title: Using steric bulk for selective recognition; blocking the binding site to differentiate guests.
abstract: Selectivity is demonstrated in a supramolecular host:guest system using a receptor with a non-linear binding site. For the "open" receptor 1 strong binding for both flexible and rigid guests was observed. Receptor 2, with a "blocked" binding site, also bound flexible guests effectively but its affinity for rigid guests was 50 fold lower.
authors.affiliation: Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria 3216, Australia. fred.pfeffer@deakin.edu.au.
authors.forename: Ryan N
authors.initials: RN
authors.lastname: Robson
authors.affiliation: Centre for Chemistry and Biotechnology, School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria 3216, Australia. fred.pfeffer@deakin.edu.au.
authors.forename: Frederick M
authors.initials: FM
authors.lastname: Pfeffer