title: Association Between Kidney Cancer and Occupational Exposure to Trichloroethylene.
abstract: This study investigates the association between occupational exposure to trichloroethylene (TCE) and kidney cancer, as this correlation has been questioned.
  
  
  
  The incidence of cancers was studied in a dynamic cohort of 997 male workers who for many years had been occupationally exposed to TCE.
  
  
  
  During a 50-year observation period, 13 cases of kidney cancer were observed (7.5 expected) with a standardized incidence ratio of 1.7 and a 95% confidence interval of 1.0 to 3.0. Four other cases, not included in the SIR analysis, were also observed. Long-term TCE exposure was positively confirmed for 14 of the 17 incident cases. There is reason to assume that the remaining cases also had been exposed to TCE.
  
  
  
  The present study supports the view that TCE is a kidney carcinogen.
authors.affiliation: Department of Occupational Medicine, St. Olavs University Hospital in Trondheim (Mr Buhagen, Dr Grønskag, Ms Ragde, Dr Hilt); and Department of General Practice and Community Medicine, Faculty of Medicine, NTNU, Norwegian University of Science and Technology, Trondheim, Norway (Mr Buhagen, Drs Grønskag, Hilt).
authors.forename: Morten
authors.initials: M
authors.lastname: Buhagen
authors.forename: Anna
authors.initials: A
authors.lastname: Grønskag
authors.forename: Siri Fenstad
authors.initials: SF
authors.lastname: Ragde
authors.forename: Bjørn
authors.initials: B
authors.lastname: Hilt
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D006801:Humans; D015994:Incidence; D007680:Kidney Neoplasms / Q000453:epidemiology*; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D014241:Trichloroethylene / Q000009:adverse effects*
chemical_list: D014241:Trichloroethylene