title: Perioperative Cefovecin to Reduce the Incidence of Urinary Tract Infection in Dogs Undergoing Hemilaminectomy.
abstract: The prevalence of urinary tract infections (UTIs) in dogs with Type I intervertebral disc extrusion has been reported as high as 38% within 6 wk of surgery. Proper treatment of a UTI is important with myelopathy because it is a risk factor for persistent infection and reinfection in dogs. The study authors' investigated the incidence of UTIs in dogs having received either cefovecin or cefazolin as a preoperative prophylactic antibiotic for thoracolumbar hemilaminectomy. Thirty-nine dogs were retrospectively identified and assigned to groups based on preoperative antibiotic administration and postoperative urinary tract management. Urinalysis and urine culture performed preoperatively, at 2 wk, and at 6 wk, were reviewed to determine the incidence of UTIs. Urinary tract management, grade of neurologic deficit, time to ambulation, and time to voluntary urination were identified to evaluate for additional risk factors. No significant prevalence of UTI incidence was appreciated between the cefovecin and cefazolin groups. Patients with higher grades of neurologic deficit and that took longer to regain ambulation and voluntary urination were at significantly greater risk for UTIs throughout the postoperative period. This study reemphasizes the importance of continued surveillance for UTIs in patients with prolonged neurologic recovery.
authors.affiliation: From the VCA Clinical Studies Department, Katonah Bedford Veterinary Center, Bedford Hills, NY (J.D.P., P.J.B.); and the Surgery Department (J.J.B.) and the Neurology Department (J.M.B.), Animal Specialty Center, Yonkers, NY.
authors.forename: Joseph D
authors.initials: JD
authors.lastname: Palamara
authors.affiliation: From the VCA Clinical Studies Department, Katonah Bedford Veterinary Center, Bedford Hills, NY (J.D.P., P.J.B.); and the Surgery Department (J.J.B.) and the Neurology Department (J.M.B.), Animal Specialty Center, Yonkers, NY.
authors.forename: Jennifer J
authors.initials: JJ
authors.lastname: Bonczynski
authors.affiliation: From the VCA Clinical Studies Department, Katonah Bedford Veterinary Center, Bedford Hills, NY (J.D.P., P.J.B.); and the Surgery Department (J.J.B.) and the Neurology Department (J.M.B.), Animal Specialty Center, Yonkers, NY.
authors.forename: Jason M
authors.initials: JM
authors.lastname: Berg
authors.affiliation: From the VCA Clinical Studies Department, Katonah Bedford Veterinary Center, Bedford Hills, NY (J.D.P., P.J.B.); and the Surgery Department (J.J.B.) and the Neurology Department (J.M.B.), Animal Specialty Center, Yonkers, NY.
authors.forename: Philip J
authors.initials: PJ
authors.lastname: Bergman
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000008:administration & dosage / Q000494:pharmacology; D001424:Bacterial Infections / Q000209:etiology / Q000517:prevention & control / Q000662:veterinary; D002511:Cephalosporins / Q000008:administration & dosage / Q000494:pharmacology*; D004283:Dog Diseases / Q000517:prevention & control* / Q000601:surgery; D004285:Dogs; D007796:Laminectomy / Q000009:adverse effects / Q000379:methods / Q000662:veterinary*; D019990:Perioperative Care; D011183:Postoperative Complications / Q000517:prevention & control / Q000662:veterinary*; D012189:Retrospective Studies; D014552:Urinary Tract Infections / Q000517:prevention & control / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D002511:Cephalosporins; C516253:cefovecin