title: Feasibility of free-breathing dynamic contrast-enhanced MRI of the abdomen: a comparison between CAIPIRINHA-VIBE, Radial-VIBE with KWIC reconstruction and conventional VIBE.
abstract: OBJECTIVE
  To evaluate the feasibilities of controlled aliasing in parallel imaging results in higher acceleration with volumetric interpolated breath-hold examination (CAIPIRINHA-VIBE), radial acquisition of VIBE (Radial-VIBE) with k-space-weighted image contrast (KWIC) reconstruction (KWIC-Radial-VIBE) and conventional-VIBE (c-VIBE) for free-breathing dynamic contrast-enhanced (DCE)-MRI of the abdomen.
  
  
  METHODS
  23 prospectively enrolled patients underwent DCE-MRI of the abdomen with CAIPIRINHA-VIBE (n = 10), KWIC-Radial-VIBE (n = 6) or c-VIBE (n = 7). Qualitative image quality of the DCE-MR images and perfusion maps was independently scored by two abdominal radiologists using a 5-point scale (from 1, uninterpretable, to 5, very good). For quantitative analysis, the signal-to-noise ratio (SNR) of the liver and goodness-of-fit (GOF) of the time-intensity curve were measured.
  
  
  RESULTS
  In the three tested sequences, DCE-MRI had good temporal (5 s) and spatial resolution (1.48 × 1.48 × 4 mm/voxel). Interobserver agreement in the qualitative analysis was good (ĸ = 0.753; 95% confidence interval, 0.610-0.895). Therefore, the mean scores were used in the data analysis. Overall image quality was comparable between CAIPIRINHA-VIBE (3.52 ± 0.55) and KWIC-Radial-VIBE (3.72 ± 0.37; p = 1.000), and both were significantly better than c-VIBE (2.71 ± 0.34; p < 0.001). Perfusion map quality score was highest with KWIC-Radial-VIBE (4.33 ± 0.65), followed by CAIPIRINHA-VIBE (3.70 ± 0.73) and c-VIBE (3.14 ± 0.66), but without statistical significance between CAIPIRINHA-VIBE and KWIC-Radial-VIBE (p = 0.167). The SNR of the liver and GOF of the time-intensity curve did not significantly differ between the three sequences (p = 0.116 and 0.224, respectively).
  
  
  CONCLUSIONS
  CAIPIRINHA-VIBE and KWIC-Radial-VIBE provide comparably better performance than c-VIBE. Both can be feasible sequences with acceptable good image quality for free-breathing DCE-MRI.
  
  
  CONCLUSIONS
  CAIPIRINHA-VIBE and KWIC-Radial-VIBE provide comparably better quality of free-breathing DCE-MRIs than c-VIBE.
authors: 1 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.|2 Department of Radiology, Yonsei University College of Medicine, Severance Hospital, Seoul, Republic of Korea.
authors: Nieun
authors: N
authors: Seo
authors: 3 Department of Oncology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors: Seong J
authors: SJ
authors: Park
authors: 4 Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea.
authors: Bohyun
authors: B
authors: Kim
authors: 1 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors: Chang K
authors: CK
authors: Lee
authors: 1 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors: Jimi
authors: J
authors: Huh
authors: 1 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors: Jeong K
authors: JK
authors: Kim
authors: 1 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors: Seung S
authors: SS
authors: Lee
authors: 5 Siemens Healthcare Korea, Seoul, Republic of Korea.
authors: In S
authors: IS
authors: Kim
authors: 6 MR Application Predevelopment, Siemens Healthcare, Erlangen, Germany.
authors: Dominik
authors: D
authors: Nickel
authors: 1 Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
authors: Kyung W
authors: KW
authors: Kim
mesh_terms: D000005:Abdomen; D003287:Contrast Media; D005240:Feasibility Studies; D005260:Female; D006801:Humans; D007089:Image Enhancement / Q000379:methods; D007090:Image Interpretation, Computer-Assisted / Q000379:methods*; D008279:Magnetic Resonance Imaging / Q000379:methods*; D008297:Male; D008875:Middle Aged; D011446:Prospective Studies; D059629:Signal-To-Noise Ratio
chemical_list: D003287:Contrast Media