A new phenolic glycoside from Saprosma merrillii.
A new phenolic glycoside derivative, saproglucoside (1), along with five known phenolic glycoside derivatives (2-6) were isolated from the stems of Saprosma merrillii. The structure of the new compound 1 was determined by 1D and 2D NMR as well as by HRESIMS and hydrolysis. The inhibitory activities of all compounds against seven pathogenic bacteria and two cancer cell lines were evaluated.
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Xue-Ming
XM
Zhou
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Cai-Juan
CJ
Zheng
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Xiao-Ping
XP
Song
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Guang-Ying
GY
Chen
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Yu-Hua
YH
Cao
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
A-Qian
AQ
Huang
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Shao-Hui
SH
Su
b Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica , Nanjing University of Chinese Medicine , Nanjing , Jiangsu , China.
Wen-Xing
WX
Chen
a Key Laboratory of Tropical Medicinal Plant Chemistry of Ministry of Education , College of Chemistry and Chemical Engineering, Hainan Normal University , Haikou , China.
Hui
H
Yang
D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D045744:Cell Line, Tumor; D005960:Glucosides / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D010636:Phenols / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D019666:Rubiaceae / Q000737:chemistry*
D000900:Anti-Bacterial Agents; D000972:Antineoplastic Agents, Phytogenic; D005960:Glucosides; D010636:Phenols; C000617455:saproglucoside
Antibacterial activity; Saprosma merrillii; phenolic glycoside derivatives