title: Cardiac involvement in juvenile idiopathic arthritis.
abstract: An insidious progression of cardiovascular (CV) involvement is generally associated with rheumatologic diseases and finally regarded as a major source of morbidity and mortality in Juvenile idiopathic arthritis (JIA) patients. JIA could involve all of the cardiac structures, including pericardium, myocardium, endocardium; coronary vessels; valves and conduction system. Development of pericarditis, myocarditis, endocarditis and ventricular dysfunction are not unexpected issues in the progress of JIA. It is essential to ensure a comprehensive follow-up with advanced and up-to-date diagnostic and therapeutic modalities for prevention of CV complications in JIA patients. Since these are all associated with an unfavorable prognosis, it is necessary to detect subclinical cardiac involvement in CV asymptomatic patients, in order to start adequate management and treatment. Furthermore, controlling chronic inflammatory state of JIA by new treatment modalities will also significantly reduce the overall morbidity and mortality related to CV diseases. In this review, we aimed to investigate CV involvement patterns in patients with JIA.
authors.affiliation: Department of Pediatric Cardiology, Elazig Training and Research Hospital, Elazig, Turkey.
authors.forename: Bulent
authors.initials: B
authors.lastname: Koca
authors.affiliation: Department of Pediatric Rheumatology, Cerrahpasa Medical School, Atakoy 1. Kisim D-43/8, 34750, Istanbul, Turkey.
authors.forename: Sezgin
authors.initials: S
authors.lastname: Sahin
authors.affiliation: Department of Pediatric Rheumatology, Cerrahpasa Medical School, Atakoy 1. Kisim D-43/8, 34750, Istanbul, Turkey.
authors.forename: Amra
authors.initials: A
authors.lastname: Adrovic
authors.affiliation: Department of Pediatric Rheumatology, Cerrahpasa Medical School, Atakoy 1. Kisim D-43/8, 34750, Istanbul, Turkey.
authors.forename: Kenan
authors.initials: K
authors.lastname: Barut
authors.affiliation: Department of Pediatric Rheumatology, Cerrahpasa Medical School, Atakoy 1. Kisim D-43/8, 34750, Istanbul, Turkey. ozgurkasapcopur@hotmail.com.
authors.forename: Ozgur
authors.initials: O
authors.lastname: Kasapcopur
mesh_terms: D001145:Arrhythmias, Cardiac / Q000209:etiology* / Q000503:physiopathology; D001171:Arthritis, Juvenile / Q000150:complications* / Q000503:physiopathology; D002318:Cardiovascular Diseases / Q000209:etiology* / Q000503:physiopathology; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans
keywords: Cardiovascular disease; Cardiovascular risk factors; Juvenile idiopathic arthritis; Pericardial disease; Valvular disease