title: Pregnancy and ketoacidosis: Is pancreatitis a missing link?
abstract: Non-diabetic ketoacidosis is increasingly recognised in pregnancy, particularly during the third trimester, and is usually associated with vomiting. In many cases, the cause of the vomiting is not identified and resolves rapidly, alongside the metabolic abnormalities, following delivery. Here, we report three cases in which pancreatitis was identified as an underlying cause of the gastrointestinal symptoms. To our knowledge, these are the first reports of pancreatitis precipitating non-diabetic ketoacidosis in pregnancy. This case series highlights the importance of searching for a precipitant for non-diabetic ketoacidosis in pregnancy, rather than focusing solely on management of the resulting metabolic abnormalities.
authors: Department of Acute General Medicine, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headington, Oxford, UK.
authors: Charlotte J
authors: CJ
authors: Frise
authors: Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headington, Oxford, UK.
authors: Anna
authors: A
authors: Ashcroft
authors: Department of Obstetrics, Queen Charlotte's and Chelsea Hospital, Imperial College Healthcare NHS Trust, London, UK.
authors: Bryony A
authors: BA
authors: Jones
authors: Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford University Hospitals NHS Foundation Trust, Headington, Oxford, UK.
authors: Lucy
authors: L
authors: Mackillop
keywords: High anion gap; ketoacidosis; metabolic acidosis; pancreatitis