Microbial Transformation of Carbazole to Anthranilic Acid by Pseudomonas stutzeri.
This study examined the microbial transformation of carbazole (CZ) by an isolated bacterium that can use CZ as a sole carbon and nitrogen source. The strain identified as Pseudomonas stutzeri produced a large amount of anthranilic acid (AA) from CZ in the medium containing a nonionic surfactant. In dialysis culture using ion-exchange resin, 7.9 g/liter (58mm) of AA was accumulated from 15g/liter (90mm) of CZ and the molar yield of AA reached about 64%.
a Central research Laboratories, Idemitsu Kosan Co., Ltd. , 1280 Kamiizumi, Sodegaura, Chiba 299-02 , Japan.
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Hisatsuka
a Central research Laboratories, Idemitsu Kosan Co., Ltd. , 1280 Kamiizumi, Sodegaura, Chiba 299-02 , Japan.
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Sato