title: (18)F-FDG PET/CT in Neurolymphomatosis: Report of 3 Cases.
abstract: Neurolymphomatosis is a rare manifestation of non-Hodgkin lymphoma characterized by infiltration of peripheral nerves, nerve roots, plexus and cranial nerves by malignant lymphocytes. This report presents positron emission tomography/computed tomography (PET/CT)imaging with 2-deoxy-2-(18)F-fluoro-D-glucose ((18)F-FDG) in 3 cases of non-Hodgkin lymphoma with nerve infiltration, including one newly diagnosed lymphoma, one recurrent lymphoma in previous nerve lesions and one newly recurrent lymphoma. PET/CT could reveal the affected neural structures including cranial nerves, spinal nerve roots, brachial plexus, cervicothoracic ganglion, intercostal nerves, branches of the vagus nerve, lumbosacral plexus and sciatic nerves. There was relative concordance between PET/CT and MRI in detection of affected cranial nerves. PET/CT seemed to be better than MRI in detection of affected peripheral nerves. (18)F-FDG PET/CT was a whole-body imaging technique with the ability to reveal the affected cranial nerves, peripheral nerves, nerve roots and plexus in non-Hodgkin lymphoma. A thorough understanding of disease and use of advanced imaging modalities will increasingly detect neurolymphomatosis.
authors.affiliation: Unit of PET/CT and Cyclotron, Choray Hospital, Hochiminh City, Vietnam.
authors.forename: Nguyen Xuan
authors.initials: NX
authors.lastname: Canh
authors.affiliation: Unit of PET/CT and Cyclotron, Choray Hospital, Hochiminh City, Vietnam.
authors.forename: Ngo Van
authors.initials: NV
authors.lastname: Tan
authors.affiliation: Department of Hematology, Choray Hospital, Hochiminh City, Vietnam.
authors.forename: Tran Thanh
authors.initials: TT
authors.lastname: Tung
authors.affiliation: Department of Hematology, Choray Hospital, Hochiminh City, Vietnam.
authors.forename: Nguyen Truong
authors.initials: NT
authors.lastname: Son
authors.affiliation: Dipartimento Di Scienze Biomediche Avanzate, Facoltá Di Medicina E Chirurgia, Università Degli Studi Di Napoli Federico II, Italia.
authors.forename: Simone
authors.initials: S
authors.lastname: Maurea
keywords: 18F-FDG; Nerve; Neurolymphomatosis; PET/CT; Plexus