title: Kidney Macrophages: Unique Position Solves a Complex Problem.
abstract: Immune complex-mediated diseases, such as systemic lupus erythematosus, commonly affect the kidney and determine disease prognosis. Stamatiades et al. now propose a kidney-specific mechanism for trans-endothelial transport of small immune complexes that activate strategically positioned tissue resident macrophages.
authors: University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK.
authors: Miriam
authors: M
authors: Berry
authors: University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, CB2 0QH, UK. Electronic address: mrc38@medschl.cam.ac.uk.
authors: Menna R
authors: MR
authors: Clatworthy
mesh_terms: D000936:Antigen-Antibody Complex; D006801:Humans; D007668:Kidney / Q000276:immunology*; D008180:Lupus Erythematosus, Systemic / Q000276:immunology*; D008264:Macrophages / Q000276:immunology
chemical_list: D000936:Antigen-Antibody Complex