Clinical Outcomes of Heart-Lung Transplantation: Review of 10 Single-Center Consecutive Patients.
BACKGROUND
Heart-lung transplantation (HLT) has provided hope to patients with end-stage lung disease and irreversible heart dysfunction. We reviewed the clinical outcomes of 10 patients who underwent heart-lung transplantation at Asan Medical Center.


METHODS
Between July 2010 and August 2014, a total of 11 patients underwent HLT at Asan Medical Center. After excluding one patient who underwent concomitant liver transplantation, 10 patients were enrolled in our study. We reviewed the demographics of the donors and the recipients' baseline information, survival rate, cause of death, and postoperative complications. All patients underwent follow-up, with a mean duration of 26.1±16.7 months.


RESULTS
Early death occurred in two patients (20%) due to septic shock. Late death occurred in three patients (38%) due to bronchiolitis obliterans (n=2) and septic shock (n=1), although these patients survived for 22, 28, and 42 months, respectively. The actuarial survival rates at one year, two years, and three years after HLT were 80%, 67%, and 53%, respectively.


CONCLUSIONS
HLT is a procedure that is rarely performed in Korea, even in medical centers with large heart and lung transplant programs. In order to achieve acceptable clinical outcomes, it is critical to carefully choose the donor and the recipient and to be certain that all aspects of the transplant procedure are planned in advance with the greatest care.
Department of Thoracic and Cardiovascular Surgery, University of Ulsan College of Medicine.
Jae Kwang
JK
Yun
Department of Thoracic and Cardiovascular Surgery, University of Ulsan College of Medicine.
Se Hoon
SH
Choi
Department of Thoracic and Cardiovascular Surgery, University of Ulsan College of Medicine.
Seung-Il
SI
Park
Complication; Heart-lung transplantation; Mortality