title: The early years of lipoprotein research: from discovery to clinical application.
abstract: This review outlines major milestones in the first four decades of lipoprotein research beginning with their discovery nearly 90 years ago. It focuses on the contributions of some of the key investigators during this era, and findings that set the stage for widespread clinical implementation of lipoprotein testing for evaluation and management of CVD risk.
authors.affiliation: Children's Hospital Oakland Research Institute, Oakland, CA 94609-1673. Electronic address: psiri@chori.org.
authors.forename: Patty W
authors.initials: PW
authors.lastname: Siri-Tarino
authors.affiliation: Children's Hospital Oakland Research Institute, Oakland, CA 94609-1673. Electronic address: rkrauss@chori.org.
authors.forename: Ronald M
authors.initials: RM
authors.lastname: Krauss
mesh_terms: D000818:Animals; D035843:Biomedical Research / Q000266:history*; D002318:Cardiovascular Diseases / Q000266:history / Q000378:metabolism*; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D008074:Lipoproteins / Q000378:metabolism*
chemical_list: D008074:Lipoproteins
keywords: atherosclerosis; cholesterol; history; low density lipoprotein