title: Epidemiology of hepatitis B virus in the cities of the northern region of Espírito Santo, Brazil.
abstract: The World Health Organization (WHO) estimates that approximately 2 billion people worldwide have already had contact with hepatitis B virus (HBV) and 373 million have become chronic carriers. Hepatitis B is a major cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma, leading to a large number of deaths annually. Both viral factors and the host immune response have been implicated in the pathogenesis and clinical result of HBV infection. Many Brazilian cities, including the cities of the northern region of the state of Espírito Santo are located in regions with little health infrastructure. Our study performed an epidemiological analysis of cases of Hepatitis B in São Mateus, using methodology of Geographic Information System (GIS), aiming to raise the number of disease cases, establishing preventive measures to control the disease, improving the quality of life of people affected by this pathology. The city of São Mateus had the largest number of reported cases of hepatitis B northern region of Espírito Santo. The age group with the highest number of hepatitis B notifications was 20-49 years, mostly females. The major forms of contact with HBV in these cities were dental treatment, use of injectable medications, surgical procedures and multiple sexual partners.
authors: Universidade Federal do Espírito Santo, Departamento de Ciências Farmacêuticas, Avenida Marechal Campos, 1468, Bairro Maruípe, 29043-900 Vitória, ES, Brasil.
authors: André M
authors: AM
authors: Fontes
authors: Universidade Federal do Espírito Santo, Departamento de Ciências Farmacêuticas, Avenida Marechal Campos, 1468, Bairro Maruípe, 29043-900 Vitória, ES, Brasil.
authors: Juliana S
authors: JS
authors: Ardisson
authors: Universidade Federal do Espírito Santo, Departamento de Ciências da Saúde, Rodovia BR 101 Norte, Km 60, Bairro Litoranêo, 29932-540 São Mateus, ES, Brasil.
authors: Marco A A
authors: MA
authors: Souza
authors: Universidade Federal do Espírito Santo, Departamento de Engenharia e Tecnologia, Rodovia BR 101 Norte, Km 60, Bairro Litoranêo, 29932-540 São Mateus, ES, Brasil.
authors: Rodrigo R
authors: RR
authors: Freitas
authors: Universidade Federal do Espírito Santo, Departamento de Ciências Farmacêuticas, Avenida Marechal Campos, 1468, Bairro Maruípe, 29043-900 Vitória, ES, Brasil.
authors: João A T
authors: JA
authors: Pancoto
mesh_terms: D000328:Adult; D017677:Age Distribution; D001938:Brazil / Q000453:epidemiology; D006528:Carcinoma, Hepatocellular / Q000821:virology; D002947:Cities / Q000453:epidemiology; D005260:Female; D006509:Hepatitis B / Q000453:epidemiology* / Q000821:virology; D006515:Hepatitis B virus / Q000302:isolation & purification*; D006801:Humans; D008113:Liver Neoplasms / Q000821:virology; D008297:Male; D011788:Quality of Life; D017678:Sex Distribution