title: Stressed telomeres without POT1 enhance tumorigenesis.
authors.affiliation: Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
authors.forename: Agnel
authors.initials: A
authors.lastname: Sfeir
authors.affiliation: Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA.
authors.forename: Eros Lazzerini
authors.initials: EL
authors.lastname: Denchi
mesh_terms: D000818:Animals; D063646:Carcinogenesis / Q000235:genetics*; D004261:DNA Replication; D004268:DNA-Binding Proteins / Q000172:deficiency* / Q000235:genetics / Q000378:metabolism; D051379:Mice; D009154:Mutation; D009369:Neoplasms / Q000235:genetics* / Q000378:metabolism / Q000473:pathology*; D000089804:Shelterin Complex; D016615:Telomere / Q000235:genetics / Q000378:metabolism* / Q000473:pathology*; D034501:Telomere-Binding Proteins
chemical_list: D004268:DNA-Binding Proteins; C507326:POT1 protein, mouse; D000089804:Shelterin Complex; D034501:Telomere-Binding Proteins
keywords: POT1; genomic stability; telomere; replication stress; ATR; Autophagy