title: The Prevalence of Diabetes Mellitus in COPD Patients with Severe and Very Severe Stage of the Disease.
abstract: OBJECTIVE
  The aim of the study was to investigate the prevalence of diabetes mellitus in privies diagnosed chronic obstructive pulmonary disease (COPD) patients with severe and very severe disease, which ware stable.
  
  
  METHODS
  We investigated 100 subjects, all of them smokers, with smoking status >10 years. They were stratified in two groups. It was clinical, randomized, cross sectional study. Besides demographic parameters, functional parameters, BMI, cholesterol, LDL and HDL, and the level of blood sugar was measured.
  
  
  RESULTS
  The prevalence of diabetes mellitus in our survey in total number of COPD patients with severe and very severe stage was 21%. In the very severe group were recorded significantly higher average values of glycaemia compared with severe group (7.67 ± 3.7 vs. 5.62 ± 0.9, p = 0.018). In the group with severe COPD, it was not confirmed any factor with significant predictive effect on the values of glycaemia. As independent significant factors that affect blood glucose in a group of very severe COPD were confirmed cholesterol (p <0.0001) and HDL (p = 0.018).
  
  
  CONCLUSIONS
  These results suggest that the presence of the COPD in patients itself is a factor that results in the clinical presentation of diabetes mellitus Type 2.
authors.affiliation: University Clinic of Pulmollogy and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Jagoda
authors.initials: J
authors.lastname: Stojkovikj
authors.affiliation: Institute for Epidemiology and Biostatistics and Medical Informatics, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Beti
authors.initials: B
authors.lastname: Zafirova-Ivanovska
authors.affiliation: University Clinic of Pulmollogy and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Biserka
authors.initials: B
authors.lastname: Kaeva
authors.affiliation: University Clinic of Cardiology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Sasha
authors.initials: S
authors.lastname: Anastasova
authors.affiliation: University Clinic of Pulmollogy and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Irena
authors.initials: I
authors.lastname: Angelovska
authors.affiliation: University Clinic of Pulmollogy and Allergology, Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Smiljko
authors.initials: S
authors.lastname: Jovanovski
authors.affiliation: School of Doctoral Studies at Faculty of Medicine, Ss Cyril and Methodius University of Skopje, Skopje, Republic of Macedonia.
authors.forename: Dragana
authors.initials: D
authors.lastname: Stojkovikj
keywords: comorbidity; prevalence of diabetes mellitus type 2; severe COPD; very severe COPD