title: Multi-Nutrient Dietary Intervention Approach to the Management of Alzheimer's Disease - A Mini-Review.
abstract: Alzheimer's disease (AD) is currently the most common incurable forms of dementia. The number of people affected by this disease is expected to grow rapidly in the next decades due to the present demographic changes. Since the pharmacological treatment of AD is quite costly, researchers try to look for alternative treatments for patients suffering from AD. One of such nonpharmacological approaches is nutritional intervention. The purpose of this minireview is to explore the issue of multi-nutrient intervention in the management of AD with special focus on medical foods and Mediterranean diet. The methods include a method of literature review of available sources, and a method of comparison of different research studies analyzing this topic. The findings of this review study indicate that multi-nutrient intervention seem to bring many benefits for AD patients such as the delay of cognitive decline, non-invasive and less costly treatment or none or fewer side effects. In addition, to minimize the risk of AD, a multi-factorial healthy lifestyle approach should be implemented by people already at their mid-life.
authors.forename: Blanka
authors.initials: B
authors.lastname: Klimova
authors.affiliation: Biomedical Research Centrum, University Hospital Hradec Kralove, Hradec Kralove, Rokitanskeho 62, 50003, Hradec Kralove, Czech Republic. kamil.kuca@fnhk.cz.
authors.forename: Kamil
authors.initials: K
authors.lastname: Kuca
mesh_terms: D000544:Alzheimer Disease / Q000178:diet therapy*; D004035:Diet Therapy / Q000379:methods*; D019468:Disease Management; D006801:Humans