Smart Thin Hydrogel Coatings Harnessing Hydrophobicity and Topography to Capture and Release Cancer Cells.
Smart thin hydrogel coatings are fabricated to capture and release targeted cancer cells by simultaneously tuning surface hydrophobicity and topography. At physiological temperature, the targeted cancer cells are captured on the hydrophobic and wrinkled coating surface. At room temperature, the captured cells are released from the hydrophilic and smooth coating surface.
Beijing National Laboratory for MolecularSciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Luying
L
Wang
Laboratory of Bio-inspired Smart Interface Science, CAS Center for Excellence in Nanoscience, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.
Hongliang
H
Liu
Beijing National Laboratory for MolecularSciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Feilong
F
Zhang
Beijing National Laboratory for MolecularSciences (BNLMS), Key Laboratory of Green Printing, Institute of Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Guannan
G
Li
University of Chinese Academy of Sciences, Beijing, 100049, P. R. China. stwang@mail.ipc.ac.cn.|Laboratory of Bio-inspired Smart Interface Science, CAS Center for Excellence in Nanoscience, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing, 100190, P. R. China. stwang@mail.ipc.ac.cn.
Shutao
S
Wang
D045744:Cell Line, Tumor; D020099:Coated Materials, Biocompatible / Q000494:pharmacology*; D006801:Humans; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate / Q000494:pharmacology*; D057927:Hydrophobic and Hydrophilic Interactions; D013499:Surface Properties; D013696:Temperature
D020099:Coated Materials, Biocompatible; D020136:Hydrogel, Polyethylene Glycol Dimethacrylate
cell capture and release; hydrophobicity; thermoresponsive hydrogels; topography