Mediastinal granuloma: a rare cause of dysphagia.
Dysphagia is commonly attributed to disorders arising from dysfunction of the oesophageal mucosa or oesophageal motility. Mediastinal structures causing compression of the oesophagus remain a rare presenting cause of dysphagia. We report a case of a woman presenting with dysphagia to solid foods and associated symptoms of weight loss. Traditional evaluation for dysphagia was unrevealing until cross-sectional imaging suggested a mediastinal obstructive process. The finding of a mediastinal granuloma, distinct from mediastinal fibrosis, as the aetiology of dysphagia is a rare finding, with specific treatment implications. The patient was treated with itraconazole antifungal therapy with an improvement in her symptoms.
Department of Gastroenterology, Hepatology and Nutrition, University of Chicago, Chicago, Illinois, USA.
Dejan
D
Micic
Department of Pulmonary and Critical Care, University of Chicago, Chicago, Illinois, USA.
Douglas Kyle
DK
Hogarth
Department of Gastroenterology, Hepatology and Nutrition, University of Chicago, Chicago, Illinois, USA.
Robert T
RT
Kavitt
D000328:Adult; D000935:Antifungal Agents / Q000008:administration & dosage; D003680:Deglutition Disorders / Q000188:drug therapy / Q000209:etiology*; D003937:Diagnosis, Differential; D005260:Female; D006099:Granuloma / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D006801:Humans; D017964:Itraconazole / Q000008:administration & dosage; D008477:Mediastinal Diseases / Q000150:complications* / Q000000981:diagnostic imaging* / Q000188:drug therapy; D016896:Treatment Outcome; D015431:Weight Loss
D000935:Antifungal Agents; D017964:Itraconazole