title: Interplay between Clinical Guidelines and Organizational Workflow Systems. Experience from the MobiGuide Project.
abstract: BACKGROUND
  Implementing a decision-support system within a healthcare organization requires integration of clinical domain knowledge with resource constraints. Computer-interpretable guidelines (CIG) are excellent instruments for addressing clinical aspects while business process management (BPM) languages and Workflow (Wf) engines manage the logistic organizational constraints.
  
  
  OBJECTIVE
  Our objective is the orchestration of all the relevant factors needed for a successful execution of patient's care pathways, especially when spanning the continuum of care, from acute to community or home care.
  
  
  METHODS
  We considered three strategies for integrating CIGs with organizational workflows: extending the CIG or BPM languages and their engines, or creating an interplay between them. We used the interplay approach to implement a set of use cases arising from a CIG implementation in the domain of Atrial Fibrillation. To provide a more scalable and standards-based solution, we explored the use of Cross-Enterprise Document Workflow Integration Profile.
  
  
  RESULTS
  We describe our proof-of-concept implementation of five use cases. We utilized the Personal Health Record of the MobiGuide project to implement a loosely-coupled approach between the Activiti BPM engine and the Picard CIG engine. Changes in the PHR were detected by polling. IHE profiles were used to develop workflow documents that orchestrate cross-enterprise execution of cardioversion.
  
  
  CONCLUSIONS
  Interplay between CIG and BPM engines can support orchestration of care flows within organizational settings.
authors.forename: Amnon
authors.initials: A
authors.lastname: Shabo
authors.affiliation: Mor Peleg, University of Haifa, Department of Information Systems, Rabin Building, room 7047, Haifa, 3498838, Israel, E-mail: morpeleg@is.haifa.ac.il.
authors.forename: Mor
authors.initials: M
authors.lastname: Peleg
authors.forename: Enea
authors.initials: E
authors.lastname: Parimbelli
authors.forename: Silvana
authors.initials: S
authors.lastname: Quaglini
authors.forename: Carlo
authors.initials: C
authors.lastname: Napolitano
mesh_terms: D004554:Electric Countershock; D005260:Female; D006801:Humans; D033181:Information Dissemination; D017410:Practice Guidelines as Topic; D057188:Workflow
keywords: Clinical guidelines; business processes; computer-interpretable guidelines; interoperability standards; workflow management systems