title: [Dual sensor-controlled rate adaptation in non-dynamical exercise].
abstract: Single sensor and dual sensor systems are used to reach physiological rate adaptation in pacemaker therapy. The purpose of the present study was to examine the sensor-controlled heart rate reaction and adaptability of a dual sensor (QT + activity) with 3 different tests. Nine chronotropically incompetent patients (group 1), 3 females and 6 males, mean age 74.1±8.43 years, were implanted 5 VVIR and 4 DDDR pacemakers (Vitatron, The Netherlands). The control group included 10 chronotropically competent patients (group 2) (2 females, 8 males, mean age 58.2±12.6 years). Both groups underwent 3 different tests: 1) a mental test, 2) an isometric test and 3) an activity (=tap) test. Heart rate was measured every 30 seconds by the recorded surface ECG. We measured an unsatisfaying heart rate response of the pacemaker patients in all 3 tests: During isometric exercise the pacing rate decreased from 63±3.5bpm to 65±3.4bpm (-0.97±0.71bpm/min) (p=0.1829) in contrast to an increase of the heart rate in the control group: from 77.8±15.8bpm to 92.5±19.9bpm (3.76±1.29bpm/min) (p=0.0048). During mental stress testing the pacing rate increased from 63±3.5bpm to 65±3.4bpm (0.66±0.20bpm/min) (p=0.0199) in the pacemaker group, compared to an increase of the heart rate in the control group from 75.8±15.8bpm to 83.6±17.3bpm (2.04±0.74bpm/min) (p=0.0076). Tapping on the pacemaker case produced an increase of the pacing rate from 65.9±2.8bpm to 73.6±3.8bpm (2.83±0.73bpm/min) (p=0.0004), whereas the heart rate decreased from 76.8±13.0bpm to 75.0±1.9bpm (-0.19±0.61bpm/min) (p=0.7522) in the control group. Compared to the physiologically chronotropic function of the control group, the sensor-controlled heart rate response was inadaequate during these tests. The expectations of sensor cross checking could not be fulfilled with the previous sensor combination (QT + activity).
authors.affiliation: Medizinische Klinik II Universitätsklinik Marienhospital Ruhr-Universität Bochum Hölkeskampring 40 44625 Herne, Germany Tel.: +492323-4990 Fax: +492323-499-301 E-Mail: Burkhard.Sievers@ruhr-uni-bochum.de, Germany.
authors.forename: B
authors.initials: B
authors.lastname: Sievers
authors.affiliation: Medizinische Klinik II Universitätsklinik Marienhospital Ruhr-Universität Bochum Hölkeskampring 40 44625 Herne, Germany Tel.: +492323-4990 Fax: +492323-499-301 E-Mail: Burkhard.Sievers@ruhr-uni-bochum.de, Germany.
authors.forename: M
authors.initials: M
authors.lastname: Meine
authors.affiliation: Medizinische Klinik II Universitätsklinik Marienhospital Ruhr-Universität Bochum Hölkeskampring 40 44625 Herne, Germany Tel.: +492323-4990 Fax: +492323-499-301 E-Mail: Burkhard.Sievers@ruhr-uni-bochum.de, Germany.
authors.forename: P
authors.initials: P
authors.lastname: Pfitzner
authors.affiliation: Medizinische Klinik II Universitätsklinik Marienhospital Ruhr-Universität Bochum Hölkeskampring 40 44625 Herne, Germany Tel.: +492323-4990 Fax: +492323-499-301 E-Mail: Burkhard.Sievers@ruhr-uni-bochum.de, Germany.
authors.forename: H J
authors.initials: HJ
authors.lastname: Trappe
keywords: Key words Rate responsive pacemaker; cross checking; dual sensor