title: [Preparation Technology of Huayu Xiaozhong Spray Films].
abstract: OBJECTIVE
  The extraction process and film-forming preparation technology of Huayu Xiaozhong spray film was optimized respectively by orthogonal design and central composite design/response surface method (CCD-RSM).
  
  
  METHODS
  With the extraction rate of amygdalin as the index, the orthogonal experiment was adopted for the optimization of extraction process. With the film-forming time, spraying effect, thickness and maintain time of spray film as the indexes, the dosages of PVA 1788, PVP k30 and glycerin as factors, the prescription was optimized by CCD-RSM.
  
  
  RESULTS
  The optimal extract processing was: immersing rude powder with 12 times of 60% ethanol for 24 hours. The optimal formula of Huayu Xiaozhong spray film was 5% of PVA 1788, 4.5% of glycerin and 5% of PVP-k30.
  
  
  CONCLUSIONS
  Under the optimum condition, the extraction efficiency of amygdalin is 96.7%. Under the optimum technological condition of preparation, the spray film meets the demand of quality.
authors.forename: Yu-lian
authors.initials: YL
authors.lastname: Zhu
authors.forename: Hua
authors.initials: H
authors.lastname: Huang
authors.forename: Ding
authors.initials: D
authors.lastname: Xia
authors.forename: Yuan-zhi
authors.initials: YZ
authors.lastname: Ren
mesh_terms: D004365:Drugs, Chinese Herbal; D000431:Ethanol; D005990:Glycerol; D013678:Technology, Pharmaceutical
chemical_list: D004365:Drugs, Chinese Herbal; D000431:Ethanol; D005990:Glycerol