title: Intravenous Tigecycline Facilitates Cure of Severe Clostridium difficile Infection (CDI) After Failure of Standard Therapy: A Case Report and Literature Review of Tigecycline Use in CDI.
abstract: Standard treatment for severe Clostridium difficile infection (CDI) is oral vancomycin with metronidazole. After failure of this standard regimen, treatment becomes challenging. A young woman treated for septic shock developed CDI. Standard treatment failed and she was ineligible for fecal transplant. Addition of tigecycline to her regimen resulted in cure.
authors.affiliation: Division of Infectious Diseases , Wayne State University School of Medicine, Harper University Hospital , Detroit, Michigan.
authors.forename: Bhagyashri D
authors.initials: BD
authors.lastname: Navalkele
authors.affiliation: Division of Infectious Diseases , Wayne State University School of Medicine, Harper University Hospital , Detroit, Michigan.
authors.forename: Stephen A
authors.initials: SA
authors.lastname: Lerner
keywords: Clostridium difficile; severe Clostridium difficile; tigecycline