title: Evaluation of Spontaneous Bone Regeneration after Enucleation of Large Cysts of the Jaws using Radiographic Computed Software.
abstract: BACKGROUND
  Spontaneous regeneration of bone is commonly seen in the small surgical defects caused by enucleation of cysts. However, in case of large surgical defects caused by the enucleation, spontaneous regeneration of bone is a rare phenomenon and it depends on factors, such as age of the patient, intact periosteum, and proper stabilization.
  
  
  METHODS
  The study included 16 patients, who reported to the department of oral and maxillofacial surgery with the complaint of pain and swelling in the jaws diagnosed as cyst. The sample included equal numbers of male and female subjects aged between 15 and 40 years. Panoramic radiographs were taken pre- and postoperatively on day 2 of the enucleation. The dimensions of the cyst were evaluated on the radiograph according to the proforma. Subsequent radiographs were taken at regular intervals of 1.5, 3, and 6 months using standard parameters and were analyzed using MCID™ analysis software of imaging research.
  
  
  RESULTS
  Mean reduction was seen in up to 39 and 60% in the cystic cavity size and increase in the mean density up to 59 and 90.2% at 3 and 6 months intervals respectively.
  
  
  CONCLUSIONS
  Spontaneous bone regeneration was seen even after primary closure of the large cystic defect without the need for placement of foreign substances or grafts and it also eliminated the complications resulting from placement of foreign substance. Further studies are required in a larger sample with longer follow-up durations to confirm the outcome of the present work for the benefit of patients.
  
  
  CONCLUSIONS
  The present study depicted that spontaneous bone regeneration can occur with accepted results after simple enucleation of jaw cyst without the aid of any graft material. Hence, simple enucleation may be considered as a first line of treatment modality for cystic lesion of the jaws. This simplifies the surgical procedure, decreases the economic and biologic costs, and reduces the risk of postoperative complications. Follow-up is necessary along with patient's compliance for the success of treatment.
authors.affiliation: Reader, Department of Oral and Maxillofacial Surgery, Navodaya Dental College & Hospital, Raichur, Karnataka, India, Phone: +918792462013, e-mail: drshivaraj4you@yahoo.com.
authors.forename: Shivaraj S
authors.initials: SS
authors.lastname: Wagdargi
authors.affiliation: Department of Oral and Maxillofacial Surgery, Bapuji Dental College & Hospital, Davangere, Karnataka, India.
authors.forename: Kirthi Kumar
authors.initials: KK
authors.lastname: Rai
authors.affiliation: Department of Oral and Maxillofacial Surgery, Subharti Dental College, Meerut, Uttar Pradesh, India.
authors.forename: K V
authors.initials: KV
authors.lastname: Arunkumar
authors.affiliation: Department of Oral and Maxillofacial Surgery, Government Dental College, Bellary, Karnataka, India.
authors.forename: Basavraj
authors.initials: B
authors.lastname: Katkol
authors.affiliation: Department of Oral and Maxillofacial Surgery, Navodaya Dental College & Hospital, Raichur, Karnataka, India.
authors.forename: Gururaj
authors.initials: G
authors.lastname: Arakeri
mesh_terms: D000293:Adolescent; D000328:Adult; D001861:Bone Regeneration / Q000502:physiology*; D005260:Female; D006801:Humans; D007570:Jaw Cysts / Q000000981:diagnostic imaging* / Q000601:surgery*; D008297:Male; D011857:Radiographic Image Interpretation, Computer-Assisted; D011862:Radiography, Panoramic; D012984:Software; D016896:Treatment Outcome
keywords: Bone regeneration; Cyst enucleation; MCID; Orthopantomogram; Radiographic evaluation.