Synthesis of 6-phosphofructose aspartic acid and some related Amadori compounds.
We describe the synthesis and characterization of 6-phosphofructose-aspartic acid, an intermediate in the metabolism of fructose-asparagine by Salmonella. We also report improved syntheses of fructose-asparagine itself and of fructose-aspartic acid.
Campus Chemical Instrument Center, The Ohio State University, 496 W. 12th Avenue, Columbus, OH 43210, USA. Electronic address: Hansen.434@osu.edu.
Alexandar L
AL
Hansen
Department of Chemistry & Biochemistry, The Ohio State University, 484 W. 12th Avenue, Columbus, OH 43210, USA. Electronic address: Behrman.1@osu.edu.
Edward J
EJ
Behrman
D001216:Asparagine / Q000737:chemistry; D001224:Aspartic Acid / Q000031:analogs & derivatives* / Q000737:chemistry; D005636:Fructosephosphates / Q000138:chemical synthesis* / Q000737:chemistry; D015394:Molecular Structure
D005636:Fructosephosphates; D001224:Aspartic Acid; D001216:Asparagine
6-Phosphofructose-aspartic acid; Amadori rearrangement; Fructose-asparagine; Fructose-aspartic acid; Salmonella