title: Colonization and effector functions of innate lymphoid cells in mucosal tissues.
abstract: Innate lymphoid cells (ILCs) protect mucosal barrier tissues to fight infection and maintain tissue integrity. ILCs and their progenitors are developmentally programmed to migrate, differentiate and populate various mucosal tissues and associated lymphoid tissues. Functionally mature ILC subsets respond to diverse pathogens such as bacteria, viruses, fungi and parasites in subset-specific manners. In this review, we will discuss how ILCs populate mucosal tissues and regulate immune responses to distinct pathogens to protect the host and maintain tissue integrity.
authors.affiliation: Laboratory of Immunology and Hematopoiesis, Department of Comparative Pathobiology, Weldon School of Biomedical Engineering, Purdue Institute of Inflammation, Immunology and Infectious Diseases, Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: Myunghoo
authors.initials: M
authors.lastname: Kim
authors.affiliation: Laboratory of Immunology and Hematopoiesis, Department of Comparative Pathobiology, Weldon School of Biomedical Engineering, Purdue Institute of Inflammation, Immunology and Infectious Diseases, Purdue Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA. Electronic address: chkim@purdue.edu.
authors.forename: Chang H
authors.initials: CH
authors.lastname: Kim
mesh_terms: D000818:Animals; D001419:Bacteria / Q000276:immunology; D005658:Fungi / Q000276:immunology; D006801:Humans; D007113:Immunity, Innate; D018928:Immunity, Mucosal; D008214:Lymphocytes / Q000276:immunology*; D009092:Mucous Membrane / Q000276:immunology*; D010271:Parasites / Q000276:immunology; D014780:Viruses / Q000276:immunology
keywords: Infection; Innate lymphoid cells; Intestine; Migration; Mucosal tissues