title: Transoral CO2 Laser Microsurgery Outcomes for Early Glottic Carcinomas T1-T2.
abstract: BACKGROUND
  Transoral laser microsurgery (TLM) has won territory in larynx oncology, establishing itself as an effective option in treatment of glottic, supraglottic, and hypopharynx tumors. Its advantages include limited resections, a reduction in number of tracheostomies, and the use of nasogastric tubes. Moreover, its oncological benefits are similar to those from open surgery in patients with early or advanced stages, when correctly selected.
  
  
  OBJECTIVE
  The objective of this study is to review oncologic outcomes obtained with the treatment of a series of glottic tumors, treated by TLM.
  
  
  METHODS
  Retrospective analysis of patients previously untreated, diagnosed with squamous cell carcinoma of the glottis (T1a, T1b, T2) in a tertiary university hospital. Endpoints for analysis were local control, overall and disease-specific survival, and larynx preservation rate.
  
  
  RESULTS
  The study group included 58 patients that met the inclusion criteria: 57 (98.3%) men and 1 (1.7%) woman. Mean age was 65.5 ± 10.7 years (Min: 46/Max: 88). The tumor stages of the patients included were 30 T1a, 11 (19%) T1b, and 17 (29.3%) T2. Three-year overall survival rate was 89.7% (Fig. 1), and three-year disease-specific survival rate was 96.5%, three-year local control rate was 98.3%, and three-year organ preservation rate was 98.3%.
  
  
  CONCLUSIONS
  TLM is a safe and effective option in the treatment of glottis carcinomas, associated with less morbidity and a high percentage of local control, overall survival, specific survival, and organ preservation.
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Vigo, Vigo, Pontevedra, Spain.
authors.forename: Carlos Miguel
authors.initials: CM
authors.lastname: Chiesa Estomba
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Vigo, Vigo, Pontevedra, Spain.
authors.forename: Frank Alberto Betances
authors.initials: FA
authors.lastname: Reinoso
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Vigo, Vigo, Pontevedra, Spain.
authors.forename: Alejandra Osorio
authors.initials: AO
authors.lastname: Velasquez
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Vigo, Vigo, Pontevedra, Spain.
authors.forename: Jose Luis Rodriguez
authors.initials: JL
authors.lastname: Fernandez
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Vigo, Vigo, Pontevedra, Spain.
authors.forename: Jose Luis Fariña
authors.initials: JL
authors.lastname: Conde
authors.affiliation: Department of Otorhinolaryngology - Head and Neck Surgery, University Hospital of Vigo, Vigo, Pontevedra, Spain.
authors.forename: Carmelo Santidrian
authors.initials: CS
authors.lastname: Hidalgo
keywords: CO2 laser; carcinoma; larynx