title: Au nanorods modulated NIR fluorescence and singlet oxygen generation of water soluble dendritic zinc phthalocyanine.
abstract: A novel cyano-terminated zinc phthalocyanine (ZnPc-CN) exhibiting visible near infrared (vis-NIR) emitting around 690nm in N,N-dimethylformamide (DMF) solvent has been synthesized. Furthermore, the peripheral cyano groups of newly synthesized zinc phthalocyanine were hydrolyzed in strong basic solution, leading to water soluble carboxylated zinc phthalocyanine (ZnPc-COOH) with completely quenched fluorescence in aqueous solution. Interestingly, we found that the NIR fluorescence of aqueous ZnPc-COOH was dramatically recovered in the presence of gold nanorods (Au NR), which was due to the alternation of ZnPc-COOH molecules self-assembling via electrostatic interaction between cetyltrimethylammonium bromide (CTAB) on the surface of Au NR and peripheral carboxyl of ZnPc-COOH. In addition, ZnPc-COOH/Au NR conjugates demonstrated an improved singlet oxygen generation, which could be served as potential bioimaging probe and photosensitizer for photodynamic therapy.
authors: Research Branch of Advanced Functional Materials, School of Microelectronics and Solid-State Electronics, University of Electronic Science and Technology of China, Chengdu 610054, PR China.
authors: Xuefei
authors: X
authors: Zhou
authors: Research Branch of Advanced Functional Materials, School of Microelectronics and Solid-State Electronics, University of Electronic Science and Technology of China, Chengdu 610054, PR China.
authors: Xiaohong
authors: X
authors: He
authors: Research Branch of Advanced Functional Materials, School of Microelectronics and Solid-State Electronics, University of Electronic Science and Technology of China, Chengdu 610054, PR China.
authors: Shiliang
authors: S
authors: Wei
authors: Research Branch of Advanced Functional Materials, School of Microelectronics and Solid-State Electronics, University of Electronic Science and Technology of China, Chengdu 610054, PR China. Electronic address: jiakun@uestc.edu.cn.
authors: Kun
authors: K
authors: Jia
authors: Research Branch of Advanced Functional Materials, School of Microelectronics and Solid-State Electronics, University of Electronic Science and Technology of China, Chengdu 610054, PR China. Electronic address: liuxb@uestc.edu.cn.
authors: Xiaobo
authors: X
authors: Liu
mesh_terms: D000077286:Cetrimonium; D002593:Cetrimonium Compounds / Q000737:chemistry; D004126:Dimethylformamide / Q000737:chemistry; D005453:Fluorescence; D006046:Gold / Q000737:chemistry*; D006868:Hydrolysis; D007211:Indoles / Q000138:chemical synthesis*; D007259:Infrared Rays; D054833:Isoindoles; D043942:Nanotubes / Q000737:chemistry* / Q000648:ultrastructure; D009942:Organometallic Compounds / Q000138:chemical synthesis*; D017319:Photosensitizing Agents / Q000138:chemical synthesis*; D026082:Singlet Oxygen / Q000737:chemistry*; D012996:Solutions; D055672:Static Electricity; D014867:Water; D017967:Zinc Compounds
chemical_list: D002593:Cetrimonium Compounds; D007211:Indoles; D054833:Isoindoles; D009942:Organometallic Compounds; D017319:Photosensitizing Agents; D012996:Solutions; D017967:Zinc Compounds; D014867:Water; C052159:Zn(II)-phthalocyanine; D026082:Singlet Oxygen; D006046:Gold; D004126:Dimethylformamide; D000077286:Cetrimonium
keywords: Gold nanorods; NIR fluorophores; Plasmonics; Self-assembling; Zinc phthalocyanine