title: Hemodynamic and metabolic response during dynamic and resistance exercise in different intensities: a cross-sectional study on implications of intensity on safety and symptoms in patients with coronary disease.
abstract: Resistance (RE) and aerobic exercise (AE) can promote hemodynamic, physiologic and clinical modifications in coronary artery disease (CAD) patients. The aim of the study is to assess key physiologic and clinical responses during RE at 30% and 60% of 1-RM on a 45° leg press and to compare responses during AE. We evaluated fifteen male subjects with coronary artery disease (60.8±4.7 years) that performed the following tests: (1) incremental AE test on cycle ergometer; (2) 1-RM test on a leg press at 45°; (3) and RE at 30% and 60% of 1-RM for 24 repetitions. Peak cardiac output (CO), heart rate (HR), oxygen consumption (VO2), carbon dioxide production (VCO2) and the minute ventilation (VE, L/min)/VCO2 ration were measured. We found that both AE and RE at 60% of aerobic and resistance capacity elicited similar hemodynamic and ventilatory responses (p>0.05). However, RE at 30% 1-RM showed more attenuated responses of VO2, VE/VCO2, HR and CO when compared with 60% of aerobic and resistance capacity. Interestingly, the number, percentage and the severity of arrhythmias were higher at 60% 1-RM (P<0.05). Our data suggest that high repetition sets of RE at 60% 1-RM appears to result in hemodynamic, ventilatory, and metabolic changes equivalent to those observed during AE at a comparable intensity.
authors.affiliation: Cardiopulmonary Physical Therapy Laboratory Brazil.
authors.forename: Flavia Rossi
authors.initials: FR
authors.lastname: Caruso
authors.affiliation: Department of Bioengineering USP, Brazil.
authors.forename: Jose Carlos Bonjorno
authors.initials: JC
authors.lastname: Junior
authors.affiliation: Cardiopulmonary Physical Therapy Laboratory Brazil.
authors.forename: Renata G
authors.initials: RG
authors.lastname: Mendes
authors.affiliation: Department of Bioengineering USP, Brazil.
authors.forename: Milena Pelosi
authors.initials: MP
authors.lastname: Sperling
authors.affiliation: Department of Bioengineering USP, Brazil.
authors.forename: Vivian M
authors.initials: VM
authors.lastname: Arakelian
authors.affiliation: Cardiopulmonary Physical Therapy Laboratory Brazil.
authors.forename: Daniela
authors.initials: D
authors.lastname: Bassi
authors.affiliation: Department of Physical Therapy and Integrative Physiology Laboratory, College of Applied Health Sciences, University of Illinois at Chicago USA.
authors.forename: Ross
authors.initials: R
authors.lastname: Arena
authors.affiliation: Cardiopulmonary Physical Therapy LaboratoryBrazil; Department of BioengineeringUSP, Brazil.
authors.forename: Audrey
authors.initials: A
authors.lastname: Borghi-Silva
keywords: Cardiac rehabilitation; coronary artery disease; resistance exercise