title: Type 2 Diabetes Treatment in the Patient with Obesity.
abstract: Lifestyle modification is the cornerstone treatment of type 2 diabetes in the obese patient, and is highly effective at promoting glucose regulation. However, many individuals struggle over time to maintain optimal glycemic control and/or body weight with lifestyle modification. Therefore, additional therapeutic approaches are needed. Pharmacologic interventions have shown promising results for obesity-related diabetes complications. Not surprisingly though lifestyle modification and pharmacology may become ineffective for treating diabetes over time. Bariatric surgery is considered by some, but not all, to be the most effective and durable treatment for combating obesity. In fact many patients with type 2 diabetes have normalized glucose concentrations within days postoperation. Taken together, treatment of obesity in the patient with type 2 diabetes requires a multi-faceted approach.
authors: Division of Endocrinology & Metabolism, Department of Kinesiology, Curry School of Education, School of Medicine, University of Virginia, 203 Memorial Gymnasium, Charlottesville, VA 22904, USA.
authors: Steven K
authors: SK
authors: Malin
authors: Division of Endocrinology, School of Medicine, Department of Endocrinology, Diabetes, and Metabolism, Cleveland Clinic, 9500 Euclid Avenue, NE40, Cleveland, OH 44195, USA. Electronic address: kashyas@ccf.org.
authors: Sangeeta R
authors: SR
authors: Kashyap
mesh_terms: D001786:Blood Glucose; D048909:Diabetes Complications; D003924:Diabetes Mellitus, Type 2 / Q000150:complications / Q000628:therapy*; D006801:Humans; D008019:Life Style; D009765:Obesity / Q000150:complications* / Q000601:surgery
chemical_list: D001786:Blood Glucose
keywords: Bariatric surgery; Diet; Exercise; Glycemic control; Insulin resistance; Pharmacology; β-cell function