title: The Management of Relapsed and Refractory Acute Myeloid Leukaemia in Adults.
abstract: The improved survival of patients with AML over the last 20-30 years can be attributed both to advances in cytotoxic therapy and in supportive care and up to 25% of responders may be cured. Nevertheless, most patients with AML eventually relapse and ultimately die from resistant leukaemia and up to 30% fail to attain initial complete remission (CR). This annotation reviews current therapeutic options in relapsed and refractory AML in adults.
authors.affiliation: a Department of Haematology, The Royal London Hospital, Whitechapel, London, UK.
authors.forename: L
authors.initials: L
authors.lastname: Jones
authors.affiliation: a Department of Haematology, The Royal London Hospital, Whitechapel, London, UK.
authors.forename: A C
authors.initials: AC
authors.lastname: Newland
keywords: Acute myeloid leukaemia; refractory; relapsed