title: Fluorescein photodiagnosis of idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome: A case report and long-term outcome of photocoagulation therapy.
abstract: Idiopathic retinal vasculitis, aneurysms, and neuroretinitis (IRVAN) syndrome is a disease characterized by multiple retinal macroaneurysms, neuroretinitis and peripheral capillary non-perfusion, leading to irreversible visual loss. It includes five stages and has previously been rarely reported. IRVAN syndrome is especially rare in Asia. In this report, we describe laser diagnosis and therapy in an Asian patient with IRVAN syndrome over two years of follow-up. We observed non-perfusion retina and dilated retinal capillaries in the contralateral eye. Photocoagulation is an effective therapy to control retinal macroaneurysms and nonperfusions and to prevent visual loss, particularly in the early stages of IRVAN syndrome (stages 2 & 3). To the best of our knowledge, this is the first long-term observation of photocoagulation in IRVAN syndrome. We discovered the early signs of such lesions, which may be beneficial for clinical diagnosis and therapy.
authors: Department of Radiology, First Affiliated Hospital of China Medical University, Key Laboratory of Diagnostic Imaging and Interventional Radiology, Shenyang, China.
authors: Yonghui
authors: Y
authors: Xia
authors: Ophthalmology Center, Renmin Hospital of Wuhan University, Wuhan, China.
authors: Yu
authors: Y
authors: Su
authors: Department of Ophthalmology, University of Hong Kong, Hong Kong, China.
authors: Ian Hin Yat
authors: IH
authors: Wong
authors: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, China. Electronic address: xiaolimax2015@sina.com.
authors: Xiaoli
authors: X
authors: Ma
authors: Department of Ophthalmology, First Hospital of China Medical University, Shenyang, China. Electronic address: woodshua@126.com.
authors: Rui
authors: R
authors: Hua
mesh_terms: D000783:Aneurysm / Q000175:diagnosis / Q000628:therapy*; D005260:Female; D005451:Fluorescein Angiography / Q000379:methods*; D006801:Humans; D008028:Light Coagulation / Q000379:methods*; D008137:Longitudinal Studies; D008875:Middle Aged; D031300:Retinal Vasculitis / Q000175:diagnosis* / Q000628:therapy*; D012173:Retinitis / Q000175:diagnosis* / Q000628:therapy*; D013577:Syndrome; D016896:Treatment Outcome
keywords: Fluorescein angiography; IRVAN syndrome; Non-perfusion retina; Retinal photocoagulation