title: Infrared spectroscopic analysis of staghorn calculi obtained after open renal surgery in a urology unit of Sri Lanka.
abstract: The composition of renal stones varies widely among populations. The aim of our study was to determine the composition of staghorn renal stones using Fourier transform infrared (FTIR) spectroscopy in a cohort of Sri Lankan patients. Forty two staghorn calculi removed from kidneys of adult patients during open surgery were analysed. There were 32 men. Nineteen (45%) were calcium oxalate monohydrate (whewellite) stones. Stones containing a mixture of calcium oxalate and calcium hydroxyl phosphate (apatite) were found in 16 (38%). Only 4 (10%) staghorn calculi were coposed of struvite. Three (7%) were uric acid stones. So most staghorn renal stones in Sri Lanka are calcium oxalate. Contrary to the traditional view based on studies done in the western world, only 10% of staghorn calculi removed from patients in Sri Lanka are struvite or infection stones. This could be the reason for kidneys with staghorn calculi in Sri Lanka to retain their function.
authors.forename: K S
authors.initials: KS
authors.lastname: Wijayarathna
authors.forename: G G
authors.initials: GG
authors.lastname: Weerasingha
authors.forename: A S
authors.initials: AS
authors.lastname: Weligamage
authors.forename: R
authors.initials: R
authors.lastname: Chandrajith
authors.affiliation: Urology Unit, Colombo South Teaching Hospital, Sri Lanka. amabey@sltnet.lk.
authors.forename: A M
authors.initials: AM
authors.lastname: Abeygunasekera
mesh_terms: D000328:Adult; D000368:Aged; D002129:Calcium Oxalate / Q000032:analysis; D005260:Female; D006801:Humans; D006882:Hydroxyapatites / Q000032:analysis; D008297:Male; D008875:Middle Aged; D017550:Spectroscopy, Fourier Transform Infrared / Q000379:methods*; D013188:Sri Lanka; D000069856:Staghorn Calculi / Q000737:chemistry* / Q000601:surgery; D000069877:Struvite / Q000032:analysis; D014527:Uric Acid / Q000032:analysis
chemical_list: D006882:Hydroxyapatites; D002129:Calcium Oxalate; D014527:Uric Acid; D000069877:Struvite