title: Impact of a Cognitive Behavioral Intervention on Health-Related Quality of Life and General Heart Rate Variability in Patients Following Cardiac Surgery: An Effectiveness Study.
abstract: Although there is evidence supporting the efficacy of cognitive-behavioral therapy (CBT) in decreasing psychologic symptoms and improving health-related quality of life in patients who have undergone coronary artery bypass graft surgery, the effectiveness of these interventions in usual health care practice, and their effect on general heart rate variability (HRV), has not been tested.
  
  
  
  This study investigated the effectiveness of CBT in improving health-related quality of life and HRV in patients with postcardiac surgery.
  
  
  
  However, 2 months following surgery, 150 patients were assigned sequentially to a CBT group that received the intervention for 9 months or a comparison group that received usual care. Patients were assessed at baseline and after 10 months with the 36-item Short Form Health Survey. HRV was also assessed.
  
  
  
  In total, 43 patients in the CBT group and 46 in the usual care group completed the study. The CBT group demonstrated significant improvements in health-related quality of life and significant increases in general HRV. Significant group-by-time interaction effects were found for the several 36-item Short Form Health Survey scales and mental component summary and a time-domain HRV parameter indicating that the pattern of change in scores over time differed significantly between the 2 groups.
  
  
  
  CBT administered in a "real-world" clinical setting can effectively improve health-related quality of life and the general HRV in patients who have undergone cardiac surgery.
authors.affiliation: Laboratory of Clinical Cardiology, Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania. Electronic address: MargaritaBeresnevaite@hotmail.com.
authors.forename: Margarita
authors.initials: M
authors.lastname: Beresnevaitė
authors.affiliation: Laboratory of Clinical Cardiology, Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Rimantas
authors.initials: R
authors.lastname: Benetis
authors.affiliation: Department of Psychiatry, University of Toronto and Mount Sinai Hospital, Toronto, Canada.
authors.forename: Graeme J
authors.initials: GJ
authors.lastname: Taylor
authors.affiliation: Kaunas Vytautas Magnus University, Kaunas, Lithuania.
authors.forename: Svetlana
authors.initials: S
authors.lastname: Rašinskienė
authors.affiliation: Faculty of Medicine, Klaipeda University, Klaipeda, Lithuania.
authors.forename: Albinas
authors.initials: A
authors.lastname: Stankus
authors.affiliation: Laboratory of Clinical Cardiology, Institute of Cardiology, Lithuanian University of Health Sciences, Kaunas, Lithuania.
authors.forename: Sarunas
authors.initials: S
authors.lastname: Kinduris
mesh_terms: D015928:Cognitive Behavioral Therapy / Q000379:methods*; D001026:Coronary Artery Bypass / Q000523:psychology*; D003866:Depressive Disorder / Q000517:prevention & control*; D005260:Female; D006339:Heart Rate; D006801:Humans; D008297:Male; D008875:Middle Aged; D011615:Psychotherapy, Group / Q000379:methods*; D011788:Quality of Life / Q000523:psychology*; D016896:Treatment Outcome
keywords: anxiety; cardiac surgery patients; cognitive behavioral therapy; depression; heart rate variability; quality of life