title: Tissue Sculpting by Fibrils.
abstract: In this issue of Developmental Cell, Isabella and Horne-Badovinac (2016) show that Rab10 directs site-specific secretion of basement membrane components, which assemble into fibrils that spool out to elongate the Drosophila egg chamber. These findings establish the basement membrane's active role in tissue sculpting.
authors.affiliation: Department of Biology, Duke University, Durham, NC 27708, USA.
authors.forename: Ranjay
authors.initials: R
authors.lastname: Jayadev
authors.affiliation: Department of Biology, Duke University, Durham, NC 27708, USA. Electronic address: david.sherwood@duke.edu.
authors.forename: David R
authors.initials: DR
authors.lastname: Sherwood
mesh_terms: D000818:Animals; D001485:Basement Membrane / Q000378:metabolism*; D029721:Drosophila Proteins / Q000235:genetics / Q000378:metabolism*; D004331:Drosophila melanogaster / Q000235:genetics / Q000254:growth & development* / Q000378:metabolism; D020559:Monomeric GTP-Binding Proteins / Q000235:genetics / Q000378:metabolism*; D009024:Morphogenesis / Q000502:physiology*; D038081:Organogenesis / Q000502:physiology*
chemical_list: D029721:Drosophila Proteins; D020559:Monomeric GTP-Binding Proteins; C579344:Rab10 protein, Drosophila