title: Benign and Malignant Salivary Gland Tumors - Clinical and Demographic Characteristics.
abstract: OBJECTIVE
  To examine the demographic, ethnic, and clinical characteristics of salivary benign and malignant tumors for better etiological understanding.
  
  
  METHODS
  We examined medical records of 287 primary salivary gland tumor patients.
  
  
  RESULTS
  Overall, 216 tumors were benign and 71 malignant. The mean age at diagnosis was 56.4 years for those with malignant tumors and 48.5 years for those with benign, a highly significant difference (p=0.001). Females had 45% of malignant tumors and 59% of benign, a significant difference (p=0.037). Ethnic origin, alcohol consumption and cigarette smoking rates were not significantly different (p>0.05) between groups. A total of 87% of benign and 55% of malignant tumors were in the parotid glands, a highly significant predilection (p<0.0001), sublocated mostly in the superfacial lobe; 36.6% of malignant tumors and 4.7% of benign (p<0.0001) were in the minor salivary glands, mostly in the hard palate.
  
  
  CONCLUSIONS
  Baseline clinical, demographic and locational aspects of benign and malignant tumors are substantiated.
authors.affiliation: Department of Oral and Maxillofacial Surgery, Rambam Medical Center, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel.
authors.forename: Yair
authors.initials: Y
authors.lastname: Israel
authors.affiliation: Department of Oral and Maxillofacial Surgery, Rambam Medical Center, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel.
authors.forename: Adi
authors.initials: A
authors.lastname: Rachmiel
authors.affiliation: Department of Otolaryngology Head and Neck Surgery, Rambam Medical Center, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel.
authors.forename: Gil
authors.initials: G
authors.lastname: Ziv
authors.affiliation: Department of Oral and Maxillofacial Surgery, Rambam Medical Center, Faculty of Medicine, Rappaport Family Institute for Research in the Medical Sciences, Technion - Israel Institute of Technology, Haifa, Israel nagler@tx.technion.ac.il.
authors.forename: Rafael
authors.initials: R
authors.lastname: Nagler
mesh_terms: D008949:Adenoma, Pleomorphic / Q000453:epidemiology* / Q000473:pathology; D003537:Cystadenoma / Q000453:epidemiology* / Q000473:pathology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D012468:Salivary Gland Neoplasms / Q000453:epidemiology* / Q000473:pathology; D047368:Tumor Burden
keywords: Salivary glands; benign carcinoma; clinical characteristics; demographic characteristics; malignant tumor