title: Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans.
abstract: We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56(dim) NK cell responses to a variety of stimuli and with CD56(bright)/CD56(dim) NK cell ratio. We also present the correlation of retinol binding protein (RBP)-4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56(dim) NK cell responses. These data are discussed in Al-Attar et al. (2016) [1].
authors: Department of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.
authors: Ahmad
authors: A
authors: Al-Attar
authors: Department of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA.
authors: Steven R
authors: SR
authors: Presnell
authors: Department of Rehabilitation Sciences, College of Health Sciences, University of Kentucky, Lexington, KY, USA.
authors: Charlotte A
authors: CA
authors: Peterson
authors: Department of Clinical Sciences, College of Health Sciences, University of Kentucky, Lexington, KY, USA.
authors: D Travis
authors: DT
authors: Thomas
authors: Department of Pathology and Laboratory Medicine, College of Medicine, University of Kentucky, Lexington, KY, USA; Department of Microbiology, Immunology and Molecular Genetics, College of Medicine, University of Kentucky, Lexington, KY, USA.
authors: Charles T
authors: CT
authors: Lutz
keywords: Adiponectin; Ageing; C-reactive protein; Cytomegalovirus; IL-15; NK cell; Retinol binding protein-4; Sex factors; Sphingosine-1-phosphate; T cell; Vitamin D