Case reports of aconite poisoning in mainland China from 2004 to 2015: A retrospective analysis.
Aconitum species have long been used in key traditional medicines in China, but cases of fatal aconite poisoning have also been reported. This paper presents a review of 40 single and multi-person cases of fatal aconite poisoning. The cases involved 53 victims in mainland China described in 27 case reports published between January 2004 and September 2015. We summarize the details of the case reports in order to highlight the features of fatal aconite-poisoning cases in China, including victims' sex and age, route of intoxication, clinical symptoms, medicolegal autopsy findings, and results of toxicological analysis. Our results indicate a need for legal medical experts encountering cases of fatal aconite poisoning to pay increased attention to the methods used for collecting biological samples. In addition, prevention strategies should focus on increasing public awareness regarding the potential toxicity of Aconitum, harm caused by medicinal liquors containing aconitine, and possibility of Aconitum alkaloids accumulating in the body.
Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, PR China.
Haoran
H
Li
Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, PR China; Key Laboratory of Evidence Science, China University of Political Science and Law, Ministry of Education, Beijing, 100040, PR China.
Liang
L
Liu
Department of Forensic Medicine, Soochow University, Suzhou, 215123, PR China.
Shaohua
S
Zhu
Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan, 430030, PR China. Electronic address: caixe_liu0222@tom.com.
Qian
Q
Liu
D031841:Aconitum / Q000506:poisoning*; D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D004365:Drugs, Chinese Herbal / Q000506:poisoning; D005260:Female; D005502:Food; D053593:Forensic Toxicology; D006801:Humans; D008297:Male; D008516:Medicine, Chinese Traditional; D008875:Middle Aged; D011041:Poisoning / Q000401:mortality; D012189:Retrospective Studies; D017678:Sex Distribution; D055815:Young Adult
D004365:Drugs, Chinese Herbal
Aconitine; Aconitum; Autopsy; Fatal poisoning; Retrospective study