title: Salvage resection for recurrent or metastatic hepatocellular carcinoma after percutaneous ablation therapy.
abstract: BACKGROUND
  To retrospectively evaluate the efficacy and safety of salvage resection(SR) for recurrence or metastasis of hepatocellular carcinoma (HCC) after initial percutaneous ablation therapy (PAT).
  
  
  METHODS
  From September 2006 to September 2013, 50 consecutive patients who received SR for recurrent or metastatic HCC undergone initial PAT were enrolled. Safety and efficacy of SR for these patients were analyzed.
  
  
  RESULTS
  No treatment-related death occurred. Curative outcome was achieved in all the patients. The median overall survival after SR was 40 months, and the 1-, 3-, 5-year overall survival rate after SR was 85.2%, 46.4% and 34.8%, respectively. The disease-free survival was 38.6% at 1 year and 12.1% at 3 years after SR.
  
  
  CONCLUSIONS
  SR is an effective and safe method for patients with recurrent or metastatic HCC after initial PAT treatment.
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Wenjie
authors.initials: W
authors.lastname: Hu
authors.affiliation: Department of Oncology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Zhenwei
authors.initials: Z
authors.lastname: Peng
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Dongming
authors.initials: D
authors.lastname: Li
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Shunli
authors.initials: S
authors.lastname: Shen
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Jiali
authors.initials: J
authors.lastname: Li
authors.affiliation: Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
authors.forename: Shengnan
authors.initials: S
authors.lastname: Ruan
authors.affiliation: Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, 510080, China.
authors.forename: Mingfang
authors.initials: M
authors.lastname: Zhang
authors.affiliation: Department of Medical Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Baoxian
authors.initials: B
authors.lastname: Liu
authors.affiliation: Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Manxia
authors.initials: M
authors.lastname: Lin
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Shaoqiang
authors.initials: S
authors.lastname: Li
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Qiang
authors.initials: Q
authors.lastname: He
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Baogang
authors.initials: B
authors.lastname: Peng
authors.affiliation: Department of Medical Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Xiaoyan
authors.initials: X
authors.lastname: Xie
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China; Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China.
authors.forename: Mingde
authors.initials: M
authors.lastname: Lu
authors.affiliation: Department of Liver Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China; Division of Interventional Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, China. Electronic address: kuangminda@hotmail.com.
authors.forename: Ming
authors.initials: M
authors.lastname: Kuang
mesh_terms: D000328:Adult; D000368:Aged; D006528:Carcinoma, Hepatocellular / Q000401:mortality / Q000601:surgery*; D017115:Catheter Ablation / Q000009:adverse effects / Q000379:methods*; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000009:adverse effects / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000601:surgery; D012189:Retrospective Studies; D016879:Salvage Therapy / Q000009:adverse effects / Q000379:methods* / Q000401:mortality; D015996:Survival Rate; D016896:Treatment Outcome
keywords: Percutaneous ablation therapy; Recurrent or metastatic HCC; Salvage resection