title: Microwave heating in peptide side chain modification via cysteine alkylation.
abstract: Microwave irradiation has been successfully applied to a selective synthetic procedure for introducing molecular substituents on peptides, providing a noticeable reduction of the reaction time and also an increased crude peptide purity for some compounds.
authors.affiliation: Institute of Biostructures and Bioimaging, National Research Council, 80134, Naples, Italy.
authors.forename: Enrica
authors.initials: E
authors.lastname: Calce
authors.affiliation: Institute of Biostructures and Bioimaging, National Research Council, 80134, Naples, Italy. stefania.deluca@cnr.it.
authors.forename: Stefania
authors.initials: S
authors.lastname: De Luca
mesh_terms: D000478:Alkylation; D003545:Cysteine / Q000737:chemistry*; D008872:Microwaves; D010455:Peptides / Q000737:chemistry*
chemical_list: D010455:Peptides; D003545:Cysteine
keywords: Cysteine modification; Microwave-assisted protocol; Molecular sieves; Peptide synthesis; Post-synthetic S-alkylation