title: Discrimination of Citrus reticulata Blanco and Citrus reticulata 'Chachi' by gas chromatograph-mass spectrometry based metabolomics approach.
abstract: Citri Reticulatae Pericarpium, mainly including the pericarp of Citrus reticulata Blanco and the pericarp of Citrus reticulata 'Chachi', has been consumed daily as food and dietary supplement for centuries. In this study, GC-MS based metabolomics was employed to compare comprehensively the volatile constituents in Citrus reticulata Blanco and Citrus reticulata 'Chachi'. Principal component analysis and orthogonal partial least squares discrimination analysis indicated that samples could be distinguished effectively from one another. Fifteen metabolites were finally identified for use as chemical markers in discrimination of Citri Reticulatae Pericarpium samples. The antimicrobial activity against Gram-negative and Gram-positive bacteria of the volatile oil from Citrus reticulata Blanco and Citrus reticulata 'Chachi' was investigated preliminarily.
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China.
authors.forename: Li
authors.initials: L
authors.lastname: Duan
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China.
authors.forename: Long
authors.initials: L
authors.lastname: Guo
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China.
authors.forename: Li-Li
authors.initials: LL
authors.lastname: Dou
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China.
authors.forename: Chang-Lin
authors.initials: CL
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China.
authors.forename: Feng-Guo
authors.initials: FG
authors.lastname: Xu
authors.affiliation: Department of Pharmacy, School of Pharmaceutical Sciences, Guangzhou Medical University, Guangzhou, PR China.
authors.forename: Guo-Dong
authors.initials: GD
authors.lastname: Zheng
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China. Electronic address: liping2004@126.com.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.affiliation: State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, PR China. Electronic address: liuehu2011@163.com.
authors.forename: E-Hu
authors.initials: EH
authors.lastname: Liu
mesh_terms: D002957:Citrus / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D055432:Metabolomics; D009822:Oils, Volatile / Q000032:analysis*
chemical_list: D009822:Oils, Volatile
keywords: Antimicrobial activity; Citri Reticulatae Pericarpium; Gas chromatography mass spectrometry; Metabolomics