Induction of the Adaptive Response in Mice Exposed to He-Ne Laser and X-Ray Radiation.
We studied the dose-dependent induction of in vivo adaptive response in the bone marrow and blood of mice exposed to low-intensity radiation of He-Ne laser (633 nm) and X-ray radiation by the severity of cytogenetic injury and intensity of ROS production, respectively. Induction of the adaptive response in mice preexposed to He-Ne laser and X-ray radiation depended on the adaptive dose and the interval between the adaptive and main doses and correlated with changes in ROS generation. The adaptive response after exposure to low-intensity ionizing and non-ionizing radiation was observed in the same dose range, which attests to similar mechanisms of its induction.
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia. szaichkina@yandex.ru.
S I
SI
Zaichkina
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
A R
AR
Dyukina
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
O M
OM
Rozanova
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
N B
NB
Simonova
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
S P
SP
Romanchenko
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
S S
SS
Sorokina
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Russia.
D T
DT
Zakrzhevskaya
Institute of Problems of Laser and Information Technologies, Russian Academy of Sciences, Troitsk, Russia.
V I
VI
Yusupov
Institute of Problems of Laser and Information Technologies, Russian Academy of Sciences, Troitsk, Russia.
V N
VN
Bagratashvili
D000222:Adaptation, Physiological / Q000528:radiation effects*; D000818:Animals; D004307:Dose-Response Relationship, Radiation; D007834:Lasers; D008297:Male; D051379:Mice; D017382:Reactive Oxygen Species / Q000378:metabolism; D014965:X-Rays
D017382:Reactive Oxygen Species
He-Ne laser; adaptive response; mice; micronucleus test; reactive oxygen substances