title: Secondary metabolites of Xylaria sp., an endophytic fungus from Taxus mairei.
abstract: One new metabolite 3,7-dimethyl-9-(-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)nona-1,6-dien-3-ol, together with nine known compounds, were isolated from the strain Xylaria sp., an endophytic fungus of Taxus mairei. Their structures were deduced from 1D and 2D NMR data. In vitro cytotoxicity and antibacterial activity of these compounds were evaluated. Some of them exhibited substantial activity.
authors.affiliation: a Medical College , Xiamen University , Xiamen , China.|b School of Life Sciences , Xiamen University , Xiamen , China.
authors.forename: Xiao
authors.initials: X
authors.lastname: Lin
authors.affiliation: b School of Life Sciences , Xiamen University , Xiamen , China.|c School of Life Sciences , Ningxia University , Yinchuan , China.
authors.forename: Miao
authors.initials: M
authors.lastname: Yu
authors.affiliation: d School of Pharmaceutical Sciences , Xiamen University , Xiamen , China.
authors.forename: Ting
authors.initials: T
authors.lastname: Lin
authors.affiliation: b School of Life Sciences , Xiamen University , Xiamen , China.
authors.forename: Lianru
authors.initials: L
authors.lastname: Zhang
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000903:Antibiotics, Antineoplastic / Q000494:pharmacology; D004148:Dioxolanes / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D060026:Endophytes / Q000378:metabolism*; D005285:Fermentation; D006367:HeLa Cells; D006801:Humans; D019906:Nuclear Magnetic Resonance, Biomolecular; D064210:Secondary Metabolism; D020946:Taxus / Q000382:microbiology*; D013098:Xylariales / Q000378:metabolism*
chemical_list: C000617459:3,7-dimethyl-9-(-2,2,5,5-tetramethyl-1,3-dioxolan-4-yl)nona-1,6-dien-3-ol; D000900:Anti-Bacterial Agents; D000903:Antibiotics, Antineoplastic; D004148:Dioxolanes
keywords: Metabolites; Taxus mairei; Xylaria sp