title: Hantavirus cardiopulmonary syndrome successfully treated with high-volume hemofiltration.
abstract: Hantavirus cardiopulmonary syndrome has a high mortality rate, and early connection to extracorporeal membrane oxygenation has been suggested to improve outcomes. We report the case of a patient with demonstrated Hantavirus cardiopulmonary syndrome and refractory shock who fulfilled the criteria for extracorporeal membrane oxygenation and responded successfully to high volume continuous hemofiltration. The implementation of high volume continuous hemofiltration along with protective ventilation reversed the shock within a few hours and may have prompted recovery. In patients with Hantavirus cardiopulmonary syndrome, a short course of high volume continuous hemofiltration may help differentiate patients who can be treated with conventional intensive care unit management from those who will require more complex therapies, such as extracorporeal membrane oxygenation.
authors.affiliation: Departamento de Medicina Intensiva, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Bugedo
authors.affiliation: Departamento de Medicina Intensiva, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.
authors.forename: Jorge
authors.initials: J
authors.lastname: Florez
authors.affiliation: Departamento de Enfermedades Infecciosas e Imunologia Pediátrica, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.
authors.forename: Marcela
authors.initials: M
authors.lastname: Ferres
authors.affiliation: Departamento de Nefrologia, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.
authors.forename: Eric
authors.initials: E
authors.lastname: Roessler
authors.affiliation: Departamento de Medicina Intensiva, Escuela de Medicina, Pontificia Universidad Catolica de Chile, Santiago, Chile.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Bruhn
mesh_terms: D000328:Adult; D005260:Female; D018804:Hantavirus Pulmonary Syndrome / Q000503:physiopathology / Q000628:therapy*; D006440:Hemofiltration / Q000379:methods*; D006801:Humans; D012121:Respiration, Artificial / Q000379:methods*; D016896:Treatment Outcome