title: Ataxia.
abstract: OBJECTIVE
  This article introduces the background and common etiologies of ataxia and provides a general approach to assessing and managing the patient with ataxia.
  
  
  RESULTS
  Ataxia is a manifestation of a variety of disease processes, and an underlying etiology needs to be investigated. Pure ataxia is rare in acquired ataxia disorders, and associated symptoms and signs almost always exist to suggest an underlying cause. While the spectrum of hereditary degenerative ataxias is expanding, special attention should be addressed to those treatable and reversible etiologies, especially potentially life-threatening causes. This article summarizes the diseases that can present with ataxia, with special attention given to diagnostically useful features. While emerging genetic tests are becoming increasingly available for hereditary ataxia, they cannot replace conventional diagnostic procedures in most patients with ataxia. Special consideration should be focused on clinical features when selecting a cost-effective diagnostic test.
  
  
  CONCLUSIONS
  Clinicians who evaluate patients with ataxia should be familiar with the disease spectrum that can present with ataxia. Following a detailed history and neurologic examination, proper diagnostic tests can be designed to confirm the clinical working diagnosis.
authors: Tetsuo
authors: T
authors: Ashizawa
authors: Guangbin
authors: G
authors: Xia
mesh_terms: D001259:Ataxia / Q000175:diagnosis* / Q000628:therapy*; D006801:Humans