title: Acylated Triterpene Saponins from the Stem Bark of Acer nikoense (Aceraceae).
abstract: Three new acylated triterpene saponins, acernikoenosides A-C (1-3), were isolated from the stem bark of Acer nikoense, together with a known sterol glucoside. Their structures were elucidated on the basis of extensive spectroscopic analyses. This study provided the first example of triterpene saponins isolated from this plant. The anti-genotoxic activity of 1, 3 and 4 against ultraviolet irradiation was evaluated by comet assay.
authors.affiliation: Faculty of Pharmaceutical Sciences, Himeji Dokkyo University.
authors.forename: Shin-Ichiro
authors.initials: S
authors.lastname: Kurimoto
authors.forename: Yu F
authors.initials: YF
authors.lastname: Sasaki
authors.forename: Yoshihiro
authors.initials: Y
authors.lastname: Suyama
authors.forename: Naonobu
authors.initials: N
authors.lastname: Tanaka
authors.forename: Yoshiki
authors.initials: Y
authors.lastname: Kashiwada
authors.forename: Takanori
authors.initials: T
authors.lastname: Nakamura
mesh_terms: D031001:Aceraceae / Q000737:chemistry*; D000215:Acylation; D016587:Antimutagenic Agents / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D002478:Cells, Cultured; D006801:Humans; D015394:Molecular Structure; D024301:Plant Bark / Q000737:chemistry*; D018547:Plant Stems / Q000737:chemistry*; D012503:Saponins / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014315:Triterpenes / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology*; D014466:Ultraviolet Rays
chemical_list: D016587:Antimutagenic Agents; D012503:Saponins; D014315:Triterpenes; C000613663:acernikoenoside A; C000613664:acernikoenoside B; C000613665:acernikoenoside C