title: Glycosylation Reaction of Thioglycosides by Using Hypervalent Iodine(III) Reagent as an Excellent Promoter.
abstract: Thioglycosides are available donors in glycosylation due to the stability of the anomeric C-S bond under general reaction conditions of protection and deprotection, and offer orthogonality in their activation. We report now that the hypervalent iodine effectively induced glycosylation reaction of thioglycosides with various alcohols. This method features a high efficiency, completion in a short time, and proceeding under very mild conditions.
authors.affiliation: Research Organization of Science and Technology, Ritsumeikan University.
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Kajimoto
authors.forename: Koji
authors.initials: K
authors.lastname: Morimoto
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Ogawa
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Dohi
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Kita
mesh_terms: D000438:Alcohols / Q000737:chemistry; D006031:Glycosylation; D007202:Indicators and Reagents; D007455:Iodine / Q000737:chemistry*; D007462:Iodobenzenes / Q000737:chemistry*; D015394:Molecular Structure; D013865:Thioglycosides / Q000737:chemistry*; D014269:Trifluoroacetic Acid / Q000737:chemistry*
chemical_list: D000438:Alcohols; D007202:Indicators and Reagents; D007462:Iodobenzenes; D013865:Thioglycosides; C517666:phenyliodine(III) bis(trifluoroacetate); D007455:Iodine; D014269:Trifluoroacetic Acid