title: Coexistence of preeclampsia and inherited thrombophilia in Turkish pregnant women.
abstract: OBJECTIVE
  To examine the relationship of inherited thrombophilia and other thrombotic risk factors with preeclampsia (PE) in a population of pregnant Turkish women.
  
  
  METHODS
  This was a case cross-sectional study in which 70 women with PE and 60 normal pregnant women were studied to find out the frequency of women with risk factors including inherited thrombophilia among preeclamptic cases.
  
  
  RESULTS
  Hemoglobin, platelet count, uric acid, vitamin B12, folic acid, copper, homocysteine, plasminogen activator inhibitor-1, fibrinogen, protein S, protein C, activated protein C resistance values show significant differences in women with PE in comparison to women with normal pregnancy.
  
  
  CONCLUSIONS
  There may be a link between inherited thrombophilia and PE, at least in a sample of Turkish pregnant women. We also propose that the association between thrombophilia and PE is stronger than suggested previously. Furthermore, copper is selectively elevated in women with PE as an independent marker.
authors: Anatolia Women and IVF Health Center, Ankara, Turkey.
authors: Mehtap
authors: M
authors: Polat
authors: Dr. Zekai Tahir Burak Women Health Care, Education and Research Hospital, High Risk Pregnancy Unit, Ankara, Turkey.
authors: Ebru Hacer
authors: EH
authors: Biberoğlu
authors: Department of Obstetrics and Gynecology, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: İsmail
authors: İ
authors: Güler
authors: Department of Obstetrics and Gynecology, Gynecological Endocrinology Unit, Faculty of Medicine, Gazi University, Ankara, Turkey.
authors: Ömer Kutay
authors: ÖK
authors: Biberoğlu
mesh_terms: D003430:Cross-Sectional Studies; D005260:Female; D005492:Folic Acid; D006801:Humans; D011225:Pre-Eclampsia; D011247:Pregnancy; D019851:Thrombophilia; D014805:Vitamin B 12
chemical_list: D005492:Folic Acid; D014805:Vitamin B 12
keywords: Copper; activated protein C resistance; homocysteine; plasminogen activator inhibitor-1; protein S