title: Priority of Treatment Outcomes for Caregivers and Patients with Mild Cognitive Impairment: Preliminary Analyses.
abstract: BACKGROUND
  The patient-centered movement advocates for greater attention to the outcomes that matter most to patients and their families. In neurodegenerative disease, determination of patient and caregiver priorities has received scant attention in part because dementia patients are deemed unreliable reporters. However, people with mild cognitive impairment (MCI) likely retain capacity to report their preferences.
  
  
  METHODS
  In two separate MCI cohorts, we conducted preliminary analyses of patient and caregiver priorities among seven patient and five caregiver outcomes of the HABIT®Healthy Action to Benefit Independence & Thinking program (Mayo Clinic, Rochester, MN, USA).
  
  
  RESULTS
  Via interview and paper-and-pencil reporting both patient and caregiver respondents' ranked patient and caregiver quality of life and patient self-efficacy as highest priorities, ranking them ahead of patient and caregiver mood, patient functional status, patient distressing behaviors and caregiver burden. Patients and caregivers tended to value the outcomes for their loved ones higher than their own outcomes.
  
  
  CONCLUSIONS
  Caregivers appeared to be reasonable, but not perfect, proxies for patient reports. Additional research with larger cohorts and a more comprehensive range of outcomes is needed.
authors: Ponce School of Medicine & Health Sciences, Ponce, Puerto Rico.
authors: Polaris González
authors: PG
authors: Barrios
authors: Ponce School of Medicine & Health Sciences, Ponce, Puerto Rico.
authors: Ricardo Pabón
authors: RP
authors: González
authors: Division of Neurocognitive Disorders, Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.
authors: Sherrie M
authors: SM
authors: Hanna
authors: Division of Neurocognitive Disorders, Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.
authors: Angela M
authors: AM
authors: Lunde
authors: Division of Neurocognitive Disorders, Department of Psychiatry & Psychology, Mayo Clinic, Rochester, MN, USA.
authors: Julie A
authors: JA
authors: Fields
authors: Department of Psychiatry & Psychology, Mayo Clinic, Scottsdale, AZ, USA.
authors: Dona E C
authors: DE
authors: Locke
authors: Department of Clinical and Health Psychology, University of Florida, Gainesville, USA. glennsmith@phhp.ufl.edu.
authors: Glenn E
authors: http://orcid.org/0000-0003-1506-9484
authors: GE
authors: Smith
keywords: Alzheimer’s disease; Caregivers; Mild cognitive impairment; Patient preference; Quality of life