title: A Perioperative Risk Comparison of Posterior Vault Distraction Osteogenesis in an Older Pediatric Population.
abstract: There is a growing literature on the advantages of posterior cranial vault distraction osteogenesis (PVDO) in infants, particularly those with syndromic and multisuture craniosynostosis. This study aims to compare perioperative outcomes of PVDO in older patients to those of infants. A prospective craniofacial database was queried for patients aged 5 and older undergoing PVDO; controls were diagnosis-matched infants. Demographic, perioperative, and distraction data was compared using a 2-sample t test and Fisher exact test.Twenty patients met inclusion criteria, and all had syndromic craniosynostosis. Mean age was 9.2 years for the older group, and 0.7 years for the younger. Older children had less weight-based blood loss (mean 58.6 ± 38.8 versus 14.6 ± 7.0 cc/kg, control versus older, P = 0.0092) and weight-based transfusion (mean 70.1 ± 37.2 versus 21.2 ± 9.9 cc/kg, control versus older, P = 0.0023); other perioperative variables were similar including duration of surgery, length of stay, distance distracted, time in consolidation, and length of follow-up. All patients in both groups successfully completed PVDO, and all older patients had resolution of papilledema and/or headaches. One from each group developed a wound infection that was treated with oral antibiotics.Posterior cranial vault distraction osteogenesis is a safe and efficacious for cranial vault expansion in syndromic craniosynostosis, with similar perioperative outcomes in older children as compared to infants. Posterior cranial vault distraction osteogenesis may be a reasonable alternative in older syndromic patients with acceptable frontal morphology and concerns for increased intracranial pressure.
authors.affiliation: Department of Surgery, The Children's Hospital of Philadelphia, The University of Pennsylvania, Philadelphia, PA.
authors.forename: Jing
authors.initials: J
authors.lastname: Li
authors.forename: Patrick A
authors.initials: PA
authors.lastname: Gerety
authors.forename: Wen
authors.initials: W
authors.lastname: Xu
authors.forename: Scott P
authors.initials: SP
authors.lastname: Bartlett
authors.forename: Jesse A
authors.initials: JA
authors.lastname: Taylor
mesh_terms: D002648:Child; D002675:Child, Preschool; D003398:Craniosynostoses / Q000150:complications / Q000601:surgery*; D005260:Female; D006801:Humans; D007223:Infant; D019586:Intracranial Hypertension / Q000209:etiology / Q000601:surgery; D008297:Male; D019857:Osteogenesis, Distraction / Q000379:methods*; D059035:Perioperative Period; D011446:Prospective Studies; D012307:Risk Factors; D012886:Skull / Q000601:surgery*