Cronkhite-Canada Syndrome Complicated by Triple Primary Cancers.
We herein report a case of Cronkhite-Canada syndrome (CCS) complicated with triple primary cancers. The patient was diagnosed with CCS at 65 years of age. At 76 years of age, one of his colon polyps was diagnosed as adenocarcinoma. At 81 years of age, gastric carcinoma was detected. Weight loss and fatigue appeared one month before he visited our hospital. An examination revealed dilatation of the intrahepatic bile duct. Cholangiocarcinoma was diagnosed as a result of bile duct cytology. Patients with CCS should be monitored carefully for carcinoma of systemic organs as well as the gastrointestinal tract.
Department of Internal Medicine & Gastrointestinal Endoscopy, Saga Medical School, Japan.
Kohei
K
Yamanouchi
Yasuhisa
Y
Sakata
Nanae
N
Tsuruoka
Ryo
R
Shimoda
Masahiko
M
Uchida
Takashi
T
Akutagawa
Shimpei
S
Shirai
Kazuma
K
Fujimoto
Ryuichi
R
Iwakiri
D000230:Adenocarcinoma / Q000175:diagnosis; D000368:Aged; D001650:Bile Duct Neoplasms / Q000175:diagnosis; D018281:Cholangiocarcinoma / Q000175:diagnosis; D006801:Humans; D044483:Intestinal Polyposis / Q000150:complications*; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000175:diagnosis*; D013274:Stomach Neoplasms / Q000175:diagnosis