title: Manganese-Catalyzed Carboacylations of Alkenes with Alkyl Iodides.
abstract: A manganese-catalyzed carboacylation of alkenes with alkyl iodides and carbon monoxide is described. This carbonylative difunctionalization uses both primary and secondary alkyl iodides in reactions with a diverse array of cyclic and acyclic substrates. Examples of successful applications to the synthesis of five-, six-, and seven-membered rings are provided. The inexpensive, first-row catalytic system and mild reaction conditions are expected to facilitate applications in complex synthesis.
authors: Department of Chemistry, The University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
authors: Caitlin M
authors: CM
authors: McMahon
authors: Department of Chemistry, The University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
authors: Matthew S
authors: MS
authors: Renn
authors: Department of Chemistry, The University of North Carolina at Chapel Hill , Chapel Hill, North Carolina 27599, United States.
authors: Erik J
authors: EJ
authors: Alexanian
mesh_terms: D000475:Alkenes / Q000737:chemistry*; D002248:Carbon Monoxide / Q000737:chemistry; D002384:Catalysis; D006571:Heterocyclic Compounds / Q000138:chemical synthesis* / Q000737:chemistry; D006847:Hydrocarbons, Iodinated / Q000737:chemistry*; D008345:Manganese / Q000737:chemistry*; D015394:Molecular Structure
chemical_list: D000475:Alkenes; D006571:Heterocyclic Compounds; D006847:Hydrocarbons, Iodinated; D008345:Manganese; D002248:Carbon Monoxide