title: Background and Epidemiology.
abstract: Cystic fibrosis (CF) is the most common autosomal-recessive disease in white persons. Significant advances in therapies and outcomes have occurred for people with CF over the past 30 years. Many of these improvements have come about through the concerted efforts of the CF Foundation and international CF societies; networks of CF care centers; and the worldwide community of care providers, researchers, and patients and families. There are still hurdles to overcome to continue to improve the quality of life, reduce CF complications, prolong survival, and ultimately cure CF. This article reviews the epidemiology of CF, including trends in incidence and prevalence, clinical characteristics, common complications, and survival.
authors.affiliation: Department of Pediatrics, Riley Hospital for Children at IU Health, Indiana University, 705 Riley Hospital Drive, Suite 4270, Indianapolis, IN 46202, USA. Electronic address: dbsand@iu.edu.
authors.forename: Don B
authors.initials: DB
authors.lastname: Sanders
authors.affiliation: Cystic Fibrosis Foundation, 6931 Arlington Road, Bethesda, MD 20814, USA.
authors.forename: Aliza K
authors.initials: AK
authors.lastname: Fink
mesh_terms: D000328:Adult; D002648:Child; D002675:Child, Preschool; D003550:Cystic Fibrosis / Q000150:complications / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D015997:Neonatal Screening; D015995:Prevalence; D015996:Survival Rate
keywords: BMI; Cystic fibrosis; FEV(1); MRSA; Mortality; Newborn screening; Pseudomonas aeruginosa