A novel imaging platform for non-invasive screening of abnormal glucose tolerance.
Optical measurement of skin auto-fluorescence (SAF), most likely emanating from accumulated advanced glycation end-products (AGEs), has been proposed for the noninvasive diagnosis of glucose intolerance in clinical settings. Here, we developed a novel imaging system with transmission geometry for SAF measurement and compared its diagnostic performance in a Korean population.
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea.
Bosu
B
Jeong
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Chang Hee
CH
Jung
Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Diabetes Center, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.
Yong-Ho
YH
Lee
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea.
Il-Hyung
IH
Shin
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea.
Hansuk
H
Kim
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea.
Soo-Jin
SJ
Bae
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea.
Dae-Sic
DS
Lee
Division of Endocrinology and Metabolism, Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; Diabetes Center, Severance Hospital, Yonsei University Health System, Seoul, Republic of Korea.
Eun Seok
ES
Kang
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea.
Uk
U
Kang
Russia Science Seoul Center, Advanced Medical Device Research Division, Korea Electrotechnology Research Institute, Seoul, Republic of Korea. Electronic address: jongjin_kim@keri.re.kr.
Jong Jin
JJ
Kim
Department of Internal Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address: jypark@amc.seoul.kr.
Joong-Yeol
JY
Park
D000328:Adult; D000368:Aged; D005260:Female; D018149:Glucose Intolerance / Q000000981:diagnostic imaging*; D017127:Glycation End Products, Advanced / Q000378:metabolism; D006801:Humans; D006943:Hyperglycemia / Q000000981:diagnostic imaging*; D008297:Male; D008403:Mass Screening / Q000379:methods; D008875:Middle Aged; D061848:Optical Imaging / Q000379:methods*; D012680:Sensitivity and Specificity; D012867:Skin / Q000378:metabolism*; D013050:Spectrometry, Fluorescence / Q000379:methods*
D017127:Glycation End Products, Advanced
AGE; Diagnosis; Glucose intolerance; Noninvasive; Skin auto-fluorescence