New Glycoconjugates for the Treatment of Diseases Related to Metal Dyshomeostasis.
Metal dyshomeostasis is involved in several pathologies, making metal ions promising therapeutic targets. Conjugating 8-hydroxyquinolines with sugars gave rise to novel derivatives with improved solubility, selectivity, and multifunctionality. Biological evaluation of these compounds suggests they have potential as therapeutic agents in diseases related to metal dyshomeostasis.
Department of Chemical Sciences University of Catania viale A Doria 6 Catania 95125 Italy.
Valentina
V
Oliveri
antioxidants; cyclodextrin; glycoconjugates; metal complexes; metal dyshomeostasis