title: Tricyclic antidepressant overdose treated with adjunctive lipid rescue and plasmapheresis.
abstract: Tricyclic antidepressant poisoning remains a major cause of morbidity and mortality, particularly in the setting of suicidal attempts. The current standard of care for treatment is the administration of sodium bicarbonate infusion. Adjunctive lipid emulsion therapy and plasmapheresis have received attention recently. We report an 18-year-old patient who was successfully managed with lipid emulsion and plasmapheresis as adjuncts to sodium bicarbonate treatment and review some of the recent literature.
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Chibuzo Clement
authors.initials: CC
authors.lastname: Odigwe
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Madiha
authors.initials: M
authors.lastname: Tariq
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Tulsi
authors.initials: T
authors.lastname: Kotecha
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Usman
authors.initials: U
authors.lastname: Mustafa
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Nizar
authors.initials: N
authors.lastname: Senussi
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Isaac
authors.initials: I
authors.lastname: Ikwu
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Anirban
authors.initials: A
authors.lastname: Bhattarcharya
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: John Ifeanyi
authors.initials: JI
authors.lastname: Ngene
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Kizito
authors.initials: K
authors.lastname: Ojiako
authors.affiliation: Department of Medicine, St. Joseph Hospital, Chicago, Illinois.
authors.forename: Nkemakolam
authors.initials: N
authors.lastname: Iroegbu