[Thrombotic thrombocytopenic purpura after circumcision].
After circumcision, a young man developed a wound healing disorder. After presenting to our hospital for further wound care, laboratory results showed acute renal failure with hemolytic anemia and thrombocytopenia, which led to the diagnosis of postoperative thrombotic thrombocytopenic purpura (TTP). After therapy with plasma exchange and immunosuppressive therapy with prednisolone and rituximab, the patient recovered with normalization of laboratory results. The TTP is associated with low activity of ADAMTS13 with microvascular platelet aggregation and hemolytic anemia.
Abteilung für Urologie, Asklepios Klinik Barmbek, Rübenkamp 220, 22291, Hamburg, Deutschland. f.schott@asklepios.com.
F
F
Schott
Abteilung für Urologie, Asklepios Klinik Barmbek, Rübenkamp 220, 22291, Hamburg, Deutschland.
A J
AJ
Gross
Abteilung für Urologie, Asklepios Klinik Barmbek, Rübenkamp 220, 22291, Hamburg, Deutschland.
C
C
Netsch
Abteilung für Nephrologie, Asklepios Klinik Barmbek, Hamburg, Deutschland.
S
S
Segerer
D000328:Adult; D002944:Circumcision, Male / Q000009:adverse effects*; D003131:Combined Modality Therapy / Q000379:methods; D003937:Diagnosis, Differential; D006801:Humans; D007166:Immunosuppressive Agents / Q000627:therapeutic use*; D008297:Male; D010951:Plasma Exchange / Q000379:methods*; D011697:Purpura, Thrombotic Thrombocytopenic / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D016896:Treatment Outcome
D007166:Immunosuppressive Agents
Anemia, hemolytic; Moschcowitz disease; Phimosis; Thrombocytopenia; Wound healing