title: Epigenetic Regulation of Myeloid Cells.
abstract: Epigenetic regulation in myeloid cells is crucial for cell differentiation and activation in response to developmental and environmental cues. Epigenetic control involves posttranslational modification of DNA or chromatin, and is also coupled to upstream signaling pathways and transcription factors. In this review, we summarize key epigenetic events and how dynamics in the epigenetic landscape of myeloid cells shape the development, immune activation, and innate immune memory.
authors.affiliation: Arthritis and Tissue Degeneration Program and David Z. Rosensweig Genomics Center, Hospital for Special Surgery, New York, NY 10021.|Department of Medicine and Immunology and Microbial Pathogenesis Program, Weill Cornell Medical College, New York, NY 10021.
authors.forename: Lionel B
authors.initials: LB
authors.lastname: Ivashkiv
authors.affiliation: Arthritis and Tissue Degeneration Program and David Z. Rosensweig Genomics Center, Hospital for Special Surgery, New York, NY 10021.
authors.forename: Sung Ho
authors.initials: SH
authors.lastname: Park
mesh_terms: D000818:Animals; D002454:Cell Differentiation; D049109:Cell Proliferation; D044127:Epigenesis, Genetic; D006801:Humans; D022423:Myeloid Cells / Q000502:physiology*