title: Phthalate metabolites in the European eel (Anguilla anguilla) from Mediterranean coastal lagoons.
abstract: The levels and fate of phthalate metabolites have been poorly evaluated in fish, despite their potential ecotoxicological impacts. The present study aims to characterize the levels of phthalate metabolites in muscle tissue of yellow eels (Anguilla anguilla) from two coastal Mediterranean lagoons, during three sampling periods. Nine phthalate metabolites were detected in >70% of the samples. Slightly higher levels of phthalate metabolites were detected in March and June compared to October, suggesting possible seasonal variations in environmental release and/or phthalate metabolization process by eels. The large sample size (N=117) made it possible to explore correlations between phthalate metabolites' levels and individual parameters, such as body length, age, body condition and hepatic histo-pathologies. Body length and estimated age poorly correlated with phthalate metabolites, suggesting that eels did not accumulate phthalates during growth, contrary to persistent compounds. Eels presented different grades of hepatic fibrosis and lipidosis. A negative correlation was found between the severity of these pathologies in the liver and the sum of phthalate metabolites levels, supporting the hypothesis that eels with damaged liver are less able to metabolize xenobiotics.
authors.affiliation: École Pratique des Hautes Études (EPHE), SPL, UPMC Univ Paris 06, UMR 7619 METIS, F-75005, 4 Place Jussieu, Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Fourgous
authors.affiliation: École Pratique des Hautes Études (EPHE), SPL, UPMC Univ Paris 06, UMR 7619 METIS, F-75005, 4 Place Jussieu, Paris, France.
authors.forename: M
authors.initials: M
authors.lastname: Chevreuil
authors.affiliation: École Pratique des Hautes Études (EPHE), SPL, UPMC Univ Paris 06, UMR 7619 METIS, F-75005, 4 Place Jussieu, Paris, France.
authors.forename: F
authors.initials: F
authors.lastname: Alliot
authors.affiliation: Univ. Perpignan Via Domitia, Centre de Formation et de Recherche sur les Environnements Méditerranéens, UMR 5110, F-66860 Perpignan, France; CNRS, CEntre de Formation et de Recherche sur les Environnements Méditerranéens, UMR 5110, F-66860 Perpignan, France.
authors.forename: E
authors.initials: E
authors.lastname: Amilhat
authors.affiliation: Univ. Perpignan Via Domitia, Centre de Formation et de Recherche sur les Environnements Méditerranéens, UMR 5110, F-66860 Perpignan, France; CNRS, CEntre de Formation et de Recherche sur les Environnements Méditerranéens, UMR 5110, F-66860 Perpignan, France.
authors.forename: E
authors.initials: E
authors.lastname: Faliex
authors.affiliation: Université de Reims Champagne Ardenne, UMR-I 02, Stress Environnementaux et BIOsurveillance des milieux aquatiques (SEBIO), CNRS, Reims, France.
authors.forename: S
authors.initials: S
authors.lastname: Paris-Palacios
authors.affiliation: École Pratique des Hautes Études (EPHE), SPL, UPMC Univ Paris 06, UMR 7619 METIS, F-75005, 4 Place Jussieu, Paris, France.
authors.forename: M J
authors.initials: MJ
authors.lastname: Teil
authors.affiliation: École Pratique des Hautes Études (EPHE), SPL, UPMC Univ Paris 06, UMR 7619 METIS, F-75005, 4 Place Jussieu, Paris, France. Electronic address: aurelie.goutte@ephe.sorbonne.fr.
authors.forename: A
authors.initials: A
authors.lastname: Goutte
mesh_terms: D000367:Age Factors; D000811:Anguilla / Q000378:metabolism*; D000818:Animals; D049628:Body Size; D005602:France; D008099:Liver / Q000737:chemistry; D009132:Muscles / Q000737:chemistry; D010795:Phthalic Acids / Q000378:metabolism*; D014874:Water Pollutants, Chemical / Q000378:metabolism*
chemical_list: D010795:Phthalic Acids; D014874:Water Pollutants, Chemical; C032279:phthalic acid
keywords: By-product; Fish; Phthalate monoesters; Plasticizers