title: Editorial: Magnetic Resonance Elastography and Non-Alcoholic Fatty Liver Disease: Time for an Upgrade?
abstract: Elastography techniques, such as two-dimensional magnetic resonance elastography (2D-MRE) are increasingly used for the non-invasive assessment of liver fibrosis in patients with nonalchoholic fatty liver disease (NAFLD). Loomba et al. demonstrate that 3D-MRE (shear wave frequency 40 Hz) had even greater diagnostic accuracy than the commercially available 2D-MRE (shear wave frequency 60 Hz) in diagnosing advanced fibrosis (area under the receiver operator curve, AUROC 0.981 vs. 0.921, P<0. 05) using liver biopsy as reference standard. Despite limitations, MRE serves as an important tool in risk stratification for patients with NAFLD.
authors.affiliation: Washington University, St. Louis, Missouri, USA.
authors.forename: Avegail
authors.initials: A
authors.lastname: Flores
authors.affiliation: Baylor University Medical Center, Dallas, Texas, USA.
authors.forename: Sumeet K
authors.initials: SK
authors.lastname: Asrani
mesh_terms: D057186:Comparative Effectiveness Research; D061827:Dimensional Measurement Accuracy; D054459:Elasticity Imaging Techniques / Q000379:methods*; D006801:Humans; D021621:Imaging, Three-Dimensional / Q000379:methods*; D008099:Liver / Q000000981:diagnostic imaging*; D008103:Liver Cirrhosis / Q000175:diagnosis / Q000209:etiology; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications / Q000175:diagnosis; D015203:Reproducibility of Results