title: Multimodality Treatment in Ewing's Sarcoma Family Tumors of the Maxilla and Maxillary Sinus: Review of the Literature.
abstract: The Ewing sarcoma family of tumors (ESFT) encompasses a group of highly aggressive, morphologically similar, malignant neoplasms sharing a common spontaneous genetic translocation that affect mostly children and young adults. These predominantly characteristic, small round-cell tumors include Ewing's sarcoma of the bone and soft tissue, as well as primitive neuroectodermal tumors (PNETs) involving the bone, soft tissue, and thoracopulmonary region (Askin's tumor). Extraosseous ESFTs are extremely rare, especially in the head and neck region, where literature to date consists of sporadic case reports and very small series. We hereby present a review of the literature published on ESFTs reported in the maxilla and maxillary sinus region from 1968 to 2016.
authors.affiliation: Division of Medical Oncology, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
authors.forename: David
authors.identifier: 0000-0001-7966-0711
authors.initials: D
authors.lastname: Thorn
authors.affiliation: Division of Medical Oncology, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
authors.forename: Christoph
authors.initials: C
authors.lastname: Mamot
authors.affiliation: Division of Medical Oncology, University Hospital Basel, 4031 Basel, Switzerland.
authors.forename: Fatime
authors.initials: F
authors.lastname: Krasniqi
authors.affiliation: Division of Ear, Nose and Throat, Head & Neck Surgery, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
authors.forename: Frank
authors.initials: F
authors.lastname: Metternich
authors.affiliation: Division of Ear, Nose and Throat, Head & Neck Surgery, Cantonal Hospital Aarau, 5001 Aarau, Switzerland.
authors.forename: Sven
authors.identifier: 0000-0003-0717-5607
authors.initials: S
authors.lastname: Prestin