title: Therapeutic potential of green tea on risk factors for type 2 diabetes in obese adults - a review.
abstract: Green tea has been associated with positive effects in the treatment of obesity and other associated comorbidities such as type 2 diabetes. These benefits are thought to be related to the anti-inflammatory and antioxidant effects of green tea and to the reduction in body fat percentage exhibited by its bioactive compounds. The predominant active compounds in green tea are flavonoid monomers known as catechins, in particular epigallocatechin-3-gallate, which is the most abundant and most effective catechin in metabolic care, particularly among obese patients. The objective of this review was to investigate the effects of green tea on body composition, oxidative stress, inflammation and insulin resistance, risk factors for the development of type 2 diabetes in obese individuals and the mechanisms that underlie the modulatory actions of green tea compounds on these risk factors. Although green tea has therapeutic potential in the treatment of obese individuals, the findings of this review demonstrate the need for a greater number of studies to confirm the positive effects of green tea, especially regarding the modulation of obesity.
authors.affiliation: Laboratory of Research in Clinical Nutrition and Sports (Labince), Nutrition Faculty, Federal University of Goias (UFG), Goiania, Goias, Brazil.
authors.forename: M A
authors.initials: MA
authors.lastname: Ferreira
authors.affiliation: Laboratory of Research in Clinical Nutrition and Sports (Labince), Nutrition Faculty, Federal University of Goias (UFG), Goiania, Goias, Brazil.
authors.forename: D M
authors.initials: DM
authors.lastname: Silva
authors.affiliation: Laboratory of Research in Clinical Nutrition and Sports (Labince), Nutrition Faculty, Federal University of Goias (UFG), Goiania, Goias, Brazil.
authors.forename: A C
authors.initials: AC
authors.lastname: de Morais
authors.affiliation: Laboratory of Research in Clinical Nutrition and Sports (Labince), Nutrition Faculty, Federal University of Goias (UFG), Goiania, Goias, Brazil.
authors.forename: J F
authors.initials: JF
authors.lastname: Mota
authors.affiliation: Laboratory of Research in Clinical Nutrition and Sports (Labince), Nutrition Faculty, Federal University of Goias (UFG), Goiania, Goias, Brazil.
authors.forename: P B
authors.identifier: 0000-0001-8909-3757
authors.initials: PB
authors.lastname: Botelho
mesh_terms: D000818:Animals; D000975:Antioxidants / Q000494:pharmacology; D001823:Body Composition; D002392:Catechin / Q000031:analogs & derivatives / Q000494:pharmacology; D003924:Diabetes Mellitus, Type 2 / Q000188:drug therapy*; D004195:Disease Models, Animal; D006801:Humans; D007249:Inflammation / Q000188:drug therapy; D007333:Insulin Resistance; D015201:Meta-Analysis as Topic; D009765:Obesity / Q000188:drug therapy*; D018384:Oxidative Stress / Q000502:physiology; D008517:Phytotherapy; D016032:Randomized Controlled Trials as Topic; D012307:Risk Factors; D013662:Tea / Q000737:chemistry*
chemical_list: D000975:Antioxidants; D013662:Tea; D002392:Catechin; C045651:epigallocatechin gallate
keywords: Camellia sinensis; diabetes mellitus; insulin resistance; obesity