title: The Prevalence of High Antiretroviral Coverage and Viral Suppression in Japan: an Excellent Profile for a Downstream Human Immunodeficiency Virus Care Spectrum.
abstract: We investigated the effectiveness of the Japanese health care system for human immunodeficiency virus/acquired immunodeficiency virus (HIV/AIDS), in terms of prevention, diagnosis, access to antiretroviral treatment, and treatment outcomes. Clinical information on HIV/AIDS cases was collected via questionnaires sent to 377 registered HIV/AIDS clinics in Japan. Data on 9,040 and 14,569 cases were collected in 2009 and 2014, respectively. The percentages of cases undergoing treatment were 69.6% and 87.8% in 2009 and 2014, respectively, demonstrating an improvement in treatment coverage over the 5 years between the 2 surveys. The proportion of cases with undetectable HIV RNA in the 2014 survey was 87.7%. Thus, our survey revealed that the 2 of the United Nations AIDS Fast-Track targets, 90% treated and 90% virally suppressed, are close to being achieved. However, Japan appears to have fallen short of the upstream target of 90% diagnosed. Japan needs to radically reform its strategies for encouraging people to undergo HIV testing and to develop a system for estimating the number of people living with HIV.
authors.affiliation: The Institute of Medical Science, The University of Tokyo.
authors.forename: Naoko
authors.initials: N
authors.lastname: Miyazaki
authors.forename: Wataru
authors.initials: W
authors.lastname: Sugiura
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Gatanaga
authors.forename: Dai
authors.initials: D
authors.lastname: Watanabe
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Yokomaku
authors.forename: Kazuhisa
authors.initials: K
authors.lastname: Yoshimura
authors.forename: Shuzo
authors.initials: S
authors.lastname: Matsushita
mesh_terms: D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D004363:Drug Utilization; D006678:HIV / Q000302:isolation & purification*; D015658:HIV Infections / Q000175:diagnosis / Q000188:drug therapy* / Q000517:prevention & control / Q000821:virology*; D006297:Health Services Accessibility; D006302:Health Services Research; D006801:Humans; D007564:Japan; D011795:Surveys and Questionnaires; D000072230:Sustained Virologic Response; D019562:Viral Load
chemical_list: D044966:Anti-Retroviral Agents