High doses of incobotulinumtoxinA for the treatment of post-stroke spasticity: are they safe and effective?
a Physical Medicine and Rehabilitation Section-'OORR Hospital' , University of Foggia , Foggia , Italy.
Andrea
A
Santamato
a Physical Medicine and Rehabilitation Section-'OORR Hospital' , University of Foggia , Foggia , Italy.
Maurizio
M
Ranieri
b Geriatric Medicine-Memory Unit and Rare Disease Centre , University of Bari Aldo Moro , Bari , Italy.
Vincenzo
V
Solfrizzi
c Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.
Madia
M
Lozupone
d Department of Medical Sciences , UOC Physical Medicine and Rehabilitation, AOU 'O.V.E-Policlinico' , Catania , Italy.
Michele
M
Vecchio
e Institute of Neurology , Catholic University of Sacred Heart , Rome , Italy.
Antonio
A
Daniele
f Gerontology-Geriatrics Research Laboratory , IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.
Antonio
A
Greco
f Gerontology-Geriatrics Research Laboratory , IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.
Davide
D
Seripa
c Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.|g Department of Clinical Research in Neurology , University of Bari Aldo Moro, 'Pia Fondazione Cardinale G. Panico' , Lecce , Italy.
Giancarlo
G
Logroscino
c Neurodegenerative Disease Unit, Department of Basic Medicine, Neuroscience, and Sense Organs , University of Bari Aldo Moro , Bari , Italy.|f Gerontology-Geriatrics Research Laboratory , IRCCS Casa Sollievo della Sofferenza , Foggia , Italy.|g Department of Clinical Research in Neurology , University of Bari Aldo Moro, 'Pia Fondazione Cardinale G. Panico' , Lecce , Italy.
Francesco
F
Panza
D019274:Botulinum Toxins, Type A / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D006801:Humans; D009128:Muscle Spasticity / Q000188:drug therapy* / Q000209:etiology; D009465:Neuromuscular Agents / Q000008:administration & dosage* / Q000009:adverse effects / Q000627:therapeutic use; D020521:Stroke / Q000150:complications*
D009465:Neuromuscular Agents; D019274:Botulinum Toxins, Type A; C545476:incobotulinumtoxinA
Upper motor neuron syndrome; adverse effects; botulinum toxin type A; incobotulinumtoxinA; safety; spasticity; stroke