title: Isotopic labeling of phosphatidylcholine in the choline moiety.
abstract: Two simple methods for the synthesis of phosphatidylcholine (lecithin) isotopically labeled in the methyl group of the choline moiety are described. Phosphatidylcholine is converted to phosphatidyl-ethanolamine by enzymic transphosphatidylation, and this is methylated using either methyl iodide or diazomethane to give a product isotopically enriched in all three choline methyl groups.
authors: Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QW, Cambridge, UK.
authors: G A
authors: GA
authors: Smith
authors: Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QW, Cambridge, UK.
authors: C
authors: C
authors: Montecucco
authors: Department of Biochemistry, University of Cambridge, Tennis Court Road, CB2 1QW, Cambridge, UK.
authors: J P
authors: JP
authors: Bennett