title: The immunogenic properties of a highly purified insulin preparation.
abstract: Twenty patients who had never previously received insulin were treated with a highly purified preparation (NPH LEO in R.I. quality). Insulin antibody estimations were performed over a 14 to 19 month period. Detectable amounts of antibodies were formed by 18 of the 20 patients. The levels were lower than those found in patients on conventional insulins but moderate levels were found in 7 patients. No correlation was found between the development of antibodies and changes in insulin requirement.
authors: The Diabetes and Endocrine Unit, The Mater Misericordiae Hospital, Dublin 7.
authors: N T
authors: NT
authors: Manning
authors: The Diabetes and Endocrine Unit, The Mater Misericordiae Hospital, Dublin 7.
authors: M I
authors: MI
authors: Drury