title: Incidence and Burden of Wheezing Disorders, Eczema, and Rhinitis in Children: findings from the Born in Bradford Cohort.
abstract: Bradford city has high infant mortality and there is a major health concern in the community due to environmental pollution. The aim of the study was to investigate the incidence and burden of wheezing disorders, eczema, and rhinitis in children aged 3-7 years .
  
  
  
  It is a prospective cohort study; the participants were 13 734 children from the Born in Bradford cohort.
  
  
  
  There were a total of 22.1% (95% Confidence Interval (CI) 21.4, 22.8%), 52.4% (95% CI 51.5%, 53.2%), and 19.3% (95% CI 18.6, 19.9%) incidence cases of wheezing disorders, eczema, and rhinitis respectively. A total of 37% (95% CI 36.2%, 37.8%), 19.5% (95% CI 18.9%, 20.2%,) and 5.9% (95% CI 5.5%, 6.3%) of the children were affected by only one, two, and three diseases respectively. Boys to girls incidence rate ratios for wheezing disorders, eczema, and rhinitis was 1.41 (95% CI 1.31, 1.51), 1.02 (95% CI 0.97, 1.07), and 1.18 (95% CI 1.09, 1.28) respectively. The respective incidence rate ratios of Pakistani to White British were 0.94 (95% CI 0.87, 1.02), 1.31 (95% CI 1.24, 1.39), and 2.03 (95% CI 1.83, 2.25) respectively.
  
  
  
  This study shows that the burden of wheezing disorders, eczema, and rhinitis in this cohort is higher than previously reported in earlier studies. In addition, it indicates that while boys are more likely to suffer from wheezing disorders, rhinitis, and multiple diseases than girls, Pakistani children are more likely to suffer from eczema, rhinitis, and multiple diseases than White British children.
authors: Centre for Reviews and Dissemination, University of York, York, UK.
authors: Teumzghi F
authors: TF
authors: Mebrahtu
authors: Division of Epidemiology and Biostatistics, School of Medicine, University of Leeds, Leeds, UK.
authors: Richard G
authors: RG
authors: Feltbower
authors: Division of Epidemiology and Biostatistics, School of Medicine, University of Leeds, Leeds, UK.
authors: Roger C
authors: RC
authors: Parslow
mesh_terms: D002648:Child; D002675:Child, Preschool; D017281:Cost of Illness; D004485:Eczema / Q000453:epidemiology* / Q000208:ethnology; D004739:England / Q000453:epidemiology / Q000208:ethnology; D005260:Female; D006801:Humans; D015994:Incidence; D008297:Male; D010154:Pakistan / Q000208:ethnology; D015995:Prevalence; D011446:Prospective Studies; D012135:Respiratory Sounds; D012220:Rhinitis / Q000453:epidemiology* / Q000208:ethnology; D017678:Sex Distribution
keywords: Wheezing disorders; eczema; rhinitis