title: Cardioprotection by Phytochemicals via Antiplatelet Effects and Metabolism Modulations.
abstract: The multi-factorial aetiology is the characteristic element of cardiac disorders. Further scientific research had recognized for a long time that platelet function is related to the risk of developing atherosclerosis. Activated blood platelets play a central role in this chronic inflammatory condition as they contribute to plaque formation within blood vessels in the early stages of atherogenesis. The present review article summarizes the cardioprotective role played by Phytochemicals via antiplatelet effects. Also, various metabolic modifications have been included that have protective effect during cardiac pathology.
authors.affiliation: Department of Cardiology, Xuzhou Central Hospital, No. 199 South Jiefang Road, Xuzhou, 221009, Jiangsu, China. contribution026@163.com.
authors.forename: Pei-Ying
authors.initials: PY
authors.lastname: Zhang
mesh_terms: D000818:Animals; D001792:Blood Platelets / Q000187:drug effects*; D002316:Cardiotonic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000517:prevention & control; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D006801:Humans; D017705:Lignans / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D064209:Phytochemicals / Q000494:pharmacology* / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000494:pharmacology* / Q000627:therapeutic use; D059808:Polyphenols / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D013267:Stilbenes / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D013634:Tannins / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D002316:Cardiotonic Agents; D005419:Flavonoids; D017705:Lignans; D064209:Phytochemicals; D010975:Platelet Aggregation Inhibitors; D059808:Polyphenols; D013267:Stilbenes; D013634:Tannins
keywords: Antiplatelet effects; Cardioprotection; Curcumin; Metabolism modulation; Phenolics; Phytochemical; Polyphenols; Resveratrol