title: Occurrence of Double Monoclonal Bands on Protein Electrophoresis: An Unusual Finding.
abstract: Various techniques of protein electrophoresis are used for detection of monoclonal proteins/paraproteins in serum and/or urine of patients with monoclonal gammopathies. These are detected as the so-called 'M' bands (monoclonal bands) on serum protein electrophoresis and/or immunofixation electrophoresis. In most cases, a single M-band is detected. However, more than one M-band can be detected in the samples of a minor proportion of patients. This condition is termed as 'double gammopathy' or 'biclonal gammopathy'. A knowledge of such an unusual occurrence is essential for recognition and appropriate interpretation of this entity.
authors.affiliation: Department of Immunopathology, Level 4, Research Block A, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012 India.
authors.forename: Vishrut K
authors.initials: VK
authors.lastname: Srinivasan
authors.affiliation: Department of Immunopathology, Level 4, Research Block A, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012 India.
authors.forename: Priyanka
authors.initials: P
authors.lastname: Bhagat
authors.affiliation: Department of Immunopathology, Level 4, Research Block A, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012 India.
authors.forename: Frainey
authors.initials: F
authors.lastname: Bansal
authors.affiliation: Department of Immunopathology, Level 4, Research Block A, Postgraduate Institute of Medical Education and Research, Sector-12, Chandigarh, 160012 India.
authors.forename: Seema
authors.initials: S
authors.lastname: Chhabra
keywords: Biclonal; Double gammopathy; Monoclonal gammopathy; Monoclonal proteins