title: Inclusion of populations at risk of advanced melanoma in an opportunistic targeted screening project involving general practitioners.
abstract: OBJECTIVE
  The study objective was to measure the rates of inclusion of populations at risk of advanced melanoma in a pilot targeted screening project involving general practitioners.
  
  
  METHODS
  This cross-sectional database study compared the inclusion rates of patients who signed inclusion in a targeted screening project with those of patients who did not, during a period in which both groups of patients consulted investigators.
  
  
  METHODS
  Data were extracted from the national healthcare insurance records in western France from 11 April to 30 October 2011.
  
  
  METHODS
  Patients, older than 18, considered for the data extraction had consulted one of the 78 participating GPs during the study period, and were affiliated with the national healthcare insurance.
  
  
  METHODS
  Inclusion in the screening was the main outcome measure. Patients at risk of advanced melanoma were characterized by male gender, age over 50, low income, rural residence, farmer, and presence of chronic disease.
  
  
  RESULTS
  A total of 57,279 patients consulted GPs during the inclusion period and 2711 (4.73%) were included in the targeted screening. Populations at risk of advanced melanoma were less included: men (OR = 0.67; 95%CI [0.61-0.73]; p < 0.001), older than 50 (OR = 0.67; 95%CI [0.60-0.74]; p < 0.001), low income (OR = 0.65; 95%CI [0.55-0.77]; p < 0.001), farmer (OR = 0.23; 95%CI [0.17-0.30]; p < 0.001) and presence of a chronic disease (OR = 0.87; 95%CI [0.77-0.98]; p < 0.028).
  
  
  CONCLUSIONS
  This study demonstrated inequalities in the inclusion of patients in a melanoma screening. Patients at risk of advanced cancer were screened less often. Further studies should focus on GPs ability to identify and screen these patients. KEY POINTS Advanced melanoma is more frequently diagnosed in men, older patients and socioeconomically disadvantaged populations, which leads to survival inequalities. • Despite the involvement of general practitioners, the implementation of targeted melanoma screening did not avoid inclusion inequalities. • Men, older patients, patients suffering from chronic diseases, and low-income patients were less likely to benefit from screening. • The display of a conventional or an alarmist poster in the waiting room did not statistically reduce these inclusion inequalities.
authors.affiliation: a Department of General Practice, Faculty of Medicine , University of Nantes , Nantes , France ;|b French National Institute of Health and Medical Research (INSERM U892)/National Center for Scientific Research (CNRS U6299), Team 2 , Nantes , France ;
authors.forename: Cédric
authors.initials: C
authors.lastname: Rat
authors.affiliation: b French National Institute of Health and Medical Research (INSERM U892)/National Center for Scientific Research (CNRS U6299), Team 2 , Nantes , France ;|c Oncodermatology Department , Nantes University Hospital , Nantes , France ;
authors.forename: Gaelle
authors.initials: G
authors.lastname: Quereux
authors.affiliation: a Department of General Practice, Faculty of Medicine , University of Nantes , Nantes , France ;
authors.forename: Charlotte
authors.initials: C
authors.lastname: Grimault
authors.affiliation: a Department of General Practice, Faculty of Medicine , University of Nantes , Nantes , France ;
authors.forename: Jérémy
authors.initials: J
authors.lastname: Fernandez
authors.affiliation: a Department of General Practice, Faculty of Medicine , University of Nantes , Nantes , France ;
authors.forename: Mickael
authors.initials: M
authors.lastname: Poiraud
authors.affiliation: d Department of Epidemiology and Biostatistics , Nantes University Hospital , Nantes , France ;
authors.forename: Aurélie
authors.initials: A
authors.lastname: Gaultier
authors.affiliation: e Medical Department of the French Health Insurance System , Nantes , France.
authors.forename: Anicet
authors.initials: A
authors.lastname: Chaslerie
authors.affiliation: e Medical Department of the French Health Insurance System , Nantes , France.
authors.forename: Jacques
authors.initials: J
authors.lastname: Pivette
authors.affiliation: b French National Institute of Health and Medical Research (INSERM U892)/National Center for Scientific Research (CNRS U6299), Team 2 , Nantes , France ;|c Oncodermatology Department , Nantes University Hospital , Nantes , France ;
authors.forename: Amir
authors.initials: A
authors.lastname: Khammari
authors.affiliation: b French National Institute of Health and Medical Research (INSERM U892)/National Center for Scientific Research (CNRS U6299), Team 2 , Nantes , France ;|c Oncodermatology Department , Nantes University Hospital , Nantes , France ;
authors.forename: Brigitte
authors.initials: B
authors.lastname: Dreno
authors.affiliation: b French National Institute of Health and Medical Research (INSERM U892)/National Center for Scientific Research (CNRS U6299), Team 2 , Nantes , France ;|d Department of Epidemiology and Biostatistics , Nantes University Hospital , Nantes , France ;
authors.forename: Jean-Michel
authors.initials: JM
authors.lastname: Nguyen
mesh_terms: D000328:Adult; D000368:Aged; D003430:Cross-Sectional Studies; D005260:Female; D005602:France; D058005:General Practitioners / Q000193:education*; D006801:Humans; D007348:Insurance, Health; D008297:Male; D008545:Melanoma / Q000175:diagnosis*; D008875:Middle Aged; D010353:Patient Education as Topic; D057175:Posters as Topic; D012307:Risk Factors; D017678:Sex Distribution; D012878:Skin Neoplasms / Q000175:diagnosis* / Q000473:pathology; D012959:Socioeconomic Factors; D011795:Surveys and Questionnaires; D055815:Young Adult
keywords: Early detection of cancer; France; general practice; melanoma; population characteristics; primary healthcare; screening