title: WHICH AIRWAY PRESSURE SHOULD BE APPLIED DURING BREATH-HOLD IN DOGS UNDERGOING THORACIC COMPUTED TOMOGRAPHY?
abstract: This randomized controlled trial study aimed to identify the optimal positive pressure (PP) level that can clear atelectasis while avoiding pulmonary hyperinflation during the breath-hold technique in dogs undergoing thoracic computed tomography (CT). Sixty dogs affected by mammary tumors undergoing thoracic CT for the screening of pulmonary metastases were randomly assigned to six groups with different levels of PP during the breath-hold technique: 0 (control), 5 (PP5), 8 (PP8), 10 (PP10), 12 (PP12), and 15 (PP15) cmH2 O. The percentage of atelectatic lung region was lower in the PP10 (3.7 ± 1.1%; P = 0.002), PP12 (3.4 ± 1.3%; P = 0.0001), and PP15 (2.8 ± 0.9%; P = 0.006) groups than in the control group (5.0 ± 2.3%), and the percentage of poorly aerated lung region was lower in the PP8 (15.1 ± 2.6%; P = 0.0009), PP10 (13.0 ± 2.0 %; P = 0.002), PP12 (13.0 ± 2.2 %; P = 0.0002), and PP15 (11.1 ± 1.9%; P = 0.0002) groups than in the control group (19.8 ± 5.0). The percentage of normally aerated lung region, however, was higher in the PP10 (79.7 ± 4.1%; P = 0.005), PP12 (79.8 ± 5.1%; P = 0.0002), and PP15 (80.2 ± 4.9%; P = 0.002) groups than in the control group (73.4 ± 6.6%). A PP of 10-12 cmH2 O during the breath-hold technique should be considered to improve lung aeration during a breath-hold technique in dogs undergoing thoracic CT.
authors.affiliation:  Dipartimento delle Emergenze e Trapianti di Organo, Università degli Studi di Bari "Aldo Moro," sezione Cliniche Veterinarie e P.A, Valenzano.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Guarracino
authors.affiliation:  Dipartimento delle Emergenze e Trapianti di Organo, Università degli Studi di Bari "Aldo Moro," sezione Cliniche Veterinarie e P.A, Valenzano.
authors.forename: Luca
authors.initials: L
authors.lastname: Lacitignola
authors.affiliation: Istituto Veterinario di Novara.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Auriemma
authors.affiliation: Dipartimento di Medicina Veterinaria, Università di Perugia, Perugia.
authors.forename: Valentina
authors.initials: V
authors.lastname: De Monte
authors.affiliation: Dipartimento dell'Emergenza e dei Trapianti d'Organo, Università degli Studi di Bari "Aldo Moro", Sezione di Anestesia e Rianimazione.
authors.forename: Salvatore
authors.initials: S
authors.lastname: Grasso
authors.affiliation:  Dipartimento delle Emergenze e Trapianti di Organo, Università degli Studi di Bari "Aldo Moro," sezione Cliniche Veterinarie e P.A, Valenzano.
authors.forename: Antonio
authors.initials: A
authors.lastname: Crovace
authors.affiliation:  Dipartimento delle Emergenze e Trapianti di Organo, Università degli Studi di Bari "Aldo Moro," sezione Cliniche Veterinarie e P.A, Valenzano. francesco.staffieri@uniba.it.
authors.forename: Francesco
authors.initials: F
authors.lastname: Staffieri
mesh_terms: D000818:Animals; D004283:Dog Diseases / Q000000981:diagnostic imaging*; D004285:Dogs; D005260:Female; D015674:Mammary Neoplasms, Animal / Q000000981:diagnostic imaging* / Q000209:etiology; D001261:Pulmonary Atelectasis / Q000000981:diagnostic imaging / Q000517:prevention & control / Q000662:veterinary*; D014057:Tomography, X-Ray Computed / Q000379:methods / Q000662:veterinary*
keywords: atelectasis; breath-hold; computed tomography; dogs; positive pressure