title: A Case of Recurrent Hepatocellular Carcinoma Acquiring Complete Remission of Target Lesion With Treatment With Traditional Chinese Medicine.
abstract: Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies worldwide. Although surgery is known as the most promising radical treatment, a high recurrent or metastatic rate after surgery has limited its clinical efficacy. Sorafenib, a target agent, has seemed to be the only option for metastatic HCC patients to date, but none of clinical trials showed it could prolong the overall survival (OS) of advanced HCC to 1 year. How to prolong the OS and improve cure rate of HCC patients is still beset with difficulties. This report presents a rare case of recurrent HCC patient with complete regression of target lesion with 2 years of Chinese herbal treatment. A 64-year-old Chinese man with hepatitis B virus-associated chronic hepatitis presented HCC has been clinically diagnosed tumor relapse and omentum metastasis with computed tomography and α-fetoprotein blood test 4 months after surgery. It was decided the patient would receive traditional Chinese medicine treatment because of poor prognosis. After approximately 2 years of treatment, recurrent hepatic tumor and omentum metastasis have been found in complete regression. The patient remains alive over 31 months after relapse.
authors.affiliation: 1 Quzhou People's Hospital, Zhejiang, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Jianxin
authors.affiliation: 1 Quzhou People's Hospital, Zhejiang, China.
authors.forename: Xu
authors.initials: X
authors.lastname: Qingxia
authors.affiliation: 2 Department of Radiation Oncology, Quzhou People's Hospital, Zhejiang, China.
authors.forename: Wang
authors.initials: W
authors.lastname: Junhui
authors.affiliation: 1 Quzhou People's Hospital, Zhejiang, China.
authors.forename: Zheng
authors.initials: Z
authors.lastname: Qinhong
mesh_terms: D000970:Antineoplastic Agents / Q000627:therapeutic use*; D006528:Carcinoma, Hepatocellular / Q000188:drug therapy*; D004365:Drugs, Chinese Herbal / Q000627:therapeutic use*; D006801:Humans; D008113:Liver Neoplasms / Q000188:drug therapy*; D008297:Male; D008516:Medicine, Chinese Traditional / Q000379:methods; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000188:drug therapy*; D012074:Remission Induction / Q000379:methods
chemical_list: D000970:Antineoplastic Agents; D004365:Drugs, Chinese Herbal
keywords: activities; complete remission; recurrent hepatocellular carcinoma; spontaneous regression; traditional Chinese medicine