title: Draft genome sequence of a multidrug-resistant blaOXA-23-producing Acinetobacter baumannii ST208 isolate from China.
abstract: Acinetobacter baumannii has emerged worldwide as an important opportunistic nosocomial pathogen and has become a major public health concern. In this study, the draft genome sequence of A. baumannii TCM331 (ST208/CC92), a multidrug-resistant (MDR) isolate harbouring the blaOXA-23 gene isolated in China, was determined. The genome of TCM331 was sequenced via Illumina HiSeq™ 2000, and bioinformatics analysis was performed. Important antimicrobial resistance determinants were observed in an estimated genome size of 4,058,691bp with 3838 predicted coding regions. In conclusion, these data might facilitate further understanding of the specific genomic features of MDR A. baumannii in China.
authors.affiliation: Department of General Practice, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
authors.forename: Yan
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Respiratory Diseases, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China.
authors.forename: Liyan
authors.initials: L
authors.lastname: Wu
authors.affiliation: Department of General Practice, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, Zhejiang, China.
authors.forename: Yu
authors.initials: Y
authors.lastname: Chen
authors.affiliation: Department of Internal Medicine, People's Hospital of Changshan, Quzhou, Zhejiang, China.
authors.forename: Zhijun
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Department of Emergency Medicine, The Affiliated Hospital of Hangzhou Normal University, Hangzhou, Zhejiang, China. Electronic address: swallowchen120@163.com.
authors.forename: Liqun
authors.initials: L
authors.lastname: Xu
mesh_terms: D000151:Acinetobacter Infections; D040981:Acinetobacter baumannii / Q000187:drug effects / Q000235:genetics*; D000900:Anti-Bacterial Agents; D002681:China; D003428:Cross Infection; D024901:Drug Resistance, Multiple, Bacterial; D016680:Genome, Bacterial; D008826:Microbial Sensitivity Tests; D058885:Multilocus Sequence Typing; D001618:beta-Lactamases / Q000235:genetics
chemical_list: D000900:Anti-Bacterial Agents; D001618:beta-Lactamases
keywords: Acinetobacter baumannii; Multidrug resistance; WGS; Whole-genome sequencing; bla(OXA-23)