title: [Prognostic significance of the culprit vessel in patients with ST-elevation myocardial infarction treated with primary coronary intervention].
abstract: BACKGROUND
  To the best of the authors' knowledge, very few publications are available which report on the prognostic significance of the culprit vessel in patients with ST elevation myocardial infarction treated with successful primary percutaneous coronary intervention.
  
  
  OBJECTIVE
  The aim of the authors was to obtain data on the significance of the culprit vessel in patients with ST elevation myocardial infarction treated successfully by primary percutaneous coronary intervention.
  
  
  METHODS
  The authors performed a retrospective study in 10,763 patients with ST elevation myocardial infarction who underwent successful primary percutaneous coronary intervention. The culprit vessels were the left main artery, left anterior descendent artery, left circumflex artery, and right coronary artery. The authors constructed univariate survival curves for different culprit vessels and also performed multivariate modelling of time-to-death, controlling for age, sex, and comorbidities.
  
  
  RESULTS
  The majority of the culprit lesions were found in the left anterior descendent artery (44.3%), the right coronary artery (40.9%), and the left circumflex artery (13.7%). The culprit vessel was overall a highly significant (p<0.0001) factor of survival, with right coronary artery exhibiting a highly significantly better prognosis (hazard ratio 0.69, 95% CI 0.61-0.79, p<0.0001) and left main artery exhibiting a significantly worse prognosis (hazard ratio 1.56, 95% CI 1.04-2.35, p = 0.0321) than the reference vessel (left anterior descendent artery).
  
  
  CONCLUSIONS
  These data demonstrate that the culprit vessel has independent prognostic significance. Orv. Hetil., 2016, 157(32), 1282-1288.
authors: Gottsegen György Országos Kardiológiai Intézet Budapest, Haller u. 29., 1096.
authors: András
authors: A
authors: Jánosi
authors: Gottsegen György Országos Kardiológiai Intézet Budapest, Haller u. 29., 1096.
authors: Péter
authors: P
authors: Ofner
authors: Gottsegen György Országos Kardiológiai Intézet Budapest, Haller u. 29., 1096.
authors: Dániel
authors: D
authors: Simkovits
authors: Élettani Szabályozások Csoport, Óbudai Egyetem, Neumann János Informatikai Kar Budapest.
authors: Tamás
authors: T
authors: Ferenci
mesh_terms: D000328:Adult; D000368:Aged; D002317:Cardiovascular Agents / Q000627:therapeutic use*; D017023:Coronary Angiography; D003327:Coronary Disease / Q000175:diagnosis / Q000601:surgery; D003331:Coronary Vessels / Q000601:surgery*; D005260:Female; D006329:Heart Conduction System / Q000503:physiopathology*; D006801:Humans; D008297:Male; D008875:Middle Aged; D009203:Myocardial Infarction / Q000503:physiopathology / Q000517:prevention & control / Q000601:surgery*; D010351:Patient Discharge; D062645:Percutaneous Coronary Intervention; D011237:Predictive Value of Tests; D011379:Prognosis; D012189:Retrospective Studies; D055502:Secondary Prevention / Q000379:methods
chemical_list: D002317:Cardiovascular Agents
keywords: ST elevation myocardial infarction; ST-elevációs myocardialis infarctus; culprit vessel; infarktusért felelős ér; percutan coronariaintervenció; percutaneous coronary intervention; prognosis; prognózis