title: Associations between uterine fibroids and obstetric outcomes in twin pregnancies.
abstract: OBJECTIVE
  To examine potential associations between the presence of fibroids and obstetric outcomes in twin pregnancies.
  
  
  METHODS
  A prospective cohort study compared obstetric outcomes between individuals with twin pregnancies who did and did not have fibroids. Patients were considered for inclusion if they underwent first-trimester ultrasonography examination, and went on to deliver at the Beijing Obstetrics and Gynecology Hospital between September 1, 2012 and December 31, 2014. Participants were grouped based on the presence or absence of fibroids and baseline demographics, fibroid characteristics, and obstetric outcomes were recorded and compared between the two groups.
  
  
  RESULTS
  In total, 153 patients with twin pregnancies were recruited; 51 had fibroids and 102 did not. Patients in the fibroid group demonstrated a higher maternal age (P<0.001), higher pre-pregnancy body mass index (P=0.01), and higher rate of assisted reproductive technology use (P=0.04). The presence of fibroids was not associated with any change in obstetric outcomes, and obstetric outcomes were unaffected by the number, size, location, and type of fibroids (all P>0.05).
  
  
  CONCLUSIONS
  Fibroids were not a risk factor for any adverse obstetric outcomes among patients with twin pregnancies.
authors: Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors: Hong-Mei
authors: HM
authors: Wang
authors: Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors: Yu-Cui
authors: YC
authors: Tian
authors: Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors: Zhi-Fang
authors: ZF
authors: Xue
authors: Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China.
authors: Yue
authors: Y
authors: Zhang
authors: Department of Gynecology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing, China. Electronic address: fcyydym@163.com.
authors: Yin-Mei
authors: YM
authors: Dai
mesh_terms: D000328:Adult; D002681:China; D036861:Delivery, Obstetric; D005260:Female; D006801:Humans; D007231:Infant, Newborn; D007889:Leiomyoma / Q000000981:diagnostic imaging / Q000453:epidemiology*; D016015:Logistic Models; D008423:Maternal Age; D015999:Multivariate Analysis; D011247:Pregnancy; D011252:Pregnancy Complications, Neoplastic / Q000453:epidemiology*; D011256:Pregnancy Outcome / Q000453:epidemiology*; D011264:Pregnancy Trimesters; D059285:Pregnancy, Twin; D011446:Prospective Studies; D012307:Risk Factors; D016216:Ultrasonography, Prenatal; D014594:Uterine Neoplasms / Q000000981:diagnostic imaging / Q000453:epidemiology*
keywords: Fibroids; Obstetric outcomes; Twin pregnancies