title: Outcomes of photorefractive keratectomy instead of phototherapeutic keratectomy for patients with granular corneal dystrophy type 2.
abstract: OBJECTIVE
  The purpose of this study was to evaluate visual function and postoperative refractive errors in patients with granular corneal dystrophy type 2 (GCD2) and cataracts who underwent photorefractive keratectomy (PRK) instead of phototherapeutic keratectomy (PTK) following cataract surgery to avoid PTK-induced central island formation and reduce refractive errors after cataract surgery.
  
  
  METHODS
  The medical records of 14 eyes from nine patients (one man and eight women; mean age, 69.0 ± 8.5 years) with GCD2 and cataracts were evaluated. All patients underwent PTK using the PRK mode 3 months after cataract surgery. We analyzed corrected distance visual acuity (CDVA), refractive errors, and corneal astigmatism derived from Fourier analysis and assessed the incidence of complications in cataract surgery and PTK.
  
  
  RESULTS
  The mean CDVA logMAR values were 0.42 ± 0.19, 0.38 ± 0.18, and 0.16 ± 0.12 before and after cataract surgery and after PTK, respectively. CDVA improved significantly after PTK, as compared with both before and after cataract surgery (P < 0.001). The mean absolute errors after cataract surgery and PTK were 0.53 ± 0.43 and 1.61 ± 1.01 diopters, respectively. Pre- and postoperative Fourier indices did not significantly vary in the 3-mm diameter zone, and only the asymmetry component of the 6-mm diameter zone significantly (P <0.01) increased postoperatively. No central island formation and no other marked complications were observed postoperatively in any case.
  
  
  CONCLUSIONS
  Performing PTK using the PRK mode following cataract surgery may be effective for patients with GCD2 and cataracts.
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Fumika
authors: F
authors: Oya
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. soma@ophthal.med.osaka-u.ac.jp.
authors: Takeshi
authors: T
authors: Soma
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Yoshinori
authors: Y
authors: Oie
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Takeshi
authors: T
authors: Nakao
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Shizuka
authors: S
authors: Koh
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Motokazu
authors: M
authors: Tsujikawa
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Naoyuki
authors: N
authors: Maeda
authors: Department of Ophthalmology, Osaka University Graduate School of Medicine, Room E7, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
authors: Kohji
authors: K
authors: Nishida
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002386:Cataract / Q000503:physiopathology; D003317:Corneal Dystrophies, Hereditary / Q000503:physiopathology / Q000601:surgery*; D019781:Corneal Topography; D005260:Female; D005583:Fourier Analysis; D006801:Humans; D019654:Lens Implantation, Intraocular; D008297:Male; D008875:Middle Aged; D009216:Myopia / Q000503:physiopathology / Q000601:surgery*; D018918:Phacoemulsification; D018903:Photorefractive Keratectomy; D012029:Refraction, Ocular / Q000502:physiology; D041623:Tomography, Optical Coherence; D016896:Treatment Outcome; D014792:Visual Acuity / Q000502:physiology
keywords: Avellino corneal dystrophy; Cataract; Granular corneal dystrophy type 2; Photorefractive keratectomy; Phototherapeutic keratectomy