title: Predicting which patients actually receive radiation following breast conserving therapy in Canadian populations.
abstract: Canadian women with breast cancer may choose breast conserving therapy as their course of treatment, requiring both breast conserving surgery and adjuvant radiation therapy. However, more than 15% of Canadian women fail to receive the appropriate radiation therapy, putting them at increased risk for recurrence. Age, distance from their radiation therapy centre and stage of disease affect patients' likelihood of receiving prescribed radiation therapy. We propose a nomogram that allows physicians to predict which patients will and will not receive radiation. This nomogram, once validated, could be used to guide decision making when choosing between breast conserving therapy and mastectomy as the treatment course and thereby change the practice of breast cancer management.
authors.affiliation: From the Schulich School of Medicine & Dentistry, Western University, London, Ont. (Guidolin, Lock, Brackstone); and the London Health Sciences Centre, London, Ont. (Lock, Richard, Boldt, Brackstone).
authors.forename: Keegan
authors.initials: K
authors.lastname: Guidolin
authors.affiliation: From the Schulich School of Medicine & Dentistry, Western University, London, Ont. (Guidolin, Lock, Brackstone); and the London Health Sciences Centre, London, Ont. (Lock, Richard, Boldt, Brackstone).
authors.forename: Michael
authors.initials: M
authors.lastname: Lock
authors.affiliation: From the Schulich School of Medicine & Dentistry, Western University, London, Ont. (Guidolin, Lock, Brackstone); and the London Health Sciences Centre, London, Ont. (Lock, Richard, Boldt, Brackstone).
authors.forename: Lucie
authors.initials: L
authors.lastname: Richard
authors.affiliation: From the Schulich School of Medicine & Dentistry, Western University, London, Ont. (Guidolin, Lock, Brackstone); and the London Health Sciences Centre, London, Ont. (Lock, Richard, Boldt, Brackstone).
authors.forename: Gabriel
authors.initials: G
authors.lastname: Boldt
authors.affiliation: From the Schulich School of Medicine & Dentistry, Western University, London, Ont. (Guidolin, Lock, Brackstone); and the London Health Sciences Centre, London, Ont. (Lock, Richard, Boldt, Brackstone).
authors.forename: Muriel
authors.initials: M
authors.lastname: Brackstone
mesh_terms: D001943:Breast Neoplasms / Q000532:radiotherapy / Q000601:surgery*; D000066491:Clinical Decision-Making / Q000379:methods*; D003661:Decision Support Techniques; D005260:Female; D006801:Humans; D008408:Mastectomy / Q000592:standards*; D015412:Mastectomy, Segmental / Q000592:standards*