title: Data on respiratory variables in critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+).
abstract: The data show respiratory variables in 108 critically ill patients with acute respiratory failure placed on proportional assist ventilation with load adjustable gain factors (PAV+) after at least 36 h on passive mechanical ventilation. PAV+ was continued for 48 h until the patients met pre-defined criteria either for switching to controlled modes or for breathing without ventilator assistance. Data during passive mechanical ventilation and during PAV+ are reported. Data are acquired from the whole population, as well as from patients with and without acute respiratory distress syndrome. The reported variables are tidal volume, driving pressure (ΔP, the difference between static end-inspiratory plateau pressure and positive end-expiratory airway pressure), respiratory system compliance and resistance, and arterial blood gasses. The data are supplemental to our original research article, which described individual ΔP in these patients and examined how it related to ΔP when the same patients were ventilated with passive mechanical ventilation using the currently accepted lung-protective strategy "Driving pressure during assisted mechanical ventilation. Is it controlled by patient brain?" [1].
authors.affiliation: Intensive Care Medicine and University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece; Pulmonary Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece.
authors.forename: Dimitris
authors.initials: D
authors.lastname: Georgopoulos
authors.affiliation: Intensive Care Medicine and University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece.
authors.forename: Nectaria
authors.initials: N
authors.lastname: Xirouchaki
authors.affiliation: Pulmonary Department, University Hospital of Heraklion, Medical School, University of Crete, Heraklion, Crete, Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Tzanakis
authors.affiliation: Sleep Disorders Centre, Misericordia Health Centre, Winnipeg, Manitoba, Canada.
authors.forename: Magdy
authors.initials: M
authors.lastname: Younes
keywords: ARDS, Acute respiratory distress syndrome; CMV, Controlled mechanical ventilation (Passive mechanical ventilation); Compliance; Crs, Respiratory system compliance; CrsCMV, Respiratory system compliance during controlled mechanical ventilation; CrsPAV+, Respiratory system compliance during proportional assist ventilation with load adjustable gain factors; CrsPAV+aver, Average respiratory system compliance during the first 8-hour period of proportional assist ventilation with load adjustable gain factors; Driving pressure; PAV+, Proportional assist ventilation with load adjustable gain factors; PEEPi, Intrinsic positive end-expiratory airway pressure; PaCO2, Partial pressure of arterial CO2; Rmin, End-inspiratory airway resistance during controlled mechanical ventilation; Tidal volume; VT, Tidal volume; VTCMV, Tidal volume during controlled mechanical ventilation; VTPAV+, Tidal volume during proportional assist ventilation with load adjustable gain factors; VTPAV+aver, Average tidal volume during the first 8-h period of proportional assist ventilation with load adjustable gain factors; ΔP, Driving pressure; ΔPCMV, Driving pressure during controlled mechanical ventilation; ΔPPAV+, Driving pressure during proportional assist ventilation with load adjustable gain factors; ΔPPAV+aver, Average driving pressure during the first 8-h period of proportional assist ventilation with load adjustable gain factors