title: Value-based integrated (renal) care: setting a development agenda for research and implementation strategies.
abstract: Integrated care services are considered a vital strategy for improving the Triple Aim values for people with chronic kidney disease. However, a solid scholarly explanation of how to develop, implement and evaluate such value-based integrated renal care services is limited. The aim of this study was to develop a framework to identify the strategies and outcomes for the implementation of value-based integrated renal care.
  
  
  
  First, the theoretical foundations of the Rainbow Model of Integrated Care and the Triple Aim were united into one overarching framework through an iterative process of key-informant consultations. Second, a rapid review approach was conducted to identify the published research on integrated renal care, and the Cochrane Library, Medline, Scopus, and Business Source Premier databases were searched for pertinent articles published between 2000 and 2015. Based on the framework, a coding schema was developed to synthesis the included articles.
  
  
  
  The overarching framework distinguishes the integrated care domains: 1) type of integration, 2) enablers of integration and the interrelated outcome domains, 3) experience of care, 4) population health and 5) costs. The literature synthesis indicated that integrated renal care implementation strategies have particularly focused on micro clinical processes and physical outcomes, while little emphasis has been placed on meso organisational as well as macro system integration processes. In addition, evidence regarding patients' perceived outcomes and economic outcomes has been weak.
  
  
  
  These results underscore that the future challenge for researchers is to explore which integrated care implementation strategies achieve better health and improved experience of care at a lower cost within a specific context. For this purpose, this study's framework and evidence synthesis have set a developmental agenda for both integrated renal care practice and research. Accordingly, we plan further work to develop an implementation model for value-based integrated renal services.
authors.affiliation: Department of Health Services Research, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands. valentijn@essenburgh.nl.|Department Integrated Care University, Essenburgh, Hierden, The Netherlands. valentijn@essenburgh.nl.
authors.forename: Pim P
authors.initials: PP
authors.lastname: Valentijn
authors.affiliation: Faculty of Social Science, Ruhr University Bochum, Bochum, Germany.
authors.forename: Claus
authors.initials: C
authors.lastname: Biermann
authors.affiliation: Jan van Es Institute, Netherlands Expert Centre Integrated Primary Care, Almere, The Netherlands.
authors.forename: Marc A
authors.initials: MA
authors.lastname: Bruijnzeels
mesh_terms: D035843:Biomedical Research; D019033:Delivery of Health Care, Integrated; D006801:Humans; D010346:Patient Care Management / Q000458:organization & administration*; D051436:Renal Insufficiency, Chronic / Q000628:therapy*
keywords: Chronic kidney disease; Coordination of care; Delivery of care; Economics; Integrated care; Nephrology; Organization models; Quality improvement; Renal disease; Review