title: [Constipation in Patients with Incurable Cancer - Recommendations of the German S3 Guideline 'Palliative Medicine'].
abstract: According to the German S3-guideline 'Palliative Medicine' which has been supported by the German Guideline Program in Oncology, constipation in palliative patients requires a consistent prophylaxis and therapy. Constipation is caused by immobilisation, poor health, exsiccosis, a low-fiber diet or a preexisting functional constipation. Further important causes are substances with constipating side effects, such as opioids or anticholinergic drugs. Pragmatically, constipation should be assessed by subjective parameters such as the feeling of incomplete evacuation, straining, or other complaints. Objective parameters are hard stool or reduced number of bowel movements. For the early detection of constipation the amount of the stool mass and the stool frequency are applicable. If constipation occurs, a standardized escalating protocol applying adequate fluid intake, a high fibre diet, and laxatives is recommended. New prokinetic agents, secretagogues, or opioid antagonists may be used as reserve drugs.
authors: Stefan
authors: S
authors: Wirz
authors: Steffen
authors: S
authors: Simon
authors: Thomas
authors: T
authors: Frieling
authors: Claudia
authors: C
authors: Bausewein
authors: Raymond
authors: R
authors: Voltz
authors: Anne
authors: A
authors: Pralong
authors: Stefan
authors: S
authors: Mönig
authors: Markus
authors: M
authors: Follmann
authors: Martin
authors: M
authors: Holtmann
authors: Gerhild
authors: G
authors: Becker
mesh_terms: D003248:Constipation / Q000150:complications / Q000175:diagnosis / Q000517:prevention & control / Q000628:therapy; D006801:Humans; D009369:Neoplasms / Q000150:complications*; D065126:Palliative Medicine / Q000379:methods*