title: Surgical Complications Not Related to the Renal and Pancreatic Grafts After Simultaneous Kidney and Pancreas Transplantation.
abstract: BACKGROUND
  Simultaneous pancreas and kidney transplantation (SPKTx) is the most commonly performed multiorgan transplantation procedure worldwide. Transplanted organs are the main source of complication; however, some postoperative complications are not directly related to the pancreatic or renal grafts. The goal of this study was to evaluate the prevalence, type, and severity of postoperative complications not related to transplanted kidney or pancreas among SPKTx recipients.
  
  
  METHODS
  Complications unrelated to transplanted pancreas and kidneys among 112 SPKTx recipients were analyzed. The cumulative freedom from general surgical complications was assessed, and it was compared with cumulative freedom from complications related to kidney and pancreatic grafts. Severity of complications was classified according to a modified Clavien-Dindo scale.
  
  
  RESULTS
  The general surgery complication rate was 22.2%. Cumulative freedom from general surgical complications at days 60 and 90 after transplantation was 0.89 and 0.87, respectively. Cumulative freedom from general surgical complications was comparable with cumulative freedom from complications related to kidney grafts but significantly higher than cumulative freedom from complications related to pancreatic grafts (log-rank test, P < .001). The rates for grades of severity II, IIIa, IIIb, and IVb were 19.4%, 9.7%, 64.5%, and 6.4%, respectively. The most frequent cause of complications was intra-abdominal hematoma or abscess (25.8%).
  
  
  CONCLUSIONS
  The general surgical complication rate was comparable to the rate of complications originating from the renal grafts but significantly lower than the complication rate related to the transplanted pancreas. The incidence of general surgical complications could be defined as moderate, and the severity of this type of complication was low.
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland. Electronic address: tadeusz.grochowiecki@wum.edu.pl.
authors: T
authors: T
authors: Grochowiecki
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland.
authors: K
authors: K
authors: Madej
authors: Department of General and Endocrine Surgery, Warsaw Medical University, Warsaw, Poland.
authors: Z
authors: Z
authors: Gałązka
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland.
authors: T
authors: T
authors: Jakimowicz
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland.
authors: M
authors: M
authors: Jędrasik
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland.
authors: K
authors: K
authors: Grygiel
authors: Department of Immunology, Transplantology and Internal Diseases, Warsaw Medical University, Warsaw, Poland.
authors: L
authors: L
authors: Pączek
authors: Department of Transplantation Medicine and Nephrology, Warsaw Medical University, Warsaw, Poland.
authors: M
authors: M
authors: Durlik
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland.
authors: S
authors: S
authors: Nazarewski
authors: Department of General, Vascular and Transplant Surgery, Warsaw Medical University, Warsaw, Poland.
authors: J
authors: J
authors: Szmidt
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D015994:Incidence; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D016035:Pancreas Transplantation / Q000009:adverse effects*; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology