Role of Real-Time Elastography in the Evaluation of Cervical Lymph Nodes in Patients with Kikuchi Disease.
The purpose of this study was to compare the use of conventional ultrasound (US) and real-time elastography (RTE) in Kikuchi disease (KD, n = 48) and malignant cervical lymphadenopathy (n = 100) and to evaluate the role of RTE in patients suspected of having KD. In univariate analysis, conventional US revealed each benign feature more frequently in KD than in malignant lymphadenopathy (p < 0.05). However, a considerable number of cases (29, 60.4%) of KD were assessed as malignant with US. KD was assessed as benign by RTE more frequently than malignant lymphadenopathy (37 [77.1%] vs. 37 [37.0%], p < 0.001). In multivariate analysis, perinodal hyper-echogenicity was predictive of KD (odds ratio: 67.25, confidence interval: 10.95-413.04, p < 0.001). There was a tendency for KD to be assessed as malignant with conventional US, but benign with RTE. RTE can help to avoid unnecessary biopsy in patients suspected of having KD on the basis of conventional US.
Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea.
Jiyeon
J
Baik
Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea; Department of Radiology, Newoori Namsan Hospital, Busan, Korea. Electronic address: lkh770429@naver.com.
Kwang Hwi
KH
Lee
Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea.
JiHwa
J
Ryu
Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea.
OkHwa
O
Kim
Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea.
Jung-Hee
JH
Yoon
Department of Radiology, Inje University College of Medicine, Haeundae Paik Hospital, Busan, Korea.
Seung Ho
SH
Kim
Department of Radiology, Gyeongsang National University School of Medicine, Gyeongsang National University Changwon Hospital, Changwon, Korea.
Hye Jin
HJ
Baek
D000328:Adult; D054459:Elasticity Imaging Techniques / Q000379:methods*; D005260:Female; D020042:Histiocytic Necrotizing Lymphadenitis / Q000000981:diagnostic imaging*; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D009333:Neck; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014463:Ultrasonography / Q000379:methods
Kikuchi disease; Malignant lymphadenopathy; Real-time elastography; Ultrasound