title: Diverse N-Heterocyclic Ring Systems via Aza-Heck Cyclizations of N-(Pentafluorobenzoyloxy)sulfonamides.
abstract: Aza-Heck cyclizations initiated by oxidative addition of Pd(0) -catalysts into the N-O bond of N-(pentafluoro-benzoyloxy)sulfonamides are described. These studies, which encompass only the second class of aza-Heck reaction developed to date, provide direct access to diverse N-heterocyclic ring systems.
authors.affiliation: School of Chemistry, University of Bristol, Bristol, BS8 1TS, United Kingdom.
authors.forename: Ian R
authors.initials: IR
authors.lastname: Hazelden
authors.affiliation: School of Chemistry, University of Bristol, Bristol, BS8 1TS, United Kingdom.
authors.forename: Xiaofeng
authors.initials: X
authors.lastname: Ma
authors.affiliation: Pharmaceutical Technology & Development, AstraZeneca, Charter Way, Macclesfield, SK10 2NA, United Kingdom.
authors.forename: Thomas
authors.initials: T
authors.lastname: Langer
authors.affiliation: School of Chemistry, University of Bristol, Bristol, BS8 1TS, United Kingdom.
authors.forename: John F
authors.initials: JF
authors.lastname: Bower
keywords: N-heterocycles; aza-Heck reaction; cascade reactions; palladium