title: Discovery of a Potent and Selective Hetero-Bivalent AChE Inhibitor via Bioisosteric Replacement.
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230.
authors.forename: Orazio
authors.initials: O
authors.lastname: Nicolotti
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230.
authors.forename: Leonardo
authors.initials: L
authors.lastname: Pisani
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230.
authors.forename: Marco
authors.initials: M
authors.lastname: Catto
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230.
authors.forename: Francesco
authors.initials: F
authors.lastname: Leonetti
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230.
authors.forename: Ilenia
authors.initials: I
authors.lastname: Giangreco
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230.
authors.forename: Angela
authors.initials: A
authors.lastname: Stefanachi
authors.affiliation: Dipartimento Farmaco-Chimico, Università degli Studi di Bari "Aldo Moro"via Orabona 4, 70125 Bari, Italy tel.: +39 080 5442782; fax: +39 080 5442230. carotti@farmchim.uniba.it.
authors.forename: Angelo
authors.initials: A
authors.lastname: Carotti
keywords: Alzheimer’s disease; Bioisosteric replacement; Dual binding site AChE inhibitors; Selective hetero-bivalent acetylcholinesterase inhibitors