title: Long-Lived Plasma Cells Have a Sweet Tooth.
abstract: Long-lived plasma cells (LLPCs) are durable antibody-producing cells that are key to immunity. Bhattacharya and colleagues find that LLPCs derive their enhanced survival capacity from a higher rate of glucose import. Some of this glucose sustains the cells through glycolysis, while the bulk is required for antibody glycosylation.
authors.affiliation: The Walter and Eliza Hall Institute of Medical Research, Molecular Immunology Division, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3052, Australia. Electronic address: corcoran@wehi.edu.au.
authors.forename: Lynn M
authors.initials: LM
authors.lastname: Corcoran
authors.affiliation: The Walter and Eliza Hall Institute of Medical Research, Molecular Immunology Division, Parkville, Victoria 3052, Australia; Department of Medical Biology, The University of Melbourne, Parkville, Victoria 3052, Australia.
authors.forename: Stephen L
authors.initials: SL
authors.lastname: Nutt
mesh_terms: D000906:Antibodies; D006019:Glycolysis; D006801:Humans; D010950:Plasma Cells / Q000276:immunology*
chemical_list: D000906:Antibodies