title: Synchronization of the Flow and Pressure Waves Obtained With Non-Simultaneous Multipoint Measurements.
abstract: The use of measured data as boundary conditions renders hemodynamic simulations more patient-specific. However, synchronized acquisition of data at multiple locations is often difficult in clinical practice. This study proposes a method for resynchronizing measured data for use as boundary conditions for flow simulations using frequency analyses, and discusses the optimal cut-off frequency for differentiating cardiac and respiratory variation in hemodynamic data during resynchronization. To demonstrate the utility of the method, a Fontan circulation, which is the final palliative result with single-ventricle physiology, was used. The results suggest that it is optimal to set a cut-off frequency that gives a local minimum in the power spectrum that is slightly lower than the peak frequency of the heartbeat. Additionally, the total energy loss depended on the cut-off frequency, although the overall flow patterns appeared to be similar. The method is applicable to cardiovascular systems other than the Fontan circulation, where hemodynamic data with multifactorial fluctuations are required at various locations but simultaneous measurements are not possible.
authors.affiliation: Department of Mechanical Engineering, Saitama University.
authors.forename: Shinji
authors.initials: S
authors.lastname: Goto
authors.forename: Masanori
authors.initials: M
authors.lastname: Nakamura
authors.forename: Keiichi
authors.initials: K
authors.lastname: Itatani
authors.forename: Shohei
authors.initials: S
authors.lastname: Miyazaki
authors.forename: Norihiko
authors.initials: N
authors.lastname: Oka
authors.forename: Takashi
authors.initials: T
authors.lastname: Honda
authors.forename: Tadashi
authors.initials: T
authors.lastname: Kitamura
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Horai
authors.forename: Masahiro
authors.initials: M
authors.lastname: Ishii
authors.forename: Kagami
authors.initials: K
authors.lastname: Miyaji
mesh_terms: D003198:Computer Simulation; D004867:Equipment Design; D018729:Fontan Procedure; D006439:Hemodynamics; D006801:Humans; D008955:Models, Cardiovascular; D061810:One-Lung Ventilation / Q000379:methods