Genetic analysis of porcine circovirus type 2 from dead minks.
Circovirus infection is a growing problem in the field of veterinary and public health. It is associated with enteric diseases in both mammalian and avian hosts. In this study, we detected and isolated porcine circovirus strains in the tissue samples of minks that died from diarrhoea in Shandong Province, China. We sequenced the whole genome of two porcine strains of Circovirus, designated as MiSD-1 and MiSD-2， which had a 97.34% similarity on nucleotide sequence and were closely related to porcine circovirus type 2 (PCV2), but distantly related to mink circoviral species. Phylogenetically MiSD-1 and MiSD-2 are a part of the PCV2b genotype cluster, which is a highly prevalent genotype worldwide. The closer relationship of MiSD-1 and MiSD-2 to PCV2 from pigs than to other mink circoviral species may be evidence of cross-species transmission and considerable zoonotic potential.
School of Life Sciences, Shandong University, Jinan, PR China.|Shandong Provincial Center for Animal Disease Control and Prevention, Jinan, PR China.
Gui-Sheng
GS
Wang
Institute of Special Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, PR China.
Na
N
Sun
Shandong Provincial Center for Animal Disease Control and Prevention, Jinan, PR China.
Fu-Lin
FL
Tian
Institute of Special Economic Animals and Plants, Chinese Academy of Agricultural Sciences, Changchun, PR China.
Yong-Jun
YJ
Wen
Shandong Provincial Center for Animal Disease Control and Prevention, Jinan, PR China.
Cong
C
Xu
Shandong Key Laboratory of Animal Disease Control and Breeding, Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Sciences, Jinan, PR China.
Jun
J
Li
JL Te-yan Biological Technology Limited Liability Company, Changchun, PR China.
Qiang
Q
Chen
School of Life Sciences, Shandong University, Jinan, PR China.
Jin-Bao
JB
Wang
D000818:Animals; D002681:China; D017925:Circovirus / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D016000:Cluster Analysis; D016679:Genome, Viral; D008907:Mink / Q000821:virology*; D010802:Phylogeny; D012367:RNA, Viral / Q000235:genetics; D017422:Sequence Analysis, DNA; D017385:Sequence Homology
D012367:RNA, Viral