title: Burden of Rotavirus Diarrhea in Under five Indian Children.
abstract: OBJECTIVE
  Rotavirus is the most common cause of severe diarrhea in infants and young children worldwide. The burden of rotavirus diarrhea in Indian children is not well established. The present study reviewed the epidemiology of rotavirus diarrhea in hospitalized children and in the community, molecular serotyping and under-five mortality caused by rotavirus diarrhea.
  
  
  METHODS
  Publications, reporting rotavirus diarrhea in Indian children, were retrieved through a systematic search of databases including Medline, PubMed, IndMed, websites of WHO, UNICEF, National Family Health Survey, Ministry of Health and Family Welfare, and Government of India. Human studies in English language were included. Age group selected was 0 month to 5 years. No restrictions were applied in terms of study design and time frame.
  
  
  CONCLUSIONS
  Stool sample positivity varied from 4.6% in Kolkata to 89.8% in Manipur, among hospitalized children, and from 4% in Delhi to 33.7% in Manipur in community. Most cases of rotavirus diarrhea in India are caused by G1, G2, and G untypeable strains with distinct regional variations. Rotavirus was identified as an etiological agent in 5.2 to 80.5% cases of nosocomial diarrhea. Data are lacking for rotavirus mortality.
authors: Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, India and Indian Academy of Pediatrics, Kailash Darshan, Kennedy Bridge, Mumbai, India. Correspondence to: Professor Ashok Kumar, Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi 221 005, India. ashokkumar_bhu@hotmail.com.
authors: Ashok
authors: A
authors: Kumar
authors: Sriparna
authors: S
authors: Basu
authors: Vipin
authors: V
authors: Vashishtha
authors: Panna
authors: P
authors: Choudhury
mesh_terms: D002675:Child, Preschool; D017281:Cost of Illness; D003967:Diarrhea / Q000453:epidemiology* / Q000401:mortality / Q000821:virology; D005260:Female; D005759:Gastroenteritis / Q000453:epidemiology / Q000401:mortality / Q000821:virology; D006801:Humans; D015994:Incidence; D007194:India / Q000453:epidemiology; D007223:Infant; D007231:Infant, Newborn; D008297:Male; D015995:Prevalence; D012401:Rotavirus; D012400:Rotavirus Infections / Q000453:epidemiology* / Q000401:mortality / Q000821:virology