title: Asymmetric Transamination of α-Keto Acids Catalyzed by Chiral Pyridoxamines.
abstract: A new type of novel chiral pyridoxamines 3a-g containing a side chain has been developed. The pyridoxamines displayed catalytic activity and promising enantioselectivity in biomimetic asymmetric transamination of α-keto acids, to give various α-amino acids in 47-90% yields with up to 87% ee's under very mild conditions. An interesting effect of the side chain on enantioselectivity was observed in the reaction.
authors.affiliation: The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University , Shanghai 200234, P. R. China.
authors.forename: Xiaoyu
authors.initials: X
authors.lastname: Lan
authors.affiliation: The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University , Shanghai 200234, P. R. China.
authors.forename: Chuangan
authors.initials: C
authors.lastname: Tao
authors.affiliation: The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University , Shanghai 200234, P. R. China.
authors.forename: Xuliang
authors.initials: X
authors.lastname: Liu
authors.affiliation: The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University , Shanghai 200234, P. R. China.
authors.forename: Aina
authors.initials: A
authors.lastname: Zhang
authors.affiliation: The Education Ministry Key Lab of Resource Chemistry and Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University , Shanghai 200234, P. R. China.
authors.forename: Baoguo
authors.initials: B
authors.lastname: Zhao