Prevalence and Associated Factors of Erectile Dysfunction in Patients With Moderate to Severe Psoriasis and Healthy Population: A Comparative Study Considering Physical and Psychological Factors.
Recent studies have shown that psoriasis is associated with an increased prevalence of erectile dysfunction. To our knowledge, no comparative study has considered simultaneously the role of organic factors and psychological factors in this process. We performed a prospective case series study matched by age to explore the prevalence of erectile dysfunction in psoriasis patients compared to a healthy population and to investigate the role of anxiety, depression, and cardiovascular risk factors in the relationship between psoriasis and erectile dysfunction. The healthy group was matched by frequency to cases by age. Seventy-nine patients with moderate to severe psoriasis and 79 healthy controls participated in the study. Participants completed the Massachusetts General Hospital Sexual Functioning Questionnaire and the Hospital Anxiety and Depression Scale. Psoriasis patients had an increased prevalence of erectile dysfunction in comparison to controls, 34.2 vs. 17.7 % (p < .05). Multivariate analysis showed a significant association between erectile dysfunction and age, smoking and anxiety/depression, but not with psoriasis per se. In conclusion, the higher prevalence of smoking and anxiety/depression among patients with moderate to severe psoriasis probably explains the higher prevalence of erectile dysfunction in this population.
Department of Dermatology, Complejo Hospitalario Torrecárdenas, Almeria, Spain. alejandromolinaleyva@gmail.com.|Department of Dermatology, Complejo Hospitalario Universitario Granada, Avenida Doctor Oloriz 16, 18012, Granada, Spain. alejandromolinaleyva@gmail.com.
Alejandro
A
Molina-Leyva
Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.
Ignacio
I
Molina-Leyva
Department of Dermatology, Hospital Santa Ana, Granada, Spain.
Ana
A
Almodovar-Real
Department of Dermatology, Complejo Hospitalario Universitario Granada, Avenida Doctor Oloriz 16, 18012, Granada, Spain.
Jose Carlos
JC
Ruiz-Carrascosa
Department of Dermatology, Complejo Hospitalario Universitario Granada, Avenida Doctor Oloriz 16, 18012, Granada, Spain.
Ramon
R
Naranjo-Sintes
Department of Preventive Medicine and Public Health, University of Granada, Granada, Spain.|CIBER de Epidemiología y Salud Pública, Madrid, Spain.
Jose Juan
JJ
Jimenez-Moleon
D000328:Adult; D001007:Anxiety; D002318:Cardiovascular Diseases / Q000150:complications; D003863:Depression; D007172:Erectile Dysfunction / Q000150:complications / Q000453:epidemiology* / Q000523:psychology; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D015995:Prevalence; D011446:Prospective Studies; D011565:Psoriasis / Q000150:complications* / Q000523:psychology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects
Anxiety; Depression; Erectile dysfunction; Organic/medical factors; Psoriasis; Psychological factors