title: Sultiame revisited: treatment of refractory absence seizures.
abstract: Sultiame is recommended for the treatment of benign epilepsy of childhood with centrotemporal spikes, electrical status epilepticus during slow-wave sleep, as well as other genetic (idiopathic) focal epilepsies. Sultiame is not traditionally considered a treatment choice for idiopathic generalised epilepsy, and it does not appear on the list of drugs recommended for treatment of absence seizures. We report the efficacy of sultiame in treating three children with drug-resistant absence seizures and discuss the potential use of sultiame beyond the idiopathic focal epilepsies.
authors: Department of Neurology and Clinical Neurophysiology, Temple Street Children's University Hospital, Dublin 1, Ireland.
authors: Kathleen M
authors: KM
authors: Gorman
authors: Department of Neurology and Clinical Neurophysiology, Temple Street Children's University Hospital, Dublin 1, Ireland.
authors: Amre
authors: A
authors: Shahwan
mesh_terms: D000293:Adolescent; D000927:Anticonvulsants / Q000008:administration & dosage / Q000494:pharmacology*; D002648:Child; D000069279:Drug Resistant Epilepsy / Q000188:drug therapy*; D004832:Epilepsy, Absence / Q000188:drug therapy*; D005260:Female; D006801:Humans; D008297:Male; D013843:Thiazines / Q000008:administration & dosage / Q000494:pharmacology*; D000096926:Benzenesulfonamides
chemical_list: D000927:Anticonvulsants; D013843:Thiazines; C084593:sulthiame; D000096926:Benzenesulfonamides
keywords: absence seizure; childhood absence epilepsy; idiopathic focal epilepsy; refractory; sulthiame