title: Ovarian and tubal cancer in Denmark: an update on incidence and survival.
abstract: BACKGROUND
  The Nordic countries are areas with a high-incidence of ovarian cancer; however, differences between the countries exist.
  
  
  METHODS
  We used the Danish Cancer Registry to identify 11 264 cases of ovarian cancer and 363 cases of tubal cancer during 1993-2013. We calculated age-standardized (world standard population) incidence rates for overall and subtype-specific ovarian cancer, and for tubal cancer. We compared age-standardized incidence rates, and 1- and 5-year age-standardized relative survival rates, respectively, for ovarian and tubal cancer combined in four Nordic countries using the NORDCAN database.
  
  
  RESULTS
  The incidence rate of ovarian cancer overall in Denmark decreased statistically significantly by approximately 2.3% per year among women aged <70 years, whereas no change was seen among women aged 70+ years. In the <70-year age-group, the incidence of serous tumors was fairly steady, whereas that of other and unspecified epithelial tumors decreased significantly by 6.4% per year. The incidence of tubal cancer was quite stable. In Norway and Finland, the incidence rates of ovarian and tubal cancer combined decreased from 1993 to 2013 in women aged <70 years, whereas in Sweden the incidence rates decreased independently of age. The 1- and 5-year relative survival rates of ovarian and tubal cancer combined increased during the study period in all the Nordic countries. Denmark had the lowest survival; however, the survival rates approached those of the other countries in recent years.
  
  
  CONCLUSIONS
  In Denmark, the positive development in ovarian cancer has continued during recent years with a lower incidence and an increased survival.
authors.affiliation: Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Mathilde
authors.identifier: http://orcid.org/0000-0002-3524-2646
authors.initials: M
authors.lastname: Gottschau
authors.affiliation: Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark. lene@cancer.dk.
authors.forename: Lene
authors.initials: L
authors.lastname: Mellemkjaer
authors.affiliation: Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.
authors.forename: Charlotte G
authors.initials: CG
authors.lastname: Hannibal
authors.affiliation: Virus, Lifestyle and Genes, Danish Cancer Society Research Center, Copenhagen, Denmark.|Department of Gynecology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Susanne K
authors.initials: SK
authors.lastname: Kjaer
mesh_terms: D000328:Adult; D017677:Age Distribution; D000368:Aged; D000369:Aged, 80 and over; D003718:Denmark / Q000453:epidemiology; D005185:Fallopian Tube Neoplasms / Q000453:epidemiology*; D005187:Fallopian Tubes; D005260:Female; D006801:Humans; D008875:Middle Aged; D009367:Neoplasm Staging; D010051:Ovarian Neoplasms / Q000453:epidemiology*; D012307:Risk Factors; D012537:Scandinavian and Nordic Countries / Q000453:epidemiology; D016019:Survival Analysis; D017741:Survivors / Q000706:statistics & numerical data*; D013548:Sweden / Q000453:epidemiology
keywords: Epidemiology; fallopian tube cancer; incidence; ovarian cancer; survival