title: Near Full-Length Genome Identification of a Novel HIV-1 Recombinant Form (CRF01_AE/CRF07_BC) in Zhejiang, China.
abstract: CRF01_AE and CRF07_BC are the two major circulating recombinant forms (CRFs) in China. Furthermore, many kinds of unique recombinant forms (URFs) between CRF01_AE and CRF07_BC were recently identified in China. Here we detected a novel recombinant of CRF07_BC/CRF01_AE, whose genome structure is distinctly different from other URFs reported before. The phylogenetic analysis of the near full-length sequence of 15zj032 reveals that three regions of CRF01_AE insert into the CRF07_BC backbone. Recently, the continued emergence of novel URFs implies that super infections of different subtypes of HIV-1 are common in China and should be given enough importance.
authors.affiliation: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, China .
authors.forename: Xiaorong
authors.initials: X
authors.lastname: Peng
authors.affiliation: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, China .
authors.forename: Xu
authors.initials: X
authors.lastname: Li-Jun
authors.affiliation: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, China .
authors.forename: Tiansheng
authors.initials: T
authors.lastname: Xie
authors.affiliation: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, China .
authors.forename: Fumin
authors.initials: F
authors.lastname: Liu
authors.affiliation: State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, the First Affiliated Hospital, School of Medicine, Zhejiang University , Hangzhou, China .
authors.forename: Nanping
authors.initials: N
authors.lastname: Wu
mesh_terms: D002681:China / Q000453:epidemiology; D019143:Evolution, Molecular; D016679:Genome, Viral; D005838:Genotype; D015658:HIV Infections / Q000453:epidemiology / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D006801:Humans; D008297:Male; D017720:Molecular Epidemiology; D010802:Phylogeny; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA