title: Myocardial Perfusion SPECT Imaging in Dextrocardia with Situs Inversus: A Case Report.
abstract: Dextrocardia is a cardiac positional anomaly in which the heart is located in the right hemithorax with its base-to-apex axis directed to the right and caudad. Situs inversus is an autosomal recessive disorder that causes organs in the chest and abdomen to be positioned in a mirror image from their normal position. Dextrocardia may occur in isolation or as part of situs inversus. Similarly, situs inversus may occur with or without dextrocardia. Situs inversus accompanied with dextrocardia (situs inversus totalis) is a rare congenital abnormality occurring in 0.01% of live births. Herein, we present the case of a 35-year-old man with previously diagnosed situs inversus totalis with mirror-image dextrocardia, referred to our facility for diagnosis of coronary artery disease (CAD). The incidence and presentation of CAD in patients with dextrocardia are similar to the normal population. However, considerable attention should be paid to the acquisition of myocardial perfusion scintigraphy and data processing/analysis in this group of patients. The present case highlights the distinctive applications and potential pitfalls of myocardial perfusion single-photon emission computed tomography (SPECT) imaging in patients with dextrocardia.
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiation Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa.
authors.forename: Olusegun Akinwale
authors.initials: OA
authors.lastname: Ayeni
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiation Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa.
authors.forename: Nico
authors.initials: N
authors.lastname: Malan
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiation Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa.
authors.forename: Emmanuel Niiboye
authors.initials: EN
authors.lastname: Hammond
authors.affiliation: Division of Nuclear Medicine and Molecular Imaging, Department of Radiation Sciences, University of the Witwatersrand, Charlotte Maxeke Johannesburg Academic Hospital, Johannesburg, South Africa.
authors.forename: Mboyo-Di-Tamba Heben
authors.initials: MD
authors.lastname: Vangu
keywords: Dextrocardia; Image processing; Myocardial perfusion imaging; Situs inversus totalis