Leiomyomatosis Peritonealis Disseminata (LPD) ten years after laparoscopic myomectomy associated with ascites and lymph nodes enlargement: a case report.
BACKGROUND
We report a case of leiomyomatosis peritonealis disseminata (LPD) arising 10 years after a laparoscopic myomectomy that was associated with ascites and lymph nodes enlargement.


METHODS
The patient presented with small uterine fibroids with a dominant posterior intramural fibroid measuring 9cm in diameter and normal Doppler. Laparotomy revealed a uterus enlarged with fibroids, which was densely adhering to the urinary bladder, greater omentum, and sigmoid colon. Multiple tumors of different size were found attached to the peritoneum, omentum and bowel. The histopathologic examination was consistent with leiomyomatosis peritonealis disseminata.


CONCLUSIONS
Pieces of smooth muscle cell lost in the abdominal cavity during electrical morcellation after laparoscopic myomectomy may progress to leiomyomatosis peritonealis disseminata even after many years (ten in our case) and it can be associated with ascites and lymph nodes enlargement.


CONCLUSIONS
This is the first case reported in literature of leiomyomatosis peritonealis disseminata with these particular features (time of clinical presentation, ascites, lymph nodes enlargement).
Institute of Obstetrics and Gynaecology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Luigi
L
Nappi
Institute of Obstetrics and Gynaecology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy. Electronic address: felice.sorrentino@alice.it.
Felice
F
Sorrentino
Institute of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Stefano
S
Angioni
Institute of Obstetrics and Gynaecology, Department of Surgical Sciences, University of Cagliari, Cagliari, Italy.
Alessandro
A
Pontis
Institute of Obstetrics and Gynaecology, Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy.
Ida
I
Barone
Department of Morphology, Surgery and Experimental Medicine, Section of Obstetrics and Gynaecology, University of Ferrara, Ferrara, Italy.
Pantaleo
P
Greco
Ascites; Electrical morcellation; Leiomyomatosis peritonealis disseminata; Myomectomy