title: Herbal Medicines for Asthmatic Inflammation: From Basic Researches to Clinical Applications.
abstract: Asthma is one of the most common chronic inflammatory disorders, associated with reversible airflow obstruction, airway hyperresponsiveness, and airway remodeling. This disease has a significant impact on individuals, their families, and society. Standardized therapeutics such as inhaled corticosteroid in combination with long acting β2 agonist have been applied for asthma control; however, complementary and alternative medicines, especially herbal medicines, are still widely used all over the world. A growing body of literature suggests that various herbals or related products might be effective in inhibiting asthmatic inflammation. In this review, we summarize recent advances about the mechanistic studies of herbal medicines on allergic airway inflammation in animal models and their potential application into clinic for asthma control.
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
authors.forename: Fang
authors.identifier: 0000-0001-6392-8605
authors.initials: F
authors.lastname: Liu
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
authors.forename: Nan-Xia
authors.initials: NX
authors.lastname: Xuan
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
authors.forename: Song-Min
authors.initials: SM
authors.lastname: Ying
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
authors.forename: Wen
authors.initials: W
authors.lastname: Li
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China.
authors.forename: Zhi-Hua
authors.identifier: 0000-0002-4390-7636
authors.initials: ZH
authors.lastname: Chen
authors.affiliation: Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China; State Key Laboratory of Respiratory Diseases, Guangzhou 510120, China.
authors.forename: Hua-Hao
authors.identifier: 0000-0002-0350-5480
authors.initials: HH
authors.lastname: Shen
mesh_terms: D000818:Animals; D001249:Asthma / Q000188:drug therapy*; D029001:Herbal Medicine / Q000379:methods*; D006801:Humans; D007249:Inflammation / Q000188:drug therapy*