title: Evaluation and management of longitudinally extensive transverse myelitis: a guide for radiologists.
abstract: Longitudinal extensive transverse myelitis (LETM) is defined as an intramedullary spinal cord T2 signal abnormality extending craniocaudally over at least three vertebral bodies on an MRI study. Timely and appropriate diagnosis greatly facilitates patient management. The radiologist should review the relevant clinical information and determine the patient demographics and acuity of symptoms. Herein, we review the spectrum of diseases causing LETM and propose interpretation to guide the radiologist when presented with the MRI finding of LETM.
authors.affiliation: The Russell H. Morgan Department of Radiology, Division of Neuroradiology, Johns Hopkins Hospital School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
authors.forename: S
authors.initials: S
authors.lastname: Mirbagheri
authors.affiliation: Division of Interventional Neuroradiology, Johns Hopkins Hospital, 600 North World Street, Baltimore, MD, USA.
authors.forename: D
authors.initials: D
authors.lastname: Eckart Sorte
authors.affiliation: The Russell H. Morgan Department of Radiology, Division of Neuroradiology, Johns Hopkins Hospital School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
authors.forename: C A
authors.initials: CA
authors.lastname: Zamora
authors.affiliation: Department of Radiology, Division of Neuroradiology, University of Washington, Seattle, WA, USA.
authors.forename: M
authors.initials: M
authors.lastname: Mossa-Basha
authors.affiliation: Department of Neurology, Johns Hopkins Hospital School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA.
authors.forename: S D
authors.initials: SD
authors.lastname: Newsome
authors.affiliation: The Russell H. Morgan Department of Radiology, Division of Neuroradiology, Johns Hopkins Hospital School of Medicine, 600 North Wolfe Street, Baltimore, MD 21287, USA. Electronic address: iizbuda1@jhmi.edu.
authors.forename: I
authors.initials: I
authors.lastname: Izbudak
mesh_terms: D001921:Brain / Q000000981:diagnostic imaging* / Q000473:pathology; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods*; D009188:Myelitis, Transverse / Q000000981:diagnostic imaging* / Q000473:pathology / Q000628:therapy*; D013116:Spinal Cord / Q000000981:diagnostic imaging* / Q000473:pathology