title: Effects of Antiviral Agent, Acyclovir, on the Biological Fitness of Galleria mellonella (Lepidoptera: Pyralidae) Adults.
abstract: The effects of a synthetic purine nucleoside analog, antiviral agent, acyclovir (ACV), on adult longevity, fecundity, and hatchability of a serious honeycomb pest, greater wax moth Galleria mellonella L. were investigated by adding 0.01, 0.1, 1.0, and 3.0% ACV into artificial and natural diets. Control larvae were reared on diet without ACV. The artificial diet containing the lowest level of ACV, 0.01%, raised egg production from a number of 12.9 ± 0.6 to 163.2 ± 1.3. The hatching rate of these eggs was increased from 49.2 ± 2.4% to 68.2 ± 3.2%. Higher concentrations of ACV in natural food significantly increased both egg production and egg hatching rate. Female reared on old dark combs as natural diet exposed to 1.0% of ACV produced 167.5 ± 5.8 eggs with 93.2 ± 6.8% hatched. This study emphasizes the importance of determining the dietary impact of an antimicrobial agent as a food additive to a particular species of insect before its using for dietary antimicrobial purpose.
authors: Department of Molecular Biology and Genetics, Faculty of Science and Arts, Bülent Ecevit University, Zonguldak, 67100, Turkey (endericen@hotmail.com) endericen@hotmail.com.
authors: Ender
authors: E
authors: Büyükgüzel
authors: Department of Biology, Faculty of Science and Arts, Bülent Ecevit University, Zonguldak, 67100, Turkey (buyukguzelk@hotmail.com).
authors: Kemal
authors: K
authors: Büyükgüzel
keywords: Galleria mellonella; acyclovir; artificial and natural diet; fecundity; longevity