title: [Latest international guidelines for screening, prevention and treatment of familial breast cancer - implications for the relevant practice in Hungary].
abstract: BACKGROUND
  Screening, prevention and treatment of familial breast cancer require a multidisciplinary approach. New guidelines were published in the United Kingdom for the management of familial breast cancer.
  
  
  OBJECTIVE
  The authors summarise these new guidelines and analyse the relevant practice in Hungary.
  
  
  METHODS
  Relevant guidelines of the National Institute for Health and Care Excellence and Familial Breast Cancer Report (NHS Scotland) are described.
  
  
  RESULTS
  New guidelines will increase the number of genetic tests as well as genetic counselling. An increase in the number of breast magnetic resonance imaging is expected, too. Chemoprevention can be offered for individuals with medium risk and above. Promising trials are underway with platinum based chemotherapy and polyADP-ribose polimerase inhibitors for the systemic treatment of familial breast cancer. The increase in the number of genetic tests, counselling, and breast magnetic resonance imaging may have a significant impact on health care budget.
  
  
  CONCLUSIONS
  These guidelines will change some aspects of the current management of familial breast cancer. Orv. Hetil., 2016, 157(28), 1117-1125.
authors.affiliation: Department of Surgery, New Victoria Hospital és Queen Elizabeth University Hospital Grange Road, Glasgow G42 9LF, UK.
authors.forename: László
authors.initials: L
authors.lastname: Romics
authors.affiliation: Onkológiai Intézet, Debreceni Egyetem, Általános Orvostudományi Kar, Klinikai Központ Debrecen.
authors.forename: Judit
authors.initials: J
authors.lastname: Kocsis
authors.affiliation: Radiológiai Klinika, Diagnoscan Magyarország Kft., Szegedi Tudományegyetem, Általános Orvostudományi Kar Szeged.
authors.forename: Katalin
authors.initials: K
authors.lastname: Ormándi
authors.affiliation: I. Sebészeti Klinika, Semmelweis Egyetem, Általános Orvostudományi Kar Budapest.
authors.forename: Béla Ákos
authors.initials: BÁ
authors.lastname: Molnár
mesh_terms: D000971:Antineoplastic Combined Chemotherapy Protocols / Q000191:economics / Q000627:therapeutic use*; D019313:BRCA1 Protein / Q000235:genetics; D024682:BRCA2 Protein / Q000235:genetics; D001943:Breast Neoplasms / Q000175:diagnosis / Q000235:genetics* / Q000517:prevention & control / Q000628:therapy*; D018890:Chemoprevention / Q000191:economics / Q000379:methods / Q000639:trends; D004739:England; D005260:Female; D020022:Genetic Predisposition to Disease; D005820:Genetic Testing / Q000191:economics / Q000592:standards / Q000639:trends; D006801:Humans; D006814:Hungary; D038622:Internationality; D008327:Mammography; D009154:Mutation; D010052:Ovariectomy; D017410:Practice Guidelines as Topic; D000072036:Prophylactic Mastectomy / Q000191:economics; D018570:Risk Assessment; D012307:Risk Factors; D058994:Salpingectomy; D014852:Wales
chemical_list: D019313:BRCA1 Protein; C492913:BRCA1 protein, human; D024682:BRCA2 Protein; C551750:BRCA2 protein, human
keywords: ajánlás; breast cancer; emlőrák; familial; guideline; kezelés; management; szűrés; örökletes