title: Intraocular Pressure, Tear Production, and Ocular Echobiometry in Guinea Pigs (Cavia porcellus).
abstract: The purpose of this study was to evaluate intraocular pressure (IOP) by means of rebound tonometry, to assess tear production by using the endodontic absorbent paper point tear test (EAPTT) and phenol red thread test (PRTT), and to determine the effects of time of day on IOP and tear production in guinea pigs. The study population comprised 24 healthy adult guinea pigs (12 male, 12 female; 48 eyes) of different breeds and ranging in age from 12 to 15 mo. IOP and tear production were measured at 3 time points (0700, 1500, and 2300) during a 24-h period. Overall values (mean ± 1 SD) were: IOP, 6.81 ± 1.41 mm Hg (range, 4.83 to 8.50); PRTT, 14.33 ± 1.35 mm (range, 12.50 to 16.83); and EAPTT, 8.54 ± 1.08 mm (range, 7.17 to 10.0 mm). In addition, ultrasound biometry was performed by using a B-mode system with linear 8-MHz transducer. This study reports reference values for IOP and tear production in guinea pigs.
authors.affiliation: Department of Clinical Sciences, College of Veterinary Medicine, Karaj Branch, Islamic Azad University, Alborz, Iran. Mehdi_13r@hotmail.com.
authors.forename: Seyed Mehdi
authors.initials: SM
authors.lastname: Rajaei
authors.affiliation: Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
authors.forename: Maneli Ansari
authors.initials: MA
authors.lastname: Mood
authors.affiliation: Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
authors.forename: Reza
authors.initials: R
authors.lastname: Sadjadi
authors.affiliation: Department of Clinical Sciences, Faculty of Specialized Veterinary Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran.
authors.forename: Farzaneh
authors.initials: F
authors.lastname: Azizi
mesh_terms: D000818:Animals; D005260:Female; D006168:Guinea Pigs; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D009799:Ocular Physiological Phenomena; D012016:Reference Values; D013666:Tears / Q000502:physiology*; D014065:Tonometry, Ocular / Q000662:veterinary*