title: In Vitro Study of SnS2, BiOCl and SnS2-Incorporated BiOCl Inorganic Nanoparticles Used as Doxorubicin Carrier.
abstract: Inorganic nanoparticles have been widely used in biomedical field. In this paper, we try to study the use of three types of inorganic nanoparticles (i.e., SnS2, BiOCl and SnS2-incorporated BiOCl (SnS2/BiOCl)) as doxorubicin (DOX) carriers. Firstly, SnS2, BiOCl and SnS2/BiOCl were synthesised, then were characterized by TEM, nanoparticles size and zeta potential. Next the drug release and cell viability test were carried out. The cell viability test indicated that the drug carriers can effectively kill HeLa cells while maintaining low cytotoxicity against normal cells-fibroblasts. The results show the potential of SnS2/BiOCl nanoparticles for antitumor applications.
authors.forename: Jiangming
authors.initials: J
authors.lastname: Deng
authors.forename: Yunfei
authors.initials: Y
authors.lastname: Mo
authors.forename: Jianghui
authors.initials: J
authors.lastname: Liu
authors.forename: Rui
authors.initials: R
authors.lastname: Guo
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhang
authors.forename: Wei
authors.initials: W
authors.lastname: Xue
authors.forename: Yuanming
authors.initials: Y
authors.lastname: Zhang
mesh_terms: D001729:Bismuth / Q000737:chemistry*; D002470:Cell Survival / Q000187:drug effects; D004317:Doxorubicin / Q000737:chemistry*; D004337:Drug Carriers / Q000737:chemistry* / Q000633:toxicity; D065546:Drug Liberation; D006367:HeLa Cells; D006801:Humans; D053758:Nanoparticles / Q000737:chemistry* / Q000633:toxicity; D010316:Particle Size; D013440:Sulfides / Q000737:chemistry*; D017971:Tin Compounds / Q000737:chemistry*
chemical_list: D004337:Drug Carriers; D013440:Sulfides; D017971:Tin Compounds; C078041:tin sulfide; C044685:bismuth oxychloride; D004317:Doxorubicin; D001729:Bismuth