Predictors of early vs. late permanent shunt insertion after aneurysmal subarachnoid hemorrhage.
OBJECTIVE
Numerous studies have identified different predictors for secondary hydrocephalus after aneurysmal subarachnoid hemorrhage (SAH), although predictors regarding timing of the shunt operation have never been reported. Predictors for an early shunt, which was defined as a shunt operation performed ≤30 days after SAH onset, and for a late shunt, performed at >40 days, were investigated.


METHODS
A total of 735 consecutive SAH patients admitted to our hospital between 2003 and 2014 who underwent surgery for ruptured aneurysms within five days of onset were retrospectively assessed.


RESULTS
Secondary hydrocephalus developed in 225 patients, including 70 with an early shunt and 96 with a late shunt. Multivariate analysis showed that predictors for secondary hydrocephalus were age ≥70 years, World Federation of Neurosurgical Society (WFNS) grade IV-V, Fisher grade 3-4, intraventricular hemorrhage, anterior cerebral artery aneurysms, and external drainage for acute hydrocephalus (p < 0.05). In the early and late shunt groups, multivariate analysis indicated that early shunt was significantly associated with coil embolization, and late shunt was correlated with middle cerebral artery aneurysms and cerebral infarction due to vasospasm (p < 0.05).


CONCLUSIONS
The difference in the predictors between the early and late shunts implied that the mechanisms of secondary hydrocephalus differed between the early and late shunt groups. Knowledge of the associated risk factors might help to predict the timing of the shunt operation for early rehabilitation planning in the future.
a Department of Neurosurgery , Tokai University , Kanagawa , Japan.
Hideaki
H
Shigematsu
a Department of Neurosurgery , Tokai University , Kanagawa , Japan.
Takatoshi
T
Sorimachi
a Department of Neurosurgery , Tokai University , Kanagawa , Japan.
Takahiro
T
Osada
a Department of Neurosurgery , Tokai University , Kanagawa , Japan.
Rie
R
Aoki
a Department of Neurosurgery , Tokai University , Kanagawa , Japan.
Kittipong
K
Srivatanakul
b Department of Neurosurgery , Tokai University Hachioji Hospital , Tokyo , Japan.
Shinri
S
Oda
a Department of Neurosurgery , Tokai University , Kanagawa , Japan.
Mitsunori
M
Matsumae
D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002557:Cerebrospinal Fluid Shunts / Q000379:methods*; D016009:Chi-Square Distribution; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D013345:Subarachnoid Hemorrhage / Q000150:complications / Q000601:surgery*; D013997:Time Factors
Coil embolization; Normal pressure hydrocephalus; Outcome; Subarachnoid hemorrhage; Ventriculoperitoneal shunt