title: The Troubled Touch of Autism.
abstract: A study finds that deficits in touch-sensing somatosensory neurons contribute to social interaction and anxiety phenotypes in mouse models of autism and Rett syndrome. These findings suggest that some core symptoms of autism might originate from aberrant development or function of the peripheral nervous system.
authors.affiliation: Department of Cell Biology and Physiology, UNC Neuroscience Center, The Carolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
authors.forename: Alexander H
authors.initials: AH
authors.lastname: Tuttle
authors.affiliation: Department of Cell Biology and Physiology, UNC Neuroscience Center, The Carolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
authors.forename: Victoria B
authors.initials: VB
authors.lastname: Bartsch
authors.affiliation: Department of Cell Biology and Physiology, UNC Neuroscience Center, The Carolina Institute for Developmental Disabilities, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. Electronic address: zylka@med.unc.edu.
authors.forename: Mark J
authors.initials: MJ
authors.lastname: Zylka
mesh_terms: D000818:Animals; D001321:Autistic Disorder / Q000235:genetics*; D004195:Disease Models, Animal; D051783:Methyl-CpG-Binding Protein 2 / Q000235:genetics*; D051379:Mice; D015518:Rett Syndrome / Q000235:genetics; D014110:Touch
chemical_list: D051783:Methyl-CpG-Binding Protein 2