title: Dual Photoredox/Gold Catalysis Arylative Cyclization of o-Alkynylphenols with Aryldiazonium Salts: A Flexible Synthesis of Benzofurans.
abstract: A new method for the arylative cyclization of o-alkynylphenols with aryldiazonium salts via dual photoredox/gold catalysis is described. The reaction proceeds smoothly at room temperature in the absence of base and/or additives and offers an efficient approach to benzofuran derivatives. The scope of the transformation is wide, and the limitations are discussed. The reaction is proposed to proceed through a photoredox-promoted generation of a vinylgold(III) intermediate that undergoes reductive elimination to provide the heterocyclic coupling adduct.
authors.affiliation: Sorbonne Universités UPMC Univ Paris 06, CNRS, UMR 8232, Institut Parisien de Chimie Moléculaire, 4 place Jussieu, C.229, F-75005 Paris, France.
authors.forename: Zhonghua
authors.initials: Z
authors.lastname: Xia
authors.affiliation: Sorbonne Universités UPMC Univ Paris 06, CNRS, UMR 8232, Institut Parisien de Chimie Moléculaire, 4 place Jussieu, C.229, F-75005 Paris, France.
authors.forename: Omar
authors.initials: O
authors.lastname: Khaled
authors.affiliation: Sorbonne Universités UPMC Univ Paris 06, CNRS, UMR 8232, Institut Parisien de Chimie Moléculaire, 4 place Jussieu, C.229, F-75005 Paris, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Mouriès-Mansuy
authors.affiliation: Sorbonne Universités UPMC Univ Paris 06, CNRS, UMR 8232, Institut Parisien de Chimie Moléculaire, 4 place Jussieu, C.229, F-75005 Paris, France.
authors.forename: Cyril
authors.initials: C
authors.lastname: Ollivier
authors.affiliation: Sorbonne Universités UPMC Univ Paris 06, CNRS, UMR 8232, Institut Parisien de Chimie Moléculaire, 4 place Jussieu, C.229, F-75005 Paris, France.
authors.forename: Louis
authors.initials: L
authors.lastname: Fensterbank