title: Supramolecular Recognition of Amino Acids by Twisted Cucurbit[14]uril.
abstract: Binding interactions between twisted cucurbit[14]uril (tQ[14]) and twenty standard amino acids (AAs) have been investigated by NMR spectroscopy and isothermal titration calorimetry (ITC) in aqueous HCl solutions and in DMSO. The results showed that tQ[14] displays clear binding affinity for AAs with a positively charged side chain or containing an aromatic ring, but weaker binding affinity for AAs with hydrophobic or polar side chains, with the binding mode depending on the type of side chain present in the AAs.
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang, 550025, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang, 550025, China.
authors.forename: Yun-Yun
authors.initials: YY
authors.lastname: Xi
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang, 550025, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Li
authors.affiliation: The Engineering and Research Center for Southwest Bio-Pharmaceutical resources of, National Education Ministry of China, Guizhou University, Guiyang, 550025, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Tang
authors.affiliation: State Key Laboratory of Quality Research in Chinese Medicine, Institute of Chinese Medical Sciences, University of Macau, Taipa, Macau SAR.
authors.forename: Ruibing
authors.initials: R
authors.lastname: Wang
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang, 550025, China. yinghung128@163.com.|The Engineering and Research Center for Southwest Bio-Pharmaceutical resources of, National Education Ministry of China, Guizhou University, Guiyang, 550025, China. yinghung128@163.com.
authors.forename: Ying
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang, 550025, China.
authors.forename: Zhu
authors.initials: Z
authors.lastname: Tao
authors.affiliation: Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang, 550025, China.
authors.forename: Sai-Feng
authors.initials: SF
authors.lastname: Xue
authors.affiliation: School of Chemistry, The University of Sydney, NSW, 2006, Australia. len.lindoy@sydney.edu.au.
authors.forename: Leonard F
authors.initials: LF
authors.lastname: Lindoy
authors.affiliation: CSIRO Manufacturing, PO Box 218, Lindfield, NSW, 2070, Australia. gang.wei@csiro.au.
authors.forename: Gang
authors.initials: G
authors.lastname: Wei
mesh_terms: D000596:Amino Acids / Q000032:analysis* / Q000737:chemistry*; D001952:Bridged-Ring Compounds / Q000737:chemistry*; D002151:Calorimetry; D007093:Imidazoles / Q000737:chemistry*; D046911:Macromolecular Substances / Q000737:chemistry; D009682:Magnetic Resonance Spectroscopy; D008958:Models, Molecular
chemical_list: D000596:Amino Acids; D001952:Bridged-Ring Compounds; D007093:Imidazoles; D046911:Macromolecular Substances
keywords: amino acids; host-guest chemistry; side chains; supramolecular recognition; twisted cucurbit[14]uril