title: Giant congenital melanocytic nevus in a bulgarian newborn.
abstract: Giant congenital melanocytic nevus (GCMN) is a rare disorder affecting 1 in 200,000500,000 live births. Central nervous system defects such as spina bifida, meningocele, Dandy Walker malformation may accompany it and thus cause significant morbidity. Despite the related risk for malignant transformation, GCMNs may be associated with neurocutaneous melanosis, a rare syndrome in which a giant CMN or multiple smaller CMNs are accompanied by melanocytic deposition in the brain and the spinal cord. We present a case of a 5-day-old newborn with giant congenital melanocytic nevus on his back, as we discuss the diagnostic and treatment approach.
authors.affiliation: Onkoderma- Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria; Department of Dermatology and Venereology, Medical University of Plovdiv, Medical Faculty, Plovdiv, Bulgaria.
authors.forename: A A
authors.initials: AA
authors.lastname: Chokoeva
authors.affiliation: History Department, G. Marconi University, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Fioranelli
authors.affiliation: University B.I.S. Group of Institutions, Punjab Technical University, Punjab, India.
authors.forename: M G
authors.initials: MG
authors.lastname: Roccia
authors.affiliation: Department of Dermatology, University of Rome G. Marconi Rome, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Lotti
authors.affiliation: Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Wollina
authors.affiliation: Medical Institute of Ministry of Interior (MVR-Sofia), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia, Bulgaria.
authors.forename: G
authors.initials: G
authors.lastname: Tchernev
mesh_terms: D002031:Bulgaria; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D020752:Neurocutaneous Syndromes / Q000151:congenital / Q000175:diagnosis / Q000628:therapy; D009508:Nevus, Pigmented / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy; D012878:Skin Neoplasms / Q000151:congenital* / Q000175:diagnosis / Q000628:therapy