title: Imaging Bioorthogonal Groups in Their Ultrastructural Context with Electron Microscopy.
abstract: Spitting image: Herein a recent paper on the imaging of bioorthogonal groups using three-dimensional electron microscopy is discussed. The work has demonstrated electron microscopy imaging as a technique suitable for gaining structural information on bioorthogonal groups in their cellular context.
authors.affiliation: Leiden Institute of Chemistry/Institute of Chemical Immunology, Bioorganic Synthesis, Leiden University, Einsteinweg 55, 2333, CC, Leiden, The Netherlands.
authors.forename: Daphne M
authors.initials: DM
authors.lastname: van Elsland
authors.affiliation: Leiden Institute of Chemistry/Institute of Chemical Immunology, Bioorganic Synthesis, Leiden University, Einsteinweg 55, 2333, CC, Leiden, The Netherlands. s.i.van.kasteren@chem.leidenuniv.nl.
authors.forename: Sander I
authors.identifier: 0000-0003-3733-818X
authors.initials: SI
authors.lastname: van Kasteren
keywords: electron microscopy; fluorescence; imaging; photochemistry; singlet oxygen