title: Human Papillomavirus Types Involved in External Genital Warts in a Group of Argentinian Women in Buenos Aires.
abstract: OBJECTIVE
  The aim of the study was to understand which human papillomavirus (HPV) types are involved in external genital warts (GWs) in a group of Argentinian women in Buenos Aires.
  
  
  METHODS
  One hundred sixty consecutive women 15 to 45 years old with GWs were enrolled. All patients underwent confirmatory biopsy. In 150 of 160 patients, the diagnosis of GWs was confirmed by histology, DNA-HPV was investigated using polymerase chain reaction, and sequence analysis with generic primers MY09/11 was performed.
  
  
  RESULTS
  HPV 6 and/or 11 was detected in 93.3% patients (140/150). HPV 6 was by far the most common type (80%), followed by HPV 11 (12.7%). Coinfection with these 2 types occurred in 0.7%. HPV 16 was found in 2% and HPV 73 in 0.7%.
  
  
  CONCLUSIONS
  HPV 6 and/or 11 are present in 93.3% (95% confidence interval, 0.9-1.0) of external genital warts in a group of Argentinian women in Buenos Aires and, therefore, could be prevented with HPV vaccine (NCT 015998779).
authors.affiliation: 1Unidad del Tracto Genital Inferior Hospital de Clinicas "José de San Martín," University of Buenos Aires, Argentina; 2Department of Pathology, Hospital de Clinicas "José de San Martín," University of Buenos Aires, Argentina; and 3Area de Medicina Genomica, Genesis-MANLAB. Buenos Aires, Argentina.
authors.forename: Laura Alicia
authors.initials: LA
authors.lastname: Fleider
authors.forename: Silvio Alejandro
authors.initials: SA
authors.lastname: Tatti
authors.forename: Andrea Verónica
authors.initials: AV
authors.lastname: Suzuki
authors.forename: Verónica Andrea
authors.initials: VA
authors.lastname: Maldonado
authors.forename: Lilí Beatriz
authors.initials: LB
authors.lastname: Díaz
authors.forename: Ignacio Javier
authors.initials: IJ
authors.lastname: Chiesa
authors.forename: María Silvia
authors.initials: MS
authors.lastname: Perez
mesh_terms: D000293:Adolescent; D000328:Adult; D001118:Argentina / Q000453:epidemiology; D001706:Biopsy; D003218:Condylomata Acuminata / Q000453:epidemiology* / Q000821:virology*; D004279:DNA, Viral / Q000235:genetics / Q000302:isolation & purification; D005260:Female; D005838:Genotype; D006651:Histocytochemistry; D006801:Humans; D008875:Middle Aged; D027383:Papillomaviridae / Q000145:classification* / Q000235:genetics / Q000302:isolation & purification*; D016133:Polymerase Chain Reaction; D015995:Prevalence; D017422:Sequence Analysis, DNA; D055815:Young Adult
chemical_list: D004279:DNA, Viral