Choroidal changes observed with enhanced depth imaging optical coherence tomography in patients with mild Graves orbitopathy.
PurposeTo evaluate the choroidal thickness in patients with Graves orbitopathy (GO) using enhanced depth imaging-optical coherence tomography (EDI-OCT).MethodsThirty-one patients with GO were evaluated prospectively. All subjects underwent ophthalmologic examination including best-corrected visual acuity, intraocular pressure measurement, biomicroscopic, and fundus examination. Choroidal thickness was measured at the central fovea. In addition, visual evoked potential measurement and visual field evaluation were performed.ResultsThe mean choroidal thickness was 377.8±7.4 μ in the GO group, and 334±13.7 μ in the control group. (P=0.004). There was a strong correlation between the choridal thickness and the clinical activity scores (CAS) of the patients (r=0.281, P=0.027). Additionally, there was a correlation between the choroidal thickness and the visual-evoked potential (VEP) P100 latency measurements of the patients (r=0.439, P=0.001).ConclusionsThe results of this study demonstrate that choroid is thicker in patients with GO. The choroidal thickness is also correlated with the CAS and VEP P100 latency measurements in these patients.
Faculty of Medicine, Ophthalmology Department, Kocaeli University, Kocaeli, Turkey.
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Özkan
Faculty of Medicine, Ophthalmology Department, Kocaeli University, Kocaeli, Turkey.
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ÇA
Koçer
Faculty of Medicine, Ophthalmology Department, Kocaeli University, Kocaeli, Turkey.
Ö
Ö
Altintaş
Faculty of Medicine, Ophthalmology Department, Kocaeli University, Kocaeli, Turkey.
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L
Karabaş
Ophthalmology Department, Şişli Etfal Training and Reseach Hospital, Istanbul, Turkey.
A Z
AZ
Acar
Faculty of Medicine, Ophthalmology Department, Kocaeli University, Kocaeli, Turkey.
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Yüksel
D000328:Adult; D002829:Choroid / Q000000981:diagnostic imaging / Q000473:pathology*; D005074:Evoked Potentials, Visual / Q000502:physiology; D005260:Female; D049970:Graves Ophthalmopathy / Q000150:complications* / Q000175:diagnosis; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011446:Prospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology