title: Inverse focusing inside turbid media by creating an opposite virtual objective.
abstract: Limited by the penetration depth, imaging of thick bio-tissues can be achieved only by epi-detection geometry. Applications based on forward-emitted signals or bidirectional illumination are restricted by lack of an opposite objective. A method for creating an opposite virtual objective inside thick media through phase conjugation was first proposed. Under forward illumination, the backward scattering light from the media was collected to generate a phase conjugate wave, which was sent back to the media and formed an inverse focusing light. Samples combined with a diffuser or a mouse skin were used as specimens. Inverse focusing was successfully demonstrated by applying holography-based optical phase conjugation with a BaTiO3. This result indicates the capability to create an opposite virtual objective inside live tissues. The proposed method is compatible with current coherent imaging and super-resolution imaging technologies. It creates a possible way for forward-emitted signals collection and bidirectional illumination in thick specimens.
authors.affiliation: Department of Optics and Photonics, National Central University, Chung-Li, Taoyuan City, 32001 Taiwan.|Optical Science Center, National Central University, Chung-Li, Taoyuan City, 32001 Taiwan.
authors.forename: Yeh-Wei
authors.initials: YW
authors.lastname: Yu
authors.affiliation: Department of Optics and Photonics, National Central University, Chung-Li, Taoyuan City, 32001 Taiwan.
authors.forename: Szu-Yu
authors.initials: SY
authors.lastname: Chen
authors.affiliation: Department of Optics and Photonics, National Central University, Chung-Li, Taoyuan City, 32001 Taiwan.
authors.forename: Che-Chu
authors.initials: CC
authors.lastname: Lin
authors.affiliation: Department of Optics and Photonics, National Central University, Chung-Li, Taoyuan City, 32001 Taiwan.
authors.forename: Ching-Cherng
authors.initials: CC
authors.lastname: Sun