title: Gastrokine 1 mRNA in human sera is not informative biomarker for gastric cancer.
abstract: BACKGROUND
  We aimed to ascertain if Gastrokine 1 mRNA in the sera of patients with gastric cancer might be an informative biomarker for the disease.
  
  
  RESULTS
  Analysis of GKN1 mRNA in serum samples from healthy individuals (n = 23) and from patients with diagnosis of gastric cancer (n = 16), performed by using absolute quantification based on standard curve method, did not show any significative statistical difference between the two unpaired group of individuals.
  
  
  CONCLUSIONS
  Our preliminary results did not confirm GKN1 as a potential biomarker for gastric cancer.
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
authors.forename: Valentina
authors.initials: V
authors.lastname: Villano
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
authors.forename: Chiara Stella
authors.initials: CS
authors.lastname: Di Stadio
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
authors.forename: Antonella
authors.initials: A
authors.lastname: Federico
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
authors.forename: Filomena
authors.initials: F
authors.lastname: Altieri
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy.
authors.forename: Giuseppina
authors.initials: G
authors.lastname: Miselli
authors.affiliation: Hospital A. Cardarelli, Nasples, Italy.
authors.forename: Maurizio
authors.initials: M
authors.lastname: De Palma
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy. emilia.rippa@unina.it.
authors.forename: Emilia
authors.initials: E
authors.lastname: Rippa
authors.affiliation: Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, Via S. Pansini 5, I-8031, Naples, Italy. paolo.arcari@unina.it.|CEINGE, Advanced Biotechnology scarl, Naples, Italy. paolo.arcari@unina.it.
authors.forename: Paolo
authors.identifier: http://orcid.org/0000-0001-9582-0850
authors.initials: P
authors.lastname: Arcari
mesh_terms: D001483:Base Sequence; D014408:Biomarkers, Tumor / Q000097:blood* / Q000235:genetics*; D016022:Case-Control Studies; D005260:Female; D015972:Gene Expression Regulation, Neoplastic; D006801:Humans; D008297:Male; D008875:Middle Aged; D036361:Peptide Hormones / Q000097:blood* / Q000235:genetics*; D012333:RNA, Messenger / Q000235:genetics / Q000378:metabolism; D060888:Real-Time Polymerase Chain Reaction; D013274:Stomach Neoplasms / Q000097:blood* / Q000235:genetics*
chemical_list: D014408:Biomarkers, Tumor; C477000:GKN1 protein, human; D036361:Peptide Hormones; D012333:RNA, Messenger
keywords: Absolute qRT-PCR, 18 kDa antrum mucosal protein; Gastric cancer biomarker; Gastrokine 1