Sonohysterosalpingography: a suitable choice in infertility workup.
OBJECTIVE
To evaluate the efficacy, compliance, and cost effectiveness of sonohysterosalpingography (HyCoSy) compared with hysteroscopy for uterine cavity evaluation and compared with RX-hysterosalpingography (RX-HSG) for tubal patency determination.


METHODS
Three hundred and eight infertile patients underwent HyCoSy, hysteroscopy, and RX-HSG. We compared sensitivity, specificity, positive and negative predictive values (PPV and NPV), discomfort level, and cost of all three procedures.


RESULTS
Sensitivity, specificity, PPV, and NPV were higher for HyCoSy than for hysteroscopy but the differences were not significant. HyCoSy also has the same accuracy as RX-HSG. Pain perception and cost were higher for RX-HSG and hysteroscopy than for HyCoSy.


CONCLUSIONS
HyCoSy can be regarded as a procedure for initial evaluation of the uterine cavity and of tubal patency in infertile patients.
Section of Obstetrics and Gynaecology, Department of Biomedical Sciences and Advanced Therapies, University of Ferrara, Corso Giovecca n. 203, 44121, Ferrara, Italy.
Angela
A
Graziano
Section of Obstetrics and Gynaecology, Department of Biomedical Sciences and Advanced Therapies, University of Ferrara, Corso Giovecca n. 203, 44121, Ferrara, Italy.
Giuseppe
G
Lo Monte
Section of Obstetrics and Gynaecology, Department of Biomedical Sciences and Advanced Therapies, University of Ferrara, Corso Giovecca n. 203, 44121, Ferrara, Italy.
Ilaria
I
Soave
Department of Woman Health and Territory's Medicine, University of Rome Sapienza, S. Andrea Hospital, Rome, Italy.
Donatella
D
Caserta
Department of Woman Health and Territory's Medicine, University of Rome Sapienza, S. Andrea Hospital, Rome, Italy.
Massimo
M
Moscarini
Section of Obstetrics and Gynaecology, Department of Biomedical Sciences and Advanced Therapies, University of Ferrara, Corso Giovecca n. 203, 44121, Ferrara, Italy. roberto.marci@unife.it.
Roberto
R
Marci
Hysteroscopy; Infertility; RX-hysterosalpingography; Sonohysterosalpingography; Tubal patency