title: Magnetic navigation system for percutaneous coronary intervention: A meta-analysis.
abstract: BACKGROUND
  Magnetic navigation system (MNS) allows calculation of the vessel coordinates in real space within the patient's chest for percutaneous coronary intervention (PCI). However, its impact on the procedural parameters and clinical outcomes is still a matter of debate. To derive a more precise estimation of the relationship, a meta-analysis was performed.
  
  
  RESULTS
  Studies exploring the advantages of MNS were identified in English-language articles by search of Medline, Web of Science, and Cochrane Library Databases (inception to October 2015). A standardized protocol was used to extract details on study design, region origin, demographic data, lesion type, and clinical outcomes. The main outcome measures were contrast consumption, procedural success rate, contrast used for wire crossing, procedure time to cross the lesions, and the fluoroscopy time fluoroscopy time. A total of 12 clinical trials involving 2174 patients were included for analysis (902 patients in the magnetic PCI group and 1272 in the conventional PCI group). Overall, contrast consumption was decreased by 40.45 mL (95% confidence interval [CI] -70.98 to -9.92, P = 0.009) in magnetic PCI group compared with control group. In addition, magnetic PCI was associated with significantly decreasing procedural time by 2.17 minutes (95% CI -3.91 to -0.44, P = 0.01) and the total fluoroscopy time was significantly decreased by 1.43 minutes (95% CI -2.29 to -0.57, P = 0.001) in magnetic PCI group. However, procedural success rate, contrast used for wire crossing, procedure time to cross the lesions, and the fluoroscopy time to cross the lesions demonstrated that no statistically difference was observed between 2 groups.
  
  
  CONCLUSIONS
  The present meta-analysis indicated an improvement of overall contrast consumption, total procedural time, and fluoroscopy time in magnetic PCI group. However, no significant advantages were observed associated with procedural success rate.
authors.affiliation: Department of Cardiology, Huashan Hospital, Fudan University, Shanghai, China.
authors.forename: Zhiyong
authors.initials: Z
authors.lastname: Qi
authors.forename: Bangwei
authors.initials: B
authors.lastname: Wu
authors.forename: Xinping
authors.initials: X
authors.lastname: Luo
authors.forename: Jun
authors.initials: J
authors.lastname: Zhu
authors.forename: Haiming
authors.initials: H
authors.lastname: Shi
authors.forename: Bo
authors.initials: B
authors.lastname: Jin
mesh_terms: D003287:Contrast Media / Q000008:administration & dosage; D003324:Coronary Artery Disease / Q000000981:diagnostic imaging / Q000601:surgery*; D005471:Fluoroscopy; D006801:Humans; D008280:Magnetics; D061646:Operative Time; D062645:Percutaneous Coronary Intervention / Q000379:methods*
chemical_list: D003287:Contrast Media