title: The Effects of Alcohol on Other Chronic Liver Diseases.
abstract: Alcohol consumption is often a comorbid condition in other chronic liver diseases. It has been shown to act in synergy to increase liver injury in viral hepatitis, hereditary hemochromatosis, and nonalcoholic fatty liver disease (NAFLD), leading to an increased risk of cirrhosis, hepatocellular carcinoma, and liver-related mortality. Data suggest that modest alcohol consumption may be inversely related to the risk of developing NAFLD and lower rates of progression of NAFLD to nonalcoholic steatohepatitis (NASH). This article reviews data on the relationship between alcohol consumption and other chronic liver diseases.
authors.affiliation: Division of Gastroenterology, University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19146, USA.
authors.forename: Christine C
authors.initials: CC
authors.lastname: Hsu
authors.affiliation: Swedish Liver Care Network, Swedish Medical Center, 1124 Columbia Street, Suite 600, Seattle, WA 98104, USA. Electronic address: kris.kowdley@swedish.org.
authors.forename: Kris V
authors.initials: KV
authors.lastname: Kowdley
mesh_terms: D000428:Alcohol Drinking / Q000009:adverse effects*; D001327:Autoimmune Diseases / Q000209:etiology; D002908:Chronic Disease; D006432:Hemochromatosis / Q000209:etiology; D019694:Hepatitis B, Chronic / Q000209:etiology; D019698:Hepatitis C, Chronic / Q000209:etiology; D006801:Humans; D008107:Liver Diseases / Q000209:etiology*; D065626:Non-alcoholic Fatty Liver Disease / Q000209:etiology; D012307:Risk Factors
keywords: Alcohol; Cirrhosis; Hepatitis B; Hepatitis C; Hepatocellular carcinoma; Nonalcoholic steatohepatitis (NASH)