title: Potency Titration of Oral Polio Vaccine by Estimation of Live Virus Content Using Tissue Culture Technique.
abstract: Representative vaccines from 34 different batches of oral log10 (6.425) and a minimum titre of polio vaccine (OPV) were tested for potency by tissue culture technique. All 34 samples were found to be potent, a maximum titre of log10 (6.425) and a minimum titre of log10 (5.86) was obtained. In addition, 6 vaccines from the immunisation clinic (left over sample after immunisation) were also subjected to potency titration and their potency was found to be within normal limits. Adequate potency confirmed ideal storage condition of the vaccines in Armed Forces set up.
authors.affiliation: Ex-Post Graduate Student (Microbiology), Armed Forces Medical College, Pune - 411 040.
authors.forename: Shiva Priya
authors.initials: SP
authors.lastname: Eswaran
authors.affiliation: Senior Advisor (Pathology and Microbiology), 151 Base Hospital, C/o 99 APO.
authors.forename: A K
authors.initials: AK
authors.lastname: Praharaj
authors.affiliation: Classified Specialist (Pathology and Microbiology), 159 General Hospital, C/o 56 APO.
authors.forename: Y
authors.initials: Y
authors.lastname: Chander
authors.affiliation: Professor and Head, Department of Microbiology, Armed Forces Medical College, Pune - 411 040.
authors.forename: A
authors.initials: A
authors.lastname: Nagendra
keywords: Oral polio vaccine; Potency; Storage