title: Oncocytic Intraductal Papillary Mucinous Neoplasms of the Pancreas: Imaging and Histopathological Findings.
abstract: To evaluate and correlate computed tomography/magnetic resonance findings and histopathologic features of oncocytic intraductal papillary mucinous neoplasms (O-IPMNs).
  
  
  
  Computed tomography/magnetic resonance examinations and resection specimens of 16 O-IPMNs were retrospectively reviewed. Qualitative and quantitative imaging features were analyzed according to "worrisome features" and "high risk stigmata." Correlations between radiological and histopathological findings were evaluated using Fisher test.
  
  
  
  Most O-IPMNs (75%) presented as large mixed- or main duct-type lesions (mean size, 56.9 mm; range, 20-180); all branch-duct type lesions were larger than 3 cm. Ten lesions presented main pancreatic duct dilation of 10 mm or greater. Solid enhancing nodules were found in 10 cases. Two lesions presented foci of invasion at histopathologic analysis, the remaining presented high-grade dysplasia. Neither invasive carcinoma nor nodal metastases were found. No significant correlations were found between radiological predictors of malignancy and histopathological features.
  
  
  
  Oncocytic tumors are rare subtypes of pancreatic IPMN, whose imaging features are similar to other IPMN subtypes. Imaging predictors of malignancy as large size and huge solid internal nodules are frequently encountered in O-IPMNs; despite this, these features are not correlated with histopathological findings, being probably inapplicable to O-IPMNs.
authors: From the *Department of Radiology, G.B. Rossi Hospital, University of Verona, Verona; †Department of Radiology, Casa di cura Pederzoli, Peschiera del Garda; ‡Department of Pathology, G.B. Rossi Hospital, University of Verona, Verona; §Department of Pathology, Casa di cura Pederzoli, Peschiera del Garda; ∥Department of Radiology, Ca' Foncello Hospital, Treviso; ¶Department of Surgery, G.B. Rossi Hospital, University of Verona, Verona; and #Department of Surgery, Casa di cura Pederzoli, Peschiera del Garda, Italy.
authors: Mirko
authors: M
authors: D'Onofrio
authors: Riccardo
authors: R
authors: De Robertis
authors: Paolo
authors: P
authors: Tinazzi Martini
authors: Paola
authors: P
authors: Capelli
authors: Stefano
authors: S
authors: Gobbo
authors: Giovanni
authors: G
authors: Morana
authors: Emanuele
authors: E
authors: Demozzi
authors: Giovanni
authors: G
authors: Marchegiani
authors: Roberto
authors: R
authors: Girelli
authors: Roberto
authors: R
authors: Salvia
authors: Claudio
authors: C
authors: Bassi
authors: Paolo
authors: P
authors: Pederzoli
mesh_terms: D002288:Adenocarcinoma, Mucinous; D021441:Carcinoma, Pancreatic Ductal; D006801:Humans; D010183:Pancreatic Ducts; D010190:Pancreatic Neoplasms