title: Osteopathic Approach to the Diagnosis of Appendiceal Mucinous Cystadenocarcinoma Mimicking Primary Ovarian Malignant Neoplasm.
abstract: The fifth leading cause of cancer-related deaths among women in the United States is ovarian cancer. An estimated 21,980 new cases and 14,270 estimated deaths occurred nationwide in 2014. More than two-thirds of cases of ovarian cancer are diagnosed at stage III or IV when the peritoneal cavity or other organs are affected. Primary appendiceal malignant neoplasms may mimic advanced-stage ovarian cancer and can be misdiagnosed because of its presentation as a palpable adnexal mass. The authors describe a 42-year-old woman who was admitted to the department of obstetrics and gynecology to receive treatment for presumed advanced-stage ovarian cancer. She subsequently received a diagnosis of primary pseudomyxoma peritonei metastatic to the ovaries, mimicking a primary ovarian cancer by osteopathic structural examination findings, serum tumor markers, surgical exploration, and histopathologic confirmation.
authors.forename: Daniel
authors.initials: D
authors.lastname: Martingano
authors.forename: Hashroop
authors.initials: H
authors.lastname: Gurm
authors.forename: Andrew
authors.initials: A
authors.lastname: Oliff
authors.forename: Francis X
authors.initials: FX
authors.lastname: Martingano
authors.forename: George
authors.initials: G
authors.lastname: Aglialoro
mesh_terms: D000328:Adult; D001063:Appendiceal Neoplasms / Q000175:diagnosis* / Q000473:pathology; D014408:Biomarkers, Tumor / Q000032:analysis; D001706:Biopsy; D018282:Cystadenocarcinoma, Mucinous / Q000175:diagnosis* / Q000473:pathology; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D010021:Osteopathic Medicine; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary; D019152:Paracentesis
chemical_list: D014408:Biomarkers, Tumor