title: Low molecular weight heparin inhibits sickle erythrocyte adhesion to VCAM-1 through VLA-4 blockade in a standardized microfluidic flow adhesion assay.
authors.affiliation: Wayne State University School of Medicine, Detroit, MI, USA.|Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA.
authors.forename: Moira
authors.initials: M
authors.lastname: Lancelot
authors.affiliation: Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI, USA.
authors.forename: Jennell
authors.initials: J
authors.lastname: White
authors.affiliation: Wayne State University School of Medicine, Detroit, MI, USA.|Division of Pediatric Hematology/Oncology, Children's Hospital of Michigan, Detroit, MI, USA.|Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI, USA.
authors.forename: Sharada
authors.initials: S
authors.lastname: Sarnaik
authors.affiliation: Carman and Ann Adams Department of Pediatrics, Children's Hospital of Michigan, Detroit, MI, USA.|Division of Pediatric Critical Care Medicine, Children's Hospital of Michigan, Detroit, MI, USA.|Department of Physiology, Wayne State University School of Medicine, Detroit, MI, USA.
authors.forename: Patrick
authors.initials: P
authors.lastname: Hines
mesh_terms: D000755:Anemia, Sickle Cell / Q000097:blood / Q000378:metabolism; D002448:Cell Adhesion / Q000187:drug effects; D004913:Erythrocytes, Abnormal / Q000187:drug effects* / Q000378:metabolism*; D006495:Heparin, Low-Molecular-Weight / Q000494:pharmacology*; D006801:Humans; D039041:Integrin alpha4beta1 / Q000037:antagonists & inhibitors* / Q000378:metabolism*; D044085:Microfluidics / Q000379:methods*; D011485:Protein Binding; D019010:Vascular Cell Adhesion Molecule-1 / Q000378:metabolism*
chemical_list: D006495:Heparin, Low-Molecular-Weight; D039041:Integrin alpha4beta1; D019010:Vascular Cell Adhesion Molecule-1
keywords: VLA-4; adhesion; erythrocytes; low molecular weight heparin; sickle cell disease