title: RETRACTED: Possible involvement of the HMGB1/RAGE signaling mechanism in the induction of central post-stroke pain induced by acute global cerebral ischemia.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal).
  
  This article has been retracted at the request of the Authors following an investigation into data manipulation (Figures 2A,B and 5) by an Investigation Committee at Kobe Gakuin University.
  
  Namely:
  
  Figures 2A and 2B - numerical disagreement (numbers removed) was found in some parts between the raw data and the article data, hence the significant difference illustrated in the published article was not obtained.
  
  Figure 5 - multiple numbers of the original raw data were changed, hence significant difference the significant difference illustrated in the published article was not obtained.
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
authors.forename: Shinichi
authors.initials: S
authors.lastname: Harada
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan.
authors.forename: Wataru
authors.initials: W
authors.lastname: Matsuura
authors.affiliation: Department of Pharmacology, Graduate School of Medicine, Dentistry and Pharmacological Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.
authors.forename: Keyue
authors.initials: K
authors.lastname: Liu
authors.affiliation: Department of Pharmacology, Graduate School of Medicine, Dentistry and Pharmacological Sciences, Okayama University, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Nishibori
authors.affiliation: Department of Clinical Pharmacy, School of Pharmaceutical Sciences, Kobe Gakuin University, 1-1-3 Minatojima, Chuo-ku, Kobe 650-8586, Japan. Electronic address: stoku@pharm.kobegakuin.ac.jp.
authors.forename: Shogo
authors.initials: S
authors.lastname: Tokuyama
mesh_terms: D000818:Animals; D021461:Animals, Outbred Strains; D000911:Antibodies, Monoclonal / Q000008:administration & dosage; D002545:Brain Ischemia / Q000150:complications / Q000378:metabolism*; D048049:Extracellular Signal-Regulated MAP Kinases / Q000378:metabolism; D024243:HMGB1 Protein / Q000276:immunology / Q000378:metabolism*; D006930:Hyperalgesia / Q000378:metabolism; D007276:Injections, Intraventricular; D008297:Male; D051379:Mice; D010146:Pain / Q000209:etiology / Q000378:metabolism*; D010766:Phosphorylation; D000067759:Receptor for Advanced Glycation End Products / Q000378:metabolism*; D012584:Sciatic Nerve / Q000378:metabolism*; D015398:Signal Transduction; D013116:Spinal Cord / Q000378:metabolism*; D020521:Stroke / Q000150:complications / Q000378:metabolism*
chemical_list: C000593873:Ager protein, mouse; D000911:Antibodies, Monoclonal; D024243:HMGB1 Protein; C582808:HMGB1 protein, mouse; D000067759:Receptor for Advanced Glycation End Products; D048049:Extracellular Signal-Regulated MAP Kinases
keywords: Central post-stroke pain; Cerebral ischemia; High mobility group box-1; Receptor for advanced glycation end products