title: Evaluation of factors affecting adherence to asthma controller therapy in chest clinics in a sub-Saharan African setting: a cross-sectional study.
abstract: BACKGROUND
  Adherence to controller therapy in asthma is a major concern during the management of the disease.
  
  
  OBJECTIVE
  To determine the adherence rate and identify the predictors of low adherence to asthma controller therapy.
  
  
  METHODS
  A cross-sectional study including asthma patients was conducted from November 1, 2012 to May 31, 2013 in 4 chest clinics in Cameroon. The adherence to asthma treatment was rated using Morisky Medication Adherence Scale. A multivariate logistic regression analysis was performed for the identification of factors associated with adherence to asthma treatment.
  
  
  RESULTS
  Among the 201 asthma patients included, 133 (66.2%) were female. The mean age of participants was 41.2 years. Sixty-one (30.3%) of the patients did not visit the chest physician during the last year prior to the study. Asthma was well controlled in 118 patients (58.7%). The prevalence of low adherence rate to asthma controller therapy was 44.8% and the absence of any chest specialist visit within the last 12 months was the only factor associated with the low adherence rate to asthma treatment (OR 5.57 ; 95% CI 2.84-10.93).
  
  
  CONCLUSIONS
  The adherence rate to asthma controller therapy in Cameroon is low and it could be improved if scheduled visits are respected by patients.
authors.affiliation: Department of Internal Medicine, Douala General Hospital, Douala, Cameroon; Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon.
authors.forename: Bertrand Hugo Mbatchou
authors.initials: BH
authors.lastname: Ngahane
authors.affiliation: Yaounde Jamot Hospital, Pneumology service, Yaounde, Cameroon; Faculty of Medicine and Biomedical Sciences, Internal medicine and specialities, University of Yaounde I, Yaounde, Cameroon.
authors.forename: Eric Walter
authors.initials: EW
authors.lastname: Pefura-Yone
authors.affiliation: Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon.
authors.forename: Maïmouna
authors.initials: M
authors.lastname: Mama
authors.affiliation: Centre des Maladies Respiratoires, Douala, Cameroon.
authors.forename: Bruno
authors.initials: B
authors.lastname: Tengang
authors.affiliation: Faculty of Medicine and Pharmaceutical Sciences, University of Douala, Cameroon.
authors.forename: Motto Malea
authors.initials: MM
authors.lastname: Nganda
authors.affiliation: Douala Laquintinie Hospital, Cameroon.
authors.forename: Adeline
authors.initials: A
authors.lastname: Wandji
authors.affiliation: Yaounde Jamot Hospital, Pneumology service, Yaounde, Cameroon.
authors.forename: Ubald
authors.initials: U
authors.lastname: Olinga
authors.affiliation: Cabinet de Pneumologie d'Akwa, Cameroon.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Nyankiyé
authors.affiliation: Faculty of Medicine and Biomedical Sciences, Internal medicine and specialities, University of Yaounde I, Yaounde, Cameroon.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Afane Ze
authors.affiliation: Faculty of Health Sciences, University of Bamenda, Cameroon.
authors.forename: Christopher
authors.initials: C
authors.lastname: Kuaban
mesh_terms: D000280:Administration, Inhalation; D000293:Adolescent; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage* / Q000627:therapeutic use; D000318:Adrenergic beta-Agonists / Q000008:administration & dosage* / Q000627:therapeutic use; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000188:drug therapy*; D002163:Cameroon / Q000453:epidemiology; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D015438:Health Behavior; D006801:Humans; D008297:Male; D008511:Medicine; D008875:Middle Aged; D009819:Office Visits / Q000706:statistics & numerical data; D012737:Sex Factors; D012959:Socioeconomic Factors; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D000305:Adrenal Cortex Hormones; D000318:Adrenergic beta-Agonists
keywords: Africa; Allergy; medication adherence