title: Synthesis of a series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives as potential antioxidant and antibacterial agents.
abstract: A series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and screened for their antimicrobial and antioxidant activities. The assay indicated that compounds 3c, 3d, and 3i exhibited comparable antibacterial and antioxidant activity with first-line drugs. The structure activity relationship and molecular docking study of the synthesized compounds are also reported.
authors: Department of P.G. Studies and Research in Industrial Chemistry, Jnana Sahyadri, Kuvempu University, Shankaraghatta, 577451 Shivamogga, Karnataka India.
authors: M Aruna
authors: MA
authors: Sindhe
authors: Department of P.G. Studies and Research in Industrial Chemistry, Jnana Sahyadri, Kuvempu University, Shankaraghatta, 577451 Shivamogga, Karnataka India.
authors: Yadav D
authors: YD
authors: Bodke
authors: Department of P.G. Studies and Research in Industrial Chemistry, Jnana Sahyadri, Kuvempu University, Shankaraghatta, 577451 Shivamogga, Karnataka India.
authors: R
authors: R
authors: Kenchappa
authors: Department of P.G. Studies and Research in Biotechnology, Jnana Sahyadri, Kuvempu University, Shankaraghatta, 577451 Shivamogga, Karnataka India.
authors: Sandeep
authors: S
authors: Telkar
authors: Department of P.G. Studies and Research in Industrial Chemistry, Jnana Sahyadri, Kuvempu University, Shankaraghatta, 577451 Shivamogga, Karnataka India.
authors: A
authors: A
authors: Chandrashekar
keywords: 1,3,4-Oxadiazole; Antimicrobial; Antioxidant; Molecular docking