Ultrastructure of Cardiomyocytes and Blood Capillary Endotheliocytes in the Myocardium under Conditions of Experimental Mechanical Injury to the Heart.
We studied ultrastructural changes in cardiomyocytes and blood capillary endotheliocytes in the ventricular myocardium in response to mechanical injury of the heart of varying severity in Wistar rats. Acute alterative changes in cardiomyocyte and endotheliocyte ultrastructure indicate impairment of the energy-producing, contractile, and protein-synthesizing functions of the cells after mechanical injury. These disorders play the key role in the development of acute contractile insufficiency of the myocardium in mechanical injury to the heart.
Department of Forensic Medicine, Novosibirsk State Medical University, Novosibirsk, Russia.
V P
VP
Novoselov
Department of Forensic Medicine, Novosibirsk State Medical University, Novosibirsk, Russia. dr.serg62@yandex.ru.
S V
SV
Savchenko
Department of Forensic Medicine, Novosibirsk State Medical University, Novosibirsk, Russia.
A N
AN
Porvin
Department of Forensic Medicine, Novosibirsk State Medical University, Novosibirsk, Russia.
D A
DA
Koshlyak
Department of Pathology, Novosibirsk State Medical University, Novosibirsk, Russia.
A P
AP
Nadev
Department of Pathology, Novosibirsk State Medical University, Novosibirsk, Russia.
T A
TA
Ageeva
Department of Hospital and Pediatric Surgery, Novosibirsk State Medical University, Novosibirsk, Russia.
Yu V
YV
Chikinev
Department of Hospital and Pediatric Surgery, Novosibirsk State Medical University, Novosibirsk, Russia.
A S
AS
Polyakevich
D000818:Animals; D042783:Endothelial Cells / Q000473:pathology; D004730:Endothelium, Vascular / Q000473:pathology*; D006335:Heart Injuries / Q000473:pathology*; D046529:Microscopy, Electron, Transmission; D008929:Mitochondria, Heart / Q000473:pathology; D009206:Myocardium / Q000473:pathology; D032383:Myocytes, Cardiac / Q000473:pathology*; D009210:Myofibrils / Q000473:pathology; D017208:Rats, Wistar
experiment; heart contusion; ultrastructure