title: Human Immunodeficiency Virus/Acquired Immunodeficiency Syndrome in Older Adults.
abstract: Improved survival with combination antiretroviral therapy has led to a dramatic increase in the number of human immunodeficiency virus (HIV)-infected individuals 50 years of age or older such that by 2020 more than 50% of HIV-infected persons in the United States will be above this age. Recent studies confirm that antiretroviral therapy should be offered to all HIV-infected patients regardless of age, symptoms, CD4+ cell count, or HIV viral load. However, when compared with HIV-uninfected populations, even with suppression of measurable HIV replication, older individuals are at greater risk for cardiovascular disease, malignancies, liver disease, and other comorbidities.
authors.affiliation: Infectious Diseases Section, Department of Medicine, VA Greater Los Angeles Healthcare System, David Geffen School of Medicine at UCLA, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA.
authors.forename: Jake
authors.initials: J
authors.lastname: Scott
authors.affiliation: Infectious Diseases Section, Department of Medicine, VA Greater Los Angeles Healthcare System, David Geffen School of Medicine at UCLA, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA. Electronic address: Matthew.Goetz@va.gov.
authors.forename: Matthew Bidwell
authors.initials: MB
authors.lastname: Goetz
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000453:epidemiology*; D000328:Adult; D014943:Global Health; D006678:HIV; D015658:HIV Infections / Q000453:epidemiology*; D006801:Humans; D009017:Morbidity
keywords: Acquired immunodeficiency syndrome; Antiretroviral therapy; Epidemiology; Human immunodeficiency virus; Immunocompromised host