title: [A Case of Synchronous Malignant Pheochromocytomas in Bilateral Adrenal Glands].
abstract: We present a case of synchronous malignant pheochromocytoma in bilateral adrenal glands. A 73- year-old man presented to our hospital with bilateral adrenal masses incidentally found during abdominal ultrasonography examination for an unrelated issue. The patient had a 30-year history of hypertension and paroxysmal atrial fibrillation. Computed tomography and magnetic resonance imaging showed heterogeneous tumors in bilateral adrenal glands and an enlarged para-aortic lymph node. Hormonal examinations revealed a high value of urinary catecholamines. Metaiodobenzylguanidine (MIBG) scintigraphy showed increased uptake in bilateral adrenal glands and the lymph node. Both adrenal tumors and the node were surgically removed. Pathological examination revealed histologically distinct tissue between the two adrenal tumors. The patient received five cycles of adjuvant chemotherapy, consisting of cyclophosphamide, vincristine, and dacarbazine. The patient has been in remission for 32 months following surgical treatment.
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Kimitsugu
authors.initials: K
authors.lastname: Usui
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Terukazu
authors.initials: T
authors.lastname: Hirasawa
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Masataka
authors.initials: M
authors.lastname: Kobayashi
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Shioi
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Kazuki
authors.initials: K
authors.lastname: Kobayashi
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Naoki
authors.initials: N
authors.lastname: Sakai
authors.affiliation: The Department of Urology, Yokosuka Kyosai Hospital.
authors.forename: Sumio
authors.initials: S
authors.lastname: Noguchi
authors.affiliation: The Department of Pathology, Yokosuka Kyosai Hospital.
authors.forename: Yukio
authors.initials: Y
authors.lastname: Tsuura
mesh_terms: D000310:Adrenal Gland Neoplasms / Q000188:drug therapy / Q000601:surgery; D000368:Aged; D000971:Antineoplastic Combined Chemotherapy Protocols / Q000627:therapeutic use; D017024:Chemotherapy, Adjuvant; D006801:Humans; D008207:Lymphatic Metastasis; D008297:Male; D009378:Neoplasms, Multiple Primary / Q000188:drug therapy / Q000601:surgery; D010673:Pheochromocytoma / Q000188:drug therapy / Q000601:surgery; D012074:Remission Induction; D016896:Treatment Outcome