title: Human Induced Pluripotent Stem Cells as a Platform for Personalized and Precision Cardiovascular Medicine.
abstract: Human induced pluripotent stem cells (hiPSCs) have revolutionized the field of human disease modeling, with an enormous potential to serve as paradigm shifting platforms for preclinical trials, personalized clinical diagnosis, and drug treatment. In this review, we describe how hiPSCs could transition cardiac healthcare away from simple disease diagnosis to prediction and prevention, bridging the gap between basic and clinical research to bring the best science to every patient.
authors.affiliation: Stanford Cardiovascular Institute, Department of Medicine, Division of Cardiology, and Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: Elena
authors.initials: E
authors.lastname: Matsa
authors.affiliation: Stanford Cardiovascular Institute, Department of Medicine, Division of Cardiology, and Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: John H
authors.initials: JH
authors.lastname: Ahrens
authors.affiliation: Stanford Cardiovascular Institute, Department of Medicine, Division of Cardiology, and Institute of Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford, California.
authors.forename: Joseph C
authors.initials: JC
authors.lastname: Wu
mesh_terms: D002318:Cardiovascular Diseases / Q000628:therapy*; D006801:Humans; D057026:Induced Pluripotent Stem Cells; D057285:Precision Medicine