title: Comparison of Keyes Punch Biopsy Instrument with Cervical Punch Biopsy Forceps for Diagnosing Cervical Lesions.
abstract: OBJECTIVE
  To assess the feasibility and efficacy of Keyes punch biopsy instrument (KP) in diagnosing cervical lesions and compare it with cervical punch biopsy forceps (CP).
  
  
  METHODS
  75 women having satisfactory colposcopy with abnormal transformation zone were included and paired colposcopic directed biopsies were taken using KP followed by CP from the same target area.
  
  
  RESULTS
  It was feasible in all cases to take cervical biopsy with KP after increasing its effective length. The volume of gross specimen obtained by KP was less than CP (0.076 ± 0.097 vs. 0.101 ± 0.156 cm3, p = 0.061), however on microscopic examination, mean length and mean depth of tissue in KP was greater than CP by 0.06 mm (p = 0.810) and 0.14 mm (p = 0.634) respectively. Exact agreement was found with the final surgical specimen in 42% of cases in both the biopsy forceps.
  
  
  CONCLUSIONS
  KP is almost at par with CP for diagnosing preinvasive cervical lesions and is a useful adjunct to the existing armamentarium of biopsy forceps.
authors.affiliation: Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India.
authors.forename: Natasha
authors.initials: N
authors.lastname: Tyagi
authors.forename: Amita
authors.initials: A
authors.lastname: Suneja
authors.forename: Kiran
authors.initials: K
authors.lastname: Mishra
authors.forename: Sandhya
authors.initials: S
authors.lastname: Jain
authors.forename: Neelam Bala
authors.initials: NB
authors.lastname: Vaid
authors.forename: Kiran
authors.initials: K
authors.lastname: Guleria
mesh_terms: D000328:Adult; D001706:Biopsy / Q000295:instrumentation*; D003127:Colposcopy / Q000592:standards*; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D009772:Obstetrical Forceps / Q000592:standards; D013525:Surgical Instruments / Q000592:standards*; D002577:Uterine Cervical Diseases / Q000175:diagnosis*; D002583:Uterine Cervical Neoplasms