Multiple Coronary Artery Aneurysms and Thoracic Aortitis Associated with IgG4-related Disease.
A 60-year-old man was admitted due to the onset of right coronary artery (RCA) aneurysms. Coronary angiography showed two RCA aneurysms and focal stenosis with limitations in the blood flow. Balloon angioplasty was performed. However, the follow-up coronary angiography showed restenosis, an enlarged proximal aneurysm and a newly formed aneurysm. The serum immunoglobulin G4 level was elevated to 1,350 mg/dL and fluorodeoxyglucose positron emission tomography showed increased uptake in the ascending aorta, so the patient was diagnosed with immunoglobulin G4-related vascular disease. The prevention of further enlargement of the aneurysms and an improvement in the RCA flow were achieved with steroid therapy. Steroid therapy may therefore be effective for immunoglobulin G4-related vascular disease.
Department of Cardiology, Tenri Hospital, Japan.
Shunsuke
S
Nishimura
Masashi
M
Amano
Chisato
C
Izumi
Maiko
M
Kuroda
Yusuke
Y
Yoshikawa
Yusuke
Y
Takahashi
Sari
S
Imamura
Naoaki
N
Onishi
Yodo
Y
Tamaki
Soichiro
S
Enomoto
Makoto
M
Miyake
Toshihiro
T
Tamura
Hirokazu
H
Kondo
Kazuaki
K
Kaitani
Yoshihisa
Y
Nakagawa
D001011:Aorta / Q000000981:diagnostic imaging / Q000473:pathology*; D001025:Aortitis / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D001327:Autoimmune Diseases / Q000150:complications* / Q000188:drug therapy*; D003323:Coronary Aneurysm / Q000000981:diagnostic imaging / Q000209:etiology* / Q000473:pathology; D017023:Coronary Angiography; D003331:Coronary Vessels / Q000473:pathology*; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008297:Male; D008875:Middle Aged
D007074:Immunoglobulin G