title: Burden of respiratory disease in Thailand: Results from the APBORD observational study.
abstract: Asia-Pacific Burden of Respiratory Diseases (APBORD) was a cross-sectional, observational study examining the burden of respiratory disease in adults across 6 Asia-Pacific countries.This article reports symptoms, healthcare resource utilization (HCRU), work impairment and cost burden associated with allergic rhinitis (AR), asthma, chronic obstructive pulmonary disease (COPD), and rhinosinusitis in Thailand.Consecutive participants aged ≥18 years with a primary diagnosis of AR, asthma, COPD, or rhinosinusitis were enrolled at 4 hospitals in Thailand during October 2012 and October 2013. Participants completed a survey detailing respiratory symptoms, HCRU, work productivity, and activity impairment. Locally sourced unit costs were used in the calculation of total costs.The study enrolled 1000 patients. The most frequent primary diagnosis was AR (44.2%), followed by rhinosinusitis (24.1%), asthma (23.7%), and COPD (8.0%). Overall, 316 (31.6%) of patients were diagnosed with some combination of the 4 diseases. Blocked nose or congestion (17%) and cough or coughing up phlegm (16%) were the main reasons for the current medical visit. The mean annual cost for patients with a respiratory disease was US$1495 (SD 3133) per patient. Costs associated with work productivity loss were the principal contributor for AR and rhinosinusitis patients while medication costs were the highest contributor for asthma and COPD patients.The study findings highlight the burden associated with 4 prevalent respiratory diseases in Thailand. Thorough investigation of concomitant conditions and improved disease management may help to reduce the burden of these respiratory diseases.
authors.affiliation: Department of Otorhinolaryngology, Faculty of Medicine, Khon Kaen University, Thailand Seoul National University Hospital, Korea National Allergy Asthma Bronchitis Institute, India Institute of Respiratory Medicine, Malaysia Chang Gung Memorial Hospital, Taiwan Chiangmai University Faculty of Medicine Siriraj Hospital, Mahidol University Chulalongkorn University, Thailand Merck & Co., Inc., NJ, USA Optum, Sydney, NSW, Australia National University of Singapore, Singapore.
authors.forename: Sanguansak
authors.initials: S
authors.lastname: Thanaviratananich
authors.forename: Sang-Heon
authors.initials: SH
authors.lastname: Cho
authors.forename: Aloke Gopal
authors.initials: AG
authors.lastname: Ghoshal
authors.forename: Abdul Razak Bin Abdul
authors.initials: ARBA
authors.lastname: Muttalif
authors.forename: Horng-Chyuan
authors.initials: HC
authors.lastname: Lin
authors.forename: Chaicharn
authors.initials: C
authors.lastname: Pothirat
authors.forename: Benjamas
authors.initials: B
authors.lastname: Chuaychoo
authors.forename: Songklot
authors.initials: S
authors.lastname: Aeumjaturapat
authors.forename: Shalini
authors.initials: S
authors.lastname: Bagga
authors.forename: Rab
authors.initials: R
authors.lastname: Faruqi
authors.forename: Shiva
authors.initials: S
authors.lastname: Sajjan
authors.forename: Santwona
authors.initials: S
authors.lastname: Baidya
authors.forename: De Yun
authors.initials: Y
authors.lastname: Wang
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001249:Asthma / Q000453:epidemiology*; D017281:Cost of Illness; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D029424:Pulmonary Disease, Chronic Obstructive / Q000453:epidemiology*; D012220:Rhinitis / Q000453:epidemiology*; D065631:Rhinitis, Allergic / Q000453:epidemiology*; D012852:Sinusitis / Q000453:epidemiology*; D013785:Thailand / Q000453:epidemiology