title: Minimally Invasive Surgical Technique in Periodontal Regeneration: A Randomized Controlled Clinical Trial Pilot Study.
abstract: The purpose of this study was to compare two minimally invasive surgical techniques (MISTs) for the treatment of periodontal defects: (1) guided tissue regeneration (GTR) using resorbable minimembrane and particulate xenograft (DBBM); and (2) inductive periodontal regeneration (IPR) using enamel matrix derivatives and DBBM. A sample of 20 infrabony periodontal defects in 20 patients were randomly assigned to either the GTR or the IPR group. A follow-up was performed at 12 months postoperative. Significant improvement in clinical parameters was observed in both groups, although no intergroup differences were found. MIST with GTR or IPR demonstrated very good outcomes 1 year after surgery, with no differences between treatment groups.
authors.forename: Carlo
authors.initials: C
authors.lastname: Ghezzi
authors.forename: Luca
authors.initials: L
authors.lastname: Ferrantino
authors.forename: Luigi
authors.initials: L
authors.lastname: Bernardini
authors.forename: Margherita
authors.initials: M
authors.lastname: Lencioni
authors.forename: Silvia
authors.initials: S
authors.lastname: Masiero
mesh_terms: D020341:Absorbable Implants; D003746:Dental Enamel Proteins / Q000627:therapeutic use; D005260:Female; D016557:Guided Tissue Regeneration, Periodontal / Q000379:methods*; D064593:Heterografts; D006801:Humans; D007558:Italy; D008297:Male; D008567:Membranes, Artificial; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures; D010510:Periodontal Diseases / Q000601:surgery*; D010865:Pilot Projects; D016896:Treatment Outcome
chemical_list: D003746:Dental Enamel Proteins; D008567:Membranes, Artificial; C109069:enamel matrix proteins