title: Psoriasis and Psoriatic Arthritis-Related Uveitis: Different Ophthalmological Manifestations and Ocular Inflammation Features.
abstract: OBJECTIVE
  To compare clinical features of uveitis in patients affected by psoriasis and psoriatic arthritis (PsA).
  
  
  METHODS
  A retrospective case-control study.
  
  
  RESULTS
  117 patients were affected by uveitis and psoriasis or PsA (92 and 25 patients, respectively) from 2003 to 2013. Axial PsA was associated with unilateral uveitis onset compared to the peripheral pattern (p < 0.03). The prevalence of eyes with at least one complication involving anterior segment was significantly more represented in the PsA group than the psoriasis one (p = 0.024). Anterior segment complications were more frequently associated with posterior ones in PsA patients than in psoriasis patients (p = 0.005). Most common complications in total sample at baseline examination were cataract (29.7%), ocular hypertension (17%), macular edema (7%), and pupillary seclusion (4.4%).
  
  
  CONCLUSIONS
  Uveitis in patients with psoriasis and PsA may have distinguishing clinical features. PsA patients have more ocular complications than those with psoriasis. Both groups need an ophthalmological examination to promptly detect ocular co-morbidity.
authors.affiliation: a Department of Ophthalmology , Sapienza University of Rome , Rome , Italy.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Abbouda
authors.affiliation: a Department of Ophthalmology , Sapienza University of Rome , Rome , Italy.
authors.forename: Irene
authors.initials: I
authors.lastname: Abicca
authors.affiliation: a Department of Ophthalmology , Sapienza University of Rome , Rome , Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Fabiani
authors.affiliation: a Department of Ophthalmology , Sapienza University of Rome , Rome , Italy.
authors.forename: Nicolò
authors.initials: N
authors.lastname: Scappatura
authors.affiliation: b Department of Ophthalmology , University of Castilla la Mancha , Albacete , Spain.
authors.forename: Pablo
authors.initials: P
authors.lastname: Peña-García
authors.affiliation: c Rheumatology Unit , Sapienza University of Rome , Rome , Italy.
authors.forename: Rossana
authors.initials: R
authors.lastname: Scrivo
authors.affiliation: c Rheumatology Unit , Sapienza University of Rome , Rome , Italy.
authors.forename: Roberta
authors.initials: R
authors.lastname: Priori
authors.affiliation: a Department of Ophthalmology , Sapienza University of Rome , Rome , Italy.
authors.forename: Maria Pia
authors.initials: MP
authors.lastname: Paroli
mesh_terms: D000328:Adult; D000368:Aged; D015535:Arthritis, Psoriatic / Q000150:complications*; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008269:Macular Edema / Q000209:etiology; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000209:etiology; D015995:Prevalence; D011565:Psoriasis / Q000150:complications*; D011681:Pupil Disorders / Q000209:etiology / Q000473:pathology; D012189:Retrospective Studies; D014605:Uveitis / Q000209:etiology / Q000473:pathology / Q000503:physiopathology
keywords: Blepharitis; cataract; dry eye; elevated intraocular pressure; episcleritis; psoriasis; psoriatic arthritis; uveitis; vitritis