title: A new cervical artificial disc prosthesis based on physiological curvature of end plate: a finite element analysis.
abstract: The study aimed to build a new cervical artificial disc C3-C7 segment prosthesis, and perform a biomechanical comparison between the new prosthesis and the Prestige LP prosthesis using a three-dimensional non-linear finite element (FE) model.
  
  
  
  The study compared the biomechanical differences between the new cervical artificial disc prosthesis based on the physiological curvature of the end plate and the Prestige LP prosthesis after artificial disc replacement.
  
  
  
  There has been no prior research on artificial disc prostheses based on the physiological curvature of the end plate; studies of biomechanical changes after cervical disc arthroplasty (CDR) are few.
  
  
  
  An FE model of the C3-C7 segments was developed and validated. A new cervical artificial disc prosthesis based on the physiological curvature of the end plate and the Prestige LP prosthesis were integrated at the C5-C6 segment into the validated FE model. All models were subjected to a follower load of 73.6 N and a 1 Nm in flexion-extension, lateral bending, and axial torsion. The segmental range of motion (ROM) and stress on the prostheses were analyzed.
  
  
  
  The ROM in most segments after CDR with new cervical artificial disc prosthesis was more similar to that of the normal cervical spine than the Prestige LP prosthesis. However, there was no significant difference between the two prostheses. The stress on the new artificial disc was significantly less than that in the Prestige LP prosthesis.
  
  
  
  There was no significant difference in ROM in all segments after CDR for the two prostheses. The stress on the new cervical artificial disc prosthesis based on the physiological curvature of the end plate was significantly less than that in the Prestige LP prosthesis. The new artificial disc prosthesis is feasible and effective, and can reduce the implant-bone interface stress on the end plate, which may be one of the causes of prosthesis subsidence.
authors.affiliation: Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
authors.forename: Cheng-Cheng
authors.initials: CC
authors.lastname: Yu
authors.affiliation: Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Liu
authors.affiliation: Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
authors.forename: Da-Geng
authors.initials: DG
authors.lastname: Huang
authors.affiliation: Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
authors.forename: Yong-Hong
authors.initials: YH
authors.lastname: Jiang
authors.affiliation: Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China.
authors.forename: Hang
authors.initials: H
authors.lastname: Feng
authors.affiliation: Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University Health Science Center, No. 76 Nanguo Rd, Xi'an, Shaanxi 710054, China. Electronic address: yccxiafeng@163.com.
authors.forename: Ding-Jun
authors.initials: DJ
authors.lastname: Hao
mesh_terms: D000328:Adult; D001696:Biomechanical Phenomena; D002574:Cervical Vertebrae / Q000033:anatomy & histology / Q000601:surgery*; D003198:Computer Simulation; D020342:Finite Element Analysis; D006801:Humans; D007403:Intervertebral Disc / Q000033:anatomy & histology / Q000601:surgery*; D008297:Male; D019736:Prostheses and Implants / Q000009:adverse effects* / Q000592:standards; D016059:Range of Motion, Articular; D059145:Total Disc Replacement / Q000295:instrumentation* / Q000379:methods
keywords: Cervical artificial disc replacement; End plate; Finite element analysis; Physiological curvature; Prosthesis; Range of segmental motion; Stress