Etiology and Management of Male Iatrogenic Urethral Stricture: Retrospective Analysis of 172 Cases in a Single Medical Center.
OBJECTIVE
To investigate the etiology and management of male iatrogenic urethral stricture in China.


METHODS
The data of 172 patients with iatrogenic urethral stricture who underwent treatment at a high volume reference center in China from January 2008 to February 2014 were analyzed retrospectively. Databases were analyzed to understand the impact of different types of iatrogenic injury on stricture location, length and treatment of urethral strictures, as well as success rates.


RESULTS
The most common type of iatrogenic stricture was urethral instrumentations in 80 patients (46.51%). Mean stricture length was 3.3 ± 2.54 cm and the longest strictures were those caused by intravesical instillation. Substitution urethroplasty was the most common intervention and was performed in 60.47% (104/172) of patients. The overall success rate was 85.00% (136/160). Univariable analyses revealed that the type of iatrogenic injury was significantly related to restenosis (p = 0.036), and it is more apt to postoperative restenosis in the type of intravesical instillation than others.


CONCLUSIONS
Our results showed that urethral instrumentation is the most common etiology of iatrogenic urethral stricture, and most iatrogenic urethral strictures involve the anterior urethra. The different etiologies are closely associated with stricture location, length and the overall prognosis of urethral strictures.
Department of Urology, Affiliated Sixth People's Hospital, Shanghai Jiao Tong University, Shanghai, China.
Shu-Kui
SK
Zhou
Jiong
J
Zhang
Ying-Long
YL
Sa
San-Bao
SB
Jin
Yue-Min
YM
Xu
Qiang
Q
Fu
Massimo
M
Lazzeri
D002681:China; D006801:Humans; D007049:Iatrogenic Disease; D008297:Male; D012189:Retrospective Studies; D014521:Urethra; D014525:Urethral Stricture