title: [Quality of life and symptoms in patients with chronic depression and anxiety after a self-management training: a randomised controlled trial].
abstract: BACKGROUND
  Evidence-based interventions aimed at patient rehabilitation are not readily available in outpatient mental health care for patients with chronic anxiety and/or depression.
  
  
  OBJECTIVE
  To evaluate the effects that the program 'Rehabilitation through self-management' had on the life and symptoms of patients who had received this programme for six months in an outpatient mental health care setting.
  
  
  METHODS
  As part of a randomised controlled trial, patients were assigned to receive the programme (intervention group) or care as usual (control group). After six months we evaluated the change in the quality of life (World Health Organisation Quality of Life assessment, Brief version (WHOQOL-BREF)) and the change in anxiety symptoms (Beck Anxiety Inventory (BAI)) and depressive symptoms (Patient Health Questionnaire (PHQ-9)) using linear mixed models analysis.
  
  
  RESULTS
  We included 141 patients from 12 participating mental health care institutions. We found no significant difference between the quality of life or symptoms of patients in the intervention group and those in the control groups. Differences in change scores on the WHOQOL-BREF, BAI and PHQ-9 were 0.74 (p=0.63), 0.39 (p=0.81) and -0.07 (p=0.95) respectively. Higher scores on the BAI and PHQ-9 had a negative influence on the effect of the intervention.
  
  
  CONCLUSIONS
  After six months the programme had no significant effect on patients' quality of life or symptoms. These results reflect the chronicity of symptoms and the relation between symptoms and the quality of life in this patient population.
authors.forename: A
authors.initials: A
authors.lastname: Muntingh
authors.forename: M
authors.initials: M
authors.lastname: Laheij
authors.forename: H
authors.initials: H
authors.lastname: Sinnema
authors.forename: M
authors.initials: M
authors.lastname: Zoun
authors.forename: A
authors.initials: A
authors.lastname: van Balkom
authors.forename: A
authors.initials: A
authors.lastname: Schene
authors.forename: J
authors.initials: J
authors.lastname: Spijker
mesh_terms: D001008:Anxiety Disorders / Q000523:psychology*; D002908:Chronic Disease; D003866:Depressive Disorder / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011788:Quality of Life; D012648:Self Care; D016896:Treatment Outcome