title: Evaluation of the Safety and Effectiveness of Intense Pulsed Light in the Treatment of Meibomian Gland Dysfunction.
abstract: Purpose. This study aims to explore the safety and efficacy of a novel treatment-intense pulsed light (IPL) in MGD eyes. Methods. This study is a prospective and open label study. Forty eyes of 40 MGD patients were recruited in the study and received 4 consecutive IPL treatments on day 1, day 15, day 45, and day 75. Ten ocular surface symptoms were evaluated with a subjective face score at every visit. Best spectacle corrected visual acuity, intraocular pressure (IOP), conjunctival injection, upper and lower tear meniscus height (TMH), tear break-up time (TBUT), corneal staining, lid margin and meibomian gland assessments, and meibography were also recorded at every visit, as well as the adverse effects on the eye and ocular surface. Results. Significant improvements were observed in single and total ocular surface symptom scores, TBUT, and conjunctival injection at all the visits after the initial IPL treatment (P < 0.05). Compared to baseline, the signs of eyelid margin, meibomian gland secretion quality, and expressibility were significantly improved at every visit after treatments. There was no regional and systemic threat observed in any patient. Conclusion. Intense pulsed light (IPL) therapy is a safe and efficient treatment in relieving symptoms and signs of MGD eyes.
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Xiaodan
authors.identifier: 0000-0003-2448-4815
authors.initials: X
authors.lastname: Jiang
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Huibin
authors.initials: H
authors.lastname: Lv
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Hang
authors.identifier: 0000-0002-0234-6801
authors.initials: H
authors.lastname: Song
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Mingzhou
authors.identifier: 0000-0003-1807-0958
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Xiaodan
authors.identifier: 0000-0001-8894-6623
authors.initials: X
authors.lastname: Hu
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Xuemin
authors.identifier: 0000-0002-4018-9974
authors.initials: X
authors.lastname: Li
authors.affiliation: Ophthalmology Department, Peking University Third Hospital, Beijing 100191, China.
authors.forename: Wei
authors.initials: W
authors.lastname: Wang