title: Seeing is Believing in Ribosome Assembly.
abstract: Many proteins have been implicated genetically and biochemically in the assembly of eukaryotic ribosomes. Now, Kornprobst et al. show us how they are put together with a cryoEM structure of the 90S processome that initiates ribosome assembly, revealing the arrangement of U3 RNA and the several UTP complexes that form a chaperone-like structure around and within the developing 40S ribosomal subunit.
authors.affiliation: Department of Cell Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Electronic address: jon.warner@einstein.yu.edu.
authors.forename: Jonathan R
authors.initials: JR
authors.lastname: Warner
mesh_terms: D018832:Molecular Chaperones; D012322:RNA Precursors; D012269:Ribosomal Proteins; D054682:Ribosome Subunits, Small, Eukaryotic / Q000378:metabolism; D012270:Ribosomes / Q000737:chemistry*; D029701:Saccharomyces cerevisiae Proteins
chemical_list: D018832:Molecular Chaperones; D012322:RNA Precursors; D012269:Ribosomal Proteins; D029701:Saccharomyces cerevisiae Proteins