title: Inflammatory bowel disease related innate immunity and adaptive immunity.
abstract: Inflammatory bowel disease (IBD) is a chronic nonspecific intestinal inflammatory disease, including ulcerative colitis (UC) and Crohn's disease (CD). Its pathogenesis remains not yet clear. Current researchers believe that after environmental factors act on individuals with genetic susceptibility, an abnormal intestinal immune response is launched under stimulation of intestinal flora. However, previous studies only focused on adaptive immunity in the pathogenesis of IBD. Currently, roles of innate immune response in the pathogenesis of intestinal inflammation have also drawn much attention. In this study, IBD related innate immunity and adaptive immunity were explained, especially the immune mechanisms in the pathogenesis of IBD.
authors.affiliation: Center for Hepatobiliary and Pancreatic Diseases, Beijing Tsinghua Changgung Hospital, Medical Center, Tsinghua University China.
authors.forename: Yuan
authors.initials: Y
authors.lastname: Huang
authors.affiliation: Department of Gastroenterology, Second Affiliated Hospital of Nanchang University Nanchang, China.
authors.forename: Zhonge
authors.initials: Z
authors.lastname: Chen
keywords: Inflammatory bowel disease; adaptive immunity; innate immunity; pathogenesis