title: Clinical features of 10 cases of eyelid sporotrichosis in Jilin Province (Northeast China).
abstract: OBJECTIVE
  Sporotrichosis is a common subcutaneous mycosis caused by an infection with dimorphic fungus Sporothrix schenckii. We present a series of patients with eyelid sporotrichosis and study the clinical and histopathological presentation, microbiology, treatment options, and outcome.
  
  
  METHODS
  A retrospective case-series study of patients with a clinical diagnosis of eyelid sporotrichosis. Records were examined to obtain information regarding patient demographics, presenting symptoms and signs, histopathological examination, microbiology, management, and outcomes.
  
  
  RESULTS
  Ten patients (4 men, 6 women; mean age 46.5 years, range 3-81 years) were included. Based on their clinical manifestations, eyelid sporotrichosis was classified into 3 major forms: (i) fixed cutaneous (6/10 cases), (ii) lymphocutaneous (3/10 cases), and (iii) eyelid abscess (1/10 cases). All the cases were treated with a terbinafine 12-week regimen. Nodules, papules, and abscesses regressed after treatment. No recurrence was discovered after a 12-week follow-up.
  
  
  CONCLUSIONS
  Eyelid sporotrichosis has typical features of clinical manifestations. Histopathological examination and tissue culture are helpful for diagnosis. Confirmed cases normally require long-term systematic treatment with antifungal agents, but surgical removal is normally unnecessary.
authors: Department of Ophthalmology, Second Hospital of JiLin University, ChangChun, China.
authors: Bin
authors: B
authors: Fan
authors: Department of Dermatology, Second Hospital of JiLin University, ChangChun, China.
authors: Jin-Feng
authors: JF
authors: Wang
authors: Department of Ophthalmology, Second Hospital of JiLin University, ChangChun, China.
authors: Bin
authors: B
authors: Zheng
authors: Department of Ophthalmology, Second Hospital of JiLin University, ChangChun, China.
authors: Xin-Zhu
authors: XZ
authors: Qi
authors: Department of Ophthalmology, Second Hospital of JiLin University, ChangChun, China.
authors: Jing-Yao
authors: JY
authors: Song
authors: Department of Ophthalmology, Second Hospital of JiLin University, ChangChun, China. Electronic address: liguangyu@aliyun.com.
authors: Guang-Yu
authors: GY
authors: Li
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D000935:Antifungal Agents / Q000627:therapeutic use; D002648:Child; D002675:Child, Preschool; D002681:China; D015821:Eye Infections, Fungal / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005141:Eyelid Diseases / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009281:Naphthalenes / Q000627:therapeutic use; D012189:Retrospective Studies; D013175:Sporothrix / Q000302:isolation & purification*; D013174:Sporotrichosis / Q000175:diagnosis* / Q000188:drug therapy / Q000382:microbiology; D000077291:Terbinafine
chemical_list: D000935:Antifungal Agents; D009281:Naphthalenes; D000077291:Terbinafine