title: Fabrication of 3D honeycomb-like porous polyurethane-functionalized reduced graphene oxide for detection of dopamine.
abstract: A three dimensional reduced graphene oxide/polyurethane (RGO-PU) porous material with connected pores was prepared by physical adsorption of RGO onto the surface of porous PU. The porous PU was prepared by directional melt crystallization of a solvent, which produced high pores with controlled orientation. The prepared RGO-PU was characterized by scanning electron microscopy, spectroscopy and electro-chemical methods. The RGO-PU porous material revealed better electrochemical performance, which might be attributed to the robust structure, superior conductivity, large surface area, and good flexibility. Differential pulse voltammetry (DPV) analysis of DA using the RGO-PU exhibited a linear response range over a wide DA concentration of 100-1150pM, with the detection limit of 1pM. This sensor exhibited outstanding anti-interference ability towards co-existing molecules with good stability, sensitivity, and reproducibility. Furthermore, the fabricated sensor was successfully applied for the quantitative analysis of DA in human serum and urine samples with acceptable recovery, which indicates its feasibility for practical application.
authors.affiliation: Department of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro, Jung-gu, Seoul 04620, Republic of Korea.
authors.forename: A T Ezhil
authors.initials: ATE
authors.lastname: Vilian
authors.affiliation: Department of Chemical Engineering and Materials Science, Chung-Ang University, 221 Heukseok-dong, Dongjak-gu, Seoul 06974, South Korea.
authors.forename: Suyeong
authors.initials: S
authors.lastname: An
authors.affiliation: Department of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Republic of Korea.
authors.forename: Sang Rak
authors.initials: SR
authors.lastname: Choe
authors.affiliation: Department of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Republic of Korea.
authors.forename: Cheol Hwan
authors.initials: CH
authors.lastname: Kwak
authors.affiliation: Department of Biological Engineering, Inha University, 100 Inha-ro, Nam-gu, Incheon 22212, Republic of Korea. Electronic address: yunsuk.huh@inha.ac.kr.
authors.forename: Yun Suk
authors.initials: YS
authors.lastname: Huh
authors.affiliation: Department of Chemical Engineering and Materials Science, Chung-Ang University, 221 Heukseok-dong, Dongjak-gu, Seoul 06974, South Korea. Electronic address: jong@cau.ac.kr.
authors.forename: Jonghwi
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Energy and Materials Engineering, Dongguk University-Seoul, 30 Pildong-ro, Jung-gu, Seoul 04620, Republic of Korea. Electronic address: ykenergy@dongguk.edu.
authors.forename: Young-Kyu
authors.initials: YK
authors.lastname: Han
mesh_terms: D065966:Absorption, Physicochemical; D001672:Biocompatible Materials / Q000138:chemical synthesis; D015374:Biosensing Techniques / Q000295:instrumentation; D003217:Conductometry / Q000295:instrumentation*; D004298:Dopamine / Q000032:analysis / Q000097:blood* / Q000652:urine*; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006108:Graphite / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D058608:Nanopores / Q000648:ultrastructure; D010084:Oxidation-Reduction; D010087:Oxides / Q000737:chemistry; D011140:Polyurethanes / Q000737:chemistry*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D001672:Biocompatible Materials; D010087:Oxides; D011140:Polyurethanes; D006108:Graphite; D004298:Dopamine
keywords: Dopamine; Electrocatalysis; Electrochemical sensor; Polyurethane; Reduced graphene oxide