title: Tunable P-Chiral Bisdihydrobenzooxaphosphole Ligands for Enantioselective Hydroformylation.
abstract: Air-stable and tunable chiral bisdihydrobenzooxaphosphole ligands (BIBOPs) were employed in rhodium-catalyzed asymmetric hydroformylation of various terminal olefins with excellent conversions (>99%), moderate-to-excellent enantioselectivities (up to 95:5 er), and branched to linear ratios (b:l) of up to 400.
authors.affiliation: Department of Chemistry and Chemical Biology and Department of Medicinal Chemistry, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United States.
authors.forename: Renchang
authors.initials: R
authors.lastname: Tan
authors.affiliation: Department of Chemistry and Chemical Biology and Department of Medicinal Chemistry, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United States.
authors.forename: Xin
authors.initials: X
authors.lastname: Zheng
authors.affiliation: Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc. , 900 Ridgebury Road, Ridgefield, Connecticut 06877, United States.
authors.forename: Bo
authors.initials: B
authors.lastname: Qu
authors.affiliation: Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc. , 900 Ridgebury Road, Ridgefield, Connecticut 06877, United States.
authors.forename: C Avery
authors.initials: CA
authors.lastname: Sader
authors.affiliation: Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc. , 900 Ridgebury Road, Ridgefield, Connecticut 06877, United States.
authors.forename: Keith R
authors.initials: KR
authors.lastname: Fandrick
authors.affiliation: Chemical Development, Boehringer Ingelheim Pharmaceuticals, Inc. , 900 Ridgebury Road, Ridgefield, Connecticut 06877, United States.
authors.forename: Chris H
authors.initials: CH
authors.lastname: Senanayake
authors.affiliation: Department of Chemistry and Chemical Biology and Department of Medicinal Chemistry, Rutgers, The State University of New Jersey , Piscataway, New Jersey 08854, United States.
authors.forename: Xumu
authors.initials: X
authors.lastname: Zhang