title: Evolution from Classical to Non-classical Aggregation-Based Crystal Growth of Calcite by Organic Additive Control.
abstract: Aggregation-based crystal growth is distinct from the classical understanding of solution crystallization. In this study, we reveal that N-stearoyl-l-glutamic acid (C18-Glu, an amphiphile that mimics a biomineralization-relevant biomolecule) can switch calcite crystallization from a classical ion-by-ion growth to a non-classical particle-by-particle pathway, which combines the classical and non-classical crystallization in one system. This growth mechanism change is controlled by the concentration ratio of [C18-Glu]/[Ca(2+)] in solution. The high [C18-Glu]/[Ca(2+)] can stabilize precursor nanoparticles to provide building blocks for aggregation-based crystallization, in which the interaction between C18-Glu and the nanoprecursor phase rather than that of C18-Glu on calcite steps is highlighted. Our finding emphasizes the enrollment of organic additives on metastable nano building blocks, which provides an alternative understanding about organic control in inorganic crystallization.
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Genxing
authors: G
authors: Zhu
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Shasha
authors: S
authors: Yao
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Halei
authors: H
authors: Zhai
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Zhaoming
authors: Z
authors: Liu
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Yaling
authors: Y
authors: Li
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Haihua
authors: H
authors: Pan
authors: Center for Biomaterials and Biopathways and Department of Chemistry and §Qiushi Academy for Advanced Studies, Zhejiang University , Hangzhou, Zhejiang 310027, People's Republic of China.
authors: Ruikang
authors: R
authors: Tang