title: Desensitization to Mycofenolate Mofetil: a novel 12 step protocol.
abstract: The use of MMF has become standard practice in many solid organ transplant recipients due its efficacy and favorable risk profile compared to other immunosuppressants. There has been a single case report of successful MMF desensitization. However, this protocol did not follow current Drug practice parameters. We report a successful desensitization to MMF in a double heart-kidney transplant recipient.
authors.affiliation: Cleveland Clinic, Cleveland, OH, USA.
authors.forename: M
authors.initials: M
authors.lastname: Smith
authors.affiliation: Cleveland Clinic, Cleveland, OH, USA. E-mail: gonzalez.alexei@gmail.com.
authors.forename: A
authors.initials: A
authors.lastname: Gonzalez-Estrada
authors.affiliation: Cleveland Clinic, Cleveland, OH, USA.
authors.forename: J
authors.initials: J
authors.lastname: Fernandez
authors.affiliation: Cleveland Clinic, Cleveland, OH, USA.
authors.forename: A
authors.initials: A
authors.lastname: Subramanian
mesh_terms: D003888:Desensitization, Immunologic / Q000379:methods*; D004342:Drug Hypersensitivity / Q000175:diagnosis / Q000276:immunology / Q000628:therapy*; D005260:Female; D006084:Graft Rejection / Q000276:immunology / Q000517:prevention & control; D006085:Graft Survival / Q000187:drug effects; D016027:Heart Transplantation / Q000009:adverse effects; D006801:Humans; D007166:Immunosuppressive Agents / Q000008:administration & dosage* / Q000276:immunology; D016030:Kidney Transplantation / Q000009:adverse effects; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000009:adverse effects* / Q000276:immunology; D013997:Time Factors; D016896:Treatment Outcome
chemical_list: D007166:Immunosuppressive Agents; D009173:Mycophenolic Acid
keywords: IgE reactions; adverse drug reaction; desensitization