title: Venlafaxine augmentation with agomelatine in a patient with obsessive-compulsive disorder and suicidal behaviors.
abstract: Obsessive-compulsive disorder is a chronic and disabling condition that often proves to be treatment resistant. Of the patients suffering from obsessive-compulsive disorder, 10%-27% may attempt suicide at least once in their life. We report the case of a patient who presented severe obsessive-compulsive disorder symptoms and attempted suicide ingesting 25 tablets of fluoxetine (20 mg). The patient was treated with venlafaxine and agomelatine and showed improvement of obsessive symptoms and suicidal ideation. Future studies are needed to investigate this treatment regime in large cohorts of obsessive-compulsive disorder patients with suicidal ideation.
authors.affiliation: Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
authors.forename: Maria S
authors.initials: MS
authors.lastname: Signorelli
authors.affiliation: Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy; Department of Interprofessional Health Sciences and Health Administration, Seton Hall University, South Orange, NJ, USA.
authors.forename: Carmen
authors.initials: C
authors.lastname: Concerto
authors.affiliation: Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
authors.forename: Eliana
authors.initials: E
authors.lastname: Battaglia
authors.affiliation: Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
authors.forename: Maria C
authors.initials: MC
authors.lastname: Costanzo
authors.affiliation: Department of Interprofessional Health Sciences and Health Administration, Seton Hall University, South Orange, NJ, USA.
authors.forename: Fortunato
authors.initials: F
authors.lastname: Battaglia
authors.affiliation: Psychiatry Unit, Department of Clinical and Experimental Medicine, University of Catania, Catania, Italy.
authors.forename: Eugenio
authors.initials: E
authors.lastname: Aguglia
keywords: Agomelatine; obsessive-compulsive disorder; suicidal ideation; treatment