title: Detection of phenazepam in illicitly manufactured Erimin 5 tablets.
abstract: A validated ultra-high-performance liquid chromatographic (UHPLC) method was used to determine the phenazepam dosage in clandestinely produced Erimin 5 tablets. Tablets from five different seizures submitted to the laboratory in 2013 were found to have a dosage of about 2.4 milligrams. The measurement uncertainty of the assay was estimated to be 3.2 % (relative) at a coverage factor of k=2. As an adjunct study the dyes in the tablets from several seizures were determined by thin-layer chromatography (TLC) for future comparative studies.
authors.affiliation: Illicit Drugs Laboratory, Illicit Drugs Division, Applied Sciences Group, Health Sciences Authority, Singapore.
authors.forename: Wendy J L
authors.initials: WJ
authors.lastname: Lim
authors.affiliation: Illicit Drugs Laboratory, Illicit Drugs Division, Applied Sciences Group, Health Sciences Authority, Singapore.
authors.forename: Angeline T W
authors.initials: AT
authors.lastname: Yap
authors.affiliation: Illicit Drugs Laboratory, Illicit Drugs Division, Applied Sciences Group, Health Sciences Authority, Singapore.
authors.forename: Merula
authors.initials: M
authors.lastname: Mangudi
authors.affiliation: Illicit Drugs Laboratory, Illicit Drugs Division, Applied Sciences Group, Health Sciences Authority, Singapore.
authors.forename: H B
authors.initials: HB
authors.lastname: Koh
authors.affiliation: Illicit Drugs Laboratory, Illicit Drugs Division, Applied Sciences Group, Health Sciences Authority, Singapore.
authors.forename: Angeline S Y
authors.initials: AS
authors.lastname: Tang
authors.affiliation: Illicit Drugs Laboratory, Illicit Drugs Division, Applied Sciences Group, Health Sciences Authority, Singapore.
authors.forename: K B
authors.initials: KB
authors.lastname: Chan
mesh_terms: D000927:Anticonvulsants / Q000032:analysis*; D001569:Benzodiazepines / Q000032:analysis*; D002851:Chromatography, High Pressure Liquid / Q000379:methods*; D008401:Gas Chromatography-Mass Spectrometry / Q000379:methods; D013287:Illicit Drugs / Q000032:analysis*; D057230:Limit of Detection; D013055:Spectrophotometry, Infrared / Q000379:methods; D013607:Tablets / Q000737:chemistry
chemical_list: D000927:Anticonvulsants; D013287:Illicit Drugs; D013607:Tablets; D001569:Benzodiazepines; C017928:phenazepam