title: Donor T Cells May Enhance Immunotherapy.
abstract: A proof-of-principle study demonstrates that T cells from healthy donors recognize many tumor neoantigens overlooked by a patient's own immune system. Outsourcing neoantigen-induced immune reactivity to donor T cells could be a feasible way to bolster patients' response to immunotherapy.
mesh_terms: D000951:Antigens, Neoplasm / Q000378:metabolism*; D006801:Humans; D016219:Immunotherapy, Adoptive; D009369:Neoplasms / Q000276:immunology / Q000628:therapy*; D013601:T-Lymphocytes / Q000276:immunology*; D014019:Tissue Donors; D014184:Transplantation, Homologous
chemical_list: D000951:Antigens, Neoplasm