title: Nigrosporins A and B, New Phytotoxic and Antibacterial Metabolites Produced by a Fungus Nigrospora oryzae.
abstract: Nigrosporin A and B, two new phytotoxic and antibacterial metabolites were isolated from a culture filtrate of Nigrospora oryzae. The active principles were absorbed on XAD-2 resin and purified by successive ODS-HPLC. The structures were identified by spectroscopic and derivatization analysis as naphthoquinone derivatives. The substances showed phytotoxic activities, such as root elongation inhibition, necrotic effects, oxygen evolution inhibition, starch synthesis inhibition, and CO2 fixation inhibition at concentrations of 10-100 ppm. They also showed growth inhibition activity against Bacillus subtilis in a disc diffusion assay as well as when compared with streptomycin.
authors.affiliation: a Plant Protection Research Laboratory, Japan Tobacco Inc. , 6-2 Umegaoka, Aoba-ku, Yokohama, Kanagawa 227 , Japan.
authors.forename: M
authors.initials: M
authors.lastname: Tanaka
authors.affiliation: a Plant Protection Research Laboratory, Japan Tobacco Inc. , 6-2 Umegaoka, Aoba-ku, Yokohama, Kanagawa 227 , Japan.
authors.forename: T
authors.initials: T
authors.lastname: Fukushima
authors.affiliation: a Plant Protection Research Laboratory, Japan Tobacco Inc. , 6-2 Umegaoka, Aoba-ku, Yokohama, Kanagawa 227 , Japan.
authors.forename: Y
authors.initials: Y
authors.lastname: Tsujino
authors.affiliation: a Plant Protection Research Laboratory, Japan Tobacco Inc. , 6-2 Umegaoka, Aoba-ku, Yokohama, Kanagawa 227 , Japan.
authors.forename: T
authors.initials: T
authors.lastname: Fujimori
keywords: Nigrospora oryzae; anthraquinone derivative; antibacterial activity; photosynthesis inhibition activity; phytotoxic activity