title: Management of Supplemental Oxygen for Infants with Persistent Pulmonary Hypertension of Newborn: A Survey.
abstract: ObjectiveTo evaluate practice variations amongst neonatologists regarding oxygen management in neonates with persistent pulmonary hypertension of newborn (PPHN).Study DesignAn online survey was administered to neonatologists to assess goal oxygenation targets and oxygen titration practices in PPHN. Response variations were assessed and intergroup comparisons performed.ResultsThirty-three percent (492) of neonatologists completed the survey. Twenty-eight percent reported using specific oxygen titration guidelines. Majority of respondents used a combination of oxygen saturation (SpO2) and arterial oxygen tension (PaO2) initially to titrate oxygen. Seventy percent of the respondents used higher goal SpO2> 95% or 95 to 98% and thirty-eight percent of the respondents used PaO2> 80 mm Hg. Physicians with extracorporeal membrane oxygenation experience and those with greater than ten years neonatal intensive care unit experience inclined toward use of SpO2alone for oxygen titration and aimed for lower range of SpO2and PaO2targets. Greater proportion of neonatologists who employed specific oxygen titration guidelines used lower SpO2targets.ConclusionWide practice variations exist amongst neonatologists regarding optimal SpO2and PaO2targets and oxygen titration practices in the management of PPHN.
authors.affiliation: Department of Pediatrics, Nemours, Alfred I. duPont Hospital for Children, Wilmington, Delaware.
authors.forename: Deepthi
authors.initials: D
authors.lastname: Alapati
authors.affiliation: Department of Pediatrics, Nemours, Alfred I. duPont Hospital for Children, Wilmington, Delaware.
authors.forename: Romal
authors.initials: R
authors.lastname: Jassar
authors.affiliation: Department of Pediatrics, Nemours, Alfred I. duPont Hospital for Children, Wilmington, Delaware.
authors.forename: Thomas H
authors.initials: TH
authors.lastname: Shaffer
mesh_terms: D002983:Clinical Competence; D002985:Clinical Protocols; D003430:Cross-Sectional Studies; D006801:Humans; D007231:Infant, Newborn; D015931:Intensive Care, Neonatal; D009359:Neonatology / Q000379:methods*; D010100:Oxygen / Q000008:administration & dosage* / Q000097:blood*; D010102:Oxygen Inhalation Therapy; D010313:Partial Pressure; D010547:Persistent Fetal Circulation Syndrome / Q000628:therapy*; D017410:Practice Guidelines as Topic; D010818:Practice Patterns, Physicians'; D011446:Prospective Studies; D011795:Surveys and Questionnaires
chemical_list: D010100:Oxygen