title: Dataset and standard operating procedure for newborn screening of six lysosomal storage diseases: By tandem mass spectrometry.
abstract: In this data article we provide a detailed standard operating procedure for performing a tandem mass spectrometry, multiplex assay of 6 lysosomal enzymes for newborn screening of the lysosomal storage diseases Mucopolysaccharidosis-I, Pompe, Fabry, Niemann-Pick-A/B, Gaucher, and Krabbe, (Elliott, et al., 2016) [1]. We also provide the mass spectrometry peak areas for the product and internal standard ions typically observed with a dried blood spot punch from a random newborn, and we provide the daily variation of the daily mean activities for all 6 enzymes.
authors: Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
authors: Susan
authors: S
authors: Elliott
authors: Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
authors: Norman
authors: N
authors: Buroker
authors: PerkinElmer, Waltham, MA 02451, USA.
authors: Jason J
authors: JJ
authors: Cournoyer
authors: PerkinElmer, Waltham, MA 02451, USA.
authors: Anna M
authors: AM
authors: Potier
authors: PerkinElmer, Waltham, MA 02451, USA.
authors: Joseph D
authors: JD
authors: Trometer
authors: PerkinElmer, Waltham, MA 02451, USA.
authors: Carole
authors: C
authors: Elbin
authors: PerkinElmer, Waltham, MA 02451, USA.
authors: Mack J
authors: MJ
authors: Schermer
authors: PerkinElmer, Turku 20750, Finland.
authors: Jaana
authors: J
authors: Kantola
authors: Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
authors: Aaron
authors: A
authors: Boyce
authors: Department of Chemistry, University of Washington, Seattle, WA 98195, USA.
authors: Frantisek
authors: F
authors: Turecek
authors: Department of Chemistry, University of Washington, Seattle, WA 98195, USA.
authors: Michael H
authors: MH
authors: Gelb
authors: Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
authors: C Ronald
authors: CR
authors: Scott