title: Near Full-Length Genome Identification of a Novel HIV-1 Unique (B/C) Recombinant Isolate in Sichuan, China.
abstract: A novel HIV-1 unique recombinant virus (XC2014EU20) was identified. It was isolated from an HIV-positive man who was infected through heterosexual sex in Sichuan, China. The near full-length genome analyses showed that the novel recombinant was composed of three subtype B regions in a subtype C backbone. Different from the other circulating recombinant forms and unique recombinant forms, six recombinant breakpoints of XC2014EU20 with seven fragments were observed in the pol, vpu, and nef genes, respectively. The emergence of B/C recombinant strain indicated the increasing complexity of the HIV-1 epidemic in Sichuan, China.
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .
authors.forename: Liying
authors.initials: L
authors.lastname: Ma
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .
authors.forename: Weisi
authors.initials: W
authors.lastname: Xu
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .
authors.forename: Fan
authors.initials: F
authors.lastname: Li
authors.affiliation: 2 Sichuan Center for Disease Control and Prevention , Chengdu, People's Republic of China .
authors.forename: Shu
authors.initials: S
authors.lastname: Liang
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .
authors.forename: Yi
authors.initials: Y
authors.lastname: Feng
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .
authors.forename: Yiming
authors.initials: Y
authors.lastname: Shao
authors.affiliation: 1 State Key Laboratory of Infectious Disease Prevention and Control, Division of Treatment and Care, National Center for AIDS/STD Control and Prevention, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Chinese Center for Disease Control and Prevention , Beijing, People's Republic of China .|3 Clinical and Research Center of Infectious Diseases, Beijing Ditan Hospital, Capital Medical University , Beijing, People's Republic of China .|4 Clinical Center for AIDS, Capital Medical University , Beijing, People's Republic of China .
authors.forename: Fujie
authors.initials: F
authors.lastname: Zhang
mesh_terms: D000328:Adult; D002681:China; D016679:Genome, Viral; D005838:Genotype; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000145:classification / Q000235:genetics* / Q000302:isolation & purification*; D006801:Humans; D008297:Male; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA
keywords: HIV-1 recombinant; heterosexual; near full-length genome