title: Placental Mechanics in the Zika-Microcephaly Relationship.
abstract: How the Zika virus (ZIKV) accesses the embryo remains unknown. In this issue, Quicke et al. (2016) use an in vitro model of the human placenta to show that placental macrophages are more permissive to ZIKV infection than trophoblasts, which may be refractory to infection (Bayer et al., 2016).
authors.affiliation: Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh, Pittsburgh, PA 15261, USA. Electronic address: adibij@pitt.edu.
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Adibi
authors.affiliation: Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
authors.forename: Yaqi
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: Department of Epidemiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
authors.forename: Abigail R
authors.initials: AR
authors.lastname: Cartus
authors.affiliation: Department of Infectious Diseases and Microbiology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
authors.forename: Phalguni
authors.initials: P
authors.lastname: Gupta
authors.affiliation: Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Developmental Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Computational and Systems Biology, University of Pittsburgh, Pittsburgh, PA 15261, USA.
authors.forename: Lance A
authors.initials: LA
authors.lastname: Davidson
mesh_terms: D000818:Animals; D005260:Female; D006801:Humans; D008322:Mammals; D008831:Microcephaly / Q000821:virology*; D010920:Placenta; D011247:Pregnancy; D000071244:Zika Virus; D000071243:Zika Virus Infection