title: Extracorporeal Support for Chronic Obstructive Pulmonary Disease: A Bright Future.
abstract: In the past the only option for the treatment of respiratory failure due to acute exacerbation of chronic obstructive pulmonary disease (aeCOPD) was invasive mechanical ventilation. In recent decades, the potential for extracorporeal carbon dioxide (CO2) removal has been realized. We review the various types of extracorporeal CO2removal, outline the optimal use of these therapies for aeCOPD, and make suggestions for future controlled trials. We also describe the advantages and requirements for an ideal long-term ambulatory CO2removal system for palliation of COPD.
authors: 1 Department of Surgery, Extracorporeal Life Support Laboratory, University of Michigan Medical School, Ann Arbor, MI, USA.|2 Department of Surgery, Section of General Surgery, Columbia University Medical Center, New York, NY, USA.
authors: John M
authors: JM
authors: Trahanas
authors: 1 Department of Surgery, Extracorporeal Life Support Laboratory, University of Michigan Medical School, Ann Arbor, MI, USA.|3 Department of Surgery, Section of Thoracic Surgery, University of Michigan Medical School, Ann Arbor, MI, USA.
authors: William R
authors: WR
authors: Lynch
authors: 1 Department of Surgery, Extracorporeal Life Support Laboratory, University of Michigan Medical School, Ann Arbor, MI, USA.
authors: Robert H
authors: RH
authors: Bartlett
mesh_terms: D002245:Carbon Dioxide / Q000097:blood*; D018450:Disease Progression; D005112:Extracorporeal Circulation / Q000379:methods / Q000639:trends*; D015199:Extracorporeal Membrane Oxygenation; D005544:Forecasting; D006801:Humans; D029424:Pulmonary Disease, Chronic Obstructive / Q000150:complications*; D012131:Respiratory Insufficiency / Q000097:blood / Q000209:etiology / Q000628:therapy*
chemical_list: D002245:Carbon Dioxide
keywords: CO2 removal; COPD; ECCO2R; extracorporeal