title: A genome-wide perspective about the diversity and demographic history of seven Spanish goat breeds.
abstract: The main goal of the current work was to infer the demographic history of seven Spanish goat breeds (Malagueña, Murciano-Granadina, Florida, Palmera, Mallorquina, Bermeya and Blanca de Rasquera) based on genome-wide diversity data generated with the Illumina Goat SNP50 BeadChip (population size, N = 176). Five additional populations from Europe (Saanen and Carpathian) and Africa (Tunisian, Djallonké and Sahel) were also included in this analysis (N = 80) for comparative purposes.
  
  
  
  Our results show that the genetic background of Spanish goats traces back mainly to European breeds although signs of North African admixture were detected in two Andalusian breeds (Malagueña and Murciano-Granadina). In general, observed and expected heterozygosities were quite similar across the seven Spanish goat breeds under analysis irrespective of their population size and conservation status. For the Mallorquina and Blanca de Rasquera breeds, which have suffered strong population declines during the past decades, we observed increased frequencies of large-sized (ROH), a finding that is consistent with recent inbreeding. In contrast, a substantial part of the genome of the Palmera goat breed comprised short ROH, which suggests a strong and ancient founder effect.
  
  
  
  Admixture with African goats, genetic drift and inbreeding have had different effects across the seven Spanish goat breeds analysed in the current work. This has generated distinct patterns of genome-wide diversity that provide new clues about the demographic history of these populations.
authors.affiliation: Department of Animal Genetics, Center for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Campus Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Arianna
authors.initials: A
authors.lastname: Manunza
authors.affiliation: Department of Animal Genetics, Center for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Campus Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Antonia
authors.initials: A
authors.lastname: Noce
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Juan Manuel
authors.initials: JM
authors.lastname: Serradilla
authors.affiliation: Área de Genética y Reproducción Animal, SERIDA-Deva, Camino de Rioseco 1225, Gijón, 33394, Spain.
authors.forename: Félix
authors.initials: F
authors.lastname: Goyache
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Amparo
authors.initials: A
authors.lastname: Martínez
authors.affiliation: Instituto Canario de Investigaciones Agrarias, 38108, La Laguna, Tenerife, Spain.
authors.forename: Juan
authors.initials: J
authors.lastname: Capote
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Juan Vicente
authors.initials: JV
authors.lastname: Delgado
authors.affiliation: Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Jordi
authors.initials: J
authors.lastname: Jordana
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Eva
authors.initials: E
authors.lastname: Muñoz
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Antonio
authors.initials: A
authors.lastname: Molina
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Vincenzo
authors.initials: V
authors.lastname: Landi
authors.affiliation: Unitat de Races Autòctones, Servei de Millora Agrària i Pesquera (SEMILLA), 07198, Son Ferriol, Spain.
authors.forename: Agueda
authors.initials: A
authors.lastname: Pons
authors.affiliation: Faculty of Animal Science and Biotechnologies and Institute of Life Sciences, University of Agricultural Sciences and Veterinary Medicine, 400372, Cluj-Napoca, Romania.
authors.forename: Valentin
authors.initials: V
authors.lastname: Balteanu
authors.affiliation: Institut de l'Environnement et Recherches Agricoles, 04 BP 8645, Ouagadougou 04, Burkina Faso.
authors.forename: Amadou
authors.initials: A
authors.lastname: Traoré
authors.affiliation: Associació de Ramaders de Cabra Blanca de Rasquera, Rasquera, 43513, Spain.
authors.forename: Montse
authors.initials: M
authors.lastname: Vidilla
authors.affiliation: Departamento de Genética, Universidad de Córdoba, 14071, Córdoba, Spain.
authors.forename: Manuel
authors.initials: M
authors.lastname: Sánchez-Rodríguez
authors.affiliation: Department of Animal Genetics, Center for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Campus Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.|Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Armand
authors.initials: A
authors.lastname: Sànchez
authors.affiliation: Department of Animal Genetics, Center for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Campus Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
authors.forename: Tainã Figueiredo
authors.initials: TF
authors.lastname: Cardoso
authors.affiliation: Department of Animal Genetics, Center for Research in Agricultural Genomics (CSIC-IRTA-UAB-UB), Campus Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. marcel.amills@uab.cat.|Departament de Ciència Animal i dels Aliments, Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain. marcel.amills@uab.cat.
authors.forename: Marcel
authors.identifier: 0000-0002-8999-0770
authors.initials: M
authors.lastname: Amills
mesh_terms: D000352:Africa, Northern; D000818:Animals; D001947:Breeding; D005060:Europe; D040961:Genetic Drift; D014644:Genetic Variation; D005828:Genetics, Population; D023281:Genomics; D005838:Genotype; D006041:Goats / Q000235:genetics*; D006579:Heterozygote; D007178:Inbreeding; D011156:Population Density; D013030:Spain