title: Intestine-Specific, Oral Delivery of Captopril/Montmorillonite: Formulation and Release Kinetics.
abstract: The intercalation of captopril (CP) into the interlayers of montmorillonite (MMT) affords an intestine-selective drug delivery system that has a captopril-loading capacity of up to ca. 14 %w/w and which exhibits near-zero-order release kinetics.
authors: Industrial Chemistry Laboratory, Central Leather Research Institute, Council of Scientific and Industrial Research, Chennai, 600 020, India.
authors: Suguna Lakshmi
authors: SL
authors: Madurai
authors: Industrial Chemistry Laboratory, Central Leather Research Institute, Council of Scientific and Industrial Research, Chennai, 600 020, India.
authors: Stella Winnarasi
authors: SW
authors: Joseph
authors: Industrial Chemistry Laboratory, Central Leather Research Institute, Council of Scientific and Industrial Research, Chennai, 600 020, India.
authors: Asit Baran
authors: AB
authors: Mandal
authors: Biomaterials & Drug Delivery Research Group, School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, Hampshire, PO1 2DT, UK.
authors: John
authors: J
authors: Tsibouklis
authors: Industrial Chemistry Laboratory, Central Leather Research Institute, Council of Scientific and Industrial Research, Chennai, 600 020, India. induchem2000@yahoo.com.
authors: Boreddy Sr
authors: BS
authors: Reddy
keywords: Captopril montmorillonite; Intercalation; Intestine-specific controlled release; Release kinetics