title: Mean Platelet Volume in Mycobacterium tuberculosis Infection.
abstract: Introduction. Mean platelet volume (MPV) has been thought as a useful index of platelet activation. It is supposed that MPV is also associated with several inflammatory and infectious diseases. Korea still has a high incidence of tuberculosis (TB). The aim of this study was to investigate MPV as an inflammatory marker in TB patients. Materials and Methods. MPV were determined in 221 patients with TB and 143 individuals for control group. MPV was estimated by an Advia 2120 (Siemens Healthcare Diagnostics, Tarrytown, NY, USA). Results. In the TB patient group, a positive correlation was found between CRP and MPV. Age and MPV had a positive correlation in TB patient group. Conclusions. We conclude that there is a significant relation between MPV and inflammatory conditions. MPV can be an inflammatory marker to determine the disease activity in TB patients.
authors.affiliation: Department of Laboratory Medicine, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea; Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
authors.forename: Min Young
authors.initials: MY
authors.lastname: Lee
authors.affiliation: Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
authors.forename: Young Jin
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
authors.forename: Hee Joo
authors.initials: HJ
authors.lastname: Lee
authors.affiliation: Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
authors.forename: Sun Young
authors.identifier: 0000-0002-3208-5446
authors.initials: SY
authors.lastname: Cho
authors.affiliation: Department of Laboratory Medicine, School of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
authors.forename: Tae Sung
authors.initials: TS
authors.lastname: Park
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D063847:Mean Platelet Volume / Q000706:statistics & numerical data*; D008875:Middle Aged; D009169:Mycobacterium tuberculosis; D015995:Prevalence; D015203:Reproducibility of Results; D056910:Republic of Korea / Q000453:epidemiology; D012307:Risk Factors; D012680:Sensitivity and Specificity; D014376:Tuberculosis / Q000097:blood* / Q000175:diagnosis* / Q000453:epidemiology; D055815:Young Adult