title: Arthroplasty for tenosynovial giant cell tumors.
abstract: Background and purpose - Tenosynovial giant cell tumors (t-GCTs) can behave aggressively locally and affect joint function and quality of life. The role of arthroplasty in the treatment of t-GCT is uncertain. We report the results of arthroplasty in t-GCT patients. Patients and methods - t-GCT patients (12 knee, 5 hip) received an arthroplasty between 1985 and 2015. Indication for arthroplasty, recurrences, complications, quality of life, and functional scores were evaluated after a mean follow-up time of 5.5 (0.2-15) years. Results - 2 patients had recurrent disease. 2 other patients had implant loosening. Functional scores showed poor results in almost half of the knee patients. 4 of the hip patients scored excellent and 1 scored fair. Quality of life was reduced in 1 or more subscales for 2 hip patients and for 5 knee patients. Interpretation - In t-GCT patients with extensive disease or osteoarthritis, joint arthroplasty is an additional treatment option. However, recurrences, implant loosening, and other complications do occur, even after several years.
authors.affiliation: a Department of Orthopedics , Radboud University Medical Center , Nijmegen , the Netherlands.
authors.forename: Floortje G M
authors.initials: FG
authors.lastname: Verspoor
authors.affiliation: a Department of Orthopedics , Radboud University Medical Center , Nijmegen , the Netherlands.
authors.forename: Gerjon
authors.initials: G
authors.lastname: Hannink
authors.affiliation: a Department of Orthopedics , Radboud University Medical Center , Nijmegen , the Netherlands.
authors.forename: Anouk
authors.initials: A
authors.lastname: Scholte
authors.affiliation: a Department of Orthopedics , Radboud University Medical Center , Nijmegen , the Netherlands.
authors.forename: Ingrid C M
authors.initials: IC
authors.lastname: Van Der Geest
authors.affiliation: a Department of Orthopedics , Radboud University Medical Center , Nijmegen , the Netherlands.
authors.forename: H W Bart
authors.initials: HW
authors.lastname: Schreuder
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D005544:Forecasting; D000070779:Giant Cell Tumor of Tendon Sheath / Q000175:diagnosis / Q000601:surgery*; D006621:Hip Joint / Q000000981:diagnostic imaging* / Q000601:surgery; D006801:Humans; D007719:Knee Joint / Q000000981:diagnostic imaging* / Q000601:surgery; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult