title: The Pattern of Malignant Lymphoma in India: A Study of 1371 Cases.
abstract: A retrospective clinical and histopathological analysis was performed of 1371 patients with Non-Hodgkin's lymphomas presenting between January 1981 and December 1985. Pathologic material was reviewed and classified according to the modified Rappaport classification. The most common histologic type encountered was diffuse histiocytic lymphoma (29.5%), followed by diffuse poorly differentiated lymphoma (28%). A very low incidence of nodular lymphomas (10.6%) was seen. Twenty three percent of the patients had clinically stage 1 disease; 24.6% stage 11; 25.9% stage 111 and 26.2% stage IV disease. Bone marrow involvement was seen in 22.6% of patients. B symptoms were seen in 23.9% of patients. Primary extranodal lymphoma was seen in 307 (22.4%) patients. The commonest site of extranodal involvement was head and neck (36.1%) followed by gastrointestinal tract (24.4%). Treatment results could be analysed in only 599 patients. The response rate was 89% and complete response was seen in 67.5% patients. The overall survival for treated patients was 37.5% after 36 months, which is comparable to that reported by other investigators. This series is compared with different series reported from Asian as well as Western countries in order to highlight some common features as well as other major differences.
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: S H
authors.initials: SH
authors.lastname: Advani
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: S D
authors.initials: SD
authors.lastname: Banavali
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: S
authors.initials: S
authors.lastname: Agarwala
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: R
authors.initials: R
authors.lastname: Gopal
authors.affiliation: b Departments of Medical Radiology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: K A
authors.initials: KA
authors.lastname: Dinshaw
authors.affiliation: c Departments of Medical Pathology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: A
authors.initials: A
authors.lastname: Borges
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: T
authors.initials: T
authors.lastname: Saikia
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: C
authors.initials: C
authors.lastname: Nair
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: P
authors.initials: P
authors.lastname: Kurkure
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: S
authors.initials: S
authors.lastname: Pai
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: V
authors.initials: V
authors.lastname: Pai
authors.affiliation: a Departments of Medical Oncology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: K
authors.initials: K
authors.lastname: Nadakarni
authors.affiliation: b Departments of Medical Radiology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: S
authors.initials: S
authors.lastname: Shrivastava
authors.affiliation: d Departments of Medical Medical Records and Statistics, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: T K
authors.initials: TK
authors.lastname: Shantakumary
authors.affiliation: c Departments of Medical Pathology, Tata Memorial Hospital. Tata Memorial Centre, Parel, Bombay, 400012, India.
authors.forename: D N
authors.initials: DN
authors.lastname: Rao
keywords: Non-Hodgkin's lymphoma; epidemiology of lymphoma; lymphoma