title: Impact of preoperative platelet count on perioperative outcome after laparoscopic splenectomy for idiopathic thrombocytopenic purpura.
abstract: BACKGROUND
  Laparoscopic splenectomy (LS) is the preferred treatment of idiopathic thrombocytopenic purpura (ITP) when medical treatment fails. The objective was to evaluate the feasibility and safety of LS according to the preoperative platelet count.
  
  
  METHODS
  This study is a retrospective analysis of a series of 199 patients who underwent LS for ITP from 1993 to 2015. The patients were divided into 3 groups according to platelet count: group i (<10×10(9)/L), group ii (10-50×10(9)/L) and group iii (> 50×10(9)/L).
  
  
  RESULTS
  Operative time was significantly lower in Group III compared to Group I and II (100±53 and 105±61min, P<.025)). Intraoperative blood loss was statistically higher in group i (263±551ml) with respect to the other 2: group ii (128±352ml) and group iii (24±62ml) (P<.003). Hospital stay was 6.4±5.8 days in group i, significantly higher compared to groups ii and iii (3.8±2.3 and 3.2±1.8 days, respectively (P<.003)).
  
  
  CONCLUSIONS
  Conducting a LS in ITP patients with low platelet counts is effective and safe.
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España. Electronic address: belen_marar@hotmail.com.
authors.forename: Belén
authors.initials: B
authors.lastname: Martin Arnau
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: Víctor
authors.initials: V
authors.lastname: Turrado Rodriguez
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: Ernesto
authors.initials: E
authors.lastname: Tartaglia
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: Jesús
authors.initials: J
authors.lastname: Bollo Rodriguez
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: Eduardo M
authors.initials: EM
authors.lastname: Targarona
authors.affiliation: Servicio de Cirugía General y Aparato Digestivo, Hospital Santa Creu i Sant Pau, Universidad Autónoma de Barcelona, Barcelona, España.
authors.forename: Manuel
authors.initials: M
authors.lastname: Trias Folch
mesh_terms: D000328:Adult; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D010535:Laparoscopy; D008297:Male; D008875:Middle Aged; D010976:Platelet Count; D057234:Preoperative Period; D016553:Purpura, Thrombocytopenic, Idiopathic / Q000097:blood* / Q000601:surgery*; D012189:Retrospective Studies; D013156:Splenectomy / Q000379:methods*; D016896:Treatment Outcome
keywords: Esplenectomía laparoscópica; Idiopathic thrombocytopenic purpura; Laparoscopic splenectomy; Púrpura trombocitopénica idiopática; Severe thrombocytopenia; Trombocitopenia severa