title: Correlation between CO2 storage at the last minute of gas insufflation and area of retroperitoneal lacuna during retroperitoneal laparoscopic radical nephrectomy.
abstract: Adequate operation interspace is the premise of laparoscopy, and carbon dioxide (CO2) was an ideal gas for forming lacuna. A retroperitoneal space is used to form operation interspace in retroperitoneal laparoscopic radical nephrectomy by making ballooning, and the retroperitoneal space has no relative complete and airtight serous membrane, therefore CO2 absorption may be greater in retroperitoneal than transperitoneal laparoscopic radical nephrectomy. Excess CO2 absorption may induce hypercapnemia and further cause physiopathological change of respiratory and circulatory system. Therefore, exact evaluation of amount of CO2 which is eliminated from body via minute ventilation is important during retroperitoneal laparoscopic radical nephrectomy. The aim of the paper is to study the correlation between CO2 storage at the last minute of gas insufflation and area of retroperitoneal lacuna during retroperitoneal laparoscopic radical nephrectomy.
  
  
  
  Forty ASA I/II patients undergoing retroperitoneal laparoscopic radical nephrectomy were enrolled. CO2 storage at the last minute of gas insufflation and area of a retroperitoneal lacuna were observed. Linear correlation and regression were performed to determine the correlation between them.
  
  
  
  There was positive correlation between CO2 storage at the last minute of gas insufflation and area of retroperitoneal lacuna (r = 0.880, P = 0.000), and the equation of linear regression was y = -83.097 + 0.925x (R(2) = 0.780, t = 11.610, P = 0.000).
  
  
  
  Amount of CO2 which is eliminated from body via mechanical ventilation could be calculated by measuring the area of retroperitoneal lacuna during retroperitoneal laparoscopic radical nephrectomy, and an anesthetist should be aware of the size of lacuna to predict high CO2 storage at the last minute of gas insufflation.
authors.affiliation: Anesthesia Department of Xinjiang Medical University Affiliated Tumor Hospital, No. 789, Suzhoudong Road, Urumqi, 830011, Xinjiang, China.
authors.forename: Jian-Jun
authors.initials: JJ
authors.lastname: Hu
authors.affiliation: Anesthesia Department of Xinjiang Medical University Affiliated Tumor Hospital, No. 789, Suzhoudong Road, Urumqi, 830011, Xinjiang, China.
authors.forename: Ya-Hua
authors.initials: YH
authors.lastname: Liu
authors.affiliation: Anesthesia Department of Xinjiang Medical University Affiliated Tumor Hospital, No. 789, Suzhoudong Road, Urumqi, 830011, Xinjiang, China.
authors.forename: Chan-Juan
authors.initials: CJ
authors.lastname: Yu
authors.affiliation: Anesthesia Department of Xinjiang Medical University Affiliated Tumor Hospital, No. 789, Suzhoudong Road, Urumqi, 830011, Xinjiang, China. yuchanjuan218218@126.com.
authors.forename: Nuerbolati
authors.initials: N
authors.lastname: Jialielihan
mesh_terms: D000328:Adult; D000368:Aged; D002245:Carbon Dioxide / Q000008:administration & dosage / Q000378:metabolism*; D005260:Female; D006801:Humans; D007327:Insufflation; D010535:Laparoscopy / Q000379:methods*; D016014:Linear Models; D008297:Male; D008875:Middle Aged; D009392:Nephrectomy / Q000379:methods*; D012121:Respiration, Artificial; D012187:Retroperitoneal Space; D013997:Time Factors; D055815:Young Adult
chemical_list: D002245:Carbon Dioxide
keywords: CO2 absorption; Correlation; Retroperitoneal lacuna; Retroperitoneal laparoscopic radical nephrectomy