title: Oral lichen planus.
abstract: Lichen planus is an inflammatory mucocutaneous disease that can affect the skin, hair, nails, and mucosal surfaces. Mucosal sites of involvement include oral, genital, ocular, otic, esophageal, and, less commonly, bladder, nasal, laryngeal, and anal surfaces. Oral lichen planus is a mucosal variant of lichen planus, which tends to affect women more often than men, with a typically more chronic course and potential for significant morbidity. Treatment can be challenging, and there is potentially a low risk of malignant transformation; however, therapeutic benefits can be obtained with various topical and systemic medications. Clinical monitoring is recommended to ensure symptomatic control. Increasing awareness and recognition of this entity have continued to fuel advances in therapy and in our understanding of the disease.
authors.affiliation: Department of Dermatology, Mayo Clinic, Rochester, MN.
authors.forename: Meredith A
authors.initials: MA
authors.lastname: Olson
authors.affiliation: Department of Dermatology, Mayo Clinic, Scottsdale, AZ.
authors.forename: Roy S
authors.initials: RS
authors.lastname: Rogers
authors.affiliation: Department of Dermatology, Mayo Clinic, Jacksonville, FL. Electronic address: Bruce.Alison@mayo.edu.
authors.forename: Alison J
authors.initials: AJ
authors.lastname: Bruce
mesh_terms: D000284:Administration, Oral; D000287:Administration, Topical; D000305:Adrenal Cortex Hormones / Q000008:administration & dosage / Q000627:therapeutic use*; D001688:Biological Products / Q000627:therapeutic use*; D065095:Calcineurin Inhibitors / Q000008:administration & dosage / Q000627:therapeutic use*; D002471:Cell Transformation, Neoplastic; D005260:Female; D005831:Genital Diseases, Female / Q000209:etiology; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D017676:Lichen Planus, Oral / Q000175:diagnosis* / Q000188:drug therapy* / Q000209:etiology; D012307:Risk Factors
chemical_list: D000305:Adrenal Cortex Hormones; D001688:Biological Products; D065095:Calcineurin Inhibitors; D007166:Immunosuppressive Agents