title: Single Dose of Levofloxacin versus Three Dosages for Prophylaxis in Prostate Biopsy.
abstract: Transrectal ultrasound-guided core prostate biopsy is a key event in the diagnosis of prostate cancer, transient side events such as local pain, haematuria, haematospermia, dysuria, and rectal bleeding are reported in a large number of patients. Antimicrobial agents lower the incidence of postbiopsy infectious complications. The timing and duration of the regimen and the route of administration remain controversial. We developed a standard prophylactic regimen, in which safety and efficiency were maximized, while costs and variability were minimized. Accordingly we prospectively evaluated 425 consecutive patients, who underwent outpatient transrectal ultrasound-guided prostate biopsy after a single dose versus three doses of levofloxacin.
authors.affiliation: Urology Department, Centro Medico Nacional "20 de Noviembre" México, Félix Cuevas 540, Del Valle, Benito Juárez, 03100 Ciudad de México, DF, Mexico.
authors.forename: Edgar
authors.initials: E
authors.lastname: Linden-Castro
authors.affiliation: Urology Department, Centro Medico Nacional "20 de Noviembre" México, Félix Cuevas 540, Del Valle, Benito Juárez, 03100 Ciudad de México, DF, Mexico.
authors.forename: Marcela
authors.initials: M
authors.lastname: Pelayo-Nieto
authors.affiliation: Urology Department, Centro Medico Nacional "20 de Noviembre" México, Félix Cuevas 540, Del Valle, Benito Juárez, 03100 Ciudad de México, DF, Mexico.
authors.forename: Alejandro
authors.initials: A
authors.lastname: Alias-Melgar
authors.affiliation: Urology Department, Centro Medico Nacional "20 de Noviembre" México, Félix Cuevas 540, Del Valle, Benito Juárez, 03100 Ciudad de México, DF, Mexico.
authors.forename: Fernando
authors.initials: F
authors.lastname: Carreño-de la Rosa