title: Mechanical properties and biocompatibility of the sputtered Ti doped hydroxyapatite.
abstract: The hydroxyapatite enriched with Ti were prepared as possible candidates for biomedical applications especially for implantable devices that are in direct contact to the bone. The hydroxyapatites with different Ti content were prepared by RF magnetron sputtering on Ti-6Al-4V alloy using pure hydroxyapatite and TiO2 targets. The content of Ti was modified by changing the RF power fed on TiO2 target. The XPS and FTIR analyses revealed the presence of hydroxyapatite structure. The hardness and elastic modulus of the hydroxyapatite were increased by Ti addition. After 5 days of culture, the cell viability of the Ti-6Al-4V was enhanced by depositing with undoped or doped hydroxyapatite. The Ti additions led to an increase in cell viability of hydroxyapatite, after 5 days of culture. The electron microscopy showed the presence of more cells on the surface of Ti-enriched hydroxyapatite than those observed on the surface of the uncoated alloys or undoped hydroxyapatite.
authors.affiliation: National Institute for Optoelectronics (INOE2000), 409 Atomistilor St., Magurele, Romania. Electronic address: alinava@inoe.ro.
authors.forename: A
authors.initials: A
authors.lastname: Vladescu
authors.affiliation: Department of Chemistry, University College Cork, College Road, Cork, Ireland; Advanced Materials and BioEngineering Research (AMBER) and School of Chemistry, Trinity College Dublin, College Green, Dublin 2, Ireland. Electronic address: sc.padmanabhan@ucc.ie.
authors.forename: S C
authors.initials: SC
authors.lastname: Padmanabhan
authors.affiliation: Dokuz Eylul University, Engineering Faculty, Metallurgical and Materials Engineering Department, Tinaztepe Campus, Izmir, Turkey.
authors.forename: F
authors.initials: F
authors.lastname: Ak Azem
authors.affiliation: National Institute for Optoelectronics (INOE2000), 409 Atomistilor St., Magurele, Romania.
authors.forename: M
authors.initials: M
authors.lastname: Braic
authors.affiliation: Institute of Cellular Biology and Pathology Nicolae Simionescu of the Romanian Academy, 8 B.P. Hasdeu, Bucharest, Romania.
authors.forename: I
authors.initials: I
authors.lastname: Titorencu
authors.affiliation: Dokuz Eylul University, Engineering Faculty, Metallurgical and Materials Engineering Department, Tinaztepe Campus, Izmir, Turkey.
authors.forename: I
authors.initials: I
authors.lastname: Birlik
authors.affiliation: Department of Chemistry, University College Cork, College Road, Cork, Ireland; Advanced Materials and BioEngineering Research (AMBER) and School of Chemistry, Trinity College Dublin, College Green, Dublin 2, Ireland.
authors.forename: M A
authors.initials: MA
authors.lastname: Morris
authors.affiliation: National Institute for Optoelectronics (INOE2000), 409 Atomistilor St., Magurele, Romania.
authors.forename: V
authors.initials: V
authors.lastname: Braic
mesh_terms: D000497:Alloys; D001672:Biocompatible Materials / Q000737:chemistry*; D045744:Cell Line, Tumor; D017886:Durapatite / Q000737:chemistry*; D055119:Elastic Modulus; D006244:Hardness; D006801:Humans; D008422:Materials Testing; D013499:Surface Properties; D023822:Tissue Engineering; D014025:Titanium / Q000737:chemistry*
chemical_list: D000497:Alloys; D001672:Biocompatible Materials; C031462:titanium alloy (TiAl6V4); D017886:Durapatite; D014025:Titanium
keywords: Biomaterial; Cell viability; DNA; Hydroxyapatite; Magnetron sputtering; Roughness