title: [Not Available].
abstract: BACKGROUND
  Heart failure (HF) patients develop important changes in body composition, but only a small number of studies have evaluated the associations between these changes and functional class deterioration in a prospective manner.
  
  
  OBJECTIVE
  The aim of this study was to evaluate whether changes in bioimpedance parameters were associated with NYHA functional class deterioration over six months.
  
  
  METHODS
  A total of 275 chronic stable HF patients confirmed by echocardiography were recruited. Body composition measurements were obtained by whole body bioelectrical impedance with multiple frequency equipment (BodyStat QuadScan 4000). We evaluated functional class using the New York Heart Association (NYHA) classification at baseline and after six months.
  
  
  RESULTS
  According to our results, 66 (24%) subjects exhibited functional class deterioration, while 209 improved or exhibited no change. A greater proportion of patients exhibited higher extracellular water (> 5%), and these patients developed hypervolemia, according to location on the resistance/reactance graph. A 5% decrease in resistance/height was associated with functional class deterioration with an OR of 1.42 (95% CI 1.01-2.0, p = 0.04).
  
  
  CONCLUSIONS
  Body composition assessment through bioelectrical impedance exhibited a valuable performance as a marker of functional class deterioration in stable HF patients.
authors: Heart Failure Clinic and Clinical Nutrition Department. Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán". Mexico City, Mexico. cam7125@gmail.com.
authors: Lilia
authors: L
authors: Castillo-Martínez
authors: Cira
authors: C
authors: Santillan-Díaz
authors: Arturo
authors: A
authors: Orea-Tejeda
authors: Manuel A
authors: MA
authors: Gómez-Martínez
authors: Fernanda
authors: F
authors: Bernal-Ceballos
authors: Mariel
authors: M
authors: Lozada-Mellado
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001823:Body Composition; D018450:Disease Progression; D017097:Electric Impedance; D015633:Extravascular Lung Water / Q000378:metabolism; D005260:Female; D006333:Heart Failure / Q000145:classification / Q000000981:diagnostic imaging / Q000473:pathology*; D006801:Humans; D008137:Longitudinal Studies; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies
keywords: Bioelectrical impedance analyses. Functional class deterioration. Heart failure.