title: RETRACTED: Physcion 8-O-β-glucopyranoside induces apoptosis, suppresses invasion and inhibits epithelial to mesenchymal transition of hepatocellular carcinoma HepG2 cells.
abstract: This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy).
  
  This article has been retracted at the request of the Editor-in-Chief.
  
  Panels from Figure 4A appear similar to panels from Figure 1 of the article previously published by Z. Ding, F. Xu, J. Tang, G. Li, P. Jiang, Z. Tang and H. Wu in Neoplasma 63(3) (2016) 351–361 http://www.elis.sk/index.php?page=shop.product_details&flypage=flypage.tpl&product_id=4703&category_id=128&option=com_virtuemart&vmcchk=1&Itemid=1.
  
  One of the conditions of submission of a paper for publication is that authors declare explicitly that the paper has not been previously published and is not under consideration for publication elsewhere. Re-use of any data should be appropriately cited. As such this article represents a misuse of the scientific publishing system. The scientific community takes a very strong view on this matter and apologies are offered to readers of the journal that this was not detected during the submission process.
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Yuqing
authors.initials: Y
authors.lastname: Xing
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Yan
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Peng
authors.initials: P
authors.lastname: Guo
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Jianguang
authors.initials: J
authors.lastname: Zhuang
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China.
authors.forename: Fawei
authors.initials: F
authors.lastname: Qin
authors.affiliation: Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong 250021, China. Electronic address: pburke@126.com.
authors.forename: Jie
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000263:Adenylate Kinase / Q000378:metabolism; D017209:Apoptosis / Q000187:drug effects*; D006528:Carcinoma, Hepatocellular / Q000473:pathology*; D020169:Caspases / Q000378:metabolism; D059447:Cell Cycle Checkpoints / Q000187:drug effects; D002465:Cell Movement / Q000187:drug effects; D049109:Cell Proliferation / Q000187:drug effects; D000076123:DNA (Cytosine-5-)-Methyltransferase 1; D004248:DNA (Cytosine-5-)-Methyltransferases / Q000378:metabolism; D015536:Down-Regulation / Q000187:drug effects; D004642:Emodin / Q000031:analogs & derivatives* / Q000494:pharmacology; D058750:Epithelial-Mesenchymal Transition / Q000187:drug effects*; D005960:Glucosides / Q000494:pharmacology*; D056945:Hep G2 Cells; D006801:Humans; D008113:Liver Neoplasms / Q000473:pathology*; D009361:Neoplasm Invasiveness; D017382:Reactive Oxygen Species / Q000378:metabolism; D015398:Signal Transduction / Q000187:drug effects; D016329:Sp1 Transcription Factor / Q000378:metabolism
chemical_list: D005960:Glucosides; D017382:Reactive Oxygen Species; D016329:Sp1 Transcription Factor; C000613896:physcion 8-O-glucopyranoside; D000076123:DNA (Cytosine-5-)-Methyltransferase 1; D004248:DNA (Cytosine-5-)-Methyltransferases; C000619380:DNMT1 protein, human; D000263:Adenylate Kinase; D020169:Caspases; C008905:physcione; D004642:Emodin
keywords: DNMT1; Physcion 8-O-β-glucopyranoside; ROS; Sp1