Changes in visual field defects during 10-year follow-up for indocyanine green-assisted macular hole surgery.
OBJECTIVE
To determine whether the visual field defects detected within 3 months of indocyanine green (ICG)-assisted inner-limiting membrane (ILM) peeling continue to worsen over longer periods.


METHODS
This was a retrospective observational case series. Four eyes with visual field defects that developed within 3 years of ICG-assisted ILM peeling for a macular hole (MH) were examined yearly for 10 years. The main outcome measures were the degree of mean deviation (MD) determined by Humphrey perimetry with the 30-2 SITA-Fast program and the best-corrected visual acuity (BCVA).


RESULTS
Four patients were examined yearly for more than 10 years, with a mean duration of follow-up of 139.5 months (11.6 years) and a range of follow-up of 137-156 months (11.4-13 years). The mean (±standard deviation) preoperative MD value was -4.99 ± 3.26 dB, and the mean postoperative MD values were -12.9 ± 1.29 dB after 1 year, -14.1 ± 0.75 dB after 3 years, and -12.73 ± 2.65 dB after 10 years. The mean preoperative BCVA was 0.65 ± 0.26 logarithm of the minimal angle of resolution (logMAR) units, and the postoperative BCVA was 0.21 ± 0.07 logMAR units at 1 year, 0.28 ± 0.21 logMAR units at 3 years, and 0.14 ± 0.06 dB logMAR units at 10 years.


CONCLUSIONS
The visual field defects detected soon after ICG-assisted ILM peeling continued to worsen for 3 years, but not thereafter.
Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Masanori
M
Nakazawa
Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Hiroto
H
Terasaki
Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Takehiro
T
Yamashita
Department of Ophthalmology, Kagoshima City Hospital, Kagoshima, Japan.
Akinori
A
Uemura
Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan. tsakamot@m3.kufm.kagoshima-u.ac.jp.
Taiji
T
Sakamoto
D000368:Aged; D004396:Coloring Agents / Q000494:pharmacology; D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D006801:Humans; D007208:Indocyanine Green / Q000494:pharmacology*; D008297:Male; D008875:Middle Aged; D012167:Retinal Perforations / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D012189:Retrospective Studies; D012607:Scotoma / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology*; D025321:Surgery, Computer-Assisted / Q000379:methods*; D014794:Visual Fields / Q000502:physiology*
D004396:Coloring Agents; D007208:Indocyanine Green
ILM peeling; Indocyanine green; Macular hole; Visual field defect