Subcutaneous rhabdomyosarcoma in an old rabbit.
An 11-year-old castrated male rabbit presented with a subcutaneous mass in the right hind limb. The mass comprised solid and myxoid areas. Solid areas were characterized by a storiform or interlacing pattern of spindle cells, strap cells, multinucleated giant cells and round cells with eccentrically located nuclei, whereas the myxoid areas were composed predominantly of elongated fusiform cells with hyperchromatic nuclei embedded in Alcian Blue-positive myxoid stroma. Immunohistochemically, tumor cells in both areas were positive for desmin and vimentin. Ultrastructurally, the tumor cells in the solid areas had abundant myofilaments with electron dense Z-band structures. Based on these pathological findings, this case was diagnosed as rhabdomyosarcoma in a rabbit.
Department of Veterinary Pathology, School of Veterinary Medicine, Kitasato University, 23-35-1, Higashi, Towada, Aomori 034-8628, Japan.
Chun-Ho
CH
Park
Chikage
C
Nakajima
Kazunori
K
Kimitsuki
Nozomi
N
Shiwa
Yasuhiko
Y
Tsuchida
Hassadin
H
Boonsriroj
D000818:Animals; D008297:Male; D019042:Muscle Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D018482:Muscle, Skeletal / Q000473:pathology; D011817:Rabbits / Q000033:anatomy & histology*; D012208:Rhabdomyosarcoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*