title: Consensual ophthalmotonic reaction in Chinese patients following augmented trabeculectomy or ExPRESS shunt implantation.
abstract: BACKGROUND
  Consensual ophthalmotonic reaction (COR) was first described in 1924. Studies following monocular application of glaucoma drops and laser trabeculoplasty showed a drop in fellow eye intraocular pressure (IOP). However, studies following monocular surgery showed heterogeneous results. The purpose of this study was to investigate the COR in Chinese patients who have received monocular filtration surgery.
  
  
  METHODS
  A noncomparative retrospective study of 65 eyes undergoing filtration surgery in Queen Mary Hospital was conducted. The IOP was obtained at baseline and postoperative days 1, 3, 7 and 14. Patient's age, sex, type of glaucoma and surgery, preoperative medications, postoperative bleb status, and number of interventions were tabulated. The postoperative IOP measurements over both eyes were obtained, and the readings were averaged to decrease the chances of extreme readings being a one-off event and allow for regression to the mean bias.
  
  
  RESULTS
  COR was observed in the unoperated fellow eye. The mean preoperative IOP and averaged postoperative IOP were 17.2 ± 5.2 mm Hg and 20.1 ± 8.9 mm Hg, respectively (P < 0.04). All medications were continued in the fellow eye or even stepped up. Twenty-three percent of patients demonstrated fellow eye IOP rise >30% from baseline, while none showed IOP drop >30% from baseline.
  
  
  CONCLUSIONS
  Following monocular penetrating filtration surgery, our Chinese population demonstrated a significant fellow eye IOP increase in the early postoperative period. We should bear in mind the influence of COR and take care to measure the fellow eye IOP following monocular surgery.
authors.affiliation: Department of Ophthalmology, the University of Hong Kong, Hong Kong Department of Ophthalmology, Queen Mary Hospital, Hong Kong.
authors.forename: Jennifer W H
authors.initials: JWH
authors.lastname: Shum
authors.forename: Bonnie N K
authors.initials: BNK
authors.lastname: Choy
authors.forename: Wing Lau
authors.initials: WL
authors.lastname: Ho
authors.forename: Jonathan C H
authors.initials: JCH
authors.lastname: Chan
authors.forename: Jimmy S M
authors.initials: JSM
authors.lastname: Lai
mesh_terms: D005260:Female; D005901:Glaucoma / Q000601:surgery*; D006723:Hong Kong; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D011184:Postoperative Period; D012189:Retrospective Studies; D014130:Trabeculectomy / Q000379:methods*