title: Gastro-oesophageal reflux associated with duodenum inversum: two case reports and a review of the literature.
abstract: Gastro-oesophageal reflux disease (GORD) is a very common paediatric disorder and the majority of patients are treated successfully by primary care physicians. Two infants aged 2 months with GORD which did not respond to conventional medical management are reported; they were diagnosed with duodenum inversum. The first infant failed medical management and required Nissen's fundoplication to control his symptoms. The second infant improved on maximizing medical management without the need for a surgical procedure. These two cases highlight the need for further work-up in patients who do not respond to conventional GORD therapy and/or present with atypical clinical symptoms.
authors.affiliation: a Divisions of Gastroenterology.
authors.forename: Dhiren
authors.identifier: http://orcid.org/0000-0003-4611-0814
authors.initials: D
authors.lastname: Patel
authors.affiliation: b Hospital Medicine.
authors.forename: Roshani
authors.initials: R
authors.lastname: Agarwal
authors.affiliation: c Radiology, Carman and Ann Adams Department of Paediatrics , Children's Hospital of Michigan and Wayne State University , Detroit , Michigan , USA.
authors.forename: William
authors.initials: W
authors.lastname: Powell
authors.affiliation: a Divisions of Gastroenterology.
authors.forename: Namir
authors.initials: N
authors.lastname: Al-Ansari
mesh_terms: D004386:Duodenum / Q000002:abnormalities* / Q000000981:diagnostic imaging; D005471:Fluoroscopy; D005764:Gastroesophageal Reflux / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D007223:Infant; D008297:Male
keywords: Duodenum inversum; Gastro-oesophageal reflux disease (GORD); Intestinal obstruction; Paediatrics