title: Timed Up and Go test: Comparison of kinematics between patients with chronic stroke and healthy subjects.
abstract: Understanding locomotor behavior is important to guide rehabilitation after stroke. This study compared lower-limb kinematics during the walking and turning sub-tasks of the Timed Up and Go (TUG) test in stroke patients and healthy subjects. We also determined the parameters which explain TUG sub-task performance time in healthy subjects. Biomechanical parameters were recorded during the TUG in standardized conditions in 25 healthy individuals and 29 patients with chronic stroke using a 3D motion-analysis system. Parameters were compared between groups and a stepwise regression was used to indicate parameters which explained performance time in the healthy subjects. The percentage difference in step length between the last and first steps was calculated, during walking sub-tasks for each group. Speed, cadence, step length, percentage paretic single support phase, percentage non-paretic swing phase, peak hip extension, knee flexion and ankle dorsiflexion were significantly reduced in the Stroke group compared to the Healthy group (p<0.05). In the Healthy group, step length and cadence explained 91% of variance for Go and 86% for Return (walking sub-tasks), and none of the parameters explained the Turn. Previous study in patients with stroke showed that the same parameters explained the variance during the walking sub-tasks and balance-related parameters explained the Turn. The present results showed that step length was differently modulated in each group. Thus the locomotor behavior of patients with stroke during obstacle circumvention is quite specific in light of the results obtained in healthy subjects.
authors.affiliation: Inserm Unit 1179, Team 3: Technologies and Innovative Therapies Applied to Neuromuscular Diseases, UVSQ, APHP Service de physiologie et d'exploration fonctionnelle, Hôpital Raymond Poincaré, 92380 Garches, France. Electronic address: celine.bonnyaud@rpc.aphp.fr.
authors.forename: Céline
authors.initials: C
authors.lastname: Bonnyaud
authors.affiliation: Inserm Unit 1179, Team 3: Technologies and Innovative Therapies Applied to Neuromuscular Diseases, UVSQ, APHP Service de physiologie et d'exploration fonctionnelle, Hôpital Raymond Poincaré, 92380 Garches, France.
authors.forename: Didier
authors.initials: D
authors.lastname: Pradon
authors.affiliation: Inserm CIC 1429, Hôpital R. Poincaré, AP-HP, Garches, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Vaugier
authors.affiliation: Univ. Grenoble Alpes Laboratoire AGIM, La Tronche, France; Institut Universitaire de France, Paris, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Vuillerme
authors.affiliation: Inserm Unit 1179, Team 3: Technologies and Innovative Therapies Applied to Neuromuscular Diseases, UVSQ, APHP Service de Médecine Physique et Réadaptation, Hôpital R. Poincaré, AP-HP, Garches, France.
authors.forename: Djamel
authors.initials: D
authors.lastname: Bensmail
authors.affiliation: Inserm Unit 1179, Team 3: Technologies and Innovative Therapies Applied to Neuromuscular Diseases, UVSQ, APHP Service de physiologie et d'exploration fonctionnelle, Hôpital Raymond Poincaré, 92380 Garches, France.
authors.forename: Nicolas
authors.initials: N
authors.lastname: Roche
mesh_terms: D000328:Adult; D000368:Aged; D001696:Biomechanical Phenomena; D002908:Chronic Disease; D005080:Exercise Test / Q000379:methods*; D005260:Female; D005684:Gait / Q000502:physiology*; D006801:Humans; D035002:Lower Extremity / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D009043:Motor Activity / Q000502:physiology*; D012016:Reference Values; D020521:Stroke / Q000503:physiopathology*; D013647:Task Performance and Analysis; D013997:Time Factors
keywords: Assessment; Hemiparesis; Motor control; Oriented-gait; Performance