title: Isolates and antibiotic susceptibilities of endophthalmitis in postcataract surgery: a 12-year review of culture-proven cases.
abstract: The purpose of this study was to investigate the spectrum of organisms causing endophthalmitis after cataract surgery in a tertiary medical center in Taiwan and the antibiotic susceptibilities. This was a retrospective case series study. Patients with endophthalmitis after cataract surgery from January 2004 to July 2015 were reviewed. The outcome measures included the identification of isolates, antibiotic susceptibilities, and final visual outcomes. Twenty-one organisms were isolated from 19 cases. The most common organisms were Enterococcus in 38.1 %, especially Enterococcus faecalis, followed by Staphylococcus epidermidis in 28.6 % and Staphylococcus aureus in 9.5 %. All of the Gram-positive isolates tested were susceptible to vancomycin (100 %), and ceftazidime and amikacin were susceptible for Gram-negative organisms. The Gram-positive organisms remain to be the predominant cause of postoperative endophthalmitis, and Enterococcus species has had an increasing incidence. Vancomycin is still the most powerful antibiotic for Gram-positive organisms, while ceftazidime and amikacin are effective for Gram-negative bacteria.
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.|Department of Ophthalmology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
authors.forename: Yu Ti
authors.initials: YT
authors.lastname: Teng
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Mei Ching
authors.initials: MC
authors.lastname: Teng
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Hsi Kung
authors.initials: HK
authors.lastname: Kuo
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Po Chiung
authors.initials: PC
authors.lastname: Fang
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Pei Chang
authors.initials: PC
authors.lastname: Wu
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Chih Hsin
authors.initials: CH
authors.lastname: Chen
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: Ming Tse
authors.initials: MT
authors.lastname: Kuo
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan.
authors.forename: I Hui
authors.initials: IH
authors.lastname: Yang
authors.affiliation: Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Kaohsiung, Taiwan. f75622@cgmh.org.tw.
authors.forename: Yung Jen
authors.initials: YJ
authors.lastname: Chen
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology*; D001419:Bacteria / Q000187:drug effects / Q000302:isolation & purification*; D002387:Cataract Extraction / Q000009:adverse effects*; D009877:Endophthalmitis / Q000188:drug therapy / Q000382:microbiology; D015818:Eye Infections, Bacterial / Q000188:drug therapy* / Q000382:microbiology; D005260:Female; D005544:Forecasting; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D012189:Retrospective Studies; D013530:Surgical Wound Infection / Q000188:drug therapy* / Q000382:microbiology; D014792:Visual Acuity; D014822:Vitreous Body / Q000382:microbiology*
chemical_list: D000900:Anti-Bacterial Agents
keywords: Antibiotic susceptibilities; Endophthalmitis; Microorganisms; Postoperative endophthalmitis