title: Inducing and Evaluating Skeletal Muscle Injury by Notexin and Barium Chloride.
abstract: Models of skeletal muscle injury in animal models are invaluable tools to assess muscle stem cell (MuSC)-mediated tissue repair. The optimization and comprehensive evaluation of these approaches have greatly improved our ability to assess MuSC regenerative potential. Here we describe the procedures for skeletal muscle injury with notexin and BaCl2 and assessment of the dynamics of tissue regeneration.
authors: Graduate School of Biomedical Sciences, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.|Development, Aging and Regeneration Program, Sanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA.
authors: Matthew T
authors: MT
authors: Tierney
authors: Development, Aging and Regeneration Program, Sanford Children's Health Research Center, Sanford Burnham Prebys Medical Discovery Institute, 10901 North Torrey Pines Road, La Jolla, CA, 92037, USA. asacco@sbpdiscovery.org.
authors: Alessandra
authors: A
authors: Sacco
mesh_terms: D000818:Animals; D017609:Barium Compounds / Q000009:adverse effects*; D002712:Chlorides / Q000009:adverse effects*; D004195:Disease Models, Animal; D004546:Elapid Venoms / Q000009:adverse effects*; D007150:Immunohistochemistry / Q000379:methods; D051379:Mice; D018482:Muscle, Skeletal / Q000187:drug effects* / Q000473:pathology*; D009135:Muscular Diseases / Q000139:chemically induced* / Q000473:pathology*; D012038:Regeneration
chemical_list: D017609:Barium Compounds; D002712:Chlorides; D004546:Elapid Venoms; C024986:barium chloride; C005082:notexin
keywords: Muscle regeneration; Skeletal muscle injury