title: Extending accessible chemical space for the identification of novel leads.
authors.affiliation: a Department of Life Science Informatics, B-IT, LIMES Program Unit Chemical Biology and Medicinal Chemistry , Rheinische Friedrich-Wilhelms-Universität , Bonn , Germany.
authors.forename: Jürgen
authors.initials: J
authors.lastname: Bajorath
mesh_terms: D020650:Combinatorial Chemistry Techniques; D015195:Drug Design; D055808:Drug Discovery / Q000379:methods*; D006801:Humans; D054852:Small Molecule Libraries / Q000737:chemistry*
chemical_list: D054852:Small Molecule Libraries
keywords: Chemical space; diversity paradigm; fragment-based design; natural product-derived compounds; ultra-large chemical libraries