title: First report of monomicrobial Candida parapsilosis necrotizing fasciitis.
abstract: Candida parapsilosis is an emerging pathogen worldwide. It commonly causes soft tissue infection; however, to our knowledge there has been no previous report of monomicrobial necrotizing soft tissue infection (NSTI) secondary to C. parapsilosis. We report the first case of NSTI caused by C. parapsilosis in an immunocompromised renal transplant patient, with the diagnosis proven both histologically and microbiologically. Our patient required aggressive surgical intervention and antifungal therapy, with postoperative survival at 90 days.
authors.affiliation: Department of Infectious Diseases, Princess Alexandra Hospital, Queensland Health, Woolloongabba, Queensland, Australia. ian.gassiep@gmail.com.|School of Medicine, University of Queensland, Brisbane, Queensland, Australia. ian.gassiep@gmail.com.
authors.forename: I
authors.initials: I
authors.lastname: Gassiep
authors.affiliation: Department of Infectious Diseases, Princess Alexandra Hospital, Queensland Health, Woolloongabba, Queensland, Australia.
authors.forename: J
authors.initials: J
authors.lastname: Douglas
authors.affiliation: Department of Infectious Diseases, Princess Alexandra Hospital, Queensland Health, Woolloongabba, Queensland, Australia.|School of Medicine, University of Queensland, Brisbane, Queensland, Australia.
authors.forename: E G
authors.initials: EG
authors.lastname: Playford
mesh_terms: D000671:Amputation, Surgical; D000935:Antifungal Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D002175:Candida / Q000302:isolation & purification / Q000472:pathogenicity*; D002179:Candidiasis, Cutaneous / Q000382:microbiology*; D000077336:Caspofungin; D054714:Echinocandins / Q000008:administration & dosage / Q000627:therapeutic use; D019115:Fasciitis, Necrotizing / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D015725:Fluconazole / Q000008:administration & dosage / Q000627:therapeutic use; D006801:Humans; D006977:Hypertension, Renal / Q000601:surgery; D016867:Immunocompromised Host; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects*; D007866:Leg / Q000601:surgery; D055666:Lipopeptides / Q000008:administration & dosage / Q000627:therapeutic use; D008297:Male; D008875:Middle Aged; D009393:Nephritis / Q000601:surgery
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D055666:Lipopeptides; D015725:Fluconazole; D000077336:Caspofungin
keywords: 
  Candida parapsilosis
  ; immunosuppression; necrotizing fasciitis; necrotizing soft tissue infection; transplant