title: Histiocytic chorioretinitis in a dog.
abstract: A 3-year-old castrated male mixed-breed dog presented with an acute bullous retinal detachment and thickened choroid of the right eye. Subretinal cytology revealed an atypical cell proliferation suggestive of neoplasia. The eye was enucleated, and the original diagnosis was a histologically benign choroidal melanocytic tumor. Further diagnostics revealed no other systemic abnormalities other than a nonhealing shoulder wound. Six months later, the left eye developed a bullous retinal detachment. This eye responded well to systemic steroids and the dog regained vision within a few weeks of initiating therapy. Results of immunohistochemistry with Melan-A and CD204 of the previously enucleated right eye caused a revision of the histologic diagnosis from melanocytic tumor to histiocytic chorioretinitis. This case highlights the subtle and sometimes confusing distinction between neoplastic and inflammatory processes on both cytology and histopathology.
authors: Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.
authors: Amanda B
authors: AB
authors: Sherman
authors: Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.
authors: John M
authors: JM
authors: Cullen
authors: Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.
authors: Hans D
authors: HD
authors: Westermeyer
authors: Department of Population Health and Pathobiology, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.
authors: Carol
authors: C
authors: Grindem
authors: Department of Clinical Sciences, North Carolina State University College of Veterinary Medicine, Raleigh, NC, USA.
authors: Brian C
authors: BC
authors: Gilger
mesh_terms: D000818:Animals; D002825:Chorioretinitis / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D003941:Diagnostic Techniques, Ophthalmological; D004283:Dog Diseases / Q000175:diagnosis*; D004285:Dogs; D015353:Eye Enucleation; D008297:Male
keywords: Melan-A; canine; chorioretinitis; histiocytic; melanoma; retinal detachment