title: Ionic liquid coated copper wires and tubes for fiber-in-tube solid-phase microextraction.
abstract: A fiber-in-tube solid-phase microextraction (SPME) device was developed by filling eleven copper wires into a copper tube, and all of those were functionalized with ionic liquids. Its morphology and surface properties were characterized by scanning electron microscopy. It was connected into high performance liquid chromatography (HPLC) equipment by replacing the sample loop of six-port injection valve, building the online SPME-HPLC system. In the optimization of extraction conditions, sampling rate, sample volume, pH of sample and desorption time were investigated with five estrogens as model analytes. Under the optimum conditions, an online SPME-HPLC analysis method was achieved, showing enrichment efficiency from 611 to 1661 and a good linearity of 0.06-60μgL(-1) with low detection limits of 0.02-0.05μgL(-1). It was applied to detect estrogens analytes in two water samples, with recoveries in the range of 85-114%. Relative standard deviation (n=3) of extraction repeatability is in the range of 1.9-3.0%. Relative standard deviation of extraction tubes (n=3) is in the range of 12-19%. The extraction mechanism is probably related to hydrophobic, π-π and dipole-dipole interactions between ionic liquids coating and estrogens analytes.
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.
authors.forename: Min
authors.initials: M
authors.lastname: Sun
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China. Electronic address: chm_fengjuanjuan@ujn.edu.cn.
authors.forename: Juanjuan
authors.initials: J
authors.lastname: Feng
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.
authors.forename: Yanan
authors.initials: Y
authors.lastname: Bu
authors.affiliation: Key Laboratory of Chemical Sensing & Analysis in Universities of Shandong (University of Jinan), School of Chemistry and Chemical Engineering, University of Jinan, Jinan 250022, China.
authors.forename: Chuannan
authors.initials: C
authors.lastname: Luo
mesh_terms: D002851:Chromatography, High Pressure Liquid; D003300:Copper / Q000737:chemistry*; D004967:Estrogens / Q000032:analysis* / Q000302:isolation & purification*; D057927:Hydrophobic and Hydrophilic Interactions; D052578:Ionic Liquids / Q000737:chemistry*; D057230:Limit of Detection; D008855:Microscopy, Electron, Scanning; D052617:Solid Phase Microextraction / Q000295:instrumentation*; D014867:Water / Q000737:chemistry
chemical_list: D004967:Estrogens; D052578:Ionic Liquids; D014867:Water; D003300:Copper
keywords: Estrogens; Fiber-in-tube; High performance liquid chromatography; Ionic liquids; Online analysis; Solid-phase microextraction