title: Management of locoregional recurrence in cutaneous squamous cell carcinoma of the head and neck.
abstract: Cutaneous squamous cell carcinomas often affect elderly patients. Follow-up monitoring is difficult in these patients due to their multi-morbidity and reduced compliance. Tumour recurrence is consequently diagnosed in advanced tumour stages. Surgical therapy with curative intention often requires extended resections. The study at hand should determine whether surgical concepts are warranted in this collective. Sixty-seven patients who underwent surgical procedure due to recurrent disease of cutaneous head and neck squamous cell carcinoma were included. The cohort was divided in patients with/without adjuvant therapeutic regimens. Data were assessed retrospectively. Complete tumour resection was achieved in 85 % of our patients. Patients with adjuvant treatment demonstrated a favorable 5-year-recurrence-free interval (78 vs 30 %) and overall survival (79 vs 46 %). Complete surgical resection of advanced recurrent head and neck cutaneous squamous cell carcinomas is possible and yields favorable results in terms of survival, especially if combined with adjuvant treatment.
authors: Otorhinolaryngology/Head and Neck Surgery, Klinikum Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany. u.strassen@lrz.tum.de.
authors: Ulrich
authors: U
authors: Strassen
authors: Otorhinolaryngology/Head and Neck Surgery, Klinikum Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.
authors: Benedikt
authors: B
authors: Hofauer
authors: Otorhinolaryngology/Head and Neck Surgery, Klinikum Großhadern, Munich, Germany.
authors: Christian
authors: C
authors: Jacobi
authors: Otorhinolaryngology/Head and Neck Surgery, Klinikum Rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany.
authors: Andreas
authors: A
authors: Knopf
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D002294:Carcinoma, Squamous Cell / Q000473:pathology / Q000601:surgery*; D005260:Female; D006258:Head and Neck Neoplasms / Q000473:pathology / Q000601:surgery*; D006801:Humans; D008297:Male; D009364:Neoplasm Recurrence, Local / Q000473:pathology / Q000601:surgery*; D018714:Radiotherapy, Adjuvant; D012189:Retrospective Studies; D012878:Skin Neoplasms / Q000473:pathology / Q000601:surgery*; D000077195:Squamous Cell Carcinoma of Head and Neck; D016896:Treatment Outcome
keywords: Cutaneous squamous cell carcinoma; Head and neck; Outcome; Recurrence; Therapy