title: Nanocarriers Usage for Drug Delivery in Cancer Therapy.
abstract: Conventional therapeutic agents have displayed significant shortcomings. For this reason, important achievements have effectively made in biotechnology for delivering the therapeutic agents to the site of action, and diminish side effects. Polymeric carriers, micelles, dendrimers, liposomes, solid lipid carriers, gold carriers, viral carriers, nanotubes and magnetic carriers incorporating cytotoxic therapeutics have developed. To improve biological distribution of therapeutic drugs, some modified carriers have designed in optimal size and modified surface area. Delivery of carriers to target cells could be done by passive and active targeting.
authors.affiliation: Department of Biochemistry, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, IR Iran.
authors.forename: Hadi
authors.initials: H
authors.lastname: Khodabandehloo
authors.affiliation: Institute of Biochemistry and Biophysics, University of Tehran, Tehran, IR Iran.
authors.forename: Hamid
authors.initials: H
authors.lastname: Zahednasab
authors.affiliation: Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.
authors.forename: Asghar
authors.initials: A
authors.lastname: Ashrafi Hafez
keywords: Carrier; Drug Delivery Systems; Nanoparticles; Neoplasms; Therapeutics