Exercise Has a Bone to Pick with Skeletal Muscle.
Exercise intolerance and poor exercise capacity are associated with aging, diabetes, cognitive impairment, and premature death. In this issue of Cell Metabolism, Mera et al. (2016) report that osteocalcin improves endurance exercise performance by enhancing myofiber fuel uptake and utilization, while osteocalcin supplementation reverses the age-induced decline in endurance exercise performance.
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA. Electronic address: boothf@missouri.edu.
Frank W
FW
Booth
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA.
Gregory N
GN
Ruegsegger
Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA.
T Dylan
TD
Olver
D000818:Animals; D001842:Bone and Bones / Q000502:physiology*; D008954:Models, Biological; D018482:Muscle, Skeletal / Q000502:physiology*; D015675:Osteocalcin / Q000378:metabolism; D010805:Physical Conditioning, Animal; D010807:Physical Endurance
D015675:Osteocalcin