Results of the Women's Self-Performed Anal Pap Trial in Human Immunodeficiency Virus-Infected Women.
High-risk human papillomavirus anal infections are common in human immunodeficiency virus-infected women. We conducted a cross-over study in 30 women seen in a California human immunodeficiency virus clinic, to test the feasibility of self-performed anal Pap smears. Women found the tests acceptable and feasible. Compared with physician-collected specimens, results were highly concordant for anal cytology (κ = 0.53) and high-risk human papillomavirus typing (κ = 0.59 inclusive of equivocal results, or κ = 0.81 excluding equivocal results).
From the *Section on Infectious Diseases, Department of Internal Medicine, Wake Forest School of Medicine, Winston-Salem, NC; †Department of Pathology, Stanford University, Stanford; ‡Collaborative Health and Human Services, California State University, Monterey Bay; §San Mateo County Health System, Section of Infectious Diseases and Stanford University, Division of Infectious Diseases and Geographic Medicine, and ¶Division of Pediatric Infectious Diseases, Department of Pediatrics, Stanford University, Stanford, CA.
Candice J
CJ
McNeil
Christina S
CS
Kong
Andrew
A
Anglemyer
Vivian
V
Levy
Yvonne
Y
Maldonado
D000328:Adult; D001003:Anal Canal / Q000821:virology; D001004:Anus Diseases / Q000150:complications / Q000175:diagnosis*; D002140:California; D018592:Cross-Over Studies; D005240:Feasibility Studies; D005260:Female; D015658:HIV Infections / Q000150:complications*; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000302:isolation & purification*; D030361:Papillomavirus Infections / Q000150:complications / Q000175:diagnosis*; D012648:Self Care; D013048:Specimen Handling