title: Biophysical and chemical handles to control the size of DNA nanoparticles produced by rolling circle amplification.
abstract: Although rolling circle amplification (RCA) is an efficient method to produce DNA materials for biomedical applications, it does not yield nano-sized products suitable for intracellular delivery. We here provide the ways to control the size of RCA products and show a potential application of the size-controlled DNA nanoparticles.
authors.affiliation: The Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. drahn@kist.re.kr and Department of Chemistry, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, Republic of Korea.
authors.forename: So Yeon
authors.initials: SY
authors.lastname: Lee
authors.affiliation: The Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. drahn@kist.re.kr and Department of Chemistry, College of Science, Yonsei University, Seoul, Republic of Korea.
authors.forename: Kyoung-Ran
authors.initials: KR
authors.lastname: Kim
authors.affiliation: Department of Chemistry, College of Science, Yonsei University, Seoul, Republic of Korea.
authors.forename: Duhee
authors.initials: D
authors.lastname: Bang
authors.affiliation: Green Materials and Process Group, Korea Institute of Industrial Technology, Cheonan, Chungnam 31056, Republic of Korea.
authors.forename: Se Won
authors.initials: SW
authors.lastname: Bae
authors.affiliation: Department of Chemistry, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul, Republic of Korea.
authors.forename: Hak Joong
authors.initials: HJ
authors.lastname: Kim
authors.affiliation: The Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology (KIST), Hwarangno 14-gil 5, Seongbuk-gu, Seoul 136-791, Republic of Korea. drahn@kist.re.kr and Department of Biological Chemistry, KIST campus, University of Science and Technology (UST), Republic of Korea.
authors.forename: Dae-Ro
authors.initials: DR
authors.lastname: Ahn
mesh_terms: D001703:Biophysics; D004247:DNA / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry*; D021141:Nucleic Acid Amplification Techniques; D010316:Particle Size
chemical_list: D004247:DNA