New molecular probes of vascular inflammation.
New molecular imaging approaches featuring the assessment of inflammatory processes in the vascular wall on top of existing anatomic and functional vessel imaging procedures could emerge as decisive tools for the understanding and prevention of cardiovascular events. In this respect imaging approaches addressing specific molecular and cellular targets in atherosclerosis are of high interest. This review summarizes the rationale and current status of nuclear imaging probes which possess high translational potential.
Department of Nuclear Medicine, University Hospital Münster, Münster, Germany - schafmi@uni-muenster.de.
Alexis
A
Vrachimis
Lisa
L
Honold
Andreas
A
Faust
Sven
S
Hermann
Michael
M
Schäfers
D000818:Animals; D017209:Apoptosis; D050197:Atherosclerosis / Q000000981:diagnostic imaging*; D002114:Calcinosis / Q000000981:diagnostic imaging; D002309:Cardiology / Q000379:methods; D004195:Disease Models, Animal; D019788:Fluorodeoxyglucose F18 / Q000737:chemistry; D006801:Humans; D000860:Hypoxia; D007249:Inflammation / Q000097:blood*; D051379:Mice; D015335:Molecular Probes / Q000737:chemistry*; D009389:Neovascularization, Pathologic / Q000000981:diagnostic imaging; D000072078:Positron Emission Tomography Computed Tomography; D049268:Positron-Emission Tomography; D057170:Translational Research, Biomedical
D015335:Molecular Probes; D019788:Fluorodeoxyglucose F18