title: N-Heterocyclic Carbene/Lewis Acid Catalyzed Enantioselective Aerobic Annulation of α,β-Unsaturated Aldehydes with 1,3-Dicarbonyl Compounds.
abstract: A novel and efficient aerobic asymmetric cyclization reaction of cinnamaldehydes and 1,3-dicarbonyl compounds through oxidative NHC-catalysis has been developed, and it allows the synthesis of a wide range of enantiomeric enriched dihydropyranone derivatives in good yields with good to excellent enantioselectivities. Various α,β-unsaturated aldehydes with aliphatic and aromatic substitution groups and 1,3-dicarbonyl compounds were well tolerated. The air was directly used as the oxidant, which made this asymmetric cyclization reaction in a highly efficient, cheap, and green manner.
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Danbo
authors.initials: D
authors.lastname: Xie
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Shen
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Qiliang
authors.initials: Q
authors.lastname: Chen
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Jiaqi
authors.initials: J
authors.lastname: Zhou
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Zeng
authors.affiliation: College of Materials, Chemistry and Chemical Engineering, Hangzhou Normal University , Hangzhou 310036, China.
authors.forename: Guofu
authors.initials: G
authors.lastname: Zhong