title: Hepatitis and Solitary Left Renal Mass: Renal Hepatocellular Carcinoma.
abstract: Solitary renal tumours are often primary clear cell carcinoma. A 48-year-old man with chronic hepatitis, hepatocellular carcinoma (HCC), and orthotropic liver transplant 6 years ago presented with a solitary left renal mass. Histology revealed metastatic HCC of the left kidney with extensive reactive changes in lymph nodes. Interestingly, biopsy of the transplanted liver showed no evidence of HCC recurrence. Metastatic disease to the kidney often disseminate locally through transcelomic spread, or hematogenous affecting both kidneys. It is important to recognize extrahepatic HCC metastases to the contralateral kidney, especially in patients with active hepatitis, and radical lymph node clearance is needed.
authors.affiliation: Royal Free NHS Foundation Trust, London, United Kingdom. Electronic address: kennethchan1@nhs.net.
authors.forename: Kenneth
authors.initials: K
authors.lastname: Chan
authors.affiliation: Royal Free NHS Foundation Trust, London, United Kingdom.
authors.forename: Jamil
authors.initials: J
authors.lastname: Al-Roubaie
authors.affiliation: Royal Free NHS Foundation Trust, London, United Kingdom.
authors.forename: Soha
authors.initials: S
authors.lastname: El Sheikh
authors.affiliation: Royal Free NHS Foundation Trust, London, United Kingdom.
authors.forename: Faiz
authors.initials: F
authors.lastname: Mumtaz
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000150:complications* / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D019694:Hepatitis B, Chronic / Q000150:complications*; D019698:Hepatitis C, Chronic / Q000150:complications*; D006801:Humans; D007680:Kidney Neoplasms / Q000150:complications* / Q000175:diagnosis / Q000556:secondary* / Q000601:surgery; D008113:Liver Neoplasms / Q000150:complications* / Q000473:pathology*; D008297:Male; D008875:Middle Aged