title: DNA-fueled molecular machine for label-free and non-enzymatic ultrasensitive detection of telomerase activity.
abstract: Herein, a non-enzymatic and label-free strategy based on DNA-fueled molecular machine was developed for ultrasensitive detection of telomerase activity in cancer cell extracts even at the single-cell level.
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing 100039, China.
authors.forename: Panpan
authors.initials: P
authors.lastname: Sun
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing 100039, China.
authors.forename: Xiang
authors.initials: X
authors.lastname: Ran
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn and University of Chinese Academy of Sciences, Beijing 100039, China.
authors.forename: Chaoqun
authors.initials: C
authors.lastname: Liu
authors.affiliation: Department of Respiratory Medicine, The First Hospital of Jilin University, Changchun, China.
authors.forename: Chaoying
authors.initials: C
authors.lastname: Liu
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn.
authors.forename: Fang
authors.initials: F
authors.lastname: Pu
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn.
authors.forename: Jinsong
authors.initials: J
authors.lastname: Ren
authors.affiliation: Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, China. jren@ciac.ac.cn.
authors.forename: Xiaogang
authors.initials: X
authors.lastname: Qu
mesh_terms: D015374:Biosensing Techniques; D045744:Cell Line, Tumor; D004247:DNA; D006801:Humans; D019098:Telomerase / Q000032:analysis*
chemical_list: D004247:DNA; D019098:Telomerase