title: Herbal Remedies for Coccidiosis Control: A Review of Plants, Compounds, and Anticoccidial Actions.
abstract: Coccidiosis is the bane of the poultry industry causing considerable economic loss. Eimeria species are known as protozoan parasites to cause morbidity and death in poultry. In addition to anticoccidial chemicals and vaccines, natural products are emerging as an alternative and complementary way to control avian coccidiosis. In this review, we update recent advances in the use of anticoccidial phytoextracts and phytocompounds, which cover 32 plants and 40 phytocompounds, following a database search in PubMed, Web of Science, and Google Scholar. Four plant products commercially available for coccidiosis are included and discussed. We also highlight the chemical and biological properties of the plants and compounds as related to coccidiosis control. Emphasis is placed on the modes of action of the anticoccidial plants and compounds such as interference with the life cycle of Eimeria, regulation of host immunity to Eimeria, growth regulation of gut bacteria, and/or multiple mechanisms. Biological actions, mechanisms, and prophylactic/therapeutic potential of the compounds and extracts of plant origin in coccidiosis are summarized and discussed.
authors.affiliation: Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
authors.forename: Thangarasu
authors.initials: T
authors.lastname: Muthamilselvan
authors.affiliation: Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
authors.forename: Tien-Fen
authors.identifier: 0000-0002-9406-9134
authors.initials: TF
authors.lastname: Kuo
authors.affiliation: Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan.
authors.forename: Yueh-Chen
authors.initials: YC
authors.lastname: Wu
authors.affiliation: Agricultural Biotechnology Research Center, Academia Sinica, Taipei 115, Taiwan; Institute of Pharmacology, National Yang-Ming University, Taipei 112, Taiwan; Department of Life Sciences, National Chung Hsing University, Taichung 402, Taiwan; Institute of Biotechnology, National Taiwan University, Taipei 106, Taiwan.
authors.forename: Wen-Chin
authors.identifier: 0000-0001-6410-2581
authors.initials: WC
authors.lastname: Yang