title: High incidence of group A rotaviruses G4P[6] strains among children in Gyeonggi province of South Korea, from 2009 to 2012.
abstract: The genotype distribution of group A rotaviruses (RVAs) circulating in Gyeonggi province, South Korea between 2009 and 2012 was investigated. A total of 2619 stool specimens from sporadic acute gastroenteritis cases and 117 acute gastroenteritis outbreaks were analyzed. Among them, RVAs were detected from 263 (10.0%) sporadic cases and 3 (2.6%) outbreaks. The G4P[6] strains predominated (29.7%), followed by G1P[8] (19.4%), G2P[4] (15.6%), G3P[8] (13.3%) and G9P[8] (6.5%) strain. Especially 96.2% of the genotype G4P[6] strains were isolated from children<1year of age. Phylogenetic analysis revealed that genotype G4P[6] strains were members of sub-lineage Ie(G4) and Ia(P[6]). Intensified monitoring of RVAs, especially G4P[6] strains among young children, is essential to control RVA infections.
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, South Korea.
authors.forename: Su-Kyoung
authors.initials: SK
authors.lastname: Mun
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, South Korea.
authors.forename: Han-Gil
authors.initials: HG
authors.lastname: Cho
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, South Korea.
authors.forename: Hyun-Kyung
authors.initials: HK
authors.lastname: Lee
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, South Korea.
authors.forename: Sin-Hee
authors.initials: SH
authors.lastname: Park
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, South Korea.
authors.forename: Po-Hyun
authors.initials: PH
authors.lastname: Park
authors.affiliation: Division of Public Health Research, Gyeonggi Province Institute of Health and Environment, Suwon, South Korea.
authors.forename: Mi-Hye
authors.initials: MH
authors.lastname: Yoon
authors.affiliation: Division of Vaccine Research, Center for Infectious Diseases, National Institute of Health, Korea Centers for Disease Control & Prevention, Chungcheongbuk-do, South Korea.
authors.forename: Hye-Sook
authors.initials: HS
authors.lastname: Jeong
authors.affiliation: Department of Public Health Science, Graduate School, Korea University, Seoul, South Korea; Department of Laboratory Medicine, Korea University Guro Hospital, Seoul, South Korea. Electronic address: yhlim@korea.ac.kr.
authors.forename: Young-Hee
authors.initials: YH
authors.lastname: Lim
mesh_terms: D036022:Capsid Proteins / Q000235:genetics; D002675:Child, Preschool; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000821:virology; D005838:Genotype; D049674:History, 21st Century; D006801:Humans; D015994:Incidence; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D017720:Molecular Epidemiology; D010802:Phylogeny; D062486:Public Health Surveillance; D012367:RNA, Viral; D056910:Republic of Korea / Q000453:epidemiology; D012401:Rotavirus / Q000145:classification* / Q000235:genetics*; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000266:history / Q000821:virology*; D017422:Sequence Analysis, DNA
chemical_list: D036022:Capsid Proteins; D012367:RNA, Viral
keywords: Acute gastroenteritis; Children; Genotype; Group A rotavirus