title: Bacterial Leakage of Mineral Trioxide Aggregate, Calcium-Enriched Mixture and Biodentine as Furcation Perforation Repair Materials in Primary Molars.
abstract: BACKGROUND
  Adequate seal of iatrogenically perforated area within the root canal system can improve the long term treatment prognosis. This in vitro study evaluated the sealing ability of mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM) cement and Biodentine in repair of furcation perforation in primary molars.
  
  
  METHODS
  A total of 61 freshly extracted primary mandibular second molars were randomly divided into three groups (n=17) and 10 teeth were put in negative (without perforation, n=5) and positive (perforated without repair, n=5) control groups. Turbidity was used as the criteria of bacterial leakage, when detected in the model of dual-chamber leakage. Data were analyzed using the Chi-Square and Kaplan-Meier survival analysis in SPSS software. The level of significance was set at 0.05.
  
  
  RESULTS
  All positive samples showed turbidity, whereas none of the negative samples allowed bacterial leakage. There was no significant difference between the number of turbidity samples in repaired teeth with all test materials (P=0.13). No significant difference was also detected in the mean survival time (P>0.05).
  
  
  CONCLUSIONS
  CEM cement and Biodentine showed promising results as perforation repair materials and can be recommended as suitable alternatives of MTA for repair of furcation perforation of primary molars.
authors.affiliation: Children and Adolescent Health Research Center, Oral and Dental Disease Research Center, Department of Pediatric Dentistry, School of Dentistry, Zahedan University of Medical Sciences, Zahedan, Iran;
authors.forename: Nahid
authors.initials: N
authors.lastname: Ramazani
authors.affiliation: Dentist, Zahedan University of Medical Sciences, Zahedan, Iran.
authors.forename: Parisa
authors.initials: P
authors.lastname: Sadeghi
keywords: Biodentine; Biomaterial; Calcium-Enriched Mixture; Furcation Perforation; Mineral Trioxide Aggregate; Perforation Repair; Sealability