title: A non-pharmaceutical form of Artemisia annua is not effective in preventing Plasmodium falciparum malaria.
abstract: Non-pharmaceutical forms of Artemisia annua (a Chinese plant containing artemisinin) are used by some travellers who believe these products are safer than anti-malarial drugs. We report two cases of severe Plasmodium falciparum malaria requiring hospitalization in an Intensive Care Unit following prophylaxis with non-pharmaceutical A. annua in French travellers.
authors.affiliation: Centre Régional de Pharmacovigilance, Service de Pharmacologie-Toxicologie, Chu Angers, 4 rue Larrey 49933 Angers cedex 9, France.
authors.forename: Laurence
authors.initials: L
authors.lastname: Lagarce
authors.affiliation: Département de Réanimation Médicale Et de Médecine Hyperbare, Chu 4 rue Larrey 49933 Angers cedex 9, Angers, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Lerolle
authors.affiliation: Département de Réanimation Médicale Et de Médecine Hyperbare, Chu 4 rue Larrey 49933 Angers cedex 9, Angers, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Asfar
authors.affiliation: Laboratoire de Parasitologie-Mycologie, Chu Angers, 4 rue Larrey 49933 Angers cedex 9, France.
authors.forename: Yohann
authors.initials: Y
authors.lastname: Le Govic
authors.affiliation: Centre Régional de Pharmacovigilance, Service de Pharmacologie-Toxicologie, Chu Angers, 4 rue Larrey 49933 Angers cedex 9, France.
authors.forename: Pascale
authors.initials: P
authors.lastname: Lainé-Cessac
authors.affiliation: Laboratoire de Parasitologie-Mycologie, Chu Angers, 4 rue Larrey 49933 Angers cedex 9, France.
authors.forename: Ludovic
authors.initials: L
authors.lastname: de Gentile
mesh_terms: D000328:Adult; D000962:Antimalarials / Q000008:administration & dosage* / Q000009:adverse effects; D031172:Artemisia annua / Q000009:adverse effects*; D005260:Female; D005602:France; D006760:Hospitalization; D006801:Humans; D016778:Malaria, Falciparum / Q000517:prevention & control*; D008297:Male; D010936:Plant Extracts / Q000008:administration & dosage* / Q000009:adverse effects; D014195:Travel
chemical_list: D000962:Antimalarials; D010936:Plant Extracts