title: Domino [Pd]-Catalysis: One-Pot Synthesis of Isobenzofuran-1(3H)-ones.
abstract: An efficient domino [Pd]-catalysis for the synthesis of isobenzofuran-1(3H)-ones is presented. The strategy shows broad substrate scope and is amenable to o-bromobenzyl tertiary/secondary/primary alcohols. Significantly, the method was applied to the synthesis of antiplatelet drug n-butyl phthalide and cytotoxic agonist 3a-[4'-methoxylbenzyl]-5,7-dimethoxyphthalide.
authors: Department of Chemistry, Indian Institute of Technology Hyderabad , Kandi-502 285, Sangareddy, Medak District, Telangana, India.
authors: Lodi
authors: L
authors: Mahendar
authors: Department of Chemistry, Indian Institute of Technology Hyderabad , Kandi-502 285, Sangareddy, Medak District, Telangana, India.
authors: Gedu
authors: G
authors: Satyanarayana