title: Nickel-Catalyzed Reductive Cross-Coupling of Aryl Bromides with Alkyl Bromides: Et3N as the Terminal Reductant.
abstract: Reductive cross-coupling has emerged as a direct method for the construction of carbon-carbon bonds. Most cobalt-, nickel-, and palladium-catalyzed reductive cross-coupling reactions to date are limited to stoichiometric Mn(0) or Zn(0) as the reductant. One nickel-catalyzed cross-coupling paradigm using Et3N as the terminal reductant is reported. By using this photoredox catalysis and nickel catalysis approach, a direct Csp(2)-Csp(3) reductive cross-coupling of aryl bromides with alkyl bromides is achieved under mild conditions without stoichiometric metal reductants.
authors.affiliation: College of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan University , Wuhan 430072, P. R. China.
authors.forename: Zhengli
authors.initials: Z
authors.lastname: Duan
authors.affiliation: College of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan University , Wuhan 430072, P. R. China.
authors.forename: Wu
authors.initials: W
authors.lastname: Li
authors.affiliation: College of Chemistry and Molecular Sciences, the Institute for Advanced Studies (IAS), Wuhan University , Wuhan 430072, P. R. China.
authors.forename: Aiwen
authors.initials: A
authors.lastname: Lei