title: Acute stroke therapy: A review.
abstract: This review summarizes the modern early diagnosis and acute phase treatment of acute stroke. The guidelines for treatment of acute ischemic stroke underwent major changes in 2015 and endovascular therapy (catheter-based mechanical thrombectomy with a stent retriever) became the class IA indication for patients presenting within less than 6h from symptom onset who have proven occlusion of large intracerebral artery in anterior circulation. Acute stroke care organization should enable to perform effective revascularization therapy as soon as possible after the initial brain imaging whenever this examination provides indication for the procedure.
authors.affiliation: Faculty Hospital Kralovske Vinohrady, Srobarova 50, Prague, Czech Republic. Electronic address: peisker@fnkv.cz.
authors.forename: Tomas
authors.initials: T
authors.lastname: Peisker
authors.affiliation: Faculty Hospital Kralovske Vinohrady, Srobarova 50, Prague, Czech Republic.
authors.forename: Boris
authors.initials: B
authors.lastname: Koznar
authors.affiliation: Faculty Hospital Kralovske Vinohrady, Srobarova 50, Prague, Czech Republic.
authors.forename: Ivana
authors.initials: I
authors.lastname: Stetkarova
authors.affiliation: Faculty Hospital Kralovske Vinohrady, Srobarova 50, Prague, Czech Republic.
authors.forename: Petr
authors.initials: P
authors.lastname: Widimsky
mesh_terms: D002533:Cerebral Angiography / Q000379:methods; D002548:Cerebral Revascularization / Q000009:adverse effects / Q000295:instrumentation / Q000379:methods*; D002560:Cerebrovascular Circulation; D000072226:Computed Tomography Angiography; D057510:Endovascular Procedures / Q000009:adverse effects / Q000295:instrumentation; D006801:Humans; D011237:Predictive Value of Tests; D012307:Risk Factors; D015607:Stents; D020521:Stroke / Q000000981:diagnostic imaging / Q000401:mortality / Q000503:physiopathology / Q000628:therapy*; D017131:Thrombectomy / Q000009:adverse effects; D015912:Thrombolytic Therapy / Q000009:adverse effects; D013997:Time Factors; D016896:Treatment Outcome
keywords: Acute stroke; Intravenous thrombolysis; Mechanical thrombectomy; Stent retriever