title: A Systematic Review of Ileal Conduit and Neobladder Outcomes in Primary Bladder Cancer.
abstract: Treatment for muscle invasive bladder cancer with curative intent includes radical cystectomy and urinary diversion. Using PRISMA guidelines, we conducted a systematic review assessing differences in patient selection, operative parameters, complications, and quality of life between ileal conduit and neobladder cohorts. Ileal conduit cohorts have more advanced age and disease, more comorbidities and complications, and poorer quality of life. Ileal conduit surgery is associated with adverse patient selection that inhibits reasonable comparison of outcomes with neobladder cohorts. Despite this, we observe longer operative times and hospital stays in neobladder cohorts, perhaps reflecting greater technical difficulty and the need for postoperative bladder training.
authors.affiliation: Department of Surgery, Austin Hospital, University of Melbourne, Melbourne, Victoria, Australia; Austin Hospital, Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia. Electronic address: jackacrozier@gmail.com.
authors.forename: Jack
authors.initials: J
authors.lastname: Crozier
authors.affiliation: Austin Hospital, Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia.
authors.forename: Derek
authors.initials: D
authors.lastname: Hennessey
authors.affiliation: Department of Surgery, Austin Hospital, University of Melbourne, Melbourne, Victoria, Australia; Austin Hospital, Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia.
authors.forename: Shomik
authors.initials: S
authors.lastname: Sengupta
authors.affiliation: Department of Surgery, Austin Hospital, University of Melbourne, Melbourne, Victoria, Australia; Austin Hospital, Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia.
authors.forename: Damien
authors.initials: D
authors.lastname: Bolton
authors.affiliation: Department of Surgery, Austin Hospital, University of Melbourne, Melbourne, Victoria, Australia; Austin Hospital, Olivia Newton-John Cancer Research Institute, Melbourne, Victoria, Australia; Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
authors.forename: Nathan
authors.initials: N
authors.lastname: Lawrentschuk
mesh_terms: D006801:Humans; D016896:Treatment Outcome; D001749:Urinary Bladder Neoplasms / Q000601:surgery*; D014547:Urinary Diversion; D016476:Urinary Reservoirs, Continent