title: 2014 Jeffrey M. Hoeg Award Lecture: Transcriptional Control of Monocyte Development.
abstract: Monocytes and macrophages are key immune cells involved in the early progression of atherosclerosis. Transcription factors that control their development in the bone marrow are important therapeutic targets to control the numbers and functions of these cells in disease. This review highlights what is currently known about the transcription factors that are critical for monocyte development.
authors.affiliation: From the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA.
authors.forename: Yanfang Peipei
authors.initials: YP
authors.lastname: Zhu
authors.affiliation: From the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA.
authors.forename: Graham D
authors.initials: GD
authors.lastname: Thomas
authors.affiliation: From the Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA. Hedrick@lji.org.
authors.forename: Catherine C
authors.initials: CC
authors.lastname: Hedrick
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000145:classification / Q000276:immunology / Q000502:physiology*; D002454:Cell Differentiation; D060833:Cellular Microenvironment; D005786:Gene Expression Regulation; D005838:Genotype; D006411:Hematopoiesis, Extramedullary; D006801:Humans; D035683:MicroRNAs / Q000235:genetics / Q000378:metabolism; D009000:Monocytes / Q000145:classification / Q000276:immunology / Q000502:physiology*; D038042:Myelopoiesis; D010641:Phenotype; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism; D014158:Transcription, Genetic
chemical_list: D035683:MicroRNAs; D014157:Transcription Factors
keywords: atherosclerosis; bone marrow; microRNAs; monocytes; transcription factors