title: The Preparation of Chitosan Oligosaccharide/Alginate Sodium/Gelatin Nanofibers by Spiral-Electrospinning.
abstract: A spiral-electrospinning was used to mass-produce gelatin nanofibers with a content of chitosan oligosaccharide (COS) and alginate sodium (AS). Multiple jets were observed to form on the edges of the helix slice-spinneret simultaneously. Important electrospinning parameters, such as concentration of COS/gelatin aqueous solution, rotational velocity of spinneret and spinning distance, were examined to investigate the electrospinnability of COS/gelatin solution and the morphology of COS/gelatin nanofiber membranes. Due to the poor miscibility between COS and AS, COS/AS/gelatin nanofiber membranes were obtained from COS/gelatin solution and AS/gelatin solution by mixing electrospinning with multi-spinnerets. The novel needleless electrospinning not only avoided the possibility of nozzle-clogging, but also prepared COS/AS/gelatin nanofibers on a large scale for a wide variety of applications.
authors.forename: Weipeng
authors.initials: W
authors.lastname: Lu
authors.forename: Haitao
authors.initials: H
authors.lastname: Xu
authors.forename: Bing
authors.initials: B
authors.lastname: Zhang
authors.forename: Ming
authors.initials: M
authors.lastname: Ma
authors.forename: Yanchuan
authors.initials: Y
authors.lastname: Guo
mesh_terms: D000464:Alginates / Q000737:chemistry*; D048271:Chitosan / Q000737:chemistry*; D005780:Gelatin / Q000737:chemistry*; D020723:Glucuronic Acid / Q000737:chemistry; D006603:Hexuronic Acids / Q000737:chemistry; D008855:Microscopy, Electron, Scanning; D057139:Nanofibers; D009844:Oligosaccharides / Q000737:chemistry*; D017550:Spectroscopy, Fourier Transform Infrared
chemical_list: D000464:Alginates; D006603:Hexuronic Acids; D009844:Oligosaccharides; D020723:Glucuronic Acid; D005780:Gelatin; D048271:Chitosan