title: Successful treatment of proximal renal tubular acidosis and Fanconi syndrome with vitamin D replacement.
abstract: Proximal renal tubular acidosis (RTA), also known as Type II RTA, is characterized by a defect in the ability to reabsorb bicarbonate (HCO 3 ) in the proximal tubule. It is usually associated with generalized dysfunction of the proximal tubule as part of Fanconi syndrome. Very few case reports in the literature support Vitamin D deficiency as a cause of proximal RTA. We present a case of a young female who presented with proximal RTA and Fanconi syndrome and excellently responded to Vitamin D replacement. Thus, work-up for the etiology of proximal RTA should include Vitamin D levels since replacement of this vitamin in those who are deficient can lead to cure of such patients.
authors.affiliation: Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Syed Ahsan
authors.initials: SA
authors.lastname: Ali
authors.affiliation: Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Tariq
mesh_terms: D000141:Acidosis, Renal Tubular; D001639:Bicarbonates; D005198:Fanconi Syndrome; D005260:Female; D006801:Humans; D014807:Vitamin D; D014815:Vitamins
chemical_list: D001639:Bicarbonates; D014815:Vitamins; D014807:Vitamin D