title: Neuroimaging in Leukemia.
abstract: Leukemias are a heterogeneous group of hematologic malignancies that results from uncontrolled neoplastic proliferation of undifferentiated or partially differentiated hematopoietic cells. Patients with acute leukemia can have a variety of craniocerebral complications, which can result from direct leukemic involvement, secondary to cerebrovascular or infectious complications of leukemia, or can be treatment related. Imaging plays a central role in evaluating the central nervous system during treatment in patients with leukemia. CT scan is usually considered an effective initial imaging modality to evaluate for cerebrovascular complications. MRI is considered the imaging modality of choice due to its versatility.
authors.affiliation: Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Seyed Ali
authors.initials: SA
authors.lastname: Nabavizadeh
authors.affiliation: Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
authors.forename: Joel
authors.initials: J
authors.lastname: Stein
authors.affiliation: Department of Radiology, Division of Neuroradiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. Electronic address: Suyash.Mohan@uphs.upenn.edu.
authors.forename: Suyash
authors.initials: S
authors.lastname: Mohan
mesh_terms: D002494:Central Nervous System Infections / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D002561:Cerebrovascular Disorders / Q000000981:diagnostic imaging* / Q000209:etiology / Q000628:therapy; D006801:Humans; D007938:Leukemia / Q000000981:diagnostic imaging* / Q000628:therapy; D008279:Magnetic Resonance Imaging / Q000379:methods*; D059906:Neuroimaging / Q000379:methods*
keywords: CT; Central nervous system; Leukemia; Leukostasis; MRI; Neuroimaging