title: Correlation of Vitreomacular Traction with Foveal Thickness, Subfoveal Choroidal Thickness, and Vitreomacular/Foveal Angle.
abstract: To investigate the structure of vitreomacular traction (VMT), specifically, if a correlation exists between 1) the VMT type/grade and the central foveal thickness (CFT) and subfoveal and adjacent choroidal thickness, 2) the vitreomacular/foveal angle (VMFA) and the CFT and subfoveal and adjacent choroidal thickness, and 3) the diameter of vitreomacular adhesion (VMA) and CFT and subfoveal and adjacent choroidal thickness.
  
  
  
  Retrospective, multicenter image analysis study. We analyzed raster scans of the macula taken with spectral-domain optical coherence tomography (SD-OCT) of 61 eyes of 55 patients with VMT. Conventional scans of the vitreoretinal interface were analyzed to measure CFT and the degree of VMFA. Enhanced depth imaging (EDI) scans were analyzed to measure the choroidal thickness in the macula. The multivariate test of means and the t-test were used for statistical comparisons.
  
  
  
  There was no statistically significant difference in CFT between focal vs broad and concurrent vs isolated type VMT. Central (p = 0.009), nasal (p = 0.004), and temporal (p = 0.007) subfoveal choroidal thickness was significantly higher in broad VMT compared to focal VMT. There was difference in both CFT (p = 0.035) and central (p = 0.005), nasal (p = 0.01), and temporal (p = 0.001) choroidal thickness between moderate and severe VMT. There was a correlation between VMFA and CFT, where a wider angle was associated with increased CFT (p = 0.026). The broader VMA was associated with increased central subfoveal (p = 0.032), nasal (p = 0.05), and temporal (p = 0.01) choroidal thickness.
  
  
  
  Eyes with broad VMT have thicker choroid than eyes with focal VMT, which have a more open vitreomacular angle. The angle of VMT is related to distinct CFTs.
authors.affiliation: a King Khaled Eye Specialist Hospital , Riyadh , Saudi Arabia.
authors.forename: Igor
authors.initials: I
authors.lastname: Kozak
authors.affiliation: b Ophthalmological Unit, Department of Clinical Sciences and Community Health , Ca' Granda Foundation-Ospedale Maggiore Policlinico, University of Milan , Milan , Italy.|c Genentech Inc ., South San Francisco , CA , USA.
authors.forename: Giulio
authors.initials: G
authors.lastname: Barteselli
authors.affiliation: d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
authors.forename: Yasir J
authors.initials: YJ
authors.lastname: Sepah
authors.affiliation: d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
authors.forename: Mohammad Ali
authors.initials: MA
authors.lastname: Sadiq
authors.affiliation: e Maurer College of Public Health at the University of Nebraska Medical Center Omaha , NE , USA.
authors.forename: Robin
authors.initials: R
authors.lastname: High
authors.affiliation: d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
authors.forename: Diana V
authors.initials: DV
authors.lastname: Do
authors.affiliation: d Truhlsen Eye Institute, University of Nebraska Medical Center , Omaha , NE , USA.
authors.forename: Quan Dong
authors.initials: QD
authors.lastname: Nguyen
mesh_terms: D005260:Female; D005584:Fovea Centralis / Q000473:pathology*; D006801:Humans; D008266:Macula Lutea / Q000473:pathology; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence / Q000379:methods*; D014792:Visual Acuity; D014822:Vitreous Body / Q000473:pathology* / Q000601:surgery; D020255:Vitreous Detachment / Q000473:pathology / Q000601:surgery*
keywords: Choroidal thickness; enhanced depth imaging; spectral domain optical coherence tomograph; vitreomacular traction