A childhood acute lymphoblastic leukemia (ALL) case with t(3;17)(q23;p13),t(5;12)(q31;p13),inv(11)(p15q12).
It is known that clonal chromosomal changes in childhood ALL are nonrandom and important markers for diagnosis, prognosis and relaps. In this report we present 4 year-old boy with ALL-L1 who has complex chromosomal rearrangements. Chromosome analysis was performed on bone marrow aspiration sample in relaps after one year from diagnosis and induction chemotherapy. The karyotype was; 46,XY,t(3;17)(q23;p13),t(5;12)(q31;p13),inv(11)(p15q12) [11]/46,XY[8].
Dilhan
D
Kuru
Flükriye
F
Yılmaz
Su Gülsün
SG
Berra
Cengiz
C
Canpolat
Seniha
S
Hacıhanefioğlu
Yelda
Y
Tarkan Argüden
Ayhan
A
Deviren
Deptartment. of Medical Biology, Cerrahpasa Medical School, Istanbul University, 34300 Istanbul, Turkey, Tel: +90 212 414 30 34 Fax: +90 212 586 15 48 E-mail: aysecirakoglu@yahoo.com.
Ayşe
A
Çırakoğlu