title: Fluid Dynamics in Rotary Piston Blood Pumps.
abstract: Mechanical circulatory support can maintain a sufficient blood circulation if the native heart is failing. The first implantable devices were displacement pumps with membranes. They were able to provide a sufficient blood flow, yet, were limited because of size and low durability. Rotary pumps have resolved these technical drawbacks, enabled a growing number of mechanical circulatory support therapy and a safer application. However, clinical complications like gastrointestinal bleeding, aortic insufficiency, thromboembolic complications, and impaired renal function are observed with their application. This is traced back to their working principle with attenuated or non-pulsatile flow and high shear stress. Rotary piston pumps potentially merge the benefits of available pump types and seem to avoid their complications. However, a profound assessment and their development requires the knowledge of the flow characteristics. This study aimed at their investigation. A functional model was manufactured and investigated with particle image velocimetry. Furthermore, a fluid-structure interaction computational simulation was established to extend the laboratory capabilities. The numerical results precisely converged with the laboratory measurements. Thus, the in silico model enabled the investigation of relevant areas like gap flows that were hardly feasible with laboratory means. Moreover, an economic method for the investigation of design variations was established.
authors.affiliation: Institute of Applied Medical Engineering, Helmholtz-Institute RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany. wappenschmidt@ame.rwth-aachen.de.|Department of Thoracic and Cardiovascular Surgery, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074, Aachen, Germany. wappenschmidt@ame.rwth-aachen.de.
authors.forename: Johannes
authors.identifier: 0000-0003-0463-4767
authors.initials: J
authors.lastname: Wappenschmidt
authors.affiliation: Institute of Applied Medical Engineering, Helmholtz-Institute RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany.
authors.forename: Simon J
authors.initials: SJ
authors.lastname: Sonntag
authors.affiliation: Institute of Applied Medical Engineering, Helmholtz-Institute RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany.
authors.forename: Martin
authors.initials: M
authors.lastname: Buesen
authors.affiliation: Institute of Applied Medical Engineering, Helmholtz-Institute RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany.
authors.forename: Sascha
authors.initials: S
authors.lastname: Gross-Hardt
authors.affiliation: Institute of Applied Medical Engineering, Helmholtz-Institute RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany.
authors.forename: Tim
authors.initials: T
authors.lastname: Kaufmann
authors.affiliation: Institute of Applied Medical Engineering, Helmholtz-Institute RWTH Aachen University, Pauwelsstraße 20, 52074, Aachen, Germany.
authors.forename: Thomas
authors.initials: T
authors.lastname: Schmitz-Rode
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074, Aachen, Germany.
authors.forename: Ruediger
authors.initials: R
authors.lastname: Autschbach
authors.affiliation: Department of Thoracic and Cardiovascular Surgery, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074, Aachen, Germany.
authors.forename: Andreas
authors.initials: A
authors.lastname: Goetzenich
mesh_terms: D007260:Infusion Pumps; D008962:Models, Theoretical; D012212:Rheology
keywords: Immersed boundary method; Mechanical circulatory support; Particle image velocimetry; Rotary blood pump; SCARABAEUS; Wankel engine