title: Introduction to biosensors.
abstract: Biosensors are nowadays ubiquitous in biomedical diagnosis as well as a wide range of other areas such as point-of-care monitoring of treatment and disease progression, environmental monitoring, food control, drug discovery, forensics and biomedical research. A wide range of techniques can be used for the development of biosensors. Their coupling with high-affinity biomolecules allows the sensitive and selective detection of a range of analytes. We give a general introduction to biosensors and biosensing technologies, including a brief historical overview, introducing key developments in the field and illustrating the breadth of biomolecular sensing strategies and the expansion of nanotechnological approaches that are now available.
authors.affiliation: Department of Electronic and Electrical Engineering, University of Bath, Bath BA2 7AY, U.K.
authors.forename: Nikhil
authors.initials: N
authors.lastname: Bhalla
authors.affiliation: Department of Electronic and Electrical Engineering, University of Bath, Bath BA2 7AY, U.K.
authors.forename: Pawan
authors.initials: P
authors.lastname: Jolly
authors.affiliation: Department of Electronic and Electrical Engineering, University of Bath, Bath BA2 7AY, U.K.
authors.forename: Nello
authors.initials: N
authors.lastname: Formisano
authors.affiliation: Department of Electronic and Electrical Engineering, University of Bath, Bath BA2 7AY, U.K. p.estrela@bath.ac.uk.
authors.forename: Pedro
authors.initials: P
authors.lastname: Estrela
mesh_terms: D000669:Amplifiers, Electronic; D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques / Q000266:history / Q000379:methods*; D004800:Enzymes, Immobilized / Q000737:chemistry; D049673:History, 20th Century; D049674:History, 21st Century; D015398:Signal Transduction
chemical_list: D052157:Aptamers, Nucleotide; D004800:Enzymes, Immobilized
keywords: affinity reagents; biosensors; glucose sensor; nanomaterials; pregnancy test