title: Long-Term Follow-Up Evaluation of Renal Function in Patients with Chronic Kidney Disease Undergoing Cardiac Surgery.
abstract: Background. Acute kidney injury (AKI) is a common complication of cardiac surgery but its long-term consequences, in patients with chronic kidney disease (CKD), are not known. Methods. We compared the long-term prognoses of CKD patients who developed (n = 23) and did not develop (n = 35) AKI during the period of hospitalization after undergoing coronary artery bypass graft (CABG). Fifty-eight patients who survived (69.6 ± 8.4 years old, 72% males, 83% Whites, 52% diabetics, baseline GFR: 46 ± 16 mL/min) were followed up for 47.8 ± 16.4 months and treated for secondary prevention of events. Results. There were 6 deaths, 4 in the AKI+ and 2 in the AKI- group (Log-rank = 0.218), two attributed to CV causes. At the end of the study, renal function was similar in the two groups. One AKI- patient was started on dialysis. Only 4 patients had an increase in serum creatinine ≥ 0.5 mg/dL during follow-up. Conclusion. CKD patients developing AKI that survived the early perioperative period of coronary intervention present good renal and nonrenal long-term prognosis, compared to patients who did not develop AKI.
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Eduesley
authors.identifier: 0000-0001-8545-5677
authors.initials: E
authors.lastname: Santana-Santos
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Felipe Kenji Oshiro
authors.initials: FK
authors.lastname: Kamei
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Tarcísia Karoline
authors.initials: TK
authors.lastname: do Nascimento
authors.affiliation: Vanderbilt University, Nashville, TN, USA.
authors.forename: Anas
authors.initials: A
authors.lastname: Abou Ismail
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Jurema da Silva
authors.initials: Jda S
authors.lastname: Herbas Palomo
authors.affiliation: Universidade de Brasília, Brasília, DF, Brazil.
authors.forename: Marcia Cristina
authors.initials: MC
authors.lastname: da Silva Magro
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Fátima Gil
authors.initials: FG
authors.lastname: Ferreira
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Larissa Bertacchini
authors.initials: LB
authors.lastname: de Oliveira
authors.affiliation: Nursing Department, Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: Adriano Rogério
authors.initials: AR
authors.lastname: Baldacin Rodrigues
authors.affiliation: Heart Institute (InCor), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, SP, Brazil.
authors.forename: José Jayme
authors.initials: JJ
authors.lastname: Galvão de Lima