title: Acute Alcoholic Hepatitis: Therapy.
abstract: Alcoholic hepatitis (AH) causes great morbidity and mortality in the United States and throughout the world. Advances in therapy have proven difficult. In part, this reflects challenges in diagnosis, including the distinction between AH and acute-on-chronic liver failure. Liver biopsy is the best method to clarify the cause in circumstances whereby conflicting clinical data confound the diagnosis. All treatment of AH begins with abstinence from alcohol. All patients with AH should be given sufficient nutrition. Prednisolone has become the principal agent for treating patients with severe AH.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, WI 53705-2281, USA.
authors.forename: Paulina K
authors.initials: PK
authors.lastname: Phillips
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Medicine, University of Wisconsin School of Medicine and Public Health, 1685 Highland Avenue, Madison, WI 53705-2281, USA. Electronic address: mrl@medicine.wisc.edu.
authors.forename: Michael R
authors.initials: MR
authors.lastname: Lucey
mesh_terms: D000208:Acute Disease; D064829:Alcohol Abstinence; D000975:Antioxidants / Q000627:therapeutic use; D005938:Glucocorticoids / Q000627:therapeutic use; D006519:Hepatitis, Alcoholic / Q000175:diagnosis / Q000628:therapy*; D006801:Humans; D016031:Liver Transplantation; D010431:Pentoxifylline / Q000627:therapeutic use; D011239:Prednisolone / Q000627:therapeutic use
chemical_list: D000975:Antioxidants; D005938:Glucocorticoids; D011239:Prednisolone; D010431:Pentoxifylline
keywords: Anti-TNFα; Antioxidants; Corticosteroids; Liver transplantation; Nutrition; Palliative care; Pentoxifylline; Prednisolone