title: Patient-reported outcomes 5 years after laser in situ keratomileusis.
abstract: To assess vision-related, quality-of-life outcomes 5 years after laser in situ keratomileusis (LASIK) and determine factors predictive of patient satisfaction.
  
  
  
  Optical Express, Glasgow, Scotland.
  
  
  
  Retrospective case series.
  
  
  
  Data from patients who had attended a clinical examination 5 years after LASIK were analyzed. All treatments were performed using the Visx Star S4 IR excimer laser. Patient-reported satisfaction, the effect of eyesight on various activities, visual phenomena, and ocular discomfort were evaluated 5 years postoperatively. Multivariate regression analysis was performed to determine factors affecting patient satisfaction.
  
  
  
  The study comprised 2530 patients (4937 eyes) who had LASIK. The mean age at the time of surgery was 42.4 years ± 12.5 (SD), and the preoperative manifest spherical equivalent ranged from -11.0 diopters (D) to +4.88 D. Five years postoperatively, 79.3% of eyes were within ±0.50 D of emmetropia and 77.7% of eyes achieved monocular uncorrected distance visual acuity (UDVA) and 90.6% of eyes achieved binocular UDVA of 20/20 or better. Of the patients, 91.0% said they were satisfied with their vision and 94.9% did not wear distance correction. Less than 2.0% of patients noticed visual phenomena, even with spectacle correction. Major predictors of patient satisfaction 5 years postoperatively were postoperative binocular UDVA (37.6% variance explained by regression model), visual phenomena (relative contribution of 15.0%), preoperative and postoperative sphere and their interactions (11.6%), and eyesight-related difficulties with various activities such as night driving, outdoor activities, and reading (10.2%).
  
  
  
  Patient-reported quality-of-life and satisfaction rates remained high 5 years after LASIK. Uncorrected vision was the strongest predictor of satisfaction.
  
  
  
  Dr. S.C. Schallhorn is a consultant to Abbott Medical Optics, Inc., Zeiss Meditec AG, and Autofocus Inc. and a global medical director for Optical Express. No other author has a financial or proprietary interest in any material or method mentioned.
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland. Electronic address: scschallhorn@yahoo.com.
authors.forename: Steven C
authors.initials: SC
authors.lastname: Schallhorn
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland.
authors.forename: Jan A
authors.initials: JA
authors.lastname: Venter
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland.
authors.forename: David
authors.initials: D
authors.lastname: Teenan
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland.
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: Hannan
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland.
authors.forename: Keith A
authors.initials: KA
authors.lastname: Hettinger
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland.
authors.forename: Martina
authors.initials: M
authors.lastname: Pelouskova
authors.affiliation: From the Departments of Ophthalmology, University of California (S.C. Schallhorn), San Francisco, and University of Southern California (S.C. Schallhorn, J.M. Schallhorn), Los Angeles, California, USA; Optical Express (S.C. Schallhorn, Venter, Teenan, Hannan, Hettinger, Pelouskova), Glasgow, Scotland.
authors.forename: Julie M
authors.initials: JM
authors.lastname: Schallhorn
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D020731:Keratomileusis, Laser In Situ; D054018:Lasers, Excimer; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000628:therapy*; D000071066:Patient Reported Outcome Measures; D012029:Refraction, Ocular; D012189:Retrospective Studies; D016896:Treatment Outcome