title: High-Frequency Color Doppler Sonography of Bullous Pemphigoid: Correlation With Histologic Findings.
abstract: Bullous pemphigoid is the most frequent autoimmune-mediated blistering skin disease, belonging to the group of subepidermal bullae. We performed high-frequency color Doppler sonography in 3 cases of bullous pemphigoid, in bullous and adjacent non-bullous skin, which showed homogeneous sonographic findings. Subepidermal cystic structures with dermal hypoechogenicity were observed in bullous skin. In nonbullous skin, the dermis showed hypoechogenicity compared to normal skin. Color Doppler signals were increased in both areas. These findings correlate histologically with subepidermal bullae and dermal inflammatory infiltrates.
authors.affiliation: Department of Dermatology, University Hospital San Cecilio, Granada, Spain mporrinobustamante@gmail.com.
authors.forename: María Librada
authors.initials: ML
authors.lastname: Porriño-Bustamante
authors.affiliation: Department of Dermatology, Ultrasound Learning Center Madrid, University Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
authors.forename: Fernando
authors.initials: F
authors.lastname: Alfageme
authors.affiliation: Department of Pathology, University Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
authors.forename: Lola
authors.initials: L
authors.lastname: Suárez
authors.affiliation: Department of Dermatology, Ultrasound Learning Center Madrid, University Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
authors.forename: María Antonia González
authors.initials: MA
authors.lastname: de Domingo
authors.affiliation: Department of Dermatology, Ultrasound Learning Center Madrid, University Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
authors.forename: Mercedes
authors.initials: M
authors.lastname: Hospital
authors.affiliation: Department of Dermatology, Ultrasound Learning Center Madrid, University Hospital Puerta de Hierro, Majadahonda, Madrid, Spain.
authors.forename: Gastón
authors.initials: G
authors.lastname: Roustán
mesh_terms: D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D005260:Female; D006652:Histological Techniques / Q000379:methods; D006801:Humans; D008297:Male; D010391:Pemphigoid, Bullous / Q000000981:diagnostic imaging* / Q000473:pathology; D012867:Skin / Q000000981:diagnostic imaging / Q000473:pathology; D018615:Ultrasonography, Doppler, Color / Q000379:methods*
keywords: bullous dermatoses; bullous pemphigoid; color Doppler sonography; dermatologic sonography; sonography; superficial structures