title: Iodine-Mediated Domino Oxidative Cyclization: One-Pot Synthesis of 1,3,4-Oxadiazoles via Oxidative Cleavage of C(sp(2))-H or C(sp)-H Bond.
abstract: An I2-promoted, metal-free domino protocol for one-pot synthesis of 1,3,4-oxadiazoles has been developed via oxidative cleavage of C(sp(2))-H or C(sp)-H bonds, followed by cyclization and deacylation. In this reaction, the use of K2CO3 as a base is found to be an essential factor in the cyclization and the C-C bond cleavage. This procedure proceeded smoothly in moderate to high yields with good functional group compatibility.
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Yuxing
authors.initials: Y
authors.lastname: Fan
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Yongqin
authors.initials: Y
authors.lastname: He
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Xingxing
authors.initials: X
authors.lastname: Liu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Ting
authors.initials: T
authors.lastname: Hu
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Haojie
authors.initials: H
authors.lastname: Ma
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Xinliang
authors.initials: X
authors.lastname: Luo
authors.affiliation: State Key Laboratory of Applied Organic Chemistry, Lanzhou University , Lanzhou, Gansu, 730000, P. R. China.|Key Laboratory of Nonferrous Metal Chemistry and Resources Utilization of Gansu Province , Lanzhou, 730000, P. R. China.
authors.forename: Guosheng
authors.initials: G
authors.lastname: Huang