title: Recurrent meningioma of the scalp after 13 years.
abstract: Meningiomas represent some of the most common types of tumour of the central nervous system. They are considered benign, with ∼1 in 1000 known to metastasise. We report a case of recurrent meningioma of the scalp 13 years following craniotomy to treat the primary. The recurrent tumour of the scalp was eventually excised 5 years later and the defect closed with an anterolateral thigh free flap in a joint procedure between the neurosurgeons and plastic surgeons. Histology of the scalp lesion confirmed a WHO grade I meningioma. Although a number of explanations for recurrent scalp meningiomas exist, the precise role of isolated genetic defects in scalp meningiomas is incomplete. The scalp meningioma in this case consisted of a complex karyotype suggestive of more aggressive disease. This case emphasises that cytogenetics may play a greater role in identifying more aggressive tumours than histology alone.
authors.affiliation: Leeds Teaching Hospitals NHS Trust, Leeds, UK.
authors.forename: Daniel Lee
authors.initials: DL
authors.lastname: Ashmore
authors.affiliation: Leeds Teaching Hospitals NHS Trust, Leeds, UK.
authors.forename: Rachel
authors.initials: R
authors.lastname: Clancy
authors.affiliation: Department of Neurosurgery, Leeds General Infirmary, Leeds, UK.
authors.forename: Paul D
authors.initials: PD
authors.lastname: Chumas
mesh_terms: D000328:Adult; D003399:Craniotomy; D005260:Female; D058752:Free Tissue Flaps; D006801:Humans; D008279:Magnetic Resonance Imaging; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging / Q000601:surgery*; D008579:Meningioma / Q000000981:diagnostic imaging / Q000601:surgery*; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000601:surgery*; D019651:Plastic Surgery Procedures / Q000379:methods*; D012535:Scalp / Q000000981:diagnostic imaging / Q000601:surgery*; D014057:Tomography, X-Ray Computed