title: Deteriorating Infrastructure in the Aged Muscle Stem Cell Niche.
abstract: Following an injury, the extracellular matrix (ECM) undergoes dramatic remodeling to facilitate tissue repair. In a new study, Lukjanenko and colleagues show how an age-associated change in this process affects the regenerative ability of muscle stem cells (MuSCs).
authors: Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC, Department of Stem Cell Biology and Regenerative Medicine, Keck School of Medicine of USC, Los Angeles, CA 90033, USA. Electronic address: jtrodger@usc.edu.
authors: Joseph T
authors: JT
authors: Rodgers
mesh_terms: D005109:Extracellular Matrix / Q000737:chemistry*; D009132:Muscles; D032446:Myoblasts; D012038:Regeneration; D055153:Stem Cell Niche