title: Repackaging of Intravenous Fat Emulsions: A Clinical Conundrum.
abstract: To accommodate small fluid volumes, repackaging of intravenous fat emulsions (IVFEs) is frequently performed in institutions providing parenteral nutrition to neonates and smaller pediatric patients. However, some consider this an unsafe practice. Concerns for potential administration errors leading to an overdose of IVFEs are weighed against the potential for microbial contamination from the repackaging process. The clinician providing pediatric nutrition support should tailor repackaging practices to ensure patient safety and quality. This discussion aims to describe the strengths and limitations surrounding IVFE repackaging to provide guidance regarding the practice.
authors: Department of Pharmacy, Akron Children's Hospital, Akron, Ohio, USA Department of Pharmacy Practice, Northeast Ohio Medical University, Rootstown, Ohio, USA mcober@chmca.org.
authors: M Petrea
authors: MP
authors: Cober
mesh_terms: D004349:Drug Packaging / Q000379:methods*; D005217:Fat Emulsions, Intravenous / Q000008:administration & dosage*; D006801:Humans; D007223:Infant; D007231:Infant, Newborn; D008508:Medication Errors / Q000517:prevention & control*; D010288:Parenteral Nutrition / Q000379:methods*
chemical_list: D005217:Fat Emulsions, Intravenous
keywords: intravenous fat emulsions; neonates; parenteral nutrition; parenteral nutrition solutions; pediatrics