title: Impact of early mobilization and rehabilitation on global functional outcome one year after aneurysmal subarachnoid hemorrhage.
abstract: OBJECTIVE
  To assess the impact of early mobilization and rehabilitation on global functional outcome one year after aneurysmal subarachnoid haemorrhage.
  
  
  METHODS
  Prospective, controlled, interventional study comprising patients managed in the neuro-intermediate ward following repair of a ruptured intracranial aneurysm. Patients in the Control group (n = 76) received standard treatment, whereas those in the Early Rehab group (n = 92) in addition underwent early mobilization and rehabilitation. Demographic, clinical and intervention data were registered. Global functional outcome was assessed using the modified Rankin Scale and the Glasgow Outcome Scale Extended.
  
  
  RESULTS
  The 2 groups were similar in their demographic and clinical characteristics. Early Rehab group patients were mobilized more quickly (p < 0.001), median 1.4 days (range 0-23 days) after aneurysm repair. After 1 year, 47% of the patients had made a good recovery, whereas 6.5% had died. Regression analysis did not reveal any significant effect of early rehabilitation on functional outcome. However, in poor-grade patients, early rehabilitation more than doubled the chance of a favourable outcome (adjusted odds ratio = 2.33; confidence interval 1.04-5.2, p = 0.039).
  
  
  CONCLUSIONS
  Early mobilization and rehabilitation probably increases the chance of a good functional outcome in poor-grade aneurysmal subarachnoid haemorrhage patients.
authors: Dept of Physical Medicine and Rehabilitation, Oslo University Hospital, Ullevaal and Rikshospitalet, P.B. 4950 Nydalen, 0424 Oslo, Norway. tanja.karic@gmail.com.
authors: Tanja
authors: T
authors: Karic
authors: Cecilie
authors: C
authors: Røe
authors: Tonje Haug
authors: TH
authors: Nordenmark
authors: Frank
authors: F
authors: Becker
authors: Angelika
authors: A
authors: Sorteberg
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D017542:Aneurysm, Ruptured / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery; D004185:Disability Evaluation; D004434:Early Ambulation / Q000379:methods*; D005260:Female; D023261:Glasgow Outcome Scale; D006801:Humans; D002532:Intracranial Aneurysm / Q000503:physiopathology / Q000534:rehabilitation / Q000601:surgery; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D020127:Recovery of Function; D013345:Subarachnoid Hemorrhage / Q000503:physiopathology* / Q000534:rehabilitation / Q000601:surgery; D013997:Time Factors; D016896:Treatment Outcome