title: Thyroid Cancer and the Chornobyl Accident in Ukraine: Experience With the Implementation of a Follow-Up Programme.
abstract: Thyroid cancer incidence, its annual variation pattern and influence of gender and age at exposure were analyzed in population groups of Ukraine exposed to ionizing radiation by the Chornobyl accident. Significant radiation risks are demonstrated in the recovery operation workers and evacuees from Prypiat town and the exclusion zone. The radiation-induced excess of thyroid cancer is confirmed among people exposed as children and adolescents and subjects who had relatively high average thyroid radiation doses. Some excess is observed in population groups exposed as adults. In the female age group of 40-49 at the moment of the accident the age-specific thyroid cancer incidence rates were significantly higher in 'high exposure' regions versus 'low exposure' ones for all the years of follow-up since 1989 until 2012. The available Ukrainian data suggest that wider survey of population with application of thyroid ultrasound examination improves the early detection of cancer and only marginally leads to bias of the completeness of registration of this disease because of 'screening effect'.
authors: State Institution 'National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine' 53, Melnykov str., Kyiv 04050, Ukraine bazyka@yahoo.com.
authors: Dimitry A
authors: DA
authors: Bazyka
authors: State Institution 'National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine' 53, Melnykov str., Kyiv 04050, Ukraine.
authors: Anatoly Ye
authors: AY
authors: Prysyazhnyuk
authors: State Institution 'National Research Center for Radiation Medicine, National Academy of Medical Sciences of Ukraine' 53, Melnykov str., Kyiv 04050, Ukraine.
authors: Mykola M
authors: MM
authors: Fuzik
authors: National Cancer Institute, 33/43 Lomonosov str., Kyiv 03022, Ukraine.
authors: Zoya P
authors: ZP
authors: Fedorenko
mesh_terms: D000293:Adolescent; D000328:Adult; D047852:Chernobyl Nuclear Accident; D002648:Child; D004190:Disasters; D005260:Female; D005500:Follow-Up Studies; D005843:Geography; D006801:Humans; D015994:Incidence; D007457:Iodine Radioisotopes / Q000032:analysis*; D008297:Male; D008875:Middle Aged; D009381:Neoplasms, Radiation-Induced / Q000000981:diagnostic imaging / Q000453:epidemiology*; D009688:Nuclear Reactors; D011829:Radiation Dosage; D012042:Registries; D012044:Regression Analysis; D012307:Risk Factors; D013961:Thyroid Gland / Q000000981:diagnostic imaging; D013964:Thyroid Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology*; D014455:Ukraine / Q000453:epidemiology
chemical_list: D007457:Iodine Radioisotopes