title: [Comparative Study on Effects of Anti-contusion Injury, Analgesia and Anti-inflammation of Root and Stem of Zanthoxylum nitidum].
abstract: OBJECTIVE
  To provide the scientific evidence for expansion of medicinal parts of Zanthoxylum nitidum by comparing the effects of anti-contusion injury, analgesia and anti-inflammation of its root and stem.
  
  
  METHODS
  The pharmacological effects between root and stem of Zanthoxylum nitidum were compared by observing the anti-injury effect in rats with injury struck by hammer. The analgesic effect in mice was evaluated by writhing test and hot plate test, and the anti-inflammatory effect on paw edema induced by carrageenan and granuloma induced by cotton pellet were investigated in rats.
  
  
  RESULTS
  Both root and stem of Zanthoxylum nitidum relieved the exterior and histological symptoms of rats' injury legs struck by hammer, decreased the numbers of mice's writhing, enhanced pain threshold of mice on heat plate, inhibited the edema of rats induced by carrageenan, and suppressed the granuloma of rats induced by cotton pellet.
  
  
  CONCLUSIONS
  Stem of Zanthoxylum nitidum has similar effects of anti-contusion injury, analgesia and anti-inflammation with root of Zanthoxylum nitidum.
authors.forename: Wei-xuan
authors.initials: WX
authors.lastname: Chen
authors.forename: Ze-hui
authors.initials: ZH
authors.lastname: Qin
authors.forename: Dan
authors.initials: D
authors.lastname: Zeng
authors.forename: Zheng-zhou
authors.initials: ZZ
authors.lastname: Han
authors.forename: Ruo-ting
authors.initials: RT
authors.lastname: Zhan
authors.forename: Ying
authors.initials: Y
authors.lastname: Tan
authors.forename: Wei-wen
authors.initials: WW
authors.lastname: Chen
mesh_terms: D000700:Analgesics / Q000494:pharmacology*; D000818:Animals; D000893:Anti-Inflammatory Agents / Q000494:pharmacology*; D002351:Carrageenan; D003288:Contusions / Q000188:drug therapy*; D004487:Edema / Q000139:chemically induced / Q000188:drug therapy; D007249:Inflammation / Q000188:drug therapy; D051379:Mice; D010146:Pain / Q000188:drug therapy; D017288:Pain Threshold; D010936:Plant Extracts / Q000494:pharmacology*; D018517:Plant Roots / Q000737:chemistry; D018547:Plant Stems / Q000737:chemistry; D051381:Rats; D032106:Zanthoxylum / Q000737:chemistry*
chemical_list: D000700:Analgesics; D000893:Anti-Inflammatory Agents; D010936:Plant Extracts; D002351:Carrageenan