title: The Role of Serum Bilirubin Levels in Predicting Troponin Positivity in Non-ST-Segment Elevation Acute Coronary Syndrome.
abstract: Data are scant regarding serum bilirubin levels in non-ST-segment elevation acute coronary syndrome (NSTE-ACS). In this study, we evaluated the role of serum bilirubin levels in NSTE-ACS. We enrolled 782 patients who presented to the emergency department with acute chest pain. Patients were divided into 2 groups based on the troponin positivity. Patients with NSTE-ACS who had troponin positivity were included in group 1 (n = 382), and group 2 consisted of the control patients (n = 400). Direct bilirubin (DB) levels (group 1: 0.31 ± 0.37 mg/dL, group 2: 0.20 ± 0.25 mg/dL, P < .001) and total bilirubin (TB) levels (group 1: 0.78 ± 0.56 mg/dL, group 2: 0.62 ± 0.45 mg/dL, P < .001) were significantly higher in group 1. There was a significant and moderate correlation between serum bilirubin levels and admission troponin values ( r = .34, P < .001 for TB and r = .42, P < .001 for DB). These results show that serum bilirubin levels were associated with troponin positivity in patients with NSTE-ACS.
authors.affiliation: 1 Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Ozturk
authors.affiliation: 2 Department of Cardiology, Palandoken State Hospital, Erzurum, Turkey.
authors.forename: Lutfu
authors.initials: L
authors.lastname: Askın
authors.affiliation: 1 Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Ipek
authors.affiliation: 1 Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Selami
authors.initials: S
authors.lastname: Demirelli
authors.affiliation: 3 Department of Cardiology, Aydın State Hospital, Aydın, Turkey.
authors.forename: Oguzhan Ekrem
authors.initials: OE
authors.lastname: Turan
authors.affiliation: 1 Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Erkan
authors.initials: E
authors.lastname: Yıldırım
authors.affiliation: 1 Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Emrah
authors.initials: E
authors.lastname: Ermis
authors.affiliation: 1 Department of Cardiology, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Kamuran
authors.initials: K
authors.lastname: Kalkan
authors.affiliation: 4 Department of Emergency Medicine, Erzurum Education and Research Hospital, Erzurum, Turkey.
authors.forename: Orhan
authors.initials: O
authors.lastname: Delice
mesh_terms: D054058:Acute Coronary Syndrome / Q000097:blood*; D001663:Bilirubin / Q000097:blood*; D015415:Biomarkers / Q000097:blood; D002637:Chest Pain / Q000097:blood*; D004562:Electrocardiography; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000097:blood*; D011237:Predictive Value of Tests; D012307:Risk Factors; D014336:Troponin / Q000097:blood*
chemical_list: D015415:Biomarkers; D014336:Troponin; D001663:Bilirubin
keywords: bilirubin; non-segment ST elevation acute coronary syndrome; troponin