title: Synthetic Fillers for Facial Rejuvenation.
abstract: Soft tissue filler procedures have increased dramatically in popularity in the United States. Synthetic fillers such as calcium hydroxyapatite (CaHA), polymethyl methacrylate (PMMA), and poly-l-lactic acid (PLLA), and silicone provide initial volume replacement but have an additional biostimulatory effect to supplement facial volumization. Indications include human immunodeficiency virus lipoatrophy and nasolabial folds for CaHA and PLLA and atrophic acne scars for PMMA. Most clinical use of these synthetic fillers is in an off-label fashion. Beyond the proper choice of a synthetic filler, careful consideration of dilution, injection method, and postprocedural care allows for successful and consistent results.
authors.affiliation: Private Practice, Enhance Medical Center, 462 North Linden Drive, Suite 333, Beverly Hills, CA 90212, USA. Electronic address: JCLMD@enhancemedicalcenter.com.
authors.forename: Johnson C
authors.initials: JC
authors.lastname: Lee
authors.affiliation: Lorenc Aesthetic Plastic Surgery Center, 983 Park Avenue, New York, NY 10028, USA.
authors.forename: Z Paul
authors.initials: ZP
authors.lastname: Lorenc
mesh_terms: D003357:Cosmetic Techniques; D000067548:Dermal Fillers / Q000627:therapeutic use*; D017886:Durapatite / Q000627:therapeutic use; D005145:Face; D006801:Humans; D007279:Injections, Subcutaneous; D011091:Polyesters / Q000627:therapeutic use; D019904:Polymethyl Methacrylate / Q000627:therapeutic use; D012060:Rejuvenation; D012827:Silicone Oils / Q000627:therapeutic use; D015595:Skin Aging
chemical_list: D000067548:Dermal Fillers; D011091:Polyesters; D012827:Silicone Oils; C033616:poly(lactide); D019904:Polymethyl Methacrylate; D017886:Durapatite
keywords: CaHA; Fillers; Injectables; PLLA; PMMA; Silicone; Synthetic