Trend of invasive pneumococal disease (IPD) in a South Western, Nigerian hospital.
The recent introduction of the Heptavalent-pneumococcal vaccine (PCV-7) by private pharmaceutical companies in Nigeria, has generated interest in invasive bacterial diseases particularly IPD. Our objective in this study is to investigate the trend and occurrence rate of IPD in Abeokuta, Nigeria. Suspected IPD cases were assessed from Jan 2010 to Dec 2010 for demographic and Microbiological characteristics. Bacterial isolations and antibiotics susceptibility testing followed standard bacteriological procedure. Overall 471 cases of probable IPD was assessed, with 21(4.5%) cases of suspected pneumonia, 109(23.1%) cases of suspected meningitis, and 341(72.4%) cases of suspected septicaemia. Confirmed IPD cases were 9 with 2 cases of meningitis, 3 cases of septicaemia and 4 cases of pneumonia. Age range distribution showed, high distribution of IPD cases among children >1 with 5(55.6%) there was a statistically significant difference in gender p< 0.05 (X2 test) with females recording a higher occurrence than males. We conclude by advocating for better detection methods against IPD meningitis cases, and continuous surveillance into the serotypes of streptococcus pneumonia as well inclusion of the PCV vaccine into our childhood immunization program.
Medical Microbiology Unit, Pathology Department, Federal Medical Centre, Abeokuta, Nigeria.
Motayo Babatunde
MB
Olanrewaju
Medical Microbiology Unit, Pathology Department, Federal Medical Centre, Abeokuta, Nigeria.
Akingbade
A
Olusola
Medical Microbiology Unit, Pathology Department, Federal Medical Centre, Abeokuta, Nigeria.
Nwadike
N
Victor
Department of Microbiology, Federal University of Agriculture, Abeokuta, Nigeria.
Shobayo
S
Olabode
Medical Microbiology Unit, Pathology Department, Federal Medical Centre, Abeokuta, Nigeria.
Ogiogwa
O
Joseph
Department of Vetenary Microbiology and Parasitology, Federal University of Agriculture, Abeokuta,Nigeria.
Akinduti
A
Akiniyi
Department of Microbiology, University of Port-Harcort, Nigeria.
Okonko
O
Iheanyi
D000293:Adolescent; D017677:Age Distribution; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D005260:Female; D000069443:Heptavalent Pneumococcal Conjugate Vaccine / Q000008:administration & dosage; D006801:Humans; D007223:Infant; D008297:Male; D008586:Meningitis, Pneumococcal / Q000453:epidemiology* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D009549:Nigeria / Q000453:epidemiology; D011008:Pneumococcal Infections / Q000453:epidemiology*; D011018:Pneumonia, Pneumococcal / Q000453:epidemiology* / Q000382:microbiology; D018805:Sepsis / Q000453:epidemiology* / Q000382:microbiology; D017678:Sex Distribution; D013296:Streptococcus pneumoniae / Q000187:drug effects / Q000302:isolation & purification
D000900:Anti-Bacterial Agents; D000069443:Heptavalent Pneumococcal Conjugate Vaccine
Abeokuta; IPD; Immunization; streptococcus pneumonia