title: Successful delivery after surgical repair of uterine rupture at 15 weeks of gestation: case report and brief review.
abstract: OBJECTIVE
  Second-trimester uterine rupture is a rare disorder and it is unclear if it should be managed with caesarean section, repair or hysterectomy. This article provides a case report of second-trimester uterine rupture repair, and reviews the risk factors, signs and symptoms, suturing technique and newborn outcome.
  
  
  METHODS
  PubMed was searched using the terms 'uterine rupture', 'second trimester' and 'repair' Only cases of second-trimester uterine rupture repair that led to successful prolongation of pregnancy were included.
  
  
  RESULTS
  The main risk factor of uterine rupture is previous caesarean section (5/10, 50%). Eight of 10 cases presented with abdominal pain and three cases presented in shock. Haemoperitoneum was present in five cases. The mean and median gestational age at delivery were 33.4 and 33.5 weeks, respectively (range 28-37 weeks), with mean and median delayed interval delivery of 95.5 and 91 days, respectively (range 14-147 days). Neonatal outcome was good for 10 of 11 newborns. Despite the early onset of uterine rupture, there were no cases of extremely preterm delivery. One early preterm infant, seven moderate-to-late preterm infants and one term infant were delivered.
  
  
  CONCLUSIONS
  The lack of extremely preterm deliveries and good neonatal outcomes encourage attempts to repair the uterus after second-trimester rupture.
authors.affiliation: Department of Obstetrics and Gynaecology, University of Eastern Piedmont, Novara, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Surico
authors.affiliation: Department of Obstetrics and Gynaecology, University of Eastern Piedmont, Novara, Italy. Electronic address: ierama@tin.it.
authors.forename: R
authors.initials: R
authors.lastname: Amadori
authors.affiliation: Department of Obstetrics and Gynaecology, University of Eastern Piedmont, Novara, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Vigone
authors.affiliation: Department of Obstetrics and Gynaecology, University of Eastern Piedmont, Novara, Italy.
authors.forename: C
authors.initials: C
authors.lastname: D'Agostino
authors.affiliation: Department of Surgical, Microsurgical and Medical Sciences, Gynaecologic and Obstetric Clinic, University of Sassari, Sassari, Italy.
authors.forename: M
authors.initials: M
authors.lastname: Dessole
authors.affiliation: Department of Obstetrics and Gynaecology, University of Eastern Piedmont, Novara, Italy.
authors.forename: N
authors.initials: N
authors.lastname: Surico
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D011247:Pregnancy; D011248:Pregnancy Complications / Q000601:surgery*; D011256:Pregnancy Outcome; D011262:Pregnancy Trimester, Second; D016896:Treatment Outcome; D014597:Uterine Rupture / Q000601:surgery*
keywords: Haemoperitoneum in pregnancy; Midtrimester uterine rupture; Uterine repair in pregnancy; Uterine rupture in pregnancy; Uterine scar in pregnancy