title: Assessing ECG signal quality indices to discriminate ECGs with artefacts from pathologically different arrhythmic ECGs.
abstract: False and non-actionable alarms in critical care can be reduced by developing algorithms which assess the trueness of an arrhythmia alarm from a bedside monitor. Computational approaches that automatically identify artefacts in ECG signals are an important branch of physiological signal processing which tries to address this issue. Signal quality indices (SQIs) derived considering differences between artefacts which occur in ECG signals and normal QRS morphology have the potential to discriminate pathologically different arrhythmic ECG segments as artefacts. Using ECG signals from the PhysioNet/Computing in Cardiology Challenge 2015 training set, we studied previously reported ECG SQIs in the scientific literature to differentiate ECG segments with artefacts from arrhythmic ECG segments. We found that the ability of SQIs to discriminate between ECG artefacts and arrhythmic ECG varies based on arrhythmia type since the pathology of each arrhythmic ECG waveform is different. Therefore, to reduce the risk of SQIs classifying arrhythmic events as noise it is important to validate and test SQIs with databases that include arrhythmias. Arrhythmia specific SQIs may also minimize the risk of misclassifying arrhythmic events as noise.
authors.affiliation: Office of Science and Engineering Laboratories, CDRH, US FDA, Silver Spring, MD, USA.
authors.forename: C
authors.initials: C
authors.lastname: Daluwatte
authors.forename: L
authors.initials: L
authors.lastname: Johannesen
authors.forename: L
authors.initials: L
authors.lastname: Galeotti
authors.forename: J
authors.initials: J
authors.lastname: Vicente
authors.forename: D G
authors.initials: DG
authors.lastname: Strauss
authors.forename: C G
authors.initials: CG
authors.lastname: Scully
mesh_terms: D000465:Algorithms; D001145:Arrhythmias, Cardiac / Q000175:diagnosis* / Q000473:pathology / Q000503:physiopathology; D016477:Artifacts; D056902:Clinical Alarms; D004562:Electrocardiography / Q000295:instrumentation; D005189:False Positive Reactions; D006801:Humans; D007362:Intensive Care Units; D008991:Monitoring, Physiologic / Q000295:instrumentation; D011786:Quality Control; D012815:Signal Processing, Computer-Assisted