title: Risk Factors for Thyroid Cancer: A Hospital-Based Case-Control Study in Korean Adults.
abstract: OBJECTIVE
  Although the incidence of thyroid cancer in Korea has rapidly increased over the past decade, few studies have investigated its risk factors. This study examined the risk factors for thyroid cancer in Korean adults.
  
  
  METHODS
  The study design was a hospital-based case-control study. Between August 2002 and December 2011, a total of 802 thyroid cancer cases out of 34,211 patients screened from the Cancer Screenee. Cohort of the National Cancer Center in South Korea were included in the analysis. A total of 802 control cases were selected from the same cohort, and matched individually (1:1) by age (±2 years) and area of residence for control group 1 and additionally by sex for control group 2.
  
  
  RESULTS
  Multivariate conditional logistic regression analysis using the control group 1 showed that females and those with a family history of thyroid cancer had an increased risk of thyroid cancer, whereas ever-smokers and those with a higher monthly household income had a decreased risk of thyroid cancer. On the other hand, the analysis using control group 2 showed that a family history of cancer and alcohol consumption were associated with a decreased risk of thyroid cancer, whereas higher body mass index (BMI) and family history of thyroid cancer were associated with an increased risk of thyroid cancer.
  
  
  CONCLUSIONS
  These findings suggest that females, those with a family history of thyroid cancer, those with a higher BMI, non-smokers, non-drinkers, and those with a lower monthly household income have an increased risk of developing thyroid cancer.
authors.affiliation: Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.|Center for Cancer Prevention and Detection, National Cancer Center Hospital, National Cancer Center, Goyang, Korea.|Department of Family Medicine, National Cancer Center Hospital, National Cancer Center, Goyang, Korea.|Molecular Epidemiology Branch, Research Institute, National Cancer Center, Goyang, Korea.
authors.forename: Seung-Kwon
authors.initials: SK
authors.lastname: Myung
authors.affiliation: Center for Cancer Prevention and Detection, National Cancer Center Hospital, National Cancer Center, Goyang, Korea.|Department of Radiology, Center for Diagnostic Oncology, National Cancer Center Hospital, National Cancer Center, Goyang Korea.
authors.forename: Chan Wha
authors.initials: CW
authors.lastname: Lee
authors.affiliation: Molecular Epidemiology Branch, Research Institute, National Cancer Center, Goyang, Korea.
authors.forename: Jeonghee
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, Goyang, Korea.|Molecular Epidemiology Branch, Research Institute, National Cancer Center, Goyang, Korea.
authors.forename: Jeongseon
authors.initials: J
authors.lastname: Kim
authors.affiliation: School of Nursing, Shinhan University, Dongducheon, Korea.
authors.forename: Hyeon Suk
authors.initials: HS
authors.lastname: Kim
mesh_terms: D000428:Alcohol Drinking; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D016017:Odds Ratio; D011159:Population Surveillance; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012907:Smoking; D012959:Socioeconomic Factors; D013964:Thyroid Neoplasms / Q000453:epidemiology* / Q000209:etiology*
keywords: Alcohols; Case-control studies; Risk factors; Smoking; Thyroid neoplasms