[Wild-type transthyretin-related cardiac amyloidosis and degenerative aortic stenosis: Two inter-related pathologies in the elderly].
Wild-type transthyretin-related cardiac amyloidosis (ATTRwt) and degenerative aortic stenosis share a common demographic and clinical profile. It was recently suggested that some of the complications arising during and after transcatheter aortic valve replacement (TAVR) could be due to a co-existing cardiac amyloidosis. In a series of autopsies of patients who had undergone TAVR, researchers found ATTR amyloidosis in one third of the cases. A report is presented on two patients with aortic stenosis who were diagnosed with ATTRwt when they were about to undergo a TAVI. ATTRwt is a slowly progressing disease so we need to review the decisions on the therapeutic approach in these patients.
Servicio de Cardiología, Hospital General Universitario de Albacete, Albacete, España. Electronic address: sofia.caleron@gmail.com.
Sofía
S
Calero Núñez
Servicio de Cardiología, Hospital General Universitario de Albacete, Albacete, España.
Antonia
A
Tercero Martínez
Servicio de Cardiología, Hospital General Universitario de Albacete, Albacete, España.
Juan Carlos
JC
García López
Servicio de Cardiología, Hospital General Universitario de Albacete, Albacete, España.
Jesús
J
Jiménez-Mazuecos
D000369:Aged, 80 and over; D028227:Amyloid Neuropathies, Familial / Q000150:complications*; D001024:Aortic Valve Stenosis / Q000150:complications*; D006801:Humans; D008297:Male
Amiloidosis cardiaca senil; Anciano; Aortic stenosis; Elderly; Estenosis aórtica; Implante percutáneo de prótesis valvular aórtica; Transcatheter aortic valve replacement; Wild-Type Transthyretin-related Cardiac Amyloidosis