title: Validation and comparison of instruments to identify frail patientes in primary care settings: Study protocol.
abstract: In the last few years several indices and tools, aimed at identifying frail subjects in various care settings have been developed. However, to date none of them has been incorporated into usual practice in the primary care setting. The purposes of this study are: 1) to evaluate the predictive capacity of the Tilburg Frailty Indicator (TFI), the Gérontopôle Frailty Screening Tool (GFST) and the KoS model together with two biomarker levels (SOX2 and p16INK4a) for adverse events related to frailty; 2) to determine differences in the use of healthcare services according to frailty.
  
  
  
  Prospective multicentre cohort study with a 2-year follow-up. The study will be performed in primary care centres of Gipuzkoa and Costa del Sol, both located in Spain. Autonomous, non-institutionalized individuals aged 70 and over that agree to participate in this study will constitute the study population. A total of 900 individuals will be randomly selected from the healthcare administrative data bases of the participating health services. Data will be collected at baseline and at 1 and 2 years. The main independent variables assessed at baseline will be TFI outcomes, GFST and the KoS model, together with the expression of SOX2 and p16INK4a levels. During follow-up, loss of autonomy, the occurrence of death and consumption of healthcare resources will be assessed.
  
  
  
  The main focus of this work is the identification and evaluation of several instruments constructed under different rationales to identify frail subjects in primary care settings. The resulting outcomes have potential for direct application to the primary care practice. Early identification of the onset of functional impairment of elderly is an essential, still unresolved aspect in the prevention of dependence in the scope of primary care.
authors: Unidad de Investigación APOSIs Gipuzkoa, Osakidetza, Donostia-San Sebastian, Spain. ivergara@osakidetza.eus.|Instituto Biodonostia, Donostia-San Sebastian, ᅟSpain. ivergara@osakidetza.eus.|Red de Investigación en Servicios de Salud en Enfermedades Crónicas, REDISSEC, Paseo Dr. Begiristain s/n; 2014, San Sebastián-Donostia, Spain. ivergara@osakidetza.eus.
authors: Itziar
authors: I
authors: Vergara
authors: Red de Investigación en Servicios de Salud en Enfermedades Crónicas, REDISSEC, Paseo Dr. Begiristain s/n; 2014, San Sebastián-Donostia, Spain.|Agencia Sanitaria Costa del Sol, Marbella, Málaga, Spain.
authors: Francisco
authors: F
authors: Rivas-Ruiz
authors: Unidad de Investigación APOSIs Gipuzkoa, Osakidetza, Donostia-San Sebastian, Spain.|Instituto Biodonostia, Donostia-San Sebastian, ᅟSpain.|Red de Investigación en Servicios de Salud en Enfermedades Crónicas, REDISSEC, Paseo Dr. Begiristain s/n; 2014, San Sebastián-Donostia, Spain.
authors: Kalliopi
authors: K
authors: Vrotsou
authors: Distrito de Atención Primaria Costa del Sol, Mijas, Málaga, Spain.
authors: Eugenio
authors: E
authors: Contreras-Fernández
authors: Red de Investigación en Servicios de Salud en Enfermedades Crónicas, REDISSEC, Paseo Dr. Begiristain s/n; 2014, San Sebastián-Donostia, Spain.|Agencia Sanitaria Costa del Sol, Marbella, Málaga, Spain.
authors: Teresa
authors: T
authors: Téllez-Santana
authors: Unidad de Investigación APOSIs Gipuzkoa, Osakidetza, Donostia-San Sebastian, Spain.|Instituto Biodonostia, Donostia-San Sebastian, ᅟSpain.|Red de Investigación en Servicios de Salud en Enfermedades Crónicas, REDISSEC, Paseo Dr. Begiristain s/n; 2014, San Sebastián-Donostia, Spain.
authors: Mónica
authors: M
authors: Machón
authors: Instituto Biodonostia, Donostia-San Sebastian, ᅟSpain.|Centro de Salud Beraun, OSI Donostialdea, Osakidetza, Renteria, Spainᅟ
authors: Ana Isabel
authors: AI
authors: Díez Ruiz
authors: Unidad de Gestión Clínica de La Lobilla, Estepona, Málaga, Spain.|Unidad Gestión Clínica Los Boliches, Fuengirola, Málaga, Spain.
authors: Yolanda
authors: Y
authors: de Mesa Berenguer
authors: Centro de Salud Beraun, OSI Donostialdea, Osakidetza, Renteria, Spainᅟ
authors: Andoni
authors: A
authors: Bueno
authors: Centro de Salud Beraun, OSI Donostialdea, Osakidetza, Renteria, Spainᅟ
authors: Jazmina
authors: J
authors: Núñez
authors: Unidad Gestión Clínica Los Boliches, Fuengirola, Málaga, Spain.|Unidad de Gestión Clínica San Miguel, Torremolinos, Málaga, Spain.
authors: M Carmen
authors: MC
authors: Saucedo Figueredo
authors: Unidad de Gestión Clínica San Miguel, Torremolinos, Málaga, Spain.
authors: Alonso
authors: A
authors: Montiel-Luque
authors: Unidad de Gestión Clínica San Miguel, Torremolinos, Málaga, Spain.
authors: M Antonia
authors: MA
authors: Nava Del Val
authors: Red de Investigación en Servicios de Salud en Enfermedades Crónicas, REDISSEC, Paseo Dr. Begiristain s/n; 2014, San Sebastián-Donostia, Spain.|Agencia Sanitaria Costa del Sol, Marbella, Málaga, Spain.
authors: Raúl
authors: R
authors: Quirós-López
authors: Neuro-Oncology Group, Biodonostia Institute, Paseo Dr. Beguiristain s/n, San Sebastian, Spain.
authors: Estefanía
authors: E
authors: Carrasco
authors: Gérontopôle, Centre Hospitalier Universitaire de Toulouse, Toulouse, France.|INSERM UMR1027, Université de Toulouse III Paul Sabatier, Toulouse, France.
authors: Gabor
authors: G
authors: Abellan
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D016330:Frail Elderly; D015577:Geriatric Assessment / Q000379:methods*; D006296:Health Services; D006801:Humans; D008297:Male; D011320:Primary Health Care; D011446:Prospective Studies; D013030:Spain; D011795:Surveys and Questionnaires
keywords: Frailty; Identification tools; Primary care