title: A novel device to create consistent deep dermal burns in a porcine model.
abstract: We conducted this study to evaluate a novel device to create a consistent and reproducible deep partial thickness burn in a porcine model. A thermostatically controlled, heated aluminium disc device was fashioned by the Biomedical Department of our institution. Contact burns were made on the flank of two Great White pigs by applying the device heated to 92°C at intervals of 5, 10, 15 and 20 seconds to four separate test areas area of skin. Biopsies for histological analysis of burn depth were taken on day 0 at 10 minutes post burn and on day 8. Biopsies taken at day 0 revealed superficial to mid-dermal burns, with minimal dermal edema and necrosis. Those from day 8 showed mid to deep dermal edema and necrosis in all four test areas following a 20 second contact duration burn. The new contact burn device was able to create a consistent deep dermal burn after 20 seconds of contact. We anticipate that this new device could be used to investigate the development of hypertrophic scarring in a porcine model.
authors.affiliation: Department of Paediatric Surgery, The Children's Hospital Burns Research Institute and Burns Unit, The Children's Hospital at WestmeadNew South Wales, Australia; Sydney Medical School, The University of SydneyNew South Wales, Australia.
authors.forename: Seema
authors.initials: S
authors.lastname: Menon
authors.affiliation: Department of Paediatric Surgery, The Children's Hospital Burns Research Institute and Burns Unit, The Children's Hospital at Westmead New South Wales, Australia.
authors.forename: Queenie
authors.initials: Q
authors.lastname: Chan
authors.affiliation: Department of Paediatric Surgery, The Children's Hospital Burns Research Institute and Burns Unit, The Children's Hospital at Westmead New South Wales, Australia.
authors.forename: Monique
authors.initials: M
authors.lastname: Bertinetti
authors.affiliation: Department of Paediatric Surgery, The Children's Hospital Burns Research Institute and Burns Unit, The Children's Hospital at WestmeadNew South Wales, Australia; Sydney Medical School, The University of SydneyNew South Wales, Australia.
authors.forename: John G
authors.initials: JG
authors.lastname: Harvey
authors.affiliation: Department of Paediatric Surgery, The Children's Hospital Burns Research Institute and Burns Unit, The Children's Hospital at Westmead New South Wales, Australia.
authors.forename: Erik R La
authors.initials: ER
authors.lastname: Hei
authors.affiliation: Department of Paediatric Surgery, The Children's Hospital Burns Research Institute and Burns Unit, The Children's Hospital at WestmeadNew South Wales, Australia; Sydney Medical School, The University of SydneyNew South Wales, Australia.
authors.forename: Andrew Ja
authors.initials: AJ
authors.lastname: Holland
keywords: Contact burn; partial thickness; porcine model