title: Self-perceived Sleep Quality and Quantity in Adults With Asthma: Findings From the CosteAsma Study.
abstract: OBJECTIVE
  Nocturnal asthma symptoms are associated with poor sleep quality, excessive daytime sleepiness, and poor daytime functioning. The aim of this study was to describe self-perceived sleep quality and quantity in asthmatic adults in a real-world setting according to different determinants of patient health status.
  
  
  METHODS
  A cross-sectional, observational, seasonal, multiwave survey was designed. Allergists nationwide were asked to consecutively survey adult asthmatics aged 18 to 65 years, evenly distributed by seasons and asthma severity (Global Initiative for Asthma criteria). Sleep quality and quantity were assessed using the self-administered Medical Outcomes Study (MOS) Sleep Scale. The Asthma Control Test was applied to ascertain the degree of asthma symptom control.
  
  
  RESULTS
  A total of 1098 individuals (58.7% females, 41.2 [13.6] years) were analyzed. Asthma severity was associated with poor sleep quality and quantity; patients with more severe disease scored higher on the MOS Sleep Scale (P<.001) and also reported significantly fewer daily average hours of sleep (0.3-0.5 hours, P<.001). Level of symptom control and asthma severity were both associated with poor sleep quality and quantity, with the following mean MOS sleep problem index scores: 25.3 (fully controlled asthma), 26.4 (controlled), 32.6 (partly controlled), and 44.6 (uncontrolled) (P<.001), and 48.4 (severe asthma), 39.0 (moderate), 32.6 (mild), and 26.5 (intermittent) (P<.001). Sex was significantly associated with the summary MOS sleep problem index.
  
  
  CONCLUSIONS
  Sleep quality and quantity was significantly associated with poor health status in asthmatic patients. Guidelines should recommend asking about nocturnal asthma symptoms and encourage clinicians to take a global sleep history. Better control of nocturnal asthma symptoms could lead to improved sleep quality and a decrease in daytime sleep-related symptoms.
authors.affiliation: Medical Department, Pfizer S.L.U, Alcobendas, Madrid, Spain.
authors.forename: V
authors.initials: V
authors.lastname: Sanz de Burgoa
authors.affiliation: Health Economics and Outcomes Research Department, Pfizer S.L.U, Alcobendas, Madrid, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Rejas
authors.affiliation: Clínica de Asma y Alergia Dres Ojeda, Madrid, Spain.
authors.forename: P
authors.initials: P
authors.lastname: Ojeda
mesh_terms: D000328:Adult; D001249:Asthma / Q000503:physiopathology*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012649:Self Concept; D012890:Sleep
keywords: Asthma; Disability; MOS sleep scale; Real-world setting; Sleep quality and quantity