title: Mumps Outbreak at a University and Recommendation for a Third Dose of Measles-Mumps-Rubella Vaccine - Illinois, 2015-2016.
abstract: Mumps is an acute viral disease characterized by fever and swelling of the parotid or other salivary glands. On May 1, 2015, the Illinois Department of Public Health (IDPH) confirmed a mumps outbreak at the University of Illinois at Urbana-Champaign. IDPH and the Champaign-Urbana Public Health District (C-UPHD) conducted an investigation and identified 317 cases of mumps during April 2015-May 2016. Because of sustained transmission in a population with high 2-dose coverage with measles-mumps-rubella (MMR) vaccine, a third MMR dose was recommended by IDPH, C-UPHD, and the university's McKinley Health Center. No formal recommendation for or against the use of a third MMR dose has been issued by the Advisory Committee on Immunization Practices (ACIP) (1). However, CDC has provided guidelines for use of a third dose as a control measure during mumps outbreaks in settings in which persons are in close contact with one another, where transmission is sustained despite high 2-dose MMR coverage, and when traditional control measures fail to slow transmission (2).
authors.forename: Justin P
authors.initials: JP
authors.lastname: Albertson
authors.forename: Whitney J
authors.initials: WJ
authors.lastname: Clegg
authors.forename: Heather D
authors.initials: HD
authors.lastname: Reid
authors.forename: Benjamin S
authors.initials: BS
authors.lastname: Arbise
authors.forename: Julie
authors.initials: J
authors.lastname: Pryde
authors.forename: Awais
authors.initials: A
authors.lastname: Vaid
authors.forename: Rachella
authors.initials: R
authors.lastname: Thompson-Brown
authors.forename: Fredrick
authors.initials: F
authors.lastname: Echols
mesh_terms: D000293:Adolescent; D000328:Adult; D002487:Centers for Disease Control and Prevention, U.S.; D004196:Disease Outbreaks / Q000517:prevention & control*; D005260:Female; D006801:Humans; D007087:Illinois / Q000453:epidemiology; D007115:Immunization Schedule; D008297:Male; D022542:Measles-Mumps-Rubella Vaccine / Q000008:administration & dosage*; D008875:Middle Aged; D009107:Mumps / Q000453:epidemiology* / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D014481:United States; D014495:Universities; D055815:Young Adult
chemical_list: D022542:Measles-Mumps-Rubella Vaccine