title: Acute Myocardial Infarction in Sickle Cell Disease: Case Report and Review of the Literature.
abstract: Although vascular occlusion is a hallmark of sickle cell disease, documented myocardial infarction is an uncommon event in these patients. We report a case of an acute lateral myocardial infarction in a 25 year old male homozygous for HbS, who had previously had a relatively benign course of his sickle cell disease. Management of the case included an exchange transfusion and a 6 month period of chronic simple transfusions (2 units packed red cells every 3-4 weeks). We review here the available literature on cardiovascular manifestations of sickle cell disease.
authors.affiliation: a Division of Hematology/Oncology, Department of Medicine , The Toronto Hospital and The University of Toronto.
authors.forename: M
authors.initials: M
authors.lastname: Loutfy
authors.affiliation: a Division of Hematology/Oncology, Department of Medicine , The Toronto Hospital and The University of Toronto.
authors.forename: B
authors.initials: B
authors.lastname: Tyler
authors.affiliation: a Division of Hematology/Oncology, Department of Medicine , The Toronto Hospital and The University of Toronto.
authors.forename: G D
authors.initials: GD
authors.lastname: Sher
keywords: Sickle cell disease; myocardial infarction; vascular occlusion