title: Pragmatic use of insulin degludec/insulin aspart co-formulation: A multinational consensus statement.
abstract: Insulin degludec/insulin aspart (IDegAsp) is a modern coformulation of ultra-long-acting basal insulin degludec, with rapid-acting insulin aspart. IDegAsp provides effective, safe, well-tolerated glycemic control, with a low risk of hypoglycemia while allowing flexibility in meal patterns and timing of administration. This consensus statement describes a pragmatic framework to identify patients who may benefit from IDegAsp therapy. It highlights the utility of IDegAsp in type 2 diabetic patients who are insulin-naive, suboptimally controlled on basal or premixed insulin, or dissatisfied with basal-bolus regimens. It also describes potential IDegAsp usage in type 1 diabetic patients.
authors.affiliation: Department of Endocrinology, Bharti Hospital, Karnal, Haryana, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kalra
authors.affiliation: Director, Department of Endocrinology, BIRDEM, Dhaka, Bangladesh.
authors.forename: Zafar A
authors.initials: ZA
authors.lastname: Latif
authors.affiliation: Division of Endocrinology, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Comlekci
authors.affiliation: Department of Endocrinology, Instituto Jalisciense de Investigación en Diabetes y Obesidad, S.C, Mexico.
authors.forename: Guillermo Gonzalez
authors.initials: GG
authors.lastname: Galvez
authors.affiliation: Department of Medicine, Setif, Algeria.
authors.forename: Rached
authors.initials: R
authors.lastname: Malik
authors.affiliation: Department of Endocrinology, BIRDEM, Dhaka, Bangladesh.
authors.forename: Md Faruque
authors.initials: MF
authors.lastname: Pathan
authors.affiliation: Department of Medicine, Diabetes Centre, Patna, Bihar, India.
authors.forename: Ajay
authors.initials: A
authors.lastname: Kumar
keywords: Basal–bolus; basal insulin; coformulation; flexibility; hypoglycemia; insulin; insulin aspart; insulin degludec; insulin degludec/insulin aspart; premixed insulin