title: Lipid Layers on Polyelectrolyte Multilayers: Understanding Lipid-Polyelectrolyte Interactions and Applications on the Surface Engineering of Nanomaterials.
abstract: In this manuscript we review work of our group on the assembly of lipid layers on top of polyelectrolyte multilayers (PEMs). The assembly of lipid layers with zwitterionic and charged lipids on PEMs is studied as a function of lipid and polyelectrolyte composition by the Quartz Crystal Microbalance. Polyelectrolyte lipid interactions are studied by means of Atomic Force Spectroscopy. We also show the coating of lipid layers for engineering different nanomaterials, i.e., carbon nanotubes and poly(lactic-co-glycolic) nanoparticles and how these can be used to decrease in vitro toxicity and to direct the intracellular localization of nanomaterials.
authors.forename: Eleftheria
authors.initials: E
authors.lastname: Diamanti
authors.forename: Danijela
authors.initials: D
authors.lastname: Gregurec
authors.forename: Romero
authors.initials: R
authors.lastname: Gabriela
authors.forename: J L
authors.initials: JL
authors.lastname: Cuellar
authors.forename: E
authors.initials: E
authors.lastname: Donath
authors.forename: S E
authors.initials: SE
authors.lastname: Moya
mesh_terms: D001692:Biological Transport; D004738:Engineering; D056945:Hep G2 Cells; D006801:Humans; D042541:Intracellular Space / Q000378:metabolism; D019344:Lactic Acid / Q000737:chemistry*; D008051:Lipid Bilayers / Q000737:chemistry* / Q000378:metabolism; D008958:Models, Molecular; D008968:Molecular Conformation; D053758:Nanoparticles / Q000737:chemistry*; D036103:Nanotechnology; D037742:Nanotubes, Carbon / Q000737:chemistry*; D011100:Polyglycolic Acid / Q000737:chemistry*; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D058525:Quartz Crystal Microbalance Techniques; D013499:Surface Properties
chemical_list: D008051:Lipid Bilayers; D037742:Nanotubes, Carbon; D000077182:Polylactic Acid-Polyglycolic Acid Copolymer; D011100:Polyglycolic Acid; D019344:Lactic Acid