The impact of progesterone supplementation on pregnancy rates after intrauterine insemination in patients developing a single follicle.
The objective was to determine whether progesterone support affects pregnancy rates in patients who develop a single follicle. This was a non-randomized prospective controlled study performed on 591 intrauterine insemination (IUI) cycles that developed a single follicle; 337 women received 100 mg oral progesterone daily. The pregnancy rate was 24.3%, or 82 out of 337, in the group receiving progesterone support compared with 14.96%, or 254 out of 591, in the group with no progesterone support. IUI luteal phase supplementation with oral progesterone may improve clinical pregnancy rates when begun the day after insemination.
a Faculty of Medicine, Gynecology and Obstetrıcs , Ondokuz Mayıs Üniversity , Samsun , Turkey ;
Davut
D
Güven
b Izmir Faculty of Medicine, Obstetrics and Gynecology , Samsun , Turkey ;
Ali
A
Batıoğlu
c Faculty of Medicine, Obstetrics and Gynecology , Ondokuz Mayıs Üniversity , Samsun , Turkey ;
Seher
S
Sari
d Department of Gynecology and Obstetrics , Private Hospital , Istanbul , Turkey.
Kadir
K
Bakay
D005260:Female; D006801:Humans; D007315:Insemination, Artificial / Q000379:methods*; D011247:Pregnancy; D018873:Pregnancy Rate; D011374:Progesterone / Q000008:administration & dosage*; D011446:Prospective Studies; D016896:Treatment Outcome
D011374:Progesterone
Intrauterine insemination; live-birth rates; pregnancy; progesterone