title: The effect of long-term use of intranasal steroids on intraocular pressure.
abstract: Long-term use of topical nasal steroids (especially older generation steroids) has been shown to elevate intraocular pressure (IOP), but newer intranasal steroids are thought to have a minimal effect on IOP because of their low bioavailability. This study aimed to investigate alterations in IOP with two commonly used intranasal steroids for a 6-month period of time. One-hundred allergic rhinitis patients, divided equally into two groups, used mometasone furoate and fluticasone furoate intranasal steroids for 6 months. IOPs were measured before treatment and repeated at the 3rd, 6th, 12th, and 24th weeks of treatment. The IOPs of the groups were then compared. No statistically significant alteration was observed between the groups during the treatment time period. It was found that new generation intranasal steroids can be used safely, and there may not be an increased risk of IOP elevation in prolonged use in normal healthy people.
authors.affiliation: Department of Ophthalmology, Adıyaman University Research and Education Hospital, Adıyaman, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Şimşek
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey.
authors.forename: Cem
authors.initials: C
authors.lastname: Bayraktar
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Doğan
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Karataş
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Adıyaman University Research and Education Hospital, Adıyaman, Turkey.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Sarıkaya
keywords: allergic rhinitis; intraocular pressure; nasal steroids; prolonged use