title: Treatment of Paecilomyces variotii pneumonia with posaconazole: case report and literature review.
abstract: The fungi Paecilomyces variotii is a potential pathogen in immunocompromised and immunocompetent patients. Their rare association with clinical disease results in scarce literature regarding susceptibility and treatment. Here, we discuss a case involving successful treatment of probable P. variotii pneumonia with posaconazole after treatment failure with voriconazole. The current literature related to antifungal susceptibility profiles, microbiological identification methods and clinical management of infections caused by this organism is also reviewed.
authors.affiliation: Department of Pharmacy, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Ryan
authors.initials: R
authors.lastname: Feldman
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Leslie
authors.initials: L
authors.lastname: Cockerham
authors.affiliation: Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Blake W
authors.initials: BW
authors.lastname: Buchan
authors.affiliation: Division of Infectious Diseases, Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Zouyan
authors.initials: Z
authors.lastname: Lu
authors.affiliation: Department of Pharmacy, Froedtert & The Medical College of Wisconsin, Milwaukee, WI, USA.
authors.forename: Angela M
authors.initials: AM
authors.lastname: Huang
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008875:Middle Aged; D009181:Mycoses / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D010143:Paecilomyces / Q000187:drug effects* / Q000235:genetics / Q000502:physiology; D011014:Pneumonia / Q000000981:diagnostic imaging / Q000188:drug therapy* / Q000382:microbiology; D014230:Triazoles / Q000627:therapeutic use*
chemical_list: D000935:Antifungal Agents; D014230:Triazoles; C101425:posaconazole
keywords: 
  Paecilomyces variotii
  ; pneumonia; posaconazole