title: [The Reliability of Measurement Methods for Medical Examinations and Health Screening].
abstract: Clinical laboratory data used in medical examinations and health screening need to have a guaranteed analytical reliability. To ensure the reliability of measurement data, each constituent is required to be compatible with its traceability chain, and any constituent whose traceability chain has yet to be established is required to be appropriately harmonized in the current measurement system. The inter-laboratory reproducibility of standardized measurement values obtained from the external quality assessments conducted by the Japan Medical Association and Japanese Association of Medical Technologists was estimated to evaluate the analytical reliability of clinical tests in Japan. The estimated inter-laboratory reproducibility was then compared with the permissible error limits which have been reported domestically and internationally based on inter- and intra-individual biological variations of healthy subjects. The results showed that most of the measurement uncertainties were sufficiently lower than the permissible limits. This study proposes that the measurement uncertainty of the standardized measurement method has the potential to be a new assessment standard for analytical reliability.
authors.forename: Shigemi
authors.initials: S
authors.lastname: Hosogaya
mesh_terms: D019411:Clinical Laboratory Techniques / Q000379:methods* / Q000706:statistics & numerical data; D010808:Physical Examination / Q000379:methods* / Q000592:standards; D015203:Reproducibility of Results