title: Lasiodiplodia species fungal osteomyelitis in a multiple myeloma patient.
abstract: Lasiodiplodia species are environmental fungi that have been reported as a cause of infection in both immunocompetent and immunocompromised patients. We present a case of fungal osteomyelitis caused by Lasiodiplodia species in a patient with multiple myeloma after autologous stem cell transplant. The patient was successfully treated with a combination of surgery and oral voriconzole. To the best of our knowledge, this is the first reported case of fungal osteomyelitis caused by Lasiodiplodia species.
authors.affiliation: Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA. mmohan@uams.edu.
authors.forename: M
authors.initials: M
authors.lastname: Mohan
authors.affiliation: Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: S C
authors.initials: SC
authors.lastname: Shalin
authors.affiliation: Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: A
authors.initials: A
authors.lastname: Kothari
authors.affiliation: Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: J C C
authors.initials: JC
authors.lastname: Rico
authors.affiliation: Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: K
authors.initials: K
authors.lastname: Caradine
authors.affiliation: Division of Infectious Diseases and Myeloma Institute, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.
authors.forename: M
authors.initials: M
authors.lastname: Burgess
mesh_terms: D000368:Aged; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D000671:Amputation, Surgical; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000008:administration & dosage / Q000627:therapeutic use; D001203:Ascomycota / Q000302:isolation & purification*; D001706:Biopsy; D001772:Blood Cell Count; D017809:Fatal Outcome; D018380:Hematopoietic Stem Cell Transplantation / Q000009:adverse effects*; D006801:Humans; D016867:Immunocompromised Host; D008279:Magnetic Resonance Imaging; D008297:Male; D009101:Multiple Myeloma / Q000628:therapy*; D010019:Osteomyelitis / Q000097:blood / Q000382:microbiology* / Q000473:pathology / Q000628:therapy*; D012867:Skin / Q000473:pathology; D014034:Toes / Q000473:pathology; D014182:Transplantation, Autologous / Q000009:adverse effects; D016312:Treatment Refusal; D065819:Voriconazole / Q000008:administration & dosage / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D000970:Antineoplastic Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B; D065819:Voriconazole
keywords: Lasiodiplodia species; fungal osteomyelitis; multiple myeloma