Associations between antithrombotic therapy and the risk of perioperative complications among patients undergoing laparoscopic gastrectomy.
The aim of this study was to identify factors associated with perioperative morbidity among patients who underwent laparoscopic gastrectomy while receiving antithrombotic therapy (ATT).



This retrospective cohort study included 46 patients (14 females and 32 males) who underwent laparoscopic gastrectomy, including 12 (26.1 %) who received perioperative ATT, between January 2012 and November 2015 in our institution. Among patients receiving only aspirin as antiplatelet therapy, none were on anticoagulation therapy. All patients took aspirin as antiplatelet therapy for cardiac indications. The clinical findings and surgical outcomes of patients who did (ATT group) and did not (control group) receive ATT were compared.



The intraoperative mortality was 0 % for both groups. There was no significant difference in the incidence of postoperative morbidity by univariate analysis between the control and ATT groups (8.8 vs. 8.3 %, p = 0.39).



The risk of postoperative morbidity of laparoscopic gastrectomy can be equivalent between the ATT and non-ATT (control) groups.
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan. kodaiyy@hotmail.co.jp.
Kodai
K
Takahashi
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Hideto
H
Ito
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Toshio
T
Katsube
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Ayaka
A
Tsuboi
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Masatoshi
M
Hashimoto
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Emi
E
Ota
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Kazuhito
K
Mita
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Hideki
H
Asakawa
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Takashi
T
Hayashi
Department of Surgery, New-Tokyo Hospital, 1271 Wanagaya Matsudo-city, Chiba, 270-2232, Japan.
Keiichi
K
Fujino
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001241:Aspirin / Q000009:adverse effects; D016063:Blood Loss, Surgical / Q000706:statistics & numerical data*; D005260:Female; D005343:Fibrinolytic Agents / Q000009:adverse effects*; D005743:Gastrectomy / Q000379:methods / Q000401:mortality; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D019990:Perioperative Care / Q000009:adverse effects*; D011183:Postoperative Complications / Q000139:chemically induced* / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors
D005343:Fibrinolytic Agents; D001241:Aspirin
Antiplatelet therapy; Antithrombotic therapy; Laparoscopic gastrectomy; Morbidity