title: Adsorption of Amino Acids and Peptides on Metal and Oxide Surfaces in Water Environment: A Synthetic and Prospective Review.
abstract: Amino acids and peptides are often used as "model" segments of proteins for studying their behavior in various types of environments, and/or elaborating functional surfaces. Indeed, though the protein behavior is much more complex than that of their isolated segments, knowledge of the binding mode as well as of the chemical structure of peptides on metal or oxide surfaces is a significant step toward the control of materials in a biological environment. Such knowledge has considerably increased in the past few years, thanks to the combination of advanced characterization techniques and of modeling methods. Investigations of biomolecule-surface interactions in water/solvent environments are quite numerous, but only in a few cases is it possible to reach an understanding of the molecule-(water)-surface interaction with a level of detail comparable to that of the UHV studies. This contribution aims at reviewing the recent data describing the amino acid and peptide interaction with metal or oxide surfaces in the presence of water.
authors.affiliation: Institut de Recherches de Chimie de Paris UMR 8247 ENSCP Chimie Paristech , 11 Rue P. Et M. Curie, 75005 Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Costa
authors.affiliation: Istituto dei Materiali per l'Elettronica e il Magnetismo, Consiglio Nazionale delle Ricerche, U.O.S. Genova , Via Dodecaneso 33, 16146 Genova, Italy.
authors.forename: L
authors.initials: L
authors.lastname: Savio
authors.affiliation: Laboratoire de Réactivité de Surface, Sorbonne Université, UPMC Univ Paris 06, UMR CNRS 7197 , 4 Place Jussieu, 75231 Paris Cedex 05, France.
authors.forename: C-M
authors.initials: CM
authors.lastname: Pradier
mesh_terms: D000327:Adsorption; D000596:Amino Acids / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D008670:Metals / Q000737:chemistry*; D010087:Oxides / Q000737:chemistry; D010455:Peptides / Q000737:chemistry*; D056951:Photoelectron Spectroscopy; D011446:Prospective Studies; D012997:Solvents / Q000737:chemistry; D013499:Surface Properties; D013816:Thermodynamics
chemical_list: D000596:Amino Acids; D008670:Metals; D010087:Oxides; D010455:Peptides; D012997:Solvents