Renchangianins F and G: two new sesquiterpenoids from Kadsura renchangiana.
Phytochemical investigation on the stems of Kadsura renchangiana led to the isolation of two new sesquiterpenoids, renchangianins F and G (1 and 2). Their structures were elucidated by spectroscopic methods, including 2D NMR techniques. The in vitro cytotoxic activities of the isolates were studied against HepG2, A549, and LN229 cancer cell lines.
a Key Laboratory of Luminescent Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715 , China.
Li-Qing
LQ
Deng
a Key Laboratory of Luminescent Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715 , China.
Guo-Wei
GW
Wang
a Key Laboratory of Luminescent Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715 , China.
Si-Yu
SY
Zhou
a Key Laboratory of Luminescent Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715 , China.
Jing-Qiu
JQ
Ge
b School of Life Sciences , Southwest University , Chongqing 400715 , China.
Zhi-Hua
ZH
Liao
c Department of Pharmacognosy , School of Pharmacy, Fudan University , Shanghai 201203 , China.
Dao-Feng
DF
Chen
a Key Laboratory of Luminescent Real-Time Analytical Chemistry (Southwest University), Ministry of Education, College of Pharmaceutical Sciences, Southwest University, Chongqing 400715 , China.
Min
M
Chen
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D004354:Drug Screening Assays, Antitumor; D056945:Hep G2 Cells; D006801:Humans; D032135:Kadsura / Q000737:chemistry*; D015394:Molecular Structure; D019906:Nuclear Magnetic Resonance, Biomolecular; D018547:Plant Stems / Q000737:chemistry; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology
D000972:Antineoplastic Agents, Phytogenic; D012717:Sesquiterpenes; C000616018:renchangianin F; C000616019:renchangianin G
Kadsura renchangiana; Schisandraceae; cytotoxicity; renchangianin F; renchangianin G; sesquiterpenoids