title: Relation of red cell distribution width with dipper and non-dipper hypertension.
abstract: Aim Red cell distribution width (RDW), an index of erythrocyte size, is associated with high risk for cardiovascular disease. Nondipping hypertension (HT) is lack of nocturnal fall in blood pressure(BP). The association between RDW and non-dipping BP in normotensive and hypertensive patients was investigated. Methods A total of 170 patients were categorized into 4 groups: Normotensive-Dipper (NT-D), Normotensive-Non-dipper (NTND), Hypertensive-Dipper (HT-D) and Hypertensive-Non-dipper(HT-ND). RDW and hs-CRP levels were measured. Results Hypertensive patients had higher RDW and hs-CRP levels(14.5 ± 0.87 vs.12.7 ± 0.66, p<0.001 for RDW; 0.99 ± 0.52 vs.0.63 ± 0.43, p<0.001 for hs-CRP). Besides, the RDW levels were higher in non-dippers (13.0 ± 0.63 vs.12.4 ± 0.55, p<0.001 for NT-ND and NT-D; 14.9 ± 0.78 vs.14.2 ± 0.82, p<0.001 for HT-ND and HT-D) Conclusion RDW is elevated in non-dipping BP both in normotensive and hypertensive subjects, which may be related with increased inflammatory state.
authors.affiliation: Department of Cardiology, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Eyup
authors.initials: E
authors.lastname: Buyukkaya
authors.affiliation: Department of Cardiology, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Ali
authors.initials: A
authors.lastname: Erayman
authors.affiliation: Department of Endocrinology and Metabolism, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Esra
authors.initials: E
authors.lastname: Karakas
authors.affiliation: Department of Cardiology, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Alper
authors.initials: A
authors.lastname: Bugra Nacar
authors.affiliation: Department of Cardiology, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Kurt
authors.affiliation: Department of Cardiology, Antakya State Hospital; Hatay, Turkey.
authors.forename: Sule
authors.initials: S
authors.lastname: Buyukkaya
authors.affiliation: Department of Cardiology, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Adnan
authors.initials: A
authors.lastname: Burak Akcay
authors.affiliation: Department of Cardiology, Mustafa Kemal University, Tayfur Ata Sokmen Medical School, Hatay, Turkey.
authors.forename: Nihat
authors.initials: N
authors.lastname: Sen
mesh_terms: D000328:Adult; D018660:Blood Pressure Monitoring, Ambulatory; D048429:Cell Size; D004909:Erythrocyte Indices; D005260:Female; D006801:Humans; D006973:Hypertension / Q000097:blood* / Q000473:pathology; D008297:Male; D011446:Prospective Studies; D011897:Random Allocation
keywords: blood pressure; circadian rhythm; erythrocyte size; inflammation