title: The Effectiveness and Safety of a Homeopathic Medicinal Product in Pediatric Upper Respiratory Tract Infections With Fever: A Randomized Controlled Trial.
abstract: We investigated the clinical effectiveness of a homeopathic add-on therapy in a pediatric subpopulation with upper respiratory tract infections (URTI) in a randomized, controlled, multinational clinical trial. Patients received either on-demand symptomatic standard treatment (ST-group) or the same ST plus a homeopathic medication (Influcid; IFC-group) for 7 days. Outcome assessment was based on symptom and fever resolution and the Wisconsin Upper Respiratory Symptom Survey-21 (WURSS-21). A total of 261 pediatric (<12 years) patients (130 IFC-group; 131 ST-group) were recruited in Germany and the Ukraine. The IFC-group used less symptomatic medication, symptoms resolved significantly earlier (P = .0001), had higher proportions of fever-free children from day 3 onwards, and the WURSS-assessed global disease severity was significantly less (P < .0001) during the entire URTI episode. One adverse event (vomiting) was possibly related to IFC. IFC as add-on treatment in pediatric URTI reduced global disease severity, shortened symptom resolution, and was safe in use.
authors: International Institute for Integrated Medicine, Kingston, UK.
authors: Robert
authors: R
authors: van Haselen
authors: General Practitioner, Private Practice, Munich, Germany.
authors: Manuela
authors: M
authors: Thinesse-Mallwitz
authors: Bogomolets National Medical University, Kiev, Ukraine.
authors: Vitaliy
authors: V
authors: Maidannyk
authors: International Health Center of the Hague, The Hague, The Netherlands.
authors: Stephen L
authors: SL
authors: Buskin
authors: Acomed statistik, Leipzig, Germany.
authors: Stephan
authors: S
authors: Weber
authors: Acomed statistik, Leipzig, Germany.
authors: Thomas
authors: T
authors: Keller
authors: Deutsche Homöopathie-Union, Karlsruhe, Germany.
authors: Julia
authors: J
authors: Burkart
authors: Deutsche Homöopathie-Union, Karlsruhe, Germany.
authors: Petra
authors: P
authors: Klement
keywords: Influcid®; fever; homeopathy; pediatrics; randomized controlled clinical trial; upper respiratory tract infections