[Not Available].
The combination of magnetoencephalography (MEG) and magnetic resonance imaging (MRI) allows the localization and functional characterization of the somatosensory and motor cortex. However, this method is technically pretentious and time consuming. Therefore, functional imaging is still not established as routine procedure in neurosurgery. The aim of the presented study was the development of a protocol, which allows the integration of functional MEG data into presurgical planning and intraoperative navigation, as a routine method.Forty-five patients with intracranial mass lesions within the central region were examined by MEG. For the somatosensory localization, the median and tibial nerves were electrically stimulated. The motor cortex was localized by tapping of the index finger. The coordinates of the functional dipole source were projected onto a 3D MRI data-set. Finally, the marked MR images were transferred to the neurosurgical navigation system. Following this strategy, after an average time of 3 hours, all data for presurgical planning and intraoperative navigation were available for the neurosurgeon.Our results show that MEG/MRI based functional neuronavigation can be used as a routine tool during daily neurosurgical practice.
Klinik für Neurochirurgie, Eberhard-Karls-Universität Tübingen, Germany.
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D
Freudenstein
Klinik für Neurochirurgie, Eberhard-Karls-Universität Tübingen, Germany.
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F
Duffner
Institut für Medizinische Psychologie und Verhaltensneurobiologie, MEG-Zentrum, Eberhard-Karls-Universität Tübingen, Germany.
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Preißl
Institut für Medizinische Psychologie und Verhaltensneurobiologie, MEG-Zentrum, Eberhard-Karls-Universität Tübingen, Germany.
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W
Lutzenberger
Abteilung für Neuroradiologie, Eberhard-Karls-Universität Tübingen, Germany.
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U
Bühring
Institut für Medizinische Psychologie und Verhaltensneurobiologie, MEG-Zentrum, Eberhard-Karls-Universität Tübingen, Germany.
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N
Birbaumer
Functional imaging; Key Words: Magnetencephalography; Neuronavigation; Neurosurgery; Presurgical planning