title: Noncoding RNAs in Cancer Immunology.
abstract: Cancer immunology is the study of interaction between cancer cells and immune system by the application of immunology principle and theory. With the recent approval of several new drugs targeting immune checkpoints in cancer, cancer immunology has become a very attractive field of research and is thought to be the new hope to conquer cancer. This chapter introduces the aberrant expression and function of noncoding RNAs, mainly microRNAs and long noncoding RNAs, in tumor-infiltrating immune cells, and their significance in tumor immunity. It also illustrates how noncoding RNAs are shuttled between tumor cells and immune cells in tumor microenvironments via exosomes or other microvesicles to modulate tumor immunity.
authors.affiliation: Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107, Yanjiang West Road, Guangzhou, 510120, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: Sun Yat-sen Memorial Hospital, Sun Yat-sen University, 107, Yanjiang West Road, Guangzhou, 510120, China. victorlq@hotmail.com.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
mesh_terms: D055354:Exosomes / Q000235:genetics / Q000276:immunology; D015972:Gene Expression Regulation, Neoplastic / Q000235:genetics / Q000276:immunology; D006801:Humans; D016246:Lymphocytes, Tumor-Infiltrating / Q000276:immunology* / Q000473:pathology; D035683:MicroRNAs / Q000235:genetics* / Q000276:immunology; D009369:Neoplasms / Q000235:genetics* / Q000276:immunology; D062085:RNA, Long Noncoding / Q000235:genetics* / Q000276:immunology; D059016:Tumor Microenvironment / Q000235:genetics / Q000276:immunology
chemical_list: D035683:MicroRNAs; D062085:RNA, Long Noncoding
keywords: Cancer immunology; Long noncoding RNAs; MicroRNAs; Noncoding RNAs