title: [Possibilities of treatment optimization in children and adolescents with epilepsy and disturbances of emotion and volition (disphoria)].
abstract: OBJECTIVE
  To optimize the treatment of dysphoriain children and adolescents in regard to sex and disease severity.
  
  
  METHODS
  Seventy children and adolescents (boys - 45, girls - 25), aged from 6 to 18 years, with different forms of epilepsy and emotion and dysphoric disturbances were studied using CPRS andGCIscales Depending on dysphoria severity, patients were stratified into three groups: mild (n=19 (27.1%), moderate (n=27 (38.6%)) and severe (n=24 (34.3%)).
  
  
  CONCLUSIONS
  Dysphoric disorders were significantly more prevalent in boys, hostility and aggression were characteristic of boys as well. These facts impactedtreatment options. Neuroleptics were more frequently used in boys (35.5%) compared to girls(16%).Mild dysphoria didn't require additional treatment besides AED in 78,4%. In 75% cases of moderate dysphoria,systemic treatment with neuroleptics for 6 months was necessary. One-time recommendations for neuroleptic treatment were made in all three groups with the prevalence in a groupof children with severe and moderate dysphoria.
authors: Bekhterev St. Petersburg Research Psychoneurological Institute, St. Petersburg, Russia.
authors: Yu V
authors: YV
authors: Popov
authors: Bekhterev St. Petersburg Research Psychoneurological Institute, St. Petersburg, Russia.
authors: Yu A
authors: YA
authors: Yakovleva
authors: Bekhterev St. Petersburg Research Psychoneurological Institute, St. Petersburg, Russia.
authors: S V
authors: SV
authors: Semenova
mesh_terms: D000293:Adolescent; D000342:Affective Symptoms / Q000188:drug therapy* / Q000209:etiology; D000374:Aggression; D000927:Anticonvulsants / Q000627:therapeutic use*; D014150:Antipsychotic Agents / Q000627:therapeutic use*; D002648:Child; D004827:Epilepsy / Q000150:complications / Q000188:drug therapy* / Q000523:psychology*; D005260:Female; D006801:Humans; D008297:Male; D014836:Volition
chemical_list: D000927:Anticonvulsants; D014150:Antipsychotic Agents