title: Changes in Behavior and Blood Corticosterone Level in Male and Female Rats after Single Administration of Obestatin Fragment 1-4.
abstract: Single administration of the obestatin fragment 1-4 (300 nmol/kg) to male Wistar rats produced a significant weight loss in male rats on observation days 5-8, while in female rats only on day 8. In addition, males demonstrated decreased risk factor in the elevated plus-maze test, but no effect of the preparation on behavior of female rats was revealed. Obestatin fragment 1-4 had no effect on corticosterone level 1 week after single administration in both females and male rats.
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia. motorykina.katerina@gmail.com.
authors.forename: E S
authors.initials: ES
authors.lastname: Motorykina
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: E A
authors.initials: EA
authors.lastname: Khirazova
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: M V
authors.initials: MV
authors.lastname: Maslova
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: A V
authors.initials: AV
authors.lastname: Graf
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: A S
authors.initials: AS
authors.lastname: Maklakova
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Bayzhumanov
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: O D
authors.initials: OD
authors.lastname: Kurko
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: L A
authors.initials: LA
authors.lastname: Andreeva
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: N A
authors.initials: NA
authors.lastname: Sokolova
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: N F
authors.initials: NF
authors.lastname: Myasoedov
authors.affiliation: Department of Human and Animal Physiology, M. V. Lomonosov Moscow State University, Moscow, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Kamenskii
mesh_terms: D000818:Animals; D019440:Anti-Obesity Agents / Q000494:pharmacology*; D003345:Corticosterone / Q000097:blood; D005260:Female; D008297:Male; D018782:Maze Learning; D009842:Oligopeptides / Q000494:pharmacology*; D017208:Rats, Wistar; D012309:Risk-Taking; D013315:Stress, Psychological / Q000097:blood
chemical_list: D019440:Anti-Obesity Agents; D009842:Oligopeptides; C000613891:phenylalanyl-asparginyl-alanyl-prolinamide; D003345:Corticosterone
keywords: animal behavior; corticosterone; obestatin; regulatory peptides; stress