title: Predictors of Depressive Mood in Patients With Isolated Cerebellar Stroke: A Retrospective Study.
abstract: OBJECTIVE
  To identify predictive factors of depressive mood in patients with isolated cerebellar stroke.
  
  
  METHODS
  A retrospective chart review was performed in patients who had experienced their first isolated cerebellar stroke during 2002-2014. The patients were classified into two groups by the Geriatric Depression Scale (GDS) (non-depressive group, 0≤GDS≤16; depressive group, 17≤GDS≤30). Data on demographic and socioeconomic factors, comorbidities, functional level, cognitive and linguistic function, and stroke characteristics were collected. Significant variables in univariate analysis were analyzed using logistic regression.
  
  
  RESULTS
  Fifty-two patients were enrolled, of whom 55.8% had depressive mood, were older (p=0.021), and had higher hypertension rates (p=0.014). Cognitive and linguistic functions did not differ between the two groups. The depressive group had higher ischemic stroke rates (p=0.035) and showed a dominant right posterior cerebellar hemisphere lesion (p=0.028), which was independently associated with depressive mood in the multiple logistic regression analysis (odds ratio, 5.081; 95% confidence interval, 1.261-20.479).
  
  
  CONCLUSIONS
  The risk of depressive mood after cerebellar stroke was increased in patients at old age, with a history of hypertension, ischemic stroke, and lesion of the right posterior cerebellar hemisphere. The most significant determining factor was stroke lesion of the right posterior cerebellar hemisphere. Early detection of risk factors is important to prevent and manage depressive mood after cerebellar stroke.
authors.affiliation: Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine & Severance Hospital, Seoul, Korea.
authors.forename: Dong Jin
authors.identifier: 0000-0001-5673-3068
authors.initials: DJ
authors.lastname: Koh
authors.affiliation: Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine & Severance Hospital, Seoul, Korea.
authors.forename: Na Young
authors.identifier: 0000-0001-9888-3953
authors.initials: NY
authors.lastname: Kim
authors.affiliation: Department of Rehabilitation Medicine and Research Institute of Rehabilitation Medicine, Yonsei University College of Medicine & Severance Hospital, Seoul, Korea.
authors.forename: Yong Wook
authors.identifier: 0000-0002-5234-2454
authors.initials: YW
authors.lastname: Kim
keywords: Cerebellum; Depression; Risk factors; Stroke