title: I2/Aqueous TBHP-Catalyzed Coupling of Amides with Methylarenes/Aldehydes/Alcohols: Metal-Free Synthesis of Imides.
abstract: We present a metal-free method for the synthesis of imides by the direct coupling of NH-amides with methylarenes under iodine/aqueous TBHP conditions. The optimized conditions worked very well with benzaldehydes and benzyl alcohol and furnished the corresponding imides in good to excellent yields. A series of control and radical scavenger experiments were also performed, which suggested the involvement of radical pathways. The labeling experiment in the presence of (18)O-labeled H2O suggested water as a source of oxygen in the imides.
authors.affiliation: Academy of Scientific and Innovative Research , Canal Road, Jammu 180001, India.
authors.forename: Hariprasad
authors.initials: H
authors.lastname: Aruri
authors.affiliation: Academy of Scientific and Innovative Research , Canal Road, Jammu 180001, India.
authors.forename: Umed
authors.initials: U
authors.lastname: Singh
authors.affiliation: Academy of Scientific and Innovative Research , Canal Road, Jammu 180001, India.
authors.forename: Sanjay
authors.initials: S
authors.lastname: Kumar
authors.forename: Manoj
authors.initials: M
authors.lastname: Kushwaha
authors.forename: Ajai Prakash
authors.initials: AP
authors.lastname: Gupta
authors.affiliation: Academy of Scientific and Innovative Research , Canal Road, Jammu 180001, India.
authors.forename: Ram A
authors.initials: RA
authors.lastname: Vishwakarma
authors.affiliation: Academy of Scientific and Innovative Research , Canal Road, Jammu 180001, India.
authors.forename: Parvinder Pal
authors.initials: PP
authors.lastname: Singh