title: Red light activated "caged" reagents for microRNA research.
abstract: "Caged" reagents for miRNA research (siRNA targeting EGFR, involved in miRNA maturation, and mimics of miR-20a, playing a key role in tumor formation and metastasis) were prepared. It was demonstrated that these reagents can be activated by non-toxic to cells red light both in cells and in cell free settings.
authors.affiliation: Friedrich-Alexander-University of Erlangen-Nürnberg, Department of Chemistry and Pharmacy, Organic Chemistry II, Henkestr. 42, 91054 Erlangen, Germany. Andriy.Mokhir@fau.de.
authors.forename: A
authors.initials: A
authors.lastname: Meyer
authors.affiliation: Friedrich-Alexander-University of Erlangen-Nürnberg, Department of Chemistry and Pharmacy, Organic Chemistry II, Henkestr. 42, 91054 Erlangen, Germany. Andriy.Mokhir@fau.de.
authors.forename: M
authors.initials: M
authors.lastname: Schikora
authors.affiliation: Ruprecht-Karls-University of Heidelberg, BIOQUANT, Im Neuenheimer Feld 267, 69120 Heidelberg, Germany and Faculty of Natural Sciences, University of Vilnius, Vilnius, Lithuania.
authors.forename: V
authors.initials: V
authors.lastname: Starkuviene
authors.affiliation: Friedrich-Alexander-University of Erlangen-Nürnberg, Department of Chemistry and Pharmacy, Organic Chemistry II, Henkestr. 42, 91054 Erlangen, Germany. Andriy.Mokhir@fau.de.
authors.forename: A
authors.initials: A
authors.lastname: Mokhir
mesh_terms: D006801:Humans; D008027:Light; D035683:MicroRNAs / Q000037:antagonists & inhibitors* / Q000235:genetics / Q000378:metabolism; D009369:Neoplasms / Q000188:drug therapy* / Q000235:genetics / Q000378:metabolism; D034741:RNA, Small Interfering / Q000737:chemistry / Q000494:pharmacology*
chemical_list: D035683:MicroRNAs; D034741:RNA, Small Interfering