title: Biochemical and synthetic biology approaches to improve photosynthetic CO2-fixation.
abstract: There is an urgent need to improve agricultural productivity to secure future food and biofuel supply. Here, we summarize current approaches that aim at improving photosynthetic CO2-fixation. We critically review, compare and comment on the four major lines of research towards this aim, which focus on (i) improving RubisCO, the CO2-fixing enzyme in photosynthesis, (ii) implementing CO2-concentrating mechanisms, (iii) establishing synthetic photorespiration bypasses, and (iv) engineering synthetic CO2-fixation pathways.
authors.affiliation: Max Planck Institute for Terrestrial Microbiology, Biochemistry & Synthetic Biology of Microbial Metabolism Group, Karl-von-Frisch-Str. 10, 35043 Marburg, Germany; LOEWE Center for Synthetic Microbiology (SYNMIKRO), Philipps University Marburg, 35043 Marburg, Germany. Electronic address: toerb@mpi-marburg.mpg.de.
authors.forename: Tobias J
authors.initials: TJ
authors.lastname: Erb
authors.affiliation: Max Planck Institute for Terrestrial Microbiology, Biochemistry & Synthetic Biology of Microbial Metabolism Group, Karl-von-Frisch-Str. 10, 35043 Marburg, Germany.
authors.forename: Jan
authors.initials: J
authors.lastname: Zarzycki
mesh_terms: D002245:Carbon Dioxide / Q000378:metabolism*; D002384:Catalysis; D010788:Photosynthesis; D012273:Ribulose-Bisphosphate Carboxylase / Q000378:metabolism; D058615:Synthetic Biology
chemical_list: D002245:Carbon Dioxide; D012273:Ribulose-Bisphosphate Carboxylase