title: [CD36 Antigen Deficiency and Platelet Transfusion].
abstract: CD36 is a transmembrane glycoprotein, a multi-ligand receptor, possesses various biological functions. CD36 deficiency may stimulate the body to produce anti-CD36 alloimmune antibodies through the several pathways, such as blood transfusion, pregnancy or organ transplantation and so on, leading to the refractoriness of immune platelet transfusion and other diseases. The recent research advances of CD36 deficiency and its molecular biological basis, platelet transfusion and CD36 antibody detection are summarized briefey in this review.
authors.affiliation: Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning 530007, Guangxi Province, China.
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Li
authors.affiliation: Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning 530007, Guangxi Province, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Nanning Institute of Transfusion Medicine, Nanning Blood Center, Nanning 530007, Guangxi Province, China. E-mail: nanningshenweidong@163.com.
authors.forename: Wei-Dong
authors.initials: WD
authors.lastname: Shen
mesh_terms: D001323:Autoantibodies / Q000097:blood; D001791:Blood Platelet Disorders; D001792:Blood Platelets; D001803:Blood Transfusion; D018955:CD36 Antigens / Q000172:deficiency*; D005260:Female; D030342:Genetic Diseases, Inborn; D006648:Histocompatibility; D006801:Humans; D017713:Platelet Transfusion; D011247:Pregnancy
chemical_list: D001323:Autoantibodies; D018955:CD36 Antigens