title: A case report of severely damaged hip joint caused by SAPHO syndrome treated with 2-stage total hip arthroplasty.
abstract: BACKGROUND
  Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is an increasingly recognized entity. The hip joint is known as a less frequently affected site in SAPHO syndrome, and there has been limited reports about hip joint diseases caused by SAPHO syndrome, and as such adequate treatment for this disease spectrum is still not fully elucidated.
  
  
  METHODS
  We describe the case of a 52-year-old man admitted for SAPHO syndrome who went on to be diagnosed with advanced secondary hip arthritis associated with disabling right hip pain. The diagnosis of SAPHO syndrome was delayed; the patient was given a clinical diagnosis of osteomyelitis and treated with prolonged courses of antibiotics and open surgical debridement at previous tertiary health facility. The patient underwent 2-stage joint replacement surgery in our hospital. At 1 year after the surgery, he is well, with minimal right hip pain and the prosthesis is functioning well.
  
  
  CONCLUSIONS
  This case shows the safety and effectiveness of the 2-stage joint replacement in treating destructive hip disease caused by SAPHO syndrome mimicking infectious arthritis.
authors.affiliation: Department of Orthopedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, South Korea.
authors.forename: Ingwon
authors.initials: I
authors.lastname: Yeo
authors.forename: Hoon-Suk
authors.initials: HS
authors.lastname: Cha
authors.forename: Young Cheol
authors.initials: YC
authors.lastname: Yoon
authors.forename: Youn-Soo
authors.initials: YS
authors.lastname: Park
authors.forename: Seung-Jae
authors.initials: SJ
authors.lastname: Lim
mesh_terms: D020083:Acquired Hyperostosis Syndrome / Q000150:complications*; D019644:Arthroplasty, Replacement, Hip / Q000379:methods*; D006621:Hip Joint; D006801:Humans; D007592:Joint Diseases / Q000209:etiology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D012720:Severity of Illness Index