title: Intra-Operative Vector Flow Imaging Using Ultrasound of the Ascending Aorta among 40 Patients with Normal, Stenotic and Replaced Aortic Valves.
abstract: Stenosis of the aortic valve gives rise to more complex blood flows with increased velocities. The angle-independent vector flow ultrasound technique transverse oscillation was employed intra-operatively on the ascending aorta of (I) 20 patients with a healthy aortic valve and 20 patients with aortic stenosis before (IIa) and after (IIb) valve replacement. The results indicate that aortic stenosis increased flow complexity (p < 0.0001), induced systolic backflow (p < 0.003) and reduced systolic jet width (p < 0.0001). After valve replacement, the systolic backflow and jet width were normalized (p < 0.52 and p < 0.22), but flow complexity was not (p < 0.0001). Flow complexity (p < 0.0001), systolic jet width (p < 0.0001) and systolic backflow (p < 0.001) were associated with peak systolic velocity. The study found that aortic stenosis changes blood flow in the ascending aorta and valve replacement corrects some of these changes. Transverse oscillation may be useful for assessment of aortic stenosis and optimization of valve surgery.
authors.affiliation: Radiology Department, Rigshospitalet, Copenhagen, Denmark. Electronic address: lindskov@gmail.com.
authors.forename: Kristoffer Lindskov
authors.initials: KL
authors.lastname: Hansen
authors.affiliation: Cardiothoracic Anesthesiology Department, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Hasse
authors.initials: H
authors.lastname: Møller-Sørensen
authors.affiliation: Cardiology Department, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Jesper
authors.initials: J
authors.lastname: Kjaergaard
authors.affiliation: Cardiothoracic Anesthesiology Department, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Maiken Brit
authors.initials: MB
authors.lastname: Jensen
authors.affiliation: Cardiothoracic Surgery Department, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Jens Teglgaard
authors.initials: JT
authors.lastname: Lund
authors.affiliation: Radiology Department, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Mads Møller
authors.initials: MM
authors.lastname: Pedersen
authors.affiliation: Biostatistics Department, University of Copenhagen, Copenhagen, Denmark.
authors.forename: Theis
authors.initials: T
authors.lastname: Lange
authors.affiliation: Center for Fast Ultrasound Imaging, DTU Elektro, Technical University of Denmark, Lyngby, Denmark.
authors.forename: Jørgen Arendt
authors.initials: JA
authors.lastname: Jensen
authors.affiliation: Radiology Department, Rigshospitalet, Copenhagen, Denmark.
authors.forename: Michael Bachmann
authors.initials: MB
authors.lastname: Nielsen
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001011:Aorta / Q000000981:diagnostic imaging / Q000503:physiopathology*; D001021:Aortic Valve / Q000000981:diagnostic imaging / Q000503:physiopathology / Q000601:surgery; D001024:Aortic Valve Stenosis / Q000000981:diagnostic imaging / Q000503:physiopathology* / Q000601:surgery; D001026:Coronary Artery Bypass / Q000379:methods*; D017548:Echocardiography, Transesophageal / Q000379:methods; D005260:Female; D019918:Heart Valve Prosthesis Implantation / Q000379:methods*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016343:Monitoring, Intraoperative / Q000379:methods*; D014463:Ultrasonography / Q000379:methods*
keywords: Aortic valve stenosis; Flow complexity; Intraoperative ultrasound; Secondary flow; Systolic backflow; Transverse oscillation; Vector flow imaging