title: Viral RNA in Blood as Indicator of Severe Outcome in Middle East Respiratory Syndrome Coronavirus Infection.
abstract: We evaluated the diagnostic and clinical usefulness of blood specimens to detect Middle East respiratory syndrome coronavirus infection in 21 patients from the 2015 outbreak in South Korea. Viral RNA was detected in blood from 33% of patients at initial diagnosis, and the detection preceded a worse clinical course.
authors.forename: So Yeon
authors.initials: SY
authors.lastname: Kim
authors.forename: Sun Jae
authors.initials: SJ
authors.lastname: Park
authors.forename: Sook Young
authors.initials: SY
authors.lastname: Cho
authors.forename: Ran-Hui
authors.initials: RH
authors.lastname: Cha
authors.forename: Hyeon-Gun
authors.initials: HG
authors.lastname: Jee
authors.forename: Gayeon
authors.initials: G
authors.lastname: Kim
authors.forename: Hyoung-Shik
authors.initials: HS
authors.lastname: Shin
authors.forename: Yeonjae
authors.initials: Y
authors.lastname: Kim
authors.forename: Yu Mi
authors.initials: YM
authors.lastname: Jung
authors.forename: Jeong-Sun
authors.initials: JS
authors.lastname: Yang
authors.forename: Sung Soon
authors.initials: SS
authors.lastname: Kim
authors.forename: Sung Im
authors.initials: SI
authors.lastname: Cho
authors.forename: Man Jin
authors.initials: MJ
authors.lastname: Kim
authors.forename: Jee-Soo
authors.initials: JS
authors.lastname: Lee
authors.forename: Seung Jun
authors.initials: SJ
authors.lastname: Lee
authors.forename: Soo Hyun
authors.initials: SH
authors.lastname: Seo
authors.forename: Sung Sup
authors.initials: SS
authors.lastname: Park
authors.forename: Moon-Woo
authors.initials: MW
authors.lastname: Seong
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D018352:Coronavirus Infections / Q000097:blood* / Q000175:diagnosis / Q000453:epidemiology / Q000821:virology; D004196:Disease Outbreaks; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D065207:Middle East Respiratory Syndrome Coronavirus / Q000235:genetics; D063868:Patient Outcome Assessment; D011379:Prognosis; D012367:RNA, Viral / Q000097:blood*; D056910:Republic of Korea / Q000453:epidemiology; D055815:Young Adult
chemical_list: D012367:RNA, Viral
keywords: MERS-CoV; Middle East respiratory syndrome; blood; coronavirus; prognosis; real-time PCR; viruses; zoonoses