title: Minimal EEG montage with high yield for the detection of status epilepticus in the setting of postanoxic brain damage.
abstract: For the diagnosis of electrographic seizures or status epilepticus, we reduced the number of EEG-electrodes to make urgent EEG monitoring more feasible. Unlike the current existing research, with mixed results, we studied a specific population with postanoxic brain damage, expecting a higher yield of detection of ictal EEG patterns. In a population treated with therapeutic hypothermia post-cardiac arrest, the initial EEGs were reformatted in a longitudinal, a hairline and an 8-lead montage, and independently reviewed by two investigators. The EEGs were categorized into three categories: one without ictal EEG activity, one with interictal activity and one with probable electrographic seizure(s). Generalized ictal EEG activity was the most frequently observed EEG pattern. The average sensitivity for the detection of probable electrographic seizure(s) was 100 % for the 8-lead montage and 92 % in the hairline montage. In comparison to the routine longitudinal montage, the 8-lead montage proved to be reliable for the detection of electrographic seizure activity in a postanoxic population even with limited training in EEG interpretation. The hairline montage did not suffice with regard to the differential diagnosis of triphasic waves associated with metabolic encephalopathy and generalized nonconvulsive status epilepticus, but nonetheless detected the vast majority of probable electrographic seizure(s). Our results support the use of EEG monitoring with fewer electrodes for the detection of ictal EEG activity in the postanoxic population.
authors.affiliation: Department of Neurology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.
authors.forename: Pieternel
authors.identifier: http://orcid.org/0000-0002-7454-7960
authors.initials: P
authors.lastname: Vanherpe
authors.affiliation: Department of Neurology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium. maarten.schrooten@uzleuven.be.
authors.forename: Maarten
authors.initials: M
authors.lastname: Schrooten
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D004569:Electroencephalography / Q000379:methods*; D005260:Female; D006801:Humans; D020925:Hypoxia-Ischemia, Brain / Q000150:complications*; D008297:Male; D008875:Middle Aged; D013226:Status Epilepticus / Q000175:diagnosis* / Q000209:etiology
keywords: Cardiac arrest; Electrographic seizures; Hairline EEG; Ictal EEG patterns; Postanoxic brain damage