title: [Unintended rechallenge : Generalized bullous fixed drug eruption in two elderly women].
abstract: Severe bullous skin reactions like Stevens-Johnson syndrome (SJS), toxic epidermal necrolysis (TEN) and generalized bullous fixed drug eruption (GBFDE) are rare, but occasionally fatal diseases which are mainly induced by drugs. We report about 2 women who both developed severe bullous skin reactions after domestic falls. Despite knowing the causative drug and having an allergy identification, both patients suffered from a secondary event after unintentional re-exposure.
authors.affiliation: Dokumentationszentrum schwerer Hautreaktionen, Universitätsklinikum Freiburg, Hauptstr. 7, 79104, Freiburg, Deutschland. dzh@uniklinik-freiburg.de.
authors.forename: M
authors.initials: M
authors.lastname: Paulmann
authors.affiliation: Dokumentationszentrum schwerer Hautreaktionen, Universitätsklinikum Freiburg, Hauptstr. 7, 79104, Freiburg, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Mockenhaupt
mesh_terms: D000058:Accidental Falls; D000369:Aged, 80 and over; D003937:Diagnosis, Differential; D003875:Drug Eruptions / Q000175:diagnosis* / Q000209:etiology / Q000628:therapy; D006801:Humans; D010328:Patch Tests / Q000379:methods*; D012872:Skin Diseases, Vesiculobullous / Q000139:chemically induced* / Q000175:diagnosis* / Q000628:therapy; D016896:Treatment Outcome
keywords: Blister; Patch test; Recurrence; Stevens–Johnson syndrome; Toxic epidermal necrolysis