title: Pathologic aspects of skull base tumors.
abstract: Skull base tumors form a highly heterogeneous group. As there are several structures in this anatomical site, a large number of different primary malignancies might develop, as well as a variety of secondary (metastatic) tumors. In this article, the most common malignancies are presented, along with a short histopathologic description. For some entities, an immunohistochemical profile is also given that should be helpful in proper diagnosis. As many pathologic diagnoses nowadays also include genetic studies, the most common genetic abnormalities in skull base tumors are presented.
authors.affiliation: Department of Cancer Pathology, Greater Poland Center of Oncology, Poznan, Poland; Department of Cancer Pathology and Prophylactics, Poznan University of Medical Sciences, Poznan, Poland; Department of Clinical Pathomorphology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
authors.forename: Andrzej
authors.initials: A
authors.lastname: Marszałek
authors.affiliation: Department of Clinical Pathomorphology, Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Torun, Poland.
authors.forename: Łukasz
authors.initials: Ł
authors.lastname: Szylberg
authors.affiliation: Department of Cancer Pathology, Greater Poland Center of Oncology, Poznan, Poland.
authors.forename: Sławomir
authors.initials: S
authors.lastname: Wiśniewski
keywords: Benign; Histopathology; Malignant; Skull base tumors