title: CLAUSA Is a MYB Transcription Factor That Promotes Leaf Differentiation by Attenuating Cytokinin Signaling.
abstract: Leaf morphogenesis and differentiation are highly flexible processes, resulting in a large diversity of leaf forms. The development of compound leaves involves an extended morphogenesis stage compared with that of simple leaves, and the tomato (Solanum lycopersicum) mutant clausa (clau) exposes a potential for extended morphogenesis in tomato leaves. Here, we report that the CLAU gene encodes a MYB transcription factor that has evolved a unique role in compound-leaf species to promote an exit from the morphogenetic phase of tomato leaf development. We show that CLAU attenuates cytokinin signaling, and that clau plants have increased cytokinin sensitivity. The results suggest that flexible leaf patterning involves a coordinated interplay between transcription factors and hormones.
authors.affiliation: The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture and The Otto Warburg Minerva Center for Agricultural Biotechnology, Hebrew University, Rehovot 76100, Israel.
authors.forename: Maya
authors.initials: M
authors.lastname: Bar
authors.affiliation: The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture and The Otto Warburg Minerva Center for Agricultural Biotechnology, Hebrew University, Rehovot 76100, Israel.
authors.forename: Alon
authors.initials: A
authors.lastname: Israeli
authors.affiliation: The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture and The Otto Warburg Minerva Center for Agricultural Biotechnology, Hebrew University, Rehovot 76100, Israel.
authors.forename: Matan
authors.initials: M
authors.lastname: Levy
authors.affiliation: The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture and The Otto Warburg Minerva Center for Agricultural Biotechnology, Hebrew University, Rehovot 76100, Israel.
authors.forename: Hadas
authors.initials: H
authors.lastname: Ben Gera
authors.affiliation: Department of Plant Breeding and Genetics, Max Planck Institute for Plant Breeding Research, Cologne, Germany Institut Jean-Pierre Bourgin, INRA, AgroParisTech, CNRS, Université Paris-Saclay, 78026 Versailles Cedex, France.
authors.forename: José M
authors.initials: JM
authors.lastname: Jiménez-Gómez
authors.affiliation: Centre of the Region Haná for Biotechnological and Agricultural Research, Central Laboratories and Research Support Faculty of Science, Palacky University, Šlechtitelů 27, 78371 Olomouc, Czech Republic.
authors.forename: Stepan
authors.identifier: 0000-0002-7964-1147
authors.initials: S
authors.lastname: Kouril
authors.affiliation: Centre of the Region Haná for Biotechnological and Agricultural Research, Central Laboratories and Research Support Faculty of Science, Palacky University, Šlechtitelů 27, 78371 Olomouc, Czech Republic Centre of the Region Haná for Biotechnological and Agricultural Research, Department of Genetic Resources for Vegetables, Medicinal and Special Plants, Crop Research Institute, 78371 Olomouc, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Tarkowski
authors.affiliation: The Robert H. Smith Institute of Plant Sciences and Genetics in Agriculture and The Otto Warburg Minerva Center for Agricultural Biotechnology, Hebrew University, Rehovot 76100, Israel naomi.ori@mail.huji.ac.il.
authors.forename: Naomi
authors.initials: N
authors.lastname: Ori
mesh_terms: D003583:Cytokinins / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant / Q000235:genetics / Q000502:physiology; D018551:Solanum lycopersicum / Q000235:genetics / Q000378:metabolism*; D009154:Mutation / Q000235:genetics; D018515:Plant Leaves / Q000235:genetics / Q000378:metabolism*; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism*; D030821:Plants, Genetically Modified / Q000235:genetics / Q000378:metabolism; D015398:Signal Transduction / Q000235:genetics / Q000502:physiology; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism*
chemical_list: D003583:Cytokinins; D010940:Plant Proteins; D014157:Transcription Factors