title: Molecular and pathological characterization of Fusarium solani species complex infection in the head and lateral line system of Sphyrna lewini.
abstract: A severe fungal infection affecting the head and lateral line system was diagnosed in 7 captive scalloped hammerhead sharks Sphyrna lewini in an aquarium in Thailand. Extensive and severe necrotizing cellulitis was consistently observed microscopically along the cephalic and lateral line canals in conjunction with positive fungal cultures for Fusarium sp. Molecular phylogenetic analysis was performed from 3 isolates based on the nucleotide sequences containing internally transcribed spacer (ITS) and a portion of 5.8S and 28S rDNA. The fungus was highly homologous (100%) and closely related to F. solani species complex 2 (FSSC 2), which belongs to Clade 3 of the FSSC. Our results illustrate the histopathological findings and expand upon our knowledge of the prevalence of invasive fusariosis in the head and lateral line system of hammerhead sharks.
authors: STAR Wildlife, Exotic and Aquatic Pathology, Department of Pathology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330, Thailand.
authors: Nopadon
authors: N
authors: Pirarat
authors: Komsil
authors: K
authors: Sahatrakul
authors: Sitthichok
authors: S
authors: Lacharoje
authors: Eric
authors: E
authors: Lombardini
authors: Nantarika
authors: N
authors: Chansue
authors: Somporn
authors: S
authors: Techangamsuwan
mesh_terms: D000818:Animals; D004271:DNA, Fungal / Q000145:classification / Q000235:genetics; D021901:DNA, Intergenic / Q000145:classification / Q000235:genetics; D005393:Fish Diseases / Q000382:microbiology* / Q000473:pathology; D060585:Fusariosis / Q000473:pathology / Q000662:veterinary*; D005670:Fusarium / Q000145:classification* / Q000302:isolation & purification; D053403:Lateral Line System / Q000382:microbiology* / Q000473:pathology; D010802:Phylogeny; D012331:RNA, Fungal / Q000235:genetics; D012339:RNA, Ribosomal, 28S / Q000235:genetics; D012754:Sharks
chemical_list: D004271:DNA, Fungal; D021901:DNA, Intergenic; D012331:RNA, Fungal; D012339:RNA, Ribosomal, 28S