title: Relationship Between Common Mental Disorder Symptoms During Pregnancy and Preterm Birth Among Chinese Women in Wuhan.
abstract: Objectives Few studies focus on the symptoms of common mental disorders during pregnancy (CMDP) and risk of preterm birth subtypes (PTB). The purpose of this study was to estimate the association between CMDP and PTB, and to examine whether or not the association between CMDP and PTB varies with the subtype of PTB in Chinese. Methods This population-based case control study, conducted in Wuhan, China, defined cases as every pregnant woman who had a PTB among all births in Wuhan, from June 10, 2011, to June 9, 2013. The same number of pregnant women who had term births was randomly selected as controls. The Electronic Perinatal Health Care Information System, a questionnaire designed for the study, provided data about the participants. Logistic regression analyses were used to model associations between CMDP and PTB, and to test associations between CMDP and two subtypes of PTB. Results The study recruited 8616 cases and an equal number of controls. We successfully collected maternal information on 6656 cases and controls for a response rate of 77.3 %. The incidence of PTB in Wuhan was 4.5 %. Spontaneous preterm births (SPTB) accounted for 60.1 %, and medically induced preterm births (IPTB) accounted for 39.9 % of preterm births. The prevalence rate of CMDP was 15.8 %. CMDP was slightly associated with PTB (crude OR 1.16, 95 % CI 1.01-1.32; adjusted OR 1.15, 95 % CI 1.00-1.32), further analyses showed CMDP was associated with IPTB (aOR 1.25, 95 % CI 1.04-1.50), but not with SPTB. Conclusion Our data suggest that CMDP is related to an increased risk of PTB, and that this association is primarily due to IPTB rather than SPTB.
authors.affiliation: Wuhan Medical and Health Center for Women and Children, 100 Hongkong Road, Jiangan District, Wuhan, 430015, China.
authors.forename: Rong
authors.initials: R
authors.lastname: Yang
authors.affiliation: Wuhan Environmental Monitoring Center, 422 Xinhua Road, Wuhan, 430015, China.
authors.forename: Shengwen
authors.initials: S
authors.lastname: Liang
authors.affiliation: Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA.
authors.forename: Louise H
authors.initials: LH
authors.lastname: Flick
authors.affiliation: Wuhan Medical and Health Center for Women and Children, 100 Hongkong Road, Jiangan District, Wuhan, 430015, China.
authors.forename: Shaoping
authors.initials: S
authors.lastname: Yang
authors.affiliation: Wuhan Environmental Monitoring Center, 422 Xinhua Road, Wuhan, 430015, China.
authors.forename: Ke
authors.initials: K
authors.lastname: Hu
authors.affiliation: Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA.
authors.forename: Jing
authors.initials: J
authors.lastname: Wang
authors.affiliation: Wuhan Medical and Health Center for Women and Children, 100 Hongkong Road, Jiangan District, Wuhan, 430015, China.
authors.forename: Ronghua
authors.initials: R
authors.lastname: Hu
authors.affiliation: Wuhan Environmental Monitoring Center, 422 Xinhua Road, Wuhan, 430015, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Huang
authors.affiliation: School of Public Health, Sun Yat-Sen University, 135 Xingang Xi Road, Guangzhou, 510275, China.
authors.forename: Guanghui
authors.initials: G
authors.lastname: Dong
authors.affiliation: Wuhan Environmental Monitoring Center, 422 Xinhua Road, Wuhan, 430015, China.
authors.forename: Yiming
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Wuhan Environmental Monitoring Center, 422 Xinhua Road, Wuhan, 430015, China.
authors.forename: Longjiao
authors.initials: L
authors.lastname: Shen
authors.affiliation: Wuhan Medical and Health Center for Women and Children, 100 Hongkong Road, Jiangan District, Wuhan, 430015, China.
authors.forename: Anna
authors.initials: A
authors.lastname: Peng
authors.affiliation: Public Health School, Brown University, 121 South Main Street, Providence, RI, 02912, USA.
authors.forename: Tongzhang
authors.initials: T
authors.lastname: Zheng
authors.affiliation: Tongji Medical College, Huazhong University of Science and Technology, 13 Hang Kong Lu, Wuhan, 430030, China.
authors.forename: Shunqing
authors.initials: S
authors.lastname: Xu
authors.affiliation: Wuhan Medical and Health Center for Women and Children, 100 Hongkong Road, Jiangan District, Wuhan, 430015, China. mchwhzb@163.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Zhang
authors.affiliation: Department of Epidemiology, College for Public Health and Social Justice, Saint Louis University, 3545 Lafayette Avenue, Saint Louis, MO, 63104, USA. zqian2@slu.edu.
authors.forename: Zhengmin
authors.initials: Z
authors.lastname: Qian
mesh_terms: D000328:Adult; D001007:Anxiety / Q000175:diagnosis / Q000208:ethnology* / Q000523:psychology; D044466:Asian People / Q000208:ethnology / Q000706:statistics & numerical data*; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D015331:Cohort Studies; D003863:Depression / Q000175:diagnosis / Q000208:ethnology* / Q000523:psychology; D005260:Female; D006801:Humans; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D011159:Population Surveillance; D011247:Pregnancy; D037841:Pregnant People / Q000208:ethnology / Q000523:psychology*; D047928:Premature Birth / Q000208:ethnology*; D012307:Risk Factors; D055815:Young Adult
keywords: Common mental disorders during pregnancy; Medically induced preterm births; Preterm birth; Spontaneous preterm births PTB