title: Studies on antibacterial activities against S. aureus of chitosan metal chelates prepared in magnetic field.
abstract: In order to study the antibacterial activity of chitosan metal chelates prepared in magnetic effect, the antibacterial activities of these chelates on Staphylococcus aureus were investigated by the agar diffusion paper method. The minimum inhibition concentrations of chitosan-metal chelates were measured. With different degrees of substitution, the inhibition efficiency of the chitosan-metal chelates is different. The inhibition of chitosan on S. aureus increased with the chitosan concentration. Among the chitosan-metal chelates, the inhibition efficiency of CS-Cr is the best. The inhibition efficiency of chitosan-metal chelates prepared in the magnetic field of 400 kA/m on S. aureus is higher than the inhibition efficiency of chitosan-metal chelates prepared without the magnetic field enhanced. The minimum inhibitory concentrations are, respectively, as CS-Cu: 12.5 mg/mL, CS-Pb: 6.25 mg/mL, CS-Cr: 3.125 mg/mL. It is well known from the results that chitosan-metal chelates maybe applied in antibacterial process.
authors.affiliation: Shenzhen Second People's Hospital, Shenzhen - China.|The First Affiliated Hospital, Sun Yat-sen University, Guangzhou - China.|Shenzhen Institute of Geriatrics, Shenzhen - China.
authors.forename: Chunbao
authors.initials: C
authors.lastname: Wang
authors.affiliation: Shenzhen Second People's Hospital, Shenzhen - China.|Shenzhen Institute of Geriatrics, Shenzhen - China.
authors.forename: Lihong
authors.initials: L
authors.lastname: Duan
authors.affiliation: The First Affiliated Hospital, Sun Yat-sen University, Guangzhou - China.
authors.forename: Jian
authors.initials: J
authors.lastname: Qin
authors.affiliation: Shenzhen Second People's Hospital, Shenzhen - China.|The First Affiliated Hospital, Sun Yat-sen University, Guangzhou - China.|Shenzhen Institute of Geriatrics, Shenzhen - China.
authors.forename: Zhengzhi
authors.initials: Z
authors.lastname: Wu
authors.affiliation: College of Light Industry and Food Sciences, South China University of Technology, Guangzhou - China.
authors.forename: Siyuan
authors.initials: S
authors.lastname: Guo
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000493:pharmacokinetics; D002614:Chelating Agents / Q000737:chemistry / Q000494:pharmacology; D048271:Chitosan / Q000737:chemistry / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D019216:Metals, Heavy / Q000737:chemistry / Q000494:pharmacology; D013211:Staphylococcus aureus / Q000254:growth & development*
chemical_list: D000900:Anti-Bacterial Agents; D002614:Chelating Agents; D019216:Metals, Heavy; D048271:Chitosan