title: Importation of Hybrid Human-Associated Trypanosoma cruzi Strains of Southern South American Origin, Colombia.
abstract: We report the characterization of Trypanosoma cruzi of southern South American origin among humans, domestic vectors, and peridomestic hosts in Colombia using high-resolution nuclear and mitochondrial genotyping. Expanding our understanding of the geographic range of lineage TcVI, which is associated with severe Chagas disease, will help clarify risk of human infection for improved disease control.
authors.forename: Louisa A
authors.initials: LA
authors.lastname: Messenger
authors.forename: Juan David
authors.initials: JD
authors.lastname: Ramirez
authors.forename: Martin S
authors.initials: MS
authors.lastname: Llewellyn
authors.forename: Felipe
authors.initials: F
authors.lastname: Guhl
authors.forename: Michael A
authors.initials: MA
authors.lastname: Miles
mesh_terms: D014355:Chagas Disease / Q000453:epidemiology* / Q000469:parasitology*; D006801:Humans; D009154:Mutation; D010802:Phylogeny; D013020:South America / Q000453:epidemiology; D014349:Trypanosoma cruzi / Q000235:genetics*
keywords: Chagas disease; Colombia; South America; TcV; TcVI; Trypanosoma cruzi; characterization; clones; discrete typing unit; ecologic distribution; genotyping; geographic distribution; high-resolution mitochondrial genotyping; high-resolution nuclear genotyping; humans; hybrid clones; hybridization; interlineage hybrids; parasites; vector-borne infections