title: [Not Available].
abstract: OBJECTIVE
  We investigate the influence of caloric and protein deficit on mortality and length of hospital stay of critically ill patients.
  
  
  METHODS
  A cohort prospective study including 100 consecutive patients in a tertiary intensive care unit (ICU) receiving enteral or parenteral nutrition. The daily caloric and protein deficit were collected each day for a maximum of 30 days. Energy deficits were divided into critical caloric deficit (≥ 480 kcal/day) and non-critical caloric deficit (≤ 480 kcal/day); and in critical protein deficit (≥ 20 g/day) and non-critical protein deficit (≤ 20 g/day). The findings were correlated with hospital stay and mortality.
  
  
  RESULTS
  The mortality rate was 33%. Overall, the patients received 65.4% and 67.7% of the caloric and protein needs. Critical caloric deficit was found in 72% of cases and critical protein deficit in 70% of them. There was a significant correlation between length of stay and accumulated caloric deficit (R = 0.37; p < 0.001) and protein deficit (R = 0.28; p < 0.001). The survival analysis showed that mortality was greater in patients with both critical caloric (p < 0.001) and critical protein deficits (p < 0.01). The Cox regression analysis showed that critical protein deficit was associated with higher mortality (HR 0.25, 95% CI 0.07-0.93, p = 0.03).
  
  
  CONCLUSIONS
  The incidence of caloric and protein deficit in the ICU is high. Both caloric and protein deficits increase the length of hospital stay, and protein deficit greater than 20 g/day is an independent factor for mortality in critical care unit.
authors: Intensive Care Unit. Santa Rosa Hospital. Cuiaba, Brazil. aguilar@terra.com.br.
authors: Marcia Carolina
authors: MC
authors: Siqueira-Paese
authors: Diana Borges
authors: DB
authors: Dock-Nascimento
authors: José Eduardo
authors: JE
authors: De Aguilar-Nascimento
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D015331:Cohort Studies; D003422:Critical Care; D016638:Critical Illness / Q000401:mortality*; D002149:Energy Intake; D004734:Energy Metabolism; D005260:Female; D006801:Humans; D008297:Male; D044342:Malnutrition / Q000401:mortality*; D008875:Middle Aged; D011446:Prospective Studies; D011502:Protein-Energy Malnutrition / Q000401:mortality; D055815:Young Adult
keywords: Critical care. Enteral nutrition. Parenteral nutrition. Energy deficit. Mortality.