title: Biophysical and biological perspective in biosemiotics.
abstract: The cell and its basic constituents are introduced here through a biophysical and information communication theoretic approach in biology and biosemiotics. With this purpose, the requirements of primordial cellular structures, single binding events, and signalling cascades are first mentioned stepwise, in relation to the model of the cellular sensing mechanism. This is followed by the concepts of cross reactions in sensing and pattern recognitions, wherein an information theoretic approach is addressed and the features of multicellularity are discussed along. Multicellularity is introduced as the path that leads to the loss of the direct causal relations. The loss of true causal relation is considered as a form of translation that enables meaning-encoded communication over the informative processes. In this sense, semiosis may not be exclusive. Synthetic biology is exemplified as a form of artificial selection mechanisms for the generation of 'self-reproducing' systems with information coding and processing machineries. These discussions are summarised at the end.
authors.affiliation: Department of Biophysics, School of Medicine, Istanbul Kemerburgaz University, Kartaltepe Mahallesi Incirli Caddesi No: 11, 34147 Bakirkoy, Istanbul, Turkey. Electronic address: yekbun.adiguzel@kemerburgaz.edu.tr.
authors.forename: Yekbun
authors.initials: Y
authors.lastname: Adiguzel
mesh_terms: D000818:Animals; D001695:Biology / Q000379:methods*; D001703:Biophysics / Q000379:methods*; D006801:Humans; D015398:Signal Transduction
keywords: Biosemiotics; Cell; Communication; Molecular biophysics; Signalling