title: Thiol/disulfide parameters as a novel oxidative marker in medical labor induction with oxytocin.
abstract: BACKGROUND
  The aim of this study was to analyze the alterations in thiol levels among mothers and neonates who were prone to medical oxytocin induction.
  
  
  METHODS
  A total of 40 pregnant women who underwent medical labor induction with oxytocin (Group A) were compared with 53 women whose labor progressed spontaneously without any kind of induction (Group B). We measured the thiol/disulfide homeostasis parameters (native thiol, total thiol, disulfide, disulfide/total thiol, disulfide/native thiol) of maternal and cord blood.
  
  
  RESULTS
  There were no statistically significant differences with respect to the maternal and cord blood thiol/disulfide homeostasis between the two groups.
  
  
  CONCLUSIONS
  Being an artificial intervention during labor, oxytocin induction has been found to be safe in terms of oxidative stress (OS) according to the results of this study. Both the maternal and the fetal sides were safe in this molecular manner against oxytocin infusion.
authors: Ozlem Gun
authors: OG
authors: Eryilmaz
authors: Hatice
authors: H
authors: Kansu-Celik
authors: Ozcan
authors: O
authors: Erel
authors: Serpil
authors: S
authors: Erdogan
mesh_terms: D000328:Adult; D015415:Biomarkers / Q000097:blood*; D003430:Cross-Sectional Studies; D004220:Disulfides / Q000097:blood*; D005260:Female; D005312:Fetal Blood / Q000378:metabolism; D006706:Homeostasis; D006801:Humans; D007231:Infant, Newborn; D007751:Labor, Induced; D018384:Oxidative Stress; D010120:Oxytocics / Q000008:administration & dosage; D010121:Oxytocin / Q000008:administration & dosage*; D011247:Pregnancy; D011446:Prospective Studies; D013438:Sulfhydryl Compounds / Q000097:blood*
chemical_list: D015415:Biomarkers; D004220:Disulfides; D010120:Oxytocics; D013438:Sulfhydryl Compounds; D010121:Oxytocin