Sensitivity of cutometer data to stratum corneum hydration level: A preliminary study.
OBJECTIVE
The cutometer is an instrument that measures mechanical properties of skin. The NOVA dermal phase meter (DPM) measures the stratum corneum (SC) hydration level. The objectives of this study were to determine which parameters of the cutometer data curves were most sensitive to changes in SC hydration level, and to determine if lowering the skin stress applied by the cutometer would increase the instrument's sensitivity to SC hydration.


METHODS
In two studies, the volar forearms of ten and six subjects, respectively, were hydrated with wet paper towels for ten min. Measurements were made with the cutometer at various vacuum levels, and with the DPM. In another study, leg skin of nine subjects was hydrated by applying moisturizing lotions for 2 weeks. Measurements were made with the cutometer and DPM.


CONCLUSIONS
Significant changes in DPM and cutometer measurements were found after hydrating skin in each study. However, only three correlations were found between cutometer data and DPM data. The lack of correlation was perhaps due to the differences in the depth into the skin which the two instruments measure. It is not clear which cutometer data parameters are generally most sensitive to hydration level, since different parameters were found to be most sensitive in each of the three studies. Finally, lowering the cutometer vacuum level generally did not increase the sensitivity of the measurements to changes in hydration levels.
University of Cincinnati College of Phamacy, Cincinnati, Ohio, USA.
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BC
Murray
University of Cincinnati College of Phamacy, Cincinnati, Ohio, USA.
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Wickett
NOVA meter; bioengineering; cutometer; dermal phase meter; dermal torque meter