title: [Expert recommendations: Hepatitis C and transplantation].
abstract: With the approval of new direct acting antiviral agents (DAA), therapeutic options for patients with chronic hepatitis C virus (HCV) infection are now generally available before and after liver transplantation (LT). Interferon-free DAA regimens are highly effective therapies and provide a good safety profile. However, the body of clinical evidence in this patient population is limited and the best treatment strategies for patients on the waiting list with (de)compensated cirrhosis and after LT are not well defined. The following recommendations for antiviral therapy in the context of LT are based on the currently available literature and clinical experience of experts in the field, and have been discussed in an expert meeting. The aim of this article is to guide clinicians in the decision making when treating patients before and after LT with DAAs.
authors.affiliation: I. Med. Klinik und Poliklinik, Universitätsmedizin Mainz.
authors.forename: T
authors.initials: T
authors.lastname: Zimmermann
authors.affiliation: Klinik für Transplantationsmedizin, Universitätsklinikum Münster.
authors.forename: S
authors.initials: S
authors.lastname: Beckebaum
authors.affiliation: Abteilung Innere Medizin I, Universitätsklinikum Tübingen.
authors.forename: C
authors.initials: C
authors.lastname: Berg
authors.affiliation: Klinik für Gastroenterologie und Hepatologie, Universitätsklinikum Leipzig.
authors.forename: T
authors.initials: T
authors.lastname: Berg
authors.affiliation: Transplantationszentrum, Universitätsklinikum Schleswig-Holstein, Kiel.
authors.forename: F
authors.initials: F
authors.lastname: Braun
authors.affiliation: Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Charité-Universitätsmedizin Berlin.
authors.forename: D
authors.initials: D
authors.lastname: Eurich
authors.affiliation: Klinik für Gastroenterologie und Hepatologie/Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Universitätsklinikum Essen.
authors.forename: K
authors.initials: K
authors.lastname: Herzer
authors.affiliation: Klinik für Allgemein-, Viszeral- und Transplantationschirurgie, Medizinische Fakultät, RWTH Aachen.
authors.forename: U
authors.initials: U
authors.lastname: Neumann
authors.affiliation: Abteilung Innere Medizin IV, Universitätsklinikum Heidelberg.
authors.forename: C
authors.initials: C
authors.lastname: Rupp
authors.affiliation: Klinik und Poliklinik für Hepatobiliäre Chirurgie und Transplantationschirurgie, Universitätsklinikum Hamburg-Eppendorf.
authors.forename: M
authors.initials: M
authors.lastname: Sterneck
authors.affiliation: Medizinische Klinik und Poliklinik I, Universitätsklinikum Bonn.
authors.forename: C
authors.initials: C
authors.lastname: Strassburg
authors.affiliation: Med. Klinik 1, Universitätsklinikum Frankfurt, Frankfurt am Main.
authors.forename: M-W
authors.initials: MW
authors.lastname: Welker
authors.affiliation: Transplantationszentrum München der LMU, München.
authors.forename: R
authors.initials: R
authors.lastname: Zachoval
authors.affiliation: Abteilung Innere Medizin IV, Universitätsklinikum Heidelberg.
authors.forename: D N
authors.initials: DN
authors.lastname: Gotthardt
authors.affiliation: Innere Medizin I, Universitätsklinikum Regensburg.
authors.forename: K
authors.initials: K
authors.lastname: Weigand
authors.affiliation: Klinik für Transplantationsmedizin, Universitätsklinikum Münster.
authors.forename: H
authors.initials: H
authors.lastname: Schmidt
authors.affiliation: Klinik für Gastroenterologie, Hepatologie und Endokrinologie, Medizinische Hochschule Hannover.
authors.forename: H
authors.initials: H
authors.lastname: Wedemeyer
authors.affiliation: I. Med. Klinik und Poliklinik, Universitätsmedizin Mainz.
authors.forename: P R
authors.initials: PR
authors.lastname: Galle
authors.affiliation: Med. Klinik 1, Universitätsklinikum Frankfurt, Frankfurt am Main.
authors.forename: S
authors.initials: S
authors.lastname: Zeuzem
authors.affiliation: Med. Klinik 1, Universitätsklinikum Frankfurt, Frankfurt am Main.
authors.forename: C
authors.initials: C
authors.lastname: Sarrazin
mesh_terms: D000998:Antiviral Agents / Q000008:administration & dosage* / Q000592:standards*; D019317:Evidence-Based Medicine; D005762:Gastroenterology / Q000592:standards; D005858:Germany; D006526:Hepatitis C / Q000175:diagnosis / Q000209:etiology* / Q000628:therapy*; D006801:Humans; D016031:Liver Transplantation / Q000009:adverse effects*; D017410:Practice Guidelines as Topic; D016896:Treatment Outcome; D014773:Virology / Q000592:standards
chemical_list: D000998:Antiviral Agents