title: The Osseointegration Group of Australia Accelerated Protocol (OGAAP-1) for two-stage osseointegrated reconstruction of amputated limbs.
abstract: OBJECTIVE
  This study describes the Osseointegration Group of Australia's Accelerated Protocol two-stage strategy (OGAAP-1) for the osseointegrated reconstruction of amputated limbs.
  
  
  METHODS
  We report clinical outcomes in 50 unilateral trans-femoral amputees with a mean age of 49.4 years (24 to 73), with a minimum one-year follow-up. Outcome measures included the Questionnaire for persons with a Trans-Femoral Amputation, the health assessment questionnaire Short-Form-36 Health Survey, the Amputation Mobility Predictor scores presented as K-levels, 6 Minute Walk Test and timed up and go tests. Adverse events included soft-tissue problems, infection, fractures and failure of the implant.
  
  
  RESULTS
  Our results demonstrated statistically significant improvements in all five outcome measures. A total of 27 patients experienced adverse events but at the conclusion of the study, all 50 were walking on osseointegrated prostheses.
  
  
  CONCLUSIONS
  These results demonstrate that osseointegrated prostheses are a suitable alternative to socket-fit devices for amputees experiencing socket-related discomfort and that our strategy offers more rapid progress to walking than other similar protocols. Cite this article: Bone Joint J 2016;98-B:952-60.
authors.affiliation: The Australian School of Advanced Medicine, Macquarie University, Suite 303 Level 3, 2 Technology Place, North Ryde, NSW, 2109, Australia.
authors.forename: M Al
authors.initials: MA
authors.lastname: Muderis
authors.affiliation: Royal Brisbane Hospital, Level 7, Ned Hanlon Building Butterfield Street, Herston, Brisbane, QLD, 4029, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Tetsworth
authors.affiliation: University of Notre Dame Australia, 160 Oxford Street, Sydney, NSW, 2010, Australia.
authors.forename: A
authors.initials: A
authors.lastname: Khemka
authors.affiliation: Norwest Private Hospital, Suite G3, 9 Norbrik Drive, Bella Vista, NSW, 2153, Australia.
authors.forename: S
authors.initials: S
authors.lastname: Wilmot
authors.affiliation: Norwest Private Hospital, Suite G3, 9 Norbrik Drive, Bella Vista, NSW, 2153, Australia.
authors.forename: B
authors.initials: B
authors.lastname: Bosley
authors.affiliation: University of Notre Dame Australia, 160 Oxford Street, Sydney, NSW, 2010, Australia.
authors.forename: S J
authors.initials: SJ
authors.lastname: Lord
authors.affiliation: Institute of Health and Biomedical Innovation at Queensland University of Technology, 60 Musk Avenue, Kevin Grove, Brisbane, 4059, Australia.
authors.forename: V
authors.initials: V
authors.lastname: Glatt
mesh_terms: D000328:Adult; D000368:Aged; D000671:Amputation, Surgical; D000674:Amputees / Q000534:rehabilitation; D001186:Artificial Limbs; D001315:Australia; D015331:Cohort Studies; D005260:Female; D005269:Femur / Q000601:surgery*; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D008875:Middle Aged; D016348:Osseointegration; D026741:Physical Therapy Modalities; D011182:Postoperative Care; D011183:Postoperative Complications; D019919:Prosthesis Implantation / Q000379:methods; D016138:Walking; D055815:Young Adult
keywords: Bone-anchored prosthesis; Lower limb amputation; Lower limb reconstructive surgery; Osseointegration; Prosthetics; Rehabilitation