Obstetrics and perinatal outcomes of dichorionic twin pregnancy following ART compared with spontaneous pregnancy.
BACKGROUND
Regarding to the recent advances in assisted reproductive techniques (ART), twin and multiple pregnancies have increased during past years.


OBJECTIVE
This study was performed to compare obstetrics and perinatal outcomes of dichorionic twin pregnancy following ART with spontaneous pregnancy.


METHODS
In this cross-sectional study which was performed in Ghaem Hospital, Mashhad University of Medical Sciences, 107 dichorionic twin pregnancy were enrolled in two groups: spontaneous group (n=96) and ART group (n=31). Basic criteria and obstetrics and neonatal outcomes information including demographic data, gestational age, mode of delivery, pregnancy complications (preeclampsia, gestational diabetes, preterm labor, and intrauterine growth retardation (IUGR), postpartum hemorrhage), neonatal outcomes (weight, first and fifth minute Apgar score, Neonatal Intensive Care Unit (NICU) admission, mortality, respiratory distress, and icterus) were recorded using a questionnaire.


RESULTS
Preterm labor, gestational diabetes, and preeclampsia were significantly higher in ART group compared to spontaneous pregnancy group. However, other factors such as anemia, IUGR, postpartum hemorrhage, and intrauterine fetal death (IUFD) were not significantly different between groups. There were no significant differences between groups in terms of neonatal outcomes (weight, 1(st) and 5(th) min Apgar score <7, NICU hospitalization, mortality, respiratory distress, and icterus).


CONCLUSIONS
With regard of significantly higher poor outcomes such as preeclampsia, gestational diabetes and preterm labor in ART group, the couples should be aware of these potential risks before choosing ART.
Department of Obstetrics and Gynecology, Women's Health Research Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Leila
L
Pourali
Department of Obstetrics and Gynecology, Women's Health Research Center, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Sedigheh
S
Ayati
Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Shahrzad
S
Jelodar
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ahmadreza
A
Zarifian
Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Mohammad Sobhan
MS
Sheikh Andalibi
ART; Outcome; Preeclampsia; Twin pregnancy