title: Limbic Encephalitis Associated with Sjögren's Syndrome: Report of Three Cases.
abstract: Sjögren's syndrome (SS) may be complicated by neurological manifestations. We herein report three women (age range 26-60 years old) who all presented with limbic encephalitis (LE) as the predominant clinical feature 3 months to 15 years after the diagnosis of SS. The 26-year-old patient also developed acute motor axonal neuropathy one week after autoimmune encephalitis. All three patients showed contrast-enhanced MRI lesions and inflammatory cerebrospinal fluid findings, while not displaying any anti-neuronal antibodies and showing a remarkable response to immunotherapy. SS is often overlooked when the symptoms are mild. Therefore, in LE cases with no identifiable cause, serological screening for rheumatologic disorders is recommended.
authors: Department of Neurology, Istanbul Faculty of Medicine, Istanbul University, Turkey.
authors: Arzu
authors: A
authors: Çoban
authors: Selen
authors: S
authors: Özyurt
authors: Kaan
authors: K
authors: Meriç
authors: Handan
authors: H
authors: Mısırlı
authors: Erdem
authors: E
authors: Tüzün
authors: Recai
authors: R
authors: Türkoğlu
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000134:cerebrospinal fluid; D001927:Brain Diseases / Q000150:complications; D005260:Female; D006801:Humans; D020363:Limbic Encephalitis / Q000134:cerebrospinal fluid* / Q000150:complications / Q000000981:diagnostic imaging*; D008279:Magnetic Resonance Imaging; D008875:Middle Aged; D012859:Sjogren's Syndrome / Q000134:cerebrospinal fluid* / Q000150:complications / Q000000981:diagnostic imaging*
chemical_list: D015415:Biomarkers