title: Does the source migration pathway of HBCDs to household dust influence their bio-accessibility?
abstract: A study was conducted to assess the human bioaccessibility of dust contaminated with hexabromocyclododecane (HBCD) via two migration pathways a) volatilisation with subsequent partitioning to dust particles, and b) abrasion of treated textile fibres directly to the dust. This was achieved using previously developed experimental chamber designs to generate dust samples contaminated with HBCDs emitted from a HBCD treated textile curtain. The generated dust samples were exposed to an in vitro colon extended physiologically based extraction test (CE-PBET). The bioaccessibility of the HBCDs which were incorporated within dust as a result of volatilisation from the curtain material with subsequent partitioning to dust was higher than in dusts contaminated with HBCDs via abrasion of the curtain (35% and 15% respectively). We propose this occurs due to a stronger binding of HBCDs to treated fabric fibres than that experienced following volatilisation and sorption of HBCDs to dust particles.
authors.affiliation: Soil Research Centre, University of Reading, Reading RG6 6AH, UK.
authors.forename: Sonia
authors.initials: S
authors.lastname: García-Alcega
authors.affiliation: School of Geography Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
authors.forename: Cassie
authors.initials: C
authors.lastname: Rauert
authors.affiliation: School of Geography Earth and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, UK.
authors.forename: Stuart
authors.initials: S
authors.lastname: Harrad
authors.affiliation: Soil Research Centre, University of Reading, Reading RG6 6AH, UK. Electronic address: c.d.collins@reading.ac.uk.
authors.forename: Chris D
authors.initials: CD
authors.lastname: Collins
mesh_terms: D000393:Air Pollutants / Q000378:metabolism*; D016902:Air Pollution, Indoor / Q000032:analysis*; D001682:Biological Availability; D004391:Dust / Q000032:analysis*; D004781:Environmental Exposure; D004784:Environmental Monitoring; D005411:Flame Retardants / Q000378:metabolism; D006801:Humans; D006842:Hydrocarbons, Brominated / Q000378:metabolism*
chemical_list: D000393:Air Pollutants; D004391:Dust; D005411:Flame Retardants; D006842:Hydrocarbons, Brominated; C089796:hexabromocyclododecane
keywords: Abrasion; Flame retardants; In vitro digestion model; Indoor environment; Oral exposure; Volatilisation