title: Acute Eosinophilic Pneumonia: Pyrethroid Exposure & Change In Smoking Habit!
abstract: We report a case of Acute Eosinophilic Pneumonia (AEP) in a 29-year-old white woman with recent use of a'flea bomb' (containing pyrethroids) at home while remaining indoors, about 48 hours prior to presentation, and recent change in smoking habit (restarted 2 weeks prior after quitting for 10 years). She presented with two days of worsening fever, shortness of breath, productive cough, developed hypoxemic respiratory failure and ARDS. She required a PEEP of 20 and 100% FiO2 to maintain oxygenation. Bronchoalveolar lavage showed 36% Eosinophils. She was given IV steroids with dramatic clinical and radiological improvement. To the best of our knowledge, this is the second report associating AEP with pyrethroid exposure.
authors.forename: Kevin
authors.initials: K
authors.lastname: Kuriakose
authors.forename: Jagpal Singh
authors.initials: JS
authors.lastname: Klair
authors.forename: Andrew
authors.initials: A
authors.lastname: Johnsrud
authors.forename: Nikhil K
authors.initials: NK
authors.lastname: Meena
mesh_terms: D000208:Acute Disease; D000328:Adult; D005260:Female; D058267:Flea Infestations / Q000188:drug therapy*; D006801:Humans; D007306:Insecticides / Q000009:adverse effects*; D011657:Pulmonary Eosinophilia / Q000139:chemically induced* / Q000209:etiology; D011722:Pyrethrins / Q000009:adverse effects*; D012128:Respiratory Distress Syndrome / Q000209:etiology; D012131:Respiratory Insufficiency / Q000209:etiology; D012907:Smoking / Q000009:adverse effects*
chemical_list: D007306:Insecticides; D011722:Pyrethrins