title: First isolation of Clostridium indolis in a patient with chronic osteitis: a case report and literature review of human infections related to Clostridium saccharolyticum group species.
abstract: Clostridium indolis is an anaerobic spore-forming Gram-positive bacillus belonging to the Clostridium saccharolyticum group. Its clinical significance in human remains poorly known. We describe the first case of osteitis related to C. indolis, identified by MALDI-TOF mass spectrometry and provide a literature review of human infections related to C. saccharolyticum group species.
authors: Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Nice, France; Université de Nice Côte d'Azur, Inserm, C3M, Nice, France; Inserm U1065, C3M, Team6: "Bacterial Toxins in Host Pathogen Interactions", Bâtiment Universitaire Archimed, Nice, France. Electronic address: lotte.r@chu-nice.fr.
authors: Romain
authors: R
authors: Lotte
authors: Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Nice, France.
authors: Laurène
authors: L
authors: Lotte
authors: Centre de Reference des Bactéries Anaérobies et du Botulisme, Institut Pasteur, France.
authors: Philippe
authors: P
authors: Bouvet
authors: Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Nice, France.
authors: Nicolas
authors: N
authors: Degand
authors: Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Nice, France.
authors: Antonin
authors: A
authors: Bal
authors: Université de Nice Côte d'Azur, Inserm, C3M, Nice, France; Service d'anesthésie Réanimation, Centre Hospitalier Universitaire de Nice, Nice, France.
authors: Michel
authors: M
authors: Carles
authors: Service de Traumatologie, Centre Hospitalier Universitaire de Nice, Nice, France.
authors: Regis Bernard
authors: RB
authors: de Dompsure
authors: Centre de Reference des Bactéries Anaérobies et du Botulisme, Institut Pasteur, France.
authors: Michel-Robert
authors: MR
authors: Popoff
authors: Laboratoire de Bactériologie, Centre Hospitalier Universitaire de Nice, Nice, France; Université de Nice Côte d'Azur, Inserm, C3M, Nice, France; Inserm U1065, C3M, Team6: "Bacterial Toxins in Host Pathogen Interactions", Bâtiment Universitaire Archimed, Nice, France.
authors: Raymond
authors: R
authors: Ruimy
mesh_terms: D000328:Adult; D000693:Anaerobiosis; D000900:Anti-Bacterial Agents / Q000627:therapeutic use; D001426:Bacterial Proteins / Q000235:genetics* / Q000378:metabolism; D002908:Chronic Disease; D003013:Clostridium / Q000145:classification / Q000187:drug effects / Q000235:genetics / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D057075:Enzyme Assays; D005260:Female; D050723:Fractures, Bone / Q000150:complications / Q000175:diagnosis / Q000382:microbiology; D015870:Gene Expression; D006801:Humans; D008826:Microbial Sensitivity Tests; D010000:Osteitis / Q000175:diagnosis* / Q000188:drug therapy / Q000209:etiology / Q000382:microbiology; D010802:Phylogeny; D012336:RNA, Ribosomal, 16S / Q000235:genetics* / Q000378:metabolism; D019032:Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
chemical_list: D000900:Anti-Bacterial Agents; D001426:Bacterial Proteins; D012336:RNA, Ribosomal, 16S
keywords: Clostridium; Emerging pathogen; Osteitis