title: Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and heart failure.
abstract: Obese individuals are more likely to develop heart failure. Yet, once heart failure is established, the impact of overweight and obesity on prognosis and survival is unclear. The purpose of this joint scientific statement of the European Association for the Study of Obesity and the European Society of Hypertension is to provide an overview on the current scientific literature on obesity and heart failure in terms of prognosis, mechanisms, and clinical management implications. Moreover, the document identifies open questions that ought to be addressed. The need for more tailored weight management recommendations in heart failure will be emphasized and, in line with the emerging evidence, aims to distinguish between primary disease and secondary outcome prevention. In the primary prevention of heart failure, it appears prudent advising obese individuals to lose or achieve a healthy body weight, especially in those with risk factors such as hypertension or type 2 diabetes. However, there is no evidence from clinical trials to guide weight management in overweight or obese patients with established heart failure. Prospective clinical trials are strongly encouraged.
authors.affiliation: aInstitute for Clinical Pharmacology, Medical School Hannover, Hannover, Germany bDepartment of Medicine, Medical University Graz, Graz, Austria cClinica Medica, Dipartimento di Medicina e Chirurgia, Universita Milano-Bicocca dIRCCS Multimedica, Milan, Italy eDepartment of Medicine, Division of Endocrinology and Metabolism, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey fHypertension-24h ABPM ESH Center of Excellence, Papageorgiou Hospital, Aristotle University Thessaloniki, Thessaloniki, Greece gIRCCS Istituto Auxologico, Milan, Italy hDepartment of Clinical Sciences, Lund University, University Hospital, Malmö, Sweden iNational Centre for Cardiovascular Prevention and Outcomes, UCL Institute of Cardiovascular Science, London, UK jCenter for Stroke Research Berlin (CSB) kDepartment of Cardiology, Virchow Campus, Charite Charité - Universitätsmedizin Berlin lPartner Site of the German Center for Cardiovascular Diseases (DZHK), Berlin, Germany *Nick Finer and Wolfram Doehner contributed equally to the manuscript.
authors.forename: Jens
authors.initials: J
authors.lastname: Jordan
authors.forename: Hermann
authors.initials: H
authors.lastname: Toplak
authors.forename: Guido
authors.initials: G
authors.lastname: Grassi
authors.forename: Volkan
authors.initials: V
authors.lastname: Yumuk
authors.forename: Vasilios
authors.initials: V
authors.lastname: Kotsis
authors.forename: Stefan
authors.initials: S
authors.lastname: Engeli
authors.forename: Cesare
authors.initials: C
authors.lastname: Cuspidi
authors.forename: Peter M
authors.initials: PM
authors.lastname: Nilsson
authors.forename: Nick
authors.initials: N
authors.lastname: Finer
authors.forename: Wolfram
authors.initials: W
authors.lastname: Doehner
mesh_terms: D005060:Europe; D006333:Heart Failure / Q000150:complications / Q000453:epidemiology; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology; D009765:Obesity / Q000150:complications / Q000453:epidemiology; D011379:Prognosis; D012307:Risk Factors; D012955:Societies, Medical