title: BH3 profiling as a tool to identify acquired resistance to venetoclax in multiple myeloma.
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Christelle
authors.initials: C
authors.lastname: Dousset
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Sophie
authors.initials: S
authors.lastname: Maïga
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Patricia
authors.initials: P
authors.lastname: Gomez-Bougie
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Joy
authors.initials: J
authors.lastname: Le Coq
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Cyrille
authors.initials: C
authors.lastname: Touzeau
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Philippe
authors.initials: P
authors.lastname: Moreau
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Steven
authors.initials: S
authors.lastname: Le Gouill
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: David
authors.initials: D
authors.lastname: Chiron
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Catherine
authors.initials: C
authors.lastname: Pellat-Deceunynck
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Agnès
authors.initials: A
authors.lastname: Moreau-Aubry
authors.affiliation: CRCNA, CNRS, INSERM, Centre Hospitalier Universitaire de Nantes, Université d'Angers, Université de Nantes, Nantes, France.
authors.forename: Martine
authors.initials: M
authors.lastname: Amiot
mesh_terms: D000970:Antineoplastic Agents / Q000494:pharmacology* / Q000627:therapeutic use; D014408:Biomarkers, Tumor; D019086:Bridged Bicyclo Compounds, Heterocyclic / Q000494:pharmacology* / Q000627:therapeutic use; D019008:Drug Resistance, Neoplasm / Q000235:genetics*; D020869:Gene Expression Profiling; D006801:Humans; D008545:Melanoma / Q000175:diagnosis / Q000188:drug therapy / Q000235:genetics*; D018716:Molecular Mimicry; D054730:Protein Interaction Domains and Motifs; D013449:Sulfonamides / Q000494:pharmacology* / Q000627:therapeutic use
chemical_list: D000970:Antineoplastic Agents; D014408:Biomarkers, Tumor; D019086:Bridged Bicyclo Compounds, Heterocyclic; D013449:Sulfonamides; C579720:venetoclax
keywords: BCL2 family members; Venetoclax; apoptosis; resistance