title: Molecularly Imprinted Polymer (MIP) Film with Improved Surface Area Developed by Using Metal-Organic Framework (MOF) for Sensitive Lipocalin (NGAL) Determination.
abstract: Electropolymerizable functional and cross-linking monomers were used to prepare conducting molecularly imprinted polymer film with improved surface area with the help of a sacrificial metal-organic framework (MOF). Subsequent dissolution of the MOF layer resulted in a surface developed MIP film. This surface enlargement increased the analyte accessibility to imprinted molecular cavities. Application of the porous MIP film as a recognition unit of an extended-gate field effect transistor (EG-FET) chemosensor effectively enhanced analytical current signals of determination of recombinant human neutrophil gelatinase-associated lipocalin (NGAL).
authors.affiliation: Institute of Physical Chemistry, Polish Academy of Sciences , Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Zofia
authors.initials: Z
authors.lastname: Iskierko
authors.affiliation: Institute of Physical Chemistry, Polish Academy of Sciences , Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Piyush Sindhu
authors.initials: PS
authors.lastname: Sharma
authors.affiliation: Institute of Physical Chemistry, Polish Academy of Sciences , Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Daniel
authors.initials: D
authors.lastname: Prochowicz
authors.affiliation: Institute of Physics, Polish Academy of Sciences , 32/46 Al. Lotników, 02-668 Warsaw, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Fronc
authors.affiliation: Department of Chemistry, University of North Texas , Denton, Texas 76203-5017, United States.
authors.forename: Francis
authors.initials: F
authors.lastname: D'Souza
authors.affiliation: Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw , Ks. Trojdena 4, 02-109 Warsaw, Poland.
authors.forename: Diana
authors.initials: D
authors.lastname: Toczydłowska
authors.affiliation: Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw , Ks. Trojdena 4, 02-109 Warsaw, Poland.
authors.forename: Filip
authors.initials: F
authors.lastname: Stefaniak
authors.affiliation: Institute of Physical Chemistry, Polish Academy of Sciences , Kasprzaka 44/52, 01-224 Warsaw, Poland.
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Noworyta
keywords: EG-FET; NGAL; field effect transistor; human neutrophil gelatinase-associated lipocalin; metal−organic framework; molecular docking; molecularly imprinted polymer