title: New QSAR Models for Human Cytochromes P450, 1A2, 2D6 and 3A4 Implicated in the Metabolism of Drugs. Relevance of Dataset on Model Development.
authors.affiliation: Univ. Orléans, CNRS, ICOA, UMR 7311, F-45067 Orléans, France.
authors.forename: Juan
authors.initials: J
authors.lastname: Martinez-Sanz
authors.affiliation: Univ. Orléans, CNRS, ICOA, UMR 7311, F-45067 Orléans, France.
authors.forename: Pascal
authors.initials: P
authors.lastname: Bonnet
authors.affiliation: Technologie Servier, 25-27 rue Eugène Vignat, 45000 Orléans, France.
authors.forename: Sylvain
authors.initials: S
authors.lastname: Lozano
authors.affiliation: Technologie Servier, 25-27 rue Eugène Vignat, 45000 Orléans, France.
authors.forename: Alban
authors.initials: A
authors.lastname: Arrault
authors.affiliation: Univ. Orléans, CNRS, ICOA, UMR 7311, F-45067 Orléans, France.
authors.forename: Luc
authors.initials: L
authors.lastname: Morin-Allory
authors.affiliation: Technologie Servier, 25-27 rue Eugène Vignat, 45000 Orléans, France. philippe.vayer@fr.netgrs.com.
authors.forename: Philippe
authors.initials: P
authors.lastname: Vayer
keywords: ADME; CYP450; QSAR model; Random Forest; Support Vector Machine