Pregnancy in Budd-Chiari Syndrome: Case Report and Proposed Risk Score.
Due to its rarity, experience with pregnancy in Budd-Chiari syndrome (BCS) is limited. With the advent of new treatment modalities, transjugular intrahepatic portosystemic shunt in particular, numbers of affected women seeking pregnancy with BCS are expected to rise. Here, we use a case that ended lethal within 2 years after delivery to discuss the effect of pregnancy on BCS and vice versa, and to highlight the necessity of a multidisciplinary teamwork. Additionally, a risk classification is proposed which may serve as a framework for preconception counseling and assist in the establishment and evaluation of treatment algorithms; its criteria need to be defined and assessed for their applicability in further studies.
From the Department of Obstetrics and Prenatal Medicine (WMM, AMR, UG), University Bonn Medical School; Department of Internal Medicine I (VH, JT); Institute of Experimental Hematology and Transfusion Medicine (BP); Department of Radiology (CM); and Department of General (JMP), Visceral, Thoracic, and Vascular Surgery, University Bonn Medical School, Bonn, Germany.
Waltraut M
WM
Merz
Anna M
AM
Rüland
Valeria
V
Hippe
Bernd
B
Poetzsch
Carsten
C
Meyer
Joerg M
JM
Pollok
Ulrich
U
Gembruch
Jonel
J
Trebicka
D000328:Adult; D006502:Budd-Chiari Syndrome / Q000503:physiopathology / Q000601:surgery*; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000008:administration & dosage; D006801:Humans; D010348:Patient Care Team / Q000458:organization & administration; D019168:Portasystemic Shunt, Transjugular Intrahepatic / Q000379:methods*; D011247:Pregnancy; D018570:Risk Assessment; D012307:Risk Factors
D006495:Heparin, Low-Molecular-Weight