title: Cancer Therapeutic Resistance: Progress and Perspectives (April 7-8, 2016 - Barcelona, Spain).
abstract: At the Cancer Therapeutic Resistance: Progress and Perspectives conference, in Barcelona, Spain, April 7-8, 2016, researchers, clinicians and students gathered to discuss our current understanding of intrinsic and acquired resistance of tumors to cancer therapies and to explore how to translate strategies to predict risk or overcome resistance to the clinic. The sessions covered a wide range of topics, including cancer omics, molecular classification, clinically relevant tumor models, biomarkers and novel therapeutic targets, and personalized medicine, with talks from many international experts in the field. This report highlights the main presentations that demonstrate the progress being made in predicting and identifying drug resistance in patients with cancer, personalized approaches to direct treatment and understanding the mechanisms involved. With better models of human cancer and powerful high-throughput screening techniques, translation to the clinic leading to tangible benefits for patients is attainable.
authors.affiliation: Freelance medical and science writer, on behalf of Vall d'Hebron Institute of Oncology (VHIO), Centro Cellex, Barcelona, Spain. ezzie_h@hotmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Hutchinson
authors.affiliation: Program Against Cancer Therapeutic Resistance (ProCURE), Catalan Institute of Oncology (ICO), Bellvitge Institute for Biomedical Research (IDIBELL), L'Hospitalet del Llobregat,Barcelona, Spain.
authors.forename: M A
authors.initials: MA
authors.lastname: Pujana
authors.affiliation: Preclinical Research Program, VHIO, Barcelona, Spain.
authors.forename: J
authors.initials: J
authors.lastname: Arribas
mesh_terms: D019008:Drug Resistance, Neoplasm; D006801:Humans; D058990:Molecular Targeted Therapy; D009369:Neoplasms / Q000188:drug therapy*; D057285:Precision Medicine
keywords: Biomarkers; Cancer therapy; Drug resistance; Personalized medicine; Signaling pathways