Interaction between episodic and semantic memory networks in the acquisition and consolidation of novel spoken words.
When a novel word is learned, its memory representation is thought to undergo a process of consolidation and integration. In this study, we tested whether the neural representations of novel words change as a function of consolidation by observing brain activation patterns just after learning and again after a delay of one week. Words learned with meanings were remembered better than those learned without meanings. Both episodic (hippocampus-dependent) and semantic (dependent on distributed neocortical areas) memory systems were utilised during recognition of the novel words. The extent to which the two systems were involved changed as a function of time and the amount of associated information, with more involvement of both systems for the meaningful words than for the form-only words after the one-week delay. These results suggest that the reason the meaningful words were remembered better is that their retrieval can benefit more from these two complementary memory systems.
Radboud University, Behavioural Science Institute, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands; Radboud University, Donders Institute for Brain, Cognition and Behaviour, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address: Atsuko.Takashima@donders.ru.nl.
Atsuko
A
Takashima
Radboud University, Behavioural Science Institute, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands; Radboud University, Donders Institute for Brain, Cognition and Behaviour, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Iske
I
Bakker
Pennsylvania State University, Department of Psychology, University Park, PA 16802, USA.
Janet G
JG
van Hell
Radboud University, Behavioural Science Institute, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands; Radboud University, Donders Institute for Brain, Cognition and Behaviour, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands.
Gabriele
G
Janzen
Radboud University, Behavioural Science Institute, P.O. Box 9104, 6500 HE Nijmegen, The Netherlands; Radboud University, Donders Institute for Brain, Cognition and Behaviour, P.O. Box 9101, 6500 HB Nijmegen, The Netherlands; Max Planck Institute for Psycholinguistics, P.O. Box 310, 6500 AH Nijmegen, The Netherlands.
James M
JM
McQueen
D000293:Adolescent; D000328:Adult; D001921:Brain / Q000502:physiology; D005260:Female; D006624:Hippocampus / Q000502:physiology; D006801:Humans; D008297:Male; D008568:Memory / Q000502:physiology*; D061212:Memory, Episodic; D012660:Semantics; D013067:Speech Perception / Q000502:physiology*; D013997:Time Factors; D055815:Young Adult
Angular gyrus; Consolidation; Episodic memory; Hippocampus; Inferior frontal gyrus; Integration; Novel word learning; Posterior middle temporal gyrus; Semantic memory; fMRI