title: Membraneless Gas-Separation Microfluidic Paper-Based Analytical Devices for Direct Quantitation of Volatile and Nonvolatile Compounds.
abstract: This work presents new chemical sensing devices called "membraneless gas-separation microfluidic paper-based analytical devices" (MBL-GS μPADs). MBL-GS μPADs were designed to make fabrication of the devices simple and user-friendly. MBL-GS μPADs offer direct quantitative analysis of volatile and nonvolatile compounds. Porous hydrophobic membrane is not needed for gas-separation, which makes fabrication of the device simple, rapid and low-cost. A MBL-GS μPAD consists of three layers: "donor layer", "spacer layer", and "acceptor layer". The donor and acceptor layers are made of filter paper with a printed pattern. The donor and acceptor layers are mounted together with a spacer layer in between. This spacer is a two-sided mounting tape, 0.8 mm thick, with a small disc cut out for the gas from the donor zone to diffuse to the acceptor zone. Photographic image of the color that is formed by the reagent in the acceptor layer is analyzed using the ImageJ program for quantitation. Proof of concept of the MBL-GS μPADs was demonstrated by analyzing standard solutions of ethanol, sulfide, and ammonium. Optimization of the MBL-GS μPADs was carried out for direct determination of ammonium in wastewaters and fertilizers to demonstrate the applicability of the system to real samples.
authors.affiliation: Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs), Mahidol University Rama 6 Road, Bangkok 10400, Thailand.|Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
authors.forename: Piyawan
authors.initials: P
authors.lastname: Phansi
authors.affiliation: Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs), Mahidol University Rama 6 Road, Bangkok 10400, Thailand.|Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
authors.forename: Saichon
authors.initials: S
authors.lastname: Sumantakul
authors.affiliation: Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
authors.forename: Thinnapong
authors.initials: T
authors.lastname: Wongpakdee
authors.affiliation: Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
authors.forename: Nutnaree
authors.initials: N
authors.lastname: Fukana
authors.affiliation: Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs), Mahidol University Rama 6 Road, Bangkok 10400, Thailand.|Department of Chemistry, Faculty of Science, Srinakharinwirot University , Sukhumvit 23, Bangkok 10110, Thailand.
authors.forename: Nuanlaor
authors.initials: N
authors.lastname: Ratanawimarnwong
authors.affiliation: Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs), Mahidol University Rama 6 Road, Bangkok 10400, Thailand.|Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
authors.forename: Jirayu
authors.initials: J
authors.lastname: Sitanurak
authors.affiliation: Flow Innovation-Research for Science and Technology Laboratories (FIRST Labs), Mahidol University Rama 6 Road, Bangkok 10400, Thailand.|Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Mahidol University , Rama 6 Road, Bangkok 10400, Thailand.
authors.forename: Duangjai
authors.initials: D
authors.lastname: Nacapricha