title: Prevalence of Atopic Dermatitis in Chinese Children aged 1-7 ys.
abstract: Prevalence of atopic dermatitis (AD) is increasing worldwide. Up to date, there has been no face-to-face nation-wide study in China. We aim to explore the prevalence of clinical diagnosed AD in children aged 1-7 ys in China. Twelve metropolises were chosen from different areas of China. In each region, we selected 4-10 kindergartens and 2-5 vaccination clinics randomly. A complete history-taking and skin examination were performed by dermatologists. The definite diagnosis of AD and the severity were determined by two or three dermatologists. All criteria concerned in UK diagnosis criteria, characteristic presentation of AD and atypical manifestations were recorded in detail. A total of 13998 children from 84 kindergartens and 40 vaccination clinics were included. The prevalence of AD was 12.94% by clinical diagnosis of dermatologists overall, with 74.6% of mild AD. Comparatively, prevalence of AD based on UK diagnostic criteria was 4.76%. This is the first face-to-face nation-wide study in Chinese children aged 1-7 ys, revealing that the prevalence of AD in children is closer to that of wealthier nations.
authors.affiliation: Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Yifeng
authors.initials: Y
authors.lastname: Guo
authors.affiliation: Department of Dermatology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.affiliation: Department of Dermatology, Hunan Children's Hospital, Changsha, Hunan, China.
authors.forename: Jianping
authors.initials: J
authors.lastname: Tang
authors.affiliation: Department of Dermatology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China.
authors.forename: Xiuping
authors.initials: X
authors.lastname: Han
authors.affiliation: Department of Dermatology, Hubei Maternity and Child Health Hospital, Wuhan, Hubei, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Zou
authors.affiliation: Department of Community Health and Family Medicine, School of Public Health, Shanghai Jiaotong University, Shanghai, China.
authors.forename: Gang
authors.initials: G
authors.lastname: Xu
authors.affiliation: Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
authors.forename: Zigang
authors.initials: Z
authors.lastname: Xu
authors.affiliation: Department of Dermatology, Dalian Children's Hospital, Dalian, Liaoning, China.
authors.forename: Fenglei
authors.initials: F
authors.lastname: Wei
authors.affiliation: Department of Dermatology, Shanxi Children's Hospital, Taiyuan, Shanxi, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: Liu
authors.affiliation: Department of Dermatology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.affiliation: Institute of Dermatology and Department of Dermatology, No.1 Hospital, Anhui Medical University, Hefei, Anhui, China.
authors.forename: Fengli
authors.initials: F
authors.lastname: Xiao
authors.affiliation: Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College, Nanjing, Jiangsu, China.
authors.forename: Wenkai
authors.initials: W
authors.lastname: Zong
authors.affiliation: Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
authors.forename: Chunping
authors.initials: C
authors.lastname: Shen
authors.affiliation: Department of Dermatology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
authors.forename: Jianhong
authors.initials: J
authors.lastname: Li
authors.affiliation: Department of Dermatology, Shenzhen Children's Hospital, Shenzhen, Guangdong, China.
authors.forename: Jianzhong
authors.initials: J
authors.lastname: Liu
authors.affiliation: Department of Dermatology, Hunan Children's Hospital, Changsha, Hunan, China.
authors.forename: Yongqi
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Department of Dermatology, Hunan Children's Hospital, Changsha, Hunan, China.
authors.forename: Jing
authors.initials: J
authors.lastname: Chang
authors.affiliation: Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College, Nanjing, Jiangsu, China.
authors.forename: Nan
authors.initials: N
authors.lastname: Sheng
authors.affiliation: Department of Dermatology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Dong
authors.affiliation: Department of Dermatology, Shengjing Hospital, China Medical University, Shenyang, Liaoning, China.
authors.forename: Duo
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Department of Dermatology, Hubei Maternity and Child Health Hospital, Wuhan, Hubei, China.
authors.forename: Xing
authors.initials: X
authors.lastname: Dai
authors.affiliation: Department of Dermatology, Hubei Maternity and Child Health Hospital, Wuhan, Hubei, China.
authors.forename: Jinjie
authors.initials: J
authors.lastname: Zhou
authors.affiliation: Department of Dermatology, Hubei Maternity and Child Health Hospital, Wuhan, Hubei, China.
authors.forename: Chi
authors.initials: C
authors.lastname: Meng
authors.affiliation: Department of Dermatology, Dalian Children's Hospital, Dalian, Liaoning, China.
authors.forename: Hongxi
authors.initials: H
authors.lastname: Niu
authors.affiliation: Department of Dermatology, Dalian Children's Hospital, Dalian, Liaoning, China.
authors.forename: Xuemei
authors.initials: X
authors.lastname: Shi
authors.affiliation: Department of Dermatology, Shanxi Children's Hospital, Taiyuan, Shanxi, China.
authors.forename: Xinglian
authors.initials: X
authors.lastname: Zhang
authors.affiliation: Pediatric Dermatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Juan
authors.initials: J
authors.lastname: Xiang
authors.affiliation: Department of Dermatology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.
authors.forename: Haitao
authors.initials: H
authors.lastname: Xu
authors.affiliation: Department of Dermatology, Chengdu Women's and Children's Central Hospital, Chengdu, Sichuan, China.
authors.forename: Qin
authors.initials: Q
authors.lastname: Ran
authors.affiliation: Institute of Dermatology and Department of Dermatology, No.1 Hospital, Anhui Medical University, Hefei, Anhui, China.
authors.forename: Yi
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Ming
authors.initials: M
authors.lastname: Li
authors.affiliation: Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Hui
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Ruhong
authors.initials: R
authors.lastname: Cheng
authors.affiliation: Department of Dermatology, The First Hospital of China Medical University, Shenyang, Liaoning, China.
authors.forename: Xinghua
authors.initials: X
authors.lastname: Gao
authors.affiliation: Pediatric Dermatology, Children's Hospital of Chongqing Medical University, Chongqing, China.
authors.forename: Hua
authors.initials: H
authors.lastname: Wang
authors.affiliation: Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College, Nanjing, Jiangsu, China.
authors.forename: Heng
authors.initials: H
authors.lastname: Gu
authors.affiliation: Department of Dermatology, Beijing Children's Hospital, Capital Medical University, Beijing, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Ma
authors.affiliation: Department of Dermatology, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
authors.forename: Zhirong
authors.initials: Z
authors.lastname: Yao
mesh_terms: D044466:Asian People; D002648:Child; D002675:Child, Preschool; D002681:China / Q000453:epidemiology; D003876:Dermatitis, Atopic / Q000175:diagnosis* / Q000453:epidemiology* / Q000208:ethnology; D005260:Female; D005843:Geography; D006801:Humans; D007223:Infant; D008297:Male; D015995:Prevalence; D012307:Risk Factors; D012867:Skin / Q000473:pathology*; D011795:Surveys and Questionnaires