title: Cost of ventral hernia repair using biologic or synthetic mesh.
abstract: Patients undergoing ventral hernia repair (VHR) with biologic mesh (BioM) have higher hospital costs compared with synthetic mesh (SynM). This study compares 90-d pre- and post-VHR hospital costs (180-d) among BioM and SynM based on infection risk.
  
  
  
  This retrospective National Surgical Quality Improvement Program study matched patient perioperative risk with resource utilization cost for a consecutive series of VHR repairs. Patient infection risks, clinical and financial outcomes were compared in unmatched SynM (n = 303) and BioM (n = 72) groups. Propensity scores were used to match 35 SynM and BioM pairs of cases with similar infection risk for outcomes analysis.
  
  
  
  BioM patients in the unmatched group were older with higher American Society of Anesthesiologists (ASA) and wound classification, and they more frequently underwent open repairs for recurrent hernias. Wound surgical site infections were more frequent in unmatched BioM patients (P = 0.001) as were 180-d costs ($43.8k versus $14.0k, P < 0.001). Propensity matching resulted in 31 clean cases. In these low-risk patients, wound occurrences and readmissions were identical, but 180-d costs remained higher ($31.8k versus $15.5k, P < 0.001). There were no differences in hospital 180-d diagnostic, emergency room, intensive care unit, floor, pharmacy, or therapeutic costs. However, 180-d operating room services and supply costs were higher in the BioM group ($21.1k versus $7.1k, P < 0.001).
  
  
  
  BioM is used more commonly in hernia repairs involving higher wound class and ASA scores and recurrent hernias. Clinical outcomes after low-risk VHRs are similar; SynM utilization in low-risk hernia repairs was more cost-effective.
authors.affiliation: Department of Surgery, University of Kentucky, Lexington, Kentucky. Electronic address: crystal.totten@uky.edu.
authors.forename: Crystal F
authors.initials: CF
authors.lastname: Totten
authors.affiliation: Department of Surgery, University of Kentucky, Lexington, Kentucky.
authors.forename: Daniel L
authors.initials: DL
authors.lastname: Davenport
authors.affiliation: College of Medicine, University of Kentucky, Lexington, Kentucky.
authors.forename: Nicholas D
authors.initials: ND
authors.lastname: Ward
authors.affiliation: Department of Surgery, University of Kentucky, Lexington, Kentucky.
authors.forename: J Scott
authors.initials: JS
authors.lastname: Roth
mesh_terms: D000328:Adult; D000368:Aged; D003362:Cost-Benefit Analysis; D005260:Female; D005500:Follow-Up Studies; D006555:Hernia, Ventral / Q000191:economics / Q000601:surgery*; D059685:Herniorrhaphy / Q000191:economics / Q000295:instrumentation* / Q000379:methods; D017721:Hospital Costs / Q000706:statistics & numerical data*; D006801:Humans; D007629:Kentucky; D008297:Male; D008875:Middle Aged; D057216:Propensity Score; D012189:Retrospective Studies; D018570:Risk Assessment; D012307:Risk Factors; D013526:Surgical Mesh / Q000191:economics*; D013530:Surgical Wound Infection / Q000191:economics / Q000209:etiology; D016896:Treatment Outcome
keywords: Biologic; Cost; Hernia; Mesh; Outcomes; Synthetic