title: Association of blood neutrophil lymphocyte ratio in the patients with postmenopausal osteoporosis.
abstract: OBJECTIVE
  To investigate the relationship between blood neutrophil lymphocyte ratio (NLR) and postmenopausal osteoporosis in Chinese women without diabetes.
  
  
  METHODS
  Two hundred and thirty three postmenopausal women without diabetes were included in this study. The clinical data of patients including age, and body mass index (BMI) were recorded. Blood samples were obtained to determine Blood urea nitrogen (BUN), Uric acid (UA), Albumin (ALB), Creatinine (CREA), Total Cholesterol(TC), Triglyceride (TG), Fasting plasma glucose (FPG), Glycosylated Hemoglobin (HbAlc), 25-hydroxyitamin D (25-OHD) level. NLR was calculated using the following formulas: NLR = Neutrophil count / lymphocyte count; Bone mineral density (BMD) of the lumbar vertebrae and the femoral neck was measured. The relationship between NLR and postmenopausal osteoporosis statistical methods was analyzed.
  
  
  RESULTS
  Age, BMD, Albumin (ALB), Creatinine(CREA), Triglyceride (TG) and NLR level were different in the three groups (P<0.05). Logistic regression analysis showed that the age and NLR level were risk factors for postmenopausal osteoporosis.
  
  
  CONCLUSIONS
  NLR level was strongly associated with BMD in the postmenopausal women without diabetes, suggesting that NLR could become a helpful clinical tool in the assessment of postmenopausal osteoporosis.
authors.affiliation: Dr. Chenshu Huang, PhD, MD. Department of Radiation Medicine and Tumor, College of Basic Medicine, Chongqing Medical University, Yuzhong District, Chongqing, China.
authors.forename: Chenshu
authors.initials: C
authors.lastname: Huang
authors.affiliation: Prof. Shaolin Li, Department of Radiation Medicine and Tumor, College of Basic Medicine, Chongqing Medical University, Yuzhong District, Chongqing, China.
authors.forename: Shaolin
authors.initials: S
authors.lastname: Li
keywords: Bone mineral density; Neutrophil lymphocyte ratio; Osteoporosis; Postmenopausal