title: Influence of the Dermis Thickness on the Results of the Skin Treatment with Monopolar and Bipolar Radiofrequency Currents.
abstract: Electrically layered tissue structure significantly modifies distribution of radiofrequency (RF) current in the dermis and in the subcutaneous adipose tissue comparing to that in a homogeneous medium. On the basis of the simple model of RF current distribution in a two-layer skin containing dermis and subcutis, we assess the influence of the dermal thickness on the current density in different skin layers. Under other equal conditions, current density in the dermis is higher for the skin having thinner dermis. This contradicts the main paradigm of the RF theory stating that treatment results are mainly dependent on the maximal temperature reached in a target tissue, since the best short- and long-term clinical results of RF application to the skin were reported in the areas having thicker dermis. To resolve this contradiction, it is proposed that the long-term effect of RF can be realized through a structural modification of the subcutaneous fat depot adjacent to the treated skin area. Stimulation of these cells located near the interface dermis/subcutis will demand the concentration of applied RF energy in this area and will require the optimal arrangement of RF electrodes on the skin surface.
authors: Scientific Department, Wellcomet GmbH, 76229 Karlsruhe, Germany.
authors: Ilja L
authors: 0000-0002-4031-8203
authors: IL
authors: Kruglikov
mesh_terms: D000273:Adipose Tissue / Q000033:anatomy & histology / Q000528:radiation effects*; D020405:Dermis / Q000033:anatomy & histology / Q000528:radiation effects*; D004566:Electrodes; D006801:Humans; D008962:Models, Theoretical; D061208:Pulsed Radiofrequency Treatment; D012867:Skin / Q000033:anatomy & histology / Q000528:radiation effects*; D013696:Temperature