title: [The relationship between group B streptococcus genital infection and premature rupture of membrane].
abstract: OBJECTIVE
  To investigate the relationship between the group B streptococcal (GBS) genital infection of the pregnant women and premature rupture of membrane (PROM).
  
  
  METHODS
  Five hundred and eighty seven cases in our hospital maternity clinic or hospital delivery of pregnant women were enrolled from October 2014 to December 2014, including 189 cases of pregnant women with PROM as the observation group and 398 cases of pregnant women without PROM as a control group.GBS in their rectum and vagina secretion was separated and tested by using Group B Streptococcus Chromogenic Agar.
  
  
  RESULTS
  Fifty eight cases were detected GBS positive in all 587 pregnant women.The positive rate was 9.9%.In 189 cases of PROM, 37 cases were GBS positive and the positive rate was 19.6%.While in 398 cases of normal pregnant women, 21 cases were positive and the positive rate was 5.3%.The difference has statistically significant (P<0.01).
  
  
  CONCLUSIONS
  GBS infection may be a risk factor for the occurrence of PROM.Psychological counseling, health education and antibiotics should be applied to the GBS positive pregnant women as a preventive strategy.
authors.affiliation: Department of Obstetrics and Gynecology of Nanjing Jiangning Hospital, Nanjing 211100, China.
authors.forename: J J
authors.initials: JJ
authors.lastname: Yan
authors.forename: M
authors.initials: M
authors.lastname: Gong
authors.forename: J
authors.initials: J
authors.lastname: Zhang
authors.forename: C B
authors.initials: CB
authors.lastname: Zhu
mesh_terms: D016022:Case-Control Studies; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000382:microbiology*; D006801:Humans; D007752:Obstetric Labor, Premature / Q000382:microbiology*; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000382:microbiology*; D011256:Pregnancy Outcome; D012007:Rectum; D012307:Risk Factors; D013290:Streptococcal Infections / Q000175:diagnosis*; D013292:Streptococcus agalactiae / Q000302:isolation & purification*; D014621:Vagina / Q000382:microbiology*