title: Distinct Neurophysiological Mechanisms Support the Online Formation of Individual and Across-Episode Memory Representations.
abstract: Individual experiences often overlap in their content, presenting opportunities for rapid generalization across them. In this study, we show in 2 independent experiments that integrative encoding-the ability to form individual and across memory representations during online encoding-is supported by 2 distinct neurophysiological responses. Brain potential is increased gradually during encoding and fit to a trial level memory measure for individual episodes, whereas neural oscillations in the theta range (4-6 Hz) emerge later during learning and predict participants' generalization performance in a subsequent test. These results suggest that integrative encoding requires the recruitment of 2 separate neural mechanisms that, despite their co-occurrence in time, differ in their underlying neural dynamics, reflect different brain learning rates and are supportive of the formation of opposed memory representations, individual versus across-event episodes.
authors: Cognition and Brain Plasticity Group, Institute of Biomedicine Research of Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.
authors: A
authors: A
authors: Sans-Dublanc
authors: Cognition and Brain Plasticity Group, Institute of Biomedicine Research of Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.|Montreal Neurological Institute - McGill University, Montreal, QC H3A 2B4, Canada.
authors: E
authors: E
authors: Mas-Herrero
authors: Cognition and Brain Plasticity Group, Institute of Biomedicine Research of Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.|Department of Cognitive, Education and Evolutive Psychology, University of Barcelona, Barcelona, 08035, Spain.|Institute of Neurosciences, University of Barcelona, Barcelona, 08035, Spain.
authors: J
authors: J
authors: Marco-Pallarés
authors: Cognition and Brain Plasticity Group, Institute of Biomedicine Research of Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, 08908, Spain.|Department of Cognitive, Education and Evolutive Psychology, University of Barcelona, Barcelona, 08035, Spain.|Institute of Neurosciences, University of Barcelona, Barcelona, 08035, Spain.
authors: L
authors: L
authors: Fuentemilla
mesh_terms: D000328:Adult; D001921:Brain / Q000502:physiology*; D001931:Brain Mapping / Q000379:methods; D004569:Electroencephalography / Q000379:methods; D005260:Female; D006801:Humans; D007858:Learning / Q000502:physiology*; D008297:Male; D061212:Memory, Episodic; D064926:Neurophysiological Monitoring; D013647:Task Performance and Analysis; D013826:Theta Rhythm / Q000502:physiology*; D055815:Young Adult
keywords: EEG; ERP; generalization; inferential learning; theta rhythm