title: Sclerosing Angiomatoid Nodular Transformation of the spleen, focal nodular hyperplasia and hemangioma of the liver: A tale of three lesions.
abstract: Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is a benign vascular lesion with peculiar histological features. The pathogenesis of SANT is still largely unknown and variable etiologies have been proposed, including autoimmune, inflammatory, and/or vascular disorders. The present report describes a unique case of splenic SANT, associated with focal nodular hyperplasia and a sclerosing hemangioma of the liver. The clinic-pathological features of such an unusual case are thoroughly illustrated. Its possible pathogenic mechanisms are also briefly addressed.
authors.affiliation: General Pathology & Cytopathology Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy.
authors.forename: Barbara
authors.initials: B
authors.lastname: Cafferata
authors.affiliation: General Pathology & Cytopathology Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy. Electronic address: marcopizzi2002@yahoo.it.
authors.forename: Marco
authors.initials: M
authors.lastname: Pizzi
authors.affiliation: Hepatobiliary Surgery and Liver Transplantation Unit, University of Padova, Padova, Italy.
authors.forename: Francesco
authors.initials: F
authors.lastname: D'Amico
authors.affiliation: General Pathology & Cytopathology Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy.
authors.forename: Claudia
authors.initials: C
authors.lastname: Mescoli
authors.affiliation: General Pathology & Cytopathology Unit, Department of Medicine-DIMED, University of Padova, Padova, Italy.
authors.forename: Rita
authors.initials: R
authors.lastname: Alaggio
mesh_terms: D020518:Focal Nodular Hyperplasia / Q000473:pathology*; D006391:Hemangioma / Q000473:pathology*; D006801:Humans; D008099:Liver / Q000473:pathology*; D008113:Liver Neoplasms / Q000473:pathology*; D008297:Male; D008875:Middle Aged; D012598:Sclerosis / Q000473:pathology; D013154:Spleen / Q000473:pathology*
keywords: Focal nodular hyperplasia; Hemangioma; SANT; Sclerosing Angiomatoid Nodular Transformation; Spleen