title: Solid pseudopapillary neoplasm of the ovary with metastases to the omentum and regional lymph nodes.
abstract: Extrapancreatic solid pseudopapillary neoplasms (SPNs) are rare tumors, which bear morphological, immunohistochemical, and molecular features similar to those of pancreatic counterparts. SPN occurs primarily in adolescent girls and young women. It is considered to be a malignant neoplasm with low-grade biology. Ovarian SPNs are uncommon, have benign morphology, usually limited to the ovary and local surgical excision is curative. We report an unusual case of SPN of right ovary with extraovarian spread and metastases to lymph nodes. To the best of our knowledge, this is the second documented case of extragonadal spread of ovarian SPN.
authors: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors: Gaurav Pratap Singh
authors: GP
authors: Gahlot
authors: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors: Asit Ranjan
authors: AR
authors: Mridha
authors: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors: Mukund
authors: M
authors: Sable
authors: Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
authors: Mehar Chand
authors: MC
authors: Sharma
authors: Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors: Raja
authors: R
authors: Pramanik
authors: Department of Medical Oncology, All India Institute of Medical Sciences, New Delhi, India.
authors: Lalit
authors: L
authors: Kumar
mesh_terms: D000328:Adult; D014408:Biomarkers, Tumor / Q000032:analysis; D019002:CD56 Antigen / Q000032:analysis; D002291:Carcinoma, Papillary / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D019938:Cyclin D1 / Q000032:analysis; D005260:Female; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008198:Lymph Nodes / Q000473:pathology*; D008853:Microscopy; D009362:Neoplasm Metastasis / Q000175:diagnosis* / Q000473:pathology; D015260:Neprilysin / Q000032:analysis; D009852:Omentum / Q000473:pathology*; D010051:Ovarian Neoplasms / Q000175:diagnosis* / Q000473:pathology / Q000556:secondary*; D010388:Pelvis / Q000000981:diagnostic imaging; D014057:Tomography, X-Ray Computed; D051176:beta Catenin / Q000032:analysis
chemical_list: D014408:Biomarkers, Tumor; D019002:CD56 Antigen; C522918:NCAM1 protein, human; D051176:beta Catenin; D019938:Cyclin D1; D015260:Neprilysin