title: The study of sleep disorder factors in patients with Guillain-Barré syndrome.
abstract: In this study, we explore the sleep disorders and its associated factors in patients with Guillain-Barré syndrome (GBS), so as to work out appropriate interventions to promote early recovery of the patients. This study subjects included 49 patients with GBS who had been admitted to the Department of Neurology at The Affiliated Hospital of Hebei University, fulfilling National Institute of Neurological and Communicative Diseases and Stroke (NINCDS) criteria for GBS; 37 cases were male and 12 female (age: 27-68 years). Patients were evaluated once daily for two consecutive weeks. By using Wong and Baker Face Scale (WBFS) to evaluate the numbness and pain in patients, 0 points representing completely no pain and 10 points represents the most severity of the pain reactions; the same applies for numbness. The GBS Disability Scale (GBS DS) is used to evaluate the severity of GBS. The Hospital Anxiety and Depression Scale (HADS) is used to evaluate the anxiety and depression the patient is experiencing. All patients take routine EMG and sleep EEG. The sleep quality of the subjects was evaluated by the Pittsburgh Sleep Quality Index Scale (PSQI) and Richard Campbell Sleep Rating Scale. This study found that the application of ventilators, numbness, anxiety and severe limb movement disorders are the main factors causing sleep disorders. Cerebrospinal fluid (CSF) protein concentration is also associated with sleep disorders. But, no obvious abnormalities were found in sleep EEG. The application of the ventilator, numbness, anxiety and severe limb movement disorder are main factors causing sleep disorders. CSF protein concentration is also associated with sleep disorders.
authors.affiliation: a Department of Neurology , The Affiliated Hospital of Hebei University , Baoding , Hebei , PR China.
authors.forename: Juan
authors.initials: J
authors.lastname: Gao
authors.affiliation: b Department of Medicine , Hebei University , Baoding , Hebei , PR China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Li
authors.affiliation: c Department of Neurology , Second Hospital of Hebei Medical University , Shijiazhuang , Hebei , PR China.
authors.forename: Yafei
authors.initials: Y
authors.lastname: Sun
authors.affiliation: d Department of Rehabilitation , The Affiliated Hospital of Hebei University , Baoding , Hebei , PR China.
authors.forename: Weihua
authors.initials: W
authors.lastname: Hu
authors.affiliation: b Department of Medicine , Hebei University , Baoding , Hebei , PR China.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: b Department of Medicine , Hebei University , Baoding , Hebei , PR China.
authors.forename: Di
authors.initials: D
authors.lastname: An
authors.affiliation: e Department of General Medicine , The First Central Hospital of Baoding City , Baoding , Hebei , PR China.
authors.forename: Yuhong
authors.initials: Y
authors.lastname: Yin
mesh_terms: D000328:Adult; D000368:Aged; D004569:Electroencephalography; D004576:Electromyography; D005260:Female; D020275:Guillain-Barre Syndrome / Q000134:cerebrospinal fluid / Q000150:complications* / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010147:Pain Measurement; D012720:Severity of Illness Index; D012893:Sleep Wake Disorders / Q000134:cerebrospinal fluid / Q000209:etiology* / Q000503:physiopathology*
keywords: CSF protein; GBS; mechanical ventilation; sleep EEG; sleep disorder; sleep rating scale