title: High speed optical holography of retinal blood flow.
abstract: We performed noninvasive video imaging of retinal blood flow in a pigmented rat by holographic interferometry of near-infrared laser light backscattered by retinal tissue, beating against an off-axis reference beam sampled at a frame rate of 39 kHz with a high throughput camera. Local Doppler contrasts emerged from the envelopes of short-time Fourier transforms and the phase of autocorrelation functions of holograms rendered by Fresnel transformation. This approach permitted imaging of blood flow in large retinal vessels (∼30 microns diameter) over 400×400  pixels with a spatial resolution of ∼8 microns and a temporal resolution of ∼6.5  ms.
authors.forename: M
authors.initials: M
authors.lastname: Pellizzari
authors.forename: M
authors.initials: M
authors.lastname: Simonutti
authors.forename: J
authors.initials: J
authors.lastname: Degardin
authors.forename: J-A
authors.initials: JA
authors.lastname: Sahel
authors.forename: M
authors.initials: M
authors.lastname: Fink
authors.forename: M
authors.initials: M
authors.lastname: Paques
authors.forename: M
authors.initials: M
authors.lastname: Atlan