title: Hemophagocytic Lymphohistiocytosis in a Young Child.
abstract: Hemophagocytic lymphohistiocytosis (HLH) is a multisystem disorder mediated by cytokine storm and is characterized by fever, pancytopenia and organomegaly coupled with laboratory features like hyperferritinemia, hypertriglyceridemia, hypofibrinogenemia and transaminitis. Etiology can be genetic or acquired such as infections, malignancy and autoimmune disorders. Diagnosis, identification of underlying etiology and management of HLH remain tough clinical puzzles to sort out for the managing physician. We report a clinico-pathological conference of a three-year-old boy who had such a presentation and succumbed during the hospital stay.
authors.affiliation: Departments of Pediatrics, *Histopathology and #Virology, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Correspondence to: Dr Anju Gupta, Additional Professor, Department of Pediatrics Postgraduate Institute of Medical Education and Research, Chandigarh, India. anjupgi@gmail.com.
authors.forename: Uma Nahar
authors.initials: UN
authors.lastname: Saikia
authors.forename: Anju
authors.initials: A
authors.lastname: Gupta
authors.forename: Pandiarajan
authors.initials: P
authors.lastname: Vignesh
authors.forename: Deepti
authors.initials: D
authors.lastname: Suri
authors.forename: Mini P
authors.initials: MP
authors.lastname: Singh
mesh_terms: D002675:Child, Preschool; D017809:Fatal Outcome; D006801:Humans; D008168:Lung / Q000473:pathology; D051359:Lymphohistiocytosis, Hemophagocytic; D008297:Male; D013270:Stomach / Q000473:pathology