title: Gender differences in knee abduction during weight-bearing activities: A systematic review and meta-analysis.
abstract: Increased knee abduction during weight-bearing activities is suggested to be a contributing factor for the high knee injury risk reported in women. However, studies investigating gender difference in knee abduction are inconclusive.
  
  
  
  To systematically review gender-differences in knee abduction during weight-bearing activities in individuals with or without knee injury.
  
  
  
  A systematic review and meta-analysis were conducted according to the PRISMA guidelines. A search in the databases Medline, CINAHL and EMBASE was performed until September 2015. Inclusion criteria were studies that reported (1) gender differences, (2) healthy individuals and/or those with anterior cruciate ligament (ACL) deficiency or reconstruction or patellofemoral pain PFP, and (3) knee abduction assessed with either motion analysis or visual observation during weight-bearing activity.
  
  
  
  Fifty-eight articles met the inclusion criteria. Women with PFP had greater peak knee abduction compared to men (Std diff in mean; -1.34, 95%CI; -1.83 to -0.84). In healthy individuals, women performed weight-bearing tasks with greater knee abduction throughout the movement (initial contact, peak abduction, excursion) (Std diff in mean; -0.68 to -0.79, 95%CI; -1.04 to -0.37). In subgroup analyses by task, differences in knee abduction between genders were present for most tasks, including running, jump landings and cutting movements. There were too few studies in individuals with ACL injury to perform meta-analysis.
  
  
  
  The gender difference in knee abduction during weight-bearing activities should be considered in training programs aimed at preventing or treating knee injury.
authors.affiliation: Department of Health Sciences, Lund University, Lund, Sweden. Electronic address: anna.cronstrom@gmail.com.
authors.forename: Anna
authors.initials: A
authors.lastname: Cronström
authors.affiliation: School of Exercise Science, Australian Catholic University, Brisbane, Australia. Electronic address: mark.creaby@acu.edu.au.
authors.forename: Mark W
authors.initials: MW
authors.lastname: Creaby
authors.affiliation: Department of Health Sciences, Lund University, Lund, Sweden. Electronic address: jenny.almqvist@med.lu.se.
authors.forename: Jenny
authors.initials: J
authors.lastname: Nae
authors.affiliation: Department of Health Sciences, Lund University, Lund, Sweden. Electronic address: eva.ageberg@med.lu.se.
authors.forename: Eva
authors.initials: E
authors.lastname: Ageberg
mesh_terms: D016118:Anterior Cruciate Ligament / Q000503:physiopathology*; D000070598:Anterior Cruciate Ligament Injuries / Q000453:epidemiology / Q000503:physiopathology / Q000534:rehabilitation; D001696:Biomechanical Phenomena; D005260:Female; D014943:Global Health; D006801:Humans; D015994:Incidence; D007717:Knee / Q000503:physiopathology*; D007719:Knee Joint; D008297:Male; D009068:Movement; D012737:Sex Factors; D013177:Sports; D016474:Weight-Bearing / Q000502:physiology*
keywords: ACL injury; Functional performance; Knee abduction; Knee valgus; Patellofemoral pain; Prevention