Emergence and serovar profiling of non-typhoidal Salmonellae (NTS) isolated from gastroenteritis cases-A study from South India.
Human infection with non-typhoidal Salmonella (NTS) serovars is often a neglected and undiagnosed infection in the developing world. Invasive NTS is now being established as having a new and emerging pathogenic role. There is not sufficient data on the prevalence of NTS serovars and their antibiotic susceptibility pattern from India. Faecal specimens collected from patients with acute gastroenteritis were processed to isolate Salmonella according to the standard protocol for a period from January 2011-December 2014. Salmonella isolates were serotyped and tested for antibiotic susceptibility. Of the total 320 (10.04%) bacterial enteric pathogens isolated, 64 (20%) were non-typhoidal Salmonella. Among the serogroup, O:4 (B) (n = 26; 40.6%) was found to be the commonest followed by O:7 (C1) (n = 11; 17.1%) and O:3,10 (E1) (n = 11; 17.1%). NTS infection in cancer patients could also be termed as nosocomial NTS diarrhoea due to primary community infection with prolonged incubation periods, consumption of contaminated food during hospital stay or Nosocomially acquired infection. Serovar Oslo has been predominant (9/17) in NTS isolates from cancer patients, whereas serovars Bovismorbificans, Wangata and Schleissheim have been reported for the first time in the country. The isolates were mostly susceptible to antibiotics except Salmonella ser Kentucky, which showed resistance to ciprofloxacin is reported for the first time in the country. Continuous surveillance is required to monitor resistance of NTS isolates.
a Enteric Diseases Division , Kasturba Medical College, Manipal University , Manipal , Karnataka , India ;
Mamatha
M
Ballal
a Enteric Diseases Division , Kasturba Medical College, Manipal University , Manipal , Karnataka , India ;
Suganthi Martena
SM
Devadas
a Enteric Diseases Division , Kasturba Medical College, Manipal University , Manipal , Karnataka , India ;
Vignesh
V
Shetty
a Enteric Diseases Division , Kasturba Medical College, Manipal University , Manipal , Karnataka , India ;
Sohan Rodney
SR
Bangera
b Bacteriology Division, National Institute of Cholera and Enteric Diseases , Kolkata , India.
Thandavarayan
T
Ramamurthy
b Bacteriology Division, National Institute of Cholera and Enteric Diseases , Kolkata , India.
Anirban
A
Sarkar
D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000494:pharmacology; D002648:Child; D002675:Child, Preschool; D024881:Drug Resistance, Bacterial; D005243:Feces / Q000382:microbiology; D005759:Gastroenteritis / Q000453:epidemiology* / Q000382:microbiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D015995:Prevalence; D012475:Salmonella / Q000145:classification* / Q000187:drug effects / Q000302:isolation & purification*; D012480:Salmonella Infections / Q000453:epidemiology* / Q000382:microbiology*; D065288:Serogroup; D055815:Young Adult
D000900:Anti-Bacterial Agents
Food-borne infection; antibiotic susceptibility testing; antigenic profiling; faeces culture; non-typhoidal Salmonella