title: An international randomized study of a home-based self-management program for severe COPD: the COMET.
abstract: BACKGROUND
  Most hospitalizations and costs related to COPD are due to exacerbations and insufficient disease management. The COPD patient Management European Trial (COMET) is investigating a home-based multicomponent COPD self-management program designed to reduce exacerbations and hospital admissions.
  
  
  METHODS
  Multicenter parallel randomized controlled, open-label superiority trial.
  
  
  METHODS
  Thirty-three hospitals in four European countries.
  
  
  METHODS
  A total of 345 patients with Global initiative for chronic Obstructive Lung Disease III/IV COPD.
  
  
  METHODS
  The program includes extensive patient coaching by health care professionals to improve self-management (eg, develop skills to better manage their disease), an e-health platform for reporting frequent health status updates, rapid intervention when necessary, and oxygen therapy monitoring. Comparator is the usual management as per the center's routine practice.
  
  
  METHODS
  Yearly number of hospital days for acute care, exacerbation number, quality of life, deaths, and costs.
authors.affiliation: Respiratory Epidemiology and Clinical Research Unit, Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada.
authors.forename: Jean
authors.initials: J
authors.lastname: Bourbeau
authors.affiliation: Hospital Universitario Central de Asturias, Facultad de Medicina, Oviedo, Spain.
authors.forename: Pere
authors.initials: P
authors.lastname: Casan
authors.affiliation: Lung Department, Ospedale Orlandi, Bussolengo VR, Italy.
authors.forename: Silvia
authors.initials: S
authors.lastname: Tognella
authors.affiliation: Krankenhaus Kloster Grafschaft, Schmallenberg, Germany.
authors.forename: Peter
authors.initials: P
authors.lastname: Haidl
authors.affiliation: Air Liquide Healthcare, Medical Research and Development, Jouy-en-Josas; Assistance Publique-Hôpitaux de Paris, Service de Physiologie Clinique, Hôpital Cochin, Paris.
authors.forename: Joëlle B
authors.initials: JB
authors.lastname: Texereau
authors.affiliation: Department of Pulmonary Medicine, Translational Medicine Federation of Strasbourg, University Hospital of Strasbourg, Strasbourg, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Kessler
mesh_terms: D003362:Cost-Benefit Analysis; D018450:Disease Progression; D005060:Europe; D017048:Health Care Costs; D007722:Health Knowledge, Attitudes, Practice; D018575:Home Care Services, Hospital-Based / Q000191:economics; D006760:Hospitalization; D006801:Humans; D007902:Length of Stay; D008168:Lung / Q000503:physiopathology*; D010102:Oxygen Inhalation Therapy; D010349:Patient Compliance; D010353:Patient Education as Topic; D029424:Pulmonary Disease, Chronic Obstructive / Q000191:economics / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D011788:Quality of Life; D012648:Self Care / Q000191:economics / Q000379:methods*; D012720:Severity of Illness Index; D017216:Telemedicine; D013997:Time Factors; D016896:Treatment Outcome
keywords: COPD; clinical trial; disease management; exacerbations; home care; hospitalization