title: The critical size of hydrogen-bonded alcohol clusters as effective Brønsted bases in solutions.
abstract: The alkyl oxonium ion, which is a protonated alcohol, has long been proposed as a key reaction intermediate in alcohol dehydration. Nonetheless, the dynamics and structure of this simple but important intermediate species have not been adequately examined due to the transient nature of the oxonium ion. Here, we devised a model system for the key step in the alcohol dehydration reaction, in which a photoacid transfers a proton to alcohols of different basicity in the acetonitrile solvent. Using time-resolved spectroscopy and computation, we have found that the linkage of at least two alcohol molecules via hydrogen bonding is critical for their enhanced reactivity and extraction of the proton from the acid. This finding addresses the cooperative role of the simplest organic protic compounds, namely alcohols, in nonaqueous acid-base reactions.
authors.affiliation: Center for Soft and Living Matter, Institute for Basic Science (IBS), Ulsan 44919, Republic of Korea.
authors.forename: Sun-Young
authors.initials: SY
authors.lastname: Park
authors.forename: Taeg Gyum
authors.initials: TG
authors.lastname: Kim
authors.forename: Manjaly J
authors.initials: MJ
authors.lastname: Ajitha
authors.forename: Kijeong
authors.initials: K
authors.lastname: Kwac
authors.forename: Young Min
authors.initials: YM
authors.lastname: Lee
authors.forename: Heesu
authors.initials: H
authors.lastname: Kim
authors.forename: Yousung
authors.initials: Y
authors.lastname: Jung
authors.forename: Oh-Hoon
authors.initials: OH
authors.lastname: Kwon