title: Role and analysis of monocyte subsets in cardiovascular disease. Joint consensus document of the European Society of Cardiology (ESC) Working Groups "Atherosclerosis & Vascular Biology" and "Thrombosis".
abstract: Monocytes as cells of the innate immunity are prominently involved in the development of atherosclerotic lesions. The heterogeneity of blood monocytes has widely been acknowledged by accumulating experimental and clinical data suggesting a differential, subset-specific contribution of the corresponding subpopulations to the pathology of cardiovascular and other diseases. This document re-evaluates current nomenclature and summarises key findings on monocyte subset biology to propose a consensus statement about phenotype, separation and quantification of the individual subsets.
authors.affiliation: Dr. Christian Weber, LMU Munich - Cardiovascular Prevention, Pettenkoferstr. 9, 80336 Munich, Germany, Tel.: +49 89 4400 54350, Fax: +49 89 4400 54352, E-mail: chweber@med.lmu.de.
authors.forename: Christian
authors.initials: C
authors.lastname: Weber
authors.forename: Eduard
authors.initials: E
authors.lastname: Shantsila
authors.affiliation: Dr. Michael Hristov, LMU Munich - Cardiovascular Prevention, Pettenkoferstr. 9, 80336 Munich, Germany, Tel.: +49 89 4400 54350, Fax: +49 89 4400 54352, E-mail: mhristov@med.lmu.de.
authors.forename: Michael
authors.initials: M
authors.lastname: Hristov
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Caligiuri
authors.forename: Tomasz
authors.initials: T
authors.lastname: Guzik
authors.forename: Gunnar H
authors.initials: GH
authors.lastname: Heine
authors.forename: Imo E
authors.initials: IE
authors.lastname: Hoefer
authors.forename: Claudia
authors.initials: C
authors.lastname: Monaco
authors.forename: Karlheinz
authors.initials: K
authors.lastname: Peter
authors.forename: Ed
authors.initials: E
authors.lastname: Rainger
authors.forename: Agneta
authors.initials: A
authors.lastname: Siegbahn
authors.forename: Sabine
authors.initials: S
authors.lastname: Steffens
authors.forename: Johann
authors.initials: J
authors.lastname: Wojta
authors.forename: Gregory Y H
authors.initials: GY
authors.lastname: Lip
mesh_terms: D050197:Atherosclerosis / Q000503:physiopathology*; D002318:Cardiovascular Diseases / Q000503:physiopathology*; D032921:Consensus; D006801:Humans; D009000:Monocytes / Q000166:cytology*; D013927:Thrombosis
keywords: Atherosclerosis; leukocyte function / activation; monocytes