title: RALFL34 regulates formative cell divisions in Arabidopsis pericycle during lateral root initiation.
abstract: In plants, many signalling molecules, such as phytohormones, miRNAs, transcription factors, and small signalling peptides, drive growth and development. However, very few small signalling peptides have been shown to be necessary for lateral root development. Here, we describe the role of the peptide RALFL34 during early events in lateral root development, and demonstrate its specific importance in orchestrating formative cell divisions in the pericycle. Our results further suggest that this small signalling peptide acts on the transcriptional cascade leading to a new lateral root upstream of GATA23, an important player in lateral root formation. In addition, we describe a role for ETHYLENE RESPONSE FACTORs (ERFs) in regulating RALFL34 expression. Taken together, we put forward RALFL34 as a new, important player in lateral root initiation.
authors: Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.
authors: Evan
authors: E
authors: Murphy
authors: Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium Department of Medical Protein Research, VIB, 9000 Ghent, Belgium Department of Biochemistry, Ghent University, 9000 Ghent, Belgium.
authors: Lam Dai
authors: LD
authors: Vu
authors: Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.
authors: Lisa
authors: L
authors: Van den Broeck
authors: Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.
authors: Zhefeng
authors: Z
authors: Lin
authors: Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK.
authors: Priya
authors: P
authors: Ramakrishna
authors: Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium.
authors: Brigitte
authors: B
authors: van de Cotte
authors: Department of Plant Biology and Genome Center, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.
authors: Allison
authors: A
authors: Gaudinier
authors: Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan.
authors: Tatsuaki
authors: T
authors: Goh
authors: Department of Cell Biology, Max Planck Institute for Developmental Biology, D- 72076 Tübingen, Germany.
authors: Daniel
authors: D
authors: Slane
authors: Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.
authors: Tom
authors: T
authors: Beeckman
authors: Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium.
authors: Dirk
authors: D
authors: Inzé
authors: Department of Plant Biology and Genome Center, University of California Davis, One Shields Avenue, Davis, CA 95616, USA.
authors: Siobhan M
authors: SM
authors: Brady
authors: Department of Biology, Graduate School of Science, Kobe University, Kobe 657-8501, Japan.
authors: Hidehiro
authors: H
authors: Fukaki
authors: Division of Plant and Crop Sciences, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, UK Department of Plant Systems Biology, VIB, B-9052 Ghent, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, B-9052 Ghent, Belgium Centre for Plant Integrative Biology, University of Nottingham, Loughborough LE12 5RD, UK ive.desmet@psb.vib-ugent.be.
authors: Ive
authors: I
authors: De Smet
mesh_terms: D017360:Arabidopsis / Q000235:genetics* / Q000254:growth & development / Q000378:metabolism; D029681:Arabidopsis Proteins / Q000235:genetics* / Q000378:metabolism; D002455:Cell Division; D018506:Gene Expression Regulation, Plant; D036361:Peptide Hormones / Q000235:genetics* / Q000378:metabolism; D018517:Plant Roots / Q000235:genetics / Q000254:growth & development / Q000378:metabolism; D014157:Transcription Factors / Q000235:genetics* / Q000378:metabolism
chemical_list: D029681:Arabidopsis Proteins; D036361:Peptide Hormones; D014157:Transcription Factors; C000624594:ralf-like 34 protein, Arabidopsis
keywords: Arabidopsis thaliana; ERF; GATA23; RAPID ALKALINIZATION FACTOR (RALF).; lateral root initiation