title: Three new acyltyramines from Anisodus luridus Link et Otto (Solanaceae).
abstract: Three new acyltyramines, N-[2-(4-hydroxyphenyl)ethyl]hentriacontanamide (1), N-[2-(4-hydroxyphenyl)ethyl]nonacosanamide (2) and N-[2-(4-hydroxyphenyl)ethyl]heneicosanamide (3) have been isolated from n-hexane extract of leaves of Anisodus luridus (Solanaceae). Successive extraction of defatted leaves of A. luridus with methanol afforded a residue on removal of solvent under reduced pressure. Residue was partitioned by means of chloroform and n-butanol. Chromatographic resolution of n-BuOH extract afforded six known compounds, apigenin (4), luteolin (5), quercetin (6), quercetin 3-O-α-l-rhamnoside (7), kaempferol 3-O-α-rhamnoside (8) and quercetin 3-O-α-l-rhamnopyranosyl-(1→6)-β-d-glucopyranoside (9). The structures of the isolated compounds were assigned with the help of spectroscopic techniques. This is the first report of isolation of these compounds from this plant.
authors.affiliation: a Department of Medicinal Chemistry, Institute of Medical Sciences , Banaras Hindu University , Varanasi , India.
authors.forename: Lalit Kumar Lal
authors.initials: LK
authors.lastname: Das
authors.affiliation: a Department of Medicinal Chemistry, Institute of Medical Sciences , Banaras Hindu University , Varanasi , India.
authors.forename: Mradul
authors.initials: M
authors.lastname: Verma
authors.affiliation: a Department of Medicinal Chemistry, Institute of Medical Sciences , Banaras Hindu University , Varanasi , India.
authors.forename: Mahendra
authors.initials: M
authors.lastname: Sahai
mesh_terms: D047310:Apigenin / Q000302:isolation & purification; D006027:Glycosides / Q000302:isolation & purification; D044949:Kaempferols / Q000302:isolation & purification; D047311:Luteolin / Q000302:isolation & purification; D018515:Plant Leaves / Q000737:chemistry; D011794:Quercetin / Q000302:isolation & purification; D019657:Solanaceae / Q000737:chemistry*; D014439:Tyramine / Q000031:analogs & derivatives* / Q000737:chemistry / Q000302:isolation & purification / Q000494:pharmacology
chemical_list: D006027:Glycosides; D044949:Kaempferols; C000617458:N-(2-(4-hydroxyphenyl)ethyl)heneicosanamide; C000617456:N-(2-(4-hydroxyphenyl)ethyl)hentriacontanamide; C000617457:N-(2-(4-hydroxyphenyl)ethyl)nonacosanamide; C470066:kaempferol 3-O-rhamnoside; D047310:Apigenin; D011794:Quercetin; D047311:Luteolin; D014439:Tyramine
keywords: Anisodus luridus; Solanaceae; acyltyramines; leaves