title: Comparative alteration in atherogenic indices and hypocholesteremic effect of palm oil and palm oil mill effluent in normal albino rats.
abstract: The comparative hypocholesteremic effect of feeding palm oil and palm oil mill effluent (POME) was investigated in male albino rats. Diets were prepared and designed to contain 50% of energy as carbohydrate, 35% as fat, and 15% as protein. Groups of six rats were each fed one of these diets, while a group was fed pelletized mouse chow which served as the control. Feeding on palm oil and POME led to a significant increase (p < 0.05) in serum total cholesterol, triglyceride, and vLDL. Feeding on POME led to significant increase (p < 0.05) in cholesterol, triglyceride and LDL levels in brain tissues. Increased hepatic LDL level was also observed in POME fed rats. Except for hepatic triglyceride and tissues HDL level, a rather reduced level of the studied lipids was observed in the serum and tissues of palm oil fed rats compared to POME. These results indicate the protective potentials of palm oil against cardiovascular disease, as well as hyperlipidemia that characterize obesity and hypertension; as compared to its effluent.
authors.affiliation: Department of Biochemistry, Bells University of Technology, Ota, Nigeria.
authors.forename: John A
authors.initials: JA
authors.lastname: Ajiboye
authors.affiliation: Department of Food Technology, Federal Institute of Industrial Research, Oshodi, Nigeria.
authors.forename: Ochuko L
authors.initials: OL
authors.lastname: Erukainure
authors.affiliation: Department of Biochemistry, Bells University of Technology, Ota, Nigeria.
authors.forename: Babatunde A
authors.initials: BA
authors.lastname: Lawal
authors.affiliation: Department of Food Technology, Federal Institute of Industrial Research, Oshodi, Nigeria.
authors.forename: Viola A
authors.initials: VA
authors.lastname: Nwachukwu
authors.affiliation: Department of Food Technology, Federal Institute of Industrial Research, Oshodi, Nigeria.
authors.forename: Adesewa O
authors.initials: AO
authors.lastname: Tugbobo-Amisu
authors.affiliation: Department of Food Technology, Federal Institute of Industrial Research, Oshodi, Nigeria.
authors.forename: Ebelechukwu N
authors.initials: EN
authors.lastname: Okafor
keywords: Atherogenic indices; Hypocholestermia; Palm oil and POME