title: Laterality of radiographic osteoarthritis of the knee.
abstract: There are few reports of the laterality in radiological knee osteoarthritis (ROA). This study aimed to evaluate laterality in terms of the minimum joint space width (mJSW) and osteophyte areas (OFs) in a cross-sectorial general population screen and elucidate the association between laterality and risk of osteoarthritis. We enrolled 330 participants (mean age 64.6 years) and examined the presence of ROA (Kellgren-Lawrence grade ≧ 2) laterality in terms of the mJSW and OF on the medial tibia using auto-measuring software. Moreover, we examined the association between laterality and leg dominance. The right and left medial mJSWs were 4.02 ± 0.98 mm and 4.05 ± 1.01 mm, respectively, showing no laterality; the laterals were also similar. The participants who had osteophytes ≥1 mm2in the right, left, and bilateral knees were 15, 37, and 57 respectively, with osteophytes being significantly more common in the left knee. The OF was significantly larger in the left knee. Conversely, the medial and lateral mJSWs and OF did not differ according to leg dominance. The prevalence of ROA was higher and the OF was more pronounced in the left knee. However, the mJSW showed no laterality. Additionally, the mJSW and OF showed no differences according to leg dominance.
authors.affiliation: a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Daigo
authors.initials: D
authors.lastname: Komatsu
authors.affiliation: a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Kazuma
authors.initials: K
authors.lastname: Ikeuchi
authors.affiliation: a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Toshihisa
authors.initials: T
authors.lastname: Kojima
authors.affiliation: a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Takegami
authors.affiliation: a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Takafumi
authors.initials: T
authors.lastname: Amano
authors.affiliation: b Yoshida Orthopedic Hospital , Aichi , Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Tsuboi
authors.affiliation: a Department of Orthopaedic Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Ishiguro
authors.affiliation: c Department of Hip and Knee Reconstructive Surgery , Nagoya University Graduate School of Medicine , Aichi , Japan.
authors.forename: Yukiharu
authors.initials: Y
authors.lastname: Hasegawa
mesh_terms: D000368:Aged; D015331:Cohort Studies; D003430:Cross-Sectional Studies; D005080:Exercise Test; D005260:Female; D007839:Functional Laterality; D006801:Humans; D007564:Japan; D007717:Knee / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000000981:diagnostic imaging* / Q000453:epidemiology / Q000503:physiopathology*; D012720:Severity of Illness Index
keywords: Osteoarthritis; epidemiology; knee; laterality; plain radiograph