title: An Atypical Case of Mounier-Kuhn Syndrome: Time to Change the Diagnostic Approach?
abstract: Mounier-Kuhn syndrome (MKS) is a rare disease of unknown etiology characterized by abnormal pathologic dilatation of tracheabronchial tree. The diagnosis of MKS is normally made on CT scan of chest on the basis of enlarged diameters of trachea and main stem bronchi. We are presenting histologically confirmed case of MKS, where the diameter of right main bronchus is below minimum diameter (mean+3 SD) required for the diagnosis. We suggest that the diagnosis of MKS should not be solely based on fixed criteria such as the diameter of airways, but on the basis of the overall clinical, pathologic, and radiologic profile.
authors.affiliation: Department of Pulmonary Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, India.
authors.forename: Ashok
authors.initials: A
authors.lastname: Kuwal
authors.forename: Naveen
authors.initials: N
authors.lastname: Dutt
authors.forename: Nishant
authors.initials: N
authors.lastname: Chauhan
authors.forename: Sunil
authors.initials: S
authors.lastname: Kumar
authors.forename: Swetabh
authors.initials: S
authors.lastname: Purohit
authors.forename: Lokesh K
authors.initials: LK
authors.lastname: Saini
mesh_terms: D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001993:Bronchodilator Agents / Q000627:therapeutic use; D001999:Bronchoscopy / Q000379:methods*; D006801:Humans; D008297:Male; D008382:Marfan Syndrome / Q000150:complications*; D026741:Physical Therapy Modalities; D011018:Pneumonia, Pneumococcal / Q000175:diagnosis* / Q000188:drug therapy; D013296:Streptococcus pneumoniae / Q000302:isolation & purification; D014057:Tomography, X-Ray Computed / Q000379:methods; D014137:Tracheobronchomegaly / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000188:drug therapy
chemical_list: D000900:Anti-Bacterial Agents; D001993:Bronchodilator Agents