title: Lymphoblastic leukemia with surface light chain restriction: A diagnostic dilemma.
abstract: Surface light chain expression is a feature of mature B-cell neoplasms. Light chain restriction in precursor B acute lymphoblastic leukemia is infrequently seen. We report a case of a 28-year-old female with non-FAB L3 morphology blasts and immunophenotypic features showing overlap between a precursor and mature B-cell neoplasm.
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Nikhil
authors: N
authors: Rabade
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Asma
authors: A
authors: Bibi
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Kiran
authors: K
authors: Ghodke
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Nikhil
authors: N
authors: Patkar
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Prashant
authors: P
authors: Tembhare
authors: Department of Cancer Cytogenetics, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Pratibha
authors: P
authors: Amare
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: P G
authors: PG
authors: Subramanian
authors: Department of Pathology, Hematopathology Laboratory, Tata Memorial Hospital, Mumbai, Maharashtra, India.
authors: Sumeet
authors: S
authors: Gujral
mesh_terms: D000328:Adult; D005260:Female; D006801:Humans; D007147:Immunoglobulin Light Chains / Q000096:biosynthesis*; D016130:Immunophenotyping; D015452:Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / Q000175:diagnosis* / Q000473:pathology*; D054448:Precursor Cells, B-Lymphoid / Q000737:chemistry*; D011947:Receptors, Antigen, B-Cell / Q000096:biosynthesis*
chemical_list: D007147:Immunoglobulin Light Chains; D011947:Receptors, Antigen, B-Cell