title: Genetic polymorphism of 22 autosomal STR markers in a Han population of Southern China.
abstract: Population genetic data and forensic statistics of 22 autosomal short tandem repeat (STR) loci (D1S1656, D2S1338, D3S3045, D4S2366, D5S2500, D6S477, D7S3048, D8S1132, D9S925, D10S1435, D11S2368, D12S391, D13S325, D14S608, D15S659, D16S539, D17S1290, D18S535, D19S253, D20S470, D21S1270 and GATA198B05) were determined for a sample of 515 unrelated individuals from Han population in Southern China. The expected heterozygosity and the discrimination power varied from 0.7358 to 0.8733 and 0.8915 to 0.9702, respectively. The probability of excluding an unrelated man as the true father (assuming no background relatedness in the population) for trios and for duos ranged from 0.5126 to 0.7415 and 0.3331 to 0.5864, respectively. The studied STRs appear to provide a significant improvement in the statistical power of kinship analysis.
authors.affiliation: Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: liuql@mail.sysu.edu.cn.
authors.forename: Qiu-Ling
authors.initials: QL
authors.lastname: Liu
authors.affiliation: Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: lanczx@163.com.
authors.forename: Zi-Xiang
authors.initials: ZX
authors.lastname: Chen
authors.affiliation: Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: mr_ccg@126.com.
authors.forename: Chu-Guang
authors.initials: CG
authors.lastname: Chen
authors.affiliation: Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China; Suzhou Microread Genetics Co., Ltd., China, Room 312, No.15 Building, Biomedical Engineering Park, No.8 Jinfeng Road, SND, Suzhou 215163, Jiangsu, PR China; Faculty of Forensic Medicine, Zhongshan Medical School of Sun Yat-Sen University, 74 Zhongshan 2nd Road, Guangzhou 510080, PR China. Electronic address: lvdejian@mail.sysu.edu.cn.
authors.forename: De-Jian
authors.initials: DJ
authors.lastname: Lu
mesh_terms: D002681:China; D016172:DNA Fingerprinting; D005006:Ethnicity / Q000235:genetics*; D005787:Gene Frequency; D005819:Genetic Markers; D005828:Genetics, Population; D006801:Humans; D018895:Microsatellite Repeats; D011110:Polymorphism, Genetic
chemical_list: D005819:Genetic Markers
keywords: Chinese Han population; Kinship analysis; Linkage disequilibrium; Population data; Short tandem repeats (STR)