title: Signaling proteins in the spotlight.
abstract: The molecular side of signaling still has many secrets to reveal. This Editorial Guide describes areas of particular interest with regard to understanding cellular regulation at the level of individual molecules and macromolecular complexes. Advances in technology and the accumulation of proteomic and genomic data reveal previously unknown components of signaling networks, the spatial organization of macromolecular complexes, and how information flows through the networks to produce specific cellular responses.
authors.affiliation: Editor, Science Signaling, AAAS, Washington, DC 20005, USA. ngough@aaas.org.
authors.forename: Nancy R
authors.initials: NR
authors.lastname: Gough
mesh_terms: D000818:Animals; D053263:Gene Regulatory Networks / Q000502:physiology*; D006801:Humans; D020543:Proteome / Q000235:genetics / Q000378:metabolism*; D040901:Proteomics; D015398:Signal Transduction / Q000502:physiology*
chemical_list: D020543:Proteome