DNA hydrogel microspheres and their potential applications for protein delivery and live cell monitoring.
Microfluidic devices have been extensively developed as methods for microscale materials fabrication. It has also been adopted for polymeric microsphere fabrication and in situ drug encapsulation. Here, we employed multi-inlet microfluidic channels for DNA hydrogel microsphere formation and in situ protein encapsulation. The release of encapsulated proteins from DNA hydrogels showed different profiles accordingly with the size of microspheres.
Department of Chemistry, Myongji University , 116 Myongji-Ro, Cheoin-Gu, Yongin, Gyeonggi-Do 449-728, South Korea.
Taeyoung
T
Kim
Department of Chemistry, Myongji University , 116 Myongji-Ro, Cheoin-Gu, Yongin, Gyeonggi-Do 449-728, South Korea.
Seongmin
S
Park
Department of Chemistry, Myongji University , 116 Myongji-Ro, Cheoin-Gu, Yongin, Gyeonggi-Do 449-728, South Korea.
Minhyuk
0000-0002-3297-9386
M
Lee
Department of Chemistry, Myongji University , 116 Myongji-Ro, Cheoin-Gu, Yongin, Gyeonggi-Do 449-728, South Korea.
Solhee
S
Baek
Department of Chemical Engineering, University of Seoul , Seoul 130-743, South Korea.
Jong Bum
JB
Lee
Department of Chemistry, Myongji University , 116 Myongji-Ro, Cheoin-Gu, Yongin, Gyeonggi-Do 449-728, South Korea.
Nokyoung
N
Park