Fungal Keratitis Due to Beauveria bassiana in a Contact Lenses Wearer and Review of Published Reports.
Fungal keratitis is a severe ocular infection that primarily affects subjects engaged in outdoor activities. Risk factors include allergic conjunctivitis, previous eye surgery, previous treatment with wide-spectrum antimicrobial agents and corticosteroids and using contact lenses. Corneal infection is usually secondary to trauma involving organic material, which is often the only predisposing factor. Early diagnosis based on clinical examination and microbiological investigation (microscopy, cultures and molecular techniques) is crucial to selecting the appropriate antifungal therapy and prevent progression. We report the case of a patient with keratitis due to Beauveria bassiana, an opportunistic and entomopathogenic filamentous fungus that is used as a biological insecticide and which is a rare cause of corneal infection. We review previous cases reports of B. bassiana keratitis published and its main features to compare with our case, a female occasional agriculture worker who had not suffered any trauma involving organic material. The patient received topical and oral antifungal therapy and debridement surgery, with a satisfactory outcome.
Servicio de Microbiología, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria ibs, Granada, Spain. analaraoya@gmail.com.
Ana
A
Lara Oya
Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Granada, Spain.
María Eloisa
ME
Medialdea Hurtado
Servicio de Microbiología, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria ibs, Granada, Spain.
María Dolores
MD
Rojo Martín
Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Antonia
A
Aguilera Pérez
Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.
Ana
A
Alastruey-Izquierdo
Servicio de Microbiología, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria ibs, Granada, Spain.
Consuelo
C
Miranda Casas
Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Marina
M
Rubio Prats
Servicio de Oftalmología, Hospital Universitario Virgen de las Nieves, Granada, Spain.
Santiago
S
Medialdea Marcos
Servicio de Microbiología, Hospital Universitario Virgen de las Nieves, Instituto de Investigación Biosanitaria ibs, Granada, Spain.
José María
JM
Navarro Marí
D000935:Antifungal Agents / Q000008:administration & dosage; D052982:Beauveria / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D003261:Contact Lenses / Q000009:adverse effects*; D003646:Debridement; D005260:Female; D006801:Humans; D007634:Keratitis / Q000209:etiology* / Q000473:pathology* / Q000628:therapy; D008875:Middle Aged; D009181:Mycoses / Q000175:diagnosis* / Q000473:pathology* / Q000628:therapy; D016896:Treatment Outcome
D000935:Antifungal Agents
Beauveria bassiana; Contact lenses; Fungal keratitits; Natamycin; Voriconazole