title: DNA-catalyzed glycosylation using aryl glycoside donors.
abstract: We report the identification by in vitro selection of Zn(2+)/Mn(2+)-dependent deoxyribozymes that glycosylate the 3'-OH of a DNA oligonucleotide. Both β and α anomers of aryl glycosides can be used as the glycosyl donors. Individual deoxyribozymes are each specific for a particular donor anomer.
authors.affiliation: Department of Chemistry, University of Illinois at Urbana-Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, USA. scott@scs.illinois.edu.
authors.forename: Anthony R
authors.initials: AR
authors.lastname: Hesser
authors.forename: Benjamin M
authors.initials: BM
authors.lastname: Brandsen
authors.forename: Shannon M
authors.initials: SM
authors.lastname: Walsh
authors.forename: Puzhou
authors.initials: P
authors.lastname: Wang
authors.forename: Scott K
authors.initials: SK
authors.lastname: Silverman
mesh_terms: D055162:Biocatalysis; D021881:DNA, Catalytic / Q000737:chemistry / Q000378:metabolism*; D006027:Glycosides / Q000737:chemistry / Q000378:metabolism*; D006031:Glycosylation
chemical_list: D021881:DNA, Catalytic; D006027:Glycosides