title: The Authors Reply.
authors.affiliation: Statistical Innovation Group, AstraZeneca, Cambridge, United Kingdom.
authors.forename: Jonathan W
authors.initials: JW
authors.lastname: Bartlett
authors.affiliation: Department of Statistics, College of Liberal Arts and Sciences, University of Connecticut, Storrs, CT.
authors.forename: Ofer
authors.initials: O
authors.lastname: Harel
authors.affiliation: Department of Medical Statistics, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology, School of Life and Medical Sciences, University College London, London, United Kingdom.
authors.forename: James R
authors.initials: JR
authors.lastname: Carpenter