title: Dynamic Manipulation of Charged Lipids in Model Membrane for Bio-Microarrays.
abstract: We describe the dynamic manipulation of the charged lipids in a confined geometry where two dispersive factors arising from the random diffusion-based Brownian motion and the field-induced drift of target lipids compete with each other. It is found that the lateral distribution of the target lipids is well controlled through a combined effect of an external electric field and the geometric restrictions by the confinement. The dynamic manipulation scheme for the charged lipids in two-dimension would be useful for understanding the spatial organization of membrane components in a supported lipid membrane mimicking a real cell membrane and for producing membrane-based microarrays.
authors.forename: Yong-Sang
authors.initials: YS
authors.lastname: Ryu
authors.forename: Jeng-Hun
authors.initials: JH
authors.lastname: Suh
authors.forename: Min-Hoi
authors.initials: MH
authors.lastname: Kim
authors.forename: Youngjoo
authors.initials: Y
authors.lastname: Sohn
authors.forename: Sin-Doo
authors.initials: SD
authors.lastname: Lee
mesh_terms: D002462:Cell Membrane / Q000378:metabolism*; D004058:Diffusion; D008563:Membrane Lipids / Q000737:chemistry* / Q000378:metabolism*; D046228:Microarray Analysis / Q000379:methods*
chemical_list: D008563:Membrane Lipids