Stigma as a key determinant of health-related quality of life in Parkinson's disease.
People with Parkinson's disease (PD) may experience stigma due to their visible features of movement and communication difficulties. This paper aimed to examine the role of experienced stigma in health-related quality of life (QOL), after controlling for personal and clinical characteristics.



This is a preliminary analysis of a subset of baseline data from the Social Self-Management of Parkinson's Disease Study (SocM-PD), an ongoing 3-year prospective cohort study. Seventy-three people with PD (Mage= 65.72, 29 women) participated in this study. Hierarchical multiple regression analyses were used to determine the role of stigma in QOL, after controlling for gender, disease severity, depression, and motor difficulties of daily living.



Significant correlations were found between QOL with gender (r = .26), disease severity (r = .38), depression (r = .65), motor difficulties of daily living (r = .71), and stigma (r = .83). After controlling for the significant covariates, stigma made a significant and unique contribution to the explanation of QOL by 13.7 % (p < 0.001). A final hierarchical multiple regression with stigma and the 4 covariates revealed an overall model that explained 77.8 % of the total variance of QOL (F [5, 63] = 48.79, p < 0.001).



Experienced stigma appears to be a key determinant of QOL in people with PD. The results suggest the importance of further understanding stigma in PD to develop possible intervention strategies. Future work is also needed to verify the results with a larger and longitudinal dataset of the SocM-PD.
Department of Occupational Therapy, College of Medicine, National Cheng Kung University, 1 University Road, Tainan, 701, Taiwan. huingma@mail.ncku.edu.tw.|Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan. huingma@mail.ncku.edu.tw.
Hui-Ing
HI
Ma
Department of Neurology, Parkinson's Disease and Movement Disorders Center, Boston University Medical School, Boston Medical Center, Boston, MA, USA.
Marie
M
Saint-Hilaire
Department of Neurology, Parkinson's Disease and Movement Disorders Center, Boston University Medical School, Boston Medical Center, Boston, MA, USA.
Cathi A
CA
Thomas
Department of Occupational Therapy, School of Arts and Sciences, Tufts University, Medford, MA, USA.
Linda
L
Tickle-Degnen
D000368:Aged; D015331:Cohort Studies; D005260:Female; D006801:Humans; D008297:Male; D010300:Parkinson Disease / Q000523:psychology*; D011446:Prospective Studies; D018434:Sickness Impact Profile
Enacted stigma; Felt stigma; Health-related quality of life; Parkinson’s disease