title: Is there a treatment protocol in which platelet-rich plasma is effective?
abstract: OBJECTIVE
  We aimed to reveal whether there are prospective suggestions for effective and standard platelet-rich plasma applications.
  
  
  METHODS
  We searched for clinical trials and traced all the references of incorporated documents.
  
  
  RESULTS
  In literature, there was no study indicating which disease is treated by which mechanism of action, how much dose and content are prepared and applied, when the treatment is applied and how many cures are applied.
  
  
  CONCLUSIONS
  Guides introducing which concentrations of PRP are used for which diseases are to be prepared immediately by a committee which is comprised of primarily orthopedists, clinical pharmacologists and toxicologists.
authors.affiliation: Republic of Turkey Ministry of Health, State Hospital, Department of Pharmacovigilance, Materiovigilance and Rational Use of Drugs, 59100 Tekirdag, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Yilmaz
authors.affiliation: Pamukkale University School of Medicine, Department of Orthopaedic and Traumatology, 20070 Denizli, Turkey.
authors.forename: Semih
authors.initials: S
authors.lastname: Akkaya
authors.affiliation: Central Hospital Health Group, Department of Orthopaedic and Traumatology, 34742 Istanbul, Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Isyar
authors.affiliation: Istanbul Medipol University School of Medicine, Department of Orthopaedic and Traumatology, 34214 Istanbul, Turkey.
authors.forename: Ahmet Güray
authors.initials: AG
authors.lastname: Batmaz
authors.affiliation: Istanbul Medipol University School of Medicine, Department of Orthopaedic and Traumatology, 34214 Istanbul, Turkey.
authors.forename: Olcay
authors.initials: O
authors.lastname: Guler
authors.affiliation: Istanbul Medipol University School of Medicine, Department of Orthopaedic and Traumatology, 34214 Istanbul, Turkey.
authors.forename: Kadir
authors.initials: K
authors.lastname: Oznam
authors.affiliation: Istanbul Medipol University School of Medicine, Department of Orthopaedic and Traumatology, 34214 Istanbul, Turkey.
authors.forename: Akin
authors.initials: A
authors.lastname: Ugras
authors.affiliation: Memorial Health Group, Department of Orthopaedic and Traumatology, 34384 Istanbul, Turkey.
authors.forename: Mahir
authors.initials: M
authors.lastname: Mahiroğullari
keywords: Epicondylitis; Pain following arthroplasty; Platelet-rich plasma; Proximal hamstring; Rotator cuff damage; Tendinopathy