title: [Correlation between Plasma microRNA Expression and Acute Graft-Versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation].
abstract: OBJECTIVE
  To investigate the microRNA (miRNA) expression in plasma of patients with aGVHD and without aGVHD after allo-hematopoietic stem cell transplantation (allo-HSCT).
  
  
  METHODS
  The miRNAs (miR-423, mirR199a-3p, miR93*, miR377) expression levels in peripheral blood plasma of 25 patients before and after allo-HSCT were detected by real-time PCR.
  
  
  RESULTS
  miR-423, miR199a-3p and miR-93* in aGVHD group were significantly upregulated (P<0.05); miR-377 expression was not significantly different between aGVHD and non-aGVHD (P>0.05).
  
  
  CONCLUSIONS
  The expression of miR-423, miR-199a-3p, miR-93* are upregulated in aGVHD group, which can be used as biomarkes to monitor and to diagnose aGVHD.
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Bin
authors.initials: B
authors.lastname: Hu
authors.affiliation: Department of Hematology, Forty-fourth Hospital of Chinese PLA, Guiyang 550009, Guizhou Province, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Fu
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Si-Yong
authors.initials: SY
authors.lastname: Huang
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Xiao-Tong
authors.initials: XT
authors.lastname: Gao
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Dan-Hui
authors.initials: DH
authors.lastname: Li
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Xue-Qian
authors.initials: XQ
authors.lastname: Yan
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Yang-Ping
authors.initials: YP
authors.lastname: Zhang
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China.
authors.forename: Li
authors.initials: L
authors.lastname: Liu
authors.affiliation: Department of Hematology, Tangdu Hosipital, Fourth Military Medical Uiniversity, Xi'an 710038, Shaanxi Province, China. E-mail: liangym@fmmu.edu.cn.
authors.forename: Ying-Min
authors.initials: YM
authors.lastname: Liang
mesh_terms: D015415:Biomarkers / Q000097:blood; D006086:Graft vs Host Disease / Q000097:blood / Q000473:pathology*; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D035683:MicroRNAs / Q000097:blood*; D060888:Real-Time Polymerase Chain Reaction; D015854:Up-Regulation
chemical_list: D015415:Biomarkers; D035683:MicroRNAs