title: Targeted Nanotheranostics for Future Personalized Medicine: Recent Progress in Cancer Therapy.
abstract: Recently, many theranostic nanomaterials have been developed by integrating therapeutic and diagnostic agents in a single regimen. Real-time visualization of nano drug carrier biodistributions, drug release processes and therapeutic responses can provide critical information needed for dynamically optimizing treatment operations in a personalized manner in real time. This review highlights recent progresses in the development of multifunctional nanoparticles possessing both therapeutic and imaging functionalities for cancer therapy. The advantages of using nanoparticle platforms are discussed. Examples demonstrating various combinations of imaging and therapeutic modalities are highlighted.
authors.affiliation: 1. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
authors.forename: Sung Duk
authors.initials: SD
authors.lastname: Jo
authors.affiliation: 1. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
authors.forename: Sook Hee
authors.initials: SH
authors.lastname: Ku
authors.affiliation: 1. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.; 2. School of Chemical Engineering, and Purdue University Center for Cancer Research, Purdue University, West Lafayette, IN 47907, USA.
authors.forename: You-Yeon
authors.initials: YY
authors.lastname: Won
authors.affiliation: 1. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.
authors.forename: Sun Hwa
authors.initials: SH
authors.lastname: Kim
authors.affiliation: 1. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), 5 Hwarang-ro 14-gil, Seongbuk-gu, Seoul 02792, Republic of Korea.; 3. KU-KIST School, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul02841, Republic of Korea.
authors.forename: Ick Chan
authors.initials: IC
authors.lastname: Kwon
mesh_terms: D000818:Animals; D006801:Humans; D058990:Molecular Targeted Therapy / Q000379:methods* / Q000639:trends; D009369:Neoplasms / Q000175:diagnosis* / Q000628:therapy*; D057285:Precision Medicine / Q000379:methods* / Q000639:trends; D000068936:Theranostic Nanomedicine / Q000379:methods* / Q000639:trends
keywords: Cancer therapy.; Nanotheranostics; Personalized medicine