title: Predictors of daytime sleepiness in patients with obstructive sleep apnea.
abstract: BACKGROUND
  The main symptomatic criterion to diagnose obstructive sleep apnea (OSA) is the level of daytime sleepiness. The Epworth Sleepiness Scale is a simple, self-administered questionnaire which provides a measurement of the subject's general level of daytime sleepiness. The aim of this study was to investigate the factors that can predict daytime sleepiness in patients with sleep apnea.
  
  
  METHODS
  50 consecutive patients with obstructive sleep apnea were enrolled into the study. Age, gender, anthropometric and polygraphic data were thoroughly analyzed. In all subjects daily sleepiness was assessed by Epworth Sleepiness Scale.
  
  
  RESULTS
  The mean age of the subjects was 54.7 ± 12.8 years, 82% males. The mean BMI was 31.9 ± 6 kg/m2. Pearson correlation coefficient analysis demonstrates a significant positive correlation between the Epworth Sleepiness Scale and the desaturation index (r = 0.31, p < 0.01) and arterial hypertension (r = 0.32, p < 0.01). The forward stepwise regression analysis shows that the apnea hypopnea index and desaturation index are important predictors of daytime sleepiness in patients with obstructive sleep apnea which explains 40% of the Epworth Sleepiness Scale score.
  
  
  CONCLUSIONS
  The desaturation index showed the strongest correlation with the Epworth scale. According to the results of the backward stepwise multiple regression and logistic regression, the predictors for the level of daytime sleepiness are oAHI and index of desaturation. According to the analysis of the ROC curve, desaturation index is a predictor of a high specificity.
authors.forename: Alexandru
authors.initials: A
authors.lastname: Corlateanu
authors.forename: Serghei
authors.initials: S
authors.lastname: Pylchenko
authors.forename: Victoria
authors.initials: V
authors.lastname: Sircu
authors.forename: Victor
authors.initials: V
authors.lastname: Botnaru
mesh_terms: D000328:Adult; D000368:Aged; D015992:Body Mass Index; D006970:Disorders of Excessive Somnolence / Q000175:diagnosis* / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011237:Predictive Value of Tests; D012307:Risk Factors; D012680:Sensitivity and Specificity; D017678:Sex Distribution; D020181:Sleep Apnea, Obstructive / Q000150:complications / Q000175:diagnosis*; D012894:Sleep Stages; D011795:Surveys and Questionnaires; D013997:Time Factors