title: Imprinting defects in osteosarcoma: DNA- and chromatin-modifying drugs hold promise for osteosarcoma therapy.
authors.affiliation: Department of Surgery, University of Minnesota, 11-212 Moos Tower (Mail code: MMC 195) 420 Delaware St, S.E Minneapolis, MN 55455, USA.
authors.forename: Anne E
authors.initials: AE
authors.lastname: Sarver
authors.affiliation: Department of Surgery, University of Minnesota, 11-212 Moos Tower (Mail code: MMC 195) 420 Delaware St, S.E Minneapolis, MN 55455, USA.|Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA.
authors.forename: Subbaya
authors.initials: S
authors.lastname: Subramanian
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D001859:Bone Neoplasms / Q000188:drug therapy / Q000235:genetics / Q000473:pathology; D042002:Chromatin Assembly and Disassembly / Q000187:drug effects*; D004247:DNA / Q000737:chemistry / Q000187:drug effects*; D019175:DNA Methylation / Q000187:drug effects; D015254:DNA Modification Methylases / Q000037:antagonists & inhibitors / Q000378:metabolism; D018392:Genomic Imprinting; D006801:Humans; D009154:Mutation; D012516:Osteosarcoma / Q000188:drug therapy / Q000235:genetics / Q000473:pathology
chemical_list: D000970:Antineoplastic Agents; D004247:DNA; D015254:DNA Modification Methylases
keywords: 14q32-locus; DNA methylation; chromatin modifying drugs; epigenomics; imprinting; miRNA; osteosarcoma