title: Relationship between functional capacity and health-related quality of life of patients with type-2 diabetes.
abstract: OBJECTIVE
  Physical function is a determinant of survival in chronic diseases, however, little is known about functional capacity (FC) and self-reported health status of patients with type-2 diabetes (T2D). This study investigated the relationship between FC and health related quality of life (HRQoL) of patients with T2D.
  
  
  METHODS
  This cross-sectional survey recruited 150 patients with T2D from a Nigerian university teaching hospital using purposive sampling technique. Socio-demographic and physical characteristics were assessed. FC and HRQoL including physical and mental health component summary (PCS and MCS) were assessed using the six minute walk test (6MWT) and Short-Form (SF-12) questionnaire respectively. Maximum oxygen consumption (VO2max) was estimated, pre and post 6MWT cardiovascular parameters and fasting blood glucose (FBG) were assessed. Data were analyzed using descriptive and inferential statistics. Alpha level was set at p<0.05.
  
  
  RESULTS
  There were 83(55.3%) women, means of age and FBG of participants were 64.2±8.7years and 7.4±2.4mmol/L respectively. The means of 6-min walk distance (6-MWD) and estimated VO2max were 341.55±41.82m and 9.2±0.7mL/kg/min respectively. Significant differences were found between pre and post HR (t=-44.71; p=0.001), SBP (t=-38.38; p=0.001) and DBP (t=-38.58; p=0.001) following 6MWT. The means of PCS and MCS of HRQoL were 48.67±5.51 and 58.39±2.86 respectively. There were significant correlations between FC and each of PCS (r=0.678; p=0.001) and MCS (r=0.211; p=0.009).
  
  
  CONCLUSIONS
  Patients with T2D demonstrated low functional capacity and reduced HRQoL. Significant relationship exists between FC and physical and mental component summary of HRQoL. Exercise intervention to improve FC and HRQoL were recommended.
authors.affiliation: Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria. Electronic address: tidebet@yahoo.com.
authors.forename: Taofeek O
authors.initials: TO
authors.lastname: Awotidebe
authors.affiliation: Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors.forename: Rufus A
authors.initials: RA
authors.lastname: Adedoyin
authors.affiliation: Department of Physiotherapy, College of Medical Sciences, University of Benin, Benin City, Edo State, Nigeria.
authors.forename: Kayode I
authors.initials: KI
authors.lastname: Oke
authors.affiliation: Department of Physiotherapy, University of Nigeria Teaching Hospital, Enugu, Enugu State, Nigeria.
authors.forename: Rita N
authors.initials: RN
authors.lastname: Ativie
authors.affiliation: Department of Nutrition, School of Public Health, University of Nairobi, Nairobi, Kenya.
authors.forename: Rose
authors.initials: R
authors.lastname: Opiyo
authors.affiliation: Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors.forename: Ebenezer O
authors.initials: EO
authors.lastname: Ikujeyisi
authors.affiliation: Department of Medicine, Endocrine and Metabolism Unit, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors.forename: Rosemary T
authors.initials: RT
authors.lastname: Ikem
authors.affiliation: Department of Medical Rehabilitation, College of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria.
authors.forename: Mubaraq A
authors.initials: MA
authors.lastname: Afolabi
mesh_terms: D000203:Activities of Daily Living; D000328:Adult; D016022:Case-Control Studies; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires
keywords: Functional capacity; Health related quality of life; Type-2 diabetes