title: Direct NHC-catalysed redox amidation using CO2 for traceless masking of amine nucleophiles.
abstract: The N-heterocyclic carbene (NHC)-catalysed redox amidation reaction is poorly developed and usually requires catalytic co-additives for electron-rich amine nucleophiles. We report a masking strategy (using CO2) that couples release of the free amine nucleophile to catalytic turnover, and in doing so, enables direct catalytic redox amidation of electron-rich amines.
authors.affiliation: Department of Chemistry, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK. m.fuchter.imperial.ac.uk.
authors.forename: Robert W M
authors.initials: RW
authors.lastname: Davidson
authors.forename: Matthew J
authors.initials: MJ
authors.lastname: Fuchter