title: Prognostic Factors in Patients who Underwent Aneurysmal Clipping due to Spontaneous Subarachnoid Hemorrhage.
abstract: OBJECTIVE
  Despite technical and medical advances, aneurysmal subarachnoid hemorrhages (SAH) continue to be a challenging pathology, associated with high rates of morbidity and mortality. In this regard, a definition is required of the various prognostic indicators of an SAH. The aim of the present retrospective study is to examine the various prognostic factors of the clinical outcomes of the patients who underwent a neurosurgical clipping of aneurysms due to aneurysmal SAH.
  
  
  METHODS
  The data of 104 patients that had suffered an aneurysmal SAH were analyzed. The baseline demographic, clinical and radiological data were all analyzed. The prognostic study was derived from an analysis of these variables. Relationship between prognostic factors and outcome was evaluated by univariate and logistic multivariate regression analysis.
  
  
  RESULTS
  This study has identified unfavorable outcomes on the Glasgow Outcome Scale at discharge after the surgical treatment of aneurysmal SAH associated with increased age, poor World Federation of Neurosurgical Societies (WFNS) grade on admission, higher Fisher's grade on admission computed tomography scan, larger aneurysm, and clinical vasospasm. In a multivariate logistic regression analysis, age, high WFNS grade, positive clinical vasospasm and size of aneurysm were found to be independent risk factors for mortality. The presence of hydrocephalus, number of aneurysms, positive risk factors, and the presence of Doppler vasospasm did not reach statistical significance.
  
  
  CONCLUSIONS
  The most important prognostic factors in patients undergoing surgery due to aneurysmal subarachnoid hemorrhage were WFNS grade, age, size of aneurysm and clinical vasospasm.
authors.affiliation: Haydarpasa Numune Training and Research Hospital, Department of Neurosurgery, Istanbul, Turkey.
authors.forename: Metin
authors.initials: M
authors.lastname: Orakdogen
authors.forename: Selin Tural
authors.initials: ST
authors.lastname: Emon
authors.forename: Hakan
authors.initials: H
authors.lastname: Somay
authors.forename: Taner
authors.initials: T
authors.lastname: Engin
authors.forename: Ozkan
authors.initials: O
authors.lastname: Ates
authors.forename: Mehmet Zafer
authors.initials: MZ
authors.lastname: Berkman
mesh_terms: D005260:Female; D006801:Humans; D002532:Intracranial Aneurysm / Q000150:complications / Q000601:surgery*; D008297:Male; D008875:Middle Aged; D019635:Neurosurgical Procedures / Q000401:mortality / Q000706:statistics & numerical data*; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D012720:Severity of Illness Index; D013345:Subarachnoid Hemorrhage / Q000209:etiology / Q000601:surgery*