Molecular Assembly of Polysaccharide-Based Microcapsules and Their Biomedical Applications.
Advanced multifunctional microcapsules have revealed great potential in biomedical applications owing to their tunable size, shape, surface properties, and stimuli responsiveness. Polysaccharides are one of the most acceptable biomaterials for biomedical applications because of their outstanding virtues such as biocompatibility, biodegradability, and low toxicity. Many efforts have been devoted to investigating novel molecular design and efficient building blocks for polysaccharide-based microcapsules. In this Personal Account, we first summarize the common features of polysaccharides and the main principles of the design and fabrication of polysaccharide-based microcapsules, and further discuss their applications in biomedical areas and perspectives for future research.
Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.
Xiyun
X
Feng
National Center for Nanoscience and Technology, Beijing, 100190, P. R. China.
Cuiling
C
Du
Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Colloid, Interface and Chemical Thermodynamics, Institute of Chemistry Chinese Academy of Sciences, Beijing, 100190, P. R. China.|University of Chinese Academy of Sciences, Beijing, 100049, P. R. China.|National Center for Nanoscience and Technology, Beijing, 100190, P. R. China.
Junbai
J
Li
D002214:Capsules; D045744:Cell Line, Tumor; D004337:Drug Carriers / Q000737:chemistry; D065546:Drug Liberation; D006801:Humans; D006860:Hydrogen Bonding; D006863:Hydrogen-Ion Concentration; D011134:Polysaccharides / Q000138:chemical synthesis / Q000737:chemistry* / Q000494:pharmacology
D002214:Capsules; D004337:Drug Carriers; D011134:Polysaccharides
drug delivery; nanostructures; polysaccharides; self-assembly; smart carriers