title: Quantification of Monoclonal Immunoglobulins by Immunochemical and Densitometry Techniques.
abstract: In comparing four currently available immunochemical methods for immunoglobulin quantification, i.e. radial immunodiffusion (RID), rate nephelometry (RN), laser nephelometry (LN) and turbidimetry (T), highly divergent results were obtained for monoclonal immunoglobulins. Comparison with data obtained by densitometric scanning (D) of the serum protein electrophoresis on cellulose acetate showed that these immunochemical techniques cannot be recommended for the quantification of monoclonal immunoglobulins, they may however remain useful for assessing relative changes in concentration during treatment.
authors.affiliation: a Department of Clinical Chemistry.
authors.forename: F
authors.initials: F
authors.lastname: Gorus
authors.affiliation: a Department of Clinical Chemistry.
authors.forename: S
authors.initials: S
authors.lastname: Stesses
authors.affiliation: b Department of Haematology Akademisch Ziekenhuis Vrije Universiteit Brussel , Laarbeeklaan 101 B 1090 Brussel , Belgie.
authors.forename: B V
authors.initials: BV
authors.lastname: Camp