title: Innovations in American Society of Clinical Oncology Practice Guideline Development.
abstract: Since the beginning of its guidelines program in 1993, ASCO has continually sought ways to produce a greater number of guidelines while maintaining its commitment to using the rigorous development methods that minimize the biases that threaten the validity of practice recommendations. ASCO is implementing a range of guideline development and implementation innovations. In this article, we describe innovations that are designed to (1) integrate consideration of multiple chronic conditions into practice guidelines; (2) keep more of its guidelines current by applying evolving signals or (more) rapid, for-cause updating approaches; (3) increase the number of high-quality guidelines available to its membership through endorsement and adaptation of other groups' products; (4) improve coverage of its members' guideline needs through a new topic nomination process; and (5) enhance dissemination and promote implementation of ASCO guidelines in the oncology practice community through a network of volunteer ambassadors. We close with a summary of ASCO's plans to facilitate the integration of data from its rapid learning system, CancerLinQ, into ASCO guidelines and to develop tactics through which guideline recommendations can be embedded in clinicians' workflow in digital form. We highlight the challenges inherent in reconciling the need to provide clinicians with more interactive, point-of-care guidance with ASCO's abiding commitment to methodologic rigor in guideline development.
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA. mark.somerfield@asco.org.
authors.forename: Mark R
authors.initials: MR
authors.lastname: Somerfield
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Kari
authors.initials: K
authors.lastname: Bohlke
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: George P
authors.initials: GP
authors.lastname: Browman
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Neelima
authors.initials: N
authors.lastname: Denduluri
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Kaitlin
authors.initials: K
authors.lastname: Einhaus
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Daniel F
authors.initials: DF
authors.lastname: Hayes
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Alok A
authors.initials: AA
authors.lastname: Khorana
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Robert S
authors.initials: RS
authors.lastname: Miller
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Supriya G
authors.initials: SG
authors.lastname: Mohile
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Thomas K
authors.initials: TK
authors.lastname: Oliver
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Eduardo
authors.initials: E
authors.lastname: Ortiz
authors.affiliation: Mark R. Somerfield, Kari Bohlke, Kaitlin Einhaus, Robert S. Miller, Thomas K. Oliver, and Eduardo Ortiz, American Society of Clinical Oncology, Alexandria; Neelima Denduluri, U.S. Oncology Network, Virginia Cancer Specialists, Arlington, VA; George P. Browman, McMaster University, Hamilton, Ontario; University of British Columbia, Vancouver, British Columbia, Canada; Daniel F. Hayes, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Alok A. Khorana, Cleveland Clinic, Cleveland, OH; Supriya G. Mohile, University of Rochester, Rochester, NY; and Gary H. Lyman, Fred Hutchinson Cancer Research Center; University of Washington, Seattle, WA.
authors.forename: Gary H
authors.initials: GH
authors.lastname: Lyman
mesh_terms: D004059:Diffusion of Innovation; D019317:Evidence-Based Medicine / Q000592:standards; D019983:Guideline Adherence / Q000592:standards; D054625:Healthcare Disparities / Q000592:standards; D006801:Humans; D008495:Medical Oncology / Q000592:standards*; D000072103:Oncologists / Q000592:standards*; D017410:Practice Guidelines as Topic / Q000592:standards*; D010818:Practice Patterns, Physicians' / Q000592:standards*; D016730:Program Development; D058996:Quality Improvement / Q000592:standards; D019984:Quality Indicators, Health Care / Q000592:standards; D012955:Societies, Medical / Q000592:standards*; D013997:Time Factors; D014481:United States; D016526:Workload / Q000592:standards