title: [Prevalence of metabolic syndrome and associated factors in children and adolescents with obesity].
abstract: BACKGROUND
  The prevalence of overweight and obesity in children in Mexico are high, as well as the complications associated with their presence. The objective of this work was to estimate the prevalence of metabolic syndrome in obese children and adolescents attending a Hospital Clinic and identify the associated factors.
  
  
  METHODS
  Cross sectional design with 120 children and adolescents; of either sex, with exogenous obesity and BMI > 2.0 standard deviations. Personal and family history was collected, blood pressure was measured and determination of serum glucose, insulin, lipoprotein HDL cholesterol and triglycerides were performed. The presence of metabolic syndrome with the ATPIII, WHO and International Diabetes Federation criteria was identified. The association of metabolic syndrome with different variables was identified with chi square test and calculation of odds ratio.
  
  
  RESULTS
  Mean age was 10.6 ± 2.7 years. The prevalence of metabolic syndrome was 37.5% to 54.5% depending on the criteria used. The presence of metabolic syndrome was associated with a history of large birth weight (OR= 2.21 [1.01-4.82]), and insulin resistance (OR= 6.53 [2.40-18.2]).
  
  
  CONCLUSIONS
  The prevalence of metabolic syndrome is high in this group of children and adolescents with obesity. The history of large birth weight and the presence of insulin resistance should alert us to the presence of the disease.
authors.affiliation: Instituto de Nutrición Humana, Departamento de Reproducción Humana Crecimiento y Desarrollo Infantil, Centro Universitario de Ciencias de la Salud de la Universidad de Guadalajara, Guadalajara, Jalisco, México. enrique.romerovelarde@gmail.com.
authors.forename: Enrique
authors.initials: E
authors.lastname: Romero-Velarde
authors.forename: Liuba Marina
authors.initials: LM
authors.lastname: Aguirre-Salas
authors.forename: Yussani Arelhi
authors.initials: YA
authors.lastname: Álvarez-Román
authors.forename: Edgar Manuel
authors.initials: EM
authors.lastname: Vásquez-Garibay
authors.forename: Erika
authors.initials: E
authors.lastname: Casillas-Toral
authors.forename: Salvador
authors.initials: S
authors.lastname: Fonseca-Reyes
mesh_terms: D000293:Adolescent; D002648:Child; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D024821:Metabolic Syndrome / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology*; D008800:Mexico; D063766:Pediatric Obesity / Q000150:complications*; D015995:Prevalence; D012307:Risk Factors
keywords: Children and adolescents; Insulin resistance; Metabolic syndrome X; Obesity