Black hairy tongue with a fixed dose combination of olanzapine and fluoxetine.
Black hairy tongue (BHT) is a benign disease characterized by elongated filiform lingual papillae, with a carpet-like appearance of the dorsum of the tongue. It is has been reported to occur with a prevalence ranging from 0.6% to 11.3%. Although its etiology is not fully understood, BHT may be triggered by smoking, excessive coffee or black tea drinking, poor oral hygiene, trigeminal neuralgia, general debilitation, dry mouth as well as certain drugs. We present here a case of a patient with psychosis, depression, and benign prostatic hyperplasia, who developed BHT following treatment with a fixed dose combination (FDC) of olanzapine and fluoxetine and recovered within 3 months after withdrawal of treatment with FDC.
Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Ratinder
R
Jhaj
Department of Pharmacology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Pushp Raj
PR
Gour
Department of Dermatology, All India Institute of Medical Sciences, Bhopal, Madhya Pradesh, India.
Dinesh Prasad
DP
Asati
D000368:Aged; D001569:Benzodiazepines / Q000008:administration & dosage*; D004338:Drug Combinations; D005473:Fluoxetine / Q000008:administration & dosage*; D006801:Humans; D008297:Male; D000077152:Olanzapine; D014064:Tongue, Hairy / Q000139:chemically induced*
D004338:Drug Combinations; D005473:Fluoxetine; D001569:Benzodiazepines; D000077152:Olanzapine
Black hairy tongue; filiform papillae; fluoxetine; olanzapine