title: Sinonasal spindle cell carcinoma presenting with bilateral visual loss: A case report and review of the literature.
abstract: Spindle cell carcinoma (SpCC) is a rare variant of squamous cell carcinoma (SCC). SpCC of sinonasal origin is relatively rare and more aggressive than normal SCC. It most commonly involves the maxillary sinus, and rarely the sphenoid sinus. The present study reports a case of sphenoid sinus SpCC presenting with bilateral visual loss. Following endoscopic sinus decompression surgery, the patient was referred to the Oncology Department for a staging workup, and subsequently received concurrent chemoradiotherapy; however, the vision of the patient was not recovered, despite treatment. To the best of our knowledge, this is the first reported case of synchronous inverted papilloma of the sphenoid sinus and SpCC presenting with optic nerve compression.
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei 110, Taiwan, R.O.C.
authors.forename: Tsung-Wei
authors.initials: TW
authors.lastname: Liu
authors.affiliation: Department of Otolaryngology, Taipei Medical University Hospital, Taipei 110, Taiwan, R.O.C.; Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei 110, Taiwan, R.O.C.
authors.forename: Shih-Han
authors.initials: SH
authors.lastname: Hung
authors.affiliation: Department of Otolaryngology - Head and Neck Surgery, Shuang Ho Hospital, Taipei Medical University, Taipei 110, Taiwan, R.O.C.; Department of Otolaryngology, School of Medicine, Taipei Medical University, Taipei 110, Taiwan, R.O.C.
authors.forename: Po-Yueh
authors.initials: PY
authors.lastname: Chen
keywords: head and neck; sinonasal; spindle cell carcinoma; squamous cell carcinoma