title: Invasive aspergillosis in the aortic arch with infectious Aspergillus lesions in pulmonary bullae.
abstract: A patient with pulmonary bullae died of massive hemoptysis. At autopsy a hole was observed in the aortic wall. A microscopic examination indicated small Aspergillus lesions in pulmonary bullae and extensive necrotic lesions with Aspergillus hyphae in the media of the thoracic aorta. These findings led to a diagnosis of invasive aspergillosis in the aortic arch. This is a rare case in which Aspergillus invaded the aorta in a patient without hematologic neoplasms or neutropenia.
authors.affiliation: Department of Respiratory Diseases, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
authors.forename: Isao
authors.initials: I
authors.lastname: Watanabe
authors.affiliation: Laboratory of Diagnostic Pathology, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
authors.forename: Takahisa
authors.initials: T
authors.lastname: Nakayama
authors.affiliation: Laboratory of Diagnostic Pathology, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
authors.forename: Eiji
authors.initials: E
authors.lastname: Yamada
authors.affiliation: Department of Respiratory Diseases, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
authors.forename: Mitsuhiro
authors.initials: M
authors.lastname: Tsukino
authors.affiliation: Department of Respiratory Diseases, Hikone Municipal Hospital, 1882 Hassaka-cho, Hikone, Shiga, Hikone 522-8539, Japan.
authors.forename: Eiichi
authors.initials: E
authors.lastname: Hayashi
keywords: Aspergillus; Invasive aspergillosis; Massive hemoptysis; Pulmonary bullae; Thoracic aorta