title: Cytokines in B-Cell Chronic Lymphocytic Leukemia.
abstract: The pleomorphic action of different cytokines in regulating the growth and proliferation of normal B- and T-lymphocyte populations is becoming progressively more apparent. Thus, the possibility that some cytokines, either alone or in variable combination, may play a role in different lymphoproliferative disorders has been increasingly suggested and potential autocrine or paracrine loops hypothesized. Here, we shall discuss some of the known B-cell growth factors which have been postulated to be involved in the hematological progression, clinical course and complications in B-cell lymphocytic leukemia.
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: R
authors.initials: R
authors.lastname: Foa
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: A G
authors.initials: AG
authors.lastname: Tos
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: P
authors.initials: P
authors.lastname: Francia di Celle
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Carbone
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: D
authors.initials: D
authors.lastname: Marchis
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: F
authors.initials: F
authors.lastname: Vischia
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Cignetti
authors.affiliation: a Dipartimento di Scienze Biomediche ed Oncologia Umana, Sezione di Clinica Medica, and Centro CNR "Immunogenetica ed Istocompatibilitá", University of Torino, Italy.
authors.forename: A
authors.initials: A
authors.lastname: Guarini
keywords: B-CLL; Cytokines; lymphocytic leukemia