title: Medical abortion in women with large uterine fibroids: a case series.
abstract: Women with fibroid uteri seeking surgical abortion often represent a unique challenge. When the uterine cavity is significantly enlarged or distorted making surgical evacuation difficult or impossible, we offer medical abortion using mifepristone followed by misoprostol beyond the standard 63- to 70-day gestational age cutoff that is typically recommended. This case series describes our regimen and outcomes for 6 patients from 10 to 13 weeks gestation underdoing outpatient medical abortion and 6 patients from 14 to 20 weeks gestation undergoing inpatient medical abortion. Three patients required evacuation for retained products and all others had successful medical abortions without complications.
authors.affiliation: University of Maryland School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, MD 21201, USA. Electronic address: kmark@fpi.umaryland.edu.
authors.forename: Katrina
authors.initials: K
authors.lastname: Mark
authors.affiliation: University of Maryland School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, MD 21201, USA.
authors.forename: Barbara
authors.initials: B
authors.lastname: Bragg
authors.affiliation: University of Maryland School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, MD 21201, USA.
authors.forename: Kiranpreet
authors.initials: K
authors.lastname: Chawla
authors.affiliation: University of Maryland School of Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, MD 21201, USA.
authors.forename: Katherine
authors.initials: K
authors.lastname: Hladky
mesh_terms: D000019:Abortifacient Agents / Q000008:administration & dosage*; D000028:Abortion, Induced; D000282:Administration, Intravaginal; D000328:Adult; D004334:Drug Administration Schedule; D005260:Female; D005865:Gestational Age; D006801:Humans; D007889:Leiomyoma / Q000150:complications*; D008396:Maryland; D015735:Mifepristone / Q000008:administration & dosage; D016595:Misoprostol / Q000008:administration & dosage; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000188:drug therapy*; D011261:Pregnancy Trimester, First; D011262:Pregnancy Trimester, Second; D014594:Uterine Neoplasms / Q000150:complications*
chemical_list: D000019:Abortifacient Agents; D016595:Misoprostol; D015735:Mifepristone
keywords: Abortion; Fibroid; Leiomyoma; Mifepristone; Misoprostol