title: Can generic knee joint models improve the measurement of osteoarthritic knee kinematics during squatting activity?
abstract: Knee joint kinematics derived from multi-body optimisation (MBO) still requires evaluation. The objective of this study was to corroborate model-derived kinematics of osteoarthritic knees obtained using four generic knee joint models used in musculoskeletal modelling - spherical, hinge, degree-of-freedom coupling curves and parallel mechanism - against reference knee kinematics measured by stereo-radiography. Root mean square errors ranged from 0.7° to 23.4° for knee rotations and from 0.6 to 9.0 mm for knee displacements. Model-derived knee kinematics computed from generic knee joint models was inaccurate. Future developments and experiments should improve the reliability of osteoarthritic knee models in MBO and musculoskeletal modelling.
authors.affiliation: a Département de génie de la production automatisée , École de technologie supérieure (ÉTS) , Montréal , Canada.|b Laboratoire de recherche en imagerie et orthopédie (LIO) , Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM) , Montréal , Canada.
authors.forename: Julien
authors.initials: J
authors.lastname: Clément
authors.affiliation: c Université de Lyon , Lyon , France.|d Université Claude Bernard Lyon 1 , Villeurbanne , France.|e Laboratoire de Biomécanique et Mécanique des Chocs , IFSTTAR, UMR_T9406 , Bron , France.
authors.forename: Raphaël
authors.initials: R
authors.lastname: Dumas
authors.affiliation: a Département de génie de la production automatisée , École de technologie supérieure (ÉTS) , Montréal , Canada.|b Laboratoire de recherche en imagerie et orthopédie (LIO) , Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM) , Montréal , Canada.
authors.forename: Nicola
authors.initials: N
authors.lastname: Hagemeister
authors.affiliation: a Département de génie de la production automatisée , École de technologie supérieure (ÉTS) , Montréal , Canada.|b Laboratoire de recherche en imagerie et orthopédie (LIO) , Centre de recherche du Centre hospitalier de l'Université de Montréal (CRCHUM) , Montréal , Canada.
authors.forename: Jaques A
authors.initials: JA
authors.lastname: de Guise
mesh_terms: D000368:Aged; D001696:Biomechanical Phenomena; D015992:Body Mass Index; D005260:Female; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007719:Knee Joint / Q000033:anatomy & histology*; D008297:Male; D008875:Middle Aged; D008954:Models, Biological; D010003:Osteoarthritis / Q000175:diagnosis*; D011187:Posture / Q000502:physiology*; D016059:Range of Motion, Articular; D015203:Reproducibility of Results
keywords: Knee osteoarthritis; multi-body optimisation; soft tissue artefact; stereo-radiography; validation