title: Maternal Sleep Quality and Diurnal Cortisol Regulation Over Pregnancy.
abstract: Poor sleep in pregnancy is related to adverse neonatal health. Elevated maternal cortisol has been proposed as a pathway, yet the association in pregnancy is not well understood. The goals of the current study were to examine associations between (a) sleep and cortisol, (b) sleep, cortisol, and neonatal outcomes, and (c) variables that could explain these associations. Two hundred pregnant women completed the Pittsburgh Sleep Quality Index (PSQI; Buysse, Reynolds, Monk, Berman, & Kupfer, 1989) and provided diurnal salivary cortisol samples at two times over pregnancy. Poor sleep quality was associated with greater evening cortisol concentrations at 36 weeks' gestation. This association was mediated by anxiety symptoms. Higher evening cortisol at 36 weeks' gestation was associated with shorter gestation.
authors.affiliation: a Centers for Behavioral and Preventive Medicine , The Miriam Hospital , Providence , Rhode Island , USA.|b Department of Psychiatry and Human Behavior , Alpert Medical School of Brown University , Providence , Rhode Island , USA.
authors.forename: Margaret H
authors.initials: MH
authors.lastname: Bublitz
authors.affiliation: c Department of Medicine , The Miriam Hospital, Alpert Medical School of Brown University , Providence , Rhode Island , USA.
authors.forename: Ghada
authors.initials: G
authors.lastname: Bourjeily
authors.affiliation: a Centers for Behavioral and Preventive Medicine , The Miriam Hospital , Providence , Rhode Island , USA.
authors.forename: Christina
authors.initials: C
authors.lastname: D'Angelo
authors.affiliation: a Centers for Behavioral and Preventive Medicine , The Miriam Hospital , Providence , Rhode Island , USA.|b Department of Psychiatry and Human Behavior , Alpert Medical School of Brown University , Providence , Rhode Island , USA.
authors.forename: Laura R
authors.initials: LR
authors.lastname: Stroud
mesh_terms: D000293:Adolescent; D000328:Adult; D001007:Anxiety / Q000378:metabolism / Q000503:physiopathology; D002940:Circadian Rhythm / Q000502:physiology*; D005260:Female; D005865:Gestational Age; D006801:Humans; D006854:Hydrocortisone / Q000032:analysis / Q000378:metabolism*; D007231:Infant, Newborn; D009035:Mothers / Q000523:psychology; D011247:Pregnancy; D011256:Pregnancy Outcome; D012463:Saliva / Q000737:chemistry; D012890:Sleep / Q000502:physiology*; D055815:Young Adult
chemical_list: D006854:Hydrocortisone