title: Treatment of Recurrent Disc Herniation: A Systematic Review.
abstract: Intervertebral disc herniation is one of the most common causes of back and extremity pain. The most commonly used surgical treatment is lumbar discectomy. About 0.5-25% go on to develop recurrent disc herniation (rDH) after a successful first discectomy. Currently, there aren't any guidelines to assist surgeons in determining which approach is most appropriate to treat rDH. A recent survey showed significant heterogeneity among surgeons regarding treatment options for rDH. It remains unclear which methods lead to better outcomes, as there are no comparative studies with a sufficient level of evidence. In this study, we aimed to perform a systematic review to compare treatment options for rDH and determine if one intervention provides better outcomes than the other; more specifically, whether outcome differences exist between discectomy alone and discectomy with fusion. We applied the PICOS (participants, intervention, comparison, outcome, study design) format to develop this systematic review through PubMed. Twenty-seven papers from 1978-2014 met our inclusion criteria and were included in the analysis. Nine papers reported outcomes after discectomy and seven of them showed good or excellent outcomes (70.60%-89%). Ten papers reported on minimally invasive discectomy. The percent change in visual analog scale (VAS) ranged from -50.77% to -86.57%, indicating an overall pain reduction. Four studies out of the ten reported good or excellent outcomes (81% to 90.2%). Three studies looked at posterolateral fusion. Three studies analyzed posterior lumbar interbody fusion. For one study, we found the VAS percentage change to be -46.02%. All reported good to excellent outcomes. Six studies evaluated the transforaminal lumbar interbody fusion. All reported improvement in pain. Four used VAS, and we found the percent change to be -54% to -86.5%. The other two used the Japanese Orthopedic Association (JOA) score, and we found the percent change to be 68.3% to 93.3%. We did not find enough evidence to support any significant difference in outcomes between discectomy alone and discectomy with fusion. The limitation of our study includes the lack of standardized outcomes reporting in the literature. However, reviewing the selected articles shows that fusion may have a greater improvement in pain compared to reoperation without fusion. Nonetheless, our study shows that further and more in-depth investigation is needed on the of treatment of rDH.
authors.affiliation: Department of Neurosurgery, Cedars-Sinai Medical Center.
authors.forename: Doniel
authors.initials: D
authors.lastname: Drazin
authors.affiliation: Department of Neurosurgery, University of Louisville.
authors.forename: Beatrice
authors.initials: B
authors.lastname: Ugiliweneza
authors.affiliation: Department of Neurosurgery, Cedars-Sinai Medical Center.
authors.forename: Lutfi
authors.initials: L
authors.lastname: Al-Khouja
authors.affiliation: Department of Epidemiology and Population Health, University of Louisville.
authors.forename: Dongyan
authors.initials: D
authors.lastname: Yang
authors.affiliation: Department of Neurosurgery, Cedars-Sinai Medical Center.
authors.forename: Patrick
authors.initials: P
authors.lastname: Johnson
authors.affiliation: Deparment of Orthopedics, Cedars-Sinai Medical Center.
authors.forename: Terrence
authors.initials: T
authors.lastname: Kim
authors.affiliation: Department of Neurosurgery, University of Louisville.
authors.forename: Maxwell
authors.initials: M
authors.lastname: Boakye
keywords: back pain; interbody fusion; minimally invasive lumbar fusion; recurrent disc herniation; recurrent lumbar disc herniation; revision fusion; spinal fusion; spine