title: Research Progress of Natural Product Gentiopicroside - a Secoiridoid Compound.
abstract: Gentiopicroside is a secoiridoid compound isolated from Gentiana lutea which is called Qin Jiao in Chinese. It is one of the most common herbal medicines used in China. In this article, we review the pharmacological and biological activity (antiviral, anti-inflammatory, analgesia, antihepatotoxic and choleretic), as well as biotransformation of the gentiopicroside. In addition, attempt towards the total synthesis of gentiopicroside is also presented.
authors.forename: Shaoping
authors.initials: S
authors.lastname: Wu
authors.forename: Yaoyao
authors.initials: Y
authors.lastname: Ning
authors.forename: Yingyong
authors.initials: Y
authors.lastname: Zhao
authors.forename: Wenji
authors.initials: W
authors.lastname: Sun
authors.forename: Serge
authors.initials: S
authors.lastname: Thorimbert
authors.forename: Luc
authors.initials: L
authors.lastname: Dechoux
authors.forename: Matthieu
authors.initials: M
authors.lastname: Sollogoub
authors.affiliation: Sorbonne Universités, UPMC Univ Paris 06, CNRS UMR 8232, 4 place Jussieu, 75005 Paris, France.
authors.forename: Yongmin
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D000700:Analgesics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000818:Animals; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D000998:Antiviral Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D001688:Biological Products / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D001711:Biotransformation; D002756:Cholagogues and Choleretics / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D030012:Gentiana / Q000737:chemistry; D006801:Humans; D057888:Iridoid Glucosides / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D015394:Molecular Structure; D020011:Protective Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000700:Analgesics; D000894:Anti-Inflammatory Agents, Non-Steroidal; D000998:Antiviral Agents; D001688:Biological Products; D002756:Cholagogues and Choleretics; D057888:Iridoid Glucosides; D020011:Protective Agents; C012997:gentiopicroside