title: Combined monitoring of intracranial pressure and bispectral index in patients with severe craniocerebral trauma post-operatively.
abstract: OBJECTIVE
  To investigate the value of simultaneous bispectral index (BIS) and intracranial pressure (ICP) monitoring to evaluate postoperative consciousness and short-term prognosis in patients with severe traumatic brain injury.
  
  
  METHODS
  We evaluated 30 brain trauma coma patients in the People's Hospital of Northern Jiangsu Province from January 2014 to December 2014 and evaluated Glasgow Coma Scale (GCS) scores at 8-h intervals for 3days after surgery. BIS and ICP values were recorded at the same time. Based on the GCS score, patients were divided into two groups: group A (GCS score 3-≤5) and group B (>5-≤8). Natural survival rates were analyzed statistically and compared between groups.
  
  
  RESULTS
  Chi-square testing revealed a significant difference in survival rates between the groups (P<0.05). Spearman's rank correlation analysis revealed that BIS value was positively correlated with coma degree post-operatively in patients with severe traumatic brain injury, and negatively correlated with ICP values (r=0.532, P<0.05; r=0.521, P<0.05, respectively).
  
  
  CONCLUSIONS
  In patients with severe craniocerebral injury, higher severity, higher ICP, and lower BIS were associated with a worse prognosis. Combined monitoring of BIS and ICP is very useful when evaluating the coma degree and prognosis of patients with severe craniocerebral injury post-operatively.
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China. Electronic address: dongluen@163.com.
authors.forename: L
authors.initials: L
authors.lastname: Dong
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China. Electronic address: chenlangdoctor@hotmail.com.
authors.forename: L
authors.initials: L
authors.lastname: Chen
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China.
authors.forename: T
authors.initials: T
authors.lastname: Shi
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China.
authors.forename: M
authors.initials: M
authors.lastname: Wei
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China. Electronic address: zhanghengzhu@sina.com.
authors.forename: H Z
authors.initials: HZ
authors.lastname: Zhang
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China.
authors.forename: Y P
authors.initials: YP
authors.lastname: Li
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China.
authors.forename: L
authors.initials: L
authors.lastname: She
authors.affiliation: Department of Neurosurgery, Clinical Medical College of Yangzhou University, Yangzhou, Jiangsu 225001, PR China.
authors.forename: Z C
authors.initials: ZC
authors.lastname: Yan
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia; D000070642:Brain Injuries, Traumatic / Q000601:surgery*; D005260:Female; D015600:Glasgow Coma Scale; D006801:Humans; D007427:Intracranial Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D064926:Neurophysiological Monitoring / Q000379:methods*; D017063:Outcome Assessment, Health Care; D011184:Postoperative Period; D055815:Young Adult
keywords: Bispectral index (BIS); Brain injury; Craniocerebral injury; Intracranial pressure (ICP); Monitoring; Prognosis