title: Neurologic Manifestations of Blood Dyscrasias.
abstract: Neurologic manifestations are common in blood diseases, and they can be caused by the hematologic disorder or its treatment. This article discusses hematologic diseases in adult patients, and categorizes them into benign and malignant conditions. The more common benign hematologic diseases associated with neurologic manifestations include anemias, particularly caused by B12 deficiency and sickle cell disease, and a variety of disorders of hemostasis causing bleeding or thrombosis, including thrombotic microangiopathy. Malignant conditions like multiple myeloma, leukemias, and lymphomas can have neurologic complications resulting from direct involvement, or caused by the different therapies to treat these cancers.
authors.affiliation: Blood and Marrow Transplantation Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA. Electronic address: Daniel.Couriel@hci.utah.edu.
authors.forename: Daniel R
authors.initials: DR
authors.lastname: Couriel
authors.affiliation: Blood and Marrow Transplantation Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.
authors.forename: Holly
authors.initials: H
authors.lastname: Ricker
authors.affiliation: Blood and Marrow Transplantation Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.
authors.forename: Mary
authors.initials: M
authors.lastname: Steinbach
authors.affiliation: Blood and Marrow Transplantation Program, Huntsman Cancer Institute, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.
authors.forename: Catherine J
authors.initials: CJ
authors.lastname: Lee
mesh_terms: D000328:Adult; D000755:Anemia, Sickle Cell / Q000150:complications / Q000628:therapy; D006801:Humans; D007938:Leukemia / Q000628:therapy*; D008223:Lymphoma / Q000628:therapy*; D009101:Multiple Myeloma / Q000628:therapy*; D009422:Nervous System Diseases / Q000209:etiology / Q000628:therapy; D057049:Thrombotic Microangiopathies / Q000150:complications / Q000628:therapy; D014806:Vitamin B 12 Deficiency / Q000150:complications / Q000628:therapy
keywords: Dyscrasia; Myeloma; Neuropathy; Plasma cell; Radiculopathy