RNA editing in cancer: Mechanistic, prognostic, and therapeutic implications.
We have recently provided a comprehensive analysis of A-to-I RNA editing events in various cancer types, revealing many clinically relevant RNA editing sites and demonstrating that RNA editing can selectively affect cancer drug sensitivity. Our results unveil mechanistic, prognostic, and therapeutic implications for RNA editing in cancer.
Department of Biochemistry and Molecular Biology, The University of Texas Health Science Center at Houston Medical School , Houston, TX, USA.
Leng
L
Han
Department of Bioinformatics and Computational Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Han
H
Liang
Driver events; RNA editing; drug sensitivity; pancancer analysis; prognostic marker