title: Maternal and perinatal outcomes in women with and without hypertensive syndromes submitted to induction of labor with misoprostol.
abstract: OBJECTIVE
  To determine maternal and perinatal outcomes according to the mode of delivery in normotensive and hypertensive women bearing a live, full-term fetus, who were submitted to labor induction with misoprostol.
  
  
  METHODS
  Retrospective cohort study. The endpoints were tachysystole, uterine hyperstimulation, indications for cesarean section, severe maternal morbidity, side effects, maternal death, 1st/5th minute Apgar, neonatal death, requirement for neonatal intensive care, and birth weight (grams). The chi-square or Fisher's exact test was applied at a significance level of 5%. Risk ratios (RRs) and their 95% confidence intervals (95% CI) were calculated.
  
  
  RESULTS
  No significant differences were found in maternal outcome as a function of mode of delivery. First-minute Apgar score <7 was less common with vaginal deliveries in normotensive women (RR = 0.41; 95% CI: 0.18-0.90), this being the only significant difference in perinatal outcome.
  
  
  CONCLUSIONS
  Maternal and perinatal outcomes were similar in hypertensive and normotensive women submitted to labor induction with misoprostol.
authors.affiliation: a Medical Resident in Obstetrics and Gynecology, Instituto de Medicina Integral Prof. Fernando Figueira , Recife , Pernambuco , Brazil.
authors.forename: Rossana Mariana Carvalho
authors.initials: RM
authors.lastname: de Paiva Marques
authors.affiliation: b Department of Obstetrics and Gynecology , Instituto de Medicina Integral Prof. Fernando Figueira , Recife , Pernambuco , Brazil.|c Department of Maternal and Child Healthcare , Federal University of Pernambuco , Recife , Pernambuco , Brazil.|d Department of Obstetrics , Barão de Lucena Hospital , Recife , Pernambuco , Brazil.|e Department of Obstetrics , Arnaldo Marques Polyclinic and Maternity Hospital , Recife , Pernambuco , Brazil.
authors.forename: Alex Sandro Rolland
authors.initials: AS
authors.lastname: Souza
authors.affiliation: f Department of Maternal and Child Healthcare , Federal University of Ceará , Fortaleza , Ceará , Brazil.
authors.forename: Francisco Edson
authors.initials: FE
authors.lastname: de Lucena Feitosa
authors.affiliation: b Department of Obstetrics and Gynecology , Instituto de Medicina Integral Prof. Fernando Figueira , Recife , Pernambuco , Brazil.|d Department of Obstetrics , Barão de Lucena Hospital , Recife , Pernambuco , Brazil.
authors.forename: Aurélio Antônio Ribeiro
authors.initials: AA
authors.lastname: da Costa
authors.affiliation: b Department of Obstetrics and Gynecology , Instituto de Medicina Integral Prof. Fernando Figueira , Recife , Pernambuco , Brazil.|g Department of Maternal and Child Healthcare , Federal University of Campina Grande, Campina Grande , Paraíba , Brazil.
authors.forename: Melania Maria Ramos
authors.initials: MM
authors.lastname: Amorim
mesh_terms: D000293:Adolescent; D000328:Adult; D016208:Databases, Factual; D005260:Female; D006801:Humans; D046110:Hypertension, Pregnancy-Induced; D007231:Infant, Newborn; D007751:Labor, Induced / Q000379:methods*; D008297:Male; D016595:Misoprostol / Q000627:therapeutic use*; D010120:Oxytocics / Q000627:therapeutic use*; D011247:Pregnancy; D011256:Pregnancy Outcome; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D010120:Oxytocics; D016595:Misoprostol
keywords: Childbirth; hypertensive syndromes; induction of labor; labor; misoprostol