title: [A woman with iris heterochromia].
abstract: A 20-year-old woman with congenital iris heterochromia presented with loss of vision of her right eye. We made de diagnosis of a large 'uvea melanoma' and enucleated the eye. Pathological examination showed an underlying oculodermal melanocytosis (ODM). The life-time risk of uveal melanoma in the general population is 0.7:100,000, but 1:400 in patients with ODM. Therefore, annual fundoscopy is recommended in these patients.
authors.affiliation: Leids Universitair Medisch Centrum, afd. Oogheelkunde, Leiden.
authors.forename: I L
authors.initials: IL
authors.lastname: Birker
authors.forename: L S T M
authors.initials: LS
authors.lastname: Boons
authors.forename: G P M
authors.initials: GP
authors.lastname: Luyten
mesh_terms: D005124:Eye Abnormalities / Q000175:diagnosis*; D005260:Female; D006801:Humans; D007498:Iris / Q000473:pathology*; D015811:Iris Neoplasms / Q000150:complications / Q000175:diagnosis*; D008545:Melanoma / Q000150:complications / Q000175:diagnosis*; D014604:Uveal Neoplasms / Q000150:complications / Q000175:diagnosis*; D055815:Young Adult; D000098943:Uveal Melanoma