title: Comparison of the extent to which total hip and total knee arthroplasty restore patient-reported physical function.
abstract: To evaluate the extent to which elective total hip arthroplasty (THA) and total knee arthroplasty (TKA) for osteoarthritis (OA) restore normal patient-reported physical function in men and women.
  
  
  
  Pain and physical function (WOMAC-PF) were prospectively measured pre- and post-operatively. The relationship between surgical procedure and achieving physical function equivalent to age and sex-matched adults with no hip or knee joint problems was modeled using sex-specific logistic regression. Percent change in function was also compared between groups using sex-specific generalized linear models adjusted for age, BMI, pain, comorbid conditions, time from surgery, and subsequent surgery.
  
  
  
  Individuals with pre- and post-operative WOMAC data were classified exclusively into either THA (287M:306F) or TKA (239M:424F) groups. The median follow-up was 476 (THA) and 474 (TKA) days for men, and 495 (THA) and 526 (TKA) days for women.
  
  
  
  women with THA compared with TKA were more likely to achieve a normal level of postoperative PF while there were no significant differences between procedures in men. Additional analyses: we found slightly lower preoperative PF in THA compared with TKA. This difference resolved postoperatively in men, but women who underwent THA reported greater improvement and better PF than those who had TKA.
  
  
  
  In women, THA results in greater improvement in WOMAC-PF at approximately 1-year follow-up and better approximates physical function of community-dwelling older adults without OA than TKA does. In contrast, in men, a lack of between-group post-operative WOMAC-PF differences suggests that procedures result in a similar degree of improvement.
authors.affiliation: Department of Orthopedics & Rehabilitation, The University of Iowa Hospitals & Clinics, USA.
authors.forename: N A
authors.initials: NA
authors.lastname: Glass
authors.affiliation: Department of Rehabilitation Medicine, The University of Kansas, Kansas City, KS, USA; Department of Epidemiology, College of Public Health, The University of Iowa, USA. Electronic address: segal-research@uiowa.edu.
authors.forename: N A
authors.initials: NA
authors.lastname: Segal
authors.affiliation: Department of Orthopedics & Rehabilitation, The University of Iowa Hospitals & Clinics, USA.
authors.forename: J J
authors.initials: JJ
authors.lastname: Callaghan
authors.affiliation: Department of Orthopedics & Rehabilitation, The University of Iowa Hospitals & Clinics, USA.
authors.forename: C R
authors.initials: CR
authors.lastname: Clark
authors.affiliation: Department of Orthopedics & Rehabilitation, The University of Iowa Hospitals & Clinics, USA.
authors.forename: N O
authors.initials: NO
authors.lastname: Noiseux
authors.affiliation: Department of Orthopedics & Rehabilitation, The University of Iowa Hospitals & Clinics, USA.
authors.forename: Y
authors.initials: Y
authors.lastname: Gao
authors.affiliation: Department of Orthopedics & Rehabilitation, The University of Iowa Hospitals & Clinics, USA.
authors.forename: R
authors.initials: R
authors.lastname: Johnston
mesh_terms: D019644:Arthroplasty, Replacement, Hip; D019645:Arthroplasty, Replacement, Knee; D005260:Female; D006801:Humans; D007719:Knee Joint; D008297:Male; D010003:Osteoarthritis; D010146:Pain
keywords: Osteoarthritis; Physical function; Total hip arthroplasty; Total knee arthroplasty