title: Strongyloides stercoralis Infection Causing Obstructive Jaundice and Refractory Pancreatitis: A Lesson Learned from a Case Study.
abstract: A 58-year-old Japanese woman came to our institution because of leg edema and abdominal distention. She had developed acute pancreatitis 5 times in the past 3 years. Dilation of the bile duct and main pancreatic duct without obstruction was observed on computed tomography and magnetic resonance cholangiopancreatography. The presence of Strongyloides stercoralis was highly suspected from the biopsy sample from the duodenal papilla. Polymerase chain reaction amplification and sequencing of small subunit rDNA from paraffin-embedded specimens identified the worm as S. stercoralis. All of the symptoms were considered to be associated with S. stercoralis infection. Therefore, the patient was treated with oral administration of ivermectin. Subsequently, symptoms and laboratory data improved. There has been no recurrence of the symptoms to date.
authors.affiliation: Department of Gastroenterology and Hepatology, Tokyo Medical University, Japan.
authors.forename: Nobuhito
authors.initials: N
authors.lastname: Ikeuchi
authors.forename: Takao
authors.initials: T
authors.lastname: Itoi
authors.forename: Ryosuke
authors.initials: R
authors.lastname: Tonozuka
authors.forename: Shuntaro
authors.initials: S
authors.lastname: Mukai
authors.forename: Yohei
authors.initials: Y
authors.lastname: Koyama
authors.forename: Takayoshi
authors.initials: T
authors.lastname: Tsuchiya
authors.forename: Tetsuya
authors.initials: T
authors.lastname: Matsumoto
authors.forename: Yasutaka
authors.initials: Y
authors.lastname: Mizuno
authors.forename: Itaru
authors.initials: I
authors.lastname: Nakamura
authors.forename: Akina
authors.initials: A
authors.lastname: Hino
authors.forename: Fuminori
authors.initials: F
authors.lastname: Moriyasu
mesh_terms: D000818:Animals; D000977:Antiparasitic Agents / Q000008:administration & dosage; D002779:Cholestasis / Q000175:diagnosis / Q000469:parasitology; D005260:Female; D006801:Humans; D007559:Ivermectin / Q000627:therapeutic use; D041781:Jaundice, Obstructive / Q000188:drug therapy / Q000469:parasitology*; D008875:Middle Aged; D010195:Pancreatitis / Q000188:drug therapy / Q000469:parasitology*; D017171:Strongyloides stercoralis / Q000302:isolation & purification; D013322:Strongyloidiasis / Q000175:diagnosis* / Q000188:drug therapy / Q000469:parasitology*
chemical_list: D000977:Antiparasitic Agents; D007559:Ivermectin