title: Deriving the reference value from the circadian motor active patterns in the "non-dementia" population, compared to the "dementia" population: What is the amount of physical activity conducive to the good circadian rhythm.
abstract: The circadian rhythm in older adults is commonly known to change with a decrease in physical activity. However, the association between circadian rhythm metrics and physical activity remains unclear. The objective of this study was to examine circadian activity patterns in older people with and without dementia and to determine the amount of physical activity conducive to a good circadian measurement.
  
  
  
  Circadian parameters were collected from 117 older community-dwelling people (66 subjects without dementia and 52 subjects with dementia); the parameters were measured continuously using actigraphy for 7 days. A receiver operating characteristic (ROC) curve was applied to determine reference values for the circadian rhythm parameters, consisting of interdaily stability (IS), intradaily variability (IV), and relative amplitude (RA), in older subjects.
  
  
  
  The ROC curve revealed reference values of 0.55 for IS, 1.10 for IV, and 0.82 for RA. In addition, as a result of the ROC curve in the moderate-to-vigorous physical Activity (MVPA) conducive to the reference value of the Non-parametric Circadian Rhythm Analysis per day, the optimal reference values were 51 minutes for IV and 55 minutes for RA. However, the IS had no classification accuracy.
  
  
  
  Our results demonstrated the reference values derived from the circadian parameters of older Japanese population with or without dementia. Also, we determined the MVPA conducive to a good circadian rest-active pattern. This reference value for physical activity conducive to a good circadian rhythm might be useful for developing a new index for health promotion in the older community-dwelling population.
authors.affiliation: a Doctor Course , Graduate School of Health Sciences, Akita University , Hondo Akitaken , Japan.
authors.forename: Ayuto
authors.initials: A
authors.lastname: Kodama
authors.affiliation: b Department of Occupational Therapy , Graduate School of Health Sciences, Akita University , Hondo Akitaken , Japan.
authors.forename: Yu
authors.initials: Y
authors.lastname: Kume
authors.affiliation: b Department of Occupational Therapy , Graduate School of Health Sciences, Akita University , Hondo Akitaken , Japan.
authors.forename: Megumi
authors.initials: M
authors.lastname: Tsugaruya
authors.affiliation: b Department of Occupational Therapy , Graduate School of Health Sciences, Akita University , Hondo Akitaken , Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Ishikawa
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002940:Circadian Rhythm / Q000502:physiology*; D003704:Dementia; D005260:Female; D006801:Humans; D008297:Male; D009043:Motor Activity / Q000502:physiology*
keywords: Actical; Actiwatch2; circadian rhythm; physical activity