title: "Assessment of effectiveness and security in high pressure postdilatation of bioresorbable vascular scaffolds during percutaneous coronary intervention. Study in a contemporary, non-selected cohort of Spanish patients".
abstract: OBJECTIVE
  To determine security and benefits of high pressure postdilatation (HPP) of bioresorbable vascular scaffolds (BVS) in percutaneous coronary intervention (PCI) of complex lesions whatever its indication is.
  
  
  BACKGROUND
  Acute scaffold disruption has been proposed as the main limitation of BVS when they are overexpanded. However, clinical implications of this disarray are not yet clear and more evidence is needed.
  
  
  METHODS
  A total of 25 BVS were deployed during PCI of 14 complex lesions after mandatory predilatation. In all cases HPP was performed with NC balloon in a 1:1 relation to the artery. After that, optical coherence tomography (OCT) analyses were performed.
  
  
  RESULTS
  Mean and maximal postdilatation pressure were 17±3.80 and 20 atmospheres (atm) respectively. Postdilatation balloon/scaffold diameter ratio was 1.01. A total of 39,590 struts were analyzed. Mean, minimal and maximal scaffold diameter were respectively: 3.09±0.34mm, 2.88±0.31mm and 3.31±0.40mm. Mean eccentricity index was 0.13±0.05. ISA percentage was 1.42% with a total of 564 malapposed struts. 89 struts were identified as disrupted, which represents a percentage of disrupted struts of 0.22%. At 30days, none of our patients died, suffered from stroke, stent thrombosis or needed target lesion revascularization (TLR).
  
  
  CONCLUSIONS
  NC balloon HPP of BVS at more than 17atm (up to 20atm) is safe during PCI and allows to achieve better angiographic and clinical results.
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain. Electronic address: albaabellas@gmail.com.
authors.forename: Rosa A
authors.initials: RA
authors.lastname: Abellas-Sequeiros
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Raymundo
authors.initials: R
authors.lastname: Ocaranza-Sanchez
authors.affiliation: Interventional Cardiology Unit, Hospital de Braga, 4710 Braga, Portugal.
authors.forename: Carlos
authors.initials: C
authors.lastname: Galvão Braga
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Sergio
authors.initials: S
authors.lastname: Raposeiras-Roubin
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Diego
authors.initials: D
authors.lastname: Lopez-Otero
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Belen
authors.initials: B
authors.lastname: Cid-Alvarez
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Souto-Castro
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Ramiro
authors.initials: R
authors.lastname: Trillo-Nouche
authors.affiliation: Interventional Cardiology Unit, Universitary Clinical Hospital of Santiago de Compostela, 15706, Spain.
authors.forename: Jose R
authors.initials: JR
authors.lastname: Gonzalez-Juanatey
mesh_terms: D020341:Absorbable Implants / Q000592:standards*; D000368:Aged; D015331:Cohort Studies; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000601:surgery*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D062645:Percutaneous Coronary Intervention / Q000379:methods / Q000592:standards*; D011312:Pressure; D011446:Prospective Studies; D013030:Spain / Q000453:epidemiology; D054457:Tissue Scaffolds / Q000592:standards*; D041623:Tomography, Optical Coherence / Q000379:methods / Q000592:standards*; D016896:Treatment Outcome; D014664:Vasodilation / Q000502:physiology*
keywords: Bioresorbable vascular scaffolds; OCT; PCI; STEMI