title: Nodular Cutaneous Amyloidosis at the Temple.
abstract: A 52-year-old woman presented with a large partially yellow and erythematous tumor on her right temple. She reported that it had grown over the last 4 years. Regional lymph nodes were impalpable. A punch biopsy showed eosinophilic material in the dermis and subcutis. Immunohistochemistry showed positive staining for kappa and lambda light chains. Electron microscopy showed the typical amyloid fibrils (7-10 nm in diameter). There was no evidence of systemic amyloidosis, paraproteinemia or underlying plasmacytoma. The tumor was completely removed via curettage. At follow-up, the patient presented in good health with no signs of relapse.
authors: Department of Dermatology, University Medical Center Regensburg, Regensburg, Germany.
authors: Kathrin
authors: K
authors: Schucht
authors: Institute of Pathology, University of Regensburg, Regensburg, Germany.
authors: Josef
authors: J
authors: Schröder
authors: Institute of Pathology, University of Regensburg, Regensburg, Germany.
authors: Heiko
authors: H
authors: Siegmund
authors: Institute of Pathology, University of Regensburg, Regensburg, Germany.
authors: Claudia
authors: C
authors: Grafe
authors: Department of Dermatology, University Medical Center Regensburg, Regensburg, Germany.
authors: Stephan
authors: S
authors: Schreml
keywords: Amyloid; Amyloidosis; Primary localized cutaneous nodular amyloidosis