title: Evidence of Local HIV Transmission in the African Community of King County, Washington.
abstract: Little is known about the frequency of ongoing HIV transmission within U.S. African immigrant communities. We used HIV surveillance and partner services data to describe African-born persons newly reported with HIV infection in King County (KC), WA from 1/1/2010 to 12/31/2013. We performed phylogenetic clustering analysis of HIV-1 pol to identify putative transmission events within this population. From 2010 to 2013, 1148 KC adults were reported with HIV, including 102 (9 %) born in Africa. Forty-one African-born cases were interviewed and reported diagnosis after arrival in the U.S. Fourteen (34 %) reported ≥1 negative test prior to diagnosis, and 9 (26 %) reported ≥1 negative test after U.S. arrival. Pol genotypes were available for seven of these nine. For two of these seven, a KC case was the nearest phylogenetic neighbor; two others were infected with subtype B virus. We found substantial evidence of ongoing HIV transmission in the African community of KC.
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA. rkerani@uw.edu.|Department of Medicine, University of Washington, Seattle, WA, USA. rkerani@uw.edu.|Department of Epidemiology, University of Washington, Seattle, WA, USA. rkerani@uw.edu.
authors.forename: Roxanne P
authors.identifier: 0000-0002-4416-4280
authors.initials: RP
authors.lastname: Kerani
authors.affiliation: Department of Global Health, University of Washington, Seattle, WA, USA.
authors.forename: Joshua T
authors.initials: JT
authors.lastname: Herbeck
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA.|Department of Epidemiology, University of Washington, Seattle, WA, USA.
authors.forename: Susan E
authors.initials: SE
authors.lastname: Buskin
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA.|Department of Medicine, University of Washington, Seattle, WA, USA.
authors.forename: Julia C
authors.initials: JC
authors.lastname: Dombrowksi
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Bennett
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Barash
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA.|Department of Medicine, University of Washington, Seattle, WA, USA.
authors.forename: Lindley A
authors.initials: LA
authors.lastname: Barbee
authors.affiliation: HIV/STD Program, Public Health - Seattle and King County, Seattle, WA, USA.|Department of Medicine, University of Washington, Seattle, WA, USA.|Department of Epidemiology, University of Washington, Seattle, WA, USA.
authors.forename: Matthew R
authors.initials: MR
authors.lastname: Golden
mesh_terms: D000328:Adult; D001741:Black or African American / Q000706:statistics & numerical data*; D054242:Emigrants and Immigrants / Q000706:statistics & numerical data*; D005260:Female; D015658:HIV Infections / Q000145:classification* / Q000175:diagnosis / Q000208:ethnology* / Q000635:transmission; D006801:Humans; D008297:Male; D008875:Middle Aged; D014861:Washington / Q000453:epidemiology
keywords: African; HIV; Immigrants; Migrants; Subtypes