title: Adherence to Childhood Tuberculosis Treatment in Mozambique.
abstract: There is limited literature regarding adherence rates for the treatment of tuberculosis (TB) in children. We aimed to describe TB treatment outcomes and adherence as well as to evaluate associated factors to poor adherence in Mozambican children.
  
  
  
  This is a sub-study of a community TB incidence study among children <3 years of age. Incomplete adherence included the sum of lost-to-follow-up cases plus those with a delay of > 3 weeks to treatment completion.
  
  
  
  Fifty TB treatments were assessed. Forty-four (88.0%) patients completed treatment, two (4.0%) died during treatment and four (8.0%) were lost to follow-up. Incomplete adherence was observed in 31.3% (15 of 48) of cases and was associated with malnutrition or history of a migrant mother.
  
  
  
  Although treatment outcome is overall good, there is still a significant proportion of incomplete adherence. Further larger paediatric TB cohorts and qualitative approaches are needed to assess and confirm potential factors for non-adherence.
authors: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat De Barcelona, Barcelona, Spain c/ Rosselló, 132, 5° 2 (08036).|Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique Rua 12, Cambeve, Vila de Manhiça, CP 1929.
authors: Elisa
authors: E
authors: Lopez-Varela
authors: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat De Barcelona, Barcelona, Spain c/ Rosselló, 132, 5° 2 (08036).|Preventive Medicine and Epidemiology Service, Hospital Clínic of Barcelona, Barcelona, SpainVillarroel, 170 08036 Barcelona.
authors: Victor Guillermo
authors: VG
authors: Sequera
authors: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat De Barcelona, Barcelona, Spain c/ Rosselló, 132, 5° 2 (08036).|Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique Rua 12, Cambeve, Vila de Manhiça, CP 1929.|Amsterdam Institute for Global Health and Development (AIGHD), Amsterdam, the Netherlands Pietersbergweg 17 1105 BM Amsterdam ZO.
authors: Alberto L
authors: AL
authors: García-Basteiro
authors: Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique Rua 12, Cambeve, Vila de Manhiça, CP 1929.
authors: Orvalho Joaquim
authors: OJ
authors: Augusto
authors: Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique Rua 12, Cambeve, Vila de Manhiça, CP 1929.|Faculdade De Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique Av. Julius Nyerere-Campus Universitário, C.P. 254 Maputo.
authors: Khatia
authors: K
authors: Munguambe
authors: Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique Rua 12, Cambeve, Vila de Manhiça, CP 1929.|Faculdade De Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique Av. Julius Nyerere-Campus Universitário, C.P. 254 Maputo.
authors: Jahit
authors: J
authors: Sacarlal
authors: ISGlobal, Barcelona Ctr. Int. Health Res. (CRESIB), Hospital Clínic - Universitat De Barcelona, Barcelona, Spain c/ Rosselló, 132, 5° 2 (08036).|Centro de Investigação em Saúde de Manhiça (CISM), Manhiça, Mozambique Rua 12, Cambeve, Vila de Manhiça, CP 1929.
authors: Pedro L
authors: PL
authors: Alonso
mesh_terms: D000995:Antitubercular Agents / Q000627:therapeutic use*; D002675:Child, Preschool; D005260:Female; D006297:Health Services Accessibility; D006801:Humans; D007223:Infant; D059012:Lost to Follow-Up; D008297:Male; D009073:Mozambique / Q000453:epidemiology; D011446:Prospective Studies; D012959:Socioeconomic Factors; D016896:Treatment Outcome; D014376:Tuberculosis / Q000188:drug therapy* / Q000401:mortality
chemical_list: D000995:Antitubercular Agents
keywords: adherence; childhood; treatment.; tuberculosis