title: Effect of incorporating seed oils on the antifungal property, surface roughness, wettability, weight change, and glucose sorption of a soft liner.
abstract: BACKGROUND
  The colonization of Candida albicans on soft liners causes the deterioration of material surface properties and denture stomatitis.
  
  
  OBJECTIVE
  The purpose of this in vitro study was to investigate the effect of incorporating seed oil on the antifungal properties, surface roughness, wettability, weight changes, and glucose adsorption/absorption of a soft liner.
  
  
  METHODS
  Centratherum anthelminticum, Ocimum sanctum Linn, and Linum usitatissimum seed oils were incorporated into a soft liner, and the diameter of the inhibition zone (DIZ) was calculated relative to the growth of C albicans at 24, 48, and 72 hours and 7 days. The effect of incorporating oil on wettability was evaluated with the contact angle analyzer, and effect on surface roughness was evaluated with scanning electron microscopy. Weight changes and absorption/adsorption of glucose to the soft liner were estimated. Data were analyzed by using paired Student t tests and 2-way ANOVA (α=.01).
  
  
  RESULTS
  Soft liner with 800 μL each of C anthelminticum and O sanctum oils showed complete inhibition at 72 hours; the DIZ on day 7 were 31.66 ±1.20 mm and 29.66 ±1.46 mm, respectively. The change in weight between time intervals differed significantly between conditions (P<.01). The addition of oils decreased the surface roughness and improved wettability significantly for O sanctum and C anthelminticum specimens (P<.01). At 72 hours, 5.5 mg of glucose was detected in the positive control, whereas no glucose was detected in the oil specimens.
  
  
  CONCLUSIONS
  The addition of the seed oils of C anthelminticum and O sanctum to the soft liner significantly reduced the growth of C albicans, improved wettability, reduced surface roughness, and minimized the absorption and adsorption of glucose.
authors: Professor, Department of Biochemistry, Coorg Institute of Dental Sciences, Virajpet, Coorg, and Rajiv Gandhi University of Health Sciences, Bangalore, India. Electronic address: seshim2000@gmail.com.
authors: Seshagiri
authors: S
authors: Muttagi
authors: Professor, Department of Prosthodontics and Crown and Bridge and Implantology, Coorg Institute of Dental Sciences, Virajpet, Coorg, and Rajiv Gandhi University of Health Sciences, Bangalore, India.
authors: Jyothi Keralapura
authors: JK
authors: Subramanya
mesh_terms: D000935:Antifungal Agents / Q000627:therapeutic use*; D002176:Candida albicans / Q000187:drug effects / Q000254:growth & development; D003822:Denture Liners / Q000382:microbiology / Q000592:standards; D019597:Flax / Q000737:chemistry; D005947:Glucose; D008855:Microscopy, Electron, Scanning; D010938:Plant Oils / Q000627:therapeutic use*; D012639:Seeds / Q000737:chemistry*; D013499:Surface Properties; D017155:Wettability / Q000187:drug effects
chemical_list: D000935:Antifungal Agents; D010938:Plant Oils; C080118:ocimum oil; D005947:Glucose