title: Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection.
abstract: Listeria monocytogenes, a well-described cause of encephalitis and abortion in ruminants and of food-borne illness in humans, is rarely associated with disease in companion animals. A case of urinary tract infection associated with an atypical, weakly hemolytic L. monocytogenes strain is described in a diabetic dog. The serotype of the L. monocytogenes isolate was determined to be 1/2a (3a), with the multilocus genotyping pattern 2.72_1/2a. A nucleotide substitution (Gly145Asp) was detected at residue 145 in the promoter prfA region. This residue is within the critical helix-turn-helix motif of PrfA. The source of the L. monocytogenes strain remains unknown, and the dog recovered after a 4-week course of cephalexin (30 mg/kg orally twice daily).
authors: Departments of Clinical Sciences (Palerme, Pan), Food, Bioprocessing & Nutrition Sciences (Parsons, Kathariou), and Population Health & Pathobiology (Jacob), North Carolina State University, Raleigh, NCAgricultural Research Service, U.S. Department of Agriculture, Peoria, IL (Ward).
authors: Jean-Sébastien
authors: JS
authors: Palerme
authors: Departments of Clinical Sciences (Palerme, Pan), Food, Bioprocessing & Nutrition Sciences (Parsons, Kathariou), and Population Health & Pathobiology (Jacob), North Carolina State University, Raleigh, NCAgricultural Research Service, U.S. Department of Agriculture, Peoria, IL (Ward).
authors: Po Ching
authors: PC
authors: Pan
authors: Departments of Clinical Sciences (Palerme, Pan), Food, Bioprocessing & Nutrition Sciences (Parsons, Kathariou), and Population Health & Pathobiology (Jacob), North Carolina State University, Raleigh, NCAgricultural Research Service, U.S. Department of Agriculture, Peoria, IL (Ward).
authors: Cameron T
authors: CT
authors: Parsons
authors: Departments of Clinical Sciences (Palerme, Pan), Food, Bioprocessing & Nutrition Sciences (Parsons, Kathariou), and Population Health & Pathobiology (Jacob), North Carolina State University, Raleigh, NCAgricultural Research Service, U.S. Department of Agriculture, Peoria, IL (Ward).
authors: Sophia
authors: S
authors: Kathariou
authors: Departments of Clinical Sciences (Palerme, Pan), Food, Bioprocessing & Nutrition Sciences (Parsons, Kathariou), and Population Health & Pathobiology (Jacob), North Carolina State University, Raleigh, NCAgricultural Research Service, U.S. Department of Agriculture, Peoria, IL (Ward).
authors: Todd J
authors: TJ
authors: Ward
authors: Departments of Clinical Sciences (Palerme, Pan), Food, Bioprocessing & Nutrition Sciences (Parsons, Kathariou), and Population Health & Pathobiology (Jacob), North Carolina State University, Raleigh, NCAgricultural Research Service, U.S. Department of Agriculture, Peoria, IL (Ward) megan_jacob@ncsu.edu.
authors: Megan E
authors: ME
authors: Jacob
mesh_terms: D000818:Animals; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000662:veterinary*; D003937:Diagnosis, Differential; D004283:Dog Diseases / Q000175:diagnosis* / Q000382:microbiology; D004285:Dogs; D008089:Listeria monocytogenes / Q000302:isolation & purification*; D008088:Listeriosis / Q000150:complications / Q000382:microbiology / Q000662:veterinary*; D008297:Male; D014552:Urinary Tract Infections / Q000150:complications / Q000382:microbiology / Q000662:veterinary*
keywords: Canine listeriosis; Listeria monocytogenes; canine urinary tract infection