title: Bilateral hamartomatous medullary lipoma within the nasal turbinate bones in a cynomolgus monkey (Macaca fascicularis).
abstract: A 15-year-old male cynomolgus monkey (Macaca fascicularis) showed large bilateral masses in the maxillary sinus. In histopathological examination, both masses revealed benign medullary lipomas within the turbinate bones. The tumors were composed of well-developed lipocytes, trabecular bones and a few blood vessels. Although we initially diagnosed the tumor as bilateral lipomas in the nasal turbinates, it was not differentiated from lipomatous hamartoma. Findings, such as unique symmetrical proliferation, lack of border from the normal marrow and the intact surrounding tissue, indicated a lipomatous hamartoma/hamartomatous lipoma, thought to be a suitable diagnosis of the lesion. Of most interest was that such a proliferating lesion occurred in the nasal turbinate.
authors: Toxicology and Pharmacokinetics Group, Non-clinical Research, R&D Division, Santen Pharmaceutical Co., Ltd., 8916-16 Takayama-cho, Ikoma-shi, Nara 630-0101, Japan.
authors: Osamu
authors: O
authors: Katsuta
authors: Toru
authors: T
authors: Shibata
authors: Yumi
authors: Y
authors: Kuriki-Yamamoto
authors: Takaharu
authors: T
authors: Mochizuki
authors: Miwa
authors: M
authors: Yoshimi
authors: Takahisa
authors: T
authors: Noto
authors: Hidetoshi
authors: H
authors: Mano
mesh_terms: D000818:Animals; D001859:Bone Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D020295:Brain Stem Neoplasms / Q000175:diagnosis / Q000662:veterinary*; D003937:Diagnosis, Differential; D006222:Hamartoma / Q000175:diagnosis / Q000662:veterinary*; D008067:Lipoma / Q000175:diagnosis*; D008252:Macaca fascicularis; D008297:Male; D008992:Monkey Diseases / Q000175:diagnosis*; D014420:Turbinates / Q000473:pathology*