title: Daily Pain, Physical Activity, and Home Fluid Intake in Pediatric Sickle Cell Disease.
abstract: This study examined the temporal relationship between physical activity, fluid intake, and daily pain in children with sickle cell disease (SCD) with frequent pain.
  
  
  
  A total of 30 African American children ( M age  =  13.9; 53% female; 76.3% type SS) who reported pain more than or equal to once every 2 weeks and their parents completed measures of pain and anxiety/depressive symptoms. Children then completed a daily pain diary and wore a physical activity Actiwatch for 14 days at home.
  
  
  
  Contrary to physiological theory-based hypotheses, lower physical activity was associated with greater pain during the same day and the next day. Less pain was associated with greater physical activity the next day. There was no relationship between self-reported home fluid intake and daily pain ( p 's  <  .05).
  
  
  
  Results lend support for a complex bidirectional relationship between physical activity and daily pain in pediatric SCD, and identify physical activity as a target for future research.
authors.affiliation: Division of Hematology-Oncology, Department of Pediatrics, University of Mississippi Medical Center, MS, USA.|Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, MS, USA.
authors.forename: Cynthia W
authors.initials: CW
authors.lastname: Karlson
authors.affiliation: Adherence Research Center, Johns Hopkins School of Medicine, Baltimore, MD, USA.
authors.forename: Anna M
authors.initials: AM
authors.lastname: Baker
authors.affiliation: Seattle Children's Research Institute, Center for Child Health, Behavior, and Development, M/S CW8-6, Seattle, WA, USA.
authors.forename: Maggie H
authors.initials: MH
authors.lastname: Bromberg
authors.affiliation: Division of Hematology-Oncology, Department of Pediatrics, University of Mississippi Medical Center, MS, USA.|Department of Psychiatry and Human Behavior, University of Mississippi Medical Center, MS, USA.
authors.forename: Thomas
authors.initials: T
authors.lastname: David Elkin
authors.affiliation: Division of Hematology-Oncology, Department of Pediatrics, University of Mississippi Medical Center, MS, USA.
authors.forename: Suvankar
authors.initials: S
authors.lastname: Majumdar
authors.affiliation: Seattle Children's Research Institute, Center for Child Health, Behavior, and Development, M/S CW8-6, Seattle, WA, USA.|Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
authors.forename: Tonya M
authors.initials: TM
authors.lastname: Palermo
mesh_terms: D000293:Adolescent; D001741:Black or African American; D000755:Anemia, Sickle Cell / Q000150:complications*; D004327:Drinking Behavior; D015444:Exercise; D005260:Female; D006801:Humans; D008297:Male; D010146:Pain / Q000150:complications*; D010147:Pain Measurement; D010290:Parents; D057566:Self Report
keywords: adolescents; children; hematology; pain; physical activity; rehydration