title: Enhanced MRI and 18F-FDG PET/CT Findings of Primary Central Nervous System Lymphoma Mimicking Encephalitis.
abstract: We present a case of 64-year-old man with primary central nervous system lymphoma that mimicked encephalitis on enhanced MRI and F-FDG PET/CT imaging. The initial and follow-up MRI showed gradually spread high-intensity patches with nonenhancement in cortices and subcortices, while the F-FDG imaging observed mild and inhomogeneous uptake in the corresponding cerebral area particularly in the splenium of corpus callosum. This case indicates that atypical primary central nervous system lymphoma should be noted in differential diagnosis of cerebral disseminated lesions with nonenhancement in MRI or with obscure uptake of F-FDG in PET imaging (especially involving the midline of the brain).
authors.affiliation: From the *PET Center and †Department of Neurology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China.
authors.forename: Jingjie
authors.initials: J
authors.lastname: Ge
authors.forename: Chuantao
authors.initials: C
authors.lastname: Zuo
authors.forename: Yihui
authors.initials: Y
authors.lastname: Guan
authors.forename: Guixian
authors.initials: G
authors.lastname: Zhao
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging / Q000378:metabolism; D016543:Central Nervous System Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D003937:Diagnosis, Differential; D004660:Encephalitis / Q000000981:diagnostic imaging*; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging* / Q000378:metabolism; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography
chemical_list: D019788:Fluorodeoxyglucose F18