title: Focus on optimization of early antimicrobial therapy in ICU-acquired infections.
authors: Université Paris Diderot/Hôpital Bichat, Réanimation Médicale et des maladies infectieuses, 46 rue Henri Huchard, 75018, Paris, France. Jean-francois.timsit@bch.aphp.fr.|U1137-IAME Team 5, DeSCID: Decision SCiences in Infectious Diseases, Control and Care, Inserm/Université Paris Diderot, Sorbonne Paris Cité, 75018, Paris, France. Jean-francois.timsit@bch.aphp.fr.
authors: Jean-François
authors: JF
authors: Timsit
authors: Department of Emergency and Intensive Care, Centro Hospitalar Sao Joao, Porto, Portugal.|Department of Medicine, Faculty of Medicine, University of Porto, Porto, Portugal.
authors: José-Artur
authors: JA
authors: Paiva
authors: Clinica Malattie Infettive, Azienda Ospedaliera Universitaria Santa Maria della Misericorida, Udine, Italy.|University of Udine School of Medicine, Udine, Italy.
authors: Matteo
authors: M
authors: Bassetti
mesh_terms: D000890:Anti-Infective Agents / Q000627:therapeutic use*; D003428:Cross Infection / Q000188:drug therapy* / Q000382:microbiology / Q000635:transmission; D024881:Drug Resistance, Bacterial; D006801:Humans; D007362:Intensive Care Units; D055624:Methicillin-Resistant Staphylococcus aureus / Q000187:drug effects; D010359:Patient Readmission; D055502:Secondary Prevention / Q000379:methods*
chemical_list: D000890:Anti-Infective Agents