title: Supramolecular Metallo-Bioadhesive for Minimally Invasive Use.
abstract: A novel metallo-bioadhesive to be used as tissue sealant in minimally invasive procedures is reported. Metal complexation can be used to render gelatin derivatives adhesive, which occurs in minutes, is efficient, and fully biodegradable within weeks.
authors: Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA.
authors: Seonki
authors: S
authors: Hong
authors: Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA.
authors: David
authors: D
authors: Pirovich
authors: Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA.|Division of Interventional Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA.
authors: Aoife
authors: A
authors: Kilcoyne
authors: Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA.
authors: Chen-Han
authors: CH
authors: Huang
authors: Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA.
authors: Hakho
authors: H
authors: Lee
authors: Center for Systems Biology, Massachusetts General Hospital, 185 Cambridge St., CPZN 5206, Boston, MA, 02114, USA. rweissleder@mgh.harvard.edu.|Division of Interventional Radiology, Massachusetts General Hospital, 55 Fruit St., Boston, MA, 02114, USA. rweissleder@mgh.harvard.edu.|Department of Systems Biology, Harvard Medical School, 200 Longwood Ave., Boston, MA, 02115, USA. rweissleder@mgh.harvard.edu.
authors: Ralph
authors: R
authors: Weissleder
mesh_terms: D005780:Gelatin; D014014:Tissue Adhesives
chemical_list: D014014:Tissue Adhesives; D005780:Gelatin
keywords: catechol-conjugated polymers; image-guided intervention; metal-ligand complexation; sealants; surgery; tissue adhesives