title: Preparation, characterization and antimicrobial applications of Zn-Fe LDH against MRSA.
abstract: Facile and simple processes to get Zn-Fe layered double hydroxide (LDH) with nitrate as the interlayer anion are reported. The method of co-precipitation produced high crystallinity LDH that is marked by XRD, SEM, TEM and FT-IR. Results showed that 99.8% of Cd(+2) removals were at pH11 and 4h. To get the adsorption isotherms, the concentration of metal ions extending from 6 to 18mg/L was utilized. Results supported the Langmuir adsorption model. In contrary, the adsorption process followed the pseudo-second-order reaction kinetics. Interestingly, the prepared LDH shows durable antimicrobial activities against Gram-negative (Proteous vulgaris, Klebsiella pneumoniae, Escherichia coli and Pseudomonas aeruginosa) and Gram-positive (Staphylococcus epidermidis, Staphylococcus aureus, Streptococcus pyogenes and MRSA) and fungi (Candida albicans, Aspergillus fumigatus, Geotricumcandidum, and Trichophyton mentagrophytes). The minimum inhibitory concentration (MIC) of Zn-Fe LDH varied from 0.49 to 15.60μg/mL according to the types of microorganisms. The prepared LDH achieved 90% at pH8.50 which is the pH of wastewater and at the same time exhibited durable antimicrobial activities against MRSA, Gram-negative, Gram-positive and fungi. Results have significant implications in the field of bioremediation of water with little cost, simple operation, high productivity and easiness of the equipment.
authors: Materials Science Lab, Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt. Electronic address: samah.mohamed@science.bsu.edu.eg.
authors: S A Abdel
authors: SAA
authors: Moaty
authors: Materials Science and Nanotechnology Department, Faculty of Postgraduate Studies for Advanced Sciences, (PSAS) Beni-Suef University, Egypt.
authors: A A
authors: AA
authors: Farghali
authors: Chemistry Department, Faculty of Science, Beni-Suef University, Beni-Suef, Egypt.
authors: Rehab
authors: R
authors: Khaled
mesh_terms: D000900:Anti-Bacterial Agents / Q000737:chemistry / Q000494:pharmacology; D004305:Dose-Response Relationship, Drug; D005290:Ferric Compounds / Q000737:chemistry / Q000494:pharmacology; D006090:Gram-Negative Bacteria / Q000254:growth & development; D006878:Hydroxides / Q000737:chemistry / Q000494:pharmacology; D007501:Iron; D055624:Methicillin-Resistant Staphylococcus aureus / Q000254:growth & development*; D017967:Zinc Compounds / Q000737:chemistry / Q000494:pharmacology
chemical_list: D000900:Anti-Bacterial Agents; D005290:Ferric Compounds; D006878:Hydroxides; D017967:Zinc Compounds; C021024:ferric hydroxide; D007501:Iron; C052745:zinc hydroxide
keywords: Adsorption; Antimicrobial activity; Cadmium ions; LDH; Zinc- Fe