title: Urinary bladder stone associated with seminal vesicle and prostate infection in a Copenhagen rat.
abstract: We report a very rare case of urinary bladder stone in a laboratory rat, which was associated with severe prostatitis and seminal vesiculitis. Importantly, the histopathological analysis revealed the rare variety of keratinizing desquamative squamous metaplasia of bladder, prostate, and seminal vesicle epithelium. Immunohistochemistry for alpha smooth muscle actin protein and aniline blue staining for collagen clearly showed interstitial prostate fibrosis. The detail information about these findings and subsequent discussion are provided here.
authors.affiliation: Department of Translational Research and Technology Development, Institute of Life Sciences, Tumor Microenvironment and Animal Models Lab, Bhubaneswar, India.
authors.forename: Shantibhusan
authors.initials: S
authors.lastname: Senapati
authors.affiliation: Department of Translational Research and Technology Development, Institute of Life Sciences, Tumor Microenvironment and Animal Models Lab, Bhubaneswar, India; Department of Urology, Manipal University, Manipal, Karnataka, India.
authors.forename: Sujit
authors.initials: S
authors.lastname: Suklabaidya
authors.affiliation: Department of Translational Research and Technology Development, Institute of Life Sciences, Tumor Microenvironment and Animal Models Lab, Bhubaneswar, India.
authors.forename: Hrudananda
authors.initials: H
authors.lastname: Mallik
authors.affiliation: Department of Urology, SCB Medical College, Cuttack, Odisha, India.
authors.forename: Sabyasachi
authors.initials: S
authors.lastname: Panda
authors.affiliation: Department of Urology, SCB Medical College, Cuttack, Odisha, India.
authors.forename: Datteswar
authors.initials: D
authors.lastname: Hota
authors.affiliation: Department of Pathology, Apollo Hospital, Bhubaneswar, Odisha, India.
authors.forename: Manas R
authors.initials: MR
authors.lastname: Baisakh
keywords: Bladder stone; fibrosis; infection; metaplasia; prostate; rat