title: Reduction of misregistration on cerebral four-dimensional computed tomography angiography images using advanced patient motion correction reconstruction.
abstract: OBJECTIVE
  The aim of this study was to evaluate whether advanced patient motion correction (APMC) can reduce the misregistration of pixels between the different X-ray tube positions in four-dimensional CT angiography (4D-CTA).
  
  
  METHODS
  Eight patients with intracranial aneurysms were included in this retrospective study. We compared the CTA images with APMC reconstruction and half-scan reconstruction with regard to the following 3 items: (1) bone misalignment area; (2) image noise; and (3) aneurysm volume change.
  
  
  RESULTS
  The bone misalignment area and image noise were significantly reduced in the APMC images, as compared to that in the half-scan reconstruction images (bone misalignment area: 33.0 ± 18.1 cm(3) vs 152.0 ± 72.2 cm(3), respectively; p < 0.001) (image noise at pons: 9.70 ± 2.58 vs 15.16 ± 5.02, respectively, p < 0.001). The aneurysm volume and volume variance were significantly smaller in the APMC reconstruction than those in the half-scan reconstruction (volume: 1107.2 ± 1813.8 mm(3) vs 1135.1 ± 1853.8 mm(3); p < 0.05; coefficient of variation: 0.0291 ± 0.014 vs 0.0463 ± 0.026, p < 0.05, respectively).
  
  
  CONCLUSIONS
  Our results show that APMC reduces the reconstruction related misregistration between the cardiac phases compared to half-scan reconstruction.
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Yuki
authors.initials: Y
authors.lastname: Kunitomi
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. watanabe@radiol.med.osaka-u.ac.jp.
authors.forename: Yoshiyuki
authors.initials: Y
authors.lastname: Watanabe
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Atsuko
authors.initials: A
authors.lastname: Arisawa
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Akio
authors.initials: A
authors.lastname: Tsukabe
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Hisashi
authors.initials: H
authors.lastname: Tanaka
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Hiroto
authors.initials: H
authors.lastname: Takahashi
authors.affiliation: Department of Neurosurgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Takeo
authors.initials: T
authors.lastname: Nishida
authors.affiliation: Department of Neurosurgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, 3-3 Nakamichi 1-Chome, Higashinari-Ku, Osaka, 537-8511, Japan.
authors.forename: Manabu
authors.initials: M
authors.lastname: Kinoshita
authors.affiliation: Department of Neurosurgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Hajime
authors.initials: H
authors.lastname: Nakamura
authors.affiliation: Department of Diagnostic and Interventional Radiology, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors.forename: Noriyuki
authors.initials: N
authors.lastname: Tomiyama
mesh_terms: D000368:Aged; D001921:Brain / Q000000981:diagnostic imaging; D002533:Cerebral Angiography / Q000379:methods*; D000072226:Computed Tomography Angiography / Q000379:methods*; D005260:Female; D056973:Four-Dimensional Computed Tomography / Q000379:methods*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods*; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging*; D008297:Male; D008875:Middle Aged; D011857:Radiographic Image Interpretation, Computer-Assisted / Q000379:methods*; D015203:Reproducibility of Results; D012189:Retrospective Studies; D012680:Sensitivity and Specificity
keywords: 4D-CTA; Brain aneurysm; Different orbital angle related location gap; Motion correction