title: Electrical Chips for Biological Point-of-Care Detection.
abstract: As the future of health care diagnostics moves toward more portable and personalized techniques, there is immense potential to harness the power of electrical signals for biological sensing and diagnostic applications at the point of care. Electrical biochips can be used to both manipulate and sense biological entities, as they can have several inherent advantages, including on-chip sample preparation, label-free detection, reduced cost and complexity, decreased sample volumes, increased portability, and large-scale multiplexing. The advantages of fully integrated electrical biochip platforms are particularly attractive for point-of-care systems. This review summarizes these electrical lab-on-a-chip technologies and highlights opportunities to accelerate the transition from academic publications to commercial success.
authors.affiliation: Department of Electrical and Computer Engineering.|Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801; email: rbashir@illinois.edu.
authors.forename: Bobby
authors.initials: B
authors.lastname: Reddy
authors.affiliation: Department of Bioengineering, and.|Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801; email: rbashir@illinois.edu.
authors.forename: Eric
authors.initials: E
authors.lastname: Salm
authors.affiliation: Department of Electrical and Computer Engineering.|Department of Bioengineering, and.|Micro and Nanotechnology Laboratory, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801; email: rbashir@illinois.edu.
authors.forename: Rashid
authors.initials: R
authors.lastname: Bashir
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation* / Q000379:methods; D003217:Conductometry / Q000295:instrumentation* / Q000379:methods; D004582:Electronics, Medical / Q000295:instrumentation*; D004867:Equipment Design; D056656:Lab-On-A-Chip Devices; D000067716:Point-of-Care Testing; D018511:Systems Integration
keywords: biochip; biosensor; chips; diagnostics; electrical; label-free; microfabrication; point-of-care