title: Local cause of gingival overgrowth. Clinical and histological study.
abstract: The overgrowth, depending on its extension, has multiple effects on the stomatognathic apparatus: functional disorders (impaired speech), difficulty in chewing and aesthetic problems but can cause significant psychological problems. We proposed this study, motivated by the relative increased frequency of the gum outgrowth, its multifactorial etiopathogeny, but especially from the point of view of the specialist practitioner, by the problems that this pathology raises not only for the functionality of the stomatognathic apparatus but also for the facial esthetics, and especially for future therapeutic attitudes needed to solve the existing pathology at this level. We conducted a clinical study and a histological one. For the clinical study, we selected 74 patients who experienced different degrees of gingival outgrowing associated with fillings, dental caries, fixed prostheses, mobile prostheses, orthodontic apparatus. Thirty gingival fragments from patients with gingival outgrowing were processed by paraffin-embedding histological technique and stained with Hematoxylin-Eosin. The morphological results obtained provide the necessary support for understanding the possibility of developing a therapeutic strategy to prevent or minimize the gum outgrowth by administering antibiotic and anti-inflammatory medications associated with medications, which shall cause the apoptosis of the fibroblasts.
authors: Department of Histology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania; scraitoiu@yahoo.com.
authors: Emma Cristina
authors: EC
authors: Drăghici
authors: Ştefania
authors: Ş
authors: CrăiŢoiu
authors: Veronica
authors: V
authors: MercuŢ
authors: Monica
authors: M
authors: Scrieciu
authors: Sanda Mihaela
authors: SM
authors: Popescu
authors: Oana Andreea
authors: OA
authors: Diaconu
authors: Bogdan
authors: B
authors: Oprea
authors: Roxana Maria
authors: RM
authors: Pascu
authors: Monica Mihaela
authors: MM
authors: CrăiŢoiu
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D004848:Epithelium / Q000473:pathology; D005260:Female; D019214:Gingival Overgrowth / Q000209:etiology* / Q000473:pathology*; D006801:Humans; D007249:Inflammation / Q000473:pathology; D008297:Male; D009910:Oral Hygiene; D055815:Young Adult