title: Predictive Factors for Excellent or Extremely Poor Functional Outcome in Initial Atrial Fibrillation-Related Cardioembolic Stroke.
abstract: We aimed to determine the predictive factors for excellent or extremely poor functional outcome in patients with first-ever atrial fibrillation (AF)-related cardioembolic stroke.
  
  
  
  Retrospective observational study from a database. Patients with AF-related cardioembolic stroke with a premorbid modified Rankin Scale (mRS) score of 0 or 1 and without a previous history of stroke were included.
  
  
  
  Factors associated with excellent functional outcome (mRS scores of 0 or 1; n = 77; 30.4% of patients) included age >78 years (OR 0.31, 95% CI 0.15-0.61), male sex (OR 2.16, 95% CI 1.04-4.60), absence of hypertension (OR 0.46, 95% CI 0.22-0.94) and initial National Institutes of Health Stroke Scale (NIHSS) score of >9 (OR 0.08, 95% CI 0.03-0.16). Factors associated with extremely poor functional outcome (mRS scores of 5 or 6; n = 63; 24.9%) included age >78 years (OR 3.30, 95% CI 1.54-7.39), initial NIHSS score of >9 (OR 12.38, 95% CI 5.40-32.56), congestive heart failure (OR 4.82, 95% CI 2.00-12.19) and ischemic heart disease (OR 4.02, 95% CI 1.18-14.69).
  
  
  
  Predictive factors exist to delineate excellent and extremely poor functional outcomes after a first-time stroke associated with AF.
authors: Department of Neurology, Saiseikai Fukuoka General Hospital, Kyushu University, Fukuoka, Japan.
authors: Koji
authors: K
authors: Tanaka
authors: Takeshi
authors: T
authors: Yamada
authors: Takako
authors: T
authors: Torii
authors: Shoji
authors: S
authors: Matsumoto
authors: Takeo
authors: T
authors: Yoshimura
authors: Kei-Ichiro
authors: KI
authors: Takase
authors: Yoshifumi
authors: Y
authors: Wakata
authors: Naoki
authors: N
authors: Nakashima
authors: Jun-Ichi
authors: JI
authors: Kira
authors: Hiroyuki
authors: H
authors: Murai
mesh_terms: D000203:Activities of Daily Living / Q000145:classification*; D000368:Aged; D000369:Aged, 80 and over; D001281:Atrial Fibrillation / Q000150:complications* / Q000628:therapy*; D003952:Diagnostic Imaging; D004185:Disability Evaluation; D005260:Female; D006801:Humans; D006973:Hypertension / Q000150:complications; D020766:Intracranial Embolism / Q000145:classification / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D002546:Ischemic Attack, Transient / Q000145:classification / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy; D008297:Male; D008875:Middle Aged; D009460:Neurologic Examination; D017063:Outcome Assessment, Health Care; D011379:Prognosis; D011446:Prospective Studies; D012189:Retrospective Studies; D012307:Risk Factors; D020521:Stroke / Q000145:classification / Q000150:complications / Q000175:diagnosis* / Q000209:etiology* / Q000628:therapy