title: Slow rhythms and sleep spindles in early infancy.
abstract: OBJECTIVE
  To investigate the slow rhythm and its relationship to spindling in early infancy.
  
  
  METHODS
  We analyzed sleep MEG recordings containing sleep spindles, taken from 7 normal, healthy subjects at conceptional age 46-63 weeks in 21 sessions.
  
  
  RESULTS
  We show that the sleep MEG in early infancy contains a slow rhythm, centered at approximately 0.2Hz, which showed a striking association with spindling. The slow rhythm grouped sleep spindles, which were clock-like with a recurrence rate of approximately 0.1Hz.
  
  
  CONCLUSIONS
  The association of the 0.2Hz oscillation and low delta rhythms with spindling was so strong as to suggest that they may play a critical role during brain development in the genesis of sleep spindles.
  
  
  CONCLUSIONS
  Infant brain rhythms exhibit relatively simple, regular behavior, allowing the relationships between them to be more easily discerned.
authors.affiliation: Dept. of Medical Physics University of Wisconsin-Madison, Madison, WI 53705-2275, USA. Electronic address: rtwakai@wisc.edu.
authors.forename: R T
authors.initials: RT
authors.lastname: Wakai
authors.affiliation: Dept. of Medical Physics University of Wisconsin-Madison, Madison, WI 53705-2275, USA.
authors.forename: W J
authors.initials: WJ
authors.lastname: Lutter
mesh_terms: D058256:Brain Waves; D002540:Cerebral Cortex / Q000502:physiology*; D003700:Delta Rhythm; D004569:Electroencephalography; D006801:Humans; D007223:Infant; D015225:Magnetoencephalography; D012890:Sleep
keywords: Magnetoencephalography; Sleep spindles; Slow rhythm