title: Readily Accessible and Predictable Naphthalene-Based Two-Photon Fluorophore with Full Visible-Color Coverage.
abstract: Herein we report 22 acedan-derived, two-photon fluorophores with synthetic feasibility and full coverage of visible wavelength emission. The emission wavelengths were predicted by computational analysis, which enabled us to visualize multicolor images by two-photon excitation with single wavelength, and to design a turn-on, two-photon fluorescence sensor for endogenous H2 O2 in Raw 264.7 macrophage and rat brain hippocampus ex vivo.
authors.affiliation: Department of Chemistry, Seoul National University, Seoul, 08826, Korea.
authors.forename: Ja Young
authors.initials: JY
authors.lastname: Koo
authors.affiliation: Department of Chemistry, Division of Energy System Research, Ajou University, Suwon, 16499, Korea.
authors.forename: Cheol Ho
authors.initials: CH
authors.lastname: Heo
authors.affiliation: Department of Chemistry, Seoul National University, Seoul, 08826, Korea.
authors.forename: Young-Hee
authors.initials: YH
authors.lastname: Shin
authors.affiliation: Department of Chemistry, Seoul National University, Seoul, 08826, Korea.
authors.forename: Dahahm
authors.initials: D
authors.lastname: Kim
authors.affiliation: Department of Chemistry, Division of Energy System Research, Ajou University, Suwon, 16499, Korea.
authors.forename: Chang Su
authors.initials: CS
authors.lastname: Lim
authors.affiliation: Department of Chemistry, Daejin University, Pochun, 11159, Korea.
authors.forename: Bong Rae
authors.initials: BR
authors.lastname: Cho
authors.affiliation: Department of Chemistry, Division of Energy System Research, Ajou University, Suwon, 16499, Korea.
authors.forename: Hwan Myung
authors.initials: HM
authors.lastname: Kim
authors.affiliation: Department of Chemistry, Seoul National University, Seoul, 08826, Korea. sbpark@snu.ac.kr.|Department of Biophysics and Chemical Biology, Seoul National University, Seoul, 08826, Korea. sbpark@snu.ac.kr.
authors.forename: Seung Bum
authors.identifier: http://orcid.org/0000-0003-1753-1433
authors.initials: SB
authors.lastname: Park
keywords: acedan; biosensors; fluorescence; hydrogen peroxide; visible color