title: Supportive peri-implant therapy following anti-infective surgical peri-implantitis treatment: 5-year survival and success.
abstract: OBJECTIVE
  To evaluate clinical outcomes of supportive peri-implant therapy (SPIT) following surgical treatment of peri-implantitis.
  
  
  METHODS
  Twenty-four partially dentate patients with 36 dental implants diagnosed with peri-implantitis were treated by an anti-infective surgical protocol followed by regular supportive therapy. SPIT included removal of supra- and submucosal biofilm at the treated implants using titanium or carbon fibre curettes, or ultrasonic devices. In addition, professional prophylaxis (calculus/biofilm removal) at other implants/teeth and oral hygiene reinforcement was provided. Clinical measurements and radiographs were obtained at 1, 3 and 5 years. A successful treatment outcome was defined as implant survival with the absence of peri-implant probing depths (PD) ≥ 5 mm with concomitant bleeding/suppuration and absence of progression of peri-implant bone loss.
  
  
  RESULTS
  Twelve months after treatment, there was 100% survival of the treated implants and 79% of patients (19 of 24) had a successful treatment outcome according to the defined success criteria. At 3 years, 75% of the patients (18 of 24) had a successful treatment outcome, two patients (8%) were lost to follow-up (LTF), while 8% lost an implant, and two patients had recurrence of peri-implantitis. Between 3 and 5 years, an additional two patients were LTF, and an additional two patients each lost one implant. Thus, at 5 years 63% of patients (15 of 24) had a successful treatment outcome. Complete resolution of peri-implantitis, defined as absence of bleeding at all sites, was achieved in 42% of implants (N = 15) at 5 years.
  
  
  CONCLUSIONS
  Five years following regular supportive therapy, the peri-implant conditions established following peri-implantitis surgery were maintained in the majority of patients and implants. Some patients had recurrence of peri-implantitis and some lost implants over the 5-year period.
authors.affiliation: International Research Collaborative, Faculty of Science, The University of Western Australia, Perth, WA, Australia.|Perth Periodontal Specialists, Perth, WA, Australia.
authors.forename: Lisa J A
authors.initials: LJA
authors.lastname: Heitz-Mayfield
authors.affiliation: School of Dental Medicine, The University of Bern, Bern, Switzerland.
authors.forename: Giovanni E
authors.initials: GE
authors.lastname: Salvi
authors.affiliation: School of Dental Medicine, The University of Geneva, Geneva, Switzerland.
authors.forename: Andrea
authors.initials: A
authors.lastname: Mombelli
authors.affiliation: School of Dental Medicine, The University of Geneva, Geneva, Switzerland.
authors.forename: Pierre-Jean
authors.initials: PJ
authors.lastname: Loup
authors.affiliation: Perth Periodontal Specialists, Perth, WA, Australia.
authors.forename: Fritz
authors.initials: F
authors.lastname: Heitz
authors.affiliation: International Research Collaborative, Faculty of Science, The University of Western Australia, Perth, WA, Australia.
authors.forename: Estie
authors.initials: E
authors.lastname: Kruger
authors.affiliation: Center for Dental Medicine, University of Zurich, Zurich, Switzerland.
authors.forename: Niklaus P
authors.initials: NP
authors.lastname: Lang
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use; D018441:Biofilms; D001862:Bone Resorption / Q000000981:diagnostic imaging / Q000601:surgery; D003131:Combined Modality Therapy; D015921:Dental Implants / Q000009:adverse effects*; D019232:Dental Restoration Failure; D006801:Humans; D016015:Logistic Models; D057873:Peri-Implantitis / Q000000981:diagnostic imaging / Q000188:drug therapy / Q000601:surgery*; D011446:Prospective Studies; D011861:Radiography, Dental; D012008:Recurrence; D016019:Survival Analysis
chemical_list: D000890:Anti-Infective Agents; D015921:Dental Implants
keywords: maintenance care; peri-implantitis; success; supportive therapy; survival