title: Epidemiologic studies and novel clinical research approaches that impact TB vaccine development.
abstract: The 4th Global Forum on TB Vaccines, convened in Shanghai, China, from 21 - 24 April 2015, brought together a wide and diverse community involved in tuberculosis vaccine research and development to discuss the current status of, and future directions for this critical effort. This paper summarizes the sessions on Developing TB Vaccines for Prevention of Disease, Prevention of Infection, and Immunotherapy Indications; Concepts and Approaches in Clinical Research & Development; and Epidemiological Research. Summaries of all sessions from the 4th Global Forum are compiled in a special supplement of Tuberculosis.
authors.affiliation: Aeras, Rockville, MD, USA. Electronic address: tevans@aeras.org.
authors.forename: Thomas G
authors.initials: TG
authors.lastname: Evans
authors.affiliation: Aurum Research Institute, Johannesburg, South Africa; School of Public Health, University of Witwatersrand, South Africa.
authors.forename: Gavin J
authors.initials: GJ
authors.lastname: Churchyard
authors.affiliation: South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease & Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
authors.forename: Adam
authors.initials: A
authors.lastname: Penn-Nicholson
authors.affiliation: Aeras, Beijing, China.
authors.forename: Chen
authors.initials: C
authors.lastname: Chen
authors.affiliation: Fudan University, Shanghai, China; Heidelberg University, Heidelberg, Germany.
authors.forename: Xu
authors.initials: X
authors.lastname: Gao
authors.affiliation: Aeras, Cape Town, South Africa.
authors.forename: Dereck R
authors.initials: DR
authors.lastname: Tait
authors.affiliation: South African Tuberculosis Vaccine Initiative, Institute of Infectious Disease & Molecular Medicine and Division of Immunology, Department of Pathology, University of Cape Town, Cape Town, South Africa.
authors.forename: Mark
authors.initials: M
authors.lastname: Hatherill
mesh_terms: D001500:BCG Vaccine; D055808:Drug Discovery; D004812:Epidemiologic Methods; D006801:Humans; D055502:Secondary Prevention; D014376:Tuberculosis / Q000453:epidemiology / Q000517:prevention & control*; D032581:Tuberculosis Vaccines
chemical_list: D001500:BCG Vaccine; D032581:Tuberculosis Vaccines
keywords: Clinical trial; Epidemiology; Tuberculosis