title: A study to evaluate the effect of different mandibular horizontal and vertical jaw positions on sleep parameters in patients with obstructive sleep apnea.
abstract: OBJECTIVE
  The worldwide prevalence of obstructive sleep apnea (OSA) is increasing day by day and is estimated to be as prevalent as asthma and diabetes. Untreated sleep apnea can have dire health consequences and can increase risk of hypertension, diabetes, heart disease, and heart failure. Dentists are often the first professional to become aware of a potential problem since they are usually in contact with their patients more frequently than are physicians. The present study was aimed at evaluating the effect of four different mandibular advancement splints fabricated at different jaw positions on sleep parameters in patients with OSA.
  
  
  METHODS
  72 patients who fulfilled the study criteria were selected. All the patients were randomly divided into four groups of 18 patients each. All the patients in group 1 were given a mandibular advancement splint (MAS) fabricated at 60% of maximum protrusion and 4 mm of vertical opening. All the patients in group 2 were given a MAS fabricated at 60% of maximum protrusion and 6 mm of vertical opening. All the patients in group 3 were given a MAS fabricated at 70% of maximum protrusion and 4 mm of vertical opening. All the patients in group 4 were given a MAS fabricated at 70% of maximum protrusion and 6 mm of vertical opening.
  
  
  RESULTS
  The maximum change in all the sleep parameters was observed in group 3 when MAS was fabricated at 70% of maximum protrusion and 4 mm of vertical opening.
  
  
  CONCLUSIONS
  The present study suggested that MAS was more effective with no patient discomfort when fabricated at 70% of maximum protrusion and 4 mm of vertical jaw separation.
authors.forename: Ashutosh
authors.initials: A
authors.lastname: Gupta
authors.forename: Arvind
authors.initials: A
authors.lastname: Tripathi
authors.forename: Chhavi
authors.initials: C
authors.lastname: Trivedi
authors.forename: Piyush
authors.initials: P
authors.lastname: Sharma
authors.forename: Avinash
authors.initials: A
authors.lastname: Mishra
mesh_terms: D005260:Female; D006801:Humans; D008297:Male; D019186:Mandibular Advancement / Q000295:instrumentation*; D008875:Middle Aged; D017090:Occlusal Splints; D011474:Prosthesis Design; D020181:Sleep Apnea, Obstructive / Q000517:prevention & control*; D016896:Treatment Outcome; D014716:Vertical Dimension