title: Mapping cortical hand motor representation using TMS: A method to assess brain plasticity and a surrogate marker for recovery of function after stroke?
abstract: Stroke is associated with reorganization within motor areas of both hemispheres. Mapping the cortical hand motor representation using transcranial magnetic stimulation may help to understand the relationship between motor cortex reorganization and motor recovery of the affected hand after stroke.
  
  
  
  A standardized review of the pertinent literature was performed.
  
  
  
  We identified 20 trials, which analyzed the relationship between the extent and/or location of cortical hand motor representation using transcranial magnetic stimulation and motor function and recovery of the affected hand. Several correlations were found between cortical reorganization and measures of hand motor impairment and recovery.
  
  
  
  A better understanding of the relationships between the extent and location of cortical hand motor representation and the motor impairment and motor recovery of the affected hand after stroke may contribute to a targeted use of non-invasive brain stimulation protocols. In the future motor mapping may help to guide brain stimulation techniques to the most effective motor area in an affected individual.
authors.affiliation: HELIOS Klinik Kipfenberg, Kipfenberg, Germany. Electronic address: jpodubec@post.cz.
authors.forename: Jitka
authors.initials: J
authors.lastname: Lüdemann-Podubecká
authors.affiliation: HELIOS Klinik Kipfenberg, Kipfenberg, Germany; Department of Neurology, University Hospital, Philipps-University, Marburg, Germany.
authors.forename: Dennis Alexander
authors.initials: DA
authors.lastname: Nowak
mesh_terms: D015415:Biomarkers; D001921:Brain; D001931:Brain Mapping; D006801:Humans; D020127:Recovery of Function; D020521:Stroke
chemical_list: D015415:Biomarkers
keywords: Cortical hand motor representation; Hand motor recovery; Stroke; Transcranial magnetic stimulation