title: Standardization of Fractional Flow Reserve Measurements.
abstract: Pressure wire-based fractional flow reserve is considered the standard of reference for evaluation of the ischemic potential of coronary stenoses and the expected benefit from revascularization. Accordingly, its application in daily practice or for research purposes has to be as standardized as possible to avoid technical or operator-related artifacts in pressure recordings. This document proposes a standardized way of acquiring, recording, interpreting, and archiving the pressure tracings for daily practice and for the purpose of clinical research involving a core laboratory. Proposed standardized steps enhance the uniformity of clinical practices and data interpretation.
authors: University Heart Centre Graz, Graz, Austria.
authors: Gabor G
authors: GG
authors: Toth
authors: Weatherhead PET Center for Preventing and Reversing Atherosclerosis, Division of Cardiology, Department of Medicine, University of Texas Medical School and Memorial Hermann Hospital, Houston, Texas.
authors: Nils P
authors: NP
authors: Johnson
authors: Stony Brook University and Cardiovascular Research Foundation, New York, New York.
authors: Allen
authors: A
authors: Jeremias
authors: Cardiovascular Center Aalst, Aalst, Belgium.
authors: Mariano
authors: M
authors: Pellicano
authors: Hartcentrum Hasselt, Division of Cardiology and Critical Care Medicine, Hasselt, Belgium.
authors: Pascal
authors: P
authors: Vranckx
authors: Division of Cardiovascular Medicine, Stanford University Medical Center, Stanford, California.
authors: William F
authors: WF
authors: Fearon
authors: Cardiovascular Center Aalst, Aalst, Belgium; Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
authors: Emanuele
authors: E
authors: Barbato
authors: Irvine Medical Center, University of California, Irvine, California.
authors: Morton J
authors: MJ
authors: Kern
authors: Irvine Medical Center, University of California, Irvine, California; Department of Cardiology, Catharina Hospital, Eindhoven, the Netherlands; Department of Biomedical Engineering, Eindhoven University of Technology, Eindhoven, the Netherlands.
authors: Nico H J
authors: NH
authors: Pijls
authors: Cardiovascular Center Aalst, Aalst, Belgium. Electronic address: bernard.de.bruyne@olvz-aalst.be.
authors: Bernard
authors: B
authors: De Bruyne
mesh_terms: D001783:Blood Flow Velocity / Q000502:physiology; D003324:Coronary Artery Disease / Q000175:diagnosis* / Q000503:physiopathology / Q000601:surgery; D003331:Coronary Vessels / Q000502:physiology*; D053805:Fractional Flow Reserve, Myocardial / Q000502:physiology*; D006801:Humans; D062645:Percutaneous Coronary Intervention; D012015:Reference Standards
keywords: coronary artery disease; functional assessment; percutaneous coronary intervention