title: Measurement of brain tissue oxygen saturation in term infants using a new portable near-infrared spectroscopy device.
abstract: BACKGROUND
  A small oximeter with the probe attached to the examiner's finger has been developed. The aim of this study was to determine the feasibility of measuring regional oxygenation of the brain tissue using this device in healthy term infants immediately after birth.
  
  
  METHODS
  We conducted a prospective observational study. Using a new near-infrared spectroscopy (NIRS) device, we measured changes in regional cerebral tissue oxygen saturation (crSO2) during the first 10 min of life in 32 healthy term infants after delivery. Arterial oxygen saturation (SpO2) was also simultaneously measured.
  
  
  RESULTS
  Median crSO2increased from 43% (1 min after birth) to 49% (4 min after birth); thereafter, no significant changes were observed. Median SpO2increased constantly from min 3 to min 7, from 77% to 92% and did not change significantly after 8 min. A stable oxygen saturation signal was measured in 59% of infants (crSO2) and in 0% of infants (SpO2) at 1 min, and in 97% (crSO2) and in 78% (SpO2) at 3 min.
  
  
  CONCLUSIONS
  During the transition after birth, crSO2can be more easily and quickly measured in healthy newborn infants using the novel NIRS device than SpO2.
authors.affiliation: Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.
authors.forename: Takaaki
authors.initials: T
authors.lastname: Watanabe
authors.affiliation: Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Ito
authors.affiliation: Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.
authors.forename: Fuyu
authors.initials: F
authors.lastname: Miyake
authors.affiliation: Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Ogawa
authors.affiliation: Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.
authors.forename: Masanori
authors.initials: M
authors.lastname: Tamura
authors.affiliation: Department of Pediatrics, Saitama Medical Center, Saitama Medical University, Kawagoe, Saitama, Japan.
authors.forename: Fumihiko
authors.initials: F
authors.lastname: Namba
mesh_terms: D015415:Biomarkers / Q000378:metabolism; D001921:Brain / Q000378:metabolism*; D006801:Humans; D007231:Infant, Newborn; D010092:Oximetry / Q000295:instrumentation* / Q000379:methods; D010100:Oxygen / Q000378:metabolism*; D011446:Prospective Studies; D019265:Spectroscopy, Near-Infrared / Q000295:instrumentation*
chemical_list: D015415:Biomarkers; D010100:Oxygen
keywords: arterial oxygen saturation; near-infrared spectroscopy; oximetry; regional cerebral tissue oxygen saturation; term infant