title: Pleomorphic rhabdomyosarcoma of the left atrium mimicking myxoma.
abstract: Primary rhabdomyosarcoma (RMS) of the heart is a rare malignant tumor which has poor prognosis and survival despite surgery and adjuvant chemotherapy. The preoperative diagnosis is often difficult in view of nonspecific clinicoradiological findings. This report describes a case of a 60-year-old woman who was clinically diagnosed as left atrial myxoma. A diagnosis of pleomorphic RMS was made on histopathology after excision. Our case discusses the clinicopathological features and treatment options of cardiac RMS emphasizing the fact that histopathology and immunohistochemistry are essential to confirm the diagnosis of such an aggressive malignant tumor.
authors: Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors: Tanvi
authors: T
authors: Aggarwal
authors: Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors: Surbhi
authors: S
authors: Goyal
authors: Department of Pathology, Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
authors: Sufian
authors: S
authors: Zaheer
mesh_terms: D000199:Actins / Q000032:analysis; D014408:Biomarkers, Tumor / Q000032:analysis; D003893:Desmin / Q000032:analysis; D003937:Diagnosis, Differential; D005260:Female; D006325:Heart Atria / Q000473:pathology*; D006338:Heart Neoplasms / Q000175:diagnosis* / Q000000981:diagnostic imaging / Q000473:pathology* / Q000601:surgery; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008853:Microscopy; D008875:Middle Aged; D009232:Myxoma / Q000175:diagnosis* / Q000473:pathology*; D013902:Radiography, Thoracic; D012208:Rhabdomyosarcoma / Q000175:diagnosis* / Q000473:pathology* / Q000601:surgery; D014057:Tomography, X-Ray Computed
chemical_list: D000199:Actins; D014408:Biomarkers, Tumor; D003893:Desmin