title: Histiocytosis Syndromes Classification, Diagnostic Features and Current Concepts.
abstract: The histiocytosis syndromes are broadly classified as those that feature dendritic cells and those that display only ordinary histiocytes in pathological lesions. The leukemias and lymphomas are malignant but the others defy simple assignment to basic pathological categorization. The ontogeny of histiocytes is considered, Langerhans cell histiocytosis and the hemophagocytic syndromes are discussed in detail and a conceptual context is presented.
authors.affiliation: a I.W.K Hospital for Children, P.O. Box 3070, Halifax, Nova Scotia, Canada, B3J 3G9.
authors.forename: B E
authors.initials: BE
authors.lastname: Favara
keywords: Histiocytosis; Langerhans cells; activation; dendritic cells; histiocytes