title: Childhood adversity and insomnia in adolescence.
abstract: The study aims to evaluate the association between exposure to childhood adversity and insomnia, with an emphasis on the role of adversity type, timing, and accumulation (i.e., the number of specific types of adversities the child reported being exposed to).
  
  
  
  Our analytic sample comprised 9582 adolescents from the National Comorbidity Survey Replication Adolescent Supplement (NCS-A), a nationally representative population-based sample. We examined the association between 18 different types of retrospectively reported adversities (capturing interpersonal violence, accidents and injuries, social network or witnessing events, and other adverse events) and risk of self-reported past-year insomnia. We also examined whether the age at first exposure to adversity was associated with the risk of insomnia, and whether exposure to a greater number of different types of adversities (ie, accumulation) conferred an elevated risk of insomnia. In addition, we performed a sensitivity analysis excluding adolescents with a past-year diagnosis of major depression, dysthymia, post-traumatic stress disorder (PTSD), or generalized anxiety disorder.
  
  
  
  Almost one-third of adolescents reported insomnia, with a higher prevalence among girls and those from racial/ethnic minority groups. Adolescents exposed to at least one childhood adversity of any type (59.41%) were more likely than their nonexposed peers to experience insomnia (across adversities, prevalence ratios (PRs) ranged from 1.31 to 1.89). Risk of insomnia differed based on the age at first exposure to adversity as well as the type of adversity. Adolescents exposed to a greater number of different types of adversities had a higher risk of insomnia compared to those experiencing fewer adversities. These results were similar, by and large, to those obtained after excluding adolescents with at least one of the four past-year psychiatric disorders.
  
  
  
  Exposure to adversity confers an elevated risk of insomnia. This association varied by type, timing, and accumulation of exposure and did not appear to be driven by psychiatric disorders. Given the well-documented physical and mental health consequences of insomnia, such findings further support the need for practitioners to screen children for exposure to childhood adversity and insomnia symptoms.
authors.affiliation: Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Yan
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: Miriam R
authors.initials: MR
authors.lastname: Raffeld
authors.affiliation: Department of Epidemiology and Biostatistics, University of Maryland, School of Public Health, College Park, MD, USA.
authors.forename: Natalie
authors.initials: N
authors.lastname: Slopen
authors.affiliation: Program in Public Health, Department of Family, Population, and Preventive Medicine, Stony Brook University, Stony Brook, NY, USA.
authors.forename: Lauren
authors.initials: L
authors.lastname: Hale
authors.affiliation: Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA, USA; Department of Psychiatry, Harvard Medical School, Boston, MA, USA; Stanley Center for Psychiatric Research, The Broad Institute of Harvard and MIT, Boston, MA, USA. Electronic address: edunn2@mgh.harvard.edu.
authors.forename: Erin C
authors.initials: EC
authors.lastname: Dunn
mesh_terms: D000293:Adolescent; D001008:Anxiety Disorders / Q000523:psychology; D002648:Child; D002649:Child Abuse / Q000523:psychology*; D003865:Major Depressive Disorder / Q000523:psychology; D000069581:Exposure to Violence / Q000523:psychology*; D005260:Female; D006801:Humans; D008016:Life Change Events; D008297:Male; D008603:Mental Health; D015995:Prevalence; D012189:Retrospective Studies; D012307:Risk Factors; D012737:Sex Factors; D007319:Sleep Initiation and Maintenance Disorders / Q000453:epidemiology* / Q000208:ethnology; D014481:United States
keywords: Adolescence; Childhood adversity; Epidemiology; Insomnia; Sensitive periods