title: Recovery Versus Remission: Clinical Insights.
abstract: Adverse myocardial remodeling can be reversed by medical, surgical, and device therapies leading to reduced heart failure (HF) morbidity and mortality and significant improvements in the structure and function of the failing heart. The growing population of HF patients who experience a degree of myocardial improvement should be better studied in terms of long-term outcomes and underlying biology to more clearly define the difference between recovery and remission. These investigations should also be focused in determining whether in chronic HF patients complete myocardial recovery is achievable at a meaningful rate and help us better understand, predict, and manipulate cardiac recovery.
authors.affiliation: Molecular Medicine Program, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA.
authors.forename: Peter C
authors.initials: PC
authors.lastname: Ferrin
authors.affiliation: Molecular Medicine Program, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA.
authors.forename: Lauren
authors.initials: L
authors.lastname: McCreath
authors.affiliation: Division of Cardiovascular Medicine, University of Utah School of Medicine, Molecular Medicine Program, Eccles Institute of Human Genetics and UTAH Cardiac Transplant Program, Salt Lake City, Utah, USA.
authors.forename: Sutip
authors.initials: S
authors.lastname: Navankasattusas
authors.affiliation: Molecular Medicine Program, University of Utah, 15 North 2030 East, Salt Lake City, UT 84112, USA; Utah Transplantation Affiliated Hospitals (UTAH) Cardiac Transplant Program, University of Utah Health Sciences Center, Intermountain Medical Center, Veterans Affairs Salt Lake City Health Care System, 50 Medical Drive, Salt Lake City, UT 84132, USA. Electronic address: stavros.drakos@hsc.utah.edu.
authors.forename: Stavros G
authors.initials: SG
authors.lastname: Drakos
mesh_terms: D000072038:Cardiac Rehabilitation; D005260:Female; D006333:Heart Failure / Q000503:physiopathology* / Q000628:therapy*; D006801:Humans; D008297:Male; D057170:Translational Research, Biomedical; D020257:Ventricular Remodeling
keywords: Cardiomyopathy; Heart failure; Recovery; Remission; Reverse remodeling