title: Abscopal effect in metastatic renal cell carcinoma.
abstract: We report a case about a possible abscopal effect in a patient with metastatic renal cell carcinoma. Palliative conventional radiation of a metastatic lesion in the neck was performed and in the months after this treatment had been applied, clearance of the non-irradiated lung metastases and a subcutaneous nodule was observed. The abscopal effect is a phenomenon in which local radiotherapy is associated with regression of metastatic cancer at a distance from the irradiated site. It's a rare phenomenon; until now, only case reports and small series demonstrate the abscopal effect. This case supports the fact that further studying of this rare event must be encouraged.
authors.affiliation: a Department of Medical Oncology , Gent University Hospital , De Pintelaan 185, 2B-II, 9000 Gent , Belgium.
authors.forename: Mieke
authors.initials: M
authors.lastname: Van de Walle
authors.affiliation: b Department of Medical Oncology , AZ Delta , Wilgenstraat 2, 8800 Roeselare , Belgium.
authors.forename: Jan
authors.initials: J
authors.lastname: Demol
authors.affiliation: c Department of Radiation Oncology , AZ Delta , Wilgenstraat 2, 8800 Roeselare , Belgium.
authors.forename: Lorenzo
authors.initials: L
authors.lastname: Staelens
authors.affiliation: a Department of Medical Oncology , Gent University Hospital , De Pintelaan 185, 2B-II, 9000 Gent , Belgium.
authors.forename: Sylvie
authors.initials: S
authors.lastname: Rottey
mesh_terms: D000368:Aged; D002292:Carcinoma, Renal Cell / Q000532:radiotherapy* / Q000556:secondary*; D005260:Female; D006258:Head and Neck Neoplasms / Q000532:radiotherapy* / Q000556:secondary; D006801:Humans; D007680:Kidney Neoplasms / Q000473:pathology*; D008175:Lung Neoplasms / Q000532:radiotherapy* / Q000556:secondary; D012878:Skin Neoplasms / Q000532:radiotherapy* / Q000556:secondary
keywords: Abscopal effect; Carcinoma; Case report; Palliative conventional radiation; Renal cell