title: Return of the Great Pox.
abstract: Syphilis is on the increase globally. While recognized more frequently in patients with, HIV/AIDS, it is not unusual among immune competent individuals sometimes presenting with unusual manifestations and/or behaviour. This paper reviews the history and clinical features of syphilis and draws attention to the oral manifestations. CPD/Clinical Relevance: Syphilis should be in the differential diagnosis of oral ulcers or unusual oral lesions.
authors.forename: Crispian
authors.initials: C
authors.lastname: Scully
authors.forename: Jane F
authors.initials: JF
authors.lastname: Setterfield
mesh_terms: D006801:Humans; D009059:Mouth Diseases / Q000382:microbiology; D013587:Syphilis / Q000150:complications / Q000175:diagnosis / Q000628:therapy