title: One-step synthesis of soy protein/graphene nanocomposites and their application in photothermal therapy.
abstract: Photothermal therapy, due to its security and effectiveness, has recently become a promising cancer treatment after surgery, radiotherapy, chemotherapy, and biological therapy. In this article, soy protein isolate/reduced graphene oxide (SPI/rGO) nanocomposites are prepared via a simple and green process. That is, GO is reduced in situ and stabilized by SPI, an abundant, low-cost, sustainable natural material, and simultaneously forms SPI/rGO nanocomposites. The resulting SPI/rGO nanocomposites disperse in water very well and exhibit good biocompatibility due to the attachment of SPI to the surface of rGO. Such SPI/rGO nanocomposites demonstrate an excellent photothermal capacity and are able to kill HeLa cells efficiently with near-infrared irradiation (808nm). The results in this work suggest that such a SPI/rGO hybrid material could be a promising candidate for future applications of photothermal therapy.
authors: State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Polymers and Polymer Composite Materials, Department of Macromolecular Science, Laboratory of Advanced Materials, Fudan University, Shanghai 200433, People's Republic of China.
authors: Xuejiao
authors: X
authors: Jiang
authors: State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Polymers and Polymer Composite Materials, Department of Macromolecular Science, Laboratory of Advanced Materials, Fudan University, Shanghai 200433, People's Republic of China.
authors: Zhao
authors: Z
authors: Li
authors: State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Polymers and Polymer Composite Materials, Department of Macromolecular Science, Laboratory of Advanced Materials, Fudan University, Shanghai 200433, People's Republic of China.
authors: Jinrong
authors: J
authors: Yao
authors: State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Polymers and Polymer Composite Materials, Department of Macromolecular Science, Laboratory of Advanced Materials, Fudan University, Shanghai 200433, People's Republic of China.
authors: Zhengzhong
authors: Z
authors: Shao
authors: State Key Laboratory of Molecular Engineering of Polymers, Collaborative Innovation Center of Polymers and Polymer Composite Materials, Department of Macromolecular Science, Laboratory of Advanced Materials, Fudan University, Shanghai 200433, People's Republic of China. Electronic address: chenx@fudan.edu.cn.
authors: Xin
authors: X
authors: Chen
mesh_terms: D006108:Graphite / Q000737:chemistry / Q000494:pharmacology; D006367:HeLa Cells; D006801:Humans; D006979:Hyperthermia, Induced / Q000379:methods*; D053761:Nanocomposites / Q000737:chemistry*; D009369:Neoplasms / Q000378:metabolism / Q000473:pathology / Q000628:therapy*; D010789:Phototherapy / Q000379:methods*; D030262:Soybean Proteins / Q000737:chemistry / Q000494:pharmacology
chemical_list: D030262:Soybean Proteins; D006108:Graphite
keywords: Biocompatibility; Carbon materials; Hybrid materials; Photothermal transformation; Plant proteins