Celiac disease with Evans syndrome and isolated immune thrombocytopenia in monozygotic twins: a rare association.
Celiac disease is a multisystem immune-mediated disorder caused by exposure to dietary gluten in genetically predisposed individuals. The clinical presentation is characterized by a multitude and diversity of symptoms and complications. The coexistence of celiac disease with other autoimmune disorders has been established, most frequently with type 1 diabetes mellitus and autoimmune thyroiditis. The association of celiac disease with immune-mediated hematologic conditions has been rarely reported. This case study describes a pair of identical twin sisters with celiac disease associated with Evans syndrome in one sibling, and with isolated immune thrombocytopenia in the other.
Department of Pediatrics, Clinical Hospital Center Rijeka School of Medicine, University of Rijeka, Rijeka, Croatia. Electronic address: jelena.roganovic1@ri.t-com.hr.
Jelena
J
Roganovic
D000744:Anemia, Hemolytic, Autoimmune / Q000150:complications*; D002446:Celiac Disease / Q000150:complications*; D002648:Child; D002675:Child, Preschool; D005260:Female; D020022:Genetic Predisposition to Disease; D006801:Humans; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000150:complications*; D013921:Thrombocytopenia / Q000150:complications*; D014430:Twins, Monozygotic
Celiac disease; Evans syndrome; Immune thrombocytopenia