title: Comparing the effects of treatment with sildenafil and cognitive-behavioral therapy on treatment of sexual dysfunction in women: a randomized controlled clinical trial.
abstract: BACKGROUND
  Sexual dysfunction in women is prevalent and common in women after menopause. Many attempts to treat patients with sexual dysfunction by cognitive-behavioral therapy (CBT) methods. But to the best of our knowledge, there has been no study that compared these two methods.
  
  
  OBJECTIVE
  The aim of this study was to assess and compare the effects of sildenafil and cognitive-behavioral therapy on treatment of sexual dysfunction in women.
  
  
  METHODS
  In this randomized, controlled, clinical trial, 86 women with arousal and orgasm dysfunction were surveyed. The patients were divided into two groups, i.e., sildenafil and CBT groups. The patients in the sildenafil group were treated by 50 mg of oral sildenafil one hour before intercourse, and the other group had weekly sessions of CBT for eight weeks. Sexual dysfunctions were evaluated by the Female Sexual Function Index (FSFI), a sexual satisfaction questionnaire, and the Enrich marital satisfaction scale.
  
  
  RESULTS
  The mean age of the participants was 33.14 ± 7.34 years. The mean scores for female sexual function index, sexual satisfaction, and the Enrich marital satisfaction scale were increased in both groups during treatment (p < 0.001). It was found that cognitive-behavioral therapy compared to treatment with sildenafil increased all subscales, except arousal, orgasm, and lubrication.
  
  
  CONCLUSIONS
  Cognitive-behavioral therapy is more effective than treatment with sildenafil for improving female sexual function.
  
  
  BACKGROUND
  The trial was registered at the Iranian Registry of Clinical Trials (http://www.irct.ir) with the IRCT ID: IRCT2014070318338N1.
  
  
  BACKGROUND
  The authors received no financial support for the research, authorship, and/or publication of this article.
authors.affiliation: Ph.D. of Clinical Psychology, Associate Professor, Department of Psychiatry, School of Medicine, Kashan University of Medical Science, Kashan, Iran.
authors.forename: Abdollah
authors.initials: A
authors.lastname: Omidi
authors.affiliation: M.D., Psychiatrist, Associate Professor, Department of Psychiatry, School of Medicine, Kashan University of Medical Science, Kashan, Iran.
authors.forename: Afshin
authors.initials: A
authors.lastname: Ahmadvand
authors.affiliation: M.D., Resident of Psychiatry, Department of Psychiatry, School of Medicine, Iran University of Medical Science, Tehran, Iran.
authors.forename: Mohammad Reza
authors.initials: MR
authors.lastname: Najarzadegan
authors.affiliation: M.D., Resident of Psychiatry, Department of Psychiatry, School of Medicine, Kashan University of Medical Science, Kashan, Iran.
authors.forename: Fateme
authors.initials: F
authors.lastname: Mehrzad
keywords: Cognitive-behavioral therapy; Female arousal disorder; Marital satisfaction; Orgasm; Sildenafil