title: Apical Functionalization of Tribenzotriquinacenes.
abstract: The introduction of one alkyne moiety at the central carbon atom of the tripodal tribenzotriquinacene scaffold allows easy access to a great variety of apically functionalized derivatives. The spatially well-separated arrangement of different functional units on the convex face and outer rim was further proven by single-crystal X-ray studies. Subsequent modifications that feature a general protecting group-free strategy for the demethylation of protected catechols in the presence of a terminal alkyne group, an azide-alkyne Huisgen cycloaddition, and Sonogashira cross-coupling reactions showcase the high synthetic potential of this modular approach for tribenzotriquinacene derivatization.
authors.affiliation: Universität Würzburg, Institut für Organische Chemie & Center for Nanosystems Chemistry (CNC), Am Hubland, 97074, Würzburg, Germany.
authors.forename: Ayan
authors.initials: A
authors.lastname: Dhara
authors.affiliation: Universität Würzburg, Institut für Organische Chemie & Center for Nanosystems Chemistry (CNC), Am Hubland, 97074, Würzburg, Germany.
authors.forename: Joshua
authors.initials: J
authors.lastname: Weinmann
authors.affiliation: Universität Würzburg, Institut für Organische Chemie & Center for Nanosystems Chemistry (CNC), Am Hubland, 97074, Würzburg, Germany.
authors.forename: Ana-Maria
authors.initials: AM
authors.lastname: Krause
authors.affiliation: Universität Würzburg, Institut für Organische Chemie & Center for Nanosystems Chemistry (CNC), Am Hubland, 97074, Würzburg, Germany. florian.beuerle@uni-wuerzburg.de.
authors.forename: Florian
authors.identifier: http://orcid.org/0000-0001-7239-8327
authors.initials: F
authors.lastname: Beuerle
keywords: Sonogashira cross-coupling; alkynes; bowl-shaped molecules; click chemistry; tribenzotriquinacenes