title: Study of Antimicrobial and Cytotoxic Potential of the Oyster Mushroom Pleurotus ostreatus cv. Florida (Agaricomycetes).
abstract: This work was undertaken to evaluate in vitro antimicrobial and cytotoxic potential of Pleurotus ostreatus cv. Florida. Mushroom basidiocarps were extracted in water:ethanol (1:1, v/v), and the resulting extract was subjected to antimicrobial studies against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Klebsiella oxytoca, Bacillus subtilis, and Candida albicans. Cytotoxic potential on viable human leukocytes was studied. In vitro results showed excellent antimicrobial and cytotoxic potentials of the mushroom extract. Thus, functional properties of P. ostreatus cv. Florida could be used in the search for novel therapeutics.
authors.affiliation: Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, M.P., India.
authors.forename: Aditya
authors.initials: A
authors.lastname: Ganeshpurkar
authors.affiliation: Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, M.P., India; Sun Institute of Pharmaceutical Education and Research, Bhind, M.P., India.
authors.forename: Santosh Singh
authors.initials: SS
authors.lastname: Bhadoriya
authors.affiliation: Drug Discovery Laboratory, Shri Ram Institute of Technology-Pharmacy, Jabalpur, M.P., India.
authors.forename: Priya
authors.initials: P
authors.lastname: Pardhi
authors.affiliation: Department of Pharmacy, Guru Ramdas Khalsa Institute of Science & Technology, Jabalpur, M.P., India.
authors.forename: Alok Pal
authors.initials: AP
authors.lastname: Jain
authors.affiliation: Department of Pharmacy, Guru Ramdas Khalsa Institute of Science & Technology, Jabalpur, M.P., India.
authors.forename: Gopal
authors.initials: G
authors.lastname: Rai
mesh_terms: D000890:Anti-Infective Agents / Q000494:pharmacology*; D001412:Bacillus subtilis / Q000187:drug effects; D002176:Candida albicans / Q000187:drug effects; D045424:Complex Mixtures / Q000494:pharmacology*; D003603:Cytotoxins / Q000494:pharmacology*; D004926:Escherichia coli / Q000187:drug effects; D048690:Fruiting Bodies, Fungal / Q000737:chemistry; D007709:Klebsiella / Q000187:drug effects; D020076:Pleurotus / Q000737:chemistry*; D013211:Staphylococcus aureus / Q000187:drug effects
chemical_list: D000890:Anti-Infective Agents; D045424:Complex Mixtures; D003603:Cytotoxins