title: A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis.
abstract: We report the case of a patient with gastric adenocarcinoma with multiple liver metastases. This patient showed complete remission for more than 68 months after S-1/cisplatin combination chemotherapy and radical total gastrectomy. The patient, a 63-year-old man, presented with dyspepsia and difficulty in swallowing. Endoscopic findings showed a huge ulcero-infiltrative mass at the lesser curvature of the mid-body, extending to the distal esophagus. Biopsy revealed a poorly differentiated tubular adenocarcinoma. An abdominal computed tomography scan demonstrated multiple hepatic metastases. S-1/cisplatin combination chemotherapy was initiated, and following completion of six cycles of chemotherapy, the gastric masses and hepatic metastatic lesions had disappeared on abdominal computed tomography. Radical total gastrectomy and D2 lymphadenectomy combined with splenectomy were performed. The patient underwent three cycles of S-1/cisplatin combination chemotherapy followed by tegafur-uracil therapy for 1 year. He remained in complete remission for more than 68 months after surgery.
authors.affiliation: Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.
authors.forename: Ch'angbum
authors.initials: C
authors.lastname: Rim
authors.affiliation: Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.
authors.forename: Jung-Ae
authors.initials: JA
authors.lastname: Lee
authors.affiliation: Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.
authors.forename: Soojung
authors.initials: S
authors.lastname: Gong
authors.affiliation: Department of Pathology, Eulji University Hospital, Daejeon, Korea.
authors.forename: Dong Wook
authors.initials: DW
authors.lastname: Kang
authors.affiliation: Department of Emergency Medicine, Eulji University Hospital, Daejeon, Korea.
authors.forename: Heebum
authors.initials: H
authors.lastname: Yang
authors.affiliation: Department of Radiology, Eulji University Hospital, Daejeon, Korea.
authors.forename: Hyun Young
authors.initials: HY
authors.lastname: Han
authors.affiliation: Department of Internal Medicine, Eulji University Hospital, Daejeon, Korea.
authors.forename: Nae Yu
authors.initials: NY
authors.lastname: Kim
keywords: Cisplatin; Gastrectomy, S-1, Cisplatin; Gastric cancer; Liver metastasis