Effect of the stiffness of bone substitutes on the biomechanical behaviour of femur for core decompression.
Core decompression is the most common procedure for treatment of the early stages of osteonecrosis of the femoral head. The purpose of this study was to compare the biomechanical performance of four different bone graft substitutes combined with core decompression. Subject-specific finite element models generated from computed tomography (CT) scan data were used for a comprehensive analysis. Two different contact conditions were simulated representing states of osseointegration at the interface. Our results showed that the use of a low-stiffness bone substitute did not increase the risk of femoral fracture in the early postoperative phase, but resulted in less micromotion and interfacial stresses than high-stiffness bone substitutes.
Department of Orthopaedics, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany; Chair of Mechanics and Robotics, University of Duisburg-Essen, Lotharstr. 1, 47045 Duisburg, Germany.
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Tran
Chair of Mechanics and Robotics, University of Duisburg-Essen, Lotharstr. 1, 47045 Duisburg, Germany.
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Kowalczyk
Institute of Anatomy, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany.
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Hohn
Department of Orthopaedics, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany.
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Jäger
Department of Orthopaedics, University Hospital Essen, University of Duisburg-Essen, Hufelandstr. 55, 45147 Essen, Germany. Electronic address: stefan.landgraeber@uk-essen.de.
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Landgraeber
D018786:Bone Substitutes; D005264:Femoral Fractures / Q000150:complications; D005269:Femur; D005271:Femur Head Necrosis / Q000150:complications / Q000000981:diagnostic imaging / Q000628:therapy*; D020342:Finite Element Analysis; D006801:Humans; D055595:Mechanical Phenomena; D066230:Patient-Specific Modeling; D014057:Tomography, X-Ray Computed
D018786:Bone Substitutes
Bone substitute; Core decompression; Femoral head necrosis; Finite element simulation; Fracture risk; Interfacial stress; Micromotion