Stitching Organelles: Organization and Function of Specialized Membrane Contact Sites in Plants.
The coordination of multiple metabolic activities in plants relies on an interorganelle communication network established through membrane contact sites (MCS). The MCS are maintained in transient or durable configurations by tethering structures which keep the two membranes in close proximity, and create chemical microdomains that allow localized and targeted exchange of small molecules and possibly proteins. The past few years have witnessed a dramatic increase in our understanding of the structural and molecular organization of plant interorganelle MCS, and their crucial roles in plant specialized functions including stress responses, cell to cell communication, and lipid transport. In this review we summarize recent advances in understanding the molecular components, structural organization, and functions of different plant-specific MCS architectures.
Instituto de Hortofruticultura Subtropical y Mediterránea, Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Biología Molecular y Bioquímica, Universidad de Málaga, 29071 Malaga, Spain; Department of Botany, Faculty of Science, University of British Columbia, Vancouver V6T 1Z4, Canada.
Jessica
J
Pérez-Sancho
Biomedical Sciences Research Complex, University of St Andrews, BMS Building, North Haugh, St Andrews, Fife KY16 9ST, UK; Cell and Molecular Sciences, The James Hutton Institute, Invergowrie, Dundee DD2 5DA, UK.
Jens
J
Tilsner
Department of Botany, Faculty of Science, University of British Columbia, Vancouver V6T 1Z4, Canada.
A Lacey
AL
Samuels
Instituto de Hortofruticultura Subtropical y Mediterránea, Universidad de Málaga-Consejo Superior de Investigaciones Científicas, Departamento de Biología Molecular y Bioquímica, Universidad de Málaga, 29071 Malaga, Spain.
Miguel A
MA
Botella
Laboratory of Membrane Biogenesis (LBM), Centre National de la Recherche Scientifique (CNRS) Unité Mixte de Recherche 5200, University of Bordeaux, 71 Avenue Edouard Bourlaux, 33883 Villenave d'Ornon CEDEX, France.
Emmanuelle M
EM
Bayer
Department of Botany, Faculty of Science, University of British Columbia, Vancouver V6T 1Z4, Canada. Electronic address: abel.rosado@botany.ubc.ca.
Abel
A
Rosado
D005075:Biological Evolution; D002462:Cell Membrane / Q000378:metabolism*; D005057:Eukaryotic Cells / Q000378:metabolism; D008055:Lipids / Q000737:chemistry; D015388:Organelles / Q000378:metabolism*; D010944:Plants / Q000378:metabolism*
D008055:Lipids
PLAMs; SYT; VAP27; plasmodesmata; stress-inducible MCS; tethers