Tuning O2 Reactivity through Synergistic Photo/Copper Catalysis: Direct Synthesis of 4-Aryl tetralones via Cyclodimerization-Oxygenation of Styrenes.
A transformation is presented that enables chemists to construct 4-aryl tetralones via visible-light-induced cyclodimerization-oxygenation of styrene under very mild conditions. Adding a catalytic amount of CuOAc obviously improves the yield. A mechanistic study reveals that the photoredox catalyst played the role of activating O2 while Cu affected the reactivity of reactive oxygen species (ROS).
College of Chemistry and Molecular Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, Hubei, 430072, P. R. China.
Xu
X
Zhang
College of Chemistry and Molecular Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, Hubei, 430072, P. R. China.
Hong
H
Yi
College of Chemistry and Molecular Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, Hubei, 430072, P. R. China.
Yi
Y
Luo
College of Chemistry and Molecular Sciences, Institute for Advanced Studies, Wuhan University, Wuhan, Hubei, 430072, P. R. China. aiwenlei@whu.edu.cn.|National Research Center for Carbohydrate Synthesis, Jiangxi Normal University, Nanchang, 330022, Jiangxi, P. R. China. aiwenlei@whu.edu.cn.
Aiwen
http://orcid.org/0000-0001-8417-3061
A
Lei
O2 activation; copper catalysis; photoredox catalysis; superoxide radical anion