Giant seminoma in an undescended testicle metastasizing to the neck and liver.
Germ cell tumors account for 98% of all testicular malignancies. Delays in seeking treatment are unfortunately common and may lead to metastatic spread. The present study reported a case of a 24-year-old man with a giant 12×10 cm left inguinal mass and a left neck mass that had grown rapidly during recent months. Computed tomography confirmed that the mass measured 12.1×9.4 cm and was a left undescended testicle malignancy, and also revealed widespread metastasis to the liver and a large retroperitoneal mass (12.6×8.2 cm). Immunohistochemical staining confirmed seminoma. The patient was treated with chemotherapy with the VIP protocol (cisplatin, etoposide and ifosfamide). Following courses of chemotherapy, the patient received complete clinical remission and was disease-free at the 6 month follow-up.
Department of Andrology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Kai-Min
KM
Guo
Department of Radiology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Yang
Y
Liu
Department of Pathology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Yan-Ping
YP
Zhong
Department of Andrology, The First Hospital of Jilin University, Changchun, Jilin 130021, P.R. China.
Hong-Liang
HL
Wang
chemotherapy; complete remission; cryptorchidism; late metastasis; seminoma