title: Major Persistent 5' Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues.
abstract: We performed deep sequencing analysis of the enterovirus 5' noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8.10(2) copies/μg of nucleic acids) and a low viral RNA positive-sense to RNA negative-sense ratio of 4.8.
authors.forename: Alexis
authors.initials: A
authors.lastname: Bouin
authors.forename: Yohan
authors.initials: Y
authors.lastname: Nguyen
authors.forename: Michel
authors.initials: M
authors.lastname: Wehbe
authors.forename: Fanny
authors.initials: F
authors.lastname: Renois
authors.forename: Paul
authors.initials: P
authors.lastname: Fornes
authors.forename: Firouze
authors.initials: F
authors.lastname: Bani-Sadr
authors.forename: Damien
authors.initials: D
authors.lastname: Metz
authors.forename: Laurent
authors.initials: L
authors.lastname: Andreoletti
mesh_terms: D003384:Coxsackievirus Infections / Q000473:pathology / Q000821:virology*; D004252:DNA Mutational Analysis; D004696:Endocarditis / Q000821:virology*; D029822:Enterovirus B, Human / Q000235:genetics*; D005260:Female; D006321:Heart / Q000821:virology*; D006801:Humans; D008875:Middle Aged; D009206:Myocardium / Q000473:pathology*; D012367:RNA, Viral; D017384:Sequence Deletion
chemical_list: D012367:RNA, Viral
keywords: 5′ terminally deleted populations; coxsackievirus B3; endomyocardial; enterovirus; heart; human; idiopathic dilated cardiomyopathy; viruses