title: How does epidemiological and clinicopathological features affect survival after gastrectomy for gastric cancer patients-single Egyptian center experience.
abstract: OBJECTIVE
  To investigate the clinicopathological features and the significance of different prognostic factors which predict surgical overall survival in patients with gastric carcinoma.
  
  
  METHODS
  This retrospective study includes 80 patients diagnosed and treated at gastroenterology surgical center, Mansoura University, Egypt between February 2009 to February 2013. Prognostic factors were assessed by cox proportional hazard model.
  
  
  RESULTS
  There were 57 male and 23 female. The median age was 57 years (24-83). One, 3 and 5 years survival rates were 71%, 69% and 46% respectively. The median survival was 69.96 mo. During the follow-up period, 13 patients died (16%). Hospital morbidity was reported in 10 patients (12.5%). The median number of lymph nodes removed was 22 (4-41). Lymph node (LN) involvement was found in 91% of cases. After R0 resection, depth of wall invasion, LN involvement and the number (> 15) of retrieved LN, LN ratio and tumor differentiation predict survival. In multivariable analysis, tumor differentiation, curability of resection and a number of resected LN superior to 15 were found to be independent prognostic factors.
  
  
  CONCLUSIONS
  Surgery remains the cornerstone of treatment. Tumor differentiation, curability of resection and a number of resected LN superior to 15 were found to be independent prognostic factors. Extended LN dissection does not increase the morbidity or mortality rate but markedly improves long term survival.
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Ehab
authors.initials: E
authors.lastname: El Hanafy
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Ayman
authors.initials: A
authors.lastname: El Nakeeb
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Helmy
authors.initials: H
authors.lastname: Ezzat
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Emad
authors.initials: E
authors.lastname: Hamdy
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Ehab
authors.initials: E
authors.lastname: Atif
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Tharwat
authors.initials: T
authors.lastname: Kandil
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Amgad
authors.initials: A
authors.lastname: Fouad
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Mohamed Abdel
authors.initials: MA
authors.lastname: Wahab
authors.affiliation: Ehab El Hanafy, Ayman El Nakeeb, Helmy Ezzat, Emad Hamdy, Ehab Atif, Tharwat Kandil, Amgad Fouad, Mohamed Abdel Wahab, Ahmed Monier, Gastroenterology Surgical Center, Mansoura University, Mansoura 35516, Egypt.
authors.forename: Ahmed
authors.initials: A
authors.lastname: Monier
keywords: Cancer stomach; Lymph node metastasis; Lymph node ratio; Prognostic factors; Recurrence after gastrectomy