title: Disseminated Mycobacterium abscessus Complex Infection Manifesting as Multiple Areas of Lymphadenitis and Skin Abscess in the Preclinical Stage of Acute Lymphocytic Leukemia.
abstract: A 37-year-old woman was admitted to a hospital due to a prolonged fever and a rash on her legs. She had systemic lymphadenitis and a skin abscess on her left leg. Pathological findings of a left leg skin biopsy revealed abscess formation with granulomatous dermatitis, Mycobacterium abscessus complex was cultured from the resected left supraclavicular lymph node, and disseminated M. abscessus complex infection was diagnosed. She was treated with combination treatment with antimicrobials and percutaneous drainage, and her clinical findings improved. Four months later, she developed acute lymphocytic leukemia. Leukemia is a risk factor for disseminated M. abscessus complex infection, even before developing leukemia.
authors.affiliation: Department of Respiratory Medicine, University of Occupational and Environmental Health, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tahara
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Yatera
authors.forename: Kei
authors.initials: K
authors.lastname: Yamasaki
authors.forename: Takeshi
authors.initials: T
authors.lastname: Orihashi
authors.forename: Makoto
authors.initials: M
authors.lastname: Hirosawa
authors.forename: Takaaki
authors.initials: T
authors.lastname: Ogoshi
authors.forename: Shingo
authors.initials: S
authors.lastname: Noguchi
authors.forename: Chinatsu
authors.initials: C
authors.lastname: Nishida
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Ishimoto
authors.forename: Akihito
authors.initials: A
authors.lastname: Yonezawa
authors.forename: Junichi
authors.initials: J
authors.lastname: Tsukada
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Mukae
mesh_terms: D000038:Abscess / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D005260:Female; D006801:Humans; D008199:Lymphadenitis / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D009165:Mycobacterium Infections, Nontuberculous / Q000150:complications* / Q000188:drug therapy / Q000382:microbiology; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000209:etiology*; D012871:Skin Diseases / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents