title: Commentary: A Humanized Clinically Calibrated Quantitative Systems Pharmacology Model for Hypokinetic Motor Symptoms in Parkinson's Disease.
authors.affiliation: Molecular and Clinical Pharmacology, Faculty of Medicine, University of Chile Santiago, Chile.
authors.forename: Patricia
authors.initials: P
authors.lastname: Muñoz
authors.affiliation: Molecular and Clinical Pharmacology, Faculty of Medicine, University of Chile Santiago, Chile.
authors.forename: Juan
authors.initials: J
authors.lastname: Segura-Aguilar
keywords: alpha-synuclein oligomers; aminocromo; dopamine oxidation; mitochondrial dysfunction; neuromelanin; neuronal dysfunction; preclinical models; protein degradation dysfunction