title: Surgery for Colorectal Cancer - Trends, Developments, and Future Perspectives.
abstract: BACKGROUND
  Although colorectal surgery is long established as the mainstay treatment for colon cancer, certain topics regarding technical fine-tuning to increase postsurgical recurrence-free survival have remained a matter of debate throughout the past years. These include complete mesocolic excision (CME), treatment strategies for metastatic disease, significance of hyperthermic intraperitoneal chemotherapy (HIPEC), and surgical techniques for the treatment of colorectal cancer recurrence. In addition, new surgical techniques have been introduced in oncologic colorectal surgery, and their potential to provide sufficiently radical resection has yet to be proven.
  
  
  METHODS
  A structured review of the literature was performed to identify the current state of the art with regard to the mentioned key issues in colorectal surgery.
  
  
  RESULTS
  This article provides a comprehensive review of the current literature addressing the above-mentioned current challenges in colorectal surgery. The focus lies on the impact of CME and, in relation to this, on lymph node dissection, as well as on treatment of metastatic disease including peritoneal spread, and finally on the treatment of recurrent disease.
  
  
  CONCLUSIONS
  Uniformly, the current literature reveals that surgery aiming at complete malignancy elimination within multimodal treatment approaches represents the fundamental quantum leap for the achievement of long-term tumor-free survival.
authors: Department of General, Visceral, Transplantation Surgery, University of Munich, Campus Großhadern, Munich, Germany.
authors: Markus
authors: M
authors: Rentsch
authors: Department of General, Visceral, Transplantation Surgery, University of Munich, Campus Großhadern, Munich, Germany.
authors: Tobias
authors: T
authors: Schiergens
authors: Department of General, Visceral, Transplantation Surgery, University of Munich, Campus Großhadern, Munich, Germany.
authors: Andrej
authors: A
authors: Khandoga
authors: Department of General, Visceral, Transplantation Surgery, University of Munich, Campus Großhadern, Munich, Germany.
authors: Jens
authors: J
authors: Werner
keywords: Advanced cancer stage; Colorectal cancer; Complete mesocolic resection; Hyperthermic intraperitoneal chemotherapy, HIPEC; Resection; Surgical treatment