title: Patient-oncologist alliance and psychosocial well-being in Chinese society strongly affect cancer management adherence with cancer of unknown primary.
abstract: Patient-oncologist alliance and psychosocial well-being have strong associations with adherence to cancer management. For patients with cancer of unknown primary (CUP), adherence is crucial to treatment or occult primary screening plans. There has been no study investigating the relationship between alliance, psychosocial factors, and adherence in such patients or in Chinese sociocultural settings.
  
  
  
  The measures of alliance, psychosocial well-being, and adherence willingness were administered to patients with CUP, with a mean age of 58.33 ± 11.24 years. Multiple linear regression models were applied to investigate the independent relationship between alliance and adherence by controlling for socioeconomic and psychosocial confounders.
  
  
  
  Alliance was found to be independently and positively associated with greater adherence willingness and adherence to treatment and follow-up screening after controlling for significant confounders, including medical conditions, psychosocial well-being variables, and socioeconomic factors.
  
  
  
  Stronger patient-oncologist alliance may foster enhanced adherence to treatment and follow-up screening in patients with CUP. Patient-oncologist alliance seems affected by socioeconomic factors and psychosocial well-being in the Chinese sociocultural settings.
authors: Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, China.|Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors: Yifei
authors: Y
authors: Ma
authors: Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors: Wei
authors: W
authors: Xu
authors: Department of Education and Inspiration, Pudong Special Education School, Shanghai, China.
authors: Zhigao
authors: Z
authors: Liang
authors: Department of Neuro-oncology, Neurosurgery Institute, Beijing, China.
authors: Yiming
authors: Y
authors: Li
authors: Department of Pathology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors: Hongyu
authors: H
authors: Yu
authors: Department of PET/CT Radiology, Panorama Medical Imaging Center, Shanghai, China.|Department of PET/CT Radiology Center, Number 85 Hospital of PLA, Shanghai, China.
authors: Chunshan
authors: C
authors: Yang
authors: Department of Stomatology, The First People's Hospital of Shangqiu, Shangqiu, Henan Province, China.
authors: Jidong
authors: J
authors: Li
authors: Department of Education and Inspiration, Pudong Special Education School, Shanghai, China.
authors: Shuang
authors: S
authors: Liang
authors: Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors: Tielong
authors: T
authors: Liu
authors: Department of Orthopedic Oncology, Changzheng Hospital, Second Military Medical University, Shanghai, China.
authors: Jianru
authors: J
authors: Xiao
mesh_terms: D000368:Aged; D002681:China; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009382:Neoplasms, Unknown Primary / Q000523:psychology* / Q000628:therapy*; D010817:Physician-Patient Relations; D000074822:Treatment Adherence and Compliance / Q000523:psychology*
keywords: Chinese cultural settings; adherence; cancer of unknown primary; patient-oncologist alliance; psychosocial well-being