title: Intolerance to environmental chemicals and sounds in irritable bowel syndrome: Explained by central sensitization?
abstract: This study tested the hypotheses of irritable bowel syndrome showing (1) comorbidity with chemical and sound intolerance, other types of functionally somatic syndromes, and psychiatric disorders and (2) stronger than normal affective reactions to and behavioral disruptions from odorous/pungent chemicals and sounds in daily life. These hypotheses were tested by means of data from a large-scale population-based questionnaire study. The results showed comorbidity in irritable bowel syndrome with chemical and sound intolerance, fibromyalgia, migraine, post-traumatic stress disorder, generalized anxiety disorder, panic syndrome, and depression as well as strong reactions/disruptions from odorous/pungent chemicals and sounds in irritable bowel syndrome.
authors.affiliation: Umeå University, Sweden.
authors.forename: Linnea
authors.initials: L
authors.lastname: Ståhlberg
authors.affiliation: Umeå University, Sweden.
authors.forename: Eva
authors.initials: E
authors.lastname: Palmquist
authors.affiliation: Umeå University, Sweden.
authors.forename: Steven
authors.initials: S
authors.lastname: Nordin
mesh_terms: D000368:Aged; D059333:Central Nervous System Sensitization; D015897:Comorbidity; D004781:Environmental Exposure; D005260:Female; D006801:Humans; D043183:Irritable Bowel Syndrome / Q000523:psychology*; D008297:Male; D001523:Mental Disorders; D008875:Middle Aged; D013016:Sound; D013315:Stress, Psychological; D011795:Surveys and Questionnaires
keywords: adults; anxiety; depression; functional somatic syndrome; psychological distress; public health psychology