title: Chemical Amination via Cycloaddition of Graphene for Use in a Glucose Sensor.
abstract: Graphene was chemically aminated via cycloaddition. Aziridine-ring linkages were formed by covalently modifying the C-C double bonds in graphene. The aminated graphene presents an enhanced hydrophilicity, the contact angle with water decreases from 80.5 degrees to 58.5 degrees. And the conductivity of aminated graphene exhibits exponential decay as the reaction time increase. If the reaction time is 90 min, the resistance of aminated graphene was increased from -32 Ω to -2744 Ω. Because the amino group has good biocompatibility, the aminated graphene is designed for use as an enzyme sensor platform, such as glucose sensor based on glucose oxidase. The aminated graphene exhibited a good detection response for glucose. The increase in device current is about 12% in 1.2 mg/mL glucose solution.
authors.forename: Hongyi
authors.initials: H
authors.lastname: Qin
authors.forename: Taehyun
authors.initials: T
authors.lastname: Hwang
authors.forename: Chisung
authors.initials: C
authors.lastname: Ahn
authors.forename: Jang Ah
authors.initials: JA
authors.lastname: Kim
authors.forename: Yinhua
authors.initials: Y
authors.lastname: Jin
authors.forename: Yujin
authors.initials: Y
authors.lastname: Cho
authors.forename: Cheolmin
authors.initials: C
authors.lastname: Shin
authors.forename: Taesung
authors.initials: T
authors.lastname: Kim
mesh_terms: D000588:Amines / Q000737:chemistry*; D015374:Biosensing Techniques / Q000295:instrumentation*; D003217:Conductometry / Q000295:instrumentation*; D003432:Cross-Linking Reagents / Q000737:chemistry; D004553:Electric Conductivity; D004566:Electrodes; D004867:Equipment Design; D019544:Equipment Failure Analysis; D005947:Glucose / Q000032:analysis* / Q000737:chemistry; D006108:Graphite / Q000737:chemistry*; D053758:Nanoparticles / Q000737:chemistry* / Q000648:ultrastructure; D015203:Reproducibility of Results; D012680:Sensitivity and Specificity
chemical_list: D000588:Amines; D003432:Cross-Linking Reagents; D006108:Graphite; D005947:Glucose