title: Extended spectrum β-lactamase producing Shigella flexneri serotype-2 causing bacteremia in a patient with uncontrolled diabetes mellitus.
abstract: We report a case of Shigella flexneri serotype-2 causing bacteremia in an elderly gentleman with uncontrolled diabetes mellitus, who had no other apparent risk factors. Antibiotic susceptibility testing revealed that the organism was a multidrug resistant extended spectrum beta-lactamase producing straian, which was confirmed by molecular characterization. This rare case alerts both the clinician and microbiologist to a previously unaddressed risk factor of Shigella spp. causing bacteremia, as well as emerging resistant strains that are on the rise in immunocompromised patients.
authors: Department of Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
authors: Marilyn M
authors: MM
authors: Ninan
authors: Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
authors: Tarun K
authors: TK
authors: George
authors: Department of Microbiology, Christian Medical College, Vellore, Tamil Nadu, India.
authors: V
authors: V
authors: Balaji
authors: Department of Medicine, Christian Medical College, Vellore, Tamil Nadu, India.
authors: I
authors: I
authors: Ramya
mesh_terms: D000368:Aged; D016470:Bacteremia / Q000175:diagnosis* / Q000382:microbiology; D004269:DNA, Bacterial / Q000235:genetics; D048909:Diabetes Complications / Q000175:diagnosis*; D024901:Drug Resistance, Multiple, Bacterial; D004405:Dysentery, Bacillary / Q000175:diagnosis* / Q000382:microbiology; D004586:Electrophoresis; D006801:Humans; D008297:Male; D008826:Microbial Sensitivity Tests; D016133:Polymerase Chain Reaction; D065288:Serogroup; D012763:Shigella flexneri / Q000145:classification / Q000201:enzymology* / Q000302:isolation & purification; D001618:beta-Lactamases / Q000235:genetics / Q000378:metabolism*
chemical_list: D004269:DNA, Bacterial; D001618:beta-Lactamases