title: [Langerhans cell histiocytosis with vertebral involvement and soft tissue extension: clinical case].
abstract: Langerhans cell histiocytosis is a heterogeneous disease of unknown etiology characterized by proliferation of Langerhans cells. It is a rare disease. Bone involvement is common but vertebral disease is rare. We present a 4 year old patient with abdominal pain and neurologic symptoms. Magnetic resonance showed vertebra plana in D9 with involvement of paravertebral soft tissues. The child underwent surgery for decompression and biopsy. Biopsy confirmed Langerhans cell histiocytosis. She was treated with vinblastine and prednisone during 6 months following LCH-III with complete recovery of neurologic symptoms.
  
  
  CONCLUSIONS
  Langerhans cell histiocytosis is a differential diagnosis in a radiograph with vertebra plana or collapse of vertebral body.
authors.affiliation: Servicio de Clínica Médica, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Tai C
authors.initials: TC
authors.lastname: Luong
authors.affiliation: Servicio de Clínica Médica, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina. ascrigni@intramed.net.
authors.forename: Adriana
authors.initials: A
authors.lastname: Scrigni
authors.affiliation: Servicio de Clínica Médica, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Marcela
authors.initials: M
authors.lastname: Paglia
authors.affiliation: Servicio de Clínica Médica, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Mariano
authors.initials: M
authors.lastname: Garavaglia
authors.affiliation: Servicio de Clínica Médica, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Nuria
authors.initials: N
authors.lastname: Aisenberg
authors.affiliation: Servicio de Clínica Médica, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Hernán
authors.initials: H
authors.lastname: Rowensztein
authors.affiliation: Servicio de Hematooncología, Hospital de Pediatría Juan P. Garrahan, Ciudad Autónoma de Buenos Aires, Argentina.
authors.forename: Claudia
authors.initials: C
authors.lastname: Sampor
mesh_terms: D001415:Back; D002675:Child, Preschool; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications*; D006801:Humans; D013122:Spinal Diseases / Q000209:etiology*; D013904:Thoracic Vertebrae
keywords: Langerhans cell histiocytosis; Spinal diseases; Vertebra plana