title: Synthesis of ω9-tetracosynoic and ω9-octacosynoic acids as entries into tritiated metabolic precursors ofcis-9-tricosene andcis-9-heptacosene in the housefly.
abstract: The syntheses of 15-tetracosynoic acid (ω9-tetracosynoic acid) and 19-octacosynoic acid (ω9-octacosynoic acid) are described. These alkynoic acids are to be tritiated to the corresponding alkenoic acids, which will be used as metabolic precursors of housefly pheromone components. The final step in each synthesis involved the coupling of 1-decyne to the lithio-salt of the appropriate ω-bromoacid. Homologation of dibromoalkanes was accomplished with triphasic catalytic displacement of bromide by cyanide ion. Oxidation of a bromo-alcohol to a bromoacid was performed in benzene with KMnO4 and 18-crown-6 ether.
authors: Insect Biochemistry and Physiology, Biosciences Research Laboratory, ARS-USDA, State University Station, P.O. Box 5674, 58105, Fargo, ND.
authors: J
authors: J
authors: George Pomonis
authors: Insect Biochemistry and Physiology, Biosciences Research Laboratory, ARS-USDA, State University Station, P.O. Box 5674, 58105, Fargo, ND.
authors: H
authors: H
authors: Hakk