Autocrine TNF-α and IL-1β prime 6-sulfo LacNAc+dendritic cells for high-level production of IL-23.
Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Anja
A
Kunze
Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Ulrike
U
Förster
Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Stephanie
S
Oehrl
Institute of Immunology, Medical Faculty, Technical University of Dresden, Dresden, Germany.
Marc
M
Schmitz
Department of Dermatology, University Hospital Heidelberg, Heidelberg, Germany.
Knut
K
Schäkel
D000606:Amino Sugars / Q000378:metabolism; D019898:Autocrine Communication; D003713:Dendritic Cells / Q000378:metabolism*; D006801:Humans; D053759:Interleukin-23 / Q000378:metabolism*; D011565:Psoriasis / Q000378:metabolism; D014409:Tumor Necrosis Factor-alpha / Q000378:metabolism
C467438:6-sulfo-LacNac; D000606:Amino Sugars; D053759:Interleukin-23; D014409:Tumor Necrosis Factor-alpha
TNF-α; antibody-mediated treatment; psoriasis; slanDC