Successful Treatment of Refractory Hypoxemia Secondary to Disseminated Histoplasmosis Using Extracorporeal Membrane Oxygenation Support.
Refractory hypoxemia secondary to acute respiratory distress syndrome (ARDS) is associated with high mortality. Extracorporeal membraneoxygenation (ECMO) is an accepted strategy for treating refractory hypoxemia in patients with ARDS but is relatively contraindicated in the setting of systemic infections. We present a case of successful ECMO use in a host with refractory hypoxemia secondary to disseminated histoplasmosis with fungemia and discuss our management approach to this difficult patient.
From the *Division of Anesthesia and Critical Care Medicine, Department of Anesthesiology, †Division of Infectious Diseases, Department of Medicine, and ‡Department of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota.
Brendan T
BT
Wanta
Harmony L
HL
Tyner
John K
JK
Bohman
Larry M
LM
Baddour
D015199:Extracorporeal Membrane Oxygenation / Q000379:methods*; D005260:Female; D006660:Histoplasmosis / Q000150:complications* / Q000000981:diagnostic imaging / Q000628:therapy*; D006801:Humans; D000860:Hypoxia / Q000000981:diagnostic imaging / Q000209:etiology* / Q000628:therapy*; D016896:Treatment Outcome; D055815:Young Adult