title: Towards human-controlled, real-time shape sensing based flexible needle steering for MRI-guided percutaneous therapies.
abstract: BACKGROUND
  Accurate needle placement into soft tissue is essential to percutaneous prostate cancer diagnosis and treatment procedures.
  
  
  METHODS
  This paper discusses the steering of a 20 gauge (G) FBG-integrated needle with three sets of Fiber Bragg Grating (FBG) sensors. A fourth-order polynomial shape reconstruction method is introduced and compared with previous approaches. To control the needle, a bicycle model based navigation method is developed to provide visual guidance lines for clinicians. A real-time model updating method is proposed for needle steering inside inhomogeneous tissue. A series of experiments were performed to evaluate the proposed needle shape reconstruction, visual guidance and real-time model updating methods.
  
  
  RESULTS
  Targeting experiments were performed in soft plastic phantoms and in vitro tissues with insertion depths ranging between 90 and 120 mm. Average targeting errors calculated based upon the acquired camera images were 0.40 ± 0.35 mm in homogeneous plastic phantoms, 0.61 ± 0.45 mm in multilayer plastic phantoms and 0.69 ± 0.25 mm in ex vivo tissue.
  
  
  CONCLUSIONS
  Results endorse the feasibility and accuracy of the needle shape reconstruction and visual guidance methods developed in this work. The approach implemented for the multilayer phantom study could facilitate accurate needle placement efforts in real inhomogeneous tissues. Copyright © 2016 John Wiley & Sons, Ltd.
authors.affiliation: School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, China.|Hackerman 200, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Meng
authors.identifier: http://orcid.org/0000-0003-3648-7917
authors.initials: M
authors.lastname: Li
authors.affiliation: 100 Institute Road, Worcester Polytechnic Institute, Worcester, MA, USA.
authors.forename: Gang
authors.initials: G
authors.lastname: Li
authors.affiliation: Hackerman 200, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Berk
authors.initials: B
authors.lastname: Gonenc
authors.affiliation: School of Mechatronical Engineering, Beijing Institute of Technology, Beijing, China.
authors.forename: Xingguang
authors.initials: X
authors.lastname: Duan
authors.affiliation: Hackerman 200, Johns Hopkins University, Baltimore, MD, USA.
authors.forename: Iulian
authors.initials: I
authors.lastname: Iordachita
mesh_terms: D003199:Computer Systems; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005246:Feedback; D006801:Humans; D061705:Image-Guided Biopsy / Q000295:instrumentation*; D007267:Injections; D053783:Magnetic Resonance Imaging, Interventional / Q000295:instrumentation*; D008328:Man-Machine Systems; D055617:Micro-Electrical-Mechanical Systems / Q000295:instrumentation*; D009339:Needles; D019047:Phantoms, Imaging; D012031:Refractometry / Q000295:instrumentation*; D015203:Reproducibility of Results; D012371:Robotics / Q000295:instrumentation* / Q000379:methods; D012680:Sensitivity and Specificity; D018511:Systems Integration; D014159:Transducers
keywords: FBG sensor; multilayer phantom insertion; needle steering; prostate intervention