Identification of a new HLA-G allele, HLA-G*01:19, by cloning and phasing.
A new HLA-G allelic variant, HLA-G*01:19, was identified in a southern Chinese Han population by polymerase chain reaction-sequence-based typing (PCR-SBT), cloning and phasing. HLA-G*01:19 differs from HLA-G*01:04:01 by a nonsynonymous cytosine at position 99 in exon 2, resulting in amino acid change from valine to leucine at codon 34 of the mature HLA-G molecule.
Immunogenetics Research Group, Department of Immunology, College of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
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Wang
Immunogenetics Research Group, Department of Immunology, College of Basic Medical Sciences, Central South University, Changsha, Hunan, China.|Laboratory of Cellular and Molecular Biology, College of Basic Medical Sciences, Central South University, Changsha, Hunan, China.
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Tian
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics / Q000276:immunology; D044466:Asian People; D001483:Base Sequence; D003001:Cloning, Molecular; D005091:Exons / Q000235:genetics* / Q000276:immunology; D059951:HLA-G Antigens / Q000235:genetics* / Q000276:immunology / Q000302:isolation & purification; D006801:Humans; D007930:Leucine / Q000276:immunology; D014633:Valine / Q000235:genetics
D059951:HLA-G Antigens; D007930:Leucine; D014633:Valine