title: Graphene-like 2D nanomaterial-based biointerfaces for biosensing applications.
abstract: Due to their unique structures and multifunctionalities, two-dimensional (2D) nanomaterials have aroused increasing interest in the construction of the novel biointerfaces for biosensing applications. Efforts in constructing novel biointerfaces led to exploit the more versatile and tunable graphene-like 2D nanomaterials (e.g. graphitic carbon nitride, boron nitride, transition metal dichalcogenides, and transition metal oxides) with various structural and compositional characteristics. This review highlights recent efforts in the design of graphene-like 2D nanomaterials and their derived biointerfaces and exploitation of their research on fluorescent sensors and a series of electrochemical sensors, including amperometric, electrochemiluminescence, photoelectrochemical and field-effect transistor sensors. Finally, we discuss some critical challenges and future perspectives in this field.
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology, Ministry of Education of the PR China and College of Chemistry, Central China Normal University, Wuhan 430079, China; School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164-2920, United States.
authors.forename: Chengzhou
authors.initials: C
authors.lastname: Zhu
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology, Ministry of Education of the PR China and College of Chemistry, Central China Normal University, Wuhan 430079, China; School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164-2920, United States. Electronic address: dan.du@mail.ccnu.edu.cn.
authors.forename: Dan
authors.initials: D
authors.lastname: Du
authors.affiliation: Key Laboratory of Pesticide and Chemical Biology, Ministry of Education of the PR China and College of Chemistry, Central China Normal University, Wuhan 430079, China; School of Mechanical and Materials Engineering, Washington State University, Pullman, Washington 99164-2920, United States. Electronic address: Yuehe.lin@wsu.edu.
authors.forename: Yuehe
authors.initials: Y
authors.lastname: Lin
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D004867:Equipment Design; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D008163:Luminescent Measurements / Q000295:instrumentation / Q000379:methods; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods; D013050:Spectrometry, Fluorescence / Q000295:instrumentation / Q000379:methods; D014173:Transistors, Electronic
chemical_list: D006108:Graphite
keywords: Biointerfaces; Electrochemical biosensors; Fluorescent biosensors; Graphene; Graphene-like 2D materials