title: Components of the metabolic syndrome and depressive symptoms in community-dwelling older people: the Bambuí Cohort Aging Study.
abstract: OBJECTIVE
  To investigate the moderating effect of an increasing number of clustered metabolic syndrome (MetS) components on the association between MetS and depressive symptoms in a population-based cohort of older adults in Brazil.
  
  
  METHODS
  This analysis used data from the Bambuí Cohort Aging Study. Participants in this cross-sectional study comprised 1,469 community-dwelling older people aged ≥ 60 years. Analyses were performed to assess both the association between depressive symptoms and each individual MetS component and the association between depressive symptoms and clustering of an increasing number of MetS components.
  
  
  RESULTS
  High triglyceride level was the individual component that showed the strongest association with depressive symptoms (odds ratio [OR]: 1.47; 95% confidence intervals [95%CI] 1.19-1.81; p < 0.0001). Only the presence of three MetS components was associated with depressive symptoms (OR = 1.53; 95%CI 1.05-2.23; p = 0.025). No graded association was detected between increasing number of clustered MetS components and depressive symptoms.
  
  
  CONCLUSIONS
  Increasing the number of MetS components did not impact the association with depressive symptoms. The association between high triglyceride level and depressive symptoms highlights the relevance of lipid metabolism abnormalities for the emergence of depressive symptoms in older adults.
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
authors: Luiz Gustavo
authors: LG
authors: Ruas
authors: Department of Psychiatry and Behavioral Sciences and Consortium on Aging, The University of Texas Health Science Center at Houston, Houston, TX, USA.
authors: Breno S
authors: BS
authors: Diniz
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
authors: Josélia O
authors: JO
authors: Firmo
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
authors: Sérgio V
authors: SV
authors: Peixoto
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
authors: Juliana V
authors: JV
authors: Mambrini
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.|Faculdade de Enfermagem, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG, Brazil.
authors: Antônio Ignácio de
authors: AI
authors: Loyola-Filho
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.|Faculdade de Medicina, UFMG, Belo Horizonte, MG, Brazil.
authors: Maria Fernanda
authors: MF
authors: Lima-Costa
authors: Centro de Pesquisas René Rachou, Fundação Oswaldo Cruz, Belo Horizonte, MG, Brazil.
authors: Érico
authors: É
authors: Castro-Costa
mesh_terms: D000368:Aged; D000704:Analysis of Variance; D001938:Brazil; D016000:Cluster Analysis; D003072:Cognition Disorders / Q000503:physiopathology; D003430:Cross-Sectional Studies; D003863:Depression / Q000150:complications / Q000503:physiopathology*; D005260:Female; D006801:Humans; D008019:Life Style; D008297:Male; D024821:Metabolic Syndrome / Q000150:complications / Q000503:physiopathology*; D008875:Middle Aged; D011446:Prospective Studies; D011569:Psychiatric Status Rating Scales; D011619:Psychotropic Drugs / Q000627:therapeutic use; D012307:Risk Factors; D055105:Waist Circumference
chemical_list: D011619:Psychotropic Drugs