title: Two case reports of generalized pustular psoriasis of pregnancy: Different outcomes.
abstract: Generalized pustular psoriasis of pregnancy is a rare dermatosis with potential serious consequences for both the mother and fetus. Treatment is difficult and historically steroids were the mainstay of treatment. Cyclosporin has been used for a few cases resistant to steroids. We report our own experience of two cases of generalized pustular psoriasis of pregnancy. Cases of generalized pustular psoriasis of pregnancy need review by a dermatologist with experience of skin disorders in pregnancy. Both the fetus and mother need to be monitored closely when systemic illness occurs, as there is a risk of stillbirth. Maternal sepsis is a known complication of generalized pustular psoriasis of pregnancy. Cyclosporin, when used appropriately is effective and relatively safe.
authors: Department of Dermatology, St. James's Hospital Dublin, Dublin, Ireland.
authors: Aoibheann
authors: A
authors: Flynn
authors: Department of Gynaecology, St. James's Hospital Dublin, Dublin, Ireland.
authors: Naomi
authors: N
authors: Burke
authors: Department of Obstetrics and Gynaecology, The Coombe Women and Infants Maternity Hospital, Dublin, Ireland.
authors: Bridgette
authors: B
authors: Byrne
authors: Department of Gynaecology, St. James's Hospital Dublin, Dublin, Ireland.
authors: Noreen
authors: N
authors: Gleeson
authors: Department of Dermatology, St. James's Hospital Dublin, Dublin, Ireland.
authors: Bairbre
authors: B
authors: Wynne
authors: Department of Dermatology, St. James's Hospital Dublin, Dublin, Ireland.
authors: Louise
authors: L
authors: Barnes
keywords: Generalized pustular psoriasis; cyclosporin; pregnancy; sepsis