title: RNA Matchmaking: Finding Cellular Pairing Partners.
abstract: RNA structure is intimately related to function, yet methods to identify base-paired RNA strands in a transcriptome-wide manner in cells have remained elusive. One recent paper in Cell and two in Molecular Cell describe related methods to identify RNA sequences that interact in living cells, setting the stage for breakthroughs in our understanding of RNA structure and function.
authors.affiliation: Department of Genetics and Genome Sciences, Institute for Systems Genomics, UConn Health, 400 Farmington Avenue, Farmington, CT 06030, USA. Electronic address: graveley@uchc.edu.
authors.forename: Brenton R
authors.initials: BR
authors.lastname: Graveley
mesh_terms: D000818:Animals; D020029:Base Pairing; D006801:Humans; D009690:Nucleic Acid Conformation; D012313:RNA / Q000737:chemistry* / Q000378:metabolism; D013329:Structure-Activity Relationship
chemical_list: D012313:RNA