Zoonotic Transmission of Two New Strains of Human T-lymphotropic Virus Type 4 in Hunters Bitten by a Gorilla in Central Africa.
Molecular screening of 300 at-risk people from Central Africa identified 2 human T-lymphotropic virus (HTLV)-4-infected individuals. A zoonotic origin of infection was suggested, as both individuals reported being severely bitten by a gorilla during hunting activities. One strain was highly divergent and was designated as the HTLV-4 subtype-b prototype.
Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur.|Centre National de la Recherche Scientifique, UMR 3569.|Université Paris Diderot, Cellule Pasteur, France.
Léa
L
Richard
Unité de rétrovirologie, Centre International de Recherches Médicales de Franceville, Gabon.
Augustin
A
Mouinga-Ondémé
Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur.|Centre National de la Recherche Scientifique, UMR 3569.|Faculty of Medicine and Biomedical Sciences, University of Yaounde I.
Edouard
E
Betsem
Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur.|Centre National de la Recherche Scientifique, UMR 3569.
Claudia
C
Filippone
Centre Pasteur du Cameroun, Yaoundé, Cameroon.
Eric
E
Nerrienet
Unité de rétrovirologie, Centre International de Recherches Médicales de Franceville, Gabon.
Mirdad
M
Kazanji
Unité d'Epidémiologie et Physiopathologie des Virus Oncogènes, Institut Pasteur.|Centre National de la Recherche Scientifique, UMR 3569.
Antoine
A
Gessain
D000368:Aged; D000818:Animals; D001733:Bites and Stings / Q000821:virology*; D004279:DNA, Viral / Q000097:blood / Q000235:genetics; D017977:Deltaretrovirus / Q000235:genetics*; D006800:Deltaretrovirus Infections / Q000635:transmission / Q000662:veterinary / Q000821:virology; D005681:Gabon; D006071:Gorilla gorilla / Q000821:virology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015047:Zoonoses / Q000635:transmission / Q000821:virology
D004279:DNA, Viral
Central Africa; HTLV-4; emergence; gorilla; zoonosis