Anti-proliferative constituents from Selaginella moellendorffii.
Two new compounds, (3R)-5,6,7-trihydroxy-3-isopropyl-3-methylisochroman-1-one (1) and rhamnocitrin-3-O-β-glucopyranosyl-4'-O-β-galactosyl-(1 --> 3)-glucopyranoside (2), were isolated from the whole plants of Selaginella moellendorffii Hieron. Their structures were determined by spectroscopic methods Additionally, compound 1 could inhibit the proliferation of HT29 cells through inducing cell apoptosis.
Xiao-Feng
XF
Zhoua
Guo-tong
GT
Tong
Xiao-Wen
XW
Wang
Yi
Y
He
D000972:Antineoplastic Agents, Phytogenic / Q000737:chemistry / Q000302:isolation & purification*; D004353:Drug Evaluation, Preclinical; D019073:HT29 Cells; D006801:Humans; D032503:Selaginellaceae / Q000737:chemistry*
D000972:Antineoplastic Agents, Phytogenic