title: A Pilot Study on Culottes versus Crossover Single Stenting for True Coronary Bifurcation Lesions.
abstract: BACKGROUND
  The purpose of our study was to compare clinical and angiographic outcomes of planned culottes technique with that of provisional crossover single stenting in the treatment of true coronary bifurcation lesions (CBL) with drug-eluting stent (DES).
  
  
  METHODS
  True CBL patients (n = 104) were randomly assigned to either the provisional stenting of the side branch (crossover group) or the culottes group. Additional side branch (SB) stenting in the crossover group was required if there was thrombolysis in myocardial infarction flow ≤ 1 flow). The primary end point was the occurrence of major adverse cardiac events (MACE) at nine months, including cardiac death, myocardial infarction, target lesion/vessel revascularization and in-stent thrombosis. The secondary end point was angiographic in-segment restenosis at nine months.
  
  
  RESULTS
  The rate of MACE at nine months was similar between the crossover and culottes groups (7.7% vs. 7.7%, p = 1.000). Additional SB stenting in the crossover group was required in 3.8% of patients. There was one procedural occlusion of SB in the crossover group. At nine months, the rate of in-segment restenosis was similar in the parent main vessel (0% vs. 1.9%, p = 1.000), main branch (1.9% vs. 7.7%, p = 0.363) and SB (17.3% vs. 9.6%, p = 0.250) between the crossover and culottes groups, respectively.
  
  
  CONCLUSIONS
  This study demonstrated that there is no significant difference in cumulative MACE or in-segment restenosis between crossover and culottes groups. Larger randomized clinical trials are warranted to re-evaluate the outcomes of the provisional crossover stenting versus the culottes stenting techniques utilizing DES for true CBL.
authors.affiliation: Department of Cardiology, Union Hospital, Fujian Medical University, Fujian 350001, P.R. China.
authors.forename: Linlin
authors.initials: L
authors.lastname: Zhang
authors.affiliation: Department of Cardiology, Union Hospital, Fujian Medical University, Fujian 350001, P.R. China.
authors.forename: Wenliang
authors.initials: W
authors.lastname: Zhong
authors.affiliation: Department of Cardiology, Union Hospital, Fujian Medical University, Fujian 350001, P.R. China.
authors.forename: Yukun
authors.initials: Y
authors.lastname: Luo
authors.affiliation: Department of Cardiology, Union Hospital, Fujian Medical University, Fujian 350001, P.R. China.
authors.forename: Lianglong
authors.initials: L
authors.lastname: Chen
keywords: Angioplasty; Bifurcation lesion; Clinical trial; Coronary stenting; Drug-eluting stent; Restenosis