title: Role of Predatory Mites in Persistent Nonoccupational Allergic Rhinitis.
abstract: Mites can sensitize and induce atopic disease in predisposed individuals and are an important deteriorating factor in patients with allergic rhinitis, asthma, and atopic dermatitis. Although Pyroglyphidae mites have been extensively studied, very scarce reports are available on Cheyletidae spp. especially regarding human respiratory pathology. The main objective of the present study is to investigate the clinical role of this predator mite (Cheyletus eruditus) as a respiratory antigen in a selected sensitized human population. Fifty-two adult patients were recruited from the outpatient allergy clinic to assess their eligibility for the study. The thirty-seven subjects with persistent allergic rhinitis (PAR) who fulfilled the ARIA criteria had a positive IgE response confirmed by skin prick test (SPT) to C. eruditus. Only those individuals (37/47) with a positive SPT to C. eruditus showed a positive nasal provocation test (NPT), while 10 patients with nonallergic mild-to-moderate persistent rhinitis, control group, had a negative NPT with C. eruditus. The present paper describes a new role for the predator mite Cheyletus eruditus as a respiratory allergen in a selected subset of patients in a subtropical environment afflicted with persistent nonoccupational allergic rhinitis.
authors.affiliation: Allergy Department, Hospital del Tórax, HUNS La Candelaria, 38320 Santa Cruz de Tenerife, Spain.
authors.forename: Paloma
authors.initials: P
authors.lastname: Poza Guedes
authors.affiliation: Allergy Department, Hospital del Tórax, HUNS La Candelaria, 38320 Santa Cruz de Tenerife, Spain.
authors.forename: Inmaculada
authors.initials: I
authors.lastname: Sánchez Machín
authors.affiliation: Department of Clinical Sciences-Division IV, Lund University, 22100 Lund, Sweden.
authors.forename: Víctor
authors.initials: V
authors.lastname: Matheu
authors.affiliation: Laboratorios LETI, 28760 Madrid, Spain.
authors.forename: Víctor
authors.initials: V
authors.lastname: Iraola
authors.affiliation: Allergy Department, Hospital del Tórax, HUNS La Candelaria, 38320 Santa Cruz de Tenerife, Spain.
authors.forename: Ruperto
authors.identifier: 0000-0002-6664-0276
authors.initials: R
authors.lastname: González Pérez
mesh_terms: D000293:Adolescent; D000328:Adult; D000818:Animals; D016022:Case-Control Studies; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D008925:Mites / Q000276:immunology*; D009299:Nasal Provocation Tests; D065631:Rhinitis, Allergic / Q000097:blood / Q000276:immunology / Q000469:parasitology*; D023842:Rhinometry, Acoustic; D012882:Skin Tests; D055815:Young Adult