title: Perchlorate Exposure Through Water and Milk in Istanbul.
abstract: Perchlorate is a chemical pollutant that inhibits iodide uptake and may possibly impair thyroid function. Our previous study found widespread perchlorate exposure in non-pregnant, non-lactating, healthy women residing in Istanbul. The aim of this study is to assess the relative amounts of perchlorate exposure attributable to consumption of municipal water, bottled water and boxed milk available in Istanbul. Only trace levels of perchlorate were found in treated municipal water (58 % detectable, mean = 0.13 µg/L, maximum = 0.75 µg/L) and bottled water (7.4 % detectable, mean = <LOD, maximum = 0.19 µg/L). Conversely, all 30 boxed milk samples contained measurable levels of perchlorate (mean = 4.53 µg/L; maximum = 6.21 µg/L). Median perchlorate exposure attributable to water and milk (0.007 µg/kg/day) is small compared both to the reference dose (0.7 µg/kg/day) and to total perchlorate exposure (0.13 µg/kg/day) in Istanbul. Therefore, additional studies are needed to identify the major sources of perchlorate exposure in Istanbul.
authors.affiliation: Department of Medical Engineering, Acibadem University, Istanbul, Turkey.
authors.forename: Ozge
authors.initials: O
authors.lastname: Can
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Ben
authors.initials: B
authors.lastname: Blount
authors.affiliation: Centers for Disease Control and Prevention, Atlanta, GA, USA.
authors.forename: Liza
authors.initials: L
authors.lastname: Valentin-Blasini
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey.
authors.forename: Yigit
authors.initials: Y
authors.lastname: Erdemgil
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey.
authors.forename: Deniz
authors.initials: D
authors.lastname: Uzunoglu
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey.
authors.forename: Murat
authors.initials: M
authors.lastname: Aksoy
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey.
authors.forename: Abdurrahman
authors.initials: A
authors.lastname: Coskun
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey.
authors.forename: Mustafa
authors.initials: M
authors.lastname: Serteser
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey.
authors.forename: Ibrahim
authors.initials: I
authors.lastname: Unsal
authors.affiliation: Department of Medical Biochemistry, School of Medicine, Acibadem University, Kayisdagi Caddesi, No:32, Atasehir, Istanbul, Turkey. aysel.ozpinar@acibadem.edu.tr.
authors.forename: Aysel
authors.initials: A
authors.lastname: Ozpinar
mesh_terms: D000818:Animals; D060766:Drinking Water / Q000737:chemistry*; D004781:Environmental Exposure / Q000032:analysis*; D006801:Humans; D007454:Iodides / Q000378:metabolism; D008892:Milk / Q000737:chemistry*; D010472:Perchlorates / Q000032:analysis*; D014421:Turkey
chemical_list: D060766:Drinking Water; D007454:Iodides; D010472:Perchlorates; C494474:perchlorate
keywords: Iodide; Milk; Nitrate; Perchlorate; Water