title: Efficient Ni(II)2Ln(III)2 Electrocyclization Catalysts for the Synthesis of trans-4,5-Diaminocyclopent-2-enones from 2-Furaldehyde and Primary or Secondary Amines.
abstract: A series of heterometallic coordination clusters (CCs) [Ni(II)2Ln(III)2(L1)4Cl2(CH3CN)2] 2CH3CN [Ln = Y (1Y), Sm (1Sm), Eu (1Eu), Gd (1Gd), or Tb (1Tb)] were synthesized by the reaction of (E)-2-(2-hydroxy-3-methoxybenzylidene-amino)phenol) (H2L1) with NiCl2·6(H2O) and LnCl3·x(H2O) in the presence of Et3N at room temperature. These air-stable CCs can be obtained in very high yields from commercially available materials and are efficient catalysts for the room-temperature domino ring-opening electrocyclization synthesis of trans-4,5-diaminocyclopent-2-enones from 2-furaldehyde and primary or secondary amines under a non-inert atmosphere. Structural modification of the catalyst to achieve immobilization or photosensitivity is possible without deterioration in catalytic activity.
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: Kieran
authors.initials: K
authors.lastname: Griffiths
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: Prashant
authors.initials: P
authors.lastname: Kumar
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: James D
authors.initials: JD
authors.lastname: Mattock
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: Alaa
authors.initials: A
authors.lastname: Abdul-Sada
authors.affiliation: UK National Crystallography Service, Chemistry, University of Southampton , Highfield Campus, Southampton, SO17 1BJ, United Kingdom.
authors.forename: Mateusz B
authors.initials: MB
authors.lastname: Pitak
authors.affiliation: UK National Crystallography Service, Chemistry, University of Southampton , Highfield Campus, Southampton, SO17 1BJ, United Kingdom.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Coles
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: Oscar
authors.initials: O
authors.lastname: Navarro
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Vargas
authors.affiliation: Department of Chemistry, School of Life Sciences, University of Sussex , Brighton BN1 9QJ, United Kingdom.
authors.forename: George E
authors.initials: GE
authors.lastname: Kostakis