title: Risk and Surveillance of Cancers in Primary Biliary Tract Disease.
abstract: Primary biliary diseases have been associated in several studies with various malignancies. Understanding the risk and optimizing surveillance strategy of these malignancies in this specific subset of patients are an important facet of clinical care. For instance, primary sclerosing cholangitis is associated with an increased risk for cholangiocarcinoma (which is very challenging to diagnose) and when IBD is present for colorectal cancer. On the other hand, primary biliary cirrhosis patients with cirrhosis or not responding to 12 months of ursodeoxycholic acid therapy are at increased risk of hepatocellular carcinoma. In this review we will discuss in detail the risks and optimal surveillance strategies for patients with primary biliary diseases.
authors.affiliation: Department of Internal Medicine, University of North Dakota, Fargo, ND 58102, USA.
authors.forename: Valery
authors.initials: V
authors.lastname: Hrad
authors.affiliation: Department of Internal Medicine, University of North Dakota, Fargo, ND 58102, USA.
authors.forename: Yoftahe
authors.initials: Y
authors.lastname: Abebe
authors.affiliation: Department of Internal Medicine, University of North Dakota, Fargo, ND 58102, USA.
authors.forename: Syed Haris
authors.initials: SH
authors.lastname: Ali
authors.affiliation: Department of Internal Medicine, University of North Dakota, Fargo, ND 58102, USA.
authors.forename: Jared
authors.initials: J
authors.lastname: Velgersdyk
authors.affiliation: Department of General Internal Medicine, MD Anderson Cancer Center, Houston, TX 77030, USA.
authors.forename: Mohammed
authors.identifier: 0000-0002-4598-8177
authors.initials: M
authors.lastname: Al Hallak
authors.affiliation: Department of Internal Medicine, University of North Dakota, Fargo, ND 58102, USA.
authors.forename: Mohamad
authors.identifier: 0000-0003-2659-4946
authors.initials: M
authors.lastname: Imam