title: Ligand-controlled stereodivergent 1,3-dipolar cycloaddition of azomethine ylides with 3-methyl-4-nitro-5-styrylisoxazoles.
abstract: An unprecedented Ag(i)-catalyzed ligand-controlled stereodivergent 1,3-dipolar cycloaddition of azomethine ylides with 3-methyl-4-nitro-5-styrylisoxazoles has been developed to afford heterocycles bearing both methylisoxazole and pyrrolidine moieties. The endo- and exo-cycloadducts were obtained in good yields with excellent stereoselectivities, assisted by (t)Bu-Phosferrox and phosphoramidite as chiral ligands, respectively.
authors.affiliation: College of Chemistry and Molecular Sciences, Wuhan University, Wuhan 430072, China. cjwang@whu.edu.cn.
authors.forename: Kang
authors.initials: K
authors.lastname: Liu
authors.forename: Yong
authors.initials: Y
authors.lastname: Xiong
authors.forename: Zuo-Fei
authors.initials: ZF
authors.lastname: Wang
authors.forename: Hai-Yan
authors.initials: HY
authors.lastname: Tao
authors.forename: Chun-Jiang
authors.initials: CJ
authors.lastname: Wang