title: A comprehensive review of bioimpedance spectroscopy as a diagnostic tool for the detection and measurement of breast cancer-related lymphedema.
abstract: As treatment for breast cancer improves and the threat of life-long chronic lymphedema becomes more prevalent, the need for effective screening tools emerges as crucial. This review was conducted using literature beginning in 1992 to analyze primary research testing the accuracy of bioimpedance spectroscopy as a diagnostic and early detection tool for breast cancer-related lymphedema. We concluded bioimpedance is an accurate diagnostic tool for pre-existent lymphedema, however, it has not been validated for early detection. J. Surg. Oncol. 2016;114:537-542. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Department of Radiation Oncology, Lymphedema Studies Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Cara
authors.initials: C
authors.lastname: Seward
authors.affiliation: Department of Radiation Oncology, Lymphedema Studies Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Melissa
authors.initials: M
authors.lastname: Skolny
authors.affiliation: Department of Physical and Occupational Therapy, Massachusetts General Hospital, Boston, Massachusetts.
authors.forename: Cheryl
authors.initials: C
authors.lastname: Brunelle
authors.affiliation: Department of Radiation Oncology, Lymphedema Studies Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Maria
authors.initials: M
authors.lastname: Asdourian
authors.affiliation: Department of Radiation Oncology, Lymphedema Studies Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts.
authors.forename: Laura
authors.initials: L
authors.lastname: Salama
authors.affiliation: Department of Radiation Oncology, Lymphedema Studies Program, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts. ataghian@partners.org.
authors.forename: Alphonse G
authors.initials: AG
authors.lastname: Taghian
mesh_terms: D000072656:Breast Cancer Lymphedema / Q000175:diagnosis*; D058266:Dielectric Spectroscopy; D017097:Electric Impedance; D006801:Humans; D011237:Predictive Value of Tests
keywords: L-Dex; bioimpedance spectroscopy; breast cancer-related lymphedema (BCRL); early detection; multiple frequency bioimpedance analysis (MFBIA); perometry