title: Successfully treated but not fit for purpose: paying attention to chronic lung impairment after TB treatment.
abstract: In 2013, 86% of patients with newly diagnosed tuberculosis (TB) successfully completed treatment and were discharged from care. However, long-term studies in industrialised and resource-poor countries all point to a higher risk of death in TB survivors than in the general population. The likely explanation is chronic restrictive and obstructive lung disease consequent to TB. We call for better linkages between TB control programmes and respiratory medicine services, a better understanding of the burden of respiratory disability at the end of anti-tuberculosis treatment, and political, programmatic, clinical and research action to improve the quality of life of affected patients.
authors.affiliation: International Union Against Tuberculosis and Lung Disease, Paris, France; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK.
authors.forename: A D
authors.initials: AD
authors.lastname: Harries
authors.affiliation: International Union Against Tuberculosis and Lung Disease, Paris, France, National Tuberculosis Programme, Cotonou, Benin.
authors.forename: S
authors.initials: S
authors.lastname: Ade
authors.affiliation: National Heart and Lung Institute, Imperial College, London, UK.
authors.forename: P
authors.initials: P
authors.lastname: Burney
authors.affiliation: International Union Against Tuberculosis and Lung Disease, Paris, France; National Tuberculosis Control Programme, Hanoi, Viet Nam.
authors.forename: N B
authors.initials: NB
authors.lastname: Hoa
authors.affiliation: Division of Pulmonary, Allergy and Critical Care Medicine, Columbia University Medical Center, New York, Vital Strategies, New York, New York, USA.
authors.forename: N W
authors.initials: NW
authors.lastname: Schluger
authors.affiliation: International Union Against Tuberculosis and Lung Disease, Paris, France, Vital Strategies, New York, New York, USA.
authors.forename: J L
authors.initials: JL
authors.lastname: Castro
mesh_terms: D000328:Adult; D000995:Antitubercular Agents / Q000627:therapeutic use*; D019033:Delivery of Health Care, Integrated; D004185:Disability Evaluation; D006801:Humans; D008168:Lung / Q000187:drug effects* / Q000503:physiopathology; D008173:Lung Diseases, Obstructive / Q000175:diagnosis / Q000209:etiology* / Q000401:mortality / Q000503:physiopathology; D008297:Male; D011788:Quality of Life; D020127:Recovery of Function; D012129:Respiratory Function Tests; D012307:Risk Factors; D013997:Time Factors; D016896:Treatment Outcome; D014397:Tuberculosis, Pulmonary / Q000150:complications / Q000188:drug therapy* / Q000401:mortality / Q000503:physiopathology
chemical_list: D000995:Antitubercular Agents