title: Kazakh Ziziphora Species as Sources of Bioactive Substances.
abstract: Ziziphora species represent the prototypical example of the Lamiaceae family. The phytochemicals present in Ziziphora include monoterpenic essential oils, triterpenes and phenolic substances belonging to the flavonoids. In Kazakh traditional medicine, Ziziphora species possess several medicinal uses. In particular, Z. bungeana Lam. and Z. clinopodioides Lam. are used for the treatment of illnesses related to the cardiovascular system or to combat different infections. Unfortunately, the majority of the information about the complex Ziziphora species is only available in Russian and Chinese language, therefore, we decided gather all available information on Kazakhstan Ziziphora, namely its content compounds, medicinal uses and published patents, to draw the attention of scientists to this very interesting plant with high medicinal potential.
authors.affiliation: Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Brno 61242, Czech Republic. karel.mejkal@post.cz.
authors.forename: Karel
authors.initials: K
authors.lastname: Šmejkal
authors.affiliation: Department of Natural Drugs, Faculty of Pharmacy, University of Veterinary and Pharmaceutical Sciences Brno, Brno 61242, Czech Republic. milan.malanik@seznam.cz.
authors.forename: Milan
authors.initials: M
authors.lastname: Malaník
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, Kazakh National Medical University, Almaty 050000, Kazakhstan. zhaparkulovakarlygash@mail.ru.
authors.forename: Karlygash
authors.initials: K
authors.lastname: Zhaparkulova
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, Kazakh National Medical University, Almaty 050000, Kazakhstan. sakipova.zb@gmail.com.
authors.forename: Zuriyadda
authors.initials: Z
authors.lastname: Sakipova
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, Kazakh National Medical University, Almaty 050000, Kazakhstan. ibadullaeva.g@kaznmu.kz.
authors.forename: Liliya
authors.initials: L
authors.lastname: Ibragimova
authors.affiliation: Department of Pharmaceutical Technology, Faculty of Pharmacy, Kazakh National Medical University, Almaty 050000, Kazakhstan. ibragimova.l@kaznmu.kz.
authors.forename: Galya
authors.initials: G
authors.lastname: Ibadullaeva
authors.affiliation: Department of Pharmacognosy and Botany, The University of Veterinary Medicine and Pharmacy in Košice, Košice 04181, Slovakia. zemlickam1@gmail.com.
authors.forename: Milan
authors.initials: M
authors.lastname: Žemlička
mesh_terms: D000818:Animals; D001688:Biological Products / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology*; D005419:Flavonoids / Q000737:chemistry / Q000494:pharmacology; D006801:Humans; D009822:Oils, Volatile / Q000737:chemistry / Q000494:pharmacology; D064209:Phytochemicals / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D043982:Rhizophoraceae / Q000737:chemistry*
chemical_list: D001688:Biological Products; D005419:Flavonoids; D009822:Oils, Volatile; D064209:Phytochemicals
keywords: Ziziphora; antibacterial; cardiovascular; essential oil; flavonoid; triterpene