title: Diffuse optical tomography using multi-directional sources and detectors.
abstract: Diffuse optical tomography (DOT) is an advanced imaging method used to visualize the internal state of biological tissues as 3D images. However, current continuous-wave DOT requires high-density probe arrays for measurement (less than 15-mm interval) to gather enough information for 3D image reconstruction, which makes the experiment time-consuming. In this paper, we propose a novel DOT measurement system using multi-directional light sources and multi-directional photodetectors instead of high-density probe arrays. We evaluated this system's multi-directional DOT through computer simulation and a phantom experiment. From the results, we achieved DOT with less than 5-mm localization error up to a 15-mm depth with low-density probe arrays (30-mm interval), indicating that the multi-directional measurement approach allows DOT without requiring high-density measurement.
authors.affiliation: ATR Neural Information Analysis Laboratories, Kyoto 619-0288, Japan; These authors contributed equally to this work.
authors.forename: Takeaki
authors.initials: T
authors.lastname: Shimokawa
authors.affiliation: Ricoh Institute of Future Technology, RICOH Company Ltd., Miyagi 981-1241, Japan; These authors contributed equally to this work.
authors.forename: Toshihiro
authors.initials: T
authors.lastname: Ishii
authors.affiliation: Ricoh Institute of Future Technology, RICOH Company Ltd., Miyagi 981-1241, Japan.
authors.forename: Yoichiro
authors.initials: Y
authors.lastname: Takahashi
authors.affiliation: Ricoh Institute of Future Technology, RICOH Company Ltd., Miyagi 981-1241, Japan.
authors.forename: Satoru
authors.initials: S
authors.lastname: Sugawara
authors.affiliation: ATR Neural Information Analysis Laboratories, Kyoto 619-0288, Japan.
authors.forename: Masa-Aki
authors.initials: MA
authors.lastname: Sato
authors.affiliation: ATR Neural Information Analysis Laboratories, Kyoto 619-0288, Japan; Brain Functional Imaging Technologies Group, CiNet, Osaka 565-0871, Japan.
authors.forename: Okito
authors.initials: O
authors.lastname: Yamashita
keywords: (100.3010) Image reconstruction techniques; (110.0113) Imaging through turbid media; (170.3880) Medical and biological imaging