title: Intragastric Balloon for Management of Severe Obesity: a Systematic Review.
abstract: Older models of intragastric balloons (IGBs) had unacceptably high complication rates and inconsequential weight loss. With FDA approval of newer models, we aimed to systematically examine the literature regarding the efficacy of IGB therapy for obesity. A comprehensive electronic database search was completed. Title searching was restricted to the following keywords: bariatric, gastric, gastric bypass, gastric band, sleeve gastrectomy, and intragastric balloon. Twenty-six primary studies (n = 6101) were included. At balloon removal, mean change in weight and BMI were 15.7 ± 5.3 kg and 5.9 ± 1.0 kg/m(2). The most common complications were nausea/vomiting (23.3 %) and abdominal pain (19.9 %). Serious complications were rare: mortality (0.05 %) and gastric perforation (0.1 %). IGBs are associated with marked short-term weight loss with limited serious complications.
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.
authors.forename: Ekua
authors.initials: E
authors.lastname: Yorke
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada. nswitzer@ualberta.ca.|2D, Walter C Mackenzie Health Sciences Centre, University of Alberta, 840-112 Street, Edmonton, Alberta, T6G 2B7, Canada. nswitzer@ualberta.ca.
authors.forename: Noah Jacob
authors.initials: NJ
authors.lastname: Switzer
authors.affiliation: Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
authors.forename: Artan
authors.initials: A
authors.lastname: Reso
authors.affiliation: Center for the Advancement of Minimally Invasive Surgery (CAMIS), Royal Alexandria Hospital, Edmonton, Alberta, Canada.
authors.forename: Xinhe
authors.initials: X
authors.lastname: Shi
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.|Center for the Advancement of Minimally Invasive Surgery (CAMIS), Royal Alexandria Hospital, Edmonton, Alberta, Canada.
authors.forename: Christopher
authors.initials: C
authors.lastname: de Gara
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.|Center for the Advancement of Minimally Invasive Surgery (CAMIS), Royal Alexandria Hospital, Edmonton, Alberta, Canada.
authors.forename: Daniel
authors.initials: D
authors.lastname: Birch
authors.affiliation: Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
authors.forename: Richdeep
authors.initials: R
authors.lastname: Gill
authors.affiliation: Department of Surgery, University of Alberta, Edmonton, Alberta, Canada.|Department of Surgery, University of Calgary, Calgary, Alberta, Canada.
authors.forename: Shahzeer
authors.initials: S
authors.lastname: Karmali
mesh_terms: D015905:Gastric Balloon; D006801:Humans; D009767:Obesity, Morbid / Q000601:surgery*; D015431:Weight Loss
keywords: Intragastric balloon; Obesity; Outcomes; Weight loss