title: Elastic membranes in confinement.
abstract: An elastic membrane stretched between two walls takes a shape defined by its length and the volume of fluid it encloses. Many biological structures, such as cells, mitochondria and coiled DNA, have fine internal structure in which a membrane (or elastic member) is geometrically 'confined' by another object. Here, the two-dimensional shape of an elastic membrane in a 'confining' box is studied by introducing a repulsive confinement pressure that prevents the membrane from intersecting the wall. The stage is set by contrasting confined and unconfined solutions. Continuation methods are then used to compute response diagrams, from which we identify the particular membrane mechanics that generate mitochondria-like shapes. Large confinement pressures yield complex response diagrams with secondary bifurcations and multiple turning points where modal identities may change. Regions in parameter space where such behaviour occurs are then mapped.
authors.affiliation: Department of Mechanical Engineering, Clemson University, Clemson, SC 29631, USA jbostwi@clemson.edu.
authors.forename: J B
authors.initials: JB
authors.lastname: Bostwick
authors.affiliation: Department of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, IL 60208, USA.
authors.forename: M J
authors.initials: MJ
authors.lastname: Miksis
authors.affiliation: Department of Engineering Sciences and Applied Mathematics, Northwestern University, Evanston, IL 60208, USA.
authors.forename: S H
authors.initials: SH
authors.lastname: Davis
mesh_terms: D002462:Cell Membrane / Q000737:chemistry / Q000378:metabolism; D004548:Elasticity; D051336:Mitochondrial Membranes / Q000737:chemistry / Q000378:metabolism; D008954:Models, Biological
keywords: bifurcation; biological mechanics; interfaces; membranes; mitochondrion