Visible-Light-Induced Arylthiofluoroalkylations of Unactivated Heteroaromatics and Alkenes.
Visible-light-induced arylthiofluoroalkylations of unactivated heteroaromatics and alkenes have been developed utilizing readily available arylthiofluoroalkyl sources. This method enables simultaneous installation of sulfur and fluoroalkyl moieties, two important functional groups, which demonstrates its potential use for late-stage modifications in the synthesis of functional molecules. This method can be easily utilized to fine-tune the properties of lead molecules in drug development by controlling the number of fluorine atoms in the reagents.
Department of Chemistry, Chung-Ang University , 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
Yeojin
Y
Choi
Department of Bionanotechnology, Hanyang University , Ansan 15588, Republic of Korea.
Chunghyeon
C
Yu
Department of Chemistry & Nanoscience, Ewha Womans University , Seoul 03760, Republic of Korea.
Jun Soo
JS
Kim
Department of Chemistry, Chung-Ang University , 84 Heukseok-ro, Dongjak-gu, Seoul 06974, Republic of Korea.
Eun Jin
EJ
Cho