title: Rethinking cognition and behavior in the new classification for childhood epilepsy: Examples from frontal lobe and temporal lobe epilepsies.
abstract: The new approach to classification of the epilepsies emphasizes the role of dysfunction in networks in defining types of epilepsies. This paper reviews the structural and neuropsychological deficits in two types of childhood epilepsy: frontal lobe and temporal lobe epilepsy. The evidence for and against a pattern of specificity of deficits in executive function and memory associated with these two types of epilepsies is presented. The evidence varies with the methodologies used in the studies, but direct comparison of the two types of epilepsies does not suggest a clear-cut mapping of function onto structure. These findings are discussed in light of the concept of network dysfunction. The evidence supports the conceptualization of epilepsy as a network disease. Implications for future work in the neuropsychology of pediatric epilepsy are suggested. This article is part of a Special Issue entitled "The new approach to classification: Rethinking cognition and behavior in epilepsy".
authors.affiliation: University of Toronto Mississauga, 3359 Mississauga Road, Mississauga, ON L5L 1C6, Canada; The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada. Electronic address: marylou.smith@utoronto.ca.
authors.forename: Mary Lou
authors.initials: ML
authors.lastname: Smith
mesh_terms: D002648:Child; D002653:Child Behavior Disorders / Q000145:classification* / Q000000981:diagnostic imaging / Q000453:epidemiology; D003071:Cognition; D003072:Cognition Disorders / Q000145:classification* / Q000175:diagnosis / Q000453:epidemiology; D017034:Epilepsy, Frontal Lobe / Q000145:classification* / Q000175:diagnosis / Q000453:epidemiology; D004833:Epilepsy, Temporal Lobe / Q000145:classification* / Q000175:diagnosis / Q000453:epidemiology; D056344:Executive Function; D006801:Humans; D008568:Memory; D059906:Neuroimaging / Q000145:classification / Q000379:methods; D009483:Neuropsychological Tests; D013850:Thinking
keywords: Children; Executive function; Memory; Networks; Neuropsychology