title: 23 Lung Metastases Treated by Radiofrequency Ablation Over 10 Years in a Single Patient: Successful Oncological Outcome of a Metastatic Cancer Without Altered Respiratory Function.
abstract: An 82-year-old man, who was diagnosed in 2002 with an oncocytic (Hürthle cell) thyroid carcinoma, was initially treated by local surgery and was refractory to radioiodine treatment. The patient had successive secondary recurrences from 2006 onwards. Metastases were suspected due to an elevation of thyroglobulin in serum. Hypermetabolic nodules were targeted using FDG PET as well as CT-guided radiofrequency ablations. Thyroglobulin levels decreased following each procedure. 10 years later, tolerance and efficacy are excellent; 23 lung metastases have been treated during 11 sessions without current relapse. Respiratory function and quality of life are not altered. This report illustrates how radiofrequency ablation can be efficiently integrated into the long-term management of poorly aggressive oligometastatic cancer, in combination with other local and/or systemic therapies.
authors: Department of Radiology, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux Cedex, France. amandine.crombe@ens-lyon.fr.
authors: Amandine
authors: A
authors: Crombé
authors: Department of Radiology, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux Cedex, France.
authors: Xavier
authors: X
authors: Buy
authors: Department of Nuclear Medicine, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux Cedex, France.
authors: Yann
authors: Y
authors: Godbert
authors: Department of Radiology, Centre Hospitalier Alpes-Léman, 74130, Contamine Sur Arve, France.
authors: Nicolas
authors: N
authors: Alberti
authors: Department of Radiology, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux Cedex, France.
authors: Michèle
authors: M
authors: Kind
authors: Department of Nuclear Medicine, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux Cedex, France.
authors: Françoise
authors: F
authors: Bonichon
authors: Department of Radiology, Institut Bergonié, 229 cours de l'Argonne, 33076, Bordeaux Cedex, France.
authors: Jean
authors: J
authors: Palussière
mesh_terms: D000369:Aged, 80 and over; D017115:Catheter Ablation / Q000379:methods*; D006801:Humans; D008168:Lung / Q000502:physiology* / Q000601:surgery; D008175:Lung Neoplasms / Q000556:secondary* / Q000601:surgery*; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000601:surgery*; D012129:Respiratory Function Tests; D013964:Thyroid Neoplasms / Q000473:pathology*
keywords: Hürthle-cell carcinoma; Long-term follow-up; Lung metastases; Radiofrequency ablation