title: Certainty of S100 from Physiology to Pathology.
abstract: S100 exists in wide variety of tissues and cell types, originally isolated from brain tissue and they are of low molecular weight proteins. S100 is evenly distributed in cytoplasm and also in nucleoplasm and is involved in both intercellular and extracellular functions. S100 protein is generally expressed in normal and also in pathological conditions. In current review, we discuss: a) update nomenclature of the various S100 proteins, b) expression of S100 in oral diseases (different soft tissue tumors, odontogenic cyst and tumor) for diagnostic value and also to know their histogenesis, c) role of S100 and RAGE receptor in oral squamous cell carcinoma.
authors: Senior Lecturer, Department of Oral Pathology and Microbiology, St Joseph Dental College , Eluru, Andhra Pradesh, India .
authors: Puneeth Horatti
authors: PH
authors: Kuberappa
authors: Senior Lecturer, Department of Oral Pathology and Microbiology, St Joseph Dental College , Eluru, Andhra Pradesh, India .
authors: Bhavana Shivanand
authors: BS
authors: Bagalad
authors: Professor, Department of Oral Pathology and Microbiology, St Joseph Dental College , Eluru, Andhra Pradesh, India .
authors: Anuradha
authors: A
authors: Ananthaneni
authors: Senior Lecturer, Department of Oral Pathology and Microbiology, St Joseph Dental College , Eluru, Andhra Pradesh, India .
authors: Md Asif
authors: MA
authors: Kiresur
authors: Professor and Head, Department of Oral Pathology and Microbiology, St Joseph Dental College , Eluru, Andhra Pradesh, India .
authors: Guduru Vijay
authors: GV
authors: Srinivas
keywords: Odontogenic cyst and tumor; Oral squamous cell carcinoma; Soft tissue tumors