title: Toluene downregulates filaggrin expression via the extracellular signal-regulated kinase and signal transducer and activator of transcription-dependent pathways.
authors: Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, Korea.
authors: Hana
authors: H
authors: Lee
authors: Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, Korea.
authors: Jung Jin
authors: JJ
authors: Shin
authors: Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, Korea.
authors: Hyun Cheol
authors: HC
authors: Bae
authors: Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, Korea.
authors: Woo-In
authors: WI
authors: Ryu
authors: Department of Dermatology and Division of Brain Korea 21 Project for Biomedical Science, Korea University College of Medicine, Seoul, Korea. Electronic address: skin4u@korea.ac.kr.
authors: Sang Wook
authors: SW
authors: Son
mesh_terms: D000393:Air Pollutants / Q000633:toxicity*; D015415:Biomarkers / Q000378:metabolism; D003876:Dermatitis, Atopic / Q000139:chemically induced / Q000378:metabolism; D015536:Down-Regulation; D004817:Epidermis / Q000187:drug effects* / Q000378:metabolism; D000091344:Filaggrin Proteins; D006801:Humans; D007381:Intermediate Filament Proteins / Q000378:metabolism*; D020935:MAP Kinase Signaling System / Q000187:drug effects*; D019950:Mitogen-Activated Protein Kinase 1 / Q000378:metabolism; D048052:Mitogen-Activated Protein Kinase 3 / Q000378:metabolism; D050796:STAT3 Transcription Factor / Q000378:metabolism*; D014050:Toluene / Q000633:toxicity*
chemical_list: D000393:Air Pollutants; D015415:Biomarkers; C000717249:FLG protein, human; D000091344:Filaggrin Proteins; D007381:Intermediate Filament Proteins; D050796:STAT3 Transcription Factor; C494086:STAT3 protein, human; D014050:Toluene; C535150:MAPK1 protein, human; D019950:Mitogen-Activated Protein Kinase 1; D048052:Mitogen-Activated Protein Kinase 3