title: PURLs: More isn't better with acute low back pain treatment.
abstract: Adding cyclobenzaprine or oxycodone/acetaminophen to naproxen for the treatment of acute low back pain does nothing more than increase adverse effects.
authors.affiliation: Department of Family and Community Medicine, University of Missouri-Columbia, MO, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Frazer
authors.affiliation: Department of Family and Community Medicine, University of Missouri-Columbia, MO, USA.
authors.forename: James J
authors.initials: JJ
authors.lastname: Stevermer
mesh_terms: D000082:Acetaminophen / Q000627:therapeutic use*; D000639:Amitriptyline / Q000031:analogs & derivatives* / Q000627:therapeutic use; D004338:Drug Combinations; D005260:Female; D006801:Humans; D017116:Low Back Pain / Q000188:drug therapy*; D008297:Male; D009125:Muscle Relaxants, Central / Q000627:therapeutic use*; D009288:Naproxen / Q000627:therapeutic use*; D010098:Oxycodone / Q000627:therapeutic use*; D010147:Pain Measurement; D016032:Randomized Controlled Trials as Topic; D016896:Treatment Outcome
chemical_list: D004338:Drug Combinations; D009125:Muscle Relaxants, Central; C514822:oxycodone-acetaminophen; D000639:Amitriptyline; D000082:Acetaminophen; D009288:Naproxen; C004704:cyclobenzaprine; D010098:Oxycodone