title: Retinal and choroidal thickness in children with a history of retinopathy of prematurity and transscleral diode laser treatment.
abstract: OBJECTIVE
  To evaluate the outcomes of transscleral diode laser photocoagulation in the eyes of children with a history of threshold retinopathy of prematurity (ROP) and compare them with the eyes of children with no or subthreshold ROP and normal term infants by spectral-domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  Three groups of children aged 4 to 10 years were included as follows: 45 patients with regressed ROP who had not received any treatment (group 1), 48 patients with a history of zone 2 threshold ROP who had been treated with transscleral diode laser (group 2), and 56 age-matched healthy full-term children (group 3). Visual acuity, refractive error, and measurement of retinal and choroidal thickness by SD-OCT were compared between groups retrospectively.
  
  
  RESULTS
  The mean gestational age (GA) and birthweight (BW) were 31 weeks and 1,409 grams in group 1, 28.7 weeks and 1,274.5 grams in group 2, and 38.4 weeks and 3,285 grams in group 3, respectively. There were 6 significant differences in the laser group: GA, BW, macular thickness, foveal depression, spherical equivalent, and visual acuity. In contrast, there were no significant differences among any of the choroidal parameters in all of the groups. Neither macular nor choroidal thickness correlated with visual acuity.
  
  
  CONCLUSIONS
  Although retinal structural changes were observed in patients with a history of ROP, especially in patients treated with laser, no significant difference was found in choroidal thickness between groups. These structural abnormalities may be related to both severity of ROP and laser treatment.
authors.affiliation:  Istanbul Retina Institute, Istanbul - Turkey.
authors.forename: Isıl
authors.initials: I
authors.lastname: Sayman Muslubas
authors.affiliation:  Istanbul Retina Institute, Istanbul - Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Karacorlu
authors.affiliation:  Istanbul Retina Institute, Istanbul - Turkey.
authors.forename: Mumin
authors.initials: M
authors.lastname: Hocaoglu
authors.affiliation:  Istanbul Retina Institute, Istanbul - Turkey.
authors.forename: Serra
authors.initials: S
authors.lastname: Arf
authors.affiliation:  Department of Ophthalmology, Bezmialem Vakif University, School of Medicine, Istanbul - Turkey.
authors.forename: Hakan
authors.initials: H
authors.lastname: Ozdemir
mesh_terms: D001724:Birth Weight; D016022:Case-Control Studies; D002648:Child; D002675:Child, Preschool; D002829:Choroid / Q000000981:diagnostic imaging; D005260:Female; D005584:Fovea Centralis; D005865:Gestational Age; D006801:Humans; D017075:Laser Coagulation / Q000379:methods; D054023:Lasers, Semiconductor / Q000627:therapeutic use*; D008266:Macula Lutea / Q000000981:diagnostic imaging; D008297:Male; D012075:Remission, Spontaneous; D012178:Retinopathy of Prematurity / Q000000981:diagnostic imaging* / Q000628:therapy*; D012189:Retrospective Studies; D041623:Tomography, Optical Coherence; D014792:Visual Acuity / Q000502:physiology