title: The prevalence of sarcopenia before and after correction for DXA-derived fat-free adipose tissue.
abstract: The literature suggests that the estimate of lean mass may be overestimated in the obese using dual-energy X-ray absorptiometry (DXA), as ~15% of adipose tissue is composed of fat-free tissue. The purpose of this study was to investigate how the DXA-derived fat-free adipose influences appendicular lean mass and prevalence of sarcopenia across a range of body fat % in both men and women using a national sample (n=1946). The appendicular lean mass/m2went from 7.0 kg/m2(confidence interval (CI): 6.9, 7.2) to 5.9 kg/m2(CI: 5.8, 6.1) following correction in those with ⩾35% body fat, whereas it only went from 7.5 kg/m2(CI: 7.2, 7.8) to 7.1 kg/m2(CI: 6.8, 7.4) following correction in those with <25% body fat. Fat-free adipose tissue may need to be accounted for when estimating appendicular lean mass and failure to account for fat-free adipose tissue may underestimate the prevalence of sarcopenia.
authors: Kevser Ermin Applied Physiology Laboratory, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS, USA.
authors: J P
authors: JP
authors: Loenneke
authors: Center for Health Behavior Research, Department of Health, Exercise Science and Recreation Management, The University of Mississippi, University, MS, USA.
authors: P D
authors: PD
authors: Loprinzi
authors: National Institute of Fitness and Sports in Kanoya, Kanoya, Japan.
authors: T
authors: T
authors: Abe
mesh_terms: D015502:Absorptiometry, Photon / Q000379:methods / Q000706:statistics & numerical data*; D000273:Adipose Tissue / Q000503:physiopathology*; D050154:Adiposity; D000368:Aged; D015992:Body Mass Index; D005260:Female; D006801:Humans; D008297:Male; D008875:Middle Aged; D009749:Nutrition Surveys; D009765:Obesity / Q000150:complications / Q000503:physiopathology*; D015995:Prevalence; D055948:Sarcopenia / Q000175:diagnosis / Q000453:epidemiology* / Q000209:etiology