title: Probable glucometer interference caused by topical iodine solution test site preparation.
abstract: OBJECTIVE
  Use of disinfectants, such as alcohol prep pads, for test site preparation have demonstrated alterations in glucose readings. One case report details an overestimation of blood glucose (BG) readings when using Chemstrip bG and Visidex reagent test strips after cleaning test site with povidone-iodine swabs
  
  
  METHODS
  We present a case of a clinically relevant probable drug-device interaction between topical iodine and a point-of-care glucometer in a 28 year old pregnant woman of Chinese descent. In this case, the use of 10% povidone-iodine solution on the testing site before lancing likely resulted in variable and inaccurate BG readings, which was not reproduced when the patient used hand washing instead of iodine.
  
  
  CONCLUSIONS
  Our report expands on this prior knowledge by demonstrating that such an alteration associated with iodine can occur with modern electrochemical glucometers. In patients that have aberrant or variable BG readings, providers should investigate for improper testing technique.
authors: Department of Pharmacy, Mount Carmel West Hospital, Columbus, OH, USA.
authors: A M
authors: AM
authors: Lipshutz
authors: Department of Pharmacy, UNC Medical Center, Chapel Hill, NC, USA.|UNC Eshelman School of Pharmacy, Chapel Hill, NC, USA.|Department of Family Medicine, UNC School of Medicine, Chapel Hill, NC, USA.
authors: E M
authors: EM
authors: Hawes
mesh_terms: D000328:Adult; D001786:Blood Glucose / Q000032:analysis*; D005260:Female; D006801:Humans; D007202:Indicators and Reagents / Q000737:chemistry; D007455:Iodine / Q000009:adverse effects*; D019095:Point-of-Care Systems; D011247:Pregnancy; D011934:Reagent Strips / Q000737:chemistry*
chemical_list: D001786:Blood Glucose; D007202:Indicators and Reagents; D011934:Reagent Strips; D007455:Iodine
keywords: ambulatory care; disinfectant; gestational diabetes; glucose testing; iodine