Discrepancies between selected Pareto optimal plans and final deliverable plans in radiotherapy multi-criteria optimization.
Multi-criteria optimization provides decision makers with a range of clinical choices through Pareto plans that can be explored during real time navigation and then converted into deliverable plans. Our study shows that dosimetric differences can arise between the two steps, which could compromise the clinical choices made during navigation.
Institute of Radiation Physics (IRA), Lausanne University Hospital, Switzerland.
Archonteia
A
Kyroudi
Institute of Radiation Physics (IRA), Lausanne University Hospital, Switzerland.
Kristoffer
K
Petersson
Department of Radiation Oncology, Hôpital Riviera-Chablais, Vevey, Switzerland.
Sarah
S
Ghandour
Department of Radiation Oncology, Hôpital Riviera-Chablais, Vevey, Switzerland.
Marc
M
Pachoud
Department of Radiation Oncology, Hôpital Riviera-Chablais, Vevey, Switzerland.
Oscar
O
Matzinger
Department of Radiation Oncology, Lausanne University Hospital, Switzerland.
Mahmut
M
Ozsahin
Department of Radiation Oncology, Lausanne University Hospital, Switzerland.
Jean
J
Bourhis
Institute of Radiation Physics (IRA), Lausanne University Hospital, Switzerland.
François
F
Bochud
Institute of Radiation Physics (IRA), Lausanne University Hospital, Switzerland.
Raphaël
R
Moeckli
D002289:Carcinoma, Non-Small-Cell Lung / Q000532:radiotherapy*; D006801:Humans; D008175:Lung Neoplasms / Q000532:radiotherapy*; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy*; D011874:Radiometry; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods* / Q000592:standards; D050397:Radiotherapy, Intensity-Modulated; D012189:Retrospective Studies
Deliverable; Multi-criteria optimization; Navigated; Pareto fronts