Short report: relationship between restricted and repetitive behaviours in children with autism spectrum disorder and their parents.
BACKGROUND
Restricted and repetitive behaviours (RRBs) constitute a core symptom domain of autism spectrum disorder (ASD). However, the nature of RRBs in the context of the Broader Autism Phenotype (BAP) is not well understood. In particular, the relationship between RRBs in ASD probands and their parents remains largely unexplored. The current study explored the link between parental RRBs, measured via Interest in Patterns and Resistance to Changes subscales of the Autism Quotient and their children's RRBs, measured via Autism Diagnostic Observation Schedule RRB standardized domain score.


RESULTS
Having both parents within the top 20% of their RRB scores was associated with an increase of RRB scores for their children; however, no parent-of-origin effects were identified. Although the trend was observed for both Interest in Patterns and Resistance to Changes subscale, it was only statistically significant for Interest in Patterns.


CONCLUSIONS
This paper provides significant contribution to our understanding of association between RRBs in parents and their children with ASD. Future work should also address the BAP in distinct genetic subtypes (whole chromosome aneuploidies, single gene mutations, copy number variations) of neurodevelopmental and neuropsychiatric disorders that involve RRBs.
Olga Tennison Autism Research Centre, School of Psychology and Public Health, La Trobe University, Bundora, Victoria 3086 Australia ; Cooperative Research Centre for Living with Autism (Autism CRC), Long Pocket, Brisbane, Queensland Australia.
Mirko
M
Uljarević
Department of Psychology, Bucknell University, Lewisburg, PA USA.
David W
DW
Evans
Telethon Kids Institute, University of Western Australia, Perth, WA Australia.
Gail A
GA
Alvares
Telethon Kids Institute, University of Western Australia, Perth, WA Australia.
Andrew J O
AJ
Whitehouse
D000293:Adolescent; D000328:Adult; D000067877:Autism Spectrum Disorder / Q000175:diagnosis* / Q000503:physiopathology; D002648:Child; D002652:Child Behavior / Q000502:physiology; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010290:Parents / Q000523:psychology*; D010641:Phenotype; D013239:Stereotyped Behavior
Autism; Broader Autism Phenotype; Parents; Repetitive behaviours