title: Bowel perforation from occult ileal involvement after diagnosis in a case of primary mediastinal large B-cell lymphoma.
abstract: Primary mediastinal large B-cell lymphoma (PMBCL) is confined to the mediastinum or contiguous nodal areas in most cases. Extramediastinal and abdominal involvement, especially at diagnosis, is extremely rare. Our case describes the first case of histologically proven ileal involvement of PMBCL at diagnosis that led to ileal perforation. Positron emission tomography CT could increase the sensitivity of staging by detecting unusual sites of disease localisation, and could impact clinical management.
authors.affiliation: Department of Oncology and Onco-Hematology, Università degli Studi di Milano, Milano, Italy.
authors.forename: Chiara
authors.initials: C
authors.lastname: De Philippis
authors.affiliation: Department of Oncology and Onco-Hematology, Università degli Studi di Milano, Milano, Italy.
authors.forename: Maria Chiara
authors.initials: MC
authors.lastname: Di Chio
authors.affiliation: Unit of Haemolymphopathology, Department of Haematology & Oncology, S. Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.
authors.forename: Elena
authors.initials: E
authors.lastname: Sabattini
authors.affiliation: Department of Oncology and Onco-Hematology, Università degli Studi di Milano, Milano, Italy.
authors.forename: Niccolo
authors.identifier: http://orcid.org/0000-0002-1018-5139
authors.initials: N
authors.lastname: Bolli
mesh_terms: D000328:Adult; D006801:Humans; D007082:Ileum / Q000000981:diagnostic imaging*; D007416:Intestinal Perforation / Q000000981:diagnostic imaging / Q000209:etiology*; D016403:Lymphoma, Large B-Cell, Diffuse / Q000150:complications* / Q000000981:diagnostic imaging*; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging*; D008482:Mediastinum / Q000000981:diagnostic imaging; D000072078:Positron Emission Tomography Computed Tomography; D014057:Tomography, X-Ray Computed