title: From SubPAR to PAR, into the CryoEM, and More Macrolides.
abstract: Every month the editors of Cell Chemical Biology bring you highlights of the most recent chemical biology literature. Our June 2016 selection includes new efforts to map ADP-ribosylation sites and get a deeper view of their functional relevance, an illustration of why cryoEM should now be considered an important player in facilitating structure-based drug development and design, and a new way to synthesize a wide range of macrolide antibiotics.
mesh_terms: D057930:Click Chemistry; D020285:Cryoelectron Microscopy; D018942:Macrolides / Q000737:chemistry* / Q000378:metabolism; D011064:Poly Adenosine Diphosphate Ribose / Q000737:chemistry* / Q000378:metabolism; D011065:Poly(ADP-ribose) Polymerases / Q000378:metabolism
chemical_list: D018942:Macrolides; D011064:Poly Adenosine Diphosphate Ribose; D011065:Poly(ADP-ribose) Polymerases