title: Expanding the spectrum of systemic amyloid diseases: a new hint from the kidney.
abstract: Proteomics-based assays have substantially improved diagnostic accuracy in systemic amyloidosis and have led to the discovery of novel amyloidogenic proteins. The observation that human apolipoproteins are increasingly represented is intriguing and highlights the complex, and partially known, mutual effects of the misfolded proteins and lipids. Dasari et al. report on the first series of patients affected by the recently described apolipoprotein A-IV amyloidosis, detailing its peculiar clinical and pathologic findings and diagnostic pitfalls.
authors: Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Pavia, Italy.
authors: Laura
authors: L
authors: Obici
authors: Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy.
authors: Mario
authors: M
authors: Nuvolone
authors: Amyloidosis Research and Treatment Center, Foundation IRCCS Policlinico San Matteo, Pavia, Italy; Department of Molecular Medicine, University of Pavia, Pavia, Italy. Electronic address: gmerlini@unipv.it.
authors: Giampaolo
authors: G
authors: Merlini
mesh_terms: D000682:Amyloid; D000686:Amyloidosis; D001054:Apolipoproteins A; D006801:Humans; D007668:Kidney; D007674:Kidney Diseases; D009101:Multiple Myeloma
chemical_list: D000682:Amyloid; D001054:Apolipoproteins A; C022205:apolipoprotein A-IV