title: Association between obesity and lower urinary tract symptoms: propensity score matching study between healthy controls and obese patients seeking bariatric surgery.
abstract: BACKGROUND
  To date, the association between obesity and lower urinary tract symptoms (LUTS) is controversial.
  
  
  OBJECTIVE
  To overcome the current inconsistent results regarding the association between obesity and LUTS and to investigate the association between obesity and LUTS using propensity score matching analysis.
  
  
  METHODS
  Bariatric center of excellence and health promotion center at university hospital.
  
  
  METHODS
  From August 2012 to December 2014, a total of 260 obese patients (77 men and 180 women) visited to our bariatric center to undergo bariatric surgery. Patients' International Prostate Symptom Score (IPSS) and overactive bladder symptom score were compared with those of 844 healthy controls who had visited our health center during the same period. To control for the effects of age, 1:1 propensity score matching was used.
  
  
  RESULTS
  After matching propensity score forage, 73 male patients and 176 female patients were included in our study. In men, all IPSS items except "frequency" were significantly different between obese patients and controls; median scores were higher in the obese group. In women, all IPSS items except "feeling of incomplete emptying" were significantly different between the 2 groups. Both voiding and storage subscores also had marked differences in both genders (P<.001). Total IPSS, quality of life, and total overactive bladder symptom score were significantly different in both genders (P< .001).
  
  
  CONCLUSIONS
  There were marked differences in LUTS between obese and nonobese patients, including in voiding and storage symptoms. Considering the relatively young age of both groups, this case-control study supports the hypothesis of a relationship between obesity and bladder pathophysiology.
authors.affiliation: Department of Urology, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.
authors.forename: Jae Heon
authors.initials: JH
authors.lastname: Kim
authors.affiliation: Department of Biostatistics, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.
authors.forename: Hwa Yeon
authors.initials: HY
authors.lastname: Sun
authors.affiliation: Department of Biostatistics, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.
authors.forename: Soo Yeon
authors.initials: SY
authors.lastname: Park
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea.
authors.forename: Min Ju
authors.initials: MJ
authors.lastname: Soh
authors.affiliation: Department of Surgery, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea. Electronic address: yjgs1997@gmail.com.
authors.forename: Yong Jin
authors.initials: YJ
authors.lastname: Kim
authors.affiliation: Department of Urology, Soonchunhyang University Hospital, College of Medicine, Soonchunhyang University, Seoul, Korea. Electronic address: yssong@schmc.ac.kr.
authors.forename: Yun Seob
authors.initials: YS
authors.lastname: Song
mesh_terms: D000328:Adult; D050110:Bariatric Surgery; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D059411:Lower Urinary Tract Symptoms / Q000209:etiology* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009767:Obesity, Morbid / Q000150:complications* / Q000503:physiopathology / Q000601:surgery; D057216:Propensity Score; D011788:Quality of Life; D053201:Urinary Bladder, Overactive / Q000209:etiology / Q000503:physiopathology; D014554:Urination / Q000502:physiology
keywords: Bariatric surgery; Lower urinary tract symptoms; Obesity