title: Periodontal conditions and incidence of new cardiovascular events among patients with coronary vascular disease.
abstract: We wanted to investigate whether periodontal conditions and/or oral care habits are associated with new cardiovascular events among patients with coronary vascular disease (CVD).
  
  
  
  In this longitudinal cohort study, 1002 inpatients with CVD were included. They were examined regarding prevalence of severe periodontitis, bleeding upon probing (BOP), number of missing teeth and oral care habits. The combined endpoint was defined as myocardial infarction, stroke/transient ischaemic attack, cardiovascular death and death caused by stroke. Survival analyses were carried out after a 3-year follow-up period. Hazard ratios (HRs) were adjusted for known cardiac risk factors using Cox regression.
  
  
  
  Nine hundred and fifty-three patients completed the 3-year follow-up. The overall incidence of the combined endpoint was 16.4%. Significant HRs for BOP (HR = 2, 95% CI: 1.2-3.3), severe tooth loss (HR = 1.8, 95% CI: 1.3-2.5), brushing teeth more than once a day (HR = 0.6, 95% CI: 0.5-1.0) and use of floss/inter-dental brushes (HR = 0.5, 95% CI: 0.3-0.9) were evaluated only in univariate but not in multivariate survival analyses. Patients with severe periodontitis achieved the combined endpoint more often (18.9% versus 14.2%), but the result was not statistically significant after both univariate and multivariate survival analyses.
  
  
  
  Periodontal conditions and oral care habits are not independent indicators for further adverse events in patients with CVD.
authors: Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany. stefan.reichert@uk-halle.de.
authors: Stefan
authors: S
authors: Reichert
authors: Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Susanne
authors: S
authors: Schulz
authors: Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Ann-Christin
authors: AC
authors: Benten
authors: Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.|Department of Internal Medicine III, Heart Centre of the University Clinics Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Andrea
authors: A
authors: Lutze
authors: Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.|Department of Internal Medicine III, Heart Centre of the University Clinics Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Tim
authors: T
authors: Seifert
authors: Department of Internal Medicine III, Heart Centre of the University Clinics Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Manuela
authors: M
authors: Schlitt
authors: Department of Internal Medicine III, Heart Centre of the University Clinics Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Karl
authors: K
authors: Werdan
authors: Department of Cardiothoracic Surgery, Heart Centre of the University Clinics Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Britt
authors: B
authors: Hofmann
authors: Institute for Medical Epidemiology, Biostatistics, and Informatics, Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Andreas
authors: A
authors: Wienke
authors: Department of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.
authors: Hans-Günter
authors: HG
authors: Schaller
authors: Department of Internal Medicine III, Heart Centre of the University Clinics Halle (Saale), Martin Luther University Halle-Wittenberg, Halle, Germany.|Department of Cardiology, Paracelsus Harz-Clinic Bad Suderode, Halle, Germany.
authors: Axel
authors: A
authors: Schlitt
mesh_terms: D015331:Cohort Studies; D003324:Coronary Artery Disease; D006801:Humans; D015994:Incidence; D010510:Periodontal Diseases
keywords: coronary vascular disease; new cardiovascular events; periodontal conditions; risk factors