Symmetric BMPs on the Developmental Road.
The signaling pathways and cellular mechanisms that achieve alignment of dorsal and ventral midline structures remain a poorly understood aspect of vertebrate development. In this issue of Developmental Cell, Arraf et al. (2016) find a requisite role for bilaterally symmetrical BMP signaling in coordinating dorsal and ventral tissue morphogenesis.
Developmental Biology Program, Sloan-Kettering Institute, New York, NY 10065, USA.
Svetlana
S
Gavrilov
Developmental Biology Program, Sloan-Kettering Institute, New York, NY 10065, USA. Electronic address: e-lacy@mskcc.org.
Elizabeth
E
Lacy
D000818:Animals; D019485:Bone Morphogenetic Proteins / Q000378:metabolism*; D002642:Chick Embryo; D002645:Chickens; D048788:Growth and Development; D008954:Models, Biological; D009024:Morphogenesis; D015398:Signal Transduction
D019485:Bone Morphogenetic Proteins