title: [THE ROLE OF OSTEOCALCIN IN COURSE OF OSTEOARTHRITIS AND TYPE 2 DIABETES MELLITUS].
abstract: We studied the level of osteocalcin and its relationships with carbohydrate metabolism and clinical and radiographic changes in patients with osteoarthritis (OA) and type 2 diabetes mellitus (DM 2) and their combination. Significant negative correlation between the level of osteocalcin and carbohydrate metabolism, and clinical and radiographic changes in patients with OA and DM 2 was found. We determined, that negative correlation of osteocalcin with carbohydrate metabolism and radiographic changes, and more pronounced pain in OA maybe an indication that the lack of production of osteocalcin leads to more severe changes during the OA on the background of DM 2 diabetes mellitus.
authors.forename: L V
authors.initials: LV
authors.lastname: Zhuravlyova
authors.forename: M O
authors.initials: MO
authors.lastname: Oliinyk
mesh_terms: D001786:Blood Glucose / Q000378:metabolism; D001835:Body Weight; D050260:Carbohydrate Metabolism; D016022:Case-Control Studies; D059350:Chronic Pain / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D003924:Diabetes Mellitus, Type 2 / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D005260:Female; D006442:Glycated Hemoglobin / Q000378:metabolism; D006801:Humans; D007328:Insulin / Q000097:blood; D007333:Insulin Resistance; D008297:Male; D008875:Middle Aged; D010003:Osteoarthritis / Q000097:blood* / Q000150:complications / Q000000981:diagnostic imaging / Q000473:pathology; D015675:Osteocalcin / Q000097:blood*; D011859:Radiography
chemical_list: D001786:Blood Glucose; D006442:Glycated Hemoglobin; D007328:Insulin; D015675:Osteocalcin; C517652:hemoglobin A1c protein, human