The Effect of Hemorheologic Factors on Middle Cerebral Artery Blood Flow Velocity in Young Individuals.
Analysis of the effect of hemorheologic factors on middle cerebral artery (MCA) blood flow velocity in 55 healthy individuals aged 18 to 30 years demonstrated an inverse association between mean MCA blood flow velocity and hematocrit (r = -0.27, p < 0.05). This association was largely explained by the effect of whole-blood viscosity. Neither fibrinogen concentration nor plasma viscosity were significantly associated with MCA blood flow velocity in this group; this lack of a fibrinogen association is in contrast to results previously obtained in elderly individuals where an inverse association was observed. These findings thus demonstrate age-dependent differences in the relationship between fibrinogen and MCA blood flow velocity.
Department of Neurology University of Southern California School of Medicine 2025 Zonal Avenue Los Angeles, CA 90033.
S F
SF
Ameriso
Department of Physiology and Biophysics University of Southern California School of Medicine.
H J
HJ
Meiselman
University of Southern California School of Medicine.
A
A
Saraj
Department of Neurology University of Southern California School of Medicine 2025 Zonal Avenue Los Angeles, CA 90033.
M
M
Fisher