title: Optic Nerve Parameters in Obese Children as Measured by Spectral Domain Optical Coherence Tomography.
abstract: OBJECTIVE
  To investigate whether an association exists between obesity and optic nerve parameters.
  
  
  METHODS
  This was a prospective comparative study including 125 eyes of 63 obese and 122 eyes of 62 healthy pediatric subjects. Optic nerve measurements were performed using the Cirrus spectral domain optical coherence tomograph (SD-OCT).
  
  
  RESULTS
  The disc area, cup volume, mean and vertical C/D ratio, inferior and temporal RNFL thickness values were significantly higher in the control group than the obese group; however, age, sex, mean, superior and nasal RNFL thickness and rim area measurements were not statistically significantly different between the two groups. Age was significantly negatively correlated with temporal RNFL thickness in the obese group. Girls had significantly higher rim area, mean and superior RNFL thickness, and lower cup volume and vertical C/D ratio than boys in the obese group.
  
  
  CONCLUSIONS
  These results could be helpful in the diagnosis and follow-up of obese children.
authors.affiliation: a Ankara Numune Training and Research Hospital , Ankara , Turkey.
authors.forename: Semra
authors.initials: S
authors.lastname: Koca
authors.affiliation: b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey.
authors.forename: Melikşah
authors.initials: M
authors.lastname: Keskin
authors.affiliation: a Ankara Numune Training and Research Hospital , Ankara , Turkey.
authors.forename: M Sinan
authors.initials: MS
authors.lastname: Saricaoglu
authors.affiliation: c School of Medicine , Hacettepe University , Ankara , Turkey.
authors.forename: Serkan Bilge
authors.initials: SB
authors.lastname: Koca
authors.affiliation: d Kayseri Education and Research Hospital , Kayseri , Turkey.
authors.forename: Necati
authors.initials: N
authors.lastname: Duru
authors.affiliation: a Ankara Numune Training and Research Hospital , Ankara , Turkey.
authors.forename: Mualla
authors.initials: M
authors.lastname: Şahin Hamurcu
authors.affiliation: b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey.
authors.forename: Nursel
authors.initials: N
authors.lastname: Şahin Muratoğlu
authors.affiliation: b Dr. Sami Ulus Training and Research Hospital of Women's and Children's Health and Diseases , Ankara , Turkey.
authors.forename: Zehra
authors.initials: Z
authors.lastname: Aycan
mesh_terms: D000293:Adolescent; D016022:Case-Control Studies; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D009412:Nerve Fibers / Q000473:pathology; D009765:Obesity / Q000473:pathology*; D009898:Optic Disk / Q000473:pathology; D009900:Optic Nerve / Q000473:pathology*; D011446:Prospective Studies; D012165:Retinal Ganglion Cells / Q000473:pathology; D012737:Sex Factors; D041623:Tomography, Optical Coherence / Q000379:methods
keywords: Obesity; optical coherence tomography; pediatric; retinal nerve fiber; spectral domain