Regulatory T Cells: Molecular Actions on Effector Cells in Immune Regulation.
T regulatory cells play a key role in the control of the immune response, both in health and during illness. While the mechanisms through which T regulatory cells exert their function have been extensively described, their molecular effects on effector cells have received little attention. Thus, this revision is aimed at summarizing our current knowledge on those regulation mechanisms on the target cells from a molecular perspective.
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Asiel
A
Arce-Sillas
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Diana Denisse
DD
Álvarez-Luquín
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Beatriz
B
Tamaya-Domínguez
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Sandra
S
Gomez-Fuentes
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Abel
A
Trejo-García
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Marlene
M
Melo-Salas
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Graciela
G
Cárdenas
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Juan
J
Rodríguez-Ramírez
Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico; Unidad Periférica del Instituto de Investigaciones Biomédicas en el Instituto Nacional de Neurología y Neurocirugía, 14269 México, DF, Mexico.
Laura
L
Adalid-Peralta
D000818:Animals; D002450:Cell Communication / Q000276:immunology; D016207:Cytokines / Q000378:metabolism; D003602:Cytotoxicity, Immunologic; D003713:Dendritic Cells / Q000276:immunology / Q000378:metabolism; D053804:Granzymes / Q000378:metabolism; D006801:Humans; D007107:Immune System / Q000166:cytology / Q000276:immunology / Q000378:metabolism; D007109:Immunity; D056747:Immunomodulation; D008213:Lymphocyte Activation / Q000276:immunology; D054353:Perforin / Q000378:metabolism; D015398:Signal Transduction; D050378:T-Lymphocytes, Regulatory / Q000276:immunology* / Q000378:metabolism*
D016207:Cytokines; D054353:Perforin; D053804:Granzymes