Current Status and Future Prospects for Aptamer-Based Mycotoxin Detection.
Aptamers are single-stranded oligonucleotides with the ability to bind tightly and selectively to a target analyte. High-affinity and specific aptamers for a variety of mycotoxins have been reported over the past decade. Increasingly, these molecular recognition elements are finding applications in biosensors and assays for the detection of mycotoxins in a variety of complex matrixes. This review article highlights the mycotoxin aptamers that are available for mycotoxin detection and the array of biosensing platforms into which they have been incorporated. Key advantages that aptamers have over analogous technology, and areas in which these advantages may be applied for the benefit of practical mycotoxin detection, are also discussed.
Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawa, ON K1S5B6, Canada.
Annamaria
A
Ruscito
Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawa, ON K1S5B6, Canada.
McKenzie
M
Smith
Carleton University, Department of Chemistry, 1125 Colonel By Drive, Ottawa, ON K1S5B6, Canada.
Daniel N
DN
Goudreau
Maria C
MC
DeRosa
D052157:Aptamers, Nucleotide / Q000737:chemistry*; D015374:Biosensing Techniques / Q000379:methods; D009183:Mycotoxins / Q000032:analysis*; D052156:SELEX Aptamer Technique / Q000379:methods
D052157:Aptamers, Nucleotide; D009183:Mycotoxins