title: Synthesis of Aminobenzoic Acid Derivatives via Chemoselective Carbene Insertion into the -NH Bond Catalyzed by Cu(I) Complex.
abstract: Phosphine ligand stabilized air-stable Cu(I) complexes have been successfully used to functionalize the aromatic aminobenzoic acids in a chemoselective manner without implementing protection and deprotection strategy under mild reaction conditions. This chemoselective carbene insertion into -NH bond over -COOH and -OH bonds leads to the wide range of carboxy and hydroxy functionalized α-amino esters (27 examples). All of the isolated new products have been fully characterized using standard analytical methods.
authors.affiliation: Catalysis and Energy Laboratory, Department of Chemistry, Pondicherry University (A Central University) , Puducherry 605014, India.
authors.forename: Kankanala
authors.initials: K
authors.lastname: Ramakrishna
authors.affiliation: Catalysis and Energy Laboratory, Department of Chemistry, Pondicherry University (A Central University) , Puducherry 605014, India.
authors.forename: Chinnappan
authors.initials: C
authors.lastname: Sivasankar