title: [Recent therapeutic options of (severe) gastrointestinal bleedings].
abstract: With Idarucizumab, a specific antidote to antagonize the effect of dabigatran, is now available in severe bleeding complications under directly oral anticoagulants (DOAC). In endoscopic treatment of severe gastrointestinal bleeding are alternative treatment options also available with hemostasis sprays and new hemostasis clips. Especially in recurrent ulcer bleedings, the newly developed clips can achieve hemostasis and prevent an operational procedure. In patients with coronary heart disease, a liberal transfusion regimen should be considered.
authors: Georg
authors: G
authors: Braun
authors: Andreas
authors: A
authors: Probst
authors: Helmut
authors: H
authors: Messmann
mesh_terms: D000284:Administration, Oral; D061067:Antibodies, Monoclonal, Humanized / Q000627:therapeutic use; D000925:Anticoagulants / Q000627:therapeutic use*; D016099:Endoscopy, Gastrointestinal; D006471:Gastrointestinal Hemorrhage / Q000188:drug therapy* / Q000601:surgery*; D006487:Hemostasis; D006801:Humans
chemical_list: D061067:Antibodies, Monoclonal, Humanized; D000925:Anticoagulants; C000594745:idarucizumab