title: Progressive systemic sclerosis with intraoral manifestations: A case report and review.
abstract: The word scleroderma comes from two Greek words, "sclero" meaning hard and "derma" meaning skin. Scleroderma or progressive systemic sclerosis (PSS), a rare condition, was first characterized as a single condition in 1752 by Curzio of Naples. It generally affects woman between 30 and 50 years of age and has a low prevalence. Scleroderma is a disease of the immune system, blood vessels, and connective tissue. Dermal manifestations include stiff, tight, and shiny skin usually of the hands and feet due to swelling and thickening of the connective tissue as they become fibrotic or scarred. Other symptoms include difficulty in swallowing, bloating, abdominal pain, tiredness, lack of energy, weight loss, aching muscles, joints, and bones. The vital organs that may get involved are lungs, heart, and kidneys. We present a case report of PSS in a 45-year-old female patient with characteristic systemic and oral manifestations.
authors.affiliation: Department of Oral Medicine and Radiology, Rama Dental College Hospital and Research Centre, Kanpur, Uttar Pradesh, India.
authors.forename: Rahul
authors.initials: R
authors.lastname: Srivastava
authors.affiliation: Department of Dental Surgery, Ranchi Institute of Neuro-Psychiatry and Allied Sciences, Ranchi, Jharkhand, India.
authors.forename: Bhuvan
authors.initials: B
authors.lastname: Jyoti
authors.affiliation: Department of Physiology, CM Medical College, Durg, Chattisgarh, India.
authors.forename: Manorama
authors.initials: M
authors.lastname: Bihari
authors.affiliation: Department of Oral Pathology and Microbiology, Mansarovar Dental College, Bhopal, Madhya Pradesh, India.
authors.forename: Shobhit
authors.initials: S
authors.lastname: Pradhan
keywords: Immune system; progressive systemic sclerosis; scleroderma