title: Atypical Rapidly Enlarging Orbital Schwannoma.
abstract: Orbital schwannomas are typically slow-growing benign tumors that can cause gradual loss of vision, proptosis, and limitation of ocular motility. The authors present an atypical case of a rapidly growing orbital apex schwannoma in a patient with preexisting vision loss secondary to presumed sarcoidal optic neuritis. Contrary to the slowly progressive nature of a typical orbital schwannoma, the lesion was observed to enlarge from radiologically undiscernible to 3.5 cm over 4 years.
authors.affiliation: *Department of Ophthalmology, Edward S. Harkness Eye Institute, and †Department of Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, U.S.A.
authors.forename: Kevin K
authors.initials: KK
authors.lastname: Ma
authors.forename: Alison B
authors.initials: AB
authors.lastname: Callahan
authors.forename: Shih-Hsiu J
authors.initials: SJ
authors.lastname: Wang
authors.forename: James E
authors.initials: JE
authors.lastname: Goldman
authors.forename: Michael
authors.initials: M
authors.lastname: Kazim
mesh_terms: D001706:Biopsy; D018450:Disease Progression; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D009442:Neurilemmoma / Q000175:diagnosis*; D009915:Orbit / Q000473:pathology*; D009918:Orbital Neoplasms / Q000175:diagnosis*; D013997:Time Factors