title: Pituitary Non-Functioning Adenoma Disclosed at 18F-Choline PET/CT to Investigate a Prostate Cancer Relapse.
abstract: We report the incidental finding of a pituitary macroadenoma on an F-choline PET/CT in a patient with recurrent prostate cancer. The pituitary gland was clearly enlarged and intensely FDG avid (SUVmax, 6.6). The diagnosis was confirmed by a subsequent contrast-enhanced MR evaluation, and the macroadenoma was classified as nonfunctioning on the basis of normality of the specific serum hormonal profile. A follow-up F-choline PET/CT scan performed after 6 months revealed stable dimension, and uptake of the pituitary macroadenoma patient deceased 1 month later. At autopsy, intracytoplasmic vesicles containing growth and prolactin hormones were observed at immunohistochemistry.
authors: From the Departments of *Nuclear Medicine, †Radiation Oncology, and ‡Clinical Oncology, Santa Maria della Misericordia Hospital, Rovigo, Italy; and §Department of Radiology, University of Southern California, Los Angeles, CA.
authors: Anna Margherita
authors: AM
authors: Maffione
authors: Giovanni
authors: G
authors: Mandoliti
authors: Felice
authors: F
authors: Pasini
authors: Patrick M
authors: PM
authors: Colletti
authors: Domenico
authors: D
authors: Rubello
mesh_terms: D000236:Adenoma / Q000150:complications* / Q000000981:diagnostic imaging*; D002794:Choline / Q000031:analogs & derivatives*; D006801:Humans; D033162:Incidental Findings; D008297:Male; D008875:Middle Aged; D010911:Pituitary Neoplasms / Q000150:complications* / Q000000981:diagnostic imaging*; D000072078:Positron Emission Tomography Computed Tomography; D011471:Prostatic Neoplasms / Q000150:complications*; D012008:Recurrence
chemical_list: C516370:fluoromethylcholine; D002794:Choline