title: Status epilepticus caused by cerebral amyloid angiopathy-related inflammation.
abstract: This report discusses a case of nonconvulsive status epilepticus, caused by cerebral amyloid angiopathy-related inflammation. Brain biopsy demonstrated cerebral amyloid angiopathy, with clinical and radiographic features indicative of a fluctuating inflammatory process. Immunomodulatory treatment with pulse steroids resulted in rapid and dramatic clinical and radiographic improvement. Cerebral amyloid angiopathy-related inflammation should be considered in the differential diagnosis of new-onset seizures after the age of 40, when associated with fluctuating multifocal T2 hyperintensities and petechial hemorrhages on gradient echo (GRE) or susceptibility-weighted (SWI) MRI sequences.
authors.affiliation: Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Tolchin
authors.affiliation: Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States.
authors.forename: Tadeau
authors.initials: T
authors.lastname: Fantaneanu
authors.affiliation: Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States.
authors.forename: Michael
authors.initials: M
authors.lastname: Miller
authors.affiliation: Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States.
authors.forename: Jeffrey
authors.initials: J
authors.lastname: Helgager
authors.affiliation: Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States.
authors.forename: Jong Woo
authors.initials: JW
authors.lastname: Lee
keywords: Cerebral amyloid angiopathy; EEG; Inflammation; MRI; Pathology; Status epilepticus