title: Magnetic resonance angiography: physical principles and applications.
abstract: Magnetic resonance angiography (MRA) is the visualization of hemodynamic flow using imaging techniques that discriminate flowing spins in blood from those in stationary tissue. There are two classes of MRA methods based on whether the magnetic resonance imaging signal in flowing blood is derived from the amplitude of the moving spins, the time-of-flight methods, or is based on the phase accumulated by these flowing spins, as in phase contrast methods. Each method has particular advantages and limitations as an angiographic imaging technique, as evidenced in their application space. Here we discuss the physics of MRA for both classes of imaging techniques, including contrast-enhanced approaches and the recent rapid expansion of the techniques to fast acquisition and processing techniques using parallel imaging coils as well as their application in high-field MR systems such as 3T and 7T.
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston, MA, USA; Department of Biophysics, Harvard University, Cambridge, MA, USA. Electronic address: kiruluta@physics.harvard.edu.
authors.forename: Andrew J M
authors.initials: AJM
authors.lastname: Kiruluta
authors.affiliation: Department of Radiology, Massachusetts General Hospital, Boston, MA, USA.
authors.forename: R Gilberto
authors.initials: RG
authors.lastname: González
mesh_terms: D055592:Biophysical Phenomena; D001921:Brain / Q000098:blood supply / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted; D018810:Magnetic Resonance Angiography; D008279:Magnetic Resonance Imaging; D013997:Time Factors
keywords: MRA; contrast-enhanced; phase contrast; spin saturation; time-of-flight; time-resolved MRA