title: Azole-resistant Candida albicans prosthetic joint infection treated with prolonged administration of anidulafungin and two-stage exchange with implant of a mega-prosthesis.
abstract: Fungal prosthetic joint infection (PJI) is a rare but severe complication of artroplasty. We report a case of PJI due to azole-resistant Candida albicans successfully treated with combination of prolonged administration of anidulafungin and two-stage joint exchange with insertion of a mega-prosthesis.
authors.affiliation: a Malattie Infettive e Ortopedia Settica , Ospedale Santa Maria di Misericordia , Albenga , Savona , Italy.
authors.forename: Giuliana
authors.initials: G
authors.lastname: Carrega
authors.affiliation: a Malattie Infettive e Ortopedia Settica , Ospedale Santa Maria di Misericordia , Albenga , Savona , Italy.
authors.forename: Luca
authors.initials: L
authors.lastname: Cavagnaro
authors.affiliation: a Malattie Infettive e Ortopedia Settica , Ospedale Santa Maria di Misericordia , Albenga , Savona , Italy.
authors.forename: Marco
authors.initials: M
authors.lastname: Basso
authors.affiliation: a Malattie Infettive e Ortopedia Settica , Ospedale Santa Maria di Misericordia , Albenga , Savona , Italy.
authors.forename: Giovanni
authors.initials: G
authors.lastname: Riccio
authors.affiliation: b Laboratory of Microbiology , Ospedale Santa Corona , Pietra Ligure , Savona , Italy.
authors.forename: Agostina
authors.initials: A
authors.lastname: Ronca
authors.affiliation: a Malattie Infettive e Ortopedia Settica , Ospedale Santa Maria di Misericordia , Albenga , Savona , Italy.
authors.forename: Carlo
authors.initials: C
authors.lastname: Salomone
authors.affiliation: a Malattie Infettive e Ortopedia Settica , Ospedale Santa Maria di Misericordia , Albenga , Savona , Italy.
authors.forename: Giorgio
authors.initials: G
authors.lastname: Burastero
mesh_terms: D000368:Aged; D000077612:Anidulafungin; D000935:Antifungal Agents / Q000627:therapeutic use*; D019644:Arthroplasty, Replacement, Hip / Q000009:adverse effects*; D002177:Candidiasis / Q000188:drug therapy*; D025141:Drug Resistance, Fungal; D054714:Echinocandins / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D016459:Prosthesis-Related Infections / Q000382:microbiology* / Q000628:therapy; D012086:Reoperation
chemical_list: D000935:Antifungal Agents; D054714:Echinocandins; D000077612:Anidulafungin
keywords: Anidulafungin; Candida albicans; Mega-prosthesis; Prosthetic joint infection