title: Nitric oxide ameliorates the damaging effects of oxidative stress induced by iron deficiency in cyanobacterium Anabaena 7120.
abstract: In cyanobacterium Anabaena 7120, iron deficiency leads to oxidative stress with unavoidable consequences. Nitric oxide reduces pigment damage and supported the growth of Anabaena 7120 in iron-deficient conditions. Elevation in nitric oxide accumulation and reduced superoxide radical production justified the role of nitric oxide in alleviating oxidative stress in iron deficiency. Increased activities of antioxidative enzymes and higher levels of ROS scavengers (ascorbate, glutathione and thiol) in iron deficiency were also observed in the presence of nitric oxide. Nitric oxide also supported the membrane integrity of Anabaena cells and reduces protein and DNA damage caused by oxidative stress induced by iron deficiency. Results suggested that nitric oxide alleviates the damaging effects of oxidative stress induced by iron deficiency in cyanobacterium Anabaena 7120.
authors: Laboratory of Microbial Genetics, Department of Botany, Banaras Hindu University, Varanasi, 221005, India.
authors: Manish Singh
authors: MS
authors: Kaushik
authors: Laboratory of Microbial Genetics, Department of Botany, Banaras Hindu University, Varanasi, 221005, India.
authors: Meenakshi
authors: M
authors: Srivastava
authors: Laboratory of Microbial Genetics, Department of Botany, Banaras Hindu University, Varanasi, 221005, India.
authors: Alka
authors: A
authors: Srivastava
authors: Laboratory of Microbial Genetics, Department of Botany, Banaras Hindu University, Varanasi, 221005, India.
authors: Anumeha
authors: A
authors: Singh
authors: Laboratory of Microbial Genetics, Department of Botany, Banaras Hindu University, Varanasi, 221005, India. akmishraau@rediffmail.com.
authors: Arun Kumar
authors: AK
authors: Mishra
mesh_terms: D017033:Anabaena / Q000187:drug effects* / Q000378:metabolism; D000975:Antioxidants / Q000378:metabolism; D001205:Ascorbic Acid / Q000378:metabolism; D004249:DNA Damage / Q000187:drug effects; D007501:Iron / Q000378:metabolism*; D009569:Nitric Oxide / Q000378:metabolism / Q000494:pharmacology*; D018384:Oxidative Stress / Q000187:drug effects*; D013438:Sulfhydryl Compounds / Q000378:metabolism; D013481:Superoxides / Q000378:metabolism
chemical_list: D000975:Antioxidants; D013438:Sulfhydryl Compounds; D013481:Superoxides; D009569:Nitric Oxide; D007501:Iron; D001205:Ascorbic Acid
keywords: Anabaena 7120; Antioxidative enzymes; Iron deficiency; Nitric oxide; Oxidative stress; RAPD; ROS; SDS-PAGE