The Most Interesting Enzyme in the World.
Ribonucleotide reductases of the class I family are α2β2 tetramers. Like all RNRs they are subject to allosteric control mechanisms affecting activity and specificity. In this issue of Structure, Johansson et al. (2016) present a structural analysis of an unusual mode of activity site regulation.
Department of Biochemistry and Biophysics, Oregon State University, Corvallis, OR 97331, USA. Electronic address: mathewsc@oregonstate.edu.
Christopher K
CK
Mathews
D000494:Allosteric Regulation; D020134:Catalytic Domain; D010084:Oxidation-Reduction; D012264:Ribonucleotide Reductases / Q000737:chemistry*
D012264:Ribonucleotide Reductases