title: Ferromagnetic particles as magnetic resonance imaging temperature sensors.
abstract: Magnetic resonance imaging is an important technique for identifying different types of tissues in a body or spatial information about composite materials. Because temperature is a fundamental parameter reflecting the biological status of the body and individual tissues, it would be helpful to have temperature maps superimposed on spatial maps. Here we show that small ferromagnetic particles with a strong temperature-dependent magnetization, can be used to produce temperature-dependent images in magnetic resonance imaging with an accuracy of about 1 °C. This technique, when further developed, could be used to identify inflammation or tumours, or to obtain spatial maps of temperature in various medical interventional procedures such as hyperthermia and thermal ablation. This method could also be used to determine temperature profiles inside nonmetallic composite materials.
authors: UCCS Center for the BioFrontiers Institute, University of Colorado, Colorado Springs, Colorado 80918, USA.
authors: J H
authors: JH
authors: Hankiewicz
authors: UCCS Center for the BioFrontiers Institute, University of Colorado, Colorado Springs, Colorado 80918, USA.
authors: Z
authors: Z
authors: Celinski
authors: National Institute of Standards and Technology, Boulder, Colorado 80305, USA.
authors: K F
authors: KF
authors: Stupic
authors: UCCS Center for the BioFrontiers Institute, University of Colorado, Colorado Springs, Colorado 80918, USA.
authors: N R
authors: NR
authors: Anderson
authors: UCCS Center for the BioFrontiers Institute, University of Colorado, Colorado Springs, Colorado 80918, USA.
authors: R E
authors: RE
authors: Camley