title: Interest of fecal calprotectine dosage in inflammatory bowel diseases, state of the art and perspectives.
abstract: Inflammatory bowel diseases are chronic diseases that result from an inflammation of the intestinal wall. They are suspected in any patient presenting with intestinal symptoms. Until recently, diagnosis was mainly based both on clinical and endoscopic arguments. The use of an easy, fast, reliable, non-invasive and inexpensive test must not only assist in the diagnosis but also contribute to their evolutionary and therapeutic monitoring. To date, fecal calprotectin is the most documented in this perspective. This marker allows to discriminate between functional and organic bowel processes with good sensitivity and good specificity. The determination of the fecal calprotectin level in stools contributes to the evaluation of the degree of disease activity and monitoring of therapeutic response.
authors: Service de biochimie clinique, Hôpital Beaujon, APHP, Clichy, France.
authors: Tarek
authors: T
authors: Chaabouni
authors: Service de biochimie clinique, Hôpital Beaujon, APHP, Clichy, France, Centre de recherche sur l'inflammation, UMRs-1149, Université Paris Diderot, UFR de Médecine, Paris, France.
authors: Hana
authors: H
authors: Manceau
authors: Service de biochimie clinique, Hôpital Beaujon, APHP, Clichy, France, Centre de recherche sur l'inflammation, UMRs-1149, Université Paris Diderot, UFR de Médecine, Paris, France.
authors: Katell
authors: K
authors: Peoc'h
mesh_terms: D015415:Biomarkers / Q000032:analysis; D003937:Diagnosis, Differential; D003955:Diagnostic Tests, Routine / Q000379:methods* / Q000592:standards / Q000639:trends; D005243:Feces / Q000737:chemistry*; D006801:Humans; D015212:Inflammatory Bowel Diseases / Q000175:diagnosis* / Q000378:metabolism; D039841:Leukocyte L1 Antigen Complex / Q000032:analysis* / Q000378:metabolism; D008991:Monitoring, Physiologic; D011237:Predictive Value of Tests; D012680:Sensitivity and Specificity
chemical_list: D015415:Biomarkers; D039841:Leukocyte L1 Antigen Complex
keywords: diagnosis; inflammation; inflammatory bowel diseases; intestines; stools; therapeutic follow-up