title: A Short Review of Chemical Reaction Database Systems, Computer-Aided Synthesis Design, Reaction Prediction and Synthetic Feasibility.
abstract: This article is the text for a pedagogical lecture to be given at the Strasbourg Summer School in Chemoinformatics in June 2104. It covers a very wide range of reaction topics including structure and reaction representation, reaction centers, atom-to-atom mapping, reaction retrieval systems, computer-aided synthesis design, retrosynthesis, reaction prediction and synthetic feasibility. In the time available the coverage of each topic can only be cursory; the main usefulness of this article to the research community is the extensive bibliography.
authors.affiliation: 6 Berwick Court, Holmes Chapel, Cheshire, CW4 7HZ, UK phone/fax:+44 1477 533837. wendy@warr.com.
authors.forename: Wendy A
authors.initials: WA
authors.lastname: Warr
keywords: Atom-to-atom mapping; Computer-aided synthesis design; Reaction prediction; Reaction retrieval systems; Synthetic feasibility