title: Scaffold-free, stem cell-based cartilage repair.
abstract: Various approaches to treat articular cartilage have been widely investigated due to its poor intrinsic healing capacity. Stem cell-based therapy could be a promising approach as an alternative to chondrocyte-based therapy and some of these therapies have been already applied in clinical condition. This review discusses the current development of stem cell-based therapies in cartilage repair, specifically focusing on scaffold-free approaches.
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Yukihiko
authors.initials: Y
authors.lastname: Yasui
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Wataru
authors.initials: W
authors.lastname: Ando
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Kazunori
authors.initials: K
authors.lastname: Shimomura
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Kota
authors.initials: K
authors.lastname: Koizumi
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Chijimatsu
authors.initials: C
authors.lastname: Ryota
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Shuichi
authors.initials: S
authors.lastname: Hamamoto
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Masato
authors.initials: M
authors.lastname: Kobayashi
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan.
authors.forename: Hideki
authors.initials: H
authors.lastname: Yoshikawa
authors.affiliation: Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, Osaka, Japan; Institute for Medical Science in Sports, Osaka Health Science University, Osaka, Japan; Center for Advanced Medical Engineering and Informatics, Osaka University, Osaka, Japan.
authors.forename: Norimasa
authors.initials: N
authors.lastname: Nakamura
keywords: Cartilage repair; Mesenchymal stem cell; Scaffold free; Stem cell-based therapy