title: Central Body Fat Mass Measured by Bioelectrical Impedanciometry But Not Body Mass Index Is a High-Grade Prostate Cancer Risk Factor.
abstract: OBJECTIVE
  To evaluate the association between body fat mass distribution measured by bioelectrical impedanciometry (BEI) and high-grade prostate cancer (HGPC).
  
  
  METHODS
  We prospectively analyze 323 patients who underwent prostate biopsy. BEI was performed prior to biopsy. Prostate cancer (PC) was stratified according to D'Amico classification. For univariate analysis, Student t test was done. For multivariate analysis, bivariate logistic regression was performed using PSA, body mass index (BMI), percentage central body fat, percentage total body fat, and visceral fat as explicative variables for the diagnosis of HGPC.
  
  
  RESULTS
  PC was found in 134 patients. Thirty seven (27.2%) were HGPC. This group had higher age, PSA, and percentage central body fat (p = 0.001, p = 0.001, p = 0.04). BMI showed no association with HRPC. Age, PSA, and percentage central body fat (OR 1,123, 95% CI 1,022-1,233, p = 0.001) were independent risk factors.
  
  
  CONCLUSIONS
  Central body fat measured by BEI could explain the association between obesity and HGPC better than BMI suggesting the use of this technique to study body fat distribution.
authors.affiliation: Department of Urology, Universitary and Politecnic Hospital La Fe, Valencia, Spain.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Morán Pascual
authors.forename: Manuel
authors.initials: M
authors.lastname: Martínez Sarmiento
authors.forename: Alberto
authors.initials: A
authors.lastname: Budía Alba
authors.forename: Enrique
authors.initials: E
authors.lastname: Broseta Rico
authors.forename: Rosa
authors.initials: R
authors.lastname: Cámara Gómez
authors.forename: Francisco
authors.initials: F
authors.lastname: Boronat Tormo
mesh_terms: D000368:Aged; D001706:Biopsy; D050218:Body Fat Distribution; D015992:Body Mass Index; D017097:Electric Impedance; D006801:Humans; D008297:Male; D008875:Middle Aged; D060787:Neoplasm Grading; D011446:Prospective Studies; D011471:Prostatic Neoplasms / Q000453:epidemiology* / Q000473:pathology*; D012307:Risk Factors