Statin-induced rhabdomyolysis in patient with renal failure and underlying undiagnosed hypothyroidism.
Rhabdomyolysis is a syndrome characterized by muscle necrosis which causes the release of myoglobin into the bloodstream. The manifestations of this syndrome range from asymptomatic elevation of serum muscle enzymes to life-threatening cases associated with extremely high enzyme levels, electrolyte imbalance, and acute renal failure. Symptoms of rhabdomyolysis include dark urine, muscle weakness, and fatigue. Statins are commonly used drugs for the prevention and management of dyslipidemia. We present an interesting and critical case on statin-induced rhabdomyolysis with renal failure and previously undiagnosed idiopathic hypothyroidism.
Department of Critical Care, Dr. L H Hiranandani Hospital, Mumbai, Maharashtra, India.
Sachinkumar N
SN
Ambapkar
Department of Critical Care, Dr. L H Hiranandani Hospital, Mumbai, Maharashtra, India.
Naresh
N
Shetty
Department of Critical Care, Dr. L H Hiranandani Hospital, Mumbai, Maharashtra, India.
Arpita
A
Dwivedy
Lead Medical, Asia Pacific region, Ferring Pharmaceuticals Pvt. Ltd., Mumbai, Maharashtra, India.
Harshad Onkarrao
HO
Malve
Atorvastatin; foot drop; myopathy; myositis