18F-FDG PET/CT Osteometabolic Activity in Metastatic Parathyroid Carcinoma.
Parathyroid cancer is an uncommon type of malignancy, which is frequently associated with poor prognosis. Clinical manifestations are caused by elevated serum calcium and parathyroid hormone (PTH). Diagnostic imaging studies as neck ultrasonography, technetium Tc Tc-sestamibi whole body scintigraphy, CT, and MR are already established tools for this malignancy. Nevertheless, the role of F-FDG PET/CT remains unknown in this scenario, with few published studies in literature. Hence, in this article, we aimed to report an illustrative case of increased skeletal FDG uptake associated with high calcium and PTH levels.
From the Division of Nuclear Medicine, São Paulo State Cancer Institute, São Paulo, Brazil.
Rômulo Hermeto Bueno
RH
do Vale
Marcelo Araújo
MA
Queiroz
Artur Martins Novaes
AM
Coutinho
Carlos Alberto
CA
Buchpiguel
Marcos Roberto
MR
de Menezes
D001859:Bone Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000556:secondary; D002118:Calcium / Q000097:blood; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000556:secondary; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006801:Humans; D008175:Lung Neoplasms / Q000097:blood / Q000000981:diagnostic imaging* / Q000556:secondary; D008875:Middle Aged; D010281:Parathyroid Hormone / Q000097:blood; D010282:Parathyroid Neoplasms / Q000097:blood / Q000473:pathology*; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics
D010281:Parathyroid Hormone; D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18; D002118:Calcium