title: [PROGNOSTIC VALUE OF SOME HEMOSTASIS-RELATED, HOMOCYSTEINE, HIGH SENSITIVE C R P AND MULTIDETECTOR COMPUTED TOMOGRAPHY PARAMETERS IN PULMONARY EMBOLISM].
abstract: Nowadays, an arsenal of diagnostic methods is used in diagnosis of pulmonary embolism, which includes x-ray, angiography, perfusion-ventilation scintigraphy, CT and magnetic resonance imaging, Doppler and laboratory studies. Purpose of our study was to evaluate the diagnostic significance of determination of some parameters of hemostasis (D-dimer, Soluble fibrinmonomer complexes, fibrinogen), homocysteine, hs-CRP and multidetector computed tomography in suspected pulmonary embolism. We have examined 54 patients -31 men and 23 women, aged 18 to 76 years, with characteristics of pulmonary embolism. According to our data, Multidetector computed tomography angiopulmonography , measuring D-dimer, fibrinogen and related hyperhomocysteinemia with increased level of hs-CRP may serve as binding, diagnostically significant laboratory markers in the diagnosis and treatment efficacy of pulmonary thromboembolism.
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: F
authors.initials: F
authors.lastname: Todua
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: M
authors.initials: M
authors.lastname: Akhvlediani
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: E
authors.initials: E
authors.lastname: Vorobiova
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: A
authors.initials: A
authors.lastname: Baramidze
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: G
authors.initials: G
authors.lastname: Tsivtsivadze
authors.affiliation: Research Institute of Clinical Medicine, Tbilisi, Georgia.
authors.forename: D
authors.initials: D
authors.lastname: Gachechiladze
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D015415:Biomarkers / Q000097:blood; D002097:C-Reactive Protein / Q000032:analysis*; D016022:Case-Control Studies; D005260:Female; D005338:Fibrin Fibrinogen Degradation Products / Q000032:analysis; D005340:Fibrinogen / Q000032:analysis; D006487:Hemostasis; D006710:Homocysteine / Q000097:blood*; D006801:Humans; D008297:Male; D008875:Middle Aged; D061330:Multidetector Computed Tomography; D011379:Prognosis; D011655:Pulmonary Embolism / Q000097:blood / Q000175:diagnosis* / Q000000981:diagnostic imaging; D055815:Young Adult
chemical_list: D015415:Biomarkers; D005338:Fibrin Fibrinogen Degradation Products; C036309:fibrin fragment D; C011468:fibrinmonomer; D006710:Homocysteine; D005340:Fibrinogen; D002097:C-Reactive Protein