title: Direct oral anticoagulants for venous thromboembolism treatment and prophylaxis.
abstract: Direct oral anticoagulants are a popular option for prevention and treatment of venous thromboembolism. However, they possess significantly different pharmacologic properties from warfarin. This article reviews approved direct oral anticoagulants, their indications, pharmacologic properties, monitoring, and reversal strategies.
authors.affiliation: Brian K. Yorkgitis practices in the Division of Acute Care Surgery at the University of Florida-Jacksonville. The author has disclosed no potential conflicts of interest, financial or otherwise.
authors.forename: Brian K
authors.initials: BK
authors.lastname: Yorkgitis
mesh_terms: D000284:Administration, Oral; D000925:Anticoagulants / Q000627:therapeutic use*; D006801:Humans; D054556:Venous Thromboembolism / Q000188:drug therapy*; D014859:Warfarin / Q000627:therapeutic use
chemical_list: D000925:Anticoagulants; D014859:Warfarin