title: [Visceral leishmaniasis in adults: about twelve cases].
abstract: Visceral leishmaniasis is a vector-borne disease essentially associated with Leishmania infantum infection in the Mediterranean basin. Although rare in adults, its prevalence has recently increased even among immunocompetent individuals. The aim of our study is to reveal the epidemiological features of visceral leishmaniasis in adults and the importance of biological diagnostic in the identification of this disease. Our study spanned six years from January 2009 to January 2014 and data were collected from twelve patients hospitalized at University Hospital Hassan II, Fez. Alteration of general state and splenomegaly dominated the clinical picture. Biologically, anemia was almost constant. Diagnosis was confirmed by parasite identification at the level of bone marrow. The response to treatment was favorable for all our patients. Thus, visceral leishmaniasis recrudescence in adults and its nonspecific clinical picture must lead the clinicians to suspect it when fever accompanying splenomegaly occurs, thus enabling early diagnosis and therapeutic management.
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Imane
authors.initials: I
authors.lastname: Benbella
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Fatima
authors.initials: F
authors.lastname: Aich
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Majdouline
authors.initials: M
authors.lastname: Elkhiyat
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Hanane
authors.initials: H
authors.lastname: Khalki
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Assya
authors.initials: A
authors.lastname: Khermach
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Imane
authors.initials: I
authors.lastname: Bergui
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Imane
authors.initials: I
authors.lastname: Tlemçani
authors.affiliation: Service d'Hématologie, Laboratoire des Analyses Médicales, Centre Hospitalier Universitaire de Fès, Maroc.
authors.forename: Moncef Amrani
authors.initials: MA
authors.lastname: Hassani
mesh_terms: D000293:Adolescent; D000328:Adult; D000740:Anemia / Q000469:parasitology; D001853:Bone Marrow / Q000469:parasitology*; D005260:Female; D005334:Fever / Q000469:parasitology; D006785:Hospitals, University; D006801:Humans; D018314:Leishmania infantum / Q000302:isolation & purification*; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D009018:Morocco / Q000453:epidemiology; D012189:Retrospective Studies; D013163:Splenomegaly / Q000469:parasitology*; D055815:Young Adult
keywords: Visceral leishmaniasis; adult; immunocompetent