title: Influence of hyperbilirubinemia on neonatal sucking.
abstract: Mothers of hyperbilirubinemic newborns frequently report to us that their infant is feeding poorly. As poor feeding in an extremely hyperbilirubinemic newborn may be an early sign of bilirubin encephalopathy, we hypothesized that neonatal hyperbilirubinemia would suppress the volume of feed ingested and diminish sucking parameters in comparison with minimally jaundiced neonates.
  
  
  
  To determine whether hyperbilirubinemia does diminish feeding and sucking in neonates.
  
  
  
  Neonates in a well-baby nursery with serum total bilirubin (STB) ≥15.0mg/dL were compared with those with transcutaneous bilirubin ≤10mg/dL. Neonur, a modification of Krohn's Nutritive Sucking Apparatus, was used to quantify sucking parameters. Measurements during a 5min feeding period included volume ingested (measured manually), number of sucks, average maximum sucking pressure, number of bursts, average burst duration, pause between bursts duration, number of sucks per burst, and average intersuck interval. Outcome measures were volume ingested and, presuming decreased volume, sucking parameter analysis would determine the component affected by hyperbilirubinemia.
  
  
  
  17 hyperbilirubinemic newborns (STB 17.8±1.6mg/dL) were compared with 24 controls, all with transcutaneous bilirubin <10.0mg/dL. The volume of feed ingested was similar between the hyperbilirubinemic newborns and controls (30.00 [20.00-42.50] ml vs. 25.00 [15.00-30.00] ml, p=0.2) (median [95% confidence interval]). No significant differences were noted in any of the other sucking parameters measured.
  
  
  
  At concentrations of STB in the range of 15-20mg/dL, hyperbilirubinemia did not diminish feed volume or sucking parameters in term newborns. Poor feeding in moderately hyperbilirubinemic newborns cannot be attributed to the level of bilirubin per se.
authors.affiliation: Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel; The Faculty of Medicine of the Hebrew University, Jerusalem, Israel.
authors.forename: Ruben
authors.initials: R
authors.lastname: Bromiker
authors.affiliation: University of Pennsylvania School of Nursing and The Children's Hospital of Philadelphia, Philadelphia, PA.
authors.forename: Barbara
authors.initials: B
authors.lastname: Medoff-Cooper
authors.affiliation: The Faculty of Medicine of the Hebrew University, Jerusalem, Israel.
authors.forename: Hadar
authors.initials: H
authors.lastname: Flor-Hirsch
authors.affiliation: Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel; The Faculty of Medicine of the Hebrew University, Jerusalem, Israel. Electronic address: mkaplan@mail.huji.ac.il.
authors.forename: Michael
authors.initials: M
authors.lastname: Kaplan
mesh_terms: D016022:Case-Control Studies; D005260:Female; D006801:Humans; D051556:Hyperbilirubinemia, Neonatal / Q000175:diagnosis / Q000503:physiopathology*; D007231:Infant, Newborn; D008297:Male; D013391:Sucking Behavior
keywords: Neonatal hyperbilirubinemia; Newborn feeding; Newborn sucking