title: Complete genome sequence of Lactobacillus plantarum LZ227, a potential probiotic strain producing B-group vitamins.
abstract: B-group vitamins play an important role in human metabolism, whose deficiencies are associated with a variety of disorders and diseases. Certain microorganisms such as Lactic acid bacteria (LAB) have been shown to have capacities for B-group vitamin production and thus could potentially replace chemically synthesized vitamins for food fortification. A potential probiotic strain named Lactobacillus plantarum LZ227, which was isolated from raw cow milk in this study, exhibits the ability to produce B-group vitamins. Complete genome sequencing of LZ227 was performed to gain insights into the genetic elements involved in B-group vitamin production. The genome of LZ227 contains a circular 3,131,750-bp chromosome, three circular plasmids and two predicted linear plasmids. LZ227 also contains gene clusters for biosynthesis of both riboflavin and folate. This genome sequence provides a basis for further elucidation of its molecular genetics and probiotic functions, and will facilitate its applications as starter cultures in food industry.
authors.affiliation: Key Laboratory for Food Microbial Technology of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
authors.forename: Ping
authors.initials: P
authors.lastname: Li
authors.affiliation: Key Laboratory for Food Microbial Technology of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China.
authors.forename: Qingqing
authors.initials: Q
authors.lastname: Zhou
authors.affiliation: Key Laboratory for Food Microbial Technology of Zhejiang Province, College of Food Science and Biotechnology, Zhejiang Gongshang University, Hangzhou 310018, China. Electronic address: guqing2002@hotmail.com.
authors.forename: Qing
authors.initials: Q
authors.lastname: Gu
mesh_terms: D000818:Animals; D002417:Cattle; D002874:Chromosome Mapping; D005492:Folic Acid / Q000096:biosynthesis*; D016680:Genome, Bacterial; D048191:Lactiplantibacillus plantarum / Q000145:classification / Q000235:genetics* / Q000378:metabolism; D010802:Phylogeny; D019936:Probiotics; D012256:Riboflavin / Q000096:biosynthesis*; D014803:Vitamin B Complex / Q000096:biosynthesis*
chemical_list: D014803:Vitamin B Complex; D005492:Folic Acid; D012256:Riboflavin
keywords: B-group vitamins; Complete genome sequence; Folate; L. plantarum LZ227; Riboflavin