title: Near Full-Length Genomic Sequences of Two Novel HIV-1 Recombinant Forms Identified in Shenzhen, China.
abstract: Most HIV subtypes prevalent in China can be found in Shenzhen, including CRF07_BC, CRF01_AE, CRF08_BC, CRF55_01B, and subtype B. Multiple subtypes spreading in the same population always lead to the emergence of unique recombinant strains. Here, we report two unique recombinant forms (SZ44LS7251 and SZ95LS8027) of HIV-1 identified in a heterosexual population. Recombinant analyses were fulfilled based on the near full-length genomes. Both strains comprise subtypes B, C, and CRF01_AE. Phylogenetic analysis reveals that SZ44LS7251 is the second generation recombination originated from CRF55_01B andCRF07_BC, whereas SZ95LS8027 comprises CRF01_AE and CRF07_BC.The emergence of second generation recombination of HIV with complicated genomic structures supposed that high ratio of super infections or coinfections might happen in the Shenzhen area.
authors.affiliation: 1 Graduate School, Anhui Medical University , Anhui, China .
authors.forename: Dijing
authors.initials: D
authors.lastname: Jia
authors.affiliation: 2 Shenzhen Center for Disease Control and Prevention , Shenzhen, China .
authors.forename: Jin
authors.initials: J
authors.lastname: Zhao
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Tianyi
authors.initials: T
authors.lastname: Li
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Changrong
authors.initials: C
authors.lastname: Sun
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Hanping
authors.initials: H
authors.lastname: Li
authors.affiliation: 2 Shenzhen Center for Disease Control and Prevention , Shenzhen, China .
authors.forename: Chenli
authors.initials: C
authors.lastname: Zheng
authors.affiliation: 2 Shenzhen Center for Disease Control and Prevention , Shenzhen, China .
authors.forename: Lin
authors.initials: L
authors.lastname: Chen
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Yongjian
authors.initials: Y
authors.lastname: Liu
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Siyang
authors.initials: S
authors.lastname: Liu
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Daomin
authors.initials: D
authors.lastname: Zhuang
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Xiaolin
authors.initials: X
authors.lastname: Wang
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Zuoyi
authors.initials: Z
authors.lastname: Bao
authors.affiliation: 3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Jingyun
authors.initials: J
authors.lastname: Li
authors.affiliation: 1 Graduate School, Anhui Medical University , Anhui, China .|3 Department of AIDS Research, State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology , Beijing, China .
authors.forename: Lin
authors.initials: L
authors.lastname: Li
mesh_terms: D000328:Adult; D002681:China; D016000:Cluster Analysis; D019143:Evolution, Molecular; D005260:Female; D016679:Genome, Viral; D005838:Genotype; D015658:HIV Infections / Q000821:virology*; D015497:HIV-1 / Q000145:classification* / Q000235:genetics* / Q000302:isolation & purification; D020010:Heterosexuality; D006801:Humans; D008297:Male; D008875:Middle Aged; D010802:Phylogeny; D011995:Recombination, Genetic; D017422:Sequence Analysis, DNA
keywords: China; HIV; HIV genetics; URF