title: [Efficient evaluation of standardized specific immunotherapy in personalized maintenance phase to patients of allergic rhinitis].
abstract: OBJECTIVE
  To explore the efficacy of individualized subcutaneous immunotherapy (SCIT) in allergic rhinitis(AR) maintain phase.
  
  
  METHODS
  Compare nasal symptom scores (VAS) and special disease scale--nasal conjunctivitis quality of life questionnaire(RQLQ) score after 3 years treatment to evaluate the therapeutic effect of each group and the level of improving patients quality of life. Take patients' blood to detect the serum level of IL-10 by enzyme linked immunosorbent test (enzyme linked immunosorbent assay).
  
  
  RESULTS
  After 3 years treatment, there was no difference of VAS between the conventional SCIT group and the individualized SCIT group. ELISA results showed that the level of IL-10 was significantly higher in the drug symptomatic treatment group than that in the healthy group, the levels of IL-10 were significantly lower in the conventional SCIT group and the individualized SCIT group than that in the healthy group, but there was no difference between the conventional SCIT and the individualized SCIT group.
  
  
  CONCLUSIONS
  After 3 years treatment, there was no difference between conventional and individualized SCIT groups. But the efficacy of the conventional and individualized SCIT groups were significantly better than that in the drug symptomatic treatment group.
authors.forename: Yuqin
authors.initials: Y
authors.lastname: Deng
authors.forename: Yaqi
authors.initials: Y
authors.lastname: Yang
authors.forename: Shenglan
authors.initials: S
authors.lastname: Li
authors.forename: Yan
authors.initials: Y
authors.lastname: Yan
authors.forename: Yu
authors.initials: Y
authors.lastname: Xu
authors.forename: Yinghong
authors.initials: Y
authors.lastname: Zheng
authors.forename: Ailing
authors.initials: A
authors.lastname: Deng
authors.forename: Wanyi
authors.initials: W
authors.lastname: Chen
authors.forename: Zezhang
authors.initials: Z
authors.lastname: Tao
mesh_terms: D003888:Desensitization, Immunologic; D004797:Enzyme-Linked Immunosorbent Assay; D006801:Humans; D007279:Injections, Subcutaneous; D016753:Interleukin-10 / Q000097:blood; D057285:Precision Medicine; D011788:Quality of Life; D065631:Rhinitis, Allergic / Q000188:drug therapy*; D011795:Surveys and Questionnaires
chemical_list: C508609:IL10 protein, human; D016753:Interleukin-10