title: Weight loss among women and men in the ASPIRE-VA behavioral weight loss intervention trial.
abstract: Weight loss was examined among women and men veterans in a clinical trial comparing Aspiring for Lifelong Health (ASPIRE), a "small changes" weight loss program using either mixed-sex group-visit or telephone-based coaching, to MOVE!(®) , the usual mixed-sex group-based program.
  
  
  
  Linear mixed-effects models were used to calculate adjusted percent weight change at 12 months by sex and compare outcomes across arms within sex.
  
  
  
  Analyses included 72 women (ASPIRE-Phone = 26; ASPIRE-Group = 26; MOVE! = 20) and 409 men (ASPIRE-Phone = 136; ASPIRE-Group = 134; MOVE! = 139). At 12 months, women displayed significant weight loss from baseline in ASPIRE-Group (-2.6%) and MOVE! (-2.7%), but not ASPIRE-Phone (+0.2%). Between-arm differences in weight change among women were: ASPIRE-Group versus ASPIRE-Phone, -2.8% (P = 0.15); MOVE! versus ASPIRE-Phone, -2.8% (P = 0.20); and ASPIRE-Group versus MOVE!, 0.0% (P = 1.0). At 12 months, men lost significant weight from baseline across arms (ASPIRE-Phone, -1.5%; ASPIRE-Group, -2.5%; MOVE!, -1.0%). Between-arm differences in weight change among men were: ASPIRE-Group versus ASPIRE-Phone, -0.9% (P = 0.23); MOVE! versus ASPIRE-Phone, +0.5% (P = 0.76); ASPIRE-Group versus MOVE!, -1.5% (P = 0.03).
  
  
  
  Mixed-sex, group-based programs can result in weight loss for both women and men veterans.
authors.affiliation: Center for Healthcare Organization and Implementation Research, Bedford VA Medical Center, Bedford, Massachusetts, USA.|Section of Endocrinology, Diabetes and Metabolism, Boston University School of Medicine, Boston, Massachusetts, USA.
authors.forename: Varsha
authors.initials: V
authors.lastname: Vimalananda
authors.affiliation: VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
authors.forename: Laura
authors.initials: L
authors.lastname: Damschroder
authors.affiliation: VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
authors.forename: Carol A
authors.initials: CA
authors.lastname: Janney
authors.affiliation: VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
authors.forename: David
authors.initials: D
authors.lastname: Goodrich
authors.affiliation: Center for Statistical Consultation and Research, University of Michigan, Ann Arbor, Michigan, USA.
authors.forename: H Myra
authors.initials: HM
authors.lastname: Kim
authors.affiliation: VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Holleman
authors.affiliation: VA Center for Clinical Management Research, VA Ann Arbor Healthcare System, Ann Arbor, Michigan, USA.
authors.forename: Leah
authors.initials: L
authors.lastname: Gillon
authors.affiliation: Department of Psychology, East Carolina University, Greenville, North Carolina, USA.
authors.forename: Lesley
authors.initials: L
authors.lastname: Lutes
mesh_terms: D000328:Adult; D001521:Behavior Therapy; D001835:Body Weight; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000628:therapy*; D013689:Telephone; D014728:Veterans; D058014:Veterans Health; D015431:Weight Loss; D061217:Weight Reduction Programs