title: Response to comment on "Cancer chemoprevention: Evidence of a nonlinear dose response for the protective effects of resveratrol in humans and mice".
abstract: Low-dose resveratrol did not have the opposite effect on intestinal adenoma development when given in a standard diet instead of a high-fat diet, although we agree on the need for more information on the interaction of diet-derived compounds such as resveratrol and other lifestyle, metabolic and hormonal factors.
authors.affiliation: Cancer Chemoprevention Group, Department of Cancer Studies, Cancer Research UK Leicester Centre, University of Leicester, Leicester LE2 7LX, UK.
authors.forename: Karen
authors.initials: K
authors.lastname: Brown
authors.affiliation: Cancer Chemoprevention Group, Department of Cancer Studies, Cancer Research UK Leicester Centre, University of Leicester, Leicester LE2 7LX, UK.
authors.forename: Alessandro
authors.initials: A
authors.lastname: Rufini
authors.affiliation: Cancer Chemoprevention Group, Department of Cancer Studies, Cancer Research UK Leicester Centre, University of Leicester, Leicester LE2 7LX, UK.
authors.forename: Andreas
authors.initials: A
authors.lastname: Gescher
mesh_terms: D000236:Adenoma / Q000188:drug therapy; D000818:Animals; D000975:Antioxidants / Q000008:administration & dosage / Q000627:therapeutic use; D063646:Carcinogenesis / Q000187:drug effects; D018890:Chemoprevention / Q000379:methods*; D015179:Colorectal Neoplasms / Q000188:drug therapy; D059305:Diet, High-Fat / Q000009:adverse effects; D005260:Female; D006801:Humans; D008297:Male; D051379:Mice; D000077185:Resveratrol; D013267:Stilbenes / Q000008:administration & dosage / Q000627:therapeutic use*
chemical_list: D000975:Antioxidants; D013267:Stilbenes; D000077185:Resveratrol