title: RAACFDb: Rheumatoid arthritis ayurvedic classical formulations database.
abstract: BACKGROUND
  In the past years, the treatment of rheumatoid arthritis (RA) has undergone remarkable changes in all therapeutic modes. The present newfangled care in clinical research is to determine and to pick a new track for better treatment options for RA. Recent ethnopharmacological investigations revealed that traditional herbal remedies are the most preferred modality of complementary and alternative medicine (CAM). However, several ayurvedic modes of treatments and formulations for RA are not much studied and documented from Indian traditional system of medicine. Therefore, this directed us to develop an integrated database, RAACFDb (acronym: Rheumatoid Arthritis Ayurvedic Classical Formulations Database) by consolidating data from the repository of Vedic Samhita - The Ayurveda to retrieve the available formulations information easily.
  
  
  METHODS
  Literature data was gathered using several search engines and from ayurvedic practitioners for loading information in the database. In order to represent the collected information about classical ayurvedic formulations, an integrated database is constructed and implemented on a MySQL and PHP back-end.
  
  
  RESULTS
  The database is supported by describing all the ayurvedic classical formulations for the treatment rheumatoid arthritis. It includes composition, usage, plant parts used, active ingredients present in the composition and their structures.
  
  
  CONCLUSIONS
  The prime objective is to locate ayurvedic formulations proven to be quite successful and highly effective among the patients with reduced side effects. The database (freely available at www.beta.vit.ac.in/raacfdb/index.html) hopefully enables easy access for clinical researchers and students to discover novel leads with reduced side effects.
authors.affiliation: Department of Integrative Biology, School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, India.
authors.forename: A M
authors.initials: AM
authors.lastname: Mohamed Thoufic Ali
authors.affiliation: Department of Biotechnology, School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, India.
authors.forename: Aakash
authors.initials: A
authors.lastname: Agrawal
authors.affiliation: Department of Biotechnology, School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, India.
authors.forename: S
authors.initials: S
authors.lastname: Sajitha Lulu
authors.affiliation: Department of Biotechnology, School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, India.
authors.forename: A
authors.initials: A
authors.lastname: Mohana Priya
authors.affiliation: Department of Integrative Biology, School of Bio Sciences and Technology, VIT University, Vellore, Tamil Nadu, India. Electronic address: svino@vit.ac.in.
authors.forename: S
authors.initials: S
authors.lastname: Vino
mesh_terms: D018501:Antirheumatic Agents / Q000627:therapeutic use*; D001172:Arthritis, Rheumatoid / Q000188:drug therapy*; D002626:Chemistry, Pharmaceutical / Q000379:methods; D000529:Complementary Therapies / Q000379:methods; D016208:Databases, Factual; D020834:Ethnopharmacology / Q000379:methods; D006801:Humans; D008515:Medicine, Ayurvedic; D008517:Phytotherapy / Q000379:methods
chemical_list: D018501:Antirheumatic Agents
keywords: Ayurveda database; Ayurvedic formulations; Rheumatoid arthritis; Vedic samhita