title: Cardiac Autonomic Drive during Arterial Hypertension and Metabolic Disturbances.
abstract: ANS support of the cardiac work was assessed with analysis of heart rate variability in representative samples of patients with arterial hypertension and metabolic disturbances manifested by overweight, classes I-II obesity, compromised glucose tolerance, and type II diabetes. Initially enhanced sympathetic effects on the heart rate demonstrated no further increase during the orthostatic test in contrast to suprasegmentary influences enhanced by this test. The pronouncedness of revealed peculiarities in ANS drive to the heart correlated with metabolic disturbances, and these peculiarities attained maximum in patients with type II diabetes.
authors.affiliation: E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia. viksbest@mail.ru.
authors.forename: S I
authors.initials: SI
authors.lastname: Kseneva
authors.affiliation: E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia.
authors.forename: E V
authors.initials: EV
authors.lastname: Borodulina
authors.affiliation: E.D. Goldberg Research Institute of Pharmacology and Regenerative Medicine, Tomsk, Russia.
authors.forename: O Yu
authors.initials: OY
authors.lastname: Trifonova
authors.affiliation: National Research Tomsk State University, Tomsk, Russia.
authors.forename: V V
authors.initials: VV
authors.lastname: Udut
mesh_terms: D001341:Autonomic Nervous System / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000503:physiopathology*; D005260:Female; D006339:Heart Rate; D006801:Humans; D006973:Hypertension / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D009200:Myocardial Contraction; D009765:Obesity / Q000503:physiopathology*
keywords: arterial hypertension; heart rate variability; metabolic disturbances