title: Enantioseparations in open-tubular capillary electrochromatography: Recent advances and applications.
abstract: This review highlights recent advances and applications in open-tubular capillary electrochromatography (OT-CEC) for enantioseparations during the last decade. Although extensive research has been conducted in the area of separations by use of CEC, and a big number of reviews have been published, there is not a review on exclusively the use of chiral stationary phases (CSPs) in OT-CEC for enantioseparations. Therefore, in this review, the design and synthesis of different CSPs are presented, and their potential applications in OT-CEC for enantioseparations are discussed. The different approaches to CSP development include chiral nanomaterials, porous layers, molecular imprinting, sol-gel technique, polyelectrolyte multilayer coating, polymeric coating and others.
authors.affiliation: Department of Chemistry, University of Cyprus, 1678 Nicosia, Cyprus. Electronic address: ckapni1@ucy.ac.cy.
authors.forename: Constantina P
authors.initials: CP
authors.lastname: Kapnissi-Christodoulou
authors.affiliation: Department of Chemistry, University of Cyprus, 1678 Nicosia, Cyprus.
authors.forename: Athina G
authors.initials: AG
authors.lastname: Nicolaou
authors.affiliation: Department of Chemistry, University of Cyprus, 1678 Nicosia, Cyprus.
authors.forename: Ioannis J
authors.initials: IJ
authors.lastname: Stavrou
mesh_terms: D053801:Capillary Electrochromatography / Q000639:trends*; D011108:Polymers / Q000737:chemistry
chemical_list: D011108:Polymers
keywords: Chiral coating; Chiral selector; Chiral stationary phases; Enantioseparations; Open-tubular capillary electrochromatography; Review