Stereoselective synthesis of cyclopentanone-fused benzosultams through Tomita zipper cyclization.
A powerful intermolecular version of the Tomita zipper-cyclization (TZC) reaction was developed to provide functionalized drug-like cyclopentanone-fused benzosultams in good yields with excellent stereoselectivities using organophosphine-catalysis.
School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. ramsc@uohyd.ac.in.
Dhevalapally B
DB
Ramachary
School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. ramsc@uohyd.ac.in.
Patoju M
PM
Krishna
School of Chemistry, University of Hyderabad, Hyderabad-500 046, India. ramsc@uohyd.ac.in.
T Prabhakar
TP
Reddy