title: CT and MR imaging features of mucinous tubular and spindle cell carcinoma of the kidneys. A multi-institutional review.
abstract: Mucinous tubular and spindle cell carcinoma (MTSCC) of the kidney is a recently identified renal malignancy. Diagnosis of this rare subtype of renal tumour can be challenging for pathologists, and as such, any additional data would be helpful to improve diagnostic reliability. As imaging features of this new and rare sub-type have not yet been clearly described, the purpose of this study was to describe the main radiologic features on computed tomography (CT) and magnetic resonance imaging (MRI), based jointly on the literature and findings from a multi-institutional retrospective review of pathology and imaging databases. Using a combination of CT/MRI features, diagnosis of MTSCC could be suggested in many cases. A combination of slow enhancement with plateau on dynamic contrast-enhanced CT/MRI, intermediate to high T2 signal intensity contrasting with low apparent diffusion coefficient values on MRI appeared evocative of this diagnosis.
  
  
  CONCLUSIONS
  • A slow enhancement with plateau is observed either on CT or MRI. • High T2 signal components but low apparent coefficient diffusion are evocative. • T2-weighted imaging features depend on the mucin components of the tumour.
authors.affiliation: Department of Radiology, Pellegrin Hospital, Place Amélie Raba Léon, 33076, Bordeaux, France. francois.cornelis@chu-bordeaux.fr.
authors.forename: F
authors.identifier: http://orcid.org/0000-0002-1058-0884
authors.initials: F
authors.lastname: Cornelis
authors.affiliation: Department of Pathology, Pasteur Hospital, 30 av. de la Voie Romaine, 06002, Nice, France.
authors.forename: D
authors.initials: D
authors.lastname: Ambrosetti
authors.affiliation: Department of Radiology, Kremlin-Bicêtre Hospital, 78 rue du Général Leclerc, 94275, Paris, France.
authors.forename: L
authors.initials: L
authors.lastname: Rocher
authors.affiliation: Department of Health Sciences (DISSAL), University of Genoa, IRCCS AOU Ospedale, San Martino IST, Largo R. Benzi, 10, I-16132, Genoa, Italy.
authors.forename: L E
authors.initials: LE
authors.lastname: Derchi
authors.affiliation: Department of Radiology, Claude Huriez Hospital, 1 place de Verdun, 59037, Lille, France.
authors.forename: B
authors.initials: B
authors.lastname: Renard
authors.affiliation: Department of Radiology, Claude Huriez Hospital, 1 place de Verdun, 59037, Lille, France.
authors.forename: P
authors.initials: P
authors.lastname: Puech
authors.affiliation: Department of Radiology, Brabois Hospital, rue du Morvan, 54511, Vandoeuvre-lès-Nancy, France.
authors.forename: M
authors.initials: M
authors.lastname: Claudon
authors.affiliation: Department of Radiology, E. Herriot Hospital, 5 Place d'Arsonval, 69437, Lyon, France.
authors.forename: O
authors.initials: O
authors.lastname: Rouvière
authors.affiliation: Department of Pathology, Kremlin-Bicêtre Hospital, 78 rue du Général Leclerc, 94275, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Ferlicot
authors.affiliation: Department of Radiology, Civil Hospital, 1 place de l'Hôpital, 67091, Strasbourg, France.
authors.forename: C
authors.initials: C
authors.lastname: Roy
authors.affiliation: Department of Pathology, Pellegrin Hospital, Place Amélie Raba Léon, 33076, Bordeaux, France.
authors.forename: M
authors.initials: M
authors.lastname: Yacoub
authors.affiliation: Department of Radiology, Pellegrin Hospital, Place Amélie Raba Léon, 33076, Bordeaux, France.
authors.forename: N
authors.initials: N
authors.lastname: Grenier
authors.affiliation: Department of Urologic Surgery, Pellegrin Hospital, Place Amélie Raba Léon, 33076, Bordeaux, France.
authors.forename: J C
authors.initials: JC
authors.lastname: Bernhard
mesh_terms: D002288:Adenocarcinoma, Mucinous / Q000000981:diagnostic imaging* / Q000473:pathology; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007680:Kidney Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D009077:Mucins; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014057:Tomography, X-Ray Computed
chemical_list: D009077:Mucins
keywords: Kidney; Magnetic resonance imaging; Mucinous tubular and spindle cell carcinoma of kidney; Renal cell carcinoma; Tumour