title: [Mode of delivery among HIV-positive pregnant women in areas with high prevalence of HIV in China, 2007-2013].
abstract: OBJECTIVE
  To describe the changing demographic profile over time of pregnant women diagnosed with HIV infection, and trends in mode of delivery and pregnancy outcome.
  
  
  METHODS
  An observational investigation was conducted based on a population of 1 128 HIV-positive pregnant women at eight sites in China in provinces with high prevalence of HIV among pregnant women and children between 2007 and 2013. The study area included Shangcai and Weishi counties in Henan province; Ruili and Longchuan counties and Linxiang prefecture in Yunnan province; Yining County in Xinjiang; and Lingshan county and Babu district in Guangxi province. Main outcome measures were maternal characteristics, mode of delivery, and related trends over time by Cochram-Mantel-Haenszel(CMH) χ(2)-test.
  
  
  RESULTS
  A total hospital delivery rate of 96.4% was reported. For each year during the period 2007-2013, hospital delivery rates were 95.1% (253/266), 94.8% (188/198), 93.7% (164/175), 98.8% (159/161), 98.6% (141/143), 97.4% (114/117), and 100.0% (68/68), respectively (χ(2)CMH=7.68, P=0.006). The neonatal survival rate increased by 0.7% incrementally from 2007 to 2013, with 98.5% (262/266), 99.0% (196/198), 99.4% (174/175), 99.4% (160/161), 100.0% (143/143), 100.0% (117/117), and 100.0% (68/68), respectively (χ(2)CMH=4.58, P=0.030). The proportions of vaginal deliveries in those years were 62.2% (166/266), 54.8% (109/198), 59.9% (105/175), 61.7% (100/161), 66.7% (96/143), 58.8% (69/117), and 66.7% (46/68), respectively (χ(2)CMH=1.19, P= 0.276). The average rate for midwives skilled in procedures such as artificial rupture of membranes and episiotomy was 37.8% (261/691), with proportions decreasing during the study period at 39.2% (65/166), 47.4% (52/109), 35.9% (38/105), 46.0% (46/100), 25.5% (25/96), 31.2% (22/69), and 28.3% (13/46), respectively (χ(2CMH)=6.76, P=0.009).
  
  
  CONCLUSIONS
  The annual rate of reported hospital delivery increased between 2007 and 2013, with a declining rate of skilled midwifery over the same period. Survival of neonates born to HIV-infected mothers in China has increased to nearly equivalent levels as those of developed countries.
authors.affiliation: National Center for Women and Children's Health, Chinese Center for Disease Control and Prevention, Beijing 100010, China.
authors.forename: Q
authors.initials: Q
authors.lastname: Wang
authors.forename: L H
authors.initials: LH
authors.lastname: Wang
authors.forename: A L
authors.initials: AL
authors.lastname: Wang
authors.forename: F
authors.initials: F
authors.lastname: Wang
authors.forename: X Y
authors.initials: XY
authors.lastname: Wang
authors.forename: Y P
authors.initials: YP
authors.lastname: Qiao
authors.forename: M
authors.initials: M
authors.lastname: Su
authors.forename: L X
authors.initials: LX
authors.lastname: Dou
authors.forename: L W
authors.initials: LW
authors.lastname: Fang
mesh_terms: D044966:Anti-Retroviral Agents / Q000627:therapeutic use*; D002648:Child; D002681:China / Q000453:epidemiology; D036861:Delivery, Obstetric / Q000379:methods* / Q000706:statistics & numerical data; D005260:Female; D015658:HIV Infections / Q000150:complications / Q000175:diagnosis / Q000188:drug therapy / Q000453:epidemiology*; D006801:Humans; D018445:Infectious Disease Transmission, Vertical; D011247:Pregnancy; D011251:Pregnancy Complications, Infectious / Q000175:diagnosis / Q000453:epidemiology; D011256:Pregnancy Outcome / Q000453:epidemiology*; D015995:Prevalence
chemical_list: D044966:Anti-Retroviral Agents