title: Serological prevalence of human parvovirus B19 in diseases or disordersrelated to different human body systems.
abstract: OBJECTIVE
  Human parvovirus B19 is a pathogen that affects different parts of the body. We planned this study because of the lack of data on B19 seroprevalence based on different body-system diseases.
  
  
  METHODS
  The prevalence of parvovirus B19 antibodies was investigated retrospectively in 1239 patients by review of medical records from 2009-2012, according to their diseases classified under general titles in compliance with the International Classification of Diseases (ICD-10). Parvovirus B19-specific antibodies were detected by quantitative enzyme immunoassays.
  
  
  RESULTS
  The positivity rate was 27.8% for only IgG, 8.5% for only IgM, and 2.6% for both IgG and IgM. The highest positivity for IgG alone was found in musculoskeletal system and connective tissue diseases (55.9%), while the highest positivity for IgM was found in neoplasms (16.4%). The highest positivity for IgG was seen in rheumatoid arthritis (72.2%) and pregnancy (52.6%), and the highest positivity for total IgM was found in upper respiratory tract disease (21.0%) and hepatic failure (17.1%).
  
  
  CONCLUSIONS
  Parvovirus B19 seroprevalence was relatively low in northeastern Anatolia compared to most serological studies conducted in other regions. We think that this study has provided the first wide-ranging information on the seroprevalence of B19 in diseases and disorders of the major human body systems.
authors: Department of Medical Microbiology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
authors: Osman
authors: O
authors: Aktaş
authors: Department of Virology, Faculty of Veterinary Medicine, Atatürk University, Erzurum, Turkey.
authors: Hakan
authors: H
authors: Aydin
authors: Department of Medical Microbiology, Faculty of Medicine, Atatürk University, Erzurum, Turkey.
authors: Hakan
authors: H
authors: Uslu
mesh_terms: D000914:Antibodies, Viral; D004279:DNA, Viral; D005260:Female; D018594:Human Body; D006801:Humans; D007074:Immunoglobulin G; D007075:Immunoglobulin M; D010322:Parvoviridae Infections; D016732:Parvovirus B19, Human; D011247:Pregnancy; D015995:Prevalence; D016036:Seroepidemiologic Studies
chemical_list: D000914:Antibodies, Viral; D004279:DNA, Viral; D007074:Immunoglobulin G; D007075:Immunoglobulin M
keywords: Human parvovirus B19; ICD-10; human body system diseases; quantitative enzyme immunoassays; seroprevalence