title: IgG4-related Disease with Bone Marrow Involvement.
abstract: A 61-year-old Japanese woman with anemia, submandibular gland swelling, and enlarged lymph nodes was diagnosed with IgG4-related disease (IgG4-RD) by lymph node biopsy. Bone marrow involvement of IgG4-RD was detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) and immunohistochemically proven by bone marrow biopsy in this patient. Anemia progressed gradually, and prednisolone treatment was initiated. Anemia and submandibular gland swelling improved soon after prednisolone treatment was initiated. We report a rare case of IgG4-RD involving the bone marrow. FDG-PET/CT and bone marrow biopsy were useful for diagnosis in this case.
authors: Department of Hematology/Oncology, Tokai University Hachioji Hospital, Japan.
authors: Akifumi
authors: A
authors: Ichiki
authors: Norisato
authors: N
authors: Hashimoto
authors: Tomoki
authors: T
authors: Ueda
authors: Shinichiro
authors: S
authors: Hiraiwa
authors: Takuma
authors: T
authors: Tajiri
authors: Naoya
authors: N
authors: Nakamura
authors: Kiyoshi
authors: K
authors: Ando
authors: Kenji
authors: K
authors: Yokoyama
mesh_terms: D001327:Autoimmune Diseases / Q000175:diagnosis* / Q000000981:diagnostic imaging; D001853:Bone Marrow / Q000473:pathology*; D005260:Female; D006801:Humans; D007074:Immunoglobulin G / Q000097:blood*; D008875:Middle Aged; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods; D014057:Tomography, X-Ray Computed / Q000379:methods
chemical_list: D007074:Immunoglobulin G