title: Acute lymphocytic leukemia presenting as a single brain mass.
abstract: Hematologic malignancies most commonly spread to the central nervous system via leptomeningeal infiltration. We present a unique case of a woman who presented with a right parietal mass as the initial manifestation of B cell acute lymphocytic leukemia. Because the diagnosis was unclear at the time of presentation she underwent surgical debulking of the mass prior to treatment with chemotherapy. Unfortunately, she relapsed several months after treatment and ultimately entered hospice care. We review the literature surrounding management considerations in patients with intracranial leukemic involvement.
authors.affiliation: Department of Neurosurgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. Electronic address: Sbick@partners.org.
authors.forename: Sarah K B
authors.initials: SK
authors.lastname: Bick
authors.affiliation: Department of Neurosurgery, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA.
authors.forename: Navid
authors.initials: N
authors.lastname: Redjal
mesh_terms: D001932:Brain Neoplasms / Q000556:secondary* / Q000601:surgery; D019468:Disease Management; D005260:Female; D006801:Humans; D008875:Middle Aged; D010296:Parietal Lobe / Q000473:pathology* / Q000601:surgery; D054198:Precursor Cell Lymphoblastic Leukemia-Lymphoma / Q000473:pathology* / Q000601:surgery
keywords: Brain mass; Intracranial leukemic deposit; Leukemia