title: [THE DEVELOPMENT OF IMMUNE ENZYME AND IMMUNE CHROMATOGRAPHIC MONOCLONAL TEST-SYSTEM FOR DETECTING TULAREMIA AGENT].
abstract: The immune enzyme and immunochromatographic test-systems for detecting tularemia agent were developed on the basis of selected set of monoclonal antibodies having immunochemical activity to antigens Francisella tularensis. The evaluation of sensitivity and specificity of developed test-systems demonstrated that samples provided detection of strains of F. tularensis in concentration from 5.0 x 105 mkxcm-3 to 1.0 x 106 mkxcm-3 and gave no false positive results in analysis of heterologous microorganisms in concentration of 1.0 x 108 mkxcm-3.
authors: A V
authors: AV
authors: Eremkin
authors: G D
authors: GD
authors: Elagin
authors: D V
authors: DV
authors: Petchenkin
authors: O O
authors: OO
authors: Fomenkov
authors: N V
authors: NV
authors: Bogatcheva
authors: A A
authors: AA
authors: Kitmanov
authors: G V
authors: GV
authors: Kuklina
authors: O V
authors: OV
authors: Tikhvinskaya
mesh_terms: D000818:Animals; D000907:Antibodies, Bacterial / Q000737:chemistry*; D058846:Antibodies, Monoclonal, Murine-Derived / Q000737:chemistry*; D002846:Chromatography, Affinity / Q000379:methods*; D004797:Enzyme-Linked Immunosorbent Assay / Q000379:methods; D005604:Francisella tularensis; D006801:Humans; D051379:Mice; D012680:Sensitivity and Specificity; D014406:Tularemia / Q000175:diagnosis*
chemical_list: D000907:Antibodies, Bacterial; D058846:Antibodies, Monoclonal, Murine-Derived