Shape of red blood cells in contact with artificial surfaces.
The phenomenon of physical contact between red blood cells and artificial surfaces is considered. A fully three-dimensional mathematical model of a bilayer membrane in contact with an artificial surface is presented. Numerical results for the different geometries and adhesion intensities are found to be in agreement with experimentally observed geometries obtained by means of digital holographic microscopy.
Department of Mathematics, Saarland University, Saarbrücken, Germany. richards@num.uni-sb.de.
Richards
http://orcid.org/0000-0002-4475-9284
R
Grzhibovskis
Department of Mathematics, Saarland University, Saarbrücken, Germany.
Elisabeth
E
Krämer
Laboratory of Biophysics, Saarland University, Saarbrücken, Germany.
Ingolf
I
Bernhardt
Biomedical Technology Center of the Medical Faculty, University of Münster, Münster, Germany.
Björn
B
Kemper
Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden.
Carl
C
Zanden
Department of Cryomorphology, Institute for Problems of Cryobiology and Cryomedicine, Kharkov, Ukraine.
Nikolay V
NV
Repin
Department of Physical and Biomedical Electronics, Kharkiv Polytechnic Institute, National Technical University, Kharkov, Ukraine.
Bogdan V
BV
Tkachuk
Department of Applied Physics, Chalmers University of Technology, Gothenburg, Sweden.
Marina V
MV
Voinova
D000818:Animals; D002448:Cell Adhesion; D048430:Cell Shape; D004912:Erythrocytes / Q000166:cytology*; D006801:Humans; D008051:Lipid Bilayers / Q000737:chemistry; D008962:Models, Theoretical; D013499:Surface Properties
D008051:Lipid Bilayers
Adhesion; Artificial surfaces; Helfrich functional; Red blood cells; Shape