title: [Not Available].
authors.affiliation: Afssaps, Saint Denis, France.
authors.forename: Pierre-Henri
authors.initials: PH
authors.lastname: Bertoye
authors.affiliation: Bristol Myers Squibb, Rueil Malmaison, France. Electronic address: soizic.courcier@bms.com.
authors.forename: Soizic
authors.initials: S
authors.lastname: Courcier-Duplantier
authors.affiliation: DRRC, Hôpital Saint Louis, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Best
keywords: BPC; adaptation; circuit du médicament; enjeux; essais cliniques; mise en œuvre; monitoring; pharmacovigilance; risques