title: Association of alcohol consumption with coronary artery disease severity.
abstract: The ingestion of small to moderate alcohol consumption amounts has been associated to cardiovascular protection. This study aimed to evaluate the association between alcohol consumption and coronary artery disease severity.
  
  
  
  Cross-sectional Study with patients undergoing coronary angiography. Age, cardiovascular risk factors (smoking, systemic arterial hypertension, dyslipidemia and diabetes) and alcohol drinking habit were investigated. Alcohol consumption was divided in three categories: nondrinker, moderate alcohol consumption (less than 15 g ethanol/day for women or 30 g ethanol/day for men) and heavy alcohol consumption. Coronary artery disease severity was assessed through the Friesinger Score (FS) in the coronary angiography, by interventional cardiologists blinded to alcohol consumption.
  
  
  
  The final sample included 363 adults; of those, 228 were men (62.81%). Mean age was 60.5 ± 10.9 y. Unadjusted analyses identified sex, age, hypertension, diabetes, dyslipidemia and alcohol consumption as the main covariates associated with the Friesinger score. Lower Friesinger scores were also observed in moderate alcohol consumption when comparing to those who do not drink (RR 0.86; 95% CI 0.79-0.95).
  
  
  
  Among patients with suspected coronary artery disease undergoing coronary angiography, moderate alcohol consumption is associated to a lower coronary artery disease severity than heavy drinking.
authors.affiliation: Department of Food and Nutrition, Universidade Federal de Santa Maria, Palmeira das Missões, Brazil; Program of Postgraduate in Gerontology, Universidade Federal de Santa Maria, Santa Maria, Brazil. Electronic address: patriciachagas.ufsm@hotmail.com.
authors.forename: Patricia
authors.initials: P
authors.lastname: Chagas
authors.affiliation: Program of Postgraduate in Gerontology, Universidade Federal de Santa Maria, Santa Maria, Brazil. Electronic address: lety.mazocco@gmail.com.
authors.forename: Leticia
authors.initials: L
authors.lastname: Mazocco
authors.affiliation: Program of Postgraduate in Pharmaceutical Sciences, Universidade Federal do Pampa, Uruguaiana, Brazil. Electronic address: jcepiccoli@yahoo.com.br.
authors.forename: Jacqueline da Costa Escobar
authors.initials: JDCE
authors.lastname: Piccoli
authors.affiliation: Department of Stomatology, Faculty of Dentistry, Universidade Federal de Santa Maria, Santa Maria, Brazil. Electronic address: thiardenghi@hotmail.com.
authors.forename: Thiago Machado
authors.initials: TM
authors.lastname: Ardenghi
authors.affiliation: Cardiovascular Research Center, CSIC-ICCC, Hospital de la Santa Creu i Sant Pau, IIB-Sant Pau, Barcelona, Spain; Cardiovascular Research Chair, UAB, Barcelona, Spain. Electronic address: lbadimon@csic-iccc.org.
authors.forename: Lina
authors.initials: L
authors.lastname: Badimon
authors.affiliation: Center for Cardiovascular Research, Hospital São Lucas-Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: caramori@cardiarte.com.br.
authors.forename: Paulo Ricardo Avancini
authors.initials: PRA
authors.lastname: Caramori
authors.affiliation: Fundação Universitária de Cardiologia, Universidade Federal de Ciências da Saúde, Porto Alegre, Brazil. Electronic address: lupellanda@gmail.com.
authors.forename: Lucia
authors.initials: L
authors.lastname: Pellanda
authors.affiliation: Institute of Geriatrics and Gerontology, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: irenio.filho@pucrs.br.
authors.forename: Irênio
authors.initials: I
authors.lastname: Gomes
authors.affiliation: Institute of Geriatrics and Gerontology, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil. Electronic address: schwanke@pucrs.br.
authors.forename: Carla Helena Augustin
authors.initials: CHA
authors.lastname: Schwanke
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D064829:Alcohol Abstinence; D000428:Alcohol Drinking / Q000009:adverse effects*; D000437:Alcoholism / Q000503:physiopathology*; D001938:Brazil / Q000453:epidemiology; D017023:Coronary Angiography; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000453:epidemiology / Q000209:etiology* / Q000503:physiopathology; D003331:Coronary Vessels / Q000000981:diagnostic imaging*; D003430:Cross-Sectional Studies; D005260:Female; D006786:Hospitals, Urban; D006801:Humans; D008297:Male; D008875:Middle Aged; D012307:Risk Factors; D057566:Self Report; D012720:Severity of Illness Index; D055815:Young Adult
keywords: Alcohol consumption; Coronary artery disease; Nutrition