title: Dietary Exposure to Benzyl Butyl Phthalate in China.
abstract: OBJECTIVE
  Benzyl butyl phthalate (BBP) is a plasticizer used in food contact materials. Dietary exposure to BBP might lead to reproduction and developmental damages to human. The present paper was aimed to assess the health risk of BBP dietary exposure in Chinese population.
  
  
  METHODS
  The BBP contents were detected in 7409 food samples from 25 food categories by gas chromatography-mass spectrometry operated in selected ion monitoring (SIM) mode. The dietary exposures of BBP in different age and sex groups were estimated by combining the content data with food consumption data derived from 2002 China National Nutrient and Health Survey, and evaluated according to the tolerable daily intake (TDI) of BBP established by European Food safety Agency.
  
  
  RESULTS
  It was found that BBP was undetectable in most samples and the highest level was 1.69 mg/kg detected in a vegetable oil sample. The average dietary exposure of BBP in people aged ⋝2 years was 1.03 μg/kg bw per day and the highest average exposure was found in 2-6 years old children (1.98 μg/kg bw per day). The BBP exposure in 7-12 months old children excessed 10% of tolerable daily intake (TDI) in worst scenario. .
  
  
  CONCLUSIONS
  The health risk of BBP dietary exposure in Chinese population is low and, considering BBP alone, there is no safety concern.
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Ding Guo
authors.initials: DG
authors.lastname: Jiang
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Hai Xia
authors.initials: HX
authors.lastname: Sui
authors.affiliation: Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, Zhejiang, China.
authors.forename: Ping Gu
authors.initials: PG
authors.lastname: Wu
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Ai Dong
authors.initials: AD
authors.lastname: Liu
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Da Jin
authors.initials: da J
authors.lastname: Yang
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Zhao Ping
authors.initials: ZP
authors.lastname: Liu
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Song
authors.affiliation: Key Laboratory of Food Safety Risk Assessment, National Health and Family Planning Commission of the People's Republic of China (China National Center for Food Safety Risk Assessment), Beijing 100022, China.
authors.forename: Ning
authors.initials: N
authors.lastname: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D002681:China; D004032:Diet; D004781:Environmental Exposure; D004785:Environmental Pollutants / Q000032:analysis*; D005260:Female; D005506:Food Contamination / Q000032:analysis*; D018857:Food Packaging; D008401:Gas Chromatography-Mass Spectrometry; D006801:Humans; D008297:Male; D008875:Middle Aged; D010795:Phthalic Acids / Q000032:analysis*; D010968:Plasticizers / Q000032:analysis*; D055815:Young Adult
chemical_list: D004785:Environmental Pollutants; D010795:Phthalic Acids; D010968:Plasticizers; C027561:butylbenzyl phthalate
keywords: Benzyl butyl phthalate; China; Dietary exposure; Risk assessment