Merkel cell carcinoma in a vein graft donor site.
The development of malignancies in graft donor sites is rare and may be caused by de novo malignancies as well as metastatic and iatrogenic spread. Malignancies in graft donor sites are distinguished from Marjolin ulcers by some investigators because they occur in healed surgical wounds rather than in chronic wounds or unstable scars and tend to occur sooner after injury. We present a unique case of Merkel cell carcinoma (MCC) developing in a vein graft donor site 18 years after vein harvesting.
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, USA.
Jennifer S
JS
Ranario
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, USA.
Amanda J
AJ
Wolthoff
Lubbock Dermatology and Skin Cancer Center, Texas, USA.
Richard H
RH
Hope
Department of Dermatology, Texas Tech University Health Sciences Center, Lubbock, USA.
Cloyce L
CL
Stetson
Covenant Medical Center, Lubbock, Texas, USA.
Catherine A
CA
Ronaghan
D000368:Aged; D015266:Carcinoma, Merkel Cell / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D002921:Cicatrix / Q000209:etiology / Q000473:pathology; D004210:Dissection / Q000379:methods*; D006801:Humans; D008297:Male; D009367:Neoplasm Staging; D011878:Radiotherapy / Q000379:methods*; D012878:Skin Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000503:physiopathology / Q000628:therapy; D016896:Treatment Outcome; D058017:Vascular Grafting / Q000009:adverse effects*