title: Uncommon clinical presentation of Kimuras disease as bilateral retroauricular masses in a young Malian male: successful surgical approach.
abstract: We present a case of a 27 year-old Malian male referred to our hospital for two large, painless retroauricolar masses that had appeared two years earlier. Bilateral cervical painless lymphadenopathy was present at physical examination, without any other systemic symptoms. His history was relevant for bilateral Kimuras disease lesions resected 5 years earlier in the same locations. Lymphocytosis and a mild hypereosinophilia were found in routine blood tests, together with increased total IgE levels. After surgery, histology showed lymphoid infiltrates with reactive prominent germinal centres containing eosinophils, suggesting relapse of Kimuras disease, in the context of nonencapsulated fibrous proliferation with discontinuous collagen fibers, consistent with keloid. Three months after removal of retroauricular masses, abnormal laboratory findings reverted to normal. To the best our knowledge, this is the first case in literature of bilateral keloid lesions developed after surgery for Kimura Disease and harbouring its histopathologic features. Clinicians should be aware of these unusual reactive phenomena and their possible simulators.
authors.affiliation: Department of Human Pathology, University Hospital of Messina, Messina, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Fama
authors.affiliation: Department of Biomedical and Dental Sciences and of Morphological and Functional Images, University Hospital of Messina, Messina, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Sindoni
authors.affiliation: Medical Institute of Ministry of Interior (MVR-Sofia), Department of Dermatology, Venereology and Dermatologic Surgery, Sofia, Bulgaria.
authors.forename: G
authors.initials: G
authors.lastname: Tchernev
authors.affiliation: Onkoderma- Policlinic for Dermatology and Dermatologic Surgery, Sofia, Bulgaria; Department of Dermatology and Venereology, Medical University of Plovdiv, Medical Faculty, Plovdiv, Bulgaria.
authors.forename: A A
authors.initials: AA
authors.lastname: Chokoeva
authors.affiliation: Department of Dermatology and Allergology, Academic Teaching Hospital Dresden-Friedrichstadt, Dresden, Germany.
authors.forename: U
authors.initials: U
authors.lastname: Wollina
authors.affiliation: Department of Dermatology, University of Rome G. Marconi Rome, Italy.
authors.forename: T
authors.initials: T
authors.lastname: Lotti
authors.affiliation: Department Medicinal Information and Non-Interventional Studies, Bulgarian Drug Agency, Sofia, Bulgaria.
authors.forename: G K
authors.initials: GK
authors.lastname: Maximov
authors.affiliation: University of Virginia Health System, Department of Pathology, Charlottesville, VA USA.
authors.forename: J W
authors.initials: JW
authors.lastname: Patterson
authors.affiliation: History Department, G.Marconi University, Rome, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Fioranelli
authors.affiliation: University B.I.S. Group of Institutions, Punjab Technical University, Punjab, India.
authors.forename: M G
authors.initials: MG
authors.lastname: Roccia
authors.affiliation: Department of Human Pathology, University Hospital of Messina, Messina, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Ieni
authors.affiliation: Department of Human Pathology, University Hospital of Messina, Messina, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cascio
authors.affiliation: Department of Human Pathology, University Hospital of Messina, Messina, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Gioffre-Florio
authors.affiliation: Department of Clinical and Experimental Medicine - Section of Dermatology, University Hospital of Messina, Messina, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Guarneri
mesh_terms: D000328:Adult; D000796:Angiolymphoid Hyperplasia with Eosinophilia / Q000473:pathology* / Q000601:surgery*; D005355:Fibrosis; D006801:Humans; D008297:Male; D012008:Recurrence; D016896:Treatment Outcome