title: Kindler syndrome: the case of two Iranian sisters.
abstract: Kindler syndrome is a rare autosomal recessive condition, characterized by multiple skin and mucosal abnormalities. Among the latter, esophageal involvement is an infrequent manifestation which may be completely asymptomatic or complicated by dysphagia. We report the case of two sisters presenting with cutaneous features and severe dysphagia. Endoscopic examination showed that the patients were affected by a rare condition named "esophageal web". Both patients showed significant improvement after balloon dilation. Clinicians should be aware of the potential complications of this disease, and the approach by balloon dilation should be considered as primary therapy in Kindler syndrome patients with esophageal web.
authors.affiliation: Department of General Surgery, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Saeed
authors.initials: S
authors.lastname: Kargar
authors.affiliation: Department of General Surgery, Shahid Sadoughi Hospital, Shahid Sadoughi University of Medical Sciences, Yazd, Iran - smshiryazdi@yahoo.com.
authors.forename: Seyed M
authors.initials: SM
authors.lastname: Shiryazdi
authors.affiliation: Department of Medical Genetics, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.|Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
authors.forename: Hossein
authors.initials: H
authors.lastname: Neamatzadeh
authors.affiliation: Islamic Azad University, Ashkzar Branch, Ashkzar, Yazd, Iran.
authors.forename: Vahid
authors.initials: V
authors.lastname: Ramazani
mesh_terms: D000328:Adult; D001768:Blister / Q000175:diagnosis* / Q000503:physiopathology; D003680:Deglutition Disorders / Q000209:etiology*; D004724:Endoscopy / Q000379:methods; D004820:Epidermolysis Bullosa / Q000175:diagnosis* / Q000503:physiopathology; D004947:Esophagus / Q000473:pathology; D005260:Female; D006801:Humans; D007492:Iran; D010510:Periodontal Diseases / Q000175:diagnosis* / Q000503:physiopathology; D010787:Photosensitivity Disorders / Q000175:diagnosis* / Q000503:physiopathology; D035781:Siblings; D055815:Young Adult