title: Gallstones and Bariatric Surgery: To Treat or Not to Treat?
abstract: Obesity and rapid weight loss after bariatric surgery are risk factors for gallstone disease.
  
  
  
  The present study sought to evaluate the feasibility of selective concomitant cholecystectomy only in patients with symptomatic disease and study risk factors for the development of symptomatic gallstones after bariatric surgery.
  
  
  
  Between January 2010 and December 2012, 734 consecutive patients presenting to our institution underwent bariatric surgery. From these, 81 patients were excluded due to prior or concurrent cholecystectomy. The remaining 653 patients with in situ gallbladder were followed for 12 months and were clinically screened for symptomatic or complicated cholelithiasis. Clinical and demographic characteristics were compared at baseline and 12 months after surgery.
  
  
  
  Of the 653 patients with in situ gallbladder, only 24 (3.3 %) developed symptomatic gallstones and only nine presented complicated disease. None of the patients with asymptomatic disease at the time of surgery progressed to symptomatic or complicated disease. Patients who developed symptomatic disease were not significantly different, although there was a trend toward longer obesity evolution, lower insulin levels, and lower hepatic enzymes level. A multivariate regression analysis revealed that patients with gastric sleeve were more likely to develop symptomatic gallstones.
  
  
  
  Although further studies are required, the management of gallstones in morbidly obese patients should not be different from normal-weight patients. Therefore, performing a laparoscopic cholecystectomy only in symptomatic patients is an effective approach and asymptomatic gallstones should not be treated at the time of bariatric surgery.
authors.affiliation: General Surgery Department, Sao Joao Medical Center, Porto, Portugal. morais1000@gmail.com.
authors.forename: Marina
authors.initials: M
authors.lastname: Morais
authors.affiliation: Center for Health Technology and Services Research (CINTESIS), Instituto de Ciências Biomédicas de Abel Salazar, Porto, Portugal.
authors.forename: Gil
authors.initials: G
authors.lastname: Faria
authors.affiliation: General Surgery Department, Sao Joao Medical Center, Porto, Portugal.
authors.forename: John
authors.initials: J
authors.lastname: Preto
authors.affiliation: General Surgery Department, Sao Joao Medical Center, Porto, Portugal.
authors.forename: José
authors.initials: J
authors.lastname: Costa-Maia
mesh_terms: D000328:Adult; D050110:Bariatric Surgery / Q000379:methods*; D017081:Cholecystectomy, Laparoscopic; D005260:Female; D005500:Follow-Up Studies; D042882:Gallstones / Q000175:diagnosis* / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009767:Obesity, Morbid / Q000601:surgery; D012307:Risk Factors; D063189:Symptom Assessment