title: Primary cardiac angiosarcoma: a prolonged response to surgical resection followed by concurrent chemoradiotherapy with docetaxel.
abstract: BACKGROUND
  Primary cardiac cancer is a very rare disease, among which primary cardiac angiosarcoma is one of the most frequent type and is characterized by extremely poor prognosis without established optimal treatment.
  
  
  METHODS
  Here we report a case of primary cardiac angiosarcoma with hemorrhagic pericardial effusion who achieved a durable response with tumor excision followed by concurrent chemoradiotherapy with docetaxel. A sixty year old man was presented with dyspnea and was diagnosed with primary cardiac angiosarcoma with hemorrhagic pericardial effusion. After surgical excision of primary tumor with microscopic residual disease followed by concurrent chemoradiotherapy with docetaxel, the patient showed durable response of progression free survival of 12 months.
  
  
  RESULTS
  This case shows benefit of concurrent chemoradiotherapy with taxane. Further investigation of aggressive multimodal treatment strategy is warranted for primary cardiac angiosarcoma with pauci-metastasis even when achievement of complete resection seems unlikely.
authors.affiliation: Department of Internal Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760 Republic of Korea.
authors.forename: Youngwoo
authors.initials: Y
authors.lastname: Jang
authors.affiliation: Department of Internal Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760 Republic of Korea.
authors.forename: Joonhwan
authors.initials: J
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760 Republic of Korea.
authors.forename: Jung Woo
authors.initials: JW
authors.lastname: Shim
authors.affiliation: Department of Radiology, Gachon University Gil Medical Center, Incheon, Republic of Korea.
authors.forename: Eun Young
authors.initials: EY
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760 Republic of Korea.
authors.forename: Jungkeun
authors.initials: J
authors.lastname: Moon
authors.affiliation: Department of Pathology, Gachon University Gil Medical Center, Incheon, Republic of Korea.
authors.forename: Jungsuk
authors.initials: J
authors.lastname: An
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, Gachon University Gil Medical Center, Incheon, Republic of Korea.
authors.forename: Yang Bin
authors.initials: YB
authors.lastname: Jeon
authors.affiliation: Department of Radiation Oncology, Gachon University Gil Medical Center, Incheon, Republic of Korea.
authors.forename: Kyu Chan
authors.initials: KC
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Gachon University Gil Medical Center, 1198 Guwol-dong, Namdong-gu, Incheon, 405-760 Republic of Korea.
authors.forename: Hee Kyung
authors.initials: HK
authors.lastname: Ahn
keywords: Chemotherapy; Docetaxel; Primary cardiac angiosarcoma; Radiotherapy; Surgery