title: Facile Syntheses of AM-toxins and Analogs as Cyclic Depsipeptides by the Solid-phase Method.
abstract: The cyclic depsipeptides, AM-toxins I and II and AM-toxin I analogs, were efficiently and rapidly prepared by the Fmoc-based solid-phase method for the synthesis of linear depsipeptides, with N-[(dimethylamino)-1H-1,2,3-triazolo[4,5-b]pyridin-1-ylmethylene]-N-methylmethanaminium hexafluorophosphate N-oxide (HATU) being used for their subsequent cyclization.
authors.affiliation: a Graduate School of Agriculture, Kyoto University.
authors.forename: M
authors.initials: M
authors.lastname: Miyashita
authors.affiliation: a Graduate School of Agriculture, Kyoto University.
authors.forename: T
authors.initials: T
authors.lastname: Nakamori
authors.affiliation: a Graduate School of Agriculture, Kyoto University.
authors.forename: T
authors.initials: T
authors.lastname: Murai
authors.affiliation: a Graduate School of Agriculture, Kyoto University.
authors.forename: H
authors.initials: H
authors.lastname: Miyagawa
authors.affiliation: a Graduate School of Agriculture, Kyoto University.
authors.forename: M
authors.initials: M
authors.lastname: Akamatsu
authors.affiliation: a Graduate School of Agriculture, Kyoto University.
authors.forename: T
authors.initials: T
authors.lastname: Ueno
keywords: AM-toxin; HATU; cyclic depsipeptide; host-specific toxin; solid-phase synthesis