title: Surgical Outcome of Endoscopic Endonasal Surgery for Non-Functional Pituitary Adenoma by a Team of Neurosurgeons and Otolaryngologists Adenoma by a Team of Neurosurgeons and Otolaryngologists.
abstract: OBJECTIVE
  This study aimed to assess the efficacy of endoscopic endonasal surgery, conducted by a team of neurosurgeons and otolaryngologists.
  
  
  METHODS
  We studied 40 patients who were undergoing surgery for primary non-functional pituitary adenomas with Knosp grades 1 to 3, at Keio University Hospital between 2005 and 2012. We compared the endoscopic endonasal transsphenoidal approach (team-eTSS; T-eTSS), with a microscopic transsphenoidal approach (mTSS). Analyses were conducted for differences between the two groups in tumor resection rates, operating durations, and complications from the non-functional pituitary adenomas. We also compared the heminostril and binostril approaches for T-eTSS.
  
  
  RESULTS
  Tumor resection rates were higher when the surgeries were conducted by T-eTSS than mTSS. In particular, when the maximum tumor diameter was more than 25 mm, resection rates were significantly higher for T-eTSS than for mTSS. There were no unexpected complications in either group. There was no significant difference in resection rates between the heminostril and binostril approaches when T-eTSS was performed.
  
  
  CONCLUSIONS
  T-eTSS is an efficacious surgical option for non-functional pituitary adenomas, particularly when the adenoma is of large size. Benefits of the heminostril approach are evident.
authors.affiliation: Keio University School of Medicine, Department of Neurosurgery, Shinjuku, Tokyo, Japan.
authors.forename: Ryogo
authors.initials: R
authors.lastname: Kikuchi
authors.forename: Masahiro
authors.initials: M
authors.lastname: Toda
authors.forename: Toshiki
authors.initials: T
authors.lastname: Tomita
authors.forename: Kaoru
authors.initials: K
authors.lastname: Ogawa
authors.forename: Kazunari
authors.initials: K
authors.lastname: Yoshida
mesh_terms: D000236:Adenoma / Q000601:surgery*; D000328:Adult; D000368:Aged; D004724:Endoscopy / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D000069471:Neurosurgeons; D009666:Nose / Q000601:surgery*; D000072220:Otolaryngologists; D010348:Patient Care Team; D010911:Pituitary Neoplasms / Q000601:surgery*; D012189:Retrospective Studies; D016896:Treatment Outcome