title: Incidental focal18F-FDG uptake in the frontal process of the maxilla on PET/CT: prevalence and clinical significance.
abstract: OBJECTIVE
  We investigated the prevalence and clinical significance of incidental focal18F-FDG uptake in the frontal process of the maxilla, mimicking malignancy on PET/CT.
  
  
  METHODS
  From a total of 32,834 patients who underwent18F-FDG PET/CT, patients with focal uptake in the frontal process of the maxilla were selected by a database search. For those patients, medical records including relevant imaging studies were reviewed.
  
  
  RESULTS
  Thirty-nine patients (0.12 %) demonstrated focal uptake on PET/CT. On CT of PET/CT, all lesions showed ground-glass attenuation with or without bony expansion, consistent with fibrous dysplasia. When comparing previous PET/CT, follow-up PET/CT, and CT, a significant difference in degree of18F-FDG uptake was noted, with no associated change in the size of maxillary lesions. There were no patients who had symptoms or signs related to maxillary lesions during follow-up.
  
  
  CONCLUSIONS
  Focal18F-FDG uptake in the frontal process of the maxilla is a rare, incidental, and persistent finding with variable uptake and can represent a benign condition.
authors.affiliation: Department of Radiology, Soonchunhyang University Hospital, 59 Daesagwan-ro, Yongsan-gu, Seoul, 04401, Republic of Korea.
authors.forename: Soo Bin
authors.initials: SB
authors.lastname: Park
authors.affiliation: Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea. jynm.choi@samsung.com.
authors.forename: Joon Young
authors.initials: JY
authors.lastname: Choi
authors.affiliation: Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
authors.forename: Hyung-Jin
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Radiology, Kangnam Sacred Heart Hospital, Hallym University School of Medicine, Shingil-ro, Yeongdeungpo-gu, Seoul, 07441, Republic of Korea.
authors.forename: Hye Jeong
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
authors.forename: Kyung-Han
authors.initials: KH
authors.lastname: Lee
authors.affiliation: Department of Nuclear Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
authors.forename: Byung-Tae
authors.initials: BT
authors.lastname: Kim
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001692:Biological Transport; D005189:False Positive Reactions; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000378:metabolism*; D006801:Humans; D008297:Male; D008437:Maxilla / Q000000981:diagnostic imaging / Q000378:metabolism*; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography
chemical_list: D019788:Fluorodeoxyglucose F18
keywords: 18F-fluorodeoxyglucose; Fibrous dysplasia; Maxilla; PET/CT