title: Independent and core pathways in oncogenic KRAS signaling.
authors.affiliation: a Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Cancer and Inflammation Program , National Cancer Institute at Frederick , Frederick , MD , USA.|b Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine , Tel Aviv University , Tel Aviv , Israel.
authors.forename: Ruth
authors.initials: R
authors.lastname: Nussinov
authors.affiliation: a Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Cancer and Inflammation Program , National Cancer Institute at Frederick , Frederick , MD , USA.
authors.forename: Chung-Jung
authors.initials: CJ
authors.lastname: Tsai
authors.affiliation: a Basic Science Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Cancer and Inflammation Program , National Cancer Institute at Frederick , Frederick , MD , USA.
authors.forename: Hyunbum
authors.initials: H
authors.lastname: Jang
mesh_terms: D000818:Animals; D063646:Carcinogenesis / Q000235:genetics*; D006801:Humans; D009154:Mutation; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism; D016283:Proto-Oncogene Proteins p21(ras) / Q000502:physiology*; D015398:Signal Transduction
chemical_list: C117307:KRAS protein, human; D016283:Proto-Oncogene Proteins p21(ras)
keywords: K-Ras4B; KRAS; PI3K; Raf; Ras effectors; Ras isoforms; Ras pathways; cell cycle; lung cancer; pancreatic cancer