title: Comparative analysis of brilliant blue G and an intracameral illuminator in assisting visualization of the anterior capsule in eyes with vitreous hemorrhage.
abstract: To compare the safety and efficacy of 0.025 mg/mL brilliant blue G (BBG) and an intracameral illuminator for visualizing the anterior capsule.
  
  
  
  University-based tertiary referral center, South Korea.
  
  
  
  Retrospective cases series.
  
  
  
  The medical records of patients with vitreous hemorrhage for which they had pars plana vitrectomy and cataract surgery were retrospectively reviewed. The patients were classified into 2 groups. The BBG group comprised patients having capsule staining with BBG. The illuminator group comprised patients who had capsulorhexis assisted with an intracameral illuminator. The status of the endothelial cells was analyzed.
  
  
  
  There were 27 eyes in the BBG group and 35 eyes in the illuminator group. In the BBG group, endothelial cell density (ECD) was reduced 3 months after surgery (10.6% loss) (P = .003). The illuminator group had no significant loss (1.5% loss) (P = .264). The ECD loss was greater in the BBG group than the illuminator group 3 months after surgery (P = .01). There was no statistically significant difference in the coefficient of variation of cell area or percentage of hexagonal cells between the 2 groups.
  
  
  
  The ECD loss was higher in eyes with 0.025 mg/mL BBG staining than in eyes using an intracameral illuminator. Further studies are necessary to establish the safety profile of BBG on the endothelium.
  
  
  
  None of the authors has a financial or proprietary interest in any material or method mentioned.
authors: From the Departments of Ophthalmology, Gyeongsang National University School of Medicine (Y.M. Park), Gyeongsang National University Changwon Hospital, Changwon-si, Gyeongsangnam-do, School of Medicine (J.Y. Park, J.S. Lee, J.E. Lee, S.W. Park), Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, and Pusan National University Yangsan Hospital (Byon), Yangsan, South Korea.
authors: Young Min
authors: YM
authors: Park
authors: From the Departments of Ophthalmology, Gyeongsang National University School of Medicine (Y.M. Park), Gyeongsang National University Changwon Hospital, Changwon-si, Gyeongsangnam-do, School of Medicine (J.Y. Park, J.S. Lee, J.E. Lee, S.W. Park), Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, and Pusan National University Yangsan Hospital (Byon), Yangsan, South Korea.
authors: Jung Y
authors: JY
authors: Park
authors: From the Departments of Ophthalmology, Gyeongsang National University School of Medicine (Y.M. Park), Gyeongsang National University Changwon Hospital, Changwon-si, Gyeongsangnam-do, School of Medicine (J.Y. Park, J.S. Lee, J.E. Lee, S.W. Park), Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, and Pusan National University Yangsan Hospital (Byon), Yangsan, South Korea.
authors: Jong Soo
authors: JS
authors: Lee
authors: From the Departments of Ophthalmology, Gyeongsang National University School of Medicine (Y.M. Park), Gyeongsang National University Changwon Hospital, Changwon-si, Gyeongsangnam-do, School of Medicine (J.Y. Park, J.S. Lee, J.E. Lee, S.W. Park), Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, and Pusan National University Yangsan Hospital (Byon), Yangsan, South Korea.
authors: Ji Eun
authors: JE
authors: Lee
authors: From the Departments of Ophthalmology, Gyeongsang National University School of Medicine (Y.M. Park), Gyeongsang National University Changwon Hospital, Changwon-si, Gyeongsangnam-do, School of Medicine (J.Y. Park, J.S. Lee, J.E. Lee, S.W. Park), Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, and Pusan National University Yangsan Hospital (Byon), Yangsan, South Korea.
authors: Ik Soo
authors: IS
authors: Byon
authors: From the Departments of Ophthalmology, Gyeongsang National University School of Medicine (Y.M. Park), Gyeongsang National University Changwon Hospital, Changwon-si, Gyeongsangnam-do, School of Medicine (J.Y. Park, J.S. Lee, J.E. Lee, S.W. Park), Pusan National University and Medical Research Institute, Pusan National University Hospital, Pusan, and Pusan National University Yangsan Hospital (Byon), Yangsan, South Korea. Electronic address: oph97@naver.com.
authors: Sung Who
authors: SW
authors: Park
mesh_terms: D002387:Cataract Extraction; D006801:Humans; D056910:Republic of Korea; D012189:Retrospective Studies; D012394:Rosaniline Dyes; D014792:Visual Acuity; D014821:Vitrectomy; D014823:Vitreous Hemorrhage / Q000000981:diagnostic imaging* / Q000601:surgery
chemical_list: D012394:Rosaniline Dyes; C004692:coomassie Brilliant Blue