title: Alveococcosis of the liver - strategy of surgical treatment with special focus on liver transplantation.
abstract: BACKGROUND
  Echinococcosis is a zoonosis caused by infestation with any of 4 (of the 16) members of the Echinococcus genus, namely Echinococcus granulosus, Echinococcus multilocularis, Echinococcus oligarthus, and Echinococcus vogelii. The aim of this retrospective analysis was to present the outcomes of patients undergoing liver resection and liver transplantation (LT) for E. multilocularis infection.
  
  
  METHODS
  A total of 44 patients who underwent surgical treatment of E. multilocularis infection in the period between 1989 and 2014 were included in the study cohort and retrospectively analyzed.
  
  
  RESULTS
  LT was performed in 22 patients (50.0%), including 4 of 26 patients undergoing initial non-transplant management. Non-transplant procedures comprised liver resection in 23 patients (88.5%), diagnostic laparoscopy in 2 (7.7%), and left adrenalectomy in 1 patient (3.8%). Post-transplantation survival rates were 90%, 85%, and 75% at 1, 5, and 10 years, respectively.
  
  
  CONCLUSIONS
  In conclusion, LT for E. multilocularis infection is a safe and effective treatment method.
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland. wpatek@mp.pl.
authors.forename: W
authors.initials: W
authors.lastname: Patkowski
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Kotulski
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: P
authors.initials: P
authors.lastname: Remiszewski
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Grąt
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Zieniewicz
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: K
authors.initials: K
authors.lastname: Kobryń
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Najnigier
authors.affiliation: Department of Pathology, Medical University of Warsaw, Warsaw, Poland.
authors.forename: B
authors.initials: B
authors.lastname: Ziarkiewicz-Wróblewska
authors.affiliation: Department of General, Transplant and Liver Surgery, Medical University of Warsaw, Warsaw, Poland.
authors.forename: M
authors.initials: M
authors.lastname: Krawczyk
mesh_terms: D000315:Adrenalectomy; D000818:Animals; D004444:Echinococcosis, Hepatic / Q000000981:diagnostic imaging / Q000401:mortality* / Q000469:parasitology / Q000601:surgery*; D048210:Echinococcus multilocularis / Q000302:isolation & purification*; D006498:Hepatectomy; D006801:Humans; D010535:Laparoscopy; D016031:Liver Transplantation / Q000009:adverse effects* / Q000379:methods; D012189:Retrospective Studies; D015996:Survival Rate; D014057:Tomography, X-Ray Computed; D016896:Treatment Outcome; D015047:Zoonoses / Q000000981:diagnostic imaging / Q000401:mortality* / Q000469:parasitology / Q000601:surgery*
keywords: 
  Echinococcus multilocularis
  ; alveococcosis; liver resection; liver transplantation; outcomes