title: Magnesium Status and Its Association with Oxidative Stress in Obese Women.
abstract: The aim of this study was to assess the relationship between magnesium status and oxidative stress in obese and nonobese women. This cross-sectional study included 83 women, aged between 20 and 50 years, who were divided into two groups: the obese group (n = 31) and the control group (n = 52). The control group was age-matched with the obese group. Magnesium intake was monitored using 3-day food records and NutWin software version 1.5. The plasma and erythrocyte magnesium concentrations were determined by flame atomic absorption spectrophotometry. Plasma levels of thiobarbituric acid reactive substances (TBARS) were determined as biomarkers for lipid peroxidation and therefore of oxidative stress. The mean values of the magnesium content in the diet were found to be lower than those recommended, though there was no significant difference between groups (p > 0.05). The mean concentrations of plasma and erythrocyte magnesium were within the normal range, with no significant difference between groups (p > 0.05). The mean concentration of plasma TBARS was higher in obese woman, and the difference between the groups was statistically different (p < 0.05). There was a positive correlation between erythrocyte magnesium and plasma TBARS in the obese group (p = 0.021). Obese patients ingest low dietary magnesium content, which does not seem to affect the plasma and erythrocyte concentrations of the mineral. The study showed a negative correlation between erythrocyte magnesium concentrations and plasma TBARS, suggesting the influence of magnesium status on the parameters of oxidative stress in obese women.
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Jennifer Beatriz Silva
authors.initials: JBS
authors.lastname: Morais
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Juliana Soares
authors.initials: JS
authors.lastname: Severo
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Ana Raquel Soares
authors.initials: ARS
authors.lastname: de Oliveira
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Kyria Jayanne Clímaco
authors.initials: KJC
authors.lastname: Cruz
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Thaline Milany
authors.initials: TM
authors.lastname: da Silva Dias
authors.affiliation: Department of Biochemistry and Pharmacology, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil.
authors.forename: Régina Célia
authors.initials: RC
authors.lastname: de Assis
authors.affiliation: Department of Food and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, Butantã, São Paulo, São Paulo, Brazil.
authors.forename: Célia
authors.initials: C
authors.lastname: Colli
authors.affiliation: Department of Nutrition, Federal University of Piauí, Campus Minister Petrônio Portela, Ininga, Teresina, Piauí, Brazil. dilina.marreiro@gmail.com.|, 665, Hugo Napoleão St., Ed. Palazzo Reale, Apt°. 2001, Jóquei, Teresina, Piauí, 64048-320, Brazil. dilina.marreiro@gmail.com.
authors.forename: Dilina
authors.initials: D
authors.lastname: do Nascimento Marreiro
mesh_terms: D000328:Adult; D003430:Cross-Sectional Studies; D019587:Dietary Supplements; D004912:Erythrocytes / Q000378:metabolism*; D005260:Female; D006801:Humans; D015227:Lipid Peroxidation / Q000187:drug effects*; D008274:Magnesium / Q000008:administration & dosage / Q000493:pharmacokinetics; D008875:Middle Aged; D009765:Obesity / Q000097:blood*; D018384:Oxidative Stress / Q000187:drug effects*
chemical_list: D008274:Magnesium
keywords: Magnesium; Nutritional status; Obesity; Oxidative stress