PET-Based Personalized Management of Infectious and Inflammatory Disorders.
It is challenging to diagnose and manage infectious and inflammatory diseases; symptoms are relatively nonspecific, the disease patterns are often systemic. Imaging is pivotal and fluorodeoxyglucose (FDG)-PET/computed tomography (CT) is increasingly used due to its high sensitivity whole-body approach. At present, the literature is still relatively sparse, but evidence for FDG-PET/CT is mounting in several domains, for example, detecting culprit lesions in systemic infections and inflammations, evaluation of disease extent and therapy monitoring, and many other domains have shown considerable potential, for example, atherosclerosis in systemic inflammation. We believe FDG-PET/CT is becoming a first-line modality for infections and inflammation.
Department of Nuclear Medicine, Odense University Hospital, Sdr. Boulevard 29, Odense 5000, Denmark; Division of Nuclear Medicine, Department of Radiology and Nuclear Medicine, Hospital of South West Jutland, Finsensgade 10, Esbjerg 6700, Denmark; Department of Clinical Research, Faculty of Health Sciences, University of Southern Denmark, Winsløwparken 19, 3, Odense 5000, Denmark. Electronic address: Soeren.hess@rsyd.dk.
Søren
S
Hess
Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, University of Pennsylvania Perelman School of Medicine, 3400 Civic Center Boulevard, Building 421, Philadelphia, PA 19104, USA.
Abass
A
Alavi
Radiation Medicine Center (BARC), Tata Memorial Hospital Annexe, E. Borges Marg, Parel, Mumbai-400012, India.
Sandip
S
Basu
D003141:Communicable Diseases / Q000000981:diagnostic imaging*; D006801:Humans; D007249:Inflammation / Q000175:diagnosis*; D049268:Positron-Emission Tomography / Q000379:methods*; D057285:Precision Medicine / Q000379:methods*
FDG; Infection; Infectious disease; Inflammation; Inflammatory disorders; PET/CT