title: Neurofilament Light: A Dynamic Cross-Disease Fluid Biomarker for Neurodegeneration.
abstract: In the current issue of Neuron, Bacioglu, Maia, and colleagues show that neurofilament light concentrations in body fluids reflect pathology and symptoms in mouse models of cerebral proteopathies and that these findings translate to human disease (Bacioglu et al., 2016).
authors.affiliation: Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, 40530 Göteborg, Sweden; Clinical Neurochemistry Laboratory, Sahlgrenska University Hospital, 41345 Göteborg, Sweden; Department of Molecular Neuroscience, UCL Institute of Neurology, Queen Square, London WC1N 3BG, UK. Electronic address: henrik.zetterberg@clinchem.gu.se.
authors.forename: Henrik
authors.initials: H
authors.lastname: Zetterberg
mesh_terms: D000818:Animals; D001369:Axons / Q000378:metabolism*; D015415:Biomarkers / Q000134:cerebrospinal fluid / Q000378:metabolism*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D006801:Humans; D007382:Intermediate Filaments / Q000378:metabolism*; D016900:Neurofilament Proteins / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*
chemical_list: D015415:Biomarkers; D016900:Neurofilament Proteins