title: Effect of aerobic exercise and raloxifene combination therapy on senile osteoporosis.
abstract: [Purpose] This study assessed the effects of combined application of raloxifene and aerobic exercise on senile osteoporosis. [Subjects and Methods] A total of 70 elderly patients with osteoporosis, who treated at our hospital between April 2013 and August 2014, were divided into equal-sized observation and control groups. The control group was administered raloxifene, whereas the observation group received raloxifene treatment plus aerobic exercise. [Results] Outpatient outcomes were considered dependent variables. After treatment, the two groups differed significantly in terms of lumbar spine (L2-L4) and proximal femoral bone mineral density. The urine pyridine/creatinine ratio decreased significantly and serum calcitonin level increased significantly in the observation group. These differences were statistically significant. [Conclusion] Raloxifene combined with aerobic exercise therapy significantly improves bone density and promotes bone formation in patients with senile osteoporosis.
authors.affiliation: School of Medicine, Xi'an Jiaotong University, China; Department of Orthopedic Surgery, Yan'an University Affiliated Hospital, China.
authors.forename: Chengjin
authors.initials: C
authors.lastname: Zhao
authors.affiliation: Department of Orthopedic Surgery, Yan'an University Affiliated Hospital, China.
authors.forename: Haibing
authors.initials: H
authors.lastname: Hou
authors.affiliation: Department of Orthopedic Surgery, Yan'an University Affiliated Hospital, China.
authors.forename: Yutao
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Yan'an Traditional Chinese Hospital of Shanxi Province, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Lv
keywords: Aerobic exercise; Elderly; Raloxifene