title: Methamphetamine-related brainstem haemorrhage.
abstract: We report the case of an otherwise healthy 29-year-old woman who presented with a brainstem haemorrhage following intravenous methamphetamine use. Extensive investigation did not reveal an underlying pathology, and the development of symptoms was temporally related to methamphetamine injection. Although intracerebral haemorrhage secondary to methamphetamine use is well documented, this report describes a haemorrhage within the brainstem which is a rare location. While animal studies have demonstrated the potential of methamphetamines to produce brainstem haemorrhages, there has only been one previous report describing a haemorrhage in this location due to amphetamine use in humans. We conclude with a brief discussion of the clinical features and aetiology of methamphetamine-related stroke.
authors.affiliation: Department of Surgery, Monash Medical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria 3800, Australia.
authors.forename: Zelia K
authors.initials: ZK
authors.lastname: Chiu
authors.affiliation: Department of Neurosurgery, Level 1, Old Baker Building, The Alfred Hospital, 55 Commercial Rd, Melbourne, Victoria 3004, Australia. Electronic address: i.bennett@alfred.org.au.
authors.forename: Iwan E
authors.initials: IE
authors.lastname: Bennett
authors.affiliation: Department of Surgery, Monash Medical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria 3800, Australia; Department of Neurosurgery, Level 1, Old Baker Building, The Alfred Hospital, 55 Commercial Rd, Melbourne, Victoria 3004, Australia.
authors.forename: Patrick
authors.initials: P
authors.lastname: Chan
authors.affiliation: Department of Surgery, Monash Medical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Victoria 3800, Australia; Department of Neurosurgery, Level 1, Old Baker Building, The Alfred Hospital, 55 Commercial Rd, Melbourne, Victoria 3004, Australia.
authors.forename: Jeffrey V
authors.initials: JV
authors.lastname: Rosenfeld
mesh_terms: D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging*; D001933:Brain Stem / Q000000981:diagnostic imaging*; D002543:Cerebral Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008694:Methamphetamine / Q000009:adverse effects*
chemical_list: D008694:Methamphetamine
keywords: Brainstem haemorrhage; Methamphetamine; Stroke