title: Frontotemporal Dementia: An Updated Clinician's Guide.
abstract: Today, frontotemporal dementia (FTD) remains one of the most common forms of early-onset dementia, that is, before the age of 65, thus posing several diagnostic challenges to clinicians since symptoms are often mistaken for psychiatric or neurological diseases causing a delay in correct diagnosis, and the majority of patients with FTD present with symptoms at ages between 50 and 60. Genetic components are established risk factors for FTD, but the influence of lifestyle, comorbidity, and environmental factors on the risk of FTD is still unclear. Approximately 40% of individuals with FTD have a family history of dementia but less than 10% have a clear autosomal dominant pattern of inheritance. Lack of insight is often an early clue to FTD. A tailored treatment option at an early phase can mitigate suffering and improve patients' and caregivers' quality of life.
authors: Lovisenberg Diaconal University College, Oslo, Norway rosness@gmail.com.
authors: Tor Atle
authors: TA
authors: Rosness
authors: Norwegian National Advisory Unit on Ageing and Health, Tønsberg, Norway.
authors: Knut
authors: K
authors: Engedal
authors: Department of Neurology and Psychiatry, Neuropsychiatry Clinics, Massachusetts General Hospital, Boston, MA, USA Department of Psychiatry, Neuropsychiatry Clinics, Massachusetts General Hospital, Boston, MA, USA Harvard Medical School, Boston, MA, USA.
authors: Zeina
authors: Z
authors: Chemali
mesh_terms: D017668:Age of Onset; D001526:Behavioral Symptoms / Q000209:etiology*; D003072:Cognition Disorders / Q000175:diagnosis / Q000209:etiology*; D005260:Female; D057180:Frontotemporal Dementia / Q000150:complications / Q000175:diagnosis* / Q000235:genetics / Q000523:psychology; D020022:Genetic Predisposition to Disease; D006801:Humans; D008297:Male; D008875:Middle Aged; D009483:Neuropsychological Tests; D017410:Practice Guidelines as Topic; D012307:Risk Factors
keywords: dementia; early-onset dementia; frontotemporal dementia