title: Sleep Outcomes in Children With Single-Suture Craniosynostosis Compared With Unaffected Controls.
abstract: To compare risk for sleep-disordered breathing between children with and without single-suture craniosynostosis.
  
  
  
  A total of 184 children with single-suture craniosynostosis and 184 controls.
  
  
  
  Parent reported sleep-disordered breathing-related symptoms.
  
  
  
  Current sleep problems were reported in 19% of patients with single-suture craniosynostosis and 14% of controls (adjusted odds ratio = 1.6; 95% CI, 0.9 to 2.8). Ever having sleep problems was reported in 25% and 23% of cases and controls, respectively (adjusted odds ratio = 1.2; 95% CI, 0.7 to 1.9). Overall, snoring was statistically associated with single-suture craniosynostosis (P = .01) and was more often reported as 2+ nights per week (versus never) in patients with single-suture craniosynostosis (13%) than in controls (4%) (adjusted odds ratio = 3.5; 95% CI, 1.5 to 8.2).
  
  
  
  Though preliminary, increased presence of snoring during sleep in children with single-suture craniosynostosis compared with controls suggests that children with isolated single-suture craniosynostosis may be at increased risk for sleep-disordered breathing. Further study using standardized assessments of sleep-disordered breathing is needed.
authors: Baiyang
authors: B
authors: Sun
authors: Yona K
authors: YK
authors: Cloonan
authors: Brent R
authors: BR
authors: Collett
authors: Matthew L
authors: ML
authors: Speltz
mesh_terms: D002648:Child; D003398:Craniosynostoses / Q000150:complications*; D003430:Cross-Sectional Studies; D005260:Female; D005500:Follow-Up Studies; D006801:Humans; D007407:Interviews as Topic; D008297:Male; D012891:Sleep Apnea Syndromes / Q000209:etiology*; D012959:Socioeconomic Factors
keywords: craniofacial abnormalities; craniosynostoses; sleep apnea syndromes; sleep disorders;  child