title: Deep-Red and Near-Infrared Xanthene Dyes for Rapid Live Cell Imaging.
abstract: In this work, two xanthene dyes (H-hNR and TF-hNR) have been synthesized by a convenient and efficient method. These two dyes exhibited deep-red and near-infrared emissions, high fluorescence quantum yields, and good photostability. Their structure-optical properties were investigated by X-ray crystal structure analysis and density functional theory calculations. Live cell imaging data revealed that H-hNR and TF-hNR could rapidly stain both A549 and HeLa cells with low concentrations. The excellent photophysical and imaging properties render them as promising candidates for use in live cell imaging.
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.|University of Chinese Academy of Sciences , Beijing 100049, China.
authors.forename: Guangle
authors.initials: G
authors.lastname: Niu
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Weimin
authors.initials: W
authors.lastname: Liu
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Bingjiang
authors.initials: B
authors.lastname: Zhou
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Xiao
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Hongyan
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Jiasheng
authors.initials: J
authors.lastname: Wu
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Jiechao
authors.initials: J
authors.lastname: Ge
authors.affiliation: Key Laboratory of Photochemical Conversion and Optoelectronic Materials and CityU-CAS Joint Laboratory of Functional Materials and Devices, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Beijing 100190, China.
authors.forename: Pengfei
authors.initials: P
authors.lastname: Wang
mesh_terms: D000072283:A549 Cells; D018360:Crystallography, X-Ray; D005456:Fluorescent Dyes / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D007259:Infrared Rays; D009682:Magnetic Resonance Spectroscopy / Q000379:methods; D013058:Mass Spectrometry; D013050:Spectrometry, Fluorescence; D019265:Spectroscopy, Near-Infrared; D014966:Xanthenes / Q000032:analysis* / Q000378:metabolism / Q000494:pharmacology
chemical_list: D005456:Fluorescent Dyes; D014966:Xanthenes