C REACTIVE PROTEIN LEVELS AS A MARKER OF CORONARY HEART DISEASE IN MIDDLE AGED INDIVIDUALS.
BACKGROUND
coronary heart disease is multifactorial inflammatory process which involves the accumulation of lipid macrophages and intimal plaques in smooth muscle cell in large and medium sized arteries. C reactive protein (CRP) which is an inflammatory marker is considered as global risk assessment for coronary heart disease. The objective of study is to determine the CRP level as risk marker in coronary heart disease in middle aged individuals.


METHODS
This cross sectional study was conducted in Hayatabad medical complex Peshawar and Rehman Medical Institute Peshawar. On the basis of predesigned questionnaire, 100 middle aged individuals of age 40-60 years and 50 normal subjects of same age were questioned by taking consent. Data was collected and analysed by SPSS-15.


RESULTS
It was founded that 74% of patients have higher values of CRP and 4% have high values of CRP in controls. The t-test applied at 95% confidence interval with mean difference of 22.096 + 2.36 of CHD individuals and 1.288 ± 1.70 of control group. P-value was 0.001 which is found to be significant.


CONCLUSIONS
It was observed that CRP has higher association with CHD.
Nadia
N
Haleem
Irfan Zahid
IZ
Marwat
Shazia
S
Tauqeer
Sarwat
S
Abbasi
D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D016022:Case-Control Studies; D003324:Coronary Artery Disease / Q000097:blood* / Q000175:diagnosis; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors
D015415:Biomarkers; D002097:C-Reactive Protein