title: Visceral leishmaniasis in a rheumatoid arthritis patient receiving methotrexate.
abstract: Patients with rheumatoid arthritis (RA) treated with disease-modifying antirheumatic drugs are susceptible to severe infections such as leishmaniasis. As L. infantum is endemic in the Mediterranean region, it is necessary to rule this infectious process out in any RA patient presenting with fever and pancytopenia. An early diagnosis based on a high suspicion can prevent a fatal outcome.
authors: Servicio de Reumatología, Hospital Moisès Broggi, Consorci Sanitari Integral, Sant Joan Despí, Barcelona, España. Electronic address: deliareinasanz@gmail.com.
authors: Delia
authors: D
authors: Reina
authors: Servicio de Reumatología, Hospital Moisès Broggi, Consorci Sanitari Integral, Sant Joan Despí, Barcelona, España.
authors: Dacia
authors: D
authors: Cerdà
authors: Servicio de Medicina Interna, Hospital de Barcelona, Barcelona, España.
authors: Elena
authors: E
authors: Güell
authors: Servicio de Medicina Interna, Hospital de Barcelona, Barcelona, España.
authors: Joaquín
authors: J
authors: Martínez Montauti
authors: Servicio de Hematología, Hospital de Barcelona, Barcelona, España.
authors: Antonio
authors: A
authors: Pineda
authors: Servicio de Reumatología, Hospital Moisès Broggi, Consorci Sanitari Integral, Sant Joan Despí, Barcelona, España.
authors: Hèctor
authors: H
authors: Corominas
mesh_terms: D000666:Amphotericin B / Q000627:therapeutic use; D000981:Antiprotozoal Agents / Q000627:therapeutic use; D001172:Arthritis, Rheumatoid / Q000150:complications* / Q000188:drug therapy; D004198:Disease Susceptibility; D042241:Early Diagnosis; D005260:Female; D006801:Humans; D016867:Immunocompromised Host; D007166:Immunosuppressive Agents / Q000009:adverse effects* / Q000627:therapeutic use; D007213:Indomethacin / Q000627:therapeutic use; D007898:Leishmaniasis, Visceral / Q000175:diagnosis / Q000188:drug therapy / Q000209:etiology*; D008727:Methotrexate / Q000009:adverse effects* / Q000627:therapeutic use; D008875:Middle Aged; D010198:Pancytopenia / Q000139:chemically induced; D011241:Prednisone / Q000009:adverse effects / Q000627:therapeutic use
chemical_list: D000981:Antiprotozoal Agents; D007166:Immunosuppressive Agents; C068538:liposomal amphotericin B; D000666:Amphotericin B; D011241:Prednisone; D007213:Indomethacin; D008727:Methotrexate
keywords: Artritis reumatoide; Kala-azar; Methotrexate; Metotrexato; Rheumatoid arthritis