title: National Cancer Centre Singapore Consensus Guidelines for Hepatocellular Carcinoma.
abstract: Hepatocellular carcinoma (HCC) is the 6th most common cancer in the world, but the second most common cause of cancer death. There is no universally accepted consensus practice guidelines for HCC owing to rapid developments in new treatment modalities, the heterogeneous epidemiology and clinical presentation of HCC worldwide. However, a number of regional and national guidelines currently exist which reflect practice relevant to the epidemiology and collective experience of the consensus group. In 2014, clinicians at the multidisciplinary Comprehensive Liver Cancer Clinic (CLCC) at the National Cancer Centre Singapore (NCCS) reviewed the latest published scientific data and existing international and regional practice guidelines, such as those of the National Comprehensive Cancer Network, American Association for the Study of Liver Diseases and the Asian Pacific Association for the Study of the Liver, and modified them to reflect local practice. These would serve as a template by which treatment outcomes can be collated and benchmarked against international data. The NCCS Consensus Guidelines for HCC have been successfully implemented in the CLCC since their publication online on 26(th) September 2014, and the guidelines allow outcomes of treatment to be compared to international data. These guidelines will be reviewed periodically to incorporate new data.
authors.affiliation: Division of Surgical Oncology, National Cancer Centre Singapore, Singapore; Department of Hepatopancreatobiliary/Transplantation Surgery, Singapore General Hospital, Singapore; Office of Clinical Sciences, Duke-NUS Graduate Medical School, Singapore, Singapore.
authors.forename: Pierce K H
authors.initials: PK
authors.lastname: Chow
authors.affiliation: Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
authors.forename: Su Pin
authors.initials: SP
authors.lastname: Choo
authors.affiliation: Department of Nuclear Medicine & PET, Singapore General Hospital, Singapore.
authors.forename: David C E
authors.initials: DC
authors.lastname: Ng
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: Richard H G
authors.initials: RH
authors.lastname: Lo
authors.affiliation: Department of Pathology, Singapore General Hospital, Singapore.
authors.forename: Michael L C
authors.initials: ML
authors.lastname: Wang
authors.affiliation: Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
authors.forename: Han Chong
authors.initials: HC
authors.lastname: Toh
authors.affiliation: Division of Medical Oncology, National Cancer Centre Singapore, Singapore.
authors.forename: David W M
authors.initials: DW
authors.lastname: Tai
authors.affiliation: Department of Hepatopancreatobiliary/Transplantation Surgery, Singapore General Hospital, Singapore.
authors.forename: Brian K P
authors.initials: BK
authors.lastname: Goh
authors.affiliation: Department of Hepatopancreatobiliary/Transplantation Surgery, Singapore General Hospital, Singapore.
authors.forename: Jen San
authors.initials: JS
authors.lastname: Wong
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: Kiang Hiong
authors.initials: KH
authors.lastname: Tay
authors.affiliation: Department of Nuclear Medicine & PET, Singapore General Hospital, Singapore.
authors.forename: Anthony S W
authors.initials: AS
authors.lastname: Goh
authors.affiliation: Department of Nuclear Medicine & PET, Singapore General Hospital, Singapore.
authors.forename: Sean X
authors.initials: SX
authors.lastname: Yan
authors.affiliation: Department of Nuclear Medicine & PET, Singapore General Hospital, Singapore.
authors.forename: Kelvin S H
authors.initials: KS
authors.lastname: Loke
authors.affiliation: Department of Nuclear Medicine & PET, Singapore General Hospital, Singapore.
authors.forename: Sue Ping
authors.initials: SP
authors.lastname: Thang
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: Apoorva
authors.initials: A
authors.lastname: Gogna
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: Chow Wei
authors.initials: CW
authors.lastname: Too
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: Farah Gillian
authors.initials: FG
authors.lastname: Irani
authors.affiliation: Department of Diagnostic Radiology, Singapore General Hospital, Singapore.
authors.forename: Sum
authors.initials: S
authors.lastname: Leong
authors.affiliation: Department of Pathology, Singapore General Hospital, Singapore.
authors.forename: Kiat Hon
authors.initials: KH
authors.lastname: Lim
authors.affiliation: Division of Oncologic Radiology, National Cancer Centre Singapore, Singapore.
authors.forename: Choon Hua
authors.initials: CH
authors.lastname: Thng
keywords: Diagnosis; Hepatocellular carcinoma; Practice guidelines; Radiation therapy; Surgery