title: [Assessment of risk of sudden cardiac death in patients with hypertrophic cardiomyopathy].
abstract: Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterized by left ventricular hypertrophy with or without concomitant outflow tract obstruction. Identification of patients with HCM who are at high risk of sudden cardiac death (SCD) is crucial as those patients are likely to benefit from an implantable cardioverter defibrillator (ICD). Based on the HCM Risk-SCD study published in 2013, that included 3675 HCM patients with 24 313 years of follow up, a new clinical risk prediction model for sudden cardiac death was developed. This model was included in the recently released 2014 ESC guidelines. This review summarizes the changes in the prediction model and the resulting recommendations and discusses potential risks and limitations of the new score.
authors.forename: Philipp
authors.initials: P
authors.lastname: Attanasio
authors.forename: Florian
authors.initials: F
authors.lastname: Blaschke
authors.forename: Burkert
authors.initials: B
authors.lastname: Pieske
authors.forename: Carsten
authors.initials: C
authors.lastname: Tschöpe
authors.forename: Wilhelm
authors.initials: W
authors.lastname: Haverkamp
mesh_terms: D000293:Adolescent; D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D002312:Cardiomyopathy, Hypertrophic / Q000175:diagnosis / Q000401:mortality* / Q000628:therapy; D015984:Causality; D015897:Comorbidity; D016757:Death, Sudden, Cardiac / Q000453:epidemiology* / Q000517:prevention & control; D005060:Europe / Q000453:epidemiology; D006801:Humans; D008875:Middle Aged; D015995:Prevalence; D016016:Proportional Hazards Models; D015203:Reproducibility of Results; D018570:Risk Assessment / Q000379:methods*; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D015996:Survival Rate; D055815:Young Adult