title: Improved non-invasive Optical Coherence Tomography detection of different engineered nanoparticles in food-mimicking matrices.
abstract: Food industry and regulators require fast and reliable analytical methods for quality control. This especially counts for the detection of engineered nanomaterials (ENMs) in food products. Respective EU regulation is in force, but the development of appropriate methods is still underway. This paper updates the scope of Optical Coherence Tomography (OCT) for ENM/food matrix analysis. A range of nanomaterials and composites - Au@SiO2, Ag, Ag@SiO2 and SiO2 - in a simplified food matrix was investigated. The earlier finding of linear dependencies between concentration in the dispersion and light responses could be reproduced. Being able to analyse non-invasively for a relevant industrial compound such as SiO2, makes OCT an excellent candidate for screening purposes.
authors.affiliation: European Commission, Joint Research Centre, Institute for Reference Materials and Measurements (IRMM), Retieseweg 111, 2440 Geel, Belgium.
authors.forename: Ringo
authors.initials: R
authors.lastname: Grombe
authors.affiliation: Technische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fetscherstraße 74, 01307 Dresden, Germany.
authors.forename: Lars
authors.initials: L
authors.lastname: Kirsten
authors.affiliation: Technische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fetscherstraße 74, 01307 Dresden, Germany.
authors.forename: Mirko
authors.initials: M
authors.lastname: Mehner
authors.affiliation: European Commission, Joint Research Centre, Institute for Reference Materials and Measurements (IRMM), Retieseweg 111, 2440 Geel, Belgium. Electronic address: thomas.linsinger@ec.europa.eu.
authors.forename: Thomas P J
authors.initials: TP
authors.lastname: Linsinger
authors.affiliation: Technische Universität Dresden, Faculty of Medicine Carl Gustav Carus, Department of Anesthesiology and Intensive Care Medicine, Clinical Sensoring and Monitoring, Fetscherstraße 74, 01307 Dresden, Germany.
authors.forename: Edmund
authors.initials: E
authors.lastname: Koch
mesh_terms: D002616:Chemical Engineering / Q000379:methods*; D005504:Food Analysis / Q000379:methods*; D049329:Nanostructures / Q000032:analysis* / Q000737:chemistry*; D041623:Tomography, Optical Coherence / Q000379:methods*
keywords: Colloidal gold (PubChem CID: 23985); Colloidal silica (PubChem CID: 24261); Colloidal silver (PubChem CID: 23954); Food additive; Nanomaterial; Non-invasive screening; Optical Coherence Tomography (OCT); Silica