Current role for bone absorptiometry.
Bone mineral density (BMD) measurement using dual-energy X-ray absorptiometry (DXA) is a key contributor to the management of bone fragility syndromes, most notably postmenopausal osteoporosis. Experimental studies of bone biomechanics have established that an accurate marker for mechanical strength is areal BMD (aBMD, g/cm2). Areal BMD contributes 70% of mechanical strength at the femur and 40% at the spine. Two decades after the T-score was first introduced (World Health Organization, 1994), changes have occurred in the indications of DXA and in the interpretation of its results for the diagnosis, prognosis, and treatment of osteoporosis.
Inserm U1153, Université Paris Descartes, 75006 Paris, France; Département de Rhumatologie, Hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France. Electronic address: christian.roux@aphp.fr.
Christian
C
Roux
Inserm U1153, Université Paris Descartes, 75006 Paris, France; Département de Rhumatologie, Hôpital Cochin, 27, rue du Faubourg-Saint-Jacques, 75014 Paris, France.
Karine
K
Briot
D015502:Absorptiometry, Photon / Q000379:methods*; D000368:Aged; D015519:Bone Density / Q000502:physiology; D050071:Bone Density Conservation Agents / Q000008:administration & dosage*; D005260:Female; D005598:Fractures, Spontaneous / Q000517:prevention & control; D006801:Humans; D008875:Middle Aged; D008991:Monitoring, Physiologic / Q000379:methods; D010024:Osteoporosis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000453:epidemiology; D015663:Osteoporosis, Postmenopausal / Q000000981:diagnostic imaging* / Q000188:drug therapy* / Q000453:epidemiology*; D011379:Prognosis; D018570:Risk Assessment; D012380:Role; D012720:Severity of Illness Index
D050071:Bone Density Conservation Agents
Dual-energy X-ray absorptiometry; Fracture; Osteoporosis; Treatment monitoring