title: Disseminated mucormycosis (DM) after pneumonectomy: a case report.
abstract: Mucormycosis is a kind of rare opportunistic fungal disease and the incidence of which has gradually increased. Disseminated mucormycosis (DM) is a life-threatening infection that mostly occurs in immunocompromised patients. The lung and brain are usually involved in disseminated mucormycosis, and other sites are scare. We report the first case of disseminated mucormycosis whose infection sites included lung, skin, liver, vertebra, and spinal cord that ensued after a right lung pneumonectomy in an immunocompetent patient.
  
  
  
  A 20-year-old female underwent a right lung pneumonectomy for "lung cancer" presented with an intermittent fever for two years. A computed tomography (CT) scan showed an enclosed outstanding mass in the right chest wall. The patient also suffered from lower limb numbness and weakness, difficulty walking, and dysuria. Medical examination showed superficial feeling of the abdominal wall was decreased from the T7 and T8 level; muscle strength for both lower limbs was decreased; muscle tension of both lower limbs was also diminished. A biopsy through the right chest wall mass and thoracic mass by fistula of chest wall showed broad nonseptate hyphae with right-angle branching, consistent with mucormycosis. With titration of amphotericin B and its lipid complex, the patient recovered.
  
  
  
  Our case showed an unusual clinical presentation of disseminated mucormycosisin an immunocompetent patient.
authors.affiliation: Department of Infectious Diseases, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.
authors.forename: Qian
authors.initials: Q
authors.lastname: Wang
authors.affiliation: Department of Infectious Diseases, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China.|Department of Infection Management, The First Affiliated Hospital with Nanjing Medical University, Nanjing, 210029, China.
authors.forename: Bo
authors.initials: B
authors.lastname: Liu
authors.affiliation: Department of Infectious Diseases, The First Affiliated Hospital with Nanjing Medical University, 300 Guangzhou Road, Nanjing, 210029, Jiangsu, China. yyd33@sina.com.
authors.forename: Youde
authors.initials: Y
authors.lastname: Yan
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D001842:Bone and Bones / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D005260:Female; D006801:Humans; D007121:Immunocompetence; D008099:Liver / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D008168:Lung / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology / Q000601:surgery; D009091:Mucormycosis / Q000175:diagnosis* / Q000382:microbiology; D009894:Opportunistic Infections / Q000175:diagnosis* / Q000188:drug therapy; D011013:Pneumonectomy / Q000009:adverse effects*; D012867:Skin / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D013116:Spinal Cord / Q000000981:diagnostic imaging / Q000382:microbiology / Q000473:pathology; D014057:Tomography, X-Ray Computed; D055815:Young Adult
chemical_list: D000935:Antifungal Agents; D000666:Amphotericin B
keywords: Case report; Disseminated mucormycosis; Immunocompetent; Pneumonectomy