Monocyte to high-density lipoprotein cholesterol ratio is predictive of in-hospital and five-year mortality in ST-segment elevation myocardial infarction.
BACKGROUND
We assessed the value of monocyte to high-density lipoprotein cholesterol ratio (MHR) in predicting in-hospital and 5-year mortality and major adverse cardiovascular events (MACE) in ST-segment elevation myocardial infarction (STEMI) patients.


METHODS
A group of 1,598 patients were enrolled and divided into tertiles according to MHR values. The effects of different variables on clinical outcomes were assessed by Cox regression analysis.


RESULTS
MHR was found as an independent predictor of in-hospital mortality (HR = 3.745, 95% CI 1.308-5.950), in-hospital MACE (HR 1.501, 95% CI 1.015-1.993, p = 0.022) and 5-year mortality (HR = 2.048, 95% CI 1.225-4.091, p = 0.014) and 5-year MACE (HR 1.285, 95% CI 1.064-1.552, p = 0.009).


CONCLUSIONS
MHR is an independent predictor of in-hospital and long term mortality and MACE in STEMI.
Department of Cardiology, Turkiye Yuksek Ihtisas Education and R esearch Hospital, Ankara, Turkey. drskad@gmail.com.
Sadık Kadri
SK
Açıkgöz
Eser
E
Açıkgöz
Barış
B
Şensoy
Salih
S
Topal
Sinan
S
Aydoğdu
D000328:Adult; D015415:Biomarkers / Q000097:blood; D008076:Cholesterol, HDL / Q000097:blood*; D017023:Coronary Angiography; D004562:Electrocardiography; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality / Q000639:trends; D006801:Humans; D008297:Male; D008875:Middle Aged; D009000:Monocytes / Q000473:pathology*; D012189:Retrospective Studies; D012307:Risk Factors; D000072657:ST Elevation Myocardial Infarction / Q000097:blood* / Q000175:diagnosis / Q000401:mortality; D015996:Survival Rate / Q000639:trends; D013997:Time Factors; D014421:Turkey / Q000453:epidemiology
D015415:Biomarkers; D008076:Cholesterol, HDL
ST-segment elevation myocardial infarction; high density lipoprotein cholesterol; monocyte; monocyte to high-density lipoprotein ratio