title: Malignant Peripheral Nerve Sheath Tumor -A Rare Malignancy in Mandible.
abstract: Malignant Peripheral Nerve Sheath Tumor (MPNST) is biologically an aggressive tumor that is usually found in the extremities, trunk and infrequently found in the head and neck area particularly in the jaws, arising from the cells allied with nerve sheath. Mandibular MPNST may either arise from a preexisting neurofibroma or develop de novo. Because of the greater variability from case to case in overall appearance both clinically and histologically, a case of MPNST of the mandible in a 25-year-old female patient is reported. The lesion was excised and immunohistological studies (S-100 & Neuron specific enolase) were conducted to confirm the neural origin.
authors: Professor and Head of Department, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital , Rushikonda, Visakhapatnam, India .
authors: Sumit
authors: S
authors: Majumdar
authors: Senior Lecturer, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital , Rushikonda, Visakhapatnam, India .
authors: Sreekanth
authors: S
authors: Kotina
authors: Post Graduate Student, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital , Rushikonda, Visakhapatnam, India .
authors: Nirujogi
authors: N
authors: Mahesh
authors: Reader, Department of Oral pathology and Microbiology, GITAM Dental College and Hospital , Rushikonda, Visakhapatnam, India .
authors: Divya
authors: D
authors: Uppala
authors: Post Graduate Student, Department of Oral Pathology and Microbiology, GITAM Dental College and Hospital , Rushikonda, Visakhapatnam, India .
authors: Singam Praveen
authors: SP
authors: Kumar
keywords: Immunohistochemistry; Neurofibrosarcoma; Neuron specific enolase