title: Macular Effects of Silicone Oil Tamponade: Optical Coherence Tomography Findings During and After Silicone Oil Removal.
abstract: To investigate retinal morphologic changes during silicone oil tamponade and after its removal using spectral domain OCT (SD-OCT) imaging.
  
  
  
  Retrospective review of 12 patients who underwent silicone oil tamponade for repair of retinal detachments. Macular OCT scans and volumetric thickness maps were examined qualitatively and quantitatively.
  
  
  
  Volumetric OCT revealed two distinct patterns during silicone oil: macular thickening (Group A) and macular thinning (Group B). In Group A, mean foveal thickness (507 ± 169 µm vs. 407 ± 163 µm, p = 0.003) and mean macular volume (11.6 ± 2.4 mm3vs. 9.9 ± 1.5 mm3) were significantly increased during tamponade compared to post-oil removal. Group B had significantly decreased mean foveal thickness (210 ± 38 µm vs. 276 ± 58 µm, p = 0.009) and macular volume (7.3 ± 1.8 mm3vs. 8.4 ± 1.8 mm3) during tamponade. Importantly, resolution of macular changes occurred without further intervention and was associated with improved visual acuity in both groups.
  
  
  
  Our series suggests that when faced with unexplained macular edema or macular thinning during tamponade, silicone oil removal alone can achieve resolution of these structural changes.
authors.affiliation: a Department of Ophthalmology , New York University School of Medicine , New York City , New York , USA.
authors.forename: Danielle M
authors.initials: DM
authors.lastname: Lo
authors.affiliation: b Casey Eye Institute, Oregon Health and Science University , Portland , Oregon , USA.
authors.forename: Christina J
authors.initials: CJ
authors.lastname: Flaxel
authors.affiliation: c Department of Ophthalmology , Feinberg School of Medicine, Northwestern University , Chicago , Illinois , USA.
authors.forename: Amani A
authors.initials: AA
authors.lastname: Fawzi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004322:Drainage / Q000379:methods*; D058450:Endotamponade; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D012160:Retina / Q000473:pathology*; D012163:Retinal Detachment / Q000175:diagnosis / Q000503:physiopathology / Q000601:surgery*; D012189:Retrospective Studies; D012827:Silicone Oils; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology; D014821:Vitrectomy
chemical_list: D012827:Silicone Oils
keywords: Optical coherence tomography; retinal detachment; silicone oil tamponade