title: Manipulation of host membranes by the bacterial pathogens Listeria, Francisella, Shigella and Yersinia.
abstract: Bacterial pathogens display an impressive arsenal of molecular mechanisms that allow survival in diverse host niches. Subversion of plasma membrane and cytoskeletal functions are common themes associated to infection by both extracellular and intracellular pathogens. Moreover, intracellular pathogens modify the structure/stability of their membrane-bound compartments and escape degradation from phagocytic or autophagic pathways. Here, we review the manipulation of host membranes by Listeria monocytogenes, Francisella tularensis, Shigella flexneri and Yersinia spp. These four bacterial model pathogens exemplify generalized strategies as well as specific features observed during bacterial infection processes.
authors.affiliation: Institut Pasteur, Unit 'Interactions Bactéries Cellules', Paris F-75015, France; INSERM, U604, Paris F-75015, France; INRA, USC2020, Paris F-75015, France. Electronic address: javier.pizarro-cerda@pasteur.fr.
authors.forename: Javier
authors.initials: J
authors.lastname: Pizarro-Cerdá
authors.affiliation: Institut Necker-Enfants Malades, Team 'Pathogénie des Infections Systémiques', Paris F-75015, France; Université Paris Descarte, Sorbonne Paris Cité, Paris F-75015, France; CNRS, UMR8235, Paris F-75015, France; INSERM, U1151, Paris F-75015, France.
authors.forename: Alain
authors.initials: A
authors.lastname: Charbit
authors.affiliation: Institut Pasteur, Unit 'Dynamique des Interactions Hôte-Pathogène', Paris F-75015, France.
authors.forename: Jost
authors.initials: J
authors.lastname: Enninga
authors.affiliation: Institut Pasteur de Lille, Center for Infection and Immunity of Lille, Group 'Cellular Microbiology and Physics of Infection', Lille F-59021, France; Université de Lille, Lille F-59021, France; CNRS, UMR8204, Lille F-59021, France; INSERM, U1019, F-59021 Lille, France; Regional Hospital University Center of Lille, F-59037 Lille, France.
authors.forename: Frank
authors.initials: F
authors.lastname: Lafont
authors.affiliation: Institut Pasteur, Unit 'Interactions Bactéries Cellules', Paris F-75015, France; INSERM, U604, Paris F-75015, France; INRA, USC2020, Paris F-75015, France. Electronic address: pascale.cossart@pasteur.fr.
authors.forename: Pascale
authors.initials: P
authors.lastname: Cossart
mesh_terms: D000818:Animals; D002462:Cell Membrane / Q000382:microbiology*; D005603:Francisella / Q000502:physiology*; D054884:Host-Pathogen Interactions / Q000502:physiology*; D006801:Humans; D008087:Listeria / Q000502:physiology*; D012760:Shigella / Q000502:physiology*; D015007:Yersinia / Q000502:physiology*
keywords: Francisella tularensis; Listeria monocytogenes; Membrane trafficking; Phagocytosis; Shigella flexneri; Yersinia pseudotuberculosis