title: [Prediction of the efficiency of endoscopic lung volume reduction by valves in severe emphysema].
abstract: BACKGROUND
  In severe emphysema, endoscopic lung volume reduction with valves is an alternative to surgery with less morbidity and mortality. In 2015, selection of patients who will respond to this technique is based on emphysema heterogeneity, a complete fissure visible on the CT-scan and absence of collateral ventilation between lobes. Our case report highlights that individualized prediction is possible.
  
  
  METHODS
  A 58-year-old woman had severe, disabling pulmonary emphysema. A high resolution thoracic computed tomography scan showed that the emphysema was heterogeneous, predominantly in the upper lobes, integrity of the left greater fissure and no collateral ventilation with the left lower lobe. A valve was inserted in the left upper lobe bronchus. At one year, clinical and functional benefits were significant with complete atelectasis of the treated lobe.
  
  
  CONCLUSIONS
  The success of endoscopic lung volume reduction with a valve can be predicted, an example of personalized medicine.
authors.affiliation: Clinique universitaire de pneumologie, pôle thorax et vaisseaux, CHU de Grenoble, CS10217, 38043 Grenoble cedex 9, France; Université Grenoble Alpes, 38000 Grenoble, France. Electronic address: vbocquillon@chu-grenoble.fr.
authors.forename: V
authors.initials: V
authors.lastname: Bocquillon
authors.affiliation: Clinique universitaire de pneumologie, pôle thorax et vaisseaux, CHU de Grenoble, CS10217, 38043 Grenoble cedex 9, France; Université Grenoble Alpes, 38000 Grenoble, France.
authors.forename: A
authors.initials: A
authors.lastname: Briault
authors.affiliation: Université Grenoble Alpes, 38000 Grenoble, France; Clinique universitaire de radiologie, CHU de Grenoble, 38000 Grenoble, France.
authors.forename: E
authors.initials: E
authors.lastname: Reymond
authors.affiliation: Clinique universitaire de pneumologie, pôle thorax et vaisseaux, CHU de Grenoble, CS10217, 38043 Grenoble cedex 9, France; Université Grenoble Alpes, 38000 Grenoble, France.
authors.forename: F
authors.initials: F
authors.lastname: Arbib
authors.affiliation: Université Grenoble Alpes, 38000 Grenoble, France; Clinique universitaire de radiologie, CHU de Grenoble, 38000 Grenoble, France.
authors.forename: A
authors.initials: A
authors.lastname: Jankowski
authors.affiliation: Université Grenoble Alpes, 38000 Grenoble, France; Clinique universitaire de radiologie, CHU de Grenoble, 38000 Grenoble, France.
authors.forename: G
authors.initials: G
authors.lastname: Ferretti
authors.affiliation: Clinique universitaire de pneumologie, pôle thorax et vaisseaux, CHU de Grenoble, CS10217, 38043 Grenoble cedex 9, France; Université Grenoble Alpes, 38000 Grenoble, France.
authors.forename: C
authors.initials: C
authors.lastname: Pison
mesh_terms: D001999:Bronchoscopy / Q000379:methods; D005260:Female; D006801:Humans; D008168:Lung / Q000473:pathology / Q000601:surgery*; D008875:Middle Aged; D009929:Organ Size; D011013:Pneumonectomy / Q000379:methods*; D011379:Prognosis; D011656:Pulmonary Emphysema / Q000175:diagnosis* / Q000473:pathology / Q000601:surgery*; D012720:Severity of Illness Index; D016896:Treatment Outcome
keywords: Bronchopneumopathie chronique obstructive; COPD; Emphysema; Emphysème; Endobronchial valve; Lung volume reduction; Réduction de volume; Thoracic computed tomography; Tomodensitométrie thoracique; Valve endobronchique