title: Copper(I) halide complexes of 2,2,5,5-tetramethyl-imidazolidine-4-thione: Synthesis, structures, luminescence, thermal stability and interaction with DNA.
abstract: Five neutral mononuclear copper(I) halide complexes containing 2,2,5,5-tetramethylimidazolidine-4-thione (tmimdtH) and triphenylphosphane (PPh3) or tri-o-tolylphosphane (totp) have been prepared and structurally characterized by X-ray single-crystal analysis. The complexes containing PPh3 adopt the usual distorted tetrahedral geometry, while the presence of the bulkier totp forces the formation of three-coordinated trigonal planar species. The interaction of the compounds with calf-thymus DNA was monitored directly via UV-vis spectroscopy, DNA-viscosity measurements and indirectly via its competition with ethidium bromide for DNA studied by fluorescence emission spectroscopy. Intercalation was revealed as the most possible mode of binding. Furthermore, luminescent properties and thermal stabilities of the complexes were investigated.
authors: Laboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
authors: D
authors: D
authors: Anastasiadou
authors: Laboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece. Electronic address: gepsomas@chem.auth.gr.
authors: G
authors: G
authors: Psomas
authors: Laboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
authors: M
authors: M
authors: Lalia-Kantouri
authors: Laboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
authors: A G
authors: AG
authors: Hatzidimitriou
authors: Laboratory of Inorganic Chemistry, Department of Chemistry, Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece. Electronic address: aslanidi@chem.auth.gr.
authors: P
authors: P
authors: Aslanidis
mesh_terms: D003300:Copper / Q000737:chemistry*; D004247:DNA / Q000737:chemistry*; D048288:Imidazolines / Q000138:chemical synthesis / Q000737:chemistry; D049408:Luminescent Agents / Q000138:chemical synthesis / Q000737:chemistry; D014320:Triphenylmethyl Compounds / Q000138:chemical synthesis / Q000737:chemistry
chemical_list: D048288:Imidazolines; D049408:Luminescent Agents; D014320:Triphenylmethyl Compounds; D003300:Copper; D004247:DNA
keywords: 2,2,5,5-Tetramethylimidazolidine-4-thione; Copper(I); Crystal structures; Interaction with DNA; TG/DTG-DTA