The effects of dietary nitrate supplementation on the adaptations to sprint interval training in previously untrained males.
OBJECTIVE
Dietary nitrate can improve repeated high-intensity and supramaximal exercise performance, although the effect on adaptations to training has received limited attention. The purpose of this study was to investigate the effects of dietary nitrate on the response to 3-weeks of sprint interval training (SIT).


METHODS
Randomized control trial.


METHODS
Twenty-seven untrained males (Age: 28±7 y, V⋅O2Max: 42±7mlkg-1min-1) completed an incremental exercise test at the beginning and end of the study. Participants were matched for V⋅O2Maxand randomly assigned to a control group (CON; n=8), SIT+placebo group (PLA; n=10), or SIT+nitrate group (NIT; n=9). The SIT comprised 4-6 repeated 15 s all out sprints on a cycle ergometer, interspersed with 4min active recovery, 3-times per week. Approximately 2.5h prior to exercise, participants consumed gels containing ∼0.1mmol (PLA) or ∼8mmol nitrate (NIT).


RESULTS
Following SIT, V⋅O2Max(PLA: 5%, p=0.057, d=0.34; NIT: 6.3%, p=0.041, d=0.34) and ventilatory threshold (VT) increased to a similar extent in both SIT groups. Maximum work rate tended to increase to a greater extent in NIT (8.7%, d=0.55) compared to PLA (4.7%, d=0.31, p=0.073). Fatigue index, calculated by the change in mean power from the first to the last sprint, tended to be reduced following SIT in NIT compared to PLA (PLA: 7.3±7.4%, NIT: 0.5±7.1%, p=0.058).


CONCLUSIONS
While dietary nitrate supplementation does not augment improvements to V⋅O2Maxand VT following SIT, it may improve WRmaxand indices of repeated high-intensity exercise.
Institute for Clinical Exercise and Health Science, University of the West of Scotland, UK.
David J
DJ
Muggeridge
Institute for Clinical Exercise and Health Science, University of the West of Scotland, UK.
Nicholas
N
Sculthorpe
Wales Heart Research Institute, Cardiff University Medical School, UK.
Philip E
PE
James
Institute for Clinical Exercise and Health Science, University of the West of Scotland, UK. Electronic address: chris.easton@uws.ac.uk.
Chris
C
Easton
D000222:Adaptation, Physiological; D000328:Adult; D019587:Dietary Supplements; D005080:Exercise Test / Q000187:drug effects*; D000072696:High-Intensity Interval Training / Q000379:methods*; D006801:Humans; D008297:Male; D018763:Muscle Fatigue / Q000502:physiology*; D009566:Nitrates / Q000008:administration & dosage*; D010101:Oxygen Consumption / Q000502:physiology; D055815:Young Adult
D009566:Nitrates
Exercise; Nitric oxide; Nitrite