Centrosome amplification and cancer: Branching out.
Despite being a common feature of human cancer, the role of supernumerary centrosomes in tumourigenesis is still poorly understood. We have recently described a novel role for centrosome amplification in promoting cell invasion that could impact tumor progression.
Barts Cancer Institute; Queen Mary University of London ; Charterhouse Square ; London, UK.
Susana A
SA
Godinho
RAC1; cancer; centrosomes; invasion