title: A randomized split-mouth clinical trial comparing  pain experienced during palatal injections with traditional syringe versus controlled-flow delivery Calaject technique.
abstract: OBJECTIVE
  To compare the pain experienced by patients during injections of local anesthesia in the palate using the traditional syringe and the controlled flow technique with the Calaject system.
  
  
  METHODS
  A single-blind, split-mouth, randomized controlled trial was performed. Twenty-five volunteers were recruited in the Dental Hospital of the University of Barcelona, Spain. Each participant received two injections (0.3 mL of mepivacaine 3%), one with the traditional syringe (control side) and another with the Calaject system (experimental side), both during the same session. Pain intensity was evaluated after each injection with a 100-mm visual analog scale (VAS). A descriptive and bivariate statistical analysis was made.
  
  
  RESULTS
  The mean pain experienced was 44.8 mm (standard deviation [SD] 19.0, range 8-72) with the traditional injection and 28.8 mm (SD 19.7, range 8-72) with the Calaject system (P < .001). Moderate/severe pain was more frequently referred in the control side (68%) in comparison with the experimental side (28%).
  
  
  CONCLUSIONS
  Given the parameters of this study's design, the injection of local anesthetics in the palatal area with the Calaject controlled-flow system seems to reduce pain, in comparison to the use of a traditional syringe.
authors.forename: Jeanette
authors.initials: J
authors.lastname: Romero-Galvez
authors.forename: Leonardo
authors.initials: L
authors.lastname: Berini-Aytés
authors.forename: Rui
authors.initials: R
authors.lastname: Figueiredo
authors.forename: Josep
authors.initials: J
authors.lastname: Arnabat-Dominguez
mesh_terms: D000328:Adult; D000766:Anesthesia, Dental / Q000009:adverse effects* / Q000295:instrumentation*; D000772:Anesthesia, Local / Q000009:adverse effects* / Q000295:instrumentation*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D005260:Female; D006801:Humans; D007267:Injections / Q000009:adverse effects / Q000295:instrumentation; D008297:Male; D008619:Mepivacaine / Q000008:administration & dosage*; D010147:Pain Measurement; D010159:Palate; D016037:Single-Blind Method; D013030:Spain; D013594:Syringes; D013813:Therapy, Computer-Assisted / Q000295:instrumentation*
chemical_list: D000779:Anesthetics, Local; D008619:Mepivacaine