title: Factors Influencing the Management of Unruptured Intracranial Aneurysms.
abstract: Background Deciding how to manage an unruptured intracranial aneurysm can be difficult for patients and physicians due to controversies about management. The decision as to when and how to intervene may be variable depending on physicians' interpretation of available data regarding natural history and morbidity and mortality of interventions. Another significant factor in the decision process is the patients' conception of the risks of rupture and interventions and the psychological burden of harboring an unruptured intracranial aneurysm. Objective  To describe which factors are being considered when patients and their physicians decide how to manage unruptured intracranial aneurysms.  Materials & methods  In a retrospective chart review study, we identified patients seen for evaluation of an unruptured intracranial aneurysm. Data was collected regarding patient and aneurysm characteristics. The physician note pertaining to the management decision was reviewed for documented reasons for intervention. Results  Of 88 patients included, 36 (41%) decided to undergo open or endovascular surgery for at least one unruptured intracranial aneurysm. Multiple aneurysms were present in 14 (16%) patients. Younger patients and current smokers were more likely to undergo surgery, but gender and race did not affect management. Aneurysm size and location strongly influenced management. The most common documented reasons underlying the decision of whether to intervene were the risk of rupture, aneurysm size, and risks of the procedure. For 23 aneurysms (21%), there were no factors documented for the management decision.  Conclusion  The risk of rupture of unruptured intracranial aneurysms may be underestimated by currently available natural history data. Major factors weighed by physicians in management decisions include aneurysm size and location, the patient's age, and medical comorbidities along with the risk of procedural complications. Additional data is needed to define specific aneurysm characteristics and patient factors that influence rupture, in particular in small aneurysms. Physicians should carefully document their rationale along with the patient's perspective given the controversial nature of these management decisions.
authors.affiliation: Neurology, Massachusetts General Hospital.
authors.forename: Rebecca L
authors.initials: RL
authors.lastname: Gillani
authors.affiliation: Internal Medicine, UC Irvine Medical Center.
authors.forename: Katherine M
authors.initials: KM
authors.lastname: Podraza
authors.affiliation: Neurology, UC Davis Health System.
authors.forename: Nijee
authors.initials: N
authors.lastname: Luthra
authors.affiliation: Neurosurgery, Kalispell Regional Healthcare.
authors.forename: Thomas C
authors.initials: TC
authors.lastname: Origitano
authors.affiliation: Neurology, Neurosurgery, Loyola University Chicago, Stritch School of Medicine, Maywood, Illinois.
authors.forename: Michael J
authors.initials: MJ
authors.lastname: Schneck
keywords: cerebral aneurysm; decision making; subarachnoid hemorrhage; unruptured intracranial aneurysm