Evaluation of the Hologic Panther Transcription-Mediated Amplification Assay for Detection of Mycoplasma genitalium.
The detection of Mycoplasma genitalium was evaluated on 1,080 urine samples by the use of a Panther instrument. Overall sensitivity, specificity, positive predictive values, and negative predictive values were 100%, 99.4%, 93.6%, and 100%, respectively. Detection of M. genitalium by the use of the Panther transcription-mediated amplification assay offers a simple, accurate, and sensitive platform for diagnostic laboratories.
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, Australia Murdoch Childrens Research Institute, Parkville, Victoria, Australia sepehr.tabrizi@thewomens.org.au.
S N
SN
Tabrizi
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia.
A M
AM
Costa
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia.
J
J
Su
Hologic, Sydney, NSW, Australia.
P
P
Lowe
Melbourne Sexual Health Centre, Carlton, Victoria, Australia Central Clinical School, Monash University, Victoria, Australia.
C S
CS
Bradshaw
Melbourne Sexual Health Centre, Carlton, Victoria, Australia Central Clinical School, Monash University, Victoria, Australia.
C K
CK
Fairley
Department of Microbiology and Infectious Diseases, The Royal Women's Hospital, Parkville, Victoria, Australia Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, Australia Murdoch Childrens Research Institute, Parkville, Victoria, Australia.
S M
SM
Garland
D005260:Female; D006801:Humans; D008297:Male; D009175:Mycoplasma Infections / Q000175:diagnosis*; D045704:Mycoplasma genitalium / Q000235:genetics / Q000302:isolation & purification*; D021141:Nucleic Acid Amplification Techniques / Q000379:methods*; D011237:Predictive Value of Tests; D011247:Pregnancy; D012680:Sensitivity and Specificity; D014158:Transcription, Genetic; D014526:Urethritis / Q000209:etiology / Q000382:microbiology; D014556:Urine / Q000382:microbiology*