title: Capturing Darwin's dream.
abstract: Evolutionary biologists from Darwin forward have dreamed of having data that would elucidate our understanding of evolutionary history and the diversity of life. Sequence capture is a relatively old DNA technology, but its use is growing rapidly due to advances in (i) massively parallel DNA sequencing approaches and instruments, (ii) massively parallel bait construction, (iii) methods to identify target regions and (iv) sample preparation. We give a little historical context to these developments, summarize some of the important advances reported in this special issue and point to further advances that can be made to help fulfill Darwin's dream.
authors.affiliation: Department of Environmental Health Science, University of Georgia, Environmental Health Science Bldg., Athens, GA, 30602, USA.
authors.forename: Travis C
authors.initials: TC
authors.lastname: Glenn
authors.affiliation: Department of Biological Sciences and Museum of Natural Science, Louisiana State University, Baton Rouge, LA, 70803, USA.
authors.forename: Brant C
authors.initials: BC
authors.lastname: Faircloth
mesh_terms: D005075:Biological Evolution; D001695:Biology / Q000266:history* / Q000295:instrumentation / Q000379:methods*; D004247:DNA / Q000737:chemistry / Q000235:genetics / Q000302:isolation & purification; D014644:Genetic Variation; D060005:Genotyping Techniques / Q000295:instrumentation / Q000379:methods* / Q000639:trends; D059014:High-Throughput Nucleotide Sequencing / Q000295:instrumentation / Q000379:methods; D049673:History, 20th Century; D049674:History, 21st Century; D009693:Nucleic Acid Hybridization / Q000379:methods; D013048:Specimen Handling / Q000379:methods
chemical_list: D004247:DNA
keywords: Illumina; biotinylated baits; massively parallel sequencing; next-generation sequencing; sequence capture; target enrichment