title: Analysis of HTLV-I in Hodgkin's Disease.
abstract: Both Epstein-Barr virus (EBV) and the human T-cell leukemia virus I (HTLV-I) have been implicated in the generation of human lymphoproliferative disorders such as Burkitt's lymphoma, Hodgkin's disease (HD) and acute T-cell leukemia (ATL). In Hodgkin's disease EBV has been recently detected in Hodgkin's and Sternberg-Reed cells in about 20% of the cases. We analysed if HTLV-I is also involved in Hodgkin's disease by using Northern Blot analysis and the polymerase chain reaction (PCR). In our experiments we did not detect HTLV-I specific sequences in HD derived cell lines or in primary specimens.
authors.affiliation: a I. Medizinische Klinik, Universität Köln, Göttingen, FRG.
authors.forename: H
authors.initials: H
authors.lastname: Tesch
authors.affiliation: a I. Medizinische Klinik, Universität Köln, Göttingen, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Jücker
authors.affiliation: b Max-Planck-Gesellschaft für klinische Forschung, Göttingen, FRG.
authors.forename: M
authors.initials: M
authors.lastname: Krönke
authors.affiliation: a I. Medizinische Klinik, Universität Köln, Göttingen, FRG.
authors.forename: V
authors.initials: V
authors.lastname: Diehl
keywords: HTLV-I; Hodgkin and Sternberg Reed cells; Hodgkin's disease