title: Modification of cerebral vascular anatomy induced by Leo stent placement depending on the site of stenting: A series of 102 cases.
abstract: OBJECTIVE
  Recent studies demonstrated the capacity of stents to modify cerebral vascular anatomy. This study evaluates arterial anatomy deformation after Leo stent placement according to the stenting site and the impact on the immediate postoperative and six-month degree of aneurysmal occlusion.
  
  
  METHODS
  A total of 102 stents were placed against the neck of aneurysms situated in the anterior cerebral circulation. Aneurysms were classified into two groups: The first was called the distal group (n = 62) and comprised aneurysms situated in the middle cerebral and anterior communicating arteries and the second was called the proximal group (n = 40) and comprised aneurysms in other sites. The stented arterial segment was classified as deformed or non-deformed by blinded review and superimposition of anonymised films before and after stenting. The degree of occlusion was determined immediately postoperatively and at six months.
  
  
  RESULTS
  Significantly, anatomical deformity was observed in the distal group compared to the proximal group (85% vs 28%). No significant difference was observed between the two groups in terms of postoperative degree of occlusion. At six months, a significant difference was observed between the two groups: three recurrences in the distal group vs 10 recurrences in the proximal group. Two (3%) recurrences were observed in the deformed group vs 11 (31%) recurrences in the non-deformed group.
  
  
  CONCLUSIONS
  Arterial deformity induced by stenting is even more marked for distal aneurysms. The recurrence rate is smaller when the stent placement results in an arterial anatomical change. The percentage of recurrence is lower when anatomy was amended by stent implantation.
authors.affiliation: University Teaching Hospital of Nice, Pasteur Hospital, Radiology Department, Neural Intervention Unit, France chau.y@chu-nice.fr.
authors.forename: Y
authors.initials: Y
authors.lastname: Chau
authors.affiliation: University Teaching Hospital of Nice, Pasteur Hospital, Radiology Department, Neural Intervention Unit, France.
authors.forename: L
authors.initials: L
authors.lastname: Mondot
authors.affiliation: University Teaching Hospital of Nice, Pasteur Hospital, Radiology Department, Neural Intervention Unit, France.
authors.forename: M
authors.initials: M
authors.lastname: Sachet
authors.affiliation: La Timone Hospital, Public Health and Medical Information Department, University Teaching Hospital of Marseilles, France.
authors.forename: J
authors.initials: J
authors.lastname: Gaudart
authors.affiliation: University Teaching Hospital of Nice, Neurosurgery Department, France.
authors.forename: D
authors.initials: D
authors.lastname: Fontaine
authors.affiliation: University Teaching Hospital of Nice, Neurosurgery Department, France.
authors.forename: M
authors.initials: M
authors.lastname: Lonjon
authors.affiliation: University Teaching Hospital of Nice, Pasteur Hospital, Radiology Department, Neural Intervention Unit, France.
authors.forename: J
authors.initials: J
authors.lastname: Sédat
mesh_terms: D000328:Adult; D000368:Aged; D017542:Aneurysm, Ruptured / Q000628:therapy; D020771:Anterior Cerebral Artery / Q000000981:diagnostic imaging; D002533:Cerebral Angiography; D002536:Cerebral Arteries / Q000000981:diagnostic imaging*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D002532:Intracranial Aneurysm / Q000000981:diagnostic imaging / Q000628:therapy; D008297:Male; D008875:Middle Aged; D020768:Middle Cerebral Artery / Q000000981:diagnostic imaging; D020769:Posterior Cerebral Artery / Q000000981:diagnostic imaging; D012008:Recurrence; D015607:Stents; D016896:Treatment Outcome; D055815:Young Adult
keywords: Aneurysm; haemodynamic; intracranial; stent