title: Nutritional factors and metabolic variables in relation to the risk of coronary heart disease: A case control study in Armenian adults.
abstract: BACKGROUND
  Dietary factors can affect the coronary heart disease (CHD). Results of previous studies on the association between the diet and CHD are not consistent in different countries. There were no data on this association in Armenia.
  
  
  OBJECTIVE
  Aims of this case-control study were to evaluate the association between nutritional factors and CHD among Armenians in Yerevan.
  
  
  METHODS
  During 2010 and 2011, we randomly selected 320 CHD patients with a diagnosis of CHD less than 6 months and 320 subjects without CHD (≥30years old) from the hospitals and polyclinics in Yerevan. Dietary intakes with 135 food items over the previous 12 months were evaluated using a semi-quantitative food frequency questionnaire.
  
  
  RESULTS
  After adjusting for some CHD risk factors higher intakes of polyunsaturated fatty acids (PUFA) and monounsaturated fatty acids (MUFA) were associated with a reduced risk of CHD, while this association was not witnessed for saturated fatty acids (SFA). In addition, findings indicated an inverse relation between vitamins (E, B6 and B12, folic acid) and fiber with CHD. In this population, smoking, hypertension, and metabolic syndrome (MetS) were significantly more common among patients with CHD.
  
  
  CONCLUSIONS
  The intake of vitamins E, B6 and B12, folic acid, PUFA, MUFA and fiber appeared to be predictors of CHD, independently of other risk factors.
authors.affiliation: Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Ezatollah
authors.initials: E
authors.lastname: Fazeli Moghadam
authors.affiliation: DSC Public Health Department, Yerevan State Medical University, Yerevan, Armenia.
authors.forename: Artashes
authors.initials: A
authors.lastname: Tadevosyan
authors.affiliation: Nutrition Department, Faculty of Health and Nutrition, Lorestan University of Medical Sciences, Khorramabad, Iran.
authors.forename: Ebrahim
authors.initials: E
authors.lastname: Fallahi
authors.affiliation: Imam Hospital of Borujerd, Lorestan University of Medical Sciences and Health Services, Borujerd, Iran. Electronic address: goodarzi121@yahoo.com.
authors.forename: Reza
authors.initials: R
authors.lastname: Goodarzi
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D001136:Armenia / Q000453:epidemiology; D016022:Case-Control Studies; D003324:Coronary Artery Disease / Q000453:epidemiology / Q000209:etiology; D004032:Diet / Q000009:adverse effects; D004041:Dietary Fats / Q000009:adverse effects; D019587:Dietary Supplements / Q000009:adverse effects; D005492:Folic Acid / Q000009:adverse effects; D005500:Follow-Up Studies; D015994:Incidence; D024821:Metabolic Syndrome / Q000150:complications; D009752:Nutritional Status; D011379:Prognosis; D012307:Risk Factors
chemical_list: D004041:Dietary Fats; D005492:Folic Acid
keywords: Armenia; Coronary heart disease; Dietary factors; Metabolic syndrome; Vitamins