title: Subcutaneous Panniculitis-Like T-Cell Lymphoma: A Rare Tumour.
abstract: Subcutaneous Panniculitis like T cell Lymphoma (SPTCL) is an uncommon variant and poorly differentiated type of cutaneous T cell lymphoma. Here we describe the case of a 19-year-old female who presented with swelling of left half of the face with no regional lymphadenopathy and hepatosplenomegaly which was initially misdiagnosed as a benign cutaneous condition by various practitioners. Histopathological examination revealed diffuse infiltration of subcutaneous plane by small to medium sized atypical lymphocytes. Immunohistochemistry showed CD3, CD8 and βF-1 positivity; CD20, CD56, Epstein Barr Virus (EBV) and TCR-δ negativity. Clinical profile, histopathology and immunohistochemical analysis yielded a diagnosis of SPTCL. Thus cases with atypical and nonresolving dermatological lesions should raise a suspicion of SPTCL as diagnosis against other benign conditions.
authors.affiliation: Senior Resident, Department of Medicine, Kasturba Medical College and Hospital , Manipal, Karnataka, India .
authors.forename: Mohan Varadanayakanahalli
authors.initials: MV
authors.lastname: Bhojaraja
authors.affiliation: Junior Resident, Department of Medicine, Kasturba Medical College & Hospital , Manipal, Karnataka India .
authors.forename: Pradeep Kumar Reddy
authors.initials: PK
authors.lastname: Kistampally
authors.affiliation: Assistant Professor, Department of Medical Oncology, Kasturba Medical College & Hospital , Manipal, Karnataka India .
authors.forename: Karthik S
authors.initials: KS
authors.lastname: Udupa
authors.affiliation: Professor, Department of Medicine, Kasturba Medical College & Hospital , Manipal, Karnataka India .
authors.forename: Joseph
authors.initials: J
authors.lastname: Thomas
keywords: Atypical lymphocytes; Cutaneous condition; Face; Non resolving