title: Effects of Radioactive Iodine Ablation Therapy on Voice Quality.
abstract: OBJECTIVE
  The goal of this study was to evaluate the effects of radioactive iodine ablation therapy on voice quality of patients diagnosed with well-differentiated thyroid carcinoma.
  
  
  METHODS
  We enrolled 36 patients who underwent total or subtotal thyroidectomy due to well-differentiated thyroid carcinoma. Voice recordings from patients were analyzed for acoustic and aerodynamic voice. The Voice Handicap Index-10 was used for subjective analysis. The control group consisted of 36 healthy participants. Results taken before and after therapy were compared statistically.
  
  
  RESULTS
  There were no differences in the results taken before and after therapy for the radioactive iodine ablation group. The Voice Handicap Index-10 results did not differ between groups before and after therapy.
  
  
  CONCLUSIONS
  Radioactive iodine ablation therapy has no effect on voice quality objectively or subjectively.
authors.affiliation: Bahçelievler Government Hospital ENT Clinic, Turkey. Electronic address: imran_aydogdu@hotmail.com.
authors.forename: İmran
authors.initials: İ
authors.lastname: Aydoğdu
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Atar
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Ziya
authors.initials: Z
authors.lastname: Saltürk
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Sarı
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Enes
authors.initials: E
authors.lastname: Ataç
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Aydoğdu
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Muzaffer
authors.initials: M
authors.lastname: İnan
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Gökhan
authors.initials: G
authors.lastname: Mersinlioğlu
authors.affiliation: Okmeydanı Training and Research Hospital ENT Clinic, Turkey.
authors.forename: Yavuz
authors.initials: Y
authors.lastname: Uyar
mesh_terms: D055011:Ablation Techniques / Q000009:adverse effects; D000162:Acoustics; D000293:Adolescent; D000328:Adult; D002277:Carcinoma / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D016022:Case-Control Studies; D002454:Cell Differentiation; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D007457:Iodine Radioisotopes / Q000009:adverse effects; D008297:Male; D008875:Middle Aged; D011832:Radiation Injuries / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D018714:Radiotherapy, Adjuvant; D013061:Speech Acoustics; D013068:Speech Production Measurement; D011795:Surveys and Questionnaires; D013964:Thyroid Neoplasms / Q000473:pathology / Q000532:radiotherapy* / Q000601:surgery; D013965:Thyroidectomy; D016896:Treatment Outcome; D014831:Voice / Q000528:radiation effects*; D014832:Voice Disorders / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology; D055815:Young Adult
chemical_list: D007457:Iodine Radioisotopes
keywords: Acoustic analysis; Radioactive iodine therapy; Total thyroidectomy; Voice; Well-differentiated thyroid cancer