title: New Ventricular Septal Defects Following Balloon-Expandable Transcatheter Aortic Valve Replacement.
abstract: Transcatheter aortic valve replacement (TAVR) has been commercially approved in the United States for the treatment of high-risk and inoperable patients with severe symptomatic aortic stenosis. While TAVR has proven benefits with regard to survival and quality of life in studied populations, the procedure is also associated with several well-described complications including stroke, vascular injury, and paravalvular regurgitation. More infrequent complications are less well described. Here, we report the development of new ventricular septal defects after TAVR in 4 patients with left ventricular outflow tract calcification. We discuss imaging and post-TAVR management of these patients.
authors.forename: A Garvey
authors.initials: AG
authors.lastname: Rene
authors.forename: Dinesh
authors.initials: D
authors.lastname: Jagasia
authors.forename: S Rasi
authors.initials: SR
authors.lastname: Wickramasinghe
authors.forename: Nimesh
authors.initials: N
authors.lastname: Desai
authors.forename: Wilson
authors.initials: W
authors.lastname: Szeto
authors.forename: Prashanth
authors.initials: P
authors.lastname: Vallabhajosyula
authors.forename: Robert H
authors.initials: RH
authors.lastname: Li
authors.forename: Frank E
authors.initials: FE
authors.lastname: Silvestry
authors.forename: Jay
authors.initials: J
authors.lastname: Giri
authors.forename: Saurabh
authors.initials: S
authors.lastname: Jha
authors.forename: Howard C
authors.initials: HC
authors.lastname: Herrmann
authors.affiliation: The Division of Cardiology, University of Pennsylvania Medical Center, 3400 Spruce 9 Gates, Philadelphia, PA 19104 USA. saif.anwaruddin@uphs.upenn.edu.
authors.forename: Saif
authors.initials: S
authors.lastname: Anwaruddin
mesh_terms: D000369:Aged, 80 and over; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000175:diagnosis / Q000453:epidemiology / Q000523:psychology / Q000601:surgery; D004452:Echocardiography / Q000379:methods; D005260:Female; D006345:Heart Septal Defects, Ventricular / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000601:surgery; D006801:Humans; D008297:Male; D010043:Outcome and Process Assessment, Health Care; D011183:Postoperative Complications / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery; D011788:Quality of Life; D012086:Reoperation / Q000379:methods; D018570:Risk Assessment / Q000379:methods; D012307:Risk Factors; D012720:Severity of Illness Index; D065467:Transcatheter Aortic Valve Replacement / Q000009:adverse effects / Q000379:methods