Probing Biological Sex Differences in Cancer.
A comprehensive analysis of data from The Cancer Genome Atlas has shed light on molecular-level differences between men and women with cancer. The study researchers separated 13 cancers into "strong" and "weak" sex-effect groups; cancers in the former showed extensive sex-biased molecular signatures, including changes in a considerable number of clinically actionable genes.
D018628:Gene Dosage; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics*; D012727:Sex Characteristics; D012737:Sex Factors