title: Burkitt Lymphoma Preceded by Autoimmune Hemolytic Anemia due to Anti-D Antibody.
abstract: We herein report a rare case of Burkitt lymphoma (BL) preceded by autoimmune hemolytic anemia (AIHA) caused by autoantibodies against D antigen. After a partial response to AIHA with prednisolone (PSL) treatment for 7 months, the patient developed BL with a t(8;22)(q24;q11.2) chromosomal translocation. Intensive immunochemotherapy, including rituximab, led to a complete response (CR) of BL; however, anti-D antibody remained detectable in the plasma and antibody-dissociated solution from erythrocytes, thus continuous therapy with PSL was necessary even after achievement of the CR. BL with AIHA is extremely rare, with only one previously reported case in the literature.
authors: Division of Hematology and Oncology, Department of Medicine, Kyoto Prefectural University of Medicine, Japan.
authors: Yoshimi
authors: Y
authors: Mizuno
authors: Yuji
authors: Y
authors: Shimura
authors: Shigeo
authors: S
authors: Horiike
authors: Tomoko
authors: T
authors: Takimoto
authors: Saori
authors: S
authors: Maegawa
authors: Kazuna
authors: K
authors: Tanba
authors: Yayoi
authors: Y
authors: Matsumura-Kimoto
authors: Yukari
authors: Y
authors: Sumida
authors: Shotaro
authors: S
authors: Tatekawa
authors: Taku
authors: T
authors: Tsukamoto
authors: Yoshiaki
authors: Y
authors: Chinen
authors: Shinsuke
authors: S
authors: Mizutani
authors: Hisao
authors: H
authors: Nagoshi
authors: Mio
authors: M
authors: Yamamoto-Sugitani
authors: Yosuke
authors: Y
authors: Matsumoto
authors: Tsutomu
authors: T
authors: Kobayashi
authors: Junya
authors: J
authors: Kuroda
authors: Masafumi
authors: M
authors: Taniwaki
mesh_terms: D000368:Aged; D000744:Anemia, Hemolytic, Autoimmune / Q000000981:diagnostic imaging* / Q000188:drug therapy; D002051:Burkitt Lymphoma / Q000097:blood* / Q000150:complications; D005260:Female; D006801:Humans; D011239:Prednisolone / Q000627:therapeutic use; D018029:Rho(D) Immune Globulin / Q000097:blood*
chemical_list: C061961:RHO(D) antibody; D018029:Rho(D) Immune Globulin; D011239:Prednisolone