title: [Disseminated necrobiotic xanthogranuloma].
abstract: Necrobiotic xanthogranuloma is a rare non-Langerhans-cell histiocytosis. A 62-year-old woman presented with yellowish erythematous plaques, nodules, and papules in the periorbital region and the extremities. She had a nodular tumor grown on the left upper lid that clinically resembled a keratoacanthoma. Histologically it was a xanthogranulomatous lesion. She suffered from monoclonal gammopathy of unknown significance of κ‑type. Treatment was realized with a combination of systemic dapsone/prednisolone and topical corticosteroids.
authors.affiliation: Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Klingner
authors.affiliation: Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland.
authors.forename: G
authors.initials: G
authors.lastname: Hansel
authors.affiliation: Institut für Pathologie "Georg Schmorl", Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Dresden, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Schönlebe
authors.affiliation: Klinik für Dermatologie und Allergologie, Krankenhaus Dresden-Friedrichstadt, Städtisches Klinikum, Akademisches Lehrkrankenhaus der TU Dresden, Friedrichstr. 41, 01067, Dresden, Deutschland. wollina-uw@khdf.de.
authors.forename: U
authors.initials: U
authors.lastname: Wollina
mesh_terms: D000893:Anti-Inflammatory Agents / Q000008:administration & dosage; D003937:Diagnosis, Differential; D005148:Facial Dermatoses / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D005260:Female; D006801:Humans; D007866:Leg / Q000473:pathology*; D008875:Middle Aged; D058252:Necrobiotic Xanthogranuloma / Q000175:diagnosis / Q000188:drug therapy* / Q000473:pathology*; D016896:Treatment Outcome
chemical_list: D000893:Anti-Inflammatory Agents
keywords: Corticosteroids; Dapsone; Dermatology; Monoclonal gammopathy of undetermined significance; Non-Langerhans-cell histiocytosis