title: Newly diagnosed panic disorder and the risk of erectile dysfunction: A population-based cohort study in Taiwan.
abstract: Previous studies indicated that panic disorder is correlated with erectile dysfunction (ED). The primary aim of this study was to explore the incidence rate of ED among panic disorder patients in an Asian country. The secondary aim was to compare the risk of ED in panic disorder patients that were treated with different kinds of antidepressants, and to explore the possible mechanism between these two disorders. We identified 1393 male patients with newly diagnosed panic disorder from the Taiwan's National Health Insurance Database. Four matched controls per case were selected for the study group by propensity score. After adjusting for age, obesity and comorbidities, the panic disorder patients had a higher hazard ratio of ED diagnosis than the controls, especially among the untreated panic disorder patients. This retrospective dynamic cohort study supports the link between ED and prior panic disorder in a large sample of panic disorder patients. This study points out the need of early antidepressant treatment for panic disorder to prevent further ED.
authors: Department of Psychiatry, Taichung Veterans General Hospital, Puli Branch, Taiwan.
authors: Yao-Ting
authors: YT
authors: Wang
authors: Yang Ji Mental Hospital, Taiwan.
authors: Hsi-Han
authors: HH
authors: Chen
authors: Department of Psychiatry, Taichung Veterans General Hospital, Taiwan.
authors: Ching-Heng
authors: CH
authors: Lin
authors: Department of Psychiatry, Taichung Veterans General Hospital, Chiayi Branch, Taiwan.
authors: Shih-Hsiung
authors: SH
authors: Lee
authors: Department of Psychiatry, Taichung Veterans General Hospital, Taiwan.
authors: Chin-Hong
authors: CH
authors: Chan
authors: Bali Psychiatric Center, Ministry of Health and Welfare, Taiwan; Institute of Epidemiology and Preventive Medicine, National Taiwan University, Taiwan; Faculty of Medicine, National Yang-Ming University, Taiwan. Electronic address: s001007@hotmail.com.
authors: Shiau-Shian
authors: SS
authors: Huang
mesh_terms: D000293:Adolescent; D000328:Adult; D000437:Alcoholism / Q000453:epidemiology; D000928:Antidepressive Agents / Q000627:therapeutic use; D002318:Cardiovascular Diseases / Q000453:epidemiology; D015897:Comorbidity; D016208:Databases, Factual; D003920:Diabetes Mellitus / Q000453:epidemiology; D007172:Erectile Dysfunction / Q000453:epidemiology*; D006801:Humans; D006949:Hyperlipidemias / Q000453:epidemiology; D015994:Incidence; D008297:Male; D008875:Middle Aged; D015999:Multivariate Analysis; D016584:Panic Disorder / Q000188:drug therapy / Q000453:epidemiology*; D016016:Proportional Hazards Models; D051436:Renal Insufficiency, Chronic / Q000453:epidemiology; D012107:Research Design; D012189:Retrospective Studies; D012307:Risk Factors; D013624:Taiwan / Q000453:epidemiology; D055815:Young Adult
chemical_list: D000928:Antidepressive Agents
keywords: Antidepressants; Erectile dysfunction; Panic disorder; Taiwan