title: Semax prevents learning and memory inhibition by heavy metals.
abstract: Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly as ascorbic acid or to a comparable degree. These findings confirm the antioxidant properties of Semax.
authors.affiliation: Moscow State University, Moscow, 119992, Russia. a_inozemtsev@mail.ru.
authors.forename: A N
authors.initials: AN
authors.lastname: Inozemtsev
authors.affiliation: Khetagurov North Ossetian State University, Vladikavkaz, North Ossetia, Russia.
authors.forename: S B
authors.initials: SB
authors.lastname: Bokieva
authors.affiliation: Moscow State University, Moscow, 119992, Russia.|Khetagurov North Ossetian State University, Vladikavkaz, North Ossetia, Russia.
authors.forename: O V
authors.initials: OV
authors.lastname: Karpukhina
authors.affiliation: Semenov Institute of Chemical Physics, Russian Academy of Sciences, Moscow, Russia.
authors.forename: K Z
authors.initials: KZ
authors.lastname: Gumargalieva
authors.affiliation: Moscow State University, Moscow, 119992, Russia.
authors.forename: A A
authors.initials: AA
authors.lastname: Kamensky
authors.affiliation: Institute of Molecular Genetics, Russian Academy of Sciences, Moscow, Russia.
authors.forename: N F
authors.initials: NF
authors.lastname: Myasoedov
mesh_terms: D000324:Adrenocorticotropic Hormone / Q000031:analogs & derivatives* / Q000494:pharmacology; D000818:Animals; D000975:Antioxidants / Q000494:pharmacology*; D001362:Avoidance Learning / Q000187:drug effects*; D008297:Male; D008568:Memory / Q000187:drug effects*; D008982:Molybdenum / Q000633:toxicity*; D009942:Organometallic Compounds / Q000633:toxicity*; D010446:Peptide Fragments / Q000494:pharmacology*; D051381:Rats
chemical_list: D000975:Antioxidants; D009942:Organometallic Compounds; D010446:Peptide Fragments; C048487:ACTH (4-7), Pro-Gly-Pro-; D008982:Molybdenum; D000324:Adrenocorticotropic Hormone; C022175:ammonium molybdate; C008261:lead acetate