title: Primary unclassified sarcoma of the parotid gland: a case of diagnostic and therapeutic challenge.
abstract: Malignant salivary gland sarcomas represent a clinically and histologically diagnostic challenge. Primary unclassified sarcomas of the parotid gland consist a rare salivary gland tumor. We report an unusual case of such a tumor, which occurred in the right parotid gland of a 54-year-old male and presented as an asymptomatic painless mass. The pathologoanatomical examination revealed a rhabdoid large-cell unclassified sarcoma. The patient was treated with superficial parotidectomy and adjuvant radiotherapy. No recurrence was noted in a 10-year follow-up period. Due to the rare occurrence of primary unclassified sarcomas, there is no evidence-based treatment of choice. An optimal approach is best planned in a multidisciplinary setting, taking into consideration the resectability of the tumor, individual patient characteristics, presence of local or distant metastatic activity, local infiltrative behavior and tumor stage. A close follow-up of the patient is strongly recommended.
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Siloah St. Trudpert Hospital, Wilferdinger Strasse 67, 75179, Pforzheim, Germany. psaravakos@yahoo.com.
authors.forename: Panagiotis
authors.identifier: http://orcid.org/0000-0002-7891-8247
authors.initials: P
authors.lastname: Saravakos
authors.affiliation: Department of Otorhinolaryngology, Head and Neck Surgery, Siloah St. Trudpert Hospital, Wilferdinger Strasse 67, 75179, Pforzheim, Germany.
authors.forename: Joerg
authors.initials: J
authors.lastname: Hartwein
authors.affiliation: Institute of Pathology and Molecular Pathology, Pforzheim Hospital, Kanzlerstrasse 2-6, 75175, Pforzheim, Germany.
authors.forename: Afshin
authors.initials: A
authors.lastname: Fayyazi
mesh_terms: D058070:Asymptomatic Diseases; D003937:Diagnosis, Differential; D006801:Humans; D008297:Male; D008875:Middle Aged; D037981:Neck Dissection / Q000379:methods*; D010306:Parotid Gland / Q000000981:diagnostic imaging / Q000473:pathology; D010307:Parotid Neoplasms / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D018714:Radiotherapy, Adjuvant / Q000379:methods*; D012509:Sarcoma / Q000175:diagnosis / Q000473:pathology / Q000532:radiotherapy / Q000601:surgery; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
keywords: Head and neck sarcomas; NOS sarcoma; Parotid tumor; Primary unclassified sarcoma; Salivary malignancy