title: Insights into Bacteriophage Application in Controlling Vibrio Species.
abstract: Bacterial infections from various organisms including Vibrio sp. pose a serious hazard to humans in many forms from clinical infection to affecting the yield of agriculture and aquaculture via infection of livestock. Vibrio sp. is one of the main foodborne pathogens causing human infection and is also a common cause of losses in the aquaculture industry. Prophylactic and therapeutic usage of antibiotics has become the mainstay of managing this problem, however, this in turn led to the emergence of multidrug resistant strains of bacteria in the environment; which has raised awareness of the critical need for alternative non-antibiotic based methods of preventing and treating bacterial infections. Bacteriophages - viruses that infect and result in the death of bacteria - are currently of great interest as a highly viable alternative to antibiotics. This article provides an insight into bacteriophage application in controlling Vibrio species as well underlining the advantages and drawbacks of phage therapy.
authors.affiliation: Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala LumpurMalaysia; Novel Bacteria and Drug Discovery Research Group, School of Pharmacy, Monash University Malaysia, Selangor Darul EhsanMalaysia.
authors.forename: Vengadesh
authors.initials: V
authors.lastname: Letchumanan
authors.affiliation: Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur Malaysia.
authors.forename: Kok-Gan
authors.initials: KG
authors.lastname: Chan
authors.affiliation: Jeffrey Cheah School of Medicine and Health Sciences, Monash University Malaysia, Selangor Darul Ehsan Malaysia.
authors.forename: Priyia
authors.initials: P
authors.lastname: Pusparajah
authors.affiliation: Novel Bacteria and Drug Discovery Research Group, School of Pharmacy, Monash University Malaysia, Selangor Darul EhsanMalaysia; Center of Health Outcomes Research and Therapeutic Safety, School of Pharmaceutical Sciences, University of Phayao, PhayaoThailand; Pharmaceutical Outcomes Research Center, Faculty of Pharmaceutical Sciences, Naresuan University, PhitsanulokThailand.
authors.forename: Surasak
authors.initials: S
authors.lastname: Saokaew
authors.affiliation: Center of Health Outcomes Research and Therapeutic Safety, School of Pharmaceutical Sciences, University of Phayao, PhayaoThailand; Division of Physiology, School of Medical Sciences, University of Phayao, PhayaoThailand.
authors.forename: Acharaporn
authors.initials: A
authors.lastname: Duangjai
authors.affiliation: Novel Bacteria and Drug Discovery Research Group, School of Pharmacy, Monash University Malaysia, Selangor Darul EhsanMalaysia; Center of Health Outcomes Research and Therapeutic Safety, School of Pharmaceutical Sciences, University of Phayao, PhayaoThailand.
authors.forename: Bey-Hing
authors.initials: BH
authors.lastname: Goh
authors.affiliation: UKM Medical Molecular Biology Institute, UKM Medical Centre, Universiti Kebangsaan Malaysia, Kuala Lumpur Malaysia.
authors.forename: Nurul-Syakima
authors.initials: NS
authors.lastname: Ab Mutalib
authors.affiliation: Novel Bacteria and Drug Discovery Research Group, School of Pharmacy, Monash University Malaysia, Selangor Darul EhsanMalaysia; Center of Health Outcomes Research and Therapeutic Safety, School of Pharmaceutical Sciences, University of Phayao, PhayaoThailand.
authors.forename: Learn-Han
authors.initials: LH
authors.lastname: Lee
keywords: Vibrio sp.; antibiotics; bacterial; bacteriophages; multidrug resistant strains