A prospective multicenter European study on flexible ureterorenoscopy for the management of renal stone.
OBJECTIVE
The aim of this study was to describe the outcomes and the complications of retrograde intrarenal surgery (RIRS) for renal stones in a multi-institutional working group.


METHODS
From 2012 to 2014, we conducted a prospective study including all RIRS performed for kidney stones in 4 European centers. Demographic information, disease characteristics, and perioperative and postoperative data were gathered. Patients and stone data, procedure characteristics, results and safety outcomes were analyzed and compared by descriptive statistics. Complications were reported using the standardized Clavien system.


RESULTS
Three hundred and fifty-six patients underwent 377 RIRS with holmium laser lithotripsy for renal stones. The RIRS was completed in all patients with a mean operative time of 63.5 min. The stone-free status was confirmed endoscopically and through fluoroscopic imaging after the first procedure in 73.6%. The second procedure was performed in twenty patients (5.6%) achieving an overall stone free rate of 78.9%. The overall complication rate was 15.1%. Intra-operative and post-operative complications were seen in 24 (6.7%) and 30 (8.4%) cases, respectively.


CONCLUSIONS
RIRS is a minimally invasive procedure with good results in terms of stone-free and complications rate.
Dipartimento di Urologia, "S. Pio da Pietrelcina" Hospital, Vasto (CH), Italia.
Francesco
F
Berardinelli
Centro di pietra presso il Dipartimento di Urologia, Humanitas centro clinico e di ricerca, Rozzano, Italia.
Silvia
S
Proietti
Dipartimento di Urologia, "S. Pio da Pietrelcina" Hospital, Vasto (CH), Italia.
Luca
L
Cindolo
Dipartimento di Urologia, "S. Pio da Pietrelcina" Hospital, Vasto (CH), Italia.
Fabrizio
F
Pellegrini
Centro di pietra presso il Dipartimento di Urologia, Humanitas centro clinico e di ricerca, Rozzano, Italia.
Roberto
R
Peschechera
Department of Urology, Craigavon Area Hospital, Portadown (UK).
Hennessey
H
Derek
Urologische Klinik, Medizinische Universität Graz, Austria.
Orietta
O
Dalpiaz
Dipartimento di Urologia, "S. Pio da Pietrelcina" Hospital, Vasto (CH), Italia.
Luigi
L
Schips
Centro di pietra presso il Dipartimento di Urologia, Humanitas centro clinico e di ricerca, Rozzano, Italia.
Guido
G
Giusti
D000328:Adult; D000368:Aged; D004867:Equipment Design; D005060:Europe; D005260:Female; D005471:Fluoroscopy / Q000379:methods; D006801:Humans; D007669:Kidney Calculi / Q000601:surgery*; D007902:Length of Stay; D017602:Lithotripsy, Laser / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D061646:Operative Time; D011183:Postoperative Complications; D011446:Prospective Studies; D015203:Reproducibility of Results; D016896:Treatment Outcome; D020709:Ureteroscopes; D018666:Ureteroscopy / Q000009:adverse effects / Q000295:instrumentation* / Q000379:methods*