Bisphosphonate related osteonecrosis of calvarial bone.
BACKGROUND
A case of bisphosphonate related osteonecrosis of calvarial bone has not been reported.


METHODS
The clinical, imaging, and histopathological findings of the patient are presented. A 72-year-old female treated with bisphosphonates for osteoporosis presented with an open wound of her scalp. CT, MRI and bone scan suggested lytic and sclerotic changes with inflammation.


RESULTS
Surgical debridement was performed and final pathology was consistent with osteonecrosis and osteomyelitis.


CONCLUSIONS
This case illustrates that bisphosphonates can induce osteonecrosis of calvarial bone.
Grandview Medical Center, 405 West Grand Ave, Dayton, OH. Electronic address: jamescprueter@gmail.com.
James
J
Prueter
Kettering Head and Neck Surgery, Kettering Medical Center, 3737 Southern Blvd. Suite 2000, Kettering, OH. Electronic address: ambujakshan.dildeep@khnetwork.org.
Ambujakshan
A
Dildeep
D000368:Aged; D059266:Bisphosphonate-Associated Osteonecrosis of the Jaw / Q000175:diagnosis* / Q000209:etiology* / Q000601:surgery; D004164:Diphosphonates / Q000009:adverse effects*; D005260:Female; D006801:Humans; D010019:Osteomyelitis / Q000139:chemically induced* / Q000175:diagnosis* / Q000601:surgery; D010024:Osteoporosis / Q000188:drug therapy; D012886:Skull
D004164:Diphosphonates