title: Congenital Glioblastoma: Lessons Learned from a Rare Case with Unusual Presentation.
abstract: Congenital glioblastomas are uncommon tumors of infancy with unique molecular features and usually better prognosis compared to their pediatric and adult counterparts. A 15-day old newborn harboring a congenital glioblastoma undiagnosed at pregnancy presented to our emergencies with rapid neurological deterioration. Radiological investigations revealed an 8 by 9 cm space occupying and enhancing lesion in the left temporoparietooccipital region with intratumoral hemorrhage. The patient was immediately transferred to the operative theater and was operated in a poor condition. Unfortunately he showed no improvement post-operatively and died within two days in the intensive care unit. As such presentation is unique; we present the case and review the relevant literature concerning the potential pitfalls in diagnosis, management strategies and improvements in outcome.
authors.affiliation: Fattouma Bourguiba University Hospital, Department of Neurosurgery, Monastir, Tunisia.
authors.forename: Atef Ben
authors.initials: AB
authors.lastname: Nsir
authors.forename: Mehdi
authors.initials: M
authors.lastname: Darmoul
authors.forename: Rym
authors.initials: R
authors.lastname: Hadhri
authors.forename: Nejib
authors.initials: N
authors.lastname: Hattab
mesh_terms: D000328:Adult; D001932:Brain Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery*; D003937:Diagnosis, Differential; D017809:Fatal Outcome; D005260:Female; D005909:Glioblastoma / Q000000981:diagnostic imaging* / Q000601:surgery*; D006801:Humans; D007231:Infant, Newborn; D008297:Male; D011247:Pregnancy; D011379:Prognosis