Mycophenolate Mofetil in Severe Atopic Dermatitis: A Review.
Atopic Dermatitis (AD) is a chronic inflammatory skin disease that is a significant cause of morbidity, quality-of-life impairment and health-care costs. Although many patients can be treated satisfactorily with topical medications and phototherapy, a smaller subset requires more aggressive systemic therapies. Multiple studies have shown promise for the use of mycophenolate mofetil (MMF) to treat refractory AD. This report summarizes the evidence for use of MMF in the treatment of recalcitrant AD for both children and adults. Familiarity with these studies on the benefits and risks of MMF will enable the clinician and patient to select the most appropriate therapy.<br /><br /> <em>J Drugs Dermatol</em>. 2016;15(6):715-718.
Lisa
L
Prussick
Natalia
N
Plotnikova
Alice
A
Gottlieb
D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000188:drug therapy*; D004791:Enzyme Inhibitors / Q000009:adverse effects / Q000627:therapeutic use*; D005767:Gastrointestinal Diseases / Q000139:chemically induced / Q000175:diagnosis; D006801:Humans; D009173:Mycophenolic Acid / Q000009:adverse effects / Q000627:therapeutic use*; D012720:Severity of Illness Index
D004791:Enzyme Inhibitors; D009173:Mycophenolic Acid