Face graft? Extrapolation of facial allotransplantation to children.
The possibility to imagine a vascularized composite allotransplantation for disfigured children is felt more critical than for adults non on technical point of view but in terms of indications and justifications. The question is not about surgery. It is related to the pathologies themselves for which transplant could be suitable. Moreover the procurement of face transplant will be more difficult because of immunologic criteria but also age and phototype. Specificity of the newborn malformative face is usually not only a question of tissue defect. It is reasonably not an indication for VCA. It should be added that nothing is known about the future of transplantation in terms of duration but also morbidities due to immunosuppression. Indications are rather negative. To rise the question of VCA for children has a double benefit. The first is to point out that surgical innovation often arise from a non imaginable or non imagined clinical situation. The second is the question of VCA in newborn regarding the tolerance.
CHU Amiens - Department of Maxillofacial Surgery, France.
Bernard L
BL
Devauchelle
CHU Amiens - Department of Maxillofacial Surgery, France. Electronic address: testelin.sylvie@chu-amiens.fr.
Sylvie R
SR
Testelin
CHU Amiens - Department of Maxillofacial Surgery, France.
Julien
J
Davrou
CHU Amiens - Department of Maxillofacial Surgery, France.
Cécilia
C
Neiva
Department of Plastic and Reconstructive Surgery, University Clinics of Louvain Brussels, Belgium.
Benoît G
BG
Lengele
University Hospital of Lyon - Department of Urology Transplantation, France.
Jean-Michel
JM
Dubernard
CHU Amiens - Department of Maxillofacial Surgery, France.
Stéphanie
S
Dakpe
D000293:Adolescent; D000328:Adult; D002056:Burns / Q000601:surgery*; D002648:Child; D005145:Face / Q000002:abnormalities / Q000601:surgery*; D005151:Facial Injuries / Q000601:surgery*; D054445:Facial Transplantation; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D014184:Transplantation, Homologous
Allotransplantation; Face reconstruction; Immunosuppression; Microsurgery; Reconstructive microsurgery