title: Pythiosis in the Nasal Cavity of Horses.
abstract: Two cases of nasal pythiosis are reported in horses from the semi-arid region of northeastern Brazil. From January 1986 to December 2015, the Laboratory of Animal Pathology, Federal University of Campina Grande received 830 equine samples, 156 (18.79%) of which were diagnosed with pythiosis. Of these, two horses (1.28%), a male and a female adult cross-breed, had lesions in the nasal cavity. Both horses had access to water reservoirs. Clinically, they had swelling in the rhinofacial region and a serosanguineous nasal discharge. Macroscopically, in case 1, the lesion affected the nasal vestibule, extending to the alar cartilage and nasal septum. In case 2, the lesion extended through the turbinates and the meatuses of the nasal cavity, as well as the ethmoid region. In both cases, the lesions were characterized by having a yellow-grey granular surface with cavitations of different sizes containing coral-like masses of necrotic tissue (kunkers). Histologically, multifocal necrotizing eosinophilic rhinitis associated with hyphae (2-8 μm) similar to Pythium insidiosum were observed. In case 2, the lesions extended to the muscle, cartilage and bone adjacent to the nasal cavity and lungs. The diagnosis was confirmed by immunohistochemistry. It is concluded that nasal pythiosis occurs sporadically in horses in the semi-arid region of northeastern Brazil where cutaneous pythiosis is prevalent.
authors.affiliation: Laboratory of Veterinary Pathology, Universidade Federal de Campina Grande, Patos, PB, Brazil.
authors.forename: E P F
authors.initials: EPF
authors.lastname: Souto
authors.affiliation: Laboratory of Veterinary Pathology, Universidade Federal de Campina Grande, Patos, PB, Brazil.
authors.forename: L A
authors.initials: LA
authors.lastname: Maia
authors.affiliation: Laboratory of Veterinary Pathology, Universidade Federal de Campina Grande, Patos, PB, Brazil.
authors.forename: R G
authors.initials: RG
authors.lastname: Olinda
authors.affiliation: Laboratory of Veterinary Pathology, Universidade Federal de Campina Grande, Patos, PB, Brazil.
authors.forename: G J N
authors.initials: GJN
authors.lastname: Galiza
authors.affiliation: Pathology Department, Universidade Federal de Santa Maria, Santa Maria, Rio Grande do Sul, Brazil.
authors.forename: G D
authors.initials: GD
authors.lastname: Kommers
authors.affiliation: Medical Clinic for Large Animals, Universidade Federal de Campina Grande, Patos, PB, Brazil.
authors.forename: E G
authors.initials: EG
authors.lastname: Miranda-Neto
authors.affiliation: Laboratory of Veterinary Pathology, Universidade Federal de Campina Grande, Patos, PB, Brazil.
authors.forename: A F M
authors.initials: AFM
authors.lastname: Dantas
authors.affiliation: Laboratory of Veterinary Pathology, Universidade Federal de Campina Grande, Patos, PB, Brazil. Electronic address: franklin.riet@pq.cnpq.br.
authors.forename: F
authors.initials: F
authors.lastname: Riet-Correa
mesh_terms: D000818:Animals; D005260:Female; D006734:Horse Diseases / Q000382:microbiology* / Q000473:pathology*; D006736:Horses; D008297:Male; D009296:Nasal Cavity / Q000473:pathology; D009668:Nose Diseases / Q000382:microbiology* / Q000473:pathology*; D058968:Pythiosis / Q000473:pathology*
keywords: Pythium spp.; horse; rhinitis