title: Ten-year changes in health-related quality of life after biliopancreatic diversion with duodenal switch.
abstract: BACKGROUND
  Long-term data on health-related quality of life (HRQL) after biliopancreatic diversion with duodenal switch (BPDDS) are scarce. The aim of this study was to evaluate changes in HRQL from baseline to 10 years in patients who had undergone BPDDS.
  
  
  METHODS
  We included 50 patients who underwent BPDDS for severe obesity at Førde Central Hospital in a prospective cohort study. HRQL was measured with a self-report questionnaire, the Short-Form-36. Main outcomes were the physical component score and the mental component score. HRQL was assessed before surgery and after 1, 2, 5, and 10 years. Linear mixed-effect models were applied to evaluate changes over time.
  
  
  RESULTS
  A total of 35 patients (70%) completed the 10-year follow-up of the HRQL study. The mean body mass index at baseline was 51.7 kg/m2(95 % CI, 50.0-53.5) and 34.3 kg/m2(95% CI, 32.4-36.2) at 10 years. The physical component score improved significantly from 32.6 (95% CI, 29.7-35.5) at baseline to 44.2 (95% CI, 40.9-47.5) at the 10-year follow-up (P<.001). Mental component scores also improved significantly, from 37.8 (95% CI, 34.2-41.3) at baseline to 46.0 (95% CI, 41.9-50.0) at the 10-year follow-up (P<.001). However, the scores at 10-year follow-up were significantly lower than the Norwegian norm data.
  
  
  CONCLUSIONS
  Ten years after BPDDS, patients' HRQL was significantly improved from preoperative values, and approximately 60% of the improvements seen at 1-year follow-up were maintained.
authors.affiliation: Faculty of Health Studies, Sogn og Fjordane University College, Førde, Norway; Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway. Electronic address: anny.aasprang@hisf.no.
authors.forename: Anny
authors.initials: A
authors.lastname: Aasprang
authors.affiliation: Faculty of Health Studies, Sogn og Fjordane University College, Førde, Norway; Centre of Health Research, Førde Hospital Trust, Førde, Norway.
authors.forename: John Roger
authors.initials: JR
authors.lastname: Andersen
authors.affiliation: Department of Surgery, Voss Hospital, Helse Bergen Health Trust, Voss, Norway.
authors.forename: Villy
authors.initials: V
authors.lastname: Våge
authors.affiliation: Faculty of Health Studies, Sogn og Fjordane University College, Førde, Norway; Centre of Health Research, Førde Hospital Trust, Førde, Norway; Obesity and Quality of Life Consulting, Durham, North Carolina; Duke University School of Medicine, Durham, North Carolina.
authors.forename: Ronette
authors.initials: R
authors.lastname: Kolotkin
authors.affiliation: Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.
authors.forename: Gerd Karin
authors.initials: GK
authors.lastname: Natvig
mesh_terms: D000293:Adolescent; D000328:Adult; D015904:Biliopancreatic Diversion / Q000379:methods*; D015992:Body Mass Index; D004386:Duodenum / Q000601:surgery*; D005260:Female; D006304:Health Status; D006801:Humans; D008297:Male; D008603:Mental Health; D008875:Middle Aged; D009767:Obesity, Morbid / Q000523:psychology / Q000601:surgery; D011182:Postoperative Care; D011446:Prospective Studies; D011788:Quality of Life; D011795:Surveys and Questionnaires; D016896:Treatment Outcome; D055815:Young Adult
keywords: BMI; Bariatric surgery; Body mass index; Health status survey; Health-related quality of life; Obesity; Obesity surgery; SF-36; Short Form -36