title: Pneumothorax in cystic fibrosis: beyond the guidelines.
abstract: Pneumothorax is a serious but common complication in patients with cystic fibrosis (CF). It has adverse prognostic implications as well as associations with subsequent reduction in lung function and significant risk of recurrence. Management dilemmas frequently occur that are beyond current guidelines. We review the evidence and highlight management difficulties in pneumothoraces in CF.
authors.affiliation: Manchester Adult Cystic Fibrosis Centre, University Hospital of South Manchester, Southmoor Road, Wythenshawe, M23 9LT, United Kingdom; Institute of Inflammation and Repair, University of Manchester, United Kingdom.
authors.forename: Robert W
authors.initials: RW
authors.lastname: Lord
authors.affiliation: Manchester Adult Cystic Fibrosis Centre, University Hospital of South Manchester, Southmoor Road, Wythenshawe, M23 9LT, United Kingdom; Institute of Inflammation and Repair, University of Manchester, United Kingdom.
authors.forename: Andrew M
authors.initials: AM
authors.lastname: Jones
authors.affiliation: Manchester Adult Cystic Fibrosis Centre, University Hospital of South Manchester, Southmoor Road, Wythenshawe, M23 9LT, United Kingdom; Institute of Inflammation and Repair, University of Manchester, United Kingdom.
authors.forename: A Kevin
authors.initials: AK
authors.lastname: Webb
authors.affiliation: Manchester Adult Cystic Fibrosis Centre, University Hospital of South Manchester, Southmoor Road, Wythenshawe, M23 9LT, United Kingdom; Institute of Inflammation and Repair, University of Manchester, United Kingdom. Electronic address: peter.barry@uhsm.nhs.uk.
authors.forename: Peter J
authors.initials: PJ
authors.lastname: Barry
mesh_terms: D000293:Adolescent; D003550:Cystic Fibrosis / Q000150:complications* / Q000382:microbiology / Q000503:physiopathology; D003952:Diagnostic Imaging; D019468:Disease Management; D006801:Humans; D008297:Male; D011030:Pneumothorax / Q000000981:diagnostic imaging / Q000209:etiology* / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis; D012129:Respiratory Function Tests; D012307:Risk Factors
keywords: Cystic Fibrosis; Persistent air leak; Pleural intervention; Pleurodesis; Pneumothorax