title: Maternal Near Miss According to World Health Organization Classification Among Women with a Hydatidiform Mole: Experience at the New England Trophoblastic Disease Center, 1994-2013.
abstract: OBJECTIVE
  To investigate the frequency of potentially life-threatening conditions (PLTCs) and maternal near misses (MNMs) at the New England Trophoblastic Disease Center (NETDC) in recent years, when there has been earlier diagnosis of molar pregnancy.
  
  
  METHODS
  This study included patients with molar pregnancy at the NETDC between 1994 and 2013. Clinical and pathologic reports were reviewed. PLTC and MNM criteria and maternal deaths were searched in medical records using the World Health Organization criteria and classification.
  
  
  RESULTS
  We identified 375 patients with molar pregnancy and no patient developed a MNM or maternal death. Only 6 (1.6%) had PLTCs (hemorrhage with hemodynamic instability, severe preeclampsia, respiratory distress, blood transfusion, and ICU admission).
  
  
  CONCLUSIONS
  We observed a low rate of PLTC and no cases of MNMs or maternal deaths related to molar pregnancy, likely due to earlier diagnosis at the NETDC in recent years.
authors.forename: Sue Yazaki
authors.initials: SY
authors.lastname: Sun
authors.forename: Donald P
authors.initials: DP
authors.lastname: Goldstein
authors.forename: Marilyn R
authors.initials: MR
authors.lastname: Bernstein
authors.forename: Neil S
authors.initials: NS
authors.lastname: Horowitz
authors.forename: Rosiane
authors.initials: R
authors.lastname: Mattar
authors.forename: Izildinha
authors.initials: I
authors.lastname: Maestá
authors.forename: Antonio
authors.initials: A
authors.lastname: Braga
authors.forename: Ross S
authors.initials: RS
authors.lastname: Berkowitz
mesh_terms: D000293:Adolescent; D000328:Adult; D001803:Blood Transfusion / Q000706:statistics & numerical data; D005260:Female; D031901:Gestational Trophoblastic Disease / Q000453:epidemiology / Q000401:mortality; D006801:Humans; D006828:Hydatidiform Mole / Q000453:epidemiology* / Q000401:mortality; D007362:Intensive Care Units / Q000706:statistics & numerical data; D063130:Maternal Death / Q000706:statistics & numerical data*; D000067491:Near Miss, Healthcare / Q000706:statistics & numerical data*; D009511:New England; D011225:Pre-Eclampsia / Q000453:epidemiology*; D011247:Pregnancy; D012128:Respiratory Distress Syndrome / Q000453:epidemiology; D012189:Retrospective Studies; D014592:Uterine Hemorrhage / Q000453:epidemiology*; D014594:Uterine Neoplasms / Q000453:epidemiology* / Q000401:mortality; D014944:World Health Organization; D055815:Young Adult