title: Chemical Adhesion of Polyalkenoate-based Adhesives to Hydroxyapatite.
abstract: OBJECTIVE
  To evaluate the chemical interaction between synthetic hydroxyapatite (HAp) and polyalkenoic acid copolymer- based (also known as Vitrebond copolymer [VCP]) adhesives.
  
  
  METHODS
  Six dentin adhesive formulations were used: 1) Adper Single Bond Plus (SB); 2) SB formulation without VCP (SBnoVCP); 3) Adper Easy Bond (EB); 4) EB formulation without VCP (EBnoVCP); 5) Scotchbond Universal adhesive (SBU); 6) SBU formulation without VCP (SBUnoVCP). Each adhesive was mixed with HAp, polymerized, and analyzed using FTIR and 13C/31P NMR spectroscopy.
  
  
  RESULTS
  The FTIR spectra of SB+HAp indicated that the carbonyl group changed absorption wavenumber compared to that of SBnoVCP+HAp. 13C NMR analysis showed that the presence of methacrylated phosphoric esters in the EB and SBU formulations led to similar carbonyl resonance with or without VCP. 31P NMR revealed a resonance shift at 0.5 ppm for SB+HAp, EB+HAp and SBU+HAp spectra. In comparison with EB+HAp and SBU+HAp, a slight fade-out of the same resonance shift for EBnoVCP+HAp and SBUnoVCP+HAp was observed without completely disappearing, respectively, meaning that VCP might induce a modification of phosphorus moieties in addition to the ionic interaction between phosphate ester groups and HAp.
  
  
  CONCLUSIONS
  Our data suggests that a chemical interaction occurred between VCP-containing adhesives and synthetic HAp.
authors.forename: Ana
authors.initials: A
authors.lastname: Sezinando
authors.forename: María Linares
authors.initials: ML
authors.lastname: Serrano
authors.forename: Victoria Morales
authors.initials: VM
authors.lastname: Pérez
authors.forename: Rafael A García
authors.initials: RA
authors.lastname: Muñoz
authors.forename: Laura
authors.initials: L
authors.lastname: Ceballos
authors.forename: Jorge
authors.initials: J
authors.lastname: Perdigão
mesh_terms: D065966:Absorption, Physicochemical; D000268:Adhesiveness; D000447:Aldehydes / Q000737:chemistry; D017438:Bisphenol A-Glycidyl Methacrylate / Q000737:chemistry; D002247:Carbon Isotopes; D003188:Composite Resins / Q000737:chemistry; D001840:Dental Bonding; D017886:Durapatite / Q000737:chemistry*; D005899:Glass Ionomer Cements / Q000737:chemistry*; D006801:Humans; D006860:Hydrogen Bonding; D009682:Magnetic Resonance Spectroscopy; D008422:Materials Testing; D008689:Methacrylates / Q000737:chemistry; D010758:Phosphorus / Q000737:chemistry; D010759:Phosphorus Isotopes; D058105:Polymerization; D019279:Resin Cements / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000447:Aldehydes; D002247:Carbon Isotopes; D003188:Composite Resins; D005899:Glass Ionomer Cements; D008689:Methacrylates; D010759:Phosphorus Isotopes; D019279:Resin Cements; C511238:Single Bond Plus; C584661:easy bond; C067790:Vitrabond; D010758:Phosphorus; D017438:Bisphenol A-Glycidyl Methacrylate; C041330:Scotchbond; D017886:Durapatite