title: Preparation of Optically Pure Tertiary Phosphine Oxides via the Addition of P-Stereogenic Secondary Phosphine Oxide to Activated Alkenes.
abstract: Functionalized P,C-stereogenic tertiary phosphine oxides were prepared by the addition of (RP)-menthyl phenylphosphine oxide to activated olefins, in high drP and drC, and were isolated in excellent yields. The reaction was readily catalyzed by Ca(OH)2 or occurred with gentle heating. A wide range of substrates, including vinyl ketones, esters, nitriles, and nitro alkenes, can be used in the reaction.
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University , Liaocheng, Shandong 252059, China.
authors.forename: Ji-Ping
authors.initials: JP
authors.lastname: Wang
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University , Liaocheng, Shandong 252059, China.
authors.forename: Shao-Zhen
authors.initials: SZ
authors.lastname: Nie
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University , Liaocheng, Shandong 252059, China.
authors.forename: Zhong-Yang
authors.initials: ZY
authors.lastname: Zhou
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University , Liaocheng, Shandong 252059, China.
authors.forename: Jing-Jing
authors.initials: JJ
authors.lastname: Ye
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University , Liaocheng, Shandong 252059, China.
authors.forename: Jing-Hong
authors.initials: JH
authors.lastname: Wen
authors.affiliation: College of Chemistry and Chemical Engineering, Liaocheng University , Liaocheng, Shandong 252059, China.
authors.forename: Chang-Qiu
authors.initials: CQ
authors.lastname: Zhao