title: Antifungal and phytotoxic activity of essential oil from root of Senecio amplexicaulis Kunth. (Asteraceae) growing wild in high altitude-Himalayan region.
abstract: This work was aimed to evaluate the essential oil from root of medicinally important plant Senecio amplexicaulis for chemical composition, antifungal and phytotoxic activity. The chemical composition analysed by GC/GC-MS showed the presence of monoterpene hydrocarbons in high percentage with marker compounds as α-phellandrene (48.57%), o-cymene (16.80%) and β-ocimene (7.61%). The essential oil exhibited significant antifungal activity against five phytopathogenic fungi, Sclerotium rolfsii, Macrophomina phaseolina, Rhizoctonia solani, Pythium debaryanum and Fusarium oxysporum. The oil demonstrated remarkable phytotoxic activity in tested concentration and significant reduction in seed germination percentage of Phalaris minor and Triticum aestivum at higher concentrations. The roots essential oil showed high yield for one of its marker compound (α-phellandrene) which makes it important natural source of this compound.
authors: a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
authors: Rajendra
authors: R
authors: Singh
authors: a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
authors: Vivek
authors: V
authors: Ahluwalia
authors: a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
authors: Pratap
authors: P
authors: Singh
authors: a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
authors: Naresh
authors: N
authors: Kumar
authors: a Department of Chemistry , HNB Garhwal University (A Central University) , Srinagar , India.
authors: Om
authors: O
authors: Prakash Sati
authors: b Department of Pharmaceutical Sciences , HNB Garhwal University (A Central University) , Srinagar , India.
authors: Nitin
authors: N
authors: Sati
mesh_terms: D000080462:Acyclic Monoterpenes; D000475:Alkenes / Q000032:analysis; D000531:Altitude; D000935:Antifungal Agents / Q000737:chemistry / Q000494:pharmacology*; D001203:Ascomycota / Q000187:drug effects / Q000472:pathogenicity; D000081005:Cyclohexane Monoterpenes; D005670:Fusarium / Q000187:drug effects / Q000472:pathogenicity; D008401:Gas Chromatography-Mass Spectrometry; D018525:Germination / Q000187:drug effects; D007194:India; D039821:Monoterpenes / Q000032:analysis; D009822:Oils, Volatile / Q000737:chemistry* / Q000494:pharmacology*; D031783:Phalaris / Q000187:drug effects / Q000254:growth & development; D018517:Plant Roots / Q000737:chemistry; D012232:Rhizoctonia / Q000187:drug effects / Q000472:pathogenicity; D012639:Seeds / Q000187:drug effects / Q000254:growth & development; D012674:Senecio / Q000737:chemistry*; D014908:Triticum / Q000187:drug effects / Q000254:growth & development
chemical_list: D000080462:Acyclic Monoterpenes; D000475:Alkenes; D000935:Antifungal Agents; D000081005:Cyclohexane Monoterpenes; D039821:Monoterpenes; D009822:Oils, Volatile; C443996:beta-ocimene; C005403:alpha phellandrene
keywords: Senecio; antifungal activity; essential oil; phytotoxic activity; α-phellandrene