Electrochemically assisted deposition of strontium modified magnesium phosphate on titanium surfaces.
Electrochemically assisted deposition was utilized to produce ceramic coatings on the basis of magnesium ammonium phosphate (struvite) on corundum-blasted titanium surfaces. By the addition of defined concentrations of strontium nitrate to the coating electrolyte Sr(2+) ions were successfully incorporated into the struvite matrix. By variation of deposition parameters it was possible to fabricate coatings with different kinetics of Sr(2+) into physiological media, whereas the release of therapeutically relevant strontium doses could be sustained over several weeks. Morphological and crystallographic examinations of the immersed coatings revealed that the degradation of struvite and the release of Sr(2+) ions were accompanied by a transformation of the coating to a calcium phosphate based phase similar to low-crystalline hydroxyapatite. These findings showed that strontium doped struvite coatings may provide a promising degradable coating system for the local application of strontium or other biologically active metal ions in the implant-bone interface.
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany.
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M
Meininger
Max Bergmann Center for Biomaterials, Technical University of Dresden, Budapester Straße 27, D-01069 Dresden, Germany.
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C
Wolf-Brandstetter
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany.
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J
Zerweck
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany.
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F
Wenninger
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany.
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Gbureck
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany.
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J
Groll
Department for Functional Materials in Medicine and Dentistry, University of Würzburg, Pleicherwall 2, D-97070 Würzburg, Germany. Electronic address: claus.moseke@fmz.uni-wuerzburg.de.
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Moseke
D020099:Coated Materials, Biocompatible / Q000737:chemistry*; D017616:Magnesium Compounds / Q000737:chemistry*; D010710:Phosphates / Q000737:chemistry*; D013324:Strontium / Q000737:chemistry*; D013499:Surface Properties; D014025:Titanium / Q000737:chemistry*
D020099:Coated Materials, Biocompatible; D017616:Magnesium Compounds; D010710:Phosphates; C030781:magnesium phosphate; D014025:Titanium; D013324:Strontium
Biomaterials; Coating; Electrochemistry; Implant; Strontium; Struvite; Surface modification