title: [Epigenetic Regulation by Androgen Receptor and Possible Function in Bone Metabolism].
abstract: Epigenetic regulation underlying AR(Androgen receptor)mediated transcription is important component to understand pathophysiology of osteoporosis in men. In this commentary, it is reported recent findings related to epigenetic landscape governed by AR and its cofactors including lysine-specific demethylase 1 (LSD1), and possible implication for bone metabolism.
authors.affiliation: Division of Integrative Pathophysiology, Proteo-Science Center, Department of Pathophysiology, Graduate School of Medicine, Division of Experimental Animal Research, Advanced Research Support Center, Ehime University, Japan.
authors.forename: Yuuki
authors.initials: Y
authors.lastname: Imai
mesh_terms: D001842:Bone and Bones / Q000378:metabolism*; D044127:Epigenesis, Genetic; D056466:Histone Demethylases / Q000378:metabolism; D006657:Histones / Q000378:metabolism; D006801:Humans; D011944:Receptors, Androgen / Q000235:genetics* / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: C410798:AR protein, human; D006657:Histones; D011944:Receptors, Androgen; D056466:Histone Demethylases; C495195:KDM1A protein, human