title: Pulmonary Hypertension in Children.
abstract: The prevalence of PH is increasing in the pediatric population, because of improved recognition and increased survival of patients, and remains a significant cause of morbidity and mortality. Recent studies have improved the understanding of pediatric PH, but management remains challenging because of a lack of evidence-based clinical trials. The growing contribution of developmental lung disease requires dedicated research to explore the use of existing therapies as well as the creation of novel therapies. Adequate study of pediatric PH will require multicenter collaboration due to the small numbers of patients, multifactorial disease causes, and practice variability.
authors.affiliation: Section of Pediatric Cardiology, Children's Hospital Colorado, University of Colorado School of Medicine, 13123 East 16th Avenue, B100, Aurora, CO 80045, USA. Electronic address: dunbar.ivy@childrenscolorado.org.
authors.forename: Dunbar
authors.initials: D
authors.lastname: Ivy
mesh_terms: D006328:Cardiac Catheterization / Q000379:methods*; D002648:Child; D003952:Diagnostic Imaging / Q000379:methods*; D014943:Global Health; D006330:Heart Defects, Congenital / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology; D006801:Humans; D006976:Hypertension, Pulmonary / Q000175:diagnosis / Q000453:epidemiology / Q000209:etiology; D009017:Morbidity / Q000639:trends
keywords: Bronchopulmonary dysplasia; Pulmonary arterial hypertension; Single-ventricle circulation