title: High-frequency rTMS on leg motor area in the early phase of stroke.
abstract: Although repetitive transcranial magnetic stimulation (rTMS) for upper limb motor area in stroke patients is beneficial, it has been poorly investigated in rTMS for leg motor area. Furthermore, no study has examined the usefulness of rTMS for leg motor area in patients in the early phase of stroke. Twenty-one patients with a hemispheric stroke lesion in the early phase were randomly assigned into two groups: the high-frequency (HF)-rTMS group [N = 11] and the sham stimulation group [N = 10]. Patients received rTMS for 5 consecutive days, beginning 10.9 ± 6.6 days on average after the onset. Brunnstrom Recovery Stages (BRS) for the lower limbs and the Ability for Basic Movement Scale Revised (ABMS II) were assessed before and after the intervention. The improvement in BRS for the lower limbs was significant after the intervention in the HF-rTMS group. Although both the HF-rTMS and sham stimulation groups had significant improvements in ABMS II scores, the extent of improvement in the AMBS II was significantly greater in the HF-rTMS group than in the sham stimulation group. Application of HF-rTMS over the bilateral leg motor areas has potential to be a new rehabilitation therapy for patients in the acute phase of stroke.
authors: Department of Rehabilitation Medicine, International University of Health and Welfare Atami Hospital, 13-1, Higashi Kaigan-cho, Atami-Shi, Shizuoka, 413-0012, Japan. nobsasa1005@gmail.com.
authors: Nobuyuki
authors: N
authors: Sasaki
authors: Department of Rehabilitation Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-Ku, Tokyo, 105-8461, Japan.
authors: Masahiro
authors: M
authors: Abo
authors: Department of Rehabilitation Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-Ku, Tokyo, 105-8461, Japan.
authors: Takatoshi
authors: T
authors: Hara
authors: Department of Rehabilitation Medicine, The Jikei University School of Medicine, 3-25-8, Nishi-Shimbashi, Minato-Ku, Tokyo, 105-8461, Japan.
authors: Naoki
authors: N
authors: Yamada
authors: Department of Rehabilitation Medicine, Tokyo Metropolitan Bokutoh Hospital, 4-23-15, Koutoh-Bashi, Sumida-Ku, Tokyo, 130-8575, Japan.
authors: Masachika
authors: M
authors: Niimi
authors: Department of Rehabilitation Medicine, International University of Health and Welfare Mita Hospital, 1-4-3, Mita, Minato-Ku, Tokyo, 108-8329, Japan.
authors: Wataru
authors: W
authors: Kakuda
mesh_terms: D000328:Adult; D000368:Aged; D000369:Aged, 80 and over; D005260:Female; D006801:Humans; D007866:Leg / Q000294:innervation; D008297:Male; D008875:Middle Aged; D009044:Motor Cortex; D010865:Pilot Projects; D020127:Recovery of Function; D020521:Stroke / Q000628:therapy*; D050781:Transcranial Magnetic Stimulation / Q000379:methods*
keywords: Early phase; Leg motor area; Lower limb; Rehabilitation; Repetitive transcranial magnetic stimulation