title: RIPK3 Slams the Brake on Leukemogenesis.
abstract: Evasion of cell death is a key hallmark of cancers. In this issue of Cancer Cell, Höckendorf and colleagues identified RIPK3, an essential kinase for necroptosis, as having a key role in inhibiting acute myeloid leukemia development.
authors.affiliation: Department of Pathology, Immunology and Microbiology Program, University of Massachusetts Medical School, 368 Plantation Street, Worcester, MA 01605, USA. Electronic address: francis.chan@umassmed.edu.
authors.forename: Francis Ka-Ming
authors.initials: FK
authors.lastname: Chan
mesh_terms: D017209:Apoptosis / Q000187:drug effects*; D016923:Cell Death / Q000187:drug effects; D006801:Humans; D007938:Leukemia; D009336:Necrosis; D014409:Tumor Necrosis Factor-alpha / Q000494:pharmacology
chemical_list: D014409:Tumor Necrosis Factor-alpha