title: A systematic review on the impact of psychotropic drugs on electroencephalogram waveforms in psychiatry.
abstract: OBJECTIVE
  It is known that psychotropic medications have an impact on the readings found in Electroencephalogram (EEG). In the field of psychiatry, there are several psychotropics utilized by clinicians. This review seeks to investigate all the available data for psychotropic drugs and their impact on EEG changes.
  
  
  METHODS
  A systematic review of all the published and ongoing literature was conducted via PubMed. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method was used for each search. Key words for searches include 'EEG and Psychotropics', 'EEG and Mood Stabilizers', 'EEG and Clozapine', 'EEG and Bupropion', 'EEG and SSRI', 'EEG and Lamotrigine', 'EEG and Carbamazepine', 'EEG and Lithium' and 'EEG and Valproate', 'EEG and Haloperidol', 'EEG and Aripiprazole', 'EEG and Methylphenidate', 'EEG and Topiramate', 'EEG and Gabapentin' and 'EEG and Oxcarbamazepine'. After applying the inclusion criteria, 201 articles were eligible and reviewed.
  
  
  RESULTS
  Following an extensive review of selected studies from the 201 articles, the studies indicate that each of the psychotropic medications reviewed impact alpha, beta, delta and theta waves independently and differently from each other. Additionally, certain medications, particularly haloperidol and valproic acid, have dissimilar results exemplified in all waveforms.
  
  
  CONCLUSIONS
  This PRISMA systematic review illustrates that while there is available data on psychotropic medications and their proposed effect on EEG activity, further research is needed to confirm these findings to help allow clinical correlations to be made between the patient's response and the psychotropic agent.
authors.affiliation: a Department of Psychiatry, Hofstra Northwell Health , Staten Island University Hospital , Staten Island , NY , USA.
authors.forename: Rohit
authors.initials: R
authors.lastname: Aiyer
authors.affiliation: a Department of Psychiatry, Hofstra Northwell Health , Staten Island University Hospital , Staten Island , NY , USA.
authors.forename: Vladan
authors.initials: V
authors.lastname: Novakovic
authors.affiliation: b Department of Anesthesiology, Family Medicine & Pharmacology, Rush Medical College , North Shore University Health System Evanston and Skokie Hospital , Chicago , IL , USA.
authors.forename: Robert L
authors.initials: RL
authors.lastname: Barkin
mesh_terms: D004569:Electroencephalography / Q000187:drug effects* / Q000379:methods; D006801:Humans; D001523:Mental Disorders / Q000175:diagnosis / Q000188:drug therapy; D011619:Psychotropic Drugs / Q000145:classification / Q000494:pharmacology
chemical_list: D011619:Psychotropic Drugs
keywords: EEG; Electroencephalogram; Psychotropics; antidepressants; antipsychotics; mood stabilizers; stimulants