title: Mild Palladium Catalyzed ortho C-H Bond Functionalizations of Aniline Derivatives.
abstract: This account collects the developments and transformations which avoid the utilization of harsh reaction conditions in the field of palladium catalyzed, ortho-directed C-H activation of aniline derivatives from the first attempts to up-to-date results, including the results of our research laboratory. The discussed functionalizations performed under mild conditions include acylation, olefination, arylation, alkylation, alkoxylation reactions. Beside the optimization studies and the synthetic applications mechanistic investigations are also presented.
authors: MTA-ELTE "Lendület" Catalysis and Organic Synthesis Research Group, Institute of Chemistry. Eötvös Loránd University, Pázmány Péter stny. 1/a, Budapest, 1117, Hungary.
authors: Ms Orsolya
authors: MO
authors: Tischler
authors: MTA-ELTE "Lendület" Catalysis and Organic Synthesis Research Group, Institute of Chemistry. Eötvös Loránd University, Pázmány Péter stny. 1/a, Budapest, 1117, Hungary.
authors: Mr Balázs
authors: MB
authors: Tóth
authors: MTA-ELTE "Lendület" Catalysis and Organic Synthesis Research Group, Institute of Chemistry. Eötvös Loránd University, Pázmány Péter stny. 1/a, Budapest, 1117, Hungary.
authors: Zoltán
authors: Z
authors: Novák
keywords: Acetanilide; C−H activation; mild transformations; palladium; urea