title: Topology simplification: Important biological phenomenon or evolutionary relic?: Comment on "Disentangling DNA molecules" by Alexander Vologodskii.
authors.affiliation: Institute of Integrative Biology, University of Liverpool, Crown Street, Liverpool L69 7ZB, UK. Electronic address: bates@liverpool.ac.uk.
authors.forename: Andrew D
authors.initials: AD
authors.lastname: Bates
authors.affiliation: Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, UK.
authors.forename: Anthony
authors.initials: A
authors.lastname: Maxwell
mesh_terms: D005075:Biological Evolution; D004247:DNA; D009690:Nucleic Acid Conformation
chemical_list: D004247:DNA