title: Enantioselective sulfoxidation reaction catalyzed by a G-quadruplex DNA metalloenzyme.
abstract: Enantioselective sulfoxidation reaction is achieved for the first time by a DNA metalloenzyme assembled with the human telomeric G-quadruplex DNA and Cu(ii)-4,4'-bimethyl-2,2'-bipyridine complex, and the mixed G-quadruplex architectures are responsible for the catalytic enantioselectivity and activity.
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn and University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China.
authors.forename: Mingpan
authors.initials: M
authors.lastname: Cheng
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn and University of Chinese Academy of Sciences, No. 19A Yuquan Road, Beijing, 100049, China.
authors.forename: Yinghao
authors.initials: Y
authors.lastname: Li
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn.
authors.forename: Jun
authors.initials: J
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn.
authors.forename: Guoqing
authors.initials: G
authors.lastname: Jia
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn.
authors.forename: Sheng-Mei
authors.initials: SM
authors.lastname: Lu
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn.
authors.forename: Yan
authors.initials: Y
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Catalysis, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, China. canli@dicp.ac.cn.
authors.forename: Can
authors.initials: C
authors.lastname: Li
mesh_terms: D055162:Biocatalysis; D054856:G-Quadruplexes; D006801:Humans; D008667:Metalloproteins / Q000737:chemistry / Q000378:metabolism*; D015394:Molecular Structure; D013237:Stereoisomerism; D013454:Sulfoxides / Q000737:chemistry / Q000378:metabolism*
chemical_list: D008667:Metalloproteins; D013454:Sulfoxides