title: Chronic Invasive Pulmonary Aspergillosis in Two Cats with Diabetes Mellitus.
abstract: Human patients with diabetes mellitus are at increased risk of fungal infections. Diabetes mellitus has also been implicated as a predisposing factor in the establishment of fungal lung infections in cats. Two diabetic cats of different origins presented with severe acute respiratory conditions that resulted in their death. At necropsy examination there was friable, black material in the main bronchi that obstructed the bronchial lumina. Microscopical examination of the lungs revealed the presence of pneumonia, calcium oxalate crystals and a large quantity of fungal hyphae and conidial heads. Fungal infection was confirmed with Grocott's methenamine silver stain. The results of the mycology analysis were compatible with Aspergillus section Nigri.
authors.affiliation: Department of Veterinary Pathology, Brazil.
authors.forename: R V
authors.initials: RV
authors.lastname: Leite-Filho
authors.affiliation: Department of Veterinary Pathology, Brazil.
authors.forename: G
authors.initials: G
authors.lastname: Fredo
authors.affiliation: Veterinary Clinic Hospital, Brazil.
authors.forename: C G
authors.initials: CG
authors.lastname: Lupion
authors.affiliation: Department of Veterinary Mycology, Federal University of Rio Grande do Sul, 9090 Av. Bento Gonçalves, 9090 Pr. 42505, Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: A
authors.initials: A
authors.lastname: Spanamberg
authors.affiliation: Veterinary Clinic Hospital, Brazil.
authors.forename: G
authors.initials: G
authors.lastname: Carvalho
authors.affiliation: Department of Veterinary Mycology, Federal University of Rio Grande do Sul, 9090 Av. Bento Gonçalves, 9090 Pr. 42505, Porto Alegre, Rio Grande do Sul, Brazil.
authors.forename: L
authors.initials: L
authors.lastname: Ferreiro
authors.affiliation: Department of Veterinary Pathology, Brazil.
authors.forename: D
authors.initials: D
authors.lastname: Driemeier
authors.affiliation: Department of Veterinary Pathology, Brazil.
authors.forename: S P
authors.initials: SP
authors.lastname: Pavarini
authors.affiliation: Department of Veterinary Pathology, Brazil. Electronic address: lusonne@yahoo.com.br.
authors.forename: L
authors.initials: L
authors.lastname: Sonne
mesh_terms: D000818:Animals; D002371:Cat Diseases; D002415:Cats; D003920:Diabetes Mellitus / Q000662:veterinary*; D005260:Female; D055744:Invasive Pulmonary Aspergillosis / Q000662:veterinary*; D008297:Male
keywords: Aspergillus section Nigri; cat; diabetes mellitus; invasive aspergillosis