title: SERS of meso-droplets supported on superhydrophobic wires allows exquisitely sensitive detection of dipicolinic acid, an anthrax biomarker, considerably below the infective dose.
abstract: Surface-enhanced Raman measurements of <1 μL analyte/colloid meso-droplets on superhydrophobic wires with hydrophilic tips allowed dipicolinic acid, a spore biomarker for Bacillus anthracis (anthrax), to be detected at 10(-6) mol dm(-3). This is equivalent to 18 spores, significantly below the infective dose of 10(4) spores and 2 orders of magnitude better than previous measurements.
authors.affiliation: Innovative Molecular Materials Group, School of Chemistry and Chemical Engineering, Queen's University Belfast, BT9 5AG, UK. s.bell@qub.ac.uk.
authors.forename: Melody
authors.initials: M
authors.lastname: Cheung
authors.affiliation: Innovative Molecular Materials Group, School of Chemistry and Chemical Engineering, Queen's University Belfast, BT9 5AG, UK. s.bell@qub.ac.uk.
authors.forename: Wendy W Y
authors.initials: WW
authors.lastname: Lee
authors.affiliation: School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
authors.forename: David P
authors.initials: DP
authors.lastname: Cowcher
authors.affiliation: School of Chemistry, Manchester Institute of Biotechnology, University of Manchester, 131 Princess Street, Manchester, M1 7DN, UK.
authors.forename: Royston
authors.initials: R
authors.lastname: Goodacre
authors.affiliation: Innovative Molecular Materials Group, School of Chemistry and Chemical Engineering, Queen's University Belfast, BT9 5AG, UK. s.bell@qub.ac.uk.
authors.forename: Steven E J
authors.initials: SE
authors.lastname: Bell
mesh_terms: D000881:Anthrax; D001408:Bacillus anthracis / Q000302:isolation & purification*; D057927:Hydrophobic and Hydrophilic Interactions; D010848:Picolinic Acids / Q000032:analysis*; D013059:Spectrum Analysis, Raman / Q000379:methods*; D013499:Surface Properties
chemical_list: D010848:Picolinic Acids; C004860:dipicolinic acid