title: PreFRP: Prediction and visualization of fluctuation residues in proteins.
abstract: OBJECTIVE
  The PreFRP web server extracts sequence and basic information of a protein structure and groups amino acid residues in a protein into three important types such as high, moderate, and weak fluctuating residues.
  
  
  METHODS
  The server takes a protein data bank file or an amino acid sequence as input and prints the probability of amino acid residues to fluctuate. The server also provides a link to Jmol, a molecular visualization program to visualize the high, moderate, and weak fluctuating residues in three different colors.
  
  
  RESULTS
  Prediction and visualization of fluctuating amino acid residues in proteins may help to understand the complex three-dimensional structure of proteins and may further help in docking and mutation experiments.
  
  
  BACKGROUND
  The web server is freely accessible through the web page of the author's institution http://www.mpi.edu.in/prefrp/link.html.
authors.affiliation: Centre of Excellence in Bioinformatics, School of Biotechnology, Madurai Kamaraj University, Madurai, India.
authors.forename: Konda Mani
authors.initials: KM
authors.lastname: Saravanan
authors.affiliation: Department of Bioinformatics, School of Biosciences, The Marudupandiyar Institutions (Affiliated to Bharathidasan University), Thanjavur, Tamil Nadu, India.
authors.forename: Renganathan
authors.initials: R
authors.lastname: Senthil
keywords: Binding site; carbon content; conformation change; fluctuation residues; intrinsic disorder