title: [Radiotherapy during pregnancy].
abstract: The diagnostic of cancer during pregnancy is a rare and delicate situation. As the developments of the embryo and the human fetus are extremely sensitive to ionizing radiations, the treatment of these tumors should be discussed. The studies - preclinical and clinical - based mostly on exposure accidents show that subdiaphragmatic treatments are possible during pregnancy. When radiotherapy is used, phantom estimations of the dose to the fetus, confirmed by in vivo measurements are required. Irradiation and imaging techniques should be arranged to decrease as much as possible the dose delivered to the fetus and hold below the threshold of 0.1Gy.
authors: Département d'oncologie-radiothérapie, Gustave-Roussy Cancer Campus, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Université Paris-Sud, membre de l'université Paris Saclay, 15, rue Georges-Clemenceau, 91400 Orsay, France. Electronic address: renaud.mazeron@gustaveroussy.fr.
authors: R
authors: R
authors: Mazeron
authors: Département d'oncologie-radiothérapie, centre hospitalier universitaire Bretonneau, 2, boulevard Tonnellé, 37000 Tours, France; Université François-Rabelais, 10, boulevard Tonnellé, 37032 Tours, France.
authors: I
authors: I
authors: Barillot
authors: EMR 3738, université Claude-Bernard Lyon 1, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France; Département de radiothérapie-oncologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France.
authors: F
authors: F
authors: Mornex
authors: Département d'oncologie-radiothérapie, hôpital européen Georges-Pompidou, 20, rue Leblanc, 75015 Paris, France; Université Paris-Descartes, Paris-Cité Sorbonne, 12, rue de l'École-de-Médecine, 75006 Paris, France.
authors: P
authors: P
authors: Giraud
mesh_terms: D000016:Abnormalities, Radiation-Induced / Q000209:etiology / Q000517:prevention & control; D000075202:Contraindications; D005260:Female; D005333:Fetus / Q000528:radiation effects; D005865:Gestational Age; D006801:Humans; D019047:Phantoms, Imaging; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000532:radiotherapy*; D011829:Radiation Dosage; D011835:Radiation Protection / Q000295:instrumentation / Q000379:methods; D011878:Radiotherapy / Q000009:adverse effects / Q000379:methods / Q000592:standards; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D012306:Risk
keywords: Dose measurements; Fetus; Fœtus; Grossesse; Mesures de dose; Pregnancy; Radiation techniques; Radiotherapy; Radiothérapie; Techniques d’irradiation