title: Sympatho-vagal balance, as quantified by ANSindex, predicts post spinal hypotension and vasopressor requirement in parturients undergoing lower segmental cesarean section: a single blinded prospective observational study.
abstract: Hypotension subsequent to spinal anesthesia occurs in a significant number of parturients undergoing lower segment caesarian section. Currently available methods to predict the incidence of hypotension, its severity and the outcome are sub-optimal. Many workers have used basal heart rate as one of the predictors. But using this method it is not possible to objectively analyze and predict the extent and severity of hypotension. We used an equipment measuring the level of sympatho-vagal balance, ANSiscope™, which derives these values from computed value of RR interval variability. We made a single measure of the value which was blinded to the patient and the anesthesiologist. We studied one hundred eight patients who underwent lower segment caesarian section under spinal anesthesia and found the variability of preoperative ANSindex (% activity displayed by the equipment) from 9 to 65 %. Higher ANSindex value was significantly associated with post spinal hypotension (p 0.017). A value of 24 % indicated the critical level above which hypotension appeared commonly. The ANSindex value might help anesthesiologist to anticipate and prepare for hypotension that is likely to ensue.
authors.affiliation: Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India.
authors.forename: Anitha
authors.initials: A
authors.lastname: Prashanth
authors.affiliation: Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India. mailchakravarthy@gmail.com.
authors.forename: Murali
authors.initials: M
authors.lastname: Chakravarthy
authors.affiliation: Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India.
authors.forename: Antony
authors.initials: A
authors.lastname: George
authors.affiliation: Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India.
authors.forename: Rohini
authors.initials: R
authors.lastname: Mayur
authors.affiliation: Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India.
authors.forename: Rajathadri
authors.initials: R
authors.lastname: Hosur
authors.affiliation: Department of Anesthesia, Critical Care and Pain Relief, Fortis Hospital, Bannerghatta Road, Bengaluru, Karnataka, 560076, India.
authors.forename: Sumant
authors.initials: S
authors.lastname: Pargaonkar
mesh_terms: D000328:Adult; D000773:Anesthesia, Obstetrical; D000775:Anesthesia, Spinal; D000779:Anesthetics, Local / Q000627:therapeutic use; D015992:Body Mass Index; D002045:Bupivacaine / Q000627:therapeutic use; D002585:Cesarean Section; D004562:Electrocardiography; D001330:Electronic Data Processing; D004867:Equipment Design; D005260:Female; D006339:Heart Rate; D006439:Hemodynamics; D006801:Humans; D007022:Hypotension; D016343:Monitoring, Intraoperative; D011247:Pregnancy; D011446:Prospective Studies; D012372:ROC Curve; D015203:Reproducibility of Results; D016037:Single-Blind Method; D013564:Sympathetic Nervous System / Q000503:physiopathology*; D013997:Time Factors; D014630:Vagus Nerve / Q000503:physiopathology*; D014662:Vasoconstrictor Agents / Q000627:therapeutic use
chemical_list: D000779:Anesthetics, Local; D014662:Vasoconstrictor Agents; D002045:Bupivacaine
keywords: Autonomic nervous system; Caesarian section; Hypotension; Prediction; RR interval variation