title: Multichannel perimetric alterations in systemic lupus erythematosus treated with hydroxychloroquine.
abstract: Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease of unknown etiology with many clinical manifestations. We report the first case of SLE in which visual alterations were evaluated with multichannel perimetry. Some achromatic and color vision alterations may be present in SLE, especially when treated with hydroxychloroquine. The sensitivity losses detected in the chromatic channels in the central zone of the visual field were consistent with the results of the FM 100 Hue color test. Likewise, the multichannel perimetry detected sensitivity losses in the parafoveal area for both chromatic channels, especially for the blue-yellow.
authors.affiliation: Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain; Department of Ophthalmology (OFTALMAR), Medimar International Hospital, Alicante, Spain; Foundation for the Visual Quality (Fundación para la Calidad Visual, FUNCAVIS), Alicante, Spain.
authors.forename: David P
authors.initials: DP
authors.lastname: Piñero
authors.affiliation: Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain.
authors.forename: Begoña
authors.initials: B
authors.lastname: Monllor
authors.affiliation: Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain.
authors.forename: Vicente J
authors.initials: VJ
authors.lastname: Camps
authors.affiliation: Grupo de Óptica y Percepción Visual (GOPV), Department of Optics, Pharmacology and Anatomy, University of Alicante, Spain. Electronic address: dolores.fez@ua.es.
authors.forename: Dolores
authors.initials: D
authors.lastname: de Fez
mesh_terms: D003117:Color Vision Defects / Q000139:chemically induced*; D004791:Enzyme Inhibitors / Q000009:adverse effects*; D005260:Female; D006801:Humans; D006886:Hydroxychloroquine / Q000009:adverse effects*; D008180:Lupus Erythematosus, Systemic / Q000188:drug therapy*; D008875:Middle Aged; D058609:Visual Field Tests / Q000379:methods; D014794:Visual Fields / Q000187:drug effects*
chemical_list: D004791:Enzyme Inhibitors; D006886:Hydroxychloroquine
keywords: Contrast sensitivity; Hydroxychloroquine maculopathy; Lupus disease; Lupus eritematoso; Maculopatía por hidroxicloroquina; Multichannel perimetry; Perimetría multicanal; Sensibilidad al contraste; Visual pathways; Vías visuales