title: Giant Onychomatricoma of the Great Toenail: Case Report and Review Focusing on Less Common Variants.
abstract: Onychomatricoma is a rare benign fibroepithelial filamentous tumor originating from the nail matrix. It typically presents with the clinical tetrad of xanthonychia, pachyonychia, proximal splinter hemorrhages and increased transverse overcurvature of the nail plate. The giant variant can easily confuse the clinician due to its extensive nail dystrophy that can mask the characteristic features of this tumor. Benign (fibrokeratoma, ungual fibroma, onycholytic matricoma) and malignant entities (Bowen's disease, squamous cell carcinoma, onycholytic carcinoma) are mimics of the disease. Nail surgery can facilitate the diagnosis, which should always be confirmed by histology, as rare variants do exist.
authors.affiliation: Nail Disorders Unit, Second Department of Dermatology, Attikon University Hospital, Athens, Greece.
authors.forename: Christos
authors.initials: C
authors.lastname: Prevezas
authors.affiliation: Nail Disorders Unit, Second Department of Dermatology, Attikon University Hospital, Athens, Greece.
authors.forename: Ioanna
authors.initials: I
authors.lastname: Triantafyllopoulou
authors.affiliation: Nail Disorders Unit, Second Department of Dermatology, Attikon University Hospital, Athens, Greece.
authors.forename: Helena
authors.initials: H
authors.lastname: Belyayeva
authors.affiliation: Nail Disorders Unit, Second Department of Dermatology, Attikon University Hospital, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Sgouros
authors.affiliation: Second Department of Pathology, Attikon University Hospital, Athens, Greece.
authors.forename: Stephanos
authors.initials: S
authors.lastname: Konstantoudakis
authors.affiliation: Second Department of Pathology, Attikon University Hospital, Athens, Greece.
authors.forename: Ioannis
authors.initials: I
authors.lastname: Panayiotides
authors.affiliation: Nail Disorders Unit, Second Department of Dermatology, Attikon University Hospital, Athens, Greece.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Rigopoulos
keywords: Giant; Nail tumor; Onychomatricoma; Uncommon type