title: Risk-benefit assessment for antibiotic prophylaxis in asplenic dental patients.
abstract: A review of the published literature revealed that discourse on the topic of antibiotic prophylaxis guidelines for the asplenic dental patient is limited and that guidelines regarding this issue have not been updated for years. The review determined that the professional protocol for the treatment of asplenic dental patients has changed over the last 30 years, particularly with reference to adult patients. Furthermore, as dentists and physicians now understand that blood-borne bacteremias are produced from everyday occurrences such as chewing and toothbrushing, bacteremias secondary to dental procedures are no longer viewed as seriously as in the past; therefore, the guidelines for antibiotic prophylaxis have changed. Antibiotic prophylaxis is not routinely indicated prior to dental procedures for asplenic adult dental patients without risk factors. However, antibiotic prophylaxis should be considered for young children, immunocompromised patients with underlying causative disease, or any patient during the first 3 years after a splenectomy.
authors.forename: Heba
authors.initials: H
authors.lastname: Hussein
authors.forename: Ronald S
authors.initials: RS
authors.lastname: Brown
mesh_terms: D019072:Antibiotic Prophylaxis / Q000009:adverse effects / Q000379:methods / Q000592:standards; D003729:Dental Care / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D006801:Humans; D017410:Practice Guidelines as Topic; D018570:Risk Assessment; D012307:Risk Factors; D013154:Spleen / Q000502:physiology; D013156:Splenectomy / Q000009:adverse effects*
keywords: antibiotic prophylaxis; asplenic; dentistry; splenectomy