title: Two Decades of Laccases: Advancing Sustainability in the Chemical Industry.
abstract: Given the current state of environmental affairs and that our future on this planet as we know it is in jeopardy, research and development into greener and more sustainable technologies within the chemical and forest products industries is at its peak. Given the global scale of these industries, the need for environmentally benign practices is propelling new green processes. These challenges are also impacting academic research and our reagents of interest are laccases. These enzymes are employed in a variety of biotechnological applications due to their native function as catalytic oxidants. They are about as green as it gets when it comes to chemical processes, requiring O2as their only co-substrate and producing H2O as the sole by-product. The following account will review our twenty year journey on the use of these enzymes within our research group, from their initial use in biobleaching of kraft pulps and for fiber modification within the pulp and paper industry, to their current application as green catalytic oxidants in the field of synthetic organic chemistry.
authors: Renewable Bioproducts Institute, School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.|Joint Institute for Biological Sciences, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
authors: Mark D
authors: MD
authors: Cannatelli
authors: Renewable Bioproducts Institute, School of Chemistry & Biochemistry, Georgia Institute of Technology, Atlanta, GA 30332, USA.|Joint Institute for Biological Sciences, Biosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.|Department of Chemical & Biomolecular Engineering, Department of Forestry, Wildlife & Fisheries, University of Tennessee, Knoxville, TN 37996, USA.
authors: Arthur J
authors: AJ
authors: Ragauskas
mesh_terms: D002384:Catalysis; D002617:Chemical Industry; D042845:Laccase / Q000737:chemistry*; D010084:Oxidation-Reduction; D010100:Oxygen / Q000737:chemistry; D011487:Protein Conformation
chemical_list: D042845:Laccase; D010100:Oxygen
keywords: Biotechnology; green chemistry; laccases; organic synthesis; sustainability