title: Can pancreatic tissue cause haemoptysis?
abstract: A mature teratoma is a tumour of primary germ cells. It is often found in the mediastinum. The authors describe a case of a young man who demonstrated haemoptysis as the only symptom of a mediastinal tumour. The tumour was removed operatively, sent for histopathological examination and immunohistochemistry. The removed tumour was a mature teratoma including elements of the pancreas. The authors revealed the presence of trypsin in the pancreatic acinar cells. The proteolytic activity of the tumour was taken as the cause of haemoptysis because of enzymatic erosion of lung tissue intimately attached to the tumour. In such cases surgical removal saves life of patients.
authors.affiliation: muzykantjan@op.pl.
authors.forename: Adam
authors.initials: A
authors.lastname: Bubel
authors.forename: Paweł
authors.initials: P
authors.lastname: Rogoziński
authors.forename: Krzysztof
authors.initials: K
authors.lastname: Bruliński
mesh_terms: D061354:Acinar Cells / Q000201:enzymology / Q000648:ultrastructure; D000328:Adult; D006469:Hemoptysis / Q000209:etiology*; D006801:Humans; D007150:Immunohistochemistry; D008297:Male; D008479:Mediastinal Neoplasms / Q000150:complications* / Q000201:enzymology* / Q000473:pathology / Q000601:surgery; D010179:Pancreas / Q000201:enzymology* / Q000473:pathology; D059748:Proteolysis; D013724:Teratoma / Q000150:complications / Q000201:enzymology* / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed; D014357:Trypsin / Q000378:metabolism*
chemical_list: D014357:Trypsin
keywords: haemoptysis; mediastinal teratoma; pancreatic tissue; proteolysis