title: Bioimpacts of dialyzer variety on phosphorus level in Iranian hemodialysis patients.
abstract: BACKGROUND
  Cardiovascular events are the major cause of death in patients with chronic renal failure. About half of dialysis patients because of reduced phosphorus clearance have hyperphosphatemia. Hyperphosphatemia and following secondary hyperparathyroidism lead to some cardiovascular changes. Hemodialysis (HD) partly removes phosphorus during each dialysis session.
  
  
  OBJECTIVE
  Presented study was designed to evaluate dialyzer variation effect on phosphorus level as a prognostic factor after dialysis using.
  
  
  METHODS
  Six kinds of dialyzer were used for dialysis; low flux (LF) dialyzer (F7 and F8), high flux (HF) dialyzer (F70 and F80) and finally hollow-fiber dialyzers including polyethersulfone (PES) 130 HF and polysulfone (PS) 13 LF. Fifty-seven patients were divided into 6 matched groups included three groups of 10 people and 3 groups of 9 persons in groups: A (F70), B (F80), C (F7), D (F8), E (PES 130 HF) and F (PS 13 LF). Patients were treated for one month with these dialyzers. At the end of the month, blood samples were taken again for phosphorus level before dialysis handling.
  
  
  RESULTS
  The mean pre-dialysis serum phosphorus was 5.03, 5.4, 5.2, 4.6, 4.95 and 5.1 mg/dl and the mean phosphorus was 5.43, 5.01, 4.9, 4.18, 4.17 and 5.3 mg/dl after one month of dialysis, respectively in groups A to F without any statistically differences between pre- and after one month dialysis values respectively.
  
  
  CONCLUSIONS
  The findings indicate dialyzer type in the control of serum phosphorus has not been effective in the short-term HD. We suggest a study with more duration time.
authors.affiliation: Zanjan Metabolic Disease Research Center, Zanjan University of Medical Sciences, Zanjan, Iran ; Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Aiyoub
authors.initials: A
authors.lastname: Pezeshgi
authors.affiliation: Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Bahareh
authors.initials: B
authors.lastname: Moharrami
authors.affiliation: Department of Epidemiology, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Goodarz
authors.initials: G
authors.lastname: Kolifarhood
authors.affiliation: Department of Internal Medicine, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Alireza
authors.initials: A
authors.lastname: Sadeghi
authors.affiliation: Zanjan Applied Pharmacology Research Center, Zanjan University of Medical Sciences, Zanjan, Iran ; Department of Pharmacotherapy, School of Pharmacy, Zanjan University of Medical Sciences, Zanjan, Iran.
authors.forename: Masoud
authors.initials: M
authors.lastname: Asadi-Khiavi
keywords: Dialyzer; Hemodialysis; Phosphorus