title: Ebola Virus-Related Encephalitis.
abstract: Ebola patients frequently exhibit behavioral modifications with ideation slowing and aggressiveness, sometimes contrasting with mild severity of Ebola disease. We performed lumbar punctures in 3 patients with this presentation and found Ebola virus in all cerebrospinal fluid samples. This discovery helps to discuss the concept of a specific Ebola virus encephalitis.
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Percy, Clamart.
authors.forename: Thierry
authors.initials: T
authors.lastname: de Greslan
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Bégin, Saint Mandé.
authors.forename: Magali
authors.initials: M
authors.lastname: Billhot
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Clermont Tonnerre, Brest.
authors.forename: Claire
authors.initials: C
authors.lastname: Rousseau
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Percy, Clamart.
authors.forename: Christine
authors.initials: C
authors.lastname: Mac Nab
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Legouest, Metz.
authors.forename: Ludovic
authors.initials: L
authors.lastname: Karkowski
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Percy, Clamart.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Cournac
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Sainte Anne, Toulon.
authors.forename: Julien
authors.initials: J
authors.lastname: Bordes
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Legouest, Metz.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Gagnon
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Robert Picqué, Bordeaux.
authors.forename: Philippe
authors.initials: P
authors.lastname: Dubrous
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Duron
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Laveran, Marseille.
authors.forename: Sophie
authors.initials: S
authors.lastname: Moroge
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Direction Centrale du Service de Santé des Armées, Paris, France.
authors.forename: Benoit
authors.initials: B
authors.lastname: Quentin
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Guinean Military Teaching Hospital, Conakry, Guinea.
authors.forename: Fassou
authors.initials: F
authors.lastname: Koulibaly
authors.affiliation: Hôpital d'Instruction des Armées Percy, Clamart.
authors.forename: Flavie
authors.initials: F
authors.lastname: Bompaire
authors.affiliation: Hôpital d'Instruction des Armées Percy, Clamart.
authors.forename: Jean-Luc
authors.initials: JL
authors.lastname: Renard
authors.affiliation: French Military Ebola Virus Disease Treatment Centre.|Hôpital d'Instruction des Armées Sainte Anne, Toulon.
authors.forename: Gilles
authors.initials: G
authors.lastname: Cellarier
mesh_terms: D000328:Adult; D015415:Biomarkers; D029043:Ebolavirus / Q000235:genetics*; D018792:Encephalitis, Viral / Q000134:cerebrospinal fluid / Q000175:diagnosis* / Q000821:virology*; D005260:Female; D006801:Humans; D008297:Male; D063868:Patient Outcome Assessment; D010641:Phenotype; D012367:RNA, Viral; D060888:Real-Time Polymerase Chain Reaction; D013129:Spinal Puncture; D063189:Symptom Assessment
chemical_list: D015415:Biomarkers; D012367:RNA, Viral
keywords: Ebola virus; behavioral disturbance; encephalitis