title: Intraoperative Ephedrine Allergy in a Patient Who Received Chemotherapy and Perioperative Hypersensitivity Reactions.
abstract: Anaesthesia represents a specific set-up in respect to pharmacology, and during this time, early hypersensitivity reactions or anaphylaxis may occur in patients who are exposed to a great number of foreign substances. Intravenous ephedrine (5 mg) was applied to a 37-year-old patient due to the development of intraoperative hypotension in a total abdominal hysterectomy operation. After application, hyperaemia was seen in the track of the intravenous catheter of that extremity. Approximately 15 minutes later, urticarial plaques were observed extensively in the abdomen and in both extremities. Methylprednisolone (100 mg+100 mg) and pheniramine (45.5 mg) were given with an increasing infusion rate of intravenous crystalloid. The patient was extubated without any problem and removed to the recovery unit for observation. After the total disappearance of lesions at postoperative 60 minutes and because of the stability of vital signs, the patient was removed to the service. In the follow-up of surgery, no complication developed, and the patient was discharged on postoperative day 2.
authors.affiliation: Department of Anaesthesiology and Reanimation, Mustafa Kemal University Faculty of Medicine, Hatay, Turkey.
authors.forename: Sedat
authors.initials: S
authors.lastname: Hakimoğlu
authors.affiliation: Department of Anaesthesiology and Reanimation, Mustafa Kemal University Faculty of Medicine, Hatay, Turkey.
authors.forename: Kasım
authors.initials: K
authors.lastname: Tuzcu
authors.affiliation: Department of Anaesthesiology and Reanimation, Mustafa Kemal University Faculty of Medicine, Hatay, Turkey.
authors.forename: Işıl
authors.initials: I
authors.lastname: Davarcı
authors.affiliation: Department of Anaesthesiology and Reanimation, Mustafa Kemal University Faculty of Medicine, Hatay, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Karcıoğlu
authors.affiliation: Department of Gynecology and Obstetrics, Mustafa Kemal University Faculty of Medicine, Hatay, Turkey.
authors.forename: Raziye
authors.initials: R
authors.lastname: Kurt
authors.affiliation: Department of Anaesthesiology and Reanimation, Mustafa Kemal University Faculty of Medicine, Hatay, Turkey.
authors.forename: İsmail
authors.initials: İ
authors.lastname: Dikey
keywords: Ephedrine; hypersensitivity reactions; intraoperative