The effects of cognitive remediation therapy using the frontal/executive program for autism spectrum disorder.
The cognitive features and treatment of autism spectrum disorder have been the subject of much debate in recent years. Therapeutic approaches to date have focused on skills acquisition, support tailored to the characteristics of autism spectrum disorder, and interventions in social cognitive functioning; there have been few reports describing interventions aimed at neurocognitive dysfunction. In this study, we focus on impairment of executive functioning in autism spectrum disorder patients and investigate improvements in executive functioning and their generalization to social functioning.



The intervention adopted for this study was cognitive remediation therapy using the frontal/executive program. To investigate the effectiveness of frontal/executive program, 15 subjects who consented to participate in the study were randomly assigned to an intervention group or control group. Frontal/executive program was administered to the intervention group for about six months. Both groups were evaluated using the same scales: BACS-J, WCST, and CPT for cognitive assessment; SCoRS-J, GAF, and LASMI for social functioning; and GSE for self-efficacy.



Both groups had lower scores for cognitive functioning than normal individuals at baseline. After completion of frontal/executive program, the intervention group showed improved performance on BACS-J for overall score, digit sequencing, verbal fluency, and Tower of London tasks. Improvements were also seen on SCoRS-J and LASMI scales of social functioning.



This was the first study to use frontal/executive program to focus on neurocognitive dysfunction in autism spectrum disorder patients. Frontal/executive program is effective in improving impaired executive functioning in autism spectrum disorder patients and may also lead to improvements in some aspects of social functioning.
Department of Functioning and Disability, Faculty of Health Science, Hokkaido University, Hokkaido, Japan Asahiyama Hospital, Hokkaido, Japan.
Maki
M
Miyajima
Asahiyama Hospital, Hokkaido, Japan.
Hidetoshi
H
Omiya
Asahiyama Hospital, Hokkaido, Japan.
Kiyoko
K
Yamashita
Asahiyama Hospital, Hokkaido, Japan.
Tomoki
T
Miyata
Asahiyama Hospital, Hokkaido, Japan.
Kenji
K
Yambe
Department of Psychology, School of Medicine, University of Toyama, Toyama, Japan.
Mie
M
Matsui
Department of Functioning and Disability, Faculty of Health Science, Hokkaido University, Hokkaido, Japan kdenda@med.hokudai.ac.jp.
Kenzo
K
Denda
D000328:Adult; D000067877:Autism Spectrum Disorder / Q000523:psychology* / Q000628:therapy*; D003071:Cognition; D000072466:Cognitive Remediation; D056344:Executive Function / Q000502:physiology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D012917:Social Adjustment; D016896:Treatment Outcome
autism spectrum disorder; cognitive disorders; executive function; rehabilitation