title: Rapid Microcystin Determination Using a Paper Spray Ionization Method with a Time-of-Flight Mass Spectrometry System.
abstract: The eutrophication of surface water sources and climate changes have resulted in an annual explosion of cyanobacterial blooms in many irrigating and drinking water resources. To decrease health risks to the public, a rapid real time method for the synchronous determination of two usually harmful microcystins (MC-RR and MC-LR) in environmental water samples was built by employing a paper spray ionization method coupled with a time-of-flight mass spectrometer system. With this approach, direct analysis of microcystin mixtures without sample preparation has been achieved. Rapid detection was performed, simulating the release process of microcystins in reservoir water samples, and the routine detection frequency was every three minutes. The identification time of microcystins was reduced from several hours to a few minutes. The limit of detection is 1 μg/L, and the limit of quantitation is 3 μg/L. This method displays the ability for carrying out rapid, direct, and high-throughput experiments for determination of microcystins, and it would be of significant interest for environmental and food safety applications.
authors.affiliation: Institute of Atmospheric Environment Safety and Pollution Control, Jinan University , Guangzhou 510632, China.|Department of Ecology, Jinan University , Guangzhou 510632, China.
authors.forename: Xiaoqiang
authors.initials: X
authors.lastname: Zhu
authors.affiliation: Institute of Atmospheric Environment Safety and Pollution Control, Jinan University , Guangzhou 510632, China.|Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution , Guangzhou 510632, China.
authors.forename: Zhengxu
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Institute of Atmospheric Environment Safety and Pollution Control, Jinan University , Guangzhou 510632, China.|Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution , Guangzhou 510632, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Gao
authors.affiliation: Institute of Atmospheric Environment Safety and Pollution Control, Jinan University , Guangzhou 510632, China.|Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution , Guangzhou 510632, China.
authors.forename: Xue
authors.initials: X
authors.lastname: Li
authors.affiliation: Institute of Atmospheric Environment Safety and Pollution Control, Jinan University , Guangzhou 510632, China.|Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution , Guangzhou 510632, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.affiliation: Guangzhou Hexin Analytical Instrument Co., Ltd. , Guangzhou 510530, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhu
authors.affiliation: Guangzhou Hexin Analytical Instrument Co., Ltd. , Guangzhou 510530, China.
authors.forename: Ting
authors.initials: T
authors.lastname: Mo
authors.affiliation: Guangzhou Hexin Analytical Instrument Co., Ltd. , Guangzhou 510530, China.
authors.forename: Bao
authors.initials: B
authors.lastname: Huang
authors.affiliation: Institute of Atmospheric Environment Safety and Pollution Control, Jinan University , Guangzhou 510632, China.|Guangdong Provincial Engineering Research Center for On-line Source Apportionment System of Air Pollution , Guangzhou 510632, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhou
mesh_terms: D005618:Fresh Water / Q000737:chemistry; D052998:Microcystins / Q000032:analysis*; D010209:Paper; D053719:Tandem Mass Spectrometry / Q000295:instrumentation / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000032:analysis*
chemical_list: D052998:Microcystins; D014874:Water Pollutants, Chemical; C078588:microcystin
keywords: microcystins; paper spray ionization; rapid determination; simultaneous analysis