title: Chemical composition and antimicrobial activity of fatty acid methyl ester of Quercus leucotrichophora fruits.
abstract: Natural fats and dietary oils are chief source of fatty acids and are well known to have antimicrobial activities against various microbes. The chemical composition and antimicrobial activities of fatty acids from fruits of white Oak (Quercus leucotrichophora) are yet unexplored and therefore the present study for the first time determines the fatty acid composition, and the antibacterial and antifungal activities of fatty acid methyl esters (FAME) of the white Oak plant found along the Himalayan region of Uttarakhand, India. The GCMS analysis revealed the presence of higher amount of saturated fatty acids than unsaturated fatty acids. FAME extract of fruits of Q. leucotrichophora demonstrated better antibacterial activity against Gram-positive bacteria than the Gram-negative bacteria. The present studies clearly establish the potential of the fruits of Q. leucotrichophora for use in soap, cosmetics and pharmaceutical industries.
authors: a Department of Chemistry , Dolphin Institute of Biomedical and Natural Sciences , Dehradun , India.
authors: Ankita
authors: A
authors: Sati
authors: b Department of Chemistry , H.N.B. Garhwal University , Srinagar , India.
authors: Sushil Chandra
authors: SC
authors: Sati
authors: c Department of Pharmaceutical Sciences , H.N.B. Garhwal University , Srinagar , India.
authors: Nitin
authors: N
authors: Sati
authors: b Department of Chemistry , H.N.B. Garhwal University , Srinagar , India.
authors: O P
authors: OP
authors: Sati
mesh_terms: D000900:Anti-Bacterial Agents / Q000494:pharmacology; D000890:Anti-Infective Agents / Q000737:chemistry / Q000494:pharmacology*; D000935:Antifungal Agents / Q000494:pharmacology; D004952:Esters / Q000737:chemistry / Q000494:pharmacology; D005227:Fatty Acids / Q000737:chemistry / Q000494:pharmacology*; D005638:Fruit / Q000737:chemistry*; D008401:Gas Chromatography-Mass Spectrometry; D006090:Gram-Negative Bacteria / Q000187:drug effects; D006094:Gram-Positive Bacteria / Q000187:drug effects; D007194:India; D008826:Microbial Sensitivity Tests; D029963:Quercus / Q000737:chemistry*
chemical_list: D000900:Anti-Bacterial Agents; D000890:Anti-Infective Agents; D000935:Antifungal Agents; D004952:Esters; D005227:Fatty Acids
keywords: Quercus leucotrichophora; White Oak; antibacterial activity; antifungal activity; fatty acid methyl esters