title: The Association between Vitamin D and Health-Related Quality of Life in Korean Adults.
abstract: BACKGROUND
  We examined the relationship between vitamin D status and health-related quality of life, and explored other related factors in the general Korean population.
  
  
  METHODS
  We used data from the 2007-2012 Korea National Health and Nutrition Examination Survey on 14,104 adults, aged 20-49 years, who had consented to serum vitamin D measurement and answered health-related quality of life questions. EuroQol-5 was used for measurement. Serum vitamin D levels were measured at intervals of 0-9.99, 10-19.99, 20-29.99, and ≥30 ng/mL.
  
  
  RESULTS
  Participants with higher serum vitamin D (serum 25-hydroxyvitamin D) levels were significantly less likely to report problems with depression and anxiety. After adjustment for age, gender, income level, education level, marital status, alcohol consumption, smoking status, and the existence of depressive disorders, the odds ratio for reporting a problem with depression and anxiety was 0.60 (95% confidence interval [CI], 0.39-0.91). The odds ratio for the prevalence of any problem was 0.69 (95% CI, 0.53-0.89) before adjustment, but was not statistically significant after adjustment. No significant associations were observed for problems with mobility, self-care, usual activity, or pain and discomfort.
  
  
  CONCLUSIONS
  This is the first study to examine the associations between vitamin D and health-related quality of life for the general Korean population. Vitamin D status was not significantly associated with the dimensions of EuroQol-5 except for depression and anxiety problems.
authors.affiliation: Department of Family Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Ji Sun
authors.initials: JS
authors.lastname: Kim
authors.affiliation: Department of Family Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
authors.forename: Young Eun
authors.initials: YE
authors.lastname: Choi
authors.affiliation: Department of Biostatistics, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Jin Kyung
authors.initials: JK
authors.lastname: Baek
authors.affiliation: Department of Biostatistics, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Ho Jin
authors.initials: HJ
authors.lastname: Cho
authors.affiliation: Department of Family Medicine, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
authors.forename: Ye Seul
authors.initials: YS
authors.lastname: Kim
keywords: Anxiety; Depression; Quality of Life; Vitamin D