[Optimization of antisecretory component of severe acute pancreatitis intensive management].
OBJECTIVE
Improvement of complex intensive care of severe acute pancreatitis with use of continued intravenous infusion of octreotid.


METHODS
85 patients with severe acute pancreatitis were involved into the investigation, were divided into 2 groups. Patients of the control group (44 patients) got an intensive care according to severe acute pancreatitis treatment. Complex intensive treatment of the group of comparison (41 patients) included injections of octreotid (300 mcg 3 times a day).


RESULTS
The change of octreotid usege scheme allowed to improve treatment resultes, wchis is the decrease of endotoxemia level and minimization of time spent at emergency department.
V.I. Razumovsky Saratov State Medical University, Russia.
E D
ED
Alexandrova
V.I. Razumovsky Saratov State Medical University, Russia.
D V
DV
Sadchikov
V.I. Razumovsky Saratov State Medical University, Russia.
A V
AV
Kuligin
D003422:Critical Care / Q000379:methods; D004305:Dose-Response Relationship, Drug; D016903:Drug Monitoring; D004359:Drug Therapy, Combination / Q000379:methods; D019446:Endotoxemia / Q000209:etiology / Q000628:therapy; D005260:Female; D005440:Fluid Therapy / Q000379:methods; D005765:Gastrointestinal Agents / Q000008:administration & dosage; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D015282:Octreotide / Q000008:administration & dosage*; D019283:Pancreatitis, Acute Necrotizing / Q000150:complications / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome
D005765:Gastrointestinal Agents; D015282:Octreotide