title: Changing clinical profile and factors associated with liver enzyme abnormalities among HIV-infected persons.
abstract: The spectrum of liver disease among HIV-infected patients is changing. In the era of antiretroviral therapy, opportunistic infections are diminishing and deranged liver function appears to be due usually to drug-induced liver injury, alcohol, non-alcoholic steatohepatitis (NASH) or chronic hepatitis B. To test this hypothesis, 98 HIV-positive patients with deranged liver function were compared with matched HIV-positive patients with normal liver function and likewise matched HIV-negative patients with normal liver function tests.
authors.affiliation: Department of Gastroenterology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India.
authors.forename: Ashok R
authors.initials: AR
authors.lastname: Mohite
authors.affiliation: Department of Gastroenterology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India.
authors.forename: Pravir A
authors.initials: PA
authors.lastname: Gambhire
authors.affiliation: Department of Gastroenterology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India.
authors.forename: Sunil V
authors.initials: SV
authors.lastname: Pawar
authors.affiliation: Department of Gastroenterology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India.
authors.forename: Samit S
authors.initials: SS
authors.lastname: Jain
authors.affiliation: Department of Gastroenterology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India.
authors.forename: Qais Q
authors.initials: QQ
authors.lastname: Contractor
authors.affiliation: Department of Gastroenterology, TN Medical College and BYL Nair Charitable Hospital, Mumbai, India.
authors.forename: Pravin M
authors.initials: PM
authors.lastname: Rathi
mesh_terms: D017088:AIDS-Related Opportunistic Infections / Q000453:epidemiology*; D000328:Adult; D015331:Cohort Studies; D005260:Female; D015658:HIV Infections / Q000453:epidemiology*; D006525:Hepatitis, Viral, Human / Q000453:epidemiology*; D006801:Humans; D007194:India / Q000453:epidemiology; D008099:Liver / Q000201:enzymology*; D008107:Liver Diseases / Q000453:epidemiology*; D008111:Liver Function Tests; D008297:Male; D008875:Middle Aged; D015995:Prevalence; D011446:Prospective Studies
keywords: AIDS; Asia; digestive; epidemiology