title: Managing non-alcoholic fatty liver disease.
abstract: The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing rapidly with the obesity and diabetes mellitus epidemics. It is rapidly becoming the most common cause of liver disease worldwide. NAFLD can progress to serious complications such as cirrhosis, hepatocellular carcinoma and death. Therefore, it is important to recognise this condition so that early intervention can be implemented. Lifestyle modifications and strict control of metabolic risk factors are the mainstay of treatment. As disease progression is slow in the majority of NAFLD patients, most can be managed well by primary care physicians. NAFLD patients with advanced liver fibrosis should be referred to specialist care for further assessment.
authors.affiliation: Singapore General Hospital, Singapore.|Duke-NUS Medical School, Singapore.
authors.forename: Jing Hieng
authors.initials: JH
authors.lastname: Ngu
authors.affiliation: Singapore General Hospital, Singapore.|Duke-NUS Medical School, Singapore.
authors.forename: George Boon Bee
authors.initials: GB
authors.lastname: Goh
authors.affiliation: Frontier Healthcare Group, Singapore.
authors.forename: Zhongxian
authors.initials: Z
authors.lastname: Poh
authors.affiliation: Singapore General Hospital, Singapore.|Duke-NUS Medical School, Singapore.
authors.forename: Roy
authors.initials: R
authors.lastname: Soetikno
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000473:pathology; D004032:Diet; D018450:Disease Progression; D006801:Humans; D008019:Life Style; D008099:Liver / Q000473:pathology; D008103:Liver Cirrhosis / Q000473:pathology; D008113:Liver Neoplasms / Q000473:pathology; D024821:Metabolic Syndrome / Q000150:complications*; D065626:Non-alcoholic Fatty Liver Disease / Q000175:diagnosis / Q000628:therapy*; D009765:Obesity / Q000150:complications; D015995:Prevalence; D012307:Risk Factors; D016896:Treatment Outcome
keywords: fibrosis; metabolic syndrome; non-alcoholic fatty liver disease