An Alternate Synthesis of the Capsaicinoids.
Five capsaicinoids, the pungent ingredients of hot peppers, have been efficiently synthesized by a method involving the Wittig reaction between isobutyl triphenylphosphorane and the appropriate lactols (3), followed by the nitrous acid-induced isomerization of the resultant (Z)-olefins (4) to (E)-olefins (5).
a Government Industrial Development Laboratory , Hokkaido, Sapporo 062 , Japan.
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Kaga
a Government Industrial Development Laboratory , Hokkaido, Sapporo 062 , Japan.
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Goto
a Government Industrial Development Laboratory , Hokkaido, Sapporo 062 , Japan.
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Fukuda
a Government Industrial Development Laboratory , Hokkaido, Sapporo 062 , Japan.|b Department of Chemical Process Engineering, Faculty of Engineering , Hokkaido University , Sapporo 060 , Japan.
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