title: Mobile health: the power of wearables, sensors, and apps to transform clinical trials.
abstract: Mobile technology has become a ubiquitous part of everyday life, and the practical utility of mobile devices for improving human health is only now being realized. Wireless medical sensors, or mobile biosensors, are one such technology that is allowing the accumulation of real-time biometric data that may hold valuable clues for treating even some of the most devastating human diseases. From wearable gadgets to sophisticated implantable medical devices, the information retrieved from mobile technology has the potential to revolutionize how clinical research is conducted and how disease therapies are delivered in the coming years. Encompassing the fields of science and engineering, analytics, health care, business, and government, this report explores the promise that wearable biosensors, along with integrated mobile apps, hold for improving the quality of patient care and clinical outcomes. The discussion focuses on groundbreaking device innovation, data optimization and validation, commercial platform integration, clinical implementation and regulation, and the broad societal implications of using mobile health technologies.
authors.affiliation: FasterCures, Milken Institute, Washington, DC.
authors.forename: Bernard
authors.initials: B
authors.lastname: Munos
authors.affiliation: FierceBigData, Questex Media Group, LLC.
authors.forename: Pamela C
authors.initials: PC
authors.lastname: Baker
authors.affiliation: Sage Bionetworks, Seattle, Washington.
authors.forename: Brian M
authors.initials: BM
authors.lastname: Bot
authors.affiliation: GlaxoSmithKline, Collegeville, Pennsylvania.
authors.forename: Michelle
authors.initials: M
authors.lastname: Crouthamel
authors.affiliation: Medidata Solutions, New York, New York.
authors.forename: Glen
authors.initials: G
authors.lastname: de Vries
authors.affiliation: ARM, San Francisco, California.
authors.forename: Ian
authors.initials: I
authors.lastname: Ferguson
authors.affiliation: Department of Neurology, University of California, San Francisco, and San Francisco VA Medical Center, San Francisco, California.
authors.forename: John D
authors.initials: JD
authors.lastname: Hixson
authors.affiliation: Healthcare and Privacy & Cybersecurity Practices, Moses & Singer, LLP, New York, New York.
authors.forename: Linda A
authors.initials: LA
authors.lastname: Malek
authors.affiliation: Medtronic PLC, Los Angeles, California.
authors.forename: John J
authors.initials: JJ
authors.lastname: Mastrototaro
authors.affiliation: The NSF Nanosystems Engineering Research Center (NERC) for Advanced Self-Powered Systems of Integrated Sensors and Technologies (ASSIST), North Carolina State University, Raleigh, North Carolina.
authors.forename: Veena
authors.initials: V
authors.lastname: Misra
authors.affiliation: California NanoSystems Institute and Departments of Bioengineering and Electrical Engineering, University of California, Los Angeles, California.
authors.forename: Aydogan
authors.initials: A
authors.lastname: Ozcan
authors.affiliation: U.S. Food and Drug Administration, Silver Spring, Maryland.
authors.forename: Leonard
authors.initials: L
authors.lastname: Sacks
authors.affiliation: Icahn School of Medicine at Mount Sinai, New York, New York.
authors.forename: Pei
authors.initials: P
authors.lastname: Wang
mesh_terms: D015374:Biosensing Techniques; D002986:Clinical Trials as Topic; D006801:Humans; D063731:Mobile Applications / Q000331:legislation & jurisprudence; D011634:Public Health; D017216:Telemedicine / Q000331:legislation & jurisprudence; D013686:Telemetry
keywords: biosensors; clinical study; data; health care; medical device; mobile technology; wireless