title: Nonclassical crystallization in vivo et in vitro (I): Process-structure-property relationships of nanogranular biominerals.
abstract: A distinct nanogranular fine structure is shared by a wealth of biominerals from several species, classes and taxa. This nanoscopic organization affects the properties and behavior of the biogenic ceramic material and confers on them attributes that are essential to their function. We present a set of structure-relationship properties that are rooted in the nanogranular organization and we propose that they rest on a common pathway of formation, a colloid-driven and hence nonclassical mode of crystallization. With this common modus operandi, we reveal the most fundamental and wide spread process-structure-property relationship in biominerals. With the recent increase in our understanding of nonclassical crystallization in vitro and in vivo, this significant process-structure-property relationship will serve as a source for new design approaches of bio-inspired materials.
authors.affiliation: Department of Materials Science and Engineering, Institute of Glass and Ceramics (WW3), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Martensstrasse 5, 91058 Erlangen, Germany; Interdisciplinary Center for Functional Particle Systems (FPS), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Haberstrasse 9a, 91058 Erlangen, Germany. Electronic address: stephan.e.wolf@fau.de.
authors.forename: Stephan E
authors.initials: SE
authors.lastname: Wolf
authors.affiliation: Department of Materials Science and Engineering, Institute of Glass and Ceramics (WW3), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Martensstrasse 5, 91058 Erlangen, Germany.
authors.forename: Corinna F
authors.initials: CF
authors.lastname: Böhm
authors.affiliation: Department of Materials Science and Engineering, Institute of Glass and Ceramics (WW3), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Martensstrasse 5, 91058 Erlangen, Germany.
authors.forename: Joe
authors.initials: J
authors.lastname: Harris
authors.affiliation: Department of Materials Science and Engineering, Institute of Glass and Ceramics (WW3), Friedrich-Alexander University Erlangen-Nürnberg (FAU), Martensstrasse 5, 91058 Erlangen, Germany.
authors.forename: Benedikt
authors.initials: B
authors.lastname: Demmert
authors.affiliation: Department of Earth and Planetary Sciences, 16 University Avenue, Macquarie University, NSW 2109, Australia.
authors.forename: Dorrit E
authors.initials: DE
authors.lastname: Jacob
authors.affiliation: Institute of Inorganic and Analytical Chemistry, Johannes Gutenberg-University of Mainz, Duesbergweg 10-14, Germany.
authors.forename: Mihail
authors.initials: M
authors.lastname: Mondeshki
authors.affiliation: Department of Mineralogy and Petrology, University of Granada, Spain, Fuentenueva s/n, 18071 Granada, Spain.
authors.forename: Encarnación
authors.initials: E
authors.lastname: Ruiz-Agudo
authors.affiliation: Department of Mineralogy and Petrology, University of Granada, Spain, Fuentenueva s/n, 18071 Granada, Spain.
authors.forename: Carlos
authors.initials: C
authors.lastname: Rodríguez-Navarro
mesh_terms: D000818:Animals; D002113:Calcification, Physiologic; D003102:Colloids; D003460:Crystallization; D008903:Minerals / Q000737:chemistry / Q000378:metabolism*; D053758:Nanoparticles / Q000737:chemistry*
chemical_list: D003102:Colloids; D008903:Minerals
keywords: ACC; Amorphous calcium carbonate; Biomineralization; Nanoglobules; Nonclassical crystallization; Oriented attachment; PILP