title: Burkitt Lymphoma Presenting as an Intracardiac Mass: Case Report and Review of Literature.
abstract: BACKGROUND Non-neoplastic causes such as infections and thrombi account for most intracardiac masses. Primary tumors such as myxomas and metastasis from breast cancer, lung cancer, or melanomas account for many of the remaining cases. Burkitt lymphoma manifesting as an intracardiac mass is a rare entity, with 21 cases reported in the English literature. CASE REPORT We report the case of a man infected with human immunodeficiency virus (HIV) who presented with non-specific cardiac symptoms and was later found to have intracardiac mass caused by Burkitt lymphoma. His rapid decline with unexpected complications was reversed with prompt management. Subsequent to induction, the patient achieved a near complete response with considerable improvement in his condition. CONCLUSIONS Lymphoma should be considered in the differential diagnosis of intracardiac masses. Associated cardiac symptoms are frequently non-specific and can often be overlooked or underappreciated. Burkitt lymphoma has a short doubling time and an intracardiac lesion can become life-threatening in a matter of days. Early recognition and prompt treatment are crucial to achieving optimal outcomes.
authors.affiliation: Department of Medicine, University of Arizona, Banner University Medical Center, Tucson, AZ, USA.
authors.forename: Onyee
authors.initials: O
authors.lastname: Chan
authors.affiliation: Department of Medicine, Maricopa Integrated Health System, Phoenix, AZ, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Igwe
authors.affiliation: Department of Cardiology, Maricopa Integrated Health System, Phoenix, AZ, USA.
authors.forename: Christian S
authors.initials: CS
authors.lastname: Breburda
authors.affiliation: Department of Hematology Oncology, Maricopa Integrated Health System, Phoenix, AZ, USA.
authors.forename: Surabhi
authors.initials: S
authors.lastname: Amar
mesh_terms: D000328:Adult; D002051:Burkitt Lymphoma / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D019560:Echocardiography, Three-Dimensional; D015658:HIV Infections / Q000150:complications; D006338:Heart Neoplasms / Q000150:complications / Q000000981:diagnostic imaging* / Q000628:therapy; D006801:Humans; D008297:Male; D014057:Tomography, X-Ray Computed