title: Physical activity is associated with reduced fatigue in adults living with HIV/AIDS.
abstract: OBJECTIVE
  The aim of this study was to describe the relationships among home-based physical activity, fatigue, sleep, gender and quality of life in people living with HIV/AIDS BACKGROUND: Fatigue is a common and distressing symptom among people living with HIV/AIDS. Few interventions exist that effectively reduce fatigue in this population. Physical activity has shown promise to reduce fatigue in other populations, but its impact on fatigue in HIV/AIDS has not yet been explored.
  
  
  METHODS
  This study was conducted using a prospective, descriptive cohort design.
  
  
  METHODS
  Overall, 90 adults living with HIV/AIDS completed cross-sectional measures. Home-based physical activity was measured using a 7-day self-report diary. Fatigue was measured using the self-reported HIV-Related Fatigue Scale. Sleep was assessed using wrist actigraphy and quality of life was assessed using the HIV-Associated Quality of Life Scale. Data were collected from December 2012-April 2013 and analysed using correlations and multiple linear regression.
  
  
  RESULTS
  The number of minutes of home-based physical activity was significantly associated with reduced fatigue among people living with HIV/AIDS. In addition, increased fatigue was associated with decreased quality of life. No associations were found among fatigue, sleep or gender.
  
  
  CONCLUSIONS
  Our study demonstrates that physical activity in the home setting is an effective strategy to reduce fatigue among people living with HIV/AIDS. Future work developing and testing interventions to improve home-based physical activity in this population is needed.
authors.affiliation: Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: Allison R
authors.identifier: http://orcid.org/0000-0002-7538-5780
authors.initials: AR
authors.lastname: Webel
authors.affiliation: Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: Joe
authors.identifier: http://orcid.org/0000-0002-9893-5247
authors.initials: J
authors.lastname: Perazzo
authors.affiliation: Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: Michael
authors.initials: M
authors.lastname: Decker
authors.affiliation: Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: Christine
authors.initials: C
authors.lastname: Horvat-Davey
authors.affiliation: School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: Abdus
authors.initials: A
authors.lastname: Sattar
authors.affiliation: Sarah Cole Hirsh Center for Evidence-Based Practice, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, Ohio, USA.
authors.forename: Joachim
authors.initials: J
authors.lastname: Voss
mesh_terms: D000163:Acquired Immunodeficiency Syndrome / Q000628:therapy*; D000328:Adult; D003430:Cross-Sectional Studies; D015444:Exercise; D005221:Fatigue; D005260:Female; D015658:HIV Infections / Q000628:therapy*; D006801:Humans; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D011788:Quality of Life
keywords: HIV/AIDS; fatigue; nurses; nursing; sleep; symptom management