title: Mycoplasma genitalium in Toronto, Ont:   Estimates of prevalence and macrolide resistance.
abstract: OBJECTIVE
  To estimate the prevalence of Mycoplasma genitalium in Toronto, Ont; detect mutations associated with macrolide and fluoroquinolone resistance; and describe treatment outcomes.
  
  
  METHODS
  Prospective, cross-sectional study.
  
  
  METHODS
  A sexual health clinic in Toronto.
  
  
  METHODS
  A consecutive sample of men and women attending the sexual health clinic between September 1, 2013, and December 20, 2013.
  
  
  METHODS
  Participants underwent testing for M genitalium, along with standard sexually transmitted infection screening. All samples that had positive results for M genitalium were tested for mutations associated with resistance to macrolides and fluoroquinolones. Mycoplasma genitalium treatment was based on resistance profile and verified with a test of cure.
  
  
  METHODS
  Positive results for M genitalium and antibiotic resistance.
authors.forename: Dionne
authors.initials: D
authors.lastname: Gesink
authors.forename: C Sarai
authors.initials: CS
authors.lastname: Racey
authors.forename: Christine
authors.initials: C
authors.lastname: Seah
authors.forename: Sandra
authors.initials: S
authors.lastname: Zittermann
authors.forename: Leo
authors.initials: L
authors.lastname: Mitterni
authors.forename: Jerry
authors.initials: J
authors.lastname: Juzkiw
authors.forename: Heather
authors.initials: H
authors.lastname: Jamieson
authors.forename: Jane
authors.initials: J
authors.lastname: Greer
authors.forename: Sudesh
authors.initials: S
authors.lastname: Singh
authors.forename: Jørgen Skov
authors.initials: JS
authors.lastname: Jensen
authors.forename: Vanessa
authors.initials: V
authors.lastname: Allen
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000008:administration & dosage*; D017963:Azithromycin / Q000008:administration & dosage; D003430:Cross-Sectional Studies; D004318:Doxycycline / Q000008:administration & dosage; D024881:Drug Resistance, Bacterial / Q000235:genetics*; D005260:Female; D024841:Fluoroquinolones / Q000008:administration & dosage / Q000009:adverse effects; D006801:Humans; D018942:Macrolides / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D000077266:Moxifloxacin; D009175:Mycoplasma Infections / Q000188:drug therapy* / Q000453:epidemiology*; D045704:Mycoplasma genitalium / Q000187:drug effects / Q000235:genetics; D009864:Ontario / Q000453:epidemiology; D011446:Prospective Studies; D012737:Sex Factors; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D024841:Fluoroquinolones; D018942:Macrolides; D017963:Azithromycin; D004318:Doxycycline; D000077266:Moxifloxacin