title: Worldwide 10-Year Systematic Review of Treatment Trends in Fibula Free Flap for Mandibular Reconstruction.
abstract: OBJECTIVE
  The purpose of this study was to describe the trends pertaining to the use of the fibula free flap for mandibular reconstruction during the past 10 years.
  
  
  METHODS
  A systematic review for publications on the fibula free flap in mandibular reconstruction in the PubMed and Scopus databases was performed from January 1, 2005 until December 31, 2014. Publications were classified by topic, number of patients, and country of origin. The study period was split into 2 periods. The first 5-year period was compared with the second 5-year period.
  
  
  RESULTS
  Eighty-five publications were identified. There was an increase in publications regarding restorative decision making (11 vs 9), surgical techniques (13 vs 6), outcomes (20 vs 10), and computer-aided design and computer-aided manufacturing (CAD-CAM; 8 vs 2) in the second 5-year period. The number of patients reported also increased in publications on surgical techniques (1,085 vs 59), outcomes (777 vs 254), bisphosphonate-related osteonecrosis of the jaw and osteoradionecrosis (165 vs 28), and CAD-CAM (65 vs 15) in the second 5-year period. The United States, India, China, and Europe produced most of the publications.
  
  
  CONCLUSIONS
  In the past 10 years, there was a surge in publications on the use of the fibula free flap for mandibular reconstruction. There was a 1.8-fold increase in the number of publications and a 3.4-fold increase in the number of patients undergoing this method of mandibular reconstruction in the second 5-year period. Publications from the United States, India, and China contributed to a large increase in the number of patients in the second 5-year period. More interest in CAD-CAM technology was seen in the second 5-year period that was not seen in the first 5-year period.
authors.affiliation: Director, Division of Prosthetics, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY.
authors.forename: Devin
authors.initials: D
authors.lastname: Okay
authors.affiliation: Former Chief Resident, Division of Oral and Maxillofacial Surgery, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY. Electronic address: Halshetawi@gmail.com.
authors.forename: Al Haitham
authors.initials: AH
authors.lastname: Al Shetawi
authors.affiliation: Fellow, Division of Head and Neck Surgical Oncology, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY.
authors.forename: Sami P
authors.initials: SP
authors.lastname: Moubayed
authors.affiliation: Chief Resident, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY.
authors.forename: Moustafa
authors.initials: M
authors.lastname: Mourad
authors.affiliation: Chief, Division of Oral and Maxillofacial Surgery, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY.
authors.forename: Daniel
authors.initials: D
authors.lastname: Buchbinder
authors.affiliation: Chief, Division of Head and Neck Surgical Oncology, Department of Otolaryngology-Head and Neck Surgery, Mount Sinai Beth Israel, New York, NY.
authors.forename: Mark L
authors.initials: ML
authors.lastname: Urken
mesh_terms: D015706:Bibliometrics; D002681:China; D005060:Europe; D005360:Fibula / Q000637:transplantation*; D058752:Free Tissue Flaps / Q000706:statistics & numerical data* / Q000639:trends; D006801:Humans; D007194:India; D063175:Mandibular Reconstruction / Q000379:methods / Q000639:trends*; D010818:Practice Patterns, Physicians' / Q000639:trends*; D014481:United States