title: Infants with Trisomy 18 and Complex Congenital Heart Defects Should Not Undergo Open Heart Surgery.
abstract: Aggressive medical and surgical interventions have not been clearly demonstrated to improve survival in neonates with trisomy 18; there are no data that demonstrates improved quality of life for these children after these interventions; and these interventions are clearly associated with significant morbidity, resource allocation, and cost.
authors.affiliation: Eric M. Graham, M.D., is a physician in the Division of Pediatric Cardiology at the Medical University of South Carolina.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Graham
mesh_terms: D013504:Cardiovascular Surgical Procedures / Q000941:ethics*; D002887:Chromosomes, Human, Pair 18; D006330:Heart Defects, Congenital / Q000601:surgery*; D006801:Humans; D007223:Infant; D011788:Quality of Life; D014314:Trisomy; D000073842:Trisomy 18 Syndrome