title: Successful treatment of postoperative multidrug-resistant Acinetobacter baumannii meningitis by tigecycline.
abstract: Tigecycline is a broad-spectrum antibiotic with activity against multidrug-resistant (MDR) bacteria. It has limited indications. Studies are necessary to elaborate new guidelines. Here we report a case of postoperative MDR Acinetobacter baumannii meningitis treated by tigecycline combined with colimycin for 21 days. The treatment was well tolerated with a favourable outcome. In conclusion, tigecycline was shown to be effective in a case of MDR A. baumannii meningitis.
authors.affiliation: Department of Infectious Diseases, Fattouma Bourguiba Hospital, Farhat Hached Street 5000, Monastir, Tunisia. Electronic address: kooli.ikbel@gmail.com.
authors.forename: Ikbel
authors.initials: I
authors.lastname: Kooli
authors.affiliation: Department of Infectious Diseases, Fattouma Bourguiba Hospital, Farhat Hached Street 5000, Monastir, Tunisia.
authors.forename: Hajer Ben
authors.initials: HB
authors.lastname: Brahim
authors.affiliation: Department of Neurosurgery, Fattouma Bourguiba Hospital, Monastir, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Kilani
authors.affiliation: Department of Neurosurgery, Fattouma Bourguiba Hospital, Monastir, Tunisia.
authors.forename: Chokri
authors.initials: C
authors.lastname: Gannouni
authors.affiliation: Department of Infectious Diseases, Fattouma Bourguiba Hospital, Farhat Hached Street 5000, Monastir, Tunisia.
authors.forename: Abir
authors.initials: A
authors.lastname: Aouam
authors.affiliation: Department of Infectious Diseases, Fattouma Bourguiba Hospital, Farhat Hached Street 5000, Monastir, Tunisia.
authors.forename: Adnene
authors.initials: A
authors.lastname: Toumi
authors.affiliation: Department of Infectious Diseases, Fattouma Bourguiba Hospital, Farhat Hached Street 5000, Monastir, Tunisia.
authors.forename: Chawki
authors.initials: C
authors.lastname: Loussaief
authors.affiliation: Department of Neurosurgery, Fattouma Bourguiba Hospital, Monastir, Tunisia.
authors.forename: Mohamed Nejib
authors.initials: MN
authors.lastname: Hattab
authors.affiliation: Department of Infectious Diseases, Fattouma Bourguiba Hospital, Farhat Hached Street 5000, Monastir, Tunisia.
authors.forename: Mohamed
authors.initials: M
authors.lastname: Chakroun
mesh_terms: D000151:Acinetobacter Infections / Q000188:drug therapy*; D040981:Acinetobacter baumannii / Q000187:drug effects*; D000328:Adult; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D003091:Colistin; D024901:Drug Resistance, Multiple, Bacterial; D006801:Humans; D008297:Male; D008581:Meningitis / Q000188:drug therapy* / Q000382:microbiology; D008826:Microbial Sensitivity Tests; D008911:Minocycline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D000078304:Tigecycline
chemical_list: D000900:Anti-Bacterial Agents; D000078304:Tigecycline; D008911:Minocycline; D003091:Colistin
keywords: Acinetobacter baumannii; Nosocomial meningitis; Tigecycline