title: Body Composition and Bone Mineral Density in Patients With Heart Failure.
abstract: The purpose of this study was to examine associations among bone mineral density, osteopenia/osteoporosis, body mass index (BMI), and body composition in patients with heart failure (HF). A total of 119 patients (age = 61 ± 12 years, 65% male) underwent dual-energy X-ray absorptiometry scans to determine bone mineral density and body composition. In multivariable linear regressions, BMI, relative skeletal muscle index (RSMI), and mineral-free lean mass were positively associated with total body bone mineral density. Mineral-free lean mass was most strongly associated with bone mineral density (β = .398). In multivariable logistic regressions, higher BMI, RSMI, and mineral-free lean mass were associated with lower odds for osteopenia/osteoporosis. Fat mass was not associated with total body bone mineral density or osteopenia/osteoporosis. These results suggest that muscle mass may be the important component of body mass associated with bone mineral density in patients with HF.
authors.affiliation: 1 Washington State University College of Nursing, Spokane, WA, USA.
authors.forename: Demetrius A
authors.initials: DA
authors.lastname: Abshire
authors.affiliation: 2 University of Kentucky College of Nursing, Lexington, KY, USA.
authors.forename: Debra K
authors.initials: DK
authors.lastname: Moser
authors.affiliation: 3 University of Kentucky Department of Kinesiology and Health Promotion, Lexington, KY, USA.
authors.forename: Jody L
authors.initials: JL
authors.lastname: Clasey
authors.affiliation: 2 University of Kentucky College of Nursing, Lexington, KY, USA.
authors.forename: Misook L
authors.initials: ML
authors.lastname: Chung
authors.affiliation: 4 Indiana University School of Nursing, Indianapolis, IN, USA.
authors.forename: Susan J
authors.initials: SJ
authors.lastname: Pressler
authors.affiliation: 5 Emory University Nell Hodgson Woodruff School of Nursing, Atlanta, GA, USA.
authors.forename: Sandra B
authors.initials: SB
authors.lastname: Dunbar
authors.affiliation: 6 University of Arkansas for Medical Sciences College of Nursing, Little Rock, AR, USA.
authors.forename: Seongkum
authors.initials: S
authors.lastname: Heo
authors.affiliation: 2 University of Kentucky College of Nursing, Lexington, KY, USA.
authors.forename: Terry A
authors.initials: TA
authors.lastname: Lennie
mesh_terms: D001823:Body Composition / Q000502:physiology*; D015992:Body Mass Index; D015519:Bone Density / Q000502:physiology*; D005260:Female; D006333:Heart Failure / Q000150:complications*; D006801:Humans; D008297:Male; D008875:Middle Aged; D018482:Muscle, Skeletal / Q000502:physiology; D010024:Osteoporosis / Q000150:complications*
keywords: bone mineral density; heart failure; obesity; sarcopenia