Targeting Disease through Metabolism.
The links between cellular and systemic metabolism and different pathologies, including cancer, are on the rise. Cell editor Lara Szewczak asked Doug Green, Ralph DeBerardinis, and Mark Febbraio about what the prospects are for being able to target metabolism therapeutically. An annotated excerpt of the conversation appears below, and the full conversation is available with the article online.
D000818:Animals; D016503:Drug Delivery Systems; D006801:Humans; D008660:Metabolism / Q000187:drug effects*; D009154:Mutation; D009369:Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000276:immunology