title: Food allergy in breastfeeding babies. Hidden allergens in human milk.
abstract: BACKGROUND
  Food allergy is a rare disorder among breastfeeding babies.
  
  
  OBJECTIVE
  Our aim was to identify responsible allergens in human milk.
  
  
  METHODS
  We studied babies developing allergic symptoms at the time they were breastfeeding. Skin prick tests (SPT) were performed with breast milk and food allergens. Specific IgE was assessed and IgE Immunoblotting experiments with breast milk were carried out to identify food allergens. Clinical evolution was evaluated after a maternal free diet.
  
  
  RESULTS
  Five babies had confirmed breast milk allergy. Peanut, white egg and/or cow's milk were demonstrated as the hidden responsible allergens. No baby returned to develop symptoms once mother started a free diet. Three of these babies showed tolerance to other food allergens identified in human milk.
  
  
  CONCLUSIONS
  A maternal free diet should be recommended only if food allergy is confirmed in breastfed babies.
authors.affiliation: Department of Allergy, Hospital La Paz Health Research Institute (IdiPAZ), Madrid, Spain. Phone: +34 62 649 3341 Fax: +34 727 7050 E-mail: fmartinmz@gmail.com; mfmartin.hulp@salud.madrid.org.
authors.forename: M F
authors.initials: MF
authors.lastname: Martín-Muñoz
authors.affiliation: Diater Laboratories, R&D Department, Madrid, Spain.
authors.forename: F
authors.initials: F
authors.lastname: Pineda
authors.affiliation: Diater Laboratories, R&D Department, Madrid, Spain.
authors.forename: G
authors.initials: G
authors.lastname: García Parrado
authors.affiliation: Department of Allergy, Hospital La Paz Health Research Institute (IdiPAZ), Madrid, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Guillén
authors.affiliation: Department of Allergy, Hospital La Paz Health Research Institute (IdiPAZ), Madrid, Spain.
authors.forename: D
authors.initials: D
authors.lastname: Rivero
authors.affiliation: Department of Allergy, Hospital La Paz Health Research Institute (IdiPAZ), Madrid, Spain.
authors.forename: T
authors.initials: T
authors.lastname: Belver
authors.affiliation: Department of Allergy, Hospital La Paz Health Research Institute (IdiPAZ), Madrid, Spain.
authors.forename: S
authors.initials: S
authors.lastname: Quirce
mesh_terms: D000485:Allergens / Q000009:adverse effects / Q000276:immunology*; D001942:Breast Feeding / Q000009:adverse effects*; D021181:Egg Hypersensitivity / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology*; D005260:Female; D006801:Humans; D007073:Immunoglobulin E / Q000276:immunology; D007223:Infant; D007428:Intradermal Tests; D008297:Male; D016269:Milk Hypersensitivity / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology*; D008894:Milk Proteins / Q000009:adverse effects / Q000276:immunology*; D008895:Milk, Human / Q000276:immunology*; D021183:Peanut Hypersensitivity / Q000175:diagnosis / Q000178:diet therapy / Q000276:immunology*; D011237:Predictive Value of Tests; D012307:Risk Factors
chemical_list: D000485:Allergens; D008894:Milk Proteins; D007073:Immunoglobulin E
keywords: breastfed infants; food allergy; hidden allergens; human milk