title: Graphene-doped Bi2S3 nanorods as visible-light photoelectrochemical aptasensing platform for sulfadimethoxine detection.
abstract: Bismuth sulphide (Bi2S3) nanorods doped with graphene (G) were synthesized and explored as photoactive materials for constructing a photoelectrochemical (PEC) aptasensor for sulfadimethoxine (SDM) detection. The formation of Bi2S3 nanorods and G nanosheets was observed by scanning electron microscopy (SEM) and further characterized by X-ray diffraction (XRD) spectroscopy. The PEC measurements indicated that the photocurrent response of Bi2S3 was obviously improved by doping suitable amount of G. The G-Bi2S3 composite coated electrode was utilized for fabricating a PEC aptasensor by covalently immobilizing a 5'-amino-terminated SDM aptamer on the electrode surface. Based on the specific interaction between SDM and the aptamer, a PEC sensor responsive to SDM was obtained. Under optimal conditions, the proposed sensor showed a linear photocurrent response to SDM in the concentration range of 1.0-100nM, with a low detection limit (3S/N) of 0.55nM. Moreover, the sensor showed high sensitivity, stability and reproducibility. The potential applicability of the PEC aptasensor was confirmed by detecting SDM in veterinary drug formulation and milk.
authors.affiliation: Key laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, Wuhan, 430074 PR China.
authors.forename: Otieno Kevin
authors.initials: OK
authors.lastname: Okoth
authors.affiliation: Key laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, Wuhan, 430074 PR China.
authors.forename: Kai
authors.initials: K
authors.lastname: Yan
authors.affiliation: Key laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, Wuhan, 430074 PR China.
authors.forename: Yong
authors.initials: Y
authors.lastname: Liu
authors.affiliation: Key laboratory of Material Chemistry for Energy Conversion and Storage (Ministry of Education), School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Luoyu Road 1037, Wuhan, 430074 PR China. Electronic address: zhangjd@mail.hust.edu.cn.
authors.forename: Jingdong
authors.initials: J
authors.lastname: Zhang
mesh_terms: D000890:Anti-Infective Agents / Q000032:analysis; D052157:Aptamers, Nucleotide / Q000737:chemistry*; D001729:Bismuth / Q000737:chemistry*; D003217:Conductometry / Q000295:instrumentation*; D004784:Environmental Monitoring / Q000295:instrumentation; D004785:Environmental Pollutants / Q000032:analysis; D004867:Equipment Design; D019544:Equipment Failure Analysis; D006108:Graphite / Q000737:chemistry; D008027:Light; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D010783:Photometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity; D013412:Sulfadimethoxine / Q000032:analysis* / Q000528:radiation effects; D013440:Sulfides / Q000737:chemistry*; D019155:Veterinary Drugs / Q000032:analysis
chemical_list: D000890:Anti-Infective Agents; D052157:Aptamers, Nucleotide; D004785:Environmental Pollutants; D013440:Sulfides; D019155:Veterinary Drugs; D013412:Sulfadimethoxine; D006108:Graphite; D001729:Bismuth; C049897:bismuth sulfide
keywords: Aptamer; Bismuth sulphide; Graphene; Photoelectrochemical sensor; Sulfadimethoxine