title: MYC and BCL2 evaluation in routine diagnostics of aggressive B-cell lymphomas - presentation of a work-flow and the experience with 248 cases.
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.|Institute of Pathology, University Hospital Basel, Basel, Switzerland.
authors.forename: Thomas
authors.initials: T
authors.lastname: Menter
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Hanine
authors.initials: H
authors.lastname: Medani
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Raida
authors.initials: R
authors.lastname: Ahmad
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Rashpal
authors.initials: R
authors.lastname: Flora
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Pritesh
authors.initials: P
authors.lastname: Trivedi
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Alistair
authors.initials: A
authors.lastname: Reid
authors.affiliation: Department of Cellular and Molecular Pathology, Hammersmith Hospital Campus, Imperial College Healthcare NHS Trust, London, UK.
authors.forename: Kikkeri N
authors.initials: KN
authors.lastname: Naresh
mesh_terms: D014408:Biomarkers, Tumor; D003955:Diagnostic Tests, Routine / Q000379:methods; D018450:Disease Progression; D005820:Genetic Testing / Q000379:methods; D006801:Humans; D016393:Lymphoma, B-Cell / Q000175:diagnosis* / Q000235:genetics*; D060787:Neoplasm Grading; D019253:Proto-Oncogene Proteins c-bcl-2 / Q000235:genetics*; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics*; D057188:Workflow
chemical_list: D014408:Biomarkers, Tumor; D019253:Proto-Oncogene Proteins c-bcl-2; D016271:Proto-Oncogene Proteins c-myc
keywords: 
  MYC
  ; diffuse large B-cell lymphoma; double-hit lymphomas; fluorescence in situ hybridization; immunohistochemistry