title: Application of Deep Eutectic Solvent Modified Cotton as a Sorbent for Online Solid-Phase Extraction and Determination of Trace Amounts of Copper and Nickel in Water and Biological Samples.
abstract: Deep eutectic solvent (DES) was used as the extractant to improve the extraction properties of cotton. DES of choline chloride-urea (ChCl-urea) was prepared and immobilized on the surface of cotton fibers. The resulting sorbent was packed on a microcolumn, and a flow injection flame atomic absorption spectrometry was designed for the online separation and determination of trace amounts of copper and nickel. Various parameters affecting the extraction recovery of analytes such as pH, sample volume, sample loading rate, nature, volume, concentration, and flow rate of eluent were investigated and optimized. Under the optimum conditions, the method showed good linearity in the concentration range of 0.25-50.0 and 4.0-125.0 μg L-1with the coefficient of determination (r2) of 0.9991 and 0.9990 for copper and nickel, respectively. The method was very sensitive with the detection limits (defined as 3Sb/m) of 0.05 and 0.60 μg L-1for Cu and Ni, respectively. It was successfully applied for the determination of Cu and Ni in water and biological samples. The accuracy of the method was evaluated through the recovery experiments and independent analysis by electrothermal atomic absorption spectrometry.
authors: Department of Chemistry, Faculty of Science, Yazd University, Yazd, 89195-741, Iran.
authors: Mehdi
authors: M
authors: Karimi
authors: Department of Chemistry, Faculty of Science, Yazd University, Yazd, 89195-741, Iran. sdadfarnia@yazd.ac.ir.
authors: Shayessteh
authors: S
authors: Dadfarnia
authors: Department of Chemistry, Faculty of Science, Yazd University, Yazd, 89195-741, Iran.
authors: Ali Mohammad Haji
authors: AM
authors: Shabani
mesh_terms: D065966:Absorption, Physicochemical; D003300:Copper / Q000032:analysis* / Q000097:blood / Q000652:urine; D032561:Cotton Fiber; D006801:Humans; D006863:Hydrogen-Ion Concentration; D008855:Microscopy, Electron, Scanning; D009532:Nickel / Q000032:analysis* / Q000097:blood / Q000652:urine; D015203:Reproducibility of Results; D052616:Solid Phase Extraction / Q000295:instrumentation / Q000379:methods*; D012997:Solvents / Q000737:chemistry*; D013054:Spectrophotometry, Atomic; D014867:Water / Q000737:chemistry*
chemical_list: D012997:Solvents; D014867:Water; D003300:Copper; D009532:Nickel
keywords: Copper; Cotton; Deep eutectic solvent; Nickel; Online solid-phase extraction