title: Extranodal NK/T Cell Lymphoma Causing Cardiorespiratory Failure.
abstract: Extranodal NK/T cell lymphoma is an uncommon malignancy usually involving the sinonasal area. We report an unusual case of extranodal NK/T cell lymphoma diagnosed in a 62-year-old Caucasian male who died of progressive cardiorespiratory failure but had no clinically detectable upper respiratory system lesions. The initial diagnosis was made cytologically on a sample of pericardial fluid that contained neoplastic lymphoid cells. These cells were positive for CD2, cytoplasmic CD3, and Epstein-Barr virus and negative for CD56. The diagnosis was confirmed at the autopsy, which disclosed lymphoma infiltrates in the myocardium, lungs, stomach, and pancreas. The death was caused by heart and lung failure due to uncontrollable arrhythmia and respiratory insufficiency due to the lymphoma infiltrates. To the best of our knowledge, this is the first case of extranodal NK/T cell lymphoma presenting with cardiopulmonary failure.
authors: Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard MS 3045, Kansas City, KS 66160, USA.
authors: Yiting
authors: 0000-0001-9155-1403
authors: Y
authors: Li
authors: Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Boulevard MS 3045, Kansas City, KS 66160, USA.
authors: Ivan
authors: 0000-0002-1394-6052
authors: I
authors: Damjanov