title: Synthesis of graphene and related two-dimensional materials for bioelectronics devices.
abstract: In recent years, graphene and related two-dimensional (2D) materials have emerged as exotic materials in nearly every fields of fundamental science and applied engineering. The latest progress has shown that these 2D materials could have a profound impact on bioelectronics devices. For the construction of these bioelectronics devices, these 2D materials were generally synthesized by the processes of exfoliation and chemical vapor deposition. In particular, the macrostructures of these 2D materials have also been realized by these two processes, which have shown great potentials in the self-supported and special-purpose biosensors. Due to the high specific surface area, subtle electron properties, abundant surface atoms of these 2D materials, the as-constructed bioelectronics devices have exhibited enhanced performance in the sensing of small biomolecules, heavy metals, pH, protein and DNA. The aim of this review article is to provide a comprehensive scientific progress in the synthesis of 2D materials for the construction of five typical bioelectronics devices (electrochemical biosensors, FET-based biosensors, piezoelectric devices, electrochemiluminescence devices and supercapacitors) and to overview the present status and future perspective of the applications of these bioelectronics devices based on 2D materials.
authors.affiliation: College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, PR China.
authors.forename: Tao
authors.initials: T
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, PR China.
authors.forename: Jilun
authors.initials: J
authors.lastname: Liu
authors.affiliation: College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, PR China.
authors.forename: Cheng
authors.initials: C
authors.lastname: Wang
authors.affiliation: College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, PR China.
authors.forename: Xuanye
authors.initials: X
authors.lastname: Leng
authors.affiliation: College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, PR China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Xiao
authors.affiliation: College of Chemistry and Molecular Science, Wuhan University, Wuhan 430072, PR China. Electronic address: leifu@whu.edu.cn.
authors.forename: Lei
authors.initials: L
authors.lastname: Fu
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D055664:Electrochemical Techniques / Q000295:instrumentation / Q000379:methods*; D004581:Electronics / Q000295:instrumentation / Q000379:methods*; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D008958:Models, Molecular; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*
chemical_list: D006108:Graphite
keywords: Bioelectronics devices; Graphene; Two-dimensional materials