Facile Synthesis of Cyanogen Glycosides (R)-Prunasin, Linamarin and (S)-Heterodendrin.
A facile synthetic route is described to cyanogenic glycosides (R)-prunasin, linamarin and (S)-heterodendrin from O-(2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl)trichloroace- timidate and the corresponding α-hydroxyamides by a 3-step reaction of glycosylation, cyanohydrin formation by dehydration of carboxamides, and deprotection.
a Biotechnology Research Center, Toyama Prefectural University.
N
N
Nakajima
a Biotechnology Research Center, Toyama Prefectural University.
M
M
Ubukata
cyanogenic glycoside; cyanohydrin formation; dehydration of carboxamide; facile synthesis; glycosylation