Gliomas "Dope Up" for Growth.
An emerging body of data highlights trophic functions of neurotransmitters on proliferation and differentiation of normal neural progenitors. In this issue of Cancer Cell, Dolma et al. document pro-survival functions of a neurotransmitter receptor in glioma progenitor cells, with practical overtones for therapy.
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Brenton R
BR
Paolella
Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address: charles_stiles@dfci.harvard.edu.
Charles D
CD
Stiles
D001932:Brain Neoplasms; D002454:Cell Differentiation; D005910:Glioma / Q000628:therapy*; D006801:Humans; D013234:Stem Cells