title: Acid-sensing ion channels and transient-receptor potential ion channels in zebrafish taste buds.
abstract: Sensory information from the environment is required for life and survival, and it is detected by specialized cells which together make up the sensory system. The fish sensory system includes specialized organs that are able to detect mechanical and chemical stimuli. In particular, taste buds are small organs located on the tongue in terrestrial vertebrates that function in the perception of taste. In fish, taste buds occur on the lips, the flanks, and the caudal (tail) fins of some species and on the barbels of others. In fish taste receptor cells, different classes of ion channels have been detected which, like in mammals, presumably participate in the detection and/or transduction of chemical gustatory signals. However, since some of these ion channels are involved in the detection of additional sensory modalities, it can be hypothesized that taste cells sense stimuli other than those specific for taste. This mini-review summarizes current knowledge on the presence of transient-receptor potential (TRP) and acid-sensing (ASIC) ion channels in the taste buds of teleosts, especially adult zebrafish. Up to now ASIC4, TRPC2, TRPA1, TRPV1 and TRPV4 ion channels have been found in the sensory cells, while ASIC2 was detected in the nerves supplying the taste buds.
authors: Department of Veterinary Sciences, University of Messina, Italy.
authors: M
authors: M
authors: Levanti
authors: Department of Veterinary Sciences, University of Messina, Italy.
authors: B
authors: B
authors: Randazzo
authors: Department of Morphology and Cellular Biology, University of Oviedo, Spain.
authors: E
authors: E
authors: Viña
authors: Department of Veterinary Sciences, University of Messina, Italy. Electronic address: gmontalbano@unime.it.
authors: G
authors: G
authors: Montalbano
authors: Department of Morphology and Cellular Biology, University of Oviedo, Spain.
authors: O
authors: O
authors: Garcia-Suarez
authors: Department of Veterinary Sciences, University of Messina, Italy.
authors: A
authors: A
authors: Germanà
authors: Department of Morphology and Cellular Biology, University of Oviedo, Spain; Faculty of Health Sciences, University of Chile, Chile.
authors: J A
authors: JA
authors: Vega
authors: Department of Veterinary Sciences, University of Messina, Italy.
authors: F
authors: F
authors: Abbate
mesh_terms: D062565:Acid Sensing Ion Channels / Q000378:metabolism* / Q000648:ultrastructure; D000818:Animals; D009928:Organ Specificity / Q000502:physiology; D013650:Taste Buds / Q000378:metabolism* / Q000648:ultrastructure; D014018:Tissue Distribution; D050051:Transient Receptor Potential Channels / Q000378:metabolism*; D015027:Zebrafish / Q000033:anatomy & histology / Q000378:metabolism*
chemical_list: D062565:Acid Sensing Ion Channels; D050051:Transient Receptor Potential Channels
keywords: Acid-sensing ion channels; Taste buds; Transient receptor potential ion channels; Zebrafish