title: [Periodontal tissue engineering by FGF-2:Its present status and future outlook].
abstract: Periodontitis remains highly prevalent all over the world and can lead to loss of the affected teeth. Thus, establishing a brand-new treatment that enables the regeneration and rebuilding of periodontal tissue destroyed by periodontitis represents a task of tremendous importance. Our pre-clinical studies and clinical trials suggested that efficacy is expected from basic fibroblast growth factor(FGF-2)in stimulating regeneration of periodontal tissue. Development of the osteoconductive carrier for FGF-2 drug will further extend the indications in the field of dental medicine.
authors.affiliation: Department of Periodontology,Osaka University Graduate School of Dentistry, Japan.
authors.forename: Shinya
authors.initials: S
authors.lastname: Murakami
mesh_terms: D016222:Fibroblast Growth Factor 2 / Q000235:genetics / Q000378:metabolism*; D006801:Humans; D009059:Mouth Diseases / Q000628:therapy; D010519:Periodontium; D012038:Regeneration; D013234:Stem Cells; D023822:Tissue Engineering
chemical_list: D016222:Fibroblast Growth Factor 2