title: Potentially inappropriate prescribing in nursing home residents detected with the community pharmacist specific GheOP(3)S-tool.
abstract: Background The Ghent Older People's Prescriptions community Pharmacy Screening (GheOP³S-)tool was recently developed to screen for potentially inappropriate prescribing (PIP). Objective We aimed (1) to determine PIP prevalence in older nursing home (NH) residents with polypharmacy using the GheOP³S-tool and (2) to identify those PIPs that are most frequently detected. Method A cross-sectional study was carried out between February and June 2014 in 10 NHs in Belgium, supplied by a community pharmacy chain. For each NH, 40 residents (≥70 years, using ≥5 chronic drugs) were included. PIP prevalence was determined using the GheOP³S-tool. Results 400 NH residents were included [mean age (±SD) 86.2 (±6.3) years; median number of drugs (±IQR) 10 (7-12)]. A total of 1728 PIPs were detected in 387 (97 %) participants (Median 4; IQR 2-6). The most prevalent items can be assigned to three categories: long-term use of central nervous system drugs (i.e. benzodiazepines, antidepressants and antipsychotics), use of anticholinergic drugs (mutual combinations and with underlying constipation/dementia) and underuse of osteoporosis prophylaxis. Conclusion Screening for PIP by means of the GheOP³S-tool revealed a high prevalence of PIP among older NH residents with polypharmacy. This finding urges for initiatives on the patient-level, but also on a broader, institutional level.
authors: Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemstesteenweg 460, 9000, Ghent, Belgium. Eline.Tommelein@UGent.be.
authors: Eline
authors: E
authors: Tommelein
authors: Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemstesteenweg 460, 9000, Ghent, Belgium.
authors: Els
authors: E
authors: Mehuys
authors: Department of Internal Medicine, Faculty of Medicine and Health Sciences, De Pintelaan 185, 9000, Ghent, Belgium.
authors: Mirko
authors: M
authors: Petrovic
authors: Department of Pharmacy, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.
authors: Annemie
authors: A
authors: Somers
authors: Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemstesteenweg 460, 9000, Ghent, Belgium.
authors: Charlotte
authors: C
authors: Van Damme
authors: Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemstesteenweg 460, 9000, Ghent, Belgium.
authors: Eva
authors: E
authors: Pattyn
authors: Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemstesteenweg 460, 9000, Ghent, Belgium.
authors: Kristof
authors: K
authors: Mattelin
authors: Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemstesteenweg 460, 9000, Ghent, Belgium.
authors: Koen
authors: K
authors: Boussery
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001530:Belgium / Q000453:epidemiology; D003430:Cross-Sectional Studies; D011307:Drug Prescriptions / Q000592:standards; D005260:Female; D006707:Homes for the Aged / Q000592:standards*; D006801:Humans; D057970:Inappropriate Prescribing / Q000517:prevention & control*; D008297:Male; D009735:Nursing Homes / Q000592:standards*; D010594:Pharmacies / Q000592:standards*; D010595:Pharmacists / Q000592:standards*; D011897:Random Allocation
keywords: Aged; Belgium; GheOP³S; Inappropriate prescribing; Nursing homes; PIP