Ankle-Brachial Index and Long-Term (10 Years) Survival of Nondiabetic Hemodialysis Patients.
Low (<0.9) and high (>1.4) ankle brachial index (ABI) is associated with a higher cardiovascular (CV) mortality in the general and hemodialysis (HD) population. The aim of our study was to determine the impact of ABI on long-term survival of 52 non-diabetic HD patients. The ABI was determined using an automated, non-invasive waveform analysis device. Patients were divided into three groups: low (<0.9), normal (0.9-1.4) and high (>1.4) ABI. Patients were observed from the date of ABI measurement until their death or ten years. Survival analysis showed higher risk for CV death in HD patients with high ABI compared to normal ABI (log rank test P < 0.027). In Cox regression model adjusted for arterial hypertension, smoking, serum cholesterol and triglycerides, high ABI (P < 0.049) remained a predictor of mortality. The results indicate an association between ABI and long-term survival of non-diabetic HD patients and only high ABI was associated with higher CV mortality.
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Sebastjan
S
Bevc
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Darinka
D
Purg
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Maša
M
Knehtl
Department of Dialysis, University Medical Centre Maribor, Maribor, Slovenia.
Martin
M
Hren
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Nina
N
Turnšek
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Nina
N
Hojs
Department of Dialysis, University Medical Centre Maribor, Maribor, Slovenia.
Tadej
T
Zorman
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Benjamin
B
Dvoršak
Department of Dialysis, University Medical Centre Maribor, Maribor, Slovenia.
Robert
R
Ekart
Clinic for Internal Medicine, Department of Nephrology, University Medical Centre Maribor, Maribor, Slovenia.
Radovan
R
Hojs
D000328:Adult; D000368:Aged; D055109:Ankle Brachial Index; D002318:Cardiovascular Diseases / Q000401:mortality*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D016016:Proportional Hazards Models; D006435:Renal Dialysis / Q000379:methods* / Q000401:mortality; D016019:Survival Analysis; D015996:Survival Rate; D013997:Time Factors; D055815:Young Adult
Ankle-brachial index; Long-term cardiovascular mortality; Nondiabetic hemodialysis patients