title: Should prophylactic measures to prevent postpolypectomy bleeding after resection of large colorectal polyps be used?
abstract: Post-polypectomy bleeding after colonoscopy with resection of large colorectal polyps can cause significant morbidity (readmission for monitoring, transfusion, repeat endoscopy and therapy) and a significant cost to hospitals and insurers. Nevertheless prophylactic endoscopic measures could reduce risk of post-polypectomy bleeding. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified two systematic reviews including 10 randomized trials. We combined the evidence using meta-analysis and generated a summary of findings table following the GRADE approach. We concluded prophylactic endoscopic measures could be effective in reducing post-polypectomy bleeding after resection of large colorectal polyps.
authors: Servicios de Gastroenterología y Endoscopía Digestiva, Hospital Alemán, Buenos Aires, Argentina; Programa de Medicina Basada en Pruebas, Hospital Alemán, Buenos Aires, Argentina Address: Hospital Alemán de Buenos Aires, Av. Pueyrredon 1640, CP C118AAT, +54114827700. Email: ariel.izcovich@gmail.com.
authors: Estanislao J
authors: EJ
authors: Gómez
authors: Servicios de Gastroenterología y Endoscopía Digestiva, Hospital Alemán, Buenos Aires, Argentina; Programa de Medicina basada en pruebas, Hospital Alemán, Buenos Aires, Argentina.
authors: Ariel
authors: A
authors: Izcovich
mesh_terms: D003111:Colonic Polyps / Q000601:surgery*; D003113:Colonoscopy / Q000379:methods*; D004724:Endoscopy / Q000379:methods; D006471:Gastrointestinal Hemorrhage / Q000209:etiology / Q000517:prevention & control*; D006801:Humans; D016032:Randomized Controlled Trials as Topic