title: Acinic Cell Carcinoma of the Parotid Gland with Four Morphological Features.
abstract: Acinic cell carcinoma arising in salivary glands is a rare tumor, accounting for 2% to 5% of the primary neoplasms of the parotid gland. When these tumors are well-differentiated, the neoplasia has innocuous aspect, due to the similarity to normal parotid tissue. This makes the diagnosis difficult. Initially the malignancy of this tumor was uncertain; however, recent studies have declared it as malignant. The female / male ratio is 3:2. The nodule usually presents as solitary and well defined shape. Several authors have used different terms to describe histomorphological patterns of these tumors. Four descriptive categories (solid, microcystic, papillary-cystic and follicular) are useful for pathologists. Here we report a case of a 49 yr old man with a left parotid nodule of 5 cm. Parotidectomy was performed at the Hospital Universitario Miguel Servet, in Zaragoza (Spain). The microscopy showed a tumor with acinic semblance, having the four morphologic patterns previously described. The morphological and immunohistochemical study was consistent with the diagnosis of acinic cell carcinoma.
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: David S
authors: DS
authors: Rosero
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: Ramiro
authors: R
authors: Alvarez
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: Paula
authors: P
authors: Gambó
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: María
authors: M
authors: Alastuey
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: Alberto
authors: A
authors: Valero
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: Nerea
authors: N
authors: Torrecilla
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: A Belén
authors: AB
authors: Roche
authors: Hospital Universitario Miguel Servet, Zaragoza, Spain.
authors: Sara
authors: S
authors: Simón
keywords: Acinic cell carcinoma; Morphologic patterns; Salivary gland