title: Neurology of Pregnancy: A Case-Oriented Review.
abstract: The anatomic and physiologic changes that occur during pregnancy are unique. A neurologist needs to be aware of normal pregnancy-induced physiologic changes in the cardiovascular, renal, hematologic, and autoimmune systems, and the local anatomic changes, which include alteration of body habitus and pelvic ligaments. These changes are clearly advantageous, but in certain circumstances may predispose to pathology. In addition, pregnancy effects treatment of chronic neurologic conditions as regards medication safety and metabolism. This case-oriented review discusses the important aspects of pregnancy physiology and an approach to treatment of common disorders encountered during pregnancy including stroke, multiple sclerosis, epilepsy, and compression neuropathies.
authors.affiliation: Department of Neurology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA. Electronic address: maoneal@partners.org.
authors.forename: Mary Angela
authors.initials: MA
authors.lastname: O'Neal
mesh_terms: D004461:Eclampsia / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D004827:Epilepsy / Q000628:therapy; D005260:Female; D006801:Humans; D009103:Multiple Sclerosis / Q000628:therapy; D009408:Nerve Compression Syndromes / Q000209:etiology / Q000628:therapy; D009422:Nervous System Diseases / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D011247:Pregnancy; D011248:Pregnancy Complications / Q000175:diagnosis / Q000209:etiology / Q000503:physiopathology / Q000628:therapy; D020521:Stroke / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy; D020301:Vasospasm, Intracranial / Q000175:diagnosis / Q000503:physiopathology / Q000628:therapy
keywords: Eclampsia; Epilepsy; Multiple sclerosis; Pregnancy; Stroke