title: Simple Preparation of Rhodococcus erythropolis DSM 44534 as Biocatalyst to Oxidize Diols into the Optically Active Lactones.
abstract: In the current study, we present a green toolbox to produce ecological compounds like lactone moiety. Rhodococcus erythropolis DSM 44534 cells have been used to oxidize both decane-1,4-diol () and decane-1,5-diol () into the corresponding γ- () and δ-decalactones () with yield of 80% and enantiomeric excess (ee) = 75% and ee = 90%, respectively. Among oxidation of meso diols, (-)-(1S,5R)-cis-3-oxabicyclo[4.3.0]non-7-en-2-one (5a) with 56% yield and ee = 76% as well as (-)-(2R,3S)-cis-endo-3-oxabicyclo[2.2.1]dec-7-en-2-one (6a) with 100% yield and ee = 90% were formed. It is worth mentioning that R. erythropolis DSM 44534 grew in a mineral medium containing ethanol as the sole source of energy and carbon Chirality 28:623-627, 2016. © 2016 Wiley Periodicals, Inc.
authors: Neubrandenburg University of Applied Sciences, Neubrandenburg, Germany.
authors: Enriqueta
authors: E
authors: Martinez-Rojas
authors: Department of Chemistry, University of Environmental and Life Sciences, Wrocław, Poland.
authors: Teresa
authors: T
authors: Olejniczak
authors: Department of Biotechnology, TU Berlin, Bioanalytics GG6, Berlin, Germany.
authors: Konrad
authors: K
authors: Neumann
authors: Neubrandenburg University of Applied Sciences, Neubrandenburg, Germany.|Department of Biotechnology, TU Berlin, Bioanalytics GG6, Berlin, Germany.
authors: Leif-Alexander
authors: LA
authors: Garbe
authors: Department of Chemistry, University of Environmental and Life Sciences, Wrocław, Poland.
authors: Filip
authors: F
authors: Boratyñski
mesh_terms: D001711:Biotransformation; D002384:Catalysis; D055772:Green Chemistry Technology / Q000379:methods*; D007783:Lactones / Q000737:chemistry*; D012240:Rhodococcus / Q000737:chemistry* / Q000378:metabolism; D013237:Stereoisomerism
chemical_list: D007783:Lactones
keywords: Bacteria; Rhodococcus erythropolis DSM 44534; diols; lactones; oxidation; stereoselectivity