title: Preparation of core-shell magnetic molecular imprinted polymer with binary monomer for the fast and selective extraction of bisphenol A from milk.
abstract: In the current study, a new strategy for the extraction of bisphenol A (BPA) from milk has been employed by using surface-imprinted core-shell magnetic beads, prepared by the reversible addition-fragmentation chain transfer (RAFT) polymerization. In order to obtain highly selective recognition cavities, an enhanced imprinting method based on binary functional monomers, e.g. 4-vinylpyridine (4-VP) and β-cyclodextrin (β-CD), was chosen for BPA imprinting. The morphological and magnetic properties of the Fe3O4-MIP beads were characterized by Transmission Electron Microscopy (TEM), Fourier Transform Infrared (FT-IR) Spectroscopy, Thermogravimetric Analysis (TGA), and Vibrating Sample Magnetometer (VSM). The characterization results suggested that MIP was synthesized evenly on Fe3O4-SiO2 surface. The adsorption experiments revealed that Fe3O4-MIPs showed better extraction capacity and selectivity toward BPA and its analogues than the non-imprinted polymers (NIPs). The saturation capacity of Fe3O4-MIP was 17.98mg/g. In milk samples, the present method displayed a lower the detection thresholds, down to 3.7μg/L. The recoveries of BPA in milk samples for three concentrations were found to be within 99.21%, 98.07% and 97.23%, respectively to three concentrations: 1.0μmol/L, 10.0mol/L, 100.0μmol/L. Thus, the MIPs can be used for remove BPA in milk samples.
authors: Department of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.
authors: Yanhao
authors: Y
authors: Yuan
authors: Department of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.
authors: Yan
authors: Y
authors: Liu
authors: Department of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.
authors: Weidi
authors: W
authors: Teng
authors: Department of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.
authors: Jiean
authors: J
authors: Tan
authors: Department of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China. Electronic address: liangy@scnu.edu.cn.
authors: Yong
authors: Y
authors: Liang
authors: Department of Chemistry and Environment, South China Normal University, Guangzhou, 510006, China.
authors: Youwen
authors: Y
authors: Tang
mesh_terms: D000327:Adsorption; D000818:Animals; D001559:Benzhydryl Compounds / Q000737:chemistry* / Q000302:isolation & purification*; D005290:Ferric Compounds / Q000737:chemistry; D008280:Magnetics; D046529:Microscopy, Electron, Transmission; D008892:Milk / Q000737:chemistry*; D054802:Molecular Imprinting; D010636:Phenols / Q000737:chemistry* / Q000302:isolation & purification*; D058105:Polymerization; D011108:Polymers / Q000737:chemistry*; D011725:Pyridines / Q000737:chemistry; D012822:Silicon Dioxide / Q000737:chemistry; D017550:Spectroscopy, Fourier Transform Infrared; D047392:beta-Cyclodextrins / Q000737:chemistry; D000098826:Bisphenol A Compounds
chemical_list: D001559:Benzhydryl Compounds; D005290:Ferric Compounds; D010636:Phenols; D011108:Polymers; D011725:Pyridines; D012822:Silicon Dioxide; D047392:beta-Cyclodextrins; C029351:4-vinylpyridine; C006780:bisphenol A; D000098826:Bisphenol A Compounds
keywords: Atom transfer radical polymerization; Binary monomer; Bisphenol A; Molecularly imprinted polymers (MIPs); β-cyclodextrin