title: Early Results of Simultaneous Transaortic Transcatheter Aortic Valve Implantation and Total Arterial Off-Pump Coronary Artery Revascularization in High-Risk Patients.
abstract: BACKGROUND
  Transcatheter aortic valve implantation (TAVI) has become an alternative procedure for treating aortic stenosis (AS) in patients with advanced age and severe comorbidities. Ischemic heart disease (IHD) is present with AS in 40-50% of patients with typical angina. Considering the high operative mortality and morbidity rates in these patients, hybrid TAVI and off-pump CABG (OPCAB) have become realistic treatment options.
  
  
  RESULTS
  Between August 2014 and November 2015, 12 patients were evaluated for simultaneous TAVI and OPCAB. Because of their advanced age and comorbidities these patients were not considered suitable for standard open heart surgery. PCI was also considered unsuitable, because of left anterior descending artery (LAD) proximal lesions and/or high SYNTAX score. TAVI was conducted through a median sternotomy after left internal thoracic artery (LITA) to LAD anastomosis. In 11 cases OPCAB with LITA and composite RA graft was performed using an aorta no-touch technique. Mean age at operation was 81±6.3 years. Average number of distal anastomoses was 2.6. Perivalvular leakage was mild in 3 patients, trivial in 8, and none in 1. There was no conversion to on-pump procedure and no hospital deaths.
  
  
  CONCLUSIONS
  Simultaneous transaortic TAVI and OPCAB in high-risk patients with severe AS and IHD is a reasonable option. This method could be an alternative to surgical aortic valve replacement and CABG. (Circ J 2016; 80: 1946-1950).
authors: Department of Cardiovascular Surgery, National Cerebral and Cardiovascular Center.
authors: Junjiro
authors: J
authors: Kobayashi
authors: Yusuke
authors: Y
authors: Shimahara
authors: Tomoyuki
authors: T
authors: Fujita
authors: Hideaki
authors: H
authors: Kanzaki
authors: Makoto
authors: M
authors: Amaki
authors: Hiroki
authors: H
authors: Hata
authors: Yuta
authors: Y
authors: Kume
authors: Kizuku
authors: K
authors: Yamashita
authors: Atsushi
authors: A
authors: Okada
mesh_terms: D000368:Aged; D000369:Aged, 80 and over; D001024:Aortic Valve Stenosis / Q000150:complications / Q000401:mortality / Q000601:surgery; D005260:Female; D006801:Humans; D008297:Male; D017202:Myocardial Ischemia / Q000150:complications / Q000401:mortality / Q000601:surgery; D009204:Myocardial Revascularization / Q000379:methods*; D012307:Risk Factors; D065467:Transcatheter Aortic Valve Replacement / Q000009:adverse effects / Q000379:methods*