title: [DYNAMICS OF METABOLIC CHARACTERISTICS, MARKERS OF OXIDATIVE STRESS AND VASCULAR WALL DAMAGE DURING TREATMENT OF OBESE PRE-DIABETIC PATIENTS].
abstract: We studied lipid and carbohydrate metabolism, markers of oxidative stress (plasma malonic dialdehyde and dienoic conjugates) and vascular wall damage (CRP microalbuminuria, blood desquamated endotheliocytes) before and after 12 week treatment of obese pre-diabetic patients. The study showed positive dynamics of the above metabolic parameters with normalization of carbohydrate metabolism in 60% of the patients and angioprotective effect of prescribed therapy. The proposed treatment can be used to prevent diabetes mellitus.
authors: L A
authors: LA
authors: Romanenko
authors: Polyatykina T S
authors: N V
authors: NV
authors: Mavrycheva
authors: N V
authors: NV
authors: Budnikova
authors: V B
authors: VB
authors: Grinshtein
mesh_terms: D000328:Adult; D000419:Albuminuria / Q000378:metabolism; D000975:Antioxidants / Q000627:therapeutic use*; D015415:Biomarkers / Q000378:metabolism; D050260:Carbohydrate Metabolism / Q000187:drug effects; D003131:Combined Modality Therapy / Q000379:methods*; D004035:Diet Therapy / Q000379:methods; D019468:Disease Management; D042783:Endothelial Cells / Q000473:pathology; D005260:Female; D006801:Humans; D050356:Lipid Metabolism / Q000187:drug effects; D008297:Male; D008315:Malondialdehyde / Q000097:blood; D008875:Middle Aged; D009043:Motor Activity; D009765:Obesity / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D018384:Oxidative Stress / Q000187:drug effects*; D011236:Prediabetic State / Q000175:diagnosis / Q000378:metabolism / Q000628:therapy; D013223:Statistics as Topic; D016896:Treatment Outcome
chemical_list: D000975:Antioxidants; D015415:Biomarkers; D008315:Malondialdehyde