title: [Hepatic tumors and radiotherapy].
abstract: Recent technological developments led to develop the concept of focused liver radiation therapy. We must distinguish primary and secondary tumors as the indications are restricted and must be discussed as an alternative to surgical or medical treatments. For hepatocellular carcinoma 5 to 10cm (or more), a conformational radiation with or without intensity modulation is performed. Stereotactic body radiotherapy (SBRT) is being evaluated and is increasingly proposed as an alternative to radiofrequency ablative treatment for primary or secondary tumors (typically less than 5cm). Tumor (and liver) movements induced by respiratory motions must be taken into account. Strict dosimetric criteria must be met with particular attention to the dose-volume histograms to liver and the hollow organs, including cases of SBRT.
authors: Service de radiothérapie, institut de cancérologie de l'Ouest, boulevard Jacques-Monod, 44805 Saint-Herblain, France. Electronic address: emmanuel.rio@ico.unicancer.fr.
authors: E
authors: E
authors: Rio
authors: Département de radiothérapie-oncologie, centre hospitalier Lyon Sud, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France; EMR 3738, université Claude-Bernard Lyon 1, 165, chemin du Grand-Revoyet, 69310 Pierre-Bénite, France.
authors: F
authors: F
authors: Mornex
authors: Service de radiothérapie, institut de cancérologie de Lorraine Alexis-Vautrin, 6, avenue de Bourgogne, 54511 Vandœuvre-lès-Nancy, France.
authors: D
authors: D
authors: Peiffert
authors: Service de radiothérapie, institut de cancérologie de Lorraine Alexis-Vautrin, 6, avenue de Bourgogne, 54511 Vandœuvre-lès-Nancy, France.
authors: A
authors: A
authors: Huertas
mesh_terms: D006528:Carcinoma, Hepatocellular / Q000532:radiotherapy*; D003131:Combined Modality Therapy; D019583:Dose Fractionation, Radiation; D006801:Humans; D008113:Liver Neoplasms / Q000532:radiotherapy* / Q000556:secondary; D058958:Organs at Risk; D010166:Palliative Care / Q000379:methods; D011832:Radiation Injuries / Q000517:prevention & control; D016634:Radiosurgery / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D011879:Radiotherapy Dosage; D011880:Radiotherapy Planning, Computer-Assisted; D020266:Radiotherapy, Conformal / Q000009:adverse effects / Q000379:methods* / Q000592:standards; D061089:Radiotherapy, Image-Guided / Q000379:methods
keywords: Carcinome hépatocellulaire; Conformational radiotherapy; Foie; Hepatocellular carcinoma; Liver; Liver metastasis; Métastases hépatiques; Radiothérapie conformationnelle; Radiothérapie en conditions stéréotaxiques; Stereotactic radiotherapy