[Leishmania infantum induced bone lesions in a dog].
A 3-year-old Labrador Retriever originating from Spain was presented with a left-sided hind limb lameness for several months. The orthopedic examination revealed a pain response when palpating the left tarsal joint. Radiographic and computed tomographic studies showed polyostotic, aggressive osteolytic bone lesions with mild erosive arthritis. The diagnosis of canine leishmaniasis was confirmed by bone biopsy and the detection of the pathogen by PCR. Three weeks after initiation of therapy with allopurinol, the dog presented no signs of lameness. Eight months after start of therapy, radiographic examination revealed moderate regression of the osteolytic bone lesions.
Felix Wallborn, Tierklinik Neandertal, Landstraße 51, 42781 Haan, E-Mail: felixwallborn@web.de.
Felix
F
Wallborn
Charlotte
C
Söffler
Philipp
P
Winkels
Marcus
M
Hess
Peter
P
Engelhardt
D000493:Allopurinol / Q000627:therapeutic use; D000818:Animals; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001850:Bone Diseases, Infectious / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*; D004283:Dog Diseases / Q000175:diagnosis / Q000188:drug therapy / Q000469:parasitology* / Q000473:pathology; D004285:Dogs; D007794:Lameness, Animal / Q000469:parasitology; D018314:Leishmania infantum / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000188:drug therapy / Q000473:pathology / Q000662:veterinary*
D000981:Antiprotozoal Agents; D000493:Allopurinol
Leishmaniasis; allopurinol; computed tomography; lameness; osteolysis; radiography