title: Strategies to Mitigate a Mycobacterium marinum Outbreak in a Zebrafish Research Facility.
abstract: In 2011, the zebrafish research facility at the University of Oregon experienced an outbreak of Mycobacterium marinum that affected both research fish and facility staff. A thorough review of risks to personnel, the zebrafish veterinary care program, and zebrafish husbandry procedures at the research facility followed. In the years since 2011, changes have been implemented throughout the research facility to protect the personnel, the fish colony, and ultimately the continued success of the zebrafish model research program. In this study, we present the history of the outbreak, the changes we implemented, and recommendations to mitigate pathogen outbreaks in zebrafish research facilities.
authors.affiliation: 1 Aquatic Animal Care Services, University of Oregon , Eugene, Oregon.
authors.forename: Timothy
authors.initials: T
authors.lastname: Mason
authors.affiliation: 1 Aquatic Animal Care Services, University of Oregon , Eugene, Oregon.
authors.forename: Kathy
authors.initials: K
authors.lastname: Snell
authors.affiliation: 2 Institute of Molecular Biology, University of Oregon , Eugene, Oregon.
authors.forename: Erika
authors.initials: E
authors.lastname: Mittge
authors.affiliation: 3 Institute of Neuroscience, University of Oregon , Eugene, Oregon.
authors.forename: Ellie
authors.initials: E
authors.lastname: Melancon
authors.affiliation: 1 Aquatic Animal Care Services, University of Oregon , Eugene, Oregon.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Montgomery
authors.affiliation: 1 Aquatic Animal Care Services, University of Oregon , Eugene, Oregon.
authors.forename: Marcie
authors.initials: M
authors.lastname: McFadden
authors.affiliation: 1 Aquatic Animal Care Services, University of Oregon , Eugene, Oregon.
authors.forename: Javier
authors.initials: J
authors.lastname: Camoriano
authors.affiliation: 4 Department of Microbiology and Biomedical Sciences, Oregon State University , Corvallis, Oregon.
authors.forename: Michael L
authors.initials: ML
authors.lastname: Kent
authors.affiliation: 5 SUNY-ESF, State University of New York College of Environmental Science and Forestry , Syracuse, New York.
authors.forename: Christopher M
authors.initials: CM
authors.lastname: Whipps
authors.affiliation: 3 Institute of Neuroscience, University of Oregon , Eugene, Oregon.
authors.forename: Judy
authors.initials: J
authors.lastname: Peirce
mesh_terms: D000822:Animal Husbandry; D000818:Animals; D017756:Aquaculture; D004196:Disease Outbreaks / Q000517:prevention & control / Q000662:veterinary*; D005393:Fish Diseases / Q000453:epidemiology* / Q000382:microbiology / Q000517:prevention & control*; D009165:Mycobacterium Infections, Nontuberculous / Q000453:epidemiology / Q000382:microbiology / Q000517:prevention & control / Q000662:veterinary*; D019910:Mycobacterium marinum / Q000502:physiology; D009922:Oregon / Q000453:epidemiology; D015027:Zebrafish