title: Neonatal outcomes after prelabour rupture of membranes before 24 weeks' gestation.
abstract: OBJECTIVE
  The aim of this study was to determine neonatal outcomes in pregnancies complicated by prelabour rupture of membranes (PROM) before 24 weeks' gestation.
  
  
  METHODS
  We performed a retrospective review of medical records over a 5-year period (2007-2011) at Mater Health Services, South Brisbane, Australia. Data relating to the antenatal and perinatal course of pregnancies complicated by PROM before 24 weeks' gestation were collected. Data were also collected on neonatal diagnoses, management and outcomes for all liveborn infants resulting from these pregnancies.
  
  
  RESULTS
  One hundred and six pregnancies were complicated by PROM before 24 weeks' gestation. Thirty-three (31%) of these pregnancies resulted in delivery at pre-viable gestations (<23 weeks). There were 36 (37%) infants who survived to hospital discharge. At discharge, 47% of infants had chronic lung disease, with 81% of this group requiring supplemental oxygen at home.
  
  
  CONCLUSIONS
  Almost one-third of pregnancies complicated by PROM before 24 weeks resulted in pre-viable preterm delivery. In pregnancies continuing to a viable gestation, there remained a significant risk of neonatal mortality and morbidity, primarily due to respiratory disease.
authors.affiliation: Department of Neonatology, Mater Mothers' Hospital, South Brisbane, Queensland, Australia.|Department of Paediatrics and Child Health, The University of Queensland, Mater Health Services, South Brisbane, Queensland, Australia.
authors.forename: Linda M
authors.initials: LM
authors.lastname: McLaughlin
authors.affiliation: Mater Centre for Maternal Fetal Medicine, Mater Mothers' Hospital, South Brisbane, Queensland, Australia.
authors.forename: Glenn J
authors.initials: GJ
authors.lastname: Gardener
mesh_terms: D001315:Australia / Q000453:epidemiology; D005260:Female; D005322:Premature Rupture of Fetal Membranes / Q000401:mortality; D005865:Gestational Age; D006801:Humans; D011247:Pregnancy; D011256:Pregnancy Outcome; D047928:Premature Birth; D012189:Retrospective Studies
keywords: fetal membrane; infant; newborn; pregnancy outcome; premature; premature rupture