title: Synthesis of Isoindolinones by Pd-Catalyzed Coupling between N-Methoxybenzamide and Styrene Derivatives.
abstract: An atom-economical protocol for a tandem process involving Fujiwara-Moritani-aza-Wacker reactions has been developed for the Pd-catalyzed coupling between N-methoxy benzamide and styrene derivatives. The generality of the methodology was demonstrated by the synthesis of a library of 25 3-benzylidene isoindolinones in moderate to good yields. A further 40 3-benzyl derivatives were obtained by telescoping the process with a catalytic hydrogenation reaction.
authors: Department of Chemistry, Imperial College London , Exhibition Road, South Kensington, London SW7 2AZ, U.K.
authors: Changkun
authors: C
authors: Xia
authors: Department of Chemistry, Imperial College London , Exhibition Road, South Kensington, London SW7 2AZ, U.K.
authors: Andrew J P
authors: AJP
authors: White
authors: Department of Chemistry, Imperial College London , Exhibition Road, South Kensington, London SW7 2AZ, U.K.
authors: King Kuok Mimi
authors: KKM
authors: Hii