title: Roles of Biogenic Amines in Intestinal Signaling.
abstract: Biogenic amines in the gastrointestinal tract are important metabolites of dietary protein and amino acids with the help of gut digestive enzymes and microbes, which play a crucial role in the regulation of intestinal functions, including digestion, absorption, and local immunity. However, high concentrations of biogenic amines can induce adverse reactions and are harmful to animal's health. Therefore, it is crucial to have a clear understanding of how different biogenic amines interact with a body's intestinal function signaling pathways and to monitor the content of biogenic amines in the gastrointestinal tract. And in turn, the proper concentration of dietary protein and balanced amino acids for humans and livestock could be given. Though numerous methods have been developed and improved for the detection of biogenic amines in foods or wines much less attention has been paid directly to the determination of amine levels in the gastrointestinal tract. In this article, we mainly focus on the interaction of amines with the intestinal function signaling pathway and the broad impacts on animal physiology, and our modified method to accurately and quickly detect the biogenic amines in the digesta of an animal intestine.
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Peixin
authors.initials: P
authors.lastname: Fan
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Peixia
authors.initials: P
authors.lastname: Song
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Linsen
authors.initials: L
authors.lastname: Li
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Chang
authors.initials: C
authors.lastname: Huang
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Jingshu
authors.initials: J
authors.lastname: Chen
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Wenjun
authors.initials: W
authors.lastname: Yang
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, No 2. Yuanmingyuan West Road, Beijing, 100193. China.
authors.forename: Shiyan
authors.initials: S
authors.lastname: Qiao
authors.affiliation: Department of Animal Science, Texas A&M University, College Station 77843. United States.
authors.forename: Guoyao
authors.initials: G
authors.lastname: Wu
authors.affiliation: Department of Animal Science, Oklahoma State University, Stillwater, Oklahoma 74078. United States.
authors.forename: Guolong
authors.initials: G
authors.lastname: Zhang
authors.affiliation: State Key Lab of Animal Nutrition, China Agricultural University, Beijing, 100193. China.
authors.forename: Xi
authors.initials: X
authors.lastname: Ma
mesh_terms: D000824:Animal Nutritional Physiological Phenomena; D000818:Animals; D001679:Biogenic Amines / Q000032:analysis / Q000378:metabolism*; D002851:Chromatography, High Pressure Liquid / Q000379:methods; D004044:Dietary Proteins / Q000378:metabolism; D041981:Gastrointestinal Tract / Q000378:metabolism*; D007413:Intestinal Mucosa / Q000378:metabolism; D015398:Signal Transduction
chemical_list: D001679:Biogenic Amines; D004044:Dietary Proteins
keywords: Biogenic amines; HPLC; gastrointestinal tract; modulation; signaling pathway