title: In Vivo MRI and X-Ray Bifunctional Imaging of Polymeric Composite Supplemented with GdPO4 ·H2 O Nanobundles for Tracing Bone Implant and Bone Regeneration.
abstract: Homogeneous and monodisperse GdPO4 ·H2 O nanobundles are successfully synthesized via a solvothermal method. Then, GdPO4 ·H2 O are incorporated into the composite of hydroxyapatite and poly(lactic-co-glycolic acid) to obtain a biodegradable and traceable bone implant. After implanted, the GdPO4 ·H2 O/HA/PLGA implant and the newly formed bone can be easily traced and observed through the combination of magnetic resonance imaging and X-ray imaging.
authors.affiliation: College of Chemistry, Jilin University, Changchun, 130012, P. R. China.|Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Huang
authors.affiliation: China-Japan Union Hospital, Jilin University, Changchun, 130021, P. R. China.
authors.forename: Zhongwen
authors.initials: Z
authors.lastname: Lv
authors.affiliation: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.
authors.forename: Zongliang
authors.initials: Z
authors.lastname: Wang
authors.affiliation: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.|School of Public Health, Jilin University, Changchun, 130021, P. R. China.
authors.forename: Tianlin
authors.initials: T
authors.lastname: Gao
authors.affiliation: Department of Foot and Ankle Surgery, The Second Hospital of Shandong University, Jinan, 250000, P. R. China.
authors.forename: Ning
authors.initials: N
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China.
authors.forename: Min
authors.initials: M
authors.lastname: Guo
authors.affiliation: College of Chemistry, Jilin University, Changchun, 130012, P. R. China. zouhf@jlu.edu.cn.
authors.forename: Haifeng
authors.initials: H
authors.lastname: Zou
authors.affiliation: Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, 130022, P. R. China. zhangpb@ciac.ac.cn.
authors.forename: Peibiao
authors.initials: P
authors.lastname: Zhang
mesh_terms: D020341:Absorbable Implants; D000818:Animals; D001861:Bone Regeneration; D002460:Cell Line; D003287:Contrast Media / Q000737:chemistry / Q000494:pharmacology; D017886:Durapatite / Q000737:chemistry / Q000494:pharmacology; D005682:Gadolinium / Q000737:chemistry / Q000494:pharmacology; D008279:Magnetic Resonance Imaging; D051379:Mice; D053758:Nanoparticles / Q000737:chemistry / Q000627:therapeutic use; D014057:Tomography, X-Ray Computed
chemical_list: D003287:Contrast Media; D017886:Durapatite; D005682:Gadolinium
keywords: MR imaging; bone repair; gadolinium phosphate; hydroxyapatite; poly(lactic-co-glycolic acid); radiography