title: Identification of informative bands in the short-wavelength NIR region for non-invasive blood glucose measurement.
abstract: The "glucose-linked wavelength" in the short-wavelength near-infrared (NIR) region, in which the light intensity reflected from the hand palm exhibits a good correlation to the blood glucose value, was investigated. We performed 391 2-h carbohydrate tolerance tests (CTTs) using 34 participants and a glucose-linked wavelength was successfully observed in almost every CTT; however, this wavelength varied between CTTs even for the same person. The large resulting data set revealed the distribution of the informative wavelength. The blood glucose values were efficiently estimated by a simple linear regression with clinically acceptable accuracies. The result suggested the potential for constructing a personalized low-invasive blood glucose sensor using short-wavelength NIR spectroscopy.
authors.affiliation: Analytical Science Division, Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba 305-8642, Japan.
authors.forename: Yasuhiro
authors.initials: Y
authors.lastname: Uwadaira
authors.affiliation: Analytical Science Division, Food Research Institute, NARO, 2-1-12 Kannondai, Tsukuba 305-8642, Japan.
authors.forename: Akifumi
authors.initials: A
authors.lastname: Ikehata
authors.affiliation: Food and Cookery Sciences, Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado 350-0288, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Momose
authors.affiliation: Food and Cookery Sciences, Kagawa Nutrition University, 3-9-21 Chiyoda, Sakado 350-0288, Japan.
authors.forename: Masayo
authors.initials: M
authors.lastname: Miura
keywords: (170.1470) Blood or tissue constituent monitoring; (170.3890) Medical optics instrumentation; (300.1030) Absorption; (300.6340) Spectroscopy, infrared