Functional limitation and cognitive impairment among 80+ year old Chinese.
OBJECTIVE
This study examined functional limitation in relation to cognitive impairment among 80+ year old Chinese.


METHODS
Cognitively-intact adults ≥80 years old (n = 5161) came from the 1998 Chinese Longitudinal Healthy Longevity Survey. Cognitive impairment was assessed by Mini-Mental State Examination. Functional limitation was assessed by Katz activities of daily living (ADLs). Cox regressions were performed to examine the relationship between functional limitation in 1998 and cognitive impairment onset during the follow-up period of 1998-2012.


RESULTS
Compared to those without ADLs limitation at baseline, participants with ADLs limitations were 49% more likely to develop cognitive impairment during follow-up. A dose-response relationship was identified - compared to those without ADLs limitation at baseline, those with one, two to five and all six ADLs limitations were 46, 50 and 180% more likely to develop cognitive impairment during follow-up, respectively.


CONCLUSIONS
Baseline functional limitation strongly predicted cognitive impairment incidence in 80+ year old Chinese.
School of Sport Leisure, Recreation and Arts, Shanghai University of Sport, Shanghai, China.
Jiakun
J
Zheng
Soka University, Aliso Viejo, California, USA.
Junyi
J
Liu
Department of Kinesiology and Community Health, College of Applied Health Sciences, University of Illinois at Urbana-Champaign, Champaign, Illinois, USA.
Ruopeng
R
An
D000203:Activities of Daily Living; D000367:Age Factors; D000369:Aged, 80 and over; D000375:Aging / Q000208:ethnology / Q000523:psychology*; D044466:Asian People / Q000523:psychology*; D002681:China / Q000453:epidemiology; D003071:Cognition; D003072:Cognition Disorders / Q000175:diagnosis / Q000208:ethnology / Q000523:psychology*; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006305:Health Status Indicators; D006306:Health Surveys; D006801:Humans; D053208:Kaplan-Meier Estimate; D008137:Longitudinal Studies; D008297:Male; D016016:Proportional Hazards Models; D011569:Psychiatric Status Rating Scales; D012307:Risk Factors; D013997:Time Factors
activities of daily living; aged, 80 and over; memory disorders