title: When Mr. Fap Meets the Gals.
abstract: Fusobacteria are found to be overrepresented in the colorectal tumor microenvironment. In this issue of Cell Host & Microbe, Abed et al. (2016) describe a novel homing mechanism by which fusobacteria localize to tumors by recognizing a host polysaccharide (Gal-GalNAc) on cancer cells using a fusobacterial lectin, Fap2.
authors: Biological Sciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: skg12@case.edu.
authors: Santosh K
authors: SK
authors: Ghosh
authors: Biological Sciences, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, OH 44106, USA. Electronic address: axw47@case.edu.
authors: Aaron
authors: A
authors: Weinberg
mesh_terms: D015179:Colorectal Neoplasms / Q000382:microbiology*; D045182:Fusobacteria; D006801:Humans; D037102:Lectins; D011134:Polysaccharides
chemical_list: D037102:Lectins; D011134:Polysaccharides