title: Pulmonary Aspergillosis in a Previously Healthy 13-Year-Old Boy.
abstract: Chronic granulomatous disease (CGD) is a rare, polygenic primary immunodeficiency. In this case report, we describe a previously healthy 13-year-old boy who presented with multifocal pulmonary aspergillosis and was subsequently diagnosed with an autosomal recessive form of chronic granulomatous disease. CGD has a variable natural history and age of presentation and should be considered when investigating a patient with recurrent or severe infections with catalase-positive organisms.
authors.affiliation: Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
authors.forename: Jonathan H
authors.initials: JH
authors.lastname: Rayment
authors.affiliation: Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada.
authors.forename: Indra
authors.initials: I
authors.lastname: Narang
mesh_terms: D000293:Adolescent; D001232:Aspergillus fumigatus / Q000302:isolation & purification; D002648:Child; D006801:Humans; D008297:Male; D055732:Pulmonary Aspergillosis / Q000000981:diagnostic imaging* / Q000382:microbiology; D013902:Radiography, Thoracic