title: [Multiple organ failure after spontaneous return of circulation in cardiac arrest in children].
abstract: OBJECTIVE
  To assess the frequency of the multiple organ failure and the prognostic value of multiple organ failure scores in children who have recovered from an in-hospital cardiac arrest.
  
  
  METHODS
  A single centre, observational, and retrospective study was conducted on children between 1 month and 16 years old who suffered an in-hospital cardiac arrest and achieved return of spontaneous circulation (ROSC). In the first 24-48hours and between the fifth and the seventh day after ROSC, a record was made of the scores on paediatric severity (PRISM and PIM II) and multiple organ failure scales (PELOD and P-MODS), along with the clinical and analytical data, and including monitoring and treatment, mortality and cause of death.
  
  
  RESULTS
  Of the total of 41 children studied, 70.7% male were male, and the median age was 38 months. The overall mortality during admission was 41.5%, with 14.6% dying in the first 48hours, and 7.6% in the following 3 to 5 days. In the first 48hours, clinical severity and multiple organ failure scores were higher in the patients that died than in survivors (PRISM 29 vs. 21) P=.125, PIM II (26.8% vs. 9.2%) P=.02, PELOD (21 vs. 12) P=.005, and P-MODS (9 vs. 6) P=.001. Between the fifth and seventh day, the scores on the four scales were also higher in patients who died, but only those of the PELOD (20.5 vs. 11) p=.002 and P-MODS (6.5 vs. 3) P=.003 reached statistical significance.
  
  
  CONCLUSIONS
  Mortality in children after return of spontaneous circulation after cardiac arrest is high. The multiple organ failure after return of spontaneous circulation after cardiac arrest in children is associated with increased mortality.
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria, Hospital Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Tania
authors.initials: T
authors.lastname: Carbayo
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria, Hospital Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Alba
authors.initials: A
authors.lastname: de la Mata
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria, Hospital Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Marina
authors.initials: M
authors.lastname: Sánchez
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria, Hospital Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España. Electronic address: pielvi@hotmail.com.
authors.forename: Jesús
authors.initials: J
authors.lastname: López-Herce
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria, Hospital Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Jimena
authors.initials: J
authors.lastname: Del Castillo
authors.affiliation: Servicio de Cuidados Intensivos Pediátricos, Hospital General Universitario Gregorio Marañón, Madrid, España; Instituto de Investigación Sanitaria, Hospital Gregorio Marañón, Madrid, España; Facultad de Medicina, Universidad Complutense de Madrid, Madrid, España.
authors.forename: Angel
authors.initials: A
authors.lastname: Carrillo
mesh_terms: D001775:Blood Circulation; D002648:Child; D002675:Child, Preschool; D005260:Female; D006323:Heart Arrest / Q000628:therapy*; D006801:Humans; D015994:Incidence; D007223:Infant; D008297:Male; D009102:Multiple Organ Failure / Q000453:epidemiology*; D012189:Retrospective Studies
keywords: Cardiac arrest; Cardiopulmonary resuscitation; Fracaso multiorgánico; Multiple organ failure; Parada cardiaca; Prognosis; Pronóstico; Reanimación cardiopulmonar; Recuperación de la circulación espontánea; Return of spontaneous circulation