title: Hormone replacement therapy benefits meibomian gland dysfunction in perimenopausal women.
abstract: Meibomian gland dysfunction (MGD) is believed to be the leading cause of dry eye (DE) disease worldwide. The connection between aging and MGD has long been recognized. However, few studies have addressed the relationship between MGD and hormone replacement therapy (HRT) in perimenopausal women, and not have examined the prevalence of MGD in perimenopausal women. The purpose of this study was to address and evaluate the possible relationship between MGD and HRT in perimenopausal women.The results suggest that perimenopausal women have a high prevalence of DE related to perimenopausal symptoms. The study also shows that perimenopausal women who use HRT can gain benefits for DE as well as for perimenopausal symptoms. Physicians caring for women who are experiencing DE related to perimenopausal symptoms should consider HRT.
authors: Eye Center, Second Affiliated Hospital, School of Medicine, Zhejiang University Department of Obstetrics and Gynecology, Hangzhou Maternity Hospital, Hangzhou, China.
authors: Xiuming
authors: X
authors: Jin
authors: Zhenyun
authors: Z
authors: Lin
authors: Yufang
authors: Y
authors: Liu
authors: Lin
authors: L
authors: Lin
authors: Binbin
authors: B
authors: Zhu
mesh_terms: D000328:Adult; D000704:Analysis of Variance; D015331:Cohort Studies; D015352:Dry Eye Syndromes / Q000188:drug therapy* / Q000453:epidemiology / Q000209:etiology; D005141:Eyelid Diseases / Q000150:complications* / Q000175:diagnosis; D005260:Female; D005500:Follow-Up Studies; D020249:Hormone Replacement Therapy / Q000379:methods*; D006801:Humans; D008537:Meibomian Glands / Q000187:drug effects* / Q000503:physiopathology; D017060:Patient Satisfaction; D047648:Perimenopause / Q000502:physiology; D012016:Reference Values; D012189:Retrospective Studies; D018570:Risk Assessment; D016896:Treatment Outcome