title: Electrospray ionization mass spectrometric detection of low polar compounds by adding NaAuCl4.
abstract: Liquid chromatography electrospray ionization mass spectrometry (LC/ESI/MS) has been widely used for various analyses. However, it is difficult to use LC/ESI/MS for the analysis of low polar compounds, such as polycyclic aromatic hydrocarbons. It is well known that AuCl4-ion decomposes to AuCl3by heating, and AuCl3is a strong π-electrophilic Lewis acid. Low polar compounds (pyrene, benzo[a]pyrene, perylene, benzo[ghi]perylene, dibenzothiophene and p-dimethoxybenzene) were detected by ESI/MS in the positive ion mode by adding NaAuCl4. The low polar compound interacts with AuCl3formed at the ESI interface, and undergoes electron transfer to AuCl3. The radical cation of the low polar compound was then detected by MS. In addition, the LC/ESI/MS determination of polycyclic aromatic hydrocarbons by the post-column addition of NaAuCl4was studied. © 2016 The Authors Journal of Mass Spectrometry Published by John Wiley & Sons Ltd.
authors.affiliation: Shinshu University, Faculty of Textile Science and Technology, Division of Applied Biology, 3-15-1, Tokida, Ueda, 386-8567, Japan. moriwaki@shinshu-u.ac.jp.|Shinshu University, Division of Instrumental Analysis (Ueda branch), Research Center for Supports to Advanced Science, 3-15-1, Tokida, Ueda, 386-8567, Japan. moriwaki@shinshu-u.ac.jp.
authors.forename: Hiroshi
authors.initials: H
authors.lastname: Moriwaki
keywords: electrospray ionization; low polar compounds; polycyclic aromatic hydrocarbons; post-column addition; sodium chloroaurate