Added Value of Avian Influenza (H5) Day-Old Chick Vaccination for Disease Control in Egypt.
The immunity profile against H5N1 highly pathogenic avian influenza (HPAI) in the commercial poultry value chain network in Egypt was modeled with the use of different vaccination scenarios. The model estimated the vaccination coverage, the protective seroconversion level, and the duration of immunity for each node of the network and vaccination scenario. Partial budget analysis was used to compare the benefit-cost of the different vaccination scenarios. The model predicted that targeting day-old chick avian influenza (AI) vaccination in industrial and large hatcheries would increase immunity levels in the overall poultry population in Egypt and especially in small commercial poultry farms (from <30% to >60%). This strategy was shown to be more efficient than the current strategy of using inactivated vaccines. Improving HPAI control in the commercial poultry sector in Egypt would have a positive impact to improve disease control.
A UPR AGRIS, Centre International de Recherche en Agriculture pour le Développement, 34398, Montpellier, France.
Marisa
M
Peyre
B UMR MIVEGEC, 34394, Montpellier, France; Oxford University Clinical Research Unit (OUCRU), Hanoi, Vietnam.
Marc
M
Choisy
C Food and Agriculture Organization of the United Nations, P.O. Box 2223, Cairo, Egypt.
Heba
H
Sobhy
C Food and Agriculture Organization of the United Nations, P.O. Box 2223, Cairo, Egypt.|D Reference Laboratory for Veterinary Quality on Poultry Production, 12618, Cairo, Egypt.
Walid H
WH
Kilany
A UPR AGRIS, Centre International de Recherche en Agriculture pour le Développement, 34398, Montpellier, France.
Marie
M
Gély
E Food and Agriculture Organization of the United Nations, 00153, Rome, Italy.
Astrid
A
Tripodi
E Food and Agriculture Organization of the United Nations, 00153, Rome, Italy.
Gwenaëlle
G
Dauphin
F General Organization for Veterinary Services, 12618, Cairo, Egypt.
Mona
M
Saad
A UPR AGRIS, Centre International de Recherche en Agriculture pour le Développement, 34398, Montpellier, France.
François
F
Roger
E Food and Agriculture Organization of the United Nations, 00153, Rome, Italy.
Juan
J
Lubroth
C Food and Agriculture Organization of the United Nations, P.O. Box 2223, Cairo, Egypt.
Yilma
Y
Jobre
D000818:Animals; D002645:Chickens; D004534:Egypt; D053124:Influenza A Virus, H5N1 Subtype / Q000235:genetics / Q000276:immunology*; D007252:Influenza Vaccines / Q000008:administration & dosage* / Q000235:genetics / Q000276:immunology; D005585:Influenza in Birds / Q000196:embryology / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D011201:Poultry Diseases / Q000276:immunology / Q000517:prevention & control* / Q000821:virology; D014611:Vaccination; D015164:Vaccines, Inactivated / Q000008:administration & dosage / Q000235:genetics / Q000276:immunology
D007252:Influenza Vaccines; D015164:Vaccines, Inactivated
Egypt; avian influenza; benefit-cost; hatchery; immunity; model; network; vaccination