title: Transapical Mitral Valve Replacement for Mixed Native Mitral Stenosis and Regurgitation.
abstract: A 71-year-old man presented with New York Heart Association (NYHA) class IV heart failure. He had undergone transapical mitral valve replacement for mixed mitral stenosis and mitral regurgitation. At the 1 month follow-up, the patient reported symptom resolution. An echocardiogram revealed a low gradient and no regurgitation. Our case shows that with careful multidisciplinary evaluation, preoperative planning, and patient selection, percutaneous mitral intervention can become an alternative therapy for high-risk patients who cannot undergo conventional surgical therapy.
authors.affiliation: Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington. Electronic address: ebedzra@uw.edu.
authors.forename: Edo
authors.initials: E
authors.lastname: Bedzra
authors.affiliation: Division of Cardiology, University of Washington Medical Center, Seattle, Washington.
authors.forename: Creighton W
authors.initials: CW
authors.lastname: Don
authors.affiliation: Division of Cardiology, University of Washington Medical Center, Seattle, Washington.
authors.forename: Mark
authors.initials: M
authors.lastname: Reisman
authors.affiliation: Division of Cardiothoracic Surgery, University of Washington Medical Center, Seattle, Washington.
authors.forename: Gabriel S
authors.initials: GS
authors.lastname: Aldea
mesh_terms: D000368:Aged; D017130:Angioplasty / Q000379:methods*; D001705:Bioprosthesis; D006328:Cardiac Catheterization / Q000379:methods; D002315:Cardiopulmonary Bypass / Q000379:methods; D015150:Echocardiography, Doppler; D005500:Follow-Up Studies; D006333:Heart Failure / Q000175:diagnosis / Q000209:etiology; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008944:Mitral Valve Insufficiency / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D008946:Mitral Valve Stenosis / Q000150:complications / Q000000981:diagnostic imaging / Q000601:surgery*; D011474:Prosthesis Design; D018570:Risk Assessment; D012720:Severity of Illness Index; D016896:Treatment Outcome