title: Red cell distribution width and neutrophil-to-lymphocyte ratio predict left ventricular dysfunction in acute anterior ST-segment elevation myocardial infarction.
abstract: OBJECTIVE
  Red cell distribution width (RDW) and neutrophil-to-lymphocyte ratio (NLR) are the two markers used to determine risk of mortality and adverse cardiovascular outcomes in patients with acute myocardial infarction. The relationship between RDW, NLR, and left ventricular (LV) systolic functions has not been reported. In this report, we aimed to investigate the relationship between RDW, NLR, and LV systolic function in anterior ST-segment elevation myocardial infarction (STEMI) patients who underwent primary percutaneous coronary intervention (PCI).
  
  
  METHODS
  RDW and NLR were measured on admission in 106 STEMI patients treated with primary PCI. Patients were divided into two groups according to left ventricular ejection fraction (LVEF), as Group I (systolic dysfunction, LVEF <50%) and Group II (preserved global left ventricle systolic function, LVEF ⩾50%). The first group included 47 patients and the second group included 59 patients.
  
  
  RESULTS
  Mean RDW and NLR were significantly higher in Group I compared to Group II [13.7 ± 0.9% vs. 13.4 ± 0.7%, p = 0.03 and 5.86 (range, 0.66-40.50) vs. 2.75 (range, 0.51-39.39), p = 0.013, respectively].
  
  
  CONCLUSIONS
  Increased RDW and NLR on admission, in anterior STEMI patients treated with primary PCI are associated with LV systolic dysfunction.
authors.affiliation: Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Mustafa Serkan
authors.initials: MS
authors.lastname: Karakas
authors.affiliation: Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Necmettin
authors.initials: N
authors.lastname: Korucuk
authors.affiliation: Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Veysel
authors.initials: V
authors.lastname: Tosun
authors.affiliation: Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Refik Emre
authors.initials: RE
authors.lastname: Altekin
authors.affiliation: Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Fatih
authors.initials: F
authors.lastname: Koç
authors.affiliation: Department of Cardiology, Ahi Evran University Education and Research Hospital, Kırşehir, Turkey.
authors.forename: Sinan Cemgil
authors.initials: SC
authors.lastname: Ozbek
authors.affiliation: Department of Biostatistics and Medical Informatics, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Ozel
authors.affiliation: Department of Cardiology, Akdeniz University Medical Faculty, Dumlupinar Bouleward, Konyaaltı, Antalya, Turkey.
authors.forename: Cengiz
authors.initials: C
authors.lastname: Ermis
keywords: Myocardial infarction; Neutrophil-to-lymphocyte ratio; Primary percutaneous coronary intervention; Red cell distribution width; Systolic dysfunction