title: Expression of phosphate transporters in optimized cell culture models for dental cells biomineralization.
abstract: Phosphate is a key component of dental mineral composition. The physiological role of membrane proteins of dental cells is suspected to be crucial for mineralization mechanisms. Contrary to published data related to calcium, data on regulation of phosphate flux through membrane of mineralizing cells are scarce. To address this lack of data, we studied the expression of six membranous phosphate transporters in two dental cell lines: a rat odontoblastic cell line (M2H4) and a mouse ameloblastic cell line (ALC) for which we optimized the mineralizing culture conditions.
authors.forename: Laure
authors.initials: L
authors.lastname: Merametdjian
authors.forename: Amandine
authors.initials: A
authors.lastname: David
authors.forename: Nina
authors.initials: N
authors.lastname: Bon
authors.forename: Greig
authors.initials: G
authors.lastname: Couasnay
authors.forename: Jérôme
authors.initials: J
authors.lastname: Guicheux
authors.forename: Céline
authors.initials: C
authors.lastname: Gaucher
authors.forename: Sarah
authors.initials: S
authors.lastname: Beck-Cormier
authors.affiliation: INSERM UMRS_791, University of Nantes. laurent.beck@inserm.fr.
authors.forename: Laurent
authors.initials: L
authors.lastname: Beck
mesh_terms: D000565:Ameloblasts / Q000166:cytology; D000818:Animals; D002460:Cell Line; D051379:Mice; D009804:Odontoblasts / Q000166:cytology; D028061:Phosphate Transport Proteins / Q000096:biosynthesis*; D051381:Rats; D014070:Tooth / Q000378:metabolism*; D014074:Tooth Calcification / Q000502:physiology*
chemical_list: D028061:Phosphate Transport Proteins