title: Cardiogenic Shock and Respiratory Failure in a Patient With Metastatic Melanoma Receiving Trametinib Therapy.
authors.affiliation: Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA; Harvard University, Cambridge, Massachusetts, USA.
authors.forename: Diane
authors.initials: D
authors.lastname: Tseng
authors.affiliation: Harvard University, Cambridge, Massachusetts, USA; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
authors.forename: Xenos L
authors.initials: XL
authors.lastname: Mason
authors.affiliation: Harvard University, Cambridge, Massachusetts, USA; Department of Medicine, Department of Cardiology, Cardio-Oncology Program, Massachusetts General Hospital, Boston, Massachusetts, USA.
authors.forename: Tomas G
authors.initials: TG
authors.lastname: Neilan
authors.affiliation: Harvard University, Cambridge, Massachusetts, USA; Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
authors.forename: Ryan J
authors.initials: RJ
authors.lastname: Sullivan
mesh_terms: D006801:Humans; D008545:Melanoma / Q000150:complications / Q000188:drug therapy* / Q000473:pathology; D011728:Pyridones / Q000009:adverse effects* / Q000627:therapeutic use; D011744:Pyrimidinones / Q000009:adverse effects* / Q000627:therapeutic use; D012131:Respiratory Insufficiency / Q000139:chemically induced / Q000503:physiopathology*; D012770:Shock, Cardiogenic / Q000139:chemically induced / Q000503:physiopathology*
chemical_list: D011728:Pyridones; D011744:Pyrimidinones; C560077:trametinib