title: Medulloblastoma with epithelioid features in the cerebellar vermis.
abstract: A 6-year-old girl was admitted with a mass lesion in the cerebellar vermis. She underwent subtotal tumor resection, and on immunohistopathology the tumor consisted of two different parts: typical medulloblastoma (MB) characteristics and atypical teratoid/rhabdoid tumor (AT/RT) features, despite positive integrase interactor 1 expression. The patient was diagnosed with MB with epithelioid features. Chemoradiation therapy was started because of tumor recurrence at the primary site and dissemination to the spinal cord, as determined on magnetic resonance imaging 2 weeks after surgery. The patient died due to tumor progression 13 months after initial diagnosis, although transient partial remission was achieved.
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan. miyata.kenji.735@mail.aichi-med-u.ac.jp.
authors.forename: Kenji
authors.initials: K
authors.lastname: Miyata
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Toshinori
authors.initials: T
authors.lastname: Hori
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Kiyoshi
authors.initials: K
authors.lastname: Yamakawa
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Michihiko
authors.initials: M
authors.lastname: Takasu
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Tomohito
authors.initials: T
authors.lastname: Hayakawa
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Yasuto
authors.initials: Y
authors.lastname: Shimomura
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Atsuko
authors.initials: A
authors.lastname: Iwata
authors.affiliation: Department of Pediatrics, Aichi Medical University, Nagakute, Japan.
authors.forename: Akihisa
authors.initials: A
authors.lastname: Okumura
authors.affiliation: Department of Neurosurgery, Aichi Medical University, Nagakute, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Nakura
authors.affiliation: Department of Neurosurgery, Aichi Medical University, Nagakute, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Jyoko
authors.affiliation: Department of Radiology, Aichi Medical University, Nagakute, Japan.
authors.forename: Yoshimasa
authors.initials: Y
authors.lastname: Mori
authors.affiliation: Department of Pathology, Aichi Medical University, Nagakute, Japan.
authors.forename: Emiko
authors.initials: E
authors.lastname: Takahashi
authors.affiliation: Clinical Department of Pathology, Gunma University Hospital, Maebashi, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Hirato
mesh_terms: D002528:Cerebellar Neoplasms / Q000175:diagnosis* / Q000601:surgery; D065814:Cerebellar Vermis; D002648:Child; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008279:Magnetic Resonance Imaging; D008527:Medulloblastoma / Q000175:diagnosis* / Q000601:surgery; D019635:Neurosurgical Procedures; D014057:Tomography, X-Ray Computed
keywords: atypical teratoid/rhabdoid tumor; cerebellar vermis; integrase interactor 1; medulloblastoma; rhabdoid cell