title: Diagnosis and mortality in prehospital emergency patients transported to hospital: a population-based and registry-based cohort study.
abstract: Knowledge about patients after calling for an ambulance is limited to subgroups, such as patients with cardiac arrest, myocardial infarction, trauma and stroke, while population-based studies including all diagnoses are few. We examined the diagnostic pattern and mortality among all patients brought to hospital by ambulance after emergency calls.
  
  
  
  Registry-based cohort study.
  
  
  
  We included patients brought to hospital in an ambulance dispatched after emergency calls during 2007-2014 in the North Denmark Region (580 000 inhabitants). We reported hospital diagnosis according to the chapters of the International Classification of Diseases, 10th Edition (ICD-10), and studied death on days 1 and 30 after the call. Cohort characteristics and diagnoses were described, and the Kaplan-Meier method was used to estimate mortality and 95% CIs.
  
  
  
  In total, 148 757 patients were included, mean age 52.9 (SD 24.3) years. The most frequent ICD-10 diagnosis chapters were: 'injury and poisoning' (30.0%), and the 2 non-specific diagnosis chapters: 'symptoms and abnormal findings, not elsewhere classified' (17.5%) and 'factors influencing health status and contact with health services' (14.1%), followed by 'diseases of the circulatory system' (10.6%) and 'diseases of the respiratory system' (6.7%). The overall 1-day mortality was 1.8% (CI 1.7% to 1.8%) and 30-day mortality 4.7% (CI 4.6% to 4.8%). 'Diseases of the circulatory system' had the highest 1-day mortality of 7.7% (CI 7.3% to 8.1%) accounting for 1209 deaths. After 30 days, the highest number of deaths were among circulatory diseases (2313), respiratory diseases (1148), 'symptoms and abnormal findings, not elsewhere classified' (1119) and 'injury and poisoning' (741), and 30 days mortality in percentage was 14.7%, 11.6%, 4.3% and 1.7%, respectively.
  
  
  
  Patients' diagnoses from hospital stay after calling 1-1-2 in this population-based study were distributed across all ICD-10 chapters. Mortality varied widely between diagnostic groups. Non-specific diagnoses accounted for one-third of the patients and contributed to mortality in terms of total number of deaths.
authors.affiliation: Department of Clinical Medicine, Pre-hospital and Emergency Research, Aalborg University, Aalborg, Denmark Department of Anaesthesiology and Intensive Care, Aalborg University Hospital, Aalborg, Denmark Prehospital Emergency Medical Services, North Denmark Region, Aalborg, Denmark.
authors.forename: Erika Frischknecht
authors.initials: EF
authors.lastname: Christensen
authors.affiliation: Department of Clinical Medicine, Pre-hospital and Emergency Research, Aalborg University, Aalborg, Denmark Unit of Business Intelligence, North Denmark Region, Aalborg, Denmark.
authors.forename: Thomas Mulvad
authors.initials: TM
authors.lastname: Larsen
authors.affiliation: Prehospital Emergency Medical Services, North Denmark Region, Aalborg, Denmark.
authors.forename: Flemming Bøgh
authors.initials: FB
authors.lastname: Jensen
authors.affiliation: Department of Clinical Medicine, Pre-hospital and Emergency Research, Aalborg University, Aalborg, Denmark Unit of Clinical Biostatistics and Bioinformatics, Aalborg University Hospital, Aalborg, Denmark.
authors.forename: Mette Dahl
authors.initials: MD
authors.lastname: Bendtsen
authors.affiliation: Prehospital Emergency Medical Services, North Denmark Region, Aalborg, Denmark.
authors.forename: Poul Anders
authors.initials: PA
authors.lastname: Hansen
authors.affiliation: Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Søren Paaske
authors.initials: SP
authors.lastname: Johnsen
authors.affiliation: Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark.
authors.forename: Christian Fynbo
authors.initials: CF
authors.lastname: Christiansen
mesh_terms: D000328:Adult; D000368:Aged; D000552:Ambulances; D002318:Cardiovascular Diseases / Q000401:mortality; D002423:Cause of Death; D015331:Cohort Studies; D003718:Denmark; D004632:Emergency Medical Services; D005260:Female; D006760:Hospitalization; D006761:Hospitals; D006801:Humans; D038801:International Classification of Diseases; D008297:Male; D008875:Middle Aged; D011041:Poisoning / Q000401:mortality; D012042:Registries; D012140:Respiratory Tract Diseases / Q000401:mortality; D014947:Wounds and Injuries / Q000401:mortality
keywords: Ambulances; Diagnosis; Emergency Medical Services; Survival