title: [The use of controlled physical training in patients with acute coronary syndrome treated with intervention - assessment of effects on biochemical parameters and functional myocardial].
abstract: Diseases of the cardiovascular system is one of the most common causes of death among people over 65 years. Due to its course and incidence are a major cause of disability and impaired quality of life for seniors, as well as a serious economic problem in health care. Important role in the prevention of cardiovascular disease plays making systematic physical activity, which is a component of any rehabilitation program. Regular physical training by doing cardio-and vasoprotective has a beneficial effect on cardiovascular status and physical performance in patients with diagnosed coronary heart disease, regardless of age.
  
  
  OBJECTIVE
  The aim of this study was to evaluate the effect of controlled exercise on selected biochemical parameters and functional myocardial infarction.
  
  
  METHODS
  A group of 89 patients were divided into 3 subgroups. In group I (n = 30) was performed 2 weeks cardiac rehabilitation program, in group II (n = 30) 4 weekly. Streamline the program consisted of a series of interval training performed using a bicycle ergometer and general exercise. The remaining group (gr. III, n = 29) participated in individually selected training program. In all subjects before and after the training cycle underwent thoracic impedance plethysmography, also determined the level of plasma natriuretic peptide NT-proBNP and echocardiography and exercise test.
  
  
  RESULTS
  After training, in groups, which carried out a controlled physical training, improvement was observed: exercise capacity of patients respectively in group I (p = 0.0003), group II (p = 0.0001) and group III (p = 0.032), stroke volume SV, cardiac output CO and global myocardial contractility, there was also reduction in the concentration of natriuretic peptide NT-proBNP. Furthermore, the correlation between the results shown pletyzmography parameters and NT-proBNP, SV, CO and EF.
  
  
  CONCLUSIONS
  Regular physical training as part of the cardiac rehabilitation has a beneficial effect on biochemical parameters and functional myocardial infarction in patients with ACS. Size of the observed changes conditioned by the nature and duration of the training.
authors.affiliation: Clinic of Internal Medicine and Cardiac Rehabilitation, Medical University of Lodz, Poland.
authors.forename: Joanna
authors.initials: J
authors.lastname: Kapusta
authors.affiliation: Clinic of Internal Medicine and Cardiac Rehabilitation, Medical University of Lodz, Poland.
authors.forename: Anna
authors.initials: A
authors.lastname: Kapusta
authors.affiliation: Clinic of Internal Medicine and Cardiac Rehabilitation, Medical University of Lodz, Poland.
authors.forename: Lucjan
authors.initials: L
authors.lastname: Pawlicki
authors.affiliation: Clinic of Internal Medicine and Cardiac Rehabilitation, Medical University of Lodz, Poland.
authors.forename: Robert
authors.initials: R
authors.lastname: Irzmański
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood / Q000503:physiopathology / Q000534:rehabilitation*; D000328:Adult; D000368:Aged; D002307:Cardiography, Impedance; D005080:Exercise Test; D005081:Exercise Therapy; D005260:Female; D006321:Heart / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D020097:Natriuretic Peptide, Brain / Q000097:blood; D010446:Peptide Fragments / Q000097:blood
chemical_list: D010446:Peptide Fragments; C109794:pro-brain natriuretic peptide (1-76); D020097:Natriuretic Peptide, Brain
keywords: acute coronary syndrome; cardiac rehabilitation; interval training; ischemic heart disease; physical fitness