title: MR1 discovery.
abstract: The moment of MR1 discovery is described. The MR1 gene is the first and the last reported human MHC-related gene intentionally isolated from the human genome composed of three billion base pairs. Evolutionary considerations formed the basis of its isolation. Some details surrounding the moment and some retrospective descriptions with various kinds of encounters are also included.
authors.affiliation: Department of Biomedical Polymer Science, Institute for Comprehensive Medical Science, Fujita Health University, Toyoake, Aichi, 470-1192, Japan. keihashi@fujita-hu.ac.jp.
authors.forename: Keiichiro
authors.initials: K
authors.lastname: Hashimoto
mesh_terms: D019143:Evolution, Molecular; D005805:Genes, MHC Class I / Q000235:genetics*; D015894:Genome, Human; D015395:Histocompatibility Antigens Class I / Q000235:genetics* / Q000378:metabolism*; D006801:Humans; D015778:Minor Histocompatibility Antigens / Q000235:genetics* / Q000378:metabolism*
chemical_list: D015395:Histocompatibility Antigens Class I; C094840:MR1 protein, human; D015778:Minor Histocompatibility Antigens
keywords: MHC; MR1; PCR