title: A multidirectional approach to risk assessment in patients with three-vessel coronary artery disease undergoing percutaneous intervention.
abstract: The SYNTAX score (SS) and Clinical SYNTAX score (CSS) have demonstrated utility as risk-stratifying tools following percutaneous coronary intervention (PCI). However, useful determinants for predicting hard clinical events (HCE: death, nonfatal myocardial infarction, and stroke) in the setting of routinely-performed-angiographic follow-up have yet to be elucidated.
  
  
  
  We retrospectively examined the clinical outcomes of 252 three-vessel disease (TVD) patients following PCI. The incidence of HCE at 3 years significantly differed according to CSS (High, 20.2%; Intermediate, 1.2%; and Low, 6.0%; log-rank p<0.001), but not according to SS (High, 14.0%; Intermediate, 5.8%; and Low, 7.3%; log-rank p=0.13). The incidence of repetitive revascularization at 3 years did not differ significantly both among SS (High, 45.2%; Intermediate, 36.5%; and Low, 38.2%; log-rank p=0.22) and CSS (High, 36.9%; Intermediate, 41.7%; and Low, 41.7%; log-rank p=0.88,).
  
  
  
  Prediction of HCE in patients with TVD following PCI was more accurate with CSS than with SS.
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan. Electronic address: t-kashiyama@mail.hts-hsp.com.
authors.forename: Toshikazu
authors.initials: T
authors.lastname: Kashiyama
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Otsuji
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Shin
authors.initials: S
authors.lastname: Takiuchi
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Katsuaki
authors.initials: K
authors.lastname: Asano
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Motoaki
authors.initials: M
authors.lastname: Ibuki
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Katsuyuki
authors.initials: K
authors.lastname: Hasegawa
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Kasumi
authors.initials: K
authors.lastname: Ishibuchi
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Akiko
authors.initials: A
authors.lastname: Fujino
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Rui
authors.initials: R
authors.lastname: Ishii
authors.affiliation: Department of Cardiology, Higashi Takarazuka Satoh Hospital, Hyogo, Japan.
authors.forename: Yorihiko
authors.initials: Y
authors.lastname: Higashino
mesh_terms: D000368:Aged; D003324:Coronary Artery Disease / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D009203:Myocardial Infarction / Q000453:epidemiology*; D062645:Percutaneous Coronary Intervention; D012189:Retrospective Studies; D018570:Risk Assessment; D020521:Stroke / Q000453:epidemiology*
keywords: Clinical SYNTAX score; Hard clinical events; Percutaneous coronary intervention