title: Asymmetric Construction of 2,3-Dihydroisoxazoles via an Organocatalytic Formal [3 + 2] Cycloaddition of Enynes with N-Hydroxylamines.
abstract: An organocatalytic asymmetric formal [3 + 2] cycloaddition of enynones with N-hydroxylamines has been described. A newly designed multifunctional organocatalyst was found to be highly effective, and the method allowed the synthesis of a variety of 2,3-dihydroisoxazoles in good yields with excellent enantioselectivity.
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University , Shanghai 200062, China.
authors.forename: Wenbo
authors.initials: W
authors.lastname: Li
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University , Shanghai 200062, China.
authors.forename: Xiuzhao
authors.initials: X
authors.lastname: Yu
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University , Shanghai 200062, China.
authors.forename: Zhenting
authors.initials: Z
authors.lastname: Yue
authors.affiliation: Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University , Shanghai 200062, China.|State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry , Shanghai 200032, China.
authors.forename: Junliang
authors.initials: J
authors.lastname: Zhang