title: Gait Parameters and Functional Outcomes After Total Knee Arthroplasty Using Persona Knee System With Cruciate Retaining and Ultracongruent Knee Inserts.
abstract: Total knee arthroplasty is a well-established treatment for managing end-stage symptomatic knee osteoarthritis. Currently, different designs of prostheses are available with majority ensuring similar clinical outcomes. Altered surface geometry is introduced to strive toward gaining superior outcomes. We aimed to investigate any differences in functional outcomes between 2 different polyethylene designs namely the Persona CR (cruciate retaining) and Persona UC (ultracongruent) tibial inserts (Zimmer-Biomet, Warsaw, IN).
  
  
  
  This prospective single blind, single-surgeon randomized controlled trial reports on 105 patients, (66 female and 39 male), who underwent simultaneous bilateral total knee arthroplasty using the Persona knee system (Zimmer-Biomet) UC inserts in one side and CR inserts in the contralateral side. By a blind assessor, at regular time intervals patients were assessed in terms of function and gait. The functional knee scoring scales used were the Western Ontario and McMaster Universities Osteoarthritis Index and Modified Knee Society Score. The gait parameters evaluated were foot pressure and step length.
  
  
  
  During the study period, no patient was lost to follow-up or underwent revision surgery for any cause. Western Ontario and McMaster Universities Osteoarthritis Index scores, Modified Knee Society Score, and knee range of motion of all 105 patients assessed preoperatively and postoperatively at 6 months, 1 year, and 2 years showed statistically better results (P < .05) for UC inserts. Gait analysis measuring foot pressures and step length, however, did not show any statistically significant differences at 2-year follow-up.
  
  
  
  Ultracongruent tibial inserts show significantly better functional outcomes as compared to CR inserts during a 2-year follow-up period. However, in this study these findings were not shown to be attributed to differences in gait parameters.
authors.affiliation: Medanta Bone and Joint Institute, Medanta-The Medicity, Gurgaon, Haryana, India.
authors.forename: Ashok
authors.initials: A
authors.lastname: Rajgopal
authors.affiliation: Medanta Bone and Joint Institute, Medanta-The Medicity, Gurgaon, Haryana, India.
authors.forename: Kalpana
authors.initials: K
authors.lastname: Aggarwal
authors.affiliation: Medanta Bone and Joint Institute, Medanta-The Medicity, Gurgaon, Haryana, India.
authors.forename: Anshika
authors.initials: A
authors.lastname: Khurana
authors.affiliation: Medanta Bone and Joint Institute, Medanta-The Medicity, Gurgaon, Haryana, India.
authors.forename: Arun
authors.initials: A
authors.lastname: Rao
authors.affiliation: Medanta Bone and Joint Institute, Medanta-The Medicity, Gurgaon, Haryana, India.
authors.forename: Attique
authors.initials: A
authors.lastname: Vasdev
authors.affiliation: Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford, Oxford, United Kingdom.
authors.forename: Hemant
authors.initials: H
authors.lastname: Pandit
mesh_terms: D000368:Aged; D019645:Arthroplasty, Replacement, Knee / Q000379:methods*; D005260:Female; D005684:Gait; D006801:Humans; D007719:Knee Joint / Q000601:surgery; D007720:Knee Prosthesis; D008297:Male; D008875:Middle Aged; D020370:Osteoarthritis, Knee / Q000601:surgery*; D020959:Polyethylene; D011184:Postoperative Period; D011312:Pressure; D011446:Prospective Studies; D011474:Prosthesis Design; D016059:Range of Motion, Articular; D012086:Reoperation; D016037:Single-Blind Method
chemical_list: D020959:Polyethylene
keywords: Modified Knee Society Score (MKSS); Persona cruciate retaining (CR); Persona ultracongruent (UC); Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC); total knee arthroplasty (TKA)