title: Acetylome analysis reveals the involvement of lysine acetylation in diverse biological processes in Phytophthora sojae.
abstract: Lysine acetylation is a dynamic and highly conserved post-translational modification that plays an important regulatory role in almost every aspects of cell metabolism in both eukaryotes and prokaryotes. Phytophthora sojae is one of the most important plant pathogens due to its huge economic impact. However, to date, little is known about the functions of lysine acetylation in this Phytopthora. Here, we conducted a lysine acetylome in P. sojae. Overall, 2197 lysine acetylation sites in 1150 proteins were identified. The modified proteins are involved in diverse biological processes and are localized to multiple cellular compartments. Importantly, 7 proteins involved in the pathogenicity or the secretion pathway of P. sojae were found to be acetylated. These data provide the first comprehensive view of the acetylome of P. sojae and serve as an important resource for functional analysis of lysine acetylation in plant pathogens.
authors.affiliation: The Key Laboratory of Integrated Crop Pest Management of Shandong Province, College of Agronomy and Plant Protection, Qingdao Agricultural University, Qingdao 266109, China.
authors.forename: Delong
authors.initials: D
authors.lastname: Li
authors.affiliation: The Key Laboratory of Integrated Crop Pest Management of Shandong Province, College of Agronomy and Plant Protection, Qingdao Agricultural University, Qingdao 266109, China.
authors.forename: Binna
authors.initials: B
authors.lastname: Lv
authors.affiliation: College of Life Sciences, Qingdao Agricultural University, Qingdao 266109, China.
authors.forename: Lingling
authors.initials: L
authors.lastname: Tan
authors.affiliation: The Key Laboratory of Integrated Crop Pest Management of Shandong Province, College of Agronomy and Plant Protection, Qingdao Agricultural University, Qingdao 266109, China.
authors.forename: Qianqian
authors.initials: Q
authors.lastname: Yang
authors.affiliation: The Key Laboratory of Integrated Crop Pest Management of Shandong Province, College of Agronomy and Plant Protection, Qingdao Agricultural University, Qingdao 266109, China.
authors.forename: Wenxing
authors.initials: W
authors.lastname: Liang
mesh_terms: D000107:Acetylation; D000595:Amino Acid Sequence; D063990:Gene Ontology; D053263:Gene Regulatory Networks; D008239:Lysine / Q000378:metabolism*; D058977:Molecular Sequence Annotation; D025282:Mycelium / Q000235:genetics / Q000378:metabolism*; D010838:Phytophthora / Q000235:genetics / Q000378:metabolism* / Q000472:pathogenicity*; D010935:Plant Diseases / Q000382:microbiology; D010944:Plants / Q000382:microbiology; D025941:Protein Interaction Mapping; D011499:Protein Processing, Post-Translational; D020543:Proteome / Q000235:genetics / Q000378:metabolism*; D014774:Virulence
chemical_list: D020543:Proteome; D008239:Lysine