title: The Efficacy of Low Molecular Weight Heparin for the Prevention of Venous Thromboembolism after Hip Fracture Surgery in Korean Patients.
abstract: OBJECTIVE
  The aim of this study was to investigate the efficacy of low-molecular-weight heparin (LMWH) for the prevention of venous thromboembolism in Korean patients who underwent hip fracture surgery (HFS).
  
  
  METHODS
  Prospectively, a total 181 cases were classified into the LMWH user group (116 cases) and LMWH non-user group (65 cases). Each group was sub-classified according to fracture types as follows: 81 cases of intertrochanteric fracture (group A: 49, group B: 32) and 100 cases of neck fracture (group C: 67, group D: 33). We compared the incidence of deep vein thrombosis (DVT) and pulmonary embolism (PE) according to LMWH use.
  
  
  RESULTS
  Of the 181 cases, four DVTs were found in the LMWH user groups (1 in group A, and 3 in group C). One case of PE was found in LMWH non-user group D. The incidences of DVT and PE showed no statistically significant differences between the LMWH user and non-user groups (p=0.298 and 0.359, respectively). In subgroup analysis, no statistically significant differences were found between groups A and B and between groups C and D.
  
  
  CONCLUSIONS
  The administration of LMWH was not effective in the prevention of venous thromboembolism and PE in the Korean patients who underwent HFS.
authors.affiliation: Department of Orthopedic Surgery, Stanford University College of Medicine (Visiting professor), Stanford, CA, USA.|Department of Orthopaedic Surgery, Konyang University School of Medicine, Deajeon, Korea.
authors.forename: Kwang Kyoun
authors.initials: KK
authors.lastname: Kim
authors.affiliation: Department of Orthopaedic Surgery, Konyang University School of Medicine, Deajeon, Korea.|Department of Orthopaedics, Graduate School of Medicine, Yonsei University, Seoul, Korea. yougunwon@gmail.com.
authors.forename: Yougun
authors.initials: Y
authors.lastname: Won
authors.affiliation: Department of Orthopaedic Surgery, Ajou University School of Medicine, Suwon, Korea.
authors.forename: Ye Yeon
authors.initials: YY
authors.lastname: Won
mesh_terms: D000368:Aged; D000925:Anticoagulants / Q000627:therapeutic use*; D005260:Female; D006495:Heparin, Low-Molecular-Weight / Q000627:therapeutic use*; D006620:Hip Fractures / Q000145:classification / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011183:Postoperative Complications / Q000517:prevention & control*; D011655:Pulmonary Embolism / Q000209:etiology / Q000517:prevention & control*; D056910:Republic of Korea; D054556:Venous Thromboembolism / Q000517:prevention & control*; D020246:Venous Thrombosis / Q000209:etiology / Q000517:prevention & control*
chemical_list: D000925:Anticoagulants; D006495:Heparin, Low-Molecular-Weight
keywords: Low molecular weight heparin; deep vein thrombosis; hip fracture; pulmonary embolism