title: Vaccine hesitancy among general practitioners: evaluation and comparison of their immunisation practice for themselves, their patients and their children.
abstract: To gain knowledge about vaccine hesitancy among general practitioners (GPs), we conducted a survey to compare their vaccination attitudes for themselves, their children and their patients. A questionnaire survey was sent to GPs working in private practice in the Rhône-Alpes region, France, between October 2013 and January 2014. GPs' immunisation practices for diphtheria-tetanus-poliomyelitis (DTP), measles-mumps-rubella (MMR), pneumococcal, pertussis, hepatitis B (hepB), human papillomavirus (HPV), seasonal and H1N1 influenza and meningococcal C (menC) vaccines were considered. Divergence was defined by the presence of at least one different immunisation practice between their patients and their children. A total of 693 GPs answered the questionnaire. When considering all investigated vaccines, 45.7 % of divergence was found. Individually, divergence was highest for the newest and more controversial, i.e. HPV (11.8 %), hepB (13.1 %), menC (23.7 %) and pneumococcal (19.8 %) vaccines. Only 73.9 % of GPs declared that they recommended HPV vaccine for their daughters. After multivariate analysis, older age was associated with higher risk of divergence. According to the French 2012 recommendations, GPs were insufficiently immunised, with 88 % for DTP and 72 % for pertussis. GPs declared to recommend vaccination against DTP, pertussis and MMR for their patients and their children in more than 95 % of cases. The declared rates of recommendation were lower than 90 % for other vaccines. These results bring new insight about vaccine hesitancy. GPs have divergent immunisation attitudes toward their relatives and their patients, especially when considering the newest and most controversial vaccines, with HPV vaccine being the main focus of controversies.
authors.affiliation: Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.|GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France.|Centre of Clinical Investigation Vaccinology (CIC) 1408 INSERM, University Hospital of Saint-Etienne, Saint-Etienne, France.
authors.forename: M
authors.initials: M
authors.lastname: Killian
authors.affiliation: GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France.|Centre of Clinical Investigation Vaccinology (CIC) 1408 INSERM, University Hospital of Saint-Etienne, Saint-Etienne, France.
authors.forename: M
authors.initials: M
authors.lastname: Detoc
authors.affiliation: Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.|GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France.|Centre of Clinical Investigation Vaccinology (CIC) 1408 INSERM, University Hospital of Saint-Etienne, Saint-Etienne, France.
authors.forename: P
authors.initials: P
authors.lastname: Berthelot
authors.affiliation: General Practice Department, University of Lyon, Saint-Etienne, France.
authors.forename: R
authors.initials: R
authors.lastname: Charles
authors.affiliation: Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.|GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France.|Centre of Clinical Investigation Vaccinology (CIC) 1408 INSERM, University Hospital of Saint-Etienne, Saint-Etienne, France.
authors.forename: A
authors.initials: A
authors.lastname: Gagneux-Brunon
authors.affiliation: Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.|GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France.|Centre of Clinical Investigation Vaccinology (CIC) 1408 INSERM, University Hospital of Saint-Etienne, Saint-Etienne, France.
authors.forename: F
authors.initials: F
authors.lastname: Lucht
authors.affiliation: University of Lorraine, Paris Descartes University, EA 4360 APEMAC, Nancy, France.|Infectious and Tropical Diseases Department, University Hospital of Nancy, Nancy, France.
authors.forename: C
authors.initials: C
authors.lastname: Pulcini
authors.affiliation: Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France.
authors.forename: S
authors.initials: S
authors.lastname: Barbois
authors.affiliation: Infectious Diseases Department, University Hospital of Saint-Etienne, Saint-Etienne, France. e.botelhonevers@gmail.com.|GIMAP EA 3064 (Groupe Immunité des Muqueuses et Agents Pathogènes), University of Lyon, Saint-Etienne, France. e.botelhonevers@gmail.com.|Centre of Clinical Investigation Vaccinology (CIC) 1408 INSERM, University Hospital of Saint-Etienne, Saint-Etienne, France. e.botelhonevers@gmail.com.
authors.forename: E
authors.initials: E
authors.lastname: Botelho-Nevers
mesh_terms: D000328:Adult; D000367:Age Factors; D000368:Aged; D001291:Attitude of Health Personnel; D005260:Female; D005602:France; D058005:General Practitioners / Q000523:psychology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D010818:Practice Patterns, Physicians'; D011795:Surveys and Questionnaires; D014611:Vaccination / Q000523:psychology*; D014612:Vaccines / Q000008:administration & dosage*
chemical_list: D014612:Vaccines