Temporal Bone Mucormycosis.
METHODS
We present a case of temporal bone mucormycosis in a 71-year-old female with diabetes mellitus who presented to the emergency department with facial nerve paresis, otorrhea, and contralateral hemiparesis. After undergoing a tympanomastoidectomy, the patient's pathology exhibited fungal hyphae consistent with mucormycosis.


CONCLUSIONS
To our knowledge, there have been 9 reported cases of temporal bone mucormycosis, 3 of which presented with facial nerve paresis, all with some subsequent improvement. In this case, facial paralysis persisted at the time of last follow-up (2 months) despite surgery and intravenous antifungals. We also review and summarize the temporal bone mucormycosis literature.


CONCLUSIONS
Temporal bone mucormycosis is a rare and morbid infectious disease, though its outcomes appear to be different for patients who present with isolated temporal bone disease as compared to those individuals who develop temporal bone mucormycosis secondary to a rhinologic source.
Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Nicolas-George
NG
Katsantonis
Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA jacob.b.hunter@vanderbilt.edu.
Jacob B
JB
Hunter
Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Brendan P
BP
O'Connell
Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Jing
J
He
Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
James S
JS
Lewis
Department of Otolaryngology, Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
George B
GB
Wanna
D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging*; D048909:Diabetes Complications / Q000000981:diagnostic imaging / Q000276:immunology; D003920:Diabetes Mellitus; D005158:Facial Paralysis / Q000150:complications; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D020243:Infarction, Anterior Cerebral Artery / Q000150:complications / Q000000981:diagnostic imaging*; D020244:Infarction, Middle Cerebral Artery / Q000150:complications / Q000000981:diagnostic imaging*; D008416:Mastoid / Q000473:pathology / Q000601:surgery; D009091:Mucormycosis / Q000150:complications / Q000000981:diagnostic imaging* / Q000276:immunology / Q000601:surgery; D010033:Otitis Media / Q000150:complications / Q000000981:diagnostic imaging* / Q000276:immunology / Q000601:surgery; D013701:Temporal Bone / Q000000981:diagnostic imaging* / Q000601:surgery; D014057:Tomography, X-Ray Computed
facial nerve; infection; otitis media; temporal bone pathology