title: Multicriteria decision analysis and core values for enhancing vaccine-related decision-making.
abstract: Vaccines have the potential to transform the health of all individuals and to reduce the health inequality between rich and poor countries. However, to achieve these goals, it is no longer sufficient to prioritize vaccine development using cost-effectiveness as the sole indicator. During a symposium entitled "Mission Grand Convergence-The Role of Vaccines," held in Siena, Italy, in July 2015, key stakeholders agreed that the prioritization of vaccine development and deployment must use multicriteria decision-making based on the following core concepts: (i) mortality and severity of the disease, (ii) vaccine safety considerations, and (iii) economic evaluation that captures the full benefits of vaccination.
authors.affiliation: GSK Vaccines, Via Fiorentina 1, 53100 Siena, Italy.
authors.forename: Michèle A
authors.initials: MA
authors.lastname: Barocchi
authors.affiliation: Center for Global Health, Cincinnati Children's Hospital, Cincinnati, OH 45229, USA.
authors.forename: Steve
authors.initials: S
authors.lastname: Black
authors.affiliation: GSK Vaccines, Via Fiorentina 1, 53100 Siena, Italy. rino.r.rappuoli@gsk.com.
authors.forename: Rino
authors.initials: R
authors.lastname: Rappuoli
mesh_terms: D003362:Cost-Benefit Analysis; D003657:Decision Making; D003661:Decision Support Techniques; D054624:Health Status Disparities; D006801:Humans; D014612:Vaccines / Q000009:adverse effects / Q000191:economics*
chemical_list: D014612:Vaccines