title: Properties of a monopivot centrifugal blood pump manufactured by 3D printing.
abstract: An impeller the same geometry as the impeller of a commercial monopivot cardiopulmonary bypass pump was manufactured using 3D printing. The 3D-printed impeller was integrated into the pump casing of the commercially available pump to form a 3D-printed pump model. The surface roughness of the impeller, the hydraulic performance, the axial displacement of the rotating impeller, and the hemolytic properties of the 3D-printed model were measured and compared with those of the commercially available model. Although the surface roughness of the 3D-printed model was significantly larger than that of the commercially available model, the hydraulic performance of the two models almost coincided. The hemolysis level of the 3D-printed model roughly coincided with that of the commercially available model under low-pressure head conditions, but increased greatly under high-pressure head conditions, as a result of the narrow gap between the rotating impeller and the pump casing. The gap became narrow under high-pressure head conditions, because the axial thrust applied to the impeller increased with increasing impeller rotational speed. Moreover, the axial displacement of the rotating impeller was twice that of the commercially available model, confirming that the elastic deformation of the 3D-printed impeller was larger than that of the commercially available impeller. These results suggest that trial models manufactured by 3D printing can reproduce the hydraulic performance of the commercial product. However, both the surface roughness and the deformation of the trial models must be considered to precisely evaluate the hemolytic properties of the model.
authors.affiliation: Artificial Organ Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology, 1-2-1 Namiki, Tsukuba, Ibaraki, 305-8564, Japan. masahiro.nishida@aist.go.jp.
authors.forename: Masahiro
authors.identifier: http://orcid.org/0000-0001-8075-2269
authors.initials: M
authors.lastname: Nishida
authors.affiliation: Graduate School of Engineering, Yokohama National University, 79-1 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.
authors.forename: Takumi
authors.initials: T
authors.lastname: Negishi
authors.affiliation: Artificial Organ Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology, 1-2-1 Namiki, Tsukuba, Ibaraki, 305-8564, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Sakota
authors.affiliation: Artificial Organ Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology, 1-2-1 Namiki, Tsukuba, Ibaraki, 305-8564, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Kosaka
authors.affiliation: Artificial Organ Research Group, Health Research Institute, National Institute of Advanced Industrial Science and Technology, 1-2-1 Namiki, Tsukuba, Ibaraki, 305-8564, Japan.
authors.forename: Osamu
authors.initials: O
authors.lastname: Maruyama
authors.affiliation: Graduate School of Engineering, Yokohama National University, 79-1 Tokiwadai, Hodogaya-ku, Yokohama, Kanagawa, 240-8501, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Hyakutake
authors.affiliation: Senko Medical Instrument Manufacturing, Co., Ltd., 2-11-1 Hamakawado, Kasukabe, Saitama, 344-0054, Japan.
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Kuwana
authors.affiliation: Graduate School of Engineering, Kobe University, 1-1 Rokkodai, Nada-ku, Kobe, Hyogo, 657-8501, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Yamane
mesh_terms: D002315:Cardiopulmonary Bypass; D004867:Equipment Design; D006353:Heart-Assist Devices; D006461:Hemolysis; D018056:Hemorheology; D006801:Humans; D011312:Pressure; D066330:Printing, Three-Dimensional
keywords: 3D printing; Hemolysis; Pump performance; Rotary blood pump; Surface roughness