title: Hashimoto's thyroiditis and papillary carcinoma in an adolescent girl: A case report.
abstract: Hashimoto's thyroiditis with thyroid cancer in childhood is not as common in the adult population. Hashimoto's thyroiditis is an autoimmune disease associated with autoantibodies, and the association between Hashimoto's thyroiditis and papillary carcinoma of the thyroid remains controversial. The present study reported a 15-year-old adolescent girl with the diagnosis of Hashimoto's thyroiditis with thyroid cancer. With the complexity of the clinical manifestations of Hashimoto's thyroiditis, it can be expressed as not only hyperthyroidism or hypothyroidism, but also normal thyroid function. The long-term treatment, and for children with thyroid cancer, early diagnosis is particularly difficult. In the present case, the diagnosis of Hashimoto's thyroiditis is primarily based on clinical manifestations, anti-thyroglobulin antibody and anti-thyroid microsomal antibody. The only diagnostic imaging ultrasound was negative. The present study discussed the possible reason and the identification of this unique case of Hashimoto's thyroiditis with thyroid cancer.
authors.affiliation: Department of Pediatrics, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Li-Qun
authors.initials: LQ
authors.lastname: Dong
authors.affiliation: Department of Pediatrics, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Xiao-Mei
authors.initials: XM
authors.lastname: Sun
authors.affiliation: Department of Pediatrics, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Cheng-Fa
authors.initials: CF
authors.lastname: Xiang
authors.affiliation: Department of Pediatrics, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Jin
authors.initials: J
authors.lastname: Wu
authors.affiliation: National Center for Birth Defect Monitoring, West China Second University Hospital, Sichuan University, Chengdu, Sichuan 610041, P.R. China.
authors.forename: Ping
authors.initials: P
authors.lastname: Yu
keywords: Hashimoto's thyroiditis; adolescent; papillary carcinoma of the thyroid