Scleredema-associated IgA myeloma with myelofibrosis in a young adult: a case report.
Scleredema of Buschke is a rare fibromucinous connective tissue disorder of unknown etiology. It is often associated with a benign monoclonal gammopathy and rarely with myelomatosis. We report a case of scleredema-associated IgA myeloma with myelofibrosis in a 24-year-old male patient. Scleredema generally affects young adults and onset of associated monoclonal gammopathy is at a younger age than when not associated with scleredema. However, presentation at a much younger age (24 years in our case) is very unusual. Although mucin deposition in the bone marrow has been reported in scleredema, to the best of our knowledge, myelofibrosis has not been reported.
Seema
S
Rao
Rakhee
R
Kar
Hara Prasad
HP
Pati
Dept. Of Hematology,irch Building,all India Institute Of Medical Sciences,ansari Nagar, new Delhi-110029 11002 New Delhi-India, Phone: 91-011-26594670-91 E-mail: renusax@hotmail.com.
Renu
R
Saxena