title: Iodine(III)-Mediated Selective Intermolecular C-H Amination for the Chemical Diversification of Tryptamines.
abstract: Defined hypervalent iodine reagents of the general structure PhI[N(SO2R)(SO2R')]2 promote the selective direct C-H-amination of the indole core of various tryptamines. Starting from a general C2-amination strategy, subsequent transformations enable a variety of site-selective functionalizations, which proceed with noteworthy high chemoselectivity and provide an overall access to structurally diversified products.
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Avenida Països Catalans 16, E-43007 Tarragona, Spain.
authors.forename: Alexandra E
authors.initials: AE
authors.lastname: Bosnidou
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Avenida Països Catalans 16, E-43007 Tarragona, Spain.
authors.forename: Alba
authors.initials: A
authors.lastname: Millán
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Avenida Països Catalans 16, E-43007 Tarragona, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Ceballos
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Avenida Països Catalans 16, E-43007 Tarragona, Spain.
authors.forename: Claudio
authors.initials: C
authors.lastname: Martínez
authors.affiliation: Institute of Chemical Research of Catalonia (ICIQ), The Barcelona Institute of Science and Technology , Avenida Països Catalans 16, E-43007 Tarragona, Spain.|ICREA , Passeig Lluís Companys 23, 08010 Barcelona, Spain.
authors.forename: Kilian
authors.initials: K
authors.lastname: Muñiz