title: Lumbar Discectomy: Generic Outcome Measures for Specific Outcome Prediction: A Short-term, Observational, Pilot Study.
abstract: We followed a longitudinal observational design with 2 assessment points, presurgery and postsurgery, in 83 consecutive patients undergoing single-level lumbar discectomy.
  
  
  
  Prognostic data can be gathered from commonly used generic outcome measures to identify patients at risk of persistent leg pain-associated chronicity, following lumbar discectomy SUMMARY OF BACKGROUND DATA:: Suboptimal results observed, following open lumbar discectomy, have been connected to the interplay among presurgery pain characteristics, functional and psychosocial adaptations like persistent pain, disability, and depression. Outcome predictive qualities have been recently attributed to well-known outcome measures. However, most studies on prognostic indicators use multiple tools designs, inhibiting clinical application. Here we elaborate on predictive indications identified in 2 generic patient-rated questionnaires, Short Form-36 (SF-36) and McGill Pain, as many of their domains can evaluate factors related to unfavorable outcomes.
  
  
  
  For the prognostic value calculations, multivariate logistic [Short-Form McGill Pain Questionnaire (SF-MPQ)] and linear regression models (SF-36) were fitted to investigate the association between presurgery and postsurgery scores. In all models, the presurgical score at question was assigned as the dependent variable while age, sex and presurgery score at question were the independent variables.
  
  
  
  Overall, a statistically significant amelioration in both SF-MPQ and SF-36 scores was observed postsurgically. For the SF-MPQ leg cramping, gnawing, burning, and aching pain symptoms, when present presurgically, were the least responsive to treatment. For the SF-36, mental scores overall were less responsive than physical equivalents postoperatively, while general health perception improved only marginally. Differences in pain level scores did not correlate with an equivalent reduction in postsurgery anxiety and depression indices.
  
  
  
  SF-MPQ and SF-36 can assist in treatment decision, as they can readily identify patients at risk of unfavorable outcomes even in primary/clinical settings. The above findings additionally suggest a wider scope of clinical use for the above questionnaires allowing parallel processing and interpretation of the same patient data.
  
  
  
  Level I.
authors.affiliation: Medical School, School of Orthopaedics, Aristotle University of Thessaloniki, Thessaloniki, Greece.
authors.forename: Errikos A
authors.initials: EA
authors.lastname: Koen
authors.forename: Petros D
authors.initials: PD
authors.lastname: Antonarakos
authors.forename: Labrini T
authors.initials: LT
authors.lastname: Katranitsa
authors.forename: Kostas E
authors.initials: KE
authors.lastname: Poulis
authors.forename: Thomas M
authors.initials: TM
authors.lastname: Apostolou
authors.forename: Evangelos A
authors.initials: EA
authors.lastname: Christodoulou
authors.forename: Anastasios G
authors.initials: AG
authors.lastname: Christodoulou
mesh_terms: D001007:Anxiety / Q000175:diagnosis / Q000209:etiology; D003863:Depression / Q000175:diagnosis / Q000209:etiology; D017586:Diskectomy / Q000379:methods*; D005260:Female; D006306:Health Surveys; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D017063:Outcome Assessment, Health Care; D010146:Pain / Q000175:diagnosis / Q000209:etiology*; D010147:Pain Measurement; D010865:Pilot Projects; D011237:Predictive Value of Tests; D013118:Spinal Cord Diseases / Q000150:complications / Q000601:surgery; D011795:Surveys and Questionnaires