title: Connecting chromosome replication with cell growth in bacteria.
abstract: For bacteria to proliferate they must duplicate their genetic material so that it can be passed to their progeny. This requires that DNA replication is coordinated with cell growth and division. In the natural environment bacterial growth is dynamic and strongly influenced by changes in nutrient availability. Recent studies have found that bacteria utilize a range of regulatory systems, many of them species-specific, to coordinate DNA replication with cell growth. This variability likely reflects the diverse lifestyles of different bacterial types.
authors.affiliation: Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle Upon Tyne NE2 4AX, UK. Electronic address: heath.murray@newcastle.ac.uk.
authors.forename: Heath
authors.initials: H
authors.lastname: Murray
mesh_terms: D001419:Bacteria / Q000235:genetics* / Q000254:growth & development*; D002453:Cell Cycle / Q000235:genetics; D002455:Cell Division; D002876:Chromosomes, Bacterial / Q000378:metabolism*; D000458:Cyanobacteria / Q000235:genetics / Q000254:growth & development; D004261:DNA Replication / Q000235:genetics*; D004269:DNA, Bacterial / Q000378:metabolism; D004268:DNA-Binding Proteins / Q000235:genetics / Q000378:metabolism
chemical_list: D004269:DNA, Bacterial; D004268:DNA-Binding Proteins