title: Two new 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives from Craterellus odoratus.
abstract: Two rare types of 4,6-dimethyl-3,4-dihydrochromen-2-one derivatives, named cralactones A and B (1 and 2), were isolated from the culture broth of Craterellus odoratus. The structures of the new ones were established on the basis of extensive spectroscopic analysis, and it was found that the new compounds did not show pancreatic lipase inhibitory activity. Compounds 1 and 2 are the first examples of 4,6-dimethyl-3,4-dihydrochromen-2-one.
authors.affiliation: a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Ling
authors.initials: L
authors.lastname: Zhang
authors.affiliation: a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.|b University of Chinese Academy of Sciences , Beijing 100049 , China.
authors.forename: Jian-Neng
authors.initials: JN
authors.lastname: Yao
authors.affiliation: a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Xue
authors.initials: X
authors.lastname: Bai
authors.affiliation: c School of Pharmaceutical Sciences , South-Central University for Nationalities , Wuhan 430074 , China.
authors.forename: Zheng-Hui
authors.initials: ZH
authors.lastname: Li
authors.affiliation: a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.
authors.forename: Ze-Jun
authors.initials: ZJ
authors.lastname: Dong
authors.affiliation: a State Key Laboratory of Phytochemistry and Plant Resources in West China , Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201 , China.|c School of Pharmaceutical Sciences , South-Central University for Nationalities , Wuhan 430074 , China.
authors.forename: Ji-Kai
authors.initials: JK
authors.lastname: Liu
mesh_terms: D001487:Basidiomycota / Q000737:chemistry*; D002867:Chromones / Q000737:chemistry / Q000302:isolation & purification* / Q000494:pharmacology; D008049:Lipase / Q000037:antagonists & inhibitors*; D015394:Molecular Structure; D010179:Pancreas / Q000201:enzymology
chemical_list: D002867:Chromones; C000616375:cralactone A; C000616376:cralactone B; D008049:Lipase
keywords: 4,6-dimethyl-3,4-dihydrochromen-2-one; Craterellus odoratus; cralactone; pancreatic lipase