title: [COPD and bone].
abstract: Chronic obstructive pulmonary disease(COPD)is a chronic inflammatory airway disease associated with various systemic comorbidities including osteoporosis. Osteoporosis is extremely common in COPD patients;up to 80%prevalence of vertebral fracture has been reported. However, its low awareness has left many patients untreated. Although pathophysiology of COPD-associated osteoporosis is largely unknown, multiple risk factors for osteoporosis are present, such as smoking, low body weight, systemic inflammation, vitamin D insufficiency, hypoxia. Further research to elucidate its pathophysiology is needed. But, more importantly, increased awareness of its significance is urgently called upon.
authors.affiliation: Third Department of Medicine, Teikyo University Chiba Medical Center, Japan.
authors.forename: Ryo
authors.initials: R
authors.lastname: Okazaki
mesh_terms: D015519:Bone Density; D001842:Bone and Bones / Q000503:physiopathology*; D050723:Fractures, Bone / Q000209:etiology; D006801:Humans; D010024:Osteoporosis / Q000209:etiology* / Q000503:physiopathology; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D012307:Risk Factors