title: Effects of High-Intensity-Focused Ultrasound Treatment on Benign Uterine Tumor.
abstract: In this study, the effects of high-intensity-focused ultrasound (HIFU) treatment on benign uterine tumor patients were examined. A total of 333 patients diagnosed with fibroids or adenomyosis using diagnostic sonography, treated with HIFU between February 4, 2010 and December 29, 2014 at a hospital in Korea, and followed up for three or six months were selected for this study. Their benign uterine tumor volume was measured, and the effects of HIFU treatment on the volume were analyzed according to age, disease, fertility, and treatment duration. The volume of benign tumors of the uterus changed by age in all age groups after conducting HIFU treatment for 3 and 6 months, respectively. The rate of decrease in individuals' in their twenties was the largest, at 64.9%. When the decreasing volume of benign tumors of the uterus was analyzed by type of disease, the treatment efficacy for adenomyosis was the best, with a decrease of 164.83 cm(3) after 6 months. Myoma had the fastest decreasing rate, at 68.5%. When evaluated on the basis of fertility, the volume of benign tumors of the uterus continued to decrease until 6 months after completing all procedures. The volume has continued to decrease for 6 months after all procedures. This study showed that HIFU treatments for uterine fibroid and adenomyosis is an effective non-invasive therapy via reducing the benign uterine tumor volume. Therefore, the HIFU method might replace other conventional treatment methods.
authors.affiliation: Department of Radiology, Incheon Christian Hospital, Incheon, Korea.; Department of Radiological Science, Gachon University Medical Campus, Incheon, Korea.
authors.forename: Jaeyoon
authors.identifier: 0000-0001-7212-7391
authors.initials: J
authors.lastname: Park
authors.affiliation: Department of Obstetrics and Gynaecology, Aegis Womanmed Clinic, Seoul, Korea .
authors.forename: Jae Seong
authors.identifier: 0000-0002-3988-1496
authors.initials: JS
authors.lastname: Lee
authors.affiliation: Department of Radiological Technology, Ansan College, Ansan, Korea .
authors.forename: Jae-Hwan
authors.identifier: 0000-0001-7112-3866
authors.initials: JH
authors.lastname: Cho
authors.affiliation: Department of Radiological Science, Gachon University Medical Campus, Incheon, Korea .
authors.forename: Sungchul
authors.identifier: 0000-0002-4195-1297
authors.initials: S
authors.lastname: Kim
mesh_terms: D062788:Adenomyosis / Q000000981:diagnostic imaging; D000328:Adult; D005260:Female; D006801:Humans; D007889:Leiomyoma / Q000000981:diagnostic imaging; D008875:Middle Aged; D016896:Treatment Outcome; D014464:Ultrasonic Therapy; D014594:Uterine Neoplasms / Q000503:physiopathology / Q000532:radiotherapy*; D014599:Uterus / Q000503:physiopathology
keywords: Benign Uterine Tumor; High-Intensity-Focused Ultrasound; Treatment Effects