title: Erdheim-Chester disease with bilateral Achilles tendon involvement.
abstract: Erdheim-Chester disease (ECD) is a rare non-Langerhans cell histiocytosis with a broad spectrum of organ manifestations, presenting with characteristic radiological and histological findings. Soft tissue manifestations (xanthogranulomas) have been reported to be most commonly found in the region of the orbits. We report bilateral Achilles tendon xanthogramlomas in a 36-year-old male with biopsy-proven and B-RAF V600E-positive ECD. Although rare, ECD should be considered in the differential diagnosis of intratendinous masses.
authors: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany. jonathan.nadjiri@tum.de.
authors: Jonathan
authors: http://orcid.org/0000-0003-0698-965X
authors: J
authors: Nadjiri
authors: Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.|Wilhelm Sander Bone and Soft Tissue Sarcoma Center, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.
authors: Klaus
authors: K
authors: Woertler
authors: Wilhelm Sander Bone and Soft Tissue Sarcoma Center, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.|Institute of Pathology, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.
authors: Katja
authors: K
authors: Specht
authors: Department of Orthopedic Surgery, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.
authors: Norbert
authors: N
authors: Harrasser
authors: Wilhelm Sander Bone and Soft Tissue Sarcoma Center, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.|Department of Orthopedic Surgery, Klinikum rechts der Isar, Technische Universität München, Ismaninger Str. 22, D-81675, Munich, Germany.
authors: Andreas
authors: A
authors: Toepfer
mesh_terms: D000125:Achilles Tendon / Q000000981:diagnostic imaging* / Q000473:pathology*; D000328:Adult; D003937:Diagnosis, Differential; D031249:Erdheim-Chester Disease / Q000000981:diagnostic imaging* / Q000235:genetics / Q000473:pathology*; D006801:Humans; D008297:Male; D048493:Proto-Oncogene Proteins B-raf / Q000235:genetics; D052256:Tendinopathy / Q000000981:diagnostic imaging* / Q000473:pathology*
chemical_list: C482119:BRAF protein, human; D048493:Proto-Oncogene Proteins B-raf
keywords: Achilles tendon; B-RAF mutation; Erdheim-Chester disease; Xanthogranuloma