title: Brønsted Acid Catalyzed Homoconjugate Addition of Organotrifluoroborates to Arylated Cyclopropyl Ketones.
abstract: A novel and practical homoconjugate addition of alkenyl, alkynyl, heteroaryl, and aryl trifluoroborates to arylated cyclopropyl ketones to synthesize γ,γ-disubstituted ketones is reported. A preliminary mechanistic proposal involving ketone protonation, an intermediary carbocation, and intermolecular nucleophile addition has been made based on control studies.
authors.affiliation: Department of Chemistry, University of Houston , 3585 Cullen Boulevard, Fleming Building Room 112, Houston, Texas 77204-5003, United States.
authors.forename: Truong N
authors.initials: TN
authors.lastname: Nguyen
authors.affiliation: Department of Chemistry, University of Houston , 3585 Cullen Boulevard, Fleming Building Room 112, Houston, Texas 77204-5003, United States.
authors.forename: Thien S
authors.initials: TS
authors.lastname: Nguyen
authors.affiliation: Department of Chemistry, University of Houston , 3585 Cullen Boulevard, Fleming Building Room 112, Houston, Texas 77204-5003, United States.
authors.forename: Jeremy A
authors.initials: JA
authors.lastname: May