Ocular Adnexal Lymphoma Presenting as Refractory Unilateral Open-angle Glaucoma.
We report a single case of masquerade glaucoma caused by increased episcleral venous pressure from adnexal lymphoma. The patient presented as a referral for unilateral glaucoma with intraocular pressures (IOPs) consistently >40 mm Hg (right eye). We present data conclusively demonstrating extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue in the involved eye, and provide an account of the treatment of the tumor with sustained regression and complete resolution of his elevated IOP. We conclude with a discussion of the proposed mechanism. This case serves as a reminder that unilateral open-angle glaucoma can be a sign of indolent ocular adnexal lymphoma. The case also provides a useful model for increased IOP with orbital lesions.
Cole Eye Institute, Cleveland Clinic Foundation, Cleveland, OH.
Nathaniel C
NC
Sears
Annapurna
A
Singh
Arun D
AD
Singh
D000368:Aged; D001706:Biopsy; D003228:Conjunctiva / Q000473:pathology; D003230:Conjunctival Neoplasms / Q000150:complications* / Q000175:diagnosis; D003937:Diagnosis, Differential; D005451:Fluorescein Angiography; D005654:Fundus Oculi; D005902:Glaucoma, Open-Angle / Q000175:diagnosis / Q000209:etiology* / Q000503:physiopathology; D006801:Humans; D007429:Intraocular Pressure; D018442:Lymphoma, B-Cell, Marginal Zone / Q000150:complications* / Q000175:diagnosis; D008297:Male; D014463:Ultrasonography