title: [Calciphylaxis. A review of 9 cases].
abstract: OBJECTIVE
  Calciphylaxis is a cutaneous ischaemic vascular disease of small vessels with high morbidity and mortality. To date very few series of patients with this disease have been published, none from a Spanish hospital. The main objectives of this work are to analyze the demographic, clinical and histological profile of patients diagnosed in our department to identify risk factors and potential therapeutic strategies.
  
  
  METHODS
  We made a retrospective study of the cases seen in the dermatology department with a diagnosis of calciphylaxis and who had a confirmatory biopsy in the period between January 2010 to August 2015.
  
  
  RESULTS
  Nine patients were studied, with an age range of 76-86 years. All had cardiovascular comorbidities and 67% had renal failure. A 33% mortality was observed.
  
  
  CONCLUSIONS
  Faced with a possible diagnosis of calciphylaxis, a complete blood analysis is mandatory to rule out other causes of skin ulcers. The management of these patients should be undertaken by a multidisciplinary team. We emphasize the role of sodium thiosulfate in the treatment of this condition.
authors.affiliation: Servicio de Dermatología, Complejo Hospitalario de Navarra, Pamplona, España. Electronic address: leyre.loidi.pascual@navarra.es.
authors.forename: Leire
authors.initials: L
authors.lastname: Loidi Pascual
authors.affiliation: Servicio de Dermatología, Complejo Hospitalario de Navarra, Pamplona, España.
authors.forename: Ana
authors.initials: A
authors.lastname: Valcayo Peñalba
authors.affiliation: Servicio de Dermatología, Complejo Hospitalario de Navarra, Pamplona, España.
authors.forename: Saioa
authors.initials: S
authors.lastname: Oscoz Jaime
authors.affiliation: Servicio de Anatomía Patológica, Complejo Hospitalario de Navarra, Pamplona, España.
authors.forename: Alicia
authors.initials: A
authors.lastname: Córdoba Iturriagagoitia
authors.affiliation: Servicio de Medicina Interna, Complejo Hospitalario de Navarra, Pamplona, España.
authors.forename: Raquel
authors.initials: R
authors.lastname: Rodil Fraile
authors.affiliation: Servicio de Dermatología, Complejo Hospitalario de Navarra, Pamplona, España.
authors.forename: Juan Ignacio
authors.initials: JI
authors.lastname: Yanguas Bayona
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002115:Calciphylaxis / Q000175:diagnosis* / Q000209:etiology / Q000473:pathology / Q000628:therapy; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D012189:Retrospective Studies; D012307:Risk Factors
keywords: Calcifilaxia; Calciphylaxis; Hiperparatiroidismo; Hyperparathyroidism; Skin ulcer; Sodium thiosulfate; Tiosulfato sódico; Úlcera cutánea