title: Renal Function Predicts Outcomes in Patients with Ischaemic Stroke and Haemorrhagic Stroke.
abstract: OBJECTIVE
  We evaluated renal function and the impact of renal function on in-hospital outcomes in patients with ischaemic and haemorrhagic stroke.
  
  
  METHODS
  We collected data from 766 patients with stroke; 637 (83.2 %) with ischaemic and 129 with haemorrhagic one.
  
  
  RESULTS
  The mean serum creatinine on admission in patients with both types of stroke, who died, was significantly higher than in those who survived. Multivariate analysis showed that independent predictors of mortality in patients with ischaemic stroke were: ischemic heart disease or prior myocardial infarction, diabetes, admission glucose and eGFR on admission. Also, multivariate analysis showed that independent predictors of mortality in patients with haemorrhagic stroke were: age and admission glucose.
  
  
  CONCLUSIONS
  Patients with haemorrhagic stroke, in particular with acute kidney injury during hospitalisation had significantly worse outcomes than patients with ischaemic stroke. Assessment of kidney function is prerequisite to employ the necessary measures to decrease the risk of in-hospital mortality among patients with acute stroke. Appropriate approach to patients with renal dysfunction (adequate hydration, avoidance of nephrotoxic drugs, drug dose adjustment etc) should be considered as preventive and therapeutic strategies in the management of acute stroke.
authors.affiliation: Department of Clinical Medicine, Medical University of Bialystok, Bialystok, Poland.
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Snarska
authors.forename: Katarzyna
authors.initials: K
authors.lastname: Kapica-Topczewska
authors.forename: Hanna
authors.initials: H
authors.lastname: Bachórzewska-Gajewska
authors.forename: Jolanta
authors.initials: J
authors.lastname: Małyszko
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D002545:Brain Ischemia / Q000401:mortality*; D002543:Cerebral Hemorrhage / Q000401:mortality*; D019468:Disease Management; D005260:Female; D005919:Glomerular Filtration Rate; D006801:Humans; D007674:Kidney Diseases / Q000175:diagnosis; D007677:Kidney Function Tests; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D020521:Stroke / Q000175:diagnosis / Q000401:mortality* / Q000517:prevention & control; D016896:Treatment Outcome