title: The use of low-dose sodium valproate in the management of neuropathic pain: illustrative case series.
abstract: Anti-epileptic drugs are commonly used in the management of neuropathic pain. Sodium valproate, however, is an anti-epileptic drug that is not commonly used. We report four patients with neuropathic pain who responded very well to the initiation of low-dose oral sodium valproate. Low-dose sodium valproate may have a role in managing neuropathic pain, especially when other first-line agents are unsuccessful or relatively contraindicated.
authors.affiliation: Department of Anaesthetics, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
authors.forename: K
authors.initials: K
authors.lastname: Pirapakaran
authors.affiliation: Pain Management Centre, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.
authors.forename: A
authors.initials: A
authors.lastname: Aggarwal
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000927:Anticonvulsants / Q000008:administration & dosage*; D001315:Australia; D005260:Female; D006801:Humans; D008875:Middle Aged; D009437:Neuralgia / Q000188:drug therapy*; D016896:Treatment Outcome; D014635:Valproic Acid / Q000008:administration & dosage*
chemical_list: D000927:Anticonvulsants; D014635:Valproic Acid
keywords: neuralgia; pain; valproic acid