High wholegrain barley β-glucan lowers food intake but does not alter small intestinal macronutrient digestibility in ileorectostomised rats.
Using barley cultivars differing widely in β-glucan content, we aimed to determine their effects on small intestinal macronutrient digestion in 24 ileorectostomised rats. The rats were fed 1 of 4 experimental diets, each containing a different barley variety, for 11 d. The diets had a content of 0, 2.1, 2.6 and 4.3 g of β-glucan/100 g. Feed intake and faecal excretion of fat, protein, starch, and non-starch polysaccharides were determined in the final 5 d of the study and apparent macronutrient digestibility calculated. Higher dietary levels of β-glucan (2.6% and 4.3%) lowered feed intake (by 15 and 19%, respectively) but final body weight was only lowered by the 4.3% β-glucan diet relative to rats fed the 0% β-glucan diet (all ps < 0.05). Protein, lipid and starch digestibility was unrelated to the dietary β-glucan content. Higher dietary levels of barley β-glucan lower feed intake of ileorectostomised rats, which is independent of intestinal fermentation and unrelated to macronutrient digestibility.
a CSIRO Food and Nutrition , Adelaide , SA , Australia ;
Damien P
DP
Belobrajdic
b Department of Applied Biological Chemistry, Faculty of Agriculture , Shizuoka University , Shizuoka , Japan ;
Shingo
S
Hino
b Department of Applied Biological Chemistry, Faculty of Agriculture , Shizuoka University , Shizuoka , Japan ;
Takashi
T
Kondo
c CSIRO Agriculture , Black Mountain , ACT , Australia.
Stephen A
SA
Jobling
c CSIRO Agriculture , Black Mountain , ACT , Australia.
Matthew K
MK
Morell
a CSIRO Food and Nutrition , Adelaide , SA , Australia ;
David L
DL
Topping
b Department of Applied Biological Chemistry, Faculty of Agriculture , Shizuoka University , Shizuoka , Japan ;
Tatsuya
T
Morita
a CSIRO Food and Nutrition , Adelaide , SA , Australia ;
Anthony R
AR
Bird
D000818:Animals; D004032:Diet; D004041:Dietary Fats / Q000008:administration & dosage / Q000032:analysis; D004044:Dietary Proteins / Q000008:administration & dosage / Q000032:analysis; D004063:Digestion; D005243:Feces / Q000737:chemistry; D005285:Fermentation; D001467:Hordeum / Q000737:chemistry*; D007081:Ileostomy; D007421:Intestine, Small / Q000378:metabolism*; D008297:Male; D011134:Polysaccharides / Q000008:administration & dosage / Q000032:analysis; D051381:Rats; D017207:Rats, Sprague-Dawley; D013213:Starch / Q000008:administration & dosage / Q000032:analysis; D000067348:Whole Grains / Q000737:chemistry*; D047071:beta-Glucans / Q000008:administration & dosage / Q000032:analysis*
D004041:Dietary Fats; D004044:Dietary Proteins; D011134:Polysaccharides; D047071:beta-Glucans; D013213:Starch
Barley; beta-glucan; fat; fibre; ileorectostomy; macronutrient digestibility; protein; rat; satiety; starch; wholegrain