title: Individual differences in the time course of reward processing: Stage-specific links with depression and impulsivity.
abstract: Reward dysfunction has been implicated in a wide range of psychological disorders, including internalizing and externalizing psychopathology. Basic neuroscience research has shown that reward is a multistage process, yet it is unclear how specific stages relate to individual differences in reward sensitivity. The current study utilized event-related potentials elicited during a monetary incentive task to parse sub-stages within anticipatory and consummatory reward processing. Effects of depressive symptoms and trait impulsivity were examined at each sub-stage (N=92). Reward anticipation modulated neural activity across three sub-stages: cue detection (cue-P3), approach behavior (contingent negative variation, CNV), and outcome anticipation (stimulus preceding negativity). Reward delivery modulated activity across two sub-stages: initial evaluation (reward positivity, RewP), and allocation of attention (feedback-P3). Sensation seeking predicted faster reaction times, as well as cue-P3 and RewP amplitudes. Depression and lack of premeditation interacted to predict CNV and RewP amplitudes. Results demonstrate that individual differences in reward functioning are stage-specific.
authors.affiliation: Department of Psychological Sciences, Purdue University, West Lafayette, IN, United States.
authors.forename: Brittni K
authors.initials: BK
authors.lastname: Novak
authors.affiliation: Department of Psychological Sciences, Purdue University, West Lafayette, IN, United States.
authors.forename: Keisha D
authors.initials: KD
authors.lastname: Novak
authors.affiliation: Department of Psychological Sciences, Purdue University, West Lafayette, IN, United States.
authors.forename: Donald R
authors.initials: DR
authors.lastname: Lynam
authors.affiliation: Department of Psychological Sciences, Purdue University, West Lafayette, IN, United States. Electronic address: foti@purdue.edu.
authors.forename: Dan
authors.initials: D
authors.lastname: Foti
mesh_terms: D000293:Adolescent; D000328:Adult; D001288:Attention / Q000502:physiology; D001921:Brain / Q000503:physiopathology; D003265:Contingent Negative Variation; D003463:Cues; D003863:Depression / Q000503:physiopathology / Q000523:psychology*; D005071:Evoked Potentials / Q000502:physiology; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D007175:Impulsive Behavior / Q000502:physiology*; D007206:Individuality; D008297:Male; D008875:Middle Aged; D009042:Motivation / Q000502:physiology; D011930:Reaction Time / Q000502:physiology*; D012201:Reward; D013647:Task Performance and Analysis; D055815:Young Adult
keywords: Depression; EEG; Event-related potentials; Impulsivity; Reward