title: Dataset on inflammatory proteins expressions and sialic acid levels in apolipoprotein E-deficient mice with administration of N-acetylneuraminic acid and/or quercetin.
abstract: The data presented in this article describe an effect of N-acetylneuraminic acid and/or quercetin on the inflammatory proteins expressions (TNF-α, ICAM-1, VCAM-1 and MOMA-2) and the N-acetylneuraminic acid (NANA) levels of apolipoprotein E-deficient mice that are given a high-fat diet. Protein expression was performed by immunohistochemical imaging and NANA was quantified by liquid chromatography-tandem mass spectrometry (LC-MS/MS) or semi-quantified using Image-Pro Plus software after ligation with fluorescein-5-thiosemicarbazide (FTSC). Further interpretation and discussion could be found at our research article entitled "Exogenous supplement of N-acetylneuraminic acid ameliorates atherosclerosis in apolipoprotein E-deficient mice" (Guo et al., 2016) [1].
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Rongrong
authors.initials: R
authors.lastname: Dong
authors.affiliation: Department of Chemistry and Chemical Engineering, Weifang University, Weifang 261061, China.
authors.forename: Fahui
authors.initials: F
authors.lastname: Li
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Shucun
authors.initials: S
authors.lastname: Qin
authors.affiliation: Department of Ophthalmology, Affilated Hospital of Taishan Medical University, Taian 271000, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Yanhong
authors.initials: Y
authors.lastname: Si
authors.affiliation: School of Medicine and Pharmacy, Ocean University of China, Qingdao 266003, China.
authors.forename: Xuelian
authors.initials: X
authors.lastname: Xu
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Tian
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Lei
authors.initials: L
authors.lastname: Zhai
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Guangjie
authors.initials: G
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Yongjun
authors.initials: Y
authors.lastname: Li
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Yawei
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Ying
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Atherosclerosis in Universities of Shandong Province, Institute of Atherosclerosis, Taishan Medical University, Taian 271000, China.
authors.forename: Shoudong
authors.initials: S
authors.lastname: Guo
keywords: Fluorescent labeling; Imaging; Immunohistochemistry; LC-MS/MS; Sialic acid