title: Biofunctionalizing nanofibers with carbohydrate blood group antigens.
abstract: A rapid and simple method of biofunctionalising nylon, cellulose acetate, and polyvinyl butyral electrospun nanofibers with blood group glycans was achieved by preparing function-spacer-lipid constructs and simply contacting them to fibers with a piezo inkjet printer. A series of water dispersible amphipathic glycan-spacer constructs were synthesized representing a range ABO and related blood group antigens. After immediate contact of the amphipathic glycan-spacer constructs with nanofiber surfaces they self-assembled and were detectable by enzyme immunoassays with high sensitivity and specificity.
authors.affiliation: Centre for Kode Technology Innovation, School of Engineering Faculty of Design and Creative Technologies, Auckland University of Technology, Auckland, New Zealand.
authors.forename: Katie
authors.initials: K
authors.lastname: Barr
authors.affiliation: Revolution Fibres Limited, Auckland, New Zealand.
authors.forename: Bhuvaneswari
authors.initials: B
authors.lastname: Kannan
authors.affiliation: Shemyakin Institute of Bioorganic Chemistry, Moscow, Russian Federation.
authors.forename: Elena
authors.initials: E
authors.lastname: Korchagina
authors.affiliation: Shemyakin Institute of Bioorganic Chemistry, Moscow, Russian Federation.
authors.forename: Inna
authors.initials: I
authors.lastname: Popova
authors.affiliation: Shemyakin Institute of Bioorganic Chemistry, Moscow, Russian Federation.
authors.forename: Ivan
authors.initials: I
authors.lastname: Ryzhov
authors.affiliation: Centre for Kode Technology Innovation, School of Engineering Faculty of Design and Creative Technologies, Auckland University of Technology, Auckland, New Zealand.
authors.forename: Stephen
authors.initials: S
authors.lastname: Henry
authors.affiliation: Centre for Kode Technology Innovation, School of Engineering Faculty of Design and Creative Technologies, Auckland University of Technology, Auckland, New Zealand.|Shemyakin Institute of Bioorganic Chemistry, Moscow, Russian Federation.
authors.forename: Nicolai
authors.initials: N
authors.lastname: Bovin
mesh_terms: D000017:ABO Blood-Group System / Q000737:chemistry*; D002241:Carbohydrates / Q000737:chemistry*; D006801:Humans; D057139:Nanofibers / Q000737:chemistry*
chemical_list: D000017:ABO Blood-Group System; D002241:Carbohydrates
keywords: Forssman; blood group antigens: ABO; function-spacer-lipid; glyco-surface; glycolipids; nanofibers