title: Prognostic value of 18F-FDG PET/CT for identifying high- and low-risk endometrial cancer patients.
abstract: To assess the usefulness of adding PET/CT as a preoperative test for determining the extent of endometrial cancer and discriminating low- and high-risk patients to identify candidates for surgical staging.
  
  
  
  We retrospectively reviewed 86 patients with pathologically proven endometrial cancer who had undergone preoperative ¹⁸F-FDG PET/CT. The prognostic relationships between PET/CT parameters and pathology reports were assessed.
  
  
  
  The SUVmax was significantly higher in patients with FIGO stage IB or higher compared with those with stage IA; for stage III-IV compared with stage I-II; and for patients with lymph node metastasis compared with those without lymph node metastasis. Using 6.70 as a cut-off for SUVmax, low-risk patients can be identified with a sensitivity of 92.9%.
  
  
  
  PET/CT imaging can be used not only for determining malignancy and lymph node involvement but also for determining candidates for surgical staging with high sensitivity.
authors: Zekai Tahir Burak Women Health Education and Research Hospital, Gynecologic Oncology Department, Ankara, Turkey. emreozgu@hotmail.com.
authors: Emre
authors: E
authors: Özgü
authors: Murat
authors: M
authors: Öz
authors: Yunus
authors: Y
authors: Yıldız
authors: Burçin Salman
authors: BS
authors: Özgü
authors: Salim
authors: S
authors: Erkaya
authors: Tayfun
authors: T
authors: Güngör
mesh_terms: D000328:Adult; D000368:Aged; D016889:Endometrial Neoplasms / Q000175:diagnosis / Q000473:pathology; D005260:Female; D019788:Fluorodeoxyglucose F18 / Q000494:pharmacology*; D006801:Humans; D008207:Lymphatic Metastasis / Q000000981:diagnostic imaging* / Q000473:pathology; D008875:Middle Aged; D009367:Neoplasm Staging; D000072078:Positron Emission Tomography Computed Tomography / Q000379:methods*; D011237:Predictive Value of Tests; D011379:Prognosis; D019275:Radiopharmaceuticals / Q000494:pharmacology; D012189:Retrospective Studies; D018570:Risk Assessment / Q000379:methods; D014421:Turkey
chemical_list: D019275:Radiopharmaceuticals; D019788:Fluorodeoxyglucose F18
keywords: PET/CT; SUVmax; endometrial cancer; prognosis