title: Hidradenitis suppurativa: haploinsufficiency of gamma-secretase components does not affect gamma-secretase enzyme activity in vitro.
authors.affiliation: Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, U.K.
authors.forename: A E
authors.initials: AE
authors.lastname: Pink
authors.affiliation: Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, U.K.
authors.forename: D
authors.initials: D
authors.lastname: Dafou
authors.affiliation: St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust, London, U.K.
authors.forename: N
authors.initials: N
authors.lastname: Desai
authors.affiliation: Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, 02115, U.S.A.
authors.forename: O
authors.initials: O
authors.lastname: Holmes
authors.affiliation: The Wolffson Centre for Age Related Diseases, King's College London, London, U.K.
authors.forename: C
authors.initials: C
authors.lastname: Hobbs
authors.affiliation: Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, U.K.|St John's Institute of Dermatology, Guy's & St Thomas' NHS Foundation Trust, London, U.K.
authors.forename: C H
authors.initials: CH
authors.lastname: Smith
authors.affiliation: Division of Clinical Science, St George's University of London, London, U.K.
authors.forename: P
authors.initials: P
authors.lastname: Mortimer
authors.affiliation: Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, U.K.
authors.forename: M A
authors.initials: MA
authors.lastname: Simpson
authors.affiliation: Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, U.K.|Queen Mary University of London, Bart's and The London School of Medicine and Dentistry, London, U.K.
authors.forename: R C
authors.initials: RC
authors.lastname: Trembath
authors.affiliation: Division of Genetics and Molecular Medicine, King's College London School of Medicine, King's College London, London, U.K. Jonathan.barker@kcl.ac.uk.
authors.forename: J N
authors.initials: JN
authors.lastname: Barker
mesh_terms: D053829:Amyloid Precursor Protein Secretases / Q000235:genetics* / Q000378:metabolism; D001050:Apocrine Glands / Q000737:chemistry; D004817:Epidermis / Q000737:chemistry; D018859:Hair Follicle / Q000737:chemistry; D057895:Haploinsufficiency / Q000235:genetics*; D017497:Hidradenitis Suppurativa / Q000201:enzymology* / Q000235:genetics; D006801:Humans; D066298:In Vitro Techniques; D008562:Membrane Glycoproteins / Q000378:metabolism; D008565:Membrane Proteins / Q000378:metabolism; D009154:Mutation / Q000235:genetics*; D012627:Sebaceous Glands / Q000737:chemistry
chemical_list: D008562:Membrane Glycoproteins; D008565:Membrane Proteins; C469349:PSENEN protein, human; C413604:nicastrin protein; D053829:Amyloid Precursor Protein Secretases