title: The Determination of Protonation Constants of Peptidomimetic Cyclophanes in Binary Methanol-Water Mixtures.
abstract: The protonation constants of new group of peptidomimetic cyclophanes with valine or phenylalanine moieties incorporated into the macrocyclic skeleton as well as their linear analogues were determined by potentiometric measurements in solutions of methanol-water mixtures at 25°C and constant ionic strength. The influence of cavity size, location of protonation sites, and attached substituents of the macrocyclic ligands on the protonation constants were discussed on the basis of potentiometric measurement as well as H(1)-NMR results.
authors: Department of Inorganic and Analytical Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland.
authors: Piotr
authors: 0000-0002-8850-1074
authors: P
authors: Seliger
authors: Department of Inorganic and Analytical Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland.
authors: Danuta
authors: D
authors: Tomczyk
authors: Department of Inorganic and Analytical Chemistry, University of Lodz, Tamka 12, 91-403 Lodz, Poland.
authors: Grzegorz
authors: G
authors: Andrijewski
authors: Department of Biochemistry and Genetics, Institute of Biology, Jan Kochanowski University in Kielce, Swietokrzyska 15 A, 25-406 Kielce, Poland.
authors: Ewa
authors: 0000-0001-7914-1022
authors: E
authors: Tomal