title: Effects of Low-Flow Sevoflurane Anesthesia on Pulmonary Functions in Patients Undergoing Laparoscopic Abdominal Surgery.
abstract: Objective. The aim of this prospective, randomized study was to investigate the effects of low-flow sevoflurane anesthesia on the pulmonary functions in patients undergoing laparoscopic cholecystectomy. Methods. Sixty American Society of Anesthesiologists (ASA) physical status classes I and II patients scheduled for elective laparoscopic cholecystectomy were included in the study. Patients were randomly allocated to two study groups: high-flow sevoflurane anesthesia group (Group H, n = 30) and low-flow sevoflurane anesthesia group (Group L, n = 30). The fresh gas flow rate was of 4 L/min in high-flow sevoflurane anesthesia group and 1 L/min in low-flow sevoflurane anesthesia group. Heart rate (HR), mean arterial blood pressure (MABP), peripheral oxygen saturation (SpO2), and end-tidal carbon dioxide concentration (ETCO2) were recorded. Pulmonary function tests were performed before and 2, 8, and 24 hours after surgery. Results. There was no significant difference between the two groups in terms of HR, MABP, SpO2, and ETCO2. Pulmonary function test results were similar in both groups at all measurement times. Conclusions. The effects of low-flow sevoflurane anesthesia on pulmonary functions are comparable to high-flow sevoflurane anesthesia in patients undergoing laparoscopic cholecystectomy.
authors.affiliation: Department of Anesthesiology and Reanimation, Ankara Ataturk Training and Research Hospital, 06800 Ankara, Turkey.
authors.forename: Cihan
authors.initials: C
authors.lastname: Doger
authors.affiliation: Department of Anesthesiology and Reanimation, Ulus State Hospital, 06050 Ankara, Turkey.
authors.forename: Kadriye
authors.initials: K
authors.lastname: Kahveci
authors.affiliation: Department of Anesthesiology and Reanimation, Ankara Numune Training and Research Hospital, 06230 Ankara, Turkey.
authors.forename: Dilsen
authors.initials: D
authors.lastname: Ornek
authors.affiliation: Department of Anesthesiology and Reanimation, Faculty of Medicine, Yildirim Beyazit University, 06800 Ankara, Turkey.
authors.forename: Abdulkadir
authors.initials: A
authors.lastname: But
authors.affiliation: Department of Anesthesiology and Reanimation, Faculty of Medicine, Yildirim Beyazit University, 06800 Ankara, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Aksoy
authors.affiliation: Department of Anesthesiology and Reanimation, Ulus State Hospital, 06050 Ankara, Turkey.
authors.forename: Derya
authors.initials: D
authors.lastname: Gokcinar
authors.affiliation: Department of Pulmonology, Ankara Yenimahalle State Hospital, 06370 Ankara, Turkey.
authors.forename: Didem
authors.initials: D
authors.lastname: Katar
mesh_terms: D000005:Abdomen / Q000503:physiopathology / Q000601:surgery*; D000328:Adult; D000758:Anesthesia / Q000379:methods*; D062186:Arterial Pressure / Q000187:drug effects; D002245:Carbon Dioxide / Q000032:analysis; D002763:Cholecystectomy / Q000379:methods; D005260:Female; D006339:Heart Rate; D006801:Humans; D010535:Laparoscopy / Q000379:methods*; D008168:Lung / Q000187:drug effects / Q000502:physiology; D008297:Male; D008738:Methyl Ethers / Q000008:administration & dosage*; D008875:Middle Aged; D009609:Nitrous Oxide / Q000008:administration & dosage; D012129:Respiratory Function Tests; D000077149:Sevoflurane
chemical_list: D008738:Methyl Ethers; D002245:Carbon Dioxide; D000077149:Sevoflurane; D009609:Nitrous Oxide