title: SerumTrace Elements in Febrile Seizure: A Case-Control Study.
abstract: OBJECTIVE
  Febrile seizure (FS) is one of the most common neurological problems during childhood.Pathogenesis of febrile convulsion is unknown. This study investigated some trace elements among children admitted with FS compared with thoseof febrile without seizure attacks.
  
  
  METHODS
  This case-control study was conducted on48 children (6 months to 5 yrold) diagnosed with febrile seizure as the cases and 48 age-matched febrile children as the control group. Serum levels of magnesium, calcium, sodium, potassium, and serum zinc were measured. Statistical analysis was performed with SPSS (version 15) using Student t-test.
  
  
  RESULTS
  There were no significant differences between the cases and controls in terms of gender or age. The means of serum level of zinc, sodium, calcium and magnesium in the case group was lower than those of the control group. There was no significant difference onserum potassium mean level between the case and control groups.
  
  
  CONCLUSIONS
  Deficiency of trace elements was correlated significantly with febrile convulsion, while further investigations on trace elements are required.
authors.affiliation: Birjand atherosclerosis and coronary artery research center, Birjand University of Medical Sciences (BUMS), Birjand, Iran.
authors.forename: Kokab
authors.initials: K
authors.lastname: Namakin
authors.affiliation: Birjand atherosclerosis and coronary artery research center, Department of pathology, Birjand University of Medical Sciences (BUMS), Birjand, Iran.
authors.forename: Mahmoud
authors.initials: M
authors.lastname: Zardast
authors.affiliation: Department of Social Medicine, Birjand University of Medical Sciences, Birjand, Iran.
authors.forename: Golamreza
authors.initials: G
authors.lastname: Sharifzadeh
authors.affiliation: Researcher, Birjand University of Medical Sciences, Birjand, Iran.
authors.forename: Toktam
authors.initials: T
authors.lastname: Bidar
authors.affiliation: Researcher, Birjand University of Medical Sciences, Birjand, Iran.
authors.forename: Samaneh
authors.initials: S
authors.lastname: Zargarian
keywords: Calcium; Children; Febrile convulsion; Magnesium; Sodium; Zinc