An ontology-driven, case-based clinical decision support model for removable partial denture design.
We present the initial work toward developing a clinical decision support model for specific design of removable partial dentures (RPDs) in dentistry. We developed an ontological paradigm to represent knowledge of a patient's oral conditions and denture component parts. During the case-based reasoning process, a cosine similarity algorithm was applied to calculate similarity values between input patients and standard ontology cases. A group of designs from the most similar cases were output as the final results. To evaluate this model, the output designs of RPDs for 104 randomly selected patients were compared with those selected by professionals. An area under the curve of the receiver operating characteristic (AUC-ROC) was created by plotting true-positive rates against the false-positive rate at various threshold settings. The precision at position 5 of the retrieved cases was 0.67 and at the top of the curve it was 0.96, both of which are very high. The mean average of precision (MAP) was 0.61 and the normalized discounted cumulative gain (NDCG) was 0.74 both of which confirmed the efficient performance of our model. All the metrics demonstrated the efficiency of our model. This methodology merits further research development to match clinical applications for designing RPDs. This paper is organized as follows. After the introduction and description of the basis for the paper, the evaluation and results are presented in Section 2. Section 3 provides a discussion of the methodology and results. Section 4 describes the details of the ontology, similarity algorithm, and application.
Center of Digital Dentistry, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Department of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|National Engineering Laboratory for Digital and Material Technology of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Research Center of Engineering and Technology for Digital Dentistry of Ministry of Health, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Beijing Key Laboratory of Digital Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.
Qingxiao
Q
Chen
Tsinghua-Rohm Electronic Engineering Hall 8-301,Tsinghua University, Beijing, 100084, PR China.
Ji
J
Wu
Tsinghua-Rohm Electronic Engineering Hall 8-301,Tsinghua University, Beijing, 100084, PR China.
Shusen
S
Li
Center of Digital Dentistry, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Department of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|National Engineering Laboratory for Digital and Material Technology of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Research Center of Engineering and Technology for Digital Dentistry of Ministry of Health, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Beijing Key Laboratory of Digital Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.
Peijun
P
Lyu
Center of Digital Dentistry, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Department of Prosthodontics, Peking University School and Hospital of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|National Engineering Laboratory for Digital and Material Technology of Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Research Center of Engineering and Technology for Digital Dentistry of Ministry of Health, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.|Beijing Key Laboratory of Digital Stomatology, 22 Zhongguancun Avenue South, Haidian District, Beijing 100081, PR China.
Yong
Y
Wang
Tsinghua-Rohm Electronic Engineering Hall 8-301,Tsinghua University, Beijing, 100084, PR China.
Miao
M
Li
D000465:Algorithms; D064229:Biological Ontologies; D020000:Decision Support Systems, Clinical; D003661:Decision Support Techniques; D003781:Denture Retention; D003832:Denture, Partial, Removable; D006801:Humans; D051188:Knowledge Bases; D009323:Natural Language Processing; D015203:Reproducibility of Results