title: Glucomannan's protective effect on the virulence of Vibrio splendidus in pacific oyster.
abstract: We examine the effect of Glucomannan, extracted from Candida utilis yeast, on immune parameters and resistance to Vibrio splendidus of Crassostreagigas. Our results showed that Glucomannan was a successful anti-adhesive molecule; it exhibited a stronger inhibitory effect on adhesion of Vibrio splendidus in infected Crassostreagigas. Vibrio splendidus viable cells number declined after incubation with Glucomannan. Furthermore, the Glucomannan diet showed higher activity to trigger the immune response against bacteria. Glucomannan applications, in biological control of seafood associated pathogens can be an alternative solution, providing consumer with a product of good quality owing to the use of 40 non-toxic compounds. Based on our results, Glucomannan could be used as a bio-protective culture in oyster's depuration to prevent Vibrio splendidus growth.
authors: Laboratory of Analysis, Treatment and Valorization of Pollutants of the Environment and Products (LATVPEP), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.
authors: Kais
authors: K
authors: Fdhila
authors: Laboratory of Analysis, Treatment and Valorization of Pollutants of the Environment and Products (LATVPEP), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia. Electronic address: najla_haddaji@yahoo.fr.
authors: Najla
authors: N
authors: Haddaji
authors: Laboratory of Analysis, Treatment and Valorization of Pollutants of the Environment and Products (LATVPEP), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.
authors: Ibtissem
authors: I
authors: Chakroun
authors: Laboratory of Analysis, Treatment and Valorization of Pollutants of the Environment and Products (LATVPEP), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.
authors: Mohammed Ezz Eddine
authors: MEE
authors: Macherki
authors: Laboratory of Transmissible Diseases and Biologically Active Substances, Tunisia.
authors: Faten
authors: F
authors: Nefzi
authors: Laboratory of Analysis, Treatment and Valorization of Pollutants of the Environment and Products (LATVPEP), Faculty of Pharmacy, University of Monastir, Monastir 5000, Tunisia.
authors: Amina
authors: A
authors: Bakhrouf
mesh_terms: D000821:Animal Feed / Q000032:analysis; D000818:Animals; D002175:Candida / Q000737:chemistry; D049896:Crassostrea / Q000187:drug effects* / Q000276:immunology*; D004032:Diet; D006434:Hemocytes / Q000187:drug effects / Q000382:microbiology; D007113:Immunity, Innate / Q000187:drug effects*; D008351:Mannans / Q000494:pharmacology; D014733:Vibrio / Q000187:drug effects* / Q000502:physiology
chemical_list: D008351:Mannans; C022901:(1-6)-alpha-glucomannan
keywords: Crassostreagigas; Glucomannan; Vibrio splendidus