title: Malignant priapism due to penile metastases: Case series and literature review.
abstract: Malignant priapism secondary to penile metastases is a rare condition. This term was originally used by Peacock in 1938 to describe a condition of painful induration and erection of the penis due to metastatic infiltration by a neoplasm. In the current literature there are 512 case reports. The primary tumor sites are bladder, prostate and rectum. The treatment has only palliative intent and consists of local tumor excision, penectomy, radiotherapy and chemotherapy. We present one case of malignant priapism originated from prostate cancer, and two from urothelial carcinoma of the bladder. Different approaches in diagnosis and therapy were performed. The entire three patient reported a relief of the pain following the treatment, with an improvement of their quality of life, even though it was only temporary as a palliative. Malignant priapism is a rare medical emergency. Penile/pelvis magnetic resonance imaging (MRI) scan and corporal biopsies are considered an effective method of diagnosis of the primary organ site.
authors.affiliation: St Peter's Andrology and the Insitute of Urology, University College London Hospital, London. francescodeluca10@gmail.com.
authors.forename: Francesco
authors.initials: F
authors.lastname: De Luca
authors.forename: Evangelos
authors.initials: E
authors.lastname: Zacharakis
authors.forename: Majed
authors.initials: M
authors.lastname: Shabbir
authors.forename: Angela
authors.initials: A
authors.lastname: Maurizi
authors.forename: Emy
authors.initials: E
authors.lastname: Manzi
authors.forename: Antonio
authors.initials: A
authors.lastname: Zanghì
authors.forename: Carlo
authors.initials: C
authors.lastname: De Dominicis
authors.forename: David
authors.initials: D
authors.lastname: Ralph
mesh_terms: D000368:Aged; D002295:Carcinoma, Transitional Cell / Q000000981:diagnostic imaging / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008875:Middle Aged; D010412:Penile Neoplasms / Q000150:complications* / Q000556:secondary / Q000628:therapy; D011317:Priapism / Q000209:etiology*; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology; D011788:Quality of Life; D001749:Urinary Bladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology