title: Bladder Preservation for Muscle Invasive Bladder Cancer.
abstract: The standard treatment for muscle invasive bladder cancer (MIBC) has been considered to be radical cystectomy (RC) with pelvic lymphadenectomy. However morbidity and impact on quality of life is significant. Radiotherapy has been used in MIBC patients who choose bladder preservation or who are unfit for RC with comparable outcomes. Evidence from some prospective and large retrospective series supports the use of radiotherapy as an attractive alternative option. In this paper we review the evidence and practice of bladder preservation strategies with radiotherapy for muscle invasive bladder cancer.
authors.affiliation: The Christie NHS Foundation Trust , Manchester, UK.
authors.forename: Arafat
authors.initials: A
authors.lastname: Mirza
authors.affiliation: The Christie NHS Foundation Trust, Manchester, UK; The Institute of Cancer Sciences, University of Manchester, Manchester Academic Health Sciences Centre, Manchester, UK.
authors.forename: Ananya
authors.initials: A
authors.lastname: Choudhury
keywords: Bladder cancer; chemoradiotherapy; organ preservation; radical cystectomy