title: Development of a Telemetric System for Postoperative Follow-up of Vascular Surgery Procedures: In Vitro Model.
abstract: Because of the unique electromagnetic characteristics of the magnetoelastic microwire, the changes in the pressure of a fluid will provoke a variation of the mechanical pressure on the sensor, which will cause a variation of its magnetization that will be detectable wirelessly. Thus, a wireless system can be developed for following up vascular surgery procedures.
  
  
  
  The sensor consists of a magnetoelastic microwire ring, which was integrated into an in vitro model with pulsatile flow. Different degrees of stenosis were simulated in different locations both in bovine artery as well as in a polytetrafluoroethylene anastomosis. A Fourier analysis of the registered signals and a statistical analysis using Pearson test and receiver operating characteristic (ROC) curves were made. A Pearson index of 0.945 (P<0.001) was obtained between the invasive pressure of the fluid and the power of the signal transmitted by the sensor in bovine artery. The sensor obtained very good ROC curves upon analyzing the signals registered, both in the case of preanastomotic stenosis (area under the curve [AUC], 0.98; 95% CI, 0.97-1.00), of anastomosis (AUC, 0.93; 95% CI, 0.86-0.99), as well as distal (AUC, 0.88; 95% CI, 0.79-0.98), compared to the control group.
  
  
  
  The magnetoelastic microwire has shown that it is capable of detecting, locating, and quantifying the degree of stenosis in bovine artery, as well as in a latero-terminal anastomosis, with a high statistical potency. For the first time, a wireless in vitro sensor has been developed for the postoperative follow-up of vascular surgery procedures.
authors.affiliation: Department of Vascular Surgery, Basurto University Hospital, Universidad País Vasco, Bilbao, Spain mhrydings@hotmail.com.
authors.forename: Manuel
authors.initials: M
authors.lastname: Hernando Rydings
authors.affiliation: Department of Materials Physics, Instituto de Magnetismo Aplicado, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Pilar
authors.initials: P
authors.lastname: Marín Palacios
authors.affiliation: Department of Materials Physics, Instituto de Magnetismo Aplicado, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Ana M
authors.initials: AM
authors.lastname: Aragón-Sánchez
authors.affiliation: Department of Vascular Surgery, Basurto University Hospital, Universidad País Vasco, Bilbao, Spain.
authors.forename: Esther
authors.initials: E
authors.lastname: Bravo Ruiz
authors.affiliation: Department of Materials Physics, Instituto de Magnetismo Aplicado, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Victor
authors.initials: V
authors.lastname: Lopez-Dominguez
authors.affiliation: Department of Angiology and Vascular Surgery, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Isaac
authors.initials: I
authors.lastname: Martínez López
authors.affiliation: Department of Preventive Healthcare, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Cristina
authors.initials: C
authors.lastname: Fernández Pérez
authors.affiliation: Research Unit-Basurto University Hospital- Health services research on chronic patients network (REDISSEC), Bilbao, Spain.
authors.forename: Amaia
authors.initials: A
authors.lastname: Bilbao González
authors.affiliation: Department of Angiology and Vascular Surgery, Hospital Clínico San Carlos, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Francisco Javier
authors.initials: FJ
authors.lastname: Serrano Hernando
authors.affiliation: Department of Vascular Surgery, Basurto University Hospital, Universidad País Vasco, Bilbao, Spain.
authors.forename: Reyes
authors.initials: R
authors.lastname: Vega Manrique
authors.affiliation: Department of Materials Physics, Instituto de Magnetismo Aplicado, Universidad Complutense de Madrid, Madrid, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Hernando Grande
mesh_terms: D000359:Aftercare; D000818:Animals; D019540:Area Under Curve; D001158:Arteries / Q000473:pathology / Q000503:physiopathology*; D002417:Cattle; D003251:Constriction, Pathologic; D060733:Electromagnetic Radiation; D005583:Fourier Analysis; D066298:In Vitro Techniques; D059346:Magnets; D008953:Models, Anatomic; D008955:Models, Cardiovascular; D011138:Polytetrafluoroethylene; D011182:Postoperative Care; D011673:Pulsatile Flow; D012372:ROC Curve; D013686:Telemetry / Q000295:instrumentation*; D014656:Vascular Surgical Procedures; D059015:Wireless Technology / Q000295:instrumentation*
chemical_list: D011138:Polytetrafluoroethylene
keywords: blood pressure; diagnosis; dynamics; follow‐up studies; peripheral vascular disease