title: Disseminated choroid plexus papillomas in adults: A case series and review of the literature.
abstract: Choroid plexus papillomas (CPPs) are uncommon, usually intraventricular, low-grade tumors, accounting for less than 1% of all intracranial neoplasms and 2-4% of brain tumors in children. Dissemination of CPPs to multiple levels of the neuraxis has been seldom observed. Thus far, only 26 adult patients have been reported in the English language literature. With some exceptions, disseminated CPPs have been observed in adults and involved multiple sites along the cerebrospinal fluid pathways. Occasionally, intraparenchymal extension has been documented, and secondary involvement of the suprasellar region has been reported in only five patients. Postoperative treatment of CPPs has not been standardized. Most recommended therapies have been extrapolated from a series of atypical papillomas or carcinomas of the choroid plexus in children. We herein report a series of three patients of disseminated choroid plexus papillomas providing additional insights into this relatively rare entity.
authors.affiliation: Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
authors.forename: Marwah M
authors.initials: MM
authors.lastname: Abdulkader
authors.affiliation: Department of Neurological Surgery, Indiana University School of Medicine, 340 W 10(th) Street #6200, Indianapolis, IN 46202, USA.
authors.forename: Nassir H
authors.initials: NH
authors.lastname: Mansour
authors.affiliation: Departments of Neurosurgery and Otolaryngology, Mayo Clinic, Rochester, MN 55905, USA.
authors.forename: Jamie J
authors.initials: JJ
authors.lastname: Van Gompel
authors.affiliation: Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
authors.forename: Gregory A
authors.initials: GA
authors.lastname: Bosh
authors.affiliation: Department of Neurology, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
authors.forename: Edward J
authors.initials: EJ
authors.lastname: Dropcho
authors.affiliation: Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN 46202, USA.
authors.forename: Jose M
authors.initials: JM
authors.lastname: Bonnin
authors.affiliation: Department of Neurological Surgery, Indiana University School of Medicine, 340 W 10(th) Street #6200, Indianapolis, IN 46202, USA. Electronic address: acohenmd@gmail.com.
authors.forename: Aaron A
authors.initials: AA
authors.lastname: Cohen-Gadol
mesh_terms: D000328:Adult; D002831:Choroid Plexus / Q000473:pathology; D016545:Choroid Plexus Neoplasms / Q000473:pathology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D020288:Papilloma, Choroid Plexus / Q000473:pathology*; D011184:Postoperative Period; D012107:Research Design
keywords: Adults; Choroid plexus papilloma; Disseminated