title: Reference Values for The Triglyceride to High-Density Lipoprotein Cholesterol Ratio and Non-High-Density Lipoprotein Cholesterol in Korean Children and Adolescents: The Korean National Health and Nutrition Examination Surveys 2007-2013.
abstract: OBJECTIVE
  Cholesterol levels vary throughout childhood and adolescence. The aim of the present study was to evaluate and identify age- and gender-specific reference values for serum lipid concentrations including non-high-density lipoprotein cholesterol (non-HDL-C) and the triglyceride to HDL-C ratio (TG/HDL-C ratio) in apparently healthy Korean children and adolescents.
  
  
  METHODS
  A total of 6197 participants aged 10 to 19 years old from the 2007-2013 Korean National Health and Nutrition Examination Survey were analyzed. Serum lipid concentrations were evaluated according to age and gender.
  
  
  RESULTS
  The overall mean concentration of non-HDL-C was 105.5±25.6 mg/dL, with a significant gender difference: 103.3±26.1 mg/dL in boys and 107.9±24.7 mg/dL in girls (p=0.028). The median values of non-HDL-C concentrations in boys and girls, respectively, were 111 and 112 mg/dL in the 10-year-old age group, 95 and 103 mg/dL in the 15-year-old age group, and 109 and 103 mg/dL in the 19-year-old age group. The overall mean TG/HDL-C ratio was 1.74±1.22, and there were no significant gender differences: 1.77±1.25 in boys and 1.72±1.22 in girls (p=0.183). The median values of the TG/HDL-C ratio in boys and girls were 1.16 and 1.00 in the 10-year-olds, 1.54 and 0.95 in the 15-year-olds, and 1.74 and 0.84 in the 19-year-olds, respectively.
  
  
  CONCLUSIONS
  Age- and gender-specific reference values for non-HDL-C and for the TG/HDL-C ratio in children and adolescents could provide valuable information for individualized interpretations of lipid profiles and interventions as well as for strategies to prevent and manage childhood and adolescent dyslipidemia.
authors.affiliation: Department of Pediatrics, Hallym University, College of Medicine.
authors.forename: Young Suk
authors.initials: YS
authors.lastname: Shim
authors.forename: Joon Woo
authors.initials: JW
authors.lastname: Baek
authors.forename: Min Jae
authors.initials: MJ
authors.lastname: Kang
authors.forename: Yeon Jeong
authors.initials: YJ
authors.lastname: Oh
authors.forename: Seung
authors.initials: S
authors.lastname: Yang
authors.forename: Ii Tae
authors.initials: IT
authors.lastname: Hwang
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D002648:Child; D008076:Cholesterol, HDL / Q000032:analysis*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D009749:Nutrition Surveys; D012016:Reference Values; D056910:Republic of Korea; D012737:Sex Factors; D014280:Triglycerides / Q000032:analysis*; D055815:Young Adult
chemical_list: D008076:Cholesterol, HDL; D014280:Triglycerides