title: Effects of dietary green tea polyphenol supplementation on the health of workers exposed to high-voltage power lines.
abstract: Although it has been several decades since the focus on the effect of extremely low frequency electromagnetic fields (ELF-EMF) of high-voltage power lines on human health, no consistent conclusion has been drawn. The present study aimed to investigate the change in oxidative stress after exposure to ELF-EMFs, and potential protective effects of green tea polyphenol supplementation (GTPS) on ELF-EMFs induced oxidative stress. A total of 867 subjects, including workers with or without exposure to ELF-EMFs of 110-420kV power lines, participated and were randomized into GTPS and placebo treatment groups. Oxidative stress and oxidative damage to DNA were assessed by urinary tests of 8-isoprostane and 8-OHdG. Significant increased urinary 8-isoprostane and 8-OHdG were observed in workers with ELF-EMFs exposure, which were diminished after 12 months of GTPS. No protective effects of GTPS on oxidative stress and oxidative damage to DNA were observed after three months of GTPS withdraw. We found a negative impact of high-voltage power lines on the health of workers. Long-term GTPS could be an efficient protection against the health issues induced by high-voltage power lines.
authors.affiliation: Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
authors.forename: Yang
authors.initials: Y
authors.lastname: Zhang
authors.affiliation: Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
authors.forename: Dan
authors.initials: D
authors.lastname: Zhang
authors.affiliation: Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
authors.forename: Baoyu
authors.initials: B
authors.lastname: Zhu
authors.affiliation: Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
authors.forename: He
authors.initials: H
authors.lastname: Zhang
authors.affiliation: Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China.
authors.forename: Ye
authors.initials: Y
authors.lastname: Sun
authors.affiliation: Electrical Power Research Institute, Jilin Electrical Power Company Limited, Changchun 130021, China. Electronic address: sunchengxun1614@sohu.com.
authors.forename: Chengxun
authors.initials: C
authors.lastname: Sun
mesh_terms: D000328:Adult; D028241:Camellia sinensis / Q000737:chemistry*; D019587:Dietary Supplements; D015237:Dinoprost / Q000031:analogs & derivatives / Q000652:urine; D004559:Electric Wiring; D004574:Electromagnetic Fields / Q000009:adverse effects*; D006801:Humans; D008297:Male; D008875:Middle Aged; D016273:Occupational Exposure / Q000009:adverse effects*; D018384:Oxidative Stress / Q000187:drug effects*; D059808:Polyphenols / Q000008:administration & dosage / Q000494:pharmacology*; D011795:Surveys and Questionnaires
chemical_list: D059808:Polyphenols; C075750:8-epi-prostaglandin F2alpha; D015237:Dinoprost
keywords: Extremely low frequency electromagnetic fields (ELF-EMF); Green tea polyphenol supplementation (GTPS); High-voltage power lines; Oxidative stress