title: CAPing inflammation and acute kidney injury.
abstract: The cholinergic anti-inflammatory pathway has been shown to modulate inflammation in disease models such as rheumatoid arthritis and inflammatory bowel disease. A recent study demonstrated a protective effect of vagus nerve stimulation with activation of the cholinergic anti-inflammatory pathway in the ischemia reperfusion model of acute kidney injury.
authors: Division of Nephrology, University of Virginia, Charlottesville, Virginia, USA; Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia, Charlottesville, Virginia, USA.
authors: Tsuyoshi
authors: T
authors: Inoue
authors: Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia, Charlottesville, Virginia, USA; Department of Pharmacology, University of Virginia, Charlottesville, Virginia, USA.
authors: Diane L
authors: DL
authors: Rosin
authors: Division of Nephrology, University of Virginia, Charlottesville, Virginia, USA; Center for Immunity, Inflammation, and Regenerative Medicine, University of Virginia, Charlottesville, Virginia, USA. Electronic address: mdo7y@virginia.edu.
authors: Mark D
authors: MD
authors: Okusa
mesh_terms: D000109:Acetylcholine; D058186:Acute Kidney Injury; D003317:Corneal Dystrophies, Hereditary; D006801:Humans; D007249:Inflammation; D015427:Reperfusion Injury; D055536:Vagus Nerve Stimulation
chemical_list: D000109:Acetylcholine