title: Epidemiologic Study on Kawasaki Disease in Korea, 2007-2014: Based on Health Insurance Review & Assessment Service Claims.
abstract: The aim of this study is to assess the actual epidemiologic features of Kawasaki disease (KD) in Korea using the data from Health Insurance Review & Assessment Service (HIRA) claims from 2007 to 2014. We investigated HIRA claims of patients who had KD (International Classification of Diseases-10, M30.3) as a major diagnosis and were given intravenous immunoglobulin (IVIG) from 2007 to 2014. A total of 39,082 patients were reported during the period. The male-to-female ratio was 1.42 and the median age was 28 months. The incidence rates were 168.3 per 100,000 population aged 0 to 4 years in 2007, 159.1 in 2008, 167.3 in 2009, 190.4 in 2010, 188.2 in 2011, 190.2 in 2012, 210.4 in 2013 and 217.2 in 2014. These rates were much higher than those in the previous studies in Korea. KD occurred more often in early summer (May, June and July) and winter (December and January). The annual incidence rate of KD had been increasing every year, reaching 217.2 per 100,000 population aged 0 to 4 years in 2014. It is the second highest incidence rate of KD in the world after Japan.
authors: Healthcare Review and Assessment Committee, Health Insurance Review & Assessment Service, Seoul, Korea. hsm150101@gmail.com, hsm150101@hira.or.kr.
authors: Sangmi
authors: http://orcid.org/0000-0002-6069-5946
authors: S
authors: Ha
authors: Healthcare Review and Assessment Committee, Health Insurance Review & Assessment Service, Seoul, Korea.
authors: Gi Hyeon
authors: http://orcid.org/0000-0001-7414-0258
authors: GH
authors: Seo
authors: Department of Pediatrics, Severance Children's Hospital, Yonsei University, Seoul, Korea.
authors: Kyu Yeun
authors: http://orcid.org/0000-0002-8035-4436
authors: KY
authors: Kim
authors: Department of Pediatrics, Severance Children's Hospital, Yonsei University, Seoul, Korea.
authors: Dong Soo
authors: http://orcid.org/0000-0002-3270-506X
authors: DS
authors: Kim
mesh_terms: D000293:Adolescent; D000367:Age Factors; D002648:Child; D002675:Child, Preschool; D016208:Databases, Factual; D005260:Female; D006801:Humans; D015994:Incidence; D007223:Infant; D007344:Insurance Claim Reporting; D008297:Male; D009080:Mucocutaneous Lymph Node Syndrome / Q000453:epidemiology*; D056910:Republic of Korea / Q000453:epidemiology; D012737:Sex Factors
keywords: Annual Incidence; Epidemiology; Kawasaki Disease; Korea