title: Acute phase proteins disturbances indicate uncompensated obesity declining physical fitness.
abstract: The correlation between physical fitness and health indicators still requires a research aimed at improving the knowledge about physical fitness and the impact of obesity on the health status in children and adolescents. The aim of this study is an analysis of the results of the EUROFIT battery tests in relation to routine laboratory parameters and the inflammation markers.
  
  
  
  In the group of 123 Polish adolescents the routine parameters of lipid metabolism and acute phase proteins were investigated, and compared with EUROFIT motor fitness tests results, expressed as percentiles of the results achieved by healthy Polish population.
  
  
  
  Most of the EUROFIT tests battery were performed by overweight adolescent girls on an insufficient level. Children who were described by parameters indicating more advanced obesity performed the EUROFIT tests worse. There was showed a negative correlation between the concentration of HDL cholesterol and the long jump (rho=-0.304) as well as with the speed of limb movement (rho=-0.277). There was a positive correlation between the speed of limb movement and the concentration of triglycerides (rho=0.335), LDL cholesterol (rho=0.305) and the percentage of the A4 (rho=0.239).
  
  
  
  Disturbed lipid parameters, as well as altered glycosylation profiles of acute phase proteins, were observed in all overweight children, and the intensity of alterations correlated with worse fitness.
authors.affiliation: Chair for Rheumatology and Rehabilitation, Poznań University of Medical Sciences, Poland. idalk@poczta.fm.
authors.forename: M
authors.initials: M
authors.lastname: Sobieska
authors.forename: I
authors.initials: I
authors.lastname: Laudańska-Krzemińska
authors.forename: A
authors.initials: A
authors.lastname: Walczak
authors.forename: N
authors.initials: N
authors.lastname: Klimas
authors.forename: P
authors.initials: P
authors.lastname: Kroll
authors.forename: E
authors.initials: E
authors.lastname: Gajewska
mesh_terms: D000209:Acute-Phase Proteins / Q000378:metabolism*; D000293:Adolescent; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D009765:Obesity / Q000209:etiology / Q000378:metabolism* / Q000628:therapy; D050177:Overweight / Q000378:metabolism; D010809:Physical Fitness; D011044:Poland
chemical_list: D000209:Acute-Phase Proteins