title: Detection of kobuvirus RNA in Japanese domestic dogs.
abstract: To investigate whether kokuvirus is present in Japanese dogs, we examined the fecal samples obtained from 94 diarrheal household dogs and 50 clinically healthy kenneled dogs by RT-PCR. The gene was detected in 37.2% and 48.0% in the former and the latter, respectively, suggesting that canine kobuvirus (CaKoV) is circulating among Japanese dogs. From the result of the latter, however, CaKoV may not be a primary pathogen. Furthermore, all gene-positive dogs were purebreds aged four months or younger. This finding suggests that CaKoV endemic is confined in multi-dog environments, and the dogs have a strong age-dependent resistance to CaKoV.
authors.affiliation: Veterinary Diagnostic Laboratory, Marupi Lifetech Co., Ltd., 103 Fushiocho, Ikeda, Osaka 563-0011, Japan.
authors.forename: Takehisa
authors.initials: T
authors.lastname: Soma
authors.forename: Makoto
authors.initials: M
authors.lastname: Matsubayashi
authors.forename: Kazumi
authors.initials: K
authors.lastname: Sasai
mesh_terms: D000367:Age Factors; D000818:Animals; D003967:Diarrhea / Q000453:epidemiology / Q000662:veterinary / Q000821:virology; D004283:Dog Diseases / Q000453:epidemiology / Q000821:virology*; D004285:Dogs / Q000821:virology*; D005243:Feces / Q000821:virology; D007564:Japan / Q000453:epidemiology; D052699:Kobuvirus / Q000302:isolation & purification*; D010850:Picornaviridae Infections / Q000453:epidemiology / Q000662:veterinary*; D012367:RNA, Viral / Q000302:isolation & purification
chemical_list: D012367:RNA, Viral