title: Unhealthy Sugars in Bacterial Cytotoxicity.
abstract: Bacterial type three secretion systems (T3SSs) are central to virulence, but the processes stimulating their activation are unclear. In this issue of Cell Host & Microbe, Blondel et al. (2016) perform a genome-wide screen using CRISPR/Cas technology to identify a role for cell surface sulfation and fucosylation in cytotoxicity mediated by Vibrio parahaemolyticus T3SSs.
authors: Equipe Communication Intercellulaire et Infections Microbiennes, Centre de Recherche Interdisciplinaire en Biologie (CIRB), Collège de France, 75005 Paris, France; Institut National de la Santé et de la Recherche Médicale (Inserm) U1050, 75654 Paris Cedex 13, France; Centre National de la Recherche Scientifique (CNRS) UMR7241, 75794 Paris Cedex 16, France; MEMOLIFE Laboratory of excellence and Paris Sciences et Lettres, 75005 Paris, France.
authors: D Isui
authors: DI
authors: Aguilar-Salvador
authors: Equipe Communication Intercellulaire et Infections Microbiennes, Centre de Recherche Interdisciplinaire en Biologie (CIRB), Collège de France, 75005 Paris, France; Institut National de la Santé et de la Recherche Médicale (Inserm) U1050, 75654 Paris Cedex 13, France; Centre National de la Recherche Scientifique (CNRS) UMR7241, 75794 Paris Cedex 16, France; MEMOLIFE Laboratory of excellence and Paris Sciences et Lettres, 75005 Paris, France. Electronic address: guy.tran-van-nhieu@college-de-france.fr.
authors: Guy
authors: G
authors: Tran Van Nhieu
mesh_terms: D001426:Bacterial Proteins; D058947:Bacterial Secretion Systems; D001427:Bacterial Toxins; D014736:Vibrio parahaemolyticus; D037521:Virulence Factors
chemical_list: D001426:Bacterial Proteins; D058947:Bacterial Secretion Systems; D001427:Bacterial Toxins; D037521:Virulence Factors