title: Remote Biodegradation of Ge-Imogolite Nanotubes Controlled by the Iron Homeostasis of Pseudomonas brassicacearum.
abstract: The toxicity of high-aspect-ratio nanomaterials (HARNs) is often associated with oxidative stress. The essential nutrient Fe may also be responsible of oxidative stress through the production of reactive oxygen species. In the present study, it has been examined to what extent adding Fenton reaction promoting Fe impacted the toxicity of an alumino-germanate model HARN. Structural addition of only 0.95% wt Fe to Ge-imogolite not only alleviated the toxicity observed in the case of Fe-free nanotubes but also stimulated bacterial growth. This was attributed to the metabolization of siderophore-mobilized Fe from the nanotube structure. This was evidenced by the regulation of the homeostasis-monitoring intracellular Fe levels. This was accompanied by a biodegradation of the nanotubes approaching 40%, whereas the Fe-free nanomaterial remained nearly untouched.
authors.affiliation: Aix-Marseille Université, CNRS, IRD, CEREGE UM34 , 13545 Aix en Provence, France.|iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.|Laboratory of Microbial Ecology of the Rhizosphere and Extreme Environments (LEMIRE), Aix-Marseille Université, CEA, CNRS, UMR 7265 Biosciences and Biotechnology Institute of Aix-Marseille (BIAM), ECCOREV FR 3098, CEA/Cadarache , 13108 St-Paul-lez-Durance, France.
authors.forename: Astrid
authors.initials: A
authors.lastname: Avellan
authors.affiliation: Aix-Marseille Université, CNRS, IRD, CEREGE UM34 , 13545 Aix en Provence, France.|iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.
authors.forename: Melanie
authors.initials: M
authors.lastname: Auffan
authors.affiliation: Aix-Marseille Université, CNRS, IRD, CEREGE UM34 , 13545 Aix en Provence, France.|iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.
authors.forename: Armand
authors.initials: A
authors.lastname: Masion
authors.affiliation: Aix-Marseille Université, CNRS, IRD, CEREGE UM34 , 13545 Aix en Provence, France.|iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.
authors.forename: Clément
authors.initials: C
authors.lastname: Levard
authors.affiliation: Laboratory of Microbial Ecology of the Rhizosphere and Extreme Environments (LEMIRE), Aix-Marseille Université, CEA, CNRS, UMR 7265 Biosciences and Biotechnology Institute of Aix-Marseille (BIAM), ECCOREV FR 3098, CEA/Cadarache , 13108 St-Paul-lez-Durance, France.
authors.forename: Marie
authors.initials: M
authors.lastname: Bertrand
authors.affiliation: Aix-Marseille Université, CNRS, IRD, CEREGE UM34 , 13545 Aix en Provence, France.|iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.
authors.forename: Jérôme
authors.initials: J
authors.lastname: Rose
authors.affiliation: iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.|Laboratory of Microbial Ecology of the Rhizosphere and Extreme Environments (LEMIRE), Aix-Marseille Université, CEA, CNRS, UMR 7265 Biosciences and Biotechnology Institute of Aix-Marseille (BIAM), ECCOREV FR 3098, CEA/Cadarache , 13108 St-Paul-lez-Durance, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Santaella
authors.affiliation: iCEINT, International Consortium for the Environmental Implications of NanoTechology, CNRS, Duke University , Europôle de l'Arbois, 13545 Aix-en-Provence, France.|Laboratory of Microbial Ecology of the Rhizosphere and Extreme Environments (LEMIRE), Aix-Marseille Université, CEA, CNRS, UMR 7265 Biosciences and Biotechnology Institute of Aix-Marseille (BIAM), ECCOREV FR 3098, CEA/Cadarache , 13108 St-Paul-lez-Durance, France.
authors.forename: Wafa
authors.initials: W
authors.lastname: Achouak
mesh_terms: D001673:Biodegradation, Environmental; D006706:Homeostasis; D007501:Iron / Q000737:chemistry*; D043942:Nanotubes / Q000737:chemistry; D011549:Pseudomonas / Q000378:metabolism*
chemical_list: D007501:Iron