title: Safety and efficacy of flow re-direction endoluminal device (FRED) in the treatment of cerebral aneurysms: a single center experience.
abstract: Experience with the endovascular treatment of cerebral aneurysms by the Flow Re-Direction Endoluminal Device (FRED) is still limited. The aim of this study is to discuss the results and complications of this new flow diverter device (FDD).
  
  
  
  Between November 2013 and April 2015, 20 patients (15 female and five male) harboring 24 cerebral aneurysms were treated with FRED FDD in a single center.
  
  
  
  Complete occlusion was obtained in 20/24 aneurysms (83 %) and partial occlusion in four (17 %). Intraprocedural technical complication occurred in one case (4 %) and post-procedural complications in three (12 %). None reported neurological deficits (mRS = 0). All FRED were patent at follow-up. No early or delayed aneurysm rupture, no subarachnoid (SAH) or intraparenchymal hemorrhage (IPH) no ischemic complications and no deaths occurred.
  
  
  
  Endovascular treatment with FRED FDD is a safe treatment for unruptured cerebral aneurysms, resulting in a high rate of occlusion. The FRED is substantially equivalent to the other known FDDs, which show similar functions and technical profiles.
authors.affiliation: Department of Advanced Biomedical Sciences, Unit of Interventional Neuroradiology, "Federico II" University, Via S. Pansini, 5, 80131, Naples, Italy. frabriga@unina.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Briganti
authors.affiliation: Department of Advanced Biomedical Sciences, "Federico II", Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Leone
authors.affiliation: Department of Advanced Biomedical Sciences, "Federico II", Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Ugga
authors.affiliation: Department of Advanced Biomedical Sciences, Unit of Interventional Neuroradiology, "Federico II" University, Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Mariano
authors.initials: M
authors.lastname: Marseglia
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, "Federico II" University, Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Solari
authors.affiliation: Department of Advanced Biomedical Sciences, "Federico II", Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Ferdinando
authors.initials: F
authors.lastname: Caranci
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, "Federico II" University, Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mariniello
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, "Federico II" University, Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: Maiuri
authors.affiliation: Division of Neurosurgery, Department of Neurosciences, Reproductive and Odontostomatological Sciences, "Federico II" University, Via S. Pansini, 5, 80131, Naples, Italy.
authors.forename: Paolo
authors.initials: P
authors.lastname: Cappabianca
mesh_terms: D000328:Adult; D000368:Aged; D057510:Endovascular Procedures / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D010043:Outcome and Process Assessment, Health Care
keywords: Endovascular treatment; FRED; Flow diverter devices; Intracranial aneurysm