title: Bilateral Facial Nerve Palsy in Acute B Cell Lymphoblastic Leukemia: A Case Report and Review of the Literature.
abstract: Acute lymphoblastic leukemia (ALL) is a haematological malignancy that can involve the central nervous system (CNS). Less than 10 % of patients with ALL have CNS involvement at presentation. The cranial nerve most commonly affected is cranial nerve VII although bilateral involvement is rare. Management and outcomes of these patients are not well understood. Moreover bilateral Bells palsy as a presenting symptom of ALL is extremely uncommon. We report a very unusual presentation of ALL with bilateral facial nerve palsy, and discuss the management strategies and outcomes for patients with ALL that present with cranial nerve palsies.
authors.affiliation: Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX USA.
authors.forename: Shiraj
authors.initials: S
authors.lastname: Sen
authors.affiliation: Department of Internal Medicine, UT Southwestern Medical Center, Dallas, TX USA.
authors.forename: Arjun
authors.initials: A
authors.lastname: Gupta
authors.affiliation: Department of Pathology, UT Southwestern Medical Center, Dallas, TX USA.
authors.forename: Paul
authors.initials: P
authors.lastname: Friedman
authors.affiliation: Department of Hematology-Oncology, UT Southwestern Medical Center, Seay Biomedical Building, 2201 Inwood Road, Dallas, TX 75390-8562 USA.
authors.forename: Harris V
authors.initials: HV
authors.lastname: Naina
keywords: Acute lymphoblastic leukemia; Bells palsy; CNS leukemia; Whole brain irradiation