title: [Vulvar squamous cell carcinoma in young women with HPV negative].
abstract: BACKGROUND
  The vulvar cancer is the fourth more frequent neoplasia after the endometrial, cervix and ovarian cancer. Normally, it has been related to old women of ages from 70 to 80 years old. Rarely, it has been detected cases in adult or young women. However, its incidence has been increased in the last years and in more early years. It is for this change in the incidence and its appearance in early years why a possible etiology has been looked for, opening different hypothesis that go from that related to the HPV to those that study an inflammatory chronic process as the basis for the carcinogenesis.
  
  
  METHODS
  In this article, it has been presented the case of a woman who is 34 years old with negative VPH that made her debut with epidermoid carcinoma of the vulva moderately different and on purpose of the case, we do a revision of the literature existent.
  
  
  CONCLUSIONS
  Vulvar cancer diagnosed in young women as in older, but with different trends, risk factors and natural history. The case reported here escapes the theories studied so far so needed new lines of inquiry to investigate this form of presentation young woman, without HPV infection.
authors.forename: A
authors.initials: A
authors.lastname: Gómez-Alarcon
authors.forename: M T
authors.initials: MT
authors.lastname: Gómez-García
authors.forename: J P
authors.initials: JP
authors.lastname: García-de la-Torre
authors.forename: M
authors.initials: M
authors.lastname: Del Valle-Morón
authors.forename: M A
authors.initials: MA
authors.lastname: Arones-Collantes
authors.forename: G
authors.initials: G
authors.lastname: González-de Merlo
mesh_terms: D000328:Adult; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery; D005260:Female; D006801:Humans; D030361:Papillomavirus Infections; D014846:Vulvar Neoplasms / Q000473:pathology / Q000601:surgery