title: Online Obsessive-Compulsive Disorder Treatment: Preliminary Results of the "OCD? Not Me!" Self-Guided Internet-Based Cognitive Behavioral Therapy Program for Young People.
abstract: BACKGROUND
  The development and evaluation of Internet-delivered cognitive behavioral therapy (iCBT) interventions provides a potential solution for current limitations in the acceptability, availability, and accessibility of mental health care for young people with obsessive-compulsive disorder (OCD). Preliminary results support the effectiveness of therapist-assisted iCBT for young people with OCD; however, no previous studies have examined the effectiveness of completely self-guided iCBT for OCD in young people.
  
  
  OBJECTIVE
  We aimed to conduct a preliminary evaluation of the effectiveness of the OCD? Not Me! program for reducing OCD-related psychopathology in young people (12-18 years). This program is an eight-stage, completely self-guided iCBT treatment for OCD, which is based on exposure and response prevention.
  
  
  METHODS
  These data were early and preliminary results of a longer study in which an open trial design is being used to evaluate the effectiveness of the OCD? Not Me!
  
  
  METHODS
  Participants were required to have at least subclinical levels of OCD to be offered the online program. Participants with moderate-high suicide/self-harm risk or symptoms of eating disorder or psychosis were not offered the program. OCD symptoms and severity were measured at pre- and posttest, and at the beginning of each stage of the program. Data was analyzed using generalized linear mixed models.
  
  
  RESULTS
  A total of 334 people were screened for inclusion in the study, with 132 participants aged 12 to 18 years providing data for the final analysis. Participants showed significant reductions in OCD symptoms (P<.001) and severity (P<.001) between pre- and posttest.
  
  
  CONCLUSIONS
  These preliminary results suggest that fully automated iCBT holds promise as a way of increasing access to treatment for young people with OCD; however, further research needs to be conducted to replicate the results and to determine the feasibility of the program.
  
  
  BACKGROUND
  Australian New Zealand Clinical Trials Registry (ANZCTR): ACTRN12613000152729; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=363654 (Archived by WebCite at http://www.webcitation.org/ 6iD7EDFqH).
authors.affiliation: School of Psychology and Speech Pathology, Faculty of Health Sciences, Curtin University, Perth, Australia. c.rees@curtin.edu.au.
authors.forename: Clare Samantha
authors.identifier: http://orcid.org/0000-0002-4218-5053
authors.initials: CS
authors.lastname: Rees
authors.forename: Rebecca Anne
authors.identifier: http://orcid.org/0000-0001-8925-7002
authors.initials: RA
authors.lastname: Anderson
authors.forename: Robert Thomas
authors.identifier: http://orcid.org/0000-0003-4964-4109
authors.initials: RT
authors.lastname: Kane
authors.forename: Amy Louise
authors.identifier: http://orcid.org/0000-0002-1336-4001
authors.initials: AL
authors.lastname: Finlay-Jones
keywords: Australia; Internet; adolescent; adolescents; anxiety disorders/therapy; computer-assisted/statistics and numerical data; iCBT; obsessive-compulsive disorder; self-care; therapy; treatment outcome; young adult