title: Intracranial Hypotension as A Rare Complication of Vertebroplasty: A Case Report.
abstract: BACKGROUND
  Vertebral compression fracture is one of the frequent complications of osteoporosis. Percutaneous vertebroplasty (PVP) has been applied in the treatment of osteoporotic vertebral compression fractures, multiple myelomas and vertebral metastatic lesions. Complications of the procedure include bleeding at the puncture site, local infection, cement leakage in the vertebral canal and intervertebral foramen. Cerebrospinal fluid leakage after the procedure was rarely mentioned in the literature.
  
  
  METHODS
  A 51-year-old healthy female patient has no neurologic or orthopedic illness before. She suffered from severe low back pain since 10 days ago after some exercise. She has back pain with radiating to bilateral subcostal areas. The pain aggravated by bending forward. X ray of spine showed T12 vertebral body compression fracture. MRI demonstrated compression fracture at T12 with bone marrow edema and increased bone marrow enhancement. Bone mineral density checked by Dualenergy X-ray absorptiometry revealed osteopenia. The symptoms were not relieved by conservative treatments and she received vertebroplasty for pain relief. The operation course was smooth, but she started to suffer from orthostatic headache after the procedure. Spinal MRI revealed fluid accumulation at posterior epidural space of T11-12-L1 and CSF leakage was impressed. Intracranial hypotension related to CSF leakage was diagnosed according to the Diagnostic criteria formulated by Schievink, et al (2008). After hydration and bed-rest, her symptoms improved gradually without epidural blood patch.
  
  
  CONCLUSIONS
  Our report highlights the possibility and importance of intracranial hypotension related to CSF leakage after vertebroplasty. Clinicians should be alert to this complication.
authors.affiliation: Department of Neurology, EDa hospital, Kaohsiung, Taiwan.
authors.forename: Yen-Wen
authors.initials: YW
authors.lastname: Chen
authors.affiliation: Department of Psychiatry, Tsyr-Huey Mental Hospital, Kaohsiung Jen-Ai's Home, Taiwan.
authors.forename: Ping-Tao
authors.initials: PT
authors.lastname: Tseng
authors.affiliation: Department of Neurology, EDa hospital, Kaohsiung, Taiwan.
authors.forename: Huan-Wen
authors.initials: HW
authors.lastname: Tsui
authors.affiliation: Department of Neurology, EDa hospital, Kaohsiung, Taiwan.
authors.forename: Shih-Pin
authors.initials: SP
authors.lastname: Hsu
authors.affiliation: Department of Neurology, EDa hospital, Kaohsiung, Taiwan.
authors.forename: Hung-Chang
authors.initials: HC
authors.lastname: Kuo
mesh_terms: D065634:Cerebrospinal Fluid Leak / Q000150:complications; D005260:Female; D006801:Humans; D019585:Intracranial Hypotension / Q000209:etiology*; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology*; D054854:Vertebroplasty / Q000009:adverse effects*