Prevalence and antimicrobial resistance of Mycoplasmas and Chlamydiae in patients with genital tract infections in Shanghai, China.
The infections of Mycoplasmas and Chlamydiae are still severe in patients with genital tract diseases and antimicrobial resistance for these organisms has been changing in recent years. In this study, we reported the prevalence status of Ureaplasma urealyticum, Mycoplasma hominis and Chlamydia trachomatis in 965 patients with genital tract infection in Shanghai from January 2011 to December 2014 and analyzed the antimicrobial resistance of U. urealyticum and M. hominis to 12 kinds of antimicrobial drugs by using commercial kits and SPSS13.0 software. Here, we found the infection of U. urealyticum was the most frequent among these three organisms. The total infection rate for containing any organisms of them was 49.5%, and it has been increasing in recent 4 years. Positive rate in female (53.3%) was higher than male's (34.8%), and the high risk population was 20-39 years old (56.7%). Besides, U. urealyticum and M. hominis displayed relative lower resistance rates to minocycline, doxycycline, josamycin and gatifloxacin (6.5%, 7.2%, 13.5% and 8.6%, respectively). However, for erythromycin, roxithromycin, thiamphenicol and clindamycin, the resistance rates were relatively high (41.9%, 47.2%, 62.3% and 74.9%, respectively). U. urealyticum and M. hominis displayed a declined trend of the antimicrobial resistance to 12 kinds of drugs detected in this study. In total, these preliminary data showed the prevalence of Mycoplasmas and Chlamydiae in patients and the antimicrobial resistance status of Mycoplasmas, which has use for reference on both prevention and treatment of diseases caused by them.
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China.
Meiling
M
He
Fengcheng Hospital of Shanghai, No. 9983, Chuan Nan Feng Road, Fengxian, Shanghai, 201411, PR China.
Yanping
Y
Xie
Fengcheng Hospital of Shanghai, No. 9983, Chuan Nan Feng Road, Fengxian, Shanghai, 201411, PR China.
Ruixia
R
Zhang
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China.
Song
S
Gao
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China.
Guangmei
G
Xu
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China.
Lei
L
Zhang
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China.
Peipei
P
Liu
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China.
Yuanyuan
Y
Li
Department of Microbiology, Medical College of Soochow University, No. 199, Ren Ai Road, Suzhou, Jiangsu, 215123, PR China. Electronic address: wushuyan@suda.edu.cn.
Shuyan
S
Wu
D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002681:China; D002690:Chlamydia Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D002692:Chlamydia trachomatis / Q000302:isolation & purification; D024881:Drug Resistance, Bacterial / Q000187:drug effects; D005260:Female; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008826:Microbial Sensitivity Tests; D008875:Middle Aged; D009175:Mycoplasma Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D019535:Mycoplasma hominis / Q000302:isolation & purification; D015995:Prevalence; D060737:Reproductive Tract Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology*; D016869:Ureaplasma Infections / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D016990:Ureaplasma urealyticum / Q000302:isolation & purification; D055815:Young Adult
D000900:Anti-Bacterial Agents
Antimicrobial resistance; Chlamydia trachomatis; Infection; Mycoplasma hominis; Ureaplasma urealyticum