title: Computational comparison of aortic root stresses in presence of stentless and stented aortic valve bio-prostheses.
abstract: We provide a computational comparison of the performance of stentless and stented aortic prostheses, in terms of aortic root displacements and internal stresses. To this aim, we consider three real patients; for each of them, we draw the two prostheses configurations, which are characterized by different mechanical properties and we also consider the native configuration. For each of these scenarios, we solve the fluid-structure interaction problem arising between blood and aortic root, through Finite Elements. In particular, the Arbitrary Lagrangian-Eulerian formulation is used for the numerical solution of the fluid-dynamic equations and a hyperelastic material model is adopted to predict the mechanical response of the aortic wall and the two prostheses. The computational results are analyzed in terms of aortic flow, internal wall stresses and aortic wall/prosthesis displacements; a quantitative comparison of the mechanical behavior of the three scenarios is reported. The numerical results highlight a good agreement between stentless and native displacements and internal wall stresses, whereas higher/non-physiological stresses are found for the stented case.
authors.affiliation: a Faculty of Informatics, Institute of Computational Science (ICS) , University of Lugano , Lugano , Switzerland .|g Dipartimento di Ingegneria, Nonlinear Physics and Mathematical Modeling Lab , Università Campus Bio-Medico di Roma , Rome , Italy .
authors.forename: M G C
authors.initials: MG
authors.lastname: Nestola
authors.affiliation: b MOX, Dipartimento di Matematica , Politecnico di Milano , Milan , Italy .|c Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Labs , Politecnico di Milano , Milan , Italy .
authors.forename: E
authors.initials: E
authors.lastname: Faggiano
authors.affiliation: b MOX, Dipartimento di Matematica , Politecnico di Milano , Milan , Italy .
authors.forename: C
authors.initials: C
authors.lastname: Vergara
authors.affiliation: b MOX, Dipartimento di Matematica , Politecnico di Milano , Milan , Italy .
authors.forename: R M
authors.initials: RM
authors.lastname: Lancellotti
authors.affiliation: d Radiology unit , Ospedale L.Sacco , Milan , Italy .
authors.forename: S
authors.initials: S
authors.lastname: Ippolito
authors.affiliation: e Cardio-surgery Unit , Ospedale L.Sacco , Milan , Italy .
authors.forename: C
authors.initials: C
authors.lastname: Antona
authors.affiliation: f International Center for Relativistic Astrophysics Network - I.C.R.A.Net , Rome , Italy .|g Dipartimento di Ingegneria, Nonlinear Physics and Mathematical Modeling Lab , Università Campus Bio-Medico di Roma , Rome , Italy .
authors.forename: S
authors.initials: S
authors.lastname: Filippi
authors.affiliation: h SB MATHICSE CMCS, EPFL , Lausanne , Switzerland .
authors.forename: A
authors.initials: A
authors.lastname: Quarteroni
authors.affiliation: e Cardio-surgery Unit , Ospedale L.Sacco , Milan , Italy .
authors.forename: R
authors.initials: R
authors.lastname: Scrofani
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001011:Aorta / Q000601:surgery*; D001021:Aortic Valve / Q000601:surgery*; D001696:Biomechanical Phenomena; D001705:Bioprosthesis; D003198:Computer Simulation; D006350:Heart Valve Prosthesis; D019918:Heart Valve Prosthesis Implantation; D006439:Hemodynamics; D006801:Humans; D008297:Male; D008962:Models, Theoretical; D015607:Stents
keywords: Stentless aortic prosthesis; finite elements analysis; fluid–structure interaction; geometry deflation