title: [Prevention of radio-induced cancers].
abstract: The article deals with the prevention of cancers only directly related to therapeutic radiation which are distinguished from "secondary cancer". The consideration of the risk of radiation-induced cancers after radiation therapy, although it is fortunately rare events, has become indispensable today. With a review of the literature, are detailed the various involved parameters. The age of the irradiated patient is one of the main parameters. The impact of the dose is also discussed based on the model used, and based on clinical data. Other parameters defining a radiation treatment are discussed one after the other: field with the example of Hodgkin's disease, the type of radiation and the participation of secondary neutrons, spreading and splitting. All these parameters are discussed according to each organ whose sensitivity is different. The article concludes with a list of recommendations to reduce the risk of radio-induced cancers. Even with the advent of conformal radiotherapy, intensity modulation, the modulated volume arctherapy, and the development of specific machinery for the extra-cranial stereotactic, the radiation therapist must consider this risk and use of reasonable and justified control imaging. Although they constitute a small percentage of cancers that occur secondarily after a first malignant tumor, radiation-induced cancers, can not and must not be concealed or ignored and justify regular monitoring over the long term, precisely adapted on the described parameters.
authors: Département d'oncologie/radiothérapie, institut Curie, 26, rue d'Ulm, 75005 Paris, France. Electronic address: jeanmarc.cosset@gmail.com.
authors: J-M
authors: JM
authors: Cosset
authors: Service de curiethérapie, institut Gustave-Roussy, 114, rue Édouard-Vaillant, 94800 Villejuif, France; Institut de recherche biomédicale des armées, 91223 Brétigny-sur-Orge, France.
authors: C
authors: C
authors: Chargari
authors: Département de radiothérapie, institut de cancérologie de l'Ouest, boulevard J.-Monod, 44800 Saint-Herblain, Nantes, France; Unité Inserm 1018, 114, rue Édouard-Vaillant, 94805 Villejuif, France.
authors: C
authors: C
authors: Demoor
authors: Hôpital européen Georges-Pompidou, université Paris-Descartes, Paris-Cité Sorbonne, 20, rue Leblanc, 75015 Paris, France.
authors: P
authors: P
authors: Giraud
authors: Département d'oncologie/radiothérapie, institut Curie, 26, rue d'Ulm, 75005 Paris, France.
authors: S
authors: S
authors: Helfre
authors: Département d'oncologie radiothérapie, centre hospitalier Lyon-Sud, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, Lyon, France.
authors: F
authors: F
authors: Mornex
authors: Département d'oncologie/radiothérapie, institut Curie, 26, rue d'Ulm, 75005 Paris, France.
authors: A
authors: A
authors: Mazal
mesh_terms: D000293:Adolescent; D000328:Adult; D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D002648:Child; D002675:Child, Preschool; D005260:Female; D006689:Hodgkin Disease / Q000532:radiotherapy; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D008875:Middle Aged; D009369:Neoplasms / Q000532:radiotherapy; D009381:Neoplasms, Radiation-Induced / Q000517:prevention & control*; D016609:Neoplasms, Second Primary / Q000209:etiology / Q000517:prevention & control; D009928:Organ Specificity; D058958:Organs at Risk; D011471:Prostatic Neoplasms / Q000532:radiotherapy; D011836:Radiation Tolerance; D011878:Radiotherapy / Q000009:adverse effects* / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D012306:Risk; D055815:Young Adult
keywords: Age; Cancer radio-induit; Cancer secondaire; Champ; Dose; Field; IGRT; Radio-induced cancer; Secondary cancer; Âge