title: Carotid artery stenting with a new-generation double-mesh stent in three high-volume Italian centres: clinical results of a multidisciplinary approach.
abstract: OBJECTIVE
  Carotid artery stenting (CAS) is still associated with higher periprocedural cerebrovascular events (CEs) compared to vascular surgery. The Roadsaver carotid artery stent is a double layer micromesh stent which reduces plaque prolapse and embolisation by improving plaque coverage. Its clinical impact on neurological outcome was unknown. The aim of this study was therefore to report the clinical results of a large real-world population from three different centres receiving a Roadsaver stent to treat carotid artery disease.
  
  
  RESULTS
  One hundred and fifty (150) patients (age 74±8 yrs, 75% male, symptomatic 29%) treated with CAS using the Roadsaver carotid stent in three high-volume Italian centres were included in the study. Intraprocedural optical coherence tomography (OCT) evaluation was performed in 26 patients, with an off-line analysis by a dedicated core laboratory. All patients underwent duplex ultrasound and neurological evaluation at 24 hours and at 30 days. CAS was technically successful in all cases (stent diameter: 8.6±0.8 mm, stent length: 25.0±4.5 mm). No in-hospital or 30-day CEs were observed. OCT evaluation detected a low rate of plaque prolapse (two patients, 7.7%). Duplex ultrasound showed stent and external carotid artery patency in all cases both before discharge and at 30-day follow-up.
  
  
  CONCLUSIONS
  The Roadsaver stent is a safe and promising technology for CAS, with a low percentage of plaque prolapse and good short-term clinical outcome. Larger studies with longer follow-up are necessary to confirm this favourable clinical outcome.
authors: Interventional Cardiology Unit, Maria Cecilia Hospital, Cotignola, Italy.
authors: Roberto
authors: R
authors: Nerla
authors: Fausto
authors: F
authors: Castriota
authors: Antonio
authors: A
authors: Micari
authors: Paolo
authors: P
authors: Sbarzaglia
authors: Gioel Gabrio
authors: GG
authors: Secco
authors: Maria Antonella
authors: MA
authors: Ruffino
authors: Gianmarco
authors: G
authors: de Donato
authors: Carlo
authors: C
authors: Setacci
authors: Alberto
authors: A
authors: Cremonesi
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D000800:Angioplasty, Balloon / Q000379:methods; D002340:Carotid Artery Diseases / Q000628:therapy*; D017536:Carotid Artery, Common / Q000601:surgery*; D002343:Carotid Artery, Internal / Q000601:surgery*; D016893:Carotid Stenosis / Q000628:therapy*; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D015607:Stents; D013526:Surgical Mesh; D041623:Tomography, Optical Coherence / Q000379:methods; D016896:Treatment Outcome; D014656:Vascular Surgical Procedures