title: Population-Based Incidence Rates of First-Ever Stroke in Central Vietnam.
abstract: BACKGROUND
  Stroke incidence data with methodologically acceptable design in Southeast Asia countries is limited. This study aimed to determine incidence of age-, sex- and subtype-specific first-ever stroke (FES) in Vietnam.
  
  
  METHODS
  We conducted a hospital-based retrospective study, targeting all stroke cases hospitalized at a solo-provider hospital in our study site of Nha Trang from January 2009 to December 2011 with International Classification of Diseases, 10th revision (ICD-10) codes I60-69. We calculated positive predictive values (PPVs) of each ICD-10-coded stroke by conducting a detailed case review of 190 randomly selected admissions with ICD-10 codes of I60-I69. These PPVs were then used to estimate annual incident stroke cases from the computerized database. National census data in 2009 was used as a denominator.
  
  
  RESULTS
  2,693 eligible admissions were recorded during the study period. The crude annual incidence rate of total FES was 90.2 per 100,000 population (95% CI 81.1-100.2). The age-adjusted incidence of FES was 115.7 (95% CI 95.9-139.1) when adjusted to the WHO world populations. Importantly, age-adjusted intracerebral hemorrhage was as much as one third of total FES: 36.9 (95% CI 26.1-51.0).
  
  
  CONCLUSIONS
  We found a considerable proportion of FES in Vietnam to be attributable to intracerebral hemorrhage, which is as high or exceeding levels seen in high-income countries. A high prevalence of improperly treated hypertension in Vietnam may underlie the high prevalence of intracerebral hemorrhagic stroke in this population.
authors: Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.|Department of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Goto, Nagasaki, Japan.
authors: Hirotomo
authors: H
authors: Yamanashi
authors: Department of Geriatrics, Khanh Hoa Gerenral Hospital, Nha Trang, Khanh Hoa, Vietnam.
authors: Mai Quang
authors: MQ
authors: Ngoc
authors: Department of Geriatrics, Khanh Hoa Gerenral Hospital, Nha Trang, Khanh Hoa, Vietnam.
authors: Tran Van
authors: TV
authors: Huy
authors: Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
authors: Motoi
authors: M
authors: Suzuki
authors: Department of Neurology and Strokology, University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
authors: Akira
authors: A
authors: Tsujino
authors: Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
authors: Michiko
authors: M
authors: Toizumi
authors: Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
authors: Kensuke
authors: K
authors: Takahashi
authors: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors: Vu Dinh
authors: VD
authors: Thiem
authors: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors: Dang Duc
authors: DD
authors: Anh
authors: National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
authors: Nguyen Thi Hien
authors: NT
authors: Anh
authors: Khanh Hoa Health Service, Nha Trang, Khanh Hoa, Vietnam.
authors: Le Huu
authors: le H
authors: Tho
authors: Department of Island and Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Goto, Nagasaki, Japan.|Department of Community Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
authors: Takahiro
authors: T
authors: Maeda
authors: Nagasaki University School of Tropical Medicine and Global Health, Sakamoto, Nagasaki, Japan.|London School of Hygiene and Tropical Medicine, London, United Kingdom.
authors: Sharon E
authors: SE
authors: Cox
authors: Department of Pediatric Infectious Diseases, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Japan.
authors: Lay-Myint
authors: LM
authors: Yoshida
authors: Department of Clinical Medicine, Institute of Tropical Medicine, Nagasaki University Graduate School of Biomedical Sciences, Sakamoto, Nagasaki, Japan.
authors: Koya
authors: K
authors: Ariyoshi
mesh_terms: D000367:Age Factors; D006760:Hospitalization; D006801:Humans; D015994:Incidence; D012189:Retrospective Studies; D012737:Sex Factors; D020521:Stroke / Q000453:epidemiology*; D014744:Vietnam