title: Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'.
abstract: The cytoskeleton is the major intracellular structure that determines the morphology of neurons and maintains their structural integrity. It is therefore not surprising that a disturbance of cytoskeletal structure and functionunderlies many neurodegenerative diseases. This special issue brings together current information on the three majorneuronal cytoskeletal filament systems, microtubules, microfilaments and neurofilaments, and aims to provide a comprehensive overview of the role of the key components of these three systems under both physiological and pathological conditions. It therefore also addresses the role of microtubule-associated proteins (with a focus on tau) and motor proteins (with a focus on kinesin).
authors: Neurobiologie der Universität Osnabrück, Barbarastrasse 11, D-49076 Osnabrück, Germany. Electronic address: brandt@biologie.uni-osnabrueck.de.
authors: Roland
authors: R
authors: Brandt
authors: Clem Jones Centre for Ageing Dementia Research, Queensland Brain Institute, The University of Queensland, St Lucia Campus, Brisbane, QLD 4072, Australia. Electronic address: j.goetz@uq.edu.au.
authors: Jürgen
authors: J
authors: Götz
mesh_terms: D000818:Animals; D003598:Cytoskeletal Proteins / Q000378:metabolism*; D006801:Humans; D019636:Neurodegenerative Diseases / Q000378:metabolism*; D009474:Neurons / Q000378:metabolism*
chemical_list: D003598:Cytoskeletal Proteins