title: Construction of Optically Active Isotwistanes and Aminocyclitols Using Chiral Cyclohexadiene as a Common Intermediate.
abstract: We have developed a new method for synthesizing chiral isotwistane and homoisotwistane skeletons as well as aminocyclitols in a highly stereoselective manner. These results were achieved through the use of a common intermediate, which was derived from the ytterbium-catalyzed asymmetric Diels-Alder reaction of Danishefsky diene.
authors.affiliation: Graduate School of Pharmaceutical Sciences, Chiba University.
authors.forename: Shinji
authors.initials: S
authors.lastname: Harada
authors.forename: Kexin
authors.initials: K
authors.lastname: Li
authors.forename: Ryuto
authors.initials: R
authors.lastname: Kino
authors.forename: Takuya
authors.initials: T
authors.lastname: Takeda
authors.forename: Chia-Hsien
authors.initials: CH
authors.lastname: Wu
authors.forename: Shiharu
authors.initials: S
authors.lastname: Hiraoka
authors.forename: Atsushi
authors.initials: A
authors.lastname: Nishida
mesh_terms: D000473:Alkanes / Q000138:chemical synthesis* / Q000737:chemistry; D001952:Bridged-Ring Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D054812:Cyclitols / Q000138:chemical synthesis* / Q000737:chemistry; D061565:Cycloaddition Reaction; D053138:Cyclohexenes / Q000737:chemistry*; D015394:Molecular Structure; D013237:Stereoisomerism; D015018:Ytterbium / Q000737:chemistry
chemical_list: D000473:Alkanes; D001952:Bridged-Ring Compounds; D054812:Cyclitols; D053138:Cyclohexenes; C048401:1,4-cyclohexadiene; C007548:n-dodecane; D015018:Ytterbium