title: Crystal structure of a bioactive sesquiterpene isolated from Artemisia reticulata.
abstract: The title compound, C15H24O2 {systematic name: 1-[6-hy-droxy-7-(propan-2-yl)-4-methyl-idene-2,3,3a,4,5,6,7,7a-octa-hydro-1H-inden-1-yl]ethanone} was iso-la-ted from A. reticulata by column chromatography over silica gel by gradient solvent elution. The mol-ecule comprises a bi-cyclo-[4.3.0]nonane ring bearing acet-oxy, hy-droxy and isopropyl substituents, and an exocyclic double bond on the cyclo-hexane ring. In the bicyclic skeleton, the cyclo-hexane ring adopts a chair conformation ring and the cyclo-pentane ring is in an envelope conformation. In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, forming chains along [010]. These chains are cross-linked by C-H⋯O hydrogen bonds.
authors.affiliation: Bioorganic Division, Bhabha Atomic Research Centre, Trombay, Mumbai 85, India.
authors.forename: A K
authors.initials: AK
authors.lastname: Bauri
authors.affiliation: Clemens Schöpf-Institut für Organische, Chemie und Biochemie, Technische Universität Darmstadt, Petersenstrasse 22, D-64287 Darmstadt, Germany.
authors.forename: Sabine
authors.initials: S
authors.lastname: Foro
authors.affiliation: Accident & Emergency Department, Franco, Vietnamese Hospital, 7-Nguyen, Luong Bang Street, HoChiMinh City, Vietnam.
authors.forename: Nhu Quynh Nguyen
authors.initials: NQ
authors.lastname: Do
keywords: Artemisia reticulata; anti­proliferative property; crystal structure; isolation; sesquiterpene