title: A case report of a woman with young onset cognitive impairment associated with hereditary spastic paraplegia due to a mutation in the SPAST gene.
authors.affiliation: Yale Department of Neurology, 800 Howard Avenue, New Haven, CT 06511, United States. Electronic address: annya.tisher@gmail.com.
authors.forename: Annya
authors.initials: A
authors.lastname: Tisher
authors.affiliation: Yale Department of Neurology, 800 Howard Avenue, New Haven, CT 06511, United States. Electronic address: arash.salardini@yale.edu.
authors.forename: Arash
authors.initials: A
authors.lastname: Salardini
mesh_terms: D000251:Adenosine Triphosphatases / Q000235:genetics*; D000328:Adult; D001921:Brain / Q000000981:diagnostic imaging; D060825:Cognitive Dysfunction / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics* / Q000503:physiopathology; D005260:Female; D006801:Humans; D009154:Mutation; D010375:Pedigree; D015419:Spastic Paraplegia, Hereditary / Q000150:complications* / Q000000981:diagnostic imaging / Q000235:genetics* / Q000503:physiopathology; D000074181:Spastin
chemical_list: D000251:Adenosine Triphosphatases; D000074181:Spastin; C400283:SPAST protein, human
keywords: Cognitive impairment; Dementia; Hereditary spastic paraplegia; SPAST; SPG4; Spastin