title: Therapeutical Management for Ocular Rosacea.
abstract: OBJECTIVE
  The purpose of this study is to describe a case of ocular rosacea with a very complex evolution. Rosacea is a chronic dermatological disease that may affect the ocular structures up to 6-72% of all cases. This form is often misdiagnosed, which may lead to long inflammatory processes with important visual consequences for affected patients. Therefore, an early diagnosis and an adequate treatment are important.
  
  
  METHODS
  We report the case of a 43-year-old patient who had several relapses of what seemed an episode of acute bacterial conjunctivitis. Two weeks later, he developed a corneal ulcer with a torpid evolution including abundant intrastromal infiltrators and calcium deposits. He was diagnosed with ocular rosacea and treated with systemic doxycycline and topical protopic.
  
  
  RESULTS
  A coating with amniotic membrane was placed in order to heal the ulcer, but a deep anterior lamellar keratoplasty to restore the patient's vision because of the corneal transparency loss was necessary.
  
  
  CONCLUSIONS
  Ocular rosacea includes multiple ophthalmic manifestations ranging from inflammation of the eyelid margin and blepharitis to serious corneal affectations. A delayed diagnosis can result in chronic inflammatory conditions including keratinization and loss of corneal transparency, which lead to important visual sequelae for affected patients.
authors.affiliation: Hospital Royo Villanova, Zaragoza, Spain; Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors.forename: Gloria
authors.initials: G
authors.lastname: López-Valverde
authors.affiliation: Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria de Aragón (IIS Aragon), Zaragoza, Spain.
authors.forename: Elena
authors.initials: E
authors.lastname: Garcia-Martin
authors.affiliation: Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria de Aragón (IIS Aragon), Zaragoza, Spain.
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Larrosa-Povés
authors.affiliation: Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria de Aragón (IIS Aragon), Zaragoza, Spain.
authors.forename: Vicente
authors.initials: V
authors.lastname: Polo-Llorens
authors.affiliation: Hospital Universitario Miguel Servet, Zaragoza, Spain; Instituto de Investigación Sanitaria de Aragón (IIS Aragon), Zaragoza, Spain.
authors.forename: Luis E
authors.initials: LE
authors.lastname: Pablo-Júlvez
keywords: Amniotic membrane; Deep anterior lamellar keratoplasty; Management; Ocular symptoms; Rosacea