title: Mining Proteomes Using Bioorthogonal Probes.
abstract: The definition of proteomes in cells and animals at particular stages facilitates an understanding of protein function. In this issue of Cell Chemical Biology, Elliott et al. (2016) report an elegant approach of bioorthogonal labeling and enrichment of proteomes from stochastic orthogonal recoding of translation. With this method, low abundance proteomes can be identified in a multicellular system.
authors.affiliation: Department of Radiology, Huaxi MR Research Center (HMRRC), West China Hospital, West China Medical School, Sichuan University, Chengdu 610041, China. Electronic address: haoxingwu@hmrrc.org.cn.
authors.forename: Haoxing
authors.initials: H
authors.lastname: Wu
authors.affiliation: Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: ndevaraj@ucsd.edu.
authors.forename: Neal K
authors.initials: NK
authors.lastname: Devaraj
mesh_terms: D000818:Animals; D020543:Proteome; D040901:Proteomics
chemical_list: D020543:Proteome