title: Metabolism of 2(RS),3-epiminosqualene to 24(RS),25-epiminolanosterol byGibberella fujikuroi.
abstract: The metabolic fate of 2(RS),3-epiminosqualene (Isq.), a demonstrable inhibitor of the 2,3-oxidosqualene-lanosterol cyclase, has been studied inGibberella fujikuroi. The fungus transforms Isq. to a tetracyclic product for which the 24(RS),25-epiminolanosterol (EL) formulation was indicated by chromatographic and spectral data. The results are consistent with the pathway: Isq.→2,3-imino-22, 23-oxidosqualene→EL.
authors: Plant and Fungal Lipid Group, Plant Physiology Research Unit, Richard Russell Research Center, USDA, 30613, Athens, GA.
authors: W D
authors: WD
authors: Nes
authors: Plant and Fungal Lipid Group, Plant Physiology Research Unit, Richard Russell Research Center, USDA, 30613, Athens, GA.
authors: E J
authors: EJ
authors: Parish