title: Elevated Nucleated Red Blood Cells at Birth Predict Hemodynamically Significant Patent Ductus Arteriosus.
abstract: We hypothesized that postnatal absolute nucleated red blood cell (aNRBC) counts would be elevated in premature infants with hemodynamically significant patent ductus arteriosus (PDA), reflecting intrauterine hypoxia. PDA severity was assessed and categorized echocardiographically. aNRBC counts were significantly correlated with ductal severity (Pearson correlation: P = .007). At the extremes, aNRBC levels were 3770 (728, 6015) hemodynamically significant PDA vs 865 (483, 2528) closed ductus.
authors: Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel. Electronic address: alona.binnun@gmail.com.
authors: Alona
authors: A
authors: Bin-Nun
authors: Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
authors: Francis B
authors: FB
authors: Mimouni
authors: Department of Pediatric Cardiology, Shaare Zedek Medical Center, Jerusalem, Israel.
authors: Daniel
authors: D
authors: Fink
authors: Department of Obstetrics & Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel.
authors: Hen
authors: H
authors: Sela
authors: Department of Neonatology, Shaare Zedek Medical Center, Jerusalem, Israel; Faculty of Medicine, Hebrew University, Jerusalem, Israel.
authors: Cathy
authors: C
authors: Hammerman
mesh_terms: D004374:Ductus Arteriosus, Patent / Q000097:blood* / Q000503:physiopathology*; D004906:Erythrocyte Count; D004913:Erythrocytes, Abnormal; D006439:Hemodynamics; D006801:Humans; D007231:Infant, Newborn; D011237:Predictive Value of Tests; D011446:Prospective Studies
keywords: nucleated red blood cells; patent ductus arteriosus; premature neonate