title: [Endogenous neural stem cell mobilization with intraventricular growth factor administration].
abstract: It is now well recognized that new neurons are continuously generated in the specific regions of the adult brain across all mammalian species including humans. Now the cumulative findings demonstrate that this capacity for neurogenesis at the adult stage is associated with self-repair mechanisms in the damaged brain. Then, one of the main reasons that in vivo growth factor treatment is worth studying is the expectation that such treatment would promote the regeneration of neurons after stroke. Here we show the cumulative evidence that this approach is feasible as one of the brain repair therapies.
authors.forename: Hirofumi
authors.initials: H
authors.lastname: Nakatomi
authors.forename: Takashi
authors.initials: T
authors.lastname: Ochi
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Saito
mesh_terms: D000818:Animals; D002465:Cell Movement / Q000187:drug effects*; D004195:Disease Models, Animal; D006801:Humans; D057967:Infusions, Intraventricular; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage* / Q000494:pharmacology; D009416:Nerve Regeneration / Q000187:drug effects; D058953:Neural Stem Cells / Q000502:physiology*; D055495:Neurogenesis / Q000187:drug effects; D051381:Rats; D020521:Stroke / Q000473:pathology* / Q000503:physiopathology / Q000628:therapy
chemical_list: D036341:Intercellular Signaling Peptides and Proteins