title: [Diagnosis and follow-up observation of granulosa cell tumor of the ovary are becoming more precise].
abstract: Granulosa cell tumor of the ovary is a rare, hormonally active ovarian cancer, typical symptoms of which include various gynecological bleeding disorders. Adult granulosa cell tumor is most commonly detected at stage I, whereupon the prognosis is good. The disease, however, recurs in one third of stage I patients and leads to death in half of these. Conventional cytotoxic agents may be ineffective in the treatment of relapsed tumors. Inhibin B and anti-Müllerian hormone have proven to be sensitive and accurate markers. Knowledge about the disease mechanisms has improved the diagnostics and follow-up observation of the patients.
authors.forename: Anniina
authors.initials: A
authors.lastname: Färkkilä
authors.forename: Leila
authors.initials: L
authors.lastname: Unkila-Kallio
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D005260:Female; D006106:Granulosa Cell Tumor / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D006801:Humans; D009364:Neoplasm Recurrence, Local; D009367:Neoplasm Staging; D019370:Observation; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000628:therapy*; D011379:Prognosis
chemical_list: D014408:Biomarkers, Tumor