title: Translation, Adaptation and Initial Validation of Food Allergy Quality of Life Questionnaire: Child form in Greek.
abstract: The aim of the study is to determine the reliability and validity of the Greek version of the Food Allergy Quality of life Questionnaire-Child Form (FAQLQ-CF). After linguistic validation, the Greek FAQLQ-CF, Food Allergy Independent Measure (FAIM) and Pediatric Quality of Life Inventory (PedsQL™) were used by a physician to interview children diagnosed with food allergy and aged 8-12 via telephone. Cronbach's alpha was used to evaluate reliability, and factor analysis to assess construct validity. The correlation between FAQLQ-CF and FAIM was moderate (rho=0.509, P<0.001) and internal consistency was strong (Cronbach's alpha 0.905). FAQLQ-CF discriminated well each question's contribution to children's quality of life deterioration (32-80%), each child's quality of life (17-89%), children differing in doing things with others (total score 3.55 vs 2.57, difference =0.98 > minimal clinical importance difference = 0.5; P<0.001), but not children differing in reporting anaphylaxis. The total FAQLQ-CF score correlated with the total PedsQL™ score and with the score of one of PedsQL™ subscales, demonstrating convergent validity. Factor analysis uncovered an underlying structure of four factors, explaining 50% of the variance. We can conclude that Greek FAQLQ-CF is a reliable, valid, discriminant tool for interviewing food allergic children aged 8-12, detecting those in need for immediate care.
authors.affiliation: Department of Hygiene and Epidemiology, University of Ioannina Medical School , Ioannina, Greece.
authors.forename: Zoe
authors.initials: Z
authors.lastname: Morou
authors.affiliation: Second Department of Anesthesiology, University of Athens Medical School , Athens, Greece.
authors.forename: Georgios N
authors.initials: GN
authors.lastname: Lyrakos
authors.affiliation: Allergy Department, 2nd Pediatric Clinic, University of Athens , Greece.
authors.forename: Nikolaos G
authors.initials: NG
authors.lastname: Papadopoulos
authors.affiliation: Allergy Department, 2nd Pediatric Clinic, University of Athens , Greece.
authors.forename: Nikolaos
authors.initials: N
authors.lastname: Douladiris
authors.affiliation: Tufts University School of Medicine, Boston, MA, USA; Department of Internal Medicine, University of Ioannina Medical School, loannina Greece.
authors.forename: Athina
authors.initials: A
authors.lastname: Tatsioni
authors.affiliation: Department of Hygiene and Epidemiology, University of Ioannina Medical School , Ioannina, Greece.
authors.forename: Ioannis D K
authors.initials: ID
authors.lastname: Dimoliatis
keywords: Child; food hypersensitivity; quality of life; questionnaires; validation