title: Long-Term Use and Safety of Migraine Preventive Medications.
abstract: Migraine preventive medications are used to reduce the frequency, severity, and disability of migraine attacks. Once migraine preventive therapy is initiated, the question of how long to maintain this therapy arises. This article will explore the literature pertaining to the long-term use of migraine preventive medications, including length of treatment and safety with long-term exposure.
authors.affiliation: Department of Neurology, Mayo Clinic, Phoenix, AZ, USA.
authors.forename: Juliana
authors.initials: J
authors.lastname: VanderPluym
authors.affiliation: Department of Neurology, Baylor College of Medicine, Houston, TX, USA.
authors.forename: Randolph W
authors.initials: RW
authors.lastname: Evans
authors.affiliation: Department of Neurology, Mayo Clinic, Phoenix, AZ, USA. starling.amaal@mayo.edu.
authors.forename: Amaal J
authors.initials: AJ
authors.lastname: Starling
mesh_terms: D000328:Adult; D002491:Central Nervous System Agents / Q000009:adverse effects* / Q000627:therapeutic use*; D005260:Female; D006801:Humans; D008881:Migraine Disorders / Q000517:prevention & control*
chemical_list: D002491:Central Nervous System Agents
keywords: anticonvulsants; antidepressants; beta blockers; headache; migraine; preventive therapy