title: Spindle-cell rhabdomyosarcoma of the thumb: Rare site, rare tumor in a child.
abstract: Spindle-cell rhabdomyosarcoma (RMS) is a relatively recently recognized favorable variant of embryonal RMS occurring mainly in the paratesticular and head and neck regions. Cytological reports of spindle-cell RMS have been sparse in the literature and the awareness of its cytological features is not very wide among cytopathologists. A 2-year-old girl was brought to clinical attention for a progressively enlarging swelling of right thumb. Imaging studies showed it to be a soft-tissue tumor in the subcutaneous region. Fine-needle aspiration yielded moderately cellular smears composed of small, round cells and few spindle cells with tapered cytoplasm. A cytological impression of RMS was rendered, which was later confirmed as spindle-cell RMS on excision biopsy. Spindle-cell RMS, a favorable prognostic variant of embryonal RMS, should be considered in the cytologic diagnosis of soft-tissue tumors with round cell and spindle cell morphology. This is especially true for tumors occurring in hitherto unreported sites. Diagn. Cytopathol. 2016;44:1094-1097. © 2016 Wiley Periodicals, Inc.
authors: Department of Pathology, Chacha Nehru Bal Chikitsalaya, New Delhi, India.
authors: Sonam
authors: S
authors: Mahana
authors: Department of Pathology, Chacha Nehru Bal Chikitsalaya, New Delhi, India.
authors: Reena
authors: R
authors: Tomar
authors: Department of Orthopaedics, Chacha Nehru Bal Chikitsalaya, New Delhi, India.
authors: Anil
authors: A
authors: Agarwal
authors: Department of Pathology, Chacha Nehru Bal Chikitsalaya, New Delhi, India.|Maulana Azad Medical College, New Delhi, India.
authors: Divya
authors: D
authors: Sharma
authors: Department of Pathology, Chacha Nehru Bal Chikitsalaya, New Delhi, India.|Maulana Azad Medical College, New Delhi, India.
authors: Nita
authors: N
authors: Khurana
authors: Department of Pathology, Chacha Nehru Bal Chikitsalaya, New Delhi, India.
authors: Ruchika
authors: R
authors: Gupta
mesh_terms: D044963:Biopsy, Fine-Needle; D002675:Child, Preschool; D005260:Female; D006801:Humans; D035583:Rare Diseases / Q000473:pathology*; D018233:Rhabdomyosarcoma, Embryonal / Q000473:pathology*; D012983:Soft Tissue Neoplasms / Q000473:pathology*; D013933:Thumb / Q000473:pathology*
keywords: aspiration cytology; pediatric; rhabdomyosarcoma; spindle cell; thumb