Metal free TBHP-promoted intramolecular carbonylation of arenes via radical cross-dehydrogenative coupling: synthesis of indenoquinolinones, 4-azafluorenones and fluorenones.
A metal-free, TBHP-promoted economical route is developed via the sp(2) C-H bond functionalization strategy for the synthesis of indenoquinolinones, 4-azafluorenones and fluorenones. Reactions provided excellent yield of the products under mild conditions. We have successfully synthesized 11H-indeno[1,2-b]quinolin-11-one, an antibacterial agent, in excellent yields.
Department of Chemistry, Centre of Advanced Studies, Institute of Science, Banaras Hindu University, Varanasi-221005, India. rmohan@bhu.ac.in.
Kalpana
K
Mishra
Ashok Kumar
AK
Pandey
Jay Bahadur
JB
Singh
Radhey M
RM
Singh
D001372:Aza Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D047250:Calixarenes / Q000737:chemistry*; D005449:Fluorenes / Q000138:chemical synthesis* / Q000737:chemistry; D006865:Hydrogenation; D015394:Molecular Structure; D020122:tert-Butylhydroperoxide / Q000737:chemistry*
D001372:Aza Compounds; D005449:Fluorenes; D047250:Calixarenes; D020122:tert-Butylhydroperoxide