title: Hippo's Q for a big liver.
abstract: The Hippo pathway is a key regulator of organ size that has also been implicated in tumorigenesis. Yap, one of the effectors of Hippo signalling, is now reported to support these functions by promoting glutamine synthesis.
authors.affiliation: Cancer Metabolism Laboratory, The Francis Crick Institute, The Ridgeway, London NW7 1AA, UK.
authors.forename: Dimitrios
authors.initials: D
authors.lastname: Anastasiou
mesh_terms: D000818:Animals; D063646:Carcinogenesis / Q000235:genetics*; D005973:Glutamine / Q000378:metabolism; D000090683:Hippo Signaling Pathway; D006801:Humans; D008099:Liver / Q000378:metabolism*; D009929:Organ Size / Q000235:genetics / Q000502:physiology; D017346:Protein Serine-Threonine Kinases / Q000378:metabolism
chemical_list: D005973:Glutamine; D017346:Protein Serine-Threonine Kinases