Anthropometric, functional capacity, and oxidative stress changes in Brazilian community-living elderly subjects. A longitudinal study.
To examine the changes and relationships among anthropometric, functional and plasma oxidative stress markers in elderly.



longitudinal study.



measurements in 2008 and 2010.



103 community-dwelling men and women aged 67-92.



Anthropometric parameters [waist, hip, arm and calf circumferences; waist-hip ratio, triceps skinfold thickness and others], basic (ADL) and instrumental activities of daily living (IADL)] and plasma oxidative stress markers (α-tocopherol, β-carotene and malondialdehyde) were assessed in 2008 and 2010.



ADL, IADL, body weight, skinfold thickness and circumferences of calf and arm decreased and waist and waist-hip ratio increased from 2008 to 2010. α-Tocopherol decreased and malondialdehyde plasma levels increased during the study period. In multiple logistic regression analyses, increased age (OR=1.12; IC: 1.02-1.23; p=0.02), female gender (OR=8.43; IC: 1.23-57.58; p=0.03), hypertension (OR=0.22; IC: 0.06-0.79; p=0.02), arthritis/arthrosis (OR=0.09; IC: 0.009-0.87; p=0.04) and depression (OR=0.20; IC: 0.04-1.03; p=0.05) were independent risk factors for functional decline.



Fat reduction, muscle loss, central obesity increase, functional decline and worsening of plasma oxidative stress were observed during 2-year follow-up. Some of the risk factors that were identified could be modified to help prevent functional decline in elderly. The factors deserving attention include hypertension, arthritis/arthrosis and depression.
Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: pri_moreira@yahoo.com.br.
Priscila Lucelia
PL
Moreira
Post-Graduation Program in Pathology, Botucatu Medical School at São Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: correa.camila9@gmail.com.
Camila Renata
CR
Correa
Department of Biostatistics, Botucatu, Institute of Biosciences at Sao Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: jecorren@ibb.unesp.br.
José Eduardo
JE
Corrente
Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: cuadrado@fmb.unesp.br.
Luis Cuadrado
LC
Martin
Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: pvboas@fmb.unesp.br.
Paulo Jose Fortes Villas
PJ
Boas
Department of Internal Medicine, Botucatu Medical School, Sao Paulo State University (UNESP), Botucatu, SP, Brazil. Electronic address: ferreira@fmb.unesp.br.
Ana Lucia Anjos
AL
Ferreira
D000203:Activities of Daily Living; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000886:Anthropometry; D001168:Arthritis / Q000453:epidemiology*; D015992:Body Mass Index; D001835:Body Weight; D001938:Brazil / Q000453:epidemiology; D003863:Depression / Q000453:epidemiology; D003866:Depressive Disorder / Q000453:epidemiology*; D005260:Female; D006801:Humans; D006973:Hypertension / Q000453:epidemiology*; D057187:Independent Living; D007592:Joint Diseases / Q000453:epidemiology; D016015:Logistic Models; D008137:Longitudinal Studies; D008297:Male; D008315:Malondialdehyde / Q000097:blood*; D056128:Obesity, Abdominal / Q000453:epidemiology*; D018384:Oxidative Stress; D012307:Risk Factors; D012737:Sex Factors; D012885:Skinfold Thickness; D055105:Waist Circumference; D049629:Waist-Hip Ratio; D024502:alpha-Tocopherol / Q000097:blood*; D019207:beta Carotene / Q000097:blood*
D019207:beta Carotene; D008315:Malondialdehyde; D024502:alpha-Tocopherol
Anthropometry; Arthritis; Brazilian elderly; Disability; Hypertension; Oxidative stress