Characterization of cervical lymph nodes using DCE-MRI: Differentiation between metastases from SCC of head and neck and benign lymph nodes.
OBJECTIVE
To compare the characteristics of DCE-MRI between metastatic and benign lymph nodes (LNs). To explore the effect of sizes of LNs on the value of Ktrans, Ve and iAUC.


METHODS
Metastatic and benign LNs were retrospectively analyzed. Chi-square test and two sample t-test were applied to TICs and parameters. One factor covariance analysis was used to explore the effect of diameters on the value of Ktrans, Ve and iAUC.


RESULTS
The value of Ktrans, Ve and iAUC of metastatic LNs were statistically higher (all p < 0.001) than those of benign LNs. The short-axis diameters had no influence on parameters.


CONCLUSIONS
DCE-MRI is useful to differentiate the metastatic LNs from benign LNs. Sizes of LNs has no effect on parameters.
Department of Radiology, Beijing Ditan Hospital, Capital Medical University, China.|Department of Radiology, Tianjin First Central Hospital, China.
Shuo
S
Yan
Department of Radiology, Yuhuang Ding Hospital, China.
Zhiye
Z
Wang
Department of Otolaryngology-Head and Neck Surgery, Tianjin First Central Hospital, China.
Li
L
Li
Department of Radiology, Tianjin First Central Hospital, China.
Yu
Y
Guo
Department of Radiology, Tianjin First Central Hospital, China.
Xiaodong
X
Ji
Department of Radiology, Tianjin First Central Hospital, China.
Hongyan
H
Ni
Department of Radiology, Tianjin First Central Hospital, China.
Wen
W
Shen
Department of Radiology, Tianjin First Central Hospital, China.
Shuang
S
Xia
D002294:Carcinoma, Squamous Cell / Q000401:mortality / Q000473:pathology*; D002574:Cervical Vertebrae; D006258:Head and Neck Neoplasms / Q000401:mortality / Q000473:pathology*; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008875:Middle Aged; D012189:Retrospective Studies; D015996:Survival Rate
Dynamic contrast-enhanced magnetic resonance imaging; head and neck squamous cell carcinoma; lymph node