[MICROANGIOPATHIC HEMOLYTIC ANEMIA AS PRESENTING SYMPTOM OF GASTRIC ADENOCARCINOMA].
Metastatic adenocarcinoma presenting as microangiopathic hemolytic anemia (MAHA) is a rare finding. We report the case of a young patient who presented with MAHA as the initial symptom of metastatic gastric adenocarcinoma. Cancer-related microangiopathic hemolytic anemia is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia. A high index of suspicion and prompt diagnosis can prevent ulterior deterioration, especially when chemotherapy is the optimal treatment in these cases, which can stop the hemolysis.
Najib
N
Dally
Marat
M
Kashlikov
Raymond
R
Farah
D000230:Adenocarcinoma / Q000175:diagnosis* / Q000473:pathology; D000328:Adult; D000743:Anemia, Hemolytic / Q000209:etiology*; D006801:Humans; D008297:Male; D009362:Neoplasm Metastasis; D013274:Stomach Neoplasms / Q000175:diagnosis* / Q000473:pathology