title: Clinical relevance of infections with zoonotic and human oral species of Campylobacter.
abstract: Genus Campylobacter has been recognized as a causative bacterial agent of animal and human diseases. Human Campylobacter infections have caused more concern. Campylobacters can be classified into two groups in terms of their original host: zoonotic and human oral species. The major zoonotic species are Campylobacter jejuni and Campylobacter coli, which mostly reside in the intestines of avian species and are transmitted to humans via consumption of contaminated poultry products, thus causing human gastroenteritis and other diseases as sequelae. The other campylobacters, human oral species, include C. concisus, C. showae, C. gracilis, C. ureolyticus, C. curvus, and C. rectus. These species are isolated from the oral cavity, natural colonization site, but have potential clinical relevance in the periodontal region to varying extent. Two species, C. jejuni and C. coli, are believed to be mainly associated with intestinal diseases, but recent studies suggested that oral Campylobacter species also play a significant role in intestinal diseases. This review offers an outline of the two Campylobacter groups (zoonotic and human oral), their virulence traits, and the associated illnesses including gastroenteritis.
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea.
authors.forename: Soomin
authors.initials: S
authors.lastname: Lee
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea.
authors.forename: Jeeyeon
authors.initials: J
authors.lastname: Lee
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea.
authors.forename: Jimyeong
authors.initials: J
authors.lastname: Ha
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea.
authors.forename: Yukyung
authors.initials: Y
authors.lastname: Choi
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea.
authors.forename: Sejeong
authors.initials: S
authors.lastname: Kim
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea.
authors.forename: Heeyoung
authors.initials: H
authors.lastname: Lee
authors.affiliation: Department of Food and Nutrition, Sookmyung Women's University, Seoul, 04310, Republic of Korea. yyoon@sookmyung.ac.kr.
authors.forename: Yohan
authors.initials: Y
authors.lastname: Yoon
authors.affiliation: Department of Oral Microbiology, College of Dentistry, Wonkwang University, Iksan, Chonbuk, 54538, Republic of Korea. kheechoi@wonkwang.ac.kr.
authors.forename: Kyoung-Hee
authors.initials: KH
authors.lastname: Choi
mesh_terms: D000818:Animals; D001717:Birds / Q000382:microbiology; D002167:Campylobacter / Q000145:classification / Q000235:genetics / Q000254:growth & development / Q000302:isolation & purification*; D002169:Campylobacter Infections / Q000382:microbiology* / Q000635:transmission; D006801:Humans; D007422:Intestines / Q000382:microbiology; D009055:Mouth / Q000382:microbiology*; D015047:Zoonoses / Q000382:microbiology* / Q000635:transmission
keywords: Campylobacter; gastroenteritis; inflammatory bowel disease; periodontitis