title: Dabigatran can cause eosinophilic pleural and pericardial effusion with blood eosinophilia.
abstract: Eosinophilic pleural effusions (EPE) account for 5%-8% of all exudative pleural effusions. A pleural effusion is defined as eosinophilic if it contains 10% or more eosinophils. We present the case of a 70-year-old man with EPE, blood eosinophilia and pericardial effusion due to dabigatran, a novel anti-thrombin agent.
authors.affiliation: Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis 68100, Greece.
authors.forename: Thanasis
authors.initials: T
authors.lastname: Voulgaris
authors.affiliation: Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis 68100, Greece.
authors.forename: Stavros
authors.initials: S
authors.lastname: Anevlavis
authors.affiliation: Department of Pathology, North Hospital, University Hospital of St. Etienne, St-Etienne, France.
authors.forename: Georgia
authors.initials: G
authors.lastname: Karpathiou
authors.affiliation: Department of Pathology, North Hospital, University Hospital of St. Etienne, St-Etienne, France.
authors.forename: Fabien
authors.initials: F
authors.lastname: Forest
authors.affiliation: Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis 68100, Greece.
authors.forename: Andreas
authors.initials: A
authors.lastname: Koulelidis
authors.affiliation: Department of Respiratory Medicine, Medical School, Democritus University of Thrace, Alexandroupolis 68100, Greece.
authors.forename: Marios
authors.initials: M
authors.lastname: Froudarakis
mesh_terms: D000368:Aged; D000069604:Dabigatran / Q000009:adverse effects* / Q000627:therapeutic use; D004802:Eosinophilia / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D005500:Follow-Up Studies; D006801:Humans; D008297:Male; D000076322:Multimorbidity; D010996:Pleural Effusion / Q000139:chemically induced* / Q000175:diagnosis / Q000628:therapy; D012720:Severity of Illness Index; D013906:Thoracoscopy / Q000379:methods; D020246:Venous Thrombosis / Q000188:drug therapy* / Q000517:prevention & control
chemical_list: D000069604:Dabigatran
keywords: dabigatran; effusion; eosinophilia; pleura; thoracoscopy