title: Validation of clinical risk scores for laparoscopic liver resections of colorectal liver metastases: A 10-year observed follow-up study.
abstract: OBJECTIVE
  The aim of this study was to validate clinical risk scores in patients underwent laparoscopic resection of colorectal liver metastases (CLM) with 5 years follow-up or more, and assess 5- and 10-year actual survival in this group.
  
  
  METHODS
  A total of 516 laparoscopic liver resections were performed in 406 patients with CLM between February 1998 and September 2015. A follow-up of 5 and 10 years could be assessed in 144 and 29 patients, respectively. The Fong score, pre- and postoperative Basingstoke Predictive Index (BPI), Nordlinger score, and Iwatsuki score were validated.
  
  
  RESULTS
  Five- and ten-year cancer-related actual survival was 54% and 32%, respectively. The Fong score, pre- and postoperative BPI and the Nordlinger score divided patients into risk groups with significant difference in survival between the groups. However, predicted 5-year survival rates were lower than the actual 5-year survival (mean difference in 17%,13%, 20%, and 30%, respectively).
  
  
  CONCLUSIONS
  The Fong score, pre- and postoperative BPI and the Nordlinger score systems can be used to predict survival for laparoscopically operated patients in the era of multimodal-treatment after adjusting of survival rates. The actual five- and 10-year survival after laparoscopic resection of CLM is similar to results previously published for open liver resection. J. Surg. Oncol. 2016;114:757-763. © 2016 Wiley Periodicals, Inc.
authors.affiliation: Intervention Centre, Oslo University Hospital - Rikshospitalet, Oslo, Norway. leonid.barkhatov@gmail.com.|Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway. leonid.barkhatov@gmail.com.
authors.forename: Leonid
authors.initials: L
authors.lastname: Barkhatov
authors.affiliation: Intervention Centre, Oslo University Hospital - Rikshospitalet, Oslo, Norway.|Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.|Department of Gastrointestinal and Hepatobiliary Surgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
authors.forename: Åsmund A
authors.initials: ÅA
authors.lastname: Fretland
authors.affiliation: Intervention Centre, Oslo University Hospital - Rikshospitalet, Oslo, Norway.|Department of Gastrointestinal Surgery, Akershus University Hospital, Lørenskog, Norway.|Surgical Department, Finnmark Hospital, Kirkenes, Norway.
authors.forename: Airazat M
authors.initials: AM
authors.lastname: Kazaryan
authors.affiliation: Department of Gastrointestinal and Hepatobiliary Surgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
authors.forename: Bård I
authors.initials: BI
authors.lastname: Røsok
authors.affiliation: Department of Gastrointestinal and Hepatobiliary Surgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
authors.forename: Kristoffer W
authors.initials: KW
authors.lastname: Brudvik
authors.affiliation: Department of Gastrointestinal and Hepatobiliary Surgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
authors.forename: Anne
authors.initials: A
authors.lastname: Waage
authors.affiliation: Department of Gastrointestinal and Hepatobiliary Surgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
authors.forename: Bjørn A
authors.initials: BA
authors.lastname: Bjørnbeth
authors.affiliation: Intervention Centre, Oslo University Hospital - Rikshospitalet, Oslo, Norway.|Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.
authors.forename: Mushegh A
authors.initials: MA
authors.lastname: Sahakyan
authors.affiliation: Intervention Centre, Oslo University Hospital - Rikshospitalet, Oslo, Norway.|Institute of Clinical Medicine, Medical Faculty, University of Oslo, Oslo, Norway.|Department of Gastrointestinal and Hepatobiliary Surgery, Oslo University Hospital - Rikshospitalet, Oslo, Norway.
authors.forename: Bjørn
authors.initials: B
authors.lastname: Edwin
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015179:Colorectal Neoplasms / Q000473:pathology*; D016208:Databases, Factual; D003661:Decision Support Techniques; D005260:Female; D005500:Follow-Up Studies; D006498:Hepatectomy / Q000379:methods; D006801:Humans; D010535:Laparoscopy; D008113:Liver Neoplasms / Q000401:mortality / Q000556:secondary* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D011379:Prognosis; D012189:Retrospective Studies; D018570:Risk Assessment; D016019:Survival Analysis; D016896:Treatment Outcome
keywords: clinical risk scores; colorectal liver metastases; laparoscopic liver resection