BIM-EL localization: The key to understanding anoikis resistance in inflammatory breast cancer cells.
Inflammatory breast cancer (IBC) is a highly metastatic and rare type of breast cancer, accounting for 2-6% of newly diagnosed breast cancer cases each year. The highly metastatic nature of IBC cells remains poorly understood. Here we describe our recent data regarding the ability of IBC cells to overcome anoikis.
Department of Biological Sciences; Boler-Parseghian Center for Rare and Neglected Diseases; University of Notre Dame ; Notre Dame, IN USA.
Cassandra L
CL
Buchheit
Department of Biological Sciences; Boler-Parseghian Center for Rare and Neglected Diseases; University of Notre Dame ; Notre Dame, IN USA.
Zachary T
ZT
Schafer
BIM-EL; ERK/MAPK; anoikis; cell death; inflammatory breast cancer; receptor tyrosine kinase