title: Changes in serum NGF levels after the exercise load in dogs: a pilot study.
abstract: Serum nerve growth factor (NGF) levels are increased by the external stress in mice, humans and horses; however, similar variations have been unclear in dogs. Since dogs are usually subjected to conditions of work, exercise and activity as important partners of humans, we measured serum NGF levels post-exercise and compared them with serum cortisol levels, as a biomarker of physical stress. Serum cortisol levels were immediately elevated post-exercise and returned to basal levels within 1 hr. On the other hand, serum NGF levels were significantly increased 1 hr post-exercise and gradually returned to basal levels. Further research is necessary; nevertheless, we have demonstrated for the first time that serum NGF levels respond to exercise stress in dogs.
authors.affiliation: Cooperative Major in Advanced Health Science, Graduate School of Bio-Applications and System Engineering, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan.
authors.forename: Izumi
authors.initials: I
authors.lastname: Ando
authors.forename: Kaoru
authors.initials: K
authors.lastname: Karasawa
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Matsuda
authors.forename: Akane
authors.initials: A
authors.lastname: Tanaka
mesh_terms: D000818:Animals; D004285:Dogs / Q000502:physiology*; D005260:Female; D006339:Heart Rate; D006854:Hydrocortisone / Q000097:blood*; D008297:Male; D020932:Nerve Growth Factor / Q000097:blood*; D010805:Physical Conditioning, Animal; D005082:Physical Exertion; D010865:Pilot Projects
chemical_list: D020932:Nerve Growth Factor; D006854:Hydrocortisone