[Treatment options of non-melanoma skin tumors in organ transplant recipients in relation to a case report].
The authors present the case of a 59-year-old male patient, whose first kidney transplantation was in 1983 and the second in 2000. The first squamous cell carcinoma appeared on the skin 2 years after the first transplantation. Since 2003, at least two precancerous lesions or non-melanoma skin tumors have been removed surgically yearly. These cancers appeared predominantly on the sun-exposed skin, and were multiple. As these tumors could behave aggressively and prone to recurrence, complex treatment was applied, which included a switch in immunosuppressive drugs and the application of field therapies. The authors give an overview of these treatment options in relation to the case presentation, emphasizing that not only early detection and active treatment of the precancerous lesions and skin cancers are essential, but education of proper sun-protection methods and dermatology care are also important in order to avoid the development of these tumors.
Bőrgyógyászati Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.
Emese
E
Gellén
Bőrgyógyászati Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.
Zoltán
Z
Péter
Bőrgyógyászati Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.
Gabriella
G
Emri
Sebészeti Intézet, Szervtranszplantációs Nem Önálló Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen.
László
L
Asztalos
Bőrgyógyászati Tanszék, Debreceni Egyetem, Általános Orvostudományi Kar Debrecen, Nagyerdei krt. 98., 4032.
Éva
É
Remenyik
D002280:Basal Cell Carcinoma / Q000517:prevention & control / Q000601:surgery / Q000628:therapy*; D002294:Carcinoma, Squamous Cell / Q000517:prevention & control / Q000601:surgery / Q000628:therapy*; D003452:Cryosurgery; D004334:Drug Administration Schedule; D055088:Early Detection of Cancer; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects*; D016030:Kidney Transplantation; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000628:therapy; D011230:Precancerous Conditions / Q000175:diagnosis / Q000601:surgery; D012307:Risk Factors; D012878:Skin Neoplasms / Q000517:prevention & control / Q000601:surgery / Q000628:therapy*; D013472:Sunlight / Q000009:adverse effects; D066027:Transplant Recipients
D007166:Immunosuppressive Agents
field cancerization; field therapy; fotodinámiás terápia; immunosuppressive drugs; immunszuppresszív terápia; kidney transplantation; mezőkarcinogenezis; mezőterápia; non-melanoma skin cancer; nonmelanoma bőrdaganat; photodynamic therapy; veseátültetés