title: Spiny hyperkeratosis (trichodysplasia spinulosa-like eruption): a cutaneous adverse effect of Hedgehog pathway inhibitors involving expression of p16.
authors: Department of Dermatology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.|Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: I
authors: I
authors: López-Lerma
authors: Department of Pathology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
authors: B
authors: B
authors: Ferrer
authors: Department of Dermatology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
authors: I
authors: I
authors: Zarzoso
authors: Department of Pathology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.
authors: J
authors: J
authors: Hernández-Losa
authors: Department of Dermatology, Hospital Universitari Vall d'Hebron, Barcelona, Spain.|Universitat Autònoma de Barcelona, Barcelona, Spain.
authors: V
authors: V
authors: García-Patos
mesh_terms: D000368:Aged; D001706:Biopsy; D019941:Cyclin-Dependent Kinase Inhibitor p16 / Q000096:biosynthesis / Q000235:genetics*; D003561:Cytarabine / Q000009:adverse effects*; D006201:Hair Diseases / Q000139:chemically induced* / Q000175:diagnosis / Q000378:metabolism; D018859:Hair Follicle / Q000473:pathology; D053823:Hedgehog Proteins / Q000187:drug effects / Q000378:metabolism*; D006801:Humans; D007166:Immunosuppressive Agents / Q000009:adverse effects; D007642:Keratosis / Q000139:chemically induced* / Q000175:diagnosis / Q000378:metabolism; D008297:Male; D012867:Skin / Q000473:pathology
chemical_list: C000614131:CDKN2A protein, human; D019941:Cyclin-Dependent Kinase Inhibitor p16; D053823:Hedgehog Proteins; D007166:Immunosuppressive Agents; D003561:Cytarabine