title: Hemolytic Uremic Syndrome Causing Multicystic Leukoencephalomalacia.
abstract: BACKGROUND
  Hemolytic uremic syndrome is a disease characterized by hemolytic anemia, thrombocytopenia and acute renal failure with multiple organ involvement. Central nervous system involvement is detected in 20-50% of the patients and this leads to increased morbidity and mortality.
  
  
  METHODS
  We report the neuroimaging findings in a four-month-old male with hemolytic uremic syndrome. The cerebral cortex and white matter showed mild signal intensity on T2-weighted images. The diffusion weighted imaging demonstrated restricted diffusion in the cerebral cortex and white matter with corresponding low signal intensity on the apparent diffusion coefficient maps representing cytotoxic edema. These findings ended in multicystic leukoencephalomalacia.
  
  
  CONCLUSIONS
  In hemolytic uremic syndrome with brain involvement symptoms develop due to the different level of actions of factors and thus MRI protocol towards cerebral parenchyma should include DWI, especially in pediatric patients.
authors.affiliation: Department of Radiology, Yuzuncuyil University Dursun Odabas Medical Center, Van Sehri, Turkey.
authors.forename: Abdussamet
authors.initials: A
authors.lastname: Batur
authors.affiliation: Department of Radiology, Yuzuncuyil University Dursun Odabas Medical Center, Van Sehri, Turkey.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Alpaslan
authors.affiliation: Department of Radiology, Yuzuncuyil University Dursun Odabas Medical Center, Van Sehri, Turkey.
authors.forename: Alpaslan
authors.initials: A
authors.lastname: Yavuz
authors.affiliation: Department of Radiology, Yuzuncuyil University Dursun Odabas Medical Center, Van Sehri, Turkey.
authors.forename: Aydın
authors.initials: A
authors.lastname: Bora
authors.affiliation: Department of Radiology, Yuzuncuyil University Dursun Odabas Medical Center, Van Sehri, Turkey.
authors.forename: Mehmet Deniz
authors.initials: MD
authors.lastname: Bulut
keywords: Brain; Hemolytic-Uremic Syndrome; Leukoencephalopathies; Magnetic Resonance Imaging