title: Metastatic gastric signet-ring cell carcinoma: A rare cause of acute appendicitis.
abstract: We report a 32-year-old patient who underwent laparoscopy with classical symptoms and signs of acute appendicitis. An inflamed, edematous and non-perforated appendix, also a large amount gelatinous ascites, omental and peritoneal implants were seen. Appendectomy was performed and multiple biopsies were taken from omentum and peritoneum for definitive diagnosis. Histopathologic diagnosis was a metastatic gastric signet-ring cell carcinoma (GSRCC) involving appendix and other specimens. A flat lesion involving corpus to antrum was diagnosed by gastroscopy and GSRCC was verified histopathologically in a tertiary centre and the case evaluated as stage IV gastric carcinoma. This case with no sign of gastric cancer was presented as an acute appendicitis. Metastatic carcinoma to the appendix, causing acute appendicitis is extremely rare in clinical practice and usually associated with high morbidity and mortality.
authors.affiliation: Clinic of General Surgery, Bağcılar Training and Research Hospital, İstanbul, Turkey.
authors.forename: Candaş
authors.initials: C
authors.lastname: Erçetin
authors.affiliation: Clinic of General Surgery, Bakırköy Dr. Sadi Konuk Training and Research Hospital, İstanbul, Turkey.
authors.forename: Ahmet Cem
authors.initials: AC
authors.lastname: Dural
authors.affiliation: Department of General Surgery, Medipol University School of Medicine, İstanbul, Turkey.
authors.forename: Yaşar
authors.initials: Y
authors.lastname: Özdenkaya
authors.affiliation: Department of Gynecology and Obstetrics, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.
authors.forename: Özlem
authors.initials: Ö
authors.lastname: Dural
authors.affiliation: Clinic of Pathology, Iğdır Public Hospital, Iğdır, Turkey.
authors.forename: Huriye Gözde Muhafız
authors.initials: HG
authors.lastname: Dada
authors.affiliation: Department of Pathology, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.
authors.forename: Gülçin
authors.initials: G
authors.lastname: Yeğen
authors.affiliation: Department of Pathology, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.
authors.forename: Yersu
authors.initials: Y
authors.lastname: Kapran
authors.affiliation: Department of General Surgery, İstanbul University İstanbul School of Medicine, İstanbul, Turkey.
authors.forename: Yeşim
authors.initials: Y
authors.lastname: Erbil
keywords: Acute appendicitis; gastric signet-ring cell carcinoma; metastasis