title: A survey of medical image registration - under review.
abstract: A retrospective view on the past two decades of the field of medical image registration is presented, guided by the article "A survey of medical image registration" (Maintz and Viergever, 1998). It shows that the classification of the field introduced in that article is still usable, although some modifications to do justice to advances in the field would be due. The main changes over the last twenty years are the shift from extrinsic to intrinsic registration, the primacy of intensity-based registration, the breakthrough of nonlinear registration, the progress of inter-subject registration, and the availability of generic image registration software packages. Two problems that were called urgent already 20 years ago, are even more urgent nowadays: Validation of registration methods, and translation of results of image registration research to clinical practice. It may be concluded that the field of medical image registration has evolved, but still is in need of further development in various aspects.
authors.affiliation: Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: max@isi.uu.nl.
authors.forename: Max A
authors.initials: MA
authors.lastname: Viergever
authors.affiliation: Faculty of Science, Utrecht University, Utrecht, The Netherlands. Electronic address: j.b.a.maintz@uu.nl.
authors.forename: J B Antoine
authors.initials: JBA
authors.lastname: Maintz
authors.affiliation: Biomedical Imaging Group Rotterdam, Departments of Medical Informatics and Radiology, Erasmus MC, Rotterdam, The Netherlands. Electronic address: s.klein@erasmusmc.nl.
authors.forename: Stefan
authors.initials: S
authors.lastname: Klein
authors.affiliation: INFANT Research Centre, University College Cork, Cork, Ireland. Electronic address: keelinm@gmail.com.
authors.forename: Keelin
authors.initials: K
authors.lastname: Murphy
authors.affiliation: Division of Image Processing, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: m.staring@lumc.nl.
authors.forename: Marius
authors.initials: M
authors.lastname: Staring
authors.affiliation: Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, The Netherlands; Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands. Electronic address: j.pluim@tue.nl.
authors.forename: Josien P W
authors.initials: JPW
authors.lastname: Pluim
mesh_terms: D000465:Algorithms; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000639:trends; D012189:Retrospective Studies
keywords: Medical image registration