Bartter Syndrome with Normal Aldosterone Level: An Unusual Presentation.
Bartter syndrome (BS) is a hereditary disease, with an autosomal recessive or autosomal dominant mode of transmission. It is characterized by salt wasting hypochloraemic, hypokalaemic metabolic alkalosis and hyperreninaemia with normal blood pressure. The primary defect is in the thick ascending limb of loop of Henle (TAL). Herein, we report a case that had typical features of BS like severe dehydration, severe hypokalaemia, metabolic alkalosis and failure to thrive but had normal aldosterone level which is very uncommon.
Dr Syed Saimul Huque, Associate Professor, Department of Paediatric Nephrology, Bangabandhu Sheikh Mujib Medical University, Shahbagh, Dhaka, Bangladesh; E-mail: saimul264@yahoo.com.
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Rahman
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Khatun
D000450:Aldosterone / Q000097:blood*; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000008:administration & dosage; D000959:Antihypertensive Agents / Q000008:administration & dosage; D001459:Bangladesh; D001477:Bartter Syndrome / Q000175:diagnosis* / Q000188:drug therapy* / Q000378:metabolism; D019587:Dietary Supplements; D004656:Enalapril / Q000008:administration & dosage; D005260:Female; D005440:Fluid Therapy; D006801:Humans; D007052:Ibuprofen / Q000008:administration & dosage; D007223:Infant; D011188:Potassium / Q000008:administration & dosage; D016896:Treatment Outcome
D000894:Anti-Inflammatory Agents, Non-Steroidal; D000959:Antihypertensive Agents; D000450:Aldosterone; D004656:Enalapril; D011188:Potassium; D007052:Ibuprofen