title: Immune Gamma Globulin Therapeutic Indications in Immune Deficiency and Autoimmunity.
abstract: Immune gamma globulin (IgG) has a long history in the treatment of both primary immune deficiency and autoimmune disorders. Disease indications continue to expand and new-generation products increase the versatility of delivery. This review encompasses a historical perspective as well as current and future implications of human immune globulin for the treatment of immune-mediated illness.
authors.affiliation: Department of Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA.
authors.forename: Luanna
authors.initials: L
authors.lastname: Yang
authors.affiliation: Department of Pediatrics, Division of Rheumatology, Allergy, and Immunology, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA.
authors.forename: Eveline Y
authors.initials: EY
authors.lastname: Wu
authors.affiliation: Department of Medicine, Division of Rheumatology, Allergy, and Immunology and the Thurston Arthritis Research Center, University of North Carolina School of Medicine, Chapel Hill, NC, 27599, USA. teresa_tarrant@med.unc.edu.
authors.forename: Teresa K
authors.initials: TK
authors.lastname: Tarrant
mesh_terms: D015551:Autoimmunity / Q000276:immunology*; D006801:Humans; D007153:Immunologic Deficiency Syndromes / Q000188:drug therapy* / Q000276:immunology; D005719:gamma-Globulins / Q000627:therapeutic use*
chemical_list: D005719:gamma-Globulins
keywords: Autoimmunity; Common variable immunodeficiency; Guillain-Barré; Immune deficiency; Immune globulin; Kawasaki disease; Myositis; X-linked agammaglobulinemia