title: [Recent advances of miRNAs in adipose tissues].
abstract: microRNAs (miRNAs), a class of endogenous non-coding RNA about 22 nucleotide long, regulate gene expression at the post-transcription level by inhibiting the translation or inducing the degradation of their target mRNAs in organisms. A lot of studies reveal that miRNAs in adipose tissues are involved in adipocyte differentiation and lipid metabolism and modulated by multiple transcription factors, adipocytokines and environmental factors, which form a complex regulatory network maintaining the homeostasis of adipose tissues. The discovery of circulating miRNAs adds new elements to the regulatory network. To study the metabolic diseases such as obesity, we should keep a new insight into the complex dynamic network. In this review, we summarize the latest studies of miRNAs in adipose tissues, which might provide new strategies for the treatment of obesity and other related diseases.
authors.forename: Yuntao
authors.initials: Y
authors.lastname: Guo
authors.forename: Xiuxiu
authors.initials: X
authors.lastname: Zhang
authors.forename: Wanlong
authors.initials: W
authors.lastname: Huang
authors.forename: Xiangyang
authors.initials: X
authors.lastname: Miao
mesh_terms: D054392:Adipokines / Q000378:metabolism; D000273:Adipose Tissue / Q000378:metabolism*; D002454:Cell Differentiation; D005786:Gene Expression Regulation; D006801:Humans; D050356:Lipid Metabolism; D035683:MicroRNAs / Q000378:metabolism*; D009765:Obesity / Q000378:metabolism; D012333:RNA, Messenger; D014157:Transcription Factors / Q000378:metabolism
chemical_list: D054392:Adipokines; D035683:MicroRNAs; D012333:RNA, Messenger; D014157:Transcription Factors