Structure of Malformin A, a Phytotoxic Metabolite Produced by Aspergillus niger.
Malformins-produced by Aspergillus niger were separated by HPLC and subjected to structural determination. Amino acid analyses and mass spectra suggested that all of them structurally resembled cyclic pentapeptide malformin A1. Two-dimensional NMR experiments and MS/MS experiments led us to deduce cyclo-D-cysteinyl-D-cysteinyl-L-amino acid-D-amino acid-L-amino acid as being the essential structure of malformins.
a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.|b Department of Agricultural Chemistry , The University of Tokyo , Bunkyo-ku , Tokyo 113 , Japan.
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Kim
a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.
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Sugawara
a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.
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Yoshida
a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.|b Department of Agricultural Chemistry , The University of Tokyo , Bunkyo-ku , Tokyo 113 , Japan.
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Murofushi
a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.
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Takahashi
a The Institute of Physical and Chemical Research (RIKEN) , Wako , Saitama 351-01 , Japan.|c Department of Botany and Plant Pathology , Purdue University , West Lafayette , IN 49707 , U.S.A.
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Curtis