title: Radiotherapy-associated dental extractions and osteoradionecrosis.
abstract: Preradiotherapy dental extractions often form a part of the management plan for patients treated with radiotherapy for head and neck cancers in order to prevent complications, such as osteoradionecrosis. There is contention about whether these extractions should be performed and the timing of such extractions. The purpose of this study was to determine if pre-RT extractions were associated with the development of osteoradionecrosis of the jaws.
  
  
  
  Retrospective data on patients treated with RT for oropharyngeal cancer were pooled with a cross-sectional survey.
  
  
  
  Pre-radiotherapy dental extractions were associated with a statistically significant increase in the risk of developing ORN.
  
  
  
  Pre-radiotherapy dental extractions do not protect against the development of osteoradionecrosis. © 2016 Wiley Periodicals, Inc. Head Neck 39: 128-132, 2017.
authors.affiliation: University of Queensland School of Medicine, Queensland, Brisbane, Australia.|Department of Dental Surgery, University of Adelaide School of Dentistry, Adelaide, Australia.
authors.forename: Nicholas M
authors.initials: NM
authors.lastname: Beech
authors.affiliation: University of Queensland School of Medicine, Queensland, Brisbane, Australia.|Department of Radiation Oncology, Princess Alexandra Hospital, Brisbane, Australia.
authors.forename: Sandro
authors.initials: S
authors.lastname: Porceddu
authors.affiliation: University of Queensland School of Medicine, Queensland, Brisbane, Australia.|Department of Oral and Maxillofacial Surgery, Royal Brisbane and Women's Hospital, Queensland, Australia.
authors.forename: Martin D
authors.initials: MD
authors.lastname: Batstone
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000188:drug therapy / Q000532:radiotherapy*; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D008297:Male; D008336:Mandibular Diseases / Q000175:diagnosis / Q000209:etiology*; D008439:Maxillary Diseases / Q000175:diagnosis / Q000209:etiology*; D008875:Middle Aged; D009910:Oral Hygiene; D009959:Oropharyngeal Neoplasms / Q000188:drug therapy / Q000532:radiotherapy*; D010025:Osteoradionecrosis / Q000175:diagnosis / Q000209:etiology*; D011879:Radiotherapy Dosage; D012189:Retrospective Studies; D014081:Tooth Extraction
keywords: dental; dental extractions; head and neck oncology; osteoradionecrosis; radiotherapy