title: Data from acellular human heart matrix.
abstract: Perfusion decellularization of cadaveric hearts removes cells and generates a cell-free extracellular matrix scaffold containing acellular vascular conduits, which are theoretically sufficient to perfuse and support tissue-engineered heart constructs. This article contains additional data of our experience decellularizing and testing structural integrity and composition of a large series of human hearts, "Acellular human heart matrix: a critical step toward whole heat grafts" (Sanchez et al., 2015) [1]. Here we provide the information about the heart decellularization technique, the valve competence evaluation of the decellularized scaffolds, the integrity evaluation of epicardial and myocardial coronary circulation, the pressure volume measurements, the primers used to assess cardiac muscle gene expression and, the characteristics of donors, donor hearts, scaffolds and perfusion decellularization process.
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Hospital Universitario de Salamanca, IBSAL, Salamanca, Spain.
authors.forename: Pedro L
authors.initials: PL
authors.lastname: Sánchez
authors.affiliation: Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Cell Production Unit, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: M Eugenia
authors.initials: ME
authors.lastname: Fernández-Santos
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: M Angeles
authors.initials: MA
authors.lastname: Espinosa
authors.affiliation: Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Cell Production Unit, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: M Angeles
authors.initials: MA
authors.lastname: González-Nicolas
authors.affiliation: Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Cell Production Unit, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Judith R
authors.initials: JR
authors.lastname: Acebes
authors.affiliation: Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Costanza
authors.affiliation: Department of Cardiovascular Development and Repair, Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Spain.
authors.forename: Isabel
authors.initials: I
authors.lastname: Moscoso
authors.affiliation: Department of Cardiac Surgery, Hospital General Universitario Gregorio Marañón. Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Hugo
authors.initials: H
authors.lastname: Rodríguez
authors.affiliation: Department of Pathology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid. Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Julio
authors.initials: J
authors.lastname: García
authors.affiliation: Photography & Comunication, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid. Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Jesús
authors.initials: J
authors.lastname: Romero
authors.affiliation: Center for Cardiovascular Repair, University of Minnesota, Minneapolis, USA.
authors.forename: Stefan M
authors.initials: SM
authors.lastname: Kren
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Bermejo
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Raquel
authors.initials: R
authors.lastname: Yotti
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Candelas Pérez
authors.initials: CP
authors.lastname: Del Villar
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Sanz-Ruiz
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Jaime
authors.initials: J
authors.lastname: Elizaga
authors.affiliation: Regenerative Medicine Research, Texas Heart Institute, Houston, USA.
authors.forename: Doris A
authors.initials: DA
authors.lastname: Taylor
authors.affiliation: Department of Cardiology, Hospital General Universitario Gregorio Marañón, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain; Bioartifical Organs Laboratory, Instituto de Investigación Sanitaria Gregorio Marañon (IiSGM), Madrid, Spain.
authors.forename: Francisco
authors.initials: F
authors.lastname: Fernández-Avilés