title: Conducting and interpreting high-quality systematic reviews and meta-analyses.
abstract: Systematic reviews and meta-analyses are powerful tools for summarizing existing literature and combining evidence from multiple studies. These methods employ complex searches, statistical techniques, and presentation techniques with which the clinical audience may not be very familiar. This review article aims to familiarize the clinical audience with the various techniques employed to conduct a high-quality systematic review and meta-analysis.
authors.affiliation: Department of Medicine, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Rajat
authors.initials: R
authors.lastname: Kalra
authors.affiliation: Division of Cardiovascular Disease, University of Alabama at Birmingham, BDB D-201, 1808 7th Avenue South, Birmingham, AL, 35294-0012, USA.|Section of Cardiology, Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA.
authors.forename: Pankaj
authors.initials: P
authors.lastname: Arora
authors.affiliation: Department of Biostatistics, University of Alabama at Birmingham, Birmingham, AL, USA.
authors.forename: Charity
authors.initials: C
authors.lastname: Morgan
authors.affiliation: Division of Cardiovascular Disease, University of Alabama at Birmingham, BDB D-201, 1808 7th Avenue South, Birmingham, AL, 35294-0012, USA.|Section of Cardiology, Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA.
authors.forename: Fadi G
authors.initials: FG
authors.lastname: Hage
authors.affiliation: Division of Cardiovascular Disease, University of Alabama at Birmingham, BDB D-201, 1808 7th Avenue South, Birmingham, AL, 35294-0012, USA.
authors.forename: Ami E
authors.initials: AE
authors.lastname: Iskandrian
authors.affiliation: Division of Cardiovascular Disease, University of Alabama at Birmingham, BDB D-201, 1808 7th Avenue South, Birmingham, AL, 35294-0012, USA. nbajaj@uabmc.edu.|Section of Cardiology, Birmingham Veterans Affairs Medical Center, Birmingham, AL, USA. nbajaj@uabmc.edu.
authors.forename: Navkaranbir S
authors.initials: NS
authors.lastname: Bajaj
mesh_terms: D019317:Evidence-Based Medicine / Q000592:standards*; D017408:Guidelines as Topic; D038622:Internationality; D015201:Meta-Analysis as Topic; D011786:Quality Control; D012196:Review Literature as Topic
keywords: Systematic review; meta-analysis; network meta-analysis