title: Comparison between Pentacam-HR and optical coherence tomographycentral corneal thickness measurements in healthy feline eyes.
abstract: OBJECTIVE
  To measure the central corneal thickness (CCT) in healthy feline eyes with Scheimpflug imaging (Pentacam, Pentacam(®) -HR) and to compare these values with those obtained with spectral-domain optical coherence tomography (OCT, Optovue(®) iVue).
  
  
  METHODS
  Thirty one sedated Domestic Short-haired cats.
  
  
  METHODS
  Two repeated CCT measurements were obtained from both eyes using Pentacam measured at the pupil center and corneal apex (CCTpupil and CCTapex ) and using SD-OCT (CCTOCT ). Agreement between the imaging modalities for CCT and intradevice repeatability was evaluated with Bland-Altman analysis. Mixed modeling was used to test for a difference between methods.
  
  
  RESULTS
  The calculated mean ± SD CCT was CCTOCT  = 584.93 ± 39.05 μm, CCTpupil  = 608.25 ± 47.26 μm, and CCTapex  = 606.41 ± 44.18 μm. There was a statistically significant difference between CCTOCT vs. CCTpupil (P < 0.0007) and CCTOCT vs. CCTapex (P < 0.0003) (n = 59 eyes). The 95% limits of agreement (LoA) for CCTOCT vs. CCTpupil was (-89.57 μm, 40.04 μm) and for CCTOCT vs. CCTapex was (-79.62 μm, 33.79 μm) (n = 59 eyes). 95% LoA between repeated CCT measurements by SD-OCT was (-10.23 μm, 9.32 μm) and by Pentacam was (-22.66 μm, 18.30 μm) at pupil and (-15.81 μm, 16.17 μm) at corneal apex (n = 11 eyes).
  
  
  CONCLUSIONS
  SD-OCT and Pentacam provide excellent CCT measurement repeatability. Pentacamapex is our recommended clinical setting for use of the Pentacam. The level of agreement between SD-OCT and Pentacam for CCT is good.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Colorado State University, Veterinary Teaching Hospital, 300 West Drake Road, Fort Collins, CO, 80523, USA.
authors.forename: Allison M
authors.initials: AM
authors.lastname: Cleymaet
authors.affiliation: Department of Statistics, College of Natural Sciences, Colorado State University, Veterinary Teaching Hospital, 300 West Drake Road, Fort Collins, CO, 80523, USA.
authors.forename: Ann M
authors.initials: AM
authors.lastname: Hess
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Colorado State University, Veterinary Teaching Hospital, 300 West Drake Road, Fort Collins, CO, 80523, USA.
authors.forename: Kate S
authors.initials: KS
authors.lastname: Freeman
mesh_terms: D000818:Animals; D002415:Cats / Q000033:anatomy & histology*; D003315:Cornea / Q000033:anatomy & histology*; D063171:Corneal Pachymetry / Q000379:methods / Q000662:veterinary*; D005260:Female; D008297:Male; D010781:Photography / Q000379:methods / Q000662:veterinary*; D012016:Reference Values; D041623:Tomography, Optical Coherence / Q000662:veterinary*
keywords: OCT; Pentacam; anterior segment; cornea; pachymetry; tomography