title: A Multifunctional Biomaterial with NIR Long Persistent Phosphorescence, Photothermal Response and Magnetism.
abstract: There are many reports on long persistent phosphors (LPPs) applied in bioimaging. However, there are few reports on LPPs applied in photothermal therapy (PTT), and an integrated system with multiple functions of diagnosis and therapy. In this work, we fabricate effective multifunctional phosphors Zn3 Ga2 SnO8 : Cr(3+) , Nd(3+) , Gd(3+) with NIR persistent phosphorescence, photothermal response and magnetism. Such featured materials can act as NIR optical biolabels and magnetic resonance imaging (MRI) contrast agents for tracking the early cancer cells, but also as photothermal therapeutic agent for killing the cancer cells. This new multifunctional biomaterial is expected to open a new possibility of setting up an advanced imaging-guided therapy system featuring a high resolution for bioimaging and low side effects for the photothermal ablation of tumors.
authors.affiliation: State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied Techniques, South China University of Technology, Guangzhou, 510640, P.R. China.
authors.forename: Yiling
authors.initials: Y
authors.lastname: Wu
authors.affiliation: School of Physics & Optoelectronic Engineering, Guangdong University of Technology, Guangzhou, 510006, P.R. China. msliyang@scut.edu.cn.
authors.forename: Yang
authors.initials: Y
authors.lastname: Li
authors.affiliation: State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied Techniques, South China University of Technology, Guangzhou, 510640, P.R. China.
authors.forename: Xixi
authors.initials: X
authors.lastname: Qin
authors.affiliation: State Key Laboratory of Luminescent Materials and Devices, Guangdong Provincial Key Laboratory of Fiber Laser Materials and Applied Techniques, South China University of Technology, Guangzhou, 510640, P.R. China. qjr@scut.edu.cn.|College of Optical Science and Engineering, Zhejiang University, Hangzhou, 310007, P.R. China. qjr@scut.edu.cn.
authors.forename: Jianrong
authors.initials: J
authors.lastname: Qiu
keywords: long persistent phosphors; magnetism; multifunctional; photothermal response