title: Systems pharmacology in drug development and therapeutic use - A forthcoming paradigm shift.
authors.affiliation: Institute of Pharmacy, Department of Clinical Pharmacy and Biochemistry, Freie Universitaet Berlin, Germany. Electronic address: charlotte.kloft@fu-berlin.de.
authors.forename: Charlotte
authors.initials: C
authors.lastname: Kloft
authors.affiliation: Center for Pharmacometrics and Systems Pharmacology, Department of Pharmaceutics, College of Pharmacy, University of Florida, Orlando, FL, USA.
authors.forename: Miriam N
authors.initials: MN
authors.lastname: Trame
authors.affiliation: Institute of Pharmacy, Clinical Pharmacy, Ernst-Moritz-Arndt-University, Greifswald, Germany.
authors.forename: Christoph A
authors.initials: CA
authors.lastname: Ritter
mesh_terms: D000818:Animals; D055808:Drug Discovery / Q000379:methods / Q000639:trends*; D006801:Humans; D010601:Pharmacology, Clinical / Q000379:methods / Q000639:trends*; D049490:Systems Biology / Q000379:methods / Q000639:trends*