title: Treatment sequence of synchronously (liver) metastasized colon cancer.
abstract: No standards for staging, systemic therapy or the timing of an operation are defined for patients newly diagnosed with synchronous metastases and a primary in the colon. An expert group of radiologists, medical, radiation and surgical oncologists therefore came together to discuss staging and treatment sequence for these patients and came up with a recommendation based on current evidence of potential therapeutic options. The discussion was organized to debate recommendations centred on 5 topics and therefore the position paper is built upon these titles and their subtitles.
authors.affiliation: Department of Surgery I, Rudolfstiftung Hospital, Vienna, Austria. Electronic address: tgruenberger@icloud.com.
authors.forename: Thomas
authors.initials: T
authors.lastname: Gruenberger
authors.affiliation: Department of Surgery, Netherlands Cancer Institute, Amsterdam, The Netherlands.
authors.forename: Geerard
authors.initials: G
authors.lastname: Beets
authors.affiliation: Department of Gastroenterology - GI Cancer Unit, Erasme University Hospital, Brussels, Belgium.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Van Laethem
authors.affiliation: Digestive Oncology Department, NanteJean-YvesBir, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Rougier
authors.affiliation: Dept. Medical Oncology, Biomedical Research Institute INCLIVA, University of Valencia, Spain.
authors.forename: Andrés
authors.initials: A
authors.lastname: Cervantes
authors.affiliation: Integrated Center of Oncology (ICO), R Gauducheau, St Herblain, France.
authors.forename: Jean-Yves
authors.initials: JY
authors.lastname: Douillard
authors.affiliation: Hepato-biliary and Pancreatic Unit, Josep Trueta Hospital, Girona, Spain.
authors.forename: Joan
authors.initials: J
authors.lastname: Figueras
authors.affiliation: Department of Internal Medicine, Hospital of St. John of God, Vienna, Austria.
authors.forename: Birgit
authors.initials: B
authors.lastname: Gruenberger
authors.affiliation: Abramson Cancer Center University of Pennsylvania, Philadelphia, USA.
authors.forename: Daniel G
authors.initials: DG
authors.lastname: Haller
authors.affiliation: Cancer Center Ospedale Papa Giovanni XXIII, Bergamo, Italy.
authors.forename: Roberto
authors.initials: R
authors.lastname: Labianca
authors.affiliation: Department of Radiology, University Hospitals Leuven, Belgium.
authors.forename: Geert
authors.initials: G
authors.lastname: Maleux
authors.affiliation: Oncology Department, Geneva University Hospitals, Switzerland.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Roth
authors.affiliation: Department of Medical Oncology, Gustave Roussy, Villejuif, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Ducreux
authors.affiliation: Department of Medicine, Ruhr University Bochum, Knappschaftskrankenhaus, Germany.
authors.forename: Wolff
authors.initials: W
authors.lastname: Schmiegel
authors.affiliation: Clinic of Internal Medicine I, University Hospital Ulm, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Seufferlein
authors.affiliation: Digestive Oncology, University Hospitals Leuven and KULeuven, Leuven, Belgium.
authors.forename: Eric
authors.initials: E
authors.lastname: Van Cutsem
mesh_terms: D024221:Antineoplastic Protocols; D003106:Colon / Q000473:pathology; D015179:Colorectal Neoplasms / Q000473:pathology* / Q000628:therapy*; D003131:Combined Modality Therapy; D004358:Drug Therapy; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000473:pathology; D008113:Liver Neoplasms / Q000556:secondary* / Q000628:therapy*; D009367:Neoplasm Staging
keywords: Colorectal cancer; Liver metastases; Synchronous presentation; Treatment options