title: An AIE-active fluorescence turn-on bioprobe mediated by hydrogen-bonding interaction for highly sensitive detection of hydrogen peroxide and glucose.
abstract: An AIE-active "turn-on" bioprobe is designed for hydrogen peroxide detection based on an imine-functionalized tetraphenylethene derivative. The linear fluorescence response enables quantification of hydrogen peroxide with superior sensitivity and selectivity. Meanwhile, glucose assay is also realized by taking advantage of GOx/glucose enzymatic reaction.
authors.affiliation: Department of Chemistry, Hong Kong Branch of Chinese National Engineering Research Center for Tissue Restoration and Reconstruction, Institute for Advanced Study, Division of Biomedical Engineering, Division of Life Science, State Key Laboratory of Molecular Neuroscience and Institute of Molecular Functional Materials, The Hong Kong University of Science and Technology, Clear Water Bay, Kowloon, Hong Kong, China. tangbenz@ust.hk.
authors.forename: Zhegang
authors.initials: Z
authors.lastname: Song
authors.forename: Ryan T K
authors.initials: RT
authors.lastname: Kwok
authors.forename: Dan
authors.initials: D
authors.lastname: Ding
authors.forename: Han
authors.initials: H
authors.lastname: Nie
authors.forename: Jacky W Y
authors.initials: JW
authors.lastname: Lam
authors.forename: Bin
authors.initials: B
authors.lastname: Liu
authors.forename: Ben Zhong
authors.initials: BZ
authors.lastname: Tang
mesh_terms: D015374:Biosensing Techniques; D005453:Fluorescence; D005456:Fluorescent Dyes / Q000737:chemistry*; D005947:Glucose / Q000032:analysis*; D006860:Hydrogen Bonding; D006861:Hydrogen Peroxide / Q000032:analysis*; D015394:Molecular Structure
chemical_list: D005456:Fluorescent Dyes; D006861:Hydrogen Peroxide; D005947:Glucose