title: Flavonol glycosides from the aerial parts of Gynostemma pentaphyllum and their antioxidant activity.
abstract: The phytochemical investigation of the aerial parts of Gynostemma pentaphyllum led to the isolation of a new flavonol glycoside, gynopentaphylloside (1), along with seven known compounds (2-8). The structure of the new compound was determined on the basis of 1D, 2D NMR and HRESIMS data as well as acid hydrolysis. The antioxidant activity of the isolates was evaluated by a 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging assay.
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Hari
authors.initials: H
authors.lastname: Jang
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Jin Woo
authors.initials: JW
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Chul
authors.initials: C
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Qinghao
authors.initials: Q
authors.lastname: Jin
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Myung Koo
authors.initials: MK
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Chong Kil
authors.initials: CK
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea.
authors.forename: Mi Kyeong
authors.initials: MK
authors.lastname: Lee
authors.affiliation: College of Pharmacy, Chungbuk National University, Cheongju, 28644, Republic of Korea. byhwang@chungbuk.ac.kr.
authors.forename: Bang Yeon
authors.initials: BY
authors.lastname: Hwang
mesh_terms: D000975:Antioxidants / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D044948:Flavonols / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D016166:Free Radical Scavengers / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology; D006027:Glycosides / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology; D029774:Gynostemma; D010084:Oxidation-Reduction / Q000187:drug effects; D035261:Plant Components, Aerial; D010936:Plant Extracts / Q000737:chemistry* / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D000975:Antioxidants; D044948:Flavonols; D016166:Free Radical Scavengers; D006027:Glycosides; D010936:Plant Extracts
keywords: Antioxidant activity; Cucurbitaceae; Flavonol glycoside; Gynostemma pentaphyllum