title: Polybrominated diphenylethers (PBDEs) and their hydroxylated metabolites (OH-PBDEs) in female serum from Dalian, China.
abstract: Seven polybrominated diphenyl ethers (PBDEs) and eleven hydroxylated PBDEs (OH-PBDEs) were selected to investigate their contamination status in 32 female serum samples from Dalian, China. These studied PBDEs and OH-PBDEs were found in most of the serum samples with the concentrations of ΣPBDEs and ΣOH-PBDEs ranging from 1.07 to 38.7ng/g lipid (median: 5.56ng/g lipid) and from 0.011 to 0.436ng/g lipid (median: 0.069ng/g lipid), respectively. More impressively, BDE-47 and OH-BDE-47 were the predominant congeners in female serum, accounting for 52% of ΣPBDEs and 46% of ΣOH-PBDEs, respectively. Correspondence analysis indicated that significant (p<0.05) positive correlations were observed between BDE-47 and its metabolites such as 6-OH-BDE-47, 3-OH-BDE-47 and 4'-OH-BDE-49. In addition, the positive significant (p<0.05) correlation was shown between ∑PBDEs and lipid contents but between concentrations of ∑PBDEs and ages or BMIs, as well as for ∑OH-PBDEs.
authors.affiliation: Department of breast surgery, The Second Affiliated Hospital of Dalian Medical University, Zhongshan Road 467, Dalian 116023, China.
authors.forename: Yafeng
authors.initials: Y
authors.lastname: Wang
authors.affiliation: Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Environmental Science and Technology, Dalian University of Technology, Linggong Road 2, Dalian 116023, China.
authors.forename: Sisi
authors.initials: S
authors.lastname: Liu
authors.affiliation: Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Environmental Science and Technology, Dalian University of Technology, Linggong Road 2, Dalian 116023, China. Electronic address: hxzhao@dlut.edu.cn.
authors.forename: Hongxia
authors.initials: H
authors.lastname: Zhao
authors.affiliation: Department of breast surgery, The Second Affiliated Hospital of Dalian Medical University, Zhongshan Road 467, Dalian 116023, China.
authors.forename: Guodong
authors.initials: G
authors.lastname: Zhao
authors.affiliation: Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Environmental Science and Technology, Dalian University of Technology, Linggong Road 2, Dalian 116023, China.
authors.forename: Jingwen
authors.initials: J
authors.lastname: Chen
authors.affiliation: 3M Environmental Laboratory, 3M Center, Building 0260-05-N-17, St Paul, MN 55144, USA.
authors.forename: Guangshu
authors.initials: G
authors.lastname: Zhai
authors.affiliation: Department of breast surgery, The Second Affiliated Hospital of Dalian Medical University, Zhongshan Road 467, Dalian 116023, China. Electronic address: z.hddl@hotmail.com.
authors.forename: Haidong
authors.initials: H
authors.lastname: Zhao
mesh_terms: D000328:Adult; D000368:Aged; D002681:China; D004784:Environmental Monitoring; D004785:Environmental Pollutants / Q000097:blood*; D005260:Female; D055768:Halogenated Diphenyl Ethers / Q000097:blood*; D006801:Humans; D006900:Hydroxylation; D008875:Middle Aged
chemical_list: D004785:Environmental Pollutants; D055768:Halogenated Diphenyl Ethers
keywords: Dalian; Female serum; Hydroxylated metabolites (OH-PBDEs); Polybrominated diphenyl ethers (PBDEs)