title: Copper-catalyzed intermolecular chloroazidation of α,β-unsaturated amides.
abstract: A highly practical copper-catalyzed intermolecular chloroazidation of α,β-unsaturated amides has been described, giving a series of azidochlorides in good-to-excellent yields. The stable azidoiodine(iii) reagent and SOCl2 were used as azide and chlorine sources, respectively. The synthetic applications of this protocol were also explored by a variety of synthetically useful transformations.
authors.affiliation: Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals and Wuhan University School of Pharmaceutical Sciences, Wuhan 430071, P. R. China. zxjiang@whu.edu.cn zgyang@whu.edu.cn.
authors.forename: Long
authors.initials: L
authors.lastname: Chen
authors.forename: Haotian
authors.initials: H
authors.lastname: Xing
authors.forename: Huaibin
authors.initials: H
authors.lastname: Zhang
authors.forename: Zhong-Xing
authors.initials: ZX
authors.lastname: Jiang
authors.forename: Zhigang
authors.initials: Z
authors.lastname: Yang