title: Confocal Cornea Microscopy Detects Involvement of Corneal Nerve Fibers in a Patient with Light-Chain Amyloid Neuropathy Caused by Multiple Myeloma: A Case Report.
abstract: Changes in the subbasal corneal plexus detected by confocal cornea microscopy (CCM) have been described for various types of neuropathy. An involvement of these nerves within light-chain (AL) amyloid neuropathy (a rare cause of polyneuropathy) has never been shown. Here, we report on a case of a patient suffering from neuropathy caused by AL amyloidosis and underlying multiple myeloma. Small-fiber damage was detected by CCM.
authors.affiliation: Department of Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr University Bochum, Bochum, Germany.
authors.forename: Dietrich
authors.initials: D
authors.lastname: Sturm
authors.affiliation: Department of Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr University Bochum, Bochum, Germany.
authors.forename: Tobias
authors.initials: T
authors.lastname: Schmidt-Wilcke
authors.affiliation: Department of Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr University Bochum, Bochum, Germany.
authors.forename: Tineke
authors.initials: T
authors.lastname: Greiner
authors.affiliation: Department of Pain Medicine, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr University Bochum, Bochum, Germany.
authors.forename: Christoph
authors.initials: C
authors.lastname: Maier
authors.affiliation: University Eye Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
authors.forename: Marc
authors.initials: M
authors.lastname: Schargus
authors.affiliation: Department of Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr University Bochum, Bochum, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Tegenthoff
authors.affiliation: Department of Neurology, Berufsgenossenschaftliches Universitätsklinikum Bergmannsheil, Ruhr University Bochum, Bochum, Germany.
authors.forename: Matthias
authors.initials: M
authors.lastname: Vorgerd
keywords: Amyloid neuropathy; Confocal cornea microscopy; Multiple myeloma; Skin biopsy; Small-fiber neuropathy