title: Design of iron oxide-based nanoparticles for MRI and magnetic hyperthermia.
abstract: Iron oxide nanoparticles are widely used for biological applications thanks to their outstanding balance between magnetic properties, surface-to-volume ratio suitable for efficient functionalization and proven biocompatibility. Their development for MRI or magnetic particle hyperthermia concentrates much of the attention as these nanomaterials are already used within the health system as contrast agents and heating mediators. As such, the constant improvement and development for better and more reliable materials is of key importance. On this basis, this review aims to cover the rational design of iron oxide nanoparticles to be used as MRI contrast agents or heating mediators in magnetic hyperthermia, and reviews the state of the art of their use as nanomedicine tools.
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Cristina
authors.initials: C
authors.lastname: Blanco-Andujar
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Aurelie
authors.initials: A
authors.lastname: Walter
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Geoffrey
authors.initials: G
authors.lastname: Cotin
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Catalina
authors.initials: C
authors.lastname: Bordeianu
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Damien
authors.initials: D
authors.lastname: Mertz
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Delphine
authors.initials: D
authors.lastname: Felder-Flesch
authors.affiliation: Institut de Physique et de Chimie des Matériaux de Strasbourg IPCMS, UMR CNRS-UdS 7504, 23 rue du Loess, BP 43, 67034 STRASBOURG cedex 2, France.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Begin-Colin
mesh_terms: D000818:Animals; D003287:Contrast Media / Q000737:chemistry* / Q000627:therapeutic use*; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D058185:Magnetite Nanoparticles / Q000737:chemistry* / Q000627:therapeutic use*
chemical_list: D003287:Contrast Media; D058185:Magnetite Nanoparticles
keywords: MRI; iron oxide; magnetic hyperthermia; nanoparticles