Synthesis of β,β-diaryl propiophenones via palladium-catalyzed domino arylboronation, elimination and enone hydroarylation of enaminones.
The syntheses of β,β-diaryl aryl propiophenones have been realized via palladium-catalyzed domino reactions of dimethyl amino functionalized enaminones and aryl boronic acids. This is the first example of transition metal-catalyzed enaminone C-N bond conversion for the generation of a new C-C(aryl) structure.
College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022, P.R. China. wanjieping@jxnu.edu.cn.
Shanshan
S
Zhong
Yu
Y
Lu
Yan
Y
Zhang
Yunyun
Y
Liu
Jie-Ping
JP
Wan