title: Association of obesity with hypertension and dyslipidemia in type 2 diabetes mellitus subjects.
abstract: OBJECTIVE
  Obesity and diabetes are contributed to cardiovascular disease risk. The current study was performed to evaluate the association of central and general obesity and cardio-metabolic risk factors, including dyslipidemia and hypertension in T2DM patients.
  
  
  METHODS
  This was a cross-sectional study in T2DM adults. Body mass index (BMI) was used to identify general obesity and waist circumference (WC) was measured to define abdominal obesity (based on ATP III). Biochemical analyses, and anthropometric and blood pressure measurements were done for all participants.
  
  
  RESULTS
  Participants with central obesity showed significantly higher systolic (132.5mmHg vs. 125.4mmHg, p=0.024) and diastolic blood pressures (84.9mmHg vs. 80mmHg, p=0.007) than participants without obesity. Dyslipidemia was more prevalent in all participants either by BMI (98.3% vs. 97%, 95% CI: 0.18-17.53) or by WC (97.2% vs. 98%, 95% CI: 0.07-7.19). Abdominal adiposity in diabetic subjects showed significant reverse association with high level of physical activity (OR=0.22, 95% CI: 0.06-0.85). Hypertriglyceridemia rate was increased with both central (OR=2.11; p=0.040) and general obesity (OR=2.68; p=0.021). After adjustment for energy intake and age, females had higher risk of general (OR=4.57, 95% CI=1.88-11.11) and central obesity (OR=7.93, 95% CI=3.48-18.08).
  
  
  CONCLUSIONS
  Females were more susceptible to obesity. Hypertension was associated with both obesity measures. Dyslipidemia, except for hypertriglyceridemia, was correlated to neither abdominal nor general obesity.
authors.affiliation: Department of Nutrition, Faculty of Arvand International Division, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: Raziehanari85@yahoo.com.
authors.forename: Razieh
authors.initials: R
authors.lastname: Anari
authors.affiliation: Health Research Institute, Diabetes Research Center, Department of Nutrition, School of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: amani-r@ajums.ac.ir.
authors.forename: Reza
authors.initials: R
authors.lastname: Amani
authors.affiliation: Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: sml1381@yahoo.com.
authors.forename: Seyed Mahmoud
authors.initials: SM
authors.lastname: Latifi
authors.affiliation: Health Research Institute, Nutrition and Metabolic Disease Research Center, Department of Nutrition, School of Paramedicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: m_veissi@yahoo.com.
authors.forename: Masoud
authors.initials: M
authors.lastname: Veissi
authors.affiliation: Health Research Institute, Diabetes Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address: hjb_shahbazian@yahoo.com.
authors.forename: Hajieh
authors.initials: H
authors.lastname: Shahbazian
mesh_terms: D000328:Adult; D000368:Aged; D000886:Anthropometry; D015415:Biomarkers / Q000032:analysis; D015992:Body Mass Index; D003430:Cross-Sectional Studies; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000209:etiology / Q000378:metabolism; D050171:Dyslipidemias / Q000150:complications / Q000453:epidemiology*; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D006973:Hypertension / Q000150:complications / Q000453:epidemiology*; D007492:Iran / Q000453:epidemiology; D008297:Male; D008875:Middle Aged; D009765:Obesity / Q000503:physiopathology*; D015995:Prevalence; D011379:Prognosis; D012307:Risk Factors; D055105:Waist Circumference
chemical_list: D015415:Biomarkers
keywords: Central obesity; Dyslipidemia; General obesity; Hypertension; T2DM