title: Serological evidence of hantavirus infection in an urban area in Mato Grosso State, Brazil.
abstract: BACKGROUND
  In Brazil, Mato Grosso (MT) has the highest number of hantavirus cardiopulmonary syndrome cases. Our study aimed to identify anti-hantavirus antibodies in the sera of patients from Sinop, MT, presenting with acute febrile illness.
  
  
  METHODS
  A retrospective analysis of data for 198 sera samples assessed using enzyme-linked immunosorbent assay (ELISA) was conducted.
  
  
  RESULTS
  Immunoglobulins G (IgGs) against the hantavirus nucleoprotein were found in 13.6% of the tested sera. No sample had immunoglobulin M (IgM) antibodies to hantavirus. Seropositivity occurred mainly in female residents in urban areas who worked around the household.
  
  
  CONCLUSIONS
  Our findings suggest circulation of hantavirus in Sinop.
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Mato Grosso, Sinop, Mato Grosso, Brasil.
authors.forename: Carla Julia da Silva Pessoa
authors.initials: CJ
authors.lastname: Vieira
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Mato Grosso, Sinop, Mato Grosso, Brasil.
authors.forename: David José Ferreira da
authors.initials: DJ
authors.lastname: Silva
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Mato Grosso, Sinop, Mato Grosso, Brasil.
authors.forename: Eriana Serpa
authors.initials: ES
authors.lastname: Barreto
authors.affiliation: Laboratório Municipal de Análises Clínicas, Secretaria Municipal de Saúde de Sinop, Sinop, Mato Grosso, Brasil.
authors.forename: Carlos Eduardo Hassegawa
authors.initials: CE
authors.lastname: Siqueira
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Goiás, Jataí, Goiás, Brasil.
authors.forename: Vivaldo Gomes da
authors.initials: VG
authors.lastname: Costa
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Mato Grosso, Sinop, Mato Grosso, Brasil.
authors.forename: Fábio José
authors.initials: FJ
authors.lastname: Lourenço
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Goiás, Jataí, Goiás, Brasil.
authors.forename: Marcos Lázaro
authors.initials: ML
authors.lastname: Moreli
authors.affiliation: Instituto de Ciências da Saúde, Universidade Federal de Mato Grosso, Sinop, Mato Grosso, Brasil.
authors.forename: Roberta Vieira de Morais
authors.initials: RV
authors.lastname: Bronzoni
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000914:Antibodies, Viral / Q000097:blood*; D001938:Brazil / Q000453:epidemiology; D002648:Child; D002675:Child, Preschool; D004797:Enzyme-Linked Immunosorbent Assay; D005260:Female; D006476:Orthohantavirus / Q000276:immunology*; D018778:Hantavirus Infections / Q000175:diagnosis* / Q000453:epidemiology; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D007075:Immunoglobulin M / Q000097:blood*; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D012424:Rural Population; D016036:Seroepidemiologic Studies; D014505:Urban Population; D055815:Young Adult
chemical_list: D000914:Antibodies, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M