How a Piggyback Synapse Listens in to Tune Excitatory Terminals.
In this issue of Neuron, Mende et al. (2016) report how axo-axonic synapses of interneurons balance the strength of glutamatergic terminals in the spinal cord. The results highlight presynaptic roles of mGluR1 receptors and of BDNF as a retrograde signal to regulate GABA synthesis and tune transmission.
Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA.
Tony
T
Cijsouw
Department of Neuroscience, Tufts University School of Medicine, Boston, MA 02111, USA. Electronic address: thomas.biederer@tufts.edu.
Thomas
T
Biederer
D001369:Axons; D005680:gamma-Aminobutyric Acid; D007395:Interneurons; D009474:Neurons; D017729:Presynaptic Terminals; D013116:Spinal Cord; D013569:Synapses
D005680:gamma-Aminobutyric Acid