title: Association of nerve conduction impairment and insulin resistance in children with obesity.
abstract: OBJECTIVE
  The objective of our study was to investigate nerve conduction in normoglycemic obese children.
  
  
  METHODS
  A total of 60 children with obesity (30 female and 30 male) and 30 healthy children (15 female and 15 male) were enrolled in the study. Insulin resistance (IR) and other metabolic disturbances were investigated and nerve conduction was measured in all participants. Obese children were divided into groups according to the presence of IR. All results were compared between these subgroups.
  
  
  RESULTS
  The nerve conduction velocity (NCV) of motor median nerves in the IR+ group was significantly higher than that in the IR- group and lower than that in the control group. The NCV of the motor peroneal nerve in the IR+ group was significantly lower than that in the IR- group. The sensory nerve action potential (SNAP) of the sensory median nerve was significantly lower in the IR+ group compared to that in the IR- group. The sensory sural nerve's SNAP was significantly lower in the IR+ group than that in the control group.
  
  
  CONCLUSIONS
  Nerve conduction tests may help to detect early pathologies in peripheral nerves and to decrease morbidities in obese children.
authors: Department of Pediatric Endocrinology, Gülhane Military Medical Academy, Ankara, Turkey. onur3034@hotmail.com.
authors: Onur
authors: O
authors: Akın
authors: Department of Pediatrics, Gülhane Military Medical Academy, Ankara, Turkey.
authors: İbrahim
authors: İ
authors: Eker
authors: Department of Pediatric Neurology, Gülhane Military Medical Academy, Ankara, Turkey.
authors: Mutluay
authors: M
authors: Arslan
authors: Department of Neurology, Gülhane Military Medical Academy, Ankara, Turkey.
authors: Serdar
authors: S
authors: Taşdemir
authors: Department of Pediatric Endocrinology, Gülhane Military Medical Academy, Ankara, Turkey.
authors: Mehmet Emre
authors: ME
authors: Taşçılar
authors: Department of Neurology, Gülhane Military Medical Academy, Ankara, Turkey.
authors: Ümit Hıdır
authors: ÜH
authors: Ulaş
authors: Department of Pediatric Endocrinology, Gülhane Military Medical Academy, Ankara, Turkey.
authors: Ediz
authors: E
authors: Yeşilkaya
authors: Department of Pediatric Neurology, Gülhane Military Medical Academy, Ankara, Turkey.
authors: Bülent
authors: B
authors: Ünay
mesh_terms: D000293:Adolescent; D002648:Child; D004576:Electromyography; D005260:Female; D006801:Humans; D007333:Insulin Resistance / Q000502:physiology*; D008297:Male; D009431:Neural Conduction / Q000502:physiology*; D009765:Obesity / Q000150:complications*
keywords: Children; Nerve conduction study; Obesity