title: Radiosurgery for infundibulum adenoma: stalk dose implications.
abstract: Treating pituitary adenomas in the infundibulum with stereotactic radiosurgery (SRS), achieving tumor volume control while preserving pituitary endocrine function and visual function, is challenging. We present a case of a recurrent remnant infundibular lesion treated with Gamma Knife surgery (GKS). The mass was treated with microsurgical resection twice, and the residual stalk lesion was treated with single-session SRS employing a margin dose of 15 Gy to the infundibulum. Five years after GKS, tumor regression persists without visual dysfunction or hypopituitarism. Radiosurgical doses of 30 Gy to the pituitary stalk may be tolerated by patients while maintaining endocrine function.
authors.affiliation: Department of Neurological Surgery, University of Virginia, PO Box 800212, Charlottesville, VA, 22908, USA. soko@virginia.edu.
authors.forename: Jennifer D
authors.initials: JD
authors.lastname: Sokolowski
authors.affiliation: Department of Neurological Surgery, University of Virginia, PO Box 800212, Charlottesville, VA, 22908, USA.|Department of Neurosurgery, Rambam Health Care Center, Haifa Israel Molecular Immunology &Tumor Immunotherapy Laboratory, Technion Institute of Technology, Haifa, Israel.
authors.forename: Or
authors.initials: O
authors.lastname: Cohen-Inbar
authors.affiliation: Department of Neurological Surgery, University of Virginia, PO Box 800212, Charlottesville, VA, 22908, USA.
authors.forename: Jason P
authors.initials: JP
authors.lastname: Sheehan
mesh_terms: D000236:Adenoma / Q000601:surgery*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010903:Pituitary Gland, Anterior / Q000473:pathology / Q000601:surgery*; D010911:Pituitary Neoplasms / Q000601:surgery*; D011183:Postoperative Complications / Q000209:etiology / Q000517:prevention & control; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods*
keywords: Gamma Knife surgery; Infundibulum; Pituitary adenoma; Pituitary stalk; Stereotactic radiosurgery