title: Ultrasonographic measurements of the inferior vena cava variation as a predictor of fluid responsiveness in patients undergoing anesthesia for surgery.
abstract: Both hypovolemia and hypervolemia are connected with increased morbidity and mortality in the treatment and prognosis of patients. An accurate assessment of volume state allows the optimization of organ perfusion and oxygen supply. Recently, ultrasonography has been used to detect hypovolemia in critically ill patients and perioperative patients. The objective of our study was to assess the correlation between inferior vena cava (IVC) variation obtained with ultrasound and stroke volume variation (SVV) measured by the Vigileo/FloTrac monitor, as fluid responsiveness indicators, in patients undergoing anesthesia for surgery.
  
  
  
  Forty patients (American Society of Anesthesiologists grades I and II) scheduled for elective gastrointestinal surgery were enrolled in our study. After anesthesia induction, 6% hydroxyethyl starch solution was administered to patients as an intravenous (IV) fluid. The IVC diameters were measured with ultrasonography. SVV and stroke volume index (SVI) were obtained from the Vigileo monitor. All data were collected both before and after fluid challenge.
  
  
  
  Forty patients underwent IVC sonographic measurements and SVV calculation. After fluid challenge, mean arterial pressure, central venous pressure, SVI, and IVC diameters increased significantly, whereas SVV decreased markedly. The correlation coefficient between the increase in SVI and the baseline of IVC variation after an IV fluid was 0.710, and receiver operating characteristic (ROC) curve was 0.85. The correlation coefficient between the increase in SVI and the baseline of SVV was 0.803 with an ROC curve of 0.93. Central venous pressure had no significant correlation with SVI.
  
  
  
  Our data show that IVC variation and SVV proved to be reliable predictors of fluid responsiveness in patients undergoing anesthesia for surgery with mechanical ventilation.
authors.affiliation: Department of Anesthesiology, The First People's Hospital of Lianyungang City, Lianyungang, China.
authors.forename: Xiaobao
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Department of Anesthesiology, The First People's Hospital of Lianyungang City, Lianyungang, China.
authors.forename: Jiying
authors.initials: J
authors.lastname: Feng
authors.affiliation: Department of Anesthesiology, The First People's Hospital of Lianyungang City, Lianyungang, China.
authors.forename: Pin
authors.initials: P
authors.lastname: Zhu
authors.affiliation: Department of Anesthesiology, The First People's Hospital of Lianyungang City, Lianyungang, China.
authors.forename: Hengfei
authors.initials: H
authors.lastname: Luan
authors.affiliation: Department of Anesthesiology, The First People's Hospital of Lianyungang City, Lianyungang, China. Electronic address: 18961325621@163.com.
authors.forename: Yong
authors.initials: Y
authors.lastname: Wu
authors.affiliation: Department of Anesthesiology, The First People's Hospital of Lianyungang City, Lianyungang, China. Electronic address: lygzhaozb@126.com.
authors.forename: Zhibin
authors.initials: Z
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D000758:Anesthesia; D013505:Digestive System Surgical Procedures; D017558:Elective Surgical Procedures; D005260:Female; D006801:Humans; D020896:Hypovolemia / Q000000981:diagnostic imaging* / Q000503:physiopathology; D008297:Male; D008875:Middle Aged; D012121:Respiration, Artificial; D012680:Sensitivity and Specificity; D013318:Stroke Volume; D014463:Ultrasonography; D014682:Vena Cava, Inferior / Q000000981:diagnostic imaging*
keywords: Central venous pressure; Fluid responsiveness; Gastrointestinal surgery; Inferior vena cava; Stroke volume variation