title: [Radiotherapy for brain metastases].
abstract: Radiotherapy for brain metastases has become more multifaceted. Indeed, with the improvement of the patient's life expectancy, side effects must be undeniably avoided and the retreatments or multiple treatments are common. The cognitive side effects should be warned and the most modern techniques of radiation therapy are used regularly to reach this goal. The new classifications of patients with brain metastases help guiding treatment more appropriately. Stereotactic radiotherapy has supplanted whole brain radiation therapy both for patients with metastases in place and for those who underwent surgery. Hippocampus protection is possible with intensity-modulated radiotherapy. Its relevance in terms of cognitive functioning should be more clearly demonstrated but the requirement, for using it, is increasingly strong. While addressing patients in palliative phase, the treatment of brain metastases is one of the localisations where technical thinking is the most challenging.
authors: Centre régional de radiochirurgie stéréotaxique, CHU Rangueil, avenue Jean-Poulhès, 31052 Toulouse cedex, France; Service de radiothérapie, groupe Oncorad Garonne, clinique Pasteur, « L'Atrium », 1, rue de la Petite-Vitesse, 31300 Toulouse, France.
authors: I
authors: I
authors: Latorzeff
authors: Département universitaire de radiothérapie, centre Paul-Strauss, Unicancer, 3, rue de la Porte-de-l'Hôpital, 67065 Strasbourg, France.
authors: D
authors: D
authors: Antoni
authors: Service de physique médicale, institut de cancérologie de l'Ouest, centre René-Gauducheau, Unicancer, 44805 Saint-Herblain, France.
authors: S
authors: S
authors: Gaudaire-Josset
authors: Service de radiothérapie, CHU Pitié-Salpêtrière, Assistance publique-Hôpitaux de Paris, boulevard de l'Hôpital, 75013 Paris cedex, France.
authors: L
authors: L
authors: Feuvret
authors: Département universitaire de radiothérapie, institut Paoli-Calmette, Unicancer, 232, boulevard de Sainte-Marguerite, 13273 Marseille, France.
authors: A
authors: A
authors: Tallet-Richard
authors: Département universitaire de radiothérapie, centre Georges-François-Leclerc, Unicancer, 1, rue Professeur-Marion, BP 77980, 21079 Dijon cedex, France.
authors: G
authors: G
authors: Truc
authors: Département universitaire de radiothérapie, centre Paul-Strauss, Unicancer, 3, rue de la Porte-de-l'Hôpital, 67065 Strasbourg, France. Electronic address: gnoel@strasbourg.unicancer.fr.
authors: G
authors: G
authors: Noël
mesh_terms: D000367:Age Factors; D001921:Brain / Q000528:radiation effects; D001932:Brain Neoplasms / Q000532:radiotherapy* / Q000556:secondary*; D003072:Cognition Disorders / Q000209:etiology / Q000517:prevention & control; D003131:Combined Modality Therapy; D016371:Cranial Irradiation / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D019583:Dose Fractionation, Radiation; D006801:Humans; D058958:Organs at Risk; D011832:Radiation Injuries / Q000517:prevention & control; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D050397:Radiotherapy, Intensity-Modulated / Q000009:adverse effects / Q000379:methods
keywords: Brain metastasis; Cognition; Hippocampe; Hippocampus; IMRT; Métastases cérébrales; RCMI; Stereotactic; Stéréotaxie