[EXPERIMENTAL POSTTERIOIDEKTOMIC FATTY LIVER DISEASE IN RATS].
The aim was to investigate the morphological features of the liver in animals at different periods of post-operative hypothyroidism to reproduce the experimental fatty liver disease.


METHODS
thyroidectomy was performed 20 laboratory rats, females breed nonlinear, thyroid was mobilized without thyroid thyroidectomy to 10 individuals. The morphological pattern of the rat's liver was studied in terms of 4 and 8 weeks after surgery at the light optical level.


RESULTS
4 weeks after thyroidectomy was found in rat liver protein and fatty degeneration with focal of inflammatory infiltration, against the backdrop of a serous edema. On the 8th week of the experiment observed the progression of degenerative, necroinflammatory processes expressed hydropic dystrophy, atomizing steatosis and the appearance of periportal fibrosis.
G S
GS
Dzhulay
S V
SV
Shchelochenkov
M B
MB
Petrova
A A
AA
Bibikova
D000818:Animals; D004195:Disease Models, Animal; D005234:Fatty Liver / Q000209:etiology* / Q000378:metabolism / Q000473:pathology; D005260:Female; D007037:Hypothyroidism / Q000150:complications* / Q000378:metabolism; D051381:Rats; D013961:Thyroid Gland / Q000378:metabolism / Q000601:surgery*; D013965:Thyroidectomy