title: Cobalt(II)-Catalyzed Decarboxylative C-H Activation/Annulation Cascades: Regioselective Access to Isoquinolones and Isoindolinones.
abstract: A new cobalt(II)-catalyzed decarboxylative C-H activation/annulation of benzamides and alkynyl carboxylic acids has been described. Alkynyl carboxylic acids were first employed as the coupling partners using inexpensive Co(OAc)2·4H2O as the catalyst. This method enables a switchable cyclization to isoquinolones and isoindolinones with excellent selectivity. Moreover, a catalytic amount of Ag2O was adopted as co-catalyst and O2 (from air) as a terminal oxidant for the preparation of isoquinolones.
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Xin-Qi
authors.initials: XQ
authors.lastname: Hao
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Cong
authors.initials: C
authors.lastname: Du
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Xinju
authors.initials: X
authors.lastname: Zhu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Peng-Xiang
authors.initials: PX
authors.lastname: Li
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Jia-Heng
authors.initials: JH
authors.lastname: Zhang
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Jun-Long
authors.initials: JL
authors.lastname: Niu
authors.affiliation: College of Chemistry and Molecular Engineering, Zhengzhou University , Zhengzhou 450001, P. R. China.
authors.forename: Mao-Ping
authors.initials: MP
authors.lastname: Song