title: New polymer for removal of wine phenolics: Poly(N-(3-(N-isobutyrylisobutyramido)-3-oxopropyl)acrylamide) (P-NIOA).
abstract: The phenolic compounds of wine contribute to color and astringency, also are responsible for the oxidation state and bitterness. Due the importance of these molecules, different techniques have been used to modulate their concentration such as natural or synthetic polymeric agents. Among the polymeric agents, PVPP is one of the most used, but lacks of selectivity and has a limited pH range. Therefore, the aim of this study was the synthesis of a new polymer, poly(N-(3-(N-isobutyrylisobutyramido)-3-oxopropyl)acrylamide) (P-NIOA), for removal of phenolic compounds, as a potential agent for the fining of wine. The new polymer affinity was studied using HPLC-DAD for different polyphenols using PVPP as a control. The results showed that the new polymer has a similar removal as PVPP, but with lower affinity to resveratrol. The interactions established between polymers and polyphenols were studied using computational chemistry methods demonstrating a direct correlation with the experimental affinity data.
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile; Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, Talca, Chile.
authors.forename: Ricardo I
authors.initials: RI
authors.lastname: Castro
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile; Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, Talca, Chile.
authors.forename: Oscar
authors.initials: O
authors.lastname: Forero-Doria
authors.affiliation: Department of Clinical Biochemistry and Immunohematology, Faculty of Health Sciences, University of Talca, Talca, Chile; Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, Talca, Chile.
authors.forename: Luis
authors.initials: L
authors.lastname: Guzmán
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile; School of Agricultural Sciences, Universidad de Talca, Chile.
authors.forename: V Felipe
authors.initials: VF
authors.lastname: Laurie
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile.
authors.forename: Oscar
authors.initials: O
authors.lastname: Valdés
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile; Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, Talca, Chile.
authors.forename: Fabián
authors.initials: F
authors.lastname: Ávila-Salas
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile; Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, Talca, Chile.
authors.forename: Xaviera
authors.initials: X
authors.lastname: López-Cortés
authors.affiliation: Nanobiotechnology Division, Fraunhofer Chile Research Foundation - Center for Systems Biotechnology (FCR-CSB), Talca, Maule, Chile; Laboratory of Asymmetric Synthesis, Chemistry Institute of Natural Resources, Universidad de Talca, Talca, Chile. Electronic address: lssantos@utalca.cl.
authors.forename: Leonardo S
authors.initials: LS
authors.lastname: Santos
mesh_terms: D000180:Acrylic Resins / Q000737:chemistry*; D005591:Chemical Fractionation / Q000379:methods*; D059808:Polyphenols / Q000737:chemistry*; D014920:Wine
chemical_list: D000180:Acrylic Resins; D059808:Polyphenols
keywords: Fining; PVPP; Polyphenols; Resveratrol; Wine