title: Measuring Health-Related Quality of Life of Adults With Down Syndrome.
abstract: This study examined self- and caregiver-reported health-related quality of life (HRQOL) of 60 adults with Down syndrome (DS) using the QualityMetric Short Form-12 version 2 (SF-12v2). All HRQOL scores exceeded means and fell within one standard deviation of the SF-12v2 normative sample. Similarities between eight self- and caregiver-reported HRQOL scales were found with the exception of role physical scores (impact of health problems on typical accomplishments), which were lower when obtained by caregiver-report. A positive association was found between self- and caregiver-reported physical functioning scores (impact of health problems on physical activity). The SF-12v2 had high construct validity in this study. These findings support the feasibility of measuring HRQOL of adults with DS using self-report rather than reliance on caregiver-report.
authors.affiliation: Rebecca Jermyn Graves, University of South Alabama; J. Carolyn Graff, Donna K. Hathaway, Jim Y. Wan, and Mona Newsome Wicks, University of Tennessee Health Science Center; Anna J. Esbensen, Cincinnati Children's Hospital Medical Center.
authors.forename: Rebecca Jermyn
authors.initials: RJ
authors.lastname: Graves
authors.affiliation: Rebecca Jermyn Graves, University of South Alabama; J. Carolyn Graff, Donna K. Hathaway, Jim Y. Wan, and Mona Newsome Wicks, University of Tennessee Health Science Center; Anna J. Esbensen, Cincinnati Children's Hospital Medical Center.
authors.forename: J Carolyn
authors.initials: JC
authors.lastname: Graff
authors.affiliation: Rebecca Jermyn Graves, University of South Alabama; J. Carolyn Graff, Donna K. Hathaway, Jim Y. Wan, and Mona Newsome Wicks, University of Tennessee Health Science Center; Anna J. Esbensen, Cincinnati Children's Hospital Medical Center.
authors.forename: Anna J
authors.initials: AJ
authors.lastname: Esbensen
authors.affiliation: Rebecca Jermyn Graves, University of South Alabama; J. Carolyn Graff, Donna K. Hathaway, Jim Y. Wan, and Mona Newsome Wicks, University of Tennessee Health Science Center; Anna J. Esbensen, Cincinnati Children's Hospital Medical Center.
authors.forename: Donna K
authors.initials: DK
authors.lastname: Hathaway
authors.affiliation: Rebecca Jermyn Graves, University of South Alabama; J. Carolyn Graff, Donna K. Hathaway, Jim Y. Wan, and Mona Newsome Wicks, University of Tennessee Health Science Center; Anna J. Esbensen, Cincinnati Children's Hospital Medical Center.
authors.forename: Jim Y
authors.initials: JY
authors.lastname: Wan
authors.affiliation: Rebecca Jermyn Graves, University of South Alabama; J. Carolyn Graff, Donna K. Hathaway, Jim Y. Wan, and Mona Newsome Wicks, University of Tennessee Health Science Center; Anna J. Esbensen, Cincinnati Children's Hospital Medical Center.
authors.forename: Mona Newsome
authors.initials: MN
authors.lastname: Wicks
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D000328:Adult; D000368:Aged; D017028:Caregivers; D004314:Down Syndrome / Q000503:physiopathology* / Q000523:psychology; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D019727:Proxy; D011788:Quality of Life; D015203:Reproducibility of Results; D057566:Self Report; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Down syndrome; adults; health-related quality of life; self-report