title: Determination of haloacetic acids in water using layered double hydroxides as a sorbent in dispersive solid-phase extraction followed by liquid chromatography with tandem mass spectrometry.
abstract: In the present study, highly efficient and simple dispersive solid-phase extraction procedure for the determination of haloacetic acids in water samples has been established. Three different types of layered double hydroxides were synthesized and used as a sorbent in dispersive solid-phase extraction. Due to the interesting behavior of layered double hydroxides in an acidic medium (pH˂4), the analyte elution step was not needed; the layered double hydroxides are simply dissolved in acid immediately after extraction to release the analytes which are then directly introduced into a liquid chromatography with tandem mass spectrometry system for analysis. Several dispersive solid-phase extraction parameters were optimized to increase the extraction efficiency of haloacetic acids such as temperature, extraction time and pH. Under optimum conditions, good linearity was achieved over the concentration range of 0.05-100 μg/L with detection limits in the range of 0.006-0.05 μg/L. The relative standard deviations were 0.33-3.64% (n = 6). The proposed method was applied to different water samples collected from a drinking water plant to determine the concentrations of haloacetic acids.
authors.affiliation: Department of Chemistry, King Fahd University of Petroleum and minerals, Dhahran, Saudi Arabia.
authors.forename: Abdulnaser
authors.initials: A
authors.lastname: Alsharaa
authors.affiliation: Department of Chemistry, King Fahd University of Petroleum and minerals, Dhahran, Saudi Arabia.
authors.forename: Muhammad
authors.initials: M
authors.lastname: Sajid
authors.affiliation: Department of Chemistry, King Fahd University of Petroleum and minerals, Dhahran, Saudi Arabia. cbasheer@kfupm.edu.sa.
authors.forename: Chanbasha
authors.initials: C
authors.lastname: Basheer
authors.affiliation: Department of Chemistry, King Fahd University of Petroleum and minerals, Dhahran, Saudi Arabia.
authors.forename: Khalid
authors.initials: K
authors.lastname: Alhooshani
authors.affiliation: Department of Chemistry, National University of Singapore, Singapore.
authors.forename: Hian Kee
authors.initials: HK
authors.lastname: Lee
mesh_terms: D000327:Adsorption; D002853:Chromatography, Liquid; D060766:Drinking Water / Q000737:chemistry*; D006863:Hydrogen-Ion Concentration; D006878:Hydroxides / Q000737:chemistry*; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D053719:Tandem Mass Spectrometry; D014874:Water Pollutants, Chemical / Q000737:chemistry / Q000302:isolation & purification*
chemical_list: D060766:Drinking Water; D006878:Hydroxides; D014874:Water Pollutants, Chemical
keywords: Dispersive solid-phase extraction; Haloacetic acids; Layered double hydroxides; Liquid chromatography-tandem mass spectrometry