title: Untangling the complex relationship between dietary acid load and glucocorticoid metabolism.
abstract: The kidney's maintenance of the metabolic component of acid-base homeostasis is critical for normal health. The study by Esche and colleagues in this issue of Kidney International shows that normal children with higher levels of renal net acid excretion and of dietary acid loads have stimulation of glucocorticoid hormone metabolism. Thus, normal variations in dietary acid intake and renal net acid excretion have important biological correlates.
authors.affiliation: Division of Nephrology, Hypertension and Renal Transplantation, University of Florida College of Medicine, Gainesville, Florida, USA; and Nephrology and Hypertension Section, Gainesville VA Medical Center, Gainesville, Florida, USA. Electronic address: david.weiner@medicine.ufl.edu.
authors.forename: I David
authors.initials: ID
authors.lastname: Weiner
mesh_terms: D000136:Acid-Base Equilibrium; D000143:Acids; D004032:Diet; D005938:Glucocorticoids; D006801:Humans; D007668:Kidney
chemical_list: D000143:Acids; D005938:Glucocorticoids
keywords: acid-base; ammonia; glucocorticoid hormones; net acid excretion