title: Wh- questions and passive sentences in non-fluent variant PPA and semantic variant PPA: Longitudinal findings of an anagram production task.
abstract: Using an anagram task, we investigated longitudinal syntactic production by individuals with semantic variant primary progressive aphasia (svPPA) and non-fluent variant PPA (nfvPPA), compared to controls. The accuracy of the production of active and passive, and reversible and non-reversible sentences, as well as of wh- questions was compared across the three groups. Results showed a different pattern of syntactic impairment across the two patient groups. The nfvPPA group showed difficulty with wh- questions at Time 1 and impairment with the passive structure approximately one year later, at Time 2. Surprisingly, the svPPA group also showed difficulty with wh- questions from Time 1, but still no difficulty on passive sentences, two years later, at Time 3. Neither group had difficulty with reversibility. The results of the nfvPPA patients were as expected, and the results of the svPPA patients suggest that this group may exhibit a greater syntactic impairment than is typically recognized.
authors.affiliation: a Department of Speech-Language Pathology , Faculty of Medicine, University of Toronto , Toronto , ON , Canada.|b Toronto Rehabilitation Institute-University Health Network (TRI-UHN) , Toronto , ON , Canada.
authors.forename: Jennifer
authors.initials: J
authors.lastname: Cupit
authors.affiliation: a Department of Speech-Language Pathology , Faculty of Medicine, University of Toronto , Toronto , ON , Canada.|b Toronto Rehabilitation Institute-University Health Network (TRI-UHN) , Toronto , ON , Canada.
authors.forename: Naida L
authors.initials: NL
authors.lastname: Graham
authors.affiliation: a Department of Speech-Language Pathology , Faculty of Medicine, University of Toronto , Toronto , ON , Canada.|c Audiology and Speech-Language Pathology Program , University of Ottawa , Ottawa , Canada.
authors.forename: Carol
authors.initials: C
authors.lastname: Leonard
authors.affiliation: d Toronto Western Hospital-University Health Network (TWH-UHN) , Toronto , ON , Canada.|j Department of Medicine (Neurology) , University of Toronto , Toronto , Canada.
authors.forename: David
authors.initials: D
authors.lastname: Tang-Wai
authors.affiliation: e Sunnybrook Health Sciences Centre , Toronto , ON , Canada.|f Institute of Medical Science, University of Toronto , Toronto , ON , Canada.|g L.C. Campbell Cognitive Neurology Research Unit , Sunnybrook Health Sciences Centre , Toronto , ON , Canada.|h Brain Sciences Research Program , Sunnybrook Research Institute , Toronto , ON , Canada.|i Rotman Research Institute-Baycrest Centre , Toronto , ON , Canada.|j Department of Medicine (Neurology) , University of Toronto , Toronto , Canada.|k Heart and Stroke Foundation , Partnership for Stroke Recovery , Ontario , ON , Canada.
authors.forename: Sandra E
authors.initials: SE
authors.lastname: Black
authors.affiliation: a Department of Speech-Language Pathology , Faculty of Medicine, University of Toronto , Toronto , ON , Canada.|b Toronto Rehabilitation Institute-University Health Network (TRI-UHN) , Toronto , ON , Canada.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Rochon
mesh_terms: D000368:Aged; D018888:Aphasia, Primary Progressive / Q000503:physiopathology*; D005260:Female; D006801:Humans; D007802:Language; D008297:Male; D012660:Semantics
keywords: Syntactic production; constrained anagram task; non-fluent variant primary progressive aphasia; primary progressive aphasia; semantic variant primary progressive aphasia