title: [Giant Ganglioneuroma of the Spine and Mediastinum].
abstract: The case of a 15-year-old girl with a large ganglioneuroma in the mediastinum and spinal canal is presented. The tumour initially manifested as scoliosis. Its diagnosis was made on the basis of CT scanning and magnetic resonance imaging, and confirmed by thoracoscopic mediastinal biopsy. Radical tumour excision was indicated. The first stage involved removal of the tumour from the spinal canal through a posterior approach, and transpedicular fixation of the spinal column with correction of the curve. At the second-stage procedure, the tumour was removed from the pleural cavity and mediastinum through thoracotomy. At two years after surgery, the spondylodesis was completed with autologous bone grafts that healed within 6 months. At 3-year follow-up the patient was with neither clinical findings, nor subjective complains and imaging methods showed no signs of tumour recurrence.
  
  
  BACKGROUND
  ganglioneuroma, scoliosis, correction, thoracotomy, spinal canal, mediastinum.
authors.affiliation: Klinika spondylochirurgie 1. lékařské fakulty Univerzity Karlovy v Praze a Fakultní nemocnice Motol, Praha.
authors.forename: P
authors.initials: P
authors.lastname: Nesnídal
authors.forename: J
authors.initials: J
authors.lastname: Štulík
authors.forename: R
authors.initials: R
authors.lastname: Lischke
authors.forename: M
authors.initials: M
authors.lastname: Barna
mesh_terms: D000293:Adolescent; D016025:Bone Transplantation / Q000379:methods*; D005260:Female; D005729:Ganglioneuroma / Q000000981:diagnostic imaging* / Q000628:therapy; D006801:Humans; D008279:Magnetic Resonance Imaging / Q000379:methods; D008479:Mediastinal Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D012600:Scoliosis / Q000209:etiology* / Q000628:therapy; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000628:therapy; D013906:Thoracoscopy / Q000379:methods*; D014057:Tomography, X-Ray Computed / Q000379:methods; D016896:Treatment Outcome