title: Magnetic porous carbon derived from a metal-organic framework as a magnetic solid-phase extraction adsorbent for the extraction of sex hormones from water and human urine.
abstract: An iron-embedded porous carbon material (MIL-53-C) was fabricated by the direct carbonization of MIL-53. The MIL-53-C possesses a high surface area and good magnetic behavior. The structure, morphology, magnetic property, and porosity of the MIL-53-C were studied by scanning electron microscopy, transmission electron microscopy, vibrating sample magnetometry, and N2 adsorption. With the use of MIL-53-C as the magnetic solid-phase extraction adsorbent, a simple and efficient method was developed for the magnetic solid-phase extraction of three hormones from water and human urine samples before high-performance liquid chromatography with UV detection. The developed method exhibits a good linear response in the range of 0.02-100 ng/mL for water and 0.5-100 ng/mL for human urine samples, respectively. The limit of detection (S/N = 3) for the analytes was 0.005-0.01 ng/mL for water sample and 0.1-0.3 ng/mL for human urine sample. The limit of quantification (S/N = 10) of the analytes were in the range of 0.015-0.030 and 0.3-0.9 ng/mL, respectively.
authors.affiliation: College of Landscape and Travel, Agricultural University of Hebei, Baoding, China.
authors.forename: Ruiyang
authors.initials: R
authors.lastname: Ma
authors.affiliation: Department of Chemistry, College of Science, Agricultural University of Hebei, Baoding, China.
authors.forename: Lin
authors.initials: L
authors.lastname: Hao
authors.affiliation: Department of Chemistry, College of Science, Agricultural University of Hebei, Baoding, China.
authors.forename: Junmin
authors.initials: J
authors.lastname: Wang
authors.affiliation: Department of Chemistry, College of Science, Agricultural University of Hebei, Baoding, China.
authors.forename: Chun
authors.initials: C
authors.lastname: Wang
authors.affiliation: Department of Chemistry, College of Science, Agricultural University of Hebei, Baoding, China.
authors.forename: Qiuhua
authors.initials: Q
authors.lastname: Wu
authors.affiliation: College of Landscape and Travel, Agricultural University of Hebei, Baoding, China. zhiwang2000@hotmail.com, zhiwang2013@aliyun.com.|Department of Chemistry, College of Science, Agricultural University of Hebei, Baoding, China. zhiwang2000@hotmail.com, zhiwang2013@aliyun.com.
authors.forename: Zhi
authors.initials: Z
authors.lastname: Wang
mesh_terms: D000327:Adsorption; D002244:Carbon / Q000737:chemistry; D002851:Chromatography, High Pressure Liquid; D012739:Gonadal Steroid Hormones / Q000737:chemistry / Q000302:isolation & purification* / Q000652:urine; D006801:Humans; D057230:Limit of Detection; D008280:Magnetics / Q000295:instrumentation / Q000379:methods*; D000073396:Metal-Organic Frameworks / Q000737:chemistry*; D016062:Porosity; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D012739:Gonadal Steroid Hormones; D000073396:Metal-Organic Frameworks; D014874:Water Pollutants, Chemical; D002244:Carbon
keywords: High-performance liquid chromatography; Magnetic solid-phase extraction; Porous carbon; Sex hormones