title: Benign Cutaneous Disease Among Polish Renal Transplant Recipients.
abstract: BACKGROUND
  Organ transplant recipients are an at-risk group for skin cancers and benign cutaneous diseases. Immunosuppression type, dosage, and treatment length dictates the frequency of benign lesions.
  
  
  METHODS
  Two hundred twenty-three consecutive adult renal transplant recipients (RTRs) were enrolled and screened for benign skin lesions. During examination, swabs, skin scrapings, and nail clippings were collected from any suspected areas infection and any cutaneous lesions marked for quality and quantity on a special questionnaire. The aim was to examine the prevalence of benign cutaneous disease and risk factors.
  
  
  RESULTS
  Fungal infections were the most common infections found (60%), most commonly in the oral cavity (40.8%). Viral warts occurred in 18.4%, being significantly more common in those transplanted over 5 years (P = .002). Hypertrichosis was the most common pilosebaceous disorder found (P ≤ .001). Other iatrogenic cutaneous effects included purpura (50.2%), xerosis (41.2%), and gingival hyperplasia (28.2%), the latter strongly associated with cyclosporine (P = .0005). Seborrhoeic warts (23.8%) were most common in patients older than 50 years (P < .001). One-third of subjects had skin tags (31%).
  
  
  CONCLUSIONS
  This is the largest study of the prevalence and type of non-malignant cutaneous diseases in Polish RTRs. We see increasing numbers of patients with long-term side effects from immunosuppressive therapy, and treatment, gender, age, and time since transplantation should be considered with new skin lesions in everyday practice with RTRs.
  
  
  CONCLUSIONS
  The study group had a high prevalence of benign cutaneous diseases and these should not be overlooked as they can cause aesthetic problems and reduced quality of life.
authors: Dermatology and Venereology Clinic, Copernicus- Independent Public Healthcare Centre, Gdansk, Poland.
authors: B
authors: B
authors: Imko-Walczuk
authors: Department of Dermatology, Copernicus- Independent Public Healthcare Centre, Gdansk, Poland; Chair & Department of Medical Chemistry, Medical University of Gdansk, Gdansk, Poland. Electronic address: a.okuniewska@gumed.edu.pl.
authors: A
authors: A
authors: Okuniewska
authors: Dermatology and Venereology Clinic, Copernicus- Independent Public Healthcare Centre, Gdansk, Poland.
authors: A
authors: A
authors: Prędota-Głowacka
authors: Clinical Department of Oncological Surgery, Medical University of Gdansk, Gdansk, Poland.
authors: J
authors: J
authors: Jaśkiewicz
authors: Department of Dermatology, Sexually Transmitted Diseases and Immunodermatogy, University of Nicolaus Copernicus Torun, Bydgoszcz, Poland.
authors: W
authors: W
authors: Placek
authors: Department of Transplantation and General Surgery, University Hospital, University of Nicolaus Copernicus Torun, Bydgoszcz, Poland.
authors: Z
authors: Z
authors: Włodarczyk
authors: Department of Nephrology, Transplantology and Internal Disease, Medical University of Gdansk, Gdansk, Poland.
authors: A
authors: A
authors: Dębska-Ślizień
authors: Department of Nephrology, Transplantology and Internal Disease, Medical University of Gdansk, Gdansk, Poland.
authors: B
authors: B
authors: Rutkowski
mesh_terms: D000328:Adult; D000368:Aged; D005260:Female; D006801:Humans; D007165:Immunosuppression Therapy / Q000009:adverse effects*; D016030:Kidney Transplantation / Q000009:adverse effects*; D008297:Male; D008875:Middle Aged; D011044:Poland / Q000453:epidemiology; D011183:Postoperative Complications / Q000453:epidemiology* / Q000209:etiology; D015995:Prevalence; D012307:Risk Factors; D012871:Skin Diseases / Q000453:epidemiology* / Q000209:etiology; D012878:Skin Neoplasms / Q000453:epidemiology / Q000209:etiology; D055815:Young Adult