title: Accessing Benzimidazoles via a Ring Distortion Strategy: An Oxone Mediated Tandem Reaction of 2-Aminobenzylamines.
abstract: An exceptional oxone mediated tandem transformation of 2-aminobenzylamines to 2-substituted benzimidazoles is reported. It occurs at room temperature with aromatic, heteroaromatic, and aliphatic aldehydes. In this reaction initial condensation of 2-aminobenzylamine with appropriate aldehydes afforded a tetrahydroquinazoline intermediate which underwent oxone-mediated ring distortion to afford the desired compounds in moderate to excellent yields.
authors.affiliation: Department of Chemistry, School of Natural Sciences, Shiv Nadar University , Chithera, Dadri, Gautam Buddha Nagar, UP 201314, India.
authors.forename: Santanu
authors.initials: S
authors.lastname: Hati
authors.affiliation: Department of Chemistry, School of Natural Sciences, Shiv Nadar University , Chithera, Dadri, Gautam Buddha Nagar, UP 201314, India.
authors.forename: Pratip
authors.initials: P
authors.lastname: Kumar Dutta
authors.affiliation: Department of Chemistry, School of Natural Sciences, Shiv Nadar University , Chithera, Dadri, Gautam Buddha Nagar, UP 201314, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Dutta
authors.affiliation: Department of Chemistry, School of Natural Sciences, Shiv Nadar University , Chithera, Dadri, Gautam Buddha Nagar, UP 201314, India.
authors.forename: Parthapratim
authors.initials: P
authors.lastname: Munshi
authors.affiliation: Department of Chemistry, School of Natural Sciences, Shiv Nadar University , Chithera, Dadri, Gautam Buddha Nagar, UP 201314, India.
authors.forename: Subhabrata
authors.initials: S
authors.lastname: Sen