Thermally Induced Carbohydroxylation of Styrenes with Aryldiazonium Salts.
The radical carbohydroxylation of styrenes with aryldiazonium salts has been achieved under mild thermal conditions. A broad range of aryldiazonium salts was tolerated, and the reaction principle based on a radical-polar crossover mechanism could be extended to carboetherification as well as to a two-step, metal-free variant of the Meerwein arylation leading to stilbenes.
Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schuhstrasse 19, 91052, Erlangen, Germany.
Stephanie
S
Kindt
Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schuhstrasse 19, 91052, Erlangen, Germany.
Karina
K
Wicht
Department of Chemistry and Pharmacy, Pharmaceutical Chemistry, Friedrich-Alexander-Universität Erlangen-Nürnberg, Schuhstrasse 19, 91052, Erlangen, Germany. Markus.Heinrich@fau.de.
Markus R
MR
Heinrich
Meerwein arylation; carbohydroxylation; diazonium ions; radical reactions; styrene