title: Small Drops Get Fat: Unexpected Fatty Acid in Cytoplasmic Lipid Droplets.
abstract: In a model of transcellular lipid biosynthesis, Guijas et al. (2016), in this issue of Cell Chemical Biology, demonstrate that lipid droplet-containing "foamy" monocytes unexpectedly accumulate 16:1n9-palmitoleic acid, which has anti-inflammatory function in vitro and in vivo. This uncommon positional isomer of 16:1n7-palmitoleic acid represents a candidate biomarker for early cardiovascular disease detection.
authors.affiliation: Department of Urology, Medical University of Innsbruck, 6020 Innsbruck, Austria. Electronic address: martin.thurnher@i-med.ac.at.
authors.forename: Martin
authors.initials: M
authors.lastname: Thurnher
mesh_terms: D015415:Biomarkers; D002318:Cardiovascular Diseases; D005227:Fatty Acids; D006801:Humans; D066292:Lipid Droplets; D008055:Lipids; D009000:Monocytes
chemical_list: D015415:Biomarkers; D005227:Fatty Acids; D008055:Lipids