title: A cluster of Enterovirus 71 subgenogroup C2 in a nursery school, Italy, 2014.
abstract: During October 2014, enterovirus (EV) RNA was detected in the stools of four children attending the same class in a nursery school, and hospitalized with mild febrile and vomiting disease in Parma, Italy. Upon sequencing, the viruses were characterized as EV71 subgenogroup C2. Phylogenetic analysis of the four EV71 C2 viruses allowed the distinction of a diverging lineage within subgenogroup C2, containing the Italian EV71 C2 strains and viruses detected in France in 2013. The identification of an outbreak of EV71 C2 in Italy extended information on the geographic diffusion and clinical relevance of these viruses in Europe.
authors.affiliation: Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Medici
authors.affiliation: Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
authors.forename: Fabio
authors.initials: F
authors.lastname: Tummolo
authors.affiliation: Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
authors.forename: Maria Cristina
authors.initials: MC
authors.lastname: Arcangeletti
authors.affiliation: Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
authors.forename: Flora
authors.initials: F
authors.lastname: De Conto
authors.affiliation: Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Chezzi
authors.affiliation: Paediatric Department, University Hospital of Parma, Parma, Italy.
authors.forename: Icilio
authors.initials: I
authors.lastname: Dodi
authors.affiliation: Unit of Microbiology and Virology, Department of Clinical and Experimental Medicine, University of Parma, Parma, Italy.
authors.forename: Adriana
authors.initials: A
authors.lastname: Calderaro
mesh_terms: D002675:Child, Preschool; D029821:Enterovirus A, Human / Q000145:classification* / Q000235:genetics*; D004769:Enterovirus Infections / Q000453:epidemiology* / Q000821:virology*; D006801:Humans; D007558:Italy / Q000453:epidemiology; D008297:Male; D010802:Phylogeny; D012578:Schools, Nursery
keywords: Enterovirus 71; Italy; Outbreak; Phylogenetic analysis; Subgenogroup C2