title: Equine-like G3 rotavirus in Hungary, 2015 - Is it a novel intergenogroup reassortant pandemic strain?
abstract: Novel, intergenogroup reassortant G3 rotavirus strains are spreading in at least three continents: Asia, Australia, and Europe. The present study provides evidence that a closely related G3P[8] strain circulated in Hungary during 2015. Whole genome sequencing and phylogenetic analysis showed that the identified strain continues to evolve by reassortment. This observation demonstrates the genomic plasticity of the novel strain, which is thought to be a prerequisite of the success of emerging rotavirus genotypes.
authors.affiliation: Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences , Budapest, Hungary.
authors.forename: Renáta
authors.initials: R
authors.lastname: Dóró
authors.affiliation: Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences , Budapest, Hungary.
authors.forename: Szilvia
authors.initials: S
authors.lastname: Marton
authors.affiliation: Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences , Budapest, Hungary.
authors.forename: Anett Horváth
authors.initials: AH
authors.lastname: Bartókné
authors.affiliation: Medical Centre of Hungarian Defense Forces, Force Health Laboratory Institute , Budapest, Hungary.
authors.forename: György
authors.initials: G
authors.lastname: Lengyel
authors.affiliation: Combined Szent István and Szent László Hospital , Budapest, Hungary.
authors.forename: Zsófia
authors.initials: Z
authors.lastname: Agócs
authors.affiliation: János Szentágothai Research Centre, University of Pécs , Pécs, Hungary.
authors.forename: Ferenc
authors.initials: F
authors.lastname: Jakab
authors.affiliation: Institute for Veterinary Medical Research, Centre for Agricultural Research, Hungarian Academy of Sciences , Budapest, Hungary.
authors.forename: Krisztián
authors.initials: K
authors.lastname: Bányai
mesh_terms: D000818:Animals; D001208:Asia / Q000453:epidemiology; D001315:Australia / Q000453:epidemiology; D005060:Europe; D005838:Genotype; D006734:Horse Diseases / Q000453:epidemiology / Q000821:virology*; D006736:Horses; D006801:Humans; D006814:Hungary / Q000453:epidemiology; D058873:Pandemics; D010802:Phylogeny; D016865:Reassortant Viruses / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012401:Rotavirus / Q000145:classification / Q000235:genetics / Q000302:isolation & purification*; D012400:Rotavirus Infections / Q000453:epidemiology / Q000662:veterinary* / Q000821:virology*
keywords: next generation sequencing; phylogenetic analysis; surveillance