title: Prevalence and Factors Associated With Statin Use Among a Nationally Representative Sample of US Adults: National Health and Nutrition Examination Survey, 2011-2012.
abstract: The 2013 American College of Cardiology/American Heart Association guidelines recommend statins for adults age ≤75 years who have clinical atherosclerotic cardiovascular disease (IA) and adults age 40 to 75 years with diabetes mellitus and LDL-C 70-189 mg/dl (IA). Our aim was to estimate the prevalence and likelihood of statin use among selected statin benefit groups. Using data from the National Health and Nutrition Examination Survey (NHANES) 2011-2012, we examined 5319 adults age ≥20 years. We estimated weighted frequencies and prevalence of statin use for adults with diabetes mellitus and dyslipidemia (or low-density lipoprotein cholesterol ≥70 mg/dL), defined as statin benefit group 1 (SBG1); and for adults with atherosclerotic cardiovascular disease, defined as statin benefit group 2 (SBG2). We constructed a logistic regression model to estimate odds of statin use in SBG1. Overall, an estimated 38.6 million Americans are on a statin. In adjusted models, uninsured and Hispanic adults were less likely to be on a statin compared with white adults; 59.5% (95% confidence interval [CI]: 53.0-66.1) of all adults in SBG1, 58.8% (95% CI: 51.5-66.1) of adults age 40 to 75 in SBG1, and 63.5% (95% CI: 55.6-71.4) of all adults in SBG2 were on a statin. Although the prevalence of statin use has increased over time, Hispanic ethnicity and lack of insurance remain barriers to statin use. Black-white racial disparities were not significant. Our study provides a baseline estimate of statin use in the noninstitutionalized population just prior to introduction of the new guidelines and provides a reference for evaluating the impact of the new guidelines on statin utilization.
authors: Division of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia. dadedinsewo@msm.edu.|Grady Memorial Hospital, Atlanta, Georgia. dadedinsewo@msm.edu.
authors: Demilade
authors: http://orcid.org/0000-0002-8629-2029
authors: D
authors: Adedinsewo
authors: Division of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.|Grady Memorial Hospital, Atlanta, Georgia.
authors: Nchang
authors: N
authors: Taka
authors: Division of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.|Grady Memorial Hospital, Atlanta, Georgia.
authors: Pradyumna
authors: P
authors: Agasthi
authors: Division of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.|Grady Memorial Hospital, Atlanta, Georgia.
authors: Rajesh
authors: R
authors: Sachdeva
authors: Department of Behavioral Sciences and Social Medicine, Florida State University College of Medicine, Tallahassee, Florida.
authors: George
authors: G
authors: Rust
authors: Division of Cardiology, Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia.|Grady Memorial Hospital, Atlanta, Georgia.
authors: Anekwe
authors: A
authors: Onwuanyi
mesh_terms: D000328:Adult; D001741:Black or African American; D000367:Age Factors; D000368:Aged; D050197:Atherosclerosis / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000208:ethnology; D016009:Chi-Square Distribution; D015897:Comorbidity; D003920:Diabetes Mellitus / Q000208:ethnology; D050171:Dyslipidemias / Q000097:blood / Q000175:diagnosis / Q000188:drug therapy* / Q000208:ethnology; D005260:Female; D054625:Healthcare Disparities / Q000208:ethnology; D006630:Hispanic or Latino; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D016015:Logistic Models; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D009749:Nutrition Surveys; D016017:Odds Ratio; D017410:Practice Guidelines as Topic; D015995:Prevalence; D012307:Risk Factors; D013997:Time Factors; D014481:United States / Q000453:epidemiology; D044465:White People; D055815:Young Adult
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: Clinical; Epidemiology; Lipidology; Pharmacology; Preventive cardiology