Outcome and survival in canine sick sinus syndrome and sinus node dysfunction: 93 cases (2002-2014).
BACKGROUND
To evaluate the clinical presentation, diagnosis, treatment, and outcomes of a group of dogs with sinoatrial node abnormalities.


METHODS
Ninety-three client-owned dogs at a referral institution.


METHODS
Medical records were reviewed for clinical history, diagnostic testing, and medical or permanent artificial pacemaker (PAP) treatment. Owners or veterinarians were contacted for long-term follow-up.


RESULTS
Sixty-one dogs were symptomatic for their bradyarrhythmia and were diagnosed with sick sinus syndrome (SSS). Thirty-two dogs were asymptomatic for their bradyarrhythmia and were diagnosed with sinus node dysfunction (SND). Miniature Schnauzers, West Highland White terriers, Cocker spaniels, and female dogs were overrepresented. Medical management with positive chronotropic drugs successfully controlled syncope long-term in 54% of SSS dogs, and acted as a bridge to PAP in 20%. Positive atropine response predicted medical treatment success. Forty-six percent of SSS dogs eventually underwent PAP implantation. Median survival time was approximately 18 months in SND and SSS dogs regardless of treatment strategy. Congestive heart failure (CHF) associated with progressive valvular heart disease occurred commonly in all groups, particularly in dogs with bradycardia-tachycardia syndrome.


CONCLUSIONS
Sinus node dysfunction and SSS represent a spectrum of sinoatrial node disease, which for some dogs may also involve a component of autonomic dysfunction. Dogs with SND do not require treatment. Dogs with SSS often require treatment to reduce the frequency of syncope; medical management is often useful, particularly in atropine responsive dogs. Prognosis of SSS with treatment is good, though development of CHF does not appear to be mitigated by treatment.
North Carolina State University Veterinary Hospital, 1052 William Moore Dr, Raleigh, NC 27607, USA.
J L
JL
Ward
North Carolina State University Veterinary Hospital, 1052 William Moore Dr, Raleigh, NC 27607, USA.
T C
TC
DeFrancesco
North Carolina State University Veterinary Hospital, 1052 William Moore Dr, Raleigh, NC 27607, USA.
S P
SP
Tou
North Carolina State University Veterinary Hospital, 1052 William Moore Dr, Raleigh, NC 27607, USA.
C E
CE
Atkins
North Carolina State University Veterinary Hospital, 1052 William Moore Dr, Raleigh, NC 27607, USA.
E H
EH
Griffith
North Carolina State University Veterinary Hospital, 1052 William Moore Dr, Raleigh, NC 27607, USA. Electronic address: bwkeene@ncsu.edu.
B W
BW
Keene
D000818:Animals; D004283:Dog Diseases / Q000401:mortality*; D004285:Dogs; D011379:Prognosis; D012804:Sick Sinus Syndrome / Q000401:mortality / Q000662:veterinary*; D012849:Sinoatrial Node / Q000503:physiopathology*; D016019:Survival Analysis; D016896:Treatment Outcome
Arrhythmia; Bradycardia; Dog; Pacemaker; Sinus arrest