title: Data on the optimization of a GC-MS procedure for the determination of total plasma myo-inositol.
abstract: Myo-inositol (MI) is one of the stereoisomers of hexahydroxycyclohexane, which plays an important role in intracellular signal pathway. Derivatization is an indispensable step in both external and internal standard method during the chromatography-mass spectrometer (GC-MS) detection, as MI can't be ionized directly. It is valuable to optimize the derivative process and the detection volume for clinical detection. This article contains optimization data related to research publication "Quantification of plasma myo-inositol using gas chromatography-mass spectrometry" [1]. Here we introduce the data on the optimized derivatization volume, temperature, duration and the detection volume.
authors: Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China.
authors: Jin
authors: J
authors: Guo
authors: Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China; Beijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
authors: Yingfei
authors: Y
authors: Shi
authors: Chinese Academy of Inspection & Quarantine, Beijing 100023, China.
authors: Chengbao
authors: C
authors: Xu
authors: Beijing Key Laboratory of Environmental & Viral Oncology, College of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China.
authors: Rugang
authors: R
authors: Zhong
authors: Chinese Academy of Inspection & Quarantine, Beijing 100023, China.
authors: Feng
authors: F
authors: Zhang
authors: Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China; Department of Biochemistry and Molecular Biology, Shanxi Medical University, Taiyuan 030001, China.
authors: Bo
authors: B
authors: Niu
authors: Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China.
authors: Jianhua
authors: J
authors: Wang
authors: Beijing Municipal Key Laboratory of Child Development and Nutriomics, Capital Institute of Pediatrics, Beijing 100020, China.
authors: Ting
authors: T
authors: Zhang
keywords: Derivatives; Gas chromatography-mass spectrometry; Myo-inositol