title: Quantitative assessment of the entire right ventricle from one acoustic window: an attractive approach.
abstract: OBJECTIVE
  The aim of this prospective study was to evaluate the feasibility and establish normal values of functional right ventricle (RV) parameters as assessed in our four, long-axis view RV model using iRotate echocardiography. Furthermore, we evaluated the potential use of this model in patients with abnormally loaded RVs.
  
  
  RESULTS
  One hundred and fifty-five healthy subjects aged 20-72 years (≥28 subjects per decile) were prospectively recruited. We used non-dedicated RV speckle-tracking software to test the feasibility and to establish normal range values of peak systolic global longitudinal RV strain (RV-GLS) from the RV free-walls (septum was excluded). Also normal range values for: dimensions, tricuspid annular plane systolic excursion (TAPSE) and tricuspid annular peak systolic velocity (TDI-S') were established. The feasibility of RV-GLS was 88, 84, and 62%, respectively, in the lateral, inferior, and anterior free wall. Mean RV-GLS normal values were -24.5 ± 4.9% for lateral wall and -25.4 ± 5.0% for anterior wall. Mean RV-GLS in the inferior wall was -23.2 ± 4.4% in the aortic (Ao) view and -20.7 ± 5.0% in the coronal (CV) view. The feasibility of mean RV-GLS was 100% in the anterior, lateral, and inferior walls in abnormally dilated RVs.
  
  
  CONCLUSIONS
  The feasibility of all RV parameters assessed in the four-view iRotate model is good to excellent. Normal values for RV dimension and function of the anterior, inferior, and lateral RV walls have been established. Further studies and dedicated RV speckle-tracking software are warranted to discover the full potential of this new technique.
authors: Jackie S
authors: JS
authors: McGhie
authors: Myrthe E
authors: ME
authors: Menting
authors: Wim B
authors: WB
authors: Vletter
authors: René
authors: R
authors: Frowijn
authors: Jolien W
authors: JW
authors: Roos-Hesselink
authors: Heleen B
authors: HB
authors: van der Zwaan
authors: Osama I I
authors: OII
authors: Soliman
authors: Marcel L
authors: ML
authors: Geleijnse
authors: Annemien E
authors: AE
authors: van den Bosch
mesh_terms: D000328:Adult; D000368:Aged; D004452:Echocardiography / Q000379:methods*; D019560:Echocardiography, Three-Dimensional / Q000379:methods; D005069:Evaluation Studies as Topic; D005260:Female; D006352:Heart Ventricles / Q000000981:diagnostic imaging*; D006801:Humans; D007090:Image Interpretation, Computer-Assisted; D008297:Male; D008875:Middle Aged; D015588:Observer Variation; D010865:Pilot Projects; D011446:Prospective Studies; D012016:Reference Values; D012680:Sensitivity and Specificity; D018709:Statistics, Nonparametric; D013318:Stroke Volume / Q000502:physiology*; D016278:Ventricular Function, Right / Q000502:physiology*
keywords: echocardiography; multi-view strain; right ventricle