Effects of 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester on growth and blood components in growing Holstein steers.
Twenty-four Chinese Holstein growing steers were randomly divided into three groups and fed a diet containing 0 (the control group), 15 (treatment I group, or TG1) or 25 (treatment II group, or TG2) g/day 2-hydroxy-4-(methylthio) butanoic acid isopropyl ester (HMBi). Compared with the control group, the final body weights, total gains and average daily gains in the treatment groups increased (P < 0.01). The concentration of total protein (TP) for TG1 increased (P < 0.01). The levels of albumin in TG1 were higher than those in TG2 and the control group (P < 0.05). The concentration of alanine aminotransferase (ALT) in TG2 increased (P < 0.05), but concentrations of aspartate aminotransferase (AST) in the treatment groups decreased (P < 0.05). HMBi improved the concentrations of selenium in both TG1 (P < 0.05) and TG2 (P < 0.01). The levels of glutathion peroxidase (GSH-Px) in TG2 were higher than those of the control group (P < 0.05). Moreover, HMBi increased the concentrations of growth hormone (GH) in both TG1 (P < 0.05) and TG2 (P < 0.01). These results indicate that the addition of HMBi increases growth performance, serum concentrations of GH and AST; 15 g/day HMBi increases concentrations of total protein and albumin, and 25 g/day HMBi increases concentrations of ALT and GSH-Px.
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Zhaoyu
Z
Han
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Baokui
B
Yang
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Zhen
Z
Yang
College of Animal Science and Technology, Nanjing Agricultural University, Nanjing, Jiangsu, China.
Yumeng
Y
Xi
D000410:Alanine Transaminase / Q000097:blood; D000824:Animal Nutritional Physiological Phenomena / Q000502:physiology*; D000818:Animals; D001219:Aspartate Aminotransferases / Q000097:blood*; D001798:Blood Proteins; D002087:Butyrates / Q000008:administration & dosage* / Q000494:pharmacology*; D002417:Cattle / Q000097:blood* / Q000235:genetics*; D004032:Diet / Q000662:veterinary*; D019587:Dietary Supplements; D005979:Glutathione Peroxidase / Q000097:blood*; D013006:Growth Hormone / Q000097:blood*; D008297:Male; D012643:Selenium / Q000097:blood; D012709:Serum Albumin; D015430:Weight Gain
C534403:2-hydroxy-4-(methylthio)butanoic acid isopropyl ester; D001798:Blood Proteins; D002087:Butyrates; D012709:Serum Albumin; D013006:Growth Hormone; D005979:Glutathione Peroxidase; D001219:Aspartate Aminotransferases; D000410:Alanine Transaminase; D012643:Selenium
HMBi; Holstein steers; growth; serum biochemical indexes