title: [Research on Life Quality Scale for Patients with Idiopathic Pulmonary Fibrosis].
abstract: OBJECTIVE
  To develop a life quality scale suitable for idiopathic pulmonary fibrosis (IPF) patients, objectively reflecting its changes.
  
  
  METHODS
  Authors first put forward a theoretical structure model of a scale according to patient-reported outcome (PRO) scale formulation principle by combining basic theories of Chinese medicine (CM). Then authors developed an initial scale on the basis of various life quality scales for respiratory disease patients by using structural decision making. Totally 34 patients with confirmed diagnosis of IPF were tested by questionnaire. Items were screened using expert importance scoring method, factor analysis, correlation coefficient method, Cronbach's alpha coefficient method. IPF patient reported outcomes (IPF PRO, IP) were finally defined.
  
  
  RESULTS
  A new IP scale was developed covering three areas and 38 items. Pearson correlation coefficient for correlation analysis of clinical symptom scores in ST-George Respiratory Questionnaire and IP scale was 0.828 (P < 0.01). Pearson correlation coefficient for correlation analysis of activity ability scores was 0.929 (P < 0.01). Pearson correlation coefficient for correlation analysis of total scores was 0.862 (P < 0.01). By reliability of IP scale itself (reliability) analysis, Cronbach's alpha coefficient was 0.713. By using factor analysis method for data analysis, KMO statistics was 0.902.
  
  
  CONCLUSIONS
  IP scale fully reflected the connotation of IPF patients' quality of life, so it could be used as CM clinical therapeutic effect evaluation tool.
authors.forename: Li-juan
authors.initials: LJ
authors.lastname: Liang
authors.forename: Li-rong
authors.initials: LR
authors.lastname: Liang
authors.forename: Hua-ping
authors.initials: HP
authors.lastname: Dai
mesh_terms: D006801:Humans; D054990:Idiopathic Pulmonary Fibrosis / Q000175:diagnosis*; D008516:Medicine, Chinese Traditional; D011788:Quality of Life; D015203:Reproducibility of Results; D012107:Research Design; D011795:Surveys and Questionnaires