title: Identification and derivatization of selected cathinones by spectroscopic studies.
abstract: In this study we identified three novel hydrochloride salts of cathinones 2-(pyrrolidin-1-yl)-1-(5,6,7,8-tetrahydronaphthalen-2-yl)pentan-1-one (1a) (TH-PVP), 2-(methylamino)-1-(2-methylphenyl)-1-propanone (1b) (2-MMC) and 1-(4-chlorophenyl)-2-(methylamino)propan-1-one (1c) (4-CMC). Their properties have been examined through combinations of GC-MS, IR, NMR, electronic absorption spectroscopy and single crystal X-ray diffraction method. NMR solution spectra showed readily diagnostic H-1 and C-13 signals from methyl, N-methyl and carbonyl groups. Additionally the use of thionation and amination reactions for identification of selected cathinones was presented.
authors.affiliation: Institute of Chemistry, University of Silesia, ul. Szkolna 9, 40007 Katowice, Poland. Electronic address: jacek.nycz@us.edu.pl.
authors.forename: Jacek E
authors.initials: JE
authors.lastname: Nycz
authors.affiliation: Department of Chemistry, Forensic Laboratory, The Regional Headquarters Katowice, Poland.
authors.forename: Tadeusz
authors.initials: T
authors.lastname: Pazdziorek
authors.affiliation: Institute of Chemistry, University of Silesia, ul. Szkolna 9, 40007 Katowice, Poland.
authors.forename: Grzegorz
authors.initials: G
authors.lastname: Malecki
authors.affiliation: Institute of Chemistry, University of Silesia, ul. Szkolna 9, 40007 Katowice, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Szala
mesh_terms: D000470:Alkaloids / Q000032:analysis / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D009682:Magnetic Resonance Spectroscopy; D014961:X-Ray Diffraction
chemical_list: D000470:Alkaloids; C023665:cathinone
keywords: Aminoguanidine; Cathinone; Guanidine; Lawesson reagent; P4S10; Thionation