title: [HER2 testing in gastric cancer : Results of a meeting of German experts].
abstract: Valid HER2 testing is essential for the optimal care of patients with HER2-positive gastric cancer and the correct use of first-line treatment. Although all cases of breast cancer are routinely tested for the HER2 status, HER2 testing in gastric cancer has still not become part of the routine and is usually only done upon request by the therapist. An interdisciplinary group of German experts has taken on the challenges of HER2 testing in gastric cancer as an opportunity to address essential aspects and questions on the practical use of HER2 testing in this indication from the perspective of pathologists and therapists. The recommendations made in this article reflect the consensus of all participants and correspond to their opinions and long-term experience.
authors.affiliation: Institut für Pathologie, Universitätsklinikum Carl Gustav Carus, TU Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland. Gustavo.Baretton@uniklinikum-dresden.de.
authors.forename: G
authors.initials: G
authors.lastname: Baretton
authors.affiliation: Institut für Pathologie, Charité Universitätsmedizin Berlin Campus Mitte, Berlin, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Dietel
authors.affiliation: Pathologisches Institut Mannheim, Mannheim, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Gaiser
authors.affiliation: Pathologisches Institut der Ludwig-Maximilians-Universität München, München, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Kirchner
authors.affiliation: Institut für Pathologie, Medizinische Hochschule Hannover, Hannover, Deutschland.
authors.forename: H H
authors.initials: HH
authors.lastname: Kreipe
authors.affiliation: Institut für Pathologie, Uniklinik Köln, Köln, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Quaas
authors.affiliation: Institut für Pathologie, Christian-Albrechts-Universität, Kiel, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Röcken
authors.affiliation: Institut für Pathologie Nordhessen u. Targos GmbH, Kassel, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Rüschoff
authors.affiliation: Institut für Pathologie der Ruhr-Universität Bochum am Berufsgenossenschaftlichen Universitätsklinikum Bergmannsheil, Georgius Agricola Stiftung Ruhr, Bochum, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Tannapfel
authors.affiliation: Universitäres Krebszentrum (UCCL), Universitätsklinikum Leipzig, Leipzig, Deutschland.
authors.forename: F
authors.initials: F
authors.lastname: Lordick
authors.affiliation: Krankenhaus Nordwest, Frankfurt am Main, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Al-Batran
authors.affiliation: Universitätsmedizin Mannheim, Mannheim, Deutschland.
authors.forename: R
authors.initials: R
authors.lastname: Hofheinz
authors.affiliation: III. Medizinische Klinik, Klinikums rechts der Isar, München, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Lorenzen
authors.affiliation: I. Medizinische Klinik und Poliklinik, Universitätsmedizin Mainz, Mainz, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Moehler
authors.affiliation: CVK: Campus Virchow-Klinikum, Charité Centrum Tumormedizin CC14, Charité - Universitätsmedizin Berlin, Berlin, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Thuss-Patience
mesh_terms: D000230:Adenocarcinoma / Q000235:genetics* / Q000473:pathology / Q000628:therapy; D000465:Algorithms; D001706:Biopsy; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics; D019983:Guideline Adherence; D006801:Humans; D033183:Interdisciplinary Communication; D000070516:Intersectoral Collaboration; D011379:Prognosis; D018719:Erb-b2 Receptor Tyrosine Kinases / Q000235:genetics*; D015203:Reproducibility of Results; D013270:Stomach / Q000473:pathology; D013274:Stomach Neoplasms / Q000235:genetics* / Q000473:pathology / Q000628:therapy
chemical_list: D018719:Erb-b2 Receptor Tyrosine Kinases; C508053:ERBB2 protein, human
keywords: Consensus; Gastric cancer; HER2 testing; Quality assurance; Trastuzumab