title: Paraneoplastic syndrome demonstrated on99mTc-HMDP bone scan.
abstract: A 23-year-old man, with no relevant medical history, presented with inflammatory peripheral and axial polyarthritis, wrist pain, and persistent low-grade fever for the past 4 months. A bone scintigraphy showed intense periosteal early and delayed uptake in long bones, with normal uptake in the spine, pelvis, and rib cage, and no clear focus of hypermetabolism. CT scan revealed a mediastinal mass. A biopsy of the mass demonstrated Hodgkin lymphoma with bulky disease. This paraneoplastic syndrome as the first sign of intrathoracic Hodgkin's disease is rare.
authors: Service de Médecine Nucléaire, Hospices Civils de Lyon, Lyon, France.|Lyon Neuroscience Research Center, INSERM, CNRS, Université Claude Bernard Lyon 1, Lyon, France.
authors: Sophie
authors: S
authors: Lancelot
authors: Service de Médecine Nucléaire, Hospices Civils de Lyon, Lyon, France. francesco.giammarile@chu-lyon.fr.|Equipe Mixte de Recherche, Université Claude Bernard Lyon 1, 3738, Lyon, France. francesco.giammarile@chu-lyon.fr.|Médecine Nucléaire Groupement Hospitalier Est, 59, boulevard Pinel, 69677, Bron Cedex, France. francesco.giammarile@chu-lyon.fr.
authors: Francesco
authors: http://orcid.org/0000-0002-0550-7893
authors: F
authors: Giammarile
authors: Service de Médecine Nucléaire, Hospices Civils de Lyon, Lyon, France.
authors: Agnes
authors: A
authors: Tescaru
mesh_terms: D001859:Bone Neoplasms / Q000000981:diagnostic imaging*; D006689:Hodgkin Disease / Q000175:diagnosis*; D006801:Humans; D008297:Male; D010257:Paraneoplastic Syndromes / Q000000981:diagnostic imaging*; D019275:Radiopharmaceuticals; D013669:Technetium Tc 99m Medronate / Q000031:analogs & derivatives*; D055815:Young Adult
chemical_list: D019275:Radiopharmaceuticals; C024226:technetium Tc 99m hydroxymethylene diphosphonate; D013669:Technetium Tc 99m Medronate
keywords: Bone scan; Lymphoma; Paraneoplastic syndrome