title: Superficial Immunity: Antimicrobial Responses Are More Than Skin Deep.
abstract: The skin barrier is essential for host defense, but how the skin provides protection when the barrier is breached is not well understood. In this issue of Immunity, Gallo and colleagues report that keratinocytes integrate signals from antimicrobial peptides via MAVS signaling to amplify their antiviral immune response.
authors.affiliation: Division of Dermatology, Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Box 8123, St. Louis, MO 63110, USA; Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA.
authors.forename: Madison R
authors.initials: MR
authors.lastname: Mack
authors.affiliation: Division of Dermatology, Department of Medicine, Washington University School of Medicine, 660 S. Euclid Avenue, Box 8123, St. Louis, MO 63110, USA; Center for the Study of Itch, Washington University School of Medicine, St. Louis, MO 63110, USA; Division of Biology and Biomedical Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address: briankim@wustl.edu.
authors.forename: Brian S
authors.initials: BS
authors.lastname: Kim
mesh_terms: D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides / Q000276:immunology; D006801:Humans; D007109:Immunity; D007113:Immunity, Innate; D015603:Keratinocytes / Q000276:immunology; D015398:Signal Transduction; D012867:Skin / Q000276:immunology*
chemical_list: D000890:Anti-Infective Agents; D023181:Antimicrobial Cationic Peptides