title: Two new compounds from Melodinus suaveolens.
abstract: Two new compounds, 19-hydroxy-melodinine K (1) and melodiside (2), and 25 known compounds were isolated from leaves and twigs of Melodinus suaveolens. Their structures were elucidated based on 1- and 2-D NMR, FTIR, UV and MS spectroscopic data. 19-hydroxy-melodinine K showed cytotoxic activity against MDA-MB-231 breast, BCG-823 gastric, SW480 colon and Hela cancer cells.
authors.affiliation: a R&D , China Tobacco Yunnan Industrial Co. Ltd , Kunming , China.
authors.forename: Tian Dong
authors.initials: TD
authors.lastname: Zhang
authors.affiliation: a R&D , China Tobacco Yunnan Industrial Co. Ltd , Kunming , China.
authors.forename: Bao Kun
authors.initials: BK
authors.lastname: Zhu
authors.affiliation: a R&D , China Tobacco Yunnan Industrial Co. Ltd , Kunming , China.
authors.forename: Jun
authors.initials: J
authors.lastname: Ling
authors.affiliation: a R&D , China Tobacco Yunnan Industrial Co. Ltd , Kunming , China.
authors.forename: Qian Xu
authors.initials: QX
authors.lastname: Yang
authors.affiliation: b School of Traditional Chinese Medicine, Guangdong Pharmaceutical University , Guangzhou , China.
authors.forename: Xi Feng
authors.initials: XF
authors.lastname: Teng
authors.affiliation: a R&D , China Tobacco Yunnan Industrial Co. Ltd , Kunming , China.
authors.forename: Meng
authors.initials: M
authors.lastname: Wang
mesh_terms: D000972:Antineoplastic Agents, Phytogenic / Q000494:pharmacology; D029062:Apocynaceae / Q000737:chemistry*; D045744:Cell Line, Tumor; D006801:Humans; D009682:Magnetic Resonance Spectroscopy; D018515:Plant Leaves / Q000737:chemistry
chemical_list: D000972:Antineoplastic Agents, Phytogenic
keywords: 19-hydroxy-melodinine K; Melodinus suaveolens; cytotoxicity; melodiside