title: "Bottle Brush Sign"-Spinal Meningeal Disease on 18F-FDG PET-CT Scan.
abstract: A 30-year-old man with a history of stage IV AE diffuse large cell lymphoma of left proximal humerus presented with new onset lower limb weakness at completion of chemotherapy. The F-FDG PET-CT scan showed increased intraspinal uptake from T12 to S1 vertebrae with unique "bottle brush" appearance in keeping with spinal meningeal disease. The leptomeningeal disease was further confirmed on correlative MRI scan.
authors.affiliation: From the Departments of *Nuclear Medicine, and †Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan.
authors.forename: Saima
authors.initials: S
authors.lastname: Riaz
authors.forename: Fozia
authors.initials: F
authors.lastname: Naz
authors.forename: Humayun
authors.initials: H
authors.lastname: Bashir
authors.forename: Imran Khalid
authors.initials: IK
authors.lastname: Niazi
mesh_terms: D000328:Adult; D019788:Fluorodeoxyglucose F18 / Q000493:pharmacokinetics; D006801:Humans; D008223:Lymphoma / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008297:Male; D008577:Meningeal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D019275:Radiopharmaceuticals / Q000493:pharmacokinetics; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000378:metabolism
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18