title: A comparative study of high-viscosity cement percutaneous vertebroplasty vs. low-viscosity cement percutaneous kyphoplasty for treatment of osteoporotic vertebral compression fractures.
abstract: The clinical effects of two different methods-high-viscosity cement percutaneous vertebroplasty (PVP) and low-viscosity cement percutaneous kyphoplasty (PKP) in the treatment of osteoporotic vertebral compression fractures (OVCFs) were investigated. From June 2010 to August 2013, 98 cases of OVCFs were included in our study. Forty-six patients underwent high-viscosity PVP and 52 patients underwent low-viscosity PKP. The occurrence of cement leakage was observed. Pain relief and functional activity were evaluated using the Visual Analog Scale (VAS) and Oswestry Disability Index (ODI), respectively. Restoration of the vertebral body height and angle of kyphosis were assessed by comparing preoperative and postoperative measurements of the anterior heights, middle heights and the kyphotic angle of the fractured vertebra. Nine out of the 54 vertebra bodies and 11 out of the 60 vertebra bodies were observed to have cement leakage in the high-viscosity PVP and low-viscosity PKP groups, respectively. The rate of cement leakage, correction of anterior vertebral height and kyphotic angles showed no significant differences between the two groups (P>0.05). Low-viscosity PKP had significant advantage in terms of the restoration of middle vertebral height as compared with the high-viscosity PVP (P<0.05). Both groups showed significant improvements in pain relief and functional capacity status after surgery (P<0.05). It was concluded that high-viscosity PVP and low-viscosity PKP have similar clinical effects in terms of the rate of cement leakage, restoration of the anterior vertebral body height, changes of kyphotic angles, functional activity, and pain relief. Low-viscosity PKP is better than high-viscosity PVP in restoring the height of the middle vertebra.
authors.affiliation: Department of Orthopedic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China.
authors.forename: Kai
authors.initials: K
authors.lastname: Sun
authors.affiliation: Department of Orthopedic Surgery, the Fifth Hospital of Wuhan, Wuhan, 430050, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Department of Orthopedic Surgery, Renmin Hospital of Wuhan University, Wuhan, 430060, China. penghaowhu@163.com.
authors.forename: Hao
authors.initials: H
authors.lastname: Peng
authors.affiliation: Department of Orthopedic Surgery, the Fifth Hospital of Wuhan, Wuhan, 430050, China.
authors.forename: Jun-Feng
authors.initials: JF
authors.lastname: Tan
authors.affiliation: Department of Orthopedic Surgery, the Fifth Hospital of Wuhan, Wuhan, 430050, China.
authors.forename: Mi
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Orthopedic Surgery, the Fifth Hospital of Wuhan, Wuhan, 430050, China.
authors.forename: Xian-Nian
authors.initials: XN
authors.lastname: Zheng
authors.affiliation: Department of Orthopedic Surgery, the Fifth Hospital of Wuhan, Wuhan, 430050, China.
authors.forename: Fang-Zhou
authors.initials: FZ
authors.lastname: Chen
authors.affiliation: Department of Orthopedic Surgery, the Fifth Hospital of Wuhan, Wuhan, 430050, China.
authors.forename: Ming-Hui
authors.initials: MH
authors.lastname: Li
mesh_terms: D000279:Administration, Cutaneous; D000368:Aged; D001843:Bone Cements / Q000737:chemistry / Q000627:therapeutic use*; D005260:Female; D005500:Follow-Up Studies; D050815:Fractures, Compression / Q000473:pathology / Q000534:rehabilitation / Q000601:surgery*; D006801:Humans; D058498:Kyphoplasty / Q000295:instrumentation / Q000379:methods*; D008297:Male; D008875:Middle Aged; D010024:Osteoporosis / Q000473:pathology / Q000534:rehabilitation / Q000601:surgery*; D010146:Pain / Q000175:diagnosis / Q000503:physiopathology; D010147:Pain Measurement; D020127:Recovery of Function / Q000502:physiology; D016103:Spinal Fractures / Q000473:pathology / Q000534:rehabilitation / Q000601:surgery*; D013131:Spine / Q000473:pathology / Q000601:surgery; D016896:Treatment Outcome; D014783:Viscosity; D064232:Visual Analog Scale
chemical_list: D001843:Bone Cements
keywords: high-viscosity cement percutaneous vertebroplasty; low-viscosity cement percutaneous kyphoplasty; osteoporotic vertebral compression fractures; treatment