title: [Risks factors associated with intra-partum foetal mortality in pre-term infants].
abstract: BACKGROUND
  Pre-term delivery is one of the leading causes of foetal and perinatal mortality. However, perinatal risk factors associated with intra-partum foetal death in preterm deliveries have not been well studied.
  
  
  OBJECTIVE
  To analyse foetal mortality and perinatal risk factors associated with intra-partum foetal mortality in pregnancies of less than 32 weeks gestational age.
  
  
  METHODS
  The study included all preterm deliveries between 22 and 31 +1 weeks gestational age (WGA), born in a tertiary-referral hospital, over a period of 7 years (2008-2014). A logistic regression model was used to identify perinatal risk factors associated with intra-partum foetal mortality (foetal malformations and chromosomal abnormalities were excluded).
  
  
  RESULTS
  During the study period, the overall foetal mortality was 63.1% (106/168) (≥22 weeks of gestation) occurred in pregnancies of less than 32 WGA. A total of 882 deliveries between 22 and 31+6 weeks of gestation were included for analysis. The rate of foetal mortality was 11.3% (100/882). The rate of intra-partum foetal death was 2.6% (23/882), with 78.2% (18/23) of these cases occurring in hospitalised pregnancies. It was found that Assisted Reproductive Techniques, abnormal foetal ultrasound, no administration of antenatal steroids, lower gestational age, and small for gestational age, were independent risk factors associated with intra-partum foetal mortality.
  
  
  CONCLUSIONS
  This study showed that there is a significant percentage intra-partum foetal mortality in infants between 22 and 31+6 WGA. The analysis of intrapartum mortality and risk factors associated with this mortality is of clinical and epidemiological interest to optimise perinatal care and improve survival of preterm infants.
authors.affiliation: Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España. Electronic address: szeballitos@hotmail.com.
authors.forename: Susana
authors.initials: S
authors.lastname: Zeballos Sarrato
authors.affiliation: Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: Sonia
authors.initials: S
authors.lastname: Villar Castro
authors.affiliation: Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: Cristina
authors.initials: C
authors.lastname: Ramos Navarro
authors.affiliation: Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: Gonzalo
authors.initials: G
authors.lastname: Zeballos Sarrato
authors.affiliation: Servicio de Neonatología, Hospital General Universitario Gregorio Marañón, Madrid, España.
authors.forename: Manuel
authors.initials: M
authors.lastname: Sánchez Luna
mesh_terms: D005260:Female; D046689:Fetal Mortality; D005865:Gestational Age; D006801:Humans; D007231:Infant, Newborn; D007234:Infant, Premature; D007743:Labor, Obstetric; D008297:Male; D011247:Pregnancy; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Extreme prematurity; Factores de riesgo; Foetal mortality; Mortalidad fetal; Prematuridad; Risk factors