title: Towards a DNA Nanoprocessor: Reusable Tile-Integrated DNA Circuits.
abstract: Modern electronic microprocessors use semiconductor logic gates organized on a silicon chip to enable efficient inter-gate communication. Here, arrays of communicating DNA logic gates integrated on a single DNA tile were designed and used to process nucleic acid inputs in a reusable format. Our results lay the foundation for the development of a DNA nanoprocessor, a small and biocompatible device capable of performing complex analyses of DNA and RNA inputs.
authors.affiliation: Chemistry Department, University of Central Florida, Orlando, FL, 32816, USA.
authors.forename: Yulia V
authors.identifier: 0000-0001-8804-9770
authors.initials: YV
authors.lastname: Gerasimova
authors.affiliation: Chemistry Department, University of Central Florida, Orlando, FL, 32816, USA. Dmitry.Kolpashchikov@ucf.edu.
authors.forename: Dmitry M
authors.identifier: 0000-0002-8682-6553
authors.initials: DM
authors.lastname: Kolpashchikov
mesh_terms: D004247:DNA / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*
chemical_list: D004247:DNA
keywords: DNA logic gates; NOR gates; crossover DNA tiles; molecular beacons; molecular computation