title: Bullous Kaposiform Hemangioendothelioma Masquerading as Aplasia Cutis Congenita.
abstract: We present the case of a male infant with violaceous bullae on the scalp that were initially thought to be bullous aplasia cutis but at 3 months of age were diagnosed as a kaposiform hemangioendothelioma. This diagnosis should be considered when evaluating newborns with bullous plaques on the scalp that do not heal in the first 2-3 weeks of life. Kaposiform hemangioendothelioma (KHE) is a rare vascular tumor that typically presents as a violaceous to purpuric plaque at birth or early infancy. It may be associated with Kasabach-Merritt phenomenon (KMP), a potentially life-threatening consumptive coagulopathy.
authors.affiliation: Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.
authors.forename: Aaron J
authors.initials: AJ
authors.lastname: Steen
authors.affiliation: Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.|Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
authors.forename: Joseph H
authors.initials: JH
authors.lastname: Shin
authors.affiliation: Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.|Division of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
authors.forename: Nicole C
authors.initials: NC
authors.lastname: Pace
authors.affiliation: Department of Pathology, Emory University Hospital, Atlanta, Georgia.
authors.forename: Mark
authors.initials: M
authors.lastname: Edgar
authors.affiliation: Department of Pathology, Emory University Hospital, Atlanta, Georgia.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Clay
authors.affiliation: Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.|Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Linos
authors.affiliation: Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire.|Division of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.|Department of Pathology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire.
authors.forename: Dorothea T
authors.initials: DT
authors.lastname: Barton
authors.affiliation: Geisel School of Medicine, Dartmouth College, Hanover, New Hampshire. julianne.a.mann@hitchcock.org.|Division of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire. julianne.a.mann@hitchcock.org.
authors.forename: Julianne A
authors.initials: JA
authors.lastname: Mann
mesh_terms: D003937:Diagnosis, Differential; D004476:Ectodermal Dysplasia / Q000175:diagnosis*; D006390:Hemangioendothelioma / Q000175:diagnosis*; D006801:Humans; D007223:Infant; D059885:Kasabach-Merritt Syndrome / Q000175:diagnosis*; D008297:Male; D012514:Sarcoma, Kaposi / Q000175:diagnosis*; D012535:Scalp