title: Surgical outcomes, bowel habits and quality of life in young patients after ileoanal anastomosis for ulcerative colitis.
abstract: OBJECTIVE
  We aim to investigate the postoperative outcomes, bowel habits and quality of life (QoL) of younger pediatric ulcerative colitis (UC) patients following surgical intervention compared to an older pediatric population.
  
  
  METHODS
  Medical records of UC patients after colectomy with ileoanal reconstruction (2002-2013) at our institution were reviewed. Patients/parents completed a QoL, bowel habits and disease course questionnaire. Surgical outcomes, bowel habits and QoL were reported comparing the younger (≤11years old, n=26) to older (>11years old, n=38) cohorts.
  
  
  RESULTS
  The mean age at colectomy was 7.04±0.63years vs 14.71±0.32years in the two groups. Patients had a significant (P<0.001) reduction in stooling frequency after surgery in both age groups and had favorable rates of fecal continence. The frequency of pouchitis and postoperative small bowel obstruction was similar in both cohorts. Dehydration was slightly increased in the younger population but not significant. Anastomotic leak and stricture rates were slightly reduced in younger patients. Postoperative QoL was favorable and similar regardless of age at surgery.
  
  
  CONCLUSIONS
  Colectomy with ileoanal anastomosis for young children (≤11years old) with UC is without increased complications relative to older patients and maintains a postoperative QoL and stool patterns.
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: J Leslie
authors.initials: JL
authors.lastname: Knod
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Monica
authors.initials: M
authors.lastname: Holder
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Alexander R
authors.initials: AR
authors.lastname: Cortez
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Bruno
authors.initials: B
authors.lastname: Martinez-Leo
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Patricia
authors.initials: P
authors.lastname: Kern
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Shehzad
authors.initials: S
authors.lastname: Saeed
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Brad
authors.initials: B
authors.lastname: Warner
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Belinda
authors.initials: B
authors.lastname: Dickie
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Richard A
authors.initials: RA
authors.lastname: Falcone
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA.
authors.forename: Daniel
authors.initials: D
authors.lastname: von Allmen
authors.affiliation: Cincinnati Children's Hospital Medical Center, 3333 Burnett Avenue, MLC-2023, Cincinnati, OH 45229, USA. Electronic address: Jason.Frischer@cchmc.org.
authors.forename: Jason S
authors.initials: JS
authors.lastname: Frischer
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D003093:Colitis, Ulcerative / Q000503:physiopathology / Q000601:surgery*; D003672:Defecation / Q000502:physiology; D005260:Female; D005500:Follow-Up Studies; D006305:Health Status Indicators; D006801:Humans; D008297:Male; D011183:Postoperative Complications / Q000453:epidemiology / Q000209:etiology*; D016737:Proctocolectomy, Restorative; D011788:Quality of Life; D012189:Retrospective Studies; D012307:Risk Factors; D011795:Surveys and Questionnaires; D016896:Treatment Outcome
keywords: ileoanal pouch anastomosis; outcomes; pediatric ulcerative colitis; quality of life; stooling habits