title: Discrimination and Integration of Stress Signals by Pathogenic Bacteria.
abstract: For pathogenic bacteria, the ability to sense and respond to environmental stresses encountered within the host is critically important, allowing them to adapt to changing conditions and express virulence genes appropriately. This review considers the diverse molecular mechanisms by which stress conditions are sensed by bacteria, how related signals are discriminated, and how stress responses are integrated, highlighting recent studies in selected bacterial pathogens of clinical relevance.
authors: Department of Microbiology, University of Washington School of Medicine, Seattle, WA, 98195, USA.|Department Laboratory Medicine, University of Washington School of Medicine, Seattle, WA, 98195, USA.
authors: Ferric C
authors: FC
authors: Fang
authors: Department Laboratory Medicine, University of Washington School of Medicine, Seattle, WA, 98195, USA.
authors: Elaine R
authors: ER
authors: Frawley
authors: Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.
authors: Timothy
authors: T
authors: Tapscott
authors: Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, 80045, USA.|Veterans Affairs Eastern Colorado Health Care System, 1055 Clermont Street, Denver, CO 80220, USA.
authors: Andrés
authors: A
authors: Vázquez-Torres
mesh_terms: D000222:Adaptation, Physiological; D018407:Bacterial Physiological Phenomena; D001426:Bacterial Proteins / Q000737:chemistry / Q000378:metabolism; D054884:Host-Pathogen Interactions; D015398:Signal Transduction; D013312:Stress, Physiological
chemical_list: D001426:Bacterial Proteins