title: Current status of auxiliary partial orthotopic liver transplantation for acute liver failure.
abstract: Auxiliary partial orthotopic liver transplantation (APOLT) is a technique of liver transplantation (LT) where a partial liver graft is implanted in an orthotopic position after leaving behind a part of the native liver. APOLT was previously considered technically challenging with results inferior to orthotopic liver transplantation. Results of this procedure have continued to improve with improving surgical techniques and a better understanding of the natural history of acute liver failure (ALF) and liver regeneration. The procedure is being increasingly accepted as a valid treatment option for ALF-especially in children. This article reviews the historical background to this operation, advances in the technique, and its current place in the management of ALF. Liver Transplantation 22 1265-1274 2016 AASLD.
authors.affiliation: Institute of Liver Studies, King's College Hospital, London, United Kingdom.|Institute of Liver Disease and Transplantation, Global Hospital, Chennai, India.|National Foundation for Liver Research, Chennai, India.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Rela
authors.affiliation: Institute of Liver Disease and Transplantation, Global Hospital, Chennai, India.
authors.forename: Ilankumaran
authors.initials: I
authors.lastname: Kaliamoorthy
authors.affiliation: Institute of Liver Disease and Transplantation, Global Hospital, Chennai, India.|National Foundation for Liver Research, Chennai, India.
authors.forename: Mettu Srinivas
authors.initials: MS
authors.lastname: Reddy
mesh_terms: D000328:Adult; D000367:Age Factors; D064591:Allografts / Q000098:blood supply; D002648:Child; D006084:Graft Rejection / Q000517:prevention & control; D006801:Humans; D007165:Immunosuppression Therapy; D008099:Liver / Q000098:blood supply; D017114:Liver Failure, Acute / Q000401:mortality / Q000601:surgery*; D008115:Liver Regeneration; D016031:Liver Transplantation / Q000009:adverse effects / Q000379:methods*; D018579:Patient Selection; D011182:Postoperative Care / Q000379:methods; D055815:Young Adult