title: The Neuro Bureau ADHD-200 Preprocessed repository.
abstract: In 2011, the "ADHD-200 Global Competition" was held with the aim of identifying biomarkers of attention-deficit/hyperactivity disorder from resting-state functional magnetic resonance imaging (rs-fMRI) and structural MRI (s-MRI) data collected on 973 individuals. Statisticians and computer scientists were potentially the most qualified for the machine learning aspect of the competition, but generally lacked the specialized skills to implement the necessary steps of data preparation for rs-fMRI. Realizing this barrier to entry, the Neuro Bureau prospectively collaborated with all competitors by preprocessing the data and sharing these results at the Neuroimaging Informatics Tools and Resources Clearinghouse (NITRC) (http://www.nitrc.org/frs/?group_id=383). This "ADHD-200 Preprocessed" release included multiple analytical pipelines to cater to different philosophies of data analysis. The processed derivatives included denoised and registered 4D fMRI volumes, regional time series extracted from brain parcellations, maps of 10 intrinsic connectivity networks, fractional amplitude of low frequency fluctuation, and regional homogeneity, along with grey matter density maps. The data was used by several teams who competed in the ADHD-200 Global Competition, including the winning entry by a group of biostaticians. To the best of our knowledge, the ADHD-200 Preprocessed release was the first large public resource of preprocessed resting-state fMRI and structural MRI data, and remains to this day the only resource featuring a battery of alternative processing paths.
authors.affiliation: The Neuro Bureau, Germany; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Canada; Département d'Informatique et de Recherche Opérationnelle, Université de Montréal, Montréal, Canada. Electronic address: pierre.bellec@criugm.qc.ca.
authors.forename: Pierre
authors.initials: P
authors.lastname: Bellec
authors.affiliation: The Neuro Bureau, Germany; Google DeepMind, London, UK. Electronic address: carltonchu1@gmail.com.
authors.forename: Carlton
authors.initials: C
authors.lastname: Chu
authors.affiliation: The Neuro Bureau, Germany; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Canada; Integrated Program in Neuroscience, McGill University, Montreal, Canada. Electronic address: francois.chouinard@gmail.com.
authors.forename: François
authors.initials: F
authors.lastname: Chouinard-Decorte
authors.affiliation: The Neuro Bureau, Germany; Centre de Recherche de l'Institut Universitaire de Gériatrie de Montréal, Montréal, Canada; Département d'Anthropologie, Université de Montréal, Montréal, Canada. Electronic address: yanamarji@gmail.com.
authors.forename: Yassine
authors.initials: Y
authors.lastname: Benhajali
authors.affiliation: The Neuro Bureau, Germany; Max Planck Research Group for Neuroanatomy & Connectivity, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. Electronic address: margulies@cbs.mpg.de.
authors.forename: Daniel S
authors.initials: DS
authors.lastname: Margulies
authors.affiliation: The Neuro Bureau, Germany; Computational Neuroimaging Laboratory, Center for Biomedical Imaging and Neuromodulation, Nathan S. Kline Institute for Psychiatric Research, Orangeburg, NY, USA; Center for the Developing Brain, Child Mind Institute, New York, NY, USA. Electronic address: ccraddock@nki.rfmh.org.
authors.forename: R Cameron
authors.initials: RC
authors.lastname: Craddock
mesh_terms: D000293:Adolescent; D000328:Adult; D001289:Attention Deficit Disorder with Hyperactivity / Q000000981:diagnostic imaging* / Q000503:physiopathology*; D002648:Child; D016208:Databases, Factual; D005260:Female; D059907:Functional Neuroimaging; D006801:Humans; D033181:Information Dissemination; D008279:Magnetic Resonance Imaging; D008297:Male; D055815:Young Adult
keywords: Data sharing; Neuroimaging competition; Preprocessed fMRI