title: Development of a Coordinatively Unsaturated Chiral Indenylruthenium Catalyst.
abstract: An unprecedented coordinatively unsaturated chiral indenylruthenium complex 12 was designed and synthesized to provide additional coordination sites for Ru-catalyzed asymmetric transformations. In an attempt to catalyze an asymmetric enyne cycloisomerization reaction of 1,6-enyne, significant amounts of hydroxycyclization were observed. Up to 84:16 er of the hydroxycyclization product was obtained in 2-MeTHF. This chiral indenylruthenium catalyst could also perform an asymmetric redox isomerization/C-H insertion reaction in up to 90:10 er.
authors.affiliation: Department of Chemistry, Stanford University , Stanford, California 94305-5080, United States.
authors.forename: Barry M
authors.initials: BM
authors.lastname: Trost
authors.affiliation: Department of Chemistry, Stanford University , Stanford, California 94305-5080, United States.
authors.forename: Michael C
authors.initials: MC
authors.lastname: Ryan
authors.affiliation: Department of Chemistry, Stanford University , Stanford, California 94305-5080, United States.
authors.forename: David
authors.initials: D
authors.lastname: Maurer
mesh_terms: D002384:Catalysis; D056831:Coordination Complexes / Q000138:chemical synthesis*; D010084:Oxidation-Reduction; D012428:Ruthenium / Q000737:chemistry*; D013237:Stereoisomerism
chemical_list: D056831:Coordination Complexes; D012428:Ruthenium