title: Improved vascular healing after the successful treatment of very late sirolimus-eluting stent thrombosis with a bare metal stent implantation - A serial optical coherence tomography study.
abstract: We present the case of a patient with non-ST-elevated myocardial infarction due to very late stent thrombosis 2 years after a sirolimus-eluting stent implantation (SES). Optical coherence tomography (OCT) imaging identified vessel wall destruction of the whole stented coronary segment with multiple cavity formations along the entire stent length, severe strut malapposition and thrombi. The patient was treated successfully with the implantation of a bare metal stent (BMS). Follow-up OCT imaging at 12 months revealed the improvement of vascular healing with complete re-endothelialization of the distal parts of the new BMS, while the stent body remained partly uncovered, suggesting vascular toxicity due to the old SES.
authors.affiliation: Second Department of Cardiology, General Hospital of Nikea, Piraeus, Greece. Electronic address: epapak@tee.gr.
authors.forename: Konstantina P
authors.initials: KP
authors.lastname: Bouki
authors.affiliation: Second Department of Cardiology, General Hospital of Nikea, Piraeus, Greece.
authors.forename: Delia
authors.initials: D
authors.lastname: Vlad
authors.affiliation: First Department of Cardiology, University of Athens Medical School, Athens, Greece.
authors.forename: Maria
authors.initials: M
authors.lastname: Riga
authors.affiliation: Second Department of Cardiology, General Hospital of Nikea, Piraeus, Greece.
authors.forename: Ifigenia
authors.initials: I
authors.lastname: Stergiouli
authors.affiliation: First Department of Cardiology, University of Athens Medical School, Athens, Greece.
authors.forename: Konstantinos P
authors.initials: KP
authors.lastname: Toutouzas
mesh_terms: D000328:Adult; D023903:Coronary Restenosis / Q000000981:diagnostic imaging* / Q000209:etiology; D054855:Drug-Eluting Stents / Q000009:adverse effects*; D006801:Humans; D008297:Male; D000072658:Non-ST Elevated Myocardial Infarction / Q000209:etiology; D020123:Sirolimus / Q000008:administration & dosage; D015607:Stents; D041623:Tomography, Optical Coherence / Q000379:methods*; D016896:Treatment Outcome
chemical_list: D020123:Sirolimus
keywords: Optical coherence tomography; Sirolimus eluting stent; Stent thrombosis; Treatment