title: Estimation of Prevalence of the Left Ventricular Noncompaction Among Adults.
abstract: The prevalence of left ventricular noncompacted myocardium (LVNC) is not clearly defined yet. The goal of this study was to prospectively assess the prevalence of LVNC in a population of patients assessed for cardiovascular disease and to analyze the coincidence between observers using the echocardiographic criteria for diagnosis of LVNC. We included patients prospectively during a 1-year period. To analyze the concordance between different observers, we performed a blind analysis of 50 patients between 7 operators to calculate Kappa index for each criteria. The analysis of concordance for final diagnosis of LVNC was free-marginal kappa: 0.94. A total of 10,857 patients underwent echocardiography; 2,931 (27%) were normal. LVNC was found in 26 patients (prevalence = 0.24%), 16 patients were women, mean age of 52.6 years. Patients were divided into 2 groups; group A: ejection fraction (EF) <50% (n = 20) and group B: normal systolic function (n = 6). Among abnormal studies, 294 (2.7%) were dilated cardiomyopathies (DCs) Patients with LVNC and EF <50% comprised 6.8% of DC (20 of 294) and 24% (20 of 75) of patients with idiopathic DC (p <0.0001). Group A patients were older and with less presence of women (both p <0.05). In conclusion, the prevalence of LVNC in a population assessed for cardiovascular diseases is low. In contrast, it is very high in the subgroup of patients with idiopathic DC. The group of patients with LVNC and normal LVEF is younger and with a higher presence of women than those with LVNC and depressed LVEF. Coincidence between operators is very good for the identification of echocardiographic criteria.
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina. Electronic address: trotare@hotmail.com.
authors.forename: Ricardo
authors.initials: R
authors.lastname: Ronderos
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Avegliano
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Evelyn
authors.initials: E
authors.lastname: Borelli
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Paola
authors.initials: P
authors.lastname: Kuschnir
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Florencia
authors.initials: F
authors.lastname: Castro
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Gustavo
authors.initials: G
authors.lastname: Sanchez
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Gabriel
authors.initials: G
authors.lastname: Perea
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Mariana
authors.initials: M
authors.lastname: Corneli
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Maria M
authors.initials: MM
authors.lastname: Zanier
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Sol
authors.initials: S
authors.lastname: Andres
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Adriana
authors.initials: A
authors.lastname: Aranda
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Diego
authors.initials: D
authors.lastname: Conde
authors.affiliation: Cardiovascular Imaging Department, Instituto Cardiovascular de Buenos Aires, CABA, Argentina.
authors.forename: Marcelo
authors.initials: M
authors.lastname: Trivi
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D001118:Argentina / Q000453:epidemiology; D016022:Case-Control Studies; D004452:Echocardiography; D018618:Echocardiography, Doppler, Color; D005260:Female; D006801:Humans; D056830:Isolated Noncompaction of the Ventricular Myocardium / Q000000981:diagnostic imaging / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D015995:Prevalence; D011446:Prospective Studies; D013318:Stroke Volume; D018487:Ventricular Dysfunction, Left / Q000000981:diagnostic imaging / Q000453:epidemiology*; D055815:Young Adult