title: Stereoselective Synthesis of Southern Fragment of Hantupeptin A.
abstract: The stereoselective synthesis of the southern fragment (C21-C41) of Hantupeptin A is described. The required stereochemistry of β-hydroxy-α-methyl acid unit was accomplished through the Aldol reaction using Evan's chiral auxiliary followed by the installation of the terminal alkyne with Ohira-Bestmann reagent.
authors.forename: Avula
authors.initials: A
authors.lastname: Srinivas
authors.forename: Malladi
authors.initials: M
authors.lastname: Sunitha
authors.forename: Chakunta Govind
authors.initials: CG
authors.lastname: Rao
mesh_terms: D047630:Depsipeptides / Q000138:chemical synthesis* / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D013237:Stereoisomerism
chemical_list: D047630:Depsipeptides; C534924:hantupeptin A