Behcet's disease and pregnancy-a case report and literature review.
This case study reports on a rare case of a woman with Behcet's disease (BD), uterine malformation and antiphospholipid syndrome, who successfully delivered a baby without any complications during the perinatal period. The woman, who was diagnosed with BD with relapsing oral, ocular, and genital involvement 8 years ago, registered in our clinic with a history of two inevitable miscarriages. Laboratory findings were positive for anti-β2-glycoprotein I antibodies (anti-β2-GP-I). Three-dimensional ultrasound showed that her uterus was unicornuate, with only a normal left side. After treatment, the woman had a cesarean section for breech presentation of a healthy male infant weighing 2700 g. The postpartum period was uneventful. The possible effects of BD on pregnancy outcomes and how to manage BD patients are discussed with a review of the literature.
Department of Obstetrics, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Chuanlu
C
Xu
Department of Reproductive Immunology, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai, China.
Shihua
S
Bao
D000022:Abortion, Spontaneous / Q000276:immunology*; D000328:Adult; D000818:Animals; D016736:Antiphospholipid Syndrome / Q000276:immunology*; D001323:Autoantibodies / Q000097:blood*; D001528:Behcet Syndrome / Q000276:immunology*; D002585:Cesarean Section; D005260:Female; D006801:Humans; D008297:Male; D011247:Pregnancy; D011248:Pregnancy Complications / Q000276:immunology*; D011256:Pregnancy Outcome; D014463:Ultrasonography; D014599:Uterus / Q000002:abnormalities
D001323:Autoantibodies
Behcet's disease; antiphospholipid syndrome; autoimmune disease; pregnancy; uterine malformation