title: Isolated splenic metastasis from a thymic carcinoma: A case report.
abstract: Thymic carcinomas are rare tumors that arise in the anterior mediastinum. Most of these malignancies develop local metastases limited in the thorax. Splenic metastases from thymic carcinomas are extremely rare. Here we report a case of isolated splenic metastasis from a 38-year-old female patient with Stage IV thymic carcinoma, who was treated with chemoradiotherapy. At twenty-2 months follow-up, the patient was found to have an isolated spleen metastasis, which was treated by Cyberknife with a reduced size of the metastasis, representing a partial response. Although splenic metastasis is a rare phenomenon, physicians need to be aware of the possibility of such metastases.
authors.affiliation: a Department of Radiation Oncology , Hospital of PLA, Clinical College, Anhui Medical University , Beijing , P.R. China.|b Department of Radiation Oncology , Affiliated Hospital of Academy of Military Medical Sciences , Beijing , P.R. China.
authors.forename: Dongmei
authors.initials: D
authors.lastname: Chen
authors.affiliation: b Department of Radiation Oncology , Affiliated Hospital of Academy of Military Medical Sciences , Beijing , P.R. China.
authors.forename: Xiangying
authors.initials: X
authors.lastname: Meng
authors.affiliation: b Department of Radiation Oncology , Affiliated Hospital of Academy of Military Medical Sciences , Beijing , P.R. China.
authors.forename: Yaowei
authors.initials: Y
authors.lastname: Zhao
authors.affiliation: a Department of Radiation Oncology , Hospital of PLA, Clinical College, Anhui Medical University , Beijing , P.R. China.|b Department of Radiation Oncology , Affiliated Hospital of Academy of Military Medical Sciences , Beijing , P.R. China.
authors.forename: Shikai
authors.initials: S
authors.lastname: Wu
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D009362:Neoplasm Metastasis; D013160:Splenic Neoplasms / Q000473:pathology / Q000556:secondary* / Q000628:therapy; D013945:Thymoma / Q000473:pathology*; D013953:Thymus Neoplasms / Q000473:pathology*
keywords: Chemotherapy; PET/CT; SBRT; oligometastasis; radiation; spleen metastasis; thymic carcinoma