Regioselective Intermolecular Diamination and Aminooxygenation of Alkenes with Saccharin.
Palladium catalysis enables the regioselective difunctionalization of alkenes using saccharin as the nitrogen source in the initial step of aminopalladation. Depending on the reaction conditions, diamination or aminooxygenation pathways can be accessed using hypervalent iodine reagents as the terminal oxidants. The aminooxygenation of allylic ethers originates from an unprecedented ambident behavior of saccharin. The participating palladium catalysts contain a palladium-saccharide unit. Two representative complexes of this type could be isolated and characterized.
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av Països Catalans 16, 43007 Tarragona, Spain.
Claudio
C
Martínez
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av Països Catalans 16, 43007 Tarragona, Spain.|Departamento de Química Orgánica, Facultad de Química, Pontificia Universidad Católica de Chile , Vicuña Mackenna 4860, Casilla 306, Santiago 22, Chile.
Edwin G
EG
Pérez
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av Països Catalans 16, 43007 Tarragona, Spain.
Álvaro
Á
Iglesias
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av Països Catalans 16, 43007 Tarragona, Spain.
Eduardo C
EC
Escudero-Adán
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av Països Catalans 16, 43007 Tarragona, Spain.|Catalan Institution for Research and Advanced Studies (ICREA) , Pg Lluís Companys 23, 08010 Barcelona, Spain.
Kilian
K
Muñiz