title: 2014 Revised Classification of Vascular Lesions from the International Society for the Study of Vascular Anomalies: Radiologic-Pathologic Update.
abstract: Since the publication of the seminal work on the histology-based classification of vascular anomalies by Mulliken and Glowacki in 1982 and the subsequent adoption of an expanded and modified version in 1996 by the International Society for the Study of Vascular Anomalies, an increasing number of vascular lesions have been recognized as histologically distinct entities. Furthermore, there have been significant advances in detailing the behavior and underlying genetics of previously identified lesions. These developments have required restructuring and expansion of the classification scheme so that appropriate therapies may be studied and implemented in affected patients. The new classification retains the broad categories of neoplasms and malformations but now divides the tumor group into benign, locally aggressive or borderline, and malignant, with the malformation group being divided into simple, combined, those of major named vessels, and those associated with other anomalies. Additionally, a category has been created for lesions in which the histology and behavior do not yet allow clear separation into neoplasm or malformation (thus named "provisionally unclassified vascular anomalies"). The known clinical courses and imaging, histologic, and genetic findings of the most common and/or clinically relevant lesions in the newly adopted revised system are reviewed in this article. (©)RSNA, 2016.
authors: From the Department of Radiology (A.C.M., M.N.P.) and Department of Pediatrics, Division of Pathology and Laboratory Medicine (A.G.), Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH 45229; and Vascular Anomalies Center, Boston Children's Hospital, Boston, Mass (D.M.A.).
authors: Arnold C
authors: AC
authors: Merrow
authors: From the Department of Radiology (A.C.M., M.N.P.) and Department of Pediatrics, Division of Pathology and Laboratory Medicine (A.G.), Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH 45229; and Vascular Anomalies Center, Boston Children's Hospital, Boston, Mass (D.M.A.).
authors: Anita
authors: A
authors: Gupta
authors: From the Department of Radiology (A.C.M., M.N.P.) and Department of Pediatrics, Division of Pathology and Laboratory Medicine (A.G.), Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH 45229; and Vascular Anomalies Center, Boston Children's Hospital, Boston, Mass (D.M.A.).
authors: Manish N
authors: MN
authors: Patel
authors: From the Department of Radiology (A.C.M., M.N.P.) and Department of Pediatrics, Division of Pathology and Laboratory Medicine (A.G.), Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH 45229; and Vascular Anomalies Center, Boston Children's Hospital, Boston, Mass (D.M.A.).
authors: Denise M
authors: DM
authors: Adams
mesh_terms: D003937:Diagnosis, Differential; D003952:Diagnostic Imaging / Q000379:methods*; D006801:Humans; D054079:Vascular Malformations / Q000145:classification* / Q000000981:diagnostic imaging*; D019043:Vascular Neoplasms / Q000145:classification* / Q000000981:diagnostic imaging*