title: Coexistence of Acute Crescent Glomerulonephritis and IgG4-Related Kidney Disease.
abstract: BACKGROUND
  IgG4-related disease (IgG4-RD) is a fibroinflammatory disorder that may involve almost each organ or system. IgG4-related kidney disease (IgG4-RKD) refers to renal lesions associated with IgG4-RD. The most frequent morphological type of renal lesions is IgG4-related tubulointerstitial nephritis (IgG4-TIN) which is associated with increased IgG4-positive plasma cell infiltration and interstitial fibrosis.
  
  
  METHODS
  Herein, we present a rare case with coexisting IgG4-RKD and acute crescent glomerulonephritis with concomitant severe tubulointerstitial lesions instead of classic IgG4-TIN.
  
  
  CONCLUSIONS
  IgG4-RKD and acute crescent glomerulonephritis can occur in the same patient. This case may give us a clearer viewpoint of the disease.
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Zeyuan
authors: Z
authors: Lu
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Jianyong
authors: J
authors: Yin
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Hongda
authors: H
authors: Bao
authors: Department of Pathology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Qiong
authors: Q
authors: Jiao
authors: Department of Pathology, Fudan University School of Medicine, Shanghai, China.
authors: Huijuan
authors: H
authors: Wu
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Rui
authors: R
authors: Wu
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Qin
authors: Q
authors: Xue
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Niansong
authors: N
authors: Wang
authors: Department of Pathology, Fudan University School of Medicine, Shanghai, China.
authors: Zhigang
authors: Z
authors: Zhang
authors: Department of Nephrology and Rheumatology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
authors: Feng
authors: F
authors: Wang
keywords: Acute crescent glomerulonephritis; IgG4-related disease; IgG4-related kidney disease; IgG4-related tubulointerstitial nephritis