title: Spinal metastases: multimodality imaging in diagnosis and stereotactic body radiation therapy planning.
abstract: Due to increased effectiveness of cancer treatments and increasing survival rates, metastatic disease has become more frequent compared to the past, with the spine being the most common site of bony metastases. Diagnostic imaging is an integral part of screening, diagnosis and follow-up of spinal metastases. In this article, we review the principles of multimodality imaging for tumor detection with respect to their value for diagnosis and stereotactic body radiation therapy planning for spinal metastases. We will also review the current international consensus agreement for stereotactic body radiation therapy planning, and the role of imaging in achieving the best possible treatment plan.
authors: Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
authors: Pejman
authors: P
authors: Jabehdar Maralani
authors: Department of Radiation Oncology, University of Washington School of Medicine, Seattle, WA, USA.
authors: Simon S
authors: SS
authors: Lo
authors: Department of Radiation Oncology, Johns Hopkins Medical Institutions, Baltimore, MD, USA.
authors: Kristin
authors: K
authors: Redmond
authors: Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
authors: Hany
authors: H
authors: Soliman
authors: Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
authors: Sten
authors: S
authors: Myrehaug
authors: Department of Therapeutic Radiology, Yale University School of Medicine, New Haven, CT, USA.
authors: Zain A
authors: ZA
authors: Husain
authors: Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
authors: Chinthaka
authors: C
authors: Heyn
authors: Department of Medical Imaging, University of Toronto, Toronto, ON, Canada.
authors: Anish
authors: A
authors: Kapadia
authors: Sunnybrook Research Institute, University of Toronto, Toronto, ON, Canada.
authors: Aimee
authors: A
authors: Chan
authors: Department of Radiation Oncology, University of Toronto, Toronto, ON, Canada.
authors: Arjun
authors: A
authors: Sahgal
mesh_terms: D006801:Humans; D064847:Multimodal Imaging / Q000379:methods; D016634:Radiosurgery / Q000379:methods; D011880:Radiotherapy Planning, Computer-Assisted; D013125:Spinal Neoplasms / Q000000981:diagnostic imaging* / Q000532:radiotherapy* / Q000556:secondary*; D016896:Treatment Outcome
keywords: CT scan; MRI; PET; SBRT; SPECT; bone scan; metastasis; scintigraphy; spine