title: Pediatric Miller Fisher Syndrome Complicating an Epstein-Barr Virus Infection.
abstract: Miller Fisher syndrome, a variant of Guillain-Barré syndrome, is an acute inflammatory demyelinating polyradiculoneuropathy that may occur weeks after a bacterial or viral infection. Campylobacter jejuni and Haemophilus influenzae are frequently reported etiological agents.
  
  
  
  We describe a boy with Miller Fisher syndrome following Epstein-002DBarr virus primary infectious mononucleosis. He presented with bilateral dysfunction of several cranial nerves and hyporeflexia of the limbs but without ataxia. Miller Fisher syndrome was confirmed by the presence of anti-GQ1b antibodies in a blood sample. Epstein-Barr virus was identified by polymerase chain reaction and serology.
  
  
  
  Epstein-Barr virus should be considered as a Miller Fisher syndrome's causative agent. The physiopathology of this condition may involve cross-reactive T-cells against Epstein-Barr virus antigens and gangliosides.
authors.affiliation: Department of Paediatrics, Nîmes University Hospital, Nîmes, France.
authors.forename: Céline
authors.initials: C
authors.lastname: Communal
authors.affiliation: Department of Paediatrics, Nîmes University Hospital, Nîmes, France; INSERM U 1183, Montpellier-Nîmes University, Nîmes, France. Electronic address: anne.filleron@chu-nimes.fr.
authors.forename: Anne
authors.initials: A
authors.lastname: Filleron
authors.affiliation: Department of Paediatrics, Nîmes University Hospital, Nîmes, France.
authors.forename: Sandrine
authors.initials: S
authors.lastname: Baron-Joly
authors.affiliation: Department of Paediatrics, Nîmes University Hospital, Nîmes, France.
authors.forename: Randa
authors.initials: R
authors.lastname: Salet
authors.affiliation: Department of Paediatrics, Nîmes University Hospital, Nîmes, France; INSERM U 1183, Montpellier-Nîmes University, Nîmes, France.
authors.forename: Tu-Anh
authors.initials: TA
authors.lastname: Tran
mesh_terms: D000293:Adolescent; D020031:Epstein-Barr Virus Infections / Q000097:blood / Q000150:complications* / Q000175:diagnosis*; D006801:Humans; D008297:Male; D019846:Miller Fisher Syndrome / Q000097:blood / Q000175:diagnosis* / Q000209:etiology*
keywords: Epstein-Barr virus; Guillain-Barré syndrome; Infectious mononucleosis; Miller-Fisher syndrome; pediatric; polyneuropathy