title: [Acupuncture combined with western medication for mild cognitive disorder after stroke: a rando- mized controlled trial].
abstract: OBJECTIVE
  To verify the clinical effect of the penetration acupuncture at the acupoints of governor vessel(GV) and bladder meridian on head for mild cognitive disorder after stroke.
  
  
  METHODS
  One hundred and ten patients were randomly divided into an observation group and a control group, 55 cases in each one. Penetration acupuncture was used at the acupoints of GV and bladder meridian on head in the observation group,namely Wuchu (BL 5) to Chengguang (BL 6) and Tongtian (BL 7) to Luoque (BL 8) bilaterally, and Shenting (GV 24) to Xinhui (GV 22), Qianding (GV 21) to Baihui (GV 20), Houding (GV 19) to Qiangjian (GV 18). Body acupuncture and conventional western medication were applied in the both two groups. Acupuncture was adopted once a day, five times a week and eight weeks totally. The changes of Montreal Cognitive Assessment (MoCA), Mini mental state examination scale(MMSE), self-rating depressive scale (SDS) and activities of daily living scale (Barthel index) were compared between the two groups before treatment, in the middle of treatment(at the forth week) after treatment(at the eighth week) and in three weeks after treatment(follow-up).
  
  
  RESULTS
  After treatment of four and eight weeks and at the time of follow-up, the results of MoCA, MMSE, SDS and Barthel index were apparently im proved compared with those before treatment in the two groups (all P < 0.01). After treatment of eight weeks and at the time of follow-up, the scores of MoCA and SDS were obviously improved in the observation group compared with those in the control group (P < 0.01, P < 0.05). The improvements of MMSE in the observation group were more marked than those in the control group at all times (P < 0.01, P < 0.05). But there was no statistical significance about the change of Barthel index between the two groups (all P > 0.05).
  
  
  CONCLUSIONS
  Penetration acupuncture at the acupoints of GV and bladder meridian on head can remarkablely improve the cognitive function of the patients with mild cognitive disorder after stroke,and have some efficacy of relieving the bad mood such as depression.
authors.forename: Xiaojun
authors.initials: X
authors.lastname: Chen
authors.forename: Jianqiao
authors.initials: J
authors.lastname: Fang
authors.forename: Yue
authors.initials: Y
authors.lastname: Shang
authors.forename: Ruijie
authors.initials: R
authors.lastname: Ma
authors.forename: Zhen
authors.initials: Z
authors.lastname: Fang
authors.forename: Lihua
authors.initials: L
authors.lastname: Xuan
authors.forename: Xiang
authors.initials: X
authors.lastname: Wu
authors.forename: Yehua
authors.initials: Y
authors.lastname: Bao
authors.forename: Shunxi
authors.initials: S
authors.lastname: Chen
mesh_terms: D000203:Activities of Daily Living; D015669:Acupuncture Points; D015670:Acupuncture Therapy; D000368:Aged; D000369:Aged, 80 and over; D003071:Cognition; D060825:Cognitive Dysfunction / Q000188:drug therapy / Q000209:etiology / Q000523:psychology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D008297:Male; D016740:Meridians; D008875:Middle Aged; D020521:Stroke / Q000150:complications*; D016896:Treatment Outcome