title: Effect of the Choice of Primary Chemotherapy on the Cumulative Length of Stay in Hospital for Multiple Myeloma.
abstract: The actual use of hospital beds for patients with multiple myeloma was calculated from a randomised trial of primary treatment with either melphalan and prednisone (MP, 66 patients) or intensive combination chemotherapy with vincristine, cyclophosphamide, lomustine, melphalan and methylprednisolone (MOCCA, 64 patients). The survival of the patients was similar in both arms, and the samples, 20 and 32 patients, respectively, were well representative for the whole arms. The average numbers of hospital days were similar fur both arms. For the first year MP 33.2 (SD 27.6) vs. MOCCA 32.1 (SD 19.0), and during the first to 4th years 78.5 (SD 45.9) vs. 67.8 (SD 34.1). For the year of death it was 50.4 (SD 33.1) vii. 36.3 (SD 27.0), respectivelly. Thus the choice of primary chemotherapy whether conventional or more aggressive had no influence on the actual number of in-patient hospital days concerned. When the combination chemotherapy schedule is well tolerated it can be administered just as well on an ambulatory basis or by using it with very short admissions. It seems that the need for inpatient care for patients with multiple myeloma is mostly related to the complications of the disease itself and to intercurrent disorders including infections.
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: I P
authors.initials: IP
authors.lastname: Palva
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: P
authors.initials: P
authors.lastname: Ahrenberg
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: K
authors.initials: K
authors.lastname: Ala-Harja
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: A
authors.initials: A
authors.lastname: Almqvist
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: H
authors.initials: H
authors.lastname: Hallman
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: A
authors.initials: A
authors.lastname: Hävninen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: M
authors.initials: M
authors.lastname: Ilvonen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: B
authors.initials: B
authors.lastname: Isomaa
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: J
authors.initials: J
authors.lastname: Jouppila
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: E
authors.initials: E
authors.lastname: Järvenpää
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: H
authors.initials: H
authors.lastname: Kilpi
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: S
authors.initials: S
authors.lastname: Koistinen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: E
authors.initials: E
authors.lastname: Koivunen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: K
authors.initials: K
authors.lastname: Kätkä
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: R
authors.initials: R
authors.lastname: Lahtinen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: A
authors.initials: A
authors.lastname: Laitinen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: H
authors.initials: H
authors.lastname: Mäkelä
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: P
authors.initials: P
authors.lastname: Nyländen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: T
authors.initials: T
authors.lastname: Oivanen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: T
authors.initials: T
authors.lastname: Pijlli
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: K
authors.initials: K
authors.lastname: Soininen
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: E
authors.initials: E
authors.lastname: Waris
authors.affiliation: a Hatanpää Hospital, Tampere, University Hospitals of Kuopio, Central Hospitals at Joensuu, Jyräskylä, Kajaani, Keini, Lappeenranta, Kokkola, Pori, Rovaniemi, Savonlinna, Seinäjoki and Vaasa, District Hospital at Pietarsaari.
authors.forename: C
authors.initials: C
authors.lastname: Wasastjerna
keywords: Multiple myeloma; chemotherapy