Evaluation of sialic acid levels in patients with hydatidiform mole: a preliminary study.
OBJECTIVE
This study aims to investigate whether hydatidiform mole (HM) disease with malignant potential is significantly associated with increased sialic acid (SA) levels.


METHODS
A total of 114 women were enrolled in this study. Patients were divided into three groups including HM (Group 1, n = 34), control group including non-pregnant healthy patients (Group 2, n = 42), and another control group including healthy pregnant patients within 12 weeks of gestation (Group 3, n = 38). Serum-free SA levels were measured.


RESULTS
There was a statistically significant difference in serum-free SA levels among the groups (p ≤ 0.001). Patients with HM had significantly higher levels compared to the control groups.


CONCLUSIONS
The present study results showed that there was a significant correlation between HM and serum SA level.
H C
HC
Özcan
E
E
Öztürk
S
S
Sucu
M G
MG
Uğur
I
I
Kutlar
O
O
Balat
B
B
Erbağci
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D006828:Hydatidiform Mole / Q000097:blood* / Q000473:pathology; D019158:N-Acetylneuraminic Acid / Q000097:blood*; D011247:Pregnancy; D014594:Uterine Neoplasms / Q000097:blood* / Q000473:pathology
D019158:N-Acetylneuraminic Acid