Intimate gut interactions: helminths and the microbiota.
Changing exposure to intestinal helminths, or alterations in our intestinal microbiome, have been independently proposed to underlie the increasing incidence of chronic inflammatory diseases including allergy, autoimmunity and inflammatory bowel disease (IBD) observed in developed nations. A recent study in Science links these findings by showing that intestinal helminth infection can prevent the outgrowth of a common intestinal bacterium that causes IBD in genetically susceptible mice.
Global Health Institute, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), station 19, 1015 Lausanne, Switzerland.
Nicola L
NL
Harris
D000818:Animals; D003924:Diabetes Mellitus, Type 2; D006373:Helminthiasis; D006376:Helminths; D007422:Intestines; D051379:Mice; D064307:Microbiota