title: Cell Proliferation on Macro/Nano Surface Structure and Collagen Immobilization of 3D Polycaprolactone Scaffolds.
abstract: In this study, 3D polycaprolactone (PCL) scaffolds were fabricated by 3D printing technique. The macro/nano morphology of, 3D PCL scaffolds surface was etched with oxygen plasma. Acrylic acid (AA) plasma-polymerization was performed to functionalize the macro/nano surface with carboxyl groups and then collagen was immobilized with plasma-polymerized 3D PCL scaffolds. After O2 plasma and AA plasma-polymerization, contact angles were decreased. The FE-SEM and AFM results showed that O2 plasma is increased the surface roughness. The MTT assay results showed that proliferation of the M3CT3-E1 cells increased on the oxygen plasma treated and collagen immobilized 3D PCL scaffolds.
authors.forename: Young-Ouk
authors.initials: YO
authors.lastname: Park
authors.forename: Sung-Woon
authors.initials: SW
authors.lastname: Myung
authors.forename: Min-Suk
authors.initials: MS
authors.lastname: Kook
authors.forename: Sang-Chul
authors.initials: SC
authors.lastname: Jung
authors.forename: Byung-Hoon
authors.initials: BH
authors.lastname: Kim
mesh_terms: D000818:Animals; D002460:Cell Line; D049109:Cell Proliferation; D003094:Collagen / Q000737:chemistry*; D051379:Mice; D049329:Nanostructures / Q000737:chemistry*; D011076:Polycarboxylate Cement / Q000737:chemistry*; D054457:Tissue Scaffolds / Q000737:chemistry*
chemical_list: D011076:Polycarboxylate Cement; C005506:polycarbonate; D003094:Collagen