title: Cholinesterase-based biosensors.
abstract: Recently, cholinesterase-based biosensors are widely used for assaying anticholinergic compounds. Primarily biosensors based on enzyme inhibition are useful analytical tools for fast screening of inhibitors, such as organophosphates and carbamates. The present review is aimed at compilation of the most important facts about cholinesterase based biosensors, types of physico-chemical transduction, immobilization strategies and practical applications.
authors.affiliation: a Faculty of Chemical Technology , Department of Biological and Biochemical Sciences, University of Pardubice , Pardubice , Czech Republic.
authors.forename: Šárka
authors.initials: Š
authors.lastname: Štěpánková
authors.affiliation: a Faculty of Chemical Technology , Department of Biological and Biochemical Sciences, University of Pardubice , Pardubice , Czech Republic.
authors.forename: Katarína
authors.initials: K
authors.lastname: Vorčáková
mesh_terms: D000818:Animals; D015374:Biosensing Techniques / Q000379:methods*; D018680:Cholinergic Antagonists / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D002800:Cholinesterase Inhibitors / Q000032:analysis* / Q000737:chemistry / Q000494:pharmacology*; D002802:Cholinesterases / Q000378:metabolism*; D006801:Humans
chemical_list: D018680:Cholinergic Antagonists; D002800:Cholinesterase Inhibitors; D002802:Cholinesterases
keywords: Applications; biosensor; cholinesterases; immobilization; transducers