title: Enhancement of abdominal structures on MRI at 1.5 and 3 T: a retrospective intraindividual crossover comparison.
abstract: OBJECTIVE
  To quantitatively compare the extent of enhancement of abdominal structures on MRI in an intraindividual fashion at 1.5 and 3 T.
  
  
  METHODS
  HIPAA-compliant, retrospective, longitudinal, intraindividual, crossover study, with waived informed consent, of consecutive individuals scanned at both 1.5 and 3 T closed-bore magnets using gadobenate dimeglumine during different phases of enhancement at tightly controlled arterial phase timing. Quantitative ROI measurements and qualitative sub-phase arterial phase assignments were independently performed by two radiologists. Qualitative discrepancies were resolved by a senior radiologist.
  
  
  RESULTS
  Final population included 60 patients [41 female and 19 male; age, 49.35 ± 18.31 years (range 16-81); weight, 78.88 ± 20.3 kg (range 44.5-136)]. Similar enhancement peak patterns were noted at both field strengths. Interobserver agreement of quantitative evaluations was substantial. Significantly higher amplitudes of enhancement peaks were noted for all abdominal solid organs during all phases at 3 T, except for the pancreas (p = 0.17-0.30). Significantly higher amplitudes of enhancement peaks of the abdominal aorta at 1.5 T were noted.
  
  
  CONCLUSIONS
  Similar peak patterns of enhancement for abdominal structures were observed at 1.5 and 3 T, with solid abdominal organs showing a higher percentage enhancement at 3 T, while unexpectedly higher aortic higher percentage enhancement was observed at 1.5 T.
  
  
  CONCLUSIONS
  • Similar enhancement peak patterns at both field strengths for studied abdominal structures. • Significantly higher percentage enhancement of most abdominal organs at 3 T. • Non-statistically significant trend of higher pancreatic percentage enhancement at 3 T. • Significantly lower abdominal aortic percentage enhancement at 3 T.
authors.affiliation: Department of Radiology, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia.|Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
authors.forename: Mamdoh
authors.initials: M
authors.lastname: AlObaidy
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
authors.forename: Miguel
authors.initials: M
authors.lastname: Ramalho
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
authors.forename: Fernanda
authors.initials: F
authors.lastname: Velloni
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
authors.forename: António P
authors.initials: AP
authors.lastname: Matos
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Herman
authors.affiliation: Department of Radiology, University of North Carolina at Chapel Hill, CB 7510-2001 Old Clinic Bldg., Chapel Hill, NC, 27599-7510, USA. richsem@med.unc.edu.
authors.forename: Richard C
authors.initials: RC
authors.lastname: Semelka
mesh_terms: D000005:Abdomen / Q000000981:diagnostic imaging*; D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003287:Contrast Media; D018592:Cross-Over Studies; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods*; D008137:Longitudinal Studies; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008536:Meglumine / Q000031:analogs & derivatives; D008875:Middle Aged; D009942:Organometallic Compounds; D015203:Reproducibility of Results; D012189:Retrospective Studies; D055815:Young Adult
chemical_list: D003287:Contrast Media; D009942:Organometallic Compounds; C064572:gadobenic acid; D008536:Meglumine
keywords: 1.5 T; 3 T; 3D-GRE; Abdominal; MRI