title: Complicated Outcomes After Emergent Lower Extremity Surgery in Patients With Solid Organ Transplants.
abstract: The complications of emergent or urgent surgery in solid organ transplant recipients are unclear. The goal of this nonrandomized retrospective case study, conducted at a large public university teaching hospital, was to determine the following: (1) 90-day postsurgical complications in solid organ transplant recipients who undergo fracture surgery of the lower extremities; (2) 90-day and 1-year mortality rates for this cohort; (3) correlation of particular postsurgical complications with the 90-day or 1-year mortality rate; and (4) correlation of body mass index with the 90-day or 1-year mortality rate. Subjects included 36 solid organ transplant recipients who underwent surgical treatment for 37 emergent or urgent lower extremity fractures within 72 hours of presentation to the emergency department. Patients were followed for all medical and surgical complications for 90 days and for all-cause mortality for 1 year. Within 90 days of surgery, patients had complications that included acute renal failure (15, 40.5%), deep venous thrombosis (3, 8.1%), pulmonary embolus (2, 5.4%), pneumonia (7, 18.9%), superficial surgical site infection (3, 8.1%), and nonorthopedic sepsis (4, 10.8%). In addition, 3 (8.1%) and 5 (13.9%) patients died within 90 days and 1 year, respectively. Hospital readmission correlated with a higher 1-year mortality rate (odds ratio, 14.000; P=.016). Higher body mass index correlated with higher 90-day (odds ratio, 1.425; P=.035) and 1-year (odds ratio, 1.334; P=.033) mortality rates. Solid organ transplant recipients with lower extremity fracture have high 90-day and 1-year mortality rates and may have multiple complications within 90 days of treatment. [Orthopedics. 2016; 39(6):e1063-e1069.].
authors.forename: Alexander T
authors.initials: AT
authors.lastname: Reid
authors.forename: Aaron
authors.initials: A
authors.lastname: Perdue
authors.forename: James A
authors.initials: JA
authors.lastname: Goulet
authors.forename: Christopher B
authors.initials: CB
authors.lastname: Robbins
authors.forename: Aidin Eslam
authors.initials: AE
authors.lastname: Pour
mesh_terms: D058186:Acute Kidney Injury / Q000209:etiology; D000293:Adolescent; D000328:Adult; D000368:Aged; D015992:Body Mass Index; D002423:Cause of Death; D002648:Child; D004638:Emergency Treatment; D005260:Female; D005264:Femoral Fractures / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016377:Organ Transplantation / Q000401:mortality; D019637:Orthopedic Procedures / Q000009:adverse effects* / Q000401:mortality; D010359:Patient Readmission; D011014:Pneumonia / Q000209:etiology; D011655:Pulmonary Embolism / Q000209:etiology; D012189:Retrospective Studies; D018805:Sepsis / Q000209:etiology; D013530:Surgical Wound Infection / Q000209:etiology*; D013978:Tibial Fractures / Q000601:surgery*; D020246:Venous Thrombosis / Q000209:etiology; D055815:Young Adult