title: Core functionalization of semi-crystalline polymeric cylindrical nanoparticles using photo-initiated thiol-ene radical reactions.
abstract: Sequential ring-opening and reversible addition-fragmentation chain transfer (RAFT) polymerization was used to form a triblock copolymer of tetrahydropyran acrylate (THPA), 5-methyl-5-allyloxycarbonyl-1,3-dioxan-2-one (MAC) and l-lactide. Concurrent deprotection of the THPA block and crystallization-driven self-assembly (CDSA) was undertaken and allowed for the formation of cylindrical micelles bearing allyl handles in a short outer core segment. These handles were further functionalized by different thiols using photo-initiated thiol-ene radical reactions to demonstrate that the incorporation of an amorphous PMAC block within the core does not disrupt CDSA and can be used to load the cylindrical nanoparticles with cargo.
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk.
authors.forename: Liang
authors.initials: L
authors.lastname: Sun
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk.
authors.forename: Anaïs
authors.initials: A
authors.lastname: Pitto-Barry
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk.
authors.forename: Anthony W
authors.initials: AW
authors.lastname: Thomas
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk.
authors.forename: Maria
authors.initials: M
authors.lastname: Inam
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk.
authors.forename: Kay
authors.initials: K
authors.lastname: Doncom
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk; Department of Materials Engineering , Monash University , Clayton , Victoria 3800 , Australia.
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Dove
authors.affiliation: Department of Chemistry , University of Warwick , Gibbet Hill Road , Coventry , CV4 7AL , UK . Email: a.p.dove@warwick.ac.uk ; Email: r.k.o-reilly@warwick.ac.uk.
authors.forename: Rachel K
authors.initials: RK
authors.lastname: O'Reilly