title: Reticular Appearance on Gadolinium-enhanced T1- and Diffusion-weighted MRI, and Low Apparent Diffusion Coefficient Values in Microcystic Meningioma Cysts.
abstract: OBJECTIVE
  Microcystic meningioma, a rare meningioma subtype, can present diagnostic difficulty. We aimed to investigate the historadiological properties of microcystic meningioma using conventional magnetic resonance imaging (MRI) and diffusion-weighted imaging (DWI) analysis.
  
  
  METHODS
  We retrospectively analyzed conventional MRI and DWI results of six microcystic meningioma cases by examining their appearance and determining their apparent diffusion coefficient (ADC) values. The ADC values of the intratumoral components were normalized with ADC values of the cerebrospinal fluid in the lateral ventricle (ADC ratios). As cystic formations are frequently associated with microcystic meningiomas, their MRI characteristics were compared with the imaging data from 11 cystic meningiomas of non-microcystic subtypes.
  
  
  RESULTS
  We found that cysts in microcystic meningioma tended to have a reticular appearance on DWI, as they did on gadolinium-enhanced T1-weighted imaging. Additionally, these reticular cysts had significantly lower ADC ratios than microcystic non-reticular and non-microcystic cysts. These DWI characteristics likely reflect the histological properties of microcystic meningioma.
  
  
  CONCLUSIONS
  A reticular appearance on gadolinium-enhanced T1-weighted MRI and DWI, and cyst formation with relatively low ADC values can be diagnostic markers of microcystic meningiomas.
authors.affiliation: Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital, 2-4-20, Ogimachi, 530-8480, Osaka, Japan.
authors.forename: Yukinori
authors.initials: Y
authors.lastname: Terada
authors.affiliation: Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital, 2-4-20, Ogimachi, 530-8480, Osaka, Japan. htoda-nsu@umin.ac.jp.
authors.forename: Hiroki
authors.identifier: http://orcid.org/0000-0002-1596-4131
authors.initials: H
authors.lastname: Toda
authors.affiliation: Department of Radiology, Tazuke Kofukai Medical Research Institute and Kitano Hospital, Osaka, Japan.
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Okumura
authors.affiliation: Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital, 2-4-20, Ogimachi, 530-8480, Osaka, Japan.
authors.forename: Naokado
authors.initials: N
authors.lastname: Ikeda
authors.affiliation: Department of Pathology, Tazuke Kofukai Medical Research Institute and Kitano Hospital, Osaka, Japan.
authors.forename: Yoshiaki
authors.initials: Y
authors.lastname: Yuba
authors.affiliation: Department of Medical Health Science, Himeji Dokkyo University, Himeji, Japan.
authors.forename: Toshiro
authors.initials: T
authors.lastname: Katayama
authors.affiliation: Department of Neurosurgery, Tazuke Kofukai Medical Research Institute and Kitano Hospital, 2-4-20, Ogimachi, 530-8480, Osaka, Japan.
authors.forename: Koichi
authors.initials: K
authors.lastname: Iwasaki
mesh_terms: D000368:Aged; D003560:Cysts / Q000000981:diagnostic imaging*; D038524:Diffusion Magnetic Resonance Imaging; D005260:Female; D005682:Gadolinium; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male; D008579:Meningioma / Q000000981:diagnostic imaging*; D008875:Middle Aged; D012189:Retrospective Studies
chemical_list: D005682:Gadolinium
keywords: Apparent diffusion coefficient value; Cystic meningioma; Diffusion-weighted imaging; Magnetic resonance imaging; Microcystic meningioma