title: A Case of Erythroderma Secondary to Hypereosinophilia.
abstract: Hypereosinophilic syndrome (HES) is a myeloproliferative disorder characterised by marked peripheral eosinophilia and end organ damage attributable to eosinophilia without secondary cause. Early recognition and treatment are essential to prevent morbidity and mortality. Cytoreduction with Steroids, Hydroxyurea and Imatinib are the main stay of treatment. Molecular studies like Fip1-like-1 fused with platelet derived growth factor receptor alpha (FIP1L1-PDGFRα) etc., are recommended in view of therapeutic implication. In this paper we report a rare case of HES developing in a lady 6 months after surgical removal of lymphangioma of spleen, which in itself is rare.
authors.affiliation: Post Graduate Student, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India .
authors.forename: Mohammed Shafi
authors.initials: MS
authors.lastname: Abdulsalam
authors.affiliation: Associate Consultant Physician, Department of Internal Medicine, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India .
authors.forename: Hari Chandana
authors.initials: HC
authors.lastname: Ghanta
authors.affiliation: Consultant Haematologist, Department of Haematology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India .
authors.forename: Prabu
authors.initials: P
authors.lastname: Pandurangan
authors.affiliation: Senior Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India .
authors.forename: Maya
authors.initials: M
authors.lastname: Menon
authors.affiliation: Consultant Pathologist, Department of Pathology, Greams Road, Apollo Main Hospital , Chennai, Tamil Nadu, India .
authors.forename: Sheba S K
authors.initials: SS
authors.lastname: Jacob
keywords: Adrenal insufficiency; Cytoreduction; Lymphangioma of spleen; Tissue eosinophilia