title: Anger and stroke: a potential association that deserves serious consideration.
abstract: OBJECTIVE
  To assess the relationship between states of anger and stroke.
  
  
  METHODS
  Systematic review of the literature.
  
  
  RESULTS
  In total, 21 papers were selected for the systematic review of data published on the subject of anger and stroke. A state of anger may be a risk factor for stroke, as well as a consequence of brain lesions affecting specific areas that are caused by a stroke. Scales to assess anger varied among authors. There was no consensus regarding the area of brain lesions that might lead to a state of anger. Although some authors agreed that lesions on the right side led to angrier behaviour, others found that lesions on the left side were more relevant to anger. Likewise, there was no consensus regarding the prevalence of anger pre or post-stroke. Some authors did not even find that these two conditions were related.
  
  
  CONCLUSIONS
  Although most authors have accepted that there is a relationship between anger and stroke, studies with uniform methodology need to be conducted if this association is to be properly evaluated and understood.
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Pedro Banho
authors.initials: PB
authors.lastname: Rosa
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Bruna
authors.initials: B
authors.lastname: Orquiza
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Filipe Benetti
authors.initials: FB
authors.lastname: Rocha
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Rafael Werlanger
authors.initials: RW
authors.lastname: Donadel
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Rodrigo Pizzolante
authors.initials: RP
authors.lastname: Diniz
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Tamara Maia Nestlehner
authors.initials: TM
authors.lastname: Beloni
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Joara Turi
authors.initials: JT
authors.lastname: Aniceto
authors.affiliation: Department of Neurology,Medical School,Universidade Metropolitana de Santos,SP,Brazil.
authors.forename: Yara Dadalti
authors.initials: YD
authors.lastname: Fragoso
mesh_terms: D000786:Anger; D001921:Brain / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D012307:Risk Factors; D020521:Stroke / Q000453:epidemiology* / Q000523:psychology*
keywords: anger; brain lesion; cerebrovascular disease; emotions; stroke