title: Objectively Measured Steps/Day in Patients With Chronic Obstructive Pulmonary Disease: A Systematic Review and Meta-Analysis.
abstract: Although individual studies have reported on the number of steps/day taken by individuals with chronic obstructive pulmonary disease (COPD), this evidence has not been systematically reviewed or synthesized.
  
  
  
  MEDLINE and PsycINFO were searched for studies reporting objectively-measured steps/day and percent predicted forced expiratory volume in 1 second (FEV1%) in patients with COPD. Meta-analyses were used to estimate steps/day across studies, while metaregression was used to estimate between-study variance based on clinical and demographic factors (year and location of study, activity monitor brand, number of days wearing the monitor, whether participants were about to enter pulmonary rehabilitation, 6-minute walk distance (6MWD), FEV1%, age, and sex).
  
  
  
  38 studies including 2621 participants met inclusion criteria. The pooled mean estimate was 4579 steps/day (95% CI:4310 to 5208) for individuals with COPD. Only 6MWD, FEV1% and whether patients were about to undergo pulmonary rehabilitation explained a significant portion of the variance (P < 0.1) in univariate meta-regression. In a multivariate model including the above risk factors, only FEV1% was associated with steps/day after adjustment for other covariates.
  
  
  
  These results indicate that patients with COPD achieve extremely low levels of physical activity as assessed by steps/day, and that severity of airflow obstruction is associated with activity level.
authors.forename: Travis
authors.initials: T
authors.lastname: Saunders
authors.forename: Nerissa
authors.initials: N
authors.lastname: Campbell
authors.forename: Timothy
authors.initials: T
authors.lastname: Jason
authors.forename: Gail
authors.initials: G
authors.lastname: Dechman
authors.forename: Paul
authors.initials: P
authors.lastname: Hernandez
authors.forename: Kara
authors.initials: K
authors.lastname: Thompson
authors.forename: Chris M
authors.initials: CM
authors.lastname: Blanchard
mesh_terms: D061725:Accelerometry; D000368:Aged; D015444:Exercise; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000534:rehabilitation*; D016138:Walking
keywords: accelerometer; ambulation; exercise; pedometer; physical activity; walking