title: Microbially Produced Acetate: A "Missing Link" in Understanding Obesity?
abstract: Numerous studies have connected the gut microbiome with diet-induced obesity; however, mechanistic explanations for the host-microbial interactions are needed. Perry et al. (2016) present studies suggesting that microbially produced acetate (MPA) increases post-prandial insulin release via a sequential and integrated gut, brain, and pancreatic signaling network promoting energy retention.
authors.affiliation: Departments of Medicine and Microbiology, New York University Langone Medical Center, New York, NY 10016, USA.
authors.forename: Chad M
authors.initials: CM
authors.lastname: Trent
authors.affiliation: Departments of Medicine and Microbiology, New York University Langone Medical Center, New York, NY 10016, USA; Department of Veterans Affairs Medical Center, New York, NY 10010, USA. Electronic address: martin.blaser@nyumc.org.
authors.forename: Martin J
authors.initials: MJ
authors.lastname: Blaser
mesh_terms: D000085:Acetates; D004032:Diet; D004734:Energy Metabolism; D041981:Gastrointestinal Tract; D006801:Humans; D009765:Obesity
chemical_list: D000085:Acetates