A novel HLA-B*40 allele, B*40:01:40, identified in a Chinese individual.
A new allele, officially named B*40:01:40, was detected in a Chinese individual by sequence-based typing (SBT). The new allele differs from B*40:01:01 by a single nucleotide exchange at position 99 in codon 9, which results in synonymous substitution and seems not to compromise the HLA complex and T-cell receptor interaction.
Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning, China.
Y F
YF
Pei
Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning, China.
H N
HN
Huang
Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning, China.
H C
HC
Li
Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning, China.
W D
WD
Shen
D000483:Alleles; D019943:Amino Acid Substitution / Q000235:genetics / Q000276:immunology; D044466:Asian People; D002681:China; D003062:Codon / Q000235:genetics; D015235:HLA-B Antigens / Q000235:genetics* / Q000276:immunology* / Q000302:isolation & purification; D006801:Humans; D011948:Receptors, Antigen, T-Cell / Q000235:genetics / Q000276:immunology
D003062:Codon; D015235:HLA-B Antigens; D011948:Receptors, Antigen, T-Cell