title: Removing Cardiac Artefacts in Magnetoencephalography with Resampled Moving Average Subtraction.
abstract: Magnetoencephalography (MEG) signals are commonly contaminated by cardiac artefacts (CAs). Principle component analysis and independent component analysis have been widely used for removing CAs, but they typically require a complex procedure for the identification of CA-related components. We propose a simple and efficient method, resampled moving average subtraction (RMAS), to remove CAs from MEG data. Based on an electrocardiogram (ECG) channel, a template for each cardiac cycle was estimated by a weighted average of epochs of MEG data over consecutive cardiac cycles, combined with a resampling technique for accurate alignment of the time waveforms. The template was subtracted from the corresponding epoch of the MEG data. The resampling reduced distortions due to asynchrony between the cardiac cycle and the MEG sampling times. The RMAS method successfully suppressed CAs while preserving both event-related responses and high-frequency (>45 Hz) components in the MEG data.
authors: Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA. liminsun@nmr.mgh.harvard.edu.|Division of Newborn Medicine, Department of Medicine, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. liminsun@nmr.mgh.harvard.edu.
authors: Limin
authors: 0000-0002-2004-0777
authors: L
authors: Sun
authors: Department of Radiology, Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, 02129, USA.
authors: Seppo P
authors: SP
authors: Ahlfors
authors: Department of Neurology, Otto-von-Guericke University, Leipziger Straße 44, 39120, Magdeburg, Germany.|Department of Behavioural Neurology, Leibniz Institute of Neurobiology (LIN), Magdeburg, Germany.|Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Magdeburg, Germany.|Forschungscampus STIMULATE, Magdeburg, Germany.
authors: Hermann
authors: H
authors: Hinrichs
mesh_terms: D000328:Adult; D016477:Artifacts; D001921:Brain / Q000502:physiology*; D004562:Electrocardiography / Q000379:methods*; D005260:Female; D064368:Healthy Volunteers; D006801:Humans; D015225:Magnetoencephalography / Q000379:methods*; D008297:Male; D025341:Principal Component Analysis; D013382:Subtraction Technique; D055815:Young Adult
keywords: Cardiac artefact; MEG; Moving average subtraction; Resampling