title: Sensitive SERS detection of miRNA via enzyme-free DNA machine signal amplification.
abstract: In this work, an enzyme-free signal amplified detection platform is described for miRNA detection with a DNA fueled molecular machine. Coupling SERS technology with multiple amplification modes, this flexible biosensing system exhibits high sensitivity and specificity.
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China. xiliangluo@qust.edu.cn yesujuan@126.com.
authors.forename: Xiaoxiao
authors.initials: X
authors.lastname: Li
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China. xiliangluo@qust.edu.cn yesujuan@126.com.
authors.forename: Sujuan
authors.initials: S
authors.lastname: Ye
authors.affiliation: Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, P. R. China. xiliangluo@qust.edu.cn yesujuan@126.com.
authors.forename: Xiliang
authors.initials: X
authors.lastname: Luo
mesh_terms: D015374:Biosensing Techniques; D045744:Cell Line, Tumor; D004247:DNA / Q000737:chemistry*; D006801:Humans; D035683:MicroRNAs / Q000032:analysis* / Q000235:genetics; D021141:Nucleic Acid Amplification Techniques; D013059:Spectrum Analysis, Raman
chemical_list: D035683:MicroRNAs; D004247:DNA