title: [Unclear liver lesions in a 19-year-old woman with acute myeloid leukemia].
abstract: A 19-year old woman with acute myeloid leukemia presented with newly observed liver lesions during ongoing consolidation therapy. Due to unexplained cholestasis during induction, biliary duct drainage was performed. Microbiologic and histologic examinations revealed the presence of atypical mycobacteria, namely Mycobacterium abscessus. With an appropriate antiinfective regime which was continuously administered using a portable pump in the outpatient setting, further mycobacterial spread during simultaneous chemotherapy-associated neutropenia was prevented. Despite multiple bacterial resistance mechanisms, proper treatment of leukemia with curative intention could be ensured.
authors.affiliation: Klinik für Onkologie und Hämatologie, Krankenhaus Barmherzige Brüder Regensburg, Prüfeningerstr. 86, 93049, Regensburg, Deutschland. bernhard.braun@barmherzige-regensburg.de.
authors.forename: B
authors.initials: B
authors.lastname: Braun
authors.affiliation: Klinik für Gastroenterologie und interventionelle Endoskopie, Krankenhaus Barmherzige Brüder Regensburg, Regensburg, Deutschland.
authors.forename: A P
authors.initials: AP
authors.lastname: Karl
authors.affiliation: Klinik für Gastroenterologie und interventionelle Endoskopie, Krankenhaus Barmherzige Brüder Regensburg, Regensburg, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Dierkes
authors.affiliation: Klinik für Onkologie und Hämatologie, Krankenhaus Barmherzige Brüder Regensburg, Prüfeningerstr. 86, 93049, Regensburg, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Schenk
authors.affiliation: Klinik für Onkologie und Hämatologie, Krankenhaus Barmherzige Brüder Regensburg, Prüfeningerstr. 86, 93049, Regensburg, Deutschland.
authors.forename: J
authors.initials: J
authors.lastname: Braess
mesh_terms: D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D000970:Antineoplastic Agents / Q000009:adverse effects* / Q000627:therapeutic use; D056486:Chemical and Drug Induced Liver Injury / Q000175:diagnosis / Q000188:drug therapy* / Q000209:etiology / Q000382:microbiology; D003937:Diagnosis, Differential; D005260:Female; D006505:Hepatitis; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000150:complications / Q000188:drug therapy* / Q000382:microbiology; D009164:Mycobacterium Infections / Q000139:chemically induced* / Q000175:diagnosis / Q000188:drug therapy*; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D000900:Anti-Bacterial Agents; D000970:Antineoplastic Agents
keywords: Atypical mycobacteria; Drug resistance, multiple; Leukemia, myeloid, acute; Liver lesions; Mycobacterium abscessus