title: The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction.
abstract: Current studies evaluating the effect of serum potassium levels on mortality in patients with ST elevation myocardial infarction (STEMI) are lacking. We analyzed retrospectively 3760 patients diagnosed with STEMI. Mean serum potassium levels were categorized accordingly: <3.0, 3.0 to <3.5, 3.5 to <4.0, 4.0 to <4.5, 4.5 to <5.0, 5.0 to <5.5, and ≥5.5mEq/L. The lowest mortality was determined in patients with serum potassium level of 4 to <4.5mEq/L whereas mortality was higher in patients with serum potassium levels of ≥5.0 and <3.5mEq/L. In a multivariable Cox-proportional regression analysis, the mortality risk was higher for patients with serum potassium levels of ≥5mEq/L [hazard ratio (HR), 2.11; 95% confidence interval (CI) 1.23-4.74 and HR, 4.20; 95% CI 1.08-8.23, for patients with potassium levels of 5 to <5.5mEq/L and ≥5.5mEq/L, respectively]. In-hospital and long-term mortality risks were also higher for patients with serum potassium levels of ≤3.5mEq/L. Conversely, ventricular arrhythmias were higher only for patients with serum potassium level of ≤3.5mEq/L. Furthermore, a significant relationship was found between the patient with serum potassium levels of ≤3.5mEq/L and ventricular arrhythmias.
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul,Turkey. Electronic address: drmuhammedkeskin@gmail.com.
authors.forename: Muhammed
authors.initials: M
authors.lastname: Keskin
authors.affiliation: Suruc State Hospital, Sanliurfa, Turkey.
authors.forename: Adnan
authors.initials: A
authors.lastname: Kaya
authors.affiliation: Texas A&M University, Department of Cardiology, TX, USA.
authors.forename: Mustafa Adem
authors.initials: MA
authors.lastname: Tatlısu
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul,Turkey.
authors.forename: Mert İlker
authors.initials: Mİ
authors.lastname: Hayıroğlu
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul,Turkey.
authors.forename: Osman
authors.initials: O
authors.lastname: Uzman
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul,Turkey.
authors.forename: Edibe Betül
authors.initials: EB
authors.lastname: Börklü
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul,Turkey.
authors.forename: Göksel
authors.initials: G
authors.lastname: Çinier
authors.affiliation: Bagcilar Training and Research Hospital, Department of Cardiology Istanbul, Turkey.
authors.forename: Yasin
authors.initials: Y
authors.lastname: Çakıllı
authors.affiliation: Diyarbakir Gazi Yasargil Training and Research Hospital, Department of Cardiology, Diyarbakir, Turkey.
authors.forename: Barış
authors.initials: B
authors.lastname: Yaylak
authors.affiliation: Siyami Ersek Thoracic and Cardiovascular Surgery Center, Training and Research Hospital, Department of Cardiology, Istanbul,Turkey.
authors.forename: Mehmet
authors.initials: M
authors.lastname: Eren
mesh_terms: D000368:Aged; D015415:Biomarkers / Q000097:blood; D005260:Female; D005500:Follow-Up Studies; D017052:Hospital Mortality / Q000639:trends*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009026:Mortality / Q000639:trends; D011188:Potassium / Q000097:blood*; D012189:Retrospective Studies; D000072657:ST Elevation Myocardial Infarction / Q000097:blood* / Q000401:mortality*; D013997:Time Factors
chemical_list: D015415:Biomarkers; D011188:Potassium
keywords: Mortality; Myocardial infarction; Potassium; Ventricular arrhythmia