title: Mitochondrial lipid transport and biosynthesis: A complex balance.
abstract: Little is known about how mitochondrial lipids reach inner membrane-localized metabolic enzymes for phosphatidylethanolamine synthesis. Aaltonen et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201602007) and Miyata et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201601082) now report roles for two mitochondrial complexes, Ups2-Mdm35 and mitochondrial contact site and cristae organizing system, in the biosynthesis and transport of mitochondrial lipids.
authors.affiliation: Institut de Pharmacologie Moléculaire et Cellulaire, Université de Nice Sophia-Antipolis, 06560 Valbonne, France Centre National de la Recherche Scientifique, 06560 Valbonne, France mesmin@ipmc.cnrs.fr.
authors.forename: Bruno
authors.initials: B
authors.lastname: Mesmin
mesh_terms: D000818:Animals; D001692:Biological Transport; D006801:Humans; D050356:Lipid Metabolism; D008055:Lipids / Q000096:biosynthesis*; D008928:Mitochondria / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000378:metabolism; D008954:Models, Biological; D012441:Saccharomyces cerevisiae / Q000378:metabolism
chemical_list: D008055:Lipids