title: Early detection of Zika virus infection among travellers from areas of ongoing transmission in China.
abstract: Nine imported Zika virus (ZIKV) infections (four through temperature monitoring and epidemiological investigation at entry and five by active surveillance tracking of index case contacts during follow-up; from Venezuela [n = 5], Samoa [n = 3] and both Samoa and Fiji [n = 1]) were detected in mainland China from February 1 to 29, 2016. The minimal incubation period lasted 5.2 days, with mean lag time to diagnosis of 2.6 days. Diagnosis relied on positive real-time reverse transcriptase polymerase chain reaction for ZIKV RNA in serum (n = 7), urine (n = 4) or saliva (n = 3), respectively. All cases recovered rapidly without serious complications.
authors.affiliation: General Administration of Quality Supervision, Inspection and Quarantine of PRC, Beijing, People's Republic of China.
authors.forename: Jiwen
authors.initials: J
authors.lastname: Zhang
authors.affiliation: General Administration of Quality Supervision, Inspection and Quarantine of PRC, Beijing, People's Republic of China.
authors.forename: Xia
authors.initials: X
authors.lastname: Jin
authors.affiliation: General Administration of Quality Supervision, Inspection and Quarantine of PRC, Beijing, People's Republic of China.
authors.forename: Zhaoyin
authors.initials: Z
authors.lastname: Zhu
authors.affiliation: Guangdong Entry and Exit Inspection and Quarantine Bureau, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Li
authors.initials: L
authors.lastname: Huang
authors.affiliation: Guangdong International Travel Health Care Center, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Shaojun
authors.initials: S
authors.lastname: Liang
authors.affiliation: Shenzhen International Travel Health Care Center, Shenzhen, Guangdong, People's Republic of China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Xu
authors.affiliation: Guangzhou Entry and Exit Inspection and Quarantine Bureau, Guangzhou, Guangdong, People's Republic of China.
authors.forename: Ruyan
authors.initials: R
authors.lastname: Liao
authors.affiliation: Shenzhen Entry-Exit Inspection and Quarantine Bureau, Shenzhen, Guangdong, People's Republic of China.
authors.forename: Licheng
authors.initials: L
authors.lastname: Zhou
authors.affiliation: Zhejiang Entry and Exit Inspection and Quarantine Bureau, Hangzhou, Zhejiang, People's Republic of China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.
authors.forename: Annelies
authors.initials: A
authors.lastname: Wilder-Smith
mesh_terms: D001769:Blood / Q000821:virology*; D002681:China; D005367:Fiji; D006801:Humans; D012367:RNA, Viral / Q000097:blood*; D060888:Real-Time Polymerase Chain Reaction / Q000379:methods; D018947:Samoa; D014195:Travel; D014556:Urine / Q000821:virology*; D014687:Venezuela; D000071244:Zika Virus / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000175:diagnosis* / Q000821:virology
chemical_list: D012367:RNA, Viral
keywords: Zika virus; detection; imported case