title: Functionally Assessing Candidate Drivers Advances Precision Cancer Medicine.
abstract: The complexity of genomic alterations in cancer has made it difficult to identify oncogenic drivers for the development of targeted therapies. The study by Berger et al. in this issue of Cancer Cell demonstrates that high-throughput functional profiling can uncover impactful mutations and oncogenic driver alleles.
authors: Department of Molecular and Human Genetics, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA.
authors: Kenneth L
authors: KL
authors: Scott
authors: Department of Pathology, Stony Brook University, One Nichols Drive, Stony Brook, NY 11794, USA. Electronic address: scott.powers@stonybrook.edu.
authors: Scott
authors: S
authors: Powers
mesh_terms: D023281:Genomics; D006801:Humans; D009154:Mutation; D009369:Neoplasms; D057285:Precision Medicine