title: Validation of the Polish Version of the Hamilton Rating Scale for Depression in patients with epilepsy.
abstract: Depressive disorders are the most common comorbidities among patients with epilepsy (PWE). The availability of standardized clinical instruments for PWE is limited with scarce validation studies available so far. The aim of the study was to validate the Polish Version of the Hamilton Rating Scale for Depression (HRSD) in adult PWE.
  
  
  
  A group of 96 outpatient PWE were examined by a trained psychiatrist using the Structured Clinical Interview (SCID-I) for DSM-IV-TR and the 17-item Polish Version of HRSD (HRSD-17). Receiver operating characteristic (ROC) curves were used to determine the optimal threshold scores.
  
  
  
  The ROC analyses showed areas under the curve approximately 0.9. For diagnoses of MDD, HRSD-17 demonstrated the best psychometric properties for a cutoff score of 11 with sensitivity of 100%, specificity of 89.3%, positive predictive value of 72.4%, and negative predictive value of 100%.
  
  
  
  The 17-item Polish Version of HRSD proved to be reliable and valid in the epilepsy setting with a cutoff score of 11 points.
authors.affiliation: Department of Psychiatry, Medical University of Gdańsk, Poland. Electronic address: mwiglusz@gumed.edu.pl.
authors.forename: Mariusz S
authors.initials: MS
authors.lastname: Wiglusz
authors.affiliation: Department of Psychiatry, Medical University of Gdańsk, Poland.
authors.forename: Jerzy
authors.initials: J
authors.lastname: Landowski
authors.affiliation: Regional Epilepsy Outpatient Unit, Copernicus Hospital, Gdańsk, Poland.
authors.forename: Lidia
authors.initials: L
authors.lastname: Michalak
authors.affiliation: Department of Psychiatry, Medical University of Gdańsk, Poland.
authors.forename: Wiesław J
authors.initials: WJ
authors.lastname: Cubała
mesh_terms: D000328:Adult; D003863:Depression / Q000150:complications / Q000175:diagnosis*; D003866:Depressive Disorder / Q000150:complications / Q000175:diagnosis*; D039721:Diagnostic and Statistical Manual of Mental Disorders; D004827:Epilepsy / Q000150:complications*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D011044:Poland; D011569:Psychiatric Status Rating Scales; D011594:Psychometrics; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D055815:Young Adult
keywords: DSM-IV-TR; Depressive disorders; Epilepsy; Hamilton Rating Scale for Depression; Major depressive disorder; SCID-I