[Research progress on application of carbon nanotubes in bone tissue engineering scaffold].
Carbon nanotubes possess excellent mechanical and electrical properties and demonstrate broad application prospects in medical fields. Carbon nanotubes are composed of inorganic materials, natural biodegradable polymer or synthetic biodegradable polymer. The composite bone tissue engineering scaffolds are constructed by particle-hole method, lyophilization, microsphere aggregation method, electrostatic spinning or three-dimensional printing. Composite scaffolds overcome the shortcomings of single material and have good biocompatibility, osteoconduction and osteoinduction. With the study of surface chemistry, toxicology, and biocompatibility, a degradable "human-friendly" carbon nanotubes composite bone tissue scaffold will be available; and under the drive of new fabrication techniques, the clinical application of carbon nanotubes composite bone tissue engineering scaffolds will be better developed.
Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Mengzhu
M
Yao
Hangzhou Solipharma Co. Ltd, Hangzhou 310058,China.
Xiaoxia
X
Sheng
Department of Stomatology,the First Affiliated Hospital,Zhejiang University School of Medicine, Hangzhou 310009, China.
Jun
J
Lin
Institute of Pharmaceutics, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China. gaojianqing@zju.edu.cn.
Jianqing
J
Gao
D001672:Biocompatible Materials / Q000737:chemistry; D001846:Bone Development; D006801:Humans; D008863:Microspheres; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011108:Polymers / Q000737:chemistry; D066330:Printing, Three-Dimensional; D023822:Tissue Engineering; D054457:Tissue Scaffolds / Q000737:chemistry*
D001672:Biocompatible Materials; D037742:Nanotubes, Carbon; D011108:Polymers