title: Comparison of morbidity after reconstruction of tongue defects with an anterolateral thigh cutaneous flap compared with a radial forearm free-flap: a meta-analysis.
abstract: Currently the radial forearm fasciocutaneous flap and the anterolateral thigh flap are among the most popular free flaps used for reconstruction of oral soft tissue. However, there is controversy about their efficacy after reconstruction of tongue defects because of their respective intrinsic properties, so we have compared them in reconstruction of tongue defects using meta-analysis. We conducted a search in Pubmed, EMBASE, OVID, Science Direct, the Cochrane Library, and Chinese National Knowledge Infrastructure, which covered all papers published before January 2015. Twelve clinical papers, that included 366 patients with 198 radial forearm flaps and 168 anterolateral flaps, met the criteria. Relevant data were extracted and analysed using systematic meta-analyses. The results showed that the incidence of localised numbness at the donor site of the radial forearm flap postoperatively was significantly higher and satisfaction with the appearance of the donor site significantly lower than in the anterolateral thigh group. There were no differences in flap survival, incidence of vascular crises in the flap, complications, satisfaction with the appearance of the tongue, or the postoperative clarity of speech and swallowing ability. Results suggested that the anterolateral thigh flap is the ideal soft tissue flap for reconstructing defects in the tongue, as there was minimal numbness at the donor site and patients were much more satisfied. Further research is needed to address details of the site and the extent of surgical defects as well as the relations between dissection of the radial flap and repair of the skin graft.
authors: Guangxi Medical University College of Stomatology, No.22 Shuang-Yong Road, Qing-Xue District, Nanning, Guangxi 530021, China. Electronic address: bh_chenhong@126.com.
authors: H
authors: H
authors: Chen
authors: Guangxi Medical University College of Stomatology, No.22 Shuang-Yong Road, Qing-Xue District, Nanning, Guangxi 530021, China. Electronic address: nzhou.gxmu@gmail.com.
authors: N
authors: N
authors: Zhou
authors: Guangxi Medical University College of Stomatology, No.22 Shuang-Yong Road, Qing-Xue District, Nanning, Guangxi 530021, China. Electronic address: wanyingchun218@hotmail.com.
authors: X
authors: X
authors: Huang
authors: Guangxi Medical University College of Stomatology, No.22 Shuang-Yong Road, Qing-Xue District, Nanning, Guangxi 530021, China. Electronic address: chenliyo99@gmail.com.
authors: S
authors: S
authors: Song
mesh_terms: D005542:Forearm; D006801:Humans; D019651:Plastic Surgery Procedures; D016038:Skin Transplantation; D013848:Thigh; D014059:Tongue / Q000601:surgery*; D014060:Tongue Diseases / Q000601:surgery
keywords: Anterolateral thigh flap; Meta-analysis; Radial forearm flap; Tongue cancer; Tongue reconstructive complications