title: Circular Helix-Like Curve: An Effective Tool of Biological Sequence Analysis and Comparison.
abstract: This paper constructed a novel injection from a DNA sequence to a 3D graph, named circular helix-like curve (CHC). The presented graphical representation is available for visualizing characterizations of a single DNA sequence and identifying similarities and differences among several DNAs. A 12-dimensional vector extracted from CHC, as a numerical characterization of CHC, was applied to analyze phylogenetic relationships of 11 species, 74 ribosomal RNAs, 48 Hepatitis E viruses, and 18 eutherian mammals, respectively. Successful experiments illustrated that CHC is an effective tool of biological sequence analysis and comparison.
authors.affiliation: College of Science, Yanshan University, Qinhuangdao 066004, China.
authors.forename: Yushuang
authors.initials: Y
authors.lastname: Li
authors.affiliation: College of Science, Yanshan University, Qinhuangdao 066004, China.
authors.forename: Wenli
authors.identifier: 0000-0002-7326-538X
authors.initials: W
authors.lastname: Xiao
mesh_terms: D000465:Algorithms; D000818:Animals; D003196:Computer Graphics; D004247:DNA / Q000032:analysis*; D016752:Hepatitis E virus; D006801:Humans; D008962:Models, Theoretical; D009690:Nucleic Acid Conformation; D010802:Phylogeny; D012335:RNA, Ribosomal / Q000032:analysis; D012367:RNA, Viral / Q000032:analysis
chemical_list: D012335:RNA, Ribosomal; D012367:RNA, Viral; D004247:DNA