title: Outcome Analysis of Day-3 Frozen Embryo Transfer v/s Fresh Embryo Transfer in Infertility: A Prospective Therapeutic Study in Indian Scenario.
abstract: BACKGROUND
  Advanced fertilization techniques like frozen embryo transfer (FET) and assisted reproductive technology have become popular and commonly used methods to treat patients suffering from infertility. Incidences of infertility are on a rise due to increased representation of females in the work place, delay in marriages, stress, and ignorance.
  
  
  METHODS
  We performed this prospective therapeutic study to compare FET and fresh embryo transfer in the treatment of infertility in terms of conception rate, patient acceptance, complications, and patient's compliance. A prospective screening therapeutic study on 108 patients, from September 2013 to September 2014 in Karnataka, India, randomized the patients into 2 groups (n = 54), Group-I treated with day-3 FET while Group-II was treated with fresh embryo transfer, after performing ICSI.
  
  
  RESULTS
  In 108 patients, 45 % patients were within 35 years of age, 35 % were in the age group 35-39. Significantly, 22 (40.75 %) patients treated with FET conceived (P = 0.022), whereas 16 (29.63 %) patients treated with fresh embryo transfer conceived (P = 0.59).
  
  
  CONCLUSIONS
  There is limited published literature from the subcontinent, comparing techniques like FET and embryo transfers in the treatment of infertility. Awareness and economic reforms must be formulated in India to facilitate individuals facing infertility problems to conceive.
  
  
  CONCLUSIONS
  FET has better and significant conception rates compared to fresh embryo transfers. FET shares an advantage of providing good quality embryos for future and subsequent implantations in cases of failure. Patient counseling and motivation play a pivotal role in the success of therapeutic procedure.
authors.affiliation: Radhakrishna Multispecialty Hospital and IVF Center, Sunrise Tower, Girinagar, Bengaluru, 560085 India.
authors.forename: Neha Palo
authors.initials: NP
authors.lastname: Chandel
authors.affiliation: Radhakrishna Multispecialty Hospital and IVF Center, Sunrise Tower, Girinagar, Bengaluru, 560085 India.
authors.forename: Vidya V
authors.initials: VV
authors.lastname: Bhat
authors.affiliation: Radhakrishna Multispecialty Hospital and IVF Center, Sunrise Tower, Girinagar, Bengaluru, 560085 India.
authors.forename: B S
authors.initials: BS
authors.lastname: Bhat
authors.affiliation: JLN Hospital and Research Center, Bhilai, Chhattisgarh India.
authors.forename: Sidharth S
authors.initials: SS
authors.lastname: Chandel
keywords: ART; Family; Frozen embryo transfer; India; Infertility; Reproduction