title: Outbreak of mortality in Russian (Acipenser gueldenstaedtii) and Siberian (Acipenser baerii) sturgeons associated with sturgeon nucleo-cytoplasmatic large DNA virus.
abstract: Diseased outbreaks with high mortality in farmed sturgeon are a limiting factor to the success of this emerging aquaculture sector in Europe. Thorough investigations of outbreaks can determine the aetiological agents, identify important pathological and epidemiological pathways of infections and pave the way for effective control strategies. A thorough investigation of a mortality outbreak in Russian (Acipenser gueldenstaedtii) and Siberian (Acipenser baerii) sturgeons in Italy, demonstrated the primary involvement of a sturgeon nucleo-cytoplasmic large DNA virus (NCLDV). While, the taxonomy classification of this new virus is still uncertain, its involvement in sturgeon mortality outbreaks in Europe is, for the first time, fully investigated and described. Furthermore, the coinfection of bacteria such as motile Aeromonas spp. and Acinetobacter spp. was reported. Genetic characterisation showed the close relationship between the European sturgeon NCLDV with North American sturgeon NCLDVs. Similarly to the latter, the European sturgeon NCLDV persists in survivors. Furthermore, a systemic distribution of the European sturgeon NCLDV was evident in diseased A. baerii and A. gueldenstaedtii and in recovered A. gueldenstaedtii. These epidemiological and pathological findings will help in the identification of effective control strategies for sturgeon NCLDV infection, which afflicts an important and emerging European aquaculture sector.
authors.affiliation: Department of Veterinary Medical Sciences, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy. Electronic address: sara.ciulli@unibo.it.
authors.forename: S
authors.initials: S
authors.lastname: Ciulli
authors.affiliation: Department of Veterinary Medical Sciences, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy.
authors.forename: E
authors.initials: E
authors.lastname: Volpe
authors.affiliation: Department of Veterinary Medical Sciences, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Sirri
authors.affiliation: Department of Veterinary Medical Sciences, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy.
authors.forename: P L
authors.initials: PL
authors.lastname: Passalacqua
authors.affiliation: Cesena Campus, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Cesa Bianchi
authors.affiliation: Department of Veterinary Medical Sciences, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Serratore
authors.affiliation: Department of Veterinary Medical Sciences, University of Bologna, Viale Vespucci, 2, 47042 Cesenatico, FC, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Mandrioli
mesh_terms: D000595:Amino Acid Sequence; D000818:Animals; D017756:Aquaculture; D036022:Capsid Proteins / Q000737:chemistry / Q000235:genetics; D004266:DNA Virus Infections / Q000453:epidemiology / Q000401:mortality / Q000662:veterinary* / Q000821:virology; D004267:DNA Viruses / Q000145:classification* / Q000235:genetics / Q000502:physiology; D004196:Disease Outbreaks; D005393:Fish Diseases / Q000453:epidemiology* / Q000401:mortality* / Q000517:prevention & control / Q000821:virology; D005399:Fishes; D007558:Italy / Q000453:epidemiology; D010802:Phylogeny; D012426:Russia / Q000453:epidemiology
chemical_list: D036022:Capsid Proteins
keywords: Acinetobacter spp.; Acipenser baerii; Acipenser gueldenstaedtii; Mortality outbreak; Sturgeon nucleo-cytoplasmic large DNA virus