title: Beard infantile hemangioma and subglottic involvement: are median pattern and telangiectatic aspect the clue?
abstract: BACKGROUND
  Identification of patient at risk of subglottic infantile hemangioma (IH) is challenging because subglottic IH can grow fast and cause airway obstruction with a fatal course.
  
  
  OBJECTIVE
  To refine the cutaneous IH pattern at risk of subglottic IH.
  
  
  METHODS
  Prospective and retrospective review of patients with cutaneous IH involving the beard area. IHs were classified in the bilateral pattern group (BH) or in the unilateral pattern group (UH). Infantile hemangioma topography, subtype (telangiectatic or tuberous), ear, nose and throat (ENT) manifestations and subglottic involvement were recorded.
  
  
  RESULTS
  Thirty-one patients (21 BH and 10 UH) were included during a 20-year span. Nineteen patients (16 BH and 3 UH) had subglottic hemangioma. BH and UH group overlap on the median pattern (tongue, gum, lips, chin and neck). Median pattern, particularly the neck area and telangiectatic subtype of IH were significantly associated with subglottic involvement.
  
  
  CONCLUSIONS
  Patients presenting with telangiectatic beard IH localized on the median area need early ENT exploration. They should be treated before respiratory symptoms occur.
authors.affiliation: Reference center for genodermatoses and rare skin diseases (MAGEC), Department of Dermatology, Hôpital Necker-Enfants Malades, AP-HP, Paris, France.|Department of Pediatric Rheumatology, Hôpital de Bicêtre, AP-HP, Le Kremlin-Bicêtre, France.|University of Paris Sud, Le Kremlin-Bicêtre, France.
authors.forename: M
authors.initials: M
authors.lastname: Piram
authors.affiliation: Reference center for genodermatoses and rare skin diseases (MAGEC), Department of Dermatology, Hôpital Necker-Enfants Malades, AP-HP, Paris, France.|University of Paris Descartes - Sorbonne Paris Cité, Institut Imagine, Paris, France.
authors.forename: S
authors.initials: S
authors.lastname: Hadj-Rabia
authors.affiliation: Reference center for genodermatoses and rare skin diseases (MAGEC), Department of Dermatology, Hôpital Necker-Enfants Malades, AP-HP, Paris, France.
authors.forename: O
authors.initials: O
authors.lastname: Boccara
authors.affiliation: University of Paris Descartes - Sorbonne Paris Cité, Institut Imagine, Paris, France.|Department of Otorhinolaryngology, Hôpital Necker Enfants-Malades, AP-HP, Paris, France.
authors.forename: V
authors.initials: V
authors.lastname: Couloigner
authors.affiliation: Reference center for genodermatoses and rare skin diseases (MAGEC), Department of Dermatology, Hôpital Necker-Enfants Malades, AP-HP, Paris, France.
authors.forename: D
authors.initials: D
authors.lastname: Hamel-Teillac
authors.affiliation: Reference center for genodermatoses and rare skin diseases (MAGEC), Department of Dermatology, Hôpital Necker-Enfants Malades, AP-HP, Paris, France.|University of Paris Descartes - Sorbonne Paris Cité, Institut Imagine, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Bodemer
mesh_terms: D002675:Child, Preschool; D005260:Female; D005931:Glottis / Q000473:pathology*; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male; D011446:Prospective Studies; D012189:Retrospective Studies; D013684:Telangiectasis / Q000473:pathology*