title: Nickel-Catalyzed C-H Chalcogenation of Anilines.
abstract: The C-H thiolation of aniline derivatives was accomplished with a versatile nickel(II) catalyst under ligand-free conditions. The robust nature of the nickel catalysis system was reflected by the C-H thiolation with a good functional group tolerance and an ample scope, employing anilines possessing removable directing groups. The widely applicable nickel catalyst also allowed for aniline C-H selenylations, while mechanistic studies provided strong support that the rate-determining step is the C-H activation.
authors: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstraße 2, 37077, Göttingen, Germany.
authors: Thomas
authors: T
authors: Müller
authors: Institut für Organische und Biomolekulare Chemie, Georg-August-Universität, Tammannstraße 2, 37077, Göttingen, Germany. Lutz.Ackermann@chemie.uni-goettingen.de.
authors: Lutz
authors: http://orcid.org/0000-0001-7034-8772
authors: L
authors: Ackermann
keywords: C−H activation; nickel; reaction mechanisms; selenylation; sulfenylation