title: Metastasising pleomorphic adenoma of the submandibular salivary gland presenting with spinal cord compression: case report and review of cases with CNS involvement.
abstract: We present a very rare case of a metastasising pleomorphic adenoma with spinal cord compression and review the small handful of cases with central nervous system (CNS) involvement in the literature. This case is unusual as most other reported cases are preceded by local recurrences; also, there is only one previous case of an MPA presenting with spinal cord compression. Metastasising pleomorphic adenoma is a rare malignant salivary gland tumour which, despite "benign" histological appearances produces secondary deposits in distant sites.
authors.affiliation: a Department of Medicine , St George's University of London , London , UK.
authors.forename: James
authors.initials: J
authors.lastname: Knight
authors.affiliation: b Department of Cellular Pathology , Atkinson Morley Wing, St George's Hospital , London , UK.
authors.forename: Leslie R
authors.initials: LR
authors.lastname: Bridges
authors.affiliation: c Department of Neurosurgery , Atkinson Morley Wing, St George's Hospital , London , UK.
authors.forename: Pawanjit S
authors.initials: PS
authors.lastname: Minhas
authors.affiliation: c Department of Neurosurgery , Atkinson Morley Wing, St George's Hospital , London , UK.
authors.forename: George
authors.initials: G
authors.lastname: Eralil
mesh_terms: D008949:Adenoma, Pleomorphic / Q000150:complications / Q000601:surgery*; D000368:Aged; D019299:Decompression, Surgical; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D009362:Neoplasm Metastasis; D019635:Neurosurgical Procedures / Q000379:methods; D013117:Spinal Cord Compression / Q000209:etiology* / Q000601:surgery*; D013120:Spinal Cord Neoplasms / Q000150:complications / Q000556:secondary* / Q000601:surgery*; D013365:Submandibular Gland Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed
keywords: Case report; cord compression; pleomorphic adenoma; spine