title: Dynamic and diverse sugar signaling.
abstract: Sugars fuel life and exert numerous regulatory actions that are fundamental to all life forms. There are two principal mechanisms underlie sugar 'perception and signal transduction' in biological systems. Direct sensing and signaling is triggered via sugar-binding sensors with a broad range of affinity and specificity, whereas sugar-derived bioenergetic molecules and metabolites modulate signaling proteins and indirectly relay sugar signals. This review discusses the emerging sugar signals and potential sugar sensors discovered in plant systems. The findings leading to informative understanding of physiological regulation by sugars are considered and assessed. Comparative transcriptome analyses highlight the primary and dynamic sugar responses and reveal the convergent and specific regulators of key biological processes in the sugar-signaling network.
authors.affiliation: Department of Genetics, Harvard Medical School, USA; Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, MA 02114, USA.
authors.forename: Lei
authors.initials: L
authors.lastname: Li
authors.affiliation: Department of Genetics, Harvard Medical School, USA; Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, MA 02114, USA. Electronic address: sheen@molbio.mgh.harvard.edu.
authors.forename: Jen
authors.initials: J
authors.lastname: Sheen
mesh_terms: D017360:Arabidopsis / Q000502:physiology*; D050260:Carbohydrate Metabolism; D018506:Gene Expression Regulation, Plant; D010940:Plant Proteins / Q000235:genetics* / Q000378:metabolism; D015398:Signal Transduction; D059467:Transcriptome
chemical_list: D010940:Plant Proteins