title: Quality of life, depression and dietary intake in Obstructive Sleep Apnea patients.
abstract: BACKGROUND
  The aim of this study was to analyze the association between depression, quality of life and dietary intake in newly diagnosed Obstructive Sleep Apnea (OSA) patients.
  
  
  METHODS
  From 153 eligible patients suffering from sleep disturbances, 64 met inclusion and exclusion criteria. The polysomnography was used for OSA diagnosis. The quality of life (QOL) was assessed by WHOQOL-BREF questionnaire, self-reported chronotype by morningness-eveningness questionnaire and level of depression by Beck's Depression Inventory. Blood pressure and parameters of glucose and lipid metabolism were assessed by routine methods. The dietary intake was evaluated by 24-hr dietary recalls.
  
  
  RESULTS
  Significantly negative associations were found between depression inventory and QOL. Better QOL for physical health and social relationships was observed in the "definitely morning" chronotype. The "morning type" of patients was positively related to the intake of fat, monounsaturated fatty acids and vitamin B12. Correlations between QOL and diastolic blood pressure, HDL-cholesterol, TG, fasting glucose, as well as protein and vitamin B6 intake were found.
  
  
  CONCLUSIONS
  In conclusion, both chornotype and depression influence QOL in OSA patients where morning type is associated with better physical health and social relationships and increase in depression index deteriorate physical health, psychological and social relationship QOL domains. QOL as well as depression and chornotype are also influenced by selected cardio-metabolic factors and dietary intake.
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthurt-Scheunert Alee Str. 114-116, 14558, Nuthetal, Germany. stelmach@dife.de.|Department of Pediatric Gastroenterology and Metabolic Diseases, Poznan University of Medical Sciences, Szpitalna Str 27/33, 60-572, Poznan, Poland. stelmach@dife.de.
authors.forename: Marta
authors.identifier: http://orcid.org/0000-0001-5944-1642
authors.initials: M
authors.lastname: Stelmach-Mardas
authors.affiliation: Department of Human Nutrition and Hygiene, Poznan University of Life Sciences, Wojska Polskiego Str. 28, 60-637, Poznań, Poland.
authors.forename: Marcin
authors.initials: M
authors.lastname: Mardas
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthurt-Scheunert Alee Str. 114-116, 14558, Nuthetal, Germany.
authors.forename: Khalid
authors.initials: K
authors.lastname: Iqbal
authors.affiliation: Department of Development and Regeneration, Laboratory of Skeletal Cell Biology and Physiology, Skeletal Biology and Engineering Research Center, O&N 1 Herestraat 49 box 813, KU Leuven, Leuven, Belgium.
authors.forename: Robert J
authors.initials: RJ
authors.lastname: Tower
authors.affiliation: Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Arthurt-Scheunert Alee Str. 114-116, 14558, Nuthetal, Germany.
authors.forename: Heiner
authors.initials: H
authors.lastname: Boeing
authors.affiliation: Department of Pulmonology, Allergology and Respiratory Oncology, Poznan University of Medical Sciences, Szamarzewskiego Str. 84, 60-569, Poznań, Poland.
authors.forename: Tomasz
authors.initials: T
authors.lastname: Piorunek
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D003866:Depressive Disorder / Q000150:complications* / Q000523:psychology; D004032:Diet / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D017286:Polysomnography; D011569:Psychiatric Status Rating Scales; D011788:Quality of Life / Q000523:psychology*; D020181:Sleep Apnea, Obstructive / Q000175:diagnosis / Q000523:psychology*; D011795:Surveys and Questionnaires
keywords: Biomarkers; Chronotype; Diet; Sleep Apnea