title: Influenza virus vaccine for neglected hosts: horses and dogs.
abstract: This study provides information regarding vaccine research and the epidemiology of influenza virus in neglected hosts (horses and dogs). Equine influenza virus (EIV) causes a highly contagious disease in horses and other equids, and outbreaks have occurred worldwide. EIV has resulted in costly damage to the horse industry and has the ability of cross the host species barrier from horses to dogs. Canine influenza is a virus of equine or avian origin and infects companion animals that live in close contact with humans; this results in possible exposure to the seasonal epizootic influenza virus. There have been case reports of genetic reassortment between human and canine influenza viruses, which results in high virulence and the ability of transmission to ferrets. This emphasizes the need for vaccine research on neglected hosts to update knowledge on current strains and to advance technology for controlling influenza outbreaks for public health.
authors.affiliation: College of Pharmacy, Korea University, Sejong, Korea.
authors.forename: Woonsung
authors.identifier: 0000-0002-7254-5240
authors.initials: W
authors.lastname: Na
authors.affiliation: College of Pharmacy, Korea University, Sejong, Korea.
authors.forename: Minjoo
authors.identifier: 0000-0001-8949-6361
authors.initials: M
authors.lastname: Yeom
authors.affiliation: College of Pharmacy, Korea University, Sejong, Korea.
authors.forename: Huijoon
authors.identifier: 0000-0002-9076-0155
authors.initials: H
authors.lastname: Yuk
authors.affiliation: Research Unit, Green Cross Veterinary Products, Yongin, Korea.
authors.forename: Hyoungjoon
authors.identifier: 0000-0001-6211-8758
authors.initials: H
authors.lastname: Moon
authors.affiliation: Research Unit, Green Cross Veterinary Products, Yongin, Korea.
authors.forename: Bokyu
authors.identifier: 0000-0001-5840-468X
authors.initials: B
authors.lastname: Kang
authors.affiliation: College of Pharmacy, Korea University, Sejong, Korea.
authors.forename: Daesub
authors.identifier: 0000-0002-2759-1061
authors.initials: D
authors.lastname: Song
keywords: Disease transmission; H3N2 subtype; H3N8 subtype; Infectious; Influenza A virus; Influenza vaccine