Echocardiographic Linear Dimensions for Assessment of Right Ventricular Chamber Volume as Demonstrated by Cardiac Magnetic Resonance.
Echocardiography-derived linear dimensions offer straightforward indices of right ventricular (RV) structure but have not been systematically compared with RV volumes on cardiac magnetic resonance (CMR).



Echocardiography and CMR were interpreted among patients with coronary artery disease imaged via prospective (90%) and retrospective (10%) registries. For echocardiography, American Society of Echocardiography-recommended RV dimensions were measured in apical four-chamber (basal RV width, mid RV width, and RV length), parasternal long-axis (proximal RV outflow tract [RVOT]), and short-axis (distal RVOT) views. For CMR, RV end-diastolic volume and RV end-systolic volume were quantified using border planimetry.



Two hundred seventy-two patients underwent echocardiography and CMR within a narrow interval (0.4 ± 1.0 days); complete acquisition of all American Society of Echocardiography-recommended dimensions was feasible in 98%. All echocardiographic dimensions differed between patients with and those without RV dilation on CMR (P < .05). Basal RV width (r = 0.70), proximal RVOT width (r = 0.68), and RV length (r = 0.61) yielded the highest correlations with RV end-diastolic volume on CMR; end-systolic dimensions yielded similar correlations (r = 0.68, r = 0.66, and r = 0.65, respectively). In multivariate regression, basal RV width (regression coefficient = 1.96 per mm; 95% CI, 1.22-2.70; P < .001), RV length (regression coefficient = 0.97; 95% CI, 0.56-1.37; P < .001), and proximal RVOT width (regression coefficient = 2.62; 95% CI, 1.79-3.44; P < .001) were independently associated with CMR RV end-diastolic volume (r = 0.80). RV end-systolic volume was similarly associated with echocardiographic dimensions (basal RV width: 1.59 per mm [95% CI, 1.06-2.13], P < .001; RV length: 1.00 [95% CI, 0.66-1.34], P < .001; proximal RVOT width: 1.80 [95% CI, 1.22-2.39], P < .001) (r = 0.79).



RV linear dimensions provide readily obtainable markers of RV chamber size. Proximal RVOT and basal width are independently associated with CMR volumes, supporting the use of multiple linear dimensions when assessing RV size on echocardiography.
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Radiology, Weill Cornell Medical College, New York, New York. Electronic address: jik9027@med.cornell.edu.
Jiwon
J
Kim
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Aparna
A
Srinivasan
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Tania
T
Seoane
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Antonino
A
Di Franco
Department of Mathematics, New York University, New York, New York.
Charles S
CS
Peskin
Department of Mathematics, New York University, New York, New York.
David M
DM
McQueen
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Tracy K
TK
Paul
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Attila
A
Feher
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Alexi
A
Geevarghese
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Meenakshi
M
Rozenstrauch
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York.
Richard B
RB
Devereux
Greenberg Cardiology Division, Department of Medicine, Weill Cornell Medical College, New York, New York; Department of Radiology, Weill Cornell Medical College, New York, New York.
Jonathan W
JW
Weinsaft
D015984:Causality; D015897:Comorbidity; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging* / Q000453:epidemiology*; D004452:Echocardiography / Q000379:methods*; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging; D006801:Humans; D019028:Magnetic Resonance Imaging, Cine / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009518:New York / Q000453:epidemiology; D009929:Organ Size; D015203:Reproducibility of Results; D012307:Risk Factors; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D018497:Ventricular Dysfunction, Right / Q000000981:diagnostic imaging* / Q000453:epidemiology*
Cardiovascular magnetic resonance; Echocardiography; Right ventricle