title: One-Step Synthesis of Silver Nanoparticle-Decorated Hydroxyapatite Nanowires for the Construction of Highly Flexible Free-Standing Paper with High Antibacterial Activity.
abstract: A highly flexible and free-standing paper with high antibacterial activity made from silver nanoparticle (AgNP)-decorated ultralong hydroxyapatite nanowires (HAPNWs) is reported. The HAPNWs@AgNPs nanocomposites were obtained from a facile one-step solvothermal process and utilized for the construction of highly flexible and free-standing inorganic paper through a simple vacuum-filtration procedure. The structure and properties of the HAPNWs@AgNPs paper were characterized in detail. Scanning electron microscope (SEM) and transmission electron microscope (TEM) micrographs show that AgNPs are highly dispersed and stabilized in the nanocomposite and exhibit a narrow particle size distribution. The effects of the concentration of silver nitrate, solvothermal temperature and time on the product were systematically investigated. This method is simple, convenient and reproducible. The as-prepared HAPNWs@AgNPs paper shows long-time sustained silver-ion release, high antibacterial activity against both Gram-negative and Gram-positive bacteria, and good biocompatibility. Overall, this work provides a novel pathway for the preparation of a new type of highly flexible, free-standing and antibacterial inorganic paper made from silver nanoparticle-decorated hydroxyapatite nanowires for various applications, as a promising functional biomaterial.
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.
authors.forename: Zhi-Chao
authors.initials: ZC
authors.lastname: Xiong
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. y.j.zhu@mail.sic.ac.cn.
authors.forename: Ying-Jie
authors.initials: YJ
authors.lastname: Zhu
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.
authors.forename: Fei-Fei
authors.initials: FF
authors.lastname: Chen
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.
authors.forename: Tuan-Wei
authors.initials: TW
authors.lastname: Sun
authors.affiliation: State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China.
authors.forename: Yue-Qin
authors.initials: YQ
authors.lastname: Shen
mesh_terms: D000900:Anti-Bacterial Agents / Q000138:chemical synthesis* / Q000737:chemistry; D017886:Durapatite / Q000138:chemical synthesis* / Q000737:chemistry*; D006094:Gram-Positive Bacteria; D053768:Metal Nanoparticles / Q000737:chemistry*; D046529:Microscopy, Electron, Transmission; D053761:Nanocomposites / Q000737:chemistry*; D053770:Nanowires / Q000737:chemistry*; D012834:Silver / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D012834:Silver; D017886:Durapatite
keywords: free-standing paper; hydroxyapatite; nanoparticles; nanowires; silver