title: Mitochondrial Networking in T Cell Memory.
abstract: T-lymphocytes show large changes in ATP demand and nutrient utilization, imposed by their different roles as T memory and T effector cells. Therefore, T cell remodeling represents a bioenergetic challenge to mitochondria. New work from Buck et al. links changes in mitochondrial shape to T cell fate choice.
authors.affiliation: Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address: mliesa@mednet.ucla.edu.
authors.forename: Marc
authors.initials: M
authors.lastname: Liesa
authors.affiliation: Division of Endocrinology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA. Electronic address: oshirihai@mednet.ucla.edu.
authors.forename: Orian S
authors.initials: OS
authors.lastname: Shirihai
mesh_terms: D018414:CD8-Positive T-Lymphocytes; D004734:Energy Metabolism; D006801:Humans; D007156:Immunologic Memory; D008928:Mitochondria / Q000378:metabolism*; D013601:T-Lymphocytes