title: A case of giant cell tumor of soft parts in a horse.
abstract: A 12-year-old British Warmblood mare was examined by the referring veterinarian for evaluation of a cutaneous lesion on the dorsal thorax to the right of the midline. Cytologic examination of fine-needle aspirates from the mass was supportive of a giant cell tumor of soft parts (GCTSP). Laser surgical excision and postoperative methyl aminolevulinate (MAL) photodynamic therapy (PDT) were performed. Histologic examination of the mass confirmed the cytologic diagnosis. At 8 months from surgery, no evidence of recurrence has been observed. Giant cell tumors of soft parts are rare cutaneous neoplasms, observed in several domestic species, including the horse where they commonly appear as superficial cutaneous lesions without aggressive biologic behavior. Previously classified as giant cell variant of malignant fibrous histiocytoma, these superficial tumors have now been designated as giant cell tumors of soft tissue or giant cell tumors of low malignant potential within the category of fibrohistiocytic neoplasms.
authors.affiliation: Animal Health Trust, Newmarket, UK. francesco.cian@hotmail.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Cian
authors.affiliation: 608 Equine and Farm Vets, Rowington, UK.
authors.forename: Sarah
authors.initials: S
authors.lastname: Whiteoak
authors.affiliation: Animal Health Trust, Newmarket, UK.
authors.forename: Jennifer
authors.identifier: http://orcid.org/0000-0002-9707-3235
authors.initials: J
authors.lastname: Stewart
mesh_terms: D000818:Animals; D044963:Biopsy, Fine-Needle; D005260:Female; D005870:Giant Cell Tumors / Q000662:veterinary*; D006734:Horse Diseases / Q000175:diagnosis*; D006736:Horses; D012878:Skin Neoplasms / Q000662:veterinary*; D013909:Thorax / Q000473:pathology
keywords: Cytology; equine; giant cell tumor