title: Monolithic column incorporated with lanthanide metal-organic framework for capillary electrochromatography.
abstract: A new lanthanide metal-organic frameworks NKU-1 have successfully incorporated into poly (BMA-co-EDMA) monolith and evaluated by capillary electrochromatography (CEC). Lanthanide metal-organic frameworks [Eu2(ABTC)1.5(H2O)3(DMA)] (NKU-1) were synthesized by self-assembly of Eu(III) ions and 3,3',5,5'-azo benzene tetracarboxylic acid ligands have been fabricated into poly(BMA-co-EDMA) monoliths. 1-Butyl-3-methylimidazolium tetrafluoroborate and N,N-dimethylformamide were developed as binary porogen obtaining homogeneous dispersibility for NKU-1 and high permeability for monolithic column. The successful incorporation of NKU-1 into poly(BMA-co-EDMA) was confirmed and characterized by FT-IR spectra, scanning electron microscopy, X-ray diffraction, energy dispersive spectrometer area scanning, and transmission electron microscopy. Separation ability of the NKU-1-poly (BMA-co-EDMA) monoliths was demonstrated by separating four groups of analytes in CEC, including alkylbenzenes, polycyclic aromatic hydrocarbon, aniline series and naphthyl substitutes. Compared with bare monolithic (column efficiency of 100,000plates/m), the NKU-1-poly (BMA-co-EDMA) monoliths have displayed greater column efficiency (maximum 210,000plates/m) and higher permeability, as well as less peak tailing. The results showed that the NKU-1-poly (BMA-co-EDMA) monoliths are promising stationary phases for CEC separations.
authors.affiliation: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
authors.forename: Li-Shun
authors.initials: LS
authors.lastname: Zhang
authors.affiliation: Collaborative Innovation Center of Chemical Science and Engineering, Key Laboratory of Advanced Energy Materials Chemistry (MOE), Department of Chemistry, Nankai University, Tianjin 300071, China.
authors.forename: Pei-Yao
authors.initials: PY
authors.lastname: Du
authors.affiliation: Collaborative Innovation Center of Chemical Science and Engineering, Key Laboratory of Advanced Energy Materials Chemistry (MOE), Department of Chemistry, Nankai University, Tianjin 300071, China. Electronic address: guwen68@nankai.edu.cn.
authors.forename: Wen
authors.initials: W
authors.lastname: Gu
authors.affiliation: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
authors.forename: Qing-Li
authors.initials: QL
authors.lastname: Zhao
authors.affiliation: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China.
authors.forename: Yan-Ping
authors.initials: YP
authors.lastname: Huang
authors.affiliation: Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin 300070, China. Electronic address: zhaoshengliu@sohu.com.
authors.forename: Zhao-Sheng
authors.initials: ZS
authors.lastname: Liu
mesh_terms: D000814:Aniline Compounds / Q000737:chemistry / Q000302:isolation & purification; D053801:Capillary Electrochromatography / Q000379:methods*; D004126:Dimethylformamide / Q000737:chemistry; D007093:Imidazoles / Q000737:chemistry; D028581:Lanthanoid Series Elements / Q000737:chemistry*; D008855:Microscopy, Electron, Scanning; D046529:Microscopy, Electron, Transmission; D010539:Permeability; D011084:Polycyclic Aromatic Hydrocarbons / Q000737:chemistry / Q000302:isolation & purification; D017550:Spectroscopy, Fourier Transform Infrared; D014961:X-Ray Diffraction
chemical_list: C419324:1-butyl-3-methylimidazolium tetrafluoroborate; D000814:Aniline Compounds; D007093:Imidazoles; D028581:Lanthanoid Series Elements; D011084:Polycyclic Aromatic Hydrocarbons; D004126:Dimethylformamide; C023650:aniline
keywords: Capillary electrochromatography; Lanthanide; Metal organic framework; Monolith; Room temperature ionic liquid