Mother and Child: Medication Use in Pregnancy and Lactation.
Pregnancy and breastfeeding pose a unique challenge to drug development and clinical application. In addition to drug toxicity to the fetus in utero and infants through breastfeeding, alterations of pharmacokinetics in those women also need careful attention. How do we turn around the overall lack of drug efficacy and toxicity information for pregnant and breastfeeding women?
Division of Clinical Pharmacology and Toxicology, Department of Paediatrics, Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.
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D000014:Abnormalities, Drug-Induced / Q000517:prevention & control*; D001942:Breast Feeding; D015195:Drug Design; D005260:Female; D005333:Fetus / Q000187:drug effects; D006801:Humans; D007223:Infant; D007774:Lactation; D004364:Pharmaceutical Preparations / Q000008:administration & dosage / Q000378:metabolism; D010599:Pharmacokinetics; D011247:Pregnancy; D011248:Pregnancy Complications / Q000188:drug therapy*
D004364:Pharmaceutical Preparations