Studies on regeneration of central nervous system and social ability of the earthworm Eudrilus eugeniae.
Earthworms are segmented invertebrates that belong to the phylum Annelida. The segments can be divided into the anterior, clitellar and posterior parts. If the anterior part of the earthworm, which includes the brain, is amputated, the worm would essentially survive even in the absence of the brain. In these brain amputee-derived worms, the nerve cord serves as the primary control center for neurological function. In this current work, we studied changes in the expression levels of anti-acetylated tubulin and serotonin as the indicators of neuro-regenerative processes. The data reveal that the blastemal tissues express the acetylated tubulin and serotonin from day four and that the worm amputated at the 7th segment takes 30 days to complete the regeneration of brain. The ability of self-assemblage is one of the specific functions of the earthworm's brain. The brain amputee restored the ability of self-assemblage on the eighth day.
Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Nino
N
Gopi Daisy
Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Elaiya Raja
ER
Subramanian
Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Jackson Durairaj
JD
Selvan Christyraj
Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Dinesh Kumar
DK
Sudalai Mani
Center for Nanoscience and Nanotechnology, Molecular Nanomedicine Research Unit, Sathyabama University, Chennai, Tamilnadu, 600119, India.
Johnson Retnaraj Samuel
JR
Selvan Christyraj
Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India.
Kalidas
K
Ramamoorthy
Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.|Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Vaithilingaraja
V
Arumugaswami
Department of Biotechnology, Manonmaniam Sundaranar University, Tirunelveli, Tamilnadu, 627012, India. sudhakarmsu@yahoo.com.
Sudhakar
S
Sivasubramaniam
D000818:Animals; D002490:Central Nervous System / Q000502:physiology*; D009835:Oligochaeta / Q000502:physiology*; D012038:Regeneration / Q000502:physiology*; D012919:Social Behavior
Brain; Eudrilus eugeniae; Regeneration; Self-assemblage; Serotonin; Social behavior