[The role of immune system in the control of cancer development and growth].
The role of immune system is the maintenace of the integritiy of the living organism. The elements of the immune system are connected by several ways forming a complex biological network. This network senses the changes of the inner and outer environment and works out the most effective response against infections and tumors. Dysfunction of the immune system leads to the development of cancer development and chronic inflammatory diseases. Modulation of the checkpoints of the immune system opened new perspecitves in the treatment of rheumatological and oncological diseases as well. Beside the potent antiinflammatory activity, new therapies are able to stimulate anticancer activity of the immune system. The result of these recent developments is a better outcome of malignant diseases, which had an unfavorable outcome in the past. Orv. Hetil., 2016, 157(Suppl. 2), 3-8.
Klinikai Központ, Reumatológiai és Immunológiai Klinika, Pécsi Tudományegyetem Pécs, Akác u. 1., 7635.
Gábor
G
Sütő
D048788:Growth and Development; D006801:Humans; D007107:Immune System; D009369:Neoplasms / Q000276:immunology*
biological therapy; biológiai kezelés; cancer growth; daganatnövekedés; immune checkpoint; immune system; immunrendszer; immunrendszeri ellenőrző pont