title: Imaging of MELAS.
abstract: Mitochondrial diseases are multisystem disorders that frequently involve the central nervous system. The clinical presentation of these disorders may be challenging to differentiate from cerebrovascular disorders. Various imaging techniques are now available that provide a wide range of imaging modalities during initial clinical evaluation and throughout the disease course. Recent technological advancements have introduced advanced neuroimaging modalities that provide detailed information of metabolic disorders at the tissue level. Imaging findings, though diverse, usually have characteristic features that support differentiating these disorders from vascular syndromes. This article provides an overview of various neuroimaging modalities available along with the advent of new imaging techniques being utilized in these disorders.
authors.affiliation: Department of Neurology, Vascular Neurology Fellow, UCLA, Los Angeles, CA, USA.
authors.forename: Konark
authors.initials: K
authors.lastname: Malhotra
authors.affiliation: Neurovascular Imaging Research Core, Neuroscience Research Building, 635 Charles E Young Drive South, Suite 225, Los Angeles, CA, 90095-7334, USA. davidliebeskind@yahoo.com.
authors.forename: David S
authors.initials: DS
authors.lastname: Liebeskind
mesh_terms: D006801:Humans; D017241:MELAS Syndrome / Q000175:diagnosis*; D059906:Neuroimaging / Q000379:methods*
keywords: MELAS; MRI; Mitochondrial myopathy; Stroke-like episodes