title: Role of Durable Mechanical Circulatory Support for the Management of Advanced Heart Failure.
abstract: In the past decade, there has been a dramatic evolution in the field of mechanical circulatory support. Device-related complications continue to burden the field and will be a major obstacle for achieving therapeutic noninferiority compared with cardiac transplant. Selected patients with end-stage systolic heart failure enjoy an average survival of 80% at 1 year post-ventricular assist device implant, vastly better than survival rates of 25% to 50% on chronic inotrope support. Early patient referral to an advanced heart failure specialist before the onset of significant end-organ dysfunction and malnutrition is critical for achieving good operative outcomes.
authors.affiliation: St. Vincent Heart Center of Indiana, Indianapolis, IN 46260, USA.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Waqas
authors.affiliation: St. Vincent Heart Center of Indiana, Indianapolis, IN 46260, USA. Electronic address: jennifercowger@gmail.com.
authors.forename: Jennifer A
authors.initials: JA
authors.lastname: Cowger
mesh_terms: D001243:Assisted Circulation / Q000009:adverse effects / Q000295:instrumentation* / Q000639:trends; D019468:Disease Management; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery*; D016027:Heart Transplantation; D006353:Heart-Assist Devices / Q000009:adverse effects*; D006801:Humans; D018579:Patient Selection; D012307:Risk Factors; D015996:Survival Rate; D016896:Treatment Outcome
keywords: Advanced heart failure management; Mechanical circulatory support; Outcomes