The Effect of Salpingectomy on Ovarian Reserve and Ovarian Function.
BACKGROUND
The effect of salpingectomy on ovarian reserve and ovarian function is still a controversial issue, and more investigations are needed.


OBJECTIVE
The aim of this study was to determine the effect of salpingectomy on ovarian reserve and ovarian function.
PubMed, Embase, Medline, Web of Knowledge, and the Cochrane trial register were searched.


METHODS
Studies must have similar study method and be published in English; clear data can be extracted from full test.


METHODS
Data were collected and analyzed by Review Manager 5.3.


RESULTS
A total of 13 studies were eligible. The level of anti-müllerian hormone is lower, and early follicular phase follicle-stimulating hormone is higher in salpingectomy groups. The level of early follicular phase estradiol and the ovarian volume of salpingectomy groups are the same as control. The total dose of follicle-stimulating hormone needed during in vitro fertilization and embryo transfer (IVF-ET) treatment cycles, the number of collected oocytes, and the clinical pregnancy rate are similar in salpingectomy and control groups.


CONCLUSIONS
Salpingectomy does not appear to affect ovarian function, ovarian response to gonadotropin stimulation, or outcome of IVF-ET in the short run. It may, however, impair ovarian reserve in the long run.
Associate Chief Physician, Department of Gynecology, OB/GYN Hospital, Shanghai Medical College, Fudan University, Shanghai and Department of OB/GYN, The Second People's Hospital of Ka-Shi, Xinjiang Uyghur Autonomous Region.
Feng
F
Qin
Resident Physician, Department of Gynecology, OB/GYN Hospital, Shanghai Medical College, Fudan University.
Dan-Feng
DF
Du
Associate Chief Physician, Department of Gynecology, OB/GYN Hospital, Shanghai Medical College, Fudan University, Shanghai and Shanghai Key Laboratory of Female Reproductive Endocrine-Related Diseases, Shanghai, China.
Xue-Lian
XL
Li
D054304:Anti-Mullerian Hormone / Q000097:blood; D005260:Female; D005307:Fertilization in Vitro; D005640:Follicle Stimulating Hormone / Q000097:blood; D006801:Humans; D007044:Hysterectomy; D010051:Ovarian Neoplasms / Q000517:prevention & control; D065851:Ovarian Reserve; D010053:Ovary / Q000502:physiology*; D011247:Pregnancy; D018873:Pregnancy Rate; D058994:Salpingectomy / Q000009:adverse effects
D054304:Anti-Mullerian Hormone; D005640:Follicle Stimulating Hormone