title: Low use of statins for secondary prevention in primary care: a survey in a northern Swedish population.
abstract: Cholesterol-lowering therapy with statins is recommended in established cardiovascular disease (CVD) and should be considered for patients at high cardiovascular risk. We surveyed statin treatment before first-time myocardial infarction in clinical practice compared to current guidelines, in patients with and without known CVD in primary care clinics with general practitioners (GPs) on short-term contracts vs. permanent staff GPs.
  
  
  
  A total of 931 patients (345 women) in northern Sweden were enrolled in the study between November 2009 and December 2014 and stratified by prior CVD, comprising angina pectoris, revascularisation, ischaemic stroke or transitory ischaemic attack, or peripheral artery disease. Primary care clinics were classified by the proportion of GP salaries that were paid to GPs working on short-term contracts: low (0-9 %), medium (10-39 %), or high (≥40 %). We used logistic regression to identify determinants of statin treatment.
  
  
  
  Among patients with prior CVD, only 34.5 % received statin treatment before myocardial infarction. The probability of statin treatment decreased with age (≥70 years OR 0.30; 95 % CI 0.13-0.66) and female gender (OR 0.39; 95 % CI 0.20-0.78) but increased in patients with diabetes (OR 3.52; 95 % CI 1.75-7.08). Among patients with prior CVD, the type of primary care clinic was not predictive of statin treatment. In the entire study cohort, 17.3 % of patients were treated with statins; women < 70 years old were more likely to receive statin treatment than women ≥70 years old (OR 3.24; 95 % CI 1.64-6.38), and men ≥70 years old were twice as likely to be treated with statins than women of the same age (OR 2.22; 95 % CI 1.31-3.76) after adjusting for diabetes and CVD. Overall, patients from clinics with predominantly permanent staff GPs received statin therapy less frequently than those with GPs on short-term contracts.
  
  
  
  In patients with prior CVD we found considerable under-treatment with statins, especially among women and the elderly. Methodologies for case findings, recall, and follow-up need to be improved and implemented to reach the goals for CVD prevention in clinical practice.
authors: Department of Public Health and Clinical Medicine, Unit of Research, Education and Development - Östersund, Umeå University, Umeå, Sweden. gunnar.nilsson@regionjh.se.
authors: Gunnar
authors: G
authors: Nilsson
authors: Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
authors: Eva
authors: E
authors: Samuelsson
authors: Unit of Research, Education and Development, Östersund Hospital, Region Jämtland, Härjedalen, Sweden.
authors: Lars
authors: L
authors: Söderström
authors: Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
authors: Thomas
authors: T
authors: Mooe
mesh_terms: D000367:Age Factors; D000368:Aged; D000369:Aged, 80 and over; D000554:Ambulatory Care Facilities / Q000458:organization & administration*; D002318:Cardiovascular Diseases / Q000188:drug therapy; D004651:Employment / Q000706:statistics & numerical data; D005260:Female; D058005:General Practitioners / Q000706:statistics & numerical data*; D019538:Health Care Surveys; D006801:Humans; D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors / Q000627:therapeutic use*; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000517:prevention & control*; D017410:Practice Guidelines as Topic; D011320:Primary Health Care / Q000458:organization & administration / Q000706:statistics & numerical data*; D055502:Secondary Prevention / Q000706:statistics & numerical data*; D012737:Sex Factors; D013548:Sweden
chemical_list: D019161:Hydroxymethylglutaryl-CoA Reductase Inhibitors
keywords: Cardiovascular disease; Myocardial infarction; Secondary prevention; Statins