title: Bacterial Stress Responses during Host Infection.
abstract: Pathogenic bacteria must withstand diverse host environments during infection. Environmental signals, such as pH, temperature, nutrient limitation, etc., not only trigger adaptive responses within bacteria to these specific stress conditions but also direct the expression of virulence genes at an appropriate time and place. An appreciation of stress responses and their regulation is therefore essential for an understanding of bacterial pathogenesis. This review considers specific stresses in the host environment and their relevance to pathogenesis, with a particular focus on the enteric pathogen Salmonella.
authors: Department of Microbiology, University of Washington School of Medicine, Seattle, WA 98195-7735, USA; Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195-7735, USA. Electronic address: fcfang@uw.edu.
authors: Ferric C
authors: FC
authors: Fang
authors: Department of Laboratory Medicine, University of Washington School of Medicine, Seattle, WA 98195-7735, USA.
authors: Elaine R
authors: ER
authors: Frawley
authors: Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
authors: Timothy
authors: T
authors: Tapscott
authors: Department of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO 80045, USA.
authors: Andrés
authors: A
authors: Vázquez-Torres
mesh_terms: D000222:Adaptation, Physiological; D015964:Gene Expression Regulation, Bacterial; D054884:Host-Pathogen Interactions; D012475:Salmonella / Q000472:pathogenicity* / Q000502:physiology*; D012480:Salmonella Infections / Q000276:immunology / Q000382:microbiology; D013312:Stress, Physiological; D037521:Virulence Factors / Q000096:biosynthesis
chemical_list: D037521:Virulence Factors