title: MODEM: multi-omics data envelopment and mining in maize.
abstract: MODEM is a comprehensive database of maize multidimensional omics data, including genomic, transcriptomic, metabolic and phenotypic information from the cellular to individual plant level. This initial release contains approximately 1.06 M high quality SNPs for 508 diverse inbred lines obtained by combining variations from RNA sequencing on whole kernels (15 days after pollination) of 368 lines and a 50 K array for all 508 individuals. As all of these data were derived from the same diverse panel of lines, the database also allows various types of genetic mapping (including characterization of phenotypic QTLs, pQTLs; expression QTLs, eQTLs and metabolic QTLs, mQTLs). MODEM is thus designed to promote a better understanding of maize genetic architecture and deep functional annotation of the complex maize genome (and potentially those of other crop plants) and to explore the genotype-phenotype relationships and regulation of maize kernel development at multiple scales, which is also comprehensive for developing novel methods. MODEM is additionally designed to link with other databases to make full use of current resources, and it provides visualization tools for easy browsing. All of the original data and the related mapping results are freely available for easy query and download. This platform also provides helpful tools for general analyses and will be continually updated with additional materials, features and public data related to maize genetics or regulation as they become available.Database URL: (http://modem.hzau.edu.cn).
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Haijun
authors: H
authors: Liu
authors: College of Informatics, Huazhong Agricultural University, Wuhan 430070, China.
authors: Fan
authors: F
authors: Wang
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Yingjie
authors: Y
authors: Xiao
authors: College of Informatics, Huazhong Agricultural University, Wuhan 430070, China.
authors: Zonglin
authors: Z
authors: Tian
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Weiwei
authors: W
authors: Wen
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Xuehai
authors: X
authors: Zhang
authors: School of Mechanical Engineering, Shandong University, Jinan 250061, China.
authors: Xi
authors: X
authors: Chen
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Nannan
authors: N
authors: Liu
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Wenqiang
authors: W
authors: Li
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Lei
authors: L
authors: Liu
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Jie
authors: J
authors: Liu
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China.
authors: Jianbing
authors: J
authors: Yan
authors: National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, China College of Informatics, Huazhong Agricultural University, Wuhan 430070, China School of Computer & software, Nanjing University of Information Science & Technology, Nanjing 210000, China liujianxiao@mail.hzau.edu.cn.
authors: Jianxiao
authors: J
authors: Liu
mesh_terms: D030561:Databases, Nucleic Acid; D017343:Genes, Plant; D023281:Genomics; D005838:Genotype; D010641:Phenotype; D020641:Polymorphism, Single Nucleotide; D003313:Zea mays / Q000235:genetics / Q000378:metabolism