title: Randomized controlled trial of a 12-month computerized mindfulness-based intervention for obese patients with binge eating disorder: The MindOb study protocol.
abstract: Mindfulness-based interventions for healthy behaviors such as exercise and dietary modifications have aroused growing interest. This study aims to test the effectiveness of a mindfulness-based intervention for the reduction of impulsive eating and the improvement of motivation to exercise among obese individuals.
  
  
  
  One-hundred and twenty obese outpatients, aged 18 to 65years, diagnosed with a binge eating disorder, will be randomly assigned to one of the three following groups: mindfulness practice, sham meditation, or treatment as usual control. The tested intervention consists of a 1-year computerized mindfulness-based program. Mindfulness sessions are audio recordings that the patients are asked to listen to, 10min every day. Self-reported questionnaires measuring impulsive eating, motivation to exercise, physical activity level, mood, and mindfulness skills are filled in at baseline, 1, 6, and 12months. Physical activity, calories consumption, and biomarkers are measured with more objective measurement tools at baseline, 6months and 12months.
  
  
  
  Mindfulness, as both a de-automation element and as a moderator of motivation to exercise, can lead to the reduction of impulsive eating and also to an increase in levels of physical activity. These effects could cause weight loss in obese patients suffering from binge eating disorder.
  
  
  
  clinicaltrials.gov: NCT02571387.
authors.affiliation: Laboratoire de Psychopathologie et Processus de Santé (EA 4057), Université Paris Descartes, Sorbonne Paris Cité, France; Unité de Nutrition, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, France. Electronic address: alexis.ruffault@parisdescartes.fr.
authors.forename: Alexis
authors.initials: A
authors.lastname: Ruffault
authors.affiliation: Unité de Nutrition, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, France.
authors.forename: Claire
authors.initials: C
authors.lastname: Carette
authors.affiliation: Unité de Nutrition, Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris, France; Unité de Nutrition, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, France.
authors.forename: Kàtia
authors.initials: K
authors.lastname: Lurbe I Puerto
authors.affiliation: Mindeval, Canada.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Juge
authors.affiliation: Unité de Recherche Clinique, Hôpital Ambroise Paré, Assistance Publique-Hôpitaux de Paris, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Beauchet
authors.affiliation: Service de Biochimie Endocrinienne et Oncologique, HU Pitié-Salpêtrière-Charles Foix, Assistance Publique-Hôpitaux de Paris, France.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Benoliel
authors.affiliation: Service de Biochimie Endocrinienne et Oncologique, HU Pitié-Salpêtrière-Charles Foix, Assistance Publique-Hôpitaux de Paris, France.
authors.forename: Jean-Marc
authors.initials: JM
authors.lastname: Lacorte
authors.affiliation: Université Paris Ouest Nanterre la Défense, France.
authors.forename: Jean F
authors.initials: JF
authors.lastname: Fournier
authors.affiliation: Unité de Nutrition, Hôpital Européen Georges-Pompidou, Assistance Publique-Hôpitaux de Paris, France; Université Paris Descartes, France; INSERM UMS 011, Population-Based Cohorts, France.
authors.forename: Sébastien
authors.initials: S
authors.lastname: Czernichow
authors.affiliation: Laboratoire de Psychopathologie et Processus de Santé (EA 4057), Université Paris Descartes, Sorbonne Paris Cité, France.
authors.forename: Cécile
authors.initials: C
authors.lastname: Flahault
mesh_terms: D056912:Binge-Eating Disorder / Q000150:complications / Q000628:therapy*; D015444:Exercise; D006801:Humans; D007175:Impulsive Behavior; D019122:Meditation; D064866:Mindfulness / Q000379:methods*; D009042:Motivation; D009765:Obesity / Q000150:complications / Q000628:therapy*; D013813:Therapy, Computer-Assisted
keywords: Impulsive eating; Internet-based intervention; Mindfulness; Obesity; Physical activity