title: Detection of Zika virus in Brazilian patients during the first five days of infection - urine versus plasma.
abstract: Advantages of testing for Zika virus (ZIKV) in urine have been reported, such as the persistence of ZIKV in this type of specimen for up to 20 days after ZIKV disease onset. We investigate 61 patients in the first 5 days post-symptom onset and find more patients testing positive for ZIKV in plasma samples (n=46), than in corresponding urine samples (n=37). For patients respectively testing positive in both plasma and urine (n=28), respective viral loads appeared similar.
authors: Department of Pathology, Hospital das Clínicas, School of Medicine, University of São Paulo, São Paulo, Brazil.
authors: Rodrigo
authors: R
authors: Pessôa
authors: João Veras
authors: JV
authors: Patriota
authors: Maria de Lourdes
authors: Mde L
authors: de Souza
authors: Ahmed
authors: A
authors: Abd El Wahed
authors: Sabri Saeed
authors: SS
authors: Sanabani
mesh_terms: D000293:Adolescent; D000328:Adult; D000368:Aged; D001938:Brazil; D002648:Child; D002675:Child, Preschool; D005260:Female; D006801:Humans; D008297:Male; D008403:Mass Screening / Q000379:methods*; D008875:Middle Aged; D012367:RNA, Viral / Q000097:blood / Q000302:isolation & purification* / Q000652:urine; D060888:Real-Time Polymerase Chain Reaction; D044967:Serum / Q000821:virology; D013997:Time Factors; D014556:Urine / Q000821:virology; D055815:Young Adult; D000071244:Zika Virus / Q000235:genetics / Q000302:isolation & purification*; D000071243:Zika Virus Infection / Q000175:diagnosis*
chemical_list: D012367:RNA, Viral
keywords: Zika virus; early detection; real-time RT-PCR; urine