Association between the Type of Workplace and Lung Function in Copper Miners.
The aim of the analysis was to retrospectively assess changes in lung function in copper miners depending on the type of workplace. In the groups of 225 operators, 188 welders, and 475 representatives of other jobs, spirometry was performed at the start of employment and subsequently after 10, 20, and 25 years of work. Spirometry Longitudinal Data Analysis software was used to estimate changes in group means for FEV1 and FVC. Multiple linear regression analysis was used to assess an association between workplace and lung function. Lung function assessed on the basis of calculation of longitudinal FEV1 (FVC) decline was similar in all studied groups. However, multiple linear regression model used in cross-sectional analysis revealed an association between workplace and lung function. In the group of welders, FEF75 was lower in comparison to operators and other miners as early as after 10 years of work. Simultaneously, in smoking welders, the FEV1/FVC ratio was lower than in nonsmokers (p < 0,05). The interactions between type of workplace and smoking (p < 0,05) in their effect on FVC, FEV1, PEF, and FEF50 were shown. Among underground working copper miners, the group of smoking welders is especially threatened by impairment of lung ventilatory function.
Department of Internal and Occupational Diseases and Hypertension, Wrocław Medical University, Borowska 213, 50-556 Wrocław, Poland.
Anna
0000-0002-1699-8448
A
Skoczyńska
The Copper Health Center, M. Skłodowskiej-Curie 66, 59-301 Lubin, Poland.
Leszek
L
Gruszczyński
Department of Internal and Occupational Diseases and Hypertension, Wrocław Medical University, Borowska 213, 50-556 Wrocław, Poland.
Anna
A
Wojakowska
The Copper Health Center, M. Skłodowskiej-Curie 66, 59-301 Lubin, Poland.
Marek
M
Ścieszka
Department of Internal and Occupational Diseases and Hypertension, Wrocław Medical University, Borowska 213, 50-556 Wrocław, Poland.
Barbara
B
Turczyn
The Copper Health Center, M. Skłodowskiej-Curie 66, 59-301 Lubin, Poland.
Edward
E
Schmidt
D000328:Adult; D003300:Copper / Q000633:toxicity*; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000503:physiopathology; D008171:Lung Diseases / Q000139:chemically induced / Q000453:epidemiology / Q000503:physiopathology*; D008297:Male; D000067572:Miners; D009569:Nitric Oxide / Q000633:toxicity*; D016273:Occupational Exposure; D018384:Oxidative Stress / Q000187:drug effects; D026361:Reactive Nitrogen Species / Q000378:metabolism
D026361:Reactive Nitrogen Species; D009569:Nitric Oxide; D003300:Copper