title: Diagnosis and Management of Vertebral Compression Fractures.
abstract: Vertebral compression fractures (VCFs) are the most common complication of osteoporosis, affecting more than 700,000 Americans annually. Fracture risk increases with age, with four in 10 white women older than 50 years experiencing a hip, spine, or vertebral fracture in their lifetime. VCFs can lead to chronic pain, disfigurement, height loss, impaired activities of daily living, increased risk of pressure sores, pneumonia, and psychological distress. Patients with an acute VCF may report abrupt onset of back pain with position changes, coughing, sneezing, or lifting. Physical examination findings are often normal, but can demonstrate kyphosis and midline spine tenderness. More than two-thirds of patients are asymptomatic and diagnosed incidentally on plain radiography. Acute VCFs may be treated with analgesics such as acetaminophen, nonsteroidal anti-inflammatory drugs, narcotics, and calcitonin. Physicians must be mindful of medication adverse effects in older patients. Other conservative therapeutic options include limited bed rest, bracing, physical therapy, nerve root blocks, and epidural injections. Percutaneous vertebral augmentation, including vertebroplasty and kyphoplasty, is controversial, but can be considered in patients with inadequate pain relief with nonsurgical care or when persistent pain substantially affects quality of life. Family physicians can help prevent vertebral fractures through management of risk factors and the treatment of osteoporosis.
authors.affiliation: David Grant Medical Center Family Medicine Residency Program, Travis Air Force Base, CA, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: McCarthy
authors.affiliation: David Grant Medical Center Family Medicine Residency Program, Travis Air Force Base, CA, USA.
authors.forename: Amy
authors.initials: A
authors.lastname: Davis
mesh_terms: D000700:Analgesics / Q000627:therapeutic use*; D050071:Bone Density Conservation Agents / Q000627:therapeutic use*; D002116:Calcitonin / Q000627:therapeutic use; D000072700:Conservative Treatment; D050815:Fractures, Compression / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000628:therapy*; D006801:Humans; D058498:Kyphoplasty; D009407:Nerve Block; D010024:Osteoporosis / Q000188:drug therapy*; D058866:Osteoporotic Fractures / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000628:therapy*; D059408:Pain Management; D026741:Physical Therapy Modalities; D011859:Radiography; D016103:Spinal Fractures / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000628:therapy*; D054854:Vertebroplasty
chemical_list: D000700:Analgesics; D050071:Bone Density Conservation Agents; D002116:Calcitonin