title: Imaging Findings of an Epidermoid Cyst with Malignant Transformation to Squamous Cell Carcinoma.
abstract: We report imaging findings of a 64-year-old male patient with a ruptured epidermoid cyst (EC) known to be constant over the 23-year follow-up and showing malignant transformation to squamous cell carcinoma (SCC). Computed tomography (CT) and magnetic resonance imaging (MRI) findings including diffusion weighted imaging (DWI), 1H+MR spectroscopy (MRS), dynamic susceptibility contrast perfusion (DSC) MRI of EC, and its rare complications are presented together with a review of the literature. Fluid-lowattenuated- inversion-recovery (FLAIR) and T1-weighted images with gadolinium are the best sequences together with DWI to show the relationship of the EC, the SCC and the border between. Primary brain SCC enhances mostly ring-like or peripherally, but diffuse enhancement is also possible. To our knowledge, no MRS and DSC findings have been reported in the literature yet.
authors.affiliation: Dokuz Eylul University, School of Medicine, Department of Radiology, Izmir, Turkey.
authors.forename: Can
authors.initials: C
authors.lastname: Ozutemiz
authors.forename: Emel
authors.initials: E
authors.lastname: Ada
authors.forename: Ayca
authors.initials: A
authors.lastname: Ersen
authors.forename: Ercan
authors.initials: E
authors.lastname: Ozer
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging*; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging*; D002471:Cell Transformation, Neoplastic / Q000473:pathology*; D038524:Diffusion Magnetic Resonance Imaging; D004814:Epidermal Cyst / Q000150:complications / Q000473:pathology*; D006801:Humans; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009682:Magnetic Resonance Spectroscopy; D008297:Male; D008875:Middle Aged; D014057:Tomography, X-Ray Computed