title: Usefulness of Microvascular Ultrasonography in Differentiating Metastatic Lymphadenopathy from Tuberculous Lymphadenitis.
abstract: This study was undertaken to evaluate the usefulness of vascular pattern analysis on microvascular ultrasonography in distinguishing metastatic lymphadenopathy from tuberculous lymphadenitis, compared with conventional power Doppler ultrasonography, and to evaluate inter-observer agreement for microvascular ultrasonography. Thirty-four patients with metastatic lymphadenopathy and 27 patients with tuberculous lymphadenitis were included. The level of inter-observer agreement was excellent or good for all aspects of vascular pattern analysis on both ultrasonographic examinations. Vascular distribution, internal vascularity and internal vascular features of lymph nodes on microvascular ultrasonography differed significantly different (p ≤ 0.002) between metastatic lymphadenopathy and tuberculous lymphadenitis. A central vascular pattern with displacement was prevalent in metastasis, and an avascular pattern was more frequent in tuberculosis. Internal vascularity of metastasis was higher than that of tuberculosis. Vascular patterns on power Doppler ultrasonography did not differ significantly. Vascular pattern analysis using microvascular ultrasonography can be helpful in differentiating metastatic lymphadenopathy from tuberculous lymphadenitis with good inter-observer agreement.
authors.affiliation: Department of Radiology, Korea University Guro Hospital, College of Medicine, Seoul, Korea.
authors.forename: Inseon
authors.initials: I
authors.lastname: Ryoo
authors.affiliation: Department of Radiology, Korea University Guro Hospital, College of Medicine, Seoul, Korea. Electronic address: sangil.suh@gmail.com.
authors.forename: Sangil
authors.initials: S
authors.lastname: Suh
authors.affiliation: Department of Radiology, Korea University Anam Hospital, College of Medicine, Seoul, Korea.
authors.forename: Sung-Hye
authors.initials: SH
authors.lastname: You
authors.affiliation: Department of Radiology, Korea University Guro Hospital, College of Medicine, Seoul, Korea.
authors.forename: Hae Young
authors.initials: HY
authors.lastname: Seol
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D008198:Lymph Nodes / Q000000981:diagnostic imaging; D000072281:Lymphadenopathy / Q000000981:diagnostic imaging*; D008297:Male; D055806:Microvessels / Q000000981:diagnostic imaging*; D008875:Middle Aged; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014388:Tuberculosis, Lymph Node / Q000000981:diagnostic imaging*; D014463:Ultrasonography / Q000379:methods*; D018615:Ultrasonography, Doppler, Color / Q000379:methods
keywords: Cervical lymph node; Metastasis; Microvascular ultrasonography; Power Doppler ultrasonography; Superb Microvascular Imaging; Tuberculosis; Vascular pattern