title: Nonobstructive Acute Renal Failure with a Large Solitary Fibroid.
abstract: A 38-year-old African American woman presenting with acute abdominal pain and nonobstructive renal failure was found to have an enlarged fibroid uterus. A differential for sepsis was considered. Lab evaluation revealed an elevated creatinine and myoglobin level at 3.9 mg/dL and 2140 ng/mL, respectively. Ongoing hemodynamic instability mandated surgery for acute abdomen. A 25 cm fibroid uterus was extirpated through a total abdominal hysterectomy. Immediate improvement of acute nephropathy mirrored the postoperative decline in serum myoglobin levels. Myoglobinemia from a massive degenerating fibroid is associated with nonobstructive acute renal failure.
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee Chattanooga College of Medicine, Chattanooga, TN 37403, USA.
authors.forename: Rayan
authors.identifier: 0000-0003-3182-6203
authors.initials: R
authors.lastname: Elkattah
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee Chattanooga College of Medicine, Chattanooga, TN 37403, USA.
authors.forename: Zineb
authors.identifier: 0000-0002-4187-5765
authors.initials: Z
authors.lastname: Mashak
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee Chattanooga College of Medicine, Chattanooga, TN 37403, USA.
authors.forename: Blakele
authors.initials: B
authors.lastname: Bakker
authors.affiliation: Department of Obstetrics and Gynecology, University of Tennessee Chattanooga College of Medicine, Chattanooga, TN 37403, USA.
authors.forename: Shanti
authors.identifier: 0000-0003-3376-2629
authors.initials: S
authors.lastname: Mohling
authors.affiliation: Gülhane Military Medical Academy Haydarpasa Training Hospital, Department of Obstetrics and Gynecology, Selimiye Mahallesi, Tibbiye Caddesi, 34668 Istanbul, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Yilmaz
authors.affiliation: Division of Gynecology Oncology, University of Tennessee Chattanooga College of Medicine, Chattanooga, TN 37403, USA.
authors.forename: Stephen
authors.initials: S
authors.lastname: DePasquale
authors.affiliation: Division of Gynecology Oncology, University of Tennessee Chattanooga College of Medicine, Chattanooga, TN 37403, USA.
authors.forename: Todd
authors.initials: T
authors.lastname: Boren