title: Copper-mediated arylation with arylboronic acids: Facile and modular synthesis of triarylmethanes.
abstract: A facile and modular synthesis of triarylmethanes was achieved in good yield via a two-step sequence in which the final step is the copper(II)-catalyzed arylation of diarylmethanols with arylboronic acids. By using this protocol a variety of symmetrical and unsymmetrical triarylmethanes were synthesized. As an application of the newly developed methodology, we demonstrate a high-yielding synthesis of the triarylmethane intermediate towards an anti-breast-cancer drug candidate.
authors.affiliation: Department of Chemistry, Pondicherry University, Pondicherry 605 014, India Telephone: +914132654411;
authors.forename: H Surya Prakash
authors.initials: HS
authors.lastname: Rao
authors.affiliation: Department of Chemistry, Pondicherry University, Pondicherry 605 014, India Telephone: +914132654411;
authors.forename: A Veera Bhadra
authors.initials: AV
authors.lastname: Rao
keywords: copper; modular synthesis; triarylmethanes