Ultrasonography Significantly Overestimates Stone Size When Compared to Low-dose, Noncontrast Computed Tomography.
OBJECTIVE
To evaluate the differences between low-dose noncontrast computed tomography (NCCT) and renal ultrasound (US) in the identification and measurement of urinary calculi.


METHODS
A retrospective review was conducted at 3 institutions of patients evaluated for flank pain with both renal US and NCCT, within 1 day of one another, from 2012 to 2015. Stone presence and size were compared between imaging modalities. Stone size was determined by largest measured diameter. Stones were grouped into size categories (≤5 mm, 5.1-10 mm, and >10 mm) based on NCCT and compared with US. Statistical analysis was performed using 2-sided t tests.


RESULTS
One hundred fifty-five patients received both a renal US and NCCT within 1 day. In 79 patients (51.0%), both US and NCCT identified a stone for size comparison. Fifty-eight patients (37.4%) had a stone visualized on NCCT but not on US, and 2 patients (1.3%) had a stone documented on US but not seen on NCCT. The average NCCT size of the stones missed on US was 4.5 mm. When comparing the average largest stone diameter for US (9.1 mm) vs NCCT (6.9 mm), US overestimated stone size by 2.2 mm (P < .001). US overestimated stone size by 84.6% for stones ≤5 mm, 27.1% for stones 5.1-10 mm, and 3.0% for stones >10 mm.


CONCLUSIONS
US significantly overestimated stone size and this was most pronounced for small (≤5 mm) stones. The potential for systematic overestimation of stone size with standard US techniques should be taken into consideration when evaluating endourologic treatment options.
Division of Urology, University of Vermont Medical Center, Burlington, VT. Electronic address: kevan.sternberg@uvmhealth.org.
Kevan M
KM
Sternberg
Department of Urology, Harvard Medical School, Massachusetts General Hospital, Boston, MA.
Brian
B
Eisner
University of Vermont Medical Center, Burlington, VT.
Troy
T
Larson
Department of Urology, Harvard Medical School, Massachusetts General Hospital, Boston, MA.
Natalia
N
Hernandez
Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Jullet
J
Han
Section of Urology, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Vernon M
VM
Pais
D000328:Adult; D003287:Contrast Media; D061827:Dimensional Measurement Accuracy; D005260:Female; D006801:Humans; D008297:Male; D011829:Radiation Dosage; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed / Q000379:methods; D014463:Ultrasonography; D014545:Urinary Calculi / Q000000981:diagnostic imaging* / Q000473:pathology*
D003287:Contrast Media