title: Aneurysmal subarachnoid hemorrhage and severe, catheter-induced vasospasm associated with excessive consumption of a caffeinated energy drink.
abstract: Excessive consumption of over-the-counter stimulants is associated with coronary vasospasm, thrombotic complications, and sudden cardiac death. Their effects on cerebrovascular physiology are not yet described in the neurointerventional literature. Patients are increasingly exposed to high levels of these vasoactive substances in the form of caffeinated energy drinks and specialty coffees. We report a case of aneurysmal subarachnoid hemorrhage (SAH) and severe, catheter-induced vasospasm during attempted endovascular repair of a ruptured anterior communicating artery (AComA) aneurysm in the setting of excessive energy drink consumption. We review the literature and alert clinicians to this potentially serious complication.
authors.affiliation: Departments of Neurosurgery and of Radiology & Biomedical Imaging, Section of Neurovascular Surgery, Yale University School of Medicine/Yale-New Haven Hospital, USA.
authors.forename: Ryan A
authors.initials: RA
authors.lastname: Grant
authors.affiliation: Departments of Neurosurgery and of Radiology & Biomedical Imaging, Section of Neurovascular Surgery, Yale University School of Medicine/Yale-New Haven Hospital, USA.
authors.forename: Branden J
authors.initials: BJ
authors.lastname: Cord
authors.affiliation: Yale University School of Medicine, USA.
authors.forename: Lovemore
authors.initials: L
authors.lastname: Kuzomunhu
authors.affiliation: Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine/Yale-New Haven Hospital, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Sheth
authors.affiliation: Division of Neurocritical Care and Emergency Neurology, Department of Neurology, Yale University School of Medicine/Yale-New Haven Hospital, USA.
authors.forename: Emily
authors.initials: E
authors.lastname: Gilmore
authors.affiliation: Departments of Neurosurgery and of Radiology & Biomedical Imaging, Section of Neurovascular Surgery, Yale University School of Medicine/Yale-New Haven Hospital, USA charles.matouk@yale.edu.
authors.forename: Charles C
authors.initials: CC
authors.lastname: Matouk
mesh_terms: D000328:Adult; D020771:Anterior Cerebral Artery / Q000000981:diagnostic imaging; D002110:Caffeine / Q000009:adverse effects*; D057785:Catheters; D000697:Central Nervous System Stimulants / Q000009:adverse effects*; D002533:Cerebral Angiography; D057510:Endovascular Procedures; D061215:Energy Drinks / Q000009:adverse effects*; D005260:Female; D006801:Humans; D011183:Postoperative Complications / Q000000981:diagnostic imaging*; D013345:Subarachnoid Hemorrhage / Q000139:chemically induced* / Q000000981:diagnostic imaging / Q000601:surgery; D016896:Treatment Outcome; D020301:Vasospasm, Intracranial / Q000000981:diagnostic imaging / Q000209:etiology*
chemical_list: D000697:Central Nervous System Stimulants; D002110:Caffeine
keywords: Caffeine; catheter-induced vasospasm; energy drink; subarachnoid hemorrhage; thrombosis