title: Psychosis Following an Increase in Intrathecal Baclofen.
abstract: Baclofen is a commonly used medication to treat spasticity in neurologic disorders. In the traumatic brain injury (TBI) population, the intrathecal administration of baclofen is often preferred over oral administration due to cognitive side effects. Here we report on a case of a psychotic episode following an increase in intrathecal baclofen in a young man with a history of a TBI. Although intrathecal baclofen is commonly used and is generally well tolerated, this case highlights an important potential effect of intrathecal baclofen that has rarely been reported in the literature.
  
  
  
  V.
authors.affiliation: Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine and Rehabilitation Institute of Chicago, Chicago, IL(∗).
authors.forename: Mithra B
authors.initials: MB
authors.lastname: Maneyapanda
authors.affiliation: Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine and Rehabilitation Institute of Chicago, Chicago, IL(†).
authors.forename: Sangeeta Patel
authors.initials: SP
authors.lastname: Driver
authors.affiliation: Department of Physical Medicine and Rehabilitation, Northwestern University Feinberg School of Medicine and Rehabilitation Institute of Chicago, Chicago, IL(‡).
authors.forename: David L
authors.initials: DL
authors.lastname: Ripley
authors.affiliation: Department of Psychiatry and Behavioral Sciences, Northwestern University Feinberg School of Medicine, Chicago, IL(§).
authors.forename: Robert
authors.initials: R
authors.lastname: Lloyd
authors.affiliation: Department of Physical Medicine and Rehabilitation, Northwestern University, McGaw Medical Center, Feinberg School of Medicine and Rehabilitation Institute of Chicago, 345 East Superior Street, Chicago, IL 60611(‖). Electronic address: nbrkic@ric.org.
authors.forename: Nenad
authors.initials: N
authors.lastname: Brkic
mesh_terms: D001418:Baclofen; D000070642:Brain Injuries, Traumatic; D006801:Humans; D007278:Injections, Spinal; D008297:Male; D009125:Muscle Relaxants, Central; D009128:Muscle Spasticity; D011618:Psychotic Disorders
chemical_list: D009125:Muscle Relaxants, Central; D001418:Baclofen