title: Roles of Chinese herbal medicines in ischemic heart diseases (IHD) by regulating oxidative stress.
abstract: Ischemic heart disease (IHD) basing on atherosclerosis (AS) is known as a top killer for decades. Oxidative stress, representing excessive oxidation and insufficient elimination, has been proved to be a critical molecular mechanism of IHD and accompanying myocardium dysfunction. Therefore, anti-oxidation therapy may be efficient. Chinese herbal medicine, including extractive compounds, decoctions, patent drugs, and injections, has shown its enormous potential in prevention and treatment of IHD as an effective antioxidant in experimental studies. The aim of this review is to highlight recent studies of Chinese herbal medicine in regulating oxidative stress in IHD. These studies represent recent progress of IHD treatment and indicate the possible pathways and target spots of Chinese herbal medicine.
authors.affiliation: The Second Clinical School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Dawei
authors.initials: D
authors.lastname: Wang
authors.affiliation: The Second Clinical School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Wang
authors.affiliation: The Second Clinical School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Yuntao
authors.initials: Y
authors.lastname: Liu
authors.affiliation: The Second Clinical School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China.
authors.forename: Zhen
authors.initials: Z
authors.lastname: Zhao
authors.affiliation: The Second Clinical School of Medicine, Guangzhou University of Chinese Medicine, Guangzhou 510405, China; Department of Immunology, School of Basic Medical Sciences, Fudan University, Shanghai, China. Electronic address: 851757626@qq.com.
authors.forename: Qing
authors.initials: Q
authors.lastname: Liu
mesh_terms: D000975:Antioxidants / Q000494:pharmacology; D004365:Drugs, Chinese Herbal / Q000494:pharmacology*; D006801:Humans; D008516:Medicine, Chinese Traditional / Q000379:methods / Q000639:trends; D017202:Myocardial Ischemia / Q000378:metabolism / Q000628:therapy; D018384:Oxidative Stress / Q000187:drug effects*; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D004365:Drugs, Chinese Herbal
keywords: Antioxidant; Chinese herbal medicine; Ischemic heart disease; Oxidative stress