title: Palladium(ii)-catalyzed C-C and C-O bond formation for the synthesis of C1-benzoyl isoquinolines from isoquinoline N-oxides and nitroalkenes.
abstract: C1-Benzoyl isoquinolines can be generated via a palladium(ii)-catalyzed C-C and C-O coupling of isoquinoline N-oxides with aromatic nitroalkenes. The reaction proceeds through remote C-H bond activation and subsequent intramolecular oxygen atom transfer (OAT). In this reaction, the N-O bond was designed as a directing group in the C-H bond activation as well as the source of an oxygen atom.
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People's Republic of China. whengshan@163.com panym2013@hotmail.com.
authors.forename: Jiu-Ling
authors.initials: JL
authors.lastname: Li
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People's Republic of China. whengshan@163.com panym2013@hotmail.com.
authors.forename: Wei-Ze
authors.initials: WZ
authors.lastname: Li
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People's Republic of China. whengshan@163.com panym2013@hotmail.com and College of Chemistry and Chemical Engineering, Jishou University, Jishou 416000, People's Republic of China.
authors.forename: Ying-Chun
authors.initials: YC
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People's Republic of China. whengshan@163.com panym2013@hotmail.com.
authors.forename: Qiu
authors.initials: Q
authors.lastname: Ren
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People's Republic of China. whengshan@163.com panym2013@hotmail.com.
authors.forename: Heng-Shan
authors.initials: HS
authors.lastname: Wang
authors.affiliation: State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences of Guangxi Normal University, Guilin 541004, People's Republic of China. whengshan@163.com panym2013@hotmail.com.
authors.forename: Ying-Ming
authors.initials: YM
authors.lastname: Pan