title: Multidrug-resistant tuberculosis patients lost to follow-up: self-reported readiness to restart treatment.
abstract: Multidrug-resistant tuberculosis (MDR-TB) patients lost to follow-up (LTFU) from Programmatic Management of Drug-resistant Tuberculosis facilities in the Philippines.
  
  
  
  To gain insight into patients' readiness to return to treatment.
  
  
  
  MDR-TB patients who initiated treatment and were categorized as LTFU were identified using TB registers, contacted, and asked to consent to an interview and medical record review. At the conclusion of the interview, patients' readiness to restart treatment was assessed and examined in relation to demographic, clinical, and interview data. Odds ratios were calculated.
  
  
  
  When asked if they would consider restarting MDR-TB treatment, 3% of the 89 participating patients reported that they had already restarted, 34% indicated that they wanted to restart, 33% had not considered restarting, 28% were undecided, and 2% had decided against restarting. Patients who wanted to restart treatment were more likely to report having borrowed money for TB-related expenses (OR 5.97, 95%CI 1.27-28.18), and were less likely to report being self-employed (OR 0.08, 95%CI 0.01-0.67), or perceive themselves at low or no risk for TB relapse (OR 0.30, 95%CI 0.08-0.96) than patients who did not indicate an interest in restarting treatment.
  
  
  
  Efforts to re-engage LTFU patients in care should consider financial barriers, knowledge gaps, and personal adherence challenges in patients.
authors: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
authors: J M
authors: JM
authors: Mangan
authors: Tropical Disease Foundation, Makati City, The Philippines.
authors: T E
authors: TE
authors: Tupasi
authors: National Tuberculosis Control Program, Department of Health, Manila, The Philippines.
authors: A M C G
authors: AM
authors: Garfin
authors: National Center for Pulmonary Research, Lung Center of the Philippines, Quezon City, The Philippines.
authors: V
authors: V
authors: Lofranco
authors: Philippine Business for Social Progress-Innovations and Multisectoral Partnership to Achieve Control of Tuberculosis Project, Manila, The Philippines.
authors: R
authors: R
authors: Orillaza-Chi
authors: National Tuberculosis Control Program, Department of Health, Manila, The Philippines.
authors: R
authors: R
authors: Basilio
authors: Tropical Disease Foundation, Makati City, The Philippines.
authors: L C
authors: LC
authors: Naval
authors: Tropical Disease Foundation, Makati City, The Philippines.
authors: G I
authors: GI
authors: Balane
authors: Tropical Disease Foundation, Makati City, The Philippines.
authors: E S
authors: ES
authors: Joson
authors: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
authors: D
authors: D
authors: Burt
authors: World Health Organization Regional Office for the Western Pacific, Manila, The Philippines.
authors: W-J
authors: WJ
authors: Lew
authors: Advisor to the National Tuberculosis Program, Manila, The Philippines.
authors: M
authors: M
authors: Mantala
authors: National Center for Pulmonary Research, Lung Center of the Philippines, Quezon City, The Philippines.
authors: S
authors: S
authors: Pancho
authors: Tropical Disease Foundation, Makati City, The Philippines.
authors: J N
authors: JN
authors: Sarol
authors: US Agency for International Development, Washington DC, USA.
authors: A
authors: A
authors: Golubkov
authors: Centers for Disease Control and Prevention, Atlanta, Georgia, USA.
authors: E V
authors: EV
authors: Kurbatova
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000995:Antitubercular Agents / Q000627:therapeutic use; D016022:Case-Control Studies; D015331:Cohort Studies; D005260:Female; D006801:Humans; D059012:Lost to Follow-Up; D008297:Male; D008875:Middle Aged; D010679:Philippines / Q000453:epidemiology; D057566:Self Report; D012959:Socioeconomic Factors; D018088:Tuberculosis, Multidrug-Resistant / Q000188:drug therapy* / Q000453:epidemiology*; D055815:Young Adult; D016903:Drug Monitoring
chemical_list: D000995:Antitubercular Agents