title: Infectious diseases in allogeneic haematopoietic stem cell transplantation: prevention and prophylaxis strategy guidelines 2016.
abstract: Infectious complications after allogeneic haematopoietic stem cell transplantation (allo-HCT) remain a clinical challenge. This is a guideline provided by the AGIHO (Infectious Diseases Working Group) of the DGHO (German Society for Hematology and Medical Oncology). A core group of experts prepared a preliminary guideline, which was discussed, reviewed, and approved by the entire working group. The guideline provides clinical recommendations for the preventive management including prophylactic treatment of viral, bacterial, parasitic, and fungal diseases. The guideline focuses on antimicrobial agents but includes recommendations on the use of vaccinations. This is the updated version of the AGHIO guideline in the field of allogeneic haematopoietic stem cell transplantation utilizing methods according to evidence-based medicine criteria.
authors.affiliation: Department of Internal Medicine II, Division of Hematology and Oncology, Division of Infectious Diseases, Universitätsklinikum, Julius Maximilian's University, Oberdürrbacher Str. 6, 97080, Würzburg, Germany. andrew.ullmann@uni-wuerzburg.de.
authors.forename: Andrew J
authors.initials: AJ
authors.lastname: Ullmann
authors.affiliation: Clinic for Hematology, Oncology und Tumor Immunology, Helios Clinic Berlin-Buch, Berlin, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Schmidt-Hieber
authors.affiliation: Department of Hematology/Oncology, University of Freiburg Medical Center, 79106, Freiburg, Germany.
authors.forename: Hartmut
authors.initials: H
authors.lastname: Bertz
authors.affiliation: Department of Internal Medicine II, Division of Hematology and Oncology, Division of Infectious Diseases, Universitätsklinikum, Julius Maximilian's University, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Werner J
authors.initials: WJ
authors.lastname: Heinz
authors.affiliation: Medical Clinic I, Klinikum Frankfurt (Oder), Frankfurt (Oder), Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Kiehl
authors.affiliation: Haematology and Oncology, Stem Cell Transplantation, Palliative Care, University Hospital Greifswald, Greifswald, Germany.
authors.forename: William
authors.initials: W
authors.lastname: Krüger
authors.affiliation: Medizinische Klinik III, Palliativmedizin und interdisziplinäre Onkologie, St. Josefs-Hospital Wiesbaden, Wiesbaden, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Mousset
authors.affiliation: Sindelfingen-Böblingen Clinical Centre, Medical Department I, Division of Hematology and Oncology, Klinikverbund Südwest, Sindelfingen, Germany.
authors.forename: Stefan
authors.initials: S
authors.lastname: Neuburger
authors.affiliation: Medical Oncology, AMO MVZ, Wolfsburg, Germany.
authors.forename: Silke
authors.initials: S
authors.lastname: Neumann
authors.affiliation: Hematology, Oncology and Tumorimmunology, Charité University Medicine Berlin, Campus Virchow Klinikum, Berlin, Germany.
authors.forename: Olaf
authors.initials: O
authors.lastname: Penack
authors.affiliation: Department of Internal Medicine IV, University Hospital RWTH Aachen, Aachen, Germany.
authors.forename: Gerda
authors.initials: G
authors.lastname: Silling
authors.affiliation: Department I of Internal Medicine, German Centre for Infection Research, Partner-site: Bonn-Cologne, University Hospital of Cologne, Cologne, Germany.
authors.forename: Jörg Janne
authors.initials: JJ
authors.lastname: Vehreschild
authors.affiliation: Department of Internal Medicine II, Division of Hematology and Oncology, Division of Infectious Diseases, Universitätsklinikum, Julius Maximilian's University, Oberdürrbacher Str. 6, 97080, Würzburg, Germany.
authors.forename: Hermann
authors.initials: H
authors.lastname: Einsele
authors.affiliation: Department of Hematology, Oncology and Palliative Care, Klinikum Ernst von Bergmann, Potsdam, Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Maschmeyer
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control*; D005858:Germany; D006405:Hematology / Q000458:organization & administration; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008495:Medical Oncology / Q000458:organization & administration; D009181:Mycoses / Q000209:etiology / Q000517:prevention & control*; D010272:Parasitic Diseases / Q000209:etiology / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D012955:Societies, Medical; D014184:Transplantation, Homologous; D014611:Vaccination / Q000379:methods; D014777:Virus Diseases / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000890:Anti-Infective Agents
keywords: Bacteria; Fungal; Infections; Viral