title: Who Is Vulnerable to Dengue Fever? A Community Survey of the 2014 Outbreak in Guangzhou, China.
abstract: Unprecedented dengue fever (DF) outbreaks impel China to develop useful disease control strategies. Integrated vector management (IVM) focuses on identifying vulnerable populations and interrupting human-vector contact; however, vulnerable populations have not been clearly identified in China. We conducted a case-control study during the initial stage of the 2014 DF outbreak in Guangzhou, China to assess risk factors for DF infection. Cases were randomly sampled from the National Notifiable Infectious Disease Reporting Information System (NNIDRIS). Controls were healthy individuals recruited from 17 DF infected communities through cluster sampling. A structured questionnaire on demographics, knowledge, practices, and living environment was administered to participants (165 cases; 492 controls). Logistic regression models identified characteristics of vulnerable populations. Awareness of dengue (OR = 0.08, 95% CI = 0.04-0.17), removing trash and stagnant water from around the residence (OR = 0.02, 95% CI = 0.00-0.17), and using mosquito repellent oils (OR = 0.36, 95% CI = 0.16-0.81) were protective factors. Living in an old flat or shed (OR = 2.38, 95% CI = 1.18-4.79) was a risk factor. Coils and bed nets were not protective due to incorrect knowledge of use. Using mosquito repellent oils and other protective measures can reduce vulnerability to DF infection.
authors.affiliation: State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. drchenbin@126.com.|China CDC Key Laboratory of Surveillance and Early-Warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102211, China. drchenbin@126.com.|Xiamen Entry-Exit Inspection and Quarantine Bureau, Xiamen 361012, China. drchenbin@126.com.
authors.forename: Bin
authors.initials: B
authors.lastname: Chen
authors.affiliation: State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. smart_yjun@163.com.|China CDC Key Laboratory of Surveillance and Early-Warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102211, China. smart_yjun@163.com.
authors.forename: Jun
authors.initials: J
authors.lastname: Yang
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China. llyeyq@163.com.
authors.forename: Lei
authors.initials: L
authors.lastname: Luo
authors.affiliation: Guangzhou Center for Disease Control and Prevention, Guangzhou 510440, China. gdgzcdc@163.com.
authors.forename: Zhicong
authors.initials: Z
authors.lastname: Yang
authors.affiliation: State Key Laboratory for Infectious Disease Prevention and Control, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China. liuqiyong@icdc.cn.|China CDC Key Laboratory of Surveillance and Early-Warning on Infectious Disease, Chinese Center for Disease Control and Prevention, Beijing 102211, China. liuqiyong@icdc.cn.
authors.forename: Qiyong
authors.initials: Q
authors.lastname: Liu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000818:Animals; D001364:Awareness; D016022:Case-Control Studies; D002681:China / Q000453:epidemiology; D003715:Dengue / Q000453:epidemiology*; D004777:Environment; D005260:Female; D007722:Health Knowledge, Attitudes, Practice; D006801:Humans; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D009032:Mosquito Control / Q000379:methods; D000072138:Mosquito Vectors; D012111:Residence Characteristics; D012307:Risk Factors; D012959:Socioeconomic Factors; D055815:Young Adult
keywords: dengue fever; knowledge; lifestyle; risk factors; vector control