title: [Effect of prostate volume on the peripheral nerve block anesthesia in prostate biopsy].
abstract: OBJECTIVE
  To evaluate the anesthetic efficacy of periprostatic nerve block in transrectal ultrasound(TRUS) guided biopsy on different prostate volume.
  
  
  METHODS
  A total of 568 patients received prostate biopsy in Department of Urology, Subei People's Hospital from May 2013 to September 2015 were retrospectively studied. All patients were divided into local anesthesia group and nerve block group according to different way of anesthesia. Then each group was divided into four subgroups(20-40 ml, >40-60 ml, >60-100 ml and >100 ml subgroups) according to different prostate volume range. After being anaesthetized successfully, patients in two groups underwent prostate biopsy, visual analogue scale(VAS) scores, visual numeric scale(VNS)scores and complications were recorded and analyzed. At inter-group and intra-group in local anesthesia group and nerve block group, Mann-Whitney U test of non-parametric analysis and single factor variance analysis were used to compare the VAS scores and the VNS scores respectively, and chi-square test was used to compare the rates of complication.
  
  
  RESULTS
  The VAS scores of four subgroups: local anesthesia group: 1.9±0.9, 2.8±1.5, 3.8±2.3 and 5.3±2.5; nerve block group: 1.5±0.7, 2.0±0.8, 2.9±1.7 and 4.2±2.0. The VNS scores: local anesthesia group: 3.4±0.6, 2.9±0.6, 2.7±0.5 and 1.6±0.7; nerve block group: 3.7±0.5, 3.3±0.4, 3.0±0.8 and 2.0±0.7. The VAS scores and the VNS scores had significant differences (Z=-3.637-98.253, all P<0.05) at inter-group or intra-group level. For the complication rates of operation, hematuria, blood, urinary retention were significant differences (F=1.347-15.402, all P<0.05) at intra-group level. But there were no significant differences at inter-group level(P>0.05).
  
  
  CONCLUSIONS
  Compared with local anesthesia, ultrasound guided prostate peripheral nerve block anesthesia has great analgesic effect and high safety, but for patients with a large prostate volumethe analgesic effect is inefficiency.
authors: Department of Urology, College of Clinical Medicine, Yangzhou University, Subei People's Hospital, Yangzhou 225001, China.
authors: Y
authors: Y
authors: Luan
authors: X F
authors: XF
authors: Ding
authors: X
authors: X
authors: Gu
authors: S M
authors: SM
authors: Lu
authors: H Z
authors: HZ
authors: Tao
authors: X K
authors: XK
authors: Qi
authors: T B
authors: TB
authors: Huang
authors: B D
authors: BD
authors: Liu
mesh_terms: D000704:Analysis of Variance; D000772:Anesthesia, Local / Q000379:methods*; D000779:Anesthetics, Local / Q000008:administration & dosage*; D001707:Biopsy, Needle; D016009:Chi-Square Distribution; D006801:Humans; D061705:Image-Guided Biopsy; D008012:Lidocaine / Q000008:administration & dosage*; D008297:Male; D009407:Nerve Block / Q000379:methods*; D010147:Pain Measurement; D011467:Prostate / Q000000981:diagnostic imaging* / Q000473:pathology*; D012189:Retrospective Studies; D018084:Ultrasonography, Interventional; D064232:Visual Analog Scale
chemical_list: D000779:Anesthetics, Local; D008012:Lidocaine