title: Astigmatism corrected common path probe for optical coherence tomography.
abstract: Optical coherence tomography (OCT) catheters for intraluminal imaging are subject to various artifacts due to reference-sample arm dispersion imbalances and sample arm beam astigmatism. The goal of this work was to develop a probe that minimizes such artifacts.
  
  
  
  Our probe was fabricated using a single mode fiber at the tip of which a glass spacer and graded index objective lens were spliced to achieve the desired focal distance. The signal was reflected using a curved reflector to correct for astigmatism caused by the thin, protective, transparent sheath that surrounds the optics. The probe design was optimized using Zemax, a commercially available optical design software. Common path interferometric operation was achieved using Fresnel reflection from the tip of the focusing graded index objective lens. The performance of the probe was tested using a custom designed spectrometer-based OCT system.
  
  
  
  The probe achieved an axial resolution of 15.6 μm in air, a lateral resolution 33 μm, and a sensitivity of 103 dB. A scattering tissue phantom was imaged to test the performance of the probe for astigmatism correction. Images of the phantom confirmed that this common-path, astigmatism-corrected OCT imaging probe had minimal artifacts in the axial, and lateral dimensions.
  
  
  
  In this work, we developed an astigmatism-corrected, common path probe that minimizes artifacts associated with standard OCT probes. This design may be useful for OCT applications that require high axial and lateral resolutions. Lasers Surg. Med. 49:312-318, 2017. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Wellman Center for Photomedicine, Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, Massachusetts.|Harvard Medical School, 25 Shattuck St, Boston, 02115, Massachusetts.
authors.forename: Kanwarpal
authors.initials: K
authors.lastname: Singh
authors.affiliation: Wellman Center for Photomedicine, Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, Massachusetts.|Healthcare Optics Research Laboratory, Canon USA., Inc., 210 Broadway, 3rd Floor, Cambridge, 02139, Massachusetts.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yamada
authors.affiliation: Wellman Center for Photomedicine, Massachusetts General Hospital, 55 Fruit Street, Boston, 02114, Massachusetts.|Harvard Medical School, 25 Shattuck St, Boston, 02115, Massachusetts.
authors.forename: Guillermo
authors.initials: G
authors.lastname: Tearney
mesh_terms: D001251:Astigmatism / Q000000981:diagnostic imaging* / Q000601:surgery; D004867:Equipment Design; D004869:Equipment Safety; D005336:Fiber Optic Technology / Q000379:methods*; D006801:Humans; D008866:Microsurgery / Q000379:methods; D019047:Phantoms, Imaging; D041623:Tomography, Optical Coherence / Q000295:instrumentation*
keywords: aberration compensation; imaging systems