title: Using the dendritic polymer PAMAM to form gold nanoparticles in the protein cage thermosome.
abstract: The chaperonin thermosome (THS) is a protein cage that lacks binding sites for metal ions and inorganic nanoparticles. However, when poly(amidoamine) (PAMAM) is encapsulated into THS, gold nanoparticles (AuNP) can be prepared in the THS. The polymer binds HAuCl4. Subsequent reduction yields nanoparticles with narrow size distribution in the protein-polymer conjugate.
authors: Department of Chemistry, University of Basel, Klingelbergstrasse 80, 4056 Basel, Switzerland and Wyss Institute for Biologically Inspired Engineering, Harvard University, Cambridge, Massachusetts 02138, USA.
authors: Martin G
authors: MG
authors: Nussbaumer
authors: Department of Chemistry, University of Basel, Klingelbergstrasse 80, 4056 Basel, Switzerland and Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland. nico.bruns@unifr.ch.
authors: Christoph
authors: C
authors: Bisig
authors: Department of Chemistry, University of Basel, Klingelbergstrasse 80, 4056 Basel, Switzerland and Adolphe Merkle Institute, University of Fribourg, Chemin des Verdiers 4, 1700 Fribourg, Switzerland. nico.bruns@unifr.ch.
authors: Nico
authors: N
authors: Bruns
mesh_terms: D002712:Chlorides / Q000737:chemistry*; D050091:Dendrimers / Q000737:chemistry*; D006046:Gold / Q000737:chemistry*; D017612:Gold Compounds / Q000737:chemistry*; D053768:Metal Nanoparticles / Q000737:chemistry*; D010316:Particle Size; D011073:Polyamines / Q000737:chemistry*; D013822:Thermoplasma; D056405:Thermosomes / Q000737:chemistry*
chemical_list: D002712:Chlorides; D050091:Dendrimers; D017612:Gold Compounds; C104700:PAMAM Starburst; C531249:Poly(amidoamine); D011073:Polyamines; D006046:Gold; C024568:gold tetrachloride, acid; D056405:Thermosomes