title: [Proliferative Vitreoretinopathy: Therapeutic Strategies].
abstract: BACKGROUND
  Development of proliferative vitreoretinopathy (PVR) is one of the most important complications of vitreoretinal surgery. Reaching the decision to treat and surgical treatment itself are both challenging.
  
  
  METHODS
  Our own data and a review of the literature in PubMed are summarised.
  
  
  RESULTS
  Pharmacological approaches to the prevention and treatment of proliferative vitreoretinopathy have been limited to concepts that have been investigated in preclinical and a few clinical studies. Anti-inflammatory and antiproliferative substances may be mentioned in this context. Surgical techniques range from scleral buckling to the gold standard pars plana vitrectomy, preferably with silicone oil endotamponade. Applying an encircling band, retinotomy or retinectomy can be useful in reattaching the tractional shortened retina.
  
  
  CONCLUSIONS
  Surgery is still the method of choice for the treatment of PVR. Pharmacological strategies to prevent or treat PVR have not been established.
authors.affiliation: Zentrum für Augenheilkunde, Universität zu Köln.
authors.forename: F
authors.initials: F
authors.lastname: Schaub
authors.affiliation: Zentrum für Augenheilkunde, Universität zu Köln.
authors.forename: P
authors.initials: P
authors.lastname: Enders
authors.affiliation: Zentrum für Augenheilkunde, Universität zu Köln.
authors.forename: S
authors.initials: S
authors.lastname: Fauser
mesh_terms: D020533:Angiogenesis Inhibitors / Q000008:administration & dosage*; D000893:Anti-Inflammatory Agents / Q000008:administration & dosage*; D003131:Combined Modality Therapy / Q000379:methods; D058450:Endotamponade / Q000379:methods*; D019317:Evidence-Based Medicine; D006801:Humans; D012591:Scleral Buckling / Q000379:methods*; D016896:Treatment Outcome; D014821:Vitrectomy / Q000379:methods*; D057586:Vitreoretinal Surgery / Q000009:adverse effects; D018630:Vitreoretinopathy, Proliferative / Q000175:diagnosis / Q000209:etiology / Q000601:surgery*; D014822:Vitreous Body / Q000601:surgery
chemical_list: D020533:Angiogenesis Inhibitors; D000893:Anti-Inflammatory Agents