title: Insights into Population Health Management Through Disease Diagnoses Networks.
abstract: The increasing availability of electronic health care records has provided remarkable progress in the field of population health. In particular the identification of disease risk factors has flourished under the surge of available data. Researchers can now access patient data across a broad range of demographics and geographic locations. Utilizing this Big healthcare data researchers have been able to empirically identify specific high-risk conditions found within differing populations. However to date the majority of studies approached the issue from the top down, focusing on the prevalence of specific diseases within a population. Through our work we demonstrate the power of addressing this issue bottom-up by identifying specifically which diseases are higher-risk for a specific population. In this work we demonstrate that network-based analysis can present a foundation to identify pairs of diagnoses that differentiate across population segments. We provide a case study highlighting differences between high and low income individuals in the United States. This work is particularly valuable when addressing population health management within resource-constrained environments such as community health programs where it can be used to provide insight and resource planning into targeted care for the population served.
authors.affiliation: University of Notre Dame, Computer Science and Engineering, Notre Dame, 46556, USA.|University of Notre Dame, Interdisciplinary Center for Network Science and Applications (iCeNSA), Notre Dame, 46556, USA.
authors.forename: Keith
authors.initials: K
authors.lastname: Feldman
authors.affiliation: University of Maribor, Health Sciences, Maribor, 2000, Slovenia.|University of Maribor, Electrical Engineering and Computer Science, Maribor, 2000, Slovenia.
authors.forename: Gregor
authors.initials: G
authors.lastname: Stiglic
authors.affiliation: University of Notre Dame, Computer Science and Engineering, Notre Dame, 46556, USA.|University of Notre Dame, Interdisciplinary Center for Network Science and Applications (iCeNSA), Notre Dame, 46556, USA.
authors.forename: Dipanwita
authors.initials: D
authors.lastname: Dasgupta
authors.affiliation: St. Joseph's Regional Medical Center, Mishawaka, 46544, USA.
authors.forename: Mark
authors.initials: M
authors.lastname: Kricheff
authors.affiliation: Temple University, Data Analytics and Biomedical Informatics Center, Philadelphia, 19122, USA.
authors.forename: Zoran
authors.initials: Z
authors.lastname: Obradovic
authors.affiliation: University of Notre Dame, Computer Science and Engineering, Notre Dame, 46556, USA.|University of Notre Dame, Interdisciplinary Center for Network Science and Applications (iCeNSA), Notre Dame, 46556, USA.|Wroclaw University of Technology, Wrocław, 50-370, Poland.
authors.forename: Nitesh V
authors.initials: NV
authors.lastname: Chawla
mesh_terms: D015897:Comorbidity; D004194:Disease; D006801:Humans; D007182:Income; D000075485:Population Health