title: The clinical course of pain and disability following surgery for spinal stenosis: a systematic review and meta-analysis of cohort studies.
abstract: The aim of this study was to assess the clinical course of pain and disability in patients with lumbar spinal stenosis following surgery.
  
  
  
  Electronic databases were searched to July 2014 and only prospective cohort studies assessing pain or disability following surgery for lumbar spinal stenosis were included. Two independent reviewers extracted data and assessed study quality. Estimates of pain and disability (expressed as 0-100 point scales) as well as 95 % confidence intervals were obtained using meta-regression. The effect of time was clearly non-linear, so it was modelled using fractional polynomial regression.
  
  
  
  From a total of 10,741 titles, 69 publications (64 cohort studies) were included in the review. Pooled estimate for pain pre-operatively was 63.4 (95 % CI 56.5; 70.3), reducing to 33.1 (95 % CI 24.2; 41.9) at 3 months and 19.2 points (95 % CI 9.2; 29.3) at 60 months. Pre-operative estimates of disability were 36.9 (95 % CI 32.6; 41.3), reducing to 16.3 (95 % CI 11.8; 20.9) at 3 months and 12.4 (95 % CI 7.7; 17.2) at 60 months.
  
  
  
  Patients with lumbar spinal stenosis experience rapid symptom reduction after surgery, but should still expect to experience mild-to-moderate pain and disability 60 months later.
authors.affiliation: Discipline of Physiotherapy, Faculty Health Sciences, The University of Sydney, Sydney, Australia. carolinafritsch@gmail.com.|Departamento de Fisioterapia, Universidade Federal de Ciências da Saúde de Porto Alegre, R. Sarmento Leite 245, Porto Alegre, Brazil. carolinafritsch@gmail.com.
authors.forename: Carolina G
authors.identifier: 0000-0001-8052-1495
authors.initials: CG
authors.lastname: Fritsch
authors.affiliation: The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, Australia.|The Institute of Bone and Joint Research, Sydney Medical School, University of Sydney, Sydney, Australia.
authors.forename: Manuela L
authors.initials: ML
authors.lastname: Ferreira
authors.affiliation: The George Institute for Global Health, Sydney Medical School, University of Sydney, Sydney, Australia.
authors.forename: Christopher G
authors.initials: CG
authors.lastname: Maher
authors.affiliation: Neuroscience Research Australia, University of New South Wales, Sydney, Australia.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Herbert
authors.affiliation: Departamento de Fisioterapia, Faculdade de Ciências e Tecnologia, UNESP, Univ Estadual Paulista, Presidente Prudente, Brazil.
authors.forename: Rafael Z
authors.initials: RZ
authors.lastname: Pinto
authors.affiliation: Department of General Practice, Erasmus MC, Rotterdam, The Netherlands.
authors.forename: Bart
authors.initials: B
authors.lastname: Koes
authors.affiliation: Discipline of Physiotherapy, Faculty Health Sciences, The University of Sydney, Sydney, Australia.
authors.forename: Paulo H
authors.initials: PH
authors.lastname: Ferreira
mesh_terms: D004185:Disability Evaluation; D006801:Humans; D008159:Lumbar Vertebrae / Q000601:surgery*; D010147:Pain Measurement; D063868:Patient Outcome Assessment; D011184:Postoperative Period; D013130:Spinal Stenosis / Q000601:surgery*
keywords: Lumbar spinal stenosis; Meta-analysis; Prognosis; Surgery