Recent Development of Chemosensors Based on Cyanine Platforms.
The cyanine platforms including cyanine, hemicyanine, and squaraine are good candidates for developing chemosensors because of their excellent photophysical properties, outstanding biocompatibility, and low toxicity to living systems. A huge amount of research work involving chemosensors based on the cyanine platforms has emerged in recent years. This review focuses on the development from 2000 to 2015, in which cyanine, hemicyanine, and squaraine sensors will be separately summarized. In each section, a systematization according to the type of detection mechanism is established. The basic principles about the design of the chemosensors and their applications as bioimaging agents are clearly discussed. In addition, we emphasize the advances that have been made in improving the detection performance through incorporation of the chemosensors into nanoparticles.
State Key Laboratory of Fine Chemicals, Dalian University of Technology , 2 Linggong Road, 116024 Dalian, China.
Wen
W
Sun
State Key Laboratory of Fine Chemicals, Dalian University of Technology , 2 Linggong Road, 116024 Dalian, China.
Shigang
S
Guo
State Key Laboratory of Fine Chemicals, Dalian University of Technology , 2 Linggong Road, 116024 Dalian, China.
Chong
C
Hu
State Key Laboratory of Fine Chemicals, Dalian University of Technology , 2 Linggong Road, 116024 Dalian, China.
Jiangli
J
Fan
State Key Laboratory of Fine Chemicals, Dalian University of Technology , 2 Linggong Road, 116024 Dalian, China.
Xiaojun
X
Peng
D000818:Animals; D015374:Biosensing Techniques / Q000379:methods; D002232:Carbocyanines / Q000737:chemistry*; D003503:Cyclobutanes / Q000737:chemistry*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D007211:Indoles / Q000737:chemistry*; D010636:Phenols / Q000737:chemistry*
D002232:Carbocyanines; D003503:Cyclobutanes; D005456:Fluorescent Dyes; D007211:Indoles; D010636:Phenols; C480596:squaraine