title: Structure-based discovery and development of natural products as Type II JAK2 inhibitors for the treatment of hepatitis C.
authors.affiliation: Department of Chemistry, Hong Kong Baptist University, Hong Kong.
authors.forename: E Dl
authors.initials: ED
authors.lastname: Ma
authors.forename: C H
authors.initials: CH
authors.lastname: Leung
authors.forename: P
authors.initials: P
authors.lastname: Chiu
authors.forename: Y C
authors.initials: YC
authors.lastname: Cheng
mesh_terms: D000998:Antiviral Agents / Q000737:chemistry / Q000494:pharmacology*; D001688:Biological Products / Q000737:chemistry / Q000494:pharmacology; D002460:Cell Line; D015195:Drug Design; D055808:Drug Discovery; D016174:Hepacivirus / Q000201:enzymology / Q000235:genetics; D006526:Hepatitis C / Q000188:drug therapy* / Q000201:enzymology / Q000821:virology; D006723:Hong Kong; D006801:Humans; D053614:Janus Kinase 2 / Q000037:antagonists & inhibitors*; D062105:Molecular Docking Simulation; D047428:Protein Kinase Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D013329:Structure-Activity Relationship
chemical_list: D000998:Antiviral Agents; D001688:Biological Products; D047428:Protein Kinase Inhibitors; C507924:JAK2 protein, human; D053614:Janus Kinase 2