title: A very unusual cause of dysphagia: mantle cell lymphoma.
abstract: Dysphagia is an alarm symptom requiring a prompt investigation. Different benign and malignant diseases may present such a symptom. We describe a case of a 79-year-old patient who complained of fluctuating dysphagia episodes following solid food ingestion in the previous 5 months with mild weight loss. No other gastrointestinal symptoms were present. The patient was referred by the General Practitioner for a videofluoroscopic swallow examination which revealed nodularity of mucosa surface in the oropharynx, esophagus, fundus, and gastric body. Upper endoscopy confirmed the feature, also showing a normal mucosa of the antrum and duodenum. The histological examination revealed a mantle cell lymphoma (MCL). A stage III, MCL involving the esophagus and proximal stomach was eventually diagnosed. Esophageal MCL localization is extremely rare, and this is the first report showing a clinical onset with dysphagia.
authors.affiliation: Department of Gastronterology (Angelo Zullo, Vincenzo Bruzzese), Rome, Italy.
authors.forename: Angelo
authors.initials: A
authors.lastname: Zullo
authors.affiliation: Department of Radiology (Paola Cerro, Anastassios Chios), Rome, Italy.
authors.forename: Paola
authors.initials: P
authors.lastname: Cerro
authors.affiliation: Department of Radiology (Paola Cerro, Anastassios Chios), Rome, Italy.
authors.forename: Anastassios
authors.initials: A
authors.lastname: Chios
authors.affiliation: Department of Haematology (Alessandro Andriani), Nuovo Regina Margherita Hospital, Rome, Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Andriani
authors.affiliation: Department of Pathology, Santo Spirito Hospital, Rome (Giuseppina Balsamo), Italy.
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Balsamo
authors.affiliation: Department of Gastronterology, Riuniti Hospital, Foggia (Vincenzo De Francesco), Italy.
authors.forename: Vincenzo De
authors.initials: VD
authors.lastname: Francesco
authors.affiliation: Department of Gastronterology (Angelo Zullo, Vincenzo Bruzzese), Rome, Italy.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Bruzzese
keywords: Mantle cell lymphoma; dysphagia; endoscopy; esophagus; stomach