title: Applying orthodontic tooth extrusion in a patient treated with bisphosphonate and irradiation: a case report.
abstract: Bisphosphonates and irradiation are useful medical treatments, but can often cause oral complications such as medication-related oral necrosis of the jaw (MRONJ) and osteoradionecrosis (ORN) during oral surgery, including tooth extraction. Therefore, we should take all risks into consideration carefully before choosing dental treatment for patients with a medical history of such therapies. A 55-year-old woman who underwent cord blood transplantation to treat extranodal natural killer T (NK/T) cell lymphoma (nasal type IVB) had a medical history of bisphosphonate and irradiation treatments. We treated her residual tooth root by applying orthodontic extrusion to avoid extraction and successfully restored the tooth. Application of an orthodontic tooth extrusion technique for conservative treatment of a residual tooth is a useful means of avoiding MRONJ or ORN in patients who have a medical history of bisphosphonate and irradiation treatments.
authors.affiliation: Section of General Dentistry, Department of General Dentistry, Fukuoka, Japan.|Special Patient Oral Care Unit, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Hiromitsu
authors.initials: H
authors.lastname: Morita
authors.affiliation: Special Patient Oral Care Unit, Kyushu University Hospital, Fukuoka, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Imai
authors.affiliation: Section of General Dentistry, Department of General Dentistry, Fukuoka, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Yoneda
authors.affiliation: Section of General Dentistry, Department of General Dentistry, Fukuoka, Japan.
authors.forename: Takao
authors.initials: T
authors.lastname: Hirofuji
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D003131:Combined Modality Therapy; D036101:Cord Blood Stem Cell Transplantation; D004164:Diphosphonates / Q000627:therapeutic use; D005260:Female; D006801:Humans; D016399:Lymphoma, T-Cell / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D008875:Middle Aged; D009669:Nose Neoplasms / Q000188:drug therapy / Q000532:radiotherapy / Q000628:therapy*; D050793:Orthodontic Extrusion
chemical_list: D004164:Diphosphonates
keywords: bisphosphonate; cord blood transplantation; irradiation; tooth extrusion