Immunological Adjuvant Activity of Pectinioside A, the Steroidal Saponin from the Starfish Patiria pectinifera.
The steroidal saponin, pectinioside A, was isolated from the starfish, Patiria pectinifera. When it was subcutaneously injected into mice with ovalbumin (OVA), it facilitated the production of OVA-specific total IgG and IgG1 but not IgG2a. To our knowledge, this is the first report suggesting that starfish saponin has the potential to be an immunological adjuvant, stimulating Th2 type immune response.
Osamu
O
Kawase
Osamu
O
Ohno
Kiyotake
K
Suenaga
Xuenan
X
Xuan
D000276:Adjuvants, Immunologic / Q000737:chemistry / Q000302:isolation & purification*; D000818:Animals; D005260:Female; D051379:Mice; D015394:Molecular Structure; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification*; D013215:Starfish / Q000737:chemistry*
D000276:Adjuvants, Immunologic; D012503:Saponins; C000609532:pectinioside A