title: Impaired colour vision in workers exposed to organic solvents: A systematic review.
abstract: OBJECTIVE
  To evaluate recent evidence concerning the relationship between the exposure to organic solvents and the impairment of colour vision.
  
  
  METHODS
  A bibliographic search was conducted for scientific papers published in the last 15 years, in the LILACS, PubMed, Science Direct, EBSCO, and Cochrane databases that included observational studies assessing the relationship between impairment in colour vision and exposure to organic solvents.
  
  
  RESULTS
  Eleven studies were selected that were performed on an economically active population and used the Lanthony D-15 desaturated test (D-15d), measured the exposure to organic solvents, and included unexposed controls. It was found that there is a statistically significant relationship between the exposure to organic solvents and the presence of an impairment in colour vision.
  
  
  CONCLUSIONS
  The results support the hypothesis that exposure to organic solvents could induce acquired dyschromatopsia. The evaluation of colour vision with the D-15d test is simple and sensitive for diagnosis. More studies need to be conducted on this subject in order to better understand the relationship between impaired colour vision and more severe side effects caused by this exposure.
authors.affiliation: Grupo de Investigación Observatorio de la Salud Pública, Universidad CES, Medellín, Colombia. Electronic address: anbetancurs@uces.edu.co.
authors.forename: A M
authors.initials: AM
authors.lastname: Betancur-Sánchez
authors.affiliation: Departamento de Epidemiología, Grupo de Investigación Observatorio de la Salud Pública, Universidad CES , Medellín, Colombia.
authors.forename: E M
authors.initials: EM
authors.lastname: Vásquez-Trespalacios
authors.affiliation: Instituto Nacional de Investigación Oftalmológica, Medellín, Colombia.
authors.forename: C
authors.initials: C
authors.lastname: Sardi-Correa
mesh_terms: D000395:Air Pollutants, Occupational / Q000032:analysis / Q000633:toxicity; D003119:Color Perception Tests; D003117:Color Vision Defects / Q000139:chemically induced* / Q000175:diagnosis; D006801:Humans; D015201:Meta-Analysis as Topic; D064887:Observational Studies as Topic; D009784:Occupational Diseases / Q000139:chemically induced*; D016273:Occupational Exposure; D009930:Organic Chemicals / Q000032:analysis / Q000633:toxicity*; D012997:Solvents / Q000032:analysis / Q000633:toxicity*
chemical_list: D000395:Air Pollutants, Occupational; D009930:Organic Chemicals; D012997:Solvents
keywords: Colour vision; Discromatopsia; Dyschromatopsia; Exposición ocupacional; Lanthony D-15; Occupational exposure; Puesto de trabajo; Solventes; Solvents; Visión de colores; Workplace