title: Tuning the MYC response.
abstract: Altering the ability of the MYC transcription factor to bind to individual genes can customize the global gene expression output of cells.
authors.affiliation: Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
authors.forename: Ying
authors.identifier: 0000-0003-0674-2438
authors.initials: Y
authors.lastname: Zheng
authors.affiliation: Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, United States.
authors.forename: David
authors.identifier: 0000-0002-7616-922X
authors.initials: D
authors.lastname: Levens
mesh_terms: D015870:Gene Expression; D011401:Promoter Regions, Genetic; D016271:Proto-Oncogene Proteins c-myc / Q000235:genetics*; D014157:Transcription Factors / Q000235:genetics
chemical_list: D016271:Proto-Oncogene Proteins c-myc; D014157:Transcription Factors
keywords: ChIP-sequencing; MIZ1; MYC; WDR5; cancer biology; cell biology; human; mathematical modeling; mouse; promoter affinity