title: The Effect of Guidance regarding Home Exercise and ADL on Adolescent Females Suffering from Adverse Effects after HPV Vaccination in Japanese Multidisciplinary Pain Centers.
abstract: Background. Two prophylactic papillomavirus (HPV) vaccines have been available for primary prevention of cervical cancer. Although serious adverse effects (AE) were rare, more than 230 women have been suffering from severe AEs such as persistent pain and headache in Japan. Our research group started to treat adolescent females suffering from the AEs. Objective. To survey the characteristics of and the effects of cognitive behavioral therapy on adolescent female suffering from the AEs in Japanese multidisciplinary pain centers. Methods. One hundred and forty-five patients suffering from the AEs were reviewed retrospectively and 105 patients of them were provided guidance on home exercise and activities of daily living based partially on a cognitive-behavioral approach. The intensity of pain was rated by the patients using a numerical rating scale (NRS). Furthermore, the Hospital Anxiety and Depression Scale (HADS) and the Pain Catastrophizing Scale (PCS) were used. Results. Eighty out of the 105 patients who received the guidance were followed up, 10 displayed a marked improvement, and 43 showed some improvement. Conclusions. Guidance on home exercise and activities of daily living based on a cognitive-behavioral approach alleviated the AEs that women suffered from after HPV vaccination in Japan.
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Takahiro
authors.initials: T
authors.lastname: Ushida
authors.affiliation: Department of Pain Medicine, Osaka University, Graduate School of Medicine, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Shibata
authors.affiliation: Pain Clinic, The Jikei University Hospital, Japan.
authors.forename: Masaki
authors.initials: M
authors.lastname: Kitahara
authors.affiliation: Department of Orthopedic Surgery, Fukushima Medical University School of Medicine, Japan.
authors.forename: Shoji
authors.initials: S
authors.lastname: Yabuki
authors.affiliation: Department of Pain and Palliative Medicine, The University of Tokyo Hospital, Japan.
authors.forename: Masahiko
authors.initials: M
authors.lastname: Sumitani
authors.affiliation: Department of Rehabilitation Medicine, Sapporo Medical University, Japan.
authors.forename: Takanori
authors.initials: T
authors.lastname: Murakami
authors.affiliation: Department of Anesthesiology and Pain Management, Juntendo University School of Medicine, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Iseki
authors.affiliation: Department of Psychosomatic Medicine, Kyushu University Hospital, Japan.
authors.forename: Masako
authors.initials: M
authors.lastname: Hosoi
authors.affiliation: Department of Anesthesiology & Critical Care Medicine, Kyushu University Hospital, Japan.
authors.forename: Hiroaki
authors.initials: H
authors.lastname: Shiokawa
authors.affiliation: Department of Orthopedic Surgery, Okayama University Hospital, Japan.
authors.forename: Tomoko
authors.initials: T
authors.lastname: Tetsunaga
authors.affiliation: Department of Anesthesiology and Resuscitology, Okayama University Hospital, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Nishie
authors.affiliation: Interdisciplinary Pain Management Center, Shiga University of Medical Science Hospital, Japan.
authors.forename: Sei
authors.initials: S
authors.lastname: Fukui
authors.affiliation: Department of Orthopedic Surgery, Kochi Medical School, Japan.
authors.forename: Motohiro
authors.initials: M
authors.lastname: Kawasaki
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Sinsuke
authors.initials: S
authors.lastname: Inoue
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Nishihara
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Aono
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Tatunori
authors.initials: T
authors.lastname: Ikemoto
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Takashi
authors.initials: T
authors.lastname: Kawai
authors.affiliation: Multidisciplinary Pain Centre, School of Medicine, Aichi Medical University, Aichi 480-1195, Japan.
authors.forename: Young-Chang
authors.initials: YC
authors.lastname: Arai
mesh_terms: D000203:Activities of Daily Living; D000293:Adolescent; D002648:Child; D005081:Exercise Therapy; D005260:Female; D006261:Headache / Q000209:etiology / Q000523:psychology / Q000534:rehabilitation; D006801:Humans; D007564:Japan / Q000453:epidemiology; D010146:Pain / Q000209:etiology / Q000523:psychology / Q000534:rehabilitation; D018710:Pain Clinics / Q000706:statistics & numerical data; D053918:Papillomavirus Vaccines / Q000009:adverse effects*; D012189:Retrospective Studies; D016896:Treatment Outcome; D055815:Young Adult
chemical_list: D053918:Papillomavirus Vaccines