title: Selective Synthesis of Isoquinolines by Rhodium(III)-Catalyzed C-H/N-H Functionalization with α-Substituted Ketones.
abstract: A rhodium(III)-catalyzed C-H/N-H bond functionalization for the synthesis of 1-aminoisoquinolines from aryl amidines and α-MsO/TsO/Cl ketones was achieved under mild reaction conditions. Thus, this approach provides a practical method for the site-selective synthesis of various synthetically valuable isoquinolines with wide functional group tolerance.
authors.affiliation: School of Pharmaceutical Sciences, Jiangnan University , Lihu Road 1800, 214122 Wuxi, P. R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Li
authors.affiliation: School of Pharmaceutical Sciences, Jiangnan University , Lihu Road 1800, 214122 Wuxi, P. R. China.
authors.forename: Zhao
authors.initials: Z
authors.lastname: Zhang
authors.affiliation: School of Pharmaceutical Sciences, Jiangnan University , Lihu Road 1800, 214122 Wuxi, P. R. China.
authors.forename: Mengyao
authors.initials: M
authors.lastname: Tang
authors.affiliation: School of Pharmaceutical Sciences, Jiangnan University , Lihu Road 1800, 214122 Wuxi, P. R. China.
authors.forename: Xiaolei
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Pharmaceutical Sciences, Jiangnan University , Lihu Road 1800, 214122 Wuxi, P. R. China.
authors.forename: Jian
authors.initials: J
authors.lastname: Jin