title: Heterocycle FormationviaPalladium-Catalyzed C-H Functionalization.
abstract: Heterocyclic compounds are ubiquitous in natural products, pharmaceuticals, and agrochemicals. Therefore, the design of novel protocols to construct heterocycles more efficiently is a major area of focus in the organic chemistry. In the past several years, cyclization reactions based upon palladium-catalyzed C-H activation have received substantial attention due to their capacity for expediting heterocycle synthesis. This review discusses strategies for heterocycle synthesisviapalladium-catalyzed C-H bond activation and highlights recent examples from the literature.
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037 (USA).
authors.forename: Tian-Sheng
authors.initials: TS
authors.lastname: Mei
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037 (USA).
authors.forename: Lei
authors.initials: L
authors.lastname: Kou
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037 (USA).
authors.forename: Sandy
authors.initials: S
authors.lastname: Ma
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037 (USA).
authors.forename: Keary M
authors.initials: KM
authors.lastname: Engle
authors.affiliation: Department of Chemistry, The Scripps Research Institute, 10550 North Torrey Pines Rd., La Jolla, CA 92037 (USA).
authors.forename: Jin-Quan
authors.initials: JQ
authors.lastname: Yu
keywords: C–H activation; Heterocycle; amination; carbonylation; olefination