title: Prolonged acyclovir treatment in a child with opercular syndrome related to herpes simplex encephalitis.
abstract: HSV 1 encephalitis is the most common cause of sporadic and focal viral encephalitis. Opercular syndrome is characterized by swallowing and speech difficulties which are associated with deterioration of voluntary control of face, pharynx, tongue and chewing muscles. It can be developed in patients with Herpes simplex encephalitis (HSE). Here, a twelve-year-old boy who was diagnosed with HSE and Opercular syndrome, is presented. The patient recovered without sequela as a result of 30 days of intravenous and 10 days of oral acyclovir treatment. It might be important as well, to personalize and elongate the treatment in terms of prognosis.
authors.affiliation: Division of Child Infectious Diseases, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey.
authors.forename: Arzu
authors.initials: A
authors.lastname: Karli
authors.affiliation: Division of Child Infectious Diseases, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey.
authors.forename: Gülnar
authors.initials: G
authors.lastname: Şensoy
authors.affiliation: Division of Child Neurology, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey. Electronic address: dreminetekin@yahoo.com.
authors.forename: Emine
authors.initials: E
authors.lastname: Tekin
authors.affiliation: Department of Pediatrics, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey.
authors.forename: Ayşe I
authors.initials: AI
authors.lastname: Sofuoğlu
authors.affiliation: Division of Pediatric Radiology, Department of Radiology, Ondokuz Mayıs University Faculty of Medicine, Turkey.
authors.forename: Meltem C
authors.initials: MC
authors.lastname: Bilgici
authors.affiliation: Division of Child Neurology, Children Hospital, Ondokuz Mayıs University Faculty of Medicine, Turkey.
authors.forename: Hamit
authors.initials: H
authors.lastname: Özyürek
mesh_terms: D000212:Acyclovir / Q000008:administration & dosage*; D000998:Antiviral Agents / Q000008:administration & dosage*; D002648:Child; D003680:Deglutition Disorders / Q000175:diagnosis* / Q000473:pathology*; D004401:Dysarthria / Q000175:diagnosis* / Q000473:pathology*; D020803:Encephalitis, Herpes Simplex / Q000150:complications* / Q000188:drug therapy*; D005158:Facial Paralysis / Q000175:diagnosis* / Q000473:pathology*; D006257:Head / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging; D008297:Male
chemical_list: D000998:Antiviral Agents; D000212:Acyclovir
keywords: Acyclovir; Encephalitis; Opercular syndrome