title: Comparison of CT and MRI in Diagnosis of Laryngeal Carcinoma with Anterior Vocal Commissure Involvement.
abstract: This study aimed to compare the accuracy of CT and MRI in determining the invasion of thyroid cartilage by and the T staging of laryngeal carcinoma with anterior vocal commissure (AVC) involvement. A total of 26 cases of laryngeal carcinomas with AVC involvement from May 2012 to January 2014 underwent enhanced CT and MRI scan, out of whom 6 patients also underwent diffusion-weighted magnetic resonance imaging(DWI). T staging and thyroid cartilage involvement were evaluated. All the surgical specimens underwent serial section and were reviewed by two senior pathologists independently. When compared with pathologic staging, the accuracy was 88.46% (23/26) of MRI scan (with a 95% confidence interval 37~77%) and 57.69% (15/26) of CT scan (with a 95% confidence interval 70~98%), respectively (P < 0.01). We also reported three cases who were misdiagnosed on CT or MRI about either the thyroid cartilage was involved or not, and one case of preliminary study of DWI. Compared to CT, MRI exhibited a higher accuracy rate on T staging of laryngeal carcinomas with AVC involvement. Combined utility of CT and MRI could help improve the accuracy of assessment of thyroid cartilage involvement and T staging of laryngeal carcinomas with AVC involvement.
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.|The Otolaryngological Department, Meizhou People's Hospital, Meizhou, Guangdong, P.R. China.
authors.forename: Jian-Hui
authors.initials: JH
authors.lastname: Wu
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Jing
authors.initials: J
authors.lastname: Zhao
authors.affiliation: The Otolaryngological Department, Foshan People's Hospital, Foshan, Guangdong, P.R. China.
authors.forename: Zeng-Hong
authors.initials: ZH
authors.lastname: Li
authors.affiliation: The Otolaryngological Department, Peking University Shenzhen Hospital, Shenzhen, Guangdong, P.R. China.
authors.forename: Wei-Qiang
authors.initials: WQ
authors.lastname: Yang
authors.affiliation: The Otolaryngological Department, Futian People's Hospital, Shenzhen, Guangdong, P.R. China.
authors.forename: Qi-Hong
authors.initials: QH
authors.lastname: Liu
authors.affiliation: Department of Radiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Zhi-Yun
authors.initials: ZY
authors.lastname: Yang
authors.affiliation: Department of Pathology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Bing
authors.initials: B
authors.lastname: Liao
authors.affiliation: The Fourth People's Hospital of Shenzhen(Futian Hospital)Affiliated Futian Hospital of Guangdong Medical College, ShenZhen, Guangdong, P.R. China.
authors.forename: Xiao-Ling
authors.initials: XL
authors.lastname: Li
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Bin
authors.initials: B
authors.lastname: Wang
authors.affiliation: The Otolaryngological Department, Foshan People's Hospital, Foshan, Guangdong, P.R. China.
authors.forename: Hao
authors.initials: H
authors.lastname: Qin
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Jie
authors.initials: J
authors.lastname: Luo
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Ke-Xing
authors.initials: KX
authors.lastname: Lv
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Wei-Ping
authors.initials: WP
authors.lastname: Wen
authors.affiliation: Otorhinolaryngology Institute at Otorhinolaryngology Hospital, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, P.R. China.
authors.forename: Wen-Bin
authors.initials: WB
authors.lastname: Lei
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002277:Carcinoma / Q000000981:diagnostic imaging* / Q000473:pathology; D038524:Diffusion Magnetic Resonance Imaging; D006801:Humans; D007091:Image Processing, Computer-Assisted; D007822:Laryngeal Neoplasms / Q000000981:diagnostic imaging* / Q000473:pathology; D008297:Male; D008875:Middle Aged; D015203:Reproducibility of Results; D013957:Thyroid Cartilage / Q000000981:diagnostic imaging* / Q000473:pathology; D014057:Tomography, X-Ray Computed; D014827:Vocal Cords / Q000000981:diagnostic imaging / Q000473:pathology