title: Insights into the epidemiology and management of lupus nephritis from the US rheumatologist's perspective.
abstract: Lupus nephritis is a common and severe manifestation of systemic lupus erythematosus that disproportionately affects nonwhites and those in lower socioeconomic groups. This review discusses recent data on the incidence, prevalence, and outcomes of patients with lupus nephritis with a focus on low-income US Medicaid patients. We also review recent guidelines on diagnosis, treatment, and screening for new onset and relapses of lupus nephritis. Finally, we discuss the management of lupus nephritis from a rheumatologist's perspective, including vigilance for the common adverse events related to disease and treatment, and we review prevention and new treatment strategies.
authors.affiliation: Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA. Electronic address: phoover@partners.org.
authors.forename: Paul J
authors.initials: PJ
authors.lastname: Hoover
authors.affiliation: Lupus Center, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
authors.forename: Karen H
authors.initials: KH
authors.lastname: Costenbader
mesh_terms: D000284:Administration, Oral; D017024:Chemotherapy, Adjuvant; D005938:Glucocorticoids / Q000008:administration & dosage / Q000009:adverse effects* / Q000627:therapeutic use; D006297:Health Services Accessibility; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage / Q000009:adverse effects / Q000627:therapeutic use*; D015994:Incidence; D008181:Lupus Nephritis / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology*; D008484:Medicaid; D055118:Medication Adherence; D017410:Practice Guidelines as Topic; D015995:Prevalence; D000072140:Rheumatologists; D012307:Risk Factors; D012959:Socioeconomic Factors; D016896:Treatment Outcome; D014481:United States
chemical_list: D005938:Glucocorticoids; D007166:Immunosuppressive Agents
keywords: epidemiology; glomerulonephritis; lupus