title: Central Nervous System Complications of Hemorrhagic and Coagulation Disorders.
abstract: Hematologic disorders affect the central nervous system in a variety of ways, producing a wide range of neurologic disturbances. Early identification of these complications allows for early intervention and better outcome. Cross-sectional imaging plays an important role in identifying brain abnormalities and helps the clinician in deciding appropriate course of action and treatment. This article discuss in short the basics of hemostasis including the coagulation cascade and the application of basic laboratory tests in evaluation of hematologic function. Imaging features of various neurologic disorders associated with these clotting and bleeding diatheses are discussed in detail with illustrations.
authors.affiliation: Department of Radiology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA.
authors.forename: Irina
authors.initials: I
authors.lastname: Filatova
authors.affiliation: Department of Radiology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA.
authors.forename: Lindsay L
authors.initials: LL
authors.lastname: Stratchko
authors.affiliation: Department of Radiology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA; Department of Neurology, Hershey Medical Center, The Pennsylvania State University, 500 University Drive, Hershey, PA 17033, USA. Electronic address: skanekar@hmc.psu.edu.
authors.forename: Sangam
authors.initials: S
authors.lastname: Kanekar
mesh_terms: D001778:Blood Coagulation Disorders / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging; D002493:Central Nervous System Diseases / Q000097:blood / Q000000981:diagnostic imaging / Q000209:etiology; D006470:Hemorrhage / Q000097:blood / Q000150:complications / Q000000981:diagnostic imaging; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods*
keywords: CT; Hemorrhagic and coagulation disorders; MRI; Neurologic complications