title: Neural activity in the medial parietal area V6A while grasping with or without visual feedback.
abstract: Recent works have reported that grasping movements are controlled not only by the dorsolateral visual stream, as generally thought, but also by the dorsomedial visual stream, and in particular by the medial posterior parietal area V6A. To date, the grasping activity of V6A neurons has been studied only in darkness. Here we studied the effect of visual feedback on grasp-related discharges of V6A neurons while the monkey was preparing and executing the grasping of a handle. We found that V6A grasping activity could be excited or inhibited by visual information. The neural population was divided into Visual, Motor, and Visuomotor cells. The majority of Visual and Visuomotor neurons did not respond to passive observation of the handle, suggesting that vision of action, rather than object vision, is the most effective factor. The present findings highlight the role of the dorsomedial visual stream in integrating visual and motor signals to monitor and correct grasping.
authors.affiliation: Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Piazza di Porta San Donato, 2, 40126 Bologna (Italy).
authors.forename: Rossella
authors.initials: R
authors.lastname: Breveglieri
authors.affiliation: Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Piazza di Porta San Donato, 2, 40126 Bologna (Italy).
authors.forename: Annalisa
authors.initials: A
authors.lastname: Bosco
authors.affiliation: Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Piazza di Porta San Donato, 2, 40126 Bologna (Italy).
authors.forename: Claudio
authors.initials: C
authors.lastname: Galletti
authors.affiliation: Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Piazza di Porta San Donato, 2, 40126 Bologna (Italy).
authors.forename: Lauretta
authors.initials: L
authors.lastname: Passarelli
authors.affiliation: Department of Pharmacy and Biotechnology (FaBiT), University of Bologna, Piazza di Porta San Donato, 2, 40126 Bologna (Italy).
authors.forename: Patrizia
authors.initials: P
authors.lastname: Fattori
mesh_terms: D000818:Animals; D001522:Behavior, Animal; D001931:Brain Mapping; D056228:Feedback, Sensory; D006225:Hand / Q000502:physiology; D018737:Hand Strength; D008252:Macaca fascicularis; D008297:Male; D009048:Motor Skills; D009068:Movement / Q000502:physiology*; D019579:Neocortex / Q000502:physiology; D009474:Neurons / Q000502:physiology*; D010296:Parietal Lobe / Q000502:physiology*; D010775:Photic Stimulation; D025341:Principal Component Analysis; D011597:Psychomotor Performance / Q000502:physiology*; D013028:Space Perception / Q000502:physiology; D014785:Vision, Ocular / Q000502:physiology*; D014796:Visual Perception / Q000502:physiology