title: Cyclooctyne [60]fullerene hexakis adducts: a globular scaffold for copper-free click chemistry.
abstract: The synthesis of a new highly symmetric hexakis adduct of C60 appended with 12 cyclooctyne moieties has been carried out. This compound has been used for the copper-free strain-promoted cycloaddition reaction to a series of azides with excellent yields. This strategy for the obtention of clicked adducts of [60]fullerene is of special interest for biological applications.
authors: Departamento de Química Orgánica, Fac. CC. Químicas, Universidad Complutense de Madrid, Av. Complutense s/n, 28040 Madrid, Spain. nazmar@ucm.es and Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), CSIC-Universidad de Sevilla, Av. Américo Vespucio 49, 41092 Seville, Spain.
authors: Javier
authors: J
authors: Ramos-Soriano
authors: Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), CSIC-Universidad de Sevilla, Av. Américo Vespucio 49, 41092 Seville, Spain.
authors: José J
authors: JJ
authors: Reina
authors: Departamento de Química Orgánica, Fac. CC. Químicas, Universidad Complutense de Madrid, Av. Complutense s/n, 28040 Madrid, Spain. nazmar@ucm.es.
authors: Alfonso
authors: A
authors: Pérez-Sánchez
authors: Departamento de Química Orgánica, Fac. CC. Químicas, Universidad Complutense de Madrid, Av. Complutense s/n, 28040 Madrid, Spain. nazmar@ucm.es.
authors: Beatriz M
authors: BM
authors: Illescas
authors: Glycosystems Laboratory, Instituto de Investigaciones Químicas (IIQ), CSIC-Universidad de Sevilla, Av. Américo Vespucio 49, 41092 Seville, Spain.
authors: Javier
authors: J
authors: Rojo
authors: Departamento de Química Orgánica, Fac. CC. Químicas, Universidad Complutense de Madrid, Av. Complutense s/n, 28040 Madrid, Spain. nazmar@ucm.es and IMDEA-Nanoscience, Campus Cantoblanco, 28049 Madrid, Spain.
authors: Nazario
authors: N
authors: Martín