title: Specific Blood Pressure Targets for Patients With Diabetic Nephropathy?
abstract: Diabetic nephropathy represents a condition frequently detected in current clinical practice characterized by a very high cardiovascular risk profile. Blood pressure reduction via antihypertension drug treatment represents a therapeutic approach capable of exerting favorable effects on renal and cardiovascular outcomes. The purpose of this article is to review the current literature and results of key clinical trials pertaining to blood pressure goals of antihypertension treatment in these patients. The pros and cons of a less or a more intensive blood pressure goal in diabetic nephropathy will be discussed, with particular emphasis on the cardiovascular and renal effects of each therapeutic strategy.
authors.affiliation: Clinica Medica, University of Milano-Bicocca and Istituto di Ricerche e Cura a Caratttere Scientifico Multimedica, Sesto San Giovanni, Milan, Italy guido.grassi@unimib.it.
authors.forename: Guido
authors.initials: G
authors.lastname: Grassi
authors.affiliation: Istituto Auxologico Italiano and University of Milano-Bicocca, Milan, Italy.
authors.forename: Giuseppe
authors.initials: G
authors.lastname: Mancia
authors.affiliation: Department of Clinical Sciences, Skåne University Hospital, Lund University, Malmö, Sweden.
authors.forename: Peter M
authors.initials: PM
authors.lastname: Nilsson
mesh_terms: D000959:Antihypertensive Agents / Q000627:therapeutic use*; D001794:Blood Pressure / Q000187:drug effects; D002318:Cardiovascular Diseases / Q000188:drug therapy; D003928:Diabetic Nephropathies / Q000150:complications / Q000188:drug therapy* / Q000503:physiopathology*; D006801:Humans; D006973:Hypertension / Q000188:drug therapy; D010347:Patient Care Planning / Q000592:standards; D012307:Risk Factors
chemical_list: D000959:Antihypertensive Agents