Clinical Features of Genetic Cardiac Diseases Related to Potassium Channelopathies.
Genetic cardiac diseases related to potassium channelopathies are a group of relatively rare syndromes that includes long QT syndrome, short QT syndrome, Brugada syndrome, and early repolarization syndrome. Patients with these syndromes share a propensity for the development of life-threatening ventricular arrhythmias in the absence of significant cardiac structural abnormalities. Familial atrial fibrillation has also been associated with potassium channel dysfunction but differs from the other syndromes by being a rare cause of a common condition. This article focuses on the clinical features, diagnosis, and management of these syndromes.
Department of Cardiology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 64239, Israel.
Arnon
A
Adler
Department of Cardiology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 64239, Israel. Electronic address: saviskin@tasmc.health.gov.il.
Sami
S
Viskin
D001145:Arrhythmias, Cardiac / Q000175:diagnosis / Q000235:genetics / Q000503:physiopathology; D004562:Electrocardiography; D006801:Humans; D015221:Potassium Channels / Q000235:genetics*
D015221:Potassium Channels
Brugada syndrome; Early repolarization syndrome; Familial atrial fibrillation; Inherited arrhythmias; Long QT syndrome; Potassium channels; Short QT syndrome; Sudden cardiac death