title: Simultaneous analysis 26 mineral element contents from highly consumed cultured chicken overexposed to arsenic trioxide by inductively coupled plasma mass spectrometry.
abstract: This study assessed the impacts of dietary arsenic trioxide (As2O3) on 26 mineral element contents in the liver and kidney of chicken. A total of 100 male Hy-line cocks were randomly divided into 2 groups (50 chickens in each group), including an arsenic-treated group (basic diet supplemented with As2O3at 30 mg/kg) and a control group (basal diet). The feeding experiment lasted for 90 days and the experimental animals were given free access to feed and water. We determined 26 mineral elements in the liver and kidney by inductively coupled plasma mass spectrometry (ICP-MS). The results showed that nine element levels (Al, Mn, Co, Cu, Zn, Se, Cd, Ba, and Pb) were significantly decreased (P < 0.05) in the liver of chickens exposed to As2O3compared to the control chickens where three element levels (Ni, As, and Hg) increased significantly (P < 0.05). The results in the kidney showed that nine element levels (Al, K, Ca, Cr, Mn, Ni, Sb, Ba, and Pb) were significantly decreased (P < 0.05) in the chickens exposed to As2O3compared to the control chickens where four element levels (Mo, As, Cd, and Hg) increased significantly (P < 0.05). These results suggest that supplementation of high levels of arsenic affected trace mineral levels in the liver and kidney of chicken, and the effects vary from organ to organ. The aim of this study is to provide references for further study of heavy metal poisoning by detecting the contents of minerals induced by arsenic in chicken.
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China.
authors: Ying
authors: Y
authors: He
authors: Department of Chemical Engineering and Bioengineering, McMaster University, 1280 Main Street West, Hamilton, ON, L8S4L8, Canada.
authors: Bonan
authors: B
authors: Sun
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China.
authors: Siwen
authors: S
authors: Li
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China.
authors: Xiao
authors: X
authors: Sun
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China.
authors: Ying
authors: Y
authors: Guo
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China.
authors: Hongjing
authors: H
authors: Zhao
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China.
authors: Yu
authors: Y
authors: Wang
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China. jgshun@126.com.
authors: Guangshun
authors: G
authors: Jiang
authors: College of Wildlife Resource, Northeast Forestry University, PRC, 26 Hexing Rd, Xiangfang District, Harbin, 150040, People's Republic of China. xingmingwei@nefu.edu.cn.
authors: Mingwei
authors: M
authors: Xing
mesh_terms: D000821:Animal Feed / Q000032:analysis / Q000633:toxicity; D000818:Animals; D000077237:Arsenic Trioxide; D001152:Arsenicals / Q000032:analysis; D002645:Chickens; D007668:Kidney / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D008099:Liver / Q000737:chemistry / Q000187:drug effects / Q000378:metabolism; D013058:Mass Spectrometry / Q000379:methods*; D010087:Oxides / Q000032:analysis / Q000633:toxicity; D011897:Random Allocation
chemical_list: D001152:Arsenicals; D010087:Oxides; D000077237:Arsenic Trioxide
keywords: Arsenic trioxide; Chicken; ICP-MS; Kidney; Liver; Mineral levels