title: New preclinical data - the case for Ialuril®.
abstract: This article briefly summarises data published over the last decade which have investigated the concept that intravesical instillation of glycosaminoglycans (GAGs) hyaluronic acid and chondroitin sulfate is able to restore the GAG layer and provide a beneficial effect in protecting the bladder. In the second half of this article, pre-clinical studies which assess the effectiveness of intravesical instillation of Ialuril® after chemical or electromechanical damage to the rat bladder wall are described.
authors.affiliation: Department of Urology, Università Vita-Salute San Raffaele, URI-Urological Research Institute, IRCCS Ospedale San Raffaele, Milan - Italy.
authors.forename: Andrea
authors.initials: A
authors.lastname: Salonia
mesh_terms: D000283:Administration, Intravesical; D000818:Animals; D002809:Chondroitin Sulfates / Q000008:administration & dosage / Q000494:pharmacology*; D004338:Drug Combinations; D006025:Glycosaminoglycans; D006820:Hyaluronic Acid / Q000008:administration & dosage / Q000494:pharmacology*; D051381:Rats; D001743:Urinary Bladder / Q000187:drug effects*
chemical_list: D004338:Drug Combinations; D006025:Glycosaminoglycans; C501944:chondroitin sulfate, sodium hyaluronate drug combination; D006820:Hyaluronic Acid; D002809:Chondroitin Sulfates