Association between pregnancy and adnexal torsion: A population-based, matched case-control study.
The purpose of this study was to determine the effect of pregnancy on adnexal torsion (AT). We conducted a matched case-control study using the Korean Health Insurance Review and Assessment Service-National Inpatients Sample (HIRA-NIS) from 2009 to 2011. AT patients were defined as women with both a diagnostic code (N835) and a surgical code for AT. The AT patients were randomly matched 1:4 with women without AT by age and year of claim. In total, 545 AT cases and 2180 controls were enrolled from a total of 1,843,451 women. After adjustment for such covariates as age, pregnancy was found to be associated with a lower rate of AT (adjusted odds ratio 0.314, 95% confidence interval [CI] 0.237-0.416, P value <0.01) and ovarian hyperstimulation syndrome was associated with a higher rate of AT (adjusted odds ratio 20.091, 95% CI 3.607-111.908, P value <0.01). We found that pregnancy is a negative risk factor for AT. However, a further study is needed to elucidate the mechanisms underlying these results.
Department of Obstetrics and Gynaecology, School of Medicine, Eulji University, Daejeon Department of Obstetrics and Gynaecology, MizMedi Hospital, Seoul Department of Preventive Medicine, School of Medicine, Eulji University, Daejeon, Korea Department of Obstetrics and Gynecology, Hankang Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea Department of Obstetrics and Gynecology, Gyeongsang National University Changwon Hospital, Gyeongsang National University, School of Medicine, Changwon, Republic of Korea.
Jin-Sung
JS
Yuk
Ji-Yeon
JY
Shin
Won I
WI
Park
Dae Woon
DW
Kim
Jung Whan
JW
Shin
Jung Hun
JH
Lee
D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D016017:Odds Ratio; D010049:Ovarian Diseases / Q000175:diagnosis / Q000453:epidemiology*; D011159:Population Surveillance; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000453:epidemiology*; D011256:Pregnancy Outcome; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D014102:Torsion Abnormality / Q000175:diagnosis / Q000453:epidemiology*