title: Outcome after fixation of metastatic proximal femoral fractures: A systematic review of 40 studies.
abstract: Endoprosthetic reconstruction, intramedullary nailing, and open reduction internal fixation (ORIF) are the most commonly practiced surgical strategies for treatment of metastatic proximal femoral fractures. This review describes functional outcome, local, and systemic complications. All three surgical strategies result in reasonable function on average; however, wide ranges indicate that both poor and good functional levels are obtained. We found that the overall reoperation rate was comparable for endoprosthesis and intramedullary nailing, but was higher for ORIF. J. Surg. Oncol. 2016;114:507-519. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Orthopaedic Surgery, Orthopaedic Oncology Service Boston, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts.
authors.forename: Stein J
authors.initials: SJ
authors.lastname: Janssen
authors.affiliation: Department of Orthopaedic Surgery, Orthopaedic Oncology Service Boston, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts.
authors.forename: Teun
authors.initials: T
authors.lastname: Teunis
authors.affiliation: Department of Orthopaedic Surgery, Orthopaedic Oncology Service Boston, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts.
authors.forename: Francis J
authors.initials: FJ
authors.lastname: Hornicek
authors.affiliation: Department of Orthopaedic Surgery, Academic Medical Center-University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: C Niek
authors.initials: CN
authors.lastname: van Dijk
authors.affiliation: Department of Orthopaedic Surgery, Academic Medical Center-University of Amsterdam, Amsterdam, The Netherlands.
authors.forename: Jos A M
authors.initials: JA
authors.lastname: Bramer
authors.affiliation: Department of Orthopaedic Surgery, Orthopaedic Oncology Service Boston, Massachusetts General Hospital-Harvard Medical School, Boston, Massachusetts.
authors.forename: Joseph H
authors.initials: JH
authors.lastname: Schwab
mesh_terms: D000368:Aged; D005260:Female; D005264:Femoral Fractures / Q000601:surgery*; D005266:Femoral Neoplasms / Q000150:complications / Q000556:secondary*; D005593:Fracture Fixation, Internal / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D019919:Prosthesis Implantation; D012086:Reoperation
keywords: bone; cancer; fracture; osseous; pathological