title: Lesch-Nyhan Syndrome: Disorder of Self-mutilating Behavior.
abstract: Lesch-Nyhan syndrome (LNS), a rare inborn error of metabolism, is characterized by self-injurious behavior, which results in partial or total destruction of oral and perioral tissues and/ or fingers. Persistent self-injurious behavior (biting the fingers, hands, lips, and cheeks; banging the head or limbs) is a hallmark of the disease. Prevention of self-mutilation raises significant difficulties. A case of a 10-month-old boy with aggressive behavior and severe lower lip injuries is presented. How to cite this article: Jathar P, Panse AM, Jathar M, Gawali PN. Lesch-Nyhan Syndrome: Disorder of Self-mutilating Behavior. Int J Clin Pediatr Dent 2016;9(2):139-142.
authors.affiliation: Reader, Department of Pedodontics and Preventive Dentistry, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
authors.forename: Prasad
authors.initials: P
authors.lastname: Jathar
authors.affiliation: Senior Lecturer, Department of Pedodontics and Preventive Dentistry, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
authors.forename: Amey M
authors.initials: AM
authors.lastname: Panse
authors.affiliation: Senior Lecturer, Department of Oral Medicine and Radiology, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
authors.forename: Madhura
authors.initials: M
authors.lastname: Jathar
authors.affiliation: Postgraduate Student, Department of Pedodontics and Preventive Dentistry, Sinhgad Dental College and Hospital, Pune, Maharashtra, India.
authors.forename: Pritesh N
authors.initials: PN
authors.lastname: Gawali
keywords: HPRT enzyme; Lesch-Nyhan syndrome; Self-mutilating behavior.