title: A Versatile Axle for the Construction of Disassemblage Rotaxanes.
abstract: Rotaxanes are unique mechanical devices that hold great promise as sensors. We report on two new rotaxanes that contain an acid or base sensitive trigger and readily disassemble in a wide range of environments. Disassemblage was observed under TLC and ¹H-NMR analysis. The axle is highly charged, which enhances solubility in aqueous environments, and can be readily derivatized with sensor components. The trigger was swapped in a one-pot method, which is promising for the rapid production of a series of sensors.
authors: Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA. powersla@mail.uc.edu.
authors: Lucas A
authors: LA
authors: Powers
authors: Department of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA. david.smithrud@uc.edu.
authors: David B
authors: DB
authors: Smithrud
mesh_terms: D006863:Hydrogen-Ion Concentration; D009682:Magnetic Resonance Spectroscopy; D043862:Rotaxanes / Q000138:chemical synthesis / Q000737:chemistry*; D012995:Solubility
chemical_list: D043862:Rotaxanes
keywords: disassemble; pH; rotaxanes; switch