title: Postnatal Stress in Mice: Effects on Body Fat, Plasma Lipids, Glucose and Insulin.
abstract: Mice pups were exposed to stressful stimuli everyday during the first 3 weeks of life. Body weight, food intake and spontaneous locomotor activity, triglycerides, cholesterol, phospholipids, glucose and insulin basal levels, as well as epididymal fat pad weight and its cell volume were measured in stressed and control animals. Results indicated that postnatal stressful manipulations induced an increase in body weight, epididymal fat pad weight and its cell volume, as well as in insulin, glucose, cholesterol and triglycerides plasma levels, at 4 months of age. No significant changes in food consumption, locomotor activity and phospholipids plasma levels were found. Present data suggest that early stressful manipulations may induce residual effects on lipid and glucid metabolism.
authors.affiliation: a Laboratorio di Alimenti , Istituto Superiore di Sanità , Viale Regina Elena 299, 00161 Rome , Italy.
authors.forename: A
authors.initials: A
authors.lastname: d'Amore
authors.affiliation: b Laboratorio di Biochimica Clinica , Istituto Superiore di Sanità , Viale Regina Elena 299, 00161 Rome , Italy.
authors.forename: S
authors.initials: S
authors.lastname: Caiola
authors.affiliation: b Laboratorio di Biochimica Clinica , Istituto Superiore di Sanità , Viale Regina Elena 299, 00161 Rome , Italy.
authors.forename: E
authors.initials: E
authors.lastname: Maroccia
authors.affiliation: c Laboratorio di Farmacologia , Istituto Superiore di Sanità , Viale Regina Elena 299, 00161 Rome , Italy.
authors.forename: A
authors.initials: A
authors.lastname: Loizzo
keywords: Development; Epididymal fat; Food intake; Glucids; Lipids; Locomotor activity; Metabolism; Mouse; Stress