title: Cell behaviors and dynamics during angiogenesis.
abstract: Vascular networks are formed and maintained through a multitude of angiogenic processes, such as sprouting, anastomosis and pruning. Only recently has it become possible to study the behavior of the endothelial cells that contribute to these networks at a single-cell level in vivo This Review summarizes what is known about endothelial cell behavior during developmental angiogenesis, focusing on the morphogenetic changes that these cells undergo.
authors.affiliation: Biozentrum der Universität Basel, Klingelbergstrasse 50/70, Basel CH-4056, Switzerland.
authors.forename: Charles
authors.identifier: 0000-0002-9837-6916
authors.initials: C
authors.lastname: Betz
authors.affiliation: Biozentrum der Universität Basel, Klingelbergstrasse 50/70, Basel CH-4056, Switzerland.
authors.forename: Anna
authors.initials: A
authors.lastname: Lenard
authors.affiliation: Biozentrum der Universität Basel, Klingelbergstrasse 50/70, Basel CH-4056, Switzerland.
authors.forename: Heinz-Georg
authors.initials: HG
authors.lastname: Belting
authors.affiliation: Biozentrum der Universität Basel, Klingelbergstrasse 50/70, Basel CH-4056, Switzerland Markus.Affolter@unibas.ch.
authors.forename: Markus
authors.identifier: 0000-0002-5171-0016
authors.initials: M
authors.lastname: Affolter
mesh_terms: D000818:Animals; D002459:Cell Fusion; D042783:Endothelial Cells / Q000166:cytology* / Q000378:metabolism; D006801:Humans; D008954:Models, Biological; D009024:Morphogenesis; D018919:Neovascularization, Physiologic; D015398:Signal Transduction
keywords: Anastomosis; Angiogenesis; Endothelial cells; Live imaging; Pruning; Sprouting; Vegf; Zebrafish