title: Immunomodulators in the Treatment of Nasal Polyposis.
abstract: The inflammatory mechanisms that contribute to chronic rhinosinusitis with nasal polyps (CRSwNP) are complex. In the past, medical options for treating CRSwNP have been limited. Emerging classes of immunomodulators such as omalizumab, anti-leukotrienes, anti-IL-4, anti-IL-5, and recognition of the modulating effects of macrolides have shown promising results in the treatment of CRSwNP. Ultimately, large randomized controlled trials are necessary to establish the efficacy of these medications but for now, the area of medical immunomodulators remains an exciting frontier.
authors.forename: Ashleigh A
authors.initials: AA
authors.lastname: Halderman
authors.forename: Andrew P
authors.initials: AP
authors.lastname: Lane
mesh_terms: D002908:Chronic Disease; D006801:Humans; D007155:Immunologic Factors / Q000627:therapeutic use*; D009298:Nasal Polyps / Q000188:drug therapy*; D012220:Rhinitis / Q000188:drug therapy; D012852:Sinusitis / Q000188:drug therapy
chemical_list: D007155:Immunologic Factors