title: A Case of a Newborn with Agenesis of the Corpus Callosum Complicated with Ocular Albinism.
abstract: OBJECTIVE
  To report a case of ocular albinism found in a newborn infant in whom agenesis of the corpus callosum (ACC) was indicated in utero.
  
  
  METHODS
  This study involved a female newborn who was delivered after a gestational period of 41 weeks. The patient was referred to the Obstetrics Department at Takatsuki Hospital, Takatsuki City, Japan, after the indication of ACC by magnetic resonance imaging (MRI) at a nearby clinic during the fetal period. At birth, the baby's weight was 2,590 g, and ACC and ventricular enlargement were found by cranial sonography and cranial MRI. While initial ophthalmic findings noted partial loss of pigmentation of the iris and hypopigmentation of broad areas of the fundus in both eyes, nystagmus was not observed. The patient's hair pigment was slightly diluted, and the color of her skin was slightly off-white. At 2 years after birth, obvious mental retardation was observed. With regard to other systemic findings, no apparent heart, kidney, or immune system abnormalities were found.
  
  
  CONCLUSIONS
  Although the patient in question is presently growing without any major systemic problems, it will be necessary in the future to pay attention to any changes in systemic and ophthalmic findings.
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan.
authors.forename: Michiko
authors.initials: M
authors.lastname: Miki
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan; Takatsuki Hospital, Takatsuki City, Japan.
authors.forename: Makiko
authors.initials: M
authors.lastname: Miyamoto
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan; Takatsuki Hospital, Takatsuki City, Japan.
authors.forename: Tatsuma
authors.initials: T
authors.lastname: Mitsutsuji
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan; Takatsuki Hospital, Takatsuki City, Japan.
authors.forename: Hiroko
authors.initials: H
authors.lastname: Watanabe
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan; Takatsuki Hospital, Takatsuki City, Japan.
authors.forename: Kazuhiro
authors.initials: K
authors.lastname: Shimizu
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan.
authors.forename: Junko
authors.initials: J
authors.lastname: Matsuo
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Tonari
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan.
authors.forename: Teruyo
authors.initials: T
authors.lastname: Kida
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan.
authors.forename: Jun
authors.initials: J
authors.lastname: Sugasawa
authors.affiliation: Department of Ophthalmology, Osaka Medical College, Takatsuki City, Japan.
authors.forename: Tsunehiko
authors.initials: T
authors.lastname: Ikeda
keywords: Agenesis of the corpus callosum; Hypopigmentation; Ocular albinism; Vici syndrome