title: Synthesis and Antifungal Activities of Furoxan Derivatives Designed as Novel Fungicide.
abstract: Furoxan derivatives 3-11 were designed and synthesized as potential fungicides. Symmetrically substituted furoxan derivatives 3a-j were prepared by dimerization of the corresponding nitrile oxide generated from N-hydroxyliminoyl chloride 2 in situ. Further functional group modifications of aldehyde 4, a key intermediate, generated furoxan derivatives 5-11. The fungicidal activities of furoxan derivatives 3-11 were observed over a broad spectrum of plant fungi at 250 ppm.
authors.affiliation: a Department of Industrial Chemistry, Hongik University.
authors.forename: K J
authors.initials: KJ
authors.lastname: Hwang
authors.affiliation: a Department of Industrial Chemistry, Hongik University.
authors.forename: Y C
authors.initials: YC
authors.lastname: Park
authors.affiliation: b Department of Chemical Technology, Chonnam National University.
authors.forename: H J
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: c Korea Research Institute of Chemical Technology.
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
keywords: fungicidal activity; furazan N-oxide; furoxan; wheat leaf rust