title: [Sinonasal fungal infections are not exclusively due to mucorales and Aspergillus!].
abstract: Rhino-sinusal infections are serious diseases and possibly lethal. When they are invasive, we easily discuss apergilloses and mucormycoses. The confirmation of the diagnosis of mucormycosis need an extensive surgery for precise histopathological and mycological evaluation. The pathologist may be faced to other rare mycoses such as phaeohyphomycoses, which present different morphological features than mucormycoses and Aspergillus. Once the diagnosis is established, an appropriate antifungal treatment is quickly started. The aim of our work is to report two observations of phaeohyphomycoses, to describe their histopathological features, to discuss complementary diagnostic methods and to present the main differential diagnoses.
authors.affiliation: Service d'anatomie et cytologie pathologiques, faculté de médecine, université Paris Diderot - Paris 7, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France. Electronic address: arnault.tauziedeespariat@gmail.com.
authors.forename: Arnault
authors.initials: A
authors.lastname: Tauziède-Espariat
authors.affiliation: Service d'anatomie et cytologie pathologiques, faculté de médecine, université Paris Diderot - Paris 7, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France.
authors.forename: Michel
authors.initials: M
authors.lastname: Wassef
authors.affiliation: Service d'anatomie et cytologie pathologiques, faculté de médecine, université Paris Diderot - Paris 7, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France.
authors.forename: Homa
authors.initials: H
authors.lastname: Adle-Biassette
authors.affiliation: Service de parasitologie-mycologie, hôpital Saint-Louis, AP-HP, 75010 Paris, France; Unité de mycologie moléculaire, CNRS URA3012, centre national de référence mycoses invasives et antifongiques, Institut Pasteur, 28, rue du Dr.-Roux, 75724 Paris, France.
authors.forename: Alexandre
authors.initials: A
authors.lastname: Alanio
authors.affiliation: Service de parasitologie-mycologie, hôpital Saint-Louis, AP-HP, 75010 Paris, France; Unité de mycologie moléculaire, CNRS URA3012, centre national de référence mycoses invasives et antifongiques, Institut Pasteur, 28, rue du Dr.-Roux, 75724 Paris, France.
authors.forename: Stéphane
authors.initials: S
authors.lastname: Bretagne
authors.affiliation: Service de maladies infectieuses, hôpital Necker, 75015 Paris, France.
authors.forename: Fanny
authors.initials: F
authors.lastname: Lanternier
authors.affiliation: Service de dermatologie, hôpital Mohamed V, 10000 Rabat, Maroc.
authors.forename: Mohammed
authors.initials: M
authors.lastname: Boui
authors.affiliation: Services de maladies infectieuses, hôpital Avicenne, 93009 Bobigny, France.
authors.forename: Olivier
authors.initials: O
authors.lastname: Bouchaud
authors.affiliation: Service d'otorhinolaryngologie, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France.
authors.forename: Pierre
authors.initials: P
authors.lastname: Vironneau
authors.affiliation: Service d'otorhinolaryngologie, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France.
authors.forename: Romain
authors.initials: R
authors.lastname: Kania
authors.affiliation: Unité d'histopathologie humaine et modèles animaux, Institut Pasteur, 28, rue du Dr.-Roux, 75724 Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, Paris, France.
authors.forename: Grégory
authors.initials: G
authors.lastname: Jouvion
authors.affiliation: Unité d'histopathologie humaine et modèles animaux, Institut Pasteur, 28, rue du Dr.-Roux, 75724 Paris, France; Université Paris Descartes, PRES Sorbonne Paris Cité, Paris, France; Service de neuropathologie, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75475 Paris, France.
authors.forename: Fabrice
authors.initials: F
authors.lastname: Chrétien
authors.affiliation: Service d'anatomie et cytologie pathologiques, faculté de médecine, université Paris Diderot - Paris 7, AP-HP Lariboisière, 2, avenue Ambroise-Paré, 75475 Paris, France.
authors.forename: Marion
authors.initials: M
authors.lastname: Classe
mesh_terms: D000328:Adult; D000528:Alternaria / Q000302:isolation & purification* / Q000648:ultrastructure; D060487:Alternariosis / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D000666:Amphotericin B / Q000008:administration & dosage / Q000627:therapeutic use; D000935:Antifungal Agents / Q000627:therapeutic use; D003131:Combined Modality Therapy; D003646:Debridement; D003937:Diagnosis, Differential; D042241:Early Diagnosis; D017809:Fatal Outcome; D005260:Female; D006801:Humans; D008081:Liposomes; D008417:Mastoiditis / Q000188:drug therapy / Q000382:microbiology / Q000601:surgery; D060446:Phaeohyphomycosis / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D011183:Postoperative Complications / Q000209:etiology; D012189:Retrospective Studies; D012220:Rhinitis / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy; D012772:Shock, Septic / Q000209:etiology; D012852:Sinusitis / Q000175:diagnosis / Q000382:microbiology* / Q000473:pathology / Q000628:therapy
chemical_list: D000935:Antifungal Agents; D008081:Liposomes; C068538:liposomal amphotericin B; D000666:Amphotericin B
keywords: Alternaria; Aspergillose; Aspergillosis; Invasive; Mucormycose; Mucormycosis