title: [ROLE OF VAGOINSULAR AND ENTERIC ENDOCRINE SYSTEMS IN ACUTE GASTRODUODENAL EROSION AND ULCERS FORMATION IN SEVERE COMBINED TRAUMATIC BRAIN INJURY DEPENDING ON THE COMBINATION OF DAMAGE].
abstract: 347 patients were analyzed and role of vagoinsular and enteric endocrine systems in acute gastroduodenal erosion and ulcers formation in severe traumatic brain injury were assessed depending on the combination of TBI with various organs and systems damage. It was revealed that activation ofvagoinsular and enteric endocrine systems due to microcirculatory disorders and hypoxia associated with severe TBI plays a crucial role in increasing the frequency of manifestations of erosions and ulcers in gastroduodenal mucosa. Identification of these complications on the early stages may lead to more effective management of acute erosions and ulcers.
authors.forename: F I
authors.initials: FI
authors.lastname: Alyev
mesh_terms: D000070642:Brain Injuries, Traumatic / Q000150:complications / Q000503:physiopathology*; D018450:Disease Progression; D004703:Endocrine System / Q000503:physiopathology; D019723:Endoscopes; D005260:Female; D005753:Gastric Mucosa / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008833:Microcirculation / Q000502:physiology; D010437:Peptic Ulcer / Q000150:complications / Q000503:physiopathology*