title: Trajectories of Depressive Symptomatology in Rural Memory Clinic Patients between Baseline Diagnosis and 1-Year Follow-Up.
abstract: OBJECTIVE
  To investigate the prevalence and trajectories of depressive symptomatology at 1-year follow-up, and the severity of depressive symptoms, by dementia diagnostic group, as well as to determine the predictors of depressive symptomatology at 1-year follow-up.
  
  
  METHODS
  In rural and remote patients of an interdisciplinary memory clinic between 2004 and 2014, 144 patients diagnosed with no cognitive impairment (NCI), mild cognitive impairment, dementia due to Alzheimer's disease (AD), or non-AD dementia completed the Center for Epidemiologic Studies of Depression Scale to assess depressive symptomatology at both time points.
  
  
  RESULTS
  Among patients with data at both time points, persistence of depressive symptomatology at follow-up occurred in 22.2%, remission in 17.4%, incidence in 13.2%, and absence in 47.2%. The prevalence of depressive symptomatology at baseline and persistence at follow-up were significantly greater in the NCI group than in the other diagnostic groups, but there were no differences in severity. Depressive symptomatology at follow-up was independently associated with depressive symptomatology, lower independence in activities of daily living, and lower self-rating of memory at baseline, as well as with decreased independence in activities of daily living between time points.
  
  
  CONCLUSIONS
  Future studies should further examine short-term postdiagnostic trajectories in depressive symptomatology in multiple dementia diagnostic groups to inform prognoses and treatment decisions.
authors.affiliation: Canadian Centre for Health and Safety in Agriculture, College of Medicine, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Julie G
authors.initials: JG
authors.lastname: Kosteniuk
authors.affiliation: Canadian Centre for Health and Safety in Agriculture, College of Medicine, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Debra G
authors.initials: DG
authors.lastname: Morgan
authors.affiliation: Department of Psychology, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Megan E
authors.initials: ME
authors.lastname: O'Connell
authors.affiliation: Division of Neurology, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Andrew
authors.initials: A
authors.lastname: Kirk
authors.affiliation: Department of Psychology, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Margaret
authors.initials: M
authors.lastname: Crossley
authors.affiliation: College of Nursing, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Norma J
authors.initials: NJ
authors.lastname: Stewart
authors.affiliation: Canadian Centre for Health and Safety in Agriculture, College of Medicine, University of Saskatchewan, Saskatoon, Sask., Canada.
authors.forename: Chandima P
authors.initials: CP
authors.lastname: Karunanayake
keywords: Alzheimer's disease; Dementia; Depression; Depressive symptoms; Memory clinic; Mild cognitive impairment; Rural population