Epidemiology of Clostridium difficile infection in hospitalized oncology patients.
The epidemiology of Clostridium difficile infection (CDI) among oncology inpatients is poorly understood. In multivariate analysis we identified age, history of CDI, and prior receipt of cephalosporins, β-lactam/β-lactamase inhibitors, metronidazole, and blood transfusion as risk factors associated with CDI. Reducing broad-spectrum antibiotic use, particularly among older patients and those with a CDI history and recent blood transfusions, may decrease CDI risk in this population.
Yale School of Public Health, New Haven, CT; Albert Einstein College of Medicine, Bronx, NY.
Gina Y
GY
Chang
Yale School of Public Health, New Haven, CT; Yale School of Medicine, New Haven, CT.
Louise M
LM
Dembry
Yale School of Public Health, New Haven, CT; Yale School of Medicine, New Haven, CT; University of Connecticut School of Medicine, Farmington, CT. Electronic address: dbanach@uchc.edu.
David B
DB
Banach
D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D016022:Case-Control Studies; D016360:Clostridioides difficile / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000453:epidemiology* / Q000382:microbiology; D005260:Female; D006760:Hospitalization; D006801:Humans; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000150:complications*; D012307:Risk Factors
Clostridium difficile; epidemiology; oncology