title: Correlation between ovarian morphology and biochemical and hormonal parameters in polycystic ovary syndrome.
abstract: OBJECTIVE
  To determine the biochemical and hormonal differences in polycystic ovary syndrome (PCOS) patients with and without polycystic ovary (PCO) morphology and to evaluate the outcomes resulting from those differences.
  
  
  METHODS
  The study included a total of 83 patients with PCOS; 43 of them had PCO morphology (Group-I) and 40 did not (Group-II). Serum LDL, HDL, total cholesterol, triglyceride (TG), total testosterone (T), follicle stimulating hormone (FSH), luteinizing hormone (LH), 17b-estradiol (E2), prolactin (PRL), thyroid stimulating hormone (TSH), sex hormone binding globulin (SHBG), glucose and insulin levels were determined. Homoeostatic model assessment insulin resistance (HOMA-IR) index was calculated.
  
  
  RESULTS
  The two groups were similar with respect to BMI. The systolic and diastolic blood pressure measurements of Group-I were significantly lower (p<0.01). Serum mean level of LH (p=0.026) and the mean LH/FSH (p=0.001) level of Group-I were significantly higher than Group-II. The total cholesterol and triglyceride levels of Group-I were significantly lower (p<0.05, p<0.01). The mean HOMA-IR level of Group-I was significantly lower than Group-II (p=0.004).
  
  
  CONCLUSIONS
  The group without PCO morphology had a higher risk than the other group in terms of increased insulin resistance, dyslipidemia and cardiovascular diseases due to effects of hyperandrogenism.
authors.affiliation: Dr. Cihan Inan, Department of Obstetrics and Gynecology, Kulu State Hospital, Konya, Turkey.
authors.forename: Cihan
authors.initials: C
authors.lastname: Inan
authors.affiliation: Dr. Cihan Karadag, Marmara University Pendik Training and Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.
authors.forename: Cihan
authors.initials: C
authors.lastname: Karadag
keywords: Hyperandrogenism; Insulin resistance; PCO morphology; PCOS; Total cholesterol