title: Restoration of fertility in prolactin induced premature menopause : A report of an eight year case study.
abstract: A case of infertility associated initially with amenorrhoea only and then with amenorrhoea and galactorrhoea following a successfully induced pregnancy is reported. In a period of eight years of continuous investigation and treatment this subject's infertility first responded to sequential clomiphene and human chorionic gonadotrophin (HCG) therapy resulting in a normal pregnancy. Subsequently she became refractory to this therapy. The availability of specific prolactin assays and a prolactin inhibitor (2-Br-α-ergocryptine, bromocriptine Sandoz) identified the aetiology of her amenorrhoea/galactorrhoea/infertility and provided a new mode of therapy. Planned conception has been achieved on three occasions, producing two normal males and a normal female child.
authors: Endocrine Investigation Centre, Department of Psychiatry, U.C.D., St. James Hospital, Dublin 8.
authors: A
authors: A
authors: Darragh
authors: Endocrine Investigation Centre, Department of Psychiatry, U.C.D., St. James Hospital, Dublin 8.
authors: D A
authors: DA
authors: O'Kelly
authors: Professorial Unit, Royal College of Surgeons, Rotunda Hospital, Dublin 1.
authors: A D
authors: AD
authors: Browne
authors: Sandoz Limited, Basel, Switzerland.
authors: E
authors: E
authors: Del Pozo