title: Increased Gastric Activity on Myocardial Perfusion Imaging.
abstract: We anecdotally observed an increased accumulation of (99m)Tc-tetrofosmin in the stomach of myocardial perfusion patients when their uptake phase coincided with preparation of hamburgers in an adjacent room for gastric emptying studies on other patients. The potential for a scent-stimulated alteration of gastric biodistribution required further investigation.
  
  
  METHODS
  An experimental group and a control group were enrolled (20 patients per group). The experimental group could smell food being prepared during the uptake phase. Stomach, heart, and background regions were drawn in multiple projections, and the resulting data were evaluated.
  
  
  RESULTS
  The experimental and control groups did not significantly differ in stomach counts per pixel, background-corrected counts per pixel, or heart-to-stomach ratio. Further analysis of the data revealed that women had a significantly higher increase in stomach counts (P = 0.022) and background-corrected stomach counts (P = 0.018) than men.
  
  
  CONCLUSIONS
  Women had a greater increase in gastric (99m)Tc-tetrofosmin activity than men during the radiopharmaceutical uptake phase, but there was no causal relationship between an increase in activity and olfactory stimulation from the cooking of food.
authors: Faculty of Science, Charles Sturt University, Wagga Wagga, Australia.
authors: Grace
authors: G
authors: Brayshaw
authors: Department of Nuclear Medicine, Canberra Hospital, Canberra, Australia; and.
authors: Sharon
authors: S
authors: Mosley
authors: Faculty of Science, Charles Sturt University, Wagga Wagga, Australia Faculty of Medicine and Health Sciences, Macquarie University, Sydney, Australia gcurrie@csu.edu.au.
authors: Geoff
authors: G
authors: Currie
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D005753:Gastric Mucosa / Q000378:metabolism; D006801:Humans; D008297:Male; D008875:Middle Aged; D055414:Myocardial Perfusion Imaging; D009943:Organophosphorus Compounds / Q000378:metabolism; D015609:Organotechnetium Compounds / Q000378:metabolism; D012189:Retrospective Studies; D012903:Smell; D013270:Stomach / Q000000981:diagnostic imaging* / Q000502:physiology*
chemical_list: D009943:Organophosphorus Compounds; D015609:Organotechnetium Compounds; C078700:technetium tc-99m tetrofosmin
keywords: cardiology; gastric; myocardial perfusion; quality assurance; stomach; tetrofosmin