title: Refractive Regression and Changes in Central Corneal Thickness Three Years after Laser-Assisted Subepithelial Keratectomy for High Myopia in Eyes with Thin Corneas: A Retrospective Study.
abstract: This retrospective study aimed to explore refractive regression and central corneal thickness (CCT) following laser-assisted subepithelial keratectomy (LASEK) performed for the correction of high myopia in eyes with thin corneas. Forty patients (19 male, 21 female; mean age, 28.5 years) representing 76 treated eyes were included. The mean optical zone was 6.10 ± 0.32 mm, and the mean ablation depth was 121.53 ± 15.48 µm. CCT was significantly greater three years after surgery than at three months after surgery (425.66 ± 15.44 vs. 385.20 ± 12.81, respectively; p<0.001). The mean change in CCT from three months to three years was 40.46 ± 14.02 µm. The SE at three years was greater than that at three months (p<0.001). Although there was refractive regression, these data suggest that LASEK may have utility in the correction of high myopia in eyes with thin corneas.
authors.affiliation: a Department of Ophthalmology, Eye and ENT Hospital , Fudan University , Shanghai , PR China.
authors.forename: Dan
authors.initials: D
authors.lastname: Fu
authors.affiliation: b Department of Ophthalmology , Shanghai University of Traditional Chinese Medicine , Shanghai , PR China.
authors.forename: Zhen-Yong
authors.initials: ZY
authors.lastname: Zhang
authors.affiliation: a Department of Ophthalmology, Eye and ENT Hospital , Fudan University , Shanghai , PR China.
authors.forename: Lin
authors.initials: L
authors.lastname: Wang
authors.affiliation: a Department of Ophthalmology, Eye and ENT Hospital , Fudan University , Shanghai , PR China.|c Key Laboratory of Myopia , Ministry of Health , Shanghai , PR China.
authors.forename: Xing-Tao
authors.initials: XT
authors.lastname: Zhou
authors.affiliation: a Department of Ophthalmology, Eye and ENT Hospital , Fudan University , Shanghai , PR China.|c Key Laboratory of Myopia , Ministry of Health , Shanghai , PR China.
authors.forename: Zhi-Qiang
authors.initials: ZQ
authors.lastname: Yu
mesh_terms: D000293:Adolescent; D000328:Adult; D003315:Cornea / Q000473:pathology* / Q000601:surgery; D005260:Female; D006801:Humans; D049008:Keratectomy, Subepithelial, Laser-Assisted / Q000379:methods*; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery; D012029:Refraction, Ocular / Q000502:physiology*; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
keywords: Central corneal thickness; LASEK; PRK; cornea; myopia; refractive regression