title: Boronate Affinity-Molecularly Imprinted Biocompatible Probe: An Alternative for Specific Glucose Monitoring.
abstract: A biocompatible probe for specific glucose recognition is based on photoinitiated boronate affinity-molecular imprinted polymers (BA-MIPs). The unique pre-self-assembly between glucose and boronic acids creates glucose-specific memory cavities in the BA-MIPs coating. As a result, the binding constant toward glucose was enhanced by three orders of magnitude. The BA-MIPs probe was applied to glucose determination in serum and urine and implanted into plant tissues for low-destructive and long-term in vivo continuous glucose monitoring.
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Guosheng
authors.initials: G
authors.lastname: Chen
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Junlang
authors.initials: J
authors.lastname: Qiu
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Xu'an
authors.initials: X
authors.lastname: Fang
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Jianqiao
authors.initials: J
authors.lastname: Xu
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Siying
authors.initials: S
authors.lastname: Cai
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Qing
authors.initials: Q
authors.lastname: Chen
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Liu
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China. ceszhuf@mail.sysu.edu.cn.
authors.forename: Fang
authors.initials: F
authors.lastname: Zhu
authors.affiliation: MOE Key Laboratory of Aquatic Product Safety/KLGHEI of Environment and Energy Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, 135 West Xingang Road Guangzhou, 510275, China. cesoygf@mail.sysu.edu.cn.
authors.forename: Gangfeng
authors.identifier: http://orcid.org/0000-0002-0797-6036
authors.initials: G
authors.lastname: Ouyang
mesh_terms: D001672:Biocompatible Materials / Q000737:chemistry*; D001897:Boronic Acids / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D054802:Molecular Imprinting; D015335:Molecular Probes / Q000737:chemistry*; D015394:Molecular Structure; D010316:Particle Size; D011108:Polymers / Q000737:chemistry; D013499:Surface Properties
chemical_list: D001672:Biocompatible Materials; D001897:Boronic Acids; D015335:Molecular Probes; D011108:Polymers; D005947:Glucose
keywords: biosensors; boronate affinity; glucose; molecular imprinting; self-assembly