title: Analytical Applications of Nanomaterials in Monitoring Biological and Chemical Contaminants in Food.
abstract: The detection of food pathogens is an important aspect of food safety. A range of detection systems and new analytical materials have been developed to achieve fast, sensitive, and accurate monitoring of target pathogens. In this review, we summarize the characteristics of selected nanomaterials and their applications in food, and place focus on the monitoring of biological and chemical contaminants in food. The unique optical and electrical properties of nanomaterials, such as gold nanoparticles, nanorods, quantum dots, carbon nanotubes, graphenes, nanopores, and polydiacetylene nanovesicles, are closely associated with their dimensions, which are comparable in scale to those of targeted biomolecules. Furthermore, their optical and electrical properties are highly dependent on local environments, which make them promising materials for sensor development. The specificity and selectivity of analytical nanomaterials for target contaminants can be achieved by combining them with various biological entities, such as antibodies, oligonucleotides, aptamers, membrane proteins, and biological ligands. Examples of nanomaterial-based analytical systems are presented together with their limitations and associated developmental issues.
authors.affiliation: Graduate School of Biotechnology & Department of Food Science and Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Republic of Korea.|Korea Food Research Institute, Seongnam 13539, Republic of Korea.
authors.forename: Min-Cheol
authors.initials: MC
authors.lastname: Lim
authors.affiliation: Graduate School of Biotechnology & Department of Food Science and Biotechnology, College of Life Sciences, Kyung Hee University, Yongin 17104, Republic of Korea.
authors.forename: Young-Rok
authors.initials: YR
authors.lastname: Kim
mesh_terms: D001419:Bacteria / Q000302:isolation & purification / Q000472:pathogenicity; D015374:Biosensing Techniques / Q000379:methods*; D005516:Food Microbiology / Q000379:methods*; D059022:Food Safety / Q000379:methods*; D049329:Nanostructures; D036103:Nanotechnology / Q000379:methods*
keywords: Analytical nanomaterials; biosensor; food contaminants; food safety; pathogenic bacteria