title: Clinical Application of Multicolor Imaging Technology.
abstract: OBJECTIVE
  To assess the clinical application of multicolor imaging by confocal scanning laser ophthalmoscopy (cSLO).
  
  
  METHODS
  Retinal imaging was performed in 76 patients including cSLO multicolor imaging (SPECTRALIS SD-OCT, Heidelberg Engineering, Heidelberg, Germany) and color fundus photography (CFP).
  
  
  RESULTS
  The use of confocal optics, reduced light scatter and automated eye tracking enable high-resolution cSLO reflectance images. Compared to CFP, the appearance of pigment alterations and hemorrhages were some of the differences observed. Various artifacts including those derived from optical media alterations need to be considered when interpreting images. Specific pathological findings including epiretinal membranes, fibrovascular proliferations, and reticular pseudodrusen may be better visualized on multicolor images.
  
  
  CONCLUSIONS
  When using multicolor imaging, ophthalmologists need to be mindful about differences in the appearance of pathological changes and artifacts. Multicolor imaging may offer information over and above conventional CFP; it can be performed through undilated pupils and is less affected by media opacities.
authors.affiliation: Department of Ophthalmology, University of Bonn, Bonn, Germany.
authors.forename: Anna C S
authors.initials: AC
authors.lastname: Tan
authors.forename: Monika
authors.initials: M
authors.lastname: Fleckenstein
authors.forename: Steffen
authors.initials: S
authors.lastname: Schmitz-Valckenberg
authors.forename: Frank G
authors.initials: FG
authors.lastname: Holz
mesh_terms: D003952:Diagnostic Imaging / Q000379:methods*; D005451:Fluorescein Angiography / Q000379:methods; D005654:Fundus Oculi; D006801:Humans; D009887:Ophthalmoscopy / Q000379:methods; D055095:Optics and Photonics; D010781:Photography / Q000379:methods; D012160:Retina / Q000473:pathology*; D015593:Retinal Drusen / Q000175:diagnosis*; D055213:Retinal Pigment Epithelium / Q000473:pathology; D041623:Tomography, Optical Coherence / Q000379:methods