Substitution Effects of Hypervalent Iodine(III) Reagents in the Diamination of Styrene.
The influence of electronic parameters on the reaction performance of hypervalent iodine(III) reagents in the vicinal diamination of styrene has been investigated. It demonstrates the influence of the relative electron density on the aryl substituent of the hypervalent iodine reagent. In these cases, compounds with donor substituents outperform the corresponding acceptor-substituted systems. In line with this observation, a rapid enantioselective diamination was observed for a preformed chiral bisimidoiodine(III) reagent. For the first time, X-ray structural data could be obtained for an isolated chiral bisimidoiodine(III).
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans 16, E-43007 Tarragona, Spain.
R Martín
RM
Romero
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans 16, E-43007 Tarragona, Spain.
José A
JA
Souto
Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Av. Països Catalans 16, E-43007 Tarragona, Spain.|Catalan Institution for Research and Advanced Studies (ICREA) Pg. Lluís Companys 23, 08010 Barcelona, Spain.
Kilian
K
Muñiz