title: Copper-Catalyzed Enantioselective Allyl-Allyl Coupling between Allylic Boronates and Phosphates with a Phenol/N-Heterocyclic Carbene Chiral Ligand.
abstract: Copper-catalyzed enantioselective allyl-allyl coupling between allylboronates and either Z-acyclic or cyclic allylic phosphates using a new chiral N-heterocyclic carbene ligand, bearing a phenolic hydroxy, is reported. This reaction occurs with exceptional SN 2'-type regioselectivities and high enantioselectivities to deliver chiral 1,5-diene derivatives with a tertiary stereogenic center at the allylic/homoallylic position.
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, 060-0810, Japan.
authors.forename: Yuto
authors.initials: Y
authors.lastname: Yasuda
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, 060-0810, Japan. ohmiya@sci.hokudai.ac.jp.
authors.forename: Hirohisa
authors.initials: H
authors.lastname: Ohmiya
authors.affiliation: Department of Chemistry, Faculty of Science, Hokkaido University, Sapporo, 060-0810, Japan. sawamura@sci.hokudai.ac.jp.
authors.forename: Masaya
authors.initials: M
authors.lastname: Sawamura
keywords: allylic compounds; asymmetric catalysis; boron; copper; synthetic methods