title: [Intraocular Pressure Sensor Based on a Contact Lens].
abstract: Intraocular pressure detection has a great significance for understanding the status of eye health, prevention and treatment of diseases such as glaucoma. Traditional intraocular pressure detection needs to be held in the hospital. It is not only time-consuming to doctors and patients, but also difficult to achieve 24 hour-continuous detection. Microminiaturization of the intraocular pressure sensor and wearing it as a contact lens, which is convenient, comfortable and noninvasive, can solve this problem because the soft contact lens with an embedded micro fabricated strain gauge allows the measurement of changes in corneal curvature to correlate to variations of intraocular pressure. We fabricated a strain gauge using micro-electron mechanical systems, and integrated with the contact lens made of polydimethylsiloxane (PDMS) using injection molding. The experimental results showed that the sensitivity was 100. 7 µV/µm. When attached to the corneal surface, the average sensitivity of sensor response of intraocular pressure can be 125.8 µV/mm Hg under the ideal condition.
authors.forename: Xuhong
authors.initials: X
authors.lastname: Guo
authors.forename: Weihua
authors.initials: W
authors.lastname: Pet
authors.forename: Zhaolin
authors.initials: Z
authors.lastname: Yao
authors.forename: Yuanfang
authors.initials: Y
authors.lastname: Chen
authors.forename: Xiaohui
authors.initials: X
authors.lastname: Hu
authors.forename: Hongda
authors.initials: H
authors.lastname: Chen
authors.forename: Jingyuan
authors.initials: J
authors.lastname: Zhu
authors.forename: Huijuan
authors.initials: H
authors.lastname: Wu
mesh_terms: D003263:Contact Lenses, Hydrophilic; D004129:Dimethylpolysiloxanes; D005901:Glaucoma; D006801:Humans; D007429:Intraocular Pressure; D014065:Tonometry, Ocular / Q000295:instrumentation*
chemical_list: D004129:Dimethylpolysiloxanes; C013830:baysilon