title: Data on cell growth inhibition induced by anti-VEGF siRNA delivered by Stealth liposomes incorporating G2 PAMAM-cholesterol versus Metafectene® as a function of exposure time and siRNA concentration.
abstract: In this data article, carboxyfluorescein-loaded liposomes were prepared and purified from free carboxyfluorescein using gel filtration chromatography in the first part. In the next part, following preparation of anti-VEGF siRNA loaded liposomes incorporating hydrophobically modified G2 PAMAM dendrimer (G2-Chol40%) (Golkar et al., 2016) [1], the cell growth inhibition induced by the formulations (siRNA/Metafectene complexes and siRNA loaded liposomes incorporating hydrophobic G2) was evaluated at two exposure times through MTT assay in a breast cancer cell (SKBR-3) and compared by two-way ANOVA.
authors: Pharmaceutics Department, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71345, Iran.
authors: Nasim
authors: N
authors: Golkar
authors: Pharmaceutics Department, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71345, Iran; Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz 71345, Iran.
authors: Soliman Mohammadi
authors: SM
authors: Samani
authors: Center for Nanotechnology in Drug Delivery, Shiraz University of Medical Sciences, Shiraz 71345, Iran; Pharmaceutical Nanotechnology Department, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz 71345, Iran.
authors: Ali Mohammad
authors: AM
authors: Tamaddon
keywords: Anti-VEGF siRNA; Cell growth inhibition; Liposome; Polyamidoaminedendrimer