title: Review of the clinical significance of respiratory virus infections in newborn infants.
abstract: Respiratory viruses have been recognised as causative agents for a wide spectrum of clinical manifestations and severe respiratory compromise in neonates during birth hospitalisation. Early-life respiratory virus infections have also been shown to be associated with adverse long-term consequences.
  
  
  CONCLUSIONS
  Preventing virus infections by intensifying hygiene measures and cohorting infected infants should be a major goal for neonatal intensive care units, as well as more common use of virus diagnostics. Active virus surveillance and long-term follow-up are needed to ascertain the causality and exact underlying mechanisms for adverse long-term consequences.
authors.affiliation: Department of Paediatrics and Adolescent Medicine, University of Turku and Turku University Hospital, Turku, Finland. raakel.luoto@utu.fi.
authors.forename: Raakel
authors.initials: R
authors.lastname: Luoto
authors.affiliation: Department of Paediatrics and Adolescent Medicine, University of Turku and Turku University Hospital, Turku, Finland.
authors.forename: Tuomas
authors.initials: T
authors.lastname: Jartti
authors.affiliation: Department of Paediatrics and Adolescent Medicine, University of Turku and Turku University Hospital, Turku, Finland.
authors.forename: Olli
authors.initials: O
authors.lastname: Ruuskanen
authors.affiliation: Department of Virology, University of Turku, Turku, Finland.
authors.forename: Matti
authors.initials: M
authors.lastname: Waris
authors.affiliation: Department of Paediatrics and Adolescent Medicine, University of Turku and Turku University Hospital, Turku, Finland.
authors.forename: Liisa
authors.initials: L
authors.lastname: Lehtonen
authors.affiliation: Department of Paediatrics and Adolescent Medicine, University of Turku and Turku University Hospital, Turku, Finland.
authors.forename: Terho
authors.initials: T
authors.lastname: Heikkinen
mesh_terms: D006801:Humans; D007231:Infant, Newborn; D012141:Respiratory Tract Infections / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*; D014777:Virus Diseases / Q000175:diagnosis / Q000209:etiology / Q000628:therapy*
keywords: Acute respiratory tract infection; Infant; Infection; Newborn; Respiratory virus