title: CLINICAL MANAGEMENT OF BILATERAL CUTANEOUS SQUAMOUS CELL CARCINOMA OF THE HIND FEET PADS IN A SOUTHERN WHITE RHINOCEROS (CERATOTHERIUM SIMUM SIMUM).
abstract: The current report describes the temporary regression, due to intensive symptomatic treatment, of ulcerative skin lesions caused by squamous cell carcinoma in a white rhinoceros. A captive, 40-yr-old southern white rhinoceros (Ceratotherium simum simum) developed profound, ulcerative skin lesions on the pads of both hind feet. At the peak of the disease, at least one quarter of the pads was affected. A diagnosis of squamous cell carcinoma was made via biopsy. Treatment included anti-inflammatory drugs, antibiotics, and local care. The lesions regressed on both feet until they seemed clinically healed. It was presumed that long-term, anti-inflammatory treatment and local bandaging had induced the temporary regression of the lesions. Two years later, however, a small ulcerative lesion reappeared on one pad and post mortem examination confirmed that the carcinoma was also histologically present in the clinically intact tissue. No metastasis was found and computed tomography showed normal digital bones.
authors.forename: Eva Maria
authors.initials: EM
authors.lastname: Greunz
authors.forename: Marie
authors.initials: M
authors.lastname: Simon
authors.forename: Karin
authors.initials: K
authors.lastname: Lemberger
authors.forename: Gabriela
authors.initials: G
authors.lastname: Galateanu
authors.forename: Robert
authors.initials: R
authors.lastname: Hermes
authors.forename: Antoine
authors.initials: A
authors.lastname: Leclerc
mesh_terms: D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D000894:Anti-Inflammatory Agents, Non-Steroidal / Q000627:therapeutic use; D001458:Bandages; D019817:Benzoic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D002294:Carcinoma, Squamous Cell / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D002710:Chlorhexidine / Q000008:administration & dosage / Q000627:therapeutic use; D005260:Female; D005534:Foot Diseases / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*; D008293:Malates / Q000008:administration & dosage / Q000627:therapeutic use; D010527:Perissodactyla; D010653:Phenylbutazone / Q000627:therapeutic use; D020156:Salicylic Acid / Q000008:administration & dosage / Q000627:therapeutic use; D012878:Skin Neoplasms / Q000175:diagnosis / Q000628:therapy / Q000662:veterinary*
chemical_list: D000900:Anti-Bacterial Agents; D000894:Anti-Inflammatory Agents, Non-Steroidal; D008293:Malates; C030298:malic acid; D019817:Benzoic Acid; D010653:Phenylbutazone; D020156:Salicylic Acid; D002710:Chlorhexidine
keywords: Ceratotherium simum simum; foot pad; imaging diagnosis; regression; squamous cell carcinoma; white rhinoceros