title: Visualization of Changes in the Choriocapillaris, Choroidal Vessels, and Retinal Morphology After Focal Laser Photocoagulation Using OCT Angiography.
abstract: To utilize optical coherence tomography (OCT) and OCT angiography (OCTA) to describe alterations in the retinal and choriocapillaris vasculature following remote laser photocoagulation. Lesions are classified on the basis of choriocapillaris alteration as evaluated on en face OCTA.
  
  
  
  This was a retrospective, cross-sectional study analyzing 28 laser photocoagulation scars from 8 patients treated for diabetic macular edema. All eyes were analyzed using a combination of OCTA, en face and cross-sectional OCT, and fundus photography. Two masked readers scored images for alterations at the level of the retinal pigment epithelium (RPE), choroid, and choriocapillaris. Laser photocoagulation lesions were classified as deep if choriocapillaris alteration was present on OCTA; lesions were classified as superficial if no choriocapillaris alteration was present on OCTA.
  
  
  
  Optical coherence tomography angiography was found to be useful for evaluation of choriocapillaris alteration underlying regions of laser scarring. Of the 28 analyzed laser scars, 13 were classified as superficial and 15 were classified as deep.
  
  
  
  Optical coherence tomography angiography can be used to visualize choriocapillaris alterations associated with focal laser photocoagulation treatment.
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States 2Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachu.
authors.forename: Emily D
authors.initials: ED
authors.lastname: Cole
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States 3Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.
authors.forename: Eduardo A
authors.initials: EA
authors.lastname: Novais
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States 4Ophthalmic Center Reference (CEROF), Federal University of Goiás, Goiânia, Brazil.
authors.forename: Ricardo N
authors.initials: RN
authors.lastname: Louzada
authors.affiliation: Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
authors.forename: Eric M
authors.initials: EM
authors.lastname: Moult
authors.affiliation: Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States.
authors.forename: Byung-Kun
authors.initials: BK
authors.lastname: Lee
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States.
authors.forename: Andre J
authors.initials: AJ
authors.lastname: Witkin
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States.
authors.forename: Nadia K
authors.initials: NK
authors.lastname: Waheed
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States.
authors.forename: Jay S
authors.initials: JS
authors.lastname: Duker
authors.affiliation: New England Eye Center Tufts University School of Medicine, Boston, Massachusetts, United States.
authors.forename: Caroline R
authors.initials: CR
authors.lastname: Baumal
mesh_terms: D000368:Aged; D002196:Capillaries / Q000473:pathology; D002829:Choroid / Q000098:blood supply* / Q000473:pathology; D003430:Cross-Sectional Studies; D003930:Diabetic Retinopathy / Q000150:complications / Q000175:diagnosis / Q000601:surgery; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D005500:Follow-Up Studies; D005654:Fundus Oculi; D006801:Humans; D017075:Laser Coagulation / Q000379:methods*; D008269:Macular Edema / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D008297:Male; D055213:Retinal Pigment Epithelium / Q000473:pathology; D012171:Retinal Vessels / Q000473:pathology*; D012189:Retrospective Studies; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods*