title: Particulate Matter and Hospital Admissions for Stroke in Beijing, China: Modification Effects by Ambient Temperature.
abstract: The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013-2014.
  
  
  
  A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959-2.190), 1.470 (95% CI 1.391-1.554), and 1.590 (95% CI 1.493-1.694) per IQR increase in the same-day PM2.5 (82.0 μg/m(3)), PM2.5-10 (36.6 μg/m(3)), and PM10 (93.5 μg/m(3)), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658-2.273), 1.590 (95% CI 1.366-1.851), and 1.527 (95% CI 1.278-1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C).
  
  
  
  This study suggests that the associations of PM2.5, PM2.5-10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5-10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Fangfang
authors.initials: F
authors.lastname: Huang
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Yanxia
authors.initials: Y
authors.lastname: Luo
authors.affiliation: School of Public Health, University of Queensland, Brisbane, Australia.
authors.forename: Yuming
authors.initials: Y
authors.lastname: Guo
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Lixin
authors.initials: L
authors.lastname: Tao
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Xu
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Chao
authors.initials: C
authors.lastname: Wang
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Anxin
authors.initials: A
authors.lastname: Wang
authors.affiliation: Graduate Entry Medical School, University of Limerick, Ireland.
authors.forename: Xia
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China.
authors.forename: Jin
authors.initials: J
authors.lastname: Guo
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China Beijing Municipal Science and Technology Commission, Beijing, China statguo@ccmu.edu.cn yanaspublic@126.com.
authors.forename: Aoshuang
authors.initials: A
authors.lastname: Yan
authors.affiliation: School of Public Health, Capital Medical University, Beijing, China Beijing Municipal Key Laboratory of Clinical Epidemiology, Beijing, China statguo@ccmu.edu.cn yanaspublic@126.com.
authors.forename: Xiuhua
authors.initials: X
authors.lastname: Guo
mesh_terms: D000368:Aged; D000397:Air Pollution / Q000009:adverse effects; D000068476:Beijing / Q000453:epidemiology; D005260:Female; D006760:Hospitalization / Q000706:statistics & numerical data*; D006801:Humans; D006813:Humidity; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D052638:Particulate Matter / Q000009:adverse effects*; D020521:Stroke / Q000139:chemically induced* / Q000453:epidemiology; D013696:Temperature
chemical_list: D052638:Particulate Matter
keywords: air pollution; hospital admission; particulate matter; stroke