title: Vision-related Quality of Life in Glaucoma Suspect or Early Glaucoma Patients.
abstract: To determine the association of vision-related quality of life (QoL) to demographic factors and visual function in glaucoma suspect or early glaucoma patients.
  
  
  
  We administered the 25-item National Eye Institute Visual Function Questionnaire (VFQ-25) on the same day as a comprehensive ocular examination to participants either with glaucoma or at high risk for developing glaucoma. Regression models were used to determine the association between VFQ-25 composite and subscale scores, visual field status, logMAR equivalent visual acuity (VA), age, and sex. In all analyses we used data from the eye with the best mean deviation (MD), best pattern SD, and best VA.
  
  
  
  Data from 198 participants were analyzed. The mean best MD (±SD) was 0.02±1.52 dB (range, -5.11 to 2.63 dB) and the mean best pattern SD was 1.75±1.03 dB (range, 0.91 to 8.36 dB). The mean VFQ-25 composite score was 91.6±6.7 (range, 54.5 to 100.0). Composite score and the Distance Activities, Color Vision subscale scores were associated with best MD (P≤0.05). The General Vision and Driving subscale scores were associated with best VA (P≤0.03). The composite score and the Distance Activities, Driving, and Color Vision subscale scores were associated with age (P≤0.05). Finally, the Distance Activities, Driving, and Peripheral Vision subscale scores were associated with sex (P≤0.04).
  
  
  
  Vision-related QoL is associated with visual field status even in early and suspected glaucoma. It is also associated with VA, age, and sex. Particular decreases in QoL are related to distance activities, driving, and color vision.
authors.affiliation: Devers Eye Institute, Legacy Health, Portland, OR.
authors.forename: Asem
authors.initials: A
authors.lastname: Alqudah
authors.forename: Steven L
authors.initials: SL
authors.lastname: Mansberger
authors.forename: Stuart K
authors.initials: SK
authors.lastname: Gardiner
authors.forename: Shaban
authors.initials: S
authors.lastname: Demirel
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D003430:Cross-Sectional Studies; D005260:Female; D005901:Glaucoma / Q000150:complications / Q000503:physiopathology / Q000523:psychology; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D008297:Male; D008875:Middle Aged; D054554:National Eye Institute (U.S.); D011788:Quality of Life; D018434:Sickness Impact Profile; D011795:Surveys and Questionnaires; D014481:United States; D014786:Vision Disorders / Q000209:etiology / Q000503:physiopathology / Q000523:psychology; D014792:Visual Acuity / Q000502:physiology; D014794:Visual Fields / Q000502:physiology