title: A Highly Sensitive Molecular Detection Platform for Robust and Facile Diagnosis of Middle East Respiratory Syndrome (MERS) Corona Virus.
abstract: Trail polymerization enables a significant enhancement of the DhITACT system. DhITACT-Trail (DNA hydrogel formation by isothermal amplification of complementary targets trail polymerization) offers a robust diagnosis of target RNA strands in pseudo-serum specimen. This system requires minimum liquid handling as compared to conventional analysis. In addition, a definitive diagnostic result can be achieved within 30 min by an optical detection.
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Il Young
authors.initials: IY
authors.lastname: Jung
authors.affiliation: Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea.
authors.forename: Jae Bem
authors.initials: JB
authors.lastname: You
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Bo Ram
authors.initials: BR
authors.lastname: Choi
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Ji Su
authors.initials: JS
authors.lastname: Kim
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Hyun Kyung
authors.initials: HK
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Bora
authors.initials: B
authors.lastname: Jang
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Han Saem
authors.initials: HS
authors.lastname: Jeong
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea.
authors.forename: Kyuri
authors.initials: K
authors.lastname: Lee
authors.affiliation: Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. sgim@kaist.ac.kr.|KAIST Institute for Nano Century, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, 34141, Republic of Korea. sgim@kaist.ac.kr.
authors.forename: Sung Gap
authors.initials: SG
authors.lastname: Im
authors.affiliation: College of Pharmacy, Graduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul, 120-750, Republic of Korea. hyukjin@ewha.ac.kr.
authors.forename: Hyukjin
authors.initials: H
authors.lastname: Lee
mesh_terms: D015374:Biosensing Techniques; D018352:Coronavirus Infections / Q000175:diagnosis*; D006801:Humans; D065207:Middle East Respiratory Syndrome Coronavirus; D012680:Sensitivity and Specificity