title: Antioxidant Activity of Marine Algal Polyphenolic Compounds: A Mechanistic Approach.
abstract: Polyphenolic compounds isolated from marine algae exhibit a broad spectrum of beneficial biological properties, including antioxidant, anticancer, antimicrobial, anti-inflammatory, and antidiabetic activities, along with several other bioactivities centered on their antioxidant properties. Consequently, polyphenolic compounds are increasingly being investigated for their potential use in food, cosmetic, and pharmaceutical applications. The antioxidant activities of these compounds have been explored widely through experimental studies. Nonetheless, a theoretical understanding of the structural and electronic properties could broaden research perspectives, leading to the identification and synthesis of efficient structural analogs with prophylactic uses. This review briefly summarizes the current state of knowledge regarding antioxidant polyphenolic compounds in marine algae with an attempt to describe the structure-activity relationship.
authors.affiliation: 1 Department of Marine Life Science, Jeju National University , Jeju, Republic of Korea.
authors.forename: I P Shanura
authors.initials: IP
authors.lastname: Fernando
authors.affiliation: 2 Department of Food Science and Nutrition, Dankook University , Gyeonggi, Republic of Korea.
authors.forename: Misook
authors.initials: M
authors.lastname: Kim
authors.affiliation: 3 Food Safety and Processing Research Division, National Institute of Fisheries Science , Busan, Republic of Korea.
authors.forename: Kwang-Tae
authors.initials: KT
authors.lastname: Son
authors.affiliation: 2 Department of Food Science and Nutrition, Dankook University , Gyeonggi, Republic of Korea.
authors.forename: Yoonhwa
authors.initials: Y
authors.lastname: Jeong
authors.affiliation: 1 Department of Marine Life Science, Jeju National University , Jeju, Republic of Korea.
authors.forename: You-Jin
authors.initials: YJ
authors.lastname: Jeon
mesh_terms: D000975:Antioxidants; D003358:Cosmetics; D005419:Flavonoids; D005524:Food Technology; D006219:Halogens; D006293:Health Promotion; D015394:Molecular Structure; D059808:Polyphenols / Q000737:chemistry / Q000494:pharmacology*; D017382:Reactive Oxygen Species; D012624:Seaweed / Q000737:chemistry*; D013329:Structure-Activity Relationship; D013634:Tannins; D013678:Technology, Pharmaceutical
chemical_list: D000975:Antioxidants; D003358:Cosmetics; D005419:Flavonoids; D006219:Halogens; D059808:Polyphenols; D017382:Reactive Oxygen Species; D013634:Tannins
keywords: ROS; flavonoids; halogenated phenolic compounds; phenolic acids; phlorotannins; radical scavenging mechanism; seaweed