title: Heritability of Batrachochytrium dendrobatidis burden and its genetic correlation with development time in a population of Common toad (Bufo spinosus).
abstract: Despite the important threat that emerging pathogens pose for the conservation of biodiversity as well as human health, very little is known about the adaptive potential of host species to withstand infections. We studied the quantitative genetic architecture responsible for the burden of the fungal pathogen Batrachochytrium dendrobatidis in a population of common toads in conjunction with other life-history traits (i.e., body size and development rate) that may be affected by common selective pressures. We found a significant heritable component that is associated with fungal burden, which may allow for local adaptation to this pathogen to proceed. In addition, the high genetic correlation found between fungal burden and development time suggests that both traits have to be taken into account in order to assess the adaptive response of host populations to this emerging pathogen.
authors.affiliation: Research Unit of Biodiversity (UO-CSIC-PA), Edificio de Investigación, Gonzalo Gutiérrez Quirós s/n, 33600, Mieres, Spain. gemma.palomar@yahoo.es.|Department of Biology of Organisms and Systems, University of Oviedo, Catedrático Rodrigo Uría s/n, 33006, Oviedo, Spain. gemma.palomar@yahoo.es.
authors.forename: Gemma
authors.initials: G
authors.lastname: Palomar
authors.affiliation: Museo Nacional de Ciencias Naturales, CSIC, José Gutiérrez Abascal, 2, 28006, Madrid, Spain.|Centro de Investigación, Seguimiento y Evaluación, Parque Nacional de la Sierra de Guadarrama, Cta. M-604, Km. 27.6, 28740, Rascafría, Spain.
authors.forename: Jaime
authors.initials: J
authors.lastname: Bosch
authors.affiliation: Research Unit of Biodiversity (UO-CSIC-PA), Edificio de Investigación, Gonzalo Gutiérrez Quirós s/n, 33600, Mieres, Spain.|Department of Biology of Organisms and Systems, University of Oviedo, Catedrático Rodrigo Uría s/n, 33006, Oviedo, Spain.
authors.forename: José Manuel
authors.initials: JM
authors.lastname: Cano
mesh_terms: D000222:Adaptation, Physiological; D000818:Animals; D002025:Bufonidae / Q000235:genetics* / Q000254:growth & development / Q000382:microbiology; D008411:Chytridiomycota / Q000472:pathogenicity*; D000071421:Life History Traits; D012641:Selection, Genetic
keywords: Batrachochytrium dendrobatidis; chytridiomycosis; fungal burden; genetic correlation; local adaptation; quantitative genetics