title: Esophageal Perforation in a Patient With Kidney Transplantation.
abstract: Esophageal perforation is a rupture of the esophageal wall, caused by iatrogenesis in 56% of cases. Perforation of the esophagus remains a challenge, and its incidence has increased as the use of endoscopic procedures has become more frequent. We report a 54-year-old woman with esophageal perforation 8 days after kidney transplantation. She had received a gastrointestinal consultation prior to her transplantation. This report highlights the fact that perforation may occur after any organ transplantation, especially during the initial 2 weeks after transplantation, when mycophenolate mofetil and cyclosporine as well as and high doses of corticosteroid are administered. If there is a delay in passage and a swallowing difficulty, high doses of immunosuppressive drugs are likely to cause ulceration and perforation. Preventive strategies including intravenous steroids for the first 2 to 3 weeks and divided doses of pills should be considered for such patients.
authors: Manouchehr
authors: M
authors: Amini
authors: Department of Surgery, Research Center for Improvement of Surgical Outcomes and Procedures, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran. al-ghorbani@sina.tums.ac.ir.
authors: Ali
authors: A
authors: Ghorbani Abdehgah
authors: Behnam
authors: B
authors: Molavi
authors: Amir Reza
authors: AR
authors: Radmard
authors: Ali
authors: A
authors: Ali Askari
mesh_terms: D016572:Cyclosporine / Q000627:therapeutic use; D004939:Esophageal Perforation / Q000000981:diagnostic imaging* / Q000601:surgery*; D005260:Female; D006801:Humans; D016030:Kidney Transplantation / Q000009:adverse effects*; D008875:Middle Aged; D009173:Mycophenolic Acid / Q000627:therapeutic use; D011183:Postoperative Complications / Q000601:surgery*; D013256:Steroids; D014057:Tomography, X-Ray Computed
chemical_list: D013256:Steroids; D016572:Cyclosporine; D009173:Mycophenolic Acid