title: Driving Apart and Segregating Genomes in Archaea.
abstract: Genome segregation is a fundamental biological process in organisms from all domains of life. How this stage of the cell cycle unfolds in Eukarya has been clearly defined and considerable progress has been made to unravel chromosome partition in Bacteria. The picture is still elusive in Archaea. The lineages of this domain exhibit different cell-cycle lifestyles and wide-ranging chromosome copy numbers, fluctuating from 1 up to 55. This plurality of patterns suggests that a variety of mechanisms might underpin disentangling and delivery of DNA molecules to daughter cells. Here I describe recent developments in archaeal genome maintenance, including investigations of novel genome segregation machines that point to unforeseen bacterial and eukaryotic connections.
authors.affiliation: Department of Biology, University of York, York YO10 5DD, UK. Electronic address: daniela.barilla@york.ac.uk.
authors.forename: Daniela
authors.initials: D
authors.lastname: Barillà
mesh_terms: D001105:Archaea / Q000235:genetics*; D019843:Archaeal Proteins / Q000235:genetics*; D001419:Bacteria / Q000235:genetics; D002453:Cell Cycle / Q000235:genetics; D017124:Conserved Sequence; D004247:DNA / Q000235:genetics / Q000378:metabolism; D004261:DNA Replication; D005057:Eukaryotic Cells; D020745:Genome, Archaeal; D010957:Plasmids / Q000235:genetics
chemical_list: D019843:Archaeal Proteins; D004247:DNA
keywords: Archaea.; chromosome; genome segregation; plasmid