title: Coumarin-decorated Schiff base hydrolysis as an efficient driving force for the fluorescence detection of water in organic solvents.
abstract: A coumarin based Schiff base was found to be an excellent indicator of moisture, via rapid in situ hydrolysis. A structure-relationship examination of a small library of Schiff bases revealed the critical importance of hydrogen bond acceptors in close proximity to the imine bond, and this observation was further supported by theoretical calculations as well as the solid state structure analysis. The most sensitive compound demonstrated a limit of detection and quantification of 0.18% and 0.54% v/v water in DMSO, respectively.
authors.affiliation: Department of Chemistry, Korea University, Seoul 136-701, Korea. jongskim@korea.ac.kr.
authors.forename: Won Young
authors.initials: WY
authors.lastname: Kim
authors.affiliation: Department of Chemistry, Sungkyunkwan University, Suwon 16419, Korea. jinylee@skku.edu.
authors.forename: Hu
authors.initials: H
authors.lastname: Shi
authors.affiliation: Department of Chemistry, Korea University, Seoul 136-701, Korea. jongskim@korea.ac.kr.
authors.forename: Hyo Sung
authors.initials: HS
authors.lastname: Jung
authors.affiliation: Department of Chemistry, Sungkyunkwan University, Suwon 16419, Korea. jinylee@skku.edu.
authors.forename: Daeheum
authors.initials: D
authors.lastname: Cho
authors.affiliation: Department of Chemistry, Korea University, Seoul 136-701, Korea. jongskim@korea.ac.kr.
authors.forename: Peter
authors.initials: P
authors.lastname: Verwilst
authors.affiliation: Department of Chemistry, Sungkyunkwan University, Suwon 16419, Korea. jinylee@skku.edu.
authors.forename: Jin Yong
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Department of Chemistry, Korea University, Seoul 136-701, Korea. jongskim@korea.ac.kr.
authors.forename: Jong Seung
authors.initials: JS
authors.lastname: Kim
mesh_terms: D003374:Coumarins / Q000737:chemistry*; D004121:Dimethyl Sulfoxide / Q000737:chemistry*; D005453:Fluorescence; D006868:Hydrolysis; D012545:Schiff Bases / Q000737:chemistry*; D012997:Solvents / Q000737:chemistry*; D014867:Water / Q000032:analysis*
chemical_list: D003374:Coumarins; D012545:Schiff Bases; D012997:Solvents; D014867:Water; D004121:Dimethyl Sulfoxide