title: Gold-Catalyzed Povarov-Type Reaction of Fluorinated Imino Esters and Furans.
abstract: A gold-catalyzed Povarov-type reaction of fluorinated imino esters and furans is described. The process, which takes place in dichoromethane at room temperature, gives rise to novel fluorinated tetrahydrofuran-fused tetrahydroquinolines in good yields and moderate levels of diastereoselectivity in a very simple manner. The reported examples expand the versatility of the Povarov reaction to unprecedented fluorinated substrates, generating scaffolds that contain quaternary α-amino acid units.
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia , 46100 Burjassot, Spain.
authors.forename: Álvaro
authors.initials: Á
authors.lastname: Sanz-Vidal
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia , 46100 Burjassot, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Miró
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia , 46100 Burjassot, Spain.
authors.forename: María
authors.initials: M
authors.lastname: Sánchez-Roselló
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia , 46100 Burjassot, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Del Pozo
authors.affiliation: Departamento de Química Orgánica, Universidad de Valencia , 46100 Burjassot, Spain.|Laboratorio de Moléculas Orgánicas, Centro de Investigación Príncipe Felipe , 46012 Valencia, Spain.
authors.forename: Santos
authors.initials: S
authors.lastname: Fustero