title: ASSOCIATION OF MEAN PLATELET VOLUME AND THE MONOCYTE/LYMPHOCYTE RATIO WITH BRUCELLA-CAUSED EPIDIDYMO-ORCHITIS.
abstract: We evaluated the association between the mean platelet volume (MPV) and monocyte/lymphocyte ratio (MLR) with brucella-caused epididymo-orchitis to determine if they could be used to differentiate between brucella and non-brucella epididymo-orchitis. The charts of 88 patients with non-brucella and 14 patients with brucella epididymo-orchitis were retrospectively reviewed. Brucellosis was diagnosed by isolating Brucella spp from a blood culture or from a serum agglutination titer ≥ 1:160 along with accompanying clinical findings. The patients with brucella epididymo-orchitis were significantly more likely to have a lower MPV and a higher MLR than those with non-brucella epididymo-orchitis. Using a MPV cut-off level of less than 9.25 fl to differentiate brucella from non-brucella epididymo-orchitis gives a sensitivity of 78.6%, a specifity of 78.4%, a positive predictive value of 36.7% and a negative predictive value of 95.8%. Using a MLR cut-off level of greater than 0.265 to differentiate brucella from non-brucella epididymo-orchitis gives a sensitivity of 71.4%, a specifity of 65.9%, a positive predictive value of 25% and a negative predictive value of 93.5.%. MPV and MLR values may assist in differentiating between brucella and non-brucella epididymo-orchitis.
authors.forename: Emsal
authors.initials: E
authors.lastname: Aydin
authors.forename: Mert Ali
authors.initials: MA
authors.lastname: Karadag
authors.forename: Kursat
authors.initials: K
authors.lastname: Cecen
authors.forename: Gulsen
authors.initials: G
authors.lastname: Cigsar
authors.forename: Sergulen
authors.initials: S
authors.lastname: Aydin
authors.forename: Aslan
authors.initials: A
authors.lastname: Demir
authors.forename: Murat
authors.initials: M
authors.lastname: Bagcioglu
authors.forename: Umit Yener
authors.initials: UY
authors.lastname: Tekdogan
mesh_terms: D000293:Adolescent; D000328:Adult; D002006:Brucellosis / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D004823:Epididymitis / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D006801:Humans; D008214:Lymphocytes / Q000276:immunology; D008297:Male; D063847:Mean Platelet Volume; D008875:Middle Aged; D009000:Monocytes / Q000276:immunology; D009920:Orchitis / Q000453:epidemiology / Q000276:immunology / Q000503:physiopathology; D011237:Predictive Value of Tests; D012189:Retrospective Studies; D055815:Young Adult