Innovative radiotherapy of sarcoma: Proton beam radiation.
This review on proton beam radiotherapy (PBT) focusses on an historical overview, cost-effectiveness, techniques, acute and late toxicities and clinical results of PBT for sarcoma patients. PBT has gained its place among the armamentarium of modern radiotherapy techniques. For selected patients, it can be cost-effective.
Department of Radiation Oncology, Harvard Medical School, Boston, MA, 02115, USA; Department of Radiation Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA; Francis H. Burr Proton Therapy Center, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA; Center for Sarcoma and Connective Tissue Oncology, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, 02114, USA. Electronic address: tdelaney@mgh.harvard.edu.
Thomas F
TF
DeLaney
Radiation Oncology, The Netherlands Cancer Institute, Antoni Leeuwenhoek Hospital, Plesmanlaan 121, Amsterdam, 1066 CX, The Netherlands. Electronic address: r.haas@nki.nl.
Rick L M
RL
Haas
D003362:Cost-Benefit Analysis; D006801:Humans; D061766:Proton Therapy / Q000009:adverse effects / Q000191:economics / Q000379:methods*; D011832:Radiation Injuries / Q000209:etiology; D012509:Sarcoma / Q000532:radiotherapy*
Proton beam radiation; Sarcoma