title: [Recurrence of drug eruption after renewed injection of iodinated contrast medium in patients with known allergic contraindications].
abstract: BACKGROUND
  Iodinated contrast media (ICM) are used extensively by both radiologists and cardiologists. Injection of such products can induce immediate hypersensitivity reactions, some of which are IgE-mediated, and delayed hypersensitivity reaction with all types of drug eruptions being reported. Allergy tests, whether patch-tests or intradermal tests, are useful to confirm whether patients are allergic. At the end of these tests, depending on the reaction (chronology and clinical symptoms) and the results of the skin tests, patients are given an allergy card as well as a detailed certificate indicating the various ICM contraindicated and those allowed.
  
  
  METHODS
  We report herein three cases of patients experiencing a confirmed allergic eruption after injection of ICM, and whose recommendations and contraindication were not taken into consideration, leading to recurrence of eruption after renewed ICM injection.
  
  
  CONCLUSIONS
  The three cases we report herein underscore the lack of knowledge concerning eruptions induced by ICM, particularly among radiologists. Better dissemination of information about the existence of such reactions appears necessary amongst the medical professionals concerned.
authors.affiliation: Service de dermatologie et allergologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France. Electronic address: emmanuelle.amsler@tnn.aphp.fr.
authors.forename: E
authors.initials: E
authors.lastname: Amsler
authors.affiliation: Service de dermatologie et allergologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France.
authors.forename: J-E
authors.initials: JE
authors.lastname: Autegarden
authors.affiliation: Service de dermatologie et allergologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France.
authors.forename: P
authors.initials: P
authors.lastname: Senet
authors.affiliation: Service de dermatologie et allergologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France.
authors.forename: C
authors.initials: C
authors.lastname: Frances
authors.affiliation: Service de dermatologie et allergologie, hôpital Tenon, 4, rue de la Chine, 75020 Paris, France; Immunology and infectious diseases center-Paris (Cimi-Paris), Inserm U1135, Sorbonne university, UPMC université Paris 06, 75013 Paris, France.
authors.forename: A
authors.initials: A
authors.lastname: Soria
mesh_terms: D003287:Contrast Media / Q000009:adverse effects*; D003875:Drug Eruptions / Q000209:etiology*; D063926:Drug Hypersensitivity Syndrome / Q000209:etiology; D005260:Female; D006801:Humans; D008297:Male; D010328:Patch Tests; D012008:Recurrence
chemical_list: D003287:Contrast Media
keywords: Delayed hypersensitivity; Drug eruption; Hypersensibilité retardée; Iodinated contrast media; Produit de contraste iodé; Toxidermie