title: Association between theta power in 6-month old infants at rest and maternal PTSD severity: A pilot study.
abstract: Compared to infants born to mothers without PTSD, infants born to mothers with active PTSD develop poorer behavioral reactivity and emotional regulation. However, the association between perinatal maternal PTSD and infant neural activation remains largely unknown. This pilot study (N=14) examined the association between perinatal PTSD severity and infant frontal neural activity, as measured by MEG theta power during rest. Results indicated that resting left anterior temporal/frontal theta power was correlated with perinatal PTSD severity (p=0.004). These findings suggest delayed cortical maturation in infants whose mothers had higher perinatal PTSD severity and generate questions regarding perinatal PTSD severity and infant neurophysiological consequences.
authors.affiliation: Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Boulevard, SE, MSC11-6280, Albuquerque, NM 87106, USA. Electronic address: psanjuan@unm.edu.
authors.forename: Pilar M
authors.initials: PM
authors.lastname: Sanjuan
authors.affiliation: Center on Alcoholism, Substance Abuse, and Addictions, University of New Mexico, 2650 Yale Boulevard, SE, MSC11-6280, Albuquerque, NM 87106, USA. Electronic address: cporemba@unm.edu.
authors.forename: Carly
authors.initials: C
authors.lastname: Poremba
authors.affiliation: The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, 1101 Yale Blvd, NE, Albuquerque, NM 87106, USA. Electronic address: lflynn@mrn.org.
authors.forename: Lucinda R
authors.initials: LR
authors.lastname: Flynn
authors.affiliation: Department of Pediatrics, University of Mississippi Medical Center, 2500 N. State St., Jackson, MS 39216, USA. Electronic address: rsavich@umc.edu.
authors.forename: Renate
authors.initials: R
authors.lastname: Savich
authors.affiliation: Department of Pediatrics, University of Mississippi Medical Center, 2500 N. State St., Jackson, MS 39216, USA. Electronic address: rannett@umc.edu.
authors.forename: Robert D
authors.initials: RD
authors.lastname: Annett
authors.affiliation: The Mind Research Network, Lovelace Biomedical and Environmental Research Institute, 1101 Yale Blvd, NE, Albuquerque, NM 87106, USA. Electronic address: jstephen@mrn.org.
authors.forename: Julia
authors.initials: J
authors.lastname: Stephen
mesh_terms: D002540:Cerebral Cortex / Q000502:physiology*; D016241:Child of Impaired Parents; D005260:Female; D005865:Gestational Age; D006801:Humans; D007223:Infant; D007234:Infant, Premature; D015225:Magnetoencephalography; D009035:Mothers / Q000523:psychology*; D009483:Neuropsychological Tests; D010865:Pilot Projects; D012720:Severity of Illness Index; D013313:Stress Disorders, Post-Traumatic / Q000523:psychology*; D013826:Theta Rhythm
keywords: Infant; Left anterior temporal; Magnetoencephalography; Perinatal; Posttraumatic stress disorder; Theta power