title: Enantioselective carbenoid insertion into C(sp(3))-H bonds.
abstract: The enantioselective carbenoid insertion into C(sp(3))-H bonds is an important tool for the synthesis of complex molecules due to the high control of enantioselectivity in the formation of stereogenic centers. This paper presents a brief review of the early issues, related mechanistic studies and recent applications on this chemistry area.
authors.affiliation: Grupo de Tecnologia em Síntese Orgânica, Instituto de Química, Universidade de Brasília, Campus Universitário Darcy Ribeiro, 4478, CEP 70904-970, Asa Norte, Brasília-DF, Brasil.
authors.forename: J V
authors.initials: JV
authors.lastname: Santiago
authors.affiliation: Grupo de Tecnologia em Síntese Orgânica, Instituto de Química, Universidade de Brasília, Campus Universitário Darcy Ribeiro, 4478, CEP 70904-970, Asa Norte, Brasília-DF, Brasil.
authors.forename: A H L
authors.initials: AH
authors.lastname: Machado
keywords: C–H activation; chiral catalysis; diazo compounds; total synthesis