title: Biomarkers in Pediatric Cardiac Critical Care.
abstract: In this review, we discuss the physiology, pathophysiology, and clinical role of troponin, lactate, and B-type natriuretic peptide in the assessment and management of children with critical cardiac disease.
  
  
  
  MEDLINE, PubMed.
  
  
  
  Lactate, troponin, and B-type natriuretic peptide continue to be valuable biomarkers in the assessment and management of critically ill children with cardiac disease. However, the use of these markers as a single measurement is handicapped by the wide variety of clinical scenarios in which they may be increased. The overall trend may be more useful than any single level with a persistent or rising value of more importance than an elevated initial value.
authors.affiliation: 1Department of Pediatrics, Section of Critical Care Medicine, David Geffen School of Medicine, University of California Los Angeles, Children's Hospital of Orange County Orange, CA. 2Section of Critical Care Medicine, Royal Children's Hospital, Melbourne, Parkville, VIC, Australia.
authors.forename: Michele
authors.initials: M
authors.lastname: Domico
authors.forename: Meredith
authors.initials: M
authors.lastname: Allen
mesh_terms: D015415:Biomarkers / Q000032:analysis*; D002648:Child; D003422:Critical Care / Q000379:methods*; D006331:Heart Diseases / Q000175:diagnosis*; D006801:Humans; D015278:Intensive Care Units, Pediatric
chemical_list: D015415:Biomarkers