Neurofibromatosis, Down's syndrome, and acquired abnormalities.
We report a patient with Down's syndrome and neurofibromatosis who presented with a keloid, sebaceous cyst and acanthosis nigricans, along with dental and ophthalmological defects. The coexistence of neurofibromatosis type 1 and Down's syndrome which are two unrelated genetic conditions is itself a rarity.
Department of Dermatology and STD, Shadan Institute of Medical Sciences, Hyderabad, Telangana, India.
Syed Yousuf
SY
Ali
Departments of Dermatology and STD, Dr. VRK Women's Medical College, Teaching Hospital and Research Centre, Hyderabad, Telangana, India.
Vimala
V
Manne
Department of Orthodontics, Panineeya Institute of Dental Sciences and Research Centre, Hyderabad, Telangana, India.
Ranjit
R
Manne
Department of Dermatology and STD, Shadan Institute of Medical Sciences, Hyderabad, Telangana, India.
Chennamaneni
C
Himani
Acanthosis nigricans; Down's syndrome; keloid; myopia; neurofibromatosis; sebaceous cyst