title: Severe West Nile virus meningoencephalitis in a pediatric renal transplant recipient: successful recovery and long-term neuropsychological outcome.
abstract: West Nile Virus is an arbovirus that has rapidly spread throughout the United States since the first case was described in Queens, New York in 1999. There has been increasing reports of both community-acquired and organ-derived infections in renal transplant recipients. In immunocompromised individuals, WNV infection is a life-threatening disease with significant neurological morbidity. We report the only pediatric case of community-acquired WNV disease in a renal transplant recipient to undergo detailed long-term neuropsychological assessment. Increased surveillance and prompt treatment of WNV meningoencephalitis is critical, and our report highlights the effectiveness of immunosuppression reduction without compromising allograft outcomes.
authors.affiliation: Louisiana State University Health Sciences Center, New Orleans, LA, USA.
authors.forename: S L
authors.initials: SL
authors.lastname: Lambert
authors.affiliation: Louisiana State University Health Sciences Center, New Orleans, LA, USA.|Nephrology, Children's Hospital of New Orleans, New Orleans, LA, USA.
authors.forename: D
authors.initials: D
authors.lastname: Aviles
authors.affiliation: Louisiana State University Health Sciences Center, New Orleans, LA, USA.
authors.forename: V M
authors.initials: VM
authors.lastname: Vehaskari
authors.affiliation: Nephrology, Children's Hospital of New Orleans, New Orleans, LA, USA.
authors.forename: I F
authors.initials: IF
authors.lastname: Ashoor
mesh_terms: D002648:Child; D006801:Humans; D016867:Immunocompromised Host; D016030:Kidney Transplantation; D008297:Male; D008590:Meningoencephalitis / Q000175:diagnosis* / Q000276:immunology; D009483:Neuropsychological Tests; D011183:Postoperative Complications / Q000175:diagnosis* / Q000276:immunology; D012720:Severity of Illness Index; D014901:West Nile Fever / Q000175:diagnosis* / Q000276:immunology
keywords: Encephalitis; West Nile virus; pediatric kidney transplant