title: Unusual alkaloids of the highland species Astragalus cryptanthus Wedd. (Fabaceae).
abstract: Two unusual caprolactam alkaloids, 3-(dimethylamino)hexahydro-2H-azepin-2-one and 3-(methylamino)-hexahydro-2H-azepin-2-one, were isolated from the aerial parts of Astragalus cryptanthus Wedd.; their structures were unambiguously determined based on data from extensive 1D and 2D NMR, GC-MS and FT-IR spectroscopic analyses. This is the first report of this alkaloid type in the genus Astragalus.
authors.affiliation: a Laboratorio de Química Ecológica, Facultad de Ciencias, Departamento de Ciencias Ecológicas , Universidad de Chile , Santiago , Chile.
authors.forename: Javier
authors.initials: J
authors.lastname: Echeverría
authors.affiliation: a Laboratorio de Química Ecológica, Facultad de Ciencias, Departamento de Ciencias Ecológicas , Universidad de Chile , Santiago , Chile.
authors.forename: Sergio M
authors.initials: SM
authors.lastname: Espinoza
authors.affiliation: a Laboratorio de Química Ecológica, Facultad de Ciencias, Departamento de Ciencias Ecológicas , Universidad de Chile , Santiago , Chile.
authors.forename: Hermann M
authors.initials: HM
authors.lastname: Niemeyer
mesh_terms: D000470:Alkaloids / Q000737:chemistry; D027883:Astragalus Plant / Q000737:chemistry*; D002209:Caprolactam / Q000031:analogs & derivatives* / Q000737:chemistry; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: C000618254:3-(dimethylamino)hexahydro-2H-azepin-2-one; C000618255:3-(methylamino)-hexahydro-2H-azepin-2-one; D000470:Alkaloids; D002209:Caprolactam
keywords: Astragalus cryptanthus; Fabaceae; caprolactam alkaloids