title: [Paratracheal lymph node with suspicion of carcinoma].
abstract: Three paratracheal lymph nodes of a 20-year-old patient were submitted for examination, of which one showed numerous thyrocytes with large void nuclei and was suspected of being metastatic papillary thyroid carcinoma. The simultaneously resected thyroid gland, which was subsequently submitted showed findings consistent with Hashimoto's autoimmune thyroiditis (AIT). In the context of the resected goiter tissue, the suspected lymph node metastasis was identified as a hyperplastic ectopic (so-called parasitic) goiter nodule with thyrocytic changes typically seen in Hashimoto's AIT, such as oxyphilic cell alterations and a high plasma cell content. The re-examination of the suspicious lymph node revealed complete lack of a marginal sinus, thus excluding the diagnosis of a lymph node as well as the diagnosis of thyroid carcinoma metastasis.
authors.affiliation: Dr. Senckenbergisches Institut für Pathologie, Klinikum der J. W. Goethe Universität Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Meister
authors.affiliation: Endokrine Chirurgie, Bürgerhospital, Nibelungenallee, Frankfurt am Main, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Vorländer
authors.affiliation: Dr. Senckenbergisches Institut für Pathologie, Klinikum der J. W. Goethe Universität Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland. s.hartmann@em.uni-frankfurt.de.
authors.forename: S
authors.initials: S
authors.lastname: Hartmann
authors.affiliation: Dr. Senckenbergisches Institut für Pathologie, Klinikum der J. W. Goethe Universität Frankfurt am Main, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland.
authors.forename: M-L
authors.initials: ML
authors.lastname: Hansmann
mesh_terms: D002467:Cell Nucleus / Q000473:pathology; D002828:Choristoma / Q000473:pathology; D003937:Diagnosis, Differential; D006042:Goiter; D050031:Hashimoto Disease / Q000473:pathology; D006801:Humans; D008198:Lymph Nodes / Q000473:pathology*; D008207:Lymphatic Metastasis / Q000473:pathology*; D008297:Male; D024862:Oxyphil Cells / Q000473:pathology; D010950:Plasma Cells / Q000473:pathology; D000072637:Thyroid Epithelial Cells / Q000473:pathology; D013961:Thyroid Gland; D013965:Thyroidectomy; D014133:Tracheal Diseases / Q000175:diagnosis; D014134:Tracheal Neoplasms / Q000473:pathology*; D055815:Young Adult
keywords: Ectopic (parasitic) goiter; Hashimoto’s autoimmune thyroiditis; High plasma cell content; Hürthle cell; Lymph node metastasis