title: Optically controlled release of DNA based on nonradiative relaxation process of quenchers.
abstract: Optically controlled release of a DNA strand based on a nonradiative relaxation process of black hole quenchers (BHQs), which are a sort of dark quenchers, is presented. BHQs act as efficient energy sources because they relax completely via a nonradiative process, i.e., without fluorescent emission-based energy losses. A DNA strand is modified with BHQs and the release of its complementary strand is controlled by excitation of the BHQs. Experimental results showed that up to 50% of the target strands were released, and these strands were capable of inducing subsequent reactions. The controlled release was localized on a substrate within an area of no more than 5 micrometers in diameter.
authors.affiliation: Graduate School of Information Science and Technology, Osaka University, Suita, Osaka, 5650871, Japan.
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Ogura
authors.affiliation: Graduate School of Information Science and Technology, Osaka University, Suita, Osaka, 5650871, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Onishi
authors.affiliation: Graduate School of Information Science and Technology, Osaka University, Suita, Osaka, 5650871, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nishimura
authors.affiliation: Graduate School of Information Science and Technology, Osaka University, Suita, Osaka, 5650871, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Tanida
keywords: (350.4600) Optical engineering; (350.5340) Photothermal effects