title: Two new sesquiterpenes from Chloranthus japonicus Sieb.
abstract: Two new sesquiterpenes, namely, 1β,10β-dihydroxy-eremophil-7(11), 8-dien-12,8-olide (1) and 8,12-epoxy-1β-hydroxyeudesm-3,7,11-trien-9-one (2), together with three known sesquiterpenoids, shizukolidol (3), 4α-hydroxy-5α(H)-8β-methoxy-eudesm-7(11)-en-12,8-olide (4), and neolitacumone B (5), and two known monoterpenes, (3R,4S,6R)-p-menth-1-en-3,6-diol (6) and (R)-p-menth-1-en-4,7-diol (7), were isolated from the whole plant of Chloranthus japonicus Sieb. Their structures were elucidated on the basis of spectroscopic data analysis and comparison with those of related known compounds. Compounds 4-7 were isolated from this plant for the first time.
authors.affiliation: a Xi'an Botanical Garden of Shaanxi Province , Institute of Botany of Shaanxi Province , Xi'an , P.R. China.
authors.forename: Qiang-Qiang
authors.initials: QQ
authors.lastname: Lu
authors.affiliation: a Xi'an Botanical Garden of Shaanxi Province , Institute of Botany of Shaanxi Province , Xi'an , P.R. China.
authors.forename: Xin-Wei
authors.initials: XW
authors.lastname: Shi
authors.affiliation: b School of Environmental and Chemical Engineering , Jiangsu University of Science and Technology , Zhenjiang , P.R. China.
authors.forename: Shao-Jun
authors.initials: SJ
authors.lastname: Zheng
authors.affiliation: a Xi'an Botanical Garden of Shaanxi Province , Institute of Botany of Shaanxi Province , Xi'an , P.R. China.
authors.forename: Jun-Hui
authors.initials: JH
authors.lastname: Zhou
authors.affiliation: a Xi'an Botanical Garden of Shaanxi Province , Institute of Botany of Shaanxi Province , Xi'an , P.R. China.
authors.forename: Xin-Ai
authors.initials: XA
authors.lastname: Cui
authors.affiliation: c Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Science , Northwest A&F University , Yangling , P.R. China.
authors.forename: Jin-Ming
authors.initials: JM
authors.lastname: Gao
mesh_terms: D000818:Animals; D001156:Artemia / Q000187:drug effects; D019684:Magnoliopsida / Q000737:chemistry*; D008516:Medicine, Chinese Traditional; D010936:Plant Extracts / Q000032:analysis; D012717:Sesquiterpenes / Q000737:chemistry / Q000302:isolation & purification* / Q000633:toxicity
chemical_list: D010936:Plant Extracts; D012717:Sesquiterpenes; C452829:neolitacumone B
keywords: Chloranthus japonicus; monoterpenes; sesquiterpenes