title: A new design for electrospinner collecting device facilitates the removal of small diameter tubular scaffolds and paves the way for tissue engineering of capillaries.
abstract: Electrospinning is a technique widely used for tissue engineering. Despite hurdles, electrospun vascular tissue scaffolds has shown great promise in in vitro studies. One problem is the removal of tubular scaffolds from a electrospinning collection device with no unwanted crumpling or tearing, especially for small diameter scaffolds. To tackle this problem we designed a collection device for simple removal of the scaffold from the collector while no chemical pretreatment was required. The scaffolds fabricated on this collecting device maintained their tubular structure and showed favorable surface properties, mechanical strength and biocompatibility. The device offers a new opportunity for tissue engineering researchers to fabricate tubular scaffolds from materials which have not been possible to date and help them improve the quality of synthesized scaffolds.
authors.affiliation: SABZ Biomedicals Research Center, Tehran, Iran.
authors.forename: Abbas
authors.initials: A
authors.lastname: Sohrabi
authors.affiliation: Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran, Iran.
authors.forename: Mahmood
authors.initials: M
authors.lastname: Naderi
authors.affiliation: SABZ Biomedicals Research Center, Tehran, Iran; Core Facilities, Iran University of Medical Sciences, Tehran, Iran.
authors.forename: Fazel
authors.initials: F
authors.lastname: Gorjipour
authors.affiliation: SABZ Biomedicals Research Center, Tehran, Iran.
authors.forename: Abolfazl
authors.initials: A
authors.lastname: Ghamgosar
authors.affiliation: Liver and Pancreatobiliary Diseases Research Center, Digestive Disease Research Institute, Tehran, Iran. Electronic address: n-ahmadbeigi@tums.ac.ir.
authors.forename: Naser
authors.initials: N
authors.lastname: Ahmadbeigi
mesh_terms: D000818:Animals; D001854:Bone Marrow Cells / Q000166:cytology / Q000648:ultrastructure; D002196:Capillaries / Q000502:physiology*; D002460:Cell Line; D004867:Equipment Design; D059630:Mesenchymal Stem Cells / Q000166:cytology / Q000648:ultrastructure; D051379:Mice; D008855:Microscopy, Electron, Scanning; D023822:Tissue Engineering / Q000295:instrumentation* / Q000379:methods*; D054457:Tissue Scaffolds / Q000737:chemistry*
keywords: Electrospinner; Nanofiber; Scaffold