Detection of CMV DNA in the perilymph of a 6-year-old boy with congenital cytomegalovirus infection.
We present the case of a 6-year-old boy who received a cochlear implant for profound sensorineural hearing loss after being born with cytomegalovirus (CMV) infection. Even after 6 years, CMV DNA was still found in the perilymph of the cochlea. Our case shows that CMV DNA can be present in the cochlea years after congenital CMV infection, and it can explain why progressive and/or late-onset hearing loss occurs in these children.
Department of Otolaryngology-Head and Neck Surgery, Universitair Ziekenhuis Brussel, Laarbeeklaan 101, 1090 Brussels, Belgium. ina.foulon@uzbrussel.be.
Ina
I
Foulon
Oriane
O
Soetens
Leen
L
Vleurinck
Frans
F
Gordts
Astrid
A
Leus
Anne
A
Naessens
D002648:Child; D019929:Cochlear Implantation; D003587:Cytomegalovirus / Q000235:genetics*; D003586:Cytomegalovirus Infections / Q000150:complications / Q000151:congenital* / Q000378:metabolism; D004279:DNA, Viral / Q000378:metabolism*; D006312:Hearing Loss, Bilateral / Q000209:etiology / Q000601:surgery; D006319:Hearing Loss, Sensorineural / Q000209:etiology / Q000601:surgery; D006801:Humans; D008297:Male; D010498:Perilymph / Q000378:metabolism* / Q000821:virology
D004279:DNA, Viral