HIV-associated lymphocytic interstitial pneumonitis causes diffuse sestamibi lung uptake in myocardial perfusion imaging.
Technetium-99m ((99m)Tc) sestamibi myocardial perfusion scintigraphy (MPI) is widely used for the diagnosis and assessment of prognosis in patients with suspected coronary artery disease. During these investigations, inspection of raw projected data for the purpose of quality control may occasionally yield incidental noncardiac findings that suggest the presence of another primary noncardiac disease. We present a 66-year-old HIV patient with a tissue diagnosis of lymphoid interstitial pneumonitis (LIP), who demonstrated a diffuse increase of (99m)Tc sestamibi in bilateral lung fields both in rest and stress MPI.
Ramesh
R
Gadiraju
Srinivas
S
Bommireddipalli
Rajani
R
Rangray
E Gordon
EG
DePuey
CT, computed tomography; HRCT, high-resolution computed tomography; LIP, lymphoid interstitial pneumonitis; MPI, Technetium-99m sestamibi myocardial perfusion scintigraphy; MRI, magnetic resonance imaging; SPECT, single-photon-emission computed tomography