title: ISCEV standard for clinical visual evoked potentials: (2016 update).
abstract: Visual evoked potentials (VEPs) can provide important diagnostic information regarding the functional integrity of the visual system. This document updates the ISCEV standard for clinical VEP testing and supersedes the 2009 standard. The main changes in this revision are the acknowledgment that pattern stimuli can be produced using a variety of technologies with an emphasis on the need for manufacturers to ensure that there is no luminance change during pattern reversal or pattern onset/offset. The document is also edited to bring the VEP standard into closer harmony with other ISCEV standards. The ISCEV standard VEP is based on a subset of stimulus and recording conditions that provide core clinical information and can be performed by most clinical electrophysiology laboratories throughout the world. These are: (1) Pattern-reversal VEPs elicited by checkerboard stimuli with large 1 degree (°) and small 0.25° checks. (2) Pattern onset/offset VEPs elicited by checkerboard stimuli with large 1° and small 0.25° checks. (3) Flash VEPs elicited by a flash (brief luminance increment) which subtends a visual field of at least 20°. The ISCEV standard VEP protocols are defined for a single recording channel with a midline occipital active electrode. These protocols are intended for assessment of the eye and/or optic nerves anterior to the optic chiasm. Extended, multi-channel protocols are required to evaluate postchiasmal lesions.
authors.affiliation: West Virginia University Eye Institute, P.O. Box 9193, Morgantown, WV, 26506-9193, USA. jodom@wvu.edu.
authors.forename: J Vernon
authors.initials: JV
authors.lastname: Odom
authors.affiliation: Eye Center, Medical Center and Faculty of Medicine, University of Freiburg, Freiburg, Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Bach
authors.affiliation: Aerpio Therapeutics, Cincinnati, OH, USA.
authors.forename: Mitchell
authors.initials: M
authors.lastname: Brigell
authors.affiliation: Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.
authors.forename: Graham E
authors.initials: GE
authors.lastname: Holder
authors.affiliation: School of Optometry and Vision Sciences, University of Waterloo, Waterloo, Canada.
authors.forename: Daphne L
authors.initials: DL
authors.lastname: McCulloch
authors.affiliation: Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Mizota
authors.affiliation: Department of Neurosciences, Ophthalmic Clinic, Padova University, Padua, Italy.
authors.forename: Alma Patrizia
authors.initials: AP
authors.lastname: Tormene
mesh_terms: D004594:Electrophysiology / Q000592:standards*; D005074:Evoked Potentials, Visual; D006801:Humans; D009900:Optic Nerve / Q000502:physiology; D010364:Pattern Recognition, Visual / Q000502:physiology; D012955:Societies, Medical; D014785:Vision, Ocular / Q000502:physiology*; D014793:Visual Cortex / Q000502:physiology; D014794:Visual Fields / Q000502:physiology
keywords: Flash visual evoked potential; Pattern onset/offset; Pattern-reversal visual evoked potential; Standard; Visual evoked potential