title: Transition-metal-free oxychlorination of alkenyl oximes: in situ generated radicals with tert-butyl nitrite.
abstract: Oxychlorination of alkenyl oximes is harder compared to the analogous oxybromination or oxyiodination because of the difficulty associated with the formation of chlorine cations or radicals. A transition-metal-free oxychlorination of alkenyl oximes has been developed, using t-BuONO as a dual oxidant and AlCl3 as a chlorine source. This convenient and practical method has been used to construct chloroisoxazolines in moderate to good yields, whereas N-chlorosuccinimide (NCS) failed to promote this reaction.
authors.affiliation: Center of Advanced Nanocatalysis, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. ybkang@ustc.edu.cn.
authors.forename: Xiao-Wei
authors.initials: XW
authors.lastname: Zhang
authors.affiliation: Center of Advanced Nanocatalysis, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. ybkang@ustc.edu.cn.
authors.forename: Zu-Feng
authors.initials: ZF
authors.lastname: Xiao
authors.affiliation: Center of Advanced Nanocatalysis, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. ybkang@ustc.edu.cn.
authors.forename: Mei-Mei
authors.initials: MM
authors.lastname: Wang
authors.affiliation: Center of Advanced Nanocatalysis, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. ybkang@ustc.edu.cn.
authors.forename: Yan-Jun
authors.initials: YJ
authors.lastname: Zhuang
authors.affiliation: Center of Advanced Nanocatalysis, Department of Chemistry, University of Science and Technology of China, Hefei, Anhui 230026, China. ybkang@ustc.edu.cn.
authors.forename: Yan-Biao
authors.initials: YB
authors.lastname: Kang