title: Paediatric intraocular lens implants: accuracy of lens power calculations.
abstract: PurposeThis study aims to evaluate the accuracy of lens prediction formulae on a paediatric population.MethodsA retrospective case-note review was undertaken of patients under 8 years old who underwent cataract surgery with primary lens implantation in a regional referral centre for paediatric ophthalmology, excluding those whose procedure was secondary to trauma. Biometric and refractive data were analysed for 43 eyes, including prediction errors (PE). Statistical measures used included mean absolute error (MAE), median absolute error (MedAE), Student's t-test and Lin's correlation coefficient.ResultsThe mean PE using the SRK-II formula was +0.96 D (range -2.47D to +2.41 D, SD 1.33 D, MAE 1.38 D, MedAE 1.55, n=15). The mean PE was smaller using SRK/T (-0.18 D, range -3.25 D to +3.95 D, SD 1.70 D, MAE 1.30 D, MedAE 1.24, n=27). We performed an analysis of the biometry data using four different formula (Hoffer Q, Holladay 1, SRK-II and SRK/T). Hoffer Q showed a smaller MedAE than other formulae but also a myopic bias.ConclusionOur clinical data suggest SRK/T was more accurate in predicting post-operative refraction in this cohort of paediatric patients undergoing cataract surgery. Hoffer Q may have improved accuracy further.
authors.affiliation: Department of Ophthalmology, Eye and Ear Clinic Royal Victoria Hospital, Belfast, UK.
authors.forename: M K
authors.initials: MK
authors.lastname: O'Gallagher
authors.affiliation: Department of Ophthalmology, Eye and Ear Clinic Royal Victoria Hospital, Belfast, UK.
authors.forename: M A
authors.initials: MA
authors.lastname: Lagan
authors.affiliation: Department of Ophthalmology, Eye and Ear Clinic Royal Victoria Hospital, Belfast, UK.
authors.forename: C P
authors.initials: CP
authors.lastname: Mulholland
authors.affiliation: Northern Ireland Clinical Research Support Centre, The Royal Hospitals, Belfast, UK.
authors.forename: M
authors.initials: M
authors.lastname: Parker
authors.affiliation: Department of Ophthalmology, Eye and Ear Clinic Royal Victoria Hospital, Belfast, UK.
authors.forename: G
authors.initials: G
authors.lastname: McGinnity
authors.affiliation: Department of Ophthalmology, Eye and Ear Clinic Royal Victoria Hospital, Belfast, UK.
authors.forename: E M
authors.initials: EM
authors.lastname: McLoone
mesh_terms: D058452:Axial Length, Eye / Q000473:pathology; D001699:Biometry / Q000379:methods*; D002387:Cataract Extraction; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D007223:Infant; D019654:Lens Implantation, Intraocular; D007910:Lenses, Intraocular; D008297:Male; D049451:Nomograms; D055095:Optics and Photonics; D012029:Refraction, Ocular / Q000502:physiology; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014792:Visual Acuity / Q000502:physiology