title: Effect of Fluoride Varnish on Enamel Remineralization in Anterior Teeth with Molar Incisor Hypomineralization.
abstract: OBJECTIVE
  The objective of this study was to investigate the effect of fluoride varnish on remineralization of anterior teeth affected by Molar-Incisor Hypomineralization (MIH) by means of Quantitative Light-Induced Fluorescence- QLF.
  
  
  METHODS
  Fifty-one healthy 9 - 12- year-old children were selected according to different clinically diagnosed levels of MIH, proposed by the European Academy of Pediatric Dentistry (2003) (considering the most severe lesion per patient, n= 51 lesions), and randomly divided into two groups: (1) four applications of 5% NaF varnish, with one-week interval, and (2) usual home care- control. At each visit, the mean change in fluorescence and area of lesion were measured by QLF. The data were analyzed by repeated measures ANOVA and Tukey's test.
  
  
  RESULTS
  All patients showed enamel alterations in first permanent molars and incisors, frequently with two molars affected by MIH (41.1%). There was no statically significant difference in the mean of fluorescence and area of lesion between groups over the studied time.
  
  
  CONCLUSIONS
  We observed no favorable effect on the remineralization of MIH lesions in anterior teeth after four applications of fluoride varnish.
authors.forename: Manuel
authors.initials: M
authors.lastname: Restrepo
authors.forename: Fabiano
authors.initials: F
authors.lastname: Jeremias
authors.forename: Lourdes
authors.initials: L
authors.lastname: Santos-Pinto
authors.forename: Rita Cl
authors.initials: RC
authors.lastname: Cordeiro
authors.forename: Angela Cc
authors.initials: AC
authors.lastname: Zuanon
mesh_terms: D002327:Cariostatic Agents / Q000627:therapeutic use*; D002648:Child; D003743:Dental Enamel / Q000187:drug effects*; D003744:Dental Enamel Hypoplasia / Q000188:drug therapy*; D005260:Female; D005453:Fluorescence; D005460:Fluorides, Topical / Q000627:therapeutic use*; D005500:Follow-Up Studies; D006801:Humans; D007180:Incisor / Q000187:drug effects; D054020:Lasers, Gas; D008297:Male; D012969:Sodium Fluoride / Q000627:therapeutic use; D014089:Tooth Remineralization / Q000379:methods*; D014100:Toothpastes / Q000627:therapeutic use; D016896:Treatment Outcome
chemical_list: D002327:Cariostatic Agents; D005460:Fluorides, Topical; D014100:Toothpastes; D012969:Sodium Fluoride
keywords: Fluorescence; Fluoride; Molar Incisor Hypomineralization; Tooth remineralization