[Collagenous gastritis and colitis in a 10-year-old girl].
There are few data in the literature on microscopic gastritis and colitis in the pediatric population. The diagnosis is often made after the occurrence of complications. We report the case of a 10.5 year-old girl for whom the diagnosis was made several years after the initial symptoms. Test for infections, inflammation, and auto-immunity yielded normal results. Upper endoscopy and colonoscopy revealed an abnormal mucosa. However, histology showed microscopic inflammation and fibrotic lesions in the lamina propria, and a thick subepithelial collagenous band. This led to the diagnosis of collagenous gastritis and colitis. Budesonide treatment resulted in the cessation of diarrhea and significant weight gain. Treatment by oral budesonide indeed seems to be highly effective but relapses are frequent when the treatment is stopped. This case shows the importance of being vigilant regarding transit disorders with impact on growth kinetics. Upper endoscopy and colonoscopy need to be carried out when children have organic diarrhea with normal blood tests.
Clinique universitaire de pédiatrie, CHU de Grenoble, 38000 Grenoble, France.
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Hangard
Clinique universitaire de pédiatrie, CHU de Grenoble, 38000 Grenoble, France.
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Lasfargue
Clinique universitaire de pédiatrie, CHU de Grenoble, 38000 Grenoble, France; Université Grenoble-Alpes, 38000 Grenoble, France. Electronic address: arubio@chu-grenoble.fr.
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Rubio
D002648:Child; D003092:Colitis / Q000175:diagnosis / Q000378:metabolism*; D003094:Collagen / Q000378:metabolism*; D003113:Colonoscopy; D016145:Endoscopy, Digestive System; D005260:Female; D005753:Gastric Mucosa / Q000473:pathology*; D005756:Gastritis / Q000175:diagnosis / Q000378:metabolism*; D006801:Humans
D003094:Collagen