title: Itaconate and Inflammation, miRs in Zebrafish Embryos, and SHP2 Inhibitor.
abstract: Every month the editors of Cell Chemical Biology bring you highlights of the most recent chemical biology literature. Our July 2016 selection includes reports on itaconate as a key metabolite that regulates inflammation, visualization of microRNA in living zebrafish embryos, and the development of a promising SHP2 inhibitor.
mesh_terms: D000818:Animals; D004625:Embryo, Nonmammalian / Q000378:metabolism*; D004791:Enzyme Inhibitors / Q000737:chemistry / Q000494:pharmacology*; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*; D035683:MicroRNAs / Q000032:analysis*; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11 / Q000037:antagonists & inhibitors* / Q000737:chemistry / Q000378:metabolism; D013386:Succinates / Q000737:chemistry / Q000494:pharmacology* / Q000627:therapeutic use; D015027:Zebrafish / Q000196:embryology*
chemical_list: D004791:Enzyme Inhibitors; D035683:MicroRNAs; D013386:Succinates; D054592:Protein Tyrosine Phosphatase, Non-Receptor Type 11; C005229:itaconic acid