title: IABP: history-evolution-pathophysiology-indications: what we need to know.
abstract: Treatment with the intraaortic balloon pump (IABP) is the most common form of mechanical support for the failing heart. Augmentation of diastolic pressure during balloon inflation contributes to the coronary circulation and the presystolic deflation of the balloon reduces the resistance to systolic output. Consequently, the myocardial work is reduced. The overall effect of the IABP therapy is an increase in the myocardial oxygen supply/demand ratio and thus in endocardial viability.This is an overall synopsis of what we need to know regarding IABP. Furthermore, this review article attempts to systematically delineate the pathophysiology linked with the hemodynamic consequences of IABP therapy. The authors also look at the future of the use of the balloon pump and conclude that the positive multi-systemic hemodynamic regulation during IABP treatment should further justify its use.
authors.affiliation: Cardiothoracics Department, Royal Victoria Hospital, Belfast, Northern Ireland.
authors.forename: H
authors.initials: H
authors.lastname: Parissis
authors.affiliation: Cardiothoracics Department, Royal Victoria Hospital, Belfast, Northern Ireland. vgraham87@gmail.com.
authors.forename: V
authors.initials: V
authors.lastname: Graham
authors.affiliation: Cardiothoracics Department, Royal Victoria Hospital, Belfast, Northern Ireland.
authors.forename: S
authors.initials: S
authors.lastname: Lampridis
authors.affiliation: Cardiothoracics Department, Royal Victoria Hospital, Belfast, Northern Ireland.
authors.forename: M
authors.initials: M
authors.lastname: Lau
authors.affiliation: Cardiothoracics Department, Royal Victoria Hospital, Belfast, Northern Ireland.
authors.forename: G
authors.initials: G
authors.lastname: Hooks
authors.affiliation: Cardiothoracics Department, Royal Victoria Hospital, Belfast, Northern Ireland.
authors.forename: P C
authors.initials: PC
authors.lastname: Mhandu
mesh_terms: D001794:Blood Pressure / Q000502:physiology; D003326:Coronary Circulation / Q000502:physiology; D006333:Heart Failure / Q000503:physiopathology / Q000601:surgery*; D006439:Hemodynamics; D049673:History, 20th Century; D049674:History, 21st Century; D006801:Humans; D007423:Intra-Aortic Balloon Pumping / Q000266:history; D013599:Systole / Q000502:physiology
keywords: Internal counterpulsation; Intra-aortic balloon pump; Mechanical circulatory support