title: Association between CT-Diagnosed Pneumonia and Endoscopic Submucosal Dissection of Gastric Neoplasms.
abstract: OBJECTIVE
  This prospective cohort study aimed to elucidate the incidence and characteristics of pneumonia associated with endoscopic submucosal dissection (ESD) of gastric neoplasms using CT.
  
  
  METHODS
  We included consecutive 188 patients with gastric neoplasms treated with ESD. All patients underwent CT before ESD and the day after ESD. Pneumonia associated with ESD was defined as lung ground glass opacity or consolidation by CT the day after ESD.
  
  
  RESULTS
  In 188 patients, 28 patients had diabetes mellitus. Pneumonia was observed by CT in 21 patients (11.2%) after ESD. Of those, 7 patients had diabetes mellitus. By univariate analysis, compared with patients with non-pneumonia complications, risk factors for pneumonia were significantly increased in patients with diabetes mellitus (p = 0.01) and in those who underwent a long procedure time (p = 0.02). By multivariate analysis, pneumonia was significantly increased in patients with diabetes mellitus (OR 4.06, 95% CI 1.35-12.19) and in those who underwent a long procedure time (OR 1.01, 95% CI 1.00-1.02).
  
  
  CONCLUSIONS
  The incidence of CT-diagnosed pneumonia associated with ESD was relatively high. Furthermore, it was revealed that diabetes mellitus and a long procedure time were risk factors of CT-diagnosed pneumonia.
authors.affiliation: Department of Gastroenterology, National Hospital Organization, Fukuyama Medical Center, Hiroshima, Japan.
authors.forename: Isao
authors.initials: I
authors.lastname: Fujita
authors.forename: Tatsuya
authors.initials: T
authors.lastname: Toyokawa
authors.forename: Katsunori
authors.initials: K
authors.lastname: Matsueda
authors.forename: Shizuma
authors.initials: S
authors.lastname: Omote
authors.forename: Akiko
authors.initials: A
authors.lastname: Fujita
authors.forename: Yuya
authors.initials: Y
authors.lastname: Ueda
authors.forename: Shinya
authors.initials: S
authors.lastname: Endo
authors.forename: Rika
authors.initials: R
authors.lastname: Omote
authors.forename: Kazuo
authors.initials: K
authors.lastname: Watanabe
authors.forename: Joichiro
authors.initials: J
authors.lastname: Horii
authors.forename: Takako
authors.initials: T
authors.lastname: Murakami
authors.forename: Jun
authors.initials: J
authors.lastname: Tomoda
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003924:Diabetes Mellitus, Type 2 / Q000150:complications; D000069916:Endoscopic Mucosal Resection / Q000009:adverse effects*; D005260:Female; D005753:Gastric Mucosa / Q000601:surgery*; D006801:Humans; D015994:Incidence; D007564:Japan / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D061646:Operative Time; D011015:Pneumonia, Aspiration / Q000000981:diagnostic imaging* / Q000453:epidemiology; D011183:Postoperative Complications / Q000000981:diagnostic imaging* / Q000453:epidemiology; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D013274:Stomach Neoplasms / Q000453:epidemiology / Q000601:surgery*; D014057:Tomography, X-Ray Computed