title: A dinosaurian facial deformity and the first occurrence of ameloblastoma in the fossil record.
abstract: Despite documentation of various types of neoplastic pathologies encountered in the vertebrate fossil record, no ameloblastic tumours have been recognised so far. Ameloblastoma is a benign neoplasic tumour with a strong preponderance for the mandible. Here, we report for the first time the presence of an ameloblastoma neoplasm in the lower jaw of a specimen referred to the derived non-hadrosaurid hadrosauroid dinosaur Telmatosaurus transsylvanicus from the uppermost Cretaceous of the Haeg Basin in Romania. The location, external appearance and internal structure of the pathological outgrowth provide clear evidence for the diagnosis of ameloblastoma in Telmatosaurus. This report extends the range of pathologies encountered in hadrosauroid dinosaurs. In addition, recognition of an ameloblastoma neoplasm in a taxon lying close to the origin of 'duck-billed' hadrosaurid dinosaurs confirms the predisposition of this clade towards neoplasia pathologies already in its basal members.
authors.affiliation: Laboratory of Paleotheriology and Quaternary Geology, Faculty of Biology and Geology, BabeS-Bolyai University, 1, M. Kogălniceanu Str., 400084 Cluj-Napoca, Romania.
authors.forename: Mihai D
authors.initials: MD
authors.lastname: Dumbravă
authors.affiliation: Department of Medicine, Northeast Ohio Medical University, Rootstown, 44505 Ohio, USA.
authors.forename: Bruce M
authors.initials: BM
authors.lastname: Rothschild
authors.affiliation: Center for Functional Anatomy and Evolution, Johns Hopkins School of Medicine, 1830 E. Monument St., Room 306 Baltimore, MD 21205, USA.
authors.forename: David B
authors.initials: DB
authors.lastname: Weishampel
authors.affiliation: Faculty of Geology and Geophysics, University of Bucharest, 1, N. Bălcescu Blvd., 010041 Bucharest, Romania.
authors.forename: Zoltán
authors.initials: Z
authors.lastname: Csiki-Sava
authors.affiliation: Faculty of Geology and Geophysics, University of Bucharest, 1, N. Bălcescu Blvd., 010041 Bucharest, Romania.
authors.forename: Răzvan A
authors.initials: RA
authors.lastname: Andrei
authors.affiliation: Ocean and Earth Science, National Oceanography Centre, University of Southampton, Waterfront Campus, European Way, Southampton, SO14 3ZH, UK.
authors.forename: Katharine A
authors.initials: KA
authors.lastname: Acheson
authors.affiliation: Laboratory of Paleotheriology and Quaternary Geology, Faculty of Biology and Geology, BabeS-Bolyai University, 1, M. Kogălniceanu Str., 400084 Cluj-Napoca, Romania.
authors.forename: Vlad A
authors.initials: VA
authors.lastname: Codrea
mesh_terms: D000564:Ameloblastoma / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D000818:Animals; D025061:Dinosaurs; D005580:Fossils; D008334:Mandible / Q000473:pathology*; D008339:Mandibular Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000662:veterinary*; D012383:Romania