title: Digital Glissonectomy: A Safe Perihepatic Peritonectomy.
abstract: Complete cytoreductive surgery (CRS), combining organ resection and peritonectomy, is the only treatment that could offer cure for patients with peritoneal carcinomatosis. Initially, when the Glisson's capsule was involved without deep liver parenchyma invasion, either electroevaporation or Glisson's capsule resection was proposed. The objective of this study is to present and evaluate the safety of this standardized digital glissonectomy.
  
  
  
  Since 2009, the peritonectomy of the Glisson's capsule, or digital glissonectomy, has been standardized at our institution.
  
  
  
  Among 655 patients who underwent a complete CRS between 2009 and 2014, 91 (14 %) glissonectomies were performed. Pseudomyxoma peritonei was the primary indication, and a glissonectomy was more frequently performed for patients with high peritoneal cancer index. The morbidity and mortality of CRS were not increased after glissonectomy (p = 0.069 and 0.949, respectively).
  
  
  
  Digital glissonectomy is feasible and safe, when proposed for superficial deposits on Glisson's capsule.
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France. guillaume.passot@chu-lyon.fr.|EMR 37 38, Lyon 1 University, Oullins, Lyon, France. guillaume.passot@chu-lyon.fr.
authors.forename: Guillaume
authors.initials: G
authors.lastname: Passot
authors.affiliation: Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA.
authors.forename: Bradford J
authors.initials: BJ
authors.lastname: Kim
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France.|EMR 37 38, Lyon 1 University, Oullins, Lyon, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Vaudoyer
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France.|EMR 37 38, Lyon 1 University, Oullins, Lyon, France.
authors.forename: Vahan
authors.initials: V
authors.lastname: Kepenekian
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Bonnefoy
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France.|EMR 37 38, Lyon 1 University, Oullins, Lyon, France.
authors.forename: Naoual
authors.initials: N
authors.lastname: Bakrin
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France.|EMR 37 38, Lyon 1 University, Oullins, Lyon, France.
authors.forename: Eddy
authors.initials: E
authors.lastname: Cotte
authors.affiliation: Department of Surgical Oncology, Hospices Civils de Lyon, CH Lyon Sud, Lyon, France.|EMR 37 38, Lyon 1 University, Oullins, Lyon, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Glehen
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D002166:Camptothecin / Q000008:administration & dosage / Q000031:analogs & derivatives; D002945:Cisplatin / Q000008:administration & dosage; D065426:Cytoreduction Surgical Procedures / Q000379:methods; D005260:Female; D006801:Humans; D006979:Hyperthermia, Induced; D000077146:Irinotecan; D008099:Liver / Q000601:surgery*; D008113:Liver Neoplasms / Q000556:secondary / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D016685:Mitomycin / Q000008:administration & dosage; D009944:Organoplatinum Compounds / Q000008:administration & dosage; D000077150:Oxaliplatin; D010534:Peritoneal Neoplasms / Q000556:secondary / Q000628:therapy*; D010537:Peritoneum / Q000601:surgery*; D011553:Pseudomyxoma Peritonei / Q000628:therapy*; D055815:Young Adult
chemical_list: D009944:Organoplatinum Compounds; D000077150:Oxaliplatin; D016685:Mitomycin; D000077146:Irinotecan; D002945:Cisplatin; D002166:Camptothecin