title: Evaluating arterial stiffness in type 2 diabetes patients using ultrasonic radiofrequency.
abstract: Differences in arterial stiffness between the two sides of the carotid arteries were investigated using ultrasonic radiofrequency in 88 patients with type 2 diabetes and 70 controls. The compliance coefficient (CC), pulse wave velocity (PWV), intima-media thickness (CIMT) and diameter (CCAD) of the common carotid arteries (CCAs) were measured. The ratio of the left to right CCAs was calculated to provide four indexes: CC ratio, PWV ratio, CIMT ratio and CCAD ratio. In the diabetes group, the PWV on the left side was significantly higher than that on the right side, while the CC on the left side was significantly lower than that on the right side. The bilateral CIMT was thicker and CCAD was wider, the left PWV traveled faster, and the right CC was higher in the diabetes group than in the control group. The PWV ratio between the two groups was significantly different and correlated positively with duration of diabetes and systolic blood pressure (SBP). The differences between the two sides of CCAs in patients with diabetes suggested that disease duration and SBP were important risk factors for arterial stiffness. Identifying the difference could potentially lead to the much earlier diagnosis of arteriosclerosis.
authors.affiliation: Department of Ultrasound, Shanghai Jiaotong University, Shanghai, 200080, China.
authors.forename: Zhao-Jun
authors.initials: ZJ
authors.lastname: Li
authors.affiliation: Department of Ultrasound, Shanghai Jiaotong University, Shanghai, 200080, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Ultrasound, Shanghai Jiaotong University, Shanghai, 200080, China.
authors.forename: Lian-Fang
authors.initials: LF
authors.lastname: Du
authors.affiliation: Department of Echocardiography, Shanghai General Hospital, Shanghai Jiaotong University, Shanghai, 200080, China. lxh_20050703@sina.com.
authors.forename: Xiang-Hong
authors.initials: XH
authors.lastname: Luo
mesh_terms: D000328:Adult; D000368:Aged; D001794:Blood Pressure; D017536:Carotid Artery, Common / Q000000981:diagnostic imaging* / Q000503:physiopathology; D059168:Carotid Intima-Media Thickness; D016022:Case-Control Studies; D003924:Diabetes Mellitus, Type 2 / Q000000981:diagnostic imaging* / Q000503:physiopathology; D004452:Echocardiography / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D063177:Pulse Wave Analysis; D012307:Risk Factors; D014465:Ultrasonics; D059289:Vascular Stiffness
keywords: intima-media thickness; pulse wave velocity; stiffness; type 2 diabetes