title: Polydopamine Hollow Nanoparticle Functionalized with N-diazeniumdiolates as a Nitric Oxide Delivery Carrier for Antibacterial Therapy.
abstract: A biocompatible nitric oxide (NO) delivery nanoplatform, whose structure is a hollow nanoparticle composed of polydopamine backbone and diazeniumdiolates functional groups, is developed for antibacterial therapy. This platform liberates high NO quantitis and exerts the antibacterial activity with excellent biocompatibility thus being promising for treating bacterial infections.
authors.affiliation: Center for Self-Assembly and Complexity, Institute for Basic Science (IBS), Pohang, 37673, South Korea.|Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang, 37673, South Korea.
authors.forename: Dongsik
authors.initials: D
authors.lastname: Park
authors.affiliation: Center for Self-Assembly and Complexity, Institute for Basic Science (IBS), Pohang, 37673, South Korea.|Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang, 37673, South Korea.
authors.forename: Jihoon
authors.initials: J
authors.lastname: Kim
authors.affiliation: Center for Self-Assembly and Complexity, Institute for Basic Science (IBS), Pohang, 37673, South Korea.|Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang, 37673, South Korea.
authors.forename: Yeong Mi
authors.initials: YM
authors.lastname: Lee
authors.affiliation: Center for Self-Assembly and Complexity, Institute for Basic Science (IBS), Pohang, 37673, South Korea.|Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang, 37673, South Korea.
authors.forename: Junghong
authors.initials: J
authors.lastname: Park
authors.affiliation: Center for Self-Assembly and Complexity, Institute for Basic Science (IBS), Pohang, 37673, South Korea.|Department of Chemistry, Pohang University of Science and Technology (POSTECH), Pohang, 37673, South Korea.
authors.forename: Won Jong
authors.initials: WJ
authors.lastname: Kim
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D001391:Azo Compounds / Q000737:chemistry / Q000494:pharmacology; D004337:Drug Carriers / Q000737:chemistry / Q000494:pharmacology; D053758:Nanoparticles / Q000737:chemistry*; D009569:Nitric Oxide / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D001391:Azo Compounds; D004337:Drug Carriers; C452539:diazeniumdiolate; D009569:Nitric Oxide
keywords: antibacterials; biocompatibility; nitric oxide; polydopamine