title: Straight Vessel Pattern and Rapid Filling Time: Characteristic Findings on Contrast-Enhanced Sonography of Testicular Lymphoma.
abstract: Six patients with 7 lesions that were histologically confirmed as primary testicular lymphoma were preoperatively investigated with a standardized sonographic protocol including contrast-enhanced sonography. Duplex and contrast-enhanced sonography showed marked hypervascularization in all 7 lesions. On contrast-enhanced sonography, the filling time of lymphomatous lesions was significantly shorter than the filling time of a size-matched sample of 10 patients with seminomas (P < .0001). The sonographic hallmarks of testicular lymphoma in our case series were as follows: (1) sharply demarcated homogeneous hypoechoic testicular lesions with marked hypervascularization; (2) a rapid (<7 seconds) filling time of contrast bubbles; and (3) a straight and parallel course of intralesional vessels on contrast-enhanced sonography.
authors.affiliation: Department of Internal Medicine, Albertinen-Krankenhaus, Hamburg, Germany guntram.lock@albertinen.de.
authors.forename: Guntram
authors.initials: G
authors.lastname: Lock
authors.affiliation: Department of Internal Medicine, Albertinen-Krankenhaus, Hamburg, Germany.
authors.forename: Christa
authors.initials: C
authors.lastname: Schmidt
authors.affiliation: Department of Internal Medicine, Albertinen-Krankenhaus, Hamburg, Germany.
authors.forename: Claudia
authors.initials: C
authors.lastname: Schröder
authors.affiliation: Institute for Pathology, Albertinen-Krankenhaus, Hamburg, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Löning
authors.affiliation: Department of Urology, Albertinen-Krankenhaus, Hamburg, Germany.
authors.forename: Klaus-Peter
authors.initials: KP
authors.lastname: Dieckmann
mesh_terms: D000368:Aged; D003287:Contrast Media / Q000493:pharmacokinetics*; D003937:Diagnosis, Differential; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D010743:Phospholipids / Q000493:pharmacokinetics*; D013459:Sulfur Hexafluoride / Q000493:pharmacokinetics*; D013736:Testicular Neoplasms / Q000098:blood supply / Q000000981:diagnostic imaging*; D013737:Testis / Q000098:blood supply / Q000000981:diagnostic imaging; D013995:Time; D014463:Ultrasonography / Q000379:methods*
chemical_list: D003287:Contrast Media; D010743:Phospholipids; C420843:contrast agent BR1; D013459:Sulfur Hexafluoride
keywords: B-cell lymphoma; contrast-enhanced sonography; sonography; testicular lymphoma; testicular tumor