title: Effect of Capsaicin Cream on the Secretion of the Submandibular and Parotid Gland in the General Population with Different Chilli-eating Habits.
abstract: OBJECTIVE
  To investigate the effect of capsaicin cream on the secretion of the submandibular gland (SMG) and the parotid gland (PG) in the general population, with different chilli-eating habits.
  
  
  METHODS
  In two groups with different chilli-eating habits, the salivary flow rate of the SMG and the PG was detected at statics and different times, after application of capsaicin cream.
  
  
  RESULTS
  In both groups, the topical application of capsaicin cream could significantly increase the salivary secretion of SMG (P < 0.05), but the increase in the salivary flow rate of the SMG between the two groups had no significant difference (P > 0.05). On the other hand, although the salivary flow rate of PG also increased after stimulation, the increase had no statistical difference (P > 0.05).
  
  
  CONCLUSIONS
  The application of capsaicin cream can effectively promote the secretion of the SMG and the PG, and its effect is independent of chilli-eating habits, which indicates that topical application of capsaicin cream can be considered as a potential treatment for the hypofunction of the salivary gland.
authors.forename: Yang
authors.initials: Y
authors.lastname: Wang
authors.forename: Zhen
authors.initials: Z
authors.lastname: Wang
authors.forename: Guang Yan
authors.initials: GY
authors.lastname: Yu
authors.forename: Zhan Gui
authors.initials: ZG
authors.lastname: Tang
authors.forename: Ji An
authors.initials: JA
authors.lastname: Hu
mesh_terms: D000328:Adult; D002211:Capsaicin / Q000494:pharmacology*; D004655:Emulsions; D005247:Feeding Behavior; D005260:Female; D006801:Humans; D008297:Male; D010306:Parotid Gland / Q000187:drug effects* / Q000378:metabolism; D012463:Saliva / Q000378:metabolism; D018689:Sensory System Agents / Q000494:pharmacology*; D013363:Submandibular Gland / Q000187:drug effects* / Q000378:metabolism; D055815:Young Adult
chemical_list: D004655:Emulsions; D018689:Sensory System Agents; D002211:Capsaicin