MACULA RETINAL VASCULITIS AND CHOROIDITIS ASSOCIATED WITH GRANULOMATOSIS WITH POLYANGIITIS.
OBJECTIVE
To report a case series of two cases of granulomatosis with polyangiitis, previously known as Wegener granulomatosis, which developed macular necrosis, not previously associated with granulomatosis with polyangiitis, healed with fibrosis, despite aggressive immune-modulating therapy and good control of systemic disease.


METHODS
Case series of two cases with observation of treatment progress.


RESULTS
The results reported the progress of response to treatment in the two cases, which resulted in the final outcome of fibrosis in the macula region, despite being on aggressive immune-modulating therapy and good systemic control.


CONCLUSIONS
Granulomatosis with polyangiitis can be associated with macular necrosis leading to fibrosis, unresponsive to immune-modulating therapy.
*Ophthalmology Department, Royal Berkshire Hospital, Reading, United Kingdom; †Loyola Stritch School of Medicine, Maywood, Illinois; ‡University of Utah, Salt Lake City, Utah; §Indiana University School of Medicine, Indianapolis, Indiana; ¶Ophthalmology Department, Universiti Malaysia Sarawak (UNIMAS), Kota Samarahan, Sarawak, Malaysia.
Lik Thai
LT
Lim
Vinaya
V
Vasudevan
Julie
J
Shelton
Albert T
AT
Vitale
Ramana
R
Moorthy
D002833:Choroiditis / Q000209:etiology*; D005260:Female; D014890:Granulomatosis with Polyangiitis / Q000150:complications*; D006801:Humans; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D008875:Middle Aged; D009336:Necrosis / Q000473:pathology; D031300:Retinal Vasculitis / Q000209:etiology*