title: Management of postprandial glucose: Recommended targets and treatment with biphasic insulin.
abstract: Increases in glycaemia, particularly following meals, have been independently associated with diabetes complications, most notably cardiovascular disease. Control of postprandial plasma glucose (PPG) therefore plays an important role in diabetes management. International diabetes guidelines acknowledge the value of PPG monitoring yet place relatively little emphasis on PPG control. This article considers the impact of suboptimal PPG control and current recommendations with regard to management of PPG. Specific consideration is given to the role of biphasic insulins, one of the treatment options recognised by the International Diabetes Federation as preferentially lowering PPG levels.
authors.affiliation: Department of Internal Medicine, Centre for Diabetes and Metabolism, Fachklinik Bad Heilbrunn, Bad Heilbrunn, Germany. Electronic address: andreas.liebl@fachklinik-bad-heilbrunn.de.
authors.forename: Andreas
authors.initials: A
authors.lastname: Liebl
mesh_terms: D000465:Algorithms; D015415:Biomarkers / Q000097:blood; D061265:Biphasic Insulins / Q000008:administration & dosage* / Q000009:adverse effects; D001786:Blood Glucose / Q000187:drug effects* / Q000378:metabolism; D000066491:Clinical Decision-Making; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000453:epidemiology; D006801:Humans; D007004:Hypoglycemic Agents / Q000008:administration & dosage* / Q000009:adverse effects; D018579:Patient Selection; D019518:Postprandial Period; D017410:Practice Guidelines as Topic; D012307:Risk Factors; D016896:Treatment Outcome
chemical_list: D015415:Biomarkers; D061265:Biphasic Insulins; D001786:Blood Glucose; D007004:Hypoglycemic Agents
keywords: Biphasic insulin aspart; Guidelines for management of diabetes; Management of hyperglycaemia; Postprandial plasma glucose