title: Effect of cordocentesis on fetal myocardial performance.
abstract: OBJECTIVE
  To compare fetal Tei index before, immediately after and 30 min after cordocentesis for prenatal diagnosis.
  
  
  METHODS
  Pregnant women undergoing prenatal diagnostic cordocentesis in the early mid-trimester underwent measurement of the fetal Tei index of both right and left ventricles just before cordocentesis, immediately after and at 30 min after the procedure.
  
  
  RESULTS
  A total of 143 singleton women underwent cordocentesis at a median gestational age of 19 weeks (range 16-23). The most common indication was fetal risk of beta-thalassemia/hemoglobin E disease (42%, 60 cases). Immediately after cordocentesis, fetal Tei index and all its components at both ventricles were significantly altered when compared with the baseline values (p < 0.001). At 30 min after cordocentesis, components of the Tei index had significantly improved but 5/6 had not completely recovered. No serious procedure-related short-term complications were observed in the study.
  
  
  CONCLUSIONS
  Cordocentesis has a negative impact on fetal hemodynamics as indicated by worsening of the Tei index. Although the adverse effect seems to be temporary, the recovery time may be longer than 30 min. © 2016 John Wiley & Sons, Ltd.
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand. ksrisupundit@yahoo.com.
authors.forename: Kasemsri
authors.initials: K
authors.lastname: Srisupundit
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: Fuanglada
authors.initials: F
authors.lastname: Tongprasert
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: Suchaya
authors.initials: S
authors.lastname: Luewan
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: Kuntharee
authors.initials: K
authors.lastname: Traisrisilp
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: Phudit
authors.initials: P
authors.lastname: Jatavan
authors.affiliation: Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand.
authors.forename: Theera
authors.initials: T
authors.lastname: Tongsong
mesh_terms: D017218:Cordocentesis / Q000009:adverse effects*; D005260:Female; D005318:Fetal Heart / Q000502:physiology*; D006801:Humans; D011247:Pregnancy