title: The epidemiology, prevalence and hospital outcomes of infants with gastroschisis.
abstract: The purpose of this study is to evaluate recent trends in prevalence of gastroschisis among infants admitted for neonatal intensive care in the United States.
  
  
  
  Retrospective review of a de-identified patient data. The current study extends our observations through the end of 2007 to 2015.
  
  
  
  During the study period (1 January 1997 to 12 December 2015), there were 1 158 755 total discharges; 6023 (5.2/1000) had gastroschisis and 1885 (1.6/1000) had an omphalocele. Between 1997 and 2008, the reported rate of gastroschisis increased from 2.9 to 6.4/1000 discharges. From 2008 to 2011, the values have slowly decreased from 6.4 to 4.7/1000 discharges and since 2011 have been stable. The largest drop in the prevalence was in mothers who were <20 years old. In contrast, the reported rate of omphalocele was stable at 1 to 2/1000 discharges.
  
  
  
  The prevalence of gastroschisis increased from 1997 to 2008, and then declined thereafter.
authors.affiliation: Herbert Wertheim College of Medicine, Florida International University, Miami, FL, USA.
authors.forename: R
authors.initials: R
authors.lastname: Allman
authors.affiliation: Department of Biomedical Sciences, Charles E. Schmidt College of Medicine, Florida Atlantic University, Boca Raton, FL, USA.
authors.forename: J
authors.initials: J
authors.lastname: Sousa
authors.affiliation: Division of Neonatology, Greenville Health System, University of South Carolina School of Medicine-Greenville, Greenville, SC, USA.
authors.forename: M W
authors.initials: MW
authors.lastname: Walker
authors.affiliation: Division of Neonatal-Perinatal Medicine, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
authors.forename: M M
authors.initials: MM
authors.lastname: Laughon
authors.affiliation: The Pediatrix Center for Research, Education, and Quality, MEDNAX, Inc., Sunrise, FL, USA.
authors.forename: A R
authors.initials: AR
authors.lastname: Spitzer
authors.affiliation: The Pediatrix Center for Research, Education, and Quality, MEDNAX, Inc., Sunrise, FL, USA.
authors.forename: R H
authors.initials: RH
authors.lastname: Clark
mesh_terms: D000293:Adolescent; D000328:Adult; D005260:Female; D020139:Gastroschisis / Q000453:epidemiology*; D006554:Hernia, Umbilical / Q000453:epidemiology*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D007363:Intensive Care Units, Neonatal / Q000706:statistics & numerical data; D016015:Logistic Models; D008423:Maternal Age; D011247:Pregnancy; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D014481:United States / Q000453:epidemiology; D055815:Young Adult