title: Fetal intracranial immature teratoma: presentation of a case and a systematic review of the literature.
abstract: OBJECTIVE
  To describe a case diagnosed with intracranial teratoma in week 32 of gestation, as well as review of the literature in order to discern the appropriate treatment method and general prognosis of this anomaly.
  
  
  METHODS
  A literature search was performed on the prenatal diagnosis of congenital intracranial teratomas in MEDLINE, EMBASE, Cochrane library data bases. Evaluated in this review are parameters such as time of prenatal diagnosis, associated pathology, size of tumors, method of terminating pregnancy, perinatal outcome and histological study of the tumor.
  
  
  RESULTS
  A total of 49 cases were found, of which 12 were finished gestation, 28 cesarean section was performed and only nine had vaginal delivery. All died in the neonatal period except in three cases with intrauterine death after diagnosis.
  
  
  CONCLUSIONS
  As the incidence of intracranial immature teratomas is very low and the prognosis is poor, their prenatal diagnosis and obstetric management present a great challenge for the planning of a follow-up and treatment of the disease in accordance with the preferences of the parents.
authors.affiliation: a Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology.
authors.forename: M
authors.initials: M
authors.lastname: Robles Fradejas
authors.affiliation: a Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology.
authors.forename: I
authors.initials: I
authors.lastname: Gonzalo García
authors.affiliation: a Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology.
authors.forename: A C
authors.initials: AC
authors.lastname: De Las Casas Quispe
authors.affiliation: a Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology.
authors.forename: A
authors.initials: A
authors.lastname: Martin García
authors.affiliation: b Department of Anatomic Pathology , and.
authors.forename: M I
authors.initials: MI
authors.lastname: García Higuera
authors.affiliation: c Neonatology Unit, Department of Pediatrics Burgos University Hospital , Burgos , Spain.
authors.forename: M
authors.initials: M
authors.lastname: Rodriguez Minguélez
authors.affiliation: a Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology.
authors.forename: J
authors.initials: J
authors.lastname: Martínez-Guisasola
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D002585:Cesarean Section; D017809:Fatal Outcome; D005260:Female; D005315:Fetal Diseases / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D007231:Infant, Newborn; D011247:Pregnancy; D013724:Teratoma / Q000151:congenital* / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery; D016216:Ultrasonography, Prenatal
keywords: Congenital brain tumors; fetal tumor; intracranial immature teratoma; prenatal diagnosis