title: Risk Factors for Glaucoma in a Cohort of Patients with Fuchs Heterochromic Iridocyclitis.
abstract: OBJECTIVE
  To describe the incidence and risk factors for ocular hypertension and/or glaucoma in patients with Fuchs heterochromic iridocyclitis (FHC).
  
  
  METHODS
  Retrospective analysis of 88 patients with FHC. Kaplan-Meier curves estimated the time to develop cataract and ocular hypertension/glaucoma. Possible prognostic factors were investigated in univariate Kaplan-Meier analyses using the Mantel-Cox logrank test.
  
  
  RESULTS
  At presentation with FHC, 52% of patients had a cataract and 26% of patients had ocular hypertension/glaucoma. The estimated percentage of patients with a cataract or ocular hypertension/glaucoma by 4 years after presentation was 71% (CI: 58-81%) and 39% (CI: 28-51%), respectively. Patients aged ≥50 years had significantly greater risk of developing glaucoma (p = 0.0065). After adjusting for age-group, having a cataract at presentation was associated with increased risk of glaucoma (p = 0.032).
  
  
  CONCLUSIONS
  Risk factors for development of ocular hypertension/glaucoma were increasing patient age and having a cataract at presentation with FHC.
authors: a Department of Ophthalmology , Alfred Hospital , Melbourne , Victoria , Australia.|c Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Ophthalmology, University of Melbourne , Department of surgery , Melbourne , Victoria , Australia.
authors: Jason T
authors: JT
authors: Toniolo
authors: a Department of Ophthalmology , Alfred Hospital , Melbourne , Victoria , Australia.|b Eye Surgery Associates , Melbourne , Victoria , Australia.
authors: Anthony J
authors: AJ
authors: Hall
authors: d Plain Statistics Pty Ltd , Horsham , Victoria , Australia.
authors: Jennifer G
authors: JG
authors: Smith
authors: e Department of Ophthalmology , Ben-Gurion University of the Nagev , Ba'er Sheva , Israel.
authors: Jaime
authors: J
authors: Levy
authors: b Eye Surgery Associates , Melbourne , Victoria , Australia.|c Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Ophthalmology, University of Melbourne , Department of surgery , Melbourne , Victoria , Australia.
authors: Lyndell L
authors: LL
authors: Lim
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D002386:Cataract / Q000175:diagnosis / Q000453:epidemiology; D005260:Female; D005500:Follow-Up Studies; D005901:Glaucoma / Q000175:diagnosis / Q000453:epidemiology*; D006801:Humans; D015994:Incidence; D015863:Iridocyclitis / Q000150:complications* / Q000175:diagnosis; D008297:Male; D008875:Middle Aged; D009798:Ocular Hypertension / Q000175:diagnosis / Q000453:epidemiology; D012189:Retrospective Studies; D012307:Risk Factors; D014792:Visual Acuity / Q000502:physiology; D055815:Young Adult
keywords: Cataract; glaucoma; heterochromia; uveitis