title: Effect of macular hole volume on postoperative central macular thickness.
abstract: OBJECTIVE
  To evaluate the association between macular hole volume (MHV) and postoperative central macular thickness (CMT) using spectral-domain optical coherence tomography (SD-OCT).
  
  
  METHODS
  Thirty-three eyes of 30 patients with a large full-thickness idiopathic macular hole with or without vitreomacular traction who underwent surgical intervention were included in this cross-sectional study. Complete ophthalmological examination, including SD-OCT, was performed for all participants during the pre- and postoperative visits. MHV was preoperatively measured using SD-OCT, which captured the widest cross-sectional image of the hole. For normal distribution analysis of the data, the Kolmogorov-Smirnov test was performed, and for statistical analyses, chi-square, Student's t-test, Mann-Whitney U test, and Pearson's correlation coefficient test were performed.
  
  
  RESULTS
  Mean preoperative best-corrected visual acuity (BCVA) and MHV were found to be 0.99 ± 0.36 (range, 0.3-2.0) logMAR and 0.139 ± 0.076 (range, 0.004-0.318) mm3, respectively. Mean follow-up was 16.3 ± 14.3 (range, 3-50) months. No statistical correlations were found between MHV and postoperative BCVA (p=0.588) and between MHV and disease recurrence (p=0.544). A weak negative correlation existed between MHV and final CMT scores (p=0.04, r=-0.383).
  
  
  CONCLUSIONS
  Greater MHV was found to be weakly associated with lower postoperative CMT scores.
authors.affiliation: Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
authors.forename: Taylan
authors.initials: T
authors.lastname: Ozturk
authors.affiliation: Department of Ophthalmology, Sifa University, Izmir, Turkey.
authors.forename: Eyyup
authors.initials: E
authors.lastname: Karahan
authors.affiliation: Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
authors.forename: Duygu
authors.initials: D
authors.lastname: Er
authors.affiliation: Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
authors.forename: Mahmut
authors.initials: M
authors.lastname: Kaya
authors.affiliation: Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
authors.forename: Nilufer
authors.initials: N
authors.lastname: Kocak
authors.affiliation: Department of Ophthalmology, Dokuz Eylul University School of Medicine, Izmir, Turkey.
authors.forename: Suleyman
authors.initials: S
authors.lastname: Kaynak
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D019412:Anatomy, Cross-Sectional; D003430:Cross-Sectional Studies; D005260:Female; D006801:Humans; D007429:Intraocular Pressure; D008266:Macula Lutea / Q000473:pathology* / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D009929:Organ Size; D011184:Postoperative Period; D057234:Preoperative Period; D012016:Reference Values; D012167:Retinal Perforations / Q000473:pathology* / Q000601:surgery*; D018709:Statistics, Nonparametric; D013997:Time Factors; D041623:Tomography, Optical Coherence / Q000379:methods; D016896:Treatment Outcome; D014792:Visual Acuity; D055815:Young Adult