title: [Chronic kidney disease associated with Poems syndrome: Report of one case].
abstract: POEMS syndrome is characterized by Polyneuropathy, Organomegaly, Endocrinopathy, Monoclonal protein and Skin changes. We report a woman with the syndrome, who had peripheral polyneuropathy, osteosclerotic myeloma, monoclonal IgA elevation, hypothyroidism, hypogonadotrophic hypogonadism, hyperprolactinemia, adrenal insufficiency, hepatosplenomegaly, lymphadenopathy, thyroid and parotid enlargement, Castlemans disease, papilledema, stiff and hyperpigmented skin, white nails, clubbing, ascites and chronic diarrhea. She had also a nephropathy characterized by microscopic hematuria, proteinuria, renal insufficiency and a unilateral kidney retraction. She was treated with melphalan and prednisone, achieving remission of the disease and nephropathy. She survived twelve years and died due to a myocardial infarction 20 years after POEMS diagnosis.
authors.forename: Jorge
authors.initials: J
authors.lastname: Vega
mesh_terms: D000328:Adult; D018450:Disease Progression; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D016878:POEMS Syndrome / Q000150:complications* / Q000473:pathology / Q000503:physiopathology; D051436:Renal Insufficiency, Chronic / Q000209:etiology* / Q000473:pathology / Q000503:physiopathology