title: Synthesis of β-arylated alkylamides via Pd-catalyzed one-pot installation of a directing group and C(sp(3))-H arylation.
abstract: The synthesis of β-arylated alkylamides via alkyl C-H bond arylation has been realized by means of direct one-pot reactions of acyl chlorides, aryl iodides and 8-aminoquinoline. Depending on the structure of the starting materials, both single and double β-arylated alkylamides could be accessed.
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022 P. R. China.
authors.forename: Yunyun
authors.initials: Y
authors.lastname: Liu
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022 P. R. China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Research Center of Analysis and Measurement, Zhejiang University of Technology, 18 Chaowang Road, Hangzhou, Zhejiang 310014, P.R. China.
authors.forename: Xiaoji
authors.initials: X
authors.lastname: Cao
authors.affiliation: College of Chemistry and Chemical Engineering, Jiangxi Normal University, Nanchang 330022 P. R. China.
authors.forename: Jie-Ping
authors.initials: JP
authors.lastname: Wan
keywords: C–H arylation; alkylamides; directing group; in situ installation; one-pot