title: Photocatalytic Systems with Flavinium Salts: From Photolyase Models to Synthetic Tool for Cyclobutane Ring Opening.
abstract: Two new photocatalytic systems based on flavinium species formed in situ by protonation of riboflavin-tetraacetate (1) with triflic acid or prepared in advance via alloxazine quaternization are presented as effective tools for oxidative cyclobutane ring [2 + 2] cycloreversion using visible light. The system with 1,3-dimethyl-8-trifluoromethylalloxazinium perchlorate (2c) was found to be superior allowing an acid-free mild procedure, which results in the opening of cyclobutanes with high oxidation potential (up to 2.14 V) and/or with sensitive groups (e.g., furan) without side reactions.
authors.affiliation: Department of Organic Chemistry, University of Chemistry and Technology, Prague , Technická 5, 166 28 Prague, Czech Republic.
authors.forename: Tomáš
authors.initials: T
authors.lastname: Hartman
authors.affiliation: Department of Organic Chemistry, University of Chemistry and Technology, Prague , Technická 5, 166 28 Prague, Czech Republic.
authors.forename: Radek
authors.initials: R
authors.lastname: Cibulka