title: Targeting the fungal calcium-calcineurin signaling network in overcoming drug resistance.
authors.affiliation: School of Pharmaceutical Sciences, Shandong University, Wenhuaxi Road, Jinan, 250012, China.
authors.forename: Xiuyun
authors.initials: X
authors.lastname: Li
authors.affiliation: Department of Pharmacy, Qianfoshan Hospital Affiliated to Shandong University, Jingshi Road, Jinan, 250014, China.
authors.forename: Shujuan
authors.initials: S
authors.lastname: Sun
mesh_terms: D000935:Antifungal Agents / Q000494:pharmacology* / Q000627:therapeutic use; D019703:Calcineurin / Q000378:metabolism*; D015220:Calcium Channels / Q000378:metabolism*; D002176:Candida albicans / Q000187:drug effects / Q000378:metabolism; D002177:Candidiasis / Q000175:diagnosis / Q000188:drug therapy / Q000382:microbiology; D003524:Cyclosporins / Q000737:chemistry / Q000494:pharmacology / Q000627:therapeutic use; D025141:Drug Resistance, Fungal / Q000187:drug effects*; D005656:Fungal Proteins / Q000378:metabolism*; D018841:HSP90 Heat-Shock Proteins / Q000378:metabolism; D006801:Humans; D015398:Signal Transduction / Q000187:drug effects*; D016559:Tacrolimus / Q000494:pharmacology / Q000627:therapeutic use
chemical_list: D000935:Antifungal Agents; D015220:Calcium Channels; D003524:Cyclosporins; D005656:Fungal Proteins; D018841:HSP90 Heat-Shock Proteins; D019703:Calcineurin; D016559:Tacrolimus
keywords: Crz1; Hph1/Hph2; Hsp90; Rta2; antifungal drug development; calcineurin; calcium channels; fungal resistance; potential drug targets