title: Overcoming the Limitations of C-H Activation with Strongly Coordinating N-Heterocycles by Cobalt Catalysis.
abstract: Strongly coordinating nitrogen heterocycles, including pyrimidines, oxazolines, pyrazoles, and pyridines, were fully tolerated in cobalt-catalyzed C-H amidations by imidate assistance. Structurally complex quinazolines are thus accessible in a step-economic manner. Our findings also establish the relative powers of directing groups in cobalt(III)-catalyzed C-H functionalization for the first time.
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077, Göttingen, Germany.
authors.forename: Hui
authors.initials: H
authors.lastname: Wang
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077, Göttingen, Germany.
authors.forename: Mélanie M
authors.initials: MM
authors.lastname: Lorion
authors.affiliation: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität Göttingen, Tammannstrasse 2, 37077, Göttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de.
authors.forename: Lutz
authors.identifier: 0000-0001-7034-8772
authors.initials: L
authors.lastname: Ackermann
keywords: C−H activation; cobalt; directing groups; heterocycles; imidates