title: [YANG's pricking-cupping therapy for knee osteoarthritis: a multi-center randomized controlled trial].
abstract: OBJECTIVE
  To evaluate the clinical efficacy of YANG's pricking-cupping therapy for knee osteoar thritis (KOA). Methods This was a multi-center randomized parallel controlled trial. One hundred and seventy one patients with KOA were randomly allocated to a pricking-cupping group (89 cases) and a conventional acu puncture group (82 cases). Neixiyan (EX-LE 4), Dubi (ST 35) and ashi points were selected in the two groups. Patients in the pricking-cupping group were treated with YANG's pricking-cupping therapy; the seven-star needles were used to perform pricking at acupoints, then cupping was used until slight bleeding was observed. Patients in the conventional acupuncture group were treated with semi-standardized filiform needle therapy. The treatment was given for 4 weeks (from a minimum of 5 times to a maximum of 10 times). The follow-up visit was 4 weeks. The Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) and the visual analogue scale (VAS) were adopted for the efficacy assessments.
  
  
  RESULTS
  The pain score, stiffness score, physical function score and total score of WOMAC were all reduced after 4-week treatment and during follow-up visit in the two groups (all P<0. 0001). Except that the difference of stiffness score between the two groups was not significant after 4-week treatment (P>0. 05), each score and total score of WOMAC in the pricking-cupping group were lower than those in the conventional acupuncture group after 4-week treatment and during follow-up visit (P<0. 0001, P<0. 01). After 2-week treatment, 4-week treatment and during follow-up visit, the VAS was all reduced compared with that before treatment (all P<0. 0001) ; with the increase of the treatment, the reducing trend of VAS was more significant (P<0. 0001). The scores of VAS in the pricking-cupping group were lower than those in the conventional acupuncture group after 4-week treatment and during follow-up visit (P < 0. 01, P <0. 0001). CONCLUSION The YANG's pricking-cupping and conventional acupuncture therapy can both significantly improve knee joint pain and function in patients with KOA, which are relatively safe. The pricking cupping therapy is superior to conventional acupuncture with the identical selection of acupoints.
authors.forename: Bo
authors.initials: B
authors.lastname: Wang
authors.forename: Xiru
authors.initials: X
authors.lastname: Liu
authors.forename: Zhihai
authors.initials: Z
authors.lastname: Hu
authors.forename: Aijun
authors.initials: A
authors.lastname: Sun
authors.forename: Yanwen
authors.initials: Y
authors.lastname: Ma
authors.lastname: Chen Yingying
authors.forename: Xuzhi
authors.initials: X
authors.lastname: Zhang
authors.forename: Meiling
authors.initials: M
authors.lastname: Liu
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.forename: Shuoshuo
authors.initials: S
authors.lastname: Wang
authors.forename: Yunjia
authors.initials: Y
authors.lastname: Zhang
authors.forename: Yijing
authors.initials: Y
authors.lastname: Li
authors.forename: Weidong
authors.initials: W
authors.lastname: Shen
mesh_terms: D015670:Acupuncture Therapy; D000328:Adult; D000368:Aged; D018771:Arthralgia / Q000503:physiopathology / Q000628:therapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D007719:Knee Joint / Q000503:physiopathology; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000503:physiopathology / Q000628:therapy*; D016896:Treatment Outcome