title: Presurgical language mapping in epilepsy: Using fMRI of reading to identify functional reorganization in a patient with long-standing temporal lobe epilepsy.
abstract: We report a 55-year-old, right-handed patient with intractable left temporal lobe epilepsy, who previously had a partial left temporal lobectomy. The patient could talk during seizures, suggesting that he might have language dominance in the right hemisphere. Presurgical fMRI localization of language processing including reading of exception and regular words, pseudohomophones, and dual meaning words confirmed the clinical hypothesis of right language dominance, with only small amounts of activation near the planned surgical resection and, thus, minimal eloquent cortex to avoid during surgery. Postoperatively, the patient was rendered seizure-free without speech deficits.
authors.affiliation: Department of Psychology, 9 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5A5, Canada.
authors.forename: Layla
authors.initials: L
authors.lastname: Gould
authors.affiliation: Department of Psychology, 9 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5A5, Canada; Department of Medical Imaging, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK S7N 0W8, Canada.
authors.forename: Marla J S
authors.initials: MJ
authors.lastname: Mickleborough
authors.affiliation: Department of Surgery, Division of Neurosurgery, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK S7N OW8, Canada.
authors.forename: Adam
authors.initials: A
authors.lastname: Wu
authors.affiliation: Department of Neurology, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK S7N OW8, Canada.
authors.forename: Jose
authors.initials: J
authors.lastname: Tellez
authors.affiliation: Department of Psychology, 9 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5A5, Canada.
authors.forename: Chelsea
authors.initials: C
authors.lastname: Ekstrand
authors.affiliation: Department of Psychology, 9 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5A5, Canada.
authors.forename: Eric
authors.initials: E
authors.lastname: Lorentz
authors.affiliation: Department of Medical Imaging, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK S7N 0W8, Canada.
authors.forename: Tasha
authors.initials: T
authors.lastname: Ellchuk
authors.affiliation: Department of Medical Imaging, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK S7N 0W8, Canada.
authors.forename: Paul
authors.initials: P
authors.lastname: Babyn
authors.affiliation: Department of Psychology, 9 Campus Drive, University of Saskatchewan, Saskatoon, SK S7N 5A5, Canada; Department of Surgery, Division of Neurosurgery, Royal University Hospital, 103 Hospital Drive, Saskatoon, SK S7N OW8, Canada.
authors.forename: Ron
authors.initials: R
authors.lastname: Borowsky
keywords: Language; Neurosurgery; Reading; Temporal lobe epilepsy; fMRI