Ingenol mebutate for pigmented superficial basal cell carcinomas: evaluation by confocal microscopy.
The incidence of nonmelanoma skin cancer continues to increase. Surgical excision remains the best choice of treatment but the demand of patients is to have tissue-sparing approaches with good cosmetic results; these aims led to the development of novel therapeutic agents such as topical ingenol mebutate gel. We report the successful treatment with ingenol mebutate gel 0.05% of three pigmented basal cell carcinomas. Lesions were evaluated by dermoscopy and confocal microscopy before, during and after the treatment.
Unit of Dermatology, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Giuseppe
G
Monfrecola
Unit of Dermatology, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Massimiliano
M
Scalvenzi
Unit of Dermatology, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Claudia
C
Costa
Unit of Dermatology, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy - mariateresacantelli@gmail.com.
Mariateresa
M
Cantelli
Unit of Dermatology, Department of Clinical Medicine and Surgery, University Federico II, Naples, Italy.
Gabriella
G
Fabbrocini
D000970:Antineoplastic Agents / Q000008:administration & dosage*; D002280:Basal Cell Carcinoma / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D046169:Dermoscopy; D004224:Diterpenes / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D008297:Male; D018613:Microscopy, Confocal; D008875:Middle Aged; D012878:Skin Neoplasms / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000473:pathology; D016896:Treatment Outcome
C486592:3-ingenyl angelate; D000970:Antineoplastic Agents; D004224:Diterpenes