title: Ruthenium(II)-Catalyzed Traceless C-H Functionalization Using an N-N Bond as an Internal Oxidant.
abstract: A previously elusive Ru(II) -catalyzed N-N bond-based traceless C-H functionalization strategy is reported. An N-amino (i.e., hydrazine) group is used for the directed C-H functionalization with either an alkyne or an alkene, affording an indole derivative or olefination product. The synthesis features a broad substrate scope, superior atom and step economy, as well as mild reaction conditions.
authors.affiliation: Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, 210093, P. R. China.
authors.forename: Shuguang
authors.initials: S
authors.lastname: Zhou
authors.affiliation: Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, 210093, P. R. China.
authors.forename: Jinhu
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, 210093, P. R. China.
authors.forename: Pei
authors.initials: P
authors.lastname: Chen
authors.affiliation: Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, 210093, P. R. China.
authors.forename: Kehao
authors.initials: K
authors.lastname: Chen
authors.affiliation: Department of Polymer Science and Engineering, School of Chemistry and Chemical Engineering, State Key Laboratory of Coordination Chemistry, Nanjing National Laboratory of Microstructures, Nanjing University, Nanjing, 210093, P. R. China. jinz@nju.edu.cn.
authors.forename: Jin
authors.initials: J
authors.lastname: Zhu
keywords: C−H functionalization; N−N bond cleavage; indoles; olefination; ruthenium