title: A new hydroxynaphthyl benzothiazole derived fluorescent probe for highly selective and sensitive Cu(2+) detection.
abstract: A new reactive probe, 1-(benzo[d]thiazol-2-yl)naphthalen-2-yl-picolinate (BTNP), was designed and synthesized. BTNP acts as a highly selective probe to Cu(2+) in DMSO/H2O (7/3, v/v, Tris-HCl 10mM, pH=7.4) solution based on Cu(2+) catalyzed hydrolysis of the picolinate ester moiety in BTNP, which leads to the formation of an ESIPT active product with dual wavelength emission enhancement. The probe also possesses the advantages of simple synthesis, rapid response and high sensitivity. The pseudo-first-order reaction rate constant was calculated to be 0.205min(-1). Moreover, application of BTNP to Cu(2+) detection in living cells and real water samples was also explored.
authors.affiliation: Department of Chemistry, Bohai University, Jinzhou 121013, China. Electronic address: ljtang@bhu.edu.cn.
authors.forename: Lijun
authors.initials: L
authors.lastname: Tang
authors.affiliation: Department of Chemistry, Bohai University, Jinzhou 121013, China.
authors.forename: Ping
authors.initials: P
authors.lastname: He
authors.affiliation: Department of Chemistry, Bohai University, Jinzhou 121013, China.
authors.forename: Keli
authors.initials: K
authors.lastname: Zhong
authors.affiliation: Department of Chemistry, Bohai University, Jinzhou 121013, China.
authors.forename: Shuhua
authors.initials: S
authors.lastname: Hou
authors.affiliation: Department of Chemistry, Bohai University, Jinzhou 121013, China.
authors.forename: Yanjiang
authors.initials: Y
authors.lastname: Bian
mesh_terms: D052160:Benzothiazoles / Q000737:chemistry*; D002413:Cations, Divalent / Q000032:analysis; D003300:Copper / Q000032:analysis*; D005456:Fluorescent Dyes / Q000737:chemistry*; D006801:Humans; D057230:Limit of Detection; D061986:MCF-7 Cells; D008856:Microscopy, Fluorescence / Q000379:methods; D061848:Optical Imaging / Q000379:methods; D013050:Spectrometry, Fluorescence / Q000379:methods; D014867:Water / Q000032:analysis
chemical_list: D052160:Benzothiazoles; D002413:Cations, Divalent; D005456:Fluorescent Dyes; D014867:Water; D003300:Copper; C005465:benzothiazole
keywords: Benzothiazole; Cell imaging; Cu(2+) catalyzed hydrolysis; Cu(2+) recognition; ESIPT