title: Epidemiological trends of hormone-related cancers in Slovenia.
abstract: The incidence of hormone-related cancers tends to be higher in the developed world than in other countries. In Slovenia, six hormone-related cancers (breast, ovarian, endometrial, prostate, testicular, and thyroid) account for a quarter of all cancers. Their incidence goes up each year, breast and prostate cancer in particular. The age at diagnosis is not decreasing for any of the analysed cancer types. The risk of breast cancer is higher in the western part of the country, but no differences in geographical distribution have been observed for other hormone-related cancers. Furthermore, areas polluted with endocrine-disrupting chemicals that affect hormone balance such as PCBs, dioxins, heavy metals, and pesticides, do not seem to involve a greater cancer risk. We know little about how many cancers can be associated with endocrine disruptors, as there are too few reliable exposure studies to support an association.
authors.forename: Vesna
authors.initials: V
authors.lastname: Zadnik
authors.forename: Mateja
authors.initials: M
authors.lastname: Krajc
mesh_terms: D001943:Breast Neoplasms / Q000453:epidemiology / Q000209:etiology*; D004147:Dioxins / Q000009:adverse effects; D052244:Endocrine Disruptors / Q000009:adverse effects*; D016889:Endometrial Neoplasms / Q000453:epidemiology / Q000209:etiology*; D004781:Environmental Exposure / Q000009:adverse effects; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D019216:Metals, Heavy / Q000009:adverse effects; D010051:Ovarian Neoplasms / Q000453:epidemiology / Q000209:etiology*; D010575:Pesticides / Q000009:adverse effects; D011078:Polychlorinated Biphenyls / Q000009:adverse effects; D011471:Prostatic Neoplasms / Q000453:epidemiology / Q000209:etiology*; D012307:Risk Factors; D017524:Slovenia / Q000453:epidemiology; D013736:Testicular Neoplasms / Q000453:epidemiology / Q000209:etiology*; D013964:Thyroid Neoplasms / Q000453:epidemiology / Q000209:etiology*
chemical_list: D004147:Dioxins; D052244:Endocrine Disruptors; D019216:Metals, Heavy; D010575:Pesticides; D011078:Polychlorinated Biphenyls