title: G CSF: A First Line Therapy for Autoimmune Neutropenia?
abstract: This paper studies the use of recombinant human Granulocyte Colony Stimulating Factor (rh G CSF) as a single treatment modality in serologically proven autoimmune neutropenia. We present six cases, all of whom had severe neutropenia resulting in recurrent infections and oral ulceration. A response, characterised by an increase in mean neutrophil count and a reduction in infective episodes, was demonstrated in all cases.
authors.affiliation: a Department of Haematology , Royal United Hospital , Combe Park, Bath , BA1 3NG , UK.
authors.forename: S A
authors.initials: SA
authors.lastname: Wexler
authors.affiliation: a Department of Haematology , Royal United Hospital , Combe Park, Bath , BA1 3NG , UK.
authors.forename: S H
authors.initials: SH
authors.lastname: Otton
authors.affiliation: a Department of Haematology , Royal United Hospital , Combe Park, Bath , BA1 3NG , UK.
authors.forename: C R
authors.initials: CR
authors.lastname: Singer
authors.affiliation: a Department of Haematology , Royal United Hospital , Combe Park, Bath , BA1 3NG , UK.
authors.forename: J G
authors.initials: JG
authors.lastname: Smith
keywords: Autoimmune; G CSF; neutropenia