title: Comparison of two power densities on the healing of palatal wounds after connective tissue graft removal: randomized clinical trial.
abstract: Connective tissue graft (CTG), which is considered to be among the best techniques for treating gingival recession, has presented stable long-term results. However, this technique causes morbidity and discomfort in the palatine region due to graft removal at that site. A previous study reports that photobiomodulation (PBM) using a dosage of 15 J/cm(2) may improve wound healing and the patient's postoperative comfort. However, no other studies in the literature provide the best application dosage or comparisons between protocols for this purpose. The aim of this study is to compare two power densities of PBM on the wound-healing process of the donor palatine area after CTG removal. In this study, 51 patients presenting buccal gingival recession were randomized into one of the following groups: group 1: CTG procedure for root coverage and PBM application at the donor site using a 60 J/cm(2) dose; group 2: CTG and PBM application using a 30 J/cm(2) dose; or group 3: CTG and sham application. The evaluated parameters were the wound remaining area (WRA), scar and tissue colorimetry (TC), tissue thickness (TT), and postoperative discomfort (D), evaluated at baseline and 7, 14, 45, 60, and 90 days after surgery. Group 1 presented statistically significant smaller wounds at day 7 (p > 0.05). None of the patients presented scars at the operated area, and all of the patients reported mild discomfort, with low consumption of analgesic pills. We concluded that the protocol of 60 J/cm(2) provided faster wound healing 7 days after removing the connective tissue graft for root coverage.
  
  
  BACKGROUND
  ClinicalTrial.org (NCT02580357) https://clinicaltrials.gov/ct2/show/NCT02580357 .
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Felipe Lucas
authors.initials: FL
authors.lastname: da Silva Neves
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Camila Augusto
authors.initials: CA
authors.lastname: Silveira
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Stephanie Botti Fernandes
authors.initials: SB
authors.lastname: Dias
authors.affiliation: Department of Orthodontics, College of Dentistry, University of Araras, Araras, Brazil.
authors.forename: Milton
authors.initials: M
authors.lastname: Santamaria Júnior
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Andrea Carvalho
authors.initials: AC
authors.lastname: de Marco
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Warley David
authors.initials: WD
authors.lastname: Kerbauy
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Antonio Braulino
authors.initials: AB
authors.lastname: de Melo Filho
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil.
authors.forename: Maria Aparecida Neves
authors.initials: MA
authors.lastname: Jardini
authors.affiliation: Department of Diagnosis and Surgery, College of Dentistry-FOSJC, UNESP-Univ Estadual Paulista, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil. mauro.santamaria@fosjc.unesp.br.|Division of Periodontics, College of Dentistry-FOSJC, UNESP-State University of São Paulo, Av. Eng. Francisco José Longo, 777, São José dos Campos, SP, 12245-000, Brazil. mauro.santamaria@fosjc.unesp.br.
authors.forename: Mauro Pedrine
authors.initials: MP
authors.lastname: Santamaria
mesh_terms: D000328:Adult; D000368:Aged; D002151:Calorimetry; D002921:Cicatrix / Q000473:pathology; D003238:Connective Tissue / Q000637:transplantation*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010159:Palate / Q000473:pathology*; D010789:Phototherapy; D011182:Postoperative Care; D014945:Wound Healing; D055815:Young Adult
keywords: Connective tissue graft; Gingival recession; Low-level laser therapy; Wound healing