title: Arsenic exposure and risk of preeclampsia in a Mexican mestizo population.
abstract: Exposure to arsenic in drinking water has been associated with various complications of pregnancy including fetal loss, low birth weight, anemia, gestational diabetes and spontaneous abortion. However, to date, there are no studies evaluating its possible association with preeclampsia.
  
  
  
  This case-control study involved 104 preeclamptic and 202 healthy pregnant women. The concentrations of arsenic in drinking water and urine were measured using a Microwave Plasma-Atomic Emission Spectrometer.
  
  
  
  We found relatively low levels of arsenic in household tap water (range of 2.48-76.02 μg/L) and in the urine of the participants (7.1 μg/L vs 6.78 μg/L in cases and controls, respectively).
  
  
  
  The analysis between groups showed for the first time that at these lower levels of exposure there is no association with preeclampsia.
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
authors.forename: Ada
authors.initials: A
authors.lastname: Sandoval-Carrillo
authors.affiliation: Faculty of Medicine and Nutrition, Juarez University of the State of Durango, Zip Code 34000, Durango, Mexico.
authors.forename: Edna M
authors.initials: EM
authors.lastname: Méndez-Hernández
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
authors.forename: Elizabeth I
authors.initials: EI
authors.lastname: Antuna-Salcido
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
authors.forename: Sergio M
authors.initials: SM
authors.lastname: Salas-Pacheco
authors.affiliation: General Hospital 450, Health Services, Durango, Zip Code 34000, Mexico.
authors.forename: Fernando
authors.initials: F
authors.lastname: Vázquez-Alaniz
authors.affiliation: Faculty of Medicine and Nutrition, Juarez University of the State of Durango, Zip Code 34000, Durango, Mexico.
authors.forename: Alfredo
authors.initials: A
authors.lastname: Téllez-Valencia
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
authors.forename: Marisela
authors.initials: M
authors.lastname: Aguilar-Durán
authors.affiliation: Faculty of Chemical Sciences, Juarez University of the State of Durango, Zip Code 34000, Durango, Mexico.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Barraza-Salas
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
authors.forename: Francisco X
authors.initials: FX
authors.lastname: Castellanos-Juárez
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico.
authors.forename: Osmel
authors.initials: O
authors.lastname: La Llave-León
authors.affiliation: Institute of Scientific Research, Juarez University of the State of Durango, Av. Universidad y Fanny Anitua s/n. Col. Centro, C.P. 34000, Durango, Dgo, Mexico. jsalas_pacheco@hotmail.com.
authors.forename: José M
authors.initials: JM
authors.lastname: Salas-Pacheco
mesh_terms: D000293:Adolescent; D000328:Adult; D001151:Arsenic / Q000032:analysis* / Q000652:urine; D016022:Case-Control Studies; D060766:Drinking Water / Q000737:chemistry*; D005006:Ethnicity; D005260:Female; D006801:Humans; D008800:Mexico / Q000453:epidemiology; D011225:Pre-Eclampsia / Q000453:epidemiology*; D011247:Pregnancy; D011446:Prospective Studies; D055815:Young Adult
chemical_list: D060766:Drinking Water; D001151:Arsenic
keywords: Arsenic; Drinking water; Preeclampsia