title: Exercise therapy in patients with hip osteoarthritis: Effect on hip muscle strength and safety aspects of exercise-results of a randomized controlled trial.
abstract: OBJECTIVE
  To evaluate the effect of an exercise therapy concept (the Tübingen exercise therapy approach THüKo) for increasing hip muscle strength (HMS) in patients with hip osteoarthritis (OA), and to investigate whether patients do adhere to the intervention and if there are any adverse events related to the intervention.
  
  
  METHODS
  A total of 210 hip OA patients (89 females, 121 males) were randomized into a 12-week exercise intervention (THüKo) including group sessions (1/week) and home exercising (2/week), a placebo ultrasound group (1/week) or a control group (no treatment). HMS was measured as isometric peak torque of hip abduction, adduction, flexion, and extension. Adherence to exercise and safety aspects were monitored as additional outcomes.
  
  
  RESULTS
  Baseline adjusted post intervention HMS of the THüKo group were higher compared to the control group (differences of 0.11-0.27 Nm/kg, p < 0.01) and to the placebo ultrasound group (differences of 0.09-0.19 Nm/kg, p < 0.01). Adherence to exercise was high (about 90%). No subject had to refuse from training because of an exercise related adverse event and exercise related pain was only of intermittent nature without sustainable adverse effects.
  
  
  CONCLUSIONS
  The Tübingen exercise therapy approach has shown to have a significant positive effect on HMS. Its implementation has shown to be feasible and safe according to the percentage of exercise participation and the absence of sustainable adverse events.
authors.affiliation: a Department of Sports Medicine , University Hospital , Tuebingen , Germany and.|b Institute of Occupational Medicine, Social Medicine and Health Services Research, University Hospital , Tuebingen , Germany.
authors.forename: Benjamin
authors.initials: B
authors.lastname: Steinhilber
authors.affiliation: a Department of Sports Medicine , University Hospital , Tuebingen , Germany and.
authors.forename: Georg
authors.initials: G
authors.lastname: Haupt
authors.affiliation: a Department of Sports Medicine , University Hospital , Tuebingen , Germany and.
authors.forename: Regina
authors.initials: R
authors.lastname: Miller
authors.affiliation: a Department of Sports Medicine , University Hospital , Tuebingen , Germany and.
authors.forename: Pia
authors.initials: P
authors.lastname: Janssen
authors.affiliation: a Department of Sports Medicine , University Hospital , Tuebingen , Germany and.
authors.forename: Inga
authors.initials: I
authors.lastname: Krauss
mesh_terms: D000328:Adult; D000368:Aged; D005081:Exercise Therapy / Q000009:adverse effects / Q000379:methods*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D053580:Muscle Strength; D015207:Osteoarthritis, Hip / Q000628:therapy*; D010147:Pain Measurement; D061214:Patient Safety; D016059:Range of Motion, Articular
keywords: Dose-response; Gender; Hip; Osteoarthritis; Strength training