title: Unknown Pseudocholinesterase Deficiency in a Patient Undergoing TIVA with Planned Motor Evoked Potential Monitoring: A Case Report.
abstract: Pseudocholinesterase abnormalities are a genetic cause of aberrant metabolism of the depolarizing muscle relaxant succinylcholine. This article examines a case where succinylcholine was chosen to facilitate intubation due to its ultra short duration and the request of the surgeon to monitor motor evoked potentials. Following succinylcholine administration the neurophysiologist was unable to obtain motor evoked potentials. This case study highlights the intraoperative and postoperative management of an elderly patient with an unknown pseudocholinesterase deficiency.
authors: Candace
authors: C
authors: Binkley
mesh_terms: D000369:Aged, 80 and over; D000771:Anesthesia, Intravenous / Q000451:nursing*; D001049:Apnea / Q000175:diagnosis / Q000451:nursing* / Q000503:physiopathology; D002091:Butyrylcholinesterase / Q000172:deficiency*; D002574:Cervical Vertebrae / Q000601:surgery*; D017586:Diskectomy / Q000451:nursing*; D019054:Evoked Potentials, Motor / Q000187:drug effects*; D006801:Humans; D007442:Intubation, Intratracheal / Q000451:nursing*; D008297:Male; D008661:Metabolism, Inborn Errors / Q000175:diagnosis / Q000451:nursing* / Q000503:physiopathology; D016343:Monitoring, Intraoperative / Q000451:nursing*; D009719:Nurse Anesthetists; D010243:Paralysis / Q000139:chemically induced / Q000175:diagnosis / Q000451:nursing; D011183:Postoperative Complications / Q000139:chemically induced / Q000175:diagnosis / Q000451:nursing; D013123:Spinal Fusion / Q000451:nursing*; D013390:Succinylcholine / Q000009:adverse effects* / Q000493:pharmacokinetics*
chemical_list: D002091:Butyrylcholinesterase; D013390:Succinylcholine