title: Post aortic dissection: Gap between activity recommendation and real life patients aerobic capacities.
abstract: BACKGROUND
  Regular exercise at a safe level, i.e. 3-5 metabolic equivalents, is recommended to improve blood pressure control and quality of life even after aortic dissection, although aerobic exercise capacities in these patients are unexplored yet.
  
  
  METHODS
  We prospectively collected data from 105 patients with a history of post aortic dissection referred for a cardiopulmonary exercise testing (CPX) aiming to guide exercise rehabilitation.
  
  
  RESULTS
  The population was composed of 76% of male, with a mean age of 57.9±12.4years. There were an equal distribution between the two type of dissection (47% of type A and 53% of type B aortic dissection). No cardiac event occurred during or after CPX. One third of patients have normal aerobic exercise capacity defined as peak oxygen uptake upper than 85% of their predicted capacity. Mean oxygen uptake peak was quite low 19.2±5.2ml/kg/min (5.5±1.5 metabolic equivalents). Aerobic capacity was limited by cardiac chronotropic incompetence in 42% or peripheral deconditioning in 45%. Blood pressure remained in an acceptable range during the exercise. Systolic and diastolic blood pressures were respectively 151±20 and 77±13mmHg at first ventilatory threshold.
  
  
  CONCLUSIONS
  CPX is a safe exploration in patients with post aortic dissection syndrome. Given the fact that most of these patients are faced with significant alteration of aerobic capacities, the recommended daily practice of moderate exercise at 3-5 METS should be adapted and personalized to each patient thanks to CPX.
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France. Electronic address: Pascal.DELSART@CHRU-LILLE.fr.
authors.forename: Pascal
authors.initials: P
authors.lastname: Delsart
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: Pauline
authors.initials: P
authors.lastname: Maldonado-Kauffmann
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: Mathieu
authors.initials: M
authors.lastname: Bic
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: Fanny
authors.initials: F
authors.lastname: Boudghene-Stambouli
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Jonathan
authors.initials: J
authors.lastname: Sobocinski
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Francis
authors.initials: F
authors.lastname: Juthier
authors.affiliation: CHU Lille, Echocardiography department, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: Olivia
authors.initials: O
authors.lastname: Domanski
authors.affiliation: CHU Lille, Echocardiography department, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Augustin
authors.initials: A
authors.lastname: Coisne
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: Richard
authors.initials: R
authors.lastname: Azzaoui
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Natacha
authors.initials: N
authors.lastname: Rousse
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: George
authors.initials: G
authors.lastname: Fayad
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Modine
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Stephan
authors.initials: S
authors.lastname: Haulon
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Andre
authors.initials: A
authors.lastname: Vincentelli
authors.affiliation: CHU Lille, Cardiology hospital, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: Claire
authors.initials: C
authors.lastname: Mounier-Vehier
authors.affiliation: CHU Lille, Echocardiography department, Bd Pr Leclercq, F-59000 Lille, France; University of Lille, CHU Lille, F-59000 Lille, France.
authors.forename: David
authors.initials: D
authors.lastname: Montaigne
mesh_terms: D000328:Adult; D000368:Aged; D015308:Anaerobic Threshold / Q000502:physiology; D000784:Aortic Dissection / Q000503:physiopathology* / Q000534:rehabilitation*; D001014:Aortic Aneurysm / Q000503:physiopathology* / Q000534:rehabilitation*; D005080:Exercise Test / Q000379:methods*; D017079:Exercise Tolerance / Q000502:physiology*; D005260:Female; D005500:Follow-Up Studies; D006306:Health Surveys / Q000379:methods; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
keywords: Activity recommendation; Aortic dissection; Exercise capacity