title: The Effects of Inhaled β-Adrenergic Agonists in Transient Tachypnea of the Newborn.
abstract: Aim. To investigate the efficacy of an inhaled β-adrenergic agonists in transient tachypnea of the newborn (TTN). Method. We retrospectively analyzed a cohort of 51 term infants (Group 1) and 37 term infants (Group 2) monitored in the newborn intensive care unit diagnosed with TTN. Infants in Group 1 received humidified oxygen alone, and infants in Group 2 were administered the inhaled β-2 agonist plus humidified oxygen. Results. TTN clinical respiratory assessment, respiratory rate, oxygen saturation values, need for supplemental oxygen therapy, blood gas PH, PO2, and duration of hospitalization were significantly improved in infants in Group 2 as compared with infants in Group 1 (P < .05). No statistically significant difference was observed with regard to blood glucose, potassium, heart rate, and PCO2 (P > .05). Conclusion. Inhaled β-adrenergic agonist added to humidified oxygen was found to improve clinical and laboratory parameters. We believe that further studies should be conducted with larger groups to demonstrate the efficacy of β-2 agonists in TTN patients.
authors.affiliation: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul.
authors.forename: Esengul
authors.initials: E
authors.lastname: Keleş
authors.affiliation: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul.
authors.forename: Arzu
authors.initials: A
authors.lastname: Gebeşçe
authors.affiliation: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Demirdöven
authors.affiliation: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul.
authors.forename: Hamza
authors.initials: H
authors.lastname: Yazgan
authors.affiliation: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul.
authors.forename: Bülent
authors.initials: B
authors.lastname: Baştürk
authors.affiliation: Department of Pediatrics, Fatih University, Istanbul Esengül Keleş, MD, Department of Pediatrics, Fatih University, Istanbul.
authors.forename: Alparslan
authors.initials: A
authors.lastname: Tonbul
keywords: allergy/immunology; critical care; general pediatrics; neonatology; pulmonology