Tocilizumab-induced hypofibrinogenemia: A report of 7 cases.
Service de médecine interne, centre hospitalier universitaire de Nice, 06200 Nice, France. Electronic address: martis.n@chu-nice.fr.
Nihal
N
Martis
Service de médecine interne, centre hospitalier universitaire de Nice, 06200 Nice, France.
David
D
Chirio
Service de médecine interne, centre hospitalier universitaire de Nice, 06200 Nice, France.
Viviane
V
Queyrel-Moranne
Centre régional de pharmacovigilance, centre hospitalier universitaire de Clermont-Ferrand, 63003 Clermont-Ferrand cedex 01, France.
Marie-Christine
MC
Zenut
Centre régional de pharmacovigilance, centre hospitalier universitaire de Nice, 06200 Nice, France.
Fanny
F
Rocher
Service de médecine interne, centre hospitalier universitaire de Nice, 06200 Nice, France.
Jean-Gabriel
JG
Fuzibet
D000328:Adult; D000347:Afibrinogenemia / Q000139:chemically induced* / Q000453:epidemiology*; D017677:Age Distribution; D000368:Aged; D061067:Antibodies, Monoclonal, Humanized / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D004305:Dose-Response Relationship, Drug; D004334:Drug Administration Schedule; D005260:Female; D005340:Fibrinogen / Q000032:analysis; D005500:Follow-Up Studies; D006801:Humans; D015994:Incidence; D007262:Infusions, Intravenous; D008875:Middle Aged; D018570:Risk Assessment; D012494:Sampling Studies
D061067:Antibodies, Monoclonal, Humanized; D005340:Fibrinogen; C502936:tocilizumab
Biologics; Hypofibrinogenemia; Interleukin-6; Tocilizumab