title: Acute Intravascular Haemolysis Associated with High Dose Immunoglobulin after Bone Marrow Transplantation for Acute Myelogenous Leukemia.
abstract: A 12-year-old boy developed persistent thrombocytopenia after undergoing bone marrow transplantation for acute myelogenous leukemia. High doses of intravenous immunoglobulins were used to treat overt hemorrhage and a sudden intravascular hemolysis occurred. The serologic findings point to an acute hemolysis secondary to the presence of isohemoagglutinins in the intravenous immunoglobulin preparations.
authors.affiliation: a Department of Paediatric Haematology, University of Milan, San Gerardo Hospital, Monza, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Rovelli
authors.affiliation: a Department of Paediatric Haematology, University of Milan, San Gerardo Hospital, Monza, Italy.
authors.forename: P
authors.initials: P
authors.lastname: D'angelo
authors.affiliation: a Department of Paediatric Haematology, University of Milan, San Gerardo Hospital, Monza, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Balduzzi
authors.affiliation: b Haematology Laboratory, Blood Bank, San Gerardo Hospital, Monza, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Borzini
authors.affiliation: a Department of Paediatric Haematology, University of Milan, San Gerardo Hospital, Monza, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Biondi
authors.affiliation: a Department of Paediatric Haematology, University of Milan, San Gerardo Hospital, Monza, Italy.
authors.forename: C
authors.initials: C
authors.lastname: Uderzo
keywords: High dose immunoglobulin; autoimmune thrombocytopenia; bone marrow transplantation; intravascular haemolysis