title: The Impact of Hemodialysis and Arteriovenous Access Flow on Extracranial Hemodynamic Changes in End-Stage Renal Disease Patients.
abstract: In this study, we characterized cerebral blood flow changes by assessment of blood flow parameters in neck arteries using carotid duplex ultrasonography and predictive factors for these hemodynamic changes. Hemodynamic variables were measured before and during hemodialysis in 81 patients with an arteriovenous access in their arm. Hemodialysis produced significant lowering in peak systolic velocity and flow volume of neck arteries and calculated total cerebral blood flow (1,221.9 ± 344.9 [before hemodialysis] vs. 1,085.8 ± 319.2 [during hemodialysis], P < 0.001). Effects were greater in vessels on the same side as the arteriovenous access and these changes were influenced by arteriovenous access flow during hemodialysis, both in the CCA (r = -0.277, P = 0.015) and the VA (r = -0.239, P = 0.034). The change of total cerebral blood flow during hemodialysis was independently related with age, presence of diabetes, and systemic blood pressure.
authors.affiliation: Renal Division, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea .
authors.forename: Sarah
authors.identifier: 0000-0002-8184-8905
authors.initials: S
authors.lastname: Chung
authors.affiliation: Department of Neurology, Chungnam National University Hospital, Daejeon, Korea.; Daejeon-Chungnam Regional Cerebrovascular Center, Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Hye Seon
authors.identifier: 0000-0002-2031-5662
authors.initials: HS
authors.lastname: Jeong
authors.affiliation: Renal Division, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea .
authors.forename: Dae Eun
authors.identifier: 0000-0003-2870-3958
authors.initials: DE
authors.lastname: Choi
authors.affiliation: Department of Neurology, Chungnam National University Hospital, Daejeon, Korea.; Daejeon-Chungnam Regional Cerebrovascular Center, Chungnam National University Hospital, Daejeon, Korea.
authors.forename: Hee-Jung
authors.identifier: 0000-0001-9572-4105
authors.initials: HJ
authors.lastname: Song
authors.affiliation: Department of Neurology, Chungnam National University Hospital, Daejeon, Korea .
authors.forename: Young Gi
authors.identifier: 0000-0003-1194-507X
authors.initials: YG
authors.lastname: Lim
authors.affiliation: Department of Neurology, Chungnam National University Hospital, Daejeon, Korea .
authors.forename: Joo Yeon
authors.identifier: 0000-0001-6999-1701
authors.initials: JY
authors.lastname: Ham
authors.affiliation: Renal Division, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea .
authors.forename: Ki Ryang
authors.identifier: 0000-0002-0136-176X
authors.initials: KR
authors.lastname: Na
authors.affiliation: Renal Division, Department of Internal Medicine, Chungnam National University Hospital, Daejeon, Korea .
authors.forename: Kang Wook
authors.identifier: 0000-0003-3407-1205
authors.initials: KW
authors.lastname: Lee
mesh_terms: D000368:Aged; D002339:Carotid Arteries / Q000000981:diagnostic imaging; D002560:Cerebrovascular Circulation / Q000502:physiology*; D004244:Dizziness / Q000209:etiology; D005260:Female; D006439:Hemodynamics / Q000502:physiology*; D006801:Humans; D007676:Kidney Failure, Chronic / Q000503:physiopathology*; D008297:Male; D008875:Middle Aged; D006435:Renal Dialysis; D012307:Risk Factors; D018616:Ultrasonography, Doppler, Duplex
keywords: Arteriovenous Access; Carotid Duplex Ultrasonography; Cerebral Blood Flow; Hemodialysis