title: Probable Griseofulvin-Induced Drug Reaction with Eosinophilia and Systemic Symptoms in a Child.
abstract: A 9-year-old boy presented with fever, rash, anterior cervical lymphadenopathy, high liver enzymes, atypical lymphocytosis, and eosinophilia (drug reaction with eosinophilia and systemic symptoms [DRESS]). His history was notable for having taken griseofulvin for 3 weeks prior to onset of these findings. He improved after treatment with oral prednisone. We present a rare case of probable DRESS secondary to griseofulvin.
authors.affiliation: Division of Pediatric Dermatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Smith
authors.affiliation: Division of Dermatology, Department of Pediatrics, Seattle Children's Hospital, Seattle, Washington.
authors.forename: Markus D
authors.initials: MD
authors.lastname: Boos
authors.affiliation: Division of Pediatric Dermatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. mcmahonp@email.chop.edu.
authors.forename: Patrick
authors.initials: P
authors.lastname: McMahon
mesh_terms: D000935:Antifungal Agents / Q000009:adverse effects*; D002648:Child; D063926:Drug Hypersensitivity Syndrome / Q000175:diagnosis* / Q000209:etiology*; D004802:Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis*; D006118:Griseofulvin / Q000009:adverse effects*; D006801:Humans; D008297:Male
chemical_list: D000935:Antifungal Agents; D006118:Griseofulvin