title: [MODERN PROKINETICS AND THEIR ROLE IN THE TREATMENT OF GASTROENTEROLOGICAL PATHOLOGY].
abstract: The importance of prokinetics (drugs stimulating motor function of the gastrointestinal tract) arises from the high prevalence of gastroenterological pathology associated with primary or secondary disturbances of this function in esophagus, stomach, and intestines. The main groups of prokinetics are beta-blockers of dopamine receptors, inhibitors of acetylcholine esterase (or their combination with dopamine receptor blockers), 5-HT4-receptor agonists. They find wide application for the treatment of gastroesophgeal reflux disease, functional dyspepsia and constipation, obstipational form of irritable bowel syndrome, and other conditions accompanied by motor function disorders of the gastrointestinal tract.
authors: A A
authors: AA
authors: Sheptulin
authors: I B
authors: IB
authors: Belousova
mesh_terms: D002800:Cholinesterase Inhibitors / Q000494:pharmacology*; D018492:Dopamine Antagonists / Q000494:pharmacology*; D005767:Gastrointestinal Diseases / Q000188:drug therapy / Q000503:physiopathology; D005769:Gastrointestinal Motility / Q000187:drug effects*; D041981:Gastrointestinal Tract / Q000503:physiopathology; D006801:Humans; D058828:Serotonin 5-HT4 Receptor Agonists / Q000494:pharmacology*; D016896:Treatment Outcome
chemical_list: D002800:Cholinesterase Inhibitors; D018492:Dopamine Antagonists; D058828:Serotonin 5-HT4 Receptor Agonists