title: Primary squamous cell carcinoma of the breast: a case report and review of literature.
abstract: Primary squamous cell carcinoma is a well known malignancy of the skin and other organs composed of squamous cells, which are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceedingly uncommon phenomen and the management of this type of disease is still unclear. We report the case of a 43-year-old Moroccan woman, without significant medical history, presented an infected mass of 9 cm in the left breast associated with ipsilateral axillary lymphadenopathy. The mass's surgical biopsy revealed a triple negative primary squamous cell carcinoma of the breast. She underwent a neoadjuvant chemotherapy using 5 Fluoro-Uracil and platinum. After three courses, she presented a contralateral breast progression and apparition of metastasis at D10. She received one course of a palliative chemotherapy based on weekly paclitaxel stopped because of her peformans status deterioration. She died 7 months after her admission.
authors.affiliation: Medical Oncology Department, University Hospital Mohammed VI, Oujda, Morocco.
authors.forename: Youssef
authors.initials: Y
authors.lastname: Seddik
authors.affiliation: Medical Oncology Department, University Hospital Mohammed VI, Oujda, Morocco.
authors.forename: Sami Aziz
authors.initials: SA
authors.lastname: Brahmi
authors.affiliation: Medical Oncology Department, University Hospital Mohammed VI, Oujda, Morocco.
authors.forename: Said
authors.initials: S
authors.lastname: Afqir
mesh_terms: D000328:Adult; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000008:administration & dosage*; D001706:Biopsy; D001943:Breast Neoplasms / Q000473:pathology* / Q000628:therapy; D002294:Carcinoma, Squamous Cell / Q000473:pathology* / Q000628:therapy; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D000072281:Lymphadenopathy / Q000473:pathology*; D020360:Neoadjuvant Therapy / Q000379:methods; D010166:Palliative Care / Q000379:methods
keywords: Primary squamous cell carcinoma; aggressive tumor; breast cancer