title: Screening for coeliac disease in adult patients with type 1 diabetes mellitus: myths, facts and controversy.
abstract: This review aims at summarizing the present knowledge on the clinical consequences of concomitant coeliac disease (CD) in adult patients with type 1 diabetes mellitus (T1DM). The cause of the increased prevalence of CD in T1DM patients is a combination of genetic and environmental factors. Current screening guidelines for CD in adult T1DM patients are not uniform. Based on the current evidence of effects of CD on bone mineral density, diabetic complications, quality of life, morbidity and mortality in patients with T1DM, we advise periodic screening for CD in adult T1DM patients to prevent delay in CD diagnosis and subsequent CD and/or T1DM related complications.
authors.affiliation: Department of Gastroenterology and Hepatology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
authors.forename: Sjoerd F
authors.initials: SF
authors.lastname: Bakker
authors.affiliation: Department of Gastroenterology and Hepatology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
authors.forename: Maarten E
authors.initials: ME
authors.lastname: Tushuizen
authors.affiliation: Department of Pathology, Unit Medical Immunology, VU University Medical Centre, Amsterdam, The Netherlands.
authors.forename: Boudewina M E
authors.initials: BM
authors.lastname: von Blomberg
authors.affiliation: Department of Pathology, Unit Medical Immunology, VU University Medical Centre, Amsterdam, The Netherlands.
authors.forename: Hetty J
authors.initials: HJ
authors.lastname: Bontkes
authors.affiliation: Department of Gastroenterology and Hepatology, VU University Medical Centre, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands.
authors.forename: Chris J
authors.initials: CJ
authors.lastname: Mulder
authors.affiliation: Department of Internal Medicine, North West Clinics, Alkmaar, The Netherlands ; Department of Internal Medicine, VU University Medical Centre, Amsterdam, The Netherlands.
authors.forename: Suat
authors.initials: S
authors.lastname: Simsek
keywords: Clinical characteristics; Coeliac disease; Complications and type 1 diabetes mellitus; Gluten free diet; Quality of life; Screening; Tissue-transglutaminase antibodies