title: Evaluation of Cardiovascular Risk Factors, Haematological and Biochemical Parameters, and Serum Endocan Levels in Patients with Lichen Planus.
abstract: OBJECTIVE
  The current study aimed to evaluate cardiovascular risk factors, haematological and biochemical parameters, and serum endocan concentrations in lichen planus (LP) patients.
  
  
  METHODS
  This study was conducted with 86 cases, including 43 LP patients and 43 healthy controls. Cardiovascular risk factors, haematological and biochemical parameters, and endocan levels were evaluated.
  
  
  RESULTS
  The serum endocan concentrations of LP patients were not significantly different from those of the healthy controls (p > 0.05). There were no significant differences in the serum endocan levels according to classification by cardiovascular risk factors and smoking history (p > 0.05). In the LP group, white blood cell count, platelet distribution width and monocyte count/high-density lipoprotein cholesterol ratios were significantly higher when compared to the healthy controls (p < 0.05). The LP group had a lower mean platelet volume than the healthy controls (p < 0.05).
  
  
  CONCLUSIONS
  Serum endocan levels did not change significantly in patients with LP, and there were significant differences in haematological and biochemical parameters.
authors: Department of Dermatology, Kayseri Training and Research Hospital, Kayseri, Turkey.
authors: Emin
authors: E
authors: Ozlu
authors: Ayse Serap
authors: AS
authors: Karadag
authors: Aybala E
authors: AE
authors: Toprak
authors: Tugba K
authors: TK
authors: Uzuncakmak
authors: Fethullah
authors: F
authors: Gerin
authors: Feyza
authors: F
authors: Aksu
authors: Ozlem
authors: O
authors: Ozakpınar
authors: Necmettin
authors: N
authors: Akdeniz
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood; D002318:Cardiovascular Diseases / Q000097:blood / Q000453:epidemiology / Q000209:etiology*; D008076:Cholesterol, HDL / Q000097:blood*; D005260:Female; D006801:Humans; D015994:Incidence; D008010:Lichen Planus / Q000097:blood / Q000150:complications*; D008297:Male; D008875:Middle Aged; D009363:Neoplasm Proteins / Q000097:blood*; D010976:Platelet Count; D011509:Proteoglycans / Q000097:blood*; D018570:Risk Assessment / Q000379:methods*; D012307:Risk Factors; D014421:Turkey / Q000453:epidemiology
chemical_list: D015415:Biomarkers; D008076:Cholesterol, HDL; C101134:ESM1 protein, human; D009363:Neoplasm Proteins; D011509:Proteoglycans