title: Retinal Image Enhancement Using Robust Inverse Diffusion Equation and Self-Similarity Filtering.
abstract: As a common ocular complication for diabetic patients, diabetic retinopathy has become an important public health problem in the world. Early diagnosis and early treatment with the help of fundus imaging technology is an effective control method. In this paper, a robust inverse diffusion equation combining a self-similarity filtering is presented to detect and evaluate diabetic retinopathy using retinal image enhancement. A flux corrected transport technique is used to control diffusion flux adaptively, which eliminates overshoots inherent in the Laplacian operation. Feature preserving denoising by the self-similarity filtering ensures a robust enhancement of noisy and blurry retinal images. Experimental results demonstrate that this algorithm can enhance important details of retinal image data effectively, affording an opportunity for better medical interpretation and subsequent processing.
authors.affiliation: School of Public Health, Shandong University, Jinan 250012, China.
authors.forename: Lu
authors.initials: L
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Qilu Children's Hospital of Shandong University, Jinan 250022, China.
authors.forename: Guohua
authors.initials: G
authors.lastname: Liu
authors.affiliation: School of Mathematics, Shandong University, Jinan 250100, China.
authors.forename: Shujun
authors.initials: S
authors.lastname: Fu
authors.affiliation: School of Public Health, Shandong University, Jinan 250012, China.
authors.forename: Lingzhong
authors.initials: L
authors.lastname: Xu
authors.affiliation: Department of Medical Imaging, The Second Hospital of Shandong University, Jinan 250033, China.
authors.forename: Kun
authors.initials: K
authors.lastname: Zhao
authors.affiliation: School of Computer Science and Technology, Shandong University of Finance and Economics, Jinan 250061, China.|School of Computer Science and Technology, Shandong University, Jinan 250101, China.
authors.forename: Caiming
authors.initials: C
authors.lastname: Zhang
mesh_terms: D000465:Algorithms; D016477:Artifacts; D003116:Color; D003930:Diabetic Retinopathy / Q000000981:diagnostic imaging*; D004058:Diffusion; D005654:Fundus Oculi; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods; D007091:Image Processing, Computer-Assisted; D000071071:Microaneurysm / Q000503:physiopathology; D008962:Models, Theoretical; D016011:Normal Distribution; D012160:Retina / Q000000981:diagnostic imaging* / Q000503:physiopathology