title: Use of a Nonexercise Estimate for Prestroke Peak Vo2During the Acute Stroke Hospital Stay.
abstract: OBJECTIVE
  For individuals with acute stroke, it is difficult to conduct an exercise test to assess peak oxygen consumption (peak Vo2). Therefore, the purpose of this study was to use a clinically feasible tool for assessing prestroke peak Vo2using a nonexercise estimation equation to test whether estimated prestroke peak Vo2was related to the functional outcome measures at discharge from the hospital in individuals after an acute stroke. We hypothesized that the estimated prestroke peak Vo2would be significantly related to discharge Physical Performance Test (PPT), 6-minute walk test (6MWT), and lower extremity Fugl-Meyer (LEFM) assessment.
  
  
  METHODS
  Estimated prestroke peak Vo2was calculated using a previously validated prediction equation using the following variables: body mass index, age, sex, resting heart rate, and a self-reported measure of physical activity. Outcome measures were assessed 4 days after enrollment or immediately before discharge (whichever occurred first).
  
  
  RESULTS
  Thirty-four participants (mean age = 56.0, SD = 12.6 years; 20 men) with acute stroke were enrolled within 48 hours of admission. For all individuals, mean estimated prestroke peak Vo2was 27.3 (SD = 7.4) mL·kg-1·min-1and had a weak, nonsignificant relationship with the PPT (r = 0.19;P= .28), 6MWT (r = 0.10;P= .56), and LEFM (r = 0.32;P= .06). However, when considering sex, women, but not men, had a significant relationship with LEFM (r = 0.73;P= .005) and moderate but nonsignificant relationship with PPT (r = 0.53;P= .06) and 6MWT (r = 0.47;P= .10).
  
  
  CONCLUSIONS
  Within 48 hours of stroke admission, we were able to administer a nonexercise equation to estimate prestroke peak Vo2. For the entire sample, functional measures conducted at discharge were not related to estimated prestroke peak Vo2. However, when considering sex, the relationship between prestroke Vo2and the functional measures was strengthened.
authors.affiliation: Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Anna E
authors.initials: AE
authors.lastname: Mattlage
authors.affiliation: Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Sara A
authors.initials: SA
authors.lastname: Redlin
authors.affiliation: Department of Neurology, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Lee R
authors.initials: LR
authors.lastname: Rosterman
authors.affiliation: Department of Radiology, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Nick
authors.initials: N
authors.lastname: Harn
authors.affiliation: Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Jason-Flor V
authors.initials: JV
authors.lastname: Sisante
authors.affiliation: Department of Neurology, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Michael G
authors.initials: MG
authors.lastname: Abraham
authors.affiliation: Department of Physical Therapy and Rehabilitation Science, University of Kansas Medical Center, Kansas City, KS.
authors.forename: Sandra A
authors.initials: SA
authors.lastname: Billinger
keywords: acute stroke; estimated peak Vo2; functional performance; nonexercise Vo2 estimate