title: Thrombolytic treatment in a patient with antiphospholipid syndrome : APS developing renal infarction.
abstract: Antiphospholipid syndrome (APS), a leading entity in acquired thrombophilia, is characterized by recurrent thrombosis, morbidity in pregnancy and presence of antiphospholipid antibodies (APA). Although the etiopathogenesis is unclear, APA against negatively charged phospholipids and phospholipid-protein complexes are held responsible for the clinical picture. In case of acute thrombosis due to APS, thrombolytic therapy is not a commonly administered treatment option. Here, we present a case with acute thrombosis in the left renal artery showing partial response to thrombolytic therapy.
authors.affiliation: Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University, Ayazmana Mah., 4419. Cad. Metro City Vadi Evleri D Blok Daire: 16, 32000, Isparta, Turkey. dryunusugan@hotmail.com.
authors.forename: Y
authors.initials: Y
authors.lastname: Ugan
authors.affiliation: Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University, Ayazmana Mah., 4419. Cad. Metro City Vadi Evleri D Blok Daire: 16, 32000, Isparta, Turkey.
authors.forename: A
authors.initials: A
authors.lastname: Dogru
authors.affiliation: Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University, Ayazmana Mah., 4419. Cad. Metro City Vadi Evleri D Blok Daire: 16, 32000, Isparta, Turkey.
authors.forename: M
authors.initials: M
authors.lastname: Sahin
authors.affiliation: Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Suleyman Demirel University, Ayazmana Mah., 4419. Cad. Metro City Vadi Evleri D Blok Daire: 16, 32000, Isparta, Turkey.
authors.forename: S E
authors.initials: SE
authors.lastname: Tunc
mesh_terms: D000328:Adult; D016736:Antiphospholipid Syndrome / Q000150:complications* / Q000175:diagnosis / Q000188:drug therapy*; D003937:Diagnosis, Differential; D005260:Female; D005343:Fibrinolytic Agents / Q000008:administration & dosage*; D006801:Humans; D007238:Infarction / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control*; D007668:Kidney / Q000098:blood supply*; D016896:Treatment Outcome
chemical_list: D005343:Fibrinolytic Agents
keywords: Antiphospholipid syndrome; Renal infarction; Thrombolytic treatment