title: ACR Appropriateness Criteria® Borderline and Unresectable Pancreas Cancer.
abstract: The American College of Radiology Appropriateness Criteria® are evidence-based guidelines for specific clinical conditions that are reviewed every 3 years by a multidisciplinary expert panel. The guideline development and review include an extensive analysis of current medical literature from peer-reviewed journals and the application of a well-established consensus methodology (modified Delphi) to rate the appropriateness of imaging and treatment procedures by the panel. In those instances where evidence is lacking or not definitive, expert opinion may be used to recommend imaging or treatment. The panel reviewed the pertinent literature and voted on five variants to establish appropriate recommended treatment of borderline and unresectable pancreatic cancer. The guidelines reviewed the use of radiation, chemotherapy, and surgery. Radiation technique, dose, and targets were evaluated, as was the recommended chemotherapy, administered either alone or concurrently with radiation. This report will aid clinicians in determining guidelines for the optimal treatment of borderline and unresectable pancreatic cancer.
authors.forename: William
authors.initials: W
authors.lastname: Small
authors.forename: John P
authors.initials: JP
authors.lastname: Hayes
authors.forename: W Warren
authors.initials: WW
authors.lastname: Suh
authors.forename: May
authors.initials: M
authors.lastname: Abdel-Wahab
authors.forename: Ross A
authors.initials: RA
authors.lastname: Abrams
authors.forename: Nilofer
authors.initials: N
authors.lastname: Azad
authors.forename: Prajnan
authors.initials: P
authors.lastname: Das
authors.forename: Jadranka
authors.initials: J
authors.lastname: Dragovic
authors.forename: Karyn A
authors.initials: KA
authors.lastname: Goodman
authors.forename: Salma K
authors.initials: SK
authors.lastname: Jabbour
authors.forename: William E
authors.initials: WE
authors.lastname: Jones
authors.forename: Andre A
authors.initials: AA
authors.lastname: Konski
authors.forename: Albert C
authors.initials: AC
authors.lastname: Koong
authors.forename: Rachit
authors.initials: R
authors.lastname: Kumar
authors.forename: Percy
authors.initials: P
authors.lastname: Lee
authors.forename: Timothy M
authors.initials: TM
authors.lastname: Pawlik
authors.forename: Joseph M
authors.initials: JM
authors.lastname: Herman
mesh_terms: D059248:Chemoradiotherapy / Q000379:methods; D032921:Consensus; D017408:Guidelines as Topic; D006801:Humans; D009367:Neoplasm Staging; D010180:Pancreatectomy; D010190:Pancreatic Neoplasms / Q000473:pathology* / Q000628:therapy*; D011871:Radiology; D016896:Treatment Outcome; D014481:United States