title: ACUTE PHASE PROTEINS AS A MARKER OF RESPIRATORY INFLAMMATION IN PRZEWALSKI'S HORSE (EQUUS FERUS PRZEWALSKII).
abstract: Acute phase proteins are sensitive markers of inflammation, which are highly conserved across taxa. Although the utility of these proteins are becoming well defined in human and domestic animal medical fields, their role in nondomestic species remains unclear. In this communication, a 20-yr-old Przewalski's horse was presented for unresolving aspiration pneumonia, which cultured a unique Actinomyces-like bacteria. Despite waxing and waning clinical signs and minimal changes on baseline hematologic analysis, protein electrophoresis, serum amyloid A, and surfactant protein D serum concentrations showed changes that more accurately reflected the clinical severity of this case.
authors.forename: Samantha J
authors.initials: SJ
authors.lastname: Sander
authors.forename: Priscilla H
authors.initials: PH
authors.lastname: Joyner
authors.forename: Carolyn
authors.initials: C
authors.lastname: Cray
authors.forename: David S
authors.initials: DS
authors.lastname: Rotstein
authors.forename: Copper
authors.initials: C
authors.lastname: Aitken-Palmer
mesh_terms: D000209:Acute-Phase Proteins / Q000235:genetics / Q000378:metabolism*; D000818:Animals; D015415:Biomarkers; D006734:Horse Diseases / Q000097:blood* / Q000378:metabolism; D006736:Horses; D007249:Inflammation / Q000097:blood / Q000378:metabolism / Q000662:veterinary*; D012140:Respiratory Tract Diseases / Q000097:blood / Q000378:metabolism / Q000662:veterinary*
chemical_list: D000209:Acute-Phase Proteins; D015415:Biomarkers
keywords: Acute phase protein; Equus ferus przewalskii; Przewalski's horse; haptoglobin; serum amyloid A; surfactant protein D