title: Thrombocytopenia and Postpartum Hemorrhage in a Woman with Chromosome 22q11.2 Deletion Syndrome.
abstract: Chromosome 22q11.2 deletion syndrome, also known as DiGeorge or velocardiofacial syndrome, is associated with a wide spectrum of phenotypic features. It is known to be associated with severe macrothrombocytopenia. Postpartum hemorrhage is a leading cause of maternal morbidity and mortality globally. Chromosome 22q11.2 deletion syndrome is rare cause of thrombocytopenia that can be a significant risk factor for life-threatening postpartum hemorrhage. We report a case of postpartum hemorrhage in a woman with 22q11.2 deletion syndrome causing severe macrothrombocytopenia.
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Long Island Jewish Medical Center, New Hyde Park, NY 11042, USA.
authors.forename: Sarah L
authors.identifier: 0000-0002-8771-0675
authors.initials: SL
authors.lastname: Pachtman
authors.affiliation: Division of Hematology-Oncology, Department of Internal Medicine, Hofstra Northwell School of Medicine, Long Island Jewish Medical Center, New Hyde Park, NY 11042, USA.
authors.forename: Kathy
authors.initials: K
authors.lastname: Deng
authors.affiliation: Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Hofstra Northwell School of Medicine, Long Island Jewish Medical Center, New Hyde Park, NY 11042, USA.
authors.forename: Deepak
authors.initials: D
authors.lastname: Nanda