditions present during pregnancy and in early life ("The first 1000 days"). Particularly, nutritional exposure can have a long-term effect on health in adulthood. The high protein-low fat diet often recorded in young children may have contributed to the rapid rise of childhood obesity prevalence during the last decades. Metabolic programming by early nutrition could explain the development of later obesity and adult diseases.
Universit&#233; Paris 13, Equipe de Recherche en Epid&#233;miologie Nutritionnelle, Centre de Recherche en Epid&#233;miologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cit&#233;, Bobigny F-93017, France. mf.cachera@uren.smbh.univ-paris13.fr.
Marie Françoise
MF
Rolland-Cachera
Universit&#233; Paris 13, Equipe de Recherche en Epid&#233;miologie Nutritionnelle, Centre de Recherche en Epid&#233;miologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cit&#233;, Bobigny F-93017, France. mounakrout@yahoo.fr.
Mouna
M
Akrout
Universit&#233; Paris 13, Equipe de Recherche en Epid&#233;miologie Nutritionnelle, Centre de Recherche en Epid&#233;miologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cit&#233;, Bobigny F-93017, France. s.peneau@uren.smbh.univ-paris13.fr.
Sandrine
S
Péneau
D050154:Adiposity / Q000502:physiology*; D000293:Adolescent; D000328:Adult; D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D002648:Child; D002675:Child, Preschool; D002149:Energy Intake / Q000502:physiology*; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D009752:Nutritional Status / Q000502:physiology*; D063766:Pediatric Obesity / Q000503:physiopathology*; D011247:Pregnancy; D012307:Risk Factors; D015430:Weight Gain / Q000502:physiology*
adiposity rebound; child’s growth; early nutrition; epidemiology; leptin; metabolic programming; obesity; secular trends