title: Improving spatial resolution of confocal Raman microscopy by super-resolution image restoration.
abstract: A new super-resolution image restoration confocal Raman microscopy method (SRIR-RAMAN) is proposed for improving the spatial resolution of confocal Raman microscopy. This method can recover the lost high spatial frequency of the confocal Raman microscopy by using Poisson-MAP super-resolution imaging restoration, thereby improving the spatial resolution of confocal Raman microscopy and realizing its super-resolution imaging. Simulation analyses and experimental results indicate that the spatial resolution of SRIR-RAMAN can be improved by 65% to achieve 200 nm with the same confocal Raman microscopy system. This method can provide a new tool for high spatial resolution micro-probe structure detection in physical chemistry, materials science, biomedical science and other areas.
authors.forename: Han
authors.initials: H
authors.lastname: Cui
authors.forename: Weiqian
authors.initials: W
authors.lastname: Zhao
authors.forename: Yun
authors.initials: Y
authors.lastname: Wang
authors.forename: Ying
authors.initials: Y
authors.lastname: Fan
authors.forename: Lirong
authors.initials: L
authors.lastname: Qiu
authors.forename: Ke
authors.initials: K
authors.lastname: Zhu