Ultrasound detection of knee joint degeneration in patients with multiple sclerosis.
OBJECTIVE
Early degeneration of the knees might occur in patients with multiple sclerosis secondary to balance and walking impairment and muscle weakness. The aims of this study were to evaluate the knee joints of patients with multiple sclerosis compared with healthy controls, using ultrasono-graphy, and to investigate whether there is any correlation between femoral cartilage degeneration and disease-related parameters.


METHODS
Study participants were 79 patients with multiple sclerosis and 60 healthy controls. The disease-related parameters, Expanded Disability Status Scale (EDSS), Western Ontario and McMaster Universities (WOMAC) osteoarthritis index, visual analogue scale (VAS) for pain severity, and Berg Balance Scale (BBS) scores were recorded. Femoral cartilage and knee effusion were evaluated using ultrasonography.


RESULTS
Femoral cartilages of patients with multiple sclerosis were more degenerated than those of healthy controls. Moreover, patients with multiple sclerosis had more effusion in their knees than did controls. In the multiple sclerosis group there was no correlation between cartilage degeneration grade, amount of effusion, and VAS-pain, BBS, WOMAC and EDSS scores.


CONCLUSIONS
Patients with multiple sclerosis may have more rapid degeneration of the knee cartilage and increased effusion compared with healthy controls. Ultrasonography is an effective method to detect these changes. However, cartilage degeneration was not found to be associated with disease-related parameters in multiple sclerosis.
Department of Physical Medicine and Rehabilitation, Faculty of Medicine, Afyon Kocatepe University, Afyonkarahisar, TR-03200, Turkey. seroglu79@gmail.com.
Selma
S
Eroglu
Esra Erkol
EE
Inal
Mehmet
M
Eroglu
Serdar
S
Oruc
Alper Murat
AM
Ulasli
Halime
H
Cevik
Seden
S
Demirci
Ozlem
O
Solak
Umit
U
Dundar
Hasan
H
Toktas
Mehmet
M
Yaman
D000328:Adult; D000368:Aged; D002356:Cartilage / Q000000981:diagnostic imaging / Q000473:pathology; D016022:Case-Control Studies; D005260:Female; D005269:Femur / Q000000981:diagnostic imaging; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009103:Multiple Sclerosis / Q000150:complications*; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging* / Q000209:etiology / Q000473:pathology; D010147:Pain Measurement; D012720:Severity of Illness Index; D014463:Ultrasonography