title: Evaluation of center-cut separations applying simulated moving bed chromatography with 8 zones.
abstract: Different multi-column options to perform continuous chromatographic separations of ternary mixtures have been proposed in order to overcome limitations of batch chromatography. One attractive option is given by simulated moving bed chromatography (SMB) with 8 zones, a process that offers uninterrupted production, and, potentially, improved economy. As in other established ternary separation processes, the separation sequence is crucial for the performance of the process. This problem is addressed here by computing and comparing optimal performances of the two possibilities assuming linear adsorption isotherms. The conclusions are presented in a decision tree which can be used to guide the selection of system configuration and operation.
authors.affiliation: Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, DE-39106 Magdeburg, Germany.
authors.forename: Francisco Vitor
authors.initials: FV
authors.lastname: Santos da Silva
authors.affiliation: Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Sandtorstrasse 1, DE-39106 Magdeburg, Germany; Chemical Process Engineering, Otto von Guericke Universität, Universitätsplatz 2, DE-39106 Magdeburg, Germany. Electronic address: seidel@mpi-magdeburg.mpg.de.
authors.forename: Andreas
authors.initials: A
authors.lastname: Seidel-Morgenstern
mesh_terms: D000327:Adsorption; D000465:Algorithms; D002845:Chromatography / Q000191:economics / Q000295:instrumentation* / Q000379:methods; D003198:Computer Simulation; D003663:Decision Trees; D057168:Distillation; D004526:Efficiency; D018803:Models, Economic; D015203:Reproducibility of Results; D013816:Thermodynamics
keywords: 8 zone simulated moving bed chromatography; 8 zone true moving bed analogy; Equilibrium stage model; Optimization; Separation sequence; Ternary separation