title: Temporary Percutaneous Mechanical Circulatory Support in Advanced Heart Failure.
abstract: Cardiogenic shock is severe, refractory heart failure caused by significant myocardial dysfunction in the setting of adequate preload that is accompanied by systemic hypoperfusion. Progressive end-organ dysfunction is a hallmark of persistent cardiogenic shock and necessitates intervention to overcome altered hemodynamics and restore end-organ perfusion. Temporary percutaneous mechanical circulatory support is an established modality in the treatment of cardiogenic shock and is increasingly used in patients with cardiogenic shock as a bridge to recovery or further definitive therapy. This article reviews the current devices, their effects on left ventricular hemodynamics, and the evidence supporting their continued use.
authors.affiliation: Houston Methodist Hospital, 6550 Fannin Street, Suite 1901, Houston, TX 77030, USA.
authors.forename: Jessica L
authors.initials: JL
authors.lastname: Brown
authors.affiliation: Heart Transplant & LVAD Program, Division of Heart Failure, Houston Methodist Institute of Academic Medicine, Methodist DeBakey Heart & Vascular Center, Houston Methodist Hospital, 6550 Fannin Street, Suite 1901, Houston, TX 77030, USA. Electronic address: jestep@houstonmethodist.org.
authors.forename: Jerry D
authors.initials: JD
authors.lastname: Estep
mesh_terms: D001243:Assisted Circulation / Q000295:instrumentation* / Q000379:methods; D002986:Clinical Trials as Topic; D006333:Heart Failure / Q000503:physiopathology* / Q000601:surgery; D006353:Heart-Assist Devices; D006439:Hemodynamics / Q000502:physiology; D006801:Humans; D012770:Shock, Cardiogenic / Q000503:physiopathology / Q000601:surgery*; D016896:Treatment Outcome
keywords: Cardiogenic shock; ECMO; IABP; Impella; Percutaneous mechanical circulatory support; Pressure-volume loop; TandemHeart