A Case Report of Local Recurrence Developing 24 Years After Mastectomy for Breast Cancer Recurrence From Breast Cancer After 24 Years.
BACKGROUND
Breast cancer is a commonly diagnosed cancer, in which most patients' metastases (about 75%) occurred in 5 years after the initial diagnosis, especially in 3 years. Recrudescence exceeding 20 years is rarely reported in the past several decades.Case information: A 68-year-old female patient presented with breast cancer in which 3 focal increased 18F-fluorodeoxyglucose uptake in the right supraclavicular lymph node, the mediastinum and sternum were found on positron emission tomography and computed tomography. Then we learned that the patient had suffered from breast cancer and been given a right-sided mastectomy 24 years ago. Histopathology from the mediastinum revealed metastatic, moderately differentiated breast adenomatous cell carcinoma.


CONCLUSIONS
We report this late recurrence of breast cancer 24 years following mastectomy, suggesting that possible recurrence of this disease with a 24-year latency period should be taken into consideration.
From the School of Medicine and Life Sciences (L-LX, HZ, Y-CW, QZ), University of Jinan-Shandong Academy of Medical Sciences; (L-LX, X-DH, S-ZW, Y-SG, QXY, SG, HZ, Y-CW, QZ, S-HY), Shandong cancer hospital affiliated to Shandong University, Jinan, Shandong, China; and (S-HY), Shandong Academy of Medical Sciences, Jinan, Shandong, China.
Linlin
L
Xiao
Xudong
X
Hu
Suzhen
S
Wang
Gao
G
Yong-Sheng
Qingxi
Q
Yu
Song
S
Gao
Hui
H
Zhang
Yuchun
Y
Wei
Qian
Q
Zhao
Shuang-Hu
SH
Yuan
D000368:Aged; D014408:Biomarkers, Tumor; D001943:Breast Neoplasms / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D005260:Female; D006801:Humans; D008207:Lymphatic Metastasis; D008408:Mastectomy / Q000379:methods*; D009364:Neoplasm Recurrence, Local; D018307:Neoplasms, Squamous Cell / Q000175:diagnosis / Q000473:pathology* / Q000601:surgery*; D013997:Time Factors
D014408:Biomarkers, Tumor