title: Hypervalent Iodine(III) Mediated Synthesis of 3-Substituted 5-Amino-1,2,4-thiadiazoles through Intramolecular Oxidative S-N Bond Formation.
abstract: An efficient synthesis of 3-substituted-5-arylamino-1,2,4-thiadiazoles through intramolecular oxidative S-N bond formation of imidoyl thioureas by phenyliodine(III) bis(trifluoroacetate) is reported. The protocol features a metal-free approach, broad substrate scope, very short reaction times, good to excellent yields, and simple starting materials.
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai 625 021, India.
authors.forename: Arumugam
authors.initials: A
authors.lastname: Mariappan
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai 625 021, India.
authors.forename: Kandasamy
authors.initials: K
authors.lastname: Rajaguru
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai 625 021, India.
authors.forename: Noufal
authors.initials: N
authors.lastname: Merukan Chola
authors.affiliation: Department of Organic Chemistry, School of Chemistry, Madurai Kamaraj University , Madurai 625 021, India.
authors.forename: Shanmugam
authors.initials: S
authors.lastname: Muthusubramanian
authors.affiliation: X-ray Diffraction Laboratory, Department of Chemistry, Texas A&M University , College Station, Texas 77842, United States.
authors.forename: Nattamai
authors.initials: N
authors.lastname: Bhuvanesh