title: [Effects of Gelatin on Performance of α-tricalcium Phosphate Bone Cement].
abstract: OBJECTIVE
  To determine the effects of gelatin on the performance of calcium phosphate cement (CPC).
  
  
  METHODS
  α-tricalcium phosphate (α-TCP) bone cement was mixed with different concentrations of gelatin solutions. The CPC samples were soaked into simulated body fluid for one day before their compressive and bending strengths were measured. We also compared their waterproof performance, solidification time and surface topography.
  
  
  RESULTS
  Gelatin solutions changed the performance of CPC. Optimal performance of CPC was achieved when the volume ratio of gelatin solution to CPC (Vgelatin solution:V(CPC liquid)) was set at 25:100, which increased compressive strength from (7.874 54 ± 0.660 97) MPa to (9.936 52 ± 0.433 17) MPa and bending strength from (5.157 06 ± 0.298 30) MPa to (7.959 71 ± 0.281 63) MPa. Gelatin solution also prolonged setting time of CPC, improved its waterproof performance, and promoted formulation of more dense and uniform hydroxyapatite crystals.
  
  
  CONCLUSIONS
  Gelatin can improve the compressive and bending strengths of CPC, and make CPC more suitable for clinic use through improvements in setting time and waterproof performance.
authors.forename: Li-juan
authors.initials: LJ
authors.lastname: Xiao
authors.forename: Zheng
authors.initials: Z
authors.lastname: Yang
authors.forename: Yi
authors.initials: Y
authors.lastname: Man
authors.forename: Liang
authors.initials: L
authors.lastname: Hao
authors.forename: Min
authors.initials: M
authors.lastname: Wang
authors.forename: Guang-da
authors.initials: GD
authors.lastname: Li
authors.forename: Hao
authors.initials: H
authors.lastname: Liu
mesh_terms: D001843:Bone Cements / Q000737:chemistry*; D002130:Calcium Phosphates / Q000737:chemistry*; D019245:Compressive Strength; D005780:Gelatin / Q000737:chemistry*; D008422:Materials Testing
chemical_list: D001843:Bone Cements; D002130:Calcium Phosphates; C485828:alpha-tricalcium phosphate; D005780:Gelatin