title: Perioperative Management and Outcome of Bilateral Adrenalectomy in 9 Dogs.
abstract: OBJECTIVE
  To report perioperative care, postoperative management, and long-term outcomes in dogs undergoing bilateral adrenalectomy.
  
  
  METHODS
  Retrospective case series.
  
  
  METHODS
  Dogs undergoing bilateral adrenalectomy from 2008 to 2013 (n=9).
  
  
  METHODS
  Data retrieved from the record, when available, included signalment, preoperative clinical signs, laboratory data, diagnostic imaging, blood pressure measurement, preoperative treatment for adrenal gland disease, intraoperative procedures, treatments and complications, postoperative treatment and diagnostics during hospitalization, diagnostics and management following discharge, histopathologic diagnosis, and survival.
  
  
  RESULTS
  Seven dogs underwent concurrent bilateral adrenalectomy and 2 dogs had staged adrenalectomy. Surgery was uncomplicated in most cases. All dogs received IV dexamethasone SP intraoperatively. Eight dogs received intramuscular desoxycorticosterone pivalate intraoperatively. Histopathology revealed adrenocortical adenoma (7 dogs), adrenocortical carcinoma (4), pheochromocytoma (6), and adrenocortical atrophy (1). One dog died perioperatively and the remainder died due to unrelated causes. Postoperative management of hypoadrenocorticism included oral prednisone and intramuscular desoxycorticosterone pivalate (6 dogs), oral prednisone and fludrocortisone (1), and oral fludrocortisone alone (1). The median survival time in dogs surviving to hospital discharge was 525 days (range 67-966 days). No dogs developed metastatic disease or died due to signs of hypoadrenocorticism.
  
  
  CONCLUSIONS
  Based on the cases reported here, the perioperative mortality in dogs undergoing bilateral adrenalectomy may be lower than previously reported. Management of postoperative hypoadrenocorticism is both achievable and straightforward.
authors.affiliation: Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada.
authors.forename: Michelle L
authors.initials: ML
authors.lastname: Oblak
authors.affiliation: Fitzpatrick Referrals, Guildford, United Kingdom.
authors.forename: Nicholas J
authors.initials: NJ
authors.lastname: Bacon
authors.affiliation: Oakland Veterinary Referral Services, Bloomfield Hills, Michigan.
authors.forename: Jennifer L
authors.initials: JL
authors.lastname: Covey
mesh_terms: D000305:Adrenal Cortex Hormones / Q000627:therapeutic use; D000310:Adrenal Gland Neoplasms / Q000601:surgery; D000315:Adrenalectomy / Q000379:methods / Q000662:veterinary*; D018268:Adrenocortical Carcinoma / Q000601:surgery / Q000662:veterinary*; D000818:Animals; D003900:Desoxycorticosterone / Q000031:analogs & derivatives / Q000627:therapeutic use; D004283:Dog Diseases / Q000601:surgery*; D004285:Dogs; D005260:Female; D005438:Fludrocortisone / Q000627:therapeutic use; D008297:Male; D059035:Perioperative Period / Q000662:veterinary*; D010673:Pheochromocytoma / Q000601:surgery / Q000662:veterinary*; D011241:Prednisone / Q000627:therapeutic use; D012189:Retrospective Studies; D016896:Treatment Outcome
chemical_list: D000305:Adrenal Cortex Hormones; C019323:deoxycortone pivalate; D003900:Desoxycorticosterone; D005438:Fludrocortisone; D011241:Prednisone