title: [Future applications of mass spectrometry in microbiology].
abstract: MALDI-TOF (matrix-assisted laser desorption ionization time-of-flight) mass spectrometry (MS) has been vigorously introduced in many clinical microbiology laboratories for the rapid and accurate identification of bacteria and fungi. In fact, the implementation of this methodology can be considered a revolution in these laboratories. In addition to microbial identification, MALDI-TOF MS is being used for the detection of some mechanisms of antibiotic resistance and for the molecular typing of bacteria. A number of current and future applications that increase the versatility of this methodology may also be mentioned. Among these are its direct application on clinical samples, the detection of toxins or specific microbial antigens, and its application in the fields of virology and parasitology.
authors.affiliation: Servicio de Microbiología, Hospital Clínic, Instituto de Salud Global de Barcelona (ISGlobal), Centre de Recerca en Salut Internacional de Barcelona (CRESIB), Facultad de Medicina, Universidad de Barcelona, Barcelona, España. Electronic address: JVILA@clinic.ub.es.
authors.forename: Jordi
authors.initials: J
authors.lastname: Vila
authors.affiliation: Servicio de Microbiología, Hospital Clínic, Instituto de Salud Global de Barcelona (ISGlobal), Centre de Recerca en Salut Internacional de Barcelona (CRESIB), Facultad de Medicina, Universidad de Barcelona, Barcelona, España.
authors.forename: Yuliya
authors.initials: Y
authors.lastname: Zboromyrska
authors.affiliation: Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), CIBER de Enfermedades Respiratorias (CIBERES CB06/06/0058), Madrid, España.
authors.forename: Almudena
authors.initials: A
authors.lastname: Burillo
authors.affiliation: Servicio de Microbiología Clínica y Enfermedades Infecciosas, Hospital General Universitario Gregorio Marañón, Facultad de Medicina, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón (IiSGM), CIBER de Enfermedades Respiratorias (CIBERES CB06/06/0058), Madrid, España.
authors.forename: Emilio
authors.initials: E
authors.lastname: Bouza
mesh_terms: D001419:Bacteria / Q000302:isolation & purification; D001426:Bacterial Proteins / Q000032:analysis; D001427:Bacterial Toxins / Q000032:analysis; D015415:Biomarkers / Q000032:analysis; D001826:Body Fluids / Q000382:microbiology; D004352:Drug Resistance, Microbial; D005544:Forecasting; D005656:Fungal Proteins / Q000032:analysis; D005658:Fungi / Q000302:isolation & purification; D006801:Humans; D008828:Microbiological Techniques / Q000379:methods*; D010274:Parasitology / Q000379:methods*; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / Q000379:methods*
chemical_list: D001426:Bacterial Proteins; D001427:Bacterial Toxins; D015415:Biomarkers; D005656:Fungal Proteins
keywords: Antigens; Antígenos; Clinical samples; Espectrometría de masas; MALDI-TOF; Mass spectrometry; Muestras clínicas; Parasitology; Parasitología; Toxins; Toxínas; Virology; Virología