title: Application of post-genomic techniques in dog cancer research.
abstract: Omics techniques have been widely applied to veterinary science, although mostly on farm animal productions and infectious diseases. In canine oncology, on the contrary, the use of omics methodologies is still far behind. This review presents the most recent achievement in the application of postgenomic techniques, such as transcriptomics, proteomics, and metabolomics, to canine cancer research. The protocols to recover material suitable for omics analyses from formalin-fixed, paraffin-embedded tissues are presented, and omics applications for biomarker discovery and their potential for cancer diagnostics in veterinary medicine are highlighted.
authors.affiliation: Department of Veterinary Medicine, Università di Milano, Via Celoria 02, 20133 Milano, Italy. fabrizio.ceciliani@unimi.it.
authors.forename: F
authors.initials: F
authors.lastname: Ceciliani
authors.affiliation: Department of Veterinary Medicine, Università di Milano, Via Celoria 02, 20133 Milano, Italy. fabrizio.ceciliani@unimi.it.
authors.forename: P
authors.initials: P
authors.lastname: Roccabianca
authors.affiliation: Department of Veterinary Medicine, Università di Milano, Via Celoria 02, 20133 Milano, Italy. fabrizio.ceciliani@unimi.it.
authors.forename: C
authors.initials: C
authors.lastname: Giudice
authors.affiliation: Department of Veterinary Medicine, Università di Milano, Via Celoria 02, 20133 Milano, Italy. fabrizio.ceciliani@unimi.it.
authors.forename: C
authors.initials: C
authors.lastname: Lecchi
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000379:methods; D030541:Databases, Genetic; D004283:Dog Diseases / Q000175:diagnosis / Q000235:genetics* / Q000378:metabolism; D004285:Dogs; D023281:Genomics / Q000379:methods; D009369:Neoplasms / Q000662:veterinary*