title: The Difference in Heart Rate Change between Temporal and Frontal Lobe Seizures during Peri-ictal Period.
abstract: OBJECTIVE
  Heart rate (HR) change is easily seen in seizures. Tachycardia is frequently seen in temporal lobe epilepsy (TLE), rather than extra temporal lobe epilepsy (XTLE). We report the difference in the HR pattern between TLE and frontal lobe epilepsy (FLE) during peri-ictal period.
  
  
  METHODS
  The ECG data, collected during EEG monitoring, was used. To compare the HR pattern between FLE and TLE, we investigated the baseline HR, maximum HR, seizure onset to peak HR, HR change, and the time return to baseline.
  
  
  RESULTS
  A total of 198 seizures (FLE was 115, TLE was 83) were included in this study. The baseline HR (in TLE, 74.9 ± 17.2 and in FLE, 70.7 ± 11.5 bpm), there was no difference between two groups. But the mean duration of the increased HR was more prolonged in TLE group (93.8 ± 54.9 seconds) than the FLE group(39.0 ± 21.4 seconds) (p < 0.001), the time to peak HR of the TLE group (135.1 ± 19.1 seconds) was higher than FLE group (119.3 ± 19.7 seconds) (p = 0.027), and the HR change of the TLE group (60.0 ± 26.3 bpm) was more prominent than that of the FLE group (22.8 ± 26.2 seconds) (p < 0.001). Furthermore, a longer duration of HR increase was seen in that of the TLE group than FLE group.
  
  
  CONCLUSIONS
  The HR change of the TLE group was more prominent and prolonged than that of the FLE group. Therefore, the HR change can be a pattern that differentiates TLE from FLE.
authors.affiliation: Department of Neurology, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine;
authors.forename: Woo Hyun
authors.initials: WH
authors.lastname: Son
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Woo Sub
authors.initials: WS
authors.lastname: Hwang
authors.affiliation: Department of Neurology, Seoul Metropolitan Government Seoul National University Borame Medical Center, Seoul National University College of Medicine;
authors.forename: Dae Lim
authors.initials: DL
authors.lastname: Koo
authors.affiliation: Department of Neurology, Kyunghee University Hospital, Kyunghee University School of Medicine, Seoul;
authors.forename: Kyoung Jin
authors.initials: KJ
authors.lastname: Hwang
authors.affiliation: Department of Neurology, Chungnam National University Hospital, Chungnam National University School of Medicine, Daejeon, Korea.
authors.forename: Dae Yung
authors.initials: DY
authors.lastname: Kim
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Ji-Hye
authors.initials: JH
authors.lastname: Seo
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Geon-Youb
authors.initials: GY
authors.lastname: Na
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Eun Yeon
authors.initials: EY
authors.lastname: Joo
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Seung Bong
authors.initials: SB
authors.lastname: Hong
authors.affiliation: Department of Neurology, Samsung Medical Center, Sungkyunkwan University School of Medicine;
authors.forename: Dae-Won
authors.initials: DW
authors.lastname: Seo
keywords: Epilepsy; Frontal lobe; Heart rate; Seizure; Temporal lobe