title: Z-Selective Synthesis of γ,δ-Unsaturated Ketones via Pd-Catalyzed Ring Opening of 2-Alkylenecyclobutanones with Arylboronic Acids.
abstract: Pd-catalyzed 1,2-addition (instead of 1,4-addition) of arylboronic acids to 2-alkylenecyclobutanones followed by β-carbon elimination from the resulting palladium cyclobutanolates to afford γ,δ-unsaturated ketones was developed. The desired γ,δ-unsaturated ketones were obtained in good to excellent yields with Z/E selectivities of up to >99:1 and a broad spectrum of functional group tolerability.
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering at Huaqiao University , 668 Jimei Boulevard, Xiamen, Fujian 361021, P. R. China.
authors.forename: Yao
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering at Huaqiao University , 668 Jimei Boulevard, Xiamen, Fujian 361021, P. R. China.
authors.forename: Changqing
authors.initials: C
authors.lastname: Rao
authors.affiliation: Institute of Next Generation Matter Transformation, College of Chemical Engineering, College of Materials Science & Engineering at Huaqiao University , 668 Jimei Boulevard, Xiamen, Fujian 361021, P. R. China.|National Laboratory for Molecular Sciences, Institute of Chemistry , Beijing 100190, P. R. China.
authors.forename: Qiuling
authors.initials: Q
authors.lastname: Song