title: Modeling Zika Virus Infection in Mice.
abstract: Understanding the link between Zika virus (ZIKV) infection and microcephaly requires in vivo models of ZIKV infection in pregnant adults and fetuses. Three studies recently generated such mouse models of ZIKV infection, which corroborate previous in vitro evidence linking ZIKV infection and apoptosis induction in neurons and progenitors to microcephaly.
authors.affiliation: Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555-0609, USA. Electronic address: slrossi@utmb.edu.
authors.forename: Shannan L
authors.initials: SL
authors.lastname: Rossi
authors.affiliation: Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA; Center for Biodefense and Emerging Infectious Diseases, University of Texas Medical Branch, Galveston, TX 77555-0609, USA; Center for Tropical Diseases, University of Texas Medical Branch, Galveston, TX 77555-0609, USA; Institute for Human Infections and Immunity, University of Texas Medical Branch, Galveston, TX 77555-0609, USA. Electronic address: nivasila@utmb.edu.
authors.forename: Nikos
authors.initials: N
authors.lastname: Vasilakis
mesh_terms: D000818:Animals; D017209:Apoptosis; D005260:Female; D005333:Fetus; D051379:Mice; D009474:Neurons; D011247:Pregnancy; D000071244:Zika Virus; D000071243:Zika Virus Infection