title: [Systematic review of feasibility, safety and efficacy of ex situ liver resection and autotransplantation].
abstract: OBJECTIVE
  To evaluate the feasibility, safety and efficiency of ex situ liver resection (ESLR)technique in patients with hepatocaval region involvement.
  
  
  METHODS
  A systematic research of the data bases CNKI, Wan Fang, CQVIP, PubMed, CENTRAL, Medline, Embase, Cochrane, International Clinical Transplantation Registration Platform and Transplant Library was performed. All the current data regarding the feasibility, safety, and oncological efficiency of ESLR was systematically reviewed. Feasibility, conversion to allo-transplantation rate, complication and 90-day mortality were analyzed.
  
  
  RESULTS
  A literature search revealed a total of 46 publications with 191 patients who underwent ex situ liver resection (101 autotransplantation, 90 ante-situm liver resection). The most common indication was hepatocellular carcinoma (49), followed by colorectal liver metastasis (37), hepatic alveolar echinococcosis (33) and cholangiocarcinoma (26). The feasibility rate was 84.5% (CI=76.6%-90.1%), the conversion to allo-transplantation rate was 13.5% (CI=8.5%-21.0%). Overall complication rate was 58.1% (CI=48.5%-67.1%), and complications grade Ⅲa or higher occurred in 43.1% (CI=33.6%-53.1%).90-day mortality was 19.5% (CI=12.7%-28.8%).
  
  
  CONCLUSIONS
  ESLR and autotransplantation technique is an effective surgical approach for hepatic tumor with hepatocaval region involvement. Strict control of surgical indications, preoperative evaluation and precise surgical technique is essential to success.
authors.affiliation: Liver Transplantation & Laparoscopic Surgery Department, Hepatobiallary & Hydatid disease Dept. Digestive & Vascular Surgery Center, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
authors.forename: Tehj
authors.initials: T
authors.lastname: Tuxun
authors.forename: Abdslm
authors.initials: A
authors.lastname: Aini
authors.forename: Y P
authors.initials: YP
authors.lastname: Li
authors.forename: Sdk
authors.initials: S
authors.lastname: Apaer
authors.forename: H
authors.initials: H
authors.lastname: Zhang
authors.forename: T
authors.initials: T
authors.lastname: Li
authors.forename: Tegal
authors.initials: T
authors.lastname: Aji
authors.forename: Ysf
authors.initials: Y
authors.lastname: Yimiti
authors.forename: J M
authors.initials: JM
authors.lastname: Zhao
authors.forename: Y M
authors.initials: YM
authors.lastname: Shao
authors.forename: H
authors.initials: H
authors.lastname: Wen
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000601:surgery; D018281:Cholangiocarcinoma; D015179:Colorectal Neoplasms / Q000601:surgery; D006498:Hepatectomy; D006801:Humans; D008099:Liver / Q000601:surgery*; D008113:Liver Neoplasms / Q000601:surgery*; D016031:Liver Transplantation; D012449:Safety; D014182:Transplantation, Autologous