At-Home Application of Autologous Platelet Rich Plasma as Treatment for Pressure Sore and Related Anemia.
Pressure sores are a major complication in the bed-ridden older patient. In this report, we present the case of platelet rich plasma (PRP) application for the treatment of a pressure sore in an 88-year-old female affected by transfusion-dependent chronic inflammatory disease anemia associated with the congenital and inherited condition of thalassemic trait carrier. A weekly application schedule was planned athome, given the patient's debilitation and her decreased performance status as well as personal and family difficulties to go as outpatients at our treatment center. After 9 PRP applications, a remarkable sore improvement was achieved so that PRP was discontinued; nevertheless, sore rapidly improved until the full resolution and the complete closing after 4 months from the start of PRP treatment. Noteworthy, transfusion support was interrupted and a significant recovery and a sustained stabilization of hemoglobin (Hb) level at 1 year after ulcer healing were observed. The present case suggests that PRP application, performed athome in our case, is a feasible and effective treatment for pressure sores and related complications.
Andrea
A
Tendas
Hematology Division, S. Eugenio Hospital, Piazzale dell'Umanesimo 10, 00144, Rome, Italy.
Pasquale
P
Niscola
Marco
M
Giovannini
Adriana
A
Costa
Daniela
D
Venditti
Laura
L
Volta
Luigi
L
Malandruccolo
Stefania
S
Sabbadini
Rosa
R
Lasorella
Paolo de
P
Fabritiis
Rita
R
Cassetta
Alessio P
AP
Perrotti
D000369:Aged, 80 and over; D000740:Anemia / Q000150:complications / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D005260:Female; D006699:Home Care Services; D006801:Humans; D053657:Platelet-Rich Plasma / Q000378:metabolism; D003668:Pressure Ulcer / Q000150:complications / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D013789:Thalassemia / Q000150:complications; D016896:Treatment Outcome
Anemia; autologous patient; home care; platelet rich plasma (PRP); pressure sore; thalassemia trait carrier