title: [Not Available].
abstract: Local Bacillus Calmette-Guerin (BCG) immunotherapy is an effective and widely used treatment for superficial bladder carcinoma. Local side effects are frequent, whereas systemic side effects are rare, but more serious. We report four cases of systemic BCG reaction. Although uncommon, this infectious complication of BCG therapy should always be considered in the appropriate clinical setting. The best approach to minimize this complication is a strict compliance with precautions and a close and rigorous surveillance of this drug.
authors.affiliation: Service d'Urologie, Hôpital Charles Nicolle, Tunis, Tunisie.. Electronic address: momosfa@yahoo.fr.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Sfaxi
authors.affiliation: Laboratoire National de Contrôle des Vaccins, Sérums et autres Produits Biologiques, Institut Pasteur, Tunis, Tunisie.
authors.forename: Houda
authors.initials: H
authors.lastname: Langar
authors.affiliation: Service d'Urologie, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Akrem
authors.initials: A
authors.lastname: Ouni
authors.affiliation: Laboratoire National de Contrôle des Vaccins, Sérums et autres Produits Biologiques, Institut Pasteur, Tunis, Tunisie.
authors.forename: Yosra
authors.initials: Y
authors.lastname: Riahi
authors.affiliation: Centre national de pharmacovigilance, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Sihem El
authors.initials: SE
authors.lastname: Aidli
authors.affiliation: Centre national de pharmacovigilance, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Riadh
authors.initials: R
authors.lastname: Daghfous
authors.affiliation: Laboratoire National de Contrôle des Vaccins, Sérums et autres Produits Biologiques, Institut Pasteur, Tunis, Tunisie.
authors.forename: Abdeladhim Ben
authors.initials: AB
authors.lastname: Abdeladhim
authors.affiliation: Service d'Urologie, Hôpital Charles Nicolle, Tunis, Tunisie.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Chébil
keywords: BCG-therapy; BCG-thérapie endovésicale; adverse drug reactions; complications systémiques; effet indésirable; superficial bladder tumour; systemic complication; tumeurs superficielles de la vessie