title: Autoimmune Pancreatitis: A Multiorgan Disease Presenting a Conundrum for Clinicians in the West.
abstract: Autoimmune pancreatitis (AIP), a clinical entity originally described in East Asia and more recently recognized in the United States and Europe, poses a diagnostic conundrum for clinicians in the West due to immunoglobulin G4 seronegativity. Although expert panels classify this disease into 2 types, it remains difficult to stratify the disease given that both types share most clinical, biochemical, and imaging characteristics. The classic presentation of AIP can mimic that of pancreatic carcinoma, which increases the urgency of evaluation, diagnosis, and treatment. In this article, we elucidate the differences between the 2 types of AIP, highlight the shortcomings of the current classification system, and propose a more inclusive view of the disorder.
authors.affiliation: All of the authors are affiliated with Mount Sinai Beth Israel in New York, New York. Dr Kim and Dr Voaklander are residents in the Department of Internal Medicine. Dr Mannan is a resident in the Department of Pathology. Dr Kasmin, Dr Brown, and Dr Siegel are attending physicians in the Department of Internal Medicine and codirectors of the Advanced Fellowship in Therapeutic Endoscopy. Dr Siegel is also a clinical professor of medicine at the Icahn School of Medicine at Mount Sinai in New York, New York.
authors.forename: Eileen
authors.initials: E
authors.lastname: Kim
authors.affiliation: All of the authors are affiliated with Mount Sinai Beth Israel in New York, New York. Dr Kim and Dr Voaklander are residents in the Department of Internal Medicine. Dr Mannan is a resident in the Department of Pathology. Dr Kasmin, Dr Brown, and Dr Siegel are attending physicians in the Department of Internal Medicine and codirectors of the Advanced Fellowship in Therapeutic Endoscopy. Dr Siegel is also a clinical professor of medicine at the Icahn School of Medicine at Mount Sinai in New York, New York.
authors.forename: Rebecca
authors.initials: R
authors.lastname: Voaklander
authors.affiliation: All of the authors are affiliated with Mount Sinai Beth Israel in New York, New York. Dr Kim and Dr Voaklander are residents in the Department of Internal Medicine. Dr Mannan is a resident in the Department of Pathology. Dr Kasmin, Dr Brown, and Dr Siegel are attending physicians in the Department of Internal Medicine and codirectors of the Advanced Fellowship in Therapeutic Endoscopy. Dr Siegel is also a clinical professor of medicine at the Icahn School of Medicine at Mount Sinai in New York, New York.
authors.forename: Franklin E
authors.initials: FE
authors.lastname: Kasmin
authors.affiliation: All of the authors are affiliated with Mount Sinai Beth Israel in New York, New York. Dr Kim and Dr Voaklander are residents in the Department of Internal Medicine. Dr Mannan is a resident in the Department of Pathology. Dr Kasmin, Dr Brown, and Dr Siegel are attending physicians in the Department of Internal Medicine and codirectors of the Advanced Fellowship in Therapeutic Endoscopy. Dr Siegel is also a clinical professor of medicine at the Icahn School of Medicine at Mount Sinai in New York, New York.
authors.forename: William H
authors.initials: WH
authors.lastname: Brown
authors.affiliation: All of the authors are affiliated with Mount Sinai Beth Israel in New York, New York. Dr Kim and Dr Voaklander are residents in the Department of Internal Medicine. Dr Mannan is a resident in the Department of Pathology. Dr Kasmin, Dr Brown, and Dr Siegel are attending physicians in the Department of Internal Medicine and codirectors of the Advanced Fellowship in Therapeutic Endoscopy. Dr Siegel is also a clinical professor of medicine at the Icahn School of Medicine at Mount Sinai in New York, New York.
authors.forename: Rifat
authors.initials: R
authors.lastname: Mannan
authors.affiliation: All of the authors are affiliated with Mount Sinai Beth Israel in New York, New York. Dr Kim and Dr Voaklander are residents in the Department of Internal Medicine. Dr Mannan is a resident in the Department of Pathology. Dr Kasmin, Dr Brown, and Dr Siegel are attending physicians in the Department of Internal Medicine and codirectors of the Advanced Fellowship in Therapeutic Endoscopy. Dr Siegel is also a clinical professor of medicine at the Icahn School of Medicine at Mount Sinai in New York, New York.
authors.forename: Jerome H
authors.initials: JH
authors.lastname: Siegel
keywords: Autoimmune pancreatitis; endoscopic retrograde cholangiopancreatography; endoscopic ultrasound; fine-needle aspiration; magnetic resonance cholangiopancreatography; seronegative; seropositive