title: High frequency of metabolic syndrome in adult Zoroastrians in Yazd, Iran: a cross-sectional study.
abstract: BACKGROUND
  Metabolic syndrome (MS) is a cluster of metabolic disturbances, and its prevalence is increasing worldwide. MS exhibits variations among ethnic groups. Zoroastrianism is an ethnic minority which has maintained its isolation and endogamy up to now. So, we evaluated the frequency of MS in Zoroastrians of Yazd, Iran.
  
  
  METHODS
  In this cross-sectional study, participants aged ≥30 years were selected using a systematic random sampling. Weight, height, body mass index (BMI), waist circumference (WC), hip circumference (HC), waistto- hip ratio (WHR) and blood pressure (BP) were measured using standard methods. Also, blood levels of glucose, triglycerides (TG), total cholesterol, high-density lipoprotein (HDL), low-density lipoprotein (LDL), urea, creatinine and uric acid (UA) were measured. Both revised National Cholesterol Education Program Adult Treatment Panel III (ATPIII) and Joint Interim Statement (JIS) criteria were used to diagnose the MS.
  
  
  RESULTS
  The mean±SD age of the participants (n=403) was 56.9±12.8 years. The frequency of MS was 69.7% and 74.9% based on JIS and ATPIII criteria, respectively; this was significantly different by age, marital status, job, educational level, and menopausal status (p<0.05). The most prevalent abnormal parameters of MS according to ATPIII and JIS criteria were high WC (95%) and low HDL (87.9%), respectively. Mean LDL, systolic BP, WHR, UA, urea, and creatinine were different between men and women. The difference between the age groups was statistically significant for BMI, systolic BP, diastolic BP, TG, WHR and urea (p<0.05).
  
  
  CONCLUSIONS
  This study showed a high frequency of MS in Zoroastrians of Yazd, Iran.
authors: MD, Medical Scientific Association, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. hosain.afrand@yahoo.com.
authors: Mohammadhosain
authors: M
authors: Afrand
authors: Assistant Professor, Department of Endocrinology, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. s_h_khalilzadeh@yahoo.com.
authors: Saeed Hossein
authors: SH
authors: Khalilzadeh
authors: MD, Researcher, Industrial Diseases Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. dr.shojaaddiny@gmail.com.
authors: Ahmad
authors: A
authors: Shojaoddiny-Ardekani
authors: Professor, Department of Endocrinology, Yazd Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. afkhamiam@yahoo.com.
authors: Mohammad
authors: M
authors: Afkhami-Ardekani
authors: Department of Nursing and Midwifery, Shahid Sadoughi University of Medical Sciences, Yazd, Iran. aryaee.azita@yahoo.com.
authors: Azita
authors: A
authors: Ariaeinejad
keywords: Frequency; Metabolic syndrome; Minority; Zoroastrian