title: Effects of Intradialytic Resistance Exercise on Protein Energy Wasting, Physical Performance and Physical Activity in Ambulatory Patients on Dialysis: A Single-Center Preliminary Study in a Japanese Dialysis Facility.
abstract: Patients under hemodialysis present protein-energy wasting (PEW), which is related with higher mortality rates. The study aimed to determine whether intradialytic resistance exercise training could improve physical performance, physical activity, and PEW in hemodialysis patients. In single center study, 75 hemodialysis patients were enrolled in an intradialytic resistance exercise training consisting of 20 min of adapted leg press, with a gymnastic ball, 3 days/week, during 9 months on the same day of hemodialysis therapy. Physical performance by short physical performance battery (SPPB), physical activity by life space assessment (LSA), and PEW score based on the nomenclature proposed by the International Society of Renal Nutrition and Metabolism in 2008 were assessed at baseline and after 9 months. Intradialytic resistance exercise training significantly improved SPPB score, LSA score, and PEW score (all, P < 0.05). In addition, intradialytic resistance exercise training improved SPPB score in patients with moderate and severe PEW subgroups (P < 0.05), associated with reduced prevalence of the patients with moderate to severe PEW (53% vs. 36%, P < 0.05). Intradialytic resistance exercise training was safe and effective to improve physical performance, physical activity, and PEW in hemodialysis patients.
authors: Department of Physiotherapy, Sakakibara Heart Institute, Tokyo, Japan.|Meiseikai Toyo clinic Yachimata, Chiba, Japan.
authors: Masakazu
authors: M
authors: Saitoh
authors: Meiseikai Toyo clinic Yachimata, Chiba, Japan.
authors: Masumi
authors: M
authors: Ogawa
authors: Innovative Clinical Trials, Department of Cardiology and Pneumology, University Medical Centre Göttingen, Göttingen, Germany.|Heart Institute (InCor), University of Sao Paulo Medical School, Sao Paulo, Brazil.
authors: Marcelo Rodrigues
authors: MR
authors: Dos Santos
authors: Meiseikai Toyo clinic Yachimata, Chiba, Japan.
authors: Hisae
authors: H
authors: Kondo
authors: Meiseikai Toyo clinic Yachimata, Chiba, Japan.
authors: Kiichi
authors: K
authors: Suga
authors: Department of Cardiology, Sakakibara Heart Institute, Tokyo, Japan.
authors: Haruki
authors: H
authors: Itoh
authors: Meiseikai Toyo Clinic, Chiba, Japan.
authors: Yoichiro
authors: Y
authors: Tabata
mesh_terms: D015444:Exercise; D005260:Female; D006801:Humans; D007564:Japan; D008297:Male; D008875:Middle Aged; D009043:Motor Activity; D011502:Protein-Energy Malnutrition / Q000628:therapy*; D011597:Psychomotor Performance; D006435:Renal Dialysis; D055070:Resistance Training / Q000379:methods*
keywords: Hemodialysis; Intradialytic resistance exercise; Physical activity; Physical performance; Protein energy wasting