title: Recovery with a regular dose of antibiotics from bacillary hemoglobinuria in a Holstein cow.
abstract: One Holstein cow housed with 21 other cows exhibited clinical signs of pyrexia, anorexia and diarrhea along with severe hemoglobinuria. Hematological and biochemical analyses conducted before and after antibiotic therapy indicated severe hemolytic anemia and disruption of hepatic function. A general improvement in conditions was observed after an 11-day program of treatment comprising a regular dose of antibiotics and prescribed supportive therapies. A tentative diagnosis of bacillary hemoglobinuria was made based on the clinical and clinico-pathologic features on day 7. A molecular diagnosis was made by a PCR amplification of the flagellin gene of Clostridium haemolyticum using DNA extracted from the whole blood. The cow was diagnosed with the first recorded occurrence of bacillary hemoglobinuria of Holstein cattle in Japan.
authors: Laboratory of Theriogenology, Joint Faculty of Veterinary Medicine, Yamaguchi University, 1677-1 Yoshida, Yamaguchi-shi, Yamaguchi 753-8511, Japan.
authors: Mitsuhiro
authors: M
authors: Takagi
authors: Moeko
authors: M
authors: Kohyama
authors: Tetsushi
authors: T
authors: Ono
authors: Satoshi
authors: S
authors: Adachi
authors: Daiji
authors: D
authors: Shirao
authors: Hidenori
authors: H
authors: Tamura
authors: Masayasu
authors: M
authors: Taniguchi
authors: Akira
authors: A
authors: Yabuki
authors: Osamu
authors: O
authors: Yamato
mesh_terms: D000743:Anemia, Hemolytic / Q000382:microbiology / Q000662:veterinary; D000818:Animals; D000900:Anti-Bacterial Agents / Q000627:therapeutic use*; D002417:Cattle; D002418:Cattle Diseases / Q000188:drug therapy / Q000382:microbiology* / Q000652:urine; D003013:Clostridium / Q000302:isolation & purification*; D003015:Clostridium Infections / Q000188:drug therapy / Q000382:microbiology / Q000652:urine / Q000662:veterinary*; D005260:Female; D006456:Hemoglobinuria / Q000188:drug therapy / Q000382:microbiology / Q000662:veterinary*; D007564:Japan
chemical_list: D000900:Anti-Bacterial Agents