title: A rare γ-pyranopyrazole skeleton: design, one-pot synthesis and computational study.
abstract: Drawing upon a consecutive amide coupling and intramolecular cyclisation pathway, a one-pot, straightforward synthetic route has been developed for a range of pyrazole fused γ-pyrone derivatives. The reaction mechanism proposed for the chemoselective formation of γ-pyranopyrazole is furthermore fully supported by experimental and computational studies.
authors.affiliation: Department of Chemistry, Faculty of Science, İzmir Institute of Technology, Urla 35430, Izmir, Turkey. mustafaemrullahoglu@iyte.edu.tr.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Üçüncü
authors.forename: Ceren
authors.initials: C
authors.lastname: Cantürk
authors.forename: Erman
authors.initials: E
authors.lastname: Karakuş
authors.forename: Hüseyin
authors.initials: H
authors.lastname: Zeybek
authors.forename: Uğur
authors.initials: U
authors.lastname: Bozkaya
authors.forename: Emine
authors.initials: E
authors.lastname: Soydaş
authors.forename: Ertan
authors.initials: E
authors.lastname: Şahin
authors.forename: Mustafa
authors.initials: M
authors.lastname: Emrullahoğlu