title: Effects of leukocyte-platelet rich fibrin on postoperative complications of direct sinus lifting.
abstract: BACKGROUND
  Blood products have been widely used in soft tissue and bone regeneration in oral and maxillofacial surgery. The purpose of this study is to evaluate the effects of leukocyte-platelet rich fibrin (L-PRF) following direct sinus lifting procedure.
  
  
  METHODS
  Twenty-eight patients were included in the study. Direct sinus lifting was performed via lateral window approach under conscious sedation and local anesthesia. Bony window and sinus floor elevation were performed using piezosurgery device. Two groups were formed. In the first group an allogenous bone graft and L-PRF mixture was used as grafting material. The L-PRF membrane was used to close the lateral window. In the second group, only allogenous bone was used for grafting and resorbable collagen membrane was used to close the lateral window. Pain, swelling, sleeping, eating, phonetics, activities of daily living, missed work days and soft tissue healing were evaluated postoperatively.
  
  
  RESULTS
  Data of 24 patients were evaluated. Improvements were seen in the studied parameters in the L-PRF group; however, the difference was not significant between the two groups (P>0.05).
  
  
  CONCLUSIONS
  The use of L-PRF and allogenous bone graft in combination with L-PRF membrane does not significantly improve postoperative complications following direct sinus lifting.
authors.affiliation: Istanbul Medipol University School of Dentistry, Department of Oral and Maxillofacial Surgery, Unkapani, Istanbul, Turkey - ggurler@medipol.edu.tr.
authors.forename: Gokhan
authors.initials: G
authors.lastname: Gurler
authors.forename: Cagri
authors.initials: C
authors.lastname: Delilbasi
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D000368:Aged; D001184:Articulation Disorders / Q000209:etiology / Q000628:therapy; D001792:Blood Platelets; D004487:Edema / Q000209:etiology / Q000628:therapy; D005260:Female; D005337:Fibrin / Q000627:therapeutic use*; D006801:Humans; D036341:Intercellular Signaling Peptides and Proteins / Q000008:administration & dosage / Q000627:therapeutic use; D007962:Leukocytes; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000209:etiology / Q000628:therapy*; D059546:Sinus Floor Augmentation; D014945:Wound Healing; D055815:Young Adult
chemical_list: D036341:Intercellular Signaling Peptides and Proteins; D005337:Fibrin