title: Methods for Doping Detection.
abstract: Over the past few years, the World Anti-Doping Agency (WADA) has focused its efforts on detecting not only small prohibited molecules, but also larger endogenous molecules such as hormones, in the view of implementing an endocrinological module in the Athlete Biological Passport (ABP). In this chapter, the detection of two major types of hormones used for doping, growth hormone (GH) and endogenous anabolic androgenic steroids (EAASs), will be discussed: a brief historical background followed by a description of state-of-the-art methods applied by accredited anti-doping laboratories will be provided and then current research trends outlined. In addition, microRNAs (miRNAs) will also be presented as a new class of biomarkers for doping detection.
authors.forename: Federico
authors.initials: F
authors.lastname: Ponzetto
authors.forename: Sylvain
authors.initials: S
authors.lastname: Giraud
authors.forename: Nicolas
authors.initials: N
authors.lastname: Leuenberger
authors.forename: Julien
authors.initials: J
authors.lastname: Boccard
authors.forename: Raul
authors.initials: R
authors.lastname: Nicoli
authors.forename: Norbert
authors.initials: N
authors.lastname: Baume
authors.forename: Serge
authors.initials: S
authors.lastname: Rudaz
authors.forename: Martial
authors.initials: M
authors.lastname: Saugy
mesh_terms: D015415:Biomarkers / Q000378:metabolism*; D004300:Doping in Sports; D013006:Growth Hormone / Q000032:analysis*; D006801:Humans; D045165:Testosterone Congeners / Q000032:analysis*
chemical_list: D015415:Biomarkers; D045165:Testosterone Congeners; D013006:Growth Hormone