Preeclampsia and preterm delivery: A population-based case-control study.
OBJECTIVE
To determine the contribution of preeclampsia toward preterm birth in primiparous women.


METHODS
This large population-based case-control study used the Aberdeen Maternity and Neonatal Databank to analyze data on primiparous women with singleton pregnancies, who delivered between 1997 and 2012.


RESULTS
A significant positive association was found between preeclampsia and preterm birth (adjusted odds ratio 4.43; 95% confidence interval 3.80-5.16). Magnitude of association varied according to the onset of delivery and year of delivery.


CONCLUSIONS
Preeclampsia is an important contributor to preterm delivery in this setting and therefore a potentially useful condition to target in order to reduce preterm rates.
a Public Health, Summerfield House , NHS Grampian , Aberdeen , Scotland , UK.
Emma L
EL
Davies
a Public Health, Summerfield House , NHS Grampian , Aberdeen , Scotland , UK.|b Immpact, School of Medicine and Dentistry , University of Aberdeen , Aberdeen , Scotland , UK.
Jacqueline S
JS
Bell
c Obstetric Epidemiology , Dugald Baird Centre for Research on Women's Health, Aberdeen Maternity Hospital , Aberdeen , Scotland , UK.
Sohinee
S
Bhattacharya
D000328:Adult; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D011225:Pre-Eclampsia / Q000175:diagnosis* / Q000503:physiopathology; D011247:Pregnancy; D047928:Premature Birth / Q000209:etiology* / Q000503:physiopathology; D012307:Risk Factors; D012907:Smoking / Q000009:adverse effects; D055815:Young Adult
Case–control study; gestational hypertension; perinatal morbidity and mortality; preeclampsia