title: Noninvasive brain stimulation enhances sustained muscle contractions by reducing neuromuscular fatigue: implications for rehabilitation.
abstract: Neuromuscular fatigue is due, in part, to central processes that involve failure of the nervous system to drive muscles maximally during exercise. A recent study by Abdelmoula, Baudry, and Duchateau (Neuroscience322: 94-103, 2016) showed that noninvasive brain stimulation can mitigate neuromuscular fatigue, however, does not rely on enhanced corticospinal excitability of the primary motor cortex. These findings are of high clinical importance because rehabilitative therapies are necessary to mitigate neuromuscular fatigue for patients with central nervous system disorders.
authors.affiliation: Human Performance and Engineering Research, Kessler Foundation, West Orange, New Jersey dcunningham@kesslerfoundation.org.
authors.forename: David A
authors.initials: DA
authors.lastname: Cunningham
mesh_terms: D006801:Humans; D009044:Motor Cortex / Q000502:physiology*; D009119:Muscle Contraction / Q000502:physiology*; D018763:Muscle Fatigue / Q000502:physiology*; D018482:Muscle, Skeletal / Q000502:physiology; D050781:Transcranial Magnetic Stimulation
keywords: central activation failure; central fatigue; neuromuscular fatigue; noninvasive brain stimulation