title: Vesicular Hand Dermatitis in a Child: Allergy to Methylisothiazolinone.
abstract: A 7-year-old girl presented with a history of vesicular hand dermatitis that only partially improved with the use of steroids. Patch testing revealed a 1+ reaction to 0.2% aqueous methylisothiazolinone (MI) and 0.01% aqueous methylchloroisothazolinone/methylisothiazolinone (MCI/MI). Dyshidrosiform hand dermatitis is rare in children younger than 10 years of age, and this pattern has not been reported with MCI/MI allergy.
authors.affiliation: Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin. skhanna4@wisc.edu.
authors.forename: Saira
authors.initials: S
authors.lastname: Khanna
authors.affiliation: Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.
authors.forename: Margo
authors.initials: M
authors.lastname: Reeder
mesh_terms: D002648:Child; D017449:Dermatitis, Allergic Contact / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D004202:Disinfectants / Q000009:adverse effects*; D005260:Female; D006229:Hand Dermatoses / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology; D006801:Humans; D010328:Patch Tests; D013844:Thiazoles / Q000009:adverse effects*
chemical_list: D004202:Disinfectants; D013844:Thiazoles; C011506:2-methyl-4-isothiazolin-3-one