title: Relationship between metabolic syndrome and metabolic syndrome score and beta cell function by gender in Korean populations with obesity.
abstract: The present study was conducted to assess the relationships between metabolic syndrome and metabolic syndrome score (MSS) and beta cell function by gender in Korean populations with obesity. This study included 1,686 adults aged 20 or older using the 2010 Korea National Health and Nutrition Examination Survey (KNHANES) data, which represent national data in Korea. The key study results were as follows: First, in men, after adjusting for related variables (including body mass index), metabolic syndrome (p=0.005) and MSS (p=0.018) were inversely associated with the homeostatic model assessment of beta cell function (HOMA-B) values. Second, in women, after adjusting for related variables, metabolic syndrome (p=0.616) and MSS (p=0.929) were not associated with HOMA-B levels. In conclusion, metabolic syndrome and MSS were inversely associated with beta cell function in Korean men with obesity, but not in Korean women with obesity.
authors.affiliation: Department of Biomedical Laboratory Science, Hanlyo University, Gwangyang-si, Jeollanam-do 57764, South Korea.
authors.forename: Hyun
authors.initials: H
authors.lastname: Yoon
authors.forename: Dae Keun
authors.initials: DK
authors.lastname: Jeong
authors.forename: Kyu Su
authors.initials: KS
authors.lastname: Lee
authors.forename: Han Soo
authors.initials: HS
authors.lastname: Kim
authors.forename: Ae Eun
authors.initials: AE
authors.lastname: Moon
authors.forename: Jong
authors.initials: J
authors.lastname: Park
mesh_terms: D000328:Adult; D000368:Aged; D044466:Asian People / Q000706:statistics & numerical data; D003940:Diagnostic Techniques, Endocrine; D005260:Female; D006801:Humans; D050417:Insulin-Secreting Cells / Q000502:physiology*; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology / Q000503:physiopathology; D008875:Middle Aged; D009749:Nutrition Surveys; D009765:Obesity / Q000150:complications* / Q000503:physiopathology*; D056910:Republic of Korea; D012107:Research Design; D012737:Sex Factors