title: Thrombotic microangiopathy as an initial manifestation in HIV patients.
abstract: Thrombotic microangiopathy (TMA) is characterized by microangiopathic hemolytic anemia, thrombocytopenia, microvascular thrombosis, and various organ dysfunctions. TMA usually occurs in a more advanced stage of HIV disease. TMA as an initial presenting feature is rare. We here report a male patient who presented with oliguric renal failure. Investigations revealed anemia, thrombocytopenia, schistocytes in peripheral smear, and HIV-positive. Renal biopsy revealed TMA. He was treated with hemodialysis and started on highly active antiretroviral therapy.
authors.affiliation: Department of Nephrology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.
authors.forename: Thanigachalam
authors.initials: T
authors.lastname: Dineshkumar
authors.affiliation: Department of Nephrology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.
authors.forename: Jeyachandran
authors.initials: J
authors.lastname: Dhanapriya
authors.affiliation: Department of Nephrology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.
authors.forename: Palanivel
authors.initials: P
authors.lastname: Jaganathan
authors.affiliation: Department of Nephrology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.
authors.forename: Ramanathan
authors.initials: R
authors.lastname: Sakthirajan
authors.affiliation: Department of Nephrology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.
authors.forename: Natarajan
authors.initials: N
authors.lastname: Gopalakrishnan
authors.affiliation: Department of Nephrology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India.
authors.forename: T
authors.initials: T
authors.lastname: Balasubramaniyan
keywords: Antiretroviral therapy; HIV; renal failure; thrombotic microangiopathy