title: A Mesoporous Indium Metal-Organic Framework: Remarkable Advances in Catalytic Activity for Strecker Reaction of Ketones.
abstract: With the aim of developing new highly porous, heterogeneous Lewis acid catalysts for multicomponent reactions, a new mesoporous metal-organic framework, InPF-110 ([In3O(btb)2(HCOO)(L)], (H3btb = 1,3,5-tris(4-carboxyphenyl)benzene acid, L = methanol, water, or ethanol), has been prepared with indium as the metal center. It exhibits a Langmuir surface area of 1470 m(2) g(-1), and its structure consists of hexagonal pores with a 2.8 nm aperture, which allows the diffusion of multiple substrates. This material presents a large density of active metal sites resulting in outstanding catalytic activity in the formation of substituted α-aminonitriles through the one-pot Strecker reaction of ketones. In this respect, InPF-110 stands out compared to other catalysts for this reaction due to the small catalyst loadings required, and without the need for heat or solvents. Furthermore, X-ray single crystal diffraction studies clearly show the framework-substrate interaction through coordination to the accessible indium sites.
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: Daniel
authors.initials: D
authors.lastname: Reinares-Fisac
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: Lina María
authors.initials: LM
authors.lastname: Aguirre-Díaz
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: Marta
authors.initials: M
authors.lastname: Iglesias
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: Natalia
authors.initials: N
authors.lastname: Snejko
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: Enrique
authors.initials: E
authors.lastname: Gutiérrez-Puebla
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: M Ángeles
authors.initials: MÁ
authors.lastname: Monge
authors.affiliation: Departamento de Nuevas Arquitecturas en Química de Materiales - Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC) , Sor Juana Inés de la Cruz 3, Cantoblanco 28049, Madrid, Spain.
authors.forename: Felipe
authors.initials: F
authors.lastname: Gándara