title: Remarkable In Vivo Nonlinear Photoacoustic Imaging Based on Near-Infrared Organic Dyes.
abstract: Two near-infrared dyes featuring good dispersion and light-harvesting property present a remarkable nonlinear photoacoustic response in vitro and in vivo comparing with conventional gold nanorods. This study benefits the fabrication of drug delivery platforms with accurate targeting and control effect under photoacoustic image guidance.
authors.affiliation: School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798.
authors.forename: Fei
authors.initials: F
authors.lastname: Gao
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371.
authors.forename: Linyi
authors.initials: L
authors.lastname: Bai
authors.affiliation: School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798.
authors.forename: Xiaohua
authors.initials: X
authors.lastname: Feng
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371.
authors.forename: Huijun Phoebe
authors.initials: HP
authors.lastname: Tham
authors.affiliation: School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798.
authors.forename: Ruochong
authors.initials: R
authors.lastname: Zhang
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371.
authors.forename: Yuanyuan
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798.
authors.forename: Siyu
authors.initials: S
authors.lastname: Liu
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371.
authors.forename: Lingzhi
authors.initials: L
authors.lastname: Zhao
authors.affiliation: School of Electrical and Electronic Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798. yjzheng@ntu.edu.sg.
authors.forename: Yuanjin
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: Division of Chemistry and Biological Chemistry, School of Physical and Mathematical Sciences, Nanyang Technological University, 21 Nanyang Link, Singapore, 637371. zhaoyanli@ntu.edu.sg.|School of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore, 639798. zhaoyanli@ntu.edu.sg.
authors.forename: Yanli
authors.initials: Y
authors.lastname: Zhao
mesh_terms: D000818:Animals; D001565:Benzoates / Q000737:chemistry; D005456:Fluorescent Dyes / Q000737:chemistry*; D021621:Imaging, Three-Dimensional; D007208:Indocyanine Green / Q000031:analogs & derivatives / Q000737:chemistry; D007211:Indoles / Q000737:chemistry; D007259:Infrared Rays; D043942:Nanotubes / Q000737:chemistry / Q000648:ultrastructure; D017711:Nonlinear Dynamics; D009930:Organic Chemicals / Q000737:chemistry*; D061088:Photoacoustic Techniques / Q000379:methods*; D051381:Rats
chemical_list: D001565:Benzoates; D005456:Fluorescent Dyes; C541053:IR 820; C000601126:IR825 dye; D007211:Indoles; D009930:Organic Chemicals; D007208:Indocyanine Green
keywords: bioimaging; in vivo studies; near-infrared dyes; nonlinear response; photoacoustic tomography