title: High-temporal-resolution, full-field optical angiography based on short-time modulation depth for vascular occlusion tests.
abstract: We developed high-temporal-resolution, full-field optical angiography for use in vascular occlusion tests (VOTs). In the proposed method, undersampled signals are acquired by a high-speed digital camera that separates the dynamic and static speckle signals. The two types of speckle signal are used to calculate the short-time modulation depth (STMD) of each of the camera pixels. STMD is then used to realize high-temporal-resolution, full-field optical angiography. Phantom and biological experiments conducted and demonstrated the feasibility of using our proposed method to perform VOTs and to study the reaction kinetics in microfluidic systems.
authors.affiliation: Foshan University, Department of Photoelectric Technology, Foshan 528000, ChinabSouth China Normal University, School of Physics and Telecommunication, Guangzhou 510006, China.
authors.forename: Riwei
authors.initials: R
authors.lastname: Liao
authors.affiliation: Foshan University, Department of Photoelectric Technology, Foshan 528000, China.
authors.forename: Mingyi
authors.initials: M
authors.lastname: Wang
authors.affiliation: Foshan University, Department of Photoelectric Technology, Foshan 528000, China.
authors.forename: Dingan
authors.initials: D
authors.lastname: Han
authors.affiliation: South China Normal University, School of Physics and Telecommunication, Guangzhou 510006, China.
authors.forename: Zuohua
authors.initials: Z
authors.lastname: Huang
authors.affiliation: Foshan University, Department of Photoelectric Technology, Foshan 528000, China.
authors.forename: Yaguang
authors.initials: Y
authors.lastname: Zeng
mesh_terms: D000792:Angiography / Q000295:instrumentation / Q000379:methods*; D006801:Humans; D044085:Microfluidics; D019047:Phantoms, Imaging; D014652:Vascular Diseases / Q000000981:diagnostic imaging*