title: Evaluating the effect of a haemoglobin spray on size reduction in chronic DFUs: clinical outcomes at 12 weeks.
abstract: A recent multi-centre observational evaluation investigated the effect of a topical haemoglobin spray (Granulox, Infirst), used as an adjunct to standard care, on wound size reduction in 17 patients (4 females/13 males) with 20 chronic diabetic foot ulcers (DFUs) over a 4-week period. In 14 of the 18 wounds that completed the evaluation (one patient dropped out due to an infection) there was a mean reduction of 53.8% (range: 11.9-100%). The product was acceptable to both patients and clinicians, who all found it easy to use. This article describes the outcomes for the remaining 13 patients (with 15 wounds) who continued using the spray after the 4-week evaluation ended. (Data are not available for two patients and the one patient who healed during the 4-week evaluation.) By 12 weeks, three wounds (20%) had healed, eight (53%) were progressing towards healing, three (20%) increased in size and one (7%) was slow healing.
authors.affiliation: Advanced Nurse Practitioner, Independent Specialist in Tissue Viability, Wellway Medical Surgeries, Northumberland.
authors.forename: Sharon
authors.initials: S
authors.lastname: Dawn Hunt
authors.affiliation: Advanced Podiatrist, Salford Royal NHS Foundation Trust, Greater Manchester.
authors.forename: Samantha
authors.initials: S
authors.lastname: Haycocks
authors.affiliation: Diabetes Foot Clinical Research Fellow, NHS Lothian, Edinburgh.
authors.forename: Joanne
authors.initials: J
authors.lastname: McCardle
authors.affiliation: Advanced Podiatrist, Pennine Acute Hospitals NHS Trust, Greater Manchester.
authors.forename: Karl
authors.initials: K
authors.lastname: Guttormsen
mesh_terms: D000287:Administration, Topical; D017719:Diabetic Foot / Q000628:therapy*; D005260:Female; D006454:Hemoglobins / Q000627:therapeutic use*; D006801:Humans; D008297:Male; D016896:Treatment Outcome; D014945:Wound Healing
chemical_list: D006454:Hemoglobins
keywords: Diabetic foot ulcer; Patient and clinician satisfaction; Slough reduction; Topical haemoglobin therapy; Wound healing