title: Diffusion-weighted MR imaging of non-complicated hepatic cysts: Value of 3T computed diffusion-weighted imaging.
abstract: OBJECTIVE
  To investigate the utility of computed 3T diffusion-weighted imaging (c-DWI) for the diagnosis of non-complicated hepatic cysts with a focus on the T2 shine-through effect.
  
  
  METHODS
  In 50 patients with non-complicated hepatic cysts we acquired one set of DWIs (b-value 0 and 1000 s/mm(2)) at 1.5T, and two sets at 3T (b-value 0 and 1000 s/mm(2), TE 70 ms; b-value 0 and 600 s/mm(2), TE 60 ms). We defined the original DWIs acquired with b = 1000 s/mm(2) at 1.5T and 3T as "o-1.5T-1000" and "o-3T-1000". c-DWIs were calculated with 3T DWI at b-values of 0 and 600 s/mm(2). c-DWI with b = 1000 and 1500 s/mm(2) were defined as "c-1000" and "c-1500". Radiologists evaluated the signal intensity (SI) of the cysts using a 3-point score where 1 = not visible, 2 = discernible, and 3 = clearly visible. They calculated the contrast ratio (CR) between the cysts and the surrounding liver parenchyma on each DWIs and recorded the apparent diffusion coefficient (ADC) with a b-value = 0 and 1000 s/mm(2) on 1.5T- and 3T DWIs.
  
  
  RESULTS
  Compared with o-1.5T-1000 DWI, the visual scores of all but the c-1500 DWIs were higher (p = 0.07 for c-1500- and p < 0.01 for the other DWIs). The CR at b = 1000 s/mm(2) was higher on o-3T-1000- than on o-1.5T-1000- (p < 0.01) but not higher than on c-1500 DWIs (p = 0.96). The CR at b = 0 s/mm(2) on 3T images with TE 70 ms was higher than on 1.5T images (p < 0.01). The ADC value was higher for 3T- than 1.5T images (p < 0.01).
  
  
  CONCLUSIONS
  Non-complicated hepatic cysts showed higher SI on o-3T-1000- than o-1.5T-1000 DWIs due to the T2-shine through effect. This high SI was suppressed on c-1500 DWIs.
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Yuko
authors.initials: Y
authors.lastname: Nakamura
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Toru
authors.initials: T
authors.lastname: Higaki
authors.affiliation: Department of Radiology, Hiroshima University Hospital, Hiroshima, Japan.
authors.forename: Yuji
authors.initials: Y
authors.lastname: Akiyama
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Wataru
authors.initials: W
authors.lastname: Fukumoto
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Kenji
authors.initials: K
authors.lastname: Kajiwara
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Yoko
authors.initials: Y
authors.lastname: Kaichi
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Yukiko
authors.initials: Y
authors.lastname: Honda
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Komoto
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Fuminari
authors.initials: F
authors.lastname: Tatsugami
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Makoto
authors.initials: M
authors.lastname: Iida
authors.affiliation: Radiology, Kure City Medical Association Hospital, Kure, Japan.
authors.forename: Toshifumi
authors.initials: T
authors.lastname: Ohmoto
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Shuji
authors.initials: S
authors.lastname: Date
authors.affiliation: Diagnostic Radiology, Hiroshima University, Hiroshima, Japan.
authors.forename: Kazuo
authors.initials: K
authors.lastname: Awai
keywords: ADC, apparent diffusion coefficient; CR, contrast ratio; Computed diffusion-weighted imaging; DWI, diffusion-weighted imaging; Diffusion-weighted imaging; Field strength; HCC, hepatocellular carcinoma; MRI, magnetic resonance imaging; Non-complicated hepatic cysts; SI, signal intensity; SNR, signal-to-noise ratio; T1-WI, T1-weighted MRI; T2 shine-through effect; T2-WI, T2-weighted MRI; c-DWI, computed diffusion-weighted imaging