title: Tacrolimus-associated hemolytic uremic syndrome in a pediatric heart transplant recipient.
abstract: HUS is a well-known entity primarily associated with bacterial infection and is characterized by a classic triad of anemia, thrombocytopenia, and kidney injury. Its atypical form has been associated with calcineurin inhibitors and has been extensively discussed in renal transplantation. We present a case of tacrolimus-associated HUS in a pediatric heart transplant recipient, which we believe to be previously unreported in the literature.
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
authors.forename: James M
authors.initials: JM
authors.lastname: Gray
authors.affiliation: Division of Pediatric Cardiology, Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
authors.forename: Rebecca K
authors.initials: RK
authors.lastname: Ameduri
mesh_terms: D002675:Child, Preschool; D005260:Female; D016027:Heart Transplantation; D006463:Hemolytic-Uremic Syndrome / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects*; D011183:Postoperative Complications / Q000139:chemically induced* / Q000175:diagnosis; D016559:Tacrolimus / Q000009:adverse effects*
chemical_list: D007166:Immunosuppressive Agents; D016559:Tacrolimus
keywords: calcineurin inhibitors; heart transplantation; hemolytic uremic syndrome; pediatrics