Phosphate enemas and GFR decline: it's premature to sound the alarm.
Oral sodium phosphate solutions can cause acute phosphate nephropathy, resulting in acute kidney injury and chronic kidney disease. A recent cohort study suggests that phosphate enemas may also be associated with a decline in glomerular filtration rate, but further study is needed to establish a causal relationship.
Department of Pathology, Columbia University Medical Center, New York, New York, USA. Electronic address: gsm17@cumc.columbia.edu.
Glen S
GS
Markowitz
Division of Nephrology, Columbia University Medical Center, New York, New York, USA.
Andrew S
AS
Bomback
Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut, USA.
Mark A
MA
Perazella
D015331:Cohort Studies; D004733:Enema; D005919:Glomerular Filtration Rate; D006801:Humans; D010710:Phosphates; D051436:Renal Insufficiency, Chronic
D010710:Phosphates