title: Prognostic clinical factors associated with remission and relapse in bullous pemphigoid.
abstract: BACKGROUND
  Prognostic factors for remission and relapse of bullous pemphigoid (BP) remain uncertain.
  
  
  OBJECTIVE
  To evaluate clinical factors associated with remission and relapse in Korean patients with BP.
  
  
  METHODS
  A retrospective analysis was conducted of 174 patients diagnosed with BP between 1993 and 2014 at Gangnam Severance Hospital in Seoul, Korea.
  
  
  RESULTS
  Of the 174 identified patients, 131 (75.29%) achieved remission after a mean treatment duration of 393.69 days. Prognostic factors for remission were older age (≥70 years) and the absence of an admission history. Of 131 patients who achieved remission, 40 patients (30.53%) experienced relapse after a mean duration of 335.65 days. However, no statistically significant factors were predictive of relapse by multivariate analysis.
  
  
  CONCLUSIONS
  This study suggests BP patients who are older and have no admission history tend to achieve remission.
authors.affiliation: Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: J H
authors.initials: JH
authors.lastname: Lee
authors.affiliation: Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: T H
authors.initials: TH
authors.lastname: Kim
authors.affiliation: Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: S H
authors.initials: SH
authors.lastname: Park
authors.affiliation: Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.|Biostatistics Collaboration Unit, Gangnam Medical Research Center, Yonsei university College of Medicine, Seoul, Korea.
authors.forename: K
authors.initials: K
authors.lastname: Han
authors.affiliation: Department of Dermatology, Gangnam Severance Hospital, Cutaneous Biology Research Institute, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: S-C
authors.initials: SC
authors.lastname: Kim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D010391:Pemphigoid, Bullous / Q000473:pathology*; D011379:Prognosis; D012008:Recurrence; D055815:Young Adult