Disseminated Hemangiosarcoma in a Juvenile Rhesus Macaque (Macaca mulatta).
Hemangiosarcoma is a malignant tumor of vascular endothelial origin that is sporadically reported in rhesus macaques. This report describes the clinicopathologic features of a 1-y-old rhesus macaque with spontaneous disseminated hemangiosarcoma that originally presented as a focal cutaneous mass. Histopathologic examination of multiple tumor foci revealed regions in which the neoplastic cells formed diffuse sheets, as well as the well-defined vascular channels typically associated with hemangiosarcoma. Multiple endothelial cell immunomarkers were used to confirm the diagnosis in this rhesus macaque. The tumor exhibited staining properties consistent with those seen in domestic animals and humans. In addition, to our knowledge, this animal represents the youngest case of any form of spontaneous hemangiosarcoma reported in the rhesus macaque to date.
Michale E. Keeling Center for Comparative Medicine and Research Department of Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Bastrop, Texas, USA; Albert Einstein College of Medicine, Department of Pathology, Bronx, New York, USA. amanda.beck@einstein.yu.edu.
Amanda P
AP
Beck
Michale E. Keeling Center for Comparative Medicine and Research Department of Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Bastrop, Texas, USA.
Stanton B
SB
Gray
Michale E. Keeling Center for Comparative Medicine and Research Department of Veterinary Sciences, The University of Texas MD Anderson Cancer Center, Bastrop, Texas, USA.
Beth K
BK
Chaffee
D000818:Animals; D003937:Diagnosis, Differential; D006394:Hemangiosarcoma / Q000473:pathology / Q000662:veterinary*; D008253:Macaca mulatta; D008297:Male; D008992:Monkey Diseases / Q000473:pathology*