title: Iron mobilization from ultraviolet-irradiated, iron-saturated, transferrin.
abstract: Transferrin is the major iron transport protein of mammalian plasma. The ultraviolet-B irradiation of 1.4 mg/ml iron saturated transferrin solutions (~32 μM Fe(3+)) induces a Fe(3+) loss accompanied by Fe(2+) formation. The initial quantum yield of Fe(3+) loss is wavelength dependent (φ(313 nm)~1.3×10(-3)) and oxygen independent suggesting an intramolecular electron transfer from one of the Fe(3+) ligands. A photolysis of tryptophan residues parallels this photoreduction.
authors.affiliation: a Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), Paris , France.
authors.forename: M
authors.initials: M
authors.lastname: Aubailly
authors.affiliation: a Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), Paris , France.
authors.forename: S
authors.initials: S
authors.lastname: Salmon
authors.affiliation: a Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), Paris , France.
authors.forename: P
authors.initials: P
authors.lastname: Morlière
authors.affiliation: a Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), Paris , France.
authors.forename: J
authors.initials: J
authors.lastname: Haigle
authors.affiliation: a Muséum National d'Histoire Naturelle, Laboratoire de Physico-Chimie de l'Adaptation Biologique (INSERM U 312), Paris , France.
authors.forename: R
authors.initials: R
authors.lastname: Santus