Associations of Psychometric Affective Parameters with Urodynamic Investigation for Urinary Frequency.
OBJECTIVE
To assess an association between affective symptoms and conventional urodynamic results in a pilot study.


METHODS
The study represents a retrospective analysis of prospectively obtained clinical data, voiding diaries, urodynamic parameters and Hospital Anxiety and Depression Scale (HADS).


RESULTS
A total of 74 patients with urinary frequency attending a multidisciplinary pelvic care centre was included in this study. There was a significant association between the total HADS scores and presence of DO (P = 0.019). In addition, results showed an association between HADS anxiety scores (≥8) and Detrusor Overactivity (DO) (P = 0.018) and between HADS depression scores (≥8) and the feeling of urgency (P = 0.028). Comparative analysis showed differences in age, mean voiding volume, bladder capacity and strong desire between patients with DO and those without.


CONCLUSIONS
This pilot study revealed an association between psychometric parameters and urodynamic results indicating a common pathway of bladder function and affective complaints. Further research is needed to elucidate which parts of the bladder-brain axis are involved and how these parts correspond by means of urodynamics.
Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands.|Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Desiree M J
DMJ
Vrijens
Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands.|Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Jamie M A F L
JMAFL
Drossaerts
Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Kevin
K
Rademakers
Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands.
Martijn
M
Smits
Division of Urology, Laboratory of Translational Neurosciences, University of Antwerp, Antwerp, Belgium.
Stefan G
SG
DE Wachter
Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.|Department of Psychiatry, Maastricht University Medical Centre, Maastricht, The Netherlands.
Carsten
C
Leue
Department of Urology, Maastricht University Medical Centre, Maastricht, The Netherlands.|Pelvic Care Centre Maastricht, Maastricht University Medical Centre, Maastricht, The Netherlands.
Gommert A
GA
VAN Koeveringe
D000342:Affective Symptoms / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008297:Male; D008499:Medical Records; D008875:Middle Aged; D010865:Pilot Projects; D011446:Prospective Studies; D011594:Psychometrics; D012189:Retrospective Studies; D053201:Urinary Bladder, Overactive / Q000503:physiopathology / Q000523:psychology; D014549:Urinary Incontinence / Q000503:physiopathology* / Q000523:psychology; D014563:Urodynamics / Q000502:physiology*
affective symptoms; anxiety; conventional urodynamic study; depression; detrusor overactivity; overactive bladder syndrome