[Intracranial tumors and epileptic seizures: treatment principles].
Epileptic seizures represent a relatively frequent issue in patients with intracranial neoplasms, and very frequently imply the start of an antiepileptic treatment as secondary prophylaxis. Even if the current level of evidence is relatively low, compounds with a limited risk of pharmacokinetic interactions are clearly preferred. Levetiracetam is probably the most prescribed agent in this setting, while pregabalin, valproate, lacosamide and lamotrigine are valuable alternatives. The treatment choice has to consider the different profiles of side effects and should be tailored to each patient. In this setting, a multidisciplinary approach including general practicioner, oncologist and neurologist is strongly advocated.
Andrea O
AO
Rossetti
Serge
S
Vulliémoz
D000927:Anticonvulsants / Q000009:adverse effects / Q000627:therapeutic use*; D001932:Brain Neoplasms / Q000150:complications*; D004827:Epilepsy / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D006801:Humans; D033183:Interdisciplinary Communication; D055502:Secondary Prevention / Q000379:methods
D000927:Anticonvulsants