title: Internal and External Validation of a Computer-Assisted Surveillance System for Hospital-Acquired Infections in a 754-Bed General Hospital in the Netherlands.
abstract: OBJECTIVE To evaluate a computer-assisted point-prevalence survey (CAPPS) for hospital-acquired infections (HAIs). DESIGN Validation cohort. SETTING A 754-bed teaching hospital in the Netherlands. METHODS For the internal validation of a CAPPS for HAIs, 2,526 patients were included. All patient records were retrospectively reviewed in depth by 2 infection control practitioners (ICPs) to determine which patients had suffered an HAI. Preventie van Ziekenhuisinfecties door Surveillance (PREZIES) criteria were used. Following this internal validation, 13 consecutive CAPPS were performed in a prospective study from January to March 2013 to determine weekly, monthly, and quarterly HAI point prevalence. Finally, a CAPPS was externally validated by PREZIES (Rijksinstituut voor Volksgezondheid en Milieu [RIVM], Bilthoven, Netherlands). In all evaluations, discrepancies were resolved by consensus. RESULTS In our series of CAPPS, 83% of the patients were automatically excluded from detailed review by the ICP. The sensitivity of the method was 91%. The time spent per hospital-wide CAPPS was ~3 hours. External validation showed a negative predictive value of 99.1% for CAPPS. CONCLUSIONS CAPPS proved to be a sensitive, accurate, and efficient method to determine serial weekly point-prevalence HAI rates in our hospital. Infect Control Hosp Epidemiol 2016;1-6.
authors.affiliation: 1Erasmus University Medical Center (Erasmus MC),Rotterdam,Netherlands.
authors.forename: H Roel A
authors.initials: HR
authors.lastname: Streefkerk
authors.affiliation: 4Ziekenhuisgroep Twente,Almelo/Hengelo,Netherlands.
authors.forename: Ivar O
authors.initials: IO
authors.lastname: Lede
authors.affiliation: 1Erasmus University Medical Center (Erasmus MC),Rotterdam,Netherlands.
authors.forename: John L V
authors.initials: JL
authors.lastname: Eriksson
authors.affiliation: 4Ziekenhuisgroep Twente,Almelo/Hengelo,Netherlands.
authors.forename: Marije G
authors.initials: MG
authors.lastname: Meijling
authors.affiliation: 1Erasmus University Medical Center (Erasmus MC),Rotterdam,Netherlands.
authors.forename: Conrad P
authors.initials: CP
authors.lastname: van der Hoeven
authors.affiliation: 6National Institute for Public Health and the Environment,Center for Infectious Disease Control Bilthoven,Netherlands.
authors.forename: Jan C
authors.initials: JC
authors.lastname: Wille
authors.affiliation: 6National Institute for Public Health and the Environment,Center for Infectious Disease Control Bilthoven,Netherlands.
authors.forename: Titia E M
authors.initials: TE
authors.lastname: Hopmans
authors.affiliation: 7Department of Medical Microbiology,University of Groningen,University Medical Center Groningen,Groningen,Netherlands.
authors.forename: Alex W
authors.initials: AW
authors.lastname: Friedrich
authors.affiliation: 1Erasmus University Medical Center (Erasmus MC),Rotterdam,Netherlands.
authors.forename: Henri A
authors.initials: HA
authors.lastname: Verbrugh
authors.affiliation: 4Ziekenhuisgroep Twente,Almelo/Hengelo,Netherlands.
authors.forename: Nashwan Al
authors.initials: NA
authors.lastname: Naiemi
mesh_terms: D000465:Algorithms; D015331:Cohort Studies; D003428:Cross Infection / Q000175:diagnosis / Q000453:epidemiology*; D003658:Decision Making, Computer-Assisted; D003661:Decision Support Techniques; D006769:Hospitals, General; D006801:Humans; D016357:Infection Control Practitioners; D007407:Interviews as Topic; D008499:Medical Records; D009426:Netherlands / Q000453:epidemiology; D015995:Prevalence; D018571:Sentinel Surveillance