title: Economic value of ionophores and propylene glycol to prevent disease and treat ketosis in Canada.
abstract: A partial budget model was developed to evaluate the economic value of Rumensin Controlled Release Capsule (CRC) boluses when administered before calving to reduce disease and increase milk production. After accounting for disease incidences in a herd and the percentage by which Rumensin CRC can reduce them, and the increase in milk production attributable to administration of Rumensin CRC, the return on investment (ROI) per lactation was 4:1. Another partial budget model was developed to estimate the economic value of propylene glycol (PG) to treat ketosis when diagnosed by 3 different cow-side tests or when administered to all cows without using any cow-side testing. After accounting for the sensitivity and specificity of each test, ROI per lactation ranged from 2:1 to 4:1. The ROI was 2:1 when no cow-side testing was used. In conclusion, prevention of diseases that occur in the postpartum period and treatment of ketosis after calving yielded a positive ROI that varies based on disease incidence and method of diagnosis.
authors.affiliation: Department of Population Medicine, Ontario Veterinary College (Gohary, LeBlanc, Lissemore, Duffield), School of Hospitality, Food and Tourism Management, College of Business and Economics (Von Massow), University of Guelph, Guelph, Ontario N1G 2W1, Canada; Department of Population Medicine, University of Georgia College of Veterinary Medicine, Athens, Georgia 30602, USA (Overton).
authors.forename: Khaled
authors.initials: K
authors.lastname: Gohary
authors.affiliation: Department of Population Medicine, Ontario Veterinary College (Gohary, LeBlanc, Lissemore, Duffield), School of Hospitality, Food and Tourism Management, College of Business and Economics (Von Massow), University of Guelph, Guelph, Ontario N1G 2W1, Canada; Department of Population Medicine, University of Georgia College of Veterinary Medicine, Athens, Georgia 30602, USA (Overton).
authors.forename: Michael W
authors.initials: MW
authors.lastname: Overton
authors.affiliation: Department of Population Medicine, Ontario Veterinary College (Gohary, LeBlanc, Lissemore, Duffield), School of Hospitality, Food and Tourism Management, College of Business and Economics (Von Massow), University of Guelph, Guelph, Ontario N1G 2W1, Canada; Department of Population Medicine, University of Georgia College of Veterinary Medicine, Athens, Georgia 30602, USA (Overton).
authors.forename: Michael
authors.initials: M
authors.lastname: Von Massow
authors.affiliation: Department of Population Medicine, Ontario Veterinary College (Gohary, LeBlanc, Lissemore, Duffield), School of Hospitality, Food and Tourism Management, College of Business and Economics (Von Massow), University of Guelph, Guelph, Ontario N1G 2W1, Canada; Department of Population Medicine, University of Georgia College of Veterinary Medicine, Athens, Georgia 30602, USA (Overton).
authors.forename: Stephen J
authors.initials: SJ
authors.lastname: LeBlanc
authors.affiliation: Department of Population Medicine, Ontario Veterinary College (Gohary, LeBlanc, Lissemore, Duffield), School of Hospitality, Food and Tourism Management, College of Business and Economics (Von Massow), University of Guelph, Guelph, Ontario N1G 2W1, Canada; Department of Population Medicine, University of Georgia College of Veterinary Medicine, Athens, Georgia 30602, USA (Overton).
authors.forename: Kerry D
authors.initials: KD
authors.lastname: Lissemore
authors.affiliation: Department of Population Medicine, Ontario Veterinary College (Gohary, LeBlanc, Lissemore, Duffield), School of Hospitality, Food and Tourism Management, College of Business and Economics (Von Massow), University of Guelph, Guelph, Ontario N1G 2W1, Canada; Department of Population Medicine, University of Georgia College of Veterinary Medicine, Athens, Georgia 30602, USA (Overton).
authors.forename: Todd F
authors.initials: TF
authors.lastname: Duffield
mesh_terms: D000818:Animals; D002170:Canada; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000191:economics / Q000517:prevention & control*; D003612:Dairying / Q000191:economics; D003692:Delayed-Action Preparations / Q000627:therapeutic use; D005260:Female; D007476:Ionophores; D007662:Ketosis / Q000188:drug therapy / Q000191:economics / Q000662:veterinary*; D018803:Models, Economic; D008985:Monensin / Q000008:administration & dosage / Q000627:therapeutic use; D011247:Pregnancy; D011248:Pregnancy Complications / Q000191:economics / Q000517:prevention & control / Q000662:veterinary; D019946:Propylene Glycol / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D003692:Delayed-Action Preparations; D007476:Ionophores; D019946:Propylene Glycol; D008985:Monensin