title: Sarcopenic Obesity: An Appraisal of the Current Status of Knowledge and Management in Elderly People.
abstract: Today's increased life expectancy highlights both age-related changes in body composition and a higher prevalence of obesity. Sarcopenic obesity (SO) is assuming a prominent role in cardio-metabolic risk because of the double metabolic burden derived from low muscle mass (sarcopenia) and excess adiposity (obesity). This review evaluates the related studies that have been published over the past 10 years in order to give an updated overview of this new syndrome. There is no consensus on the definition of SO due to the wide heterogeneity of diagnostic criteria and choice of body composition components needed to assess this phenotype. There is a growing body of evidence that the ethio-pathogenesis of SO is complex and multi-factorial, as the consequences are a combination of the outcomes of both sarcopenia and obesity, where the effects are maximised. In order to manage SO, it is important to make lifestyle changes that incorporate weight loss, physical exercise and protein supplementation.
authors: Dr. Manuela Verri, Dipartimento di Biologia e Biotecnologie "Lazzaro Spallanzani", Università degli Studi di Pavia, Via Ferrata 9, 27100 Pavia, Italy, Tel.: +39-0382-986423, fax: +39-0382-986385, e-mail: manuela.verri@unipv.it.
authors: S
authors: S
authors: Molino
authors: M
authors: M
authors: Dossena
authors: D
authors: D
authors: Buonocore
authors: M
authors: M
authors: Verri
mesh_terms: D050154:Adiposity / Q000502:physiology; D000368:Aged; D000375:Aging / Q000502:physiology*; D001823:Body Composition / Q000502:physiology; D004044:Dietary Proteins / Q000008:administration & dosage; D015444:Exercise / Q000502:physiology; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D009765:Obesity / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D011379:Prognosis; D055948:Sarcopenia / Q000150:complications* / Q000503:physiopathology / Q000628:therapy*; D015431:Weight Loss
chemical_list: D004044:Dietary Proteins