title: Obsessive compulsive personality disorder in Progressive Supranuclear Palsy, Multiple System Atrophy and Essential Tremor.
abstract: aim of the study was to evaluate the presence of the Obsessive Compulsive Personality Disorder (OCPeD) in Multiple System Atrophy (MSA), Progressive Supranuclear Palsy (PSP) and Essential Tremor (ET) and in a group of healthy subjects.
  
  
  
  patients affected by MSA, PSP and ET diagnosed according to currently accepted diagnostic criteria and a group of healthy controls were enrolled in the study. Patients with cognitive impairment were excluded from the study. The Structured Clinical Interview for Personality Disorders-II (SCID-II) has been performed to evaluate the presence of personality disorders (PeDs). The diagnosis of OCPeD was confirmed by a psychiatric interview.
  
  
  
  fifteen MSA patients (8 men and 7 women; aged 62.9 ± 7.6 years), 14 PSP patients (8 men and 6 women; aged 69.8 ± 4.4 years), 16 ET patients (10 men and 6 women; aged 70.4 ± 6.4 years) and 20 healthy subjects (10 men and 10 women; aged 65.5 ± 6.0 years) were enrolled. OCPeD was recorded in 5 (35.7%) PSP patients, 2 (13.3%) MSA patients, 2 (12.5%) ET patient and 2 (10%) controls.
  
  
  
  a low frequency of OCPeD, close to those recorded in healthy subjects, was recorded in both MSA and ET patients. Conversely an higher frequency of OCPeD, similar to PD was found among PSP patients, supporting the possibility of an impairment of common basal ganglia network possibly involving the orbito-frontal circuits.
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Nicoletti
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Luca
authors.affiliation: Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Luca
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Donzuso
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Mostile
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Raciti
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Contrafatto
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: V
authors.initials: V
authors.lastname: Dibilio
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: G
authors.initials: G
authors.lastname: Sciacca
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: C E
authors.initials: CE
authors.lastname: Cicero
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Vasta
authors.affiliation: Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Petralia
authors.affiliation: Section of Neurosciences, Department GF Ingrassia, University of Catania, Catania, Italy. Electronic address: m.zappia@unict.it.
authors.forename: M
authors.initials: M
authors.lastname: Zappia
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003193:Compulsive Personality Disorder / Q000175:diagnosis* / Q000503:physiopathology; D003937:Diagnosis, Differential; D020329:Essential Tremor / Q000175:diagnosis* / Q000503:physiopathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D019578:Multiple System Atrophy / Q000175:diagnosis* / Q000503:physiopathology; D010300:Parkinson Disease / Q000175:diagnosis / Q000503:physiopathology*; D013494:Supranuclear Palsy, Progressive / Q000175:diagnosis* / Q000503:physiopathology
keywords: Essential tremor; Obsessive compulsive personality disorders; Parkinsonism; Personality disorders