title: Role of Small Airways in Asthma.
abstract: Asthma is an inflammatory condition of both the small and large airways. Recently the small airways have gained attention as studies have shown significant inflammation in the small airways in all severities of asthma. This inflammation has correlated with peripheral airway resistance and as a result, noninvasive methods to reliably measure small airways have been pursued. In addition, recent changes in asthma inhalers have led to alterations in drug formulations and the development of extrafine particle inhalers that improve delivery to the distal airways.
authors.affiliation: Division of Allergy and Clinical Immunology, Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA. Electronic address: FinkasL@NJHealth.org.
authors.forename: Lindsay K
authors.initials: LK
authors.lastname: Finkas
authors.affiliation: Department of Medicine, National Jewish Health, 1400 Jackson Street, Denver, CO 80206, USA.
authors.forename: Richard
authors.initials: R
authors.lastname: Martin
mesh_terms: D000403:Airway Resistance; D001249:Asthma / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology* / Q000628:therapy; D045853:Exhalation; D006801:Humans; D008168:Lung / Q000503:physiopathology*; D009569:Nitric Oxide; D012129:Respiratory Function Tests
chemical_list: D009569:Nitric Oxide
keywords: Asthma; Extrafine particle inhalers; Nocturnal asthma; Small airways