title: Validation of the Singapore nomogram for outcome prediction in breast phyllodes tumours: an Australian cohort.
abstract: OBJECTIVE
  To validate the utility of the Singapore nomogram for outcome prediction in breast phyllodes tumours.
  
  
  METHODS
  Histological parameters, surgical margin status and clinical follow-up data of 34 women diagnosed with phyllodes tumours were analysed. Biostatistics modelling was performed, and the concordance between predicted and observed survivals was calculated.
  
  
  RESULTS
  Women with a high nomogram score had an increased risk of developing relapse, which was predicted using the parameters defined by the Singapore nomogram.
  
  
  CONCLUSIONS
  The Singapore nomogram is useful in predicting outcome in breast phyllodes tumours when applied to an Australian cohort of 34 women.
authors.affiliation: Department of Anatomical Pathology, Singapore General Hospital, Singapore.
authors.forename: Tze Wei
authors.initials: TW
authors.lastname: Chng
authors.affiliation: School of Health and Science, Western Sydney University, Western Sydney, Australia.
authors.forename: Jonathan Y H
authors.initials: JY
authors.lastname: Lee
authors.affiliation: Discipline of Pathology, School of Medicine, Western Sydney University; Cancer Pathology, Bosch Institute, University of Sydney; Ingham Institute for Applied Medical Research, and South Western Sydney Clinical School, UNSW, Liverpool, New South Wales, Australia.
authors.forename: C Soon
authors.initials: CS
authors.lastname: Lee
authors.affiliation: Division of Medicine, Singapore General Hospital, Singapore.
authors.forename: HuiHua
authors.initials: H
authors.lastname: Li
authors.affiliation: Division of Biodevices and Diagnostics, Institute of Bioengineering and Nanotechnology, Singapore.
authors.forename: Min-Han
authors.initials: MH
authors.lastname: Tan
authors.affiliation: Division of Pathology, Singapore General Hospital, Singapore.
authors.forename: Puay Hoon
authors.initials: PH
authors.lastname: Tan
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D056808:Biostatistics; D001940:Breast / Q000473:pathology; D001943:Breast Neoplasms / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D015331:Cohort Studies; D018572:Disease-Free Survival; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000401:mortality; D009517:New South Wales / Q000453:epidemiology; D049451:Nomograms; D003557:Phyllodes Tumor / Q000175:diagnosis* / Q000401:mortality / Q000601:surgery; D012306:Risk; D012846:Singapore / Q000453:epidemiology; D016896:Treatment Outcome
keywords: BREAST PATHOLOGY; DIAGNOSTICS; NEOPLASMS