title: Effects of whole-body vibration training in patients with multiple sclerosis: A systematic review.
abstract: BACKGROUND
  Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system. MS is characterised by nerve demyelination that can alter nerve transmission and lead to such symptoms as fatigue, muscle weakness, and impaired motor function. There are 47 000 people with MS in Spain. Vibration training can be an effective and complementary alternative to traditional exercise to treat patients with MS. The aim of this study was to analyse the effectiveness of vibration training programmes in patients with MS.
  
  
  METHODS
  We searched 5 electronic databases (PubMed, SPORTDiscus, SciELO, Lilacs, IBECS, and ISI Web of Knowledge) in August 2015. By using a set of keywords, we found studies linking vibration training and MS and included randomised controlled trials that applied vibration training to patients with MS. Our search yielded 71 studies. Only 9 of them were included after removing duplicate studies and those which were not relevant according to our selection criteria. These studies obtained different outcomes.
  
  
  CONCLUSIONS
  Some studies found improvements in muscle strength, functional capacity, coordination, resistance, balance, and some areas of MSSS-88. However, we identified limitations in some of these studies and there are still few publications on vibration training and multiple sclerosis to ensure training effectiveness.
authors.affiliation: Cátedra de Fisiología del Deporte, Universidad Católica de Murcia, Murcia, España.
authors.forename: I
authors.initials: I
authors.lastname: Castillo-Bueno
authors.affiliation: Centro de Investigación en Alto Rendimiento (CIARD), Universidad Católica de Murcia, Murcia, España; Facultad de Deporte, Universidad Católica de Murcia, Murcia, España.
authors.forename: D J
authors.initials: DJ
authors.lastname: Ramos-Campo
authors.affiliation: Centro de Investigación en Alto Rendimiento (CIARD), Universidad Católica de Murcia, Murcia, España; Facultad de Deporte, Universidad Católica de Murcia, Murcia, España. Electronic address: jararias@ucam.edu.
authors.forename: J A
authors.initials: JA
authors.lastname: Rubio-Arias
mesh_terms: D006801:Humans; D009103:Multiple Sclerosis / Q000628:therapy*; D026741:Physical Therapy Modalities; D016032:Randomized Controlled Trials as Topic; D014732:Vibration / Q000627:therapeutic use*
keywords: Balance; Equilibrio; Fatiga; Fatigue; Fuerza; Mielina; Myelin; Resistance; Resistencia; Strength; Vibración; Vibration