title: Developing the Thai Siriraj Psoriatic Arthritis Screening Tool and validating the Thai Psoriasis Epidemiology Screening Tool and the Early Arthritis for Psoriatic Patients questionnaire.
abstract: To validate the Thai language version of the Psoriasis Epidemiology Screening Tool (PEST) and the Early Arthritis for Psoriatic Patients Questionnaire (EARP), as well as also to develop a new tool for screening psoriatic arthritis (PsA) among psoriasis (Ps) patients. This was a cross-sectional study. Ps patients visiting the psoriasis clinic at Siriraj Hospital were recruited. They completed the EARP and PEST. Full musculoskeletal history, examination, and radiography were evaluated. PsA was diagnosed by a rheumatologist's evaluation and fulfillment of the classification criteria for psoriatic arthritis. Receiver operator characteristic (ROC) curves, sensitivity, and specificity were used to evaluate the performances of the tools. The Siriraj Psoriatic Arthritis Screening Tool (SiPAT) contained questions most relevant to peripheral arthritis, axial inflammation, and enthesitis, selected from multivariate analysis. Of a total of 159 patients, the prevalence of PsA was 78.6 %. The ROC curve analyses of Thai EARP, PEST, and SiPAT were 0.90 (95 % CI 0.84, 0.96), 0.85 (0.78, 0.92), and 0.89 (0.83, 0.95), respectively. The sensitivities of SiPAT, Thai EARP, and PEST were 91.0, 83.0, and 72.0 %, respectively, while the specificities were 69.0, 79.3, and 89.7 %, respectively. All screening questionnaires showed good diagnostic performances. SiPAT could be considered as a screening tool with its desirable properties: higher sensitivity and taking less time. Thai PEST and EARP could possibly be sequentially administered for people with a positive test from SiPAT to reduce the number of false positives.
authors.affiliation: Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Rd., 8th Floor Asdang Building, Bangkoknoi, Bangkok, 10700, Thailand. praveena.chi@mahidol.ac.th.
authors.forename: Praveena
authors.identifier: http://orcid.org/0000-0002-4253-9229
authors.initials: P
authors.lastname: Chiowchanwisawakit
authors.affiliation: Office of Research and Development, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Luksame
authors.initials: L
authors.lastname: Wattanamongkolsil
authors.affiliation: Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Rd., 8th Floor Asdang Building, Bangkoknoi, Bangkok, 10700, Thailand.
authors.forename: Varalak
authors.initials: V
authors.lastname: Srinonprasert
authors.affiliation: Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Rd., 8th Floor Asdang Building, Bangkoknoi, Bangkok, 10700, Thailand.
authors.forename: Chonachan
authors.initials: C
authors.lastname: Petcharat
authors.affiliation: Department of Radiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.
authors.forename: Palanan
authors.initials: P
authors.lastname: Siriwanarangsun
authors.affiliation: Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Wanglang Rd., 8th Floor Asdang Building, Bangkoknoi, Bangkok, 10700, Thailand.
authors.forename: Wanruchada
authors.initials: W
authors.lastname: Katchamart
mesh_terms: D000328:Adult; D015535:Arthritis, Psoriatic / Q000175:diagnosis* / Q000453:epidemiology; D003430:Cross-Sectional Studies; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening; D008875:Middle Aged; D015995:Prevalence; D011565:Psoriasis / Q000453:epidemiology; D012680:Sensitivity and Specificity; D011795:Surveys and Questionnaires; D013785:Thailand; D014177:Translations
keywords: Screening psoriatic arthritis; Thai Psoriatic Arthritis Screening Tool; The Early Arthritis for Psoriatic Patients questionnaire; The Psoriasis Epidemiology Screening Tool