title: Atypical Proliferating Trichilemmal Cyst with Malignant Breast Skin Transformation: A Case Report and Review of the Literature.
abstract: Proliferating trichilemmal tumors (PTTs) are benign adnexal skin neoplasms that arise from the outer root sheath of the hair follicle. These tumors are most commonly observed on the scalp and occur, most of the time, in elderly women. Malignant transformation of these neoplasms is a rare event; less than 50 cases have been reported in the English medical literature. We present the case of a 39-year-old Hispanic woman with a tumor located on the skin of one of her breasts that in her third surgical procedure the histologic examination revealed the presence of a malignant proliferating trichilemmal tumor (MPTT). Furthermore, a review of the medical literature and a discussion of the clinical and pathologic features of this rare entity are provided.
authors.affiliation: Departamento de Oncología Mamaria Quirúrgica, Instituto de Enfermedades de la Mama (IEM), La Fundación del Cáncer de Mama (FUCAM), 40980 Mexico City, Mexico; Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Huixquilucan, MEX, Mexico.
authors.forename: Marino Antonio
authors.initials: MA
authors.lastname: Capurso-García
authors.affiliation: Departamento de Patología, Instituto de Enfermedades de la Mama (IEM), La Fundación del Cáncer de Mama (FUCAM), 40980 Mexico City, Mexico.
authors.forename: Verónica
authors.initials: V
authors.lastname: Bautista-Piña
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Huixquilucan, MEX, Mexico.
authors.forename: Alan
authors.initials: A
authors.lastname: Pomerantz
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Huixquilucan, MEX, Mexico.
authors.forename: Javier Andrés
authors.initials: JA
authors.lastname: Galnares-Olalde
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Huixquilucan, MEX, Mexico.
authors.forename: Ruben
authors.initials: R
authors.lastname: Blachman-Braun
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Huixquilucan, MEX, Mexico.
authors.forename: Sergio
authors.initials: S
authors.lastname: Rodríguez-Rodríguez
authors.affiliation: Facultad de Ciencias de la Salud, Universidad Anáhuac México Norte, 52786 Huixquilucan, MEX, Mexico.
authors.forename: Monica
authors.initials: M
authors.lastname: Goldberg-Murow