title: Detection of Zika virus RNA in whole blood of imported Zika virus disease cases up to 2 months after symptom onset, Israel, December 2015 to April 2016.
abstract: Zika virus RNA presence in serum, whole-blood and urine samples from six Israeli travellers symptomatic for Zika virus disease was examined. Whole-blood samples were positive for as late as 2 months (58 days) post-symptom onset, longer than for urine (26 days) and serum (3 days). These findings suggest the utility of whole blood in Zika infection diagnosis.
authors.affiliation: Central Virology Laboratory, Ministry of Health, Tel-Hashomer, Israel.
authors.forename: Yaniv
authors.initials: Y
authors.lastname: Lustig
authors.forename: Ella
authors.initials: E
authors.lastname: Mendelson
authors.forename: Nir
authors.initials: N
authors.lastname: Paran
authors.forename: Sharon
authors.initials: S
authors.lastname: Melamed
authors.forename: Eli
authors.initials: E
authors.lastname: Schwartz
mesh_terms: D000293:Adolescent; D000328:Adult; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007557:Israel / Q000453:epidemiology; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood* / Q000652:urine*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D063189:Symptom Assessment; D014195:Travel; D055815:Young Adult; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000175:diagnosis* / Q000453:epidemiology / Q000821:virology*
chemical_list: D012367:RNA, Viral
keywords: Israel; Zika RNA; serum; urine; whole blood