title: The utility of noninvasive nasal positive pressure ventilators for optimizing oxygenation during rapid sequence intubation.
abstract: OBJECTIVE
  The objective of the study is to investigate the feasibility of noninvasive nasal positive pressure ventilation (NINPPV) for optimizing oxygenation during the rapid sequence intubation in critically ill patients.
  
  
  METHODS
  A prospective, observational study was performed in an emergency department. Noninvasive nasal positive pressure ventilation was applied in the preoxygenation step and maintained until successful intubation. A pulse oximetry (Spo2) was continuously monitored throughout the procedure and recorded 5 times. The degree of interfering was surveyed with 10-point Likert scale.
  
  
  RESULTS
  Thirty patients were enrolled. The most of enrolled patients were diagnosed as pneumonia, acute heart failure, and traumatic brain injury. The Spo2 was increased to 100% (98%-100%) at the time of starting endotracheal intubation with NINPPV and maintained as 97% (95%-100%) until successful intubation (P< .001). Total apnea duration was 195 seconds (190-196). The degree of interfering intubation was 1 (0-1).
  
  
  CONCLUSIONS
  Noninvasive nasal positive pressure ventilation would be useful for optimizing oxygenation during rapid sequence intubation.
authors.affiliation: Department of Emergency Medicine, Busan Baik Hospital, Inje University, Republic of Korea.
authors.forename: Tae Hoon
authors.initials: TH
authors.lastname: Kim
authors.affiliation: Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Republic of Korea.
authors.forename: Sung Oh
authors.initials: SO
authors.lastname: Hwang
authors.affiliation: Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Republic of Korea.
authors.forename: Yong Sung
authors.initials: YS
authors.lastname: Cha
authors.affiliation: Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Republic of Korea.
authors.forename: Oh Hyun
authors.initials: OH
authors.lastname: Kim
authors.affiliation: Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Republic of Korea.
authors.forename: Kang Hyun
authors.initials: KH
authors.lastname: Lee
authors.affiliation: Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Republic of Korea.
authors.forename: Hyun
authors.initials: H
authors.lastname: Kim
authors.affiliation: Department of Emergency Medicine, Yonsei University Wonju College of Medicine, Republic of Korea. Electronic address: chaemp@yonsei.ac.kr.
authors.forename: Kyoung-Chul
authors.initials: KC
authors.lastname: Cha
mesh_terms: D000368:Aged; D016638:Critical Illness / Q000628:therapy*; D004636:Emergency Service, Hospital; D005260:Female; D006801:Humans; D000860:Hypoxia / Q000378:metabolism / Q000628:therapy*; D007442:Intubation, Intratracheal / Q000379:methods*; D008297:Male; D008875:Middle Aged; D063087:Noninvasive Ventilation / Q000379:methods*; D009666:Nose; D010092:Oximetry; D010100:Oxygen / Q000378:metabolism*; D011446:Prospective Studies
chemical_list: D010100:Oxygen