title: Xanthogranulomatous endometritis presenting as pyometra and mimicking carcinoma on imaging.
abstract: Xanthogranulomatous endometritis (XGE) is an uncommon but well-established histopathological entity seen affecting the kidney and gallbladder. Involvement of the endometrium is very rare, with only a few case reports in world literature till date. Histologically, it is characterized by the replacement of the endometrium by sheets of foamy histiocytes, plasma cells, lymphocytes, giant cells, and siderophages. We present a case of a 74-year-old female who presented with foul-smelling discharge and postmenopausal bleeding of a short duration. Clinical examination and imaging studies revealed a pyometra, cervical stenosis. A suspicion of carcinoma was raised. Since XGE may mimic an endometrial carcinoma clinically and pathologically, knowledge of this unusual and rare inflammatory pathology is important for both the gynecologists and the pathologists.
authors: Department of Pathology, Army College of Medical Sciences and Base Hospital, Delhi Cantt., New Delhi, India.
authors: Col Ajay
authors: CA
authors: Malik
authors: Department of Pathology, Army College of Medical Sciences and Base Hospital, Delhi Cantt., New Delhi, India.
authors: Sharmila
authors: S
authors: Dudani
authors: Department of Pathology, Army College of Medical Sciences and Base Hospital, Delhi Cantt., New Delhi, India.
authors: Brig N S
authors: BN
authors: Mani
keywords: Endometritis; histopathology; immunohistochemistry