title: Triple semicircular canal plugging: a novel modality for the treatment of intractable Meniere's disease.
abstract: CONCLUSIONS
  TSCP, which can reduce vertiginous symptoms in patients with intractable MD, represents an effective therapy for this disorder.
  
  
  OBJECTIVE
  To explore the long-term efficacy of triple semicircular canal plugging (TSCP) in the treatment of intractable Meniere's disease (MD).
  
  
  METHODS
  Seventy-nine patients diagnosed with unilateral MD referred to a vertigo clinic of the hospital between December 2010 and December 2013 were included in this study for retrospective analysis. TSCP was performed in the affected ear for each patient. Vertigo control and auditory function were measured. Pure tone audiometry, caloric test, and cervical vestibular evoked myogenic potential (cVEMP) were performed in 2-year follow-up. Thirty-six MD patients, who accepted endolymphatic sac decompression (ESD) operation were selected as a comparison group.
  
  
  RESULTS
  The total control rate of vertigo in the TSCP group was 98.7% in the 2-year follow-up, with a complete control rate of 81.0% and substantial control rate of 17.7%. The rate of hearing preservation was 70.9%. The total control rate of vertigo in the ESD operation group was 72.2%. The vertigo control rate of TSCP was significantly higher than that of ESD operation. Twenty-four months after treatment, canal paresis was found in the operation side of all patients of TSCP by means of caloric test.
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , PR China.
authors.forename: Daogong
authors.initials: D
authors.lastname: Zhang
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , PR China.
authors.forename: Zhaomin
authors.initials: Z
authors.lastname: Fan
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , PR China.
authors.forename: Yuechen
authors.initials: Y
authors.lastname: Han
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , PR China.
authors.forename: Yafeng
authors.initials: Y
authors.lastname: Lv
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , PR China.
authors.forename: Yawei
authors.initials: Y
authors.lastname: Li
authors.affiliation: a Department of Otorhinolaryngology-Head and Neck Surgery , Shandong Provincial Hospital Affiliated to Shandong University , Jinan , PR China.|b Shandong Provincial Key Laboratory of Otology , Jinan , PR China.
authors.forename: Haibo
authors.initials: H
authors.lastname: Wang
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D034381:Hearing Loss / Q000209:etiology; D006801:Humans; D008297:Male; D008575:Meniere Disease / Q000601:surgery*; D008875:Middle Aged; D013506:Otologic Surgical Procedures / Q000009:adverse effects / Q000706:statistics & numerical data*; D012189:Retrospective Studies; D012665:Semicircular Canals / Q000601:surgery*
keywords: Meniere’s disease; semicircular canal plugging; vertigo