Minimally invasive extracorporeal circulation improves quality of life after coronary artery bypass grafting.
OBJECTIVE
The effect on postoperative health-related quality of life (HRQoL) after coronary artery bypass grafting (CABG) surgery with conventional cardiopulmonary bypass (cCPB) and off-pump surgery has been investigated extensively; however, there are no studies focusing on HRQoL after surgery with minimally invasive extracorporeal circulation (MiECC). Therefore, we sought to prospectively investigate the effect of MiECC on postoperative HRQoL when compared with cCPB in patients undergoing CABG over a short-term (3-month) follow-up period.


METHODS
Sixty patients scheduled for elective CABG surgery were randomly assigned into two groups: those who had surgery on MiECC system (n = 30) and those who underwent CABG using cCPB (n = 30). Quality-of-life assessment was performed preoperatively (baseline-T0), at first postoperative month (T1) and at 3-month follow-up (T3). The RAND SF-36 scale was used for data collection, which included both sociodemographic and clinical characteristics of patients. The primary outcome of the study was quantitative measurement of postoperative HRQoL at 3-month follow-up.


RESULTS
Both groups were balanced in terms of demographic, socio-economic and operative characteristics. At 3-month follow-up, mean SF-36 component and summary scores in each group were higher in absolute values than the respective mean baseline scores, apart from role-physical score in patients operated with cCPB. Patients operated on MiECC showed uniformly significantly higher values in all individual and summary domains, whereas patients operated on cCPB showed significant improvement in 6/8 individual domains. Patients operated on MiECC showed a more pronounced increase in SF-36 individual domain scores from the first to the third postoperative month when compared with cCPB, which was statistically significant regarding physical functioning (P = 0.001), role-physical (P < 0.001), vitality (P = 0.01) and role-emotional (P = 0.004). This resulted in a significant improvement in physical (P = 0.002) and mental (P = 0.01) summary scores.


CONCLUSIONS
The current study proves that MiECC significantly improves HRQoL after coronary surgery compared with cCPB. This finding, combined with results from large-scale studies showing superior clinical outcomes from its use, enhances the role of MiECC as a dominant technique in coronary revascularization surgery.
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
Kyriakos
K
Anastasiadis
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece antonits@auth.gr antonits@otenet.gr.
Polychronis
P
Antonitsis
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
Georgia
G
Kostarellou
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
Athanassios
A
Kleontas
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
Apostolos
A
Deliopoulos
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
Vassilios
V
Grosomanidis
Cardiothoracic Department, AHEPA University Hospital, Thessaloniki, Greece.
Helena
H
Argiriadou
D000368:Aged; D002315:Cardiopulmonary Bypass / Q000009:adverse effects / Q000379:methods; D001026:Coronary Artery Bypass / Q000009:adverse effects / Q000379:methods*; D005112:Extracorporeal Circulation / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D011788:Quality of Life; D011795:Surveys and Questionnaires
Cardiopulmonary bypass; Coronary artery bypass grafting; Minimally invasive extracorporeal circulation; Quality of life