title: Iridium/N-heterocyclic carbene-catalyzed C-H borylation of arenes by diisopropylaminoborane.
abstract: Catalytic C-H borylation of arenes has been widely used in organic synthesis because it allows the introduction of a versatile boron functionality directly onto simple, unfunctionalized arenes. We report herein the use of diisopropylaminoborane as a boron source in C-H borylation of arenes. An iridium(I) complex with 1,3-dicyclohexylimidazol-2-ylidene is found to efficiently catalyze the borylation of arenes and heteroarenes. The resulting aminoborylated products can be converted to the corresponding boronic acid derivatives simply by treatment with suitable diols or diamines.
authors.affiliation: Center for Atomic and Molecular Technologies, Graduate School of Engineering, Osaka University, Osaka 565-0871, Japan; Department of Applied Chemistry, Faculty of Engineering, Osaka University, Osaka 565-0871, Japan.
authors.forename: Mamoru
authors.initials: M
authors.lastname: Tobisu
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Osaka 565-0871, Japan.
authors.forename: Takuya
authors.initials: T
authors.lastname: Igarashi
authors.affiliation: Department of Applied Chemistry, Faculty of Engineering, Osaka University, Osaka 565-0871, Japan.
authors.forename: Naoto
authors.initials: N
authors.lastname: Chatani
keywords: C–H borylation; N-heterocyclic carbene; boronic acid; iridium