title: Quality of life in relapsing-remitting multiple sclerosis patients receiving CinnoVex compared with Avonex.
abstract: OBJECTIVE
  There is an increasing recognition among clinicians and researchers that the impact of chronic illnesses and their treatments must be assessed in terms of their quality of life (QoL) in addition to more traditional measures of clinical outcomes. The aim of this study was to compare the QoL in patients with relapsing-remitting multiple sclerosis (RRMS) using Avonex or CinnoVex.
  
  
  METHODS
  We conducted a cross-sectional study on one hundred patients with RRMS, fifty and fifty patients were being treated with Avonex (Biogen Idec, USA) and CinnoVex (CinnaGen, Iran), respectively. We used a disease-specific questionnaire for MS (Multiple Sclerosis Quality of Life-54 [MSQoL-54]). Both groups were tested for significant differences regarding sociodemographic. A multiple linear regression model was constructed to find factors that affected the different aspect of QoL of the whole sample of patients.
  
  
  RESULTS
  MS groups did not differ in physical and mental health composite scores as well as relative scales. The results of regression models for each subscale showed that age, marriage, and Expanded Disability Status Scale were associated with several subscales of the MSQoL-54 (P < 0.05).
  
  
  CONCLUSIONS
  In this study, it was seen that there are no significant differences between QoL of Avonex and CinnoVex, but a limitation in our study the results may be different in other countries and even various areas in Iran.
authors: Department of Health Service Administration, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Nahid
authors: N
authors: Hatam
authors: Health Human Resources Research Center, Department of Health Service Management, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Peivand
authors: P
authors: Bastani
authors: Department of Health Economics, Shiraz University of Medical Sciences, Shiraz, Iran.
authors: Rahil Sadat
authors: RS
authors: Shahtaheri
keywords: Interferon beta-1 alpha; multiple sclerosis; quality of life