title: Outcome and complications of combined liver and pancreas resections: a retrospective analysis.
abstract: BACKGROUND
  Combined resections of the liver and pancreas are related to high complication and mortality rates. The present study assessed the outcome of these procedures and identified specific risk factors for morbidity and mortality.
  
  
  METHODS
  Between January 2001 and April 2012, 28 combined liver/pancreas resections were performed at our institution. All patients were retrospectively analysed using a database with regards to baseline characteristics, surgical procedures, complications and survival.
  
  
  RESULTS
  Among the pancreatic resections, there were 12 (42.9%) Kausch-Whipple (KW), 9 (32.1%) pylorus-preserving pancreaticoduodenectomy (PPPD), 6 (21.4%) distal pancreatectomies (DP) and 1 (3.6%) total pancreaticoduodenectomy (TPD). In 12 (48.9%) cases, major complications (grade IIIb-V) were observed. Overall survival was 35 months (SD = 40.5) and the 3-year survival rate was 35.7% (1-year survival rate: 50%).
  
  
  CONCLUSIONS
  Combined resections of the liver and pancreas are associated with high complication rates, especially if major liver resections are performed. Therefore, it is mandatory to do a thorough evaluation of potential patients.
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Christian
authors.initials: C
authors.lastname: Benzing
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Hans-Michael
authors.initials: HM
authors.lastname: Hau
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Georgi
authors.initials: G
authors.lastname: Atanasov
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Johannes
authors.initials: J
authors.lastname: Broschewitz
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Felix
authors.initials: F
authors.lastname: Krenzien
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Michael
authors.initials: M
authors.lastname: Bartels
authors.affiliation: a Department of Visceral, Transplantation, Vascular and Thoracic Surgery , University Hospital of Leipzig , Leipzig , Germany.
authors.forename: Georg
authors.initials: G
authors.lastname: Wiltberger
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D005500:Follow-Up Studies; D005858:Germany / Q000453:epidemiology; D006498:Hepatectomy / Q000379:methods*; D006801:Humans; D008113:Liver Neoplasms / Q000401:mortality / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009017:Morbidity / Q000639:trends; D010180:Pancreatectomy / Q000379:methods*; D010190:Pancreatic Neoplasms / Q000401:mortality / Q000601:surgery*; D011183:Postoperative Complications / Q000453:epidemiology*; D011379:Prognosis; D012189:Retrospective Studies; D012307:Risk Factors; D015996:Survival Rate / Q000639:trends; D055815:Young Adult
keywords: Complications; liver resection; mortality; pancreatic resection