HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype frequencies in a population of 432 healthy unrelated individuals from Albania.
This paper reports the HLA-A, -B, -C, -DRB1 and -DQB1 allele and haplotype polymorphism in a population of 432 healthy individuals from Albania. First-field HLA genotyping was performed by polymerase chain reaction sequence-specific priming and/or oligonucleotide methods. The data were analyzed statistically using gene counting and Arlequin software packages. No deviation from Hardy Weinberg Equilibrium was detected at any of the loci studied. The HLA genotypic data of the population sample reported here are available publicly in the Allele Frequencies Net Database and they can serve as a reference database for further HLA-based population genetics studies including the Albanian population.
Laboratory of Immunology and Histocompatibility, University of Medicine, Tirana and University Hospital Center "Mother Teresa", Tirana, Albania. Electronic address: gencsulcebe@gmail.com.
Genc
G
Sulcebe
Laboratory of Immunology and Histocompatibility, University of Medicine, Tirana and University Hospital Center "Mother Teresa", Tirana, Albania.
Erkena
E
Shyti
D000415:Albania; D001483:Base Sequence; D005787:Gene Frequency; D005838:Genotype; D015234:HLA-A Antigens / Q000235:genetics*; D015235:HLA-B Antigens / Q000235:genetics*; D059866:HLA-DQ beta-Chains / Q000235:genetics*; D059811:HLA-DRB1 Chains / Q000235:genetics*; D006650:Histocompatibility Testing; D006801:Humans; D008969:Molecular Sequence Data; D044382:Population Groups
D015234:HLA-A Antigens; D015235:HLA-B Antigens; D059866:HLA-DQ beta-Chains; C069051:HLA-DQB1 antigen; D059811:HLA-DRB1 Chains
Albanian population; Anthropology population study; HLA; HLA alleles; HLA haplotypes