title: A Microarray Tool Provides Pathway and GO Term Analysis.
abstract: Analysis of gene expression profiles is no longer exclusively a task for bioinformatic experts. However, gaining statistically significant results is challenging and requires both biological knowledge and computational know-how. Here we present a novel, user-friendly microarray reporting tool called maRt. The software provides access to bioinformatic resources, like gene ontology terms and biological pathways by use of the DAVID and the BioMart web-service. Results are summarized in structured HTML reports, each presenting a different layer of information. In these report, contents of diverse sources are integrated and interlinked. To speed up processing, maRt takes advantage of the multi-core technology of modern desktop computers by using parallel processing. Since the software is built upon a RCP infrastructure it might be an outset for developers aiming to integrate novel R based applications.
  
  
  BACKGROUND
  Installer, documentation and various kinds of tutorials are available under LGPL license at the website of our institute http://www.pharma.uni-bonn.de/www/mart. This software is free for academic use.
authors.affiliation: Institute of Pharmaceutical Chemistry II, University of Bonn an der Immenburg 4, 53121 Bonn phone: 0228735210. martin.koch@uni-bonn.de.
authors.forename: Martin
authors.initials: M
authors.lastname: Koch
authors.affiliation: Institute of Human Genetics and Anthropology, University of Düsseldorf, Universitätsstr. 1, 40225, Düsseldorf.|Center of Advanced European Studies and Research (Caesar), Ludwig-Erhard-Allee 2, 53175 Bonn.
authors.forename: Hans-Dieter
authors.initials: HD
authors.lastname: Royer
authors.affiliation: Institute of Pharmaceutical Chemistry II, University of Bonn an der Immenburg 4, 53121 Bonn phone: 0228735210.
authors.forename: Michael
authors.initials: M
authors.lastname: Wiese
keywords: Bioinformatics; Genomics; Medicinal chemistry