title: In situ microemulsion synthesis of hydroxyapatite-MgFe2O4 nanocomposite as a magnetic drug delivery system.
abstract: In this study, an innovative synthesis process has been developed to produce hydroxyapatite-magnesium ferrite (HA-MgFe2O4) nanocomposite. In addition, the effect of calcination temperature on drug delivery behavior of produced samples was investigated. HA-MgFe2O4 nanocomposite was prepared via one-step modified reverse microemulsion synthesis route. The resulting products were characterized by X-ray Diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), vibrating sample magnetometer (VSM), and Brunauer-Emmett-Teller surface area analysis (BET). The calcined samples at 500 and 700°C demonstrated mesoporous characteristics and large specific surface areas of 88 and 32m(2)/g, respectively. TEM and VSM results showed that the nanocomposite calcined at 700°C has core-shell morphology and a maximum saturation magnetization of 9.47emug(-1).
authors: Young Researchers and Elite Club, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
authors: Firoozeh
authors: F
authors: Foroughi
authors: Young Researchers and Elite Club, Najafabad Branch, Islamic Azad University, Najafabad, Iran. Electronic address: tabrizi1980@gmail.com.
authors: S A
authors: SA
authors: Hassanzadeh-Tabrizi
authors: Advanced Materials Research Center, Department of Materials Engineering, Najafabad Branch, Islamic Azad University, Najafabad, Iran.
authors: Ashkan
authors: A
authors: Bigham
mesh_terms: D016503:Drug Delivery Systems / Q000379:methods*; D017886:Durapatite / Q000737:chemistry*; D004655:Emulsions; D052203:Ferrosoferric Oxide / Q000737:chemistry*; D007052:Ibuprofen / Q000737:chemistry*; D008274:Magnesium / Q000737:chemistry*; D060526:Magnetic Fields; D053761:Nanocomposites / Q000737:chemistry*
chemical_list: D004655:Emulsions; D017886:Durapatite; D008274:Magnesium; D007052:Ibuprofen; D052203:Ferrosoferric Oxide
keywords: Drug delivery; Hydroxyapatite; Ibuprofen; Magnesium ferrite; Microemulsion synthesis