title: Repeatability of selective laser trabeculoplasty for open-angle glaucoma.
abstract: BACKGROUND
  To analyze the results of repeat selective laser trabeculoplasty (SLT).
  
  
  METHODS
  
  
  
  METHODS
  participants with primary or secondary open-angle glaucoma (excluding uveitic) who had undergone SLT 360° (SLT 1) with diminution of response over time followed by repeat SLT 360° (SLT 2). Six months of follow-up were required and at least 6 months in between SLT 1 and 2. The main outcome measures were IOP reduction at 6 and 12 months and a comparison of the response between SLT 1 and 2.
  
  
  RESULTS
  One hundred thirty-seven patients met the inclusion criteria. If only one eye had repeat treatment, that eye was chosen; if both eyes qualified, one was chosen at random. The baseline intraocular pressure (IOP) for SLT 1 = 20.3+/- 5.2 mmHg and SLT 2 = 19.4 +/- 5.0 was reduced to 16.4 +/- 3.9 and 16.7 +/- 4.7 at 1 year, respectively (p < .001). Medication use was not significantly changed, and was 2.2 +/- 1.2 at baseline for SLT 1 and 2.1 +/- 1.3 for SLT 2, and at 1 year was 1.9 +/- 1.3 and 2.2 +/- 1.2, respectively. A subanalysis of 62 patients matched for equivalent baselines showed a baseline IOP = 18.7 +/- 3.8 for SLT 1 and 18.7 +/- 3.5 for SLT 2, reduced to 16.0 +/- 4.3 and 15.3 +/- 3.8 at 1 year (p < .001).
  
  
  CONCLUSIONS
  Repeat SLT laser (360-degree treatment, followed by a loss of effect over time, then a second 360-degree treatment) in this population resulted in IOP lowering similar to that of the initial treatment.
authors.affiliation: Department of Ophthalmology, David Geffen School of Medicine at UCLA, Doheny Eye Institute, 800 Fairmount Avenue, Suite 215, Pasadena, Los Angeles, CA, 91105, USA. bfrancis@doheny.org.
authors.forename: Brian A
authors.initials: BA
authors.lastname: Francis
authors.affiliation: Department of Ophthalmology, University of Pittsburgh, School of Medicine, Pittsburgh, PA, USA.
authors.forename: Nils
authors.initials: N
authors.lastname: Loewen
authors.affiliation: Department of Ophthalmology, Thomas Jefferson School of Medicine, Wills Eye Institute, Philadelphia, PA, USA.
authors.forename: Bryan
authors.initials: B
authors.lastname: Hong
authors.affiliation: Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
authors.forename: Laurie
authors.initials: L
authors.lastname: Dustin
authors.affiliation: Department of Ophthalmology, Stony Brook University, Stony Brook, NY, USA.
authors.forename: Kevin
authors.initials: K
authors.lastname: Kaplowitz
authors.affiliation: North Bay Eye Associates, Sonoma County, CA, USA.
authors.forename: Robert
authors.initials: R
authors.lastname: Kinast
authors.affiliation: Glaucoma Center of San Francisco, San Francisco, CA, USA.
authors.forename: Jason
authors.initials: J
authors.lastname: Bacharach
authors.affiliation: Glaucoma Center of San Francisco, San Francisco, CA, USA.
authors.forename: Sunita
authors.initials: S
authors.lastname: Radhakrishnan
authors.affiliation: Glaucoma Center of San Francisco, San Francisco, CA, USA.
authors.forename: Andrew
authors.initials: A
authors.lastname: Iwach
authors.affiliation: Research and Education Group, San Francisco, CA, USA.
authors.forename: Lidiya
authors.initials: L
authors.lastname: Rudavska
authors.affiliation: Wills Eye Hospital, Thomas Jefferson University Medical School, Philadelphia, PA, USA.
authors.forename: Parul
authors.initials: P
authors.lastname: Ichhpujani
authors.affiliation: Wills Eye Hospital, Thomas Jefferson University Medical School, Philadelphia, PA, USA.
authors.forename: L Jay
authors.initials: LJ
authors.lastname: Katz
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000959:Antihypertensive Agents / Q000627:therapeutic use; D005260:Female; D005902:Glaucoma, Open-Angle / Q000188:drug therapy / Q000503:physiopathology / Q000601:surgery*; D006801:Humans; D007429:Intraocular Pressure / Q000502:physiology; D053685:Laser Therapy / Q000379:methods*; D008297:Male; D008875:Middle Aged; D012086:Reoperation; D015203:Reproducibility of Results; D012189:Retrospective Studies; D014065:Tonometry, Ocular; D014130:Trabeculectomy / Q000379:methods* / Q000592:standards
chemical_list: D000959:Antihypertensive Agents
keywords: Glaucoma; Laser; Repeat; Repeatability; Selective; Trabeculoplasty