title: Palladium-Catalyzed Synthesis of Alkynes via a Tandem Decarboxylation/Elimination of (E)-Enol Triflates.
abstract: A mild catalytic synthesis of alkynes via a tandem Pd-catalyzed decarboxylation/elimination of enol triflates is described. Key attributes of the method include readily available starting materials, broad functional group tolerance, and the ability to access terminal, internal, and halogenated alkynes. The preliminary scope of the reaction is demonstrated on 25 different examples with yields ranging from 63% to 96%.
authors.affiliation: Department of Chemistry, The University of Texas at San Antonio , One UTSA Circle, San Antonio, Texas 78249, United States.
authors.forename: Charissa
authors.initials: C
authors.lastname: Munteanu
authors.affiliation: Department of Chemistry, The University of Texas at San Antonio , One UTSA Circle, San Antonio, Texas 78249, United States.
authors.forename: Doug E
authors.initials: DE
authors.lastname: Frantz
mesh_terms: D000480:Alkynes / Q000138:chemical synthesis* / Q000737:chemistry; D002384:Catalysis; D003653:Decarboxylation; D004952:Esters / Q000737:chemistry*; D008698:Mesylates / Q000737:chemistry*; D015394:Molecular Structure; D010165:Palladium / Q000737:chemistry*
chemical_list: D000480:Alkynes; D004952:Esters; D008698:Mesylates; D010165:Palladium; C012077:trifluoromethanesulfonic acid