title: Patient preferences in early glottic cancer treatment.
abstract: Patients with early-stage glottic cancer are primarily treated with one of three options: endoscopic laser excision, external-beam radiation, or open conservation surgery. We sought to determine patient preferences for treatment when presented with a choice between CO2 laser resection and radiation (open conservation surgery was not offered because the endoscopic approach is preferred at our institution). This prospective cohort study was conducted at the Dalhousie University Faculty of Medicine in Halifax, Canada. Our patient population was made up of 54 men and 10 women, aged 30 to 84 years (mean: 65.0 ± 11.2). Their disease were staged as follows: carcinoma in situ, n = 11; T1a = 21; T1b = 6; and T2 = 26. Patients were quoted identical cure rates for the two treatment modalities. The controversial issue of voice outcomes was discussed, but no leading information was given to the study cohort. All 64 patients chose CO2 laser resection as opposed to radiation therapy for definitive treatment.
authors.affiliation: Corresponding author: Michael L. McNeil, MD, Division of Otolaryngology-Head and Neck Surgery, Dalhousie University Faculty of Medicine, Suite 3044 Dickson Bldg., 5820 University Ave., Halifax, NS B3H 1V7, Canada. Email: michaelmcneil@me.com From the Division of Otolaryngology-Head and Neck Surgery, Department of Surgery (Dr. McNeil and Dr. Taylor), and the Department of Radiation Oncology (Dr. Wilke), Dalhousie University Faculty of Medicine, Halifax, Nova Scotia, Canada.
authors.forename: Michael L
authors.initials: ML
authors.lastname: McNeil
authors.forename: Derek R
authors.initials: DR
authors.lastname: Wilke
authors.forename: S Mark
authors.initials: SM
authors.lastname: Taylor
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002170:Canada; D005260:Female; D005931:Glottis / Q000473:pathology / Q000601:surgery; D006801:Humans; D007822:Laryngeal Neoplasms / Q000473:pathology / Q000523:psychology* / Q000601:surgery; D007825:Laryngectomy / Q000379:methods / Q000523:psychology*; D054020:Lasers, Gas / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009367:Neoplasm Staging; D057240:Patient Preference; D011446:Prospective Studies; D050397:Radiotherapy, Intensity-Modulated / Q000379:methods / Q000523:psychology*; D016896:Treatment Outcome