Spontaneous dissection of the arterial duct during continuous infusion of prostaglandin E1 in a neonate with aortic arch interruption.
We report a 3-day-old boy with double outlet of the right ventricle and interruption of the aortic arch who developed spontaneous dissection of the arterial duct (DA) despite use of continuous infusion of lipo-prostaglandin E1 (PGE1). Transthoracic echocardiography demonstrated the spontaneous dissecting aneurysm of DA, which was confirmed by histology at the modified Norwood procedure done at age of 18 days. This is the first report of spontaneous dissection of DA in a neonate receiving PGE1, suggesting a new closing mechanism of DA.
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Nao
N
Inoue
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan. syasukochi@naganoch.gr.jp.
Satoshi
S
Yasukochi
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Kiyohiro
K
Takigiku
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Hikoro
H
Matsui
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Kohta
K
Takei
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Yusuke
Y
Nakano
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Tessyu
T
Otagiri
Department of Pediatric Cardiology, Nagano Children's Hospital, 3100 Toyoshina, Azumino, Nagano, 399-8288, Japan.
Yuichiro
Y
Hashida
Department of Pathology, Nagano Children's Hospital, Azumino, Japan.
Yoshifumi
Y
Ogiso
Department of Cardiothoracic Surgery, Nagano Children's Hospital, Azumino, Japan.
Yoshiyuki
Y
Maekawa
Department of Cardiothoracic Surgery, Nagano Children's Hospital, Azumino, Japan.
Kentaro
K
Umezu
Department of Cardiothoracic Surgery, Nagano Children's Hospital, Azumino, Japan.
Takahiko
T
Sakamoto
Department of Cardiothoracic Surgery, Nagano Children's Hospital, Azumino, Japan.
Yorikazu
Y
Harada
Bilateral pulmonary arterial banding; Congenital heart disease; Dissection of the arterial duct; Prostaglandin E1