title: First Imported Case of Zika Virus Infection into Korea.
abstract: Since Zika virus has been spreading rapidly in the Americas from 2015, the outbreak of Zika virus infection becomes a global health emergency because it can cause neurological complications and adverse fetal outcome including microcephaly. Here, we report clinical manifestations and virus isolation findings from a case of Zika virus infection imported from Brazil. The patient, 43-year-old Korean man, developed fever, myalgia, eyeball pain, and maculopapular rash, but not neurological manifestations. Zika virus was isolated from his semen, and reverse-transcriptase PCR was positive for the virus in the blood, urine, and saliva on the 7th day of the illness but was negative on the 21st day. He recovered spontaneously without any neurological complications. He is the first case of Zika virus infection in Korea imported from Brazil.
authors.affiliation: Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea .
authors.forename: Hee-Chang
authors.identifier: 0000-0002-3407-8493
authors.initials: HC
authors.lastname: Jang
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: Wan Beom
authors.identifier: 0000-0003-0022-9625
authors.initials: WB
authors.lastname: Park
authors.affiliation: Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea .
authors.forename: Uh Jin
authors.identifier: 0000-0002-8463-6297
authors.initials: UJ
authors.lastname: Kim
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: June Young
authors.identifier: 0000-0001-9345-6645
authors.initials: JY
authors.lastname: Chun
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: Su-Jin
authors.identifier: 0000-0001-8732-3950
authors.initials: SJ
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: Pyoeng Gyun
authors.identifier: 0000-0001-6794-7918
authors.initials: PG
authors.lastname: Choe
authors.affiliation: Department of Infectious Diseases, Chonnam National University Medical School, Gwangju, Korea .
authors.forename: Sook-In
authors.identifier: 0000-0002-1577-678X
authors.initials: SI
authors.lastname: Jung
authors.affiliation: Center for Pathology and Immunology, National Institute of Health, Korea Centers for Disease Control and Prevention, Osong, Korea.
authors.forename: Youngmee
authors.initials: Y
authors.lastname: Jee
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: Nam-Joong
authors.identifier: 0000-0001-6793-9467
authors.initials: NJ
authors.lastname: Kim
authors.affiliation: Department of Pediatrics, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: Eun Hwa
authors.identifier: 0000-0002-5857-0749
authors.initials: EH
authors.lastname: Choi
authors.affiliation: Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea .
authors.forename: Myoung-Don
authors.identifier: 0000-0002-2344-7695
authors.initials: MD
authors.lastname: Oh
mesh_terms: D000328:Adult; D001938:Brazil; D006801:Humans; D008297:Male; D046529:Microscopy, Electron, Transmission; D012367:RNA, Viral / Q000032:analysis / Q000097:blood / Q000652:urine; D056910:Republic of Korea; D020133:Reverse Transcriptase Polymerase Chain Reaction; D012463:Saliva / Q000821:virology; D012661:Semen / Q000821:virology; D014195:Travel; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000175:diagnosis* / Q000821:virology
chemical_list: D012367:RNA, Viral
keywords: Brazil; Korea; Travel; Virus Shedding; Zika Virus