title: Accumulation of heavy metals and human health risk assessment via the consumption of freshwater fish Mastacembelus armatus inhabiting, thermal power plant effluent loaded canal.
abstract: Bioaccumulation of six heavy metals (Mn, Fe, Co, Ni, Cu, Zn) in the muscle of highly consumed fish species (Mastacembelus armatus) were measured using atomic absorption spectrometer. Fe (213.29 mg/kg dry weight) concentration was the most, followed by Zn (186.19 mg/kg dry weight), Ni (58.98 mg/kg dry weight), Cu (41.36 mg/kg dry weight), Co (9.06 mg/kg dry weight) and Mn (9.03 mg/kg dry weight). Estimated daily intake of heavy metals was calculated by mean fish consumption rate 19.5 × 10(-3) kg/day, on the basis of a calculation of the amount of fish consumed by adult individuals (male and female). The studied fish species pose non carcinogenic risk for Co and Ni [target hazard quotient (THQ) > 1] only. Hazard index (HI) was high. Carcinogenic risk (TR) posed by this fish for male and female was 3.43 × 10(-3) and 3.91 × 10(-3), respectively for Ni (the carcinogenic potency slope factor was available for Ni only). The study is an alert indicating that inhabitants who consume these fishes (particularly females) were at risk of Co and Ni toxicity. In India recommended guidelines have yet not been established for these heavy metals, which is essential for setting of toxicological standards.
authors.affiliation: Aquatic Toxicology Research Laboratory, Department of Zoology, Aligarh Muslim University, Aligarh, Uttar Pradesh 202002 India.
authors.forename: Mehjbeen
authors.initials: M
authors.lastname: Javed
authors.affiliation: Aquatic Toxicology Research Laboratory, Department of Zoology, Aligarh Muslim University, Aligarh, Uttar Pradesh 202002 India.
authors.forename: Nazura
authors.initials: N
authors.lastname: Usmani
keywords: Bioaccumulation; Carcinogenic risk; Dietary intake; Heavy metals; Human health risk; Target hazard quotient