title: Glycerolipid synthesis and lipid trafficking in plant mitochondria.
abstract: Lipid trafficking between mitochondria and other organelles is required for mitochondrial membrane biogenesis and signaling. This lipid exchange occurs by poorly understood nonvesicular mechanisms. In yeast and mammalian cells, this lipid exchange is thought to take place at contact sites between mitochondria and the ER or vacuolar membranes. Some proteins involved in the tethering between membranes or in the transfer of lipids in mitochondria have been identified. However, in plants, little is known about the synthesis of mitochondrial membranes. Mitochondrial membrane biogenesis is particularly important and noteworthy in plants as the lipid composition of mitochondrial membranes is dramatically changed during phosphate starvation and other stresses. This review focuses on the principal pathways involved in the synthesis of the most abundant mitochondrial glycerolipids in plants and the lipid trafficking that is required for plant mitochondria membrane biogenesis.
authors.affiliation: Laboratory of Cell and Molecular Biology, National Institutes of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA.|Laboratoire de Physiologie Cellulaire et Végétale, UMR 5168 CNRS-CEA-INRA-Université Grenoble Alpes, Grenoble, France.
authors.forename: Morgane
authors.initials: M
authors.lastname: Michaud
authors.affiliation: Laboratory of Cell and Molecular Biology, National Institutes of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA.
authors.forename: William A
authors.initials: WA
authors.lastname: Prinz
authors.affiliation: Laboratoire de Physiologie Cellulaire et Végétale, UMR 5168 CNRS-CEA-INRA-Université Grenoble Alpes, Grenoble, France.
authors.forename: Juliette
authors.initials: J
authors.lastname: Jouhet
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000378:metabolism*; D001692:Biological Transport; D004721:Endoplasmic Reticulum / Q000737:chemistry / Q000378:metabolism; D015870:Gene Expression; D006017:Glycolipids / Q000096:biosynthesis* / Q000737:chemistry; D050356:Lipid Metabolism; D008928:Mitochondria / Q000737:chemistry / Q000378:metabolism*; D051336:Mitochondrial Membranes / Q000737:chemistry / Q000378:metabolism*; D024101:Mitochondrial Proteins / Q000235:genetics / Q000378:metabolism*; D001678:Organelle Biogenesis; D018087:Plastids / Q000737:chemistry / Q000378:metabolism; D014617:Vacuoles / Q000737:chemistry / Q000378:metabolism
chemical_list: D006017:Glycolipids; D024101:Mitochondrial Proteins; C015903:glycerolglycolipids
keywords: lipid trafficking; membrane biogenesis; membrane contact sites; mitochondria; phosphate starvation; plants