[The benefits of carvedilol therapy in the treatment of patients with high cardiovascular risk].
Among the variety of cardiologic pharmacological therapy options, beta-blockers stand on a prominent position. There are several reasons for this. On one hand they have numerous indication rounds, even though professional guidelines have recently tended to de-emphasize them for treatments of hypertension without complication or comorbidity. However, in addition to hypertonic cases associated with cardiac complication, they play a fundamental role in treating heart failure and arrhythmia and the different clinical manifestations (stable angina pectoris, myocardial state) of ischemic heart disease. The decade long development of the pharmacological group made its hemodynamic effects ever more refined. On the other hand we must not neglect the fact that more and more features came to light that positively influence the outcome of cardiovascular diseases. Verification of these latter features in numerous multicentric studies showed how to achieve a beneficial effect on survivability, independent on even hemodynamic effects during beta-blocker therapy.
Kardiológiai Osztály, Petz Aladár Megyei Oktató Kórház Győr, Vasvári Pál út 2-4., 9024.
Zsolt
Z
Fi
Kardiológiai Osztály, Petz Aladár Megyei Oktató Kórház Győr, Vasvári Pál út 2-4., 9024.
Veronika
V
Szentes
D000319:Adrenergic beta-Antagonists / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D000787:Angina Pectoris / Q000188:drug therapy; D000959:Antihypertensive Agents / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D017298:Bisoprolol / Q000494:pharmacology; D002227:Carbazoles / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000188:drug therapy / Q000378:metabolism / Q000503:physiopathology / Q000517:prevention & control*; D000077261:Carvedilol; D002986:Clinical Trials as Topic; D011307:Drug Prescriptions / Q000706:statistics & numerical data; D019317:Evidence-Based Medicine; D006333:Heart Failure / Q000188:drug therapy; D006439:Hemodynamics / Q000187:drug effects*; D006801:Humans; D006814:Hungary; D006973:Hypertension / Q000150:complications / Q000188:drug therapy* / Q000378:metabolism; D008790:Metoprolol / Q000494:pharmacology; D015337:Multicenter Studies as Topic; D018384:Oxidative Stress / Q000187:drug effects; D011320:Primary Health Care / Q000592:standards; D011412:Propanolamines / Q000493:pharmacokinetics / Q000494:pharmacology* / Q000627:therapeutic use; D012306:Risk
D000319:Adrenergic beta-Antagonists; D000959:Antihypertensive Agents; D002227:Carbazoles; D011412:Propanolamines; D000077261:Carvedilol; D008790:Metoprolol; D017298:Bisoprolol
angina pectoris; beta-blockers; béta-blokkolók; carvedilol; diabetes mellitus; heart failure; hypertension; hypertonia; oxidative stress; oxidatív stressz; szívelégtelenség