title: Autophagy modulators regulate survival motor neuron protein stability in motoneurons.
authors.affiliation: Unitat de Senyalització Neuronal, Dep. Medicina Experimental, Universitat de Lleida-IRBLLEIDA, Rovira Roure 80, 25198 Lleida, Spain.
authors.forename: Ambika
authors.initials: A
authors.lastname: Periyakaruppiah
authors.affiliation: Unitat de Senyalització Neuronal, Dep. Medicina Experimental, Universitat de Lleida-IRBLLEIDA, Rovira Roure 80, 25198 Lleida, Spain.
authors.forename: Sandra
authors.initials: S
authors.lastname: de la Fuente
authors.affiliation: Unitat de Senyalització Neuronal, Dep. Medicina Experimental, Universitat de Lleida-IRBLLEIDA, Rovira Roure 80, 25198 Lleida, Spain.
authors.forename: Saravanan
authors.initials: S
authors.lastname: Arumugam
authors.affiliation: Unitat de Senyalització Neuronal, Dep. Medicina Experimental, Universitat de Lleida-IRBLLEIDA, Rovira Roure 80, 25198 Lleida, Spain.
authors.forename: Núria
authors.initials: N
authors.lastname: Bahí
authors.affiliation: Unitat de Senyalització Neuronal, Dep. Medicina Experimental, Universitat de Lleida-IRBLLEIDA, Rovira Roure 80, 25198 Lleida, Spain.
authors.forename: Ana
authors.initials: A
authors.lastname: Garcera
authors.affiliation: Unitat de Senyalització Neuronal, Dep. Medicina Experimental, Universitat de Lleida-IRBLLEIDA, Rovira Roure 80, 25198 Lleida, Spain. Electronic address: rosa.soler@cmb.udl.cat.
authors.forename: Rosa M
authors.initials: RM
authors.lastname: Soler
mesh_terms: D000818:Animals; D000831:Animals, Newborn; D001343:Autophagy / Q000187:drug effects / Q000235:genetics / Q000502:physiology*; D002470:Cell Survival / Q000235:genetics / Q000502:physiology; D002478:Cells, Cultured; D004195:Disease Models, Animal; D004622:Embryo, Mammalian; D004791:Enzyme Inhibitors / Q000494:pharmacology; D018507:Gene Expression Regulation, Developmental / Q000187:drug effects / Q000235:genetics / Q000502:physiology; D018942:Macrolides / Q000494:pharmacology; D051379:Mice; D008822:Mice, Transgenic; D009046:Motor Neurons / Q000187:drug effects / Q000378:metabolism* / Q000648:ultrastructure; D009134:Muscular Atrophy, Spinal / Q000235:genetics / Q000473:pathology*; D009414:Nerve Growth Factors / Q000494:pharmacology; D009419:Nerve Tissue Proteins / Q000235:genetics / Q000378:metabolism*; D000071456:Sequestosome-1 Protein / Q000378:metabolism; D013116:Spinal Cord / Q000166:cytology / Q000254:growth & development; D055533:Survival of Motor Neuron 1 Protein / Q000235:genetics / Q000378:metabolism; D055540:Survival of Motor Neuron 2 Protein / Q000235:genetics / Q000378:metabolism
chemical_list: D004791:Enzyme Inhibitors; D018942:Macrolides; D009414:Nerve Growth Factors; D009419:Nerve Tissue Proteins; C526477:SMN2 protein, human; C099718:SQSTM1 protein, human; D000071456:Sequestosome-1 Protein; C526472:Smn1 protein, mouse; D055533:Survival of Motor Neuron 1 Protein; D055540:Survival of Motor Neuron 2 Protein; C040929:bafilomycin A1
keywords: Autophagosome; Autophagy; Calpain; Motoneuron; Rapamycin; Spinal Muscular Atrophy; Survival motor neuron