title: Sero-Negative Systemic Sclerosis: A Rare Presentation.
abstract: Systemic Sclerosis is a multisystem disease associated with progressive fibrosis of skin and internal organs. It is diagnosed by presence of characteristic clinical findings and is supported by specific serologic abnormalities. ANA is positive in case of systemic sclerosis in 90 percent of cases. We report a rare case of this rare disease where patient was ANA, Antitopoisomerase I (anti-Scl-70), Anticenteromere antibody negative.
authors: Assistant Professor, Department of Medicine, Government Medical College , Amritsar, India .
authors: Rakesh
authors: R
authors: Chander
authors: Principal and Head, Department of Medicine, Government Medical College , Amritsar, India .
authors: Santokh
authors: S
authors: Singh
authors: Post Graduate Student, Department of Medicine, Government Medical College , Amritsar, India .
authors: Siddhesh Arun
authors: SA
authors: Kalantri
authors: Associate Professor, Department of Medicine, Government Medical College , Amritsar, India .
authors: Shiv
authors: S
authors: Charan
authors: Post Graduate Student, Department of Medicine, Government Medical College , Amritsar, India .
authors: Abhishek
authors: A
authors: Gupta
keywords: Anticenteromere; Antinuclear antibody; Antitopoisomerase I