title: Comparison between the use of saline and seawater for nasal obstruction in children under 2 years of age with acute upper respiratory infection.
abstract: OBJECTIVE
  The effectiveness of isotonic and hypertonic saline solutions used to open the nasal passage and improve clinical symptoms was compared in children under 2 years of age admitted with the common cold.
  
  
  METHODS
  The study was performed as a randomized, prospective, and double-blind study. The study included 109 children. The children using saline (0.9%) and seawater (2.3%) as nasal drops (the patient group) and the control group (in which nasal drops were not administered) were compared. Seventy-four patients received nasal drops from package A (seawater) in single days and from package B (physiological saline) in double days.
  
  
  RESULTS
  The mean age of the patients was 9.0 ± 3.9 months and the numbers of boys and girls were 65 (59.6%) and 44 (40.4%), respectively. There was no significant difference between Groups A and B in terms of nasal congestion (P > 0.05). However, a significant difference was found between the control group and Groups A and B (P < 0.05).
  
  
  CONCLUSIONS
  Relief was seen in nasal congestion, weakness, sleep quality, and nutrition with the use of both saline and seawater in children with the common cold. Seawater or saline drops may be added to standard treatment protocols.
authors: Department of Pediatrics, Ankara Pediatric and Pediatric Hematology Oncology Training and Research Hospital, Ankara, Turkey.
authors: Tülin
authors: T
authors: Köksal
authors: Department of Pediatrics, Faculty of Medicine, Turgut Özal University, Ankara, Turkey.
authors: Mehmet Nevzat
authors: MN
authors: Çizmeci
authors: Department of Pediatrics, Faculty of Medicine, Turgut Özal University, Ankara, Turkey.
authors: Davut
authors: D
authors: Bozkaya
authors: Department of Pediatrics, Faculty of Medicine, Turgut Özal University, Ankara, Turkey.
authors: Mehmet Kenan
authors: MK
authors: Kanburoğlu
authors: Department of Pediatrics, Ankara Pediatric and Pediatric Hematology Oncology Training and Research Hospital, Ankara, Turkey.
authors: Şanlıay
authors: Ş
authors: Şahin
authors: Department of Pediatrics, Faculty of Medicine, Turgut Özal University, Ankara, Turkey.
authors: Tuğba
authors: T
authors: Taş
authors: Department of Pediatrics, Faculty of Medicine, Turgut Özal University, Ankara, Turkey.
authors: Çiğdem Nükhet
authors: ÇN
authors: Yüksel
authors: Department of Pediatrics, Faculty of Medicine, Turgut Özal University, Ankara, Turkey.
authors: Mustafa Mansur
authors: MM
authors: Tatli
mesh_terms: D000281:Administration, Intranasal; D004311:Double-Blind Method; D005260:Female; D006801:Humans; D007223:Infant; D008297:Male; D015508:Nasal Obstruction; D011446:Prospective Studies; D012141:Respiratory Tract Infections; D012623:Seawater
keywords: Child; common cold; nasal drop; nasal saline; seawater