title: Klebsiella pneumoniae Infection Leads to a Poor Visual Outcome in Endogenous Endophthalmitis: A 12-year Experience in Southern Taiwan.
abstract: OBJECTIVE
  To compare the characteristics, visual outcome, and prognostic factors of patients with endogenous endophthalmitis and to determine the association of endophthalmitis with Klebsiella pneumoniae infection.
  
  
  METHODS
  We retrospectively analyzed records of patients diagnosed with endogenous endophthalmitis from January 2002 to August 2013.
  
  
  RESULTS
  A total of 86 patients were diagnosed with endogenous endophthalmitis; 48 patients were infected with K. pneumoniae, 28 patients were infected with other pathogens, and 10 were culture-negative. Diabetes mellitus was more prevalent among patients infected with K. pneumoniae. Liver abscess and urinary tract infection were the leading sources of infection in patients with and without a K. pneumoniae infection, respectively. In patients with endogenous endophthalmitis, poor initial vision (p<0.001) and K. pneumoniae infection (p = 0.048) were significantly associated with a poor visual outcome.
  
  
  CONCLUSIONS
  Poor initial vision and K. pneumoniae infection were significantly associated with poorer visual outcome for patients with endogenous endophthalmitis.
authors.affiliation: a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.
authors.forename: Shih-Chou
authors.initials: SC
authors.lastname: Chen
authors.affiliation: a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.
authors.forename: Ying-Yen
authors.initials: YY
authors.lastname: Lee
authors.affiliation: a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.
authors.forename: Ya-Hsin
authors.initials: YH
authors.lastname: Chen
authors.affiliation: b Program of Health-Business Administration , Fooyin University , Kaohsiung , Taiwan.
authors.forename: Huey-Shyan
authors.initials: HS
authors.lastname: Lin
authors.affiliation: a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.|c School of Medicine , National Yang-Ming University , Taipei , Taiwan.
authors.forename: Tsung-Tien
authors.initials: TT
authors.lastname: Wu
authors.affiliation: a Department of Ophthalmology , Kaohsiung Veterans General Hospital , Kaohsiung , Taiwan.|c School of Medicine , National Yang-Ming University , Taipei , Taiwan.
authors.forename: Shwu-Jiuan
authors.initials: SJ
authors.lastname: Sheu
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001082:Aqueous Humor / Q000382:microbiology; D009877:Endophthalmitis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D015818:Eye Infections, Bacterial / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D005260:Female; D006801:Humans; D007710:Klebsiella Infections / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology*; D007711:Klebsiella pneumoniae / Q000302:isolation & purification*; D008297:Male; D008875:Middle Aged; D012189:Retrospective Studies; D013624:Taiwan; D014786:Vision Disorders / Q000382:microbiology*; D014792:Visual Acuity; D014822:Vitreous Body / Q000382:microbiology
chemical_list: D000900:Anti-Bacterial Agents
keywords: Endogenous endophthalmitis; Klebsiella pneumoniae; Taiwan; liver abscess; prognosis