Paraneoplastic syndrome mimicking progressive supranuclear palsy.
Paraneoplastic syndrome presenting with progressive supranuclear palsy (PSP) phenotype is extremely rare. We report a patient who presented with features of rapidly progressive parkinsonism similar to PSP and was found to have small cell carcinoma of the lung along with seropositivity for onconeural antigen. The patient was treated with immunomodulation and was given chemotherapy for the malignancy and subsequently improved.
Department of Neurology, All India Institute of medical sciences, Ansari Nagar East, New Delhi, Delhi 110029, India.
Deepa
D
Dash
Department of Neurology, All India Institute of medical sciences, Ansari Nagar East, New Delhi, Delhi 110029, India.
Rima
R
Choudhary
Department of Neurology, All India Institute of medical sciences, Ansari Nagar East, New Delhi, Delhi 110029, India.
Bhargavi
B
Ramanujam
Department of Neurology, All India Institute of medical sciences, Ansari Nagar East, New Delhi, Delhi 110029, India.
Padma M
PM
Vasantha
Department of Neurology, All India Institute of medical sciences, Ansari Nagar East, New Delhi, Delhi 110029, India. Electronic address: manjari.tripathi1@gmail.com.
Manjari
M
Tripathi
D000368:Aged; D018288:Carcinoma, Small Cell / Q000175:diagnosis*; D003937:Diagnosis, Differential; D006801:Humans; D008175:Lung Neoplasms / Q000175:diagnosis*; D008297:Male; D010257:Paraneoplastic Syndromes / Q000175:diagnosis*; D020734:Parkinsonian Disorders / Q000175:diagnosis*; D010641:Phenotype; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis*
PSP; Paraneoplastic syndrome; Parkinson’s plus syndrome; Progressive supranuclear palsy