title: Diagnosis of Alcoholic Liver Disease: Key Foundations and New Developments.
abstract: Alcoholic liver disease is a spectrum of conditions that include alcoholic fatty liver disease, alcoholic hepatitis, and chronic alcoholic liver disease. The diagnosis of alcoholic liver disease remains founded in an accurate patient history and detailed physical examination. Concurrent with the physical examination, objective data from laboratory, imaging, and histologic studies are helpful to confirm a diagnosis of alcoholic liver disease. Novel biomarkers, scoring systems, and imaging modalities are improving the ability to diagnose and manage alcoholic liver disease, but for most practicing clinicians, these have not been adopted widely because of their cost, but also because of limitations and uncertainty in their performance characteristics.
authors.affiliation: Division of Gastroenterology, Department of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Mailcode L-461, Portland, OR 97239, USA.
authors.forename: Ryan E
authors.initials: RE
authors.lastname: Childers
authors.affiliation: Division of Gastroenterology, Department of Medicine, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA. Electronic address: ahnj@ohsu.edu.
authors.forename: Joseph
authors.initials: J
authors.lastname: Ahn
mesh_terms: D015415:Biomarkers / Q000097:blood; D001706:Biopsy; D006801:Humans; D008099:Liver / Q000000981:diagnostic imaging / Q000201:enzymology; D008108:Liver Diseases, Alcoholic / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology; D008487:Medical History Taking; D012307:Risk Factors
chemical_list: D015415:Biomarkers
keywords: Alcoholic fatty liver disease; Alcoholic hepatitis; Alcoholic liver disease; Chronic alcoholic liver disease; Cirrhosis