title: Psoriatic arthritis: lessons from imaging studies and implications for therapy.
abstract: Modern imaging may aid in the diagnosis, prognosis and monitoring of therapeutic response in psoriatic arthritis (PsA). Detection of osteitis and technical advances like whole body magnetic resonance imaging (MRI) exemplify the value of this technology. Areas covered: Ultrasound (US) provides a clinic-based tool for evaluating both joint pathologies and extra-articular structures (especially enthesitis) including skin and nail disease. Recent studies have demonstrated subclinical disease in psoriasis without arthritis, as well as in PsA, with implications for diagnosis and treatment classification. Modern imaging can also facilitate decisions on tapering of expensive biologics, though real-world clinical studies are still lacking. Expert commentary: The increase in novel PsA therapies should increase the utilization of modern imaging, providing both increased validation of imaging biomarkers as well as responsive outcome measures.
authors.affiliation: a Clinical Immunology & Rheumatology , Christian Medical College , Vellore , India.
authors.forename: Ashish J
authors.initials: AJ
authors.lastname: Mathew
authors.affiliation: b Leeds Institute of Rheumatic and Musculoskeletal Medicine , University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds , UK.
authors.forename: Laura C
authors.initials: LC
authors.lastname: Coates
authors.affiliation: a Clinical Immunology & Rheumatology , Christian Medical College , Vellore , India.
authors.forename: Debashish
authors.initials: D
authors.lastname: Danda
authors.affiliation: b Leeds Institute of Rheumatic and Musculoskeletal Medicine , University of Leeds & NIHR Leeds Musculoskeletal Biomedical Research Unit, Leeds , UK.
authors.forename: Philip G
authors.initials: PG
authors.lastname: Conaghan
mesh_terms: D000818:Animals; D015535:Arthritis, Psoriatic / Q000000981:diagnostic imaging* / Q000628:therapy; D001688:Biological Products / Q000627:therapeutic use; D006801:Humans; D008279:Magnetic Resonance Imaging; D010000:Osteitis / Q000000981:diagnostic imaging* / Q000628:therapy; D011379:Prognosis; D014463:Ultrasonography
chemical_list: D001688:Biological Products
keywords: MRI; Psoriasis; psoriatic arthritis; ultrasound