title: Impact of a computer-assisted Screening, Brief Intervention and Referral to Treatment on reducing alcohol consumption among patients with hazardous drinking disorder in hospital emergency departments. The randomized BREVALCO trial.
abstract: To assess the impact of a computer-assisted Screening, Brief Intervention, and Referral to Treatment (SBIRT) on daily consumption of alcohol by patients with hazardous drinking disorder detected after systematic screening during their admission to an emergency department (ED).
  
  
  
  Two-arm, parallel group, multicentre, randomized controlled trial with a centralised computer-generated randomization procedure.
  
  
  
  Four EDs in university hospitals located in the Paris area in France.
  
  
  
  Patients admitted in the ED for any reason, with hazardous drinking disorder detected after systematic screening (i.e., Alcohol Use Disorder Identification Test score ≥5 for women and 8 for men OR self-reported alcohol consumption by week ≥7 drinks for women and 14 for men).
  
  
  
  The experimental intervention was computer-assisted SBIRT and the comparator was a placebo-controlled intervention (i.e., a computer-assisted education program on nutrition). Interventions were administered in the ED and followed by phone reinforcements at 1 and 3 months.
  
  
  
  The primary outcome was the mean number of alcohol drinks per day in the previous week, at 12 months. Results From May 2005 to February 2011, 286 patients were randomized to the computer-assisted SBIRT and 286 to the comparator intervention. The two groups did not differ in the primary outcome, with an adjusted mean difference of 0.12 (95% confidence interval, -0.88 to 1.11).
  
  
  
  There was no additional benefit of the computer-assisted alcohol SBIRT as compared with the computer-assisted education program on nutrition among patients with hazardous drinking disorder detected by systematic screening during their admission to an ED.
authors.affiliation: Department of Psychiatry and Addictive Medicine, Hôpital Bichat-Claude Bernard, Assistance Publique des Hôpitaux de Paris, Paris, France; Paris Diderot University - Paris VII, Paris, France. Electronic address: david.duroy@aphp.fr.
authors.forename: David
authors.initials: D
authors.lastname: Duroy
authors.affiliation: Centre d'Épidémiologie Clinique, Hôpital Hôtel Dieu, Assistance Publique des Hôpitaux de Paris, Paris, France; Paris Descartes University - Paris V, Paris, France; INSERM, UMR 1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), METHODS Team, Paris, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Boutron
authors.affiliation: Centre d'Épidémiologie Clinique, Hôpital Hôtel Dieu, Assistance Publique des Hôpitaux de Paris, Paris, France; Paris Descartes University - Paris V, Paris, France; INSERM, UMR 1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), METHODS Team, Paris, France.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Baron
authors.affiliation: Centre d'Épidémiologie Clinique, Hôpital Hôtel Dieu, Assistance Publique des Hôpitaux de Paris, Paris, France; Paris Descartes University - Paris V, Paris, France; INSERM, UMR 1153 Epidemiology and Biostatistics Sorbonne Paris Cité Center (CRESS), METHODS Team, Paris, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Ravaud
authors.affiliation: Paris Diderot University - Paris VII, Paris, France; Département d'Epidémiologie et Recherche Clinique/URC Paris-Nord, Hôpital Bichat-Claude Bernard, Assistance Publique des Hôpitaux de Paris, Paris, France; INSERM CIC-EC 1425 and ECEVE UMR 1123, Paris, France.
authors.forename: Candice
authors.initials: C
authors.lastname: Estellat
authors.affiliation: Department of Psychiatry and Addictive Medicine, Hôpital Bichat-Claude Bernard, Assistance Publique des Hôpitaux de Paris, Paris, France; Paris Diderot University - Paris VII, Paris, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Lejoyeux
mesh_terms: D000328:Adult; D000428:Alcohol Drinking / Q000453:epidemiology / Q000517:prevention & control*; D000437:Alcoholism / Q000175:diagnosis* / Q000453:epidemiology / Q000628:therapy*; D003936:Diagnosis, Computer-Assisted / Q000379:methods* / Q000639:trends; D004636:Emergency Service, Hospital; D005260:Female; D005500:Follow-Up Studies; D005602:France / Q000453:epidemiology; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods* / Q000639:trends; D008875:Middle Aged; D010865:Pilot Projects; D012017:Referral and Consultation; D016896:Treatment Outcome
keywords: Computer-assisted intervention; Emergency department; Hazardous drinking disorder; SBIRT