title: Clinical, demographic, and radiographic analysis of 82 patients affected by florid osseous dysplasia: an international collaborative study.
abstract: OBJECTIVE
  The aim of this study was to correlate the clinical, demographic, and radiographic aspects of 82 cases of florid osseous dysplasia (FOD) from four countries assessed by five reviewers.
  
  
  METHODS
  Retrospective data of patients diagnosed with FOD were obtained from archives of five institutes and analyzed according to clinical and radiographic criteria.
  
  
  RESULTS
  A total of 82 cases of FOD were included in the study. In the majority (77.5%) of FOD cases, black women were affected. The disease mainly affected the mandible (100%), and the stage of the lesion was directly correlated with the age (P < .05). The rates of convergence showed confluence of assessment in the mandible (posterior), and the highest rate of divergence between the reviewers was in assessing involvement in the maxilla. There were no differences among the characteristics of the lesion provided by the five institutions, except for the variable proportion of black patients affected by the disease.
  
  
  CONCLUSIONS
  FOD mostly affects the mandible of middle-aged black women, and its stage is correlated with patient age. Although panoramic radiography is used for diagnosis, the divergence in assessment of the maxilla might indicate that this method is not the most suitable to evaluate this area.
authors.affiliation: Oral Diagnosis Department, Piracicaba Dental School, University of Campinas - UNICAMP, Piracicaba, Sao Paulo, Brazil.
authors.forename: Débora Lima
authors.initials: DL
authors.lastname: Pereira
authors.affiliation: Oral Pathology, State University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
authors.forename: Fábio Ramôa
authors.initials: FR
authors.lastname: Pires
authors.affiliation: Oral Diagnosis Department, Piracicaba Dental School, University of Campinas - UNICAMP, Piracicaba, Sao Paulo, Brazil.
authors.forename: Márcio Ajudarte
authors.initials: MA
authors.lastname: Lopes
authors.affiliation: Head and Neck Clinical Center, Ciudad de Guatemala, Guatemala.
authors.forename: Román
authors.initials: R
authors.lastname: Carlos
authors.affiliation: Department of Diagnostic Sciences, Texas A&M University Baylor College of Dentistry, Dallas, TX, USA.
authors.forename: John Marshal
authors.initials: JM
authors.lastname: Wright
authors.affiliation: Department of Diagnostic Sciences, Texas A&M University Baylor College of Dentistry, Dallas, TX, USA.
authors.forename: Paras
authors.initials: P
authors.lastname: Patel
authors.affiliation: Department of Oral Pathology and Oral Biology, University of Pretoria, Pretoria, South Africa.
authors.forename: Willie
authors.initials: W
authors.lastname: van Heerden
authors.affiliation: Department of Oral Pathology and Oral Biology, University of Pretoria, Pretoria, South Africa.
authors.forename: Andre
authors.initials: A
authors.lastname: Uys
authors.affiliation: Oral Diagnosis Department, Piracicaba Dental School, University of Campinas - UNICAMP, Piracicaba, Sao Paulo, Brazil. Electronic address: Pavargas@fop.unicamp.br.
authors.forename: Pablo Agustin
authors.initials: PA
authors.lastname: Vargas
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D003937:Diagnosis, Differential; D005260:Female; D005357:Fibrous Dysplasia of Bone / Q000000981:diagnostic imaging* / Q000208:ethnology* / Q000473:pathology*; D006801:Humans; D038622:Internationality; D008297:Male; D008875:Middle Aged; D010019:Osteomyelitis / Q000000981:diagnostic imaging* / Q000208:ethnology* / Q000473:pathology*; D011862:Radiography, Panoramic; D012189:Retrospective Studies