title: Syndrome of inappropriate secretion of antidiuretic hormone (SIADH) associated with lateral medullary syndrome: case report and literature review.
abstract: BACKGROUND
  Only one case of syndrome of inappropriate secretion of antidiuretic hormone with lateral medullary syndrome has been reported so far. We report a case of lateral medullary syndrome showing syndrome of inappropriate secretion of antidiuretic hormone and analyze the pathomechanism underlying its clinical features.
  
  
  METHODS
  A 67-year-old man was admitted to our hospital for dizziness, dysarthria, and dysphagia. He was diagnosed with lateral medullary syndrome based on the neurological examination and brain magnetic resonance imaging. Horner syndrome was absent. Asymptomatic hyponatremia appeared 9 days after admission and the patient was diagnosed with syndrome of inappropriate secretion of antidiuretic hormone. Fluid restriction and intravenous furosemide injection improved the hyponatremia.
  
  
  CONCLUSIONS
  Lateral medullary syndrome could be associated with syndrome of inappropriate secretion of antidiuretic hormone.
authors.affiliation: Department of Neurology, Kouseiren Takaoka Hospital, Takaoka, Japan. neuro-nakano@med.kanazawa-u.ac.jp.|Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan. neuro-nakano@med.kanazawa-u.ac.jp.
authors.forename: Hiroro
authors.identifier: http://orcid.org/0000-0002-3958-7019
authors.initials: H
authors.lastname: Nakano
authors.affiliation: Department of Neurology, Kouseiren Takaoka Hospital, Takaoka, Japan.
authors.forename: Daisuke
authors.initials: D
authors.lastname: Yanase
authors.affiliation: Department of Neurology and Neurobiology of Aging, Kanazawa University Graduate School of Medical Sciences, 13-1 Takara-machi, Kanazawa, 920-8640, Japan.
authors.forename: Masahito
authors.initials: M
authors.lastname: Yamada
mesh_terms: D000368:Aged; D000983:Antipyrine / Q000031:analogs & derivatives / Q000627:therapeutic use; D001120:Arginine / Q000031:analogs & derivatives; D000077144:Clopidogrel; D038524:Diffusion Magnetic Resonance Imaging / Q000379:methods; D004232:Diuretics / Q000627:therapeutic use; D000077553:Edaravone; D016166:Free Radical Scavengers / Q000627:therapeutic use; D005665:Furosemide / Q000627:therapeutic use; D006801:Humans; D007010:Hyponatremia / Q000188:drug therapy / Q000209:etiology; D007177:Inappropriate ADH Syndrome / Q000188:drug therapy / Q000209:etiology*; D014854:Lateral Medullary Syndrome / Q000150:complications* / Q000000981:diagnostic imaging; D008297:Male; D010875:Pipecolic Acids / Q000627:therapeutic use; D010975:Platelet Aggregation Inhibitors / Q000627:therapeutic use; D013449:Sulfonamides; D013988:Ticlopidine / Q000031:analogs & derivatives / Q000627:therapeutic use
chemical_list: D004232:Diuretics; D016166:Free Radical Scavengers; D010875:Pipecolic Acids; D010975:Platelet Aggregation Inhibitors; D013449:Sulfonamides; D005665:Furosemide; D001120:Arginine; D000077144:Clopidogrel; C031942:argatroban; D013988:Ticlopidine; D000077553:Edaravone; D000983:Antipyrine
keywords: Antidiuretic hormone; Lateral medullary syndrome; Syndrome of inappropriate secretion of antidiuretic hormone; The nucleus of the solitary tract; The paraventricular nucleus in the hypothalamus