title: [Chronic cough, pleuritic chest pain, and night sweats in a 45‑year-old female smoker].
abstract: A 45-year-old woman presented with chronic cough, pleuritic chest pain, and night sweat. High-resolution computed tomography revealed multiple bilateral nodular lesions in a centrilobular distribution, primarily located in the upper and mid lung zones with relative sparing of the lung bases. No lymphadenopathy or pleural effusions were detected. Histological analysis confirmed the suspected diagnosis of pulmonary Langerhans cell histiocytosis. After smoking cessation the patient recovered completely.
authors.affiliation: Medizinische Klinik mit Schwerpunkt Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland. alexander.gross@charite.de.
authors.forename: A
authors.initials: A
authors.lastname: Gross
authors.affiliation: Medizinische Klinik für Kardiologie und Pulmologie, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Hortig
authors.affiliation: Institut für Pathologie, Charité - Universitätsmedizin Berlin, Campus Mitte, Berlin, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Darb-Esfahani
authors.affiliation: Medizinische Klinik mit Schwerpunkt Gastroenterologie, Infektiologie und Rheumatologie, Charité - Universitätsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Schneider
mesh_terms: D002637:Chest Pain / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control; D002908:Chronic Disease; D003371:Cough / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D005260:Female; D006646:Histiocytosis, Langerhans-Cell / Q000150:complications / Q000175:diagnosis* / Q000517:prevention & control*; D006801:Humans; D006945:Hyperhidrosis / Q000175:diagnosis / Q000209:etiology* / Q000517:prevention & control*; D008875:Middle Aged; D010998:Pleurisy / Q000175:diagnosis / Q000209:etiology / Q000517:prevention & control*; D012907:Smoking / Q000009:adverse effects*; D016540:Smoking Cessation; D016896:Treatment Outcome
keywords: Histiocytosis, Langerhans-cell, pulmonary; Lung diseases, interstitial; Smoking; Tomography, X‑ray computed, high-resolution; Tuberculosis, pulmonary