Chronic kidney disease-mineral and bone disorder: Guidelines for diagnosis, treatment, and management.
Chronic kidney disease affects 23 million Americans and is associated with many complications, one of the most complex of which is mineral and bone disorder. Pathophysiologic mechanisms begin to occur early in CKD but when the glomerular filtration rate declines to <50% of normal, biochemical and bone matrix abnormalities, which vary and are multifactorial, begin to be clinically apparent. Mainstays of treatment remain management of hyperphosphatemia and prevention or treatment of secondary hyperparathyroidism.
Carla Moschella conducts continuing medical education seminars across the country on nephrology, gastroenterology, and laboratory medicine topics and provides physical and mental health assessments for military service members for a company that contracts with the US Department of Defense. The author has disclosed no potential conflicts of interest, financial or otherwise.
Carla
C
Moschella
D012080:Chronic Kidney Disease-Mineral and Bone Disorder / Q000175:diagnosis / Q000628:therapy; D005919:Glomerular Filtration Rate; D006801:Humans; D006962:Hyperparathyroidism, Secondary; D054559:Hyperphosphatemia; D017410:Practice Guidelines as Topic; D051436:Renal Insufficiency, Chronic