title: Neonatal kaposiform hemangioendothelioma of the spleen associated with Kasabach-Merritt phenomenon.
abstract: Kaposiform hemangioendothelioma is a rare locally aggressive vascular tumor that usually manifests during early childhood. Typically the lesion presents with skin, soft tissue and bone involvement and is characterized histologically by ill-defined nodularity and the presence of spindle cells with resemblance to Kaposi's sarcoma. We report a rare neonatal case of a splenic kaposiform hemangioendothelioma associated with Kasabach-Merritt phenomenon that was diagnosed with radiographic imaging. Because of the rapid onset of thrombocytopenia and anemia, the patient required urgent splenectomy with subsequent resolution of the blood dyscrasias.
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Samuel A
authors.initials: SA
authors.lastname: Shabtaie
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Mark
authors.initials: M
authors.lastname: Owyong
authors.affiliation: Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Catalina
authors.initials: C
authors.lastname: Ruiz-Mesa
authors.affiliation: Division of Pediatric Hematology-Oncology, Department of Pediatrics, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Fernando F
authors.initials: FF
authors.lastname: Corrales-Medina
authors.affiliation: Department of Pathology, Holtz Children's Hospital, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Claudia P
authors.initials: CP
authors.lastname: Rojas
authors.affiliation: Department of Pediatric Radiology, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Juan C
authors.initials: JC
authors.lastname: Infante
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Holly L
authors.initials: HL
authors.lastname: Neville
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Eduardo A
authors.initials: EA
authors.lastname: Perez
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL.
authors.forename: Juan E
authors.initials: JE
authors.lastname: Sola
authors.affiliation: Division of Pediatric Surgery, DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, FL. Electronic address: ahogan@med.miami.edu.
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Hogan
mesh_terms: D003937:Diagnosis, Differential; D006390:Hemangioendothelioma / Q000175:diagnosis* / Q000601:surgery; D006801:Humans; D007231:Infant, Newborn; D059885:Kasabach-Merritt Syndrome / Q000175:diagnosis* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D011859:Radiography; D012514:Sarcoma, Kaposi / Q000175:diagnosis* / Q000601:surgery; D013154:Spleen / Q000000981:diagnostic imaging*; D013156:Splenectomy; D013160:Splenic Neoplasms / Q000175:diagnosis* / Q000601:surgery
keywords: Kaposiform hemangioendothelioma; Kasabach-Merritt phenomenon; Neonatal kaposiform hemangioendothelioma; Splenic mass; Vascular tumor