title: Technical Note: Improving the VMERGE treatment planning algorithm for rotational radiotherapy.
abstract: OBJECTIVE
  The authors revisit the VMERGE treatment planning algorithm by Craft et al. ["Multicriteria VMAT optimization," Med. Phys. 39, 686-696 (2012)] for arc therapy planning and propose two changes to the method that are aimed at improving the achieved trade-off between treatment time and plan quality at little additional planning time cost, while retaining other desirable properties of the original algorithm.
  
  
  METHODS
  The original VMERGE algorithm first computes an "ideal," high quality but also highly time consuming treatment plan that irradiates the patient from all possible angles in a fine angular grid with a highly modulated beam and then makes this plan deliverable within practical treatment time by an iterative fluence map merging and sequencing algorithm. We propose two changes to this method. First, we regularize the ideal plan obtained in the first step by adding an explicit constraint on treatment time. Second, we propose a different merging criterion that comprises of identifying and merging adjacent maps whose merging results in the least degradation of radiation dose.
  
  
  RESULTS
  The effect of both suggested modifications is evaluated individually and jointly on clinical prostate and paraspinal cases. Details of the two cases are reported.
  
  
  CONCLUSIONS
  In the authors' computational study they found that both proposed modifications, especially the regularization, yield noticeably improved treatment plans for the same treatment times than what can be obtained using the original VMERGE method. The resulting plans match the quality of 20-beam step-and-shoot IMRT plans with a delivery time of approximately 2 min.
authors.affiliation: Department of Mathematics, North Carolina State University, Raleigh, North Carolina 27695-8205.
authors.forename: Melissa R
authors.initials: MR
authors.lastname: Gaddy
authors.affiliation: Department of Mathematics, North Carolina State University, Raleigh, North Carolina 27695-8205.
authors.forename: Dávid
authors.initials: D
authors.lastname: Papp
mesh_terms: D000465:Algorithms; D006801:Humans; D008297:Male; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011880:Radiotherapy Planning, Computer-Assisted / Q000379:methods*; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods*; D013120:Spinal Cord Neoplasms / Q000532:radiotherapy; D013997:Time Factors