title: Recurrent "pneumonia" in left lower lobe lasting for 8 years: a case report.
abstract: Bronchioloalveolar carcinoma (BAC) is a unique lung neoplasm with variable forms, such as single nodular, multifocal and lobar pneumonic types. The pneumonic type BAC is often difficult to differentiate from pneumonia. Here we present a case of 63-year-old Chinese male, who had recurrent cough, white sputum with pneumonic lesions in left lower lobe. He suffered from lung biopsies for three times, and finally diagnosed as high differentiated adenocarcinoma 8 years later. He was treated with four cycles of pemetrexed and cisplatin, and four cycles of docetaxel and nedaplatin. However, he did not achieve disease stabilization and is still under follow up. This case suggests that, pneumonic type adenocarcinoma may radiographically and clinically resemble infectious pneumonia. Lack of fever and leukocytosis, no response to antibiotics, air bronchogram, and accompanied nodules or patches in computed tomography (CT) scans should raise suspicion about the diagnosis of pneumonia. Lung biopsy might be the only means of ruling in a diagnosis of BAC.
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Dong-Mei
authors.initials: DM
authors.lastname: Yuan
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Yan-Wen
authors.initials: YW
authors.lastname: Yao
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Li
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Chen-Yang
authors.initials: CY
authors.lastname: Liu
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Pei
authors.initials: P
authors.lastname: Li
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: E-Hong
authors.initials: EH
authors.lastname: Cao
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Xin-Wu
authors.initials: XW
authors.lastname: Xiao
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Su
authors.affiliation: 1 Department of Respiratory Medicine, Jinling Hospital, Nanjing University School of Medicine, Nanjing 210002, China ; 2 Department of Respiratory Medicine, Jinling Hospital, Southern Medical University, Nanjing 210002, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Song
keywords: Pneumonic-type adenocarcinoma (P-ADCs); bronchioloalveolar carcinoma (BAC); lung biopsy