title: How to produce high specific activity tin-117m using alpha particle beam.
abstract: Tin-117m is an interesting radionuclide for both diagnosis and therapy, thanks to the gamma-ray and electron emissions, respectively, resulting from its decay to tin-117g. The high specific activity of tin-117m is required in many medical applications, and it can be obtained using a high energy alpha particle beam and a cadmium target. The experiments performed at the ARRONAX cyclotron (Nantes, France) using an alpha particle beam delivered at 67.4MeV provide a measurement of the excitation function of the Cd-nat(α,x)Sn-117m reaction and the produced contaminants. The Cd-116(α,3n)Sn-117m production cross section has been deduced from these experimental results using natural cadmium. Both production yield and specific activity as a function of the projectile energy have been calculated. These informations help to optimize the irradiation conditions to produce tin-117m with the required specific activity using α particles with a cadmium target.
authors.affiliation: SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France. Electronic address: Charlotte.Duchemin@subatech.in2p3.fr.
authors.forename: C
authors.initials: C
authors.lastname: Duchemin
authors.affiliation: SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France.
authors.forename: M
authors.initials: M
authors.lastname: Essayan
authors.affiliation: SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France.
authors.forename: A
authors.initials: A
authors.lastname: Guertin
authors.affiliation: SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France; GIP Arronax, 1 rue Aronnax, 44817 Saint-Herblain, France.
authors.forename: F
authors.initials: F
authors.lastname: Haddad
authors.affiliation: SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France; GIP Arronax, 1 rue Aronnax, 44817 Saint-Herblain, France.
authors.forename: N
authors.initials: N
authors.lastname: Michel
authors.affiliation: SUBATECH, Ecole des Mines de Nantes, Université de Nantes, CNRS/IN2P3, 44307 Nantes, France.
authors.forename: V
authors.initials: V
authors.lastname: Métivier
keywords: ARRONAX cyclotron; Cadmium target; Specific activity; Tin-117m