title: Clinical significance of nutritional status in patients with atrial fibrillation: An overview of current evidence.
abstract: Obesity is a well-known atherosclerosis risk factor; however, its role and the importance of undernutrition in atrial fibrillation (AF) pathogenesis are still not well understood. The aim of this study was to present the current state of knowledge on this issue in different groups of patients.
  
  
  
  Systematic review of papers published between 1980 and 2016.
  
  
  
  The literature shows contradicting views regarding the impact of nutritional status on the risk, course, and complications of AF. On the one hand, it has been revealed that overweight, obesity, and high birth mass increase the risk of AF, and that their reduction is linked to an improved course of AF and reduced all-cause and cardiovascular mortality. On the other hand, a so-called obesity paradox has been found, which shows lower all-cause mortality in overweight patients with AF compared to those of normal weight or who are underweight. It has also been shown, although based on a small number of studies, that the relationship between nutritional status and risk of AF and its complication may be U-shaped, which means that not only patients with obesity, but also individuals with underweight, cachexia, and low birth weight may have an increased risk and poor outcome of AF.
  
  
  
  The relationship between patients' nutritional status and the course of AF has become clearer but it requires further studies examining the importance of weight reduction on AF course.
authors: Clinic of Vascular and Internal Diseases, Jan Biziel University Hospital No. 2 in Bydgoszcz, Bydgoszcz, Poland.
authors: Marzena
authors: M
authors: Anaszewicz
authors: Clinic of Vascular and Internal Diseases, Jan Biziel University Hospital No. 2 in Bydgoszcz, Bydgoszcz, Poland; Department of Vascular and Internal Diseases; Faculty of Health Sciences, Ludwik Rydygier Collegium Medicum in Bydgoszcz, Nicolaus Copernicus University in Toruń, Toruń, Poland. Electronic address: budz@cps.pl.
authors: Jacek
authors: J
authors: Budzyński
mesh_terms: D001281:Atrial Fibrillation / Q000401:mortality / Q000503:physiopathology*; D001835:Body Weight / Q000502:physiology*; D018450:Disease Progression; D006801:Humans; D009752:Nutritional Status / Q000502:physiology*; D011379:Prognosis; D012307:Risk Factors
keywords: Atrial fibrillation; Malnutrition; Nutritional status; Obesity; Prognosis