title: Patient-reported and radiographic outcomes of minimally invasive transforaminal lumbar interbody fusion for degenerative spondylolisthesis with or without reduction: A comparative study.
abstract: This retrospective study aimed to compare the patient-reported outcomes and radiographic assessment of minimally invasive transforaminal lumbar interbody fusion (MI-TLIF) for degenerative spondylolisthesis with reduction versus in situ fusion. Patients receiving MI-TLIF with reduction were assigned as Group A, and those without reduction were assigned as Group B. Radiographic fusion was assessed using Bridwell's grading criteria. Preoperative and postoperative patient-reported outcomes including visual analogue score (VAS), Oswestry Disability Index (ODI), Japanese Orthopedic Association (JOA) scale and improvement rate were analyzed. There were 41 patients in Group A and 37 patients in Group B. The mean follow-up was 30.78±14.15months in Group A and 28.95±10.75months in Group B (p=0.525). There were no significant differences in hospital stay (p=0.261), estimated blood loss (p=0.639), blood transfusion (p=0.336), operation time (p=0.762) and complications (p=1.00) between the two groups. Radiographic fusion rate was 92.68% (38/41) in Group A, and 81.08% (30/37) in Group B (p=0.110). Significant differences were observed in either 3-month or last follow-up JOA, VAS, and ODI compared with preoperative JOA, VAS, and ODI, respectively (p<0.05). However, there were no significant differences in JOA, VAS, and ODI between the two groups whenever preoperatively, or 3-month postoperatively, or at the last follow-up (p>0.05). According to MacNab criteria, the excellent and good rate was 85.37% in Group A and 86.49% in Group B (p=0.983). MI-TLIF is an effective and satisfactory surgical technique to manage degenerative spondylolisthesis regardless of reduction or not, so routine reduction may not be a requirement in MI-TLIF for degenerative spondylolisthesis.
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Guoxin
authors.initials: G
authors.lastname: Fan
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Hailong
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Xiaofei
authors.initials: X
authors.lastname: Guan
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Guangfei
authors.initials: G
authors.lastname: Gu
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Xinbo
authors.initials: X
authors.lastname: Wu
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Annan
authors.initials: A
authors.lastname: Hu
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China.
authors.forename: Xin
authors.initials: X
authors.lastname: Gu
authors.affiliation: Orthopedic Department, Shanghai Tenth People's Hospital, Tongji University School of Medicine, China. Electronic address: tjhss7418@foxmail.com.
authors.forename: Shisheng
authors.initials: S
authors.lastname: He
mesh_terms: D000368:Aged; D004185:Disability Evaluation; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008159:Lumbar Vertebrae / Q000000981:diagnostic imaging / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019060:Minimally Invasive Surgical Procedures / Q000379:methods*; D010146:Pain / Q000209:etiology; D010147:Pain Measurement; D017060:Patient Satisfaction; D012189:Retrospective Studies; D057566:Self Report; D013123:Spinal Fusion / Q000379:methods*; D013168:Spondylolisthesis / Q000000981:diagnostic imaging / Q000601:surgery*; D016896:Treatment Outcome
keywords: Degenerative spondylolisthesis; Minimally invasive; Patient-reported outcomes; Radiographic outcomes; Reduction; Transforaminal lumbar interbody fusion