title: Intervendor consistency and reproducibility of left ventricular 2D global and regional strain with two different high-end ultrasound systems.
abstract: OBJECTIVE
  We aimed to assess intervendor agreement of global (GLS) and regional longitudinal strain by vendor-specific software after EACVI/ASE Industry Task Force Standardization Initiatives for Deformation Imaging.
  
  
  RESULTS
  Fifty-five patients underwent prospective dataset acquisitions on the same day by the same operator using two commercially available cardiac ultrasound systems (GE Vivid E9 and Philips iE33). GLS and regional peak longitudinal strain were analyzed offline using corresponding vendor-specific software (EchoPAC BT13 and QLAB version 10.3). Absolute mean GLS measurements were similar between the two vendors (GE -17.5 ± 5.2% vs. Philips -18.9 ± 5.1%, P = 0.15). There was excellent intervendor correlation of GLS by the same observer [r = 0.94, P < 0.0001; bias -1.3%, 95% CI limits of agreement (LOA) -4.8 to 2.2%). Intervendor comparison for regional longitudinal strain by coronary artery territories distribution were: LAD: r = 0.85, P < 0.0001; bias 0.5%, LOA -5.3 to 6.4%; RCA: r = 0.88, P < 0.0001; bias -2.4%, LOA -8.6 to 3.7%; LCX: r = 0.76, P < 0.0001; bias -5.3%, LOA -10.6 to 2.0%. Intervendor comparison for regional longitudinal strain by LV levels were: basal: r = 0.86, P < 0.0001; bias -3.6%, LOA -9.9 to 2.0%; mid: r = 0.90, P < 0.0001; bias -2.6%, LOA -7.8 to 2.6%; apical: r = 0.74; P < 0.0001; bias -1.3%, LOA -9.4 to 6.8%.
  
  
  CONCLUSIONS
  Intervendor agreement in GLS and regional strain measurements have significantly improved after the EACVI/ASE Task Force Strain Standardization Initiatives. However, significant wide LOA still exist, especially for regional strain measurements, which remains relevant when considering vendor-specific software for serial measurements.
authors.affiliation: School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.
authors.forename: Kenji
authors.initials: K
authors.lastname: Shiino
authors.affiliation: School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.
authors.forename: Akira
authors.initials: A
authors.lastname: Yamada
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Matthew
authors.initials: M
authors.lastname: Ischenko
authors.affiliation: Aurora Cardiovascular Services, Aurora Sinai/Aurora St. Luke's Medical Centers, Milwaukee, WI, USA.
authors.forename: Bijoy K
authors.initials: BK
authors.lastname: Khandheria
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Mahala
authors.initials: M
authors.lastname: Hudaverdi
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Vicki
authors.initials: V
authors.lastname: Speranza
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Mary
authors.initials: M
authors.lastname: Harten
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Anthony
authors.initials: A
authors.lastname: Benjamin
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.|University of Washington, Seattle, WA, USA.
authors.forename: Christian R
authors.initials: CR
authors.lastname: Hamilton-Craig
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: David G
authors.initials: DG
authors.lastname: Platts
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Darryl J
authors.initials: DJ
authors.lastname: Burstow
authors.affiliation: Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Gregory M
authors.initials: GM
authors.lastname: Scalia
authors.affiliation: School of Medicine and Menzies Health Institute Queensland, Griffith University, Gold Coast, Australia.|Department of Cardiology, The Prince Charles Hospital, University of Queensland, Rode Road, Chermside, Brisbane, QLD 4032, Australia.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Chan
mesh_terms: D000368:Aged; D016208:Databases, Factual; D004452:Echocardiography / Q000295:instrumentation* / Q000379:methods; D004867:Equipment Design; D004869:Equipment Safety; D005260:Female; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D011446:Prospective Studies; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging* / Q000503:physiopathology
keywords: speckle-tracking echocardiography; strain