Tracking Protein S-Fatty Acylation with Proteomics.
Recently, Hang and co-workers developed "acyl-PEG exchange" (APE), which allows the investigation of protein S-fatty acylation with mass-tag labelling and gel electrophoresis, methods that are accessible to any biochemistry laboratory.
Research Unit Functional Proteomics and Metabolic Pathways, Institute of Pathology, Medical University Graz and, Omics Center Graz, BioTechMed-Graz, Stiftintalstrasse 24, 8010, Graz, Austria.
Ruth
0000-0003-3950-0312
R
Birner-Gruenberger
Institute of Organic Chemistry, BioTechMed-Graz, Graz University of Technology, Stremayrgasse 9, 8010, Graz, Austria. breinbauer@tugraz.at.
Rolf
0000-0001-6009-7359
R
Breinbauer
D000215:Acylation; D005227:Fatty Acids / Q000737:chemistry / Q000378:metabolism*; D006801:Humans; D015394:Molecular Structure; D017293:Protein S / Q000737:chemistry / Q000378:metabolism*; D040901:Proteomics
D005227:Fatty Acids; D017293:Protein S
cysteine; lipoproteins; palmitoylation; post-translational modification; proteomics