title: A randomized clinical study for comparative evaluation of Aloe Vera and 0.2% chlorhexidine gluconate mouthwash efficacy on de-novo plaque formation.
abstract: OBJECTIVE
  To comparatively assess the antiplaque efficacy of Aloe vera mouthwash and 0.2% chlorhexidine gluconate mouthwash on de novo plaque formation.
  
  
  METHODS
  This was a randomized, single blind, parallel, controlled clinical study with 90 healthy participants, with mean age of 27.19 ± 12.08 years. After thorough oral prophylaxis, participants were instructed to discontinue mechanical plaque control. Participants were divided randomly into three groups; pure Aloe vera mouthwash was dispensed to the test group; control group received 0.2% chlorhexidine gluconate mouthwash; in Placebo group, flavored distilled water was used as oral rinse twice daily. Effect on 4-day de novo plaque formation was assessed by comparing pre-rinsing Quigley Hein Modified Plaque Scores were analyzed statistically using analysis of variance and Student's t-test.
  
  
  RESULTS
  Post-rinsing control group showed the least plaque score which was comparable to the test group. Both the control group and test group showed significant difference with the placebo group.
  
  
  CONCLUSIONS
  Herbal mouthwash containing Aloe vera mouthwash has comparable antiplaque efficacy as the gold standard 0.2% chlorhexidine gluconate with fewer side effects and can be considered as an alternative.
authors.affiliation: Department of Periodontics, ITS Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India.
authors.forename: Shivjot
authors.initials: S
authors.lastname: Chhina
authors.affiliation: Department of Public Health Dentistry, ITS Dental College, Muradnagar, Ghaziabad, Uttar Pradesh, India.
authors.forename: Avnish
authors.initials: A
authors.lastname: Singh
authors.affiliation: Department of Public Health Dentistry, ITS Dental College, Muradnagar, Ghaziabad, Uttar Pradesh, India.
authors.forename: Ipseeta
authors.initials: I
authors.lastname: Menon
authors.affiliation: Department of Public Health Dentistry, ITS Dental College, Muradnagar, Ghaziabad, Uttar Pradesh, India.
authors.forename: Rickypal
authors.initials: R
authors.lastname: Singh
authors.affiliation: Department of Public Health Dentistry, ITS Dental College, Muradnagar, Ghaziabad, Uttar Pradesh, India.
authors.forename: Anubhav
authors.initials: A
authors.lastname: Sharma
authors.affiliation: Department of Periodontics, ITS Dental College, Hospital and Research Centre, Greater Noida, Uttar Pradesh, India.
authors.forename: Vartika
authors.initials: V
authors.lastname: Aggarwal
keywords: Aloe vera; antiplaque efficacy; chlorhexidine; plaque index