title: A rare case of clinically and biochemically silent giant right pheochromocytoma: case report and review of literature.
abstract: Non-secreting pheochromocytomas are rare adrenal tumours. We report the case of a clinically and biochemically silent giant pheochromocytoma that presented as bilateral pulmonary embolisms. Successful surgical resection was performed. Multiple endocrine neoplasia 2 syndrome and neurofibromatosis type 1 were clinically excluded. Subsequent DNA analysis of the succinate dehydrogenase complex subunits B and D (SDHB and SDHD), and Von Hippel-Lindau (VHL) genes revealed no mutations.
authors.affiliation: a Ghent University , Gent , Belgium.
authors.forename: Nora
authors.initials: N
authors.lastname: Sundahl
authors.affiliation: b Department of Head and Neck Surgery , UZ Ghent , Ghent , Belgium.|c Department of General and Endocrine Surgery , OLV Clinic Aalst , Aalst , Belgium.
authors.forename: Sam
authors.initials: S
authors.lastname: Van Slycke
authors.affiliation: d Upper Gastrointestinal Surgery, Department of Molecular Medicine and Surgery , Karolinska Institutet , Stockholm , Sweden.
authors.forename: Nele
authors.initials: N
authors.lastname: Brusselaers
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000175:diagnosis* / Q000601:surgery*; D000315:Adrenalectomy / Q000379:methods*; D002395:Catecholamines / Q000097:blood / Q000652:urine; D004636:Emergency Service, Hospital; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D010673:Pheochromocytoma / Q000175:diagnosis* / Q000601:surgery*; D049268:Positron-Emission Tomography / Q000379:methods; D035583:Rare Diseases; D018570:Risk Assessment; D012720:Severity of Illness Index; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome
chemical_list: D002395:Catecholamines
keywords: Adrenal gland neoplasms; case report; pulmonary embolism