title: Pd-Catalyzed oxidative isomerization of propargylic acetates: highly efficient access to α-acetoxyenones via alkenyl Csp(2)-O bond-forming reductive elimination from Pd(IV).
abstract: A Pd(ii)/(iv)-catalyzed oxidative isomerization of propargylic acetates developed for the synthesis of polysubstituted alkenyl acetates is described. The reductive elimination of alkenyl Csp(2)-OAc bonds from Pd(IV) intermediates is achieved. Mechanistic studies indicate that the reaction mechanism consists of trans acetoxypalladation of a triple bond, isomerization, oxidative addition with PhI(OAc)2 and alkenyl C-OAc bond reductive elimination.
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Jun
authors: J
authors: Li
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Wenjie
authors: W
authors: Yang
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Fachao
authors: F
authors: Yan
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Qing
authors: Q
authors: Liu
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Ping
authors: P
authors: Wang
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Yueyun
authors: Y
authors: Li
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Yi
authors: Y
authors: Zhao
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com.
authors: Yunhui
authors: Y
authors: Dong
authors: School of Chemical Engineering, Shandong University of Technology, 266 West Xincun Road, Zibo 255049, P. R. China. huiliu1030@sdut.edu.cn dyh651118@126.com and College of Materials Science and Engineering, Hunan University, Changsha, Hunan 410082, China.
authors: Hui
authors: H
authors: Liu