title: Current insights into the impact of dihydropyrimidine dehydrogenase deficiency in patients receiving treatment with 5-fluorouracil.
authors.affiliation: Mayo Clinic Cancer Center, College of Medicine, Rochester, Minnesota.
authors.forename: Robert B
authors.initials: RB
authors.lastname: Diasio
mesh_terms: D000964:Antimetabolites, Antineoplastic / Q000494:pharmacology / Q000627:therapeutic use*; D054067:Dihydropyrimidine Dehydrogenase Deficiency / Q000150:complications*; D042943:Dihydrouracil Dehydrogenase (NADP) / Q000235:genetics; D005472:Fluorouracil / Q000494:pharmacology / Q000627:therapeutic use*; D014644:Genetic Variation; D006801:Humans; D009369:Neoplasms / Q000150:complications* / Q000188:drug therapy*; D010597:Pharmacogenetics; D000071184:Pharmacogenomic Variants; D012106:Research; D016896:Treatment Outcome
chemical_list: D000964:Antimetabolites, Antineoplastic; D042943:Dihydrouracil Dehydrogenase (NADP); D005472:Fluorouracil