Vascularity of gastric carcinoma: evaluation using color Doppler ultrasonography.
OBJECTIVE
The purpose of this study was to investigate the vascularity of primary gastric cancer lesions using color Doppler ultrasonography.


METHODS
We used color Doppler ultrasonography to study 78 patients with gastric cancer detected on B-mode ultrasonographic examination and 14 patients without gastric tumors but with a slightly thickened gastric wall that was also detected on B-mode ultrasound. The color Doppler signals of the gastric lesions were graded as (-), no color signals; (+), slight increase in number of color signals; and (++), an obvious increase in number of color signals. The vessel area outside the tumor area in the microscopic pathological specimens was also calculated.


RESULTS
The color signals of 13 (18%) of the 71 gastric cancer patients were graded (-); those of 14 (20%) patients were graded (+); and those of 44 (62%) patients were graded (++). The color signals for 9 (65%) of 14 patients without gastric tumors were graded (-); those of 4 (28%) patients were graded (+), and those of 1 patient (7%) were graded (++). These differences were significant (P = 0.0002). The vessel count ratio in the microscopic pathologic specimens was also significantly higher in patients with an increased number of color signals than in those without an increased number of color signals (P = 0.002).


CONCLUSIONS
Color Doppler ultrasound showed increased vascularity in the gastric cancers in most of the subjects (82%, 58/71). Furthermore, color Doppler ultrasound also showed no increase in vascularity in most subjects (65%, 9/14) whose B-mode ultrasonograms showed thickened gastric walls but who did not have gastric cancer. Thus, color Doppler imaging may prove useful as a screening modality for gastric cancer.
Abdominal Ultrasound Unit, Kinki University School of Medicine, Osaka-Sayama, Japan.
Ai
A
Kuwaguchi
Department of Gastroenterology and Hepatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, 589-8511, Japan. m-kudo@med.kindai.ac.jp.
Masatoshi
M
Kudo
Department of Gastroenterology and Hepatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, 589-8511, Japan.
Toshihiko
T
Kawasaki
Abdominal Ultrasound Unit, Kinki University School of Medicine, Osaka-Sayama, Japan.
Tomoko
T
Maeno
Abdominal Ultrasound Unit, Kinki University School of Medicine, Osaka-Sayama, Japan.
Mayumi
M
Ichijima
Abdominal Ultrasound Unit, Kinki University School of Medicine, Osaka-Sayama, Japan.
Kiyoshi
K
Maekawa
Department of Gastroenterology and Hepatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama, 589-8511, Japan.
Tatsuo
T
Inoue
Department of Pathology, Kinki University School of Medicine, Osaka-Sayama, Japan.
Tatsuki
T
Ito
color Doppler imaging; gastric cancer; ultrasonography