Slowly Building Excitement.
While some neurons are tuned to integrate fast and precisely timed inputs, others set behavioral states on much slower timescales. In this issue of Cell, Branco et al. demonstrate that body weight is regulated by hypothalamic neurons using a highly effective form of slow synaptic integration, which is mediated by the voltage gated sodium channel Nav1.7.
Neuronal Networks Group, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany.
Christina
C
Müller
Neuronal Networks Group, German Center for Neurodegenerative Diseases, Ludwig-Erhard-Allee 2, 53175 Bonn, Germany. Electronic address: stefan.remy@dzne.de.
Stefan
S
Remy
D062556:NAV1.7 Voltage-Gated Sodium Channel; D009474:Neurons; D015222:Sodium Channels
D062556:NAV1.7 Voltage-Gated Sodium Channel; D015222:Sodium Channels