title: [Personalized medicine: evolution or revolution?].
abstract: The principle that personal information is used to provide an individualized prognosis and therapy is an old maxim. Personalized medicine aims to add genetic and molecular information to routinely obtained clinical care data. Thus far, this additional information has not improved prognostic ability in many clinical conditions. Moreover, for most conditions, genetic or molecular knowledge that was used to guide therapeutic decisions has not been shown to improve the clinical outcome.
authors.affiliation: LUMC, afd. Klinische Epidemiologie, Leiden.
authors.forename: O M
authors.initials: OM
authors.lastname: Dekkers
authors.forename: D O
authors.initials: DO
authors.lastname: Mook-Kanamori
authors.forename: F R
authors.initials: FR
authors.lastname: Rosendaal
mesh_terms: D006801:Humans; D057285:Precision Medicine; D011379:Prognosis