title: A TP-FRET-based two-photon fluorescent probe for ratiometric visualization of endogenous sulfur dioxide derivatives in mitochondria of living cells and tissues.
abstract: A ratiometric two-photon fluorescent probe for SO2 derivatives was first proposed based on acedan-merocyanine dyads via a TP-FRET strategy. It was successfully applied to visualization of the fluctuations of enzymatically generated SO2 derivatives in the mitochondria of HepG2 cells and rat liver tissues using two-photon fluorescence microscopy imaging.
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ysh1127@hnu.edu.cn yangrh@pku.edu.cn.
authors.forename: Xiaoguang
authors.initials: X
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Yibo
authors.initials: Y
authors.lastname: Zhou
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Xiufang
authors.initials: X
authors.lastname: Zhang
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ysh1127@hnu.edu.cn yangrh@pku.edu.cn.
authors.forename: Sheng
authors.initials: S
authors.lastname: Yang
authors.affiliation: State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Yun
authors.initials: Y
authors.lastname: Chen
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ysh1127@hnu.edu.cn yangrh@pku.edu.cn.
authors.forename: Jingru
authors.initials: J
authors.lastname: Guo
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ysh1127@hnu.edu.cn yangrh@pku.edu.cn.
authors.forename: Xiaoxuan
authors.initials: X
authors.lastname: Li
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ysh1127@hnu.edu.cn yangrh@pku.edu.cn.
authors.forename: Zhihe
authors.initials: Z
authors.lastname: Qing
authors.affiliation: School of Chemistry and Biological Engineering, Changsha University of Science and Technology, Changsha, 410114, China. ysh1127@hnu.edu.cn yangrh@pku.edu.cn and State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China.
authors.forename: Ronghua
authors.initials: R
authors.lastname: Yang
mesh_terms: D000818:Animals; D002470:Cell Survival; D031541:Fluorescence Resonance Energy Transfer; D005456:Fluorescent Dyes / Q000737:chemistry* / Q000378:metabolism; D056945:Hep G2 Cells; D006801:Humans; D008099:Liver / Q000737:chemistry* / Q000378:metabolism; D008928:Mitochondria / Q000737:chemistry* / Q000378:metabolism; D017785:Photons; D051381:Rats; D013458:Sulfur Dioxide / Q000737:chemistry / Q000378:metabolism*
chemical_list: D005456:Fluorescent Dyes; D013458:Sulfur Dioxide