title: Antimicrobial Resistance and Neisseria gonorrhoeae Multiantigen Sequence Typing Profile of Neisseria gonorrhoeae in New Delhi, India.
abstract: Molecular epidemiology of 100 consecutive gonococcal isolates collected between April 2010 and October 2013 from New Delhi was investigated using Neisseria gonorrhoeae multiantigen sequence typing (NG-MAST) along with its association with antimicrobial resistance profiles. Neisseria gonorrhoeae isolates were assigned into 60 different sequence types and 43 (71.6%) were novel. Sole representation was seen in 76.6% sequence types. There was significant association between ST6058 and resistance to penicillin (P = 0.00) and tetracycline (P = 0.002).
authors.affiliation: From the *Department of Microbiology; †Department of Biostatistics, All India Institute of Medical Sciences; ‡Department of Dermatology, STDs and Leprosy, PGIMER and Dr Ram Manohar Lohia Hospital; and §Department of Dermatology and Venereology, All India Institute of Medical Sciences, New Delhi, India.
authors.forename: Neeraj
authors.initials: N
authors.lastname: Mahajan
authors.forename: Seema
authors.initials: S
authors.lastname: Sood
authors.forename: Rajendra
authors.initials: R
authors.lastname: Singh
authors.forename: Arti
authors.initials: A
authors.lastname: Kapil
authors.forename: Bimal Kumar
authors.initials: BK
authors.lastname: Das
authors.forename: Vishnubhatla
authors.initials: V
authors.lastname: Sreenivas
authors.forename: Hemanta Kumar
authors.initials: HK
authors.lastname: Kar
authors.forename: Vinod Kumar
authors.initials: VK
authors.lastname: Sharma
mesh_terms: D000293:Adolescent; D000328:Adult; D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D015373:Bacterial Typing Techniques; D005260:Female; D006069:Gonorrhea / Q000188:drug therapy / Q000453:epidemiology* / Q000382:microbiology; D006801:Humans; D007194:India / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D017720:Molecular Epidemiology; D058885:Multilocus Sequence Typing; D009344:Neisseria gonorrhoeae / Q000145:classification* / Q000187:drug effects / Q000235:genetics; D010406:Penicillins / Q000494:pharmacology; D017422:Sequence Analysis, DNA; D013752:Tetracycline / Q000494:pharmacology; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D010406:Penicillins; D013752:Tetracycline