title: Pulmonary hemangioendothelioma with osteoclast-like giant cells: A rare observation.
abstract: Pulmonary epithelioid hemangioendothelioma (PEH) is a rare vascular neoplasm, predominantly encountered in women, more often in the age group of 40 years and below. It is a tumor of borderline malignant potential with a clinical course intermediate between hemangioma and angiosarcoma. The tumor has variable prognosis, and treatment options include surgical excision in operable cases and chemotherapy in disseminated ones. The present report describes complete clinical, radiological, and histopathological features of PEH with osteoclast-like giant cells and metaplastic ossification in a 20-year-old boy who presented with dyspnea and episodes of hemoptysis with review of literature.
authors: Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
authors: Shraddha A
authors: SA
authors: Adamane
authors: Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
authors: Kedar K
authors: KK
authors: Deodhar
authors: Department of Surgical Oncology (Thoracic), Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
authors: Amit M
authors: AM
authors: Gupta
authors: Department of Surgical Oncology (Thoracic), Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
authors: George
authors: G
authors: Karimundackal
authors: Department of Pathology, Tata Memorial Hospital, Parel, Mumbai, Maharashtra, India.
authors: Sangeeta B
authors: SB
authors: Desai
mesh_terms: D014408:Biomarkers, Tumor / Q000032:analysis; D004417:Dyspnea / Q000175:diagnosis / Q000209:etiology; D015726:Giant Cells / Q000166:cytology*; D006390:Hemangioendothelioma / Q000175:diagnosis* / Q000473:pathology*; D006469:Hemoptysis / Q000175:diagnosis / Q000209:etiology; D006651:Histocytochemistry; D006801:Humans; D007150:Immunohistochemistry; D008175:Lung Neoplasms / Q000175:diagnosis* / Q000473:pathology*; D008297:Male; D008840:Microfilament Proteins / Q000032:analysis; D008853:Microscopy; D009999:Ossification, Heterotopic; D010010:Osteoclasts / Q000166:cytology*; D019408:Platelet Endothelial Cell Adhesion Molecule-1 / Q000032:analysis; D018160:Receptors, Cytoplasmic and Nuclear / Q000032:analysis; D015534:Trans-Activators; D055815:Young Adult
chemical_list: D014408:Biomarkers, Tumor; C098179:FLII protein, human; D008840:Microfilament Proteins; D019408:Platelet Endothelial Cell Adhesion Molecule-1; D018160:Receptors, Cytoplasmic and Nuclear; D015534:Trans-Activators