title: Selective Oxytrifluoromethylation of Allylamines with CO2.
abstract: Reported is the first oxy-trifluoromethylation of allylamines with carbon dioxide (CO2 ) using copper catalysis, thus leading to important CF3 -containing 2-oxazolidones. It is also the first time CO2 , a nontoxic and easily available greenhouse gas, has been used to tune the difunctionalization of alkenes from amino- to oxy-trifluoromethylation. Of particular note, this multicomponent reaction is highly chemo-, regio-, and diastereoselective under redox-neutral and mild reaction conditions. Moreover, these reactions feature good functional-group tolerance, broad substrate scope, easy scalability and facile product diversification. The important products could also be formed with either spirocycles or two adjacent tetrasubstituted carbon centers.
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Jian-Heng
authors.identifier: 0000-0002-4932-0414
authors.initials: JH
authors.lastname: Ye
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Lei
authors.identifier: 0000-0003-2454-1576
authors.initials: L
authors.lastname: Song
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.|College of Chemistry and Chemical Engineering, Neijiang Normal University, Neijiang, 641112, P.R. China.
authors.forename: Wen-Jun
authors.identifier: 0000-0001-5933-4679
authors.initials: WJ
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Tao
authors.identifier: 0000-0003-0532-332X
authors.initials: T
authors.lastname: Ju
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Zhu-Bao
authors.identifier: 0000-0003-2200-3598
authors.initials: ZB
authors.lastname: Yin
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Si-Shun
authors.identifier: 0000-0002-9057-7318
authors.initials: SS
authors.lastname: Yan
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Zhen
authors.identifier: 0000-0002-3538-6519
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China.
authors.forename: Jing
authors.identifier: 0000-0003-1539-2521
authors.initials: J
authors.lastname: Li
authors.affiliation: Key Laboratory of Green Chemistry & Technology of Ministry of Education, College of Chemistry, Sichuan University, 29 Wangjiang Road, Chengdu, 610064, P.R. China. dgyu@scu.edu.cn.
authors.forename: Da-Gang
authors.identifier: 0000-0001-5888-1494
authors.initials: DG
authors.lastname: Yu
keywords: carbon dioxide; copper; fluorine; heterocycles; reaction mechanisms