title: An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex.
abstract: This paper describes a test method for measuring the mechanical properties of small, nonlinear membrane samples from a rat model for pulmonary hypertension. The size and nonlinearity of the pulmonary artery samples poses a challenge for developing a test method that will generate quality, reproducible data in the pressure range experienced by the hypertensive pulmonary artery. The experimental method described here has sufficient precision to yield a combined relative standard uncertainty of 4 %. The method is calibrated against 75 µm thick latex and the data agree well with the neo-Hookian model.
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: E S
authors.initials: ES
authors.lastname: Drexler
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: A J
authors.initials: AJ
authors.lastname: Slifka
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: J E
authors.initials: JE
authors.lastname: Wright
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: C N
authors.initials: CN
authors.lastname: McCowan
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: D S
authors.initials: DS
authors.lastname: Finch
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: T P
authors.initials: TP
authors.lastname: Quinn
authors.affiliation: National Institute of Standards and Technology, Boulder, CO 80305.
authors.forename: J D
authors.initials: JD
authors.lastname: McColskey
authors.affiliation: Department of Pediatrics, Division of Cardiology, University of Colorado, Health Sciences Center, Denver, CO 80218.
authors.forename: D D
authors.initials: DD
authors.lastname: Ivy
authors.affiliation: Department of Pediatrics, Division of Cardiology, University of Colorado, Health Sciences Center, Denver, CO 80218Department of Mechanical Engineering, University of Colorado, Boulder, CO 80309.
authors.forename: R
authors.initials: R
authors.lastname: Shandas
keywords: apparatus; biaxial test; latex; mechanical properties; nonlinear material; pulmonary hypertension; rat pulmonary artery