title: The Novel Application of Genomic Profiling Assays to Shorten Inactive Status for Potential Kidney Transplant Recipients With Breast Cancer.
abstract: The concern about cancer recurrence has traditionally resulted in delaying kidney transplantation for 2-5 years after a cancer diagnosis in patients who are otherwise eligible for transplant. This period of inactive status to observe the tumor biology can result in significant morbidity and decreased quality of life for patients with end-stage renal disease (ESRD). We reported the novel application of genomic profiling assays in breast cancer to identify low-risk cancers in two patients with ESRD who were able to have the mandatory inactive status eliminated prior to kidney transplantation.
authors: Department of Surgery, University of California, San Francisco, San Francisco, CA.
authors: R A
authors: RA
authors: Mukhtar
authors: Department of Surgery, University of California, San Francisco, San Francisco, CA.
authors: M L
authors: ML
authors: Piper
authors: Department of Surgery, University of California, San Francisco, San Francisco, CA.
authors: C
authors: C
authors: Freise
authors: Department of Surgery, University of California, San Francisco, San Francisco, CA.
authors: L J
authors: LJ
authors: Van't Veer
authors: Department of Anatomic Pathology, University of California, San Francisco, San Francisco, CA.
authors: F L
authors: FL
authors: Baehner
authors: Department of Surgery, University of California, San Francisco, San Francisco, CA.
authors: L J
authors: LJ
authors: Esserman
mesh_terms: D014408:Biomarkers, Tumor / Q000235:genetics*; D001943:Breast Neoplasms / Q000235:genetics / Q000473:pathology*; D005260:Female; D020869:Gene Expression Profiling; D023281:Genomics; D006801:Humans; D016030:Kidney Transplantation; D008875:Middle Aged; D009364:Neoplasm Recurrence, Local / Q000175:diagnosis* / Q000235:genetics; D011379:Prognosis; D012307:Risk Factors; D066027:Transplant Recipients
chemical_list: D014408:Biomarkers, Tumor
keywords: biomarker; cancer/malignancy/neoplasia; cancer/malignancy/neoplasia: risk factors; clinical research/practice; hematology/oncology; immunogenetics; kidney transplantation/nephrology; translational research/science