title: ACUTE POSTERIOR MULTIFOCAL PLACOID PIGMENT EPITHELIOPATHY FOLLOWING INFLUENZA VACCINATION.
abstract: OBJECTIVE
  To report a case of acute posterior multifocal placoid pigment epitheliopathy (APMPPE), following influenza vaccination.
  
  
  METHODS
  An 18-year-old female patient developed a painless significant bilateral decrease of vision, moderate photophobia, metamorphopsia and intermittent headaches two weeks after having a seasonal anti-flu immunization. Clinical evaluation and ancillary testing pointed toward the diagnosis of APMPPE. The case evolved favorable after oral prednisone 0.5 mg/kg/day gradually decreased for over 4 weeks. A total recovery of visual function and no recurrences were noticed at 1, 3 and 5 years follow-up.
  
  
  CONCLUSIONS
  Previous case reports already suggested a possible relationship between various immunizations and APMPPE onset. This case is the first one reported in our country. Epidemiological studies are required to link APMPPE occurrence and vaccination.
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D002833:Choroiditis / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D005260:Female; D005938:Glucocorticoids / Q000627:therapeutic use; D006801:Humans; D007252:Influenza Vaccines / Q000009:adverse effects*; D007251:Influenza, Human / Q000517:prevention & control; D000080364:Multifocal Choroiditis; D010211:Papilledema / Q000175:diagnosis* / Q000188:drug therapy / Q000821:virology*; D010857:Pigment Epithelium of Eye / Q000187:drug effects / Q000473:pathology*; D011241:Prednisone / Q000627:therapeutic use; D016896:Treatment Outcome; D014611:Vaccination / Q000009:adverse effects*; D014792:Visual Acuity
chemical_list: D005938:Glucocorticoids; D007252:Influenza Vaccines; D011241:Prednisone