title: Effects of electromagnetic fields on osteoporosis: A systematic literature review.
abstract: Electromagnetic fields (EMFs) as a safe, effective and noninvasive treatment have been researched and used for many years in orthopedics, and the common use clinically is to promote fracture healing. The effects of EMFs on osteoporosis have not been well concerned. The balance between osteoblast and osteoclast activity as well as the balance between osteogenic differentiation and adipogenic differentiation of bone marrow mesenchymal stem cells plays an important role in the process of osteoporosis. A number of recent reports suggest that EMFs have a positive impact on the balances. In this review, we discuss the recent advances of EMFs in the treatment of osteoporosis from basic research to clinical study and introduce the possible mechanism. In addition, we presented future perspectives of application of EMFs for osteoporosis.
authors.affiliation: a Department of Gastroenterology , General Hospital of the Yangtse River Shipping , Hubei , P. R. China.
authors.forename: Rong
authors.initials: R
authors.lastname: Wang
authors.affiliation: b Department of Orthopedics , Tongji Hospital, Huazhong University of Science and Technology , Hubei , P. R. China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wu
authors.affiliation: b Department of Orthopedics , Tongji Hospital, Huazhong University of Science and Technology , Hubei , P. R. China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Yang
authors.affiliation: c Department of Obstetrics and Gynecology , Tongji Hospital, Huazhong University of Science and Technology , Hubei , P. R. China.
authors.forename: Mingyu
authors.initials: M
authors.lastname: Song
mesh_terms: D000818:Animals; D049109:Cell Proliferation / Q000528:radiation effects; D006801:Humans; D055909:Magnetic Field Therapy / Q000379:methods*; D010010:Osteoclasts / Q000473:pathology / Q000528:radiation effects; D010024:Osteoporosis / Q000473:pathology / Q000503:physiopathology / Q000628:therapy*
keywords: Electromagnetic fields; mechanism; osteoporosis