title: Treatment of abdominal wall hernia with suture, or polypropylene, or collagen prosthesis.
abstract: OBJECTIVE
  To develop an experimental model for incisional hernias and to compare morphological and functional aspects of hernia repairs by suture, polypropylene mesh and collagen mesh.
  
  
  METHODS
  A defect measuring 7cm x 2cm was created in the anterior abdominal of 28 New Zealand male rabbits, divided into four groups (n = 7): (1) control, (2) suture of the anterior sheath of the rectus abdominal muscle, (3) setting of polypropylene mesh, and (4) setting of collagen mesh. On the 90th postoperative day, the animals were examined to verify the presence of incisional hernia. Samples of abdominal wall and scar were collected for histological study.
  
  
  RESULTS
  Incisional hernia was identified in 85.7% of the control group, 57.1% of the suture group, 42.9% of the collagen mesh group, and none in the polypropylene mesh group (p = 0.015). Mesh exposure could be identified in 71.4% of the animals in group 3 and in no animal in group 4 (p = 0.021). The polypropylene mesh is effective in the treatment of abdominal wall defects, causing an intense inflammatory reaction.
  
  
  CONCLUSIONS
  The collagen mesh is biocompatible, producing a minimal inflammatory reaction, but fails in the treatment of abdominal wall defects.
authors.affiliation: PhD, Associate Professor, General Surgeon, Department of Surgery, Instituto de Ensino e Pesquisa da Santa Casa, Belo Horizonte-MG, Brazil. Intellectual and scientific content of the study, design the protocol, technical procedures, manuscript writing.
authors.forename: Diego Paim Carvalho
authors.initials: DP
authors.lastname: Garcia
authors.affiliation: MD, General and Trauma Surgeon, Hospital Universitário São José, Belo Horizonte-MG, Brazil. Acquisition and interpretation of data, statistical analysis, design the protocol, technical procedures, macroscopic and histopathological examinations.
authors.forename: Clarissa
authors.initials: C
authors.lastname: Santos
authors.affiliation: MD, General Surgeon, Hospital Felício Rocho, Belo Horizonte-MG, Brazil. Acquisition and interpretation of data, statistical analysis, design the protocol, technical procedures, macroscopic and histopathological examinations.
authors.forename: Pablo Nelson do Valle
authors.initials: PN
authors.lastname: Hubner
authors.affiliation: MD, General Surgeon, Hospital Felício Rocho, Belo Horizonte-MG, Brazil. Acquisition and interpretation of data, statistical analysis, design the protocol, technical procedures, macroscopic and histopathological examinations.
authors.forename: Thiago de Almeida
authors.initials: Tde A
authors.lastname: Furtado
authors.affiliation: PhD, Full Professor, Department of Surgery, Faculdade de Medicina, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte-MG, Brazil. Intellectual and scientific content of the study, design the protocol, provided guidelines for the surgical interventions, supervised all phases of the study.
authors.forename: Andy
authors.initials: A
authors.lastname: Petroianu
authors.affiliation: Fellow of Surgery, Hospital Felício Rocho, Belo Horizonte-MG, BrazilAcquisition and interpretation of data, statistical analysis, manuscript revision.
authors.forename: Luiza Ohasi de
authors.initials: LO
authors.lastname: Figueiredo
authors.affiliation: PhD, Associate Professor, General Surgeon, Department of Surgery, Faculdade de Medicina, UFMG, and Instituto de Ensino e Pesquisa da Santa Casa, Belo Horizonte-MG, Brazil. Acquisition and interpretation of data, statistical analysis, design the protocol, technical procedures.
authors.forename: Luiz Ronaldo
authors.initials: LR
authors.lastname: Alberti
mesh_terms: D034861:Abdominal Wall / Q000473:pathology / Q000601:surgery*; D000818:Animals; D003094:Collagen / Q000627:therapeutic use; D015743:Giant Cells, Foreign-Body / Q000473:pathology; D000069290:Incisional Hernia / Q000601:surgery*; D007249:Inflammation / Q000473:pathology; D008297:Male; D023421:Models, Animal; D011126:Polypropylenes / Q000009:adverse effects; D011183:Postoperative Complications / Q000473:pathology; D019919:Prosthesis Implantation / Q000009:adverse effects / Q000295:instrumentation; D011817:Rabbits; D013526:Surgical Mesh / Q000009:adverse effects; D013537:Sutures / Q000009:adverse effects*
chemical_list: D011126:Polypropylenes; D003094:Collagen