title: Comment on "Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice".
abstract: In Apc(Min) mice (an animal model of colorectal carcinogenesis) fed a high-fat diet, low doses of resveratrol suppress intestinal adenoma development more potently than high doses do; however, these findings appear affected by multiple confounding factors, as resveratrol alone added to a standard diet has opposite outcomes.
authors.affiliation: Unit of Cancer Pathology, CeSI-MeT, University "G. d'Annunzio," 66100 Chieti, Italy.
authors.forename: Emanuela
authors.initials: E
authors.lastname: Guerra
authors.affiliation: Unit of Cancer Pathology, CeSI-MeT, University "G. d'Annunzio," 66100 Chieti, Italy. Department of Medical, Oral, and Biotechnological Sciences, University "G. d'Annunzio," 66100 Chieti, Italy.
authors.forename: Mauro
authors.initials: M
authors.lastname: Piantelli
authors.affiliation: Unit of Cancer Pathology, CeSI-MeT, University "G. d'Annunzio," 66100 Chieti, Italy. Department of Neuroscience, Imaging, and Clinical Sciences, Unit of Physiology and Physiopathology, University "G. d'Annunzio," 66100 Chieti, Italy. s.alberti@unich.it.
authors.forename: Saverio
authors.initials: S
authors.lastname: Alberti
mesh_terms: D000236:Adenoma; D000818:Animals; D018890:Chemoprevention; D059305:Diet, High-Fat; D006801:Humans; D051379:Mice; D008810:Mice, Inbred C57BL; D000077185:Resveratrol; D013267:Stilbenes
chemical_list: D013267:Stilbenes; D000077185:Resveratrol