title: Severe Bronchopulmonary Dysplasia, Growth, Nutrition, and Adipokines at School Age.
abstract: This study evaluated nutrition and growth in relation to plasma adipokine levels in 21 very-low-birth-weight (VLBW) children with radiographic bronchopulmonary dysplasia (BPD), 19 VLBW controls, and 19 term controls with a median age of 11.3 years. We took anthropometric measurements; assessed plasma levels of adipsin, resistin, adiponectin, and leptin; and analyzed the children's 3-day food records. Children with BPD had a smaller age-adjusted head circumference and more microcephaly but no other significant growth differences. Daily recommended nutritional intake levels were poorly met but did not differ between the groups. Leptin levels correlated positively with the body mass index standard deviation score in VLBW children. No other associations between adipokine concentrations and growth were found. There were negative correlations between leptin concentrations and fat intake, resistin levels and carbohydrate intake, and adiponectin, adipsin, and leptin levels and energy intake.
authors.affiliation: Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland.
authors.forename: Piia
authors.initials: P
authors.lastname: Suursalmi
authors.affiliation: Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland.
authors.forename: Päivi
authors.initials: P
authors.lastname: Korhonen
authors.affiliation: Päijät-Häme Central Hospital, Lahti, Finland.
authors.forename: Tarja
authors.initials: T
authors.lastname: Kopeli
authors.affiliation: Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland.
authors.forename: Riina
authors.initials: R
authors.lastname: Nieminen
authors.affiliation: University of Tampere, Tampere, Finland.
authors.forename: Tiina
authors.initials: T
authors.lastname: Luukkaala
authors.affiliation: Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland.
authors.forename: Eeva
authors.initials: E
authors.lastname: Moilanen
authors.affiliation: Tampere University Hospital, Tampere, Finland; University of Tampere, Tampere, Finland.
authors.forename: Outi
authors.initials: O
authors.lastname: Tammela
keywords: adipokines; bronchopulmonary dysplasia; growth; microcephaly; nutrition