title: PvTFDB: a Phaseolus vulgaris transcription factors database for expediting functional genomics in legumes.
abstract: The common bean [Phaseolus vulgaris (L.)] is one of the essential proteinaceous vegetables grown in developing countries. However, its production is challenged by low yields caused by numerous biotic and abiotic stress conditions. Regulatory transcription factors (TFs) symbolize a key component of the genome and are the most significant targets for producing stress tolerant crop and hence functional genomic studies of these TFs are important. Therefore, here we have constructed a web-accessible TFs database for P. vulgaris, called PvTFDB, which contains 2370 putative TF gene models in 49 TF families. This database provides a comprehensive information for each of the identified TF that includes sequence data, functional annotation, SSRs with their primer sets, protein physical properties, chromosomal location, phylogeny, tissue-specific gene expression data, orthologues, cis-regulatory elements and gene ontology (GO) assignment. Altogether, this information would be used in expediting the functional genomic studies of a specific TF(s) of interest. The objectives of this database are to understand functional genomics study of common bean TFs and recognize the regulatory mechanisms underlying various stress responses to ease breeding strategy for variety production through a couple of search interfaces including gene ID, functional annotation and browsing interfaces including by family and by chromosome. This database will also serve as a promising central repository for researchers as well as breeders who are working towards crop improvement of legume crops. In addition, this database provide the user unrestricted public access and the user can download entire data present in the database freely.Database URL: http://www.multiomics.in/PvTFDB/.
authors.affiliation: Institute of Biotechnology, PJTSAU, Rajendra Nagar, Hyderabad 500030, India.
authors.lastname: Bhawna
authors.affiliation: Institute of Biotechnology, PJTSAU, Rajendra Nagar, Hyderabad 500030, India.
authors.forename: V S
authors.initials: VS
authors.lastname: Bonthala
authors.affiliation: Institute of Biotechnology, PJTSAU, Rajendra Nagar, Hyderabad 500030, India gajula.ibt@gmail.com.
authors.forename: Mnv Prasad
authors.initials: MP
authors.lastname: Gajula
mesh_terms: D030561:Databases, Nucleic Acid; D030562:Databases, Protein; D017343:Genes, Plant / Q000502:physiology*; D027805:Phaseolus / Q000235:genetics / Q000378:metabolism; D010940:Plant Proteins / Q000235:genetics / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics / Q000378:metabolism
chemical_list: D010940:Plant Proteins; D014157:Transcription Factors