title: Oxidative stress markers in Thoroughbred horses after castration surgery under inhalation anesthesia.
abstract: Oxidative stress has been reported to occur during surgery. It is important to reduce intraoperative oxidative stress to improve the postoperative prognosis. However, there are no reports regarding oxidative stress related to surgery in horses. In the present study, we measured pre and postsurgical diacron-reactive oxygen metabolites (d-ROMs) and biological antioxidant potential (BAP); the oxidative stress index (OSI) was then calculated (OSI=d-ROMs/BAP × 100). d-ROMs were not significantly different between the pre and postsurgical periods. However, BAP significantly decreased after surgery (P=0.02), and OSI significantly increased after surgery (P=0.02). Based on these results, it suggested that castration surgery under inhalation anesthesia decreases the antioxidant potential and causes oxidative stress in horses.
authors.affiliation: Laboratory of Veterinary Surgery, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
authors.forename: Nao
authors.initials: N
authors.lastname: Tsuzuki
authors.affiliation: Department of Clinical Veterinary Science, Obihiro University of Agriculture and Veterinary Medicine, Hokkaido 080-8555, Japan.
authors.forename: Naoki
authors.initials: N
authors.lastname: Sasaki
authors.affiliation: Japan Racing Association Miho Training Center, Ibaraki 300-0493, Japan.
authors.forename: Kanichi
authors.initials: K
authors.lastname: Kusano
authors.affiliation: Japan Racing Association Miyazaki Yearling Training Farm, Miyazaki 880-0036, Japan.
authors.forename: Yoshiro
authors.initials: Y
authors.lastname: Endo
authors.affiliation: Veterinary Teaching Hospital, Faculty of Agriculture, University of Miyazaki, Miyazaki 889-2192, Japan.
authors.forename: Shidow
authors.initials: S
authors.lastname: Torisu
keywords: Thoroughbred; oxidative stress; surgery