title: Circulating Progenitor Cells in Regenerative Technologies: A Realistic Strategy in Bone Regeneration?
abstract: Strategies in skeletal regeneration research have been primarily focused on optimization of three components: cellular progenitors, biomaterials, and growth factors. With the increased understanding that circulating progenitor cells exist in peripheral blood, the question arises whether such cell types would allow for adequate osteogenesis and mineralization. In this review, we discuss the current literature on circulating progenitor cells inin vitroandin vivostudies on bone regeneration.
authors.affiliation: Division of Plastic and Reconstructive Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA.
authors.forename: Jessica B
authors.initials: JB
authors.lastname: Chang
authors.affiliation: Division of Plastic and Reconstructive Surgery, UCLA David Geffen School of Medicine, Los Angeles, CA.
authors.forename: Justine C
authors.initials: JC
authors.lastname: Lee
keywords: Cellular progenitors; Mesenchymal Stem Cells (MSCs); Osteogenesis