title: Cartilage defect repair in horses: Current strategies and recent developments in regenerative medicine of the equine joint with emphasis on the surgical approach.
abstract: Chondral and osteochondral lesions due to injury or other pathology are highly prevalent conditions in horses (and humans) and commonly result in the development of osteoarthritis and progression of joint deterioration. Regenerative medicine of articular cartilage is an emerging clinical treatment option for patients with articular cartilage injury or disease. Functional articular cartilage restoration, however, remains a major challenge, but the field is progressing rapidly and there is an increasing body of supportive clinical and scientific evidence. This review gives an overview of the established and emerging surgical techniques employed for cartilage repair in horses. Through a growing insight in surgical cartilage repair possibilities, surgeons might be more stimulated to explore novel techniques in a clinical setting.
authors.affiliation: Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 112, 3584 CM Utrecht, NL, Netherlands. Electronic address: S.M.Cokelaere@uu.nl.
authors.forename: Stefan
authors.initials: S
authors.lastname: Cokelaere
authors.affiliation: Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 112, 3584 CM Utrecht, NL, Netherlands; Department of Orthopaedics, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, NL, Netherlands.
authors.forename: Jos
authors.initials: J
authors.lastname: Malda
authors.affiliation: Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 112, 3584 CM Utrecht, NL, Netherlands.
authors.forename: René
authors.initials: R
authors.lastname: van Weeren
mesh_terms: D000818:Animals; D002357:Cartilage Diseases / Q000601:surgery / Q000662:veterinary*; D002358:Cartilage, Articular / Q000473:pathology / Q000601:surgery*; D006734:Horse Diseases / Q000601:surgery*; D006736:Horses; D007592:Joint Diseases / Q000601:surgery / Q000662:veterinary*; D007596:Joints / Q000601:surgery*; D044968:Regenerative Medicine / Q000379:methods*
keywords: Cartilage defect repair; Horse; Osteoarthritis; Osteochondral lesions; Surgical techniques