title: Thermodynamics of Complexation between Thiourea-based Receptor and Acetate in Water/Acetonitrile Mixture.
abstract: A thiourea-based receptor has been extensively studied for selective anion recognition for reasons of its strong hydrogen bond donor ability. In the present study, the thermodynamics of complexation between a thiourea-based receptor and acetate was examined in a water/acetonitrile mixture. The receptor used in this study was N,N'-bis(p-nitrophenyl)thiourea (BNPTU). UV/vis spectroscopic titration and isothermal titration calorimetry (ITC) experiments clearly revealed endothermic and entropy-driven complexation of BNPTU with acetate in water/acetonitrile mixtures. Since the endothermic peaks found in water/acetonitrile mixtures were about three times greater than those in acetonitrile, it appears that preferential hydration of both receptor and acetate was responsible for the endothermic and entropy-driven complexation reaction. The thermodynamic properties found in this study have the potential to contribute to the design of a thiourea-based anion receptor.
authors.affiliation: College of Science, Ibaraki University.
authors.forename: Takaya
authors.initials: T
authors.lastname: Suzuki
authors.forename: Yuuta
authors.initials: Y
authors.lastname: Shibuya
authors.forename: Takaya
authors.initials: T
authors.lastname: Sato
authors.forename: Seiichi
authors.initials: S
authors.lastname: Nishizawa
authors.forename: Itaru
authors.initials: I
authors.lastname: Sato
authors.forename: Akira
authors.initials: A
authors.lastname: Yamaguchi