title: Tunable resistive pulse sensing: potential applications in nanomedicine.
abstract: An accurate characterization of nanomaterials used in clinical diagnosis and therapeutics is of paramount importance to realize the full potential of nanotechnology in medicine and to avoid unexpected and potentially harmful toxic effects due to these materials. A number of technical modalities are currently in use to study the physical, chemical and biological properties of nanomaterials but they all have advantages and disadvantages. In this review, we discuss the potential of a relative newcomer, tunable resistive pulse sensing, for the characterization of nanomaterials and its applications in nanodiagnostics.
authors.affiliation: Department of Haematology, Peterborough City Hospital, Peterborough, PE3 9GZ, UK.
authors.forename: Muttuswamy
authors.initials: M
authors.lastname: Sivakumaran
authors.affiliation: Department of Chemistry, Loughborough University, Loughborough, LE11 3TU, UK.
authors.forename: Mark
authors.initials: M
authors.lastname: Platt
mesh_terms: D000818:Animals; D052157:Aptamers, Nucleotide / Q000737:chemistry; D015374:Biosensing Techniques / Q000295:instrumentation / Q000379:methods*; D016503:Drug Delivery Systems / Q000379:methods; D004867:Equipment Design; D006801:Humans; D050997:Nanomedicine / Q000295:instrumentation / Q000379:methods*; D049329:Nanostructures / Q000737:chemistry*; D036103:Nanotechnology / Q000295:instrumentation / Q000379:methods*; D055672:Static Electricity
chemical_list: D052157:Aptamers, Nucleotide
keywords: TRPS; aptamers; biosensors; exosomes; nanodiagnostics; nanomedicine; nanoparticles; nanotechnology; tunable resistive pulse sensing