title: External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges.
authors.affiliation: Research Institute for Primary Care and Health Sciences, Keele University, Keele ST5 5BG, Staffordshire, UK r.riley@keele.ac.uk.
authors.forename: Richard D
authors.initials: RD
authors.lastname: Riley
authors.affiliation: Research Institute for Primary Care and Health Sciences, Keele University, Keele ST5 5BG, Staffordshire, UK.
authors.forename: Joie
authors.initials: J
authors.lastname: Ensor
authors.affiliation: Institute of Applied Health Research, University of Birmingham, Edgbaston, Birmingham, UK.
authors.forename: Kym I E
authors.initials: KI
authors.lastname: Snell
authors.affiliation: Julius Centre for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands Cochrane Netherlands, University Medical Center Utrecht, Utrecht, Netherlands.
authors.forename: Thomas P A
authors.initials: TP
authors.lastname: Debray
authors.affiliation: Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
authors.forename: Doug G
authors.initials: DG
authors.lastname: Altman
authors.affiliation: Julius Centre for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, Netherlands Cochrane Netherlands, University Medical Center Utrecht, Utrecht, Netherlands.
authors.forename: Karel G M
authors.initials: KG
authors.lastname: Moons
authors.affiliation: Centre for Statistics in Medicine, Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, UK.
authors.forename: Gary S
authors.initials: GS
authors.lastname: Collins
mesh_terms: D066264:Datasets as Topic; D003661:Decision Support Techniques; D057286:Electronic Health Records; D006801:Humans; D015201:Meta-Analysis as Topic; D015233:Models, Statistical; D012042:Registries; D018570:Risk Assessment / Q000379:methods; D054928:Validation Studies as Topic