title: Cytogenetics in the management of hematologic malignancies: an update by the Groupe francophone de cytogénétique hématologique (GFCH).
abstract: Cytogenetic analysis is still important in the management of many hematological malignancies, despite the new techniques available such as the high-throughput sequencing analysis, and the discovery of many acquired gene mutations in these diseases. The Groupe francophone de cytogénétique hématologique (GFCH) published in 2004 the recommendations for the cytogenetic management of hematological malignancies. It reports here the update of these recommendations, with a review of the literature for each disease.
authors.affiliation: UPMC Paris 6, Inserm UMRS 1138, Hôpital de la Pitié-Salpêtrière, Paris, France.
authors.forename: Florence
authors.initials: F
authors.lastname: Nguyen-Khac
authors.affiliation: UF de cytogénétique hématologique, Pôle biologie-hygiène, Centre hospitalier de Valenciennes, France.
authors.forename: Agnès
authors.initials: A
authors.lastname: Daudignon
authors.affiliation: Laboratoire d'hématologie et de cytogénétique, Hôpital Avicenne, AP-HP, Bobigny, France.
authors.forename: Virginie
authors.initials: V
authors.lastname: Eclache
authors.affiliation: Laboratoire de cytogénétique onco-hématologique, Hôpital Timone Enfants, Aix-Marseille Université, Marseille, France.
authors.forename: Marina
authors.initials: M
authors.lastname: Lafage-Pochitaloff
authors.affiliation: Unité de cytogénétique onco-hématologique, Institut de biologie et de pathologie, CHU Grenoble, France.
authors.forename: Christine
authors.initials: C
authors.lastname: Lefebvre
authors.affiliation: Laboratoire d'hématologie, Institut universitaire du cancer Toulouse - Oncopole, Toulouse, France.
authors.forename: Isabelle
authors.initials: I
authors.lastname: Luquet
authors.affiliation: Laboratoire de génétique oncologique, Centre Henri Becquerel, Rouen, France.
authors.forename: Dominique
authors.initials: D
authors.lastname: Penther
mesh_terms: D020732:Cytogenetic Analysis / Q000379:methods / Q000592:standards / Q000639:trends; D005602:France; D019337:Hematologic Neoplasms / Q000175:diagnosis* / Q000235:genetics / Q000628:therapy; D006405:Hematology / Q000458:organization & administration / Q000592:standards*; D006801:Humans; D012955:Societies, Medical / Q000592:standards
keywords: cytogenetic abnormalities; hematological malignancies