title: Small-bowel capsule endoscopy with panoramic view: results of the first multicenter, observational study (with videos).
abstract: OBJECTIVE
  The first small-bowel video-capsule endoscopy (VCE) with 360° panoramic view has been developed recently. This new capsule has wire-free technology, 4 high-frame-rate cameras, and a long-lasting battery life. The aim of the present study was to assess the performance and safety profile of the 360° panoramic-view capsule in a large series of patients from a multicenter clinical practice setting.
  
  
  METHODS
  Consecutive patients undergoing a 360° panoramic-view capsule procedure in 7 European Institutions between January 2011 and November 2015 were included. Both technical (ie, technical failures, completion rate) and clinical (ie, indication, findings, retention rate) data were collected by means of a structured questionnaire. VCE findings were classified according to the likelihood of explaining the reason for referral: P0, low; P1, intermediate; P2, high.
  
  
  RESULTS
  Of the 172 patients (94 men; median age, 68 years; interquartile range, 53-75), 142 underwent VCE for obscure (32 overt, 110 occult) GI bleeding (OGIB), and 28 for suspected (17) or established (2) Crohn's disease (CD). Overall, 560 findings were detected; 252 were classified as P2. The overall diagnostic yield was 40.1%; 42.2% and 30.0% in patients with OGIB and CD, respectively. The rate of complete enteroscopy was 90.2%. All patients but one, who experienced capsule retention (1/172, 0.6%), excreted and retrieved the capsule. VCE failure occurred in 4 of 172 (2.3%) patients because of technical problems.
  
  
  CONCLUSIONS
  This multicenter study, conducted in the clinical practice setting and based on a large consecutive series of patients, showed that the diagnostic yield and safety profile of the 360° panoramic-view capsule are similar to those of forward-view VCEs.
authors: Gastroenterology & Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
authors: Gian Eugenio
authors: GE
authors: Tontini
authors: Klinik für Gastroenterologie/GI-Onkologie, Allgemeines Krankenhaus Celle, Celle, Germany.
authors: Felix
authors: F
authors: Wiedbrauck
authors: Gastroenterology & Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
authors: Flaminia
authors: F
authors: Cavallaro
authors: Centre for Liver & Digestive Disorders, The Royal Infirmary of Edinburgh, Edinburgh, United Kingdom.
authors: Anastasios
authors: A
authors: Koulaouzidis
authors: Gastroenterology & Digestive Endoscopy Unit, AO Lodi, Lodi, Italy.
authors: Roberta
authors: R
authors: Marino
authors: Gastroenterology & Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
authors: Luca
authors: L
authors: Pastorelli
authors: Gastroenterology & Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy.
authors: Luisa
authors: L
authors: Spina
authors: Gastroenterology, Royal Hallamshire Hospital, Sheffield, United Kingdom.
authors: Mark E
authors: ME
authors: McAlindon
authors: Gastroenterology & Digestive Endoscopy Unit, AO Lodi, Lodi, Italy.
authors: Piera
authors: P
authors: Leoni
authors: Gastroenterology & Digestive Endoscopy Unit, AO di Melegnano, Milan, Italy.
authors: Pasquale
authors: P
authors: Vitagliano
authors: Digestive Endoscopy Unit, St. Barbara Hospital, Iglesias, Carbonia-Iglesias, Italy.
authors: Sergio
authors: S
authors: Cadoni
authors: Gastroenterology Unit, Valduce Hospital, Como, Italy.
authors: Emanuele
authors: E
authors: Rondonotti
authors: Gastroenterology & Digestive Endoscopy Unit, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy; Department of Biomedical Sciences for Health, University of Milan, Milan, Italy.
authors: Maurizio
authors: M
authors: Vecchi
mesh_terms: D000368:Aged; D053704:Capsule Endoscopy / Q000379:methods*; D003424:Crohn Disease / Q000175:diagnosis*; D005260:Female; D006471:Gastrointestinal Hemorrhage / Q000175:diagnosis*; D006801:Humans; D007421:Intestine, Small; D008297:Male; D008875:Middle Aged