title: Short-term remote ischemic preconditioning is not associated with improved blood pressure and exercise capacity in young adults.
abstract: We sought to determine whether a 9-day remote ischemic preconditioning (IPC) causes improvements in exercise performance, energetics, and blood pressure. Ten participants (mean age 24 ± 4 years) had no changes in aerobic capacity (preintervention: 38 ± 10 mL/(kg·min)(-1) vs. postintervention: 38 ± 10 mL/(kg·min)(-1)), blood pressure (preintervention: 112 ± 7/66 ± 6 mm Hg vs. postintervention: 112 ± 10/62 ± 5 mm Hg), cardiac phosphocreatinine-to-adenosine-triphosphate ratio (preintervention: 2.1 ± 0.5 vs. postintervention: 2.3 ± 0.4), and postexercise skeletal muscle phosphocreatine recovery (preintervention: 34 ± 11 s vs. postintervention: 31 ± 11 s). Short-term remote IPC may be ineffective in improving these outcomes.
authors.affiliation: a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
authors.forename: Laura
authors.initials: L
authors.lastname: Banks
authors.affiliation: b Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.|d Physiology and Experimental Medicine, the Hospital for Sick Children, Toronto, ON, Canada.
authors.forename: Greg D
authors.initials: GD
authors.lastname: Wells
authors.affiliation: a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
authors.forename: Nadia A
authors.initials: NA
authors.lastname: Clarizia
authors.affiliation: a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
authors.forename: Emilie
authors.initials: E
authors.lastname: Jean-St-Michel
authors.affiliation: a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.
authors.forename: Adam L
authors.initials: AL
authors.lastname: McKillop
authors.affiliation: a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.|c Department of Pediatrics, University of Toronto, Toronto, ON, Canada.
authors.forename: Andrew N
authors.initials: AN
authors.lastname: Redington
authors.affiliation: a Labatt Family Heart Centre, Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada.|c Department of Pediatrics, University of Toronto, Toronto, ON, Canada.
authors.forename: Brian W
authors.initials: BW
authors.lastname: McCrindle
mesh_terms: D000255:Adenosine Triphosphate / Q000097:blood; D000293:Adolescent; D000328:Adult; D001794:Blood Pressure; D015992:Body Mass Index; D004734:Energy Metabolism; D015444:Exercise; D005080:Exercise Test; D017079:Exercise Tolerance; D005260:Female; D006801:Humans; D019194:Ischemic Preconditioning; D016014:Linear Models; D008279:Magnetic Resonance Imaging; D008297:Male; D018482:Muscle, Skeletal / Q000502:physiology; D010101:Oxygen Consumption; D010725:Phosphocreatine / Q000031:analogs & derivatives / Q000097:blood; D057185:Sedentary Behavior; D013997:Time Factors; D055815:Young Adult
chemical_list: D010725:Phosphocreatine; C025403:phosphocreatinine; D000255:Adenosine Triphosphate
keywords: cardiac energy metabolism; consommation d’oxygène de pointe; ischemia–reperfusion; ischémie-reperfusion; magnetic resonance spectroscopy; métabolisme énergétique cardiaque; peak oxygen consumption; phosphocreatine recovery; phosphocréatine de récupération; spectroscopie par résonance magnétique