title: Presentation, Management, and Outcome of Thyroglossal Duct Cysts in Adult and Pediatric Populations: A 14-Year Single Center Experience.
abstract: OBJECTIVE
  A thyroglossal duct cyst (TDC) is a frequent congenital midline anomaly of the neck that usually manifests during the first decade of life. We aimed to describe the presentation, management, and outcome of TDC in pediatric and adult cases.
  
  
  METHODS
  A retrospective observational analysis was conducted for all patients diagnosed and treated for TDC between 2000 and 2014 in a single center in Qatar. Data included patients' demographics, presentations, preoperative investigations, anesthesia type, histopathological findings, surgical management, recurrences, and complications.
  
  
  RESULTS
  We identified 102 patients, of which 57% were males. The mean age of patients was 20.2±15.6 years. A bimodal distribution of TDC has been observed, which peaked between the ages of 6-13 years and at ≥19 years. The preoperative evaluation mainly includes ultrasonography (66%), thyroid function test (44%), and fine-needle aspiration cytology (10%). The median size of the cyst was 25 (2-60) mm. Patients mainly presented with an asymptomatic midline neck mass at or below the hyoid bone (82%), followed by fistula (9%), infection (2%), and dysphagia (2%). Eighty-nine cases were identified preoperatively as TDC. The histopathological findings confirmed TDC with hyoid bone in 61 cases, and TDC alone in 38 cases. Eighty patients underwent the Sistrunk procedure while excision of TDC alone was observed in 18 cases. Five cases of recurrent disease were also treated. Adults had a greater median cyst size (30 (9-60) vs. 22 (2-55) mm; p = 0.005) and required prolonged operation time (69 (1-169) vs. 32.5 (1-140) mins;  p = 0.004) compared to the pediatric group.
  
  
  CONCLUSIONS
  The occurrence of TDC shows a bimodal age distribution. Preoperative evaluation and time for surgery vary whereas clinical presentations, surgical management, and postoperative outcomes are comparable among adult and pediatric groups. Ultrasonography is the preferred diagnostic modality, and the Sistrunk procedure remains the primary choice of treatment.
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Hassan
authors.initials: H
authors.lastname: Al-Thani
authors.affiliation: Clinical Research, Trauma Surgery Section, Hamad Medical Corporation, Doha, Qatar; Clinical Medicine, Weill Cornell Medical College, Doha, Qatar.
authors.forename: Ayman
authors.initials: A
authors.lastname: El-Menyar
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Maryam Al
authors.initials: MA
authors.lastname: Sulaiti
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Jamela
authors.initials: J
authors.lastname: El-Mabrok
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Khairi
authors.initials: K
authors.lastname: Hajaji
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Hesham
authors.initials: H
authors.lastname: Elgohary
authors.affiliation: Clinical Research, Trauma Surgery Section, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Mohammad
authors.initials: M
authors.lastname: Asim
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Taha
authors.affiliation: Department of Surgery, Hamad Medical Corporation, Doha, Qatar.
authors.forename: Abdelhakem
authors.initials: A
authors.lastname: Tabeb
keywords: Adults; Pediatrics; Sistrunk, Neck; Thyroglossal Duct Cyst