title: Evaluation of serum levels of IL-9 and IL-17 in human Schistosoma mansoni infection and their relationship with periportal fibrosis.
abstract: Serum levels of IL-9 and IL-17 cytokines were evaluated in patients in the acute, chronic phases and clinical forms of human schistosomiasis and in different classifications of periportal fibrosis. No significant differences between the groups of the disease with serum levels of cytokine were found. However, this study discusses the results of some cytokines that have not fully defined roles in the pathology of human schistosomiasis. Furthermore, an examination was made of subjects in the acute phase. This is an important group that is difficult to identify in areas where the disease is endemic. More studies are being undertaken to study the role of IL-9 and IL-17 in human Schistosoma mansoni infection and their relationship with the immunopathogenesis of disease.
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: Ana Virgínia Matos Sá
authors: AV
authors: Barreto
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: Glaucia Alyne Nunes de
authors: GA
authors: Lacerda
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: Anna Lígia de Castro
authors: AL
authors: Figueiredo
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: George Tadeu Nunes
authors: GT
authors: Diniz
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: Elainne Christine Souza
authors: EC
authors: Gomes
authors: Department of Clinical Medicine, Universidade Federal de Pernambuco, Recife, PE, Brazil.
authors: Ana Lúcia Coutinho
authors: AL
authors: Domingues
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: Constança Simões
authors: CS
authors: Barbosa
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil.
authors: Silvia Maria Lucena
authors: SM
authors: Montengro
authors: Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, Brazil. Electronic address: clarice@cpqam.fiocruz.br.
authors: Clarice Neuenschwander Lins de
authors: CN
authors: Morais
mesh_terms: D000208:Acute Disease; D000293:Adolescent; D000328:Adult; D000818:Animals; D001938:Brazil; D002648:Child; D005260:Female; D006801:Humans; D020381:Interleukin-17 / Q000097:blood*; D016906:Interleukin-9 / Q000097:blood*; D008103:Liver Cirrhosis / Q000276:immunology*; D008297:Male; D012550:Schistosoma mansoni / Q000276:immunology*; D012555:Schistosomiasis mansoni / Q000276:immunology*; D055815:Young Adult
chemical_list: D020381:Interleukin-17; D016906:Interleukin-9
keywords: Evaluation; Interleukin-17; Interleukin-9; Schistosomiasis mansoni