title: Animal Evolution: The Hard Problem of Cartilage Origins.
abstract: Our skeletons evolved from cartilaginous tissue, but it remains a mystery how cartilage itself first arose in evolution. Characterization of cartilage in cuttlefish and horseshoe crabs reveals surprising commonalities with chordate chondrocytes, suggesting a common evolutionary origin.
authors.affiliation: Developmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, 69017 Heidelberg, Germany. Electronic address: brunet@embl.de.
authors.forename: Thibaut
authors.initials: T
authors.lastname: Brunet
authors.affiliation: Developmental Biology Unit, European Molecular Biology Laboratory, Meyerhofstraße 1, 69017 Heidelberg, Germany. Electronic address: arendt@embl.de.
authors.forename: Detlev
authors.initials: D
authors.lastname: Arendt
mesh_terms: D000818:Animals; D002356:Cartilage; D019902:Chondrocytes; D043344:Chordata