title: Comparison of 1800 Robotic and Open Partial Nephrectomies for Renal Tumors.
abstract: Only a few studies have compared the outcomes of robotic partial nephrectomy (RPN) and open partial nephrectomy (OPN). This study aimed to compare perioperative and oncologic outcomes of RPN and OPN.
  
  
  
  The data of all patients who underwent partial nephrectomy from 2006 to 2014 in six academic departments of urology were retrospectively collected. Perioperative outcomes were compared between OPN and RPN patients. Cancer-specific survival (CSS) and recurrence-free survival (RFS) were estimated using the Kaplan-Meier method and compared using the log-rank test.
  
  
  
  The study included 1800 patients: 937 who underwent RPN and 863 who underwent OPN. The patients in the robotic group had smaller tumors (33.1 vs. 39.9 mm; p < 0.001) but comparable RENAL scores (6.8 vs. 6.7; p = 0.37). The complication rate was higher in the OPN group (28.6 vs. 18 %; p < 0.001). The OPN patients had greater estimated blood loss (359.5 vs. 275 ml; p < 0.001) and more frequent hemorrhagic complications (12.1 vs. 6.9 %; p < 0.001). The robotic approach was associated with a shorter warm ischemia time (WIT 15.7 vs. 18.6 min; p < 0.001) and a shorter hospital of stay (4.7 vs. 10.1 days; p < 0.001). In the propensity score-weighted analysis, the inverse probability of treatment weighting adjusted odds ratio for the risk of complication after OPN versus RPN was 2.11 (95 % confidence interval, 1.53-2.91; p < 0.001). After a median postoperative follow-up period of 13 months for OPN and 39 months for RPN (p < 0.001), CSS and RFS were similar in the two groups. In the multivariate analysis, RPN showed an impact on the occurrence of a complication but had no effect on WIT or RFS.
  
  
  
  In this study, RPN was less morbid than OPN, with lower complications, less blood loss, and a shorter hospital of stay. The intermediate-term oncologic outcomes were similar in the two groups.
authors.affiliation: Department of Urology, Hopital Pontchaillou, CHU Rennes, Rennes, France. peyronnetbenoit@hotmail.fr.
authors.forename: Benoit
authors.initials: B
authors.lastname: Peyronnet
authors.affiliation: Department of Urology, Hopital Pitié-Salpétrière, Paris, France.
authors.forename: Thomas
authors.initials: T
authors.lastname: Seisen
authors.affiliation: Department of Statistics, CHU Rennes, Rennes, France.
authors.forename: Emmanuel
authors.initials: E
authors.lastname: Oger
authors.affiliation: Department of Urology, Hopital Pitié-Salpétrière, Paris, France.
authors.forename: Christophe
authors.initials: C
authors.lastname: Vaessen
authors.affiliation: Department of Urology, CHU Bordeaux, Bordeaux, France.
authors.forename: Yohann
authors.initials: Y
authors.lastname: Grassano
authors.affiliation: Department of Urology, CHU Toulouse, Toulouse, France.
authors.forename: Thibaut
authors.initials: T
authors.lastname: Benoit
authors.affiliation: Department of Urology, CHU Angers, Angers, France.
authors.forename: Julie
authors.initials: J
authors.lastname: Carrouget
authors.affiliation: Department of Urology, Hopital Pontchaillou, CHU Rennes, Rennes, France.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Pradère
authors.affiliation: Department of Urology, Hopital Pontchaillou, CHU Rennes, Rennes, France.
authors.forename: Zineddine
authors.initials: Z
authors.lastname: Khene
authors.affiliation: Department of Urology, CHU Rouen, Rouen, France.
authors.forename: Anthony
authors.initials: A
authors.lastname: Giwerc
authors.affiliation: Department of Urology, Hopital Pontchaillou, CHU Rennes, Rennes, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Mathieu
authors.affiliation: Department of Urology, CHU Toulouse, Toulouse, France.
authors.forename: Jean-Baptiste
authors.initials: JB
authors.lastname: Beauval
authors.affiliation: Department of Urology, CHU Rouen, Rouen, France.
authors.forename: François-Xavier
authors.initials: FX
authors.lastname: Nouhaud
authors.affiliation: Department of Urology, CHU Angers, Angers, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Bigot
authors.affiliation: Department of Urology, CHU Toulouse, Toulouse, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Doumerc
authors.affiliation: Department of Urology, CHU Bordeaux, Bordeaux, France.
authors.forename: Jean-Christophe
authors.initials: JC
authors.lastname: Bernhard
authors.affiliation: Department of Urology, Hopital Européen Georges-Pompidou, Paris, France.
authors.forename: Arnaud
authors.initials: A
authors.lastname: Mejean
authors.affiliation: Department of Urology, CHU Kremlin-Bicètre, Kremlin-Bicètre, France.
authors.forename: Jean-Jacques
authors.initials: JJ
authors.lastname: Patard
authors.affiliation: Department of Urology, University of Vienna, Vienna, Austria.
authors.forename: Sharokh
authors.initials: S
authors.lastname: Shariat
authors.affiliation: Department of Urology, Hopital Pitié-Salpétrière, Paris, France.
authors.forename: Morgan
authors.initials: M
authors.lastname: Roupret
authors.affiliation: Department of Urology, Hopital Pontchaillou, CHU Rennes, Rennes, France.
authors.forename: Karim
authors.initials: K
authors.lastname: Bensalah
mesh_terms: D000368:Aged; D016063:Blood Loss, Surgical; D018572:Disease-Free Survival; D005260:Female; D006801:Humans; D053208:Kaplan-Meier Estimate; D007680:Kidney Neoplasms / Q000473:pathology / Q000601:surgery*; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000009:adverse effects / Q000379:methods*; D011183:Postoperative Complications / Q000209:etiology*; D012189:Retrospective Studies; D065287:Robotic Surgical Procedures / Q000009:adverse effects; D015996:Survival Rate; D047368:Tumor Burden; D052096:Warm Ischemia