title: Optical coherence tomography impacts the evaluation of visual pathway tumors.
abstract: The objective of this systematic literature review is to assess the role of retinal optical coherence tomography (OCT) in the evaluation of patients with tumors of the visual pathway. We performed a PubMed database search according to the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. The search was restricted to articles published in English between 2000 and 2016, with at least 10 human adult participants enrolled. Twenty-seven articles met the eligibility criteria. All studies investigated tumors of the anterior visual pathway. Both time-domain and spectral-domain OCT technologies were used and the role of OCT as diagnostic and/or prognostic tool was studied. Retinal OCT provides structural information about ganglion cell axon integrity and is complementary to visual function examination. OCT is a prognostic factor for post-operative visual outcome.
authors.affiliation: Department of Ophthalmology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Clinicilor Street no 3-5, 400006, Cluj-Napoca, Romania. Ana.Banc@umfcluj.ro.|Clinic of Ophthalmology, Emergency County Hospital Cluj, Cluj-Napoca, Romania. Ana.Banc@umfcluj.ro.
authors.forename: Ana
authors.identifier: http://orcid.org/0000-0003-2157-7741
authors.initials: A
authors.lastname: Banc
authors.affiliation: Department of Ophthalmology, "Iuliu Hatieganu" University of Medicine and Pharmacy, Clinicilor Street no 3-5, 400006, Cluj-Napoca, Romania.|Clinic of Ophthalmology, Emergency County Hospital Cluj, Cluj-Napoca, Romania.
authors.forename: Cristina
authors.initials: C
authors.lastname: Stan
authors.affiliation: Department of Neurosurgery, "Iuliu Hatieganu" University of Medicine and Pharmacy, Cluj-Napoca, Romania.|Clinic of Neurosurgery, Emergency County Hospital Cluj, Cluj-Napoca, Romania.
authors.forename: Ioan Stefan
authors.initials: IS
authors.lastname: Florian
mesh_terms: D006801:Humans; D009408:Nerve Compression Syndromes / Q000000981:diagnostic imaging* / Q000601:surgery; D009778:Occipital Lobe / Q000000981:diagnostic imaging; D009897:Optic Chiasm / Q000000981:diagnostic imaging*; D019574:Optic Nerve Neoplasms / Q000000981:diagnostic imaging* / Q000601:surgery; D011183:Postoperative Complications / Q000209:etiology; D012160:Retina / Q000000981:diagnostic imaging; D012165:Retinal Ganglion Cells; D041623:Tomography, Optical Coherence; D014793:Visual Cortex / Q000000981:diagnostic imaging; D014795:Visual Pathways / Q000000981:diagnostic imaging* / Q000601:surgery
keywords: Optical coherence tomography; Retinal nerve fiber layer; Tumor; Visual pathway