title: BCG-osis following intravesical BCG treatment leading to miliary pulmonary nodules, penile granulomas and a mycotic aortic aneurysm.
abstract: A 69-year-old male patient who was treated with intravesical BCG for carcinoma in situ of the bladder, went on to develop systemic features of BCG-osis. This diagnosis was supported by significant radiological and clinical findings. These systemic features include pulmonary miliary lesions, a mycotic abdominal aortic aneurysm and penile lesions. Owing to a breakdown in the relationship between the patient and the National Health Service, the patient has declined BCG treatment. This case highlights the potential rare side effects of intravesical BCG treatment and the risk associated with non-treatment of BCG-osis.
authors.affiliation: Leeds Teaching Hospitals NHS Trust, Leeds, UK.
authors.forename: David Mark
authors.initials: DM
authors.lastname: Smith
mesh_terms: D000283:Administration, Intravesical; D000368:Aged; D000785:Aneurysm, Infected / Q000209:etiology; D000818:Animals; D017544:Aortic Aneurysm, Abdominal / Q000382:microbiology*; D001500:BCG Vaccine / Q000009:adverse effects* / Q000627:therapeutic use; D002278:Carcinoma in Situ / Q000188:drug therapy; D002417:Cattle; D006099:Granuloma / Q000382:microbiology*; D006801:Humans; D008297:Male; D055613:Multiple Pulmonary Nodules / Q000382:microbiology*; D010409:Penile Diseases / Q000382:microbiology*; D014380:Tuberculosis, Bovine / Q000209:etiology*; D014391:Tuberculosis, Miliary / Q000382:microbiology*; D001749:Urinary Bladder Neoplasms / Q000188:drug therapy
chemical_list: D001500:BCG Vaccine