title: Depth-resolved measurements with elliptically polarized reflectance spectroscopy.
abstract: The ability of elliptical polarized reflectance spectroscopy (EPRS) to detect spectroscopic alterations in tissue mimicking phantoms and in biological tissue in situ is demonstrated. It is shown that there is a linear relationship between light penetration depth and ellipticity. This dependence is used to demonstrate the feasibility of a depth-resolved spectroscopic imaging using EPRS. The advantages and drawbacks of EPRS in evaluation of biological tissue are analyzed and discussed.
authors.affiliation: Department of Imaging Physics, MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA.
authors.forename: Maria J
authors.initials: MJ
authors.lastname: Bailey
authors.affiliation: Department of Imaging Physics, MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX 78712, USA; Department of Bioengineering, Rice University, Houston, TX 77005, USA.
authors.forename: Konstantin
authors.initials: K
authors.lastname: Sokolov
keywords: (170.6510) Spectroscopy, tissue diagnostics; (290.0290) Scattering; (290.5855) Scattering, polarization; (300.0300) Spectroscopy