title: Formation Mechanism of Monodehydro-l-ascorbic Acid and Superoxide Anion in the Autoxidation of l-Ascorbic Acid.
abstract: The oxidation of l-ascorbic acid (ASA) by molecular oxygen was studied in the absence of heavy metal ion catalysts. The formation of superoxide anion was confirmed during the autoxidation of ASA not only in aqueous solution but also in MeOH. The formation mechanism of superoxide anion was discussed based on both experimental and molecular orbital (MO) calculation results. It was proposed that ASA autoxidation proceeded via the C(2) oxygen adduct of ASA, and superoxide anion would be directly released from the C(2) oxygen adduct of ASA, forming monodehydro-ASA (MDASA).
authors.affiliation: a Institute of Environmental Science for Human Life , Ochanomizu University , Bunkyo-ku, Tokyo 112 , Japan.
authors.forename: N
authors.initials: N
authors.lastname: Miyake
authors.affiliation: a Institute of Environmental Science for Human Life , Ochanomizu University , Bunkyo-ku, Tokyo 112 , Japan.
authors.forename: M
authors.initials: M
authors.lastname: Kim
authors.affiliation: a Institute of Environmental Science for Human Life , Ochanomizu University , Bunkyo-ku, Tokyo 112 , Japan.
authors.forename: T
authors.initials: T
authors.lastname: Kurata
keywords: autoxidation; l-ascorbic acid; monodehydro-l-ascorbic acid; oxygen adduct of l-ascorbic acid; superoxide anion