Rare case of stress cardiomyopathy due to intramuscular epinephrine administration.
We report a case of a 37-year-old woman who presented to our hospital with retrosternal chest pain following intramuscular administration of epinephrine due to presumed anaphylaxis. On arrival, she was found to have ST segment depression in the anterolateral leads on ECG and elevated cardiac troponins. She was diagnosed with stress cardiomyopathy based on left ventricle dysfunction and angiographically normal coronary arteries on cardiac catheterisation. To the best of our knowledge, this is the third reported case of takotsubo cardiomyopathy following appropriately dosed intramuscular administration of epinephrine for anaphylaxis. This case highlights the importance of considering stress cardiomyopathy in patients presenting with chest pain syndrome following systemic administration of epinephrine.
Reading Hospital and Medical Center, Reading, Pennsylvania, USA.
Salik
S
Nazir
Reading Hospital and Medical Center, Reading, Pennsylvania, USA.
Stephen
S
Melnick
Reading Hospital and Medical Center, Reading, Pennsylvania, USA.
Saroj
S
Lohani
Reading Hospital and Medical Center, Reading, Pennsylvania, USA.
Benjamin
B
Lloyd
D000281:Administration, Intranasal; D000319:Adrenergic beta-Antagonists / Q000627:therapeutic use; D000328:Adult; D000707:Anaphylaxis / Q000188:drug therapy; D000806:Angiotensin-Converting Enzyme Inhibitors / Q000627:therapeutic use; D001241:Aspirin / Q000627:therapeutic use; D004452:Echocardiography; D004837:Epinephrine / Q000008:administration & dosage / Q000009:adverse effects*; D005260:Female; D006801:Humans; D035583:Rare Diseases / Q000139:chemically induced; D054549:Takotsubo Cardiomyopathy / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000188:drug therapy
D000319:Adrenergic beta-Antagonists; D000806:Angiotensin-Converting Enzyme Inhibitors; D001241:Aspirin; D004837:Epinephrine