title: Suppressive Effects of Tea Catechins on Breast Cancer.
abstract: Tea leaf (Camellia sinensis) is rich in catechins, which endow tea with various health benefits. There are more than ten catechin compounds in tea, among which epigallocatechingallate (EGCG) is the most abundant. Epidemiological studies on the association between tea consumption and the risk of breast cancer were summarized, and the inhibitory effects of tea catechins on breast cancer, with EGCG as a representative compound, were reviewed in the present paper. The controversial results regarding the role of tea in breast cancer and areas for further study were discussed.
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. gzzyzj_2009@vip.sina.com.|National Tea and Tea product Quality Supervision and Inspection Center (Guizhou), Zunyi 563100, China. gzzyzj_2009@vip.sina.com.
authors.forename: Li-Ping
authors.initials: LP
authors.lastname: Xiang
authors.affiliation: National Tea and Tea product Quality Supervision and Inspection Center (Guizhou), Zunyi 563100, China. wangaocn@gmail.com.
authors.forename: Ao
authors.initials: A
authors.lastname: Wang
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. jianhuiye@zju.edu.cn.
authors.forename: Jian-Hui
authors.initials: JH
authors.lastname: Ye
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. xqzheng@zju.edu.cn.
authors.forename: Xin-Qiang
authors.initials: XQ
authors.lastname: Zheng
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. curtpolito@outlook.com.
authors.forename: Curt Anthony
authors.initials: CA
authors.lastname: Polito
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. jllu@zju.edu.cn.
authors.forename: Jian-Liang
authors.initials: JL
authors.lastname: Lu
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. qsli@zju.edu.cn.
authors.forename: Qing-Sheng
authors.initials: QS
authors.lastname: Li
authors.affiliation: Tea Research Institute, Zhejiang University, # 866 Yuhangtang Road, Hangzhou 310058, China. yrliang@zju.edu.cn.|National Tea and Tea product Quality Supervision and Inspection Center (Guizhou), Zunyi 563100, China. yrliang@zju.edu.cn.
authors.forename: Yue-Rong
authors.initials: YR
authors.lastname: Liang
mesh_terms: D020533:Angiogenesis Inhibitors / Q000378:metabolism / Q000627:therapeutic use; D000818:Animals; D016588:Anticarcinogenic Agents / Q000378:metabolism / Q000627:therapeutic use*; D000975:Antioxidants / Q000627:therapeutic use; D001943:Breast Neoplasms / Q000453:epidemiology / Q000517:prevention & control*; D028241:Camellia sinensis / Q000737:chemistry*; D002392:Catechin / Q000378:metabolism / Q000627:therapeutic use*; D019587:Dietary Supplements; D019317:Evidence-Based Medicine; D005260:Female; D005511:Food Handling; D055951:Functional Food; D005707:Gallic Acid / Q000031:analogs & derivatives / Q000627:therapeutic use; D006801:Humans; D007408:Intestinal Absorption; D009389:Neovascularization, Pathologic / Q000453:epidemiology / Q000517:prevention & control; D010084:Oxidation-Reduction; D010936:Plant Extracts / Q000627:therapeutic use; D018515:Plant Leaves / Q000737:chemistry*; D015203:Reproducibility of Results; D012306:Risk; D013662:Tea
chemical_list: D020533:Angiogenesis Inhibitors; D016588:Anticarcinogenic Agents; D000975:Antioxidants; D010936:Plant Extracts; D013662:Tea; C491764:epigallocatecol gallate; D005707:Gallic Acid; D002392:Catechin
keywords: Camellia sinensis; DNA methylation; anti-proliferation; anticancer; antioxidant; metastasis; signaling pathway