title: Diffuse Adenomyomatosis of the Gallbladder in a Child.
abstract: Adenomyomatosis of the gallbladder (ADMG) is characterized by proliferation of the mucosal epithelium and hypertrophy of the muscularis. ADMG is predominantly diagnosed by using ultrasonography. Although ADMG is benign in nature, lithiasis, and chronic inflammation secondary to it may lead to dysplastic changes and cancer. Mucosal invagination through the hypertrophied muscularis results in large intramural diverticula or sinus tracts which are visible at radiology, known as Rokitansky-Aschoff sinuses. Histologically, ADMG manifests with hyperplasia of the muscular layer and proliferation of mucosal glandular tissues. We describe a case of ADMG in an 8-year-old girl presenting with recurrent abdominal pain. Diagnosis was made using ultrasound, and the condition was successfully treated with open cholecystectomy. Ultrasound scanning in children presenting with recurrent abdominal pain may lead to more accurate diagnosis of ADMG during childhood.
authors.affiliation: Departments of *Pediatric Hematology and Oncology †Pediatric Surgery ‡Pathology §Radiogical, Karadeniz Technical University, Trabzon, Turkey.
authors.forename: Nilgün
authors.initials: N
authors.lastname: Eroğlu
authors.forename: Erol
authors.initials: E
authors.lastname: Erduran
authors.forename: Mustafa
authors.initials: M
authors.lastname: İmamoğlu
authors.forename: Zeynep
authors.initials: Z
authors.lastname: Sağnak
authors.forename: Ayşegül
authors.initials: A
authors.lastname: Cansu
mesh_terms: D018194:Adenomyoma / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D002648:Child; D002763:Cholecystectomy; D005260:Female; D005704:Gallbladder / Q000002:abnormalities; D005705:Gallbladder Diseases; D005706:Gallbladder Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006801:Humans; D006965:Hyperplasia / Q000473:pathology; D006984:Hypertrophy; D009092:Mucous Membrane; D014463:Ultrasonography