title: Acute Kidney Injury Predicts Mortality after Charcoal Burning Suicide.
abstract: A paucity of literature exists on risk factors for mortality in charcoal burning suicide. In this observational study, we analyzed the data of 126 patients with charcoal burning suicide that seen between 2002 and 2013. Patients were grouped according to status of renal damage as acute kidney injury (N = 49) or non-acute kidney injury (N = 77). It was found that patients with acute kidney injury suffered severer complications such as respiratory failure (P = 0.002), myocardial injury (P = 0.049), hepatic injury (P < 0.001), rhabdomyolysis (P = 0.045) and out-of-hospital cardiac arrest (P = 0.028) than patients without acute kidney injury. Moreover, patients with acute kidney injury suffered longer hospitalization duration (16.9 ± 18.3 versus 10.7 ± 10.9, P = 0.002) and had higher mortality rate (8.2% versus 0%, P = 0.011) than patients without injury. In a multivariate Cox regression model, it was demonstrated that serum creatinine level (P = 0.019) and heart rate (P = 0.022) were significant risk factors for mortality. Finally, Kaplan-Meier analysis revealed that patients with acute kidney injury suffered lower cumulative survival than without injury (P = 0.016). In summary, the overall mortality rate of charcoal burning suicide population was 3.2%, and acute kidney injury was a powerful predictor of mortality. Further studies are warranted.
authors.affiliation: Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Yu-Chin
authors.initials: YC
authors.lastname: Chen
authors.affiliation: Center for Traditional Chinese Medicine, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
authors.forename: Yi-Chia
authors.initials: YC
authors.lastname: Tseng
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Wen-Hung
authors.initials: WH
authors.lastname: Huang
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Ching-Wei
authors.initials: CW
authors.lastname: Hsu
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Cheng-Hao
authors.initials: CH
authors.lastname: Weng
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Shou-Hsuan
authors.initials: SH
authors.lastname: Liu
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Huang-Yu
authors.initials: HY
authors.lastname: Yang
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Kuan-Hsin
authors.initials: KH
authors.lastname: Chen
authors.affiliation: Department of Dentistry and Craniofacial Orthodontics, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Hui-Ling
authors.initials: HL
authors.lastname: Chen
authors.affiliation: Department of Medical Research, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.
authors.forename: Jen-Fen
authors.initials: JF
authors.lastname: Fu
authors.affiliation: Department of Gastroenterology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.
authors.forename: Wey-Ran
authors.initials: WR
authors.lastname: Lin
authors.affiliation: Department of Nephrology, China Medical University Hospital and College of Medicine, China Medical University, Taichung, Taiwan.
authors.forename: I-Kuan
authors.initials: IK
authors.lastname: Wang
authors.affiliation: Department of Nephrology and Division of Clinical Toxicology, Chang Gung Memorial Hospital and College of Medicine, Chang Gung University, Linkou, Taiwan.|Kidney Research Center, Chang Gung Memorial Hospital, Linkou, Taiwan.|Center for Tissue Engineering, Chang Gung Memorial Hospital, Linkou, Taiwan.
authors.forename: Tzung-Hai
authors.initials: TH
authors.lastname: Yen
mesh_terms: D058186:Acute Kidney Injury / Q000150:complications* / Q000401:mortality; D000328:Adult; D002056:Burns / Q000401:mortality*; D002606:Charcoal; D005260:Female; D006801:Humans; D007902:Length of Stay; D008297:Male; D008875:Middle Aged; D058687:Out-of-Hospital Cardiac Arrest / Q000453:epidemiology / Q000235:genetics; D012131:Respiratory Insufficiency / Q000453:epidemiology / Q000209:etiology; D012189:Retrospective Studies; D012206:Rhabdomyolysis / Q000453:epidemiology / Q000209:etiology; D018570:Risk Assessment; D013406:Suicide, Attempted; D055815:Young Adult
chemical_list: D002606:Charcoal