An experimental study on the comparison of the effects of triester glycerol oxide on wound repair.
OBJECTIVE
The aim of this study is to assess the effects of triester glycerol oxide (TGO) on cutaneous wound epithelization process.


METHODS
Fifty-four male Wistar rats were divided into 2 groups of 27 rats each: control(C) and TGO (PX). The groups have been divided into three subgroups which included nine rats each regarding the wound excision on the 3rd, 7th, and 10th days, respectively. The specimens were evaluated according to histological properties and hydroxyproline levels.


RESULTS
Seventh day examination showed that PX and control groups present the same score. HP levels in the control group were significantly lower compared to PX groups.


CONCLUSIONS
TGO have positive effects on wound epithelization process by increased collagen synthesis.
Aksaz Military Hospital, Dental Service, Muğla, Turkey.
Serhat
S
Sezgin
Department of Oral and Maxillofacial Surgery, Gülhane Military Medical Academy, Ankara, Turkey.
Metin
M
Sencimen
Sarikamis Military Hospital, Dental Service, Sarikamis, Kars, Turkey. aydingulses@gmail.com.
Aydin
A
Gülses
Tatvan Military Hospital, Dental Service, Bitlis, Turkey.
Fevzi
F
Erdemci
Center for Implant Dentistry, Duisburg, Germany.|Danube University Krems, Krems, Austria.
Mustafa
M
Ayna
Edremit Military Hospital, Dental Service, Balikesir, Turkey.
İsmail K
İK
Gider
Department of Pathology, Gülhane Military Medical Academy, Ankara, Turkey.
Onder
O
Ongoru
Department of Microbiology, Gülhane Military Medical Academy, Ankara, Turkey.
Tuncer
T
Cayci
D000818:Animals; D003094:Collagen / Q000096:biosynthesis; D005990:Glycerol / Q000494:pharmacology; D008297:Male; D051381:Rats; D017208:Rats, Wistar; D062326:Re-Epithelialization / Q000187:drug effects; D014945:Wound Healing / Q000187:drug effects*
D003094:Collagen; D005990:Glycerol
Epithelization; Hydroxyproline; Triester glycerol oxide; Wound