title: Production of Enzymes from Marine Actinobacteria.
abstract: Marine actinobacteria are well recognized for their capabilities to produce valuable natural products, which have great potential for applications in medical, agricultural, and fine chemical industries. In addition to producing unique enzymes responsible for biosynthesis of natural products, many marine actinobacteria also produce hydrolytic enzymes which are able to degrade various biopolymers, such as cellulose, xylan, and chitin. These enzymes are important to produce biofuels and biochemicals of interest from renewable biomass. In this chapter, the recent reports of novel enzymes produced by marine actinobacteria are reviewed, and advanced technologies that can be applied to search for novel marine enzymes as well as for improved enzyme production by marine actinobacteria are summarized, which include ribosome engineering, genome mining, as well as synthetic biology studies.
authors.affiliation: State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, China. Electronic address: xqzhao@sjtu.edu.cn.
authors.forename: X Q
authors.initials: XQ
authors.lastname: Zhao
authors.affiliation: School of Life Science and Biotechnology, Dalian University of Technology, Dalian, China.
authors.forename: X N
authors.initials: XN
authors.lastname: Xu
authors.affiliation: School of Life Science and Biotechnology, Dalian University of Technology, Dalian, China.
authors.forename: L Y
authors.initials: LY
authors.lastname: Chen
mesh_terms: D039903:Actinobacteria / Q000201:enzymology*; D059001:Aquatic Organisms / Q000201:enzymology / Q000382:microbiology*; D001704:Biopolymers / Q000378:metabolism; D002480:Cellulase / Q000096:biosynthesis / Q000378:metabolism; D002688:Chitinases / Q000096:biosynthesis / Q000378:metabolism; D004122:Dimethylallyltranstransferase / Q000096:biosynthesis / Q000378:metabolism; D043364:Endo-1,4-beta Xylanases / Q000096:biosynthesis / Q000378:metabolism; D004798:Enzymes / Q000096:biosynthesis* / Q000235:genetics; D054879:Halogenation; D006868:Hydrolysis; D010447:Peptide Hydrolases / Q000096:biosynthesis / Q000378:metabolism
chemical_list: D001704:Biopolymers; D004798:Enzymes; D004122:Dimethylallyltranstransferase; D002688:Chitinases; D002480:Cellulase; D043364:Endo-1,4-beta Xylanases; D010447:Peptide Hydrolases
keywords: Enzyme production; Genome mining; Marine actinobacteria; Ribosome engineering; Synthetic biology