title: Schwannoma Showing Avid Uptake on 68Ga-PSMA-HBED-CC PET/CT.
abstract: Ga prostate-specific membrane antigen (PSMA) PET/CT is a relatively new and highly sensitive imaging modality used in staging metastatic prostate cancer. We report a case of a 65-year-old man with newly diagnosed prostate carcinoma who had a PSMA PET/CT scan for staging of his disease. A PSMA-avid right pelvic mass was identified anterior to the sacrum. Surgical removal and histopathological examination of this lesion revealed the diagnosis of schwannoma. It is important to be aware that schwannoma may also show avid uptake on PSMA PET/CT scan and may potentially lead to an incorrect diagnosis of metastatic prostate carcinoma.
authors.affiliation: From the *Department of Nuclear Medicine, Royal North Shore Hospital; †The University of New South Wales, Sydney; ‡Genesis Cancer Care, Mater Hospital, North Sydney; §The University of Sydney; ∥Department of Nuclear Medicine, St Vincent's Hospital, Sydney, Australia.
authors.forename: Gowri L
authors.initials: GL
authors.lastname: Kanthan
authors.forename: Michael A
authors.initials: MA
authors.lastname: Izard
authors.forename: Louise
authors.initials: L
authors.lastname: Emmett
authors.forename: Edward
authors.initials: E
authors.lastname: Hsiao
authors.forename: Geoffrey Paul
authors.initials: GP
authors.lastname: Schembri
mesh_terms: D000368:Aged; D000954:Antigens, Surface / Q000378:metabolism; D003937:Diagnosis, Differential; D004492:Edetic Acid / Q000031:analogs & derivatives; D005709:Gallium Isotopes; D005710:Gallium Radioisotopes; D043425:Glutamate Carboxypeptidase II / Q000378:metabolism; D006801:Humans; D008297:Male; D009442:Neurilemmoma / Q000000981:diagnostic imaging*; D009842:Oligopeptides; D009942:Organometallic Compounds; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods; D011471:Prostatic Neoplasms / Q000000981:diagnostic imaging*
chemical_list: D000954:Antigens, Surface; D005709:Gallium Isotopes; D005710:Gallium Radioisotopes; D009842:Oligopeptides; D009942:Organometallic Compounds; C000718244:gallium 68 PSMA-11; D004492:Edetic Acid; C473848:FOLH1 protein, human; D043425:Glutamate Carboxypeptidase II