title: Upregulation of Antioxidant Enzymes by ASS234, a Multitarget Directed Propargylamine for Alzheimer's Disease Therapy.
authors.affiliation: Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, Spain.
authors.forename: Eva
authors.initials: E
authors.lastname: Ramos
authors.affiliation: Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, Spain.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Romero
authors.affiliation: Laboratory of Medicinal Chemistry (IQOG, CSIC), Madrid, Spain.
authors.forename: José
authors.initials: J
authors.lastname: Marco-Contelles
authors.affiliation: Department of Toxicology and Pharmacology, Faculty of Veterinary Medicine, Complutense University of Madrid, Madrid, Spain.
authors.forename: Javier
authors.initials: J
authors.lastname: Del Pino
mesh_terms: D000544:Alzheimer Disease / Q000188:drug therapy*; D000818:Animals; D002374:Catalase / Q000235:genetics / Q000378:metabolism; D002800:Cholinesterase Inhibitors / Q000737:chemistry / Q000627:therapeutic use*; D006801:Humans; D007211:Indoles / Q000737:chemistry / Q000627:therapeutic use*; D010293:Pargyline / Q000031:analogs & derivatives / Q000627:therapeutic use; D010880:Piperidines / Q000737:chemistry / Q000627:therapeutic use*; D011437:Propylamines / Q000627:therapeutic use; D015398:Signal Transduction / Q000187:drug effects; D000072105:Superoxide Dismutase-1 / Q000235:genetics / Q000378:metabolism; D015854:Up-Regulation / Q000187:drug effects*
chemical_list: D002800:Cholinesterase Inhibitors; D007211:Indoles; C570530:N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine; D010880:Piperidines; D011437:Propylamines; C009054:propargylamine; D010293:Pargyline; D002374:Catalase; D000072105:Superoxide Dismutase-1