title: Prospective small bowel mucosal assessment immediately after chemoradiotherapy of unresectable locally advanced pancreatic cancer using capsule endoscopy: a case series.
abstract: In this case series, three consecutive patients with unresectable locally advanced pancreatic cancer (ULAPC) underwent capsule endoscopy (CE) before and after chemoradiotherapy (CRT) to evaluate duodenal and jejunal mucosa, and to examine the relationship between CE findings and dose distribution. CE after CRT showed duodenitis and proximal jejunitis in all three patients. The most inflamed region was the third part of the duodenum, and in dose distribution, this was the closest region to the center of irradiation. This case series shows that CE can safely diagnose acute duodenitis and proximal jejunitis caused by CRT for ULAPC, and that dose distribution is possible to predict the degree of duodenal and jejunal mucosal injuries.
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan; Department of Gastroenterology and Hepatology, Osaka Red Cross Hospital (Takeshi Yamashina), Osaka, Japan.
authors.forename: Takeshi
authors.initials: T
authors.lastname: Yamashina
authors.affiliation: Department of Pancreatic Oncology (Ryoji Takeda), Osaka, Japan.
authors.forename: Ryoji
authors.initials: R
authors.lastname: Takada
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Noriya
authors.initials: N
authors.lastname: Uedo
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Tomofumi
authors.initials: T
authors.lastname: Akasaka
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Noboru
authors.initials: N
authors.lastname: Hanaoka
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Yoji
authors.initials: Y
authors.lastname: Takeuchi
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Koji
authors.initials: K
authors.lastname: Higashino
authors.affiliation: Department of Cancer Survey (Tatsuya Ioka), Osaka, Japan.
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Ioka
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Ryu
authors.initials: R
authors.lastname: Ishihara
authors.affiliation: Department of Radiation Oncology (Teruki Teshima, Kinji Nishiyama), Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka, Japan.
authors.forename: Teruki
authors.initials: T
authors.lastname: Teshima
authors.affiliation: Department of Radiation Oncology (Teruki Teshima, Kinji Nishiyama), Osaka Medical Center for Cancer and Cardiovascular Disease, Osaka, Japan.
authors.forename: Kinji
authors.initials: K
authors.lastname: Nishiyama
authors.affiliation: Gastrointestinal Oncology (Takeshi Yamashina, Noriya Uedo, Tomofumi Akasaka, Noboru Hanaoka, Yoji Takeuchi, Koji Higashino, Ruy Ishihara, Hiroyasu Iishi), Osaka, Japan.
authors.forename: Hiroyasu
authors.initials: H
authors.lastname: Iishi
keywords: Radiation enteritis; capsule endoscopy; pancreatic cancer