title: [Acute Kidney Injury, Type - 3 cardiorenal syndrome, Biomarkers, Renal Replacement Therapy].
abstract: Cardiovascular disease and major cardiovascular events represent main cause of death in both acute and chronic kidney disease patients. Kidney and heart failure are common and frequently co-exist This organ-organ interaction, also called organ cross-talk, leads to well-known definition of cardiorenal syndrome (CRS). Here we will describe cardiovascular involvement in patients with acute kidney injury (AKI). Also known as Type-3 CRS or acute reno-cardiac CRS, it occurs when AKI contributes and/or precipitates development of acute cardiac injury. AKI may directly or indirectly produces an acute cardiac event and it can be associated with volume overload, metabolic acidosis and electrolytes disorders such as hyperkalemia and hypocalcemia, coronary artery disease, left ventricular dysfunction and fibrosis which has been also described in patients with AKI with the consequence of direct negative effects on cardiac performance.
authors.forename: Luca
authors.initials: L
authors.lastname: Di Lullo
authors.forename: Antonio
authors.initials: A
authors.lastname: Bellasi
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Barbera
authors.forename: Mario
authors.initials: M
authors.lastname: Cozzolino
authors.forename: Domenico
authors.initials: D
authors.lastname: Russo
authors.forename: Antonio
authors.initials: A
authors.lastname: De Pascalis
authors.forename: Francesca
authors.initials: F
authors.lastname: Santoboni
authors.forename: Annalisa
authors.initials: A
authors.lastname: Villani
authors.forename: Silvia
authors.initials: S
authors.lastname: De Rosa
authors.forename: Marco
authors.initials: M
authors.lastname: Colafelice
authors.forename: Luigi
authors.initials: L
authors.lastname: Russo
authors.forename: Claudio
authors.initials: C
authors.lastname: Ronco
mesh_terms: D058186:Acute Kidney Injury / Q000628:therapy*; D015415:Biomarkers / Q000032:analysis; D059347:Cardio-Renal Syndrome / Q000145:classification* / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D017582:Renal Replacement Therapy; D012720:Severity of Illness Index
chemical_list: D015415:Biomarkers