title: Efficacy and safety of spinning exercise in middle-aged and older adults with metabolic syndrome: randomized control trial.
abstract: BACKGROUND
  Few studies have been conducted to investigate the effects of spinning exercise on cardio-vascular weal.
  
  
  OBJECTIVE
  To assess whether a 6 months spinning training, combined with proper diet, is more effective than standard training programs and diet alone in improving metabolic abnormalities in middle-aged and older adults.
  
  
  METHODS
  Randomized clinical trial.
  
  
  METHODS
  Rehabilitation Unit of our Department.
  
  
  METHODS
  Patients with Metabolic Syndrome (MetS) according to the National Cholesterol Education Program Adult Treatment Panel III diagnostic criteria.
  
  
  METHODS
  Patients were randomly assigned to receive treatment with diet (group A, n = 10), with diet and general gymnastics program (group B, n = 10), with diet and spinning physical training program (group C, n = 10).
  
  
  RESULTS
  During the study period we observed a significant reduction in blood pressure (group C: systolic blood pressure p = 0.03; diastolic blood pressure p = 0.004 / group B: systolic blood pressure p = 0.001), in lipid profile (group B: plasma total cholesterol p = 0.001; triglycerides p = 0.001 / group C: plasma total cholesterol p = 0.04); in fasting blood glucose (group B: p = 0.01; group C: p = 0.008); in Homeostatic Model Assessment of Insulin Resistance (group B: p = 0.01; group C: p = 0.001); in waist circumference (group C: p = 0.005; group A: p = 0.02; group B: p = 0.04). No patients reported adverse events during follow-up.
  
  
  CONCLUSIONS
  Our results confirm the effectiveness of spinning training combined with diet in the management of MetS.
  
  
  CONCLUSIONS
  The findings provide a preliminary evidence to support that spinning training may represent a useful and safe intervention also in middle-aged and older adults geriatric with multiple CV risk factors.
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy.
authors.forename: Walter
authors.initials: W
authors.lastname: Verrusio
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Andreozzi
authors.affiliation: Dipartimento di Psicologia Dinamica e Clinica, Sapienza Università di Roma, Rome, Italy.
authors.forename: Alessia
authors.initials: A
authors.lastname: Renzi
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Martinez
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Longo
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Musumeci
authors.affiliation: Dipartimento di Scienze Cardiovascolari, Respiratorie, Nefrologiche, Anestesiologiche e Geriatriche, Sapienza Università di Roma, Rome, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Cacciafesta
mesh_terms: D000368:Aged; D001794:Blood Pressure; D004032:Diet; D005081:Exercise Therapy / Q000379:methods*; D005260:Female; D006801:Humans; D008055:Lipids / Q000097:blood; D008297:Male; D024821:Metabolic Syndrome / Q000178:diet therapy / Q000628:therapy*; D008875:Middle Aged; D016896:Treatment Outcome
chemical_list: D008055:Lipids