title: [Temporal and spacial expression of LIM mineralization protein 1 during rat pulp injury and reparation].
abstract: OBJECTIVE
  To investigate the expression and localization of LIM mineralization protein 1(LMP-1) during rat pulp injury and reparation.
  
  
  METHODS
  Dental pulp injury models were established in maxillary first molars on one side of 12 Wistar rats, the isonym healthy teeth on the opposite side were used as the controls. Immunohistochemistry technique was used to observe the expression of LMP-1 at 1, 3 and 7 day after pulp injury. The results of staining were analyzed by Image-Pro Plus 6.0 and SPSS 17.0 software package.
  
  
  RESULTS
  LMP-1 was not detected in normal rat dental pulp. Positive staining of LMP-1 was found in odontoblasts and some dental pulp cells at 1 day after pulp injury. The expression of LMP-1 was converged at cell proliferation zone under the injury site at 3 and 7 day after injury.
  
  
  CONCLUSIONS
  LMP-1 might play a role in the dental pulp cell proliferation and differentiation and reparative dentin formation during pulp injury and reparation.
authors.affiliation: Affiliated Stomatology Hospital, Wenzhou Medical University. Wenzhou 325027, Zhejiang Province, China. E-mail:fangpingjuan@wzmc.edu.cn.
authors.forename: Ping-juan
authors.initials: PJ
authors.lastname: Fang
authors.affiliation: Affiliated Stomatology Hospital, Wenzhou Medical University. Wenzhou 325027, Zhejiang Province, China.
authors.forename: Yi-huai
authors.initials: YH
authors.lastname: Pan
authors.affiliation: Affiliated Stomatology Hospital, Wenzhou Medical University. Wenzhou 325027, Zhejiang Province, China.
authors.forename: Ren-yi
authors.initials: RY
authors.lastname: Sun
authors.affiliation: Affiliated Stomatology Hospital, Wenzhou Medical University. Wenzhou 325027, Zhejiang Province, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Affiliated Stomatology Hospital, Wenzhou Medical University. Wenzhou 325027, Zhejiang Province, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Sun
mesh_terms: D048868:Adaptor Proteins, Signal Transducing / Q000378:metabolism*; D000818:Animals; D002454:Cell Differentiation; D003598:Cytoskeletal Proteins / Q000378:metabolism*; D003782:Dental Pulp / Q000378:metabolism*; D007150:Immunohistochemistry; D060588:LIM Domain Proteins / Q000378:metabolism*; D008963:Molar; D009804:Odontoblasts; D051381:Rats; D017208:Rats, Wistar
chemical_list: D048868:Adaptor Proteins, Signal Transducing; D003598:Cytoskeletal Proteins; D060588:LIM Domain Proteins; C484380:PDLIM7 protein, human