title: Ginsenoside Re improves skin barrier function in HaCaT keratinocytes under normal growth conditions.
abstract: Ginsenoside Re (Re), a major ginsenoside of ginseng, enhanced the cornified cell envelope (CE) formation in HaCaT keratinocytes under normal conditions. In HaCaT keratinocytes, Re was also able to upregulate filaggrin protein and caspase-14 activity in a concentration-dependent manner. These findings reasonably imply that Re possesses a desirable property of improving skin barrier function.
authors.affiliation: a Department of Biological Sciences , Kangwon National University , Chuncheon , Korea.
authors.forename: Yuri
authors.initials: Y
authors.lastname: Oh
authors.affiliation: b Shebah Biotech Inc. , Chuncheon , Korea.
authors.forename: Hye-Won
authors.initials: HW
authors.lastname: Lim
authors.affiliation: a Department of Biological Sciences , Kangwon National University , Chuncheon , Korea.
authors.forename: Kyunghoon
authors.initials: K
authors.lastname: Kim
authors.affiliation: b Shebah Biotech Inc. , Chuncheon , Korea.|c Department of Biochemistry , Kangwon National University , Chuncheon , Korea.
authors.forename: Chang-Jin
authors.initials: CJ
authors.lastname: Lim
keywords: HaCaT; caspase-14; cornified cell envelope; filaggrin; ginsenoside Re