title: [Relationship between Obesity, Adipokines and Systemic Lupus Erythematosus].
abstract: Obesity is a pro-inflammatory state characterized by phenotypic changes in macrophages, alterationson cytokines balance, and increasing expression of regulatory molecules of the immune system derived from adipocytes and adipose tissue macrophages - also known as adipokines. Currently, leptin, adiponectin and resistin are, among others, one of the most known adipokines. Theseadipokinesmight play a possible role in systemic lupus erythematosus pathogenesis, by promotingdifferent pro-inflammatory conditions. Adipokines represent a possible treatment target in patients with lupus.
authors.affiliation: Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
authors.forename: Tomas
authors.initials: T
authors.lastname: Urrego
authors.affiliation: Grupo de Inmunología Celular e Inmunogenética, Universidad de Antioquia, Medellín, Colombia.
authors.forename: Gloria M
authors.initials: GM
authors.lastname: Vásquez
authors.affiliation: Grupo de Inmunología Celular e Inmunogenética, Universidad de Antioquia, Medellín, Colombia.
authors.forename: Jose A
authors.initials: JA
authors.lastname: Gómez-Puerta
mesh_terms: D054392:Adipokines / Q000097:blood / Q000502:physiology*; D015415:Biomarkers / Q000097:blood; D006801:Humans; D008180:Lupus Erythematosus, Systemic / Q000097:blood / Q000503:physiopathology*; D009765:Obesity / Q000097:blood / Q000503:physiopathology*
chemical_list: D054392:Adipokines; D015415:Biomarkers