title: The role of radiation therapy in vulvar cancer: review of the current literature.
abstract: The purpose of this article is to discuss the current role of radiation therapy in vulvar cancer and especially to review the recent literature relative to the use of intensity-modulated radiotherapy (IMRT) in disease management. Owing to the low incidence of vulvar cancer, at present there are no available results of cooperative prospective trials. As evidenced in dosimetric and preliminary retrospective clinical studies, the use of IMRT has resulted in superior normal tissue sparing and lower rates of acute and chronic toxicities compared to previous studies that used conventional approaches. Data on long-term outcomes in these patients remain limited.
authors.affiliation:  Radiotherapy Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Piera
authors.initials: P
authors.lastname: Sciacero
authors.affiliation:  Radiotherapy Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Domenico
authors.initials: D
authors.lastname: Cante
authors.affiliation:  Radiotherapy Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Cristina
authors.initials: C
authors.lastname: Piva
authors.affiliation:  Medical Physics Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Valeria
authors.initials: V
authors.lastname: Casanova Borca
authors.affiliation:  Medical Physics Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Edoardo
authors.initials: E
authors.lastname: Petrucci
authors.affiliation:  Medical Physics Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Gastaldi
authors.affiliation:  Radiotherapy Department, Ivrea Community Hospital, ASL TO4, Ivrea (Turin) - Italy.
authors.forename: Maria Rosa
authors.initials: MR
authors.lastname: La Porta
authors.affiliation:  Department of Oncology, Radiation Oncology, University of Turin, Turin - Italy.
authors.forename: Pierfrancesco
authors.initials: P
authors.lastname: Franco
mesh_terms: D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D005260:Female; D006801:Humans; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated; D014846:Vulvar Neoplasms / Q000188:drug therapy / Q000473:pathology / Q000532:radiotherapy*