title: A case of desmoid tumor co-existing with recurrent squamous cell carcinoma in the larynx.
abstract: Extra-abdominal desmoid tumor, also known as aggressive fibromatosis, has aggressive behavior with local infiltration and tendency for recurrence. Though head and neck is reported to be one of the most common sites, a desmoid tumor in the larynx is extremely rare. A 67-year-old male visited our hospital with prolonged hoarseness and received laryngo-microsurgery with the diagnosis of laryngeal polyp. After the operation, he eventually developed a laryngeal squamous cell carcinoma with papilloma, confirmed by second laryngo-microsurgery and received radiation therapy. After the third laryngo-microsurgery to remove residual papilloma, white irregular mass appeared on the right vocal cord and grew rapidly beneath the glottis, causing dyspnea. After 2 additional laryngo-microsurgeries, he was diagnosed having the dermoid tumor co-existing with recurrent squamous cell carcinoma. He underwent near-total laryngectomy and is currently alive without disease, speaking using a vocal shunt. Only five cases of the desmoid tumors arising in the adult larynx have been reported in the English literature. In this case, repeated surgery and radiation were suspected as the causes. Also, the present report is the first to describe desmoid tumor co-existing with recurrent squamous cell carcinoma in the larynx.
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Kobe City Medical Center General Hospital, Minatojima-minamimachi 2-1-1, Chuo-ku, Kobe 650-0047, Japan. Electronic address: sinosino@kcho.jp.
authors.forename: Shogo
authors.initials: S
authors.lastname: Shinohara
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Sakyo-Ku, Kyoto 606-8507, Japan.
authors.forename: Atsushi
authors.initials: A
authors.lastname: Suehiro
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Kobe City Medical Center General Hospital, Minatojima-minamimachi 2-1-1, Chuo-ku, Kobe 650-0047, Japan.
authors.forename: Masahiro
authors.initials: M
authors.lastname: Kikuchi
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Kobe City Medical Center General Hospital, Minatojima-minamimachi 2-1-1, Chuo-ku, Kobe 650-0047, Japan.
authors.forename: Hiroyuki
authors.initials: H
authors.lastname: Harada
authors.affiliation: Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Sakyo-Ku, Kyoto 606-8507, Japan.
authors.forename: Ippei
authors.initials: I
authors.lastname: Kishimoto
authors.affiliation: Department of Pathology, Kobe City Medical Center General Hospital, Minatojima-minamimachi 2-1-1, Chuo-ku, Kobe 650-0047, Japan.
authors.forename: Yukihiro
authors.initials: Y
authors.lastname: Imai
mesh_terms: D000368:Aged; D002294:Carcinoma, Squamous Cell / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D018222:Desmoid Tumors / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006258:Head and Neck Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D006801:Humans; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D007825:Laryngectomy; D008279:Magnetic Resonance Imaging; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D016609:Neoplasms, Second Primary / Q000000981:diagnostic imaging / Q000473:pathology / Q000601:surgery*; D000077195:Squamous Cell Carcinoma of Head and Neck
keywords: Aggressive fibromatosis; Desmoid tumor; Larynx; Near-total laryngectomy; Squamous cell carcinoma