title: Endobronchial metastasis of mixed germ cell tumors: two cases.
abstract: Lung metastases from extrapulmonary malignancies are common however endobronchial metastases (EBM) from nonpulmonary neoplasms are rare. A variety of extrathoracic tumors have a tendency to EBM especially breast, colon, and renal carcinomas are most frequent reported tumors however EBM of germ cell tumors are extremely rare. A 39-year-old and a 27-year-old male patient were admitted to our hospital with hemoptysis and dyspnea at different times. Both of them had a history of left orchiectomy due to mixed germ cell tumor two years and one year ago, respectively. On chest X-Ray and thorax computed tomography, first had a right upper lobe atelectasis and second had right total atelectasis. Fiberoptic bronchoscopy (FOB) performed and a vascularized endobronchial lesion (EBL) which tended to bleed was seen in the orifis of right upper lobe in the first case and right main bronchus was totally obstructed by EBL also in the second. Interventional bronchoscopy was performed via rigid bronchoscopy for biopsy and palliative treatment (argon plasma coagulation and debulking) in both two patients because of tendency to bleeding. A partial aperture was achieved at right upper lobe bronchus in the first case and total atelectasis resolved in the second case. Immunohistochemically, histopathological examinations of both patients biopsies confirmed EBM of mixed germ cell tumors. In conclusion, EBM of the germ cell tumors especially with total or partial atelectasis are extremely rare. We want to present these cases to emphasize the importance of distinguishing EBM from primary lung carcinoma which treatment and survival could be different.
authors.affiliation: Clinic of Interventional Pulmonology, Ankara Ataturk Chest Diseases and Chest Surgery Training and Research Hospital, Ankara, Turkey. drayperi@yahoo.com.
authors.forename: Ayperi
authors.initials: A
authors.lastname: Öztürk
authors.forename: Zafer
authors.initials: Z
authors.lastname: Aktaş
authors.forename: Aydın
authors.initials: A
authors.lastname: Yılmaz
mesh_terms: D001980:Bronchi / Q000473:pathology; D001984:Bronchial Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology / Q000556:secondary*; D001999:Bronchoscopy; D004417:Dyspnea / Q000209:etiology; D049669:History, 16th Century; D006801:Humans; D008297:Male; D009373:Neoplasms, Germ Cell and Embryonal / Q000000981:diagnostic imaging* / Q000556:secondary*; D013902:Radiography, Thoracic; D013736:Testicular Neoplasms / Q000473:pathology*; D014057:Tomography, X-Ray Computed; D014132:Trachea / Q000473:pathology