Familial frontal fibrosing alopecia treated with dutasteride, minoxidil and artificial hair transplantation.
A 46-year-old premenopausal woman presented with familial frontal fibrosis alopecia affecting the temples bilaterally. The diagnosis was confirmed histologically. Her past history included rheumatoid arthritis treated with hydroxychloroquine 400 mg daily and methotrexate 20 mg weekly. Serial intralesional injections of triamcinolone did not limit the progression of hair loss. Treatment with dutasteride 0.1 mg daily and minoxidil 1 mg daily stabilised hair loss and artificial fibre hair transplantation initially led to a satisfactory cosmetic outcome. Unfortunately, the patient developed implant folliculitis uncontrolled by antibiotics, necessitating the removal of the fibres 12 months post-transplantation.
Department of Medicine, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
William C
WC
Cranwell
Department of Medicine, University of Melbourne, Melbourne, Victoria, Australia.|Department of Dermatology, Epworth Dermatology, Melbourne, Victoria, Australia.|Department of Dermatology, Sinclair Dermatology, Melbourne, Victoria, Australia.
Rodney
R
Sinclair
D058891:5-alpha Reductase Inhibitors / Q000627:therapeutic use*; D000505:Alopecia / Q000235:genetics / Q000628:therapy*; D000068538:Dutasteride / Q000627:therapeutic use*; D005260:Female; D005355:Fibrosis; D005499:Folliculitis / Q000209:etiology; D005546:Forehead; D006801:Humans; D008875:Middle Aged; D008914:Minoxidil / Q000627:therapeutic use*; D019736:Prostheses and Implants / Q000009:adverse effects; D014665:Vasodilator Agents / Q000627:therapeutic use*
D058891:5-alpha Reductase Inhibitors; D014665:Vasodilator Agents; D008914:Minoxidil; D000068538:Dutasteride
artificial hair transplantation; dutasteride; familial; frontal fibrosing alopecia; minoxidil