title: Current Treatment of Mesothelioma: Extrapleural Pneumonectomy Versus Pleurectomy/Decortication.
abstract: The role of surgical resection in malignant pleural mesothelioma (MPM) is based on the principle of macroscopic resection of a solid tumor with adjuvant therapy to treat micrometastatic disease. Extrapleural pneumonectomy (EPP) and pleurectomy decortication (P/D) have been developed in this context. Cancer-directed surgery for MPM is associated with a 5-year survival rate of 15%. Evidence indicates that P/D is better tolerated by patients and suggests survival is no worse when compared with EPP. Although EPP is still performed in highly selected cases, the authors advocate radical P/D whenever possible for patients with MPM.
authors.affiliation: Department of Thoracic Surgery, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1023, New York, NY 10029, USA.
authors.forename: Andrea S
authors.initials: AS
authors.lastname: Wolf
authors.affiliation: Department of Thoracic Surgery, Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1023, New York, NY 10029, USA. Electronic address: raja.flores@mountsinai.org.
authors.forename: Raja M
authors.initials: RM
authors.lastname: Flores
mesh_terms: D006801:Humans; D008175:Lung Neoplasms / Q000601:surgery*; D008654:Mesothelioma / Q000601:surgery*; D000086002:Mesothelioma, Malignant; D010994:Pleura / Q000601:surgery*; D010997:Pleural Neoplasms / Q000601:surgery*; D011013:Pneumonectomy / Q000379:methods*; D019616:Thoracic Surgical Procedures / Q000379:methods*
keywords: Extrapleural pneumonectomy; Malignant pleural mesothelioma; Pleurectomy decortication