title: Sarcopenia and mortality in older people living in a nursing home in Turkey.
abstract: OBJECTIVE
  The aim of the present study was to evaluate the relationship between mortality and sarcopenia defined by the criteria of the European Working Group on Sarcopenia in Older People in older nursing home residents in Turkey.
  
  
  METHODS
  This was an observational prospective study. Nursing home residents who were aged older than 65 years and living in the Seyranbagları Nursing Home and Rehabilitation Center (Ankara, Turkey) were recruited for the study. The main outcome measure was the relationship between sarcopenia and mortality. Diagnosis of sarcopenia was carried out according to the European Working Group on Sarcopenia in Older People criteria. Bioelectrical impedance analysis was used for skeletal muscle mass measurement. Muscle strength and muscle performance were evaluated by handgrip testing and gait speed, respectively. Mortality was assessed at the end of 2 years. The Kaplan-Meier method and Cox regression analysis were used to evaluate the relationship between sarcopenia and all-cause mortality.
  
  
  RESULTS
  The prevalence of sarcopenia and severe sarcopenia were 29% and 25.4%, respectively. A total of 44% (18) of sarcopenic participants died, whereas 15% (15) of participants without sarcopenia died after 2 years of follow up (P < 0.001). After adjusting for confounding factors, sarcopenia was associated with all-cause mortality among older nursing home residents in Turkey (HR 2.38, 95% CI 1.04-5.46; P = 0.039). However, sarcopenia was not significantly related with mortality after adjustment of MNA score (HR 2.04, 95% CI 0.85-4.9; P = 0.1).
  
  
  CONCLUSIONS
  Sarcopenia independently increases all-cause mortality in older nursing home residents in Turkey. Nutritional status plays a role in sarcopenia-related mortality. Geriatr Gerontol Int 2017; 17: 1118-1124.
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Ahmet
authors.initials: A
authors.lastname: Yalcin
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Sevgi
authors.initials: S
authors.lastname: Aras
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Volkan
authors.initials: V
authors.lastname: Atmis
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Ozlem Karaarslan
authors.initials: OK
authors.lastname: Cengiz
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Esat
authors.initials: E
authors.lastname: Cinar
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Teslime
authors.initials: T
authors.lastname: Atli
authors.affiliation: Department of Geriatric Medicine, Ankara University School of Medicine İbn-i, Sina Hospital, Altındağ, Ankara, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Varli
mesh_terms: D000203:Activities of Daily Living; D000368:Aged; D000369:Aged, 80 and over; D002423:Cause of Death; D015331:Cohort Studies; D004185:Disability Evaluation; D005260:Female; D015577:Geriatric Assessment / Q000379:methods; D006707:Homes for the Aged; D006801:Humans; D053208:Kaplan-Meier Estimate; D008137:Longitudinal Studies; D008297:Male; D053580:Muscle Strength / Q000502:physiology; D018482:Muscle, Skeletal / Q000503:physiopathology*; D009735:Nursing Homes; D016016:Proportional Hazards Models; D011446:Prospective Studies; D055948:Sarcopenia / Q000175:diagnosis* / Q000401:mortality*; D012720:Severity of Illness Index; D018709:Statistics, Nonparametric; D016019:Survival Analysis; D014421:Turkey
keywords: European Working Group on Sarcopenia in Older People; mortality; nursing home; sarcopenia