Size Regulation: Big Insights from Little Cells.
Reporting in Cell, Harris and Theriot (2016) use modeling and quantitative imaging to analyze bacterial cell growth and division. By manipulating surface and volume growth rates, the authors provide insight into bacterial cell size regulation and propose that a threshold level of unincorporated cell wall material specifies when cells divide.
Department of Cell and Developmental Biology, University of Pennsylvania, 421 Curie Boulevard, 1151 BRB II/III, Philadelphia, PA 19104, USA.
Hui
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Chen
Department of Cell and Developmental Biology, University of Pennsylvania, 421 Curie Boulevard, 1151 BRB II/III, Philadelphia, PA 19104, USA; Department of Bioengineering, University of Pennsylvania, 421 Curie Boulevard, 1151 BRB II/III, Philadelphia, PA 19104, USA. Electronic address: mattgood@upenn.edu.
Matthew C
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Good
D001419:Bacteria / Q000166:cytology*; D016935:Caulobacter crescentus / Q000166:cytology; D004926:Escherichia coli / Q000166:cytology; D008954:Models, Biological