title: Can we Improve Outcome in High Risk Surgery?
abstract: Despite the small number of high-risk surgical patients in comparison to all surgical patients, they account for the largest proportion of overall perioperative mortality. Goal directed hemodynamic support may result in a lower incidence of complications and reduced length of hospital stay in these patients. Beyond the standard monitoring of circulation, such as blood pressure and heart rate, further parameters and procedures such as pulse pressure/stroke volume variation-, stroke volume/cardiac index-, and central venous oxygen saturation-guided resuscitation may improve the outcome of high-risk surgical patients. The aim of this review is to focus on the results of animal and clinical studies investigating the usefulness of these indices in the context of goal-directed perioperative support.
authors.affiliation: University of Szeged, Faculty of Medicine, Department of Anaesthesiology and Intensive Therapy, Szeged, Hungary.
authors.forename: Andras
authors.initials: A
authors.lastname: Mikor
authors.affiliation: University of Szeged, Faculty of Medicine, Department of Anaesthesiology and Intensive Therapy, Szeged, Hungary.
authors.forename: Zsolt
authors.initials: Z
authors.lastname: Molnar
keywords: High-risk surgery; central venous oxygen saturation; goal directed therapy; improved outcome; pulse pressure variation; stroke volume