title: Cushing's Syndrome Masquerading as Treatment Resistant Depression.
abstract: Treatment resistant depression (TRD) is a common clinical occurrence among patients treated for major depressive disorder. A significant proportion of patients remain significantly depressed in spite of aggressive pharmacological and psychotherapeutic approaches. Management of patient with treatment resistant depression requires thorough evaluation for physical causes. We report a case of recurrent depressive disorder, who presented with severe depressive episode without psychotic symptoms, not responding to multiple adequate trials of antidepressants, who on investigation was found to have Cushing's syndrome and responded well to Ketoconazole.
authors.affiliation: Department of Psychiatry, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur, Karnataka, India.
authors.forename: B N
authors.initials: BN
authors.lastname: Anil Kumar
authors.affiliation: Department of Psychiatry, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
authors.forename: Sandeep
authors.initials: S
authors.lastname: Grover
keywords: Antiglucocorticoid drugs; Cushing's syndrome; treatment-resistant depression