title: Assessment of Retinal and Choroidal Measurements in Chinese School-Age Children with Cirrus-HD Optical Coherence Tomography.
abstract: OBJECTIVE
  To evaluate retinal thickness (RT), retinal volume (RV) and choroidal thickness (ChT) in Chinese children using Cirrus-HD optical coherence tomography (OCT), and assess their associations with spherical equivalent (SE), age and gender.
  
  
  METHODS
  This was a prospective study that recruited 193 healthy Chinese children (193 eyes) with no ophthalmic disease history between December 2012 and December 2013. RT and RV were acquired using OCT. Subfoveal ChT (SFCT) and ChT1-mm and 2-mm temporal, nasal, superior and inferior to the fovea were measured manually.
  
  
  RESULTS
  RT in the inner temporal and nasal regionsdiffered significantly between refraction groups (both P<0.05). Significant differences were also found inSFCT andChT 1- and 2-mm inferior to the fovea (all P<0.05). RT differed significantly between males and females in the outer superior region in the emmetropia group (P<0.05). ChT differed significantly between males and females 2-mm temporal to the fovea in the emmetropia group (P<0.05), and 1-mm temporal to the fovea in the mild myopia group (P<0.05). SE correlated positively with RT in the inner temporal (r = 0.230),nasal (r = 0.252) and inferior (r = 0.149) regions (all P<0.05). Age correlated positively with foveolar (r = 0.169), total macular (r = 0.202), inner temporal (r = 0.237), inner nasal (r = 0.248), inner superior (r = 0.378) and inner inferior (r = 0.345) region thicknesses, and with RV (r = 0.207)(all P<0.05). SE correlated positively with SFCT (r = 0.195), and with ChT1-mm temporal (r = 0.167), 1- and 2-mm nasal (r = 0.144 and r = 0.162), 2-mm superior (r = 0.175), and 1- and 2-mm inferior (r = 0.207 and r = 0.238) to the fovea (all P<0.05). Age had no significant association with ChT.
  
  
  CONCLUSIONS
  SE, age and gender did not influence macular RT and ChT in most regions, and correlations of RT with age and ChT with SE were weak.
authors.affiliation: Department of Ophthalmology, Fudan University Jinshan Hospital and, 1508 Longhang Road, Shanghai, China.
authors.forename: Tao
authors.initials: T
authors.lastname: Li
authors.affiliation: Department of Ophthalmology, Fudan University Jinshan Hospital and, 1508 Longhang Road, Shanghai, China.
authors.forename: Xiaodong
authors.initials: X
authors.lastname: Zhou
authors.affiliation: Department of Ophthalmology, Fudan University Jinshan Hospital and, 1508 Longhang Road, Shanghai, China.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Department of Ophthalmology, Fudan University Jinshan Hospital and, 1508 Longhang Road, Shanghai, China.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhu
authors.affiliation: Department of Ophthalmology, Fudan University Jinshan Hospital and, 1508 Longhang Road, Shanghai, China.
authors.forename: Wenli
authors.initials: W
authors.lastname: Shen
authors.affiliation: Department of Ophthalmology, Fudan University Jinshan Hospital and, 1508 Longhang Road, Shanghai, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Jiang
mesh_terms: D000293:Adolescent; D044466:Asian People; D002648:Child; D002829:Choroid / Q000000981:diagnostic imaging*; D005260:Female; D006801:Humans; D008297:Male; D011446:Prospective Studies; D012160:Retina / Q000000981:diagnostic imaging*; D012727:Sex Characteristics; D041623:Tomography, Optical Coherence