title: A novel anticancer theranostic pro-prodrug based on hypoxia and photo sequential control.
abstract: A novel anticancer pro-prodrug (GMC-CAE-NO2) with diagnosis and therapy functions based on hypoxia and photo sequential control was designed. It provides a platform for constructing theranostic pro-prodrugs to release active drugs controlled by hypoxic status and UV illumination.
authors.affiliation: Key Laboratory of Chemical Biology of Hebei Province, College of Chemistry and Environmental Science, Hebei University, Baoding 071002, China.
authors.forename: Weipei
authors.initials: W
authors.lastname: Feng
authors.forename: Chunyue
authors.initials: C
authors.lastname: Gao
authors.forename: Wei
authors.initials: W
authors.lastname: Liu
authors.forename: Huihui
authors.initials: H
authors.lastname: Ren
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.forename: Kun
authors.initials: K
authors.lastname: Ge
authors.forename: Shenghui
authors.initials: S
authors.lastname: Li
authors.forename: Guoqiang
authors.initials: G
authors.lastname: Zhou
authors.forename: Hongyan
authors.initials: H
authors.lastname: Li
authors.forename: Shuxiang
authors.initials: S
authors.lastname: Wang
authors.forename: Guang
authors.initials: G
authors.lastname: Jia
authors.forename: Zhenhua
authors.initials: Z
authors.lastname: Li
authors.forename: Jinchao
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000970:Antineoplastic Agents / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D002470:Cell Survival / Q000187:drug effects; D006801:Humans; D000860:Hypoxia / Q000175:diagnosis* / Q000188:drug therapy*; D061986:MCF-7 Cells; D055668:Photochemical Processes; D011355:Prodrugs / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use*; D000068936:Theranostic Nanomedicine
chemical_list: D000970:Antineoplastic Agents; D011355:Prodrugs