title: Trabeculectomy with or without Anterior Chamber Maintainer: A Study on Intraocular Pressure, Endothelial Cells, and Central Corneal Thickness.
abstract: OBJECTIVE
  To compare the impact of trabeculectomy and trabeculectomy with an anterior chamber (AC) maintainer on intraocular pressure (IOP), endothelial cell density (ECD), and central corneal thickness (CCT) in patients with primary open angle glaucoma (POAG).
  
  
  METHODS
  The two groups consisted of 36 (trabeculectomy, Group A) and 42 (trabeculectomy with AC maintainer, Group B) patients with POAG. IOP, CCT, and ECD were measured one day prior to surgery, one month, six months, and 12 months postoperatively.
  
  
  RESULTS
  No complications were observed. The mean decrease of mean IOP from baseline to 12 months was statistically significant for both groups (all p < 0.0001), but more significant in Group B (p = 0.01). ECD decrease was significant in both Groups (all p < 0.01), but more significant in Group A (p < 0.0001). CCT decrease was also greater in Group A (p < 0.0001). The surgical procedure's duration was significantly longer in Group B than in Group A (p < 0.0001).
  
  
  CONCLUSIONS
  Both techniques seem to be effective and safe options for patients with POAG. Using an AC maintainer might add some safety for the ECD and a bit greater IOP reduction; however, the classic technique, which is of less complexity and less time-consuming, has comparable results.
authors.affiliation: a First Department of Ophthalmology , University of Athens , Athens , Greece.
authors.forename: Marilita M
authors.initials: MM
authors.lastname: Moschos
authors.affiliation: b Department of Ophthalmology , Geneva University Hospitals , Geneva , Switzerland.
authors.forename: Georgios D
authors.initials: GD
authors.lastname: Panos
authors.affiliation: a First Department of Ophthalmology , University of Athens , Athens , Greece.
authors.forename: Anastasios
authors.initials: A
authors.lastname: Lavaris
authors.affiliation: a First Department of Ophthalmology , University of Athens , Athens , Greece.
authors.forename: Konstantinos
authors.initials: K
authors.lastname: Droutsas
authors.affiliation: b Department of Ophthalmology , Geneva University Hospitals , Geneva , Switzerland.
authors.forename: Zisis
authors.initials: Z
authors.lastname: Gatzioufas
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D000867:Anterior Chamber / Q000601:surgery*; D003315:Cornea / Q000473:pathology*; D042783:Endothelial Cells / Q000473:pathology; D004728:Endothelium, Corneal / Q000473:pathology*; D005260:Female; D005902:Glaucoma, Open-Angle / Q000473:pathology / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology*; D008297:Male; D008875:Middle Aged; D014130:Trabeculectomy / Q000009:adverse effects / Q000379:methods*
keywords: Anterior chamber maintainer; central corneal thickness; endothelial cell density; glaucoma; trabeculectomy