title: Chronic l-citrulline supplementation improves cardiac sympathovagal balance in obese postmenopausal women: A preliminary report.
abstract: The present study evaluated the impact of chronic l-citrulline (L-cit) supplementation on resting heart rate variability (HRV) and blood pressure (BP) in obese postmenopausal women. Participants were randomly assign to either an L-cit group (n=12) or a control group (n=11). HRV and BP were measured before and after 8weeks. There were significant decreases (P<0.05) in nLF (sympathetic activity), LnLF/LnHF (sympathovagal balance), and BP as well as a significant increase (P<0.05) in nHF (vagal tone) following L-cit compared with no changes after control. Our findings indicate that L-cit supplementation improves sympathovagal balance in obese postmenopausal women.
authors.affiliation: Department of Health and Human Performance, Marymount University, 2807 North Glebe Road, Arlington, VA 22207, USA. Electronic address: awong@marymount.edu.
authors.forename: Alexei
authors.initials: A
authors.lastname: Wong
authors.affiliation: Department of Philosophy, Nosov Magnitogorsk State Technical University, 38 Lenin ave., Magnitogorsk, Chelyabinsk Region 455000, Russia.
authors.forename: Oksana
authors.initials: O
authors.lastname: Chernykh
authors.affiliation: Department of Nutrition, Food and Exercise Sciences, Florida State University, 120 Convocation Way, Tallahassee, FL 32306, USA.
authors.forename: Arturo
authors.initials: A
authors.lastname: Figueroa
mesh_terms: D000368:Aged; D001794:Blood Pressure / Q000187:drug effects / Q000502:physiology; D002956:Citrulline / Q000494:pharmacology*; D005260:Female; D006321:Heart / Q000187:drug effects* / Q000503:physiopathology; D006339:Heart Rate / Q000187:drug effects* / Q000502:physiology; D006801:Humans; D008875:Middle Aged; D009765:Obesity / Q000188:drug therapy* / Q000503:physiopathology; D017698:Postmenopause / Q000502:physiology; D013564:Sympathetic Nervous System / Q000187:drug effects* / Q000503:physiopathology; D014630:Vagus Nerve / Q000187:drug effects* / Q000503:physiopathology
chemical_list: D002956:Citrulline
keywords: Heart rate variability; Sympathovagal balance; l-citrulline