title: Silk Device for the Treatment of Intracranial Aneurysms. Part 1: Peri-Procedural Results, Technical Aspects and Learning Curve.
abstract: OBJECTIVE
  We evaluated the procedural outcomes of intracranial aneurysm treatment with the Silk device and its relation with operator experience. We also detailed some technical points we learned throughout our experience.
  
  
  METHODS
  One hundred and six consecutive patients with intracranial aneurysms treated using Silk (BaltExtrusion, Montmorency, France) stent between October 2010 and November 2013 were included. Patients were evaluated in terms of age, sex, aneurysm size, location, technical success, and adverse events.
  
  
  RESULTS
  There were 106 patients (71 female) undergoing 116 procedures with a mean age of 49.8 (range: 3-78 years). Mean aneurysm size was 10.7±8.0 (range, 2-40 mm). Technical success of the procedures was 96.5%. Adverse event rate was 11.2%. Among adverse events, there were 4 adverse events without complications, 2 mild complications, 7 severe complications, 4 of which resulted with death. The adverse event rate was significantly higher during the first half of the operator's experience. The rate of adverse events seemed to stabilize after around 50 patients. Adverse events, regardless of the presence or absence of a clinical complication, were more frequent in aneurysms larger than 18.5 mm.
  
  
  CONCLUSIONS
  Safety of flow-diverter (FD) placement for intracranial aneurysms increases with operator experience. Training programs in endovascular management of cerebrovascular diseases and relevant fellowship curricula must be adapted to include sufficient flow diverter experience. The learning curve needs to be kept in mind when studies comparing different FD devices or those comparing other treatments to FDS are planned.
authors.affiliation: Ankara Numune Training and Research Hospital, Department of Neurology, Ankara, Turkey.
authors.forename: Erdem
authors.initials: E
authors.lastname: Gurkas
authors.forename: Tunca
authors.initials: T
authors.lastname: Kaya
authors.forename: Ergun
authors.initials: E
authors.lastname: Daglioglu
authors.forename: Ilkay
authors.initials: I
authors.lastname: Akmangit
authors.forename: Deniz
authors.initials: D
authors.lastname: Belen
authors.forename: Ahmet
authors.initials: A
authors.lastname: Peker
authors.forename: Dogan
authors.initials: D
authors.lastname: Dede
authors.forename: Anil
authors.initials: A
authors.lastname: Arat
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002648:Child; D002675:Child, Preschool; D004621:Embolization, Therapeutic / Q000295:instrumentation* / Q000379:methods; D057510:Endovascular Procedures / Q000295:instrumentation* / Q000379:methods; D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000628:therapy*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D015607:Stents; D016896:Treatment Outcome; D055815:Young Adult