title: [INFLUENCE OF ANGIOPROTECTOR DRUGS ON THE EFFICACY OF CYTOSTATIC THERAPY (EXPERIMENTAL STUDY)].
abstract: The influence of angioprotector and endothelium-protector drugs pentoxifylline and unifuzol as components of supportive therapy on the efficacy of combined cytostatic treatment has been experimentally studied. It is established that pentoxifylline and unifuzol do not affect the antitumor and antimetastatic activity of doxorubicin and cyclophosphan with respect to Pliss lymphosarcoma and Walker 256 carcinosarcoma, and in some cases even potentiate the effect of cytostatic therapy.
authors.forename: A P
authors.initials: AP
authors.lastname: Trashkov
authors.forename: A G
authors.initials: AG
authors.lastname: Vasil'ev
authors.forename: A L
authors.initials: AL
authors.lastname: Kovalenko
authors.forename: A Yu
authors.initials: AY
authors.lastname: Petrov
authors.forename: V V
authors.initials: VV
authors.lastname: Valeev
mesh_terms: D020533:Angiogenesis Inhibitors / Q000494:pharmacology*; D000818:Animals; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000494:pharmacology*; D001125:Argininosuccinic Acid / Q000494:pharmacology*; D002279:Carcinoma 256, Walker / Q000188:drug therapy* / Q000473:pathology; D049109:Cell Proliferation / Q000187:drug effects; D003520:Cyclophosphamide / Q000494:pharmacology; D054697:Cytostatic Agents / Q000494:pharmacology*; D004317:Doxorubicin / Q000494:pharmacology; D004357:Drug Synergism; D008228:Lymphoma, Non-Hodgkin / Q000188:drug therapy* / Q000473:pathology; D008297:Male; D010431:Pentoxifylline / Q000494:pharmacology*; D051381:Rats; D017208:Rats, Wistar; D047368:Tumor Burden / Q000187:drug effects; D023041:Xenograft Model Antitumor Assays
chemical_list: D020533:Angiogenesis Inhibitors; D054697:Cytostatic Agents; D001125:Argininosuccinic Acid; D004317:Doxorubicin; D003520:Cyclophosphamide; D010431:Pentoxifylline