title: [Intraoperative optical coherence tomography in corneal and glaucoma surgical procedures].
abstract: BACKGROUND
  Optical coherence tomography (OCT) is the clinical gold standard for anterior and posterior segment imaging. Since OCT devices have been integrated into surgical microscopes, this technique is also available intraoperatively in anterior segment surgery. OCT is well established in imaging very thin or transparent structures as they appear in corneal or glaucoma surgery. Therefore, intraoperative OCT can deliver important information for the surgeon which is superior to the normal surgical microscope.
  
  
  OBJECTIVE
  In the present work, an overview about the opportunities of intraoperative OCT in cornea and glaucoma surgery are presented.
  
  
  METHODS
  The recent literature (PubMed) and our own experience at the Center for Ophthalmology, University Hospital of Cologne are analysed.
  
  
  RESULTS
  Intraoperative OCT enables real-time imaging during corneal and glaucoma surgery. Several clinical studies exist, indicating its benefit, e. g. in DMEK, DALK, DSAEK, Boston Keratoprosthesis, canaloplasty or trabectome surgery. Several structures, not visible in the surgical microscope, can be visualized using intraoperative OCT.
  
  
  CONCLUSIONS
  As a real-time and high-resolution imaging device, intraoperative online OCT delivers additional information in glaucoma and corneal surgery, compared to the normal operating microscope. Nonetheless one of the main problems is the shadowing produced by surgical instruments. Today the main limitation is the lack of randomized-controlled clinical trials, evaluating the benefit of microscope-integrated intraoperative OCT, compared to the microscope.
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland. Sebastian.Siebelmann@uk-koeln.de.|Cluster of Excellence: Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Köln, Deutschland. Sebastian.Siebelmann@uk-koeln.de.
authors.forename: S
authors.initials: S
authors.lastname: Siebelmann
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
authors.forename: B
authors.initials: B
authors.lastname: Bachmann
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
authors.forename: A
authors.initials: A
authors.lastname: Lappas
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
authors.forename: T
authors.initials: T
authors.lastname: Dietlein
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
authors.forename: M
authors.initials: M
authors.lastname: Hermann
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
authors.forename: S
authors.initials: S
authors.lastname: Roters
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.
authors.forename: C
authors.initials: C
authors.lastname: Cursiefen
authors.affiliation: Zentrum für Augenheilkunde, Uniklinik Köln, Kerpener Str. 62, 50924, Köln, Deutschland.|Cluster of Excellence: Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Köln, Deutschland.
authors.forename: P
authors.initials: P
authors.lastname: Steven
mesh_terms: D003316:Corneal Diseases / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D016039:Corneal Transplantation / Q000379:methods*; D019317:Evidence-Based Medicine; D005901:Glaucoma / Q000000981:diagnostic imaging* / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D016343:Monitoring, Intraoperative / Q000379:methods; D025321:Surgery, Computer-Assisted / Q000379:methods*; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome
keywords: Canaloplasty; Deep anterior lamellar keratoplasty; Descemet membrane endothelial keratoplasty; Descemet’s stripping automated endothelial keratoplasty; Surgical microscope