title: Recent advances in molecular genetics of melanoma progression: implications for diagnosis and treatment.
abstract: According to the multi-step carcinogenesis model of cancer, initiation results in a benign tumor and subsequent genetic alterations lead to tumor progression and the acquisition of the hallmarks of cancer. This article will review recent discoveries in our understanding of initiation and progression in melanocytic neoplasia and the impact on diagnostic dermatopathology.
authors.affiliation: Department of Dermatology, University of California San Francisco, San Francisco, CA, USA.
authors.forename: Iwei
authors.initials: I
authors.lastname: Yeh
keywords: BRAF; BRAFV600E; Spitz nevi; dermatopathology; melanocytic neoplasia; melanoma; nevi