title: Incidence of allergic rhinitis and meteorological variables: Non-linear correlation and non-linear regression analysis based on Yunqi theory of chinese medicine.
abstract: OBJECTIVE
  To analyze the correlations between the incidence of allergic rhinitis (AR) and meteorological variables of previous periods, so as to establish non-linear prediction equations of AR in Beijing area.
  
  
  METHODS
  AR patients (10,478 cases) collected from Beijing Tongren Hospital during 2007-2010 and meteorological data (including daily average temperature, daily maximum temperature, daily minimum temperature, daily relative humidity, daily average vapor pressure, daily dew point temperature, daily precipitation, daily average wind speed, sea level pressure, and degree of comfort) collected from Beijing Municipal Meteorological Observatory in the same periods were used for the analysis. Non-linear correlation and regression were adopted to analyze the relationship between AR incidence and meteorological variables of former six-qi stage which was defined according to Yunqi theory of Chinese medicine. Comprehensive meteorological parameter was introduced to establish the predictive model.
  
  
  RESULTS
  The high incidence of AR appeared in the 4th qi stage (from the Beginning of Autumn to Autumn Equinox), while the changes of meteorological variables appeared in the 3rd qi stage (from Grain in Beard to Greater Heat), which advanced one phase. The incidence of AR was closely associated with vapor pressure. The correlation coeffifi cients of two predictive models were between 0.8931-0.9176 and all of them have passed signififi cant statistical tests, which showed a satisfactory fifi tting effect.
  
  
  CONCLUSIONS
  Comprehensive meteorological parameters can be used to forecast AR incidence, which is benefifi cial to AR prevention.
authors.affiliation: Beijing Municipal Meteorological Observatory, Beijing, 100089, China.
authors.forename: De-Shan
authors.initials: DS
authors.lastname: Zhang
authors.affiliation: School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
authors.forename: Xuan
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Beijing Otolaryngology Institute, Beijing, 100005, China.
authors.forename: Yu-Hui
authors.initials: YH
authors.lastname: Ouyang
authors.affiliation: Beijing Otolaryngology Institute, Beijing, 100005, China.
authors.forename: Luo
authors.initials: L
authors.lastname: Zhang
authors.affiliation: School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing, 100029, China.
authors.forename: Shi-Lei
authors.initials: SL
authors.lastname: Ma
authors.affiliation: School of Basic Medical Science, Beijing University of Chinese Medicine, Beijing, 100029, China. hejuan6428@sina.com.
authors.forename: Juan
authors.initials: J
authors.lastname: He
keywords: Chinese medicine; Yunqi; allergic rhinitis; comprehensive meteorological parameter; five circuits and six qi; forecast; non-linear correlation