[Evalation of Jingzhi Xiaoban Tablet in Improving Heart Function of Coronary Heart Disease Pa- tients by Doppler Tissue Imaging and Speckle Tracking Imaging Technology].
OBJECTIVE
To evaluate the role of Jiangzhi Xiaoban Tablet (JXT) in improving heartfunction of coronary heart disease (CHD) patients by tissue Doppler imaging (TDI) and speckle trackingimaging (STI) technology.


METHODS
Recruited were 60 inpatients with confirmed CHD by coronary angiography at First Affiliated Hospital, Hunan University of Traditional Chinese Medicine from October 2013to November 2014. They were assigned to the treatment group (group A) and the control group (groupB) according to random digit table, 30 cases in each group. Patients in group A took JXT, 0.45 g/tablet,4 tablets each time, 3 times per day, while those in group B took Simvastatin Tablet, 20 mg/tablet, 1 tablet each time, once per evening. The therapeutic course for all was 8 weeks. The long axis view of theheart of 18 segments STI Peak strain LS and TDI peak systolic Sa parameters were performed in all patients before and after treatment.


RESULTS
Before treatment segments of STI strain LS and TDI longitudinal peak systolic peak Sa were not statistically different between the two groups (P > 0.05). Each segment of STI peak longitudinal strain LS and TDI peak systolic Sa in the two groups were higher after treatment than before treatment (P < 0.05). After treatment each segment of STI parameters of LS and eachTDI segment parameters of Sa were significantly lower in group B than in group A (P < 0.01).


CONCLUSIONS
JXT could improve heart function of CHD patients to different degrees, and its curative effect was betterthan that of routine Western medicine (Simvastatin Tablets) treatment.
Yue-ai
YA
Wang
Xi-jiao
XJ
Yu
Chou-fu
CF
Cheng
Li
L
Yang
Fang
F
Liu
Meng-hong
MH
Zhou
Yun
Y
Tan
D003324:Coronary Artery Disease / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000008:administration & dosage* / Q000627:therapeutic use*; D015150:Echocardiography, Doppler; D006321:Heart / Q000187:drug effects*; D006801:Humans; D019821:Simvastatin / Q000627:therapeutic use; D013607:Tablets
D004365:Drugs, Chinese Herbal; D013607:Tablets; D019821:Simvastatin