title: Evaluation of the Effect of Attenuation Correction by External CT in a Semiconductor SPECT.
abstract: The discovery of NM530c with a cadmium-zinc-telluride detector (CdZnTe-SPECT) is superior to the conventional Anger-type SPECT with a sodium-iodide detector (NaI-SPECT) in terms of sensitivity and spatial resolution. However, in the clinical example, even in CdZnTe-SPECT, a count decrease in myocardium due to the attenuation of the gamma ray is an issue. This study was conducted to evaluate the effect of computed tomography attenuation correction (CTAC) in CdZnTe-SPECT with the help of external CT. We evaluated the revision effect of uniformity, influence by the difference in attenuation distance, contrast ratio, an uptake rate using the heart phantom. As a result of the phantom studies, a good revision effect was obtained. In the clinical study, there was a statistical significant difference between the contrast ratio before and after CTAC in the inferior wall. In addition, the contrast ratio before and after CTAC in CdZnTe-SPECT image was equal to those of NaI-SPECT image. It was suggested that CTAC using external CT in CdZnTe-SPECT was clinically useful for inferior wall.
authors.affiliation: Department of Radiology, Shimane University Hospital.
authors.forename: Taku
authors.initials: T
authors.lastname: Uchibe
authors.forename: Masahiro
authors.initials: M
authors.lastname: Miyai
authors.forename: Nobuhiro
authors.initials: N
authors.lastname: Yata
authors.forename: Masuo
authors.initials: M
authors.lastname: Haramoto
authors.forename: Yasushi
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Megumi
authors.initials: M
authors.lastname: Nakamura
authors.forename: Hajime
authors.initials: H
authors.lastname: Kitagaki
authors.forename: Yasuyuki
authors.initials: Y
authors.lastname: Takahashi
mesh_terms: D002104:Cadmium; D005260:Female; D006321:Heart / Q000000981:diagnostic imaging*; D006801:Humans; D007091:Image Processing, Computer-Assisted / Q000379:methods; D008297:Male; D019047:Phantoms, Imaging; D011856:Radiographic Image Enhancement / Q000379:methods; D012666:Semiconductors; D012680:Sensitivity and Specificity; D013691:Tellurium; D015899:Tomography, Emission-Computed, Single-Photon / Q000295:instrumentation*; D014057:Tomography, X-Ray Computed / Q000379:methods*; D015032:Zinc
chemical_list: C474490:CdZnTe; D002104:Cadmium; D015032:Zinc; D013691:Tellurium