title: Systemic Inflammatory Syndrome Associated with a Case of Jugular Paraganglioma.
abstract: Jugular paraganlioma is a benign, slow-growing tumor originating from the paraganglion cells and it is associated with catecholamine secretion. Paragangliomas can secrete Interleukin-6 (IL-6) and present as a systemic inflammatory syndrome; these characteristics have not been previously associated with jugular paragangliomas. A 63-year-old man with a jugular tumor in the skull base was referred to our hospital for an evaluation of pyrexia, back pain, and acute inflammation. His serum IL-6 level was elevated on admission and it decreased after radiotherapy. This is the first known case of a jugular paraganglioma exhibiting systemic inflammatory syndrome.
authors.affiliation: Department of General Internal Medicine, Hiroshima University Hospital, Japan.
authors.forename: Ayuko
authors.initials: A
authors.lastname: Sokabe
authors.forename: Masafumi
authors.initials: M
authors.lastname: Mizooka
authors.forename: Rinne
authors.initials: R
authors.lastname: Sakemi
authors.forename: Tomoki
authors.initials: T
authors.lastname: Kobayashi
authors.forename: Nobusuke
authors.initials: N
authors.lastname: Kishikawa
authors.forename: Kenichi
authors.initials: K
authors.lastname: Yokobayashi
authors.forename: Keishi
authors.initials: K
authors.lastname: Kanno
authors.forename: Susumu
authors.initials: S
authors.lastname: Tazuma
mesh_terms: D000368:Aged; D005925:Glomus Jugulare Tumor / Q000150:complications* / Q000532:radiotherapy; D006258:Head and Neck Neoplasms / Q000150:complications* / Q000532:radiotherapy; D006801:Humans; D015850:Interleukin-6 / Q000097:blood; D008297:Male; D018746:Systemic Inflammatory Response Syndrome / Q000150:complications* / Q000276:immunology*
chemical_list: D015850:Interleukin-6