title: Microchips in Medicine: Current and Future Applications.
abstract: With the objective of improving efficacy and morbidity, device manufacturers incorporate chemicals or drugs into medical implants. Using multiple reservoirs of discrete drug doses, microchips represent a new technology capable of on-demand release of various drugs over long periods of time. Herein, we review drug delivery systems, how microchips work, recent investigations, and future applications in various fields of medicine.
authors.affiliation: Brown University, Providence, RI 02903, USA.
authors.forename: Adam E M
authors.initials: AE
authors.lastname: Eltorai
authors.affiliation: Brown University, Providence, RI 02903, USA.
authors.forename: Henry
authors.initials: H
authors.lastname: Fox
authors.affiliation: Brown University, Providence, RI 02903, USA.
authors.forename: Emily
authors.initials: E
authors.lastname: McGurrin
authors.affiliation: Brown University, Providence, RI 02903, USA.
authors.forename: Stephanie
authors.initials: S
authors.lastname: Guang
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods*; D004343:Drug Implants / Q000627:therapeutic use*; D065546:Drug Liberation / Q000502:physiology; D006801:Humans; D056656:Lab-On-A-Chip Devices; D004364:Pharmaceutical Preparations / Q000008:administration & dosage* / Q000737:chemistry*
chemical_list: D004343:Drug Implants; D004364:Pharmaceutical Preparations