title: Common variable immunodeficiency in adults requires reserved protocols for long-term follow-up.
abstract: OBJECTIVE
  The aim of this study is to establish follow-up protocols for adult patients with common variable immunodeficiency (CVID) in a recently founded adult immunology clinic in the Central Anatolia Region of Turkey, where a clinical immunology center for adults was not available previously.
  
  
  METHODS
  A total of 25 patients with CVID aged 18 years and older were included in this study. The file format consisted of 13 pages and was developed for the purpose of the study. Separate sections were designated for identity information, medical history, disease course, previous and current laboratory and imaging studies, follow-up plans, detection and management of complications/comorbidities, and treatment results.
  
  
  RESULTS
  The mean age of the patients was 36.6 ± 13.4 years. The delay in diagnosis was 107 ± 95.6 months. In 92% of patients, initial symptoms resulting in admission to healthcare facilities were infections. Seventeen of 25 patients (68%) had bronchiectasis at the beginning of follow-up.
  
  
  CONCLUSIONS
  Early identification of complications and comorbidities in patients with CVID will significantly improve quality of life and survival. Close observation and standardized protocols for follow-up are essential components of management.
authors: Department of Allergy and Clinical Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors: Ahmet Zafer
authors: AZ
authors: Çalişkaner
authors: Department of Pediatric Allergy and Clinical Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors: İsmail
authors: İ
authors: Reisli
authors: Department of Allergy and Clinical Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors: Şevket
authors: Ş
authors: Arslan
authors: Department of Allergy and Clinical Immunology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors: Ramazan
authors: R
authors: Uçar
authors: Department of Gastroenterology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors: Hüseyin
authors: H
authors: Ataseven
authors: Department of Nephrology, Meram Faculty of Medicine, Necmettin Erbakan University, Konya, Turkey.
authors: Nedim Yılmaz
authors: NY
authors: Selçuk
mesh_terms: D000328:Adult; D001987:Bronchiectasis; D017074:Common Variable Immunodeficiency; D005500:Follow-Up Studies; D006801:Humans; D008875:Middle Aged; D011788:Quality of Life; D014421:Turkey; D055815:Young Adult
keywords: CVID follow-up; CVID in adults; CVID management; Common variable immunodeficiency