Two Cases of Nevoid Basal Cell CarcinomaSyndrome in One Family.
The nevoid basal cell carcinoma syndrome, or Gorlin-Goltz syndrome, is an autosomal dominant multiple system disorder with high penetrance and variable expressions, although it can also arise spontaneously. The diagnostic criteria for nevoid basal cell carcinoma syndrome include multiple basal cell carcinomas, palmoplantar pits, multiple odontogenic keratocysts, skeletal anomalies, positive family history, ectopic calcification and neurological anomalies. We report a brother and sister who were both diagnosed with nevoid basal cell carcinoma syndrome.
Department of Dermatology and Cutaneous Biology Research Institute,Yonsei University College of Medicine, Seoul, Korea.
Dong Jin
DJ
Ryu
Department of Dermatology and Cutaneous Biology Research Institute,Yonsei University College of Medicine, Seoul, Korea.
Yeon Sook
YS
Kwon
Department of Dermatology and Cutaneous Biology Research Institute,Yonsei University College of Medicine, Seoul, Korea.
Mi Ryung
MR
Roh
Department of Dermatology and Cutaneous Biology Research Institute,Yonsei University College of Medicine, Seoul, Korea.
Min Geol
MG
Lee
Basal cell carcinoma; Nevoid basal cell carcinoma syndrome; Odontogenic keratocyst