Copper-Catalyzed Direct Propargylation of Polyfluoroarenes with Secondary Propargyl Phosphates.
A copper-catalyzed direct propargylation of polyfluoroarenes with secondary propargyl phosphates has been developed. The reaction proceeds under mild reaction conditions with high efficiency and regioselectivity and provides a concise and straightforward method for the synthesis of polyfluoroarylated derivatives of interest in both life and materials science.
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
Yan-Bo
YB
Yu
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
Zhi-Ji
ZJ
Luo
Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences , 345 Lingling Lu, Shanghai 200032, China.
Xingang
X
Zhang