Secular trends in the prevalence of type 2 diabetes in adults in China from 1995 to 2014: A meta-analysis.
BACKGROUND
The aim of the present study was to estimate trends in the prevalence of type 2 diabetes mellitus (T2DM) in adults in China.


METHODS
A systematic search was conducted for studies of T2DM prevalence in adults in China from 2000 to 2014. Pooled prevalence was calculated by a random-effects model. Subgroup and sensitivity analyses were performed. Chi-squared and Cochran-Mantel-Haenszel tests were used to assess differences among subgroups and pooled prevalence, respectively.


RESULTS
Forty-six studies (data from 1995 to 2014; 1 463 079 adults) were included in the meta-analysis. The overall prevalence of T2DM was 7.9 %. The pooled prevalence overall and by location (urban and rural), gender (male and female), and age category (18-39, 40-59, and ≥60 years) was 4.5 %, 5.1 % and 3.0 %, 4.0 % and 4.2 %, and 1.4 %, 5.0 %, and 10.3 %, respectively, from 1995 to 1999; 6.6 %, 9.3 % and 5.6 %, 7.4 % and 7.5 %, and 1.8 %, 5.9 %, and 12.4 %, respectively, from 2000 to 2004; 10.3 %, 11.8 % and 6.8 %, 10.0 % and 8.6 %, and 2.8 %, 10.3 %, and 20.0 %, respectively, from 2005 to 2009; and 8.3 %, 12.5 % and 7.6 %, 8.6 % and 8.0 %, and 3.5 %, 8.5 %, and 15.3 %, respectively, from 2010 to 2014. The prevalence increased from 5.8 % to 11.6 % with per-capita gross domestic product and differed by diagnostic criteria.


CONCLUSIONS
There was a trend of increasing prevalence of T2DM in adults in China from 1995 to 2009, with a decrease in 2010-14 and a greater increase over time in urban versus rural areas, males versus females, and older versus younger adults.
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.|Department of Prevention and Health Care, The Affiliated Luohu Hospital of Shenzhen University Health Sciences Center, Shenzhen, China.|Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Chengyi
C
Han
Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Ming
M
Zhang
Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Xinping
X
Luo
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Chongjian
C
Wang
Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, China.
Lei
L
Yin
Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, China.
Chao
C
Pang
Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, China.
Tianping
T
Feng
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.|Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Yongcheng
Y
Ren
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.|Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Bingyuan
B
Wang
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Lu
L
Zhang
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Linlin
L
Li
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Xiangyu
X
Yang
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Hongyan
H
Zhang
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.
Yang
Y
Zhao
Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Junmei
J
Zhou
Intensive Care Unit, Zhoukou City Central Hospital, Zhoukou, China.
Zhihui
Z
Xie
Department of Prevention and Health Care, Military Hospital of Henan Province, Zhengzhou, China.
Jingzhi
J
Zhao
Department of Epidemiology and Health Statistics, College of Public Health, Zhengzhou University, Zhengzhou, China.|Department of Prevention and Health Care, The Affiliated Luohu Hospital of Shenzhen University Health Sciences Center, Shenzhen, China.|Department of Preventive Medicine, Shenzhen University Health Sciences Center, Shenzhen, China.
Dongsheng
D
Hu
D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D016009:Chi-Square Distribution; D002681:China / Q000453:epidemiology; D003924:Diabetes Mellitus, Type 2 / Q000175:diagnosis* / Q000453:epidemiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D012423:Rural Health / Q000706:statistics & numerical data* / Q000639:trends; D012737:Sex Factors; D014504:Urban Health / Q000706:statistics & numerical data* / Q000639:trends; D055815:Young Adult
2型糖尿病; meta-analysis; meta分析; prevalence; type 2 diabetes; 患病率