title: Intracranial Inflammatory Myofibroblastic Tumor with Sarcomatous Local Recurrence.
abstract: METHODS
  A 20-year-old woman presented with a rare intracranial inflammatory myofibroblastic tumor (IMT) manifesting as headache and insomnia. Magnetic resonance imaging showed a tumorous lesion with heterogeneous enhancement at the right temporal lobe, as well as perifocal edema with midline shift. The tumor was totally resected with the margin free. Pathologic examination showed IMT with myofibroblastic cells admixed with collagen fibers. Sarcomatous change in morphology was observed in tumor recurrence within 7 months.
  
  
  CONCLUSIONS
  Surgical resection and whole brain radiation are recommended in patients with IMT.
authors.affiliation: Division of Gastroenterology and Hepatology, Department of Internal Medicine, Ping-Tung Christian Hospital, Ping-Tung, Taiwan.
authors.forename: Yoen-Young
authors.initials: YY
authors.lastname: Chuah
authors.affiliation: Division of Hematology and Hematologic Malignancies, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah, USA.
authors.forename: Tsewang
authors.initials: T
authors.lastname: Tashi
authors.affiliation: Department of Radiology, Ping-Tung Christian Hospital, Ping-Tung, Taiwan.
authors.forename: Cherng-Gueih
authors.initials: CG
authors.lastname: Shy
authors.affiliation: Department of Pathology, Ping-Tung Christian Hospital, Ping-Tung, Taiwan.
authors.forename: Jean-Shiunn
authors.initials: JS
authors.lastname: Shyu
authors.affiliation: Division of Neurosurgery, Department of Surgery, Ping-Tung Christian Hospital, Ping-Tung, Taiwan.
authors.forename: Ming-Jeng
authors.initials: MJ
authors.lastname: Dong
authors.affiliation: Division of Hematology & Oncology, Department of Internal Medicine, Ping-Tung Christian Hospital, Ping-Tung, Taiwan. Electronic address: erjunghsueh@gmail.com.
authors.forename: Er-Jung
authors.initials: EJ
authors.lastname: Hsueh
mesh_terms: D001932:Brain Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D002471:Cell Transformation, Neoplastic / Q000473:pathology; D003399:Craniotomy / Q000379:methods; D003937:Diagnosis, Differential; D005260:Female; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology* / Q000532:radiotherapy*; D009379:Neoplasms, Muscle Tissue / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery*; D018714:Radiotherapy, Adjuvant / Q000379:methods; D012509:Sarcoma / Q000517:prevention & control*; D016896:Treatment Outcome; D055815:Young Adult
keywords: Anaplastic lymphoma kinase; Brain; Inflammatory myofibroblastic tumor; Recurrence; Sarcomatous change