title: Antibiotic Resistance: The Need For a Global Strategy.
abstract: The development of antibiotic resistance is a major problem for mankind and results in fatal consequences on a daily basis across the globe. There are a number of reasons for this situation including increasing globalization with worldwide travel, health tourism, over use and ineffective use (both in man and animals), and counterfeiting of the antimicrobial drug products we have available currently. Although there are huge economical, demographic, legal and logistic differences among the global communities, there are also differences regarding the best approach to dealing with antibiotic resistance. However, as resistant bacteria do not respect international borders, there is clearly a need for a global strategy to minimize the spread of antibiotic resistance, to optimize the use of antibiotics, and to facilitate the development of new and effective medications. This commentary provides an insight into the issues and some of the ongoing programs to ensure an effective treatment for the future.
authors.affiliation: GlaxoSmithKline, Hertfordshire, SG12 0DP UK. Electronic address: davidelder2110@gmail.com.
authors.forename: David P
authors.initials: DP
authors.lastname: Elder
authors.affiliation: Institute of Pharmaceutical Technology, University of Applied Sciences and Arts Northwestern Switzerland, CH-4132 Muttenz, Switzerland.
authors.forename: Martin
authors.initials: M
authors.lastname: Kuentz
authors.affiliation: Pharmaceutical Science and CMC Biologics, H. Lundbeck A/S, 2500 Valby, Denmark.
authors.forename: René
authors.initials: R
authors.lastname: Holm
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000600:supply & distribution / Q000627:therapeutic use*; D001424:Bacterial Infections / Q000188:drug therapy* / Q000382:microbiology; D055808:Drug Discovery / Q000191:economics / Q000379:methods*; D024881:Drug Resistance, Bacterial / Q000187:drug effects*; D017723:Drug Utilization Review / Q000706:statistics & numerical data; D006801:Humans; D007391:International Cooperation; D055553:Prescription Drugs / Q000600:supply & distribution
chemical_list: D000900:Anti-Bacterial Agents; D055553:Prescription Drugs
keywords: antiinfectives; drug resistance; drug-like properties; formulation; global health