title: Gut microbiota and hematopoietic stem cell transplantation: where do we stand?
abstract: Advances in biological techniques have potentiated great progresses in understanding the interaction between human beings and the ∼10 to 100 trillion microbes living in their gastrointestinal tract: gut microbiota (GM). In this review, we describe recent emerging data on the role of GM in hematopoietic stem cell transplantation, with a focus on immunomodulatory properties in the immune system recovery and the impact in the development of the main complications, as GvHD and infections.
authors.affiliation: Pediatric Oncology and Haematology Unit 'Lalla Seràgnoli', Department of Pediatrics, University of Bologna, Sant'Orsola Malpighi Hospital, Bologna, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Zama
authors.affiliation: Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Biagi
authors.affiliation: Pediatric Oncology and Haematology Unit 'Lalla Seràgnoli', Department of Pediatrics, University of Bologna, Sant'Orsola Malpighi Hospital, Bologna, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Masetti
authors.affiliation: Pediatric Oncology and Haematology Unit 'Lalla Seràgnoli', Department of Pediatrics, University of Bologna, Sant'Orsola Malpighi Hospital, Bologna, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Gasperini
authors.affiliation: Pediatric Oncology and Haematology Unit 'Lalla Seràgnoli', Department of Pediatrics, University of Bologna, Sant'Orsola Malpighi Hospital, Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Prete
authors.affiliation: Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Candela
authors.affiliation: Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Brigidi
authors.affiliation: Pediatric Oncology and Haematology Unit 'Lalla Seràgnoli', Department of Pediatrics, University of Bologna, Sant'Orsola Malpighi Hospital, Bologna, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Pession
mesh_terms: D000069196:Gastrointestinal Microbiome / Q000276:immunology*; D006086:Graft vs Host Disease / Q000276:immunology / Q000382:microbiology; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D056747:Immunomodulation; D007239:Infections / Q000276:immunology / Q000382:microbiology