Anthropometric measurements for the prediction of the metabolic syndrome: a cross-sectional study on adolescents and young adults from southern india.
OBJECTIVE
To determine which anthropometric measurement correlates best with the metabolic abnormalities associated with the metabolic syndrome in adolescents and young adults.


METHODS
Cross-sectional study.


METHODS
Schools, high schools and universities.


METHODS
1359 adolescents and young adults aged 14-25 years.


METHODS
Anthropometric predictors of metabolic abnormalities as classified by International Diabetes Federation definition.


RESULTS
The waist circumference (OR 1.56, 95% CI 1.0 to 2.43: p≤0.01) and the abdominal skin fold thickness (OR 1.44, 95% CI 1.02 to 2.04, p≤0.01) above the third quintile cut-offs were found to be significantly associated with metabolic abnormalities. The sensitivity of either one of these measurements in predicting metabolic abnormalities was 66.1% with a negative predictive value of 82.8%. Hyperglycaemia was significantly associated with an abdominal skin fold thickness over the fourth quintile alone (OR 1.63, 95% CI 1.24 to 2.1). All the anthropometric measurements correlated well with elevated triglycerides and hypertension.


CONCLUSIONS
In a large community-based cross-sectional survey of subjects aged 14-25 years, the waist circumference and the abdominal skin fold thickness are important predictors of the metabolic abnormalities associated with metabolic syndrome. This simple clinical tool may help in a primary care setting to identify subjects who require a further biochemical evaluation and would considerably reduce the cost of unwarranted testing.
Department of Endocrinology, Diabetes & Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India; Department of Molecular Medicine & Surgery, Karolinska INSTITUTET, Stockholm, Sweden.
S K
SK
Vasan
Department of Endocrinology, Diabetes & Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India.
N
N
Thomas
Department of Biostatistics, Christian Medical College, Vellore, Tamil Nadu, India.
S
S
Christopher
Department of Clinical Biochemistry, Christian Medical College & Hospital, Vellore, Tamil Nadu, India.
F S
FS
Geethanjali
Department of Endocrinology, Diabetes & Metabolism, Christian Medical College & Hospital, Vellore, Tamil Nadu, India.
T V
TV
Paul
Department of Molecular Medicine & Surgery, Karolinska INSTITUTET, Stockholm, Sweden.
C B
CB
Sanjeevi
Metabolic syndrome; adolescents; anthropometry; skin fold thickness; waist circumference