A review of setup error in supine breast radiotherapy using cone-beam computed tomography.
Setup error in breast radiotherapy (RT) measured with 3-dimensional cone-beam computed tomography (CBCT) is becoming more common. The purpose of this study is to review the literature relating to the magnitude of setup error in breast RT measured with CBCT. The different methods of image registration between CBCT and planning computed tomography (CT) scan were also explored. A literature search, not limited by date, was conducted using Medline and Google Scholar with the following key words: breast cancer, RT, setup error, and CBCT. This review includes studies that reported on systematic and random errors, and the methods used when registering CBCT scans with planning CT scan. A total of 11 relevant studies were identified for inclusion in this review. The average magnitude of error is generally less than 5mm across a number of studies reviewed. The common registration methods used when registering CBCT scans with planning CT scan are based on bony anatomy, soft tissue, and surgical clips. No clear relationships between the setup errors detected and methods of registration were observed from this review. Further studies are needed to assess the benefit of CBCT over electronic portal image, as CBCT remains unproven to be of wide benefit in breast RT.
South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia; Liverpool and Macarthur Cancer Therapy Centres, New South Wales, Australia; Ingham Institute of Applied Medical Research, Sydney, New South Wales, Australia. Electronic address: Vikneswary.batumalai@sswahs.nsw.gov.au.
Vikneswary
V
Batumalai
South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia; Liverpool and Macarthur Cancer Therapy Centres, New South Wales, Australia; Ingham Institute of Applied Medical Research, Sydney, New South Wales, Australia; Centre for Medical Radiation Physics, University of Wollongong, Wollongong, New South Wales, Australia; Institute of Medical Physics, School of Physics, University of Sydney, Sydney, New South Wales, Australia.
Lois
L
Holloway
South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia; Liverpool and Macarthur Cancer Therapy Centres, New South Wales, Australia; Ingham Institute of Applied Medical Research, Sydney, New South Wales, Australia.
Geoff P
GP
Delaney
D001943:Breast Neoplasms / Q000532:radiotherapy*; D054893:Cone-Beam Computed Tomography / Q000379:methods*; D005260:Female; D006801:Humans; D056888:Patient Positioning; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods; D061106:Radiotherapy Setup Errors; D061089:Radiotherapy, Image-Guided / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated; D016683:Supine Position
Breast cancer; Cone-beam computed tomography (CBCT); Radiotherapy; Review; Setup errors