Early- and mid-term outcomes after transcatheter aortic valve implantation. Data from a single-center registry.
BACKGROUND
Transcatheter aortic valve implantation (TAVI) is a less invasive treatment option for elderly, high-risk patients with symptomatic severe aortic stenosis (AS) than aortic valve replacement. More importantly, TAVI improves survival and quality of life as compared to medical treatment in inoperable patients.


OBJECTIVE
To assess early- and mid-term clinical outcomes after TAVI.


METHODS
All consecutive high-risk patients with severe symptomatic AS undergoing TAVI from November 2008 to August 2014 were enrolled. The clinical and procedural characteristics, as well as clinical outcomes including mortality during 12-month follow-up, were assessed.


RESULTS
A total of 101 consecutive patients underwent TAVI for native aortic valve stenosis (100%). Patients were elderly, with a median age of 81.0 (76.0-84.0) years, 60.4% were female and 83.2% presented with NYHA III/IV. Median baseline EuroSCORE I and STS scores were 14.0 (10.0-22.5)% and 12.0 (5.0-24.0)%, respectively. The main periprocedural and in-hospital complications were minor vascular complications, bleeding requiring blood transfusions, and the need for a permanent pacemaker. In-hospital, 30-day, 6-month and 12-month mortality rates were 6.9%, 10.9%, 15.8% and 17.8%, respectively.


CONCLUSIONS
A mortality rate of < 20% after 12 months seems acceptable given the high-risk population enrolled.
Institute of Cardiology, Krakow, Poland.
Maciej
M
Bagienski
Institute of Cardiology, Krakow, Poland.
Pawel
P
Kleczynski
Institute of Cardiology, Krakow, Poland.
Artur
A
Dziewierz
Institute of Cardiology, Krakow, Poland.
Lukasz
L
Rzeszutko
Institute of Cardiology, Krakow, Poland.
Danuta
D
Sorysz
Institute of Cardiology, Krakow, Poland.
Jaroslaw
J
Trebacz
Institute of Cardiology, Krakow, Poland.
Robert
R
Sobczynski
Institute of Cardiology, Krakow, Poland.
Marek
M
Tomala
Institute of Cardiology, Krakow, Poland.
Maciej
M
Stapor
Institute of Cardiology, Krakow, Poland.
Andrzej
A
Gackowski
Institute of Cardiology, Krakow, Poland.
Dariusz
D
Dudek
aortic stenosis; high-risk patients; outcomes; registry; transcatheter aortic valve implantation