title: Profile and Trends of Rotavirus Gastroenteritis in Under 5 children in India, 2012 - 2014, Preliminary Report of the Indian National Rotavirus Surveillance Network.
abstract: OBJECTIVE
  To estimate the burden of rotavirus-associated gastroenteritis in India.
  
  
  METHODS
  Hospital based surveillance network was established, with clinical evaluation and laboratory testing for rotavirus among children aged below 5 years hospitalized with acute gastroenteritis.
  
  
  RESULTS
  Between September 2012 and December 2014, stool samples from 10207 children were tested and rotavirus was detected in 39.6% of cases. Infections were more commonly seen among younger children (<2 years). Detection rates were higher during cooler months of September February. Among rotavirus infected children, 64.0% had severe or very severe disease. G1P[8] was the predominant rotavirus genotype (62.7%) observed during the surveillance period.
  
  
  CONCLUSIONS
  Surveillance data highlights the high rotavirus disease burden and emphasizes the need for close monitoring to reduce morbidity and mortality associated with rotavirus gastroenteritis in India.
authors: National Institute of Epidemiology, Chennai; *Christian Medical College and Hospital, Vellore; and #Indian Council of Medical Research, New Delhi; India Correspondence to: Dr CP Girish Kumar, National Institute of pidemiology, II Main Road, TNHB, Ayapakkam, Chennai 600 077, India. girishkumar@nie.gov.in.
authors: C P Girish
authors: CP
authors: Kumar
authors: S
authors: S
authors: Venkatasubramanian
authors: Gagandeep
authors: G
authors: Kang
authors: Rashmi
authors: R
authors: Arora
authors: Sanjay
authors: S
authors: Mehendale
mesh_terms: D002675:Child, Preschool; D003967:Diarrhea / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D005243:Feces / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology; D006760:Hospitalization / Q000706:statistics & numerical data; D006801:Humans; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015995:Prevalence; D062486:Public Health Surveillance; D012401:Rotavirus / Q000235:genetics; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000503:physiopathology / Q000821:virology