title: Comparative studies on extracts fromHericium erinaceusby different polarity reagents to gain higher antioxidant activities.
abstract: Hericium erinaceus (H. erinaceus)is a source of exogenous antioxidants that has been traditionally used in China for the prevention and treatment of oxidative stress-associated disease. In the present study, the bioactive compounds ofH. erinaceuswere extracted with the following eight representative reagents: n-Hexane, xylene, chloroform, anhydrous ether, ethyl acetate, acetone, anhydrous ethanol and distilled water. Thein vitroantioxidant activities were also evaluated. All of the extracted compounds exhibited reducing power and scavenging activity against 1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide anion free radicals. In addition, the antioxidant capacities varied with the used chemical reagents and exhibited dose-dependent effects. Extracts from anhydrous ethanol, chloroform and acetone were capable of inhibiting lipid peroxidation. The anhydrous ethanol extracts were observed to have significant levels of antioxidant compounds since they had a strong reducing power, high scavenging rates against DPPH and superoxide anion-free radicals (>90%), and high inhibition rates on lipid peroxidation (>60%). The present study will provide reference data for the antioxidant applications ofH. erinaceusin pharmaceutical use and disease prevention.
authors.affiliation: College of Life Science, Anhui Science and Technology University, Fengyang, Anhui 233100, P.R. China.
authors.forename: Shengjuan
authors.initials: S
authors.lastname: Jiang
authors.affiliation: College of Life Science, Anhui Science and Technology University, Fengyang, Anhui 233100, P.R. China.
authors.forename: Yuliang
authors.initials: Y
authors.lastname: Wang
authors.affiliation: College of Life Science, Anhui Science and Technology University, Fengyang, Anhui 233100, P.R. China.
authors.forename: Xiaolong
authors.initials: X
authors.lastname: Zhang
keywords: Hericium erinaceus; antioxidant activity; extractions; homeostasis; polarity