Ni-Catalyzed Amination Reactions: An Overview.
Nitrogen-containing organic compounds are valuable in many fields of science and industry. The most reliable method for the construction of C(sp(2) )-N bonds is undoubtedly palladium-catalyzed amination. In spite of the great achievements made in this area, the use of expensive Pd-based catalysts constitutes an important limitation for large-scale applications. Since nickel is the least expensive and most abundant among the group 10 metals, the interest in Ni-based catalysts for processes typically catalyzed by palladium has grown considerably over the last few years. Herein, we revise the development of Ni-catalyzed amination reactions, emphasizing the most relevant and recent advances in the field.
Departamento de Química Inorgánica, Universidad de Sevilla, Aptdo 1203, 41071, Sevilla, Spain.
Mario
M
Marín
Departamento de Química Inorgánica, Universidad de Sevilla, Aptdo 1203, 41071, Sevilla, Spain.
Raquel J
RJ
Rama
Departamento de Química Inorgánica, Universidad de Sevilla, Aptdo 1203, 41071, Sevilla, Spain.
M Carmen
MC
Nicasio
N-aryl amines; amination; cross-coupling; nickel catalysis