title: Acute Myeloid Leukemia in Children: Experience from Tertiary Cancer Centre in India.
abstract: There is paucity of data in pediatric Acute Myeloid Leukemia (AML) from developing countries. We analyzed the outcomes of 65 consecutive patients with pediatric AML treated at our centre from January-2008 to May-2013. The median event free survival (EFS) and overall survival (OS) were 12.6 and 14.6 months respectively. Patients with good-risk cytogenetics had a better EFS (p = 0.004) and OS (p = 0.01). Overall, these results are not comparable to that observed in other centres globally and leaves scope for further improvement. This includes implementing allogeneic bone marrow transplantation as a treatment for all children with high-risk AML.
authors.affiliation: Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: Venkatraman
authors.initials: V
authors.lastname: Radhakrishnan
authors.affiliation: Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: Cherian
authors.initials: C
authors.lastname: Thampy
authors.affiliation: Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: Prasanth
authors.initials: P
authors.lastname: Ganesan
authors.affiliation: Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: Rejiv
authors.initials: R
authors.lastname: Rajendranath
authors.affiliation: Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: Trivadi S
authors.initials: TS
authors.lastname: Ganesan
authors.affiliation: Department of Pathology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: K R
authors.initials: KR
authors.lastname: Rajalekshmy
authors.affiliation: Departments of Medical Oncology, Cancer Institute (WIA), Adyar, Chennai India.
authors.forename: Tenali Gnana
authors.initials: TG
authors.lastname: Sagar
keywords: Acute Myeloid Leukemia; Chemotherapy; Survival