title: Central-Line-Associated Bloodstream Infections in Québec Intensive Care Units: Results from the Provincial Healthcare-Associated Infections Surveillance Program (SPIN).
abstract: BACKGROUND Following implementation of bundled practices in 2009 in Quebec and Canadian intensive care units (ICUs), we describe CLABSI epidemiology during the last 8 years in the province of Québec (Canada) and compare rates with Canadian and American benchmarks. METHODS CLABSI incidence rates (IRs) and central venous catheter utilization ratios (CVCURs) by year and ICU type were calculated using 2007-2014 data from the Surveillance Provinciale des Infections Nosocomiales (SPIN) program. Using American and Canadian surveillance data, we compared SPIN IRs to rates in other jurisdictions using standardized incidence ratios (SIRs). RESULTS In total, 1,355 lab-confirmed CLABSIs over 911,205 central venous catheter days (CVC days) were recorded. The overall pooled incidence rate (IR) was 1.49 cases per 1,000 CVC days. IRs for adult teaching ICUs, nonteaching ICUs, neonatal ICUs (NICUs), and pediatric ICUs (PICUs) were 1.04, 0.91, 4.20, and 2.15 cases per 1,000 CVC days, respectively. Using fixed SPIN 2007-2009 benchmarks, CLABSI rates had decreased significantly in all ICUs except for PICUs by 2014. Rates declined by 55% in adult teaching ICUs, 52% in adult nonteaching ICUs, and 38% in NICUs. Using dynamic American and Canadian CLABSI rates as benchmarks, SPIN adult teaching ICU rates were significantly lower and adult nonteaching ICUs had lower or comparable rates, whereas NICU and PICU rates were higher. CONCLUSION Québec ICU CLABSI surveillance shows declining CLABSI rates in adult ICUs. The absence of a decrease in CLABSI rate in NICUs and PICUs highlights the need for continued surveillance and analysis of factors contributing to higher rates in these populations. Infect Control Hosp Epidemiol 2016;1-9.
authors.affiliation: 1Department of Epidemiology,Biostatistics,and Occupational Health,McGill University,Montreal (QC),Canada.
authors.forename: Lynne
authors.initials: L
authors.lastname: Li
authors.affiliation: 2Institut National de Santé Publique du Québec,Québec and Montréal (QC),Canada.
authors.forename: Elise
authors.initials: E
authors.lastname: Fortin
authors.affiliation: 2Institut National de Santé Publique du Québec,Québec and Montréal (QC),Canada.
authors.forename: Claude
authors.initials: C
authors.lastname: Tremblay
authors.affiliation: 2Institut National de Santé Publique du Québec,Québec and Montréal (QC),Canada.
authors.forename: Muleka
authors.initials: M
authors.lastname: Ngenda-Muadi
authors.affiliation: 1Department of Epidemiology,Biostatistics,and Occupational Health,McGill University,Montreal (QC),Canada.
authors.forename: Caroline
authors.initials: C
authors.lastname: Quach
mesh_terms: D019985:Benchmarking; D055499:Catheter-Related Infections / Q000453:epidemiology* / Q000517:prevention & control; D002405:Catheterization, Central Venous / Q000009:adverse effects*; D062905:Central Venous Catheters / Q000009:adverse effects*; D003428:Cross Infection / Q000453:epidemiology* / Q000209:etiology* / Q000517:prevention & control; D006761:Hospitals; D006801:Humans; D007362:Intensive Care Units; D007363:Intensive Care Units, Neonatal; D011159:Population Surveillance; D011792:Quebec / Q000453:epidemiology; D014481:United States / Q000453:epidemiology