title: Near Catastrophic Accelerated Structural Degeneration of the Perimount Magna Pericardial Bioprosthesis in Children.
abstract: Experience with pericardial bioprostheses in young patients is limited. Accelerated degeneration of the Mitroflow valve has recently been reported. We report early accelerated structural valve degeneration with the Perimount Magna bioprosthesis, which has not been previously reported. Young patients with the Magna bioprosthesis are at high risk for rapid progression to severe stenosis, which underscores their need for more vigilant surveillance. The benefits and risks of these bioprosthetic valves must be weighed carefully when options for replacement in these young patients are discussed.
authors.affiliation: Division of Pediatric Cardiology, University of Tennessee Health Sciences Center and Le Bonheur Children's Hospital, Memphis, Tennessee. Electronic address: rphilip@uthsc.edu.
authors.forename: Ranjit
authors.initials: R
authors.lastname: Philip
authors.affiliation: Division of Pediatric Cardiac Surgery, University of Tennessee Health Sciences Center and Le Bonheur Children's Hospital, Memphis, Tennessee.
authors.forename: T K Susheel
authors.initials: TK
authors.lastname: Kumar
authors.affiliation: Division of Pediatric Cardiology, University of Tennessee Health Sciences Center and Le Bonheur Children's Hospital, Memphis, Tennessee.
authors.forename: B Rush
authors.initials: BR
authors.lastname: Waller
authors.affiliation: Division of Pediatric Cardiac Surgery, University of Tennessee Health Sciences Center and Le Bonheur Children's Hospital, Memphis, Tennessee.
authors.forename: Mia
authors.initials: M
authors.lastname: McCoy
authors.affiliation: Division of Pediatric Cardiac Surgery, University of Tennessee Health Sciences Center and Le Bonheur Children's Hospital, Memphis, Tennessee.
authors.forename: Christopher J
authors.initials: CJ
authors.lastname: Knott-Craig
mesh_terms: D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000601:surgery*; D001022:Aortic Valve Insufficiency / Q000175:diagnosis / Q000601:surgery*; D001705:Bioprosthesis / Q000009:adverse effects*; D002648:Child; D017548:Echocardiography, Transesophageal; D005260:Female; D006350:Heart Valve Prosthesis / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008943:Mitral Valve / Q000000981:diagnostic imaging / Q000601:surgery*; D008944:Mitral Valve Insufficiency / Q000175:diagnosis / Q000601:surgery*; D010496:Pericardium / Q000000981:diagnostic imaging / Q000601:surgery*; D011474:Prosthesis Design; D011475:Prosthesis Failure