title: Seroepidemiological Evidence of Subtype H3N8 Influenza Virus Infection among Pet Dogs in China.
abstract: The H3N8 virus and the H3N2 virus are the main subtypes of canine influenza virus (CIV). H3N8 CIV mainly circulates in America, and H3N2 CIV mainly circulates in Asia. However, there was an outbreak of the Asian H3N2 virus in the United States (US) in 2015. Thus, it is important to evaluate the presence of subtype H3N8 virus in dogs in China. From May 2015 to November 2015, 600 sera from pet dogs were collected from Guangzhou, Shanghai, Beijing and Shenzhen for hemagglutination inhibition (HI) assays and microneutralization (MN) assays. Fifty-two (8.66%) of the 600 sera were positive for the subtype H3N2 virus, which matched the previous reports. Five (0.83%) of 600 sera were positive for the subtype H3N8 virus (H3N8 EIV or H3N8 AIV or H3N8 CIV), which is the first report of subtype H3N8 virus infection among dogs in China and remind us to play more attention to this subtype virus. Therefore, further serological and virological surveillance of influenza virus infection among dogs in China is imperative.
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.|Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, People's Republic of China.|Guangdong Engineering and Technological Research Center for Pets, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: Pei
authors.initials: P
authors.lastname: Zhou
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.|Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, People's Republic of China.|Guangdong Engineering and Technological Research Center for Pets, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: San
authors.initials: S
authors.lastname: Huang
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.|Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, People's Republic of China.|Guangdong Engineering and Technological Research Center for Pets, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: Weijie
authors.initials: W
authors.lastname: Zeng
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.|Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, People's Republic of China.|Guangdong Engineering and Technological Research Center for Pets, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: Xin
authors.initials: X
authors.lastname: Zhang
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.|Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, People's Republic of China.|Guangdong Engineering and Technological Research Center for Pets, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: Lifang
authors.initials: L
authors.lastname: Wang
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: Xinliang
authors.initials: X
authors.lastname: Fu
authors.affiliation: College of Veterinary Medicine, South China Agricultural University, Tianhe District, Guangzhou, Guangdong Province, People's Republic of China.|Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases of Guangdong Province, Guangzhou, Guangdong Province, People's Republic of China.|Guangdong Engineering and Technological Research Center for Pets, Guangzhou, Guangdong Province, People's Republic of China.
authors.forename: Shoujun
authors.initials: S
authors.lastname: Li
mesh_terms: D000818:Animals; D000914:Antibodies, Viral / Q000097:blood; D002681:China; D004283:Dog Diseases / Q000097:blood / Q000821:virology*; D004285:Dogs; D006385:Hemagglutination Inhibition Tests; D053123:Influenza A Virus, H3N8 Subtype / Q000302:isolation & purification*; D009976:Orthomyxoviridae Infections / Q000097:blood / Q000662:veterinary* / Q000821:virology; D057805:Pets
chemical_list: D000914:Antibodies, Viral