title: Crizotinib treatment for refractory pediatric acute myeloid leukemia with RAN-binding protein 2-anaplastic lymphoma kinase fusion gene.
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: A
authors: A
authors: Hayashi
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: R
authors: R
authors: Tanoshima
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: S-I
authors: SI
authors: Tsujimoto
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: M
authors: M
authors: Yanagimachi
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: M
authors: M
authors: Takeuchi
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: K
authors: K
authors: Sasaki
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: J
authors: J
authors: Ikeda
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: R
authors: R
authors: Kajiwara
authors: Department of Pediatrics, Yokohama City University, Yokohama, Japan.
authors: S
authors: S
authors: Ito
authors: Department of Pediatrics, Toho University School of Medicine, Tokyo, Japan.
authors: H
authors: H
authors: Takahashi
mesh_terms: D000077548:Anaplastic Lymphoma Kinase; D002675:Child, Preschool; D003131:Combined Modality Therapy; D000077547:Crizotinib; D019008:Drug Resistance, Neoplasm / Q000187:drug effects / Q000235:genetics; D005260:Female; D018380:Hematopoietic Stem Cell Transplantation; D006801:Humans; D015470:Leukemia, Myeloid, Acute / Q000188:drug therapy / Q000235:genetics* / Q000473:pathology / Q000628:therapy*; D015514:Oncogene Proteins, Fusion / Q000235:genetics*; D047428:Protein Kinase Inhibitors / Q000627:therapeutic use; D011720:Pyrazoles / Q000627:therapeutic use*; D011725:Pyridines / Q000627:therapeutic use*; D020794:Receptor Protein-Tyrosine Kinases / Q000037:antagonists & inhibitors / Q000235:genetics; D012074:Remission Induction; D014184:Transplantation, Homologous
chemical_list: D015514:Oncogene Proteins, Fusion; D047428:Protein Kinase Inhibitors; D011720:Pyrazoles; D011725:Pyridines; C000591371:RANBP2-ALK fusion protein, human; D000077547:Crizotinib; C000626173:ALK protein, human; D000077548:Anaplastic Lymphoma Kinase; D020794:Receptor Protein-Tyrosine Kinases