title: Late-onset sepsis due to Staphylococcus capitis 'neonatalis' in low-birthweight infants: a new entity?
abstract: During hospitalization, sepsis occurs in one of every five very-low-birthweight infants. The emergence of Staphylococcus capitis (SC)-related sepsis in preterm infants was observed recently. This study aimed to evaluate the clinical severity of SC-related sepsis in preterm infants. Of the 105 infants who presented with sepsis related to coagulase-negative staphylococci, 74 were SC. Severe morbidity was more common in the SC group (55.4%) than in the non-SC coagulase-negative staphylococci group (32.0%) (P=0.03). Multi-variate analysis identified SC-related sepsis as an independent risk factor for severe morbidity.
authors.affiliation: Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France; Faculty of Medicine of Tunis, University of Tunis El-Manar, Tunis, Tunisia.
authors.forename: M
authors.initials: M
authors.lastname: Ben Said
authors.affiliation: Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France; Rhone-Alpes Human Nutrition Research Centre, Pierre Bénite, France.
authors.forename: S
authors.initials: S
authors.lastname: Hays
authors.affiliation: Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France.
authors.forename: M
authors.initials: M
authors.lastname: Bonfils
authors.affiliation: Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France.
authors.forename: E
authors.initials: E
authors.lastname: Jourdes
authors.affiliation: Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, Ecole Normale Supérieure de Lyon, University of Lyon, Lyon, France; Department of Bacteriology - National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France.
authors.forename: J-P
authors.initials: JP
authors.lastname: Rasigade
authors.affiliation: Centre International de Recherche en Infectiologie, INSERM U1111, CNRS UMR5308, Ecole Normale Supérieure de Lyon, University of Lyon, Lyon, France; Department of Bacteriology - National Reference Centre for Staphylococci, Hospices Civils de Lyon, Lyon, France.
authors.forename: F
authors.initials: F
authors.lastname: Laurent
authors.affiliation: Neonatology, University Hospital Croix Rousse, Hospices Civils de Lyon, Lyon, France; Rhone-Alpes Human Nutrition Research Centre, Pierre Bénite, France; Lyon-Sud Charles Merieux Medical School, Claude Bernard University Lyon 1, Pierre Bénite, France. Electronic address: jean-charles.picaud@chu-lyon.fr.
authors.forename: J-C
authors.initials: JC
authors.lastname: Picaud
mesh_terms: D005260:Female; D006801:Humans; D007223:Infant; D007230:Infant, Low Birth Weight; D007231:Infant, Newborn; D000067562:Late Onset Disorders / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D008297:Male; D000071074:Neonatal Sepsis / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D011446:Prospective Studies; D013203:Staphylococcal Infections / Q000453:epidemiology* / Q000382:microbiology / Q000473:pathology; D013210:Staphylococcus / Q000145:classification / Q000302:isolation & purification*
keywords: Morbidity; Prematurity; Sepsis; Staphylococcus