title: Incidence trends of colorectal cancer in Iran during 2000-2009: A population-based study.
abstract: BACKGROUND
  As the third leading cause of death, cancers have a special place in the Iranian health system. Several studies have been done in some regions of the country with few years of follow-ups, but this was the first standardized study to investigate the incidence trends of colorectal cancer in Iran in a one-decade period.
  
  
  METHODS
  The registered data for colorectal cancer cases in National Cancer Registry System were extracted from the Center for Disease Control & Management of Ministry of Health. The codes from 18 to 21 among cancers were selected for colon and rectum cancers. Incidence rates were directly standardized, using WHO population. The significance of incidence rate trends was tested through Poisson regression.
  
  
  RESULTS
  In this study, 36,650 cases of colorectal cancer were observed for 10 years in Iran, which increased from 813 cases in 2000 to 6,210 cases in 2009. Gender ratio of men to women was 1.39. Significant increasing trends of colorectal cancer were observed during the period of the study. The standardized incidence rate increased from 1.6 per 100,000 persons per year in 2000 to 11.3 in 2009 in males (p<0.001), and it increased from 1.6 per 100,000 persons per year in 2000 to 10.9 in 2009 in females (p<0.001).
  
  
  CONCLUSIONS
  Colorectal cancer has an increasing trend in Iran. The rising trend of colorectal cancer as well as other types of cancers is partially due to improvement in cancer registry systems in the early years of registry. Moreover, westernized lifestyle and an increase in environmental risks could explain this rising trend.
authors: MSc Student of Nursing, Nursing and Midwifery School, Iran University of Medical Sciences, Tehran, Iran, & Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran. e.abdi.fard@gmail.com.
authors: Edris
authors: E
authors: Abdifard
authors: BSc Student of Nursing, Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran. sudabe.amini1991@yahoo.com.
authors: Sudabe
authors: S
authors: Amini
authors: BSc Student of Nursing, Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran. sattarbab85@gmail.com.
authors: Sattar
authors: S
authors: Bab
authors: BSc Student of Midwifery, Students Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran. nasimmasroor@yahoo.com.
authors: Nasim
authors: N
authors: Masroor
authors: Assistant Professor, Department of Medical Surgical Nursing, Nursing and Midwifery School, Iran University of Medical Sciences, Tehran, Iran. alicekhachian@hotmail.com.
authors: Alice
authors: A
authors: Khachian
authors: PhD Student of Epidemiology, Research Center for Modeling in Health, Institute for Futures Studies in Health, Kerman University of Medical Sciences, Kerman, Iran. heidari_m@kmu.ac.ir.
authors: Mohammad
authors: M
authors: Heidari
keywords: Cancer; Colorectal; Incidence Trend; Iran