title: Comparative evaluation of effect of complete denture wears on the flow rate of saliva in both medicated and apparently healthy patients.
abstract: OBJECTIVE
  In the denture wearing people, saliva is necessary to create adhesion, cohesion, and surface tension that ultimately leads to the increased retention of the denture. Medications have some influence on the flow rate of saliva and denture retention. The present study evaluates the effect of complete denture wear on the flow rate of saliva in both medicated and apparently healthy patients.
  
  
  METHODS
  The participants were 42 edentulous individuals aged 35-70 years requiring complete denture prostheses. The participants were divided into two groups of medicated and unmedicated. Unstimulated whole saliva was collected at 24 h and 3 months after the insertion of new complete dentures in both the groups. The data obtained were analyzed using Student's paired t-test and unpaired t-test. Intergroup changes were compared with unpaired t-test. Intragroup changes were compared with paired t-test using the Statistical Package for Social Sciences, version 22.0.
  
  
  RESULTS
  In the unmedicated group, the mean salivary flow rate was high at 24 h after denture insertion when compared to before denture insertion (P = 0.001 VHS). In the medicated group, the observation was highly significant (P = 0.007 HS) 24 h after denture insertion and after 3 months (P = 0.02 S) when compared to before denture insertion.
  
  
  CONCLUSIONS
  No significant difference in the salivary flow rate was found 3 months after denture insertion when compared to before denture insertion for both the medicated and unmedicated groups.
authors.affiliation: Department of Prosthodontics, Awadh Dental College and Hospital, Jamshedpur, Jharkhand, India.
authors.forename: Abhay
authors.initials: A
authors.lastname: Sonthalia
authors.affiliation: Department of Prosthodontics, Faculty of Dentistry, Melaka Manipal Medical College, Manipal University, Manipal, Karnataka, India.
authors.forename: Arun P
authors.initials: AP
authors.lastname: Chandrasekaran
authors.affiliation: Department of Oral Pathology, MA Rangoonwala Dental College, Maharashtra, India.
authors.forename: Sheetal P
authors.initials: SP
authors.lastname: Mhaske
authors.affiliation: Department of Prosthodontics, Darshan Dental College, Udaipur, Rajasthan, India.
authors.forename: Mayank
authors.initials: M
authors.lastname: Lau
authors.affiliation: Department of Oral Pathology and Microbiology, PSM College of Dental Science and Research, Thrissur, Kerala, India.
authors.forename: V R
authors.initials: VR
authors.lastname: Joshy
authors.affiliation: Department of Prosthodontics, PSM College of Dental Science and Research, Thrissur, Kerala, India.
authors.forename: George
authors.initials: G
authors.lastname: Attokaran
keywords: Complete denture flow; medication; saliva; unmedicated