title: Lipid Transfer Proteins As Components of the Plant Innate Immune System: Structure, Functions, and Applications.
abstract: Among a variety of molecular factors of the plant innate immune system, small proteins that transfer lipids and exhibit a broad spectrum of biological activities are of particular interest. These are lipid transfer proteins (LTPs). LTPs are interesting to researchers for three main features. The first feature is the ability of plant LTPs to bind and transfer lipids, whereby these proteins got their name and were combined into one class. The second feature is that LTPs are defense proteins that are components of plant innate immunity. The third feature is that LTPs constitute one of the most clinically important classes of plant allergens. In this review, we summarize the available data on the plant LTP structure, biological properties, diversity of functions, mechanisms of action, and practical applications, emphasizing their role in plant physiology and their significance in human life.
authors.affiliation: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya Str. 16/10, 117997 , Moscow, Russia.
authors.forename: E I
authors.initials: EI
authors.lastname: Finkina
authors.affiliation: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya Str. 16/10, 117997 , Moscow, Russia.
authors.forename: D N
authors.initials: DN
authors.lastname: Melnikova
authors.affiliation: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya Str. 16/10, 117997 , Moscow, Russia.
authors.forename: I V
authors.initials: IV
authors.lastname: Bogdanov
authors.affiliation: Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Miklukho-Maklaya Str. 16/10, 117997 , Moscow, Russia.
authors.forename: T V
authors.initials: TV
authors.lastname: Ovchinnikova
keywords: allergens; antimicrobial activity; cross reactivity; lipid binding and transfer; plant defense; plant lipid transfer proteins