title: Bilateral Cytomegalovirus Retinitis in a Patient with Systemic Lupus Erythematosus.
abstract: OBJECTIVE
  The purpose of this study was to report the case of a patient who underwent vitrectomy for bilateral rhegmatogenous retinal detachment caused by cytomegalovirus (CMV) retinitis while undergoing steroid and immunosuppressant therapy for systemic lupus erythematosus (SLE).
  
  
  METHODS
  We report on a 29-year-old female who was undergoing steroids and immunosuppressants treatment for SLE at Osaka Medical College Hospital, Takatsuki City, Japan. Examination of the patient due to prolonged and worsening diarrhea revealed positive test results for C7-HRP, and she was diagnosed with CMV colitis. She was subsequently admitted to the hospital and started on intravenous ganciclovir for treatment. Approximately 1.5 months later, her primary complaint was deterioration of the upper visual field in her left eye, and she was then referred to the Department of Ophthalmology. Numerous granular exudative spots were found around the lower retinal area of her left eye with retinal breaks that had developed in an area of retinal necrosis that resulted in retinal detachment. After time was allowed for the patient's general condition to improve, a vitrectomy was performed on that eye. The patient subsequently developed a similar retinal detachment in her right eye, for which she underwent a vitrectomy. Although the patient required multiple surgeries on both eyes, her retinas currently remain reattached and the inflammation has subsided.
  
  
  CONCLUSIONS
  The findings of this study show that strict attention must be paid to SLE patients on immunosuppressive therapy due to the possible association of CMV retinitis.
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Masaya
authors.initials: M
authors.lastname: Haze
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Takatoshi
authors.initials: T
authors.lastname: Kobayashi
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Keigo
authors.initials: K
authors.lastname: Kakurai
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Hiromi
authors.initials: H
authors.lastname: Shoda
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Nanae
authors.initials: N
authors.lastname: Takai
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan; Takeda Eye Clinic, Osaka City, Japan.
authors.forename: Sayako
authors.initials: S
authors.lastname: Takeda
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan; Tada Eye Clinic, Ikeda City, Japan.
authors.forename: Rei
authors.initials: R
authors.lastname: Tada
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan; Maruyama Eye Clinic, Takatsuki City, Japan.
authors.forename: Kouichi
authors.initials: K
authors.lastname: Maruyama
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Teruyo
authors.initials: T
authors.lastname: Kida
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takasuki City, Japan.
authors.forename: Tsunehiko
authors.initials: T
authors.lastname: Ikeda
keywords: Cytomegalovirus retinitis; Retinal detachment; Systemic lupus erythematosus; Vitrectomy