[POSTPRANDIAL ADAPTATION OF PANCREATIC SECRETION. On the 90th anniversary of the outstanding scientist and organizer of science, academician Aleksandr Mikhailovich Ugolev].
OBJECTIVE
Statement of modern traditional and original view on essence and mechanisms of postprandial adaptation of pancreatic enzymes secretion is presented.


RESULTS
The exosecretion of synthesized de novo and recreted pancreatic enzymes is adapted to nutrient content of the meal by means of duodenal-pancreatic stimulated and inhibition peptidergic mechanisms, generalized and selected-induced enzyme-substrate complexes of duodenal chyme. The managed module secreted-transported pancreatic system is important as a normal criterion in urgent adaptation.
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Korot'ko
D000222:Adaptation, Physiological; D004063:Digestion / Q000502:physiology*; D004386:Duodenum / Q000502:physiology; D006801:Humans; D007413:Intestinal Mucosa / Q000502:physiology; D010179:Pancreas / Q000201:enzymology* / Q000378:metabolism*; D019518:Postprandial Period / Q000502:physiology*