title: Redundancy and specificity in jasmonate signalling.
abstract: Jasmonates (JAs) are essential phytohormones regulating plant development and environmental adaptation. Many components of the JA-signalling pathway have been identified. However, our insight into the mechanisms by which a single bioactive JA hormone can regulate a myriad of physiological processes and provide specificity in the response remains limited. Recent findings on molecular components suggest that, despite apparent redundancy, specificity is achieved by (1) distinct protein-protein interactions forming unique JAZ/transcription factor complexes, (2) discrete spatiotemporal expression of specific components, (3) variable hormone thresholds for the formation of multiple JA receptor complexes and (4) integration of several signals by JA-pathway components. The molecular modularity that is thereby created enables a single bioactive hormone to specifically modulate multiple JA-outputs in response to different environmental and developmental cues.
authors.affiliation: Department of Plant Molecular Genetics, National Centre for Biotechnology (CNB-CSIC), 28049 Madrid, Spain.
authors.forename: Andrea
authors.initials: A
authors.lastname: Chini
authors.affiliation: Department of Plant Molecular Genetics, National Centre for Biotechnology (CNB-CSIC), 28049 Madrid, Spain.
authors.forename: Selena
authors.initials: S
authors.lastname: Gimenez-Ibanez
authors.affiliation: Department of Plant Systems Biology, Flanders Institute for Biotechnology (VIB), Technologiepark 927, B-9052 Gent, Belgium; Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, B-9052 Gent, Belgium.
authors.forename: Alain
authors.initials: A
authors.lastname: Goossens
authors.affiliation: Department of Plant Molecular Genetics, National Centre for Biotechnology (CNB-CSIC), 28049 Madrid, Spain. Electronic address: rsolano@cnb.csic.es.
authors.forename: Roberto
authors.initials: R
authors.lastname: Solano
mesh_terms: D017360:Arabidopsis / Q000235:genetics / Q000502:physiology*; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D003517:Cyclopentanes / Q000378:metabolism*; D018506:Gene Expression Regulation, Plant; D054883:Oxylipins / Q000378:metabolism*; D010937:Plant Growth Regulators / Q000378:metabolism*; D015398:Signal Transduction
chemical_list: D029681:Arabidopsis Proteins; D003517:Cyclopentanes; D054883:Oxylipins; D010937:Plant Growth Regulators; C011006:jasmonic acid