title: Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities.
abstract: Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes in children is different not only from type 1 but also from type 2 diabetes in adults. Understanding the unique pathophysiology of type 2 diabetes in youth, as well as the risk of complications and the psychosocial impact, will enable industry, academia, funding agencies, advocacy groups, and regulators to collectively evaluate both current and future research, treatment, and prevention approaches. This Consensus Report characterizes type 2 diabetes in children, evaluates the fundamental differences between childhood and adult disease, describes the current therapeutic options, and discusses challenges to and approaches for developing new treatments.
authors.affiliation: Department of Pediatrics, University of Colorado School of Medicine, and Department of Endocrinology, Children's Hospital Colorado, Aurora, CO.
authors.forename: Kristen J
authors.initials: KJ
authors.lastname: Nadeau
authors.affiliation: Section of Psychology, Department of Pediatrics, Baylor College of Medicine Education at Texas Children's Hospital, Houston, TX.
authors.forename: Barbara J
authors.initials: BJ
authors.lastname: Anderson
authors.affiliation: American Diabetes Association, Alexandria, VA.
authors.forename: Erika G
authors.initials: EG
authors.lastname: Berg
authors.affiliation: American Diabetes Association, Alexandria, VA.
authors.forename: Jane L
authors.initials: JL
authors.lastname: Chiang
authors.affiliation: Clinical Development, Daiichi Sankyo, New York, NY.
authors.forename: Hubert
authors.initials: H
authors.lastname: Chou
authors.affiliation: Department of Pediatrics and Harold Hamm Diabetes Center-Children's, The University of Oklahoma College of Medicine, Oklahoma City, OK.
authors.forename: Kenneth C
authors.initials: KC
authors.lastname: Copeland
authors.affiliation: Indiana University School of Medicine, Indianapolis, IN.
authors.forename: Tamara S
authors.initials: TS
authors.lastname: Hannon
authors.affiliation: School of Public Health, The City University of New York, New York, NY.
authors.forename: Terry T-K
authors.initials: TT
authors.lastname: Huang
authors.affiliation: The University of Texas Health Science Center at San Antonio, San Antonio, TX.
authors.forename: Jane L
authors.initials: JL
authors.lastname: Lynch
authors.affiliation: Pediatrics and Community Health, Northern Navajo Medical Center, Navajo Area Indian Health Service, Shiprock, NM.
authors.forename: Jeff
authors.initials: J
authors.lastname: Powell
authors.affiliation: Department of Pediatrics, Health Sciences Centre Winnipeg, Winnipeg, Canada.
authors.forename: Elizabeth
authors.initials: E
authors.lastname: Sellers
authors.affiliation: Department of Pediatric Endocrinology and Yale Center for Clinical Investigation, Yale School of Medicine, New Haven, CT.
authors.forename: William V
authors.initials: WV
authors.lastname: Tamborlane
authors.affiliation: Department of Pediatrics, University of Colorado School of Medicine, and Department of Endocrinology, Children's Hospital Colorado, Aurora, CO philip.zeitler@childrenscolorado.org.
authors.forename: Philip
authors.initials: P
authors.lastname: Zeitler
mesh_terms: D000293:Adolescent; D017668:Age of Onset; D052636:Allostasis; D002648:Child; D003695:Delivery of Health Care; D048909:Diabetes Complications / Q000453:epidemiology*; D003924:Diabetes Mellitus, Type 2 / Q000453:epidemiology* / Q000378:metabolism / Q000523:psychology / Q000628:therapy; D004035:Diet Therapy; D019468:Disease Management; D005006:Ethnicity / Q000706:statistics & numerical data; D005081:Exercise Therapy; D006801:Humans; D007004:Hypoglycemic Agents / Q000627:therapeutic use; D008913:Minority Groups / Q000706:statistics & numerical data; D012306:Risk; D040242:Risk Reduction Behavior; D012959:Socioeconomic Factors; D014481:United States / Q000453:epidemiology; D055815:Young Adult
chemical_list: D007004:Hypoglycemic Agents