title: Quantification of the ciliary muscle and crystalline lens interaction during accommodation with synchronous OCT imaging.
abstract: Two SD-OCT systems and a dual channel accommodation target were combined and precisely synchronized to simultaneously image the anterior segment and the ciliary muscle during dynamic accommodation. The imaging system simultaneously generates two synchronized OCT image sequences of the anterior segment and ciliary muscle with an imaging speed of 13 frames per second. The system was used to acquire OCT image sequences of a non-presbyopic and a pre-presbyopic subject accommodating in response to step changes in vergence. The image sequences were processed to extract dynamic morphological data from the crystalline lens and the ciliary muscle. The synchronization between the OCT systems allowed the precise correlation of anatomical changes occurring in the crystalline lens and ciliary muscle at identical time points during accommodation. To describe the dynamic interaction between the crystalline lens and ciliary muscle, we introduce accommodation state diagrams that display the relation between anatomical changes occurring in the accommodating crystalline lens and ciliary muscle.
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Marco
authors.initials: M
authors.lastname: Ruggeri
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Carolina
authors.initials: C
authors.lastname: de Freitas
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami, College of Engineering, Coral Gables, FL, USA.
authors.forename: Siobhan
authors.initials: S
authors.lastname: Williams
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami, College of Engineering, Coral Gables, FL, USA.
authors.forename: Victor M
authors.initials: VM
authors.lastname: Hernandez
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Anne Bates Leach Eye Hospital Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Florence
authors.initials: F
authors.lastname: Cabot
authors.affiliation: Anne Bates Leach Eye Hospital Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Yesilirmak
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Karam
authors.initials: K
authors.lastname: Alawa
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami, College of Engineering, Coral Gables, FL, USA.
authors.forename: Yu-Cherng
authors.initials: YC
authors.lastname: Chang
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Anne Bates Leach Eye Hospital Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Sonia H
authors.initials: SH
authors.lastname: Yoo
authors.affiliation: Quantitative Imaging Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Gregori
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami, College of Engineering, Coral Gables, FL, USA; Vision Cooperative Research Centre, Sydney, NSW, Australia; Brien Holden Vision Institute, Sydney, NSW, Australia.
authors.forename: Jean-Marie
authors.initials: JM
authors.lastname: Parel
authors.affiliation: Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA; Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami, College of Engineering, Coral Gables, FL, USA.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Manns
keywords: (170.4500) Optical coherence tomography; (170.4580) Optical diagnostics for medicine; (330.7322) Visual optics, accommodation; (330.7325) Visual optics, metrology