title: Effects of antibacterial coating on monomer exudation and the mechanical properties of denture base resins.
abstract: BACKGROUND
  Denture base resin may be exposed to different conditions for long periods, resulting in the loss of monomer by exudation and a decrease in mechanical properties.
  
  
  OBJECTIVE
  The purpose of this in vitro study was to evaluate monomer loss by exudation from denture base resins doped with antibacterial coatings and their mechanical properties after long-term water immersion.
  
  
  METHODS
  Four kinds of dental base resin materials were used as experimental materials. The specimens of each resin were divided into an experimental group (coated) and a control group (uncoated). Monomer exudation was tested at 7 and 28 days by gas chromatography after materials were immersed in distilled water or a solution of 75% alcohol/distilled water. Flexural strength and elastic modulus were tested with a universal testing machine after immersion for 2 and 180 days. The surface morphology was characterized with atomic force microscopy. The data were analyzed using 3-way ANOVA followed by the Tukey-Kramer honest significant difference test (α=.05).
  
  
  RESULTS
  In both of the immersion media, each of the 3 factors (materials, coating, and immersion time) significantly affected the monomer exudation (P<.05). In addition, the interaction between any 2 of those factors or among the 3 factors had a significant interaction effect on the monomer exudation of the denture base (P<.05). The mechanical properties of the tested materials were different, and the immersion time had a significant effect on the flexural properties (P<.05). For flexural strength, a significant interaction effect occurred among the 3 factors (material, coating, and immersion time) (P<.05). The coating has a significant effect on the elastic modulus of denture base resin (P<.05) and on the interaction between the material and immersion time (P<.05).
  
  
  CONCLUSIONS
  The silver-loaded mesoporous silica antibacterial coating can effectively reduce monomer exudation and enhance the flexural properties of denture base resin after immersion.
authors.affiliation: Postgraduate student, Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Jilin, People's Republic of China.
authors.forename: Dan
authors.initials: D
authors.lastname: Feng
authors.affiliation: Postgraduate student, Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Jilin, People's Republic of China.
authors.forename: Haihuan
authors.initials: H
authors.lastname: Gong
authors.affiliation: Postgraduate student, Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Jilin, People's Republic of China.
authors.forename: Jiahui
authors.initials: J
authors.lastname: Zhang
authors.affiliation: Postgraduate student, Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Jilin, People's Republic of China.
authors.forename: Xiaowei
authors.initials: X
authors.lastname: Guo
authors.affiliation: Postgraduate student, Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Jilin, People's Republic of China.
authors.forename: Min
authors.initials: M
authors.lastname: Yan
authors.affiliation: Professor, Department of Prosthodontics, School and Hospital of Stomatology, Jilin University, Jilin, People's Republic of China. Electronic address: zhusong1965@163.com.
authors.forename: Song
authors.initials: S
authors.lastname: Zhu
mesh_terms: D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000627:therapeutic use*; D001696:Biomechanical Phenomena; D002849:Chromatography, Gas; D019232:Dental Restoration Failure; D003819:Denture Bases; D055119:Elastic Modulus; D066298:In Vitro Techniques; D020366:Methylmethacrylate / Q000032:analysis; D012117:Resins, Synthetic / Q000627:therapeutic use*; D013718:Tensile Strength
chemical_list: D000900:Anti-Bacterial Agents; D012117:Resins, Synthetic; D020366:Methylmethacrylate