title: Effect of Statins on the Mortality of Bacteremic Patients: A Systematic Review and Meta-analysis of Clinical Trials.
abstract: BACKGROUND
  Statins modify inflammatory cell signaling during the immune response to infection. This has been considered as a pleotropic effect. Effects of statins in inflammatory conditions such as bacteremia have been found to be controversial.
  
  
  OBJECTIVE
  We examined the effect of statins on the mortality of bacteremia patients.
  
  
  METHODS
  Major databases were searched for the pertinent clinical trials.
  
  
  RESULTS
  Six cohort studies comprising 7553 patients were included. Hospital mortality was lower (15.36% vs 22.28%) in patients on statin.
  
  
  CONCLUSIONS
  There may be a potential role of statins in similar inflammatory and infective conditions.
authors: Department of Internal Medicine, Nanjing Medical University, Nanjing, Jiangsu, China.
authors: Pragya
authors: P
authors: Shrestha
authors: Department of Internal Medicine, Reading Health System, West Reading, Pennsylvania, USA.
authors: Dilli R
authors: DR
authors: Poudel
authors: Department of Internal Medicine, Reading Health System, West Reading, Pennsylvania, USA.
authors: Ranjan
authors: R
authors: Pathak
authors: Department of Internal Medicine, Reading Health System, West Reading, Pennsylvania, USA.
authors: Sushil
authors: S
authors: Ghimire
authors: Department of Internal Medicine, Universal College of Medical Sciences, Bhairahawa, Nepal.
authors: Rashmi
authors: R
authors: Dhital
authors: Department of Internal Medicine, Reading Health System, West Reading, Pennsylvania, USA.
authors: Madan R
authors: MR
authors: Aryal
authors: Department of Internal Medicine, Reading Health System, West Reading, Pennsylvania, USA.
authors: Maryam
authors: M
authors: Mahmood
authors: Department of Internal Medicine, Reading Health System, West Reading, Pennsylvania, USA.
authors: Paras
authors: P
authors: Karmacharya
keywords: Bacteremia; infection; inflammation; mortality