title: The use of augmentation techniques in osteoporotic fracture fixation.
abstract: There are an increasing number of fragility fractures, which present a surgical challenge given the reduced bone quality of underlying osteoporosis. Particularly in aged patients, there is a need for early weight bearing and mobilization to avoid further complications such as loss of function or autonomy. As an attempt to improve fracture stability and ultimate healing, the use of biomaterials for augmentation of osseous voids and fracture fixation is a promising treatment option. Augmentation techniques can be applied in various locations, and fractures of the metaphyseal regions such as proximal humerus, femur, tibia and the distal radius remain the most common areas for its use. The current review, based on the available mechanical and biological data, provides an overview of the relevant treatment options and different composites used for augmentation of osteoporotic fractures.
authors.affiliation: Department of Trauma Surgery, Munich University Hospital LMU, Nußbaumstr. 20, 80336Munich, Germany; Department of Trauma Surgery and Sportsmedicine, Medical University of Innsbruck, Anichstrasse 35, A-6020Innsbruck, Austria. Electronic address: christian.kammerlander@med.uni-muenchen.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Kammerlander
authors.affiliation: Department of Trauma Surgery, Munich University Hospital LMU, Nußbaumstr. 20, 80336Munich, Germany.
authors.forename: Carl
authors.initials: C
authors.lastname: Neuerburg
authors.affiliation: Department of Orthopaedics, University Medical Center Utrecht, Utrecht, The Netherlands.
authors.forename: Jorrit-Jan
authors.initials: JJ
authors.lastname: Verlaan
authors.affiliation: Department of Trauma Surgery and Sportsmedicine, Medical University of Innsbruck, Anichstrasse 35, A-6020Innsbruck, Austria.
authors.forename: Werner
authors.initials: W
authors.lastname: Schmoelz
authors.affiliation: Department of Orthopaedic Surgery, Orthopaedic Trauma Institute, San Francisco, University of California, San Francisco, San Francisco, CA, United States.
authors.forename: Theodore
authors.initials: T
authors.lastname: Miclau
authors.affiliation: Department of Orthopedics, Uppsala University Hospital, Uppsala, Sweden.
authors.forename: Sune
authors.initials: S
authors.lastname: Larsson
mesh_terms: D001843:Bone Cements; D001863:Bone Screws; D060826:Cementoplasty / Q000379:methods; D003131:Combined Modality Therapy; D005593:Fracture Fixation, Internal / Q000379:methods*; D017102:Fracture Healing; D006801:Humans; D010024:Osteoporosis / Q000150:complications / Q000000981:diagnostic imaging / Q000503:physiopathology*; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery*
chemical_list: D001843:Bone Cements
keywords: Augmentation; Biomaterials; Cement; Distal radius fracture; Fragility fractures; Hip fracture; Osteoporosis; Proximal tibia fracture; Vertebral fracture