title: [Obesity Paradox and Stroke].
abstract: The obesity paradox suggests that overweight and obese patients of older age may have higher survival rates after stroke as compared to normalweight patients. However, the results need a cautious interpretation due to selection bias, treatment bias and different patients’ characteristics. Moreover, randomized studies that prove a benefit of weight reduction are still lacking. As obesity is an independet risk factor for stroke, weight reduction should still be recommended in overweight patients. Randomized-controlled studies are needed to prove the effect of weight reduction on morbidity and mortality after stroke.
authors.affiliation: 1 Neurozentrum Hirslanden, Zürich.
authors.forename: Ralf
authors.initials: R
authors.lastname: Baumgartner
authors.affiliation: 2 Neurologische Universitätsklinik, Inselspital, Bern.
authors.forename: Lisa
authors.initials: L
authors.lastname: Oesch
authors.affiliation: 2 Neurologische Universitätsklinik, Inselspital, Bern.
authors.forename: Hakan
authors.initials: H
authors.lastname: Sarikaya
mesh_terms: D015992:Body Mass Index; D002423:Cause of Death; D006801:Humans; D009765:Obesity / Q000401:mortality* / Q000628:therapy; D050177:Overweight / Q000401:mortality* / Q000628:therapy; D016032:Randomized Controlled Trials as Topic; D013223:Statistics as Topic; D020521:Stroke / Q000401:mortality* / Q000517:prevention & control; D015996:Survival Rate; D016896:Treatment Outcome; D015431:Weight Loss
keywords: Adipositas; Hirnschlag; Mortalität; Thrombolyse; morbidité et mortalité post accident vasculaire cérébral; mortality; oberity; obésité; overweight; risque cardiovasculaire; stroke; surcharge pondérale; thrombolysis; Übergewicht