title: Two rare diagnoses during chronic lymphocytic leukaemia follow-up: Kaposi's sarcoma and Merkel cell carcinoma.
abstract: Chronic lymphocytic leukaemia often has a clinical presentation characterised by increased neoplastic lymphocytes which are mostly mature looking due to B lymphocytes. Increased secondary cancer prevalence has been detected among patients with chronic lymphocytic leukaemia diagnosis. In this report, we present three chronic lymphocytic leukaemia patients who developed secondary rare cancers during their follow-up at our clinic. Case 1: A 54-year-old female patient was diagnosed with stage I chronic lymphocytic leukaemia in 2003 and was diagnosed with Merkel cell carcinoma in February 2013. Case 2: A 66-year-old male patient was diagnosed with stage II chronic lymphocytic leukaemia in 2009 and was diagnosed with Kaposi's sarcoma in March 2013. Case 3: A 77-year-old male patient was diagnosed with stage I chronic lymphocytic leukaemia in 2006 and was diagnosed with Kaposi's sarcoma in 2011. In conclusion, secondary cancers are observed in patients diagnosed with chronic lymphocytic leukaemia. Therefore, follow-up of chronic lymphocytic leukaemia requires additional attention in this context.
authors.affiliation: MD (Medical Doctor), Clinic of Hematology, Istanbul Training and Research Hospital, Turkey mhdogu@yahoo.com.
authors.forename: Mehmet H
authors.initials: MH
authors.lastname: Dogu
authors.affiliation: MD (Medical Doctor), Department of Hematology, Pamukkale University Faculty of Medicine, Turkey.
authors.forename: Ismail
authors.initials: I
authors.lastname: Sari
authors.affiliation: MD (Medical Doctor), Department of Hematology, Pamukkale University Faculty of Medicine, Turkey.
authors.forename: Sibel
authors.initials: S
authors.lastname: Hacioglu
authors.affiliation: MD (Medical Doctor), Department of Medical Oncology, Pamukkale University Faculty of Medicine, Turkey.
authors.forename: Serkan
authors.initials: S
authors.lastname: Degirmencioglu
authors.affiliation: MD (Medical Doctor), Department of Pathology, Pamukkale University Faculty of Medicine, Turkey.
authors.forename: Nilay
authors.initials: N
authors.lastname: Şen
authors.affiliation: MD (Medical Doctor), Department of Hematology, Pamukkale University Faculty of Medicine, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Keskin
mesh_terms: D000368:Aged; D015266:Carcinoma, Merkel Cell / Q000473:pathology / Q000556:secondary*; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D015451:Leukemia, Lymphocytic, Chronic, B-Cell / Q000150:complications* / Q000188:drug therapy; D008297:Male; D008875:Middle Aged; D012514:Sarcoma, Kaposi / Q000473:pathology / Q000532:radiotherapy / Q000556:secondary*; D012878:Skin Neoplasms / Q000473:pathology / Q000556:secondary*; D016896:Treatment Outcome
keywords: Chronic lymphocytic leukaemia; Kaposi’s sarcoma; Merkel cell carcinoma