title: Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity.
abstract: The aim of this work was to study the butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1. Results showed that Clostridium sp. S1 produced butyric acid by simultaneously utilizing glucose and mannose in softwood hydrolysate and, more remarkably, it consumed acetic acid in hydrolysate. Clostridium sp. S1 utilized each of glucose, mannose, and xylose as well as mixed sugars simultaneously with partially repressed xylose utilization. When softwood (Japanese larch) hydrolysate containing glucose and mannose as the main sugars was used, Clostridium sp. S1 produced 21.17g/L butyric acid with the yield of 0.47g/g sugar and the selectivity of 1 (g butyric acid/g total acids) owing to the consumption of acetic acid in hydrolysate. The results demonstrate potential of Clostridium sp. S1 to produce butyric acid selectively and effectively from hydrolysate not only by utilizing mixed sugars simultaneously but also by converting acetic acid to butyric acid.
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea; Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea.
authors.forename: Minsun
authors.initials: M
authors.lastname: Kim
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea; Clean Energy and Chemical Engineering, Korea University of Science and Technology, Daejeon, Republic of Korea.
authors.forename: Ki-Yeon
authors.initials: KY
authors.lastname: Kim
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
authors.forename: Kyung Min
authors.initials: KM
authors.lastname: Lee
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea.
authors.forename: Sung Hun
authors.initials: SH
authors.lastname: Youn
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea; Clean Energy and Chemical Engineering, Korea University of Science and Technology, Daejeon, Republic of Korea.
authors.forename: Sun-Mi
authors.initials: SM
authors.lastname: Lee
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea; Clean Energy and Chemical Engineering, Korea University of Science and Technology, Daejeon, Republic of Korea.
authors.forename: Han Min
authors.initials: HM
authors.lastname: Woo
authors.affiliation: Department of Chemical and Biological Engineering, Korea University, Seoul, Republic of Korea.
authors.forename: Min-Kyu
authors.initials: MK
authors.lastname: Oh
authors.affiliation: Clean Energy Research Center, Korea Institute of Science and Technology (KIST), Seoul, Republic of Korea; Clean Energy and Chemical Engineering, Korea University of Science and Technology, Daejeon, Republic of Korea. Electronic address: yum@kist.re.kr.
authors.forename: Youngsoon
authors.initials: Y
authors.lastname: Um
mesh_terms: D019342:Acetic Acid / Q000378:metabolism; D020148:Butyric Acid / Q000138:chemical synthesis*; D003013:Clostridium / Q000378:metabolism*; D005285:Fermentation / Q000502:physiology; D005947:Glucose / Q000378:metabolism; D008358:Mannose / Q000378:metabolism; D014934:Wood / Q000737:chemistry* / Q000382:microbiology*; D014994:Xylose / Q000378:metabolism
chemical_list: D020148:Butyric Acid; D014994:Xylose; D005947:Glucose; D008358:Mannose; D019342:Acetic Acid
keywords: Acetic acid; Butyric acid fermentation; Clostridium sp. S1; Softwood hydrolysate