title: Cardiohepatic Interactions: Implications for Management in Advanced Heart Failure.
abstract: Liver disease is a common sequela of heart failure and can range from mild reversible liver injury to hepatic fibrosis and, in its most severe form, cardiac cirrhosis. Hepatic fibrosis and cirrhosis due to chronic heart failure have important implications for prognosis, medication management, mechanical circulatory support, and heart transplantation. This article reviews the current understanding of liver disease in heart failure and provides a framework for approaching liver disease in the advanced heart failure population.
authors.affiliation: Knight Cardiovascular Institute, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, UHN 62, Portland, OR 97239, USA.
authors.forename: Akshay
authors.initials: A
authors.lastname: Pendyal
authors.affiliation: Knight Cardiovascular Institute, Oregon Health and Science University, 3181 Southwest Sam Jackson Park Road, UHN 62, Portland, OR 97239, USA. Electronic address: gelowj@ohsu.edu.
authors.forename: Jill M
authors.initials: JM
authors.lastname: Gelow
mesh_terms: D015897:Comorbidity; D019468:Disease Management; D006333:Heart Failure / Q000503:physiopathology / Q000628:therapy*; D006801:Humans; D008099:Liver / Q000503:physiopathology; D008107:Liver Diseases / Q000175:diagnosis* / Q000503:physiopathology; D018802:Patient-Centered Care; D011379:Prognosis
keywords: Advanced heart failure; Chronic heart failure; Cirrhosis; Heart transplantation; Hepatic fibrosis; Hepatitis C; Liver disease; Mechanical circulatory support