title: Manauealide C and Anhydrodebromoaplysiatoxin, Toxic Constituents of the Hawaiian Red Alga, Gracilaria coronopifolia.
abstract: Manauealide C (1) and anhydrodebromoaplysiatoxin (4), toxic constituents of the Hawaiian red alga, Gracilaria coronopifolia which has been concerned with food poisoning cases, were studied. The absolute structure of manauealide C was determined as 1 by chemical conversion and spectroscopic methods. The first complete assignment of (13)C chemical shifts for anhydrodebromoaplysiatoxin (4) was established. The biological activity of 4 was also investigated.
authors.affiliation: a Suntory Institute for Bioorganic Research.
authors.forename: H
authors.initials: H
authors.lastname: Nagai
authors.affiliation: a Suntory Institute for Bioorganic Research.
authors.forename: Y
authors.initials: Y
authors.lastname: Kan
authors.affiliation: a Suntory Institute for Bioorganic Research.
authors.forename: T
authors.initials: T
authors.lastname: Fujita
authors.affiliation: b John A. Burns School of Medicine, University of Hawaii at Manoa.
authors.forename: B
authors.initials: B
authors.lastname: Sakamoto
authors.affiliation: b John A. Burns School of Medicine, University of Hawaii at Manoa.
authors.forename: Y
authors.initials: Y
authors.lastname: Hokama
keywords: Gracilaria coronopifolia; absolute configuration; anhydrodebromoaplysiatoxin; manauealide C; marine algal toxin