title: Influence of food intake on the QT and QT/RR relation.
abstract: There are conflicting data on the influence of meal intake on the QT interval.
  
  
  
  Ten healthy subjects were studied before and after a standardized breakfast and lunch with a sequence of supine resting, standing and exercise. Data collection was performed using a 12-lead Holter with semi-automated analysis. QT correction was performed using Fridericia (QTcF) correction formula and a subject-specific method based on individual QT/RR-regression (QTcI).
  
  
  
  Meal intake induced significant changes in HR (p<0.001), but not in QTcF (p=0.512) or QTcI (p=0.739). Postural analysis showed only significant differences in supine position for HR (p=0.010), not when standing or during exercise.
  
  
  
  Food intake induced an increase in heart rate limited to supine position. Using QTcF and QTcI no QTc changes were found.
authors.affiliation: Department Cardiology, University Hospitals Leuven, Leuven, Belgium.
authors.forename: Bram
authors.initials: B
authors.lastname: Sciot
authors.affiliation: Department Cardiology, University Hospitals Leuven, Leuven, Belgium; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium. Electronic address: bert.vandenberk@med.kuleuven.be.
authors.forename: Bert
authors.initials: B
authors.lastname: Vandenberk
authors.forename: Suzy
authors.initials: S
authors.lastname: Huijghebaert
authors.affiliation: Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, University of Leuven, Leuven, Belgium; IMinds Medical IT, Leuven, Belgium.
authors.forename: Griet
authors.initials: G
authors.lastname: Goovaerts
authors.affiliation: Department of Electrical Engineering (ESAT), STADIUS Center for Dynamical Systems, Signal Processing and Data Analytics, University of Leuven, Leuven, Belgium; IMinds Medical IT, Leuven, Belgium.
authors.forename: Sabine
authors.initials: S
authors.lastname: Van Huffel
authors.affiliation: Department Cardiology, University Hospitals Leuven, Leuven, Belgium; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
authors.forename: Joris
authors.initials: J
authors.lastname: Ector
authors.affiliation: Department Cardiology, University Hospitals Leuven, Leuven, Belgium; Department of Cardiovascular Sciences, University of Leuven, Leuven, Belgium.
authors.forename: Rik
authors.initials: R
authors.lastname: Willems
mesh_terms: D000328:Adult; D004435:Eating / Q000502:physiology*; D015716:Electrocardiography, Ambulatory / Q000592:standards*; D005260:Female; D006329:Heart Conduction System / Q000502:physiology*; D006339:Heart Rate / Q000502:physiology*; D000070276:Heart Rate Determination / Q000592:standards*; D006801:Humans; D008297:Male; D019518:Postprandial Period / Q000502:physiology; D012016:Reference Values; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D016683:Supine Position / Q000502:physiology
keywords: Heart rate; Meal intake; QT correction; QT interval; Thorough QT studies