title: Isotonic saline in children with perennial allergic rhinitis.
abstract: Children with HDM allergy suffer from perennial allergic rhinitis (PAR). The present pilot study evaluated nasal lavage with isotonic saline (0.9%) in 25 children (mean age 8.9 years; 13 males) with HDM-dependent PAR, assessing: nasal symptoms severity and parental perception of rhinitis control, sleep, and school performance. Nasal symptoms, rated by total symptom score, parental perception of PER control, sleep quality, and school performance, measured by visual analogue scale, were significantly improved by nasal lavage (p < 0.001) after treatment. The effects tended to persist also during the follow-up. In conclusion, the present pilot study provides the first evidence that nasal lavage with isotonic saline relieved the nasal symptoms of children with PAR and improved the parental perception of the disease.
authors.affiliation: Department of Pediatrics, A.O. Fatebenefratelli, Milan, Italy.
authors.forename: S
authors.initials: S
authors.lastname: Barberi
authors.affiliation: Department of Pediatrics, San Paolo Hospital, University of Milan, Italy.
authors.forename: E
authors.initials: E
authors.lastname: D Auria
authors.affiliation: Department of Pediatrics, A.O. Fatebenefratelli, Milan, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Bernardo
authors.affiliation: Department of Pediatrics, A.O. Fatebenefratelli, Milan, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Pinto
authors.affiliation: Department of Pediatrics, San Paolo Hospital, University of Milan, Italy.
authors.forename: B
authors.initials: B
authors.lastname: Pietra
authors.affiliation: Department of Medicine, IRCCS-AOU San Martino, Genoa, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Ciprandi
mesh_terms: D000818:Animals; D002648:Child; D005260:Female; D006801:Humans; D007552:Isotonic Solutions; D008297:Male; D010865:Pilot Projects; D039981:Pyroglyphidae / Q000276:immunology; D012221:Rhinitis, Allergic, Perennial / Q000188:drug therapy*; D012965:Sodium Chloride / Q000627:therapeutic use*
chemical_list: D007552:Isotonic Solutions; D012965:Sodium Chloride