title: [Laparoscopic reoperation for recurred antireflux surgery of gastroesophageal reflux disease].
abstract: OBJECTIVE
  To investigate the safety and effectiveness of laparoscopic reoperation for patients with gastroesophageal reflux disease (GERD) recurred form previous anti-reflux surgery.
  
  
  METHODS
  Totally 19 patients received laparoscopic reoperation for symptomatic and anatomic recurred GERD in Department of Gastroesophageal Reflux Disease, Rocket Force General Hospital from January 2008 to September 2015 were retrospectively analyzed. There were 12 male and 7 female patients. The average reoperation age was (48±14) years, the average duration of reoperation from original ones was (43±38) months. The patients underwent preoperative barium, endoscopy, manometry and 24-hour pH studies. Laparoscopic hiatal hernia repair plus fundoplication was carried out for reoperation. Gastroesophageal reflux related symptoms (reflux, heartburn, chest pain, chough, wheezing, chest tightness and globus sensation) before and after surgery were compared by a questionnaire. The patients' medication consumption, complications and satisfaction of the reoperation were investigated as well. The repeated measures analysis of variance was used for statistical comparison of data preoperatively and postoperatively.
  
  
  RESULTS
  No major complication and death occurred. Six cases (32%) had complications such as diarrhea, increased passing wind, flatulence, dysphagia and abdominal pain. The GERD related symptom score of reflux, heartburn, chest pain, chough, wheezing, chest tightness and globus sensation all significantly decreased (F: 25.0 to 56.7; P: 0.000 to 0.001) after the reoperation, with 68% good outcome of all the patients. After a follow-up of (33±22) months after reoperation, 1 case had partial recurrence at the 3(rd) month after reoperation. For all the patients, 12 cases felt very satisfied or satisfied with the reoperation.
  
  
  CONCLUSIONS
  Laparoscopic reoperation is generally effective with acceptable morbidity rates for patients with esophageal and extraesophageal symptoms recurred form previous hiatal repair and (or) fundoplication.
authors.affiliation: Department of Gastroesophageal Reflux Disease, Rocket Force General Hospital, Beijing 100088, China.
authors.forename: Z W
authors.initials: ZW
authors.lastname: Hu
authors.forename: J M
authors.initials: JM
authors.lastname: Wu
authors.forename: Z G
authors.initials: ZG
authors.lastname: Wang
authors.forename: F
authors.initials: F
authors.lastname: Wang
authors.forename: M P
authors.initials: MP
authors.lastname: Chen
authors.forename: Y Y
authors.initials: YY
authors.lastname: Dong
authors.forename: X L
authors.initials: XL
authors.lastname: Zhan
authors.forename: Y
authors.initials: Y
authors.lastname: Zhang
authors.forename: S S
authors.initials: SS
authors.lastname: Ma
authors.forename: C
authors.initials: C
authors.lastname: Zhang
authors.forename: C
authors.initials: C
authors.lastname: Yan
mesh_terms: D003680:Deglutition Disorders; D005260:Female; D018662:Fundoplication; D005764:Gastroesophageal Reflux; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008365:Manometry; D008875:Middle Aged; D012008:Recurrence; D012086:Reoperation; D012189:Retrospective Studies; D011795:Surveys and Questionnaires