title: [Is FDG TEP CT practice changing in the management of sarcomas in adults?].
abstract: BACKGROUND
  FDG PET (PET)±computed tomography (CT) has increasingly been used in some areas of oncology imaging. It is sometimes performed outside recommendations, at diagnosis or monitoring of sarcomas. We assessed the value of PET-CT in routine practice in sarcomas.
  
  
  METHODS
  All consecutive sarcoma adult patient charts presented at the multidisciplinary sarcoma meeting in a tertiary care center over a period of 10months were examined in order to analyze the performances of PET-CT when available.
  
  
  RESULTS
  Of 232 patients, 50 (21 %) underwent a PET-CT. Sensitivity and specificity of PET-CT were 94.7 %, 57.1 %, respectively. SUV values were highly variable, including for a given histology or grade. PET-CT resulted in practice changing in 14 % of cases. When extrapulmonary metastases are suspected and for some subtypes of sarcomas, PET-CT could provide additional information because in view of its good sensitivity.
  
  
  CONCLUSIONS
  Given the most frequent pulmonary tropism, first hand chest CT may be sufficient at first diagnostic work-up for the detection of pulmonary metastases. However, the relatively poor specificity suggests that further analyses should be performed to identify clinical situations where PET-CT may be of added value compared to current standards.
authors.affiliation: Centre Lacassagne, département d'oncologie médicale, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Maria
authors.initials: M
authors.lastname: Kogay
authors.affiliation: Centre Lacassagne, département d'oncologie radiothérapie, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Juliette
authors.initials: J
authors.lastname: Thariat
authors.affiliation: Centre Lacassagne, département de médecine nucléaire, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Danielle
authors.initials: D
authors.lastname: Benisvy
authors.affiliation: Centre Lacassagne, département de médecine nucléaire, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Maxime
authors.initials: M
authors.lastname: Dufour
authors.affiliation: Centre Lacassagne, département d'oncologie médicale, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Lauris
authors.initials: L
authors.lastname: Gastaud
authors.affiliation: Centre Lacassagne, département d'oncologie médicale, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Esma
authors.initials: E
authors.lastname: Saada
authors.affiliation: Centre Lacassagne, département d'imagerie médicale, 33, avenue Valombrose, 06189 Nice cedex 2, France.
authors.forename: Antoine
authors.initials: A
authors.lastname: Iannessi
authors.affiliation: Centre Lacassagne, département d'oncologie médicale, 33, avenue Valombrose, 06189 Nice cedex 2, France. Electronic address: antoine.thyss@nice.unicancer.fr.
authors.forename: Antoine
authors.initials: A
authors.lastname: Thyss
mesh_terms: D000328:Adult; D005260:Female; D019788:Fluorodeoxyglucose F18; D006801:Humans; D008175:Lung Neoplasms / Q000000981:diagnostic imaging / Q000556:secondary; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging; D000072078:Positron Emission Tomography Computed Tomography; D019275:Radiopharmaceuticals; D012509:Sarcoma / Q000145:classification / Q000000981:diagnostic imaging* / Q000556:secondary / Q000628:therapy; D012680:Sensitivity and Specificity
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: Adult; Adulte; Bone sarcoma; PET; PET-CT; Sarcome des tissus mous; Sarcome osseux; Soft tissue sarcoma; TEP; TEP-TDM