title: Anagen effluvium secondary toGloriosa superbaingestion.
abstract: Anagen effluvium, the shedding of anagen hair, leads to diffuse non-scarring alopecia. We report two cases of anagen effluvium in the same family secondary to the ingestion of tubers of Gloriosa superba, which contains the antimitotic alkaloid colchicine. Both patients developed anagen effluvium and gastroenteritis 1-2 weeks after consuming the tubers. In addition, one of them had bicytopenia, pleural effusion, hematuria and altered liver function tests. Both were managed conservatively and counseled regarding the reversible nature of the hair loss. Follow-up at 3 months showed regrowth of hair in both the cases.
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
authors.forename: Anupama
authors.initials: A
authors.lastname: Bains
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
authors.forename: G K
authors.initials: GK
authors.lastname: Verma
authors.affiliation: Department of Pathology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
authors.forename: Deepak
authors.initials: D
authors.lastname: Vedant
authors.affiliation: Department of Dermatology, Venereology and Leprosy, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.
authors.forename: Ajeet
authors.initials: A
authors.lastname: Negi
mesh_terms: D000505:Alopecia / Q000139:chemically induced* / Q000175:diagnosis*; D003078:Colchicine / Q000009:adverse effects; D005260:Female; D006197:Hair / Q000187:drug effects* / Q000254:growth & development*; D006801:Humans; D008297:Male; D028321:Plant Preparations / Q000008:administration & dosage / Q000009:adverse effects*; D018517:Plant Roots / Q000009:adverse effects*; D055815:Young Adult
chemical_list: D028321:Plant Preparations; D003078:Colchicine