title: Gold(I)-Catalyzed Domino Cyclizations of Diynes for the Synthesis of Functionalized Cyclohexenone Derivatives. Total Synthesis of (-)-Gabosine H and (-)-6-epi-Gabosine H.
abstract: 1,6-Diynes with a t-butylcarbonate group in the propargylic position undergo gold(I)-catalyzed domino-cyclization which affords α-hydroxycyclohexenones. The described sequence can be applied on functionalized, highly oxygenated substrates, as examplified in the synthesis of (-)-gabosine H and its epimer.
authors.affiliation: Faculty of Chemistry, University of Belgrade , Studentski trg 16, P.O. Box 51, 11158 Belgrade, Serbia.
authors.forename: Bojan
authors.initials: B
authors.lastname: Vulovic
authors.affiliation: Faculty of Chemistry, University of Belgrade , Studentski trg 16, P.O. Box 51, 11158 Belgrade, Serbia.
authors.forename: Dusan
authors.initials: D
authors.lastname: Kolarski
authors.affiliation: Faculty of Chemistry, University of Belgrade , Studentski trg 16, P.O. Box 51, 11158 Belgrade, Serbia.
authors.forename: Filip
authors.initials: F
authors.lastname: Bihelovic
authors.affiliation: ICTM Center for Chemistry , Njegoseva 12, 11000 Belgrade, Serbia.
authors.forename: Radomir
authors.initials: R
authors.lastname: Matovic
authors.affiliation: Faculty of Chemistry, University of Belgrade , Studentski trg 16, P.O. Box 51, 11158 Belgrade, Serbia.
authors.forename: Maja
authors.initials: M
authors.lastname: Gruden
authors.affiliation: Faculty of Chemistry, University of Belgrade , Studentski trg 16, P.O. Box 51, 11158 Belgrade, Serbia.
authors.forename: Radomir N
authors.initials: RN
authors.lastname: Saicic