title: Phenyl trimethyl ammonium tribromide mediated robust one-pot synthesis of spiro-oxacycles - an economic route - stereoselective synthesis of oxaspirohexacyclodieneones.
abstract: This paper entails the first recognition of Phenyl Trimethyl Ammonium Tribromide (PTAB) as an effective reagent for spiro-cyclizations proceeding via oxidative dearomatization. The experiment exhibits economical, metal and ligand free one-pot accomplishment of these significant transformations. The described protocol presents the first generalised methodology of spiro-oxacycle synthesis which can be applied towards various directions. A stereoselective synthesis of oxa-spirocyclooxadieneones has been accomplished.
authors.affiliation: Organic Synthesis and Molecular Engineering Laboratory, Department of Chemistry, National Institute of Technology, Rourkela, Odisha 769008, India. sarkard@nitrkl.ac.in.
authors.forename: Debayan
authors.initials: D
authors.lastname: Sarkar
authors.affiliation: Organic Synthesis and Molecular Engineering Laboratory, Department of Chemistry, National Institute of Technology, Rourkela, Odisha 769008, India. sarkard@nitrkl.ac.in.
authors.forename: Manoj Kumar
authors.initials: MK
authors.lastname: Ghosh
authors.affiliation: Organic Synthesis and Molecular Engineering Laboratory, Department of Chemistry, National Institute of Technology, Rourkela, Odisha 769008, India. sarkard@nitrkl.ac.in.
authors.forename: Nilendri
authors.initials: N
authors.lastname: Rout