title: Water-compatible dummy molecularly imprinted resin prepared in aqueous solution for green miniaturized solid-phase extraction of plant growth regulators.
abstract: A water-compatible dummy molecularly imprinted resin (MIR) was synthesized in water using melamine, urea, and formaldehyde as hydrophilic monomers of co-polycondensation. A triblock copolymer (PEO-PPO-PEO, P123) was used as porogen to dredge the network structure of MIR, and N-(1-naphthyl) ethylenediamine dihydrochloride, which has similar shape and size to the target analytes, was the dummy template of molecular imprinting. The obtained MIR was used as the adsorbent in a green miniaturized solid-phase extraction (MIR⬜mini-SPE) of plant growth regulators, and there was no organic solvent used in the entire MIR⬜mini-SPE procedure. The calibration linearity of MIR⬜mini-SPE⬜HPLC method was obtained in a range 5⬜250ngmL(↙1) for IAA, IPA, IBA, and NAA with correlation coefficient (r) Ⱕ0.9998. Recoveries at three spike levels are in the range of 87.6⬜100.0% for coconut juice with relative standard deviations Ⱔ8.1%. The MIR⬜mini-SPE method possesses the advantages of environmental friendliness, simple operation, and high efficiency, so it is potential to apply the green pretreatment strategy to extraction of trace analytes in aqueous samples.
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding 071002, China.
authors.forename: Mingyu
authors.initials: M
authors.lastname: Wang
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding 071002, China.
authors.forename: Xiaochen
authors.initials: X
authors.lastname: Chang
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding 071002, China.
authors.forename: Xingyu
authors.initials: X
authors.lastname: Wu
authors.affiliation: Key Laboratory of Medicinal Chemistry and Molecular Diagnosis, Ministry of Education, Hebei University, Baoding 071002, China. Electronic address: yanhy@hbu.edu.cn.
authors.forename: Hongyuan
authors.initials: H
authors.lastname: Yan
authors.affiliation: Key Laboratory of Analytical Science and Technology of Hebei Province & Department of Biochemistry, Baoding University, Baoding 071002, China.
authors.forename: Fengxia
authors.initials: F
authors.lastname: Qiao
mesh_terms: D000327:Adsorption; D053000:Analytic Sample Preparation Methods / Q000379:methods; D002138:Calibration; D002851:Chromatography, High Pressure Liquid; D003059:Cocos / Q000737:chemistry; D005029:Ethylenediamines / Q000737:chemistry; D005557:Formaldehyde / Q000737:chemistry; D055772:Green Chemistry Technology / Q000379:methods*; D057927:Hydrophobic and Hydrophilic Interactions; D008904:Miniaturization; D054802:Molecular Imprinting; D010937:Plant Growth Regulators / Q000302:isolation & purification*; D011092:Polyethylene Glycols / Q000737:chemistry; D011409:Propylene Glycols / Q000737:chemistry; D012117:Resins, Synthetic / Q000138:chemical synthesis* / Q000737:chemistry; D052616:Solid Phase Extraction / Q000379:methods*; D012996:Solutions; D014227:Triazines / Q000737:chemistry; D014508:Urea / Q000737:chemistry; D014867:Water / Q000737:chemistry*
chemical_list: D005029:Ethylenediamines; C116176:PEO-PPO-PEO; D010937:Plant Growth Regulators; D011409:Propylene Glycols; D012117:Resins, Synthetic; D012996:Solutions; D014227:Triazines; C008588:N-(1-naphthyl)ethylenediamine; D014867:Water; D005557:Formaldehyde; D011092:Polyethylene Glycols; D014508:Urea; C011907:melamine
keywords: Green miniaturized solid-phase extraction; Molecularly imprinted resin; Plant growth regulators; Water-compatible materials