title: A novel bismuth oxychloride-graphene hybrid nanosheets based non-enzymatic photoelectrochemical glucose sensing platform for high performances.
abstract: A novel non-enzymatic photoelectrochemical (PEC) glucose sensor was first constructed based on the unique two-dimensional (2D) bismuth oxychloride-graphene nanohybrid sheets (BiOCl-G NHS). We have utilized a facile hydrothermal approach for the preparation of BiOCl-G NHS. Results from cyclic voltammetric and differential pulse voltammetric measurements revealed that the BiOCl-G NHS electrode is capable of generating photocurrent for glucose when its surface is irradiated with a light source (wavelength=365nm). The photocurrents produced for the presence of glucose at the bias potential of +0.50V showed a linear dependence on glucose concentration in the range between 0.5 and 10mM and had a detection limit of 0.22mM. The PEC detection of glucose at BiOCl-G NHS was not influenced by the presence of other common interfering species. The glucose levels, as determined by the BiOCl-G NHS sensor, agreed well with those obtained by the commercial glucometers. This novel non-enzymatic PEC glucose sensor exhibited good performances, such as a wider concentration range (500µM-10mM), high sensitivity (1.878µMmM-1cm-2(500µM-2mM) and 127.2µMmM-1cm-2(2mM-10mM)), good selectivity, reproducibility (RSD=2.4%) and applicability to real sample (human serum).
authors.affiliation: Research Institute of Advanced Energy Technology, Kyungpook National University, Daegu, South Korea; Department of Nanoscience and Nanotechnology, Kyungpook National University, Daegu, South Korea.
authors.forename: A I
authors.initials: AI
authors.lastname: Gopalan
authors.affiliation: Department of Chemistry Education, Kyungpook National University, Daegu, South Korea.
authors.forename: N
authors.initials: N
authors.lastname: Muthuchamy
authors.affiliation: Research Institute of Advanced Energy Technology, Kyungpook National University, Daegu, South Korea; Department of Nanoscience and Nanotechnology, Kyungpook National University, Daegu, South Korea; Department of Chemistry Education, Kyungpook National University, Daegu, South Korea. Electronic address: kplee@knu.ac.kr.
authors.forename: K P
authors.initials: KP
authors.lastname: Lee
mesh_terms: D015374:Biosensing Techniques / Q000295:instrumentation*; D001729:Bismuth / Q000737:chemistry*; D001786:Blood Glucose / Q000032:analysis*; D055664:Electrochemical Techniques / Q000295:instrumentation*; D004867:Equipment Design; D006108:Graphite / Q000737:chemistry*; D006801:Humans; D008027:Light; D057230:Limit of Detection; D049329:Nanostructures / Q000737:chemistry* / Q000648:ultrastructure; D015203:Reproducibility of Results
chemical_list: D001786:Blood Glucose; C044685:bismuth oxychloride; D006108:Graphite; D001729:Bismuth
keywords: Hybrid nanosheets; Non-enzymatic; Photoelectrochemical; Wide concentration range