title: Triphala, a New Herbal Mouthwash for the Treatment of Gingivitis: A Randomized Controlled Clinical Trial.
abstract: An antiplaque agent with minimal side effects that can be used as an effective adjunct to mechanical plaque control is needed. The current study is designed to evaluate efficacy of triphala (TRP) mouthwash in reduction of plaque and gingivitis.
  
  
  
  Ninety individuals with chronic generalized gingivitis were randomly assigned to three groups: 1) group I, placebo mouthwash; 2) group II, TRP mouthwash; and 3) group III, chlorhexidine (CHX) mouthwash. All individuals were instructed to rinse with their respective mouthwash twice daily. 1) Plaque index (PI); 2) gingival index (GI); 3) oral hygiene index-simplified (OHI-S); and 4) microbiologic colony counts were recorded at baseline and at 7, 30, and 60 days.
  
  
  
  All three groups showed gradual reduction in PI, GI, and OHI-S levels from baseline to 7, 30, and 60 days. There was also significant reduction in microbial counts in all groups at all time intervals except in group I. A significant difference was noticed with respect to reduction in PI, GI, OHI-S, and microbiologic counts in group I compared with groups II and III. However, no significant differences were found between groups II and III for any parameters at any time intervals.
  
  
  
  TRP mouthwash was found to decrease inflammatory parameters from baseline to follow-up intervals. Because improvement in gingivitis was comparable with that of CHX mouthwash, TRP mouthwash can be considered a potential therapeutic agent in the treatment of gingivitis.
authors.affiliation: Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka, India.
authors.forename: A R
authors.initials: AR
authors.lastname: Pradeep
authors.affiliation: Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka, India.
authors.forename: Deepak Kumar
authors.initials: DK
authors.lastname: Suke
authors.affiliation: Department of Periodontology and Oral Implantology, Dr. D.Y. Patil Dental College and Hospital, Pimpri, Pune, Mahrashtra, India.
authors.forename: Santosh S
authors.initials: SS
authors.lastname: Martande
authors.affiliation: Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka, India.
authors.forename: Sonender Pal
authors.initials: SP
authors.lastname: Singh
authors.affiliation: Department of Periodontics, Government Dental College and Research Institute, Bangalore, Karnataka, India.
authors.forename: Kanika
authors.initials: K
authors.lastname: Nagpal
authors.affiliation: Department of Conservative Dentistry and Endodontics, Government Dental College and Research Institute.
authors.forename: Savitha B
authors.initials: SB
authors.lastname: Naik
mesh_terms: D000328:Adult; D002710:Chlorhexidine / Q000627:therapeutic use*; D003773:Dental Plaque; D003774:Dental Plaque Index; D005260:Female; D005891:Gingivitis / Q000178:diet therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009067:Mouthwashes / Q000627:therapeutic use*; D010512:Periodontal Index; D010936:Plant Extracts / Q000627:therapeutic use*
chemical_list: D009067:Mouthwashes; D010936:Plant Extracts; C520904:triphala; D002710:Chlorhexidine
keywords: Chlorhexidine; dental plaque; gingivitis; herbal medicine; mouthwash