title: Simulation of parabolic reflectors for ultraviolet phototherapy.
abstract: Ultraviolet (UVR) phototherapy is widely used to treat an array of skin conditions, including psoriasis, eczema and vitiligo. For such interventions, a quantified dose is vital if the treatment is to be both biologically effective and to avoid the detrimental effects of over-dosing. As dose is absorbed at surface level, the orientation of patient site with respect to the UVR lamps modulates effective dose. Previous investigations have modelled this behaviour, and examined the impact of shaped anodized aluminium reflectors typically placed around lamps in phototherapy cabins. These mirrors are effective but tend to yield complex patterns of reflection around the cabin which can result in substantial dose inhomogeneity. There has been some speculation over whether using the reflective property of parabolic mirrors might improve dose delivery or homogeneity through the treatment cabin. In this work, the effects of parabolic mirrors are simulated and compared with standard shaped mirrors. Simulation results strongly suggest that parabolic reflectors reduce total irradiance relative to standard shaped reflectors, and have a negligible impact on dose homogeneity.
authors.affiliation: Cancer Research UK/MRC Oxford Institute for Radiation Oncology, Gray Laboratory, University of Oxford, Old Road Campus Research Building, Off Roosevelt Drive, Oxford OX3 7DQ, UK.
authors.forename: David
authors.initials: D
authors.lastname: Robert Grimes
mesh_terms: D003198:Computer Simulation; D006801:Humans; D008962:Models, Theoretical; D055620:Optical Phenomena; D010789:Phototherapy / Q000295:instrumentation* / Q000379:methods; D011879:Radiotherapy Dosage; D014467:Ultraviolet Therapy / Q000295:instrumentation* / Q000379:methods