title: Chlorhexidine: Patient Bathing and Infection Prevention.
abstract: Healthcare-associated infections (HAIs) are an important cause of morbidity and mortality in the USA. They are associated with a substantial increase in health care costs each year. Fortunately, many HAIs are preventable, and their eradication is a national priority. Chlorhexidine (CHG) bathing has been used as an infection prevention measure, either alone or bundled with other interventions, with mostly beneficial results. The recent surge in its use as an agent of choice for skin antisepsis has lead to concerns over emerging resistance among microorganisms. Moreover, compliance with CHG-bathing protocols is not routinely monitored. Policies developed to determine the best infection prevention practice must consider that a "one-size-fits-all" strategy may lead to the selection of CHG-tolerant microorganisms, thereby emphasizing the need for more robust guidelines and additional studies on the role of chlorhexidine bathing for the prevention of HAIs.
authors.affiliation: Division of Infectious Diseases, Virginia Commonwealth University, VMI Building, Suite 205, P.O Box 980049, Richmond, VA, 23298, USA. Salma.MuhammadAbbas@vcuhealth.org.
authors.forename: Salma
authors.initials: S
authors.lastname: Abbas
authors.affiliation: Division of Infectious Diseases, Virginia Commonwealth University, VMI Building, Suite 205, P.O Box 980049, Richmond, VA, 23298, USA.
authors.forename: Sangeeta
authors.initials: S
authors.lastname: Sastry
keywords: Chlorhexidine bathing; Chlorhexidine resistance; Healthcare-associated infections; Prevention