title: Two New Anthraquinones from the Roots of Prismatomeris connata.
abstract: Two new anthraquinones, 4-hydroxy-1,2,3-trimethoxy-7-hydroxymethylanthracene-9,10-dione (1) and 1,2,3-trimethoxy-7-hydroxymethylanthracene-9,10- dione (2), were isolated from the roots of Prismatomeris connata, a Chinese medicinal herb. Their structures were elucidated by spectroscopic analysis. Compound 1 exhibited cytotoxicity against a panel of H1229, HTB 179, A549 and H520 lung tumor cell lines with IC50 values ranging from 12.3 to 20 µM.
authors.forename: Chun-Xiang
authors.initials: CX
authors.lastname: Wang
authors.forename: Sa-Na
authors.initials: SN
authors.lastname: Zhao
authors.forename: Shi-Xiu
authors.initials: SX
authors.lastname: Feng
authors.forename: Xiao-Ping
authors.initials: XP
authors.lastname: Zhang
authors.forename: Tao
authors.initials: T
authors.lastname: Chen
mesh_terms: D000880:Anthraquinones / Q000737:chemistry / Q000302:isolation & purification*; D045744:Cell Line, Tumor; D004354:Drug Screening Assays, Antitumor; D006801:Humans; D015394:Molecular Structure; D018517:Plant Roots / Q000737:chemistry; D019666:Rubiaceae / Q000737:chemistry*
chemical_list: C000611090:1,2,3-trimethoxy-7-hydroxymethylanthracene-9,10-dione; C000611089:4-hydroxy-1,2,3-trimethoxy-7-hydroxymethylanthracene-9,10-dione; D000880:Anthraquinones