Surgical management of complicated and medically refractory inflammatory bowel disease during pregnancy.
OBJECTIVE
The medical management of inflammatory bowel disease (IBD) in pregnancy and the puerperium is well defined. Data on surgical management of complicated IBD in this setting are lacking. This study aimed to determine the optimal surgical strategy for medically refractory IBD during pregnancy and the puerperium.


METHODS
Three databases were systematically reviewed to identify all published series or case reports of women undergoing surgery for Crohn's disease (CD) or ulcerative colitis (UC) while pregnant or during the puerperium.


RESULTS
Thirty-two papers were identified, including 86 patients. Nearly one-fifth (18%) of cases were de novo presentations and intervention was required at all stages of pregnancy. UC refractory to medical treatment and perforated small bowel CD were the commonest indications for surgery. Operations used included colectomy, colectomy with mucous fistula and Turnbull-blowhole colostomy for complicated UC and open or laparoscopic small bowel resection with stoma formation for CD. Surgical intervention during the third trimester universally resulted in the onset of labour. Endoscopic and radiological interventions were rarely employed. In studies after 1980 there was no maternal or foetal mortality but there was an almost 50% preterm delivery rate.


CONCLUSIONS
Surgical management of complicated IBD during pregnancy and the puerperium needs to be tailored to disease severity, the type of complications and foetal status. It should involve gastroenterologists, colorectal surgeons, obstetricians and neonatal specialists in a multidisciplinary manner within a single unit.
Department of Colorectal Surgery, Castlehill Hospital, Cottingham, UK.
S
S
Killeen
Department of Colorectal Surgery, Castlehill Hospital, Cottingham, UK.
J
J
Gunn
Department of Colorectal Surgery, Castlehill Hospital, Cottingham, UK.
J
J
Hartley
D003082:Colectomy / Q000379:methods; D003093:Colitis, Ulcerative / Q000601:surgery*; D003424:Crohn Disease / Q000601:surgery*; D013505:Digestive System Surgical Procedures / Q000379:methods*; D004766:Enterostomy / Q000379:methods; D005260:Female; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000601:surgery; D007421:Intestine, Small / Q000601:surgery; D010535:Laparoscopy; D011183:Postoperative Complications / Q000453:epidemiology*; D049590:Postpartum Period; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D047928:Premature Birth / Q000453:epidemiology*
Crohn's disease; Ulcerative colitis; inflammatory bowel disease; pregnancy; surgery