Assessment of Arterial Stiffness in Korean Patients With Psoriasis by Cardio-Ankle Vascular Index.
Many recent studies have suggested that psoriasis, a chronic, inflammatory, immune-mediated skin disease, is associated with increased risk of cardiovascular disease (CVD). We aimed to compare arterial stiffness in psoriasis and control patient groups using the cardio-ankle vascular index (CAVI) and to determine whether psoriasis is an independent risk factor for CVD. A total 103 patients with psoriasis and 103 age- and sex-matched controls were enrolled. Compared with controls, the patients showed a higher CAVI ( P = .03), particularly patients older than 40 years. The duration of psoriasis exhibited a positive correlative tendency with CAVI ( P = .066). Moreover, psoriasis is an independent predictor of arterial stiffness after adjusting for other factors ( P = .011). We suggest that psoriasis can be a risk factor for CVD, and older patients with psoriasis of longer disease duration should be monitored carefully for cardiovascular risk.
1 Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
Byung Gon
BG
Choi
1 Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
Min Jung
MJ
Kim
2 Department of Cardiovascular Medicine, Konkuk University School of Medicine, Seoul, Korea.
Hyun Suk
HS
Yang
1 Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
Yang Won
YW
Lee
1 Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
Yong Beom
YB
Choe
1 Department of Dermatology, Konkuk University School of Medicine, Seoul, Korea.
Kyu Joong
KJ
Ahn
D000367:Age Factors; D000368:Aged; D000842:Ankle / Q000098:blood supply; D055109:Ankle Brachial Index / Q000379:methods; D001794:Blood Pressure / Q000502:physiology; D005260:Female; D006801:Humans; D006973:Hypertension / Q000175:diagnosis* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D011565:Psoriasis / Q000175:diagnosis* / Q000628:therapy; D063177:Pulse Wave Analysis / Q000379:methods; D012307:Risk Factors; D059289:Vascular Stiffness / Q000502:physiology*
arterial stiffness; augmentation index; cardio-ankle vascular index; psoriasis