title: Rapid simultaneous analysis of 17 haloacetic acids and related halogenated water contaminants by high-performance ion chromatography-tandem mass spectrometry.
abstract: Haloacetic acids (HAAs), which include chloroacetic acids, bromoacetic acids, and emerging iodoacetic acids, are toxic water disinfection byproducts. General screening methodology is lacking for simultaneously monitoring chloro-, bromo-, and iodoacetic acids. In this study, a rapid and sensitive high-performance ion chromatography-tandem mass spectrometry method for simultaneous determination of chloro-, bromo-, and iodo- acetic acids and related halogenated contaminants including bromate, bromide, iodate, and iodide was developed to directly analyze water samples after filtration, eliminating the need for preconcentration, and chemical derivatization. The resulting method was validated in both untreated and treated water matrices including tap water, bottled water, swimming pool water, and both source water and drinking water from a drinking water treatment facility to demonstrate application potential. Satisfactory accuracies and precisions were obtained for all types of tested samples. The detection limits of this newly developed method were lower or comparable with similar techniques without the need for extensive sample treatment requirement and it includes all HAAs and other halogenated compounds. This provides a powerful methodology to water facilities for routine water quality monitoring and related water research, especially for the emerging iodoacetic acids. Graphical abstract High performance ion chromatography-tandem mass spectrometry method for detection of haloacetic acids in water.
authors.affiliation: Department of Chemistry and Environmental Research Center, Missouri University of Science and Technology, Rolla, MO, 65409, USA.|Center for Single Nanoparticle, Single Cell, and Single Molecule Monitoring (CS3M), Missouri University of Science and Technology, Rolla, MO, 65409, USA.
authors.forename: Runmiao
authors.initials: R
authors.lastname: Xue
authors.affiliation: Department of Chemistry and Environmental Research Center, Missouri University of Science and Technology, Rolla, MO, 65409, USA.|Center for Single Nanoparticle, Single Cell, and Single Molecule Monitoring (CS3M), Missouri University of Science and Technology, Rolla, MO, 65409, USA.
authors.forename: Ariel
authors.initials: A
authors.lastname: Donovan
authors.affiliation: Department of Chemistry and Environmental Research Center, Missouri University of Science and Technology, Rolla, MO, 65409, USA. honglan@mst.edu.|Center for Single Nanoparticle, Single Cell, and Single Molecule Monitoring (CS3M), Missouri University of Science and Technology, Rolla, MO, 65409, USA. honglan@mst.edu.
authors.forename: Honglan
authors.initials: H
authors.lastname: Shi
authors.affiliation: Department of Agriculture and Environmental Sciences, Lincoln University of Missouri, Jefferson City, MO, 65101, USA.
authors.forename: John
authors.initials: J
authors.lastname: Yang
authors.affiliation: Department of Agriculture and Environmental Sciences, Lincoln University of Missouri, Jefferson City, MO, 65101, USA.
authors.forename: Bin
authors.initials: B
authors.lastname: Hua
authors.affiliation: Department of Civil and Environmental Engineering, University of Missouri-Columbia, Columbia, MO, 65211, USA.
authors.forename: Enos
authors.initials: E
authors.lastname: Inniss
authors.affiliation: Missouri Department of Natural Resources, Jefferson City, MO, 65102, USA.
authors.forename: Todd
authors.initials: T
authors.lastname: Eichholz
keywords: Bromate; Haloacetic acids; High-performance ion chromatography-mass spectrometry; Iodoacetic acid; Water disinfection byproducts