title: Prevalence of Spina Bifida Occulta and Its Relationship With Overactive Bladder in Middle-Aged and Elderly Chinese People.
abstract: OBJECTIVE
  To investigate the prevalence of spina bifida occulta (SBO) and its relationship with the presence of overactive bladder (OAB) in middle-aged and elderly people in China.
  
  
  METHODS
  A cross-sectional community-based survey was carried out at 7 communities in Zhengzhou City, China from December 15, 2013 to June 10, 2014, where residents aged over 40 years were randomly selected to participate. All of the participants underwent lumbosacral radiographic analysis and relevant laboratory tests. A questionnaire including basic information, past medical history and present illness, and the OAB symptom score was filled out by all participants. Chi-square tests and logistic regression were used for data analysis with a P-value of <0.05 denoting statistical significance.
  
  
  RESULTS
  A total of 1,061 subjects were qualified for the final statistical analysis (58.8±11.7 years; male, 471 [44.4%]; female, 590 [55.6%]). The overall prevalence of SBO was 15.1% (160 of 1,061): 18.3% (86 of 471) in men and 12.5% (74 of 590) in women. Among these subjects, 13.7% (145 of 1,061) had OAB: 13.2% (62 of 471) in men and 14.1% (83 of 590) in women. The results of logistic regression showed that age, SBO, history of cerebral infarction (HCI), and constipation were risk factors for OAB (P<0.05), while sex, history of childhood enuresis (HCE), body mass index (BMI), and diabetes mellitus (DM) were not (P>0.05). In men, age, SBO, and constipation were risk factors for OAB (P<0.05), while HCE, BMI, DM, HCI, and benign prostate hyperplasia were not (P>0.05). In women, age, SBO, and HCI were risk factors for OAB (P<0.05), while HCE, BMI, DM, vaginal delivery, and constipation were not (P>0.05).
  
  
  CONCLUSIONS
  The prevalence of SBO is high and it is related to OAB in middle-aged and elderly people in China.
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Jun Wei
authors.identifier: 0000-0002-6876-4934
authors.initials: JW
authors.lastname: Wu
authors.affiliation: Center of Health Examination, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Yu Rong
authors.identifier: 0000-0002-3009-5456
authors.initials: YR
authors.lastname: Xing
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Yi Bo
authors.identifier: 0000-0001-7835-7083
authors.initials: YB
authors.lastname: Wen
authors.affiliation: Department of Rheumatology & Immunology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Tian Fang
authors.identifier: 0000-0003-2298-6184
authors.initials: TF
authors.lastname: Li
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Jia Feng
authors.identifier: 0000-0003-4467-6179
authors.initials: JF
authors.lastname: Xie
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Quan De
authors.identifier: 0000-0002-3512-3006
authors.initials: QD
authors.lastname: Feng
authors.affiliation: Medical Record Department, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Xiao Ping
authors.identifier: 0000-0002-7886-4656
authors.initials: XP
authors.lastname: Shang
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Yun Long
authors.identifier: 0000-0001-5527-2116
authors.initials: YL
authors.lastname: Li
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Jin Jin
authors.identifier: 0000-0001-9269-9557
authors.initials: JJ
authors.lastname: Feng
authors.affiliation: Reproductive Medical Centre, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
authors.forename: Xin Xin
authors.identifier: 0000-0003-1407-5364
authors.initials: XX
authors.lastname: Wang
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Rong Qun
authors.identifier: 0000-0002-3173-3480
authors.initials: RQ
authors.lastname: Zhai
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Xiang Fei
authors.identifier: 0000-0001-7017-9331
authors.initials: XF
authors.lastname: He
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Tao
authors.identifier: 0000-0003-3139-1158
authors.initials: T
authors.lastname: Chen
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Xin Jian
authors.identifier: 0000-0001-5113-762X
authors.initials: XJ
authors.lastname: Liu
authors.affiliation: Urodynamic Centre, Department of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.|Key-Disciplines Laboratory Clinical-Medicine Henan, Zhengzhou, China.
authors.forename: Jian Guo
authors.identifier: 0000-0003-0952-118X
authors.initials: JG
authors.lastname: Wen
keywords: Aged; Prevalence; Spina Bifida Occulta; Urinary Bladder, Overactive