A case of mitochondrial disease with severe left ventricular hypertrophy.
A 35-year-old woman was admitted for progressive dyspnea with lower limb edema. Transthoracic echocardiography showed severe left ventricular hypertrophy (LVH) and heart failure with preserved ejection fraction (HFPEF). Electron microscopy of an endomyocardial biopsy sample revealed a high density of mitochondria of abnormal size and shape. We report a case of mitochondrial disease with severe LVH and HFPEF.
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Kosuke
K
Uchida
Division of Laboratory, Yamaguchi University Hospital, Minamikogushi, Ube, Yamaguchi, 755-8505, Japan. kzmurata@yamaguchi-u.ac.jp.
Kazuya
K
Murata
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Shigeki
S
Kobayashi
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Hiroshi
H
Nakamura
Advanced Medical Emergency and Critical Care Center, Yamaguchi University Hospital, Ube, Japan.
Yasuaki
Y
Wada
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Shinichi
S
Okuda
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Chikage
C
Oshita
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Takehisa
T
Susa
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Wakako
W
Murakami
Department of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, Ube, Japan.
Masunori
M
Matsuzaki
Heart failure with preserved ejection fraction; Left ventricular hypertrophy; Mitochondrial disease; Serum lactate