title: Hyperthyroidism Improves the Pathological Condition of Nonalcoholic Steatohepatitis: A Case of Nonalcoholic Steatohepatitis with Graves' Disease.
abstract: 3,5,3'-triiodo-L-thyronine regulates the glucose metabolism, lipid metabolism, and hepatic steatosis. Several groups have shown the relationships between hypothyroidism and nonalcoholic fatty liver and hypothyroidism and nonalcoholic steatohepatitis (NASH). However, the effect of hyperthyroidism on NASH has not yet been investigated. We herein report effects of thyroid hormone on the pathological condition of NASH in a patient with NASH complicated by Graves' disease. In our case, the liver enzyme level improved with the increasing thyroid hormone level; however, the liver enzyme level was aggravated with the improving thyroid hormone level. Therefore, hyperthyroidism may improve the pathological condition of NASH.
authors.affiliation: Department of Gastroenterology and Metabology, Ehime University Graduate School of Medicine, Japan.
authors.forename: Teruki
authors.initials: T
authors.lastname: Miyake
authors.forename: Bunzo
authors.initials: B
authors.lastname: Matsuura
authors.forename: Shinya
authors.initials: S
authors.lastname: Furukawa
authors.forename: Yasuhiko
authors.initials: Y
authors.lastname: Todo
authors.forename: Shin
authors.initials: S
authors.lastname: Yamamoto
authors.forename: Osamu
authors.initials: O
authors.lastname: Yoshida
authors.forename: Yusuke
authors.initials: Y
authors.lastname: Imai
authors.forename: Takao
authors.initials: T
authors.lastname: Watanabe
authors.forename: Yasunori
authors.initials: Y
authors.lastname: Yamamoto
authors.forename: Masashi
authors.initials: M
authors.lastname: Hirooka
authors.forename: Yoshio
authors.initials: Y
authors.lastname: Tokumoto
authors.forename: Teru
authors.initials: T
authors.lastname: Kumagi
authors.forename: Masanori
authors.initials: M
authors.lastname: Abe
authors.forename: Hirotaka
authors.initials: H
authors.lastname: Seike
authors.forename: Shozo
authors.initials: S
authors.lastname: Miyauchi
authors.forename: Yoichi
authors.initials: Y
authors.lastname: Hiasa
mesh_terms: D006111:Graves Disease / Q000150:complications* / Q000473:pathology; D006801:Humans; D006980:Hyperthyroidism / Q000150:complications* / Q000473:pathology; D008099:Liver / Q000473:pathology; D008111:Liver Function Tests; D008297:Male; D065626:Non-alcoholic Fatty Liver Disease / Q000150:complications* / Q000473:pathology