title: Antisuperbug Cotton Fabric with Excellent Laundering Durability.
abstract: Multidrug-resistant superbugs are currently a severe threat to public health. Here, we report a novel kind of antisuperbug material prepared by irradiation induced graft polymerization of 1-butyl-3-vinyl imidazole chloride onto cotton fabric. The reduction of superbugs on this fabric is higher than 99.9%. Attributed to the strong covalent bonding between the graft chains and the cellulose macromolecules, the antisuperbug performance did not decrease even after 150 equiv of domestic laundering cycles. Covalent bonding also prevented the release of the antibacterial groups during application and guarantees the safety of the material, which was proved by animal skin irritation and acute oral toxicity tests.
authors.forename: Ming
authors.initials: M
authors.lastname: Yu
authors.forename: Ziqiang
authors.initials: Z
authors.lastname: Wang
authors.forename: Min
authors.initials: M
authors.lastname: Lv
authors.affiliation: Institute for Disease Control and Prevention, Academy of Military Medical Sciences , Beijing 100036, P. R. China.
authors.forename: Rongzhang
authors.initials: R
authors.lastname: Hao
authors.affiliation: Institute for Disease Control and Prevention, Academy of Military Medical Sciences , Beijing 100036, P. R. China.
authors.forename: Rongtao
authors.initials: R
authors.lastname: Zhao
authors.affiliation: Institute for Disease Control and Prevention, Academy of Military Medical Sciences , Beijing 100036, P. R. China.
authors.forename: Lihua
authors.initials: L
authors.lastname: Qi
authors.forename: Shima
authors.initials: S
authors.lastname: Liu
authors.forename: Chuhong
authors.initials: C
authors.lastname: Yu
authors.forename: Bowu
authors.initials: B
authors.lastname: Zhang
authors.forename: Chunhai
authors.initials: C
authors.lastname: Fan
authors.forename: Jingye
authors.initials: J
authors.lastname: Li
keywords: antibiotic resistance; antisuperbug cotton fabric; covalent bonding; laundering durability; radiation induced graft polymerization