Distribution and estrogenic potential of endocrine disrupting chemicals (EDCs) in estuarine sediments from Mumbai, India.
Endocrine disrupting chemicals (EDCs) are responsible for inappropriate development and they alter the hormonal and homeostatic systems of organism. Phthalates (PAEs), bisphenol A (BPA) and other EDCs were monitored in surface sediments at different stations across Thane Creek, India. Analysis of PAEs was carried out using GC-MS technique, while BPA and other EDCs were analyzing on UPLC-PDA instrument. Di-n-butyl phthalate (DBP) had the highest concentration among all fourteen analyzed phthalates ranges between 0.13 and 0.4 mg kg(-1); and was detectable in all sediment samples. Strong correlation (r = 0.95, p < 0.01) was observed between total organic carbon (TOC, %) and total PAEs. BPA was also detected in all samples; average BPA concentration varies from 16.3 to 35.79 μg kg(-1) with mean value 25.15 μg kg(-1) dry weight of sediment. Synthetic EDCs such as 4-para-nonylphenol (NP) and 4-tert-octylphenol (OP) were also analyzed; and their average concentrations were founds to be 356.5 and 176 μg kg(-1), respectively. Estrone (E1), 17β-estradiol (E2), and 17α-ethinylestradiol (EE2) were the main contributors to the overall estradiol equivalent concentration (EEQs) in sediment, their average total percentage contributions is more than 90 %.
Environmental Monitoring and Assessment Section, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, 400085, India.
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M
Tiwari
Environmental Monitoring and Assessment Section, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, 400085, India.
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SK
Sahu
Environmental Monitoring and Assessment Section, Health Safety and Environment Group, Bhabha Atomic Research Centre, Mumbai, 400085, India. ggp@barc.gov.in.
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GG
Pandit
D001559:Benzhydryl Compounds / Q000032:analysis; D003993:Dibutyl Phthalate / Q000032:analysis; D052244:Endocrine Disruptors / Q000032:analysis*; D004784:Environmental Monitoring; D004958:Estradiol / Q000032:analysis; D004970:Estrone / Q000032:analysis; D063366:Estuaries; D004997:Ethinyl Estradiol / Q000032:analysis; D008401:Gas Chromatography-Mass Spectrometry; D007194:India; D010636:Phenols / Q000032:analysis; D014874:Water Pollutants, Chemical / Q000032:analysis*; D000098826:Bisphenol A Compounds
D001559:Benzhydryl Compounds; D003993:Dibutyl Phthalate; D052244:Endocrine Disruptors; D004958:Estradiol; D004970:Estrone; D004997:Ethinyl Estradiol; D010636:Phenols; D014874:Water Pollutants, Chemical; C025256:nonylphenol; C041594:4-nonylphenol; C105260:4-tert-octylphenol; C006780:bisphenol A; D000098826:Bisphenol A Compounds
BPA; EDCs; Estrogenic potential; GC–MS; Phthalates; Sediment